YaqingLiu/PoN: Generate the Panel of Normal files for TNseq and TNscope.

Generate the Panel of Normal files for TNseq and TNscope.

YaqingLiu ba5588de65 Fix bug: tumor_sample parameter		4 年前
tasks	Fix bug: tumor_sample parameter	4 年前
.DS_Store	Alter: test	4 年前
README.md	Add: mergePoN	4 年前
defaults	update input	4 年前
inputs	Fix bug: tumor_sample parameter	4 年前
workflow.wdl	Fix bug: tumor sample SM tag is not present in the bam file	4 年前

README.md

Author: Yaqing Liu

Email: yaqing.liu@outlook.com

Last Updates: 07/04/2021

Requirements

choppy
Ali-Cloud
Linux

Panel of Normals

The Panel of Normals approach uses a set of matched normal samples to determine the baseline level from which to call CNV events. These matched normal samples should be derived from the same library prep and sequencing workflow that was used for the case sample. This allows the algorithm to subtract out system level biases that are not sample specific.

Usage

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