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### Variant Calling |
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This APP developed for germline and somatic short variant discovery (SNVs + Indels). |
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**Accepted Data** |
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**Accepted data** |
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* TN matched WES for somatic variant calling |
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* TN matched WGS for somatic variant calling |
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* Normal-only WES for germline variant calling |
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@@ -9,33 +10,19 @@ This APP developed for germline and somatic short variant discovery (SNVs + Inde |
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The datatype is judged by whether the bed file is set (i.e. the `regions` in inputs). |
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--- |
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**Supported Callers** |
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* The fields corresponding to these callers include `haplotyper`, `tnseq`, `tnscope`, `varscan`. |
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* All callers are <u>**not activated by default**</u>, which means the default setting is `false`. |
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* You need to manually set the caller to `true` in the submitted sample.csv. |
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<u>***Germline***</u> |
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* Haplotyper |
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<u>***Somatic***</u> |
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* TNseq (TNhaplotyper2) |
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* TNscope |
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* VarScan |
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--- |
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**Supported variant callers and annotation tools** |
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**Annotation Tools** |
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* The fields corresponding to two tools include `annovar`, `vep`. |
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* All tools are <u>**not activated by default**</u>, which means the default setting is `false`. |
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* You need to manually set the caller to `true` in the submitted sample.csv. |
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* Variant calling: |
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* * `haplotyper` (germline) |
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* * `tnseq`, `tnscope`, `varscan` (somatic) |
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* Annotation: `annovar`, `vep`. |
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* The above tools are <u>**not activated by default**</u>, which means the default setting is `false`. You need to manually set the caller to `true` in the submitted sample.csv. |
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### New Releases |
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* Two annotation tools have been added. |
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* TNhaplotyper, named as TNseq in `v0.1.0`, has beed substituted by TNhaplotyper2. |
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* The `corealigner` step has been removed. |
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* The `vcf2maf` step has been removed. Thus, the final output is the annotated `VCF`. |
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* Some parameters' details have been changed, such as the `interval_list` has turned into `interval`. |
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### Getting Started |