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- # Strelka2
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- You don't need to tune the parameters of strelka. It bases on [trained models](<https://github.com/Illumina/strelka/blob/v2.9.x/docs/userGuide/trainingGermlineEmpiricalScore.md>), you may train new models to improve performance.
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- Two steps:
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- 1. Generate the configuration
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- ```bash
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- ```
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- 2. Run Strelka
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- ```bash
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- ```
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- ##### Per sample run time
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- 4h30min
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- ##### Reference
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- 1. Strelka User Guide <https://github.com/Illumina/strelka/blob/v2.9.x/docs/userGuide/README.md>
- 2. Strelka paper <https://www.nature.com/articles/s41592-018-0051-x>
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