VEP (Variant Effect Predictor) predicts the functional effects of genomic variants. The annotated VCF will be converted into MAF based on vcf2maf.
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  1. import "./tasks/vcf2maf.wdl" as vcf2maf
  2. workflow {{ project_name }} {
  3. File vcf
  4. String sample_id
  5. String tumor_id
  6. String normal_id
  7. File ref_dir
  8. String fasta
  9. String vep_path
  10. File cache
  11. String ncbi_build
  12. String species
  13. Boolean only_pass
  14. String vep_docker
  15. String cluster_config
  16. String disk_size
  17. call vcf2maf.vcf2maf as vcf2maf {
  18. input:
  19. vcf=vcf,
  20. sample_id=sample_id,
  21. tumor_id=tumor_id,
  22. normal_id=normal_id,
  23. ref_dir=ref_dir,
  24. fasta=fasta,
  25. vep_path=vep_path,
  26. cache=cache,
  27. ncbi_build=ncbi_build,
  28. species=species,
  29. only_pass=only_pass,
  30. docker=vep_docker,
  31. cluster_config=cluster_config,
  32. disk_size=disk_size
  33. }
  34. }