YaqingLiu/PoN: Generate the Panel of Normal files for TNseq and TNscope.

Generate the Panel of Normal files for TNseq and TNscope.

YaqingLiu 53009bc220 Fix bug: basename		před 4 roky
tasks	Fix bug: basename	před 4 roky
.DS_Store	Alter: test	před 4 roky
README.md	Add: mergePoN	před 4 roky
defaults	update input	před 4 roky
inputs	Fix bug: sample_id	před 4 roky
workflow.wdl	Fix bug: tumor sample SM tag is not present in the bam file	před 4 roky

README.md

Author: Yaqing Liu

Email: yaqing.liu@outlook.com

Last Updates: 07/04/2021

Requirements

choppy
Ali-Cloud
Linux

Panel of Normals

The Panel of Normals approach uses a set of matched normal samples to determine the baseline level from which to call CNV events. These matched normal samples should be derived from the same library prep and sequencing workflow that was used for the case sample. This allows the algorithm to subtract out system level biases that are not sample specific.

Usage

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