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Strelka2
You don’t need to tune the parameters of strelka. It bases on trained models, you may train new models to improve performance.
Two steps:
- Generate the configuration
- Run Strelka
Per sample run time
4h30min
Reference
- Strelka User Guide https://github.com/Illumina/strelka/blob/v2.9.x/docs/userGuide/README.md
- Strelka paper https://www.nature.com/articles/s41592-018-0051-x