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fix: rm germline source

master
YaqingLiu 2 years ago
parent
commit
c550ab8536
2 changed files with 22 additions and 13 deletions
  1. +22
    -11
      tasks/TNseq.wdl
  2. +0
    -2
      workflow.wdl

+ 22
- 11
tasks/TNseq.wdl View File

SAMPLE="--tumor_sample ${tumor_name}" SAMPLE="--tumor_sample ${tumor_name}"
fi fi
# sentieon driver -t $nt -r ${ref_dir}/${fasta} \
# $INPUT $INTERVAL \
# --algo TNhaplotyper2 $SAMPLE \
# --germline_vcf ${germline_resource} \
# ${sample}.TNseq.raw.vcf \
# --algo OrientationBias --tumor_sample ${tumor_name} \
# ${sample}.orientation \
# --algo ContaminationModel $SAMPLE \
# --vcf ${germline_resource} \
# --tumor_segments ${sample}.contamination.segments \
# ${sample}.contamination
# sentieon driver -t $nt \
# -r ${ref_dir}/${fasta} \
# --algo TNfilter $SAMPLE \
# -v ${sample}.TNseq.raw.vcf \
# --contamination ${sample}.contamination \
# --tumor_segments ${sample}.contamination.segments \
# --orientation_priors ${sample}.orientation \
# ${sample}.TNseq.vcf

sentieon driver -t $nt -r ${ref_dir}/${fasta} \ sentieon driver -t $nt -r ${ref_dir}/${fasta} \
$INPUT $INTERVAL \ $INPUT $INTERVAL \
--algo TNhaplotyper2 $SAMPLE \ --algo TNhaplotyper2 $SAMPLE \
--germline_vcf ${germline_resource} \
${sample}.TNseq.raw.vcf \
--algo OrientationBias --tumor_sample ${tumor_name} \
${sample}.orientation \
--algo ContaminationModel $SAMPLE \
--vcf ${germline_resource} \
--tumor_segments ${sample}.contamination.segments \
${sample}.contamination
${sample}.TNseq.raw.vcf
sentieon driver -t $nt \ sentieon driver -t $nt \
-r ${ref_dir}/${fasta} \ -r ${ref_dir}/${fasta} \
--algo TNfilter $SAMPLE \ --algo TNfilter $SAMPLE \
-v ${sample}.TNseq.raw.vcf \ -v ${sample}.TNseq.raw.vcf \
--contamination ${sample}.contamination \
--tumor_segments ${sample}.contamination.segments \
--orientation_priors ${sample}.orientation \
${sample}.TNseq.vcf ${sample}.TNseq.vcf
>>> >>>

+ 0
- 2
workflow.wdl View File

tumor_name=sample_id + ".T", tumor_name=sample_id + ".T",
fasta=fasta, fasta=fasta,
ref_dir=ref_dir, ref_dir=ref_dir,
dbsnp=dbsnp,
dbsnp_dir=dbsnp_dir,
regions=regions, regions=regions,
interval_padding=interval_padding, interval_padding=interval_padding,
germline_resource=germline_resource, germline_resource=germline_resource,

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