YaqingLiu/PoN: Generate the Panel of Normal files for TNseq and TNscope.

Generate the Panel of Normal files for TNseq and TNscope.

YaqingLiu 3196be9d29 Fix bug: basename		4年前
tasks	Fix bug: basename	4年前
.DS_Store	Alter: test	4年前
README.md	Add: mergePoN	4年前
defaults	update input	4年前
inputs	Fix bug: sample_id	4年前
workflow.wdl	Fix bug: tumor sample SM tag is not present in the bam file	4年前

README.md

Author: Yaqing Liu

Email: yaqing.liu@outlook.com

Last Updates: 07/04/2021

Requirements

choppy
Ali-Cloud
Linux

Panel of Normals

The Panel of Normals approach uses a set of matched normal samples to determine the baseline level from which to call CNV events. These matched normal samples should be derived from the same library prep and sequencing workflow that was used for the case sample. This allows the algorithm to subtract out system level biases that are not sample specific.

Usage

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