VEP (Variant Effect Predictor) predicts the functional effects of genomic variants. The annotated VCF will be converted into MAF based on vcf2maf.
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  1. import "./tasks/VEP.wdl" as VEP
  2. workflow {{ project_name }} {
  3. File vcf
  4. String sample_id
  5. File ref_dir
  6. String fasta
  7. String vep_path
  8. File cache
  9. String ncbi_build
  10. String species
  11. String vcf2maf_path
  12. String vep_docker
  13. String cluster_config
  14. String disk_size
  15. call VEP.VEP as VEP {
  16. input:
  17. vcf=vcf,
  18. sample_id=sample_id,
  19. tumor_id=sample_id + ".T",
  20. normal_id=sample_id + ".N",
  21. ref_dir=ref_dir,
  22. fasta=fasta,
  23. vep_path=vep_path,
  24. cache=cache,
  25. ncbi_build=ncbi_build,
  26. species=species,
  27. vcf2maf_path=vcf2maf_path,
  28. docker=vep_docker,
  29. cluster_config=cluster_config,
  30. disk_size=disk_size
  31. }
  32. }