VEP (Variant Effect Predictor) predicts the functional effects of genomic variants. The annotated VCF will be converted into MAF based on vcf2maf.
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  1. import "./tasks/VEP.wdl" as VEP
  2. workflow {{ project_name }} {
  3. File vcf
  4. String sample_id
  5. File ref_dir
  6. String fasta
  7. String vep_path
  8. File cache
  9. String ncbi_build
  10. String species
  11. Boolean only_pass
  12. String vcf2maf_path
  13. String vep_docker
  14. String cluster_config
  15. String disk_size
  16. call VEP.VEP as VEP {
  17. input:
  18. vcf=vcf,
  19. sample_id=sample_id,
  20. tumor_id=sample_id + ".T",
  21. normal_id=sample_id + ".N",
  22. ref_dir=ref_dir,
  23. fasta=fasta,
  24. vep_path=vep_path,
  25. cache=cache,
  26. ncbi_build=ncbi_build,
  27. species=species,
  28. only_pass=only_pass,
  29. vcf2maf_path=vcf2maf_path,
  30. docker=vep_docker,
  31. cluster_config=cluster_config,
  32. disk_size=disk_size
  33. }
  34. }