# Strelka2

You don't need to tune the parameters of strelka. It bases on [trained models](<https://github.com/Illumina/strelka/blob/v2.9.x/docs/userGuide/trainingGermlineEmpiricalScore.md>), you may train new models to improve performance.





Two steps:

1. Generate the configuration

   ```bash
   
   ```

2. Run Strelka 

   ```bash
   
   ```

##### Per sample run time

4h30min

##### Reference

1. Strelka User Guide <https://github.com/Illumina/strelka/blob/v2.9.x/docs/userGuide/README.md>
2. Strelka paper <https://www.nature.com/articles/s41592-018-0051-x>