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task dbsnp location

master
LUYAO REN 5 years ago
parent
commit
dc8f34b180
1 changed files with 6 additions and 6 deletions
  1. +6
    -6
      tasks/VQSR.wdl

+ 6
- 6
tasks/VQSR.wdl View File

set -e set -e
export SENTIEON_LICENSE=192.168.0.55:8990 export SENTIEON_LICENSE=192.168.0.55:8990


resource_text="--resource ${dbsnp_1000G_phase1} \
resource_text="--resource ${ref_dir}/${dbsnp_1000G_phase1} \
--resource_param 1000G,known=false,training=true,truth=false,prior=10.0 " --resource_param 1000G,known=false,training=true,truth=false,prior=10.0 "
resource_text="$resource_text --resource ${dbsnp_1000G_omni} \
resource_text="$resource_text --resource ${ref_dir}/${dbsnp_1000G_omni} \
--resource_param omni,known=false,training=true,truth=true,prior=12.0 " --resource_param omni,known=false,training=true,truth=true,prior=12.0 "
resource_text="$resource_text --resource ${dbsnp} \
resource_text="$resource_text --resource ${ref_dir}/${dbsnp} \
--resource_param dbsnp,known=true,training=false,truth=false,prior=2.0 " --resource_param dbsnp,known=true,training=false,truth=false,prior=2.0 "
resource_text="$resource_text --resource ${dbsnp_hapmap} \
resource_text="$resource_text --resource ${ref_dir}/${dbsnp_hapmap} \
--resource_param hapmap,known=false,training=true,truth=true,prior=15.0" --resource_param hapmap,known=false,training=true,truth=true,prior=15.0"


annotation_array="DP QD FS SOR MQ MQRankSum ReadPosRankSum" annotation_array="DP QD FS SOR MQ MQRankSum ReadPosRankSum"
${SENTIEON_INSTALL_DIR}/bin/sentieon driver -r ${ref_dir}/${fasta} --algo ApplyVarCal -v ${vcf} --var_type SNP --tranches_file ${sample}.vqsrSNP.hc.tranches --sensitivity 99.0 --recal ${sample}.vqsrSNP.hc.recal ${sample}.vqsrSNP.hc.recaled.vcf.gz ${SENTIEON_INSTALL_DIR}/bin/sentieon driver -r ${ref_dir}/${fasta} --algo ApplyVarCal -v ${vcf} --var_type SNP --tranches_file ${sample}.vqsrSNP.hc.tranches --sensitivity 99.0 --recal ${sample}.vqsrSNP.hc.recal ${sample}.vqsrSNP.hc.recaled.vcf.gz
${SENTIEON_INSTALL_DIR}/bin/sentieon plot vqsr -o ${sample}.vqsrSNP.pdf ${sample}.vqsrSNP.hc.plotfile ${SENTIEON_INSTALL_DIR}/bin/sentieon plot vqsr -o ${sample}.vqsrSNP.pdf ${sample}.vqsrSNP.hc.plotfile


resource_text="$resource_text --resource ${dbsnp_Mill} \
resource_text="$resource_text --resource ${ref_dir}/${dbsnp_Mill} \
--resource_param Mills,known=false,training=true,truth=true,prior=12.0 " --resource_param Mills,known=false,training=true,truth=true,prior=12.0 "
resource_text="$resource_text --resource ${dbsnp} \
resource_text="$resource_text --resource ${ref_dir}/${dbsnp} \
--resource_param dbsnp,known=true,training=false,truth=false,prior=2.0 " --resource_param dbsnp,known=true,training=false,truth=false,prior=2.0 "


annotation_array="QD DP FS SOR MQ ReadPosRankSum" annotation_array="QD DP FS SOR MQ ReadPosRankSum"

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