Fusioncatcher/test_input_output/input/reads_2.fq

@000
GTAACTGTCCAAAAGCCATGAAGAGATTAATGGCAGAGTGCCTCAAAAAGAAAAGAGATGAGAGACCACTCTTTCCCCAAATTCTCGCCTCTATTGAGCTG
+
@=?DDEFFGHHHHGEGEEGGCGIIIIGEHHHH<;EGAH>BBHGBFGIGCHGGIJIGGIJGIJGFEIIGEE>CEEDBE@DD@EC@A@@B?BBCDDEDCDACA
@001
CAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGG
+
???;DBDDADDDDEE:?ECE3A?BEE8):CDDDDB4C3?DDADIIID<=;BBCACC7@CEDDD9;37;;?>;@D;BDA>>AAA?1=?A355<<???>A>>>
@002
GCTTCTCTGTGGAACTGGAAAGTGAAATTTCAACCACAGCAGATGACTGCAGTTCAGAGGTAAATGGTTGCAGTTTTGTGATGAGAACAGGAAAGCCTAC
+
CC@FFFFFHDHHHJIJIJIJIJFCHHIJJJJJJJJJIIGIIIJHIJJJIJIJGIHJJJJJHIJIJJJ=@GIJJIJHHGCHCDFFFFDEDEDBDDDDDDCD
@003
CTCTTGGATATATGCCATACCCCAGCAAAAGCAACCAGGAAGTTCTGGGGTTTGTCACCAGTGGAGGCCGGATGGACCCACCCAAGAACTGCCCTGGGCCT
+
?@<DDDDD<FH:CAEGF?FHGG@GC3A@CF3?DF@3;):B)00??DD@).7@FF@@G=3CC=@9)6?;(9A;'3;:59<2?;9<(81<9@(((2:(+2(+8
@004
CGACGAGATTGAAATCGACTTTGAGACCCTGAAGCCGTCCACACTGCGTGAGCTGGAGCGCTATGTCACCTCCTGTTTGCGGAAGAAAAGGAAACCTCA
+
@<;DDDDFDHFDDGHGIGIGHHIIIIGCHI@DEFFEDHHBHGIGGG>A;@@EEEEE>BBBCCBBCDDECCCCCCCCCCCCBB@BBBCCCC?BCC>?>AA
@005
ACCAGATAATTTTTATGGTGGGACGAGGATACCTGTCTCCAGATCTCAGTAAGGTACGGAGTAACTGTCCAAAAGCCATGAAGAGATTAATGGCAGAGTGC
+
CCCFFFFFHHHHHJJJJJGIJJJJJJJJIIJJJJJJJJJJJJIJJJJJJHHIIJ@GHJJJHEEHHFFEFFFEEDDEDDDDDDDDDCDDDDDCDDDDDD:@A
@006
GCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATAC
+
CCCFFFFFGHHHHJJJJJJJJJIIJJJJJJJIJIIDGJJIIIJIJIIJIIJIJIIIHHHHFFFFFEEDEEEDDDDDDDDCDDDDBDDDDDDBCDCDDDCDD
@007
CTCCTTCGGAGTTGCACAAGGTCCACGGATCCAGAAACAAGCCCACCAGCTTGTGGAACCCAACGTACGGCTCCTGGTTTACAGAGAAACCCACCAAAA
+
CCCFFFFFHHHHHJJJJJJJJHHIJJJJJJJJJJJJJJJJJJJJJJJJIJJJJHIJHHHHFFFFDCEDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDD
@008
AGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCAAGCCCACT
+
@CCDFFFFGFFGHIGIIJIIJIIJIIFHHHIJJJJJJJJIJJIIIJJJIIIAEHHHFFFFFEEEDDDDDDDDDDDDDDDEDDEDDDDDDBDD&9?@BDB?A
@009
CTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJIJJJJJJJJIJJJJJJIIJJJJJJJJJJIJJJJJJIJIJHHGHFFFFFFEEEEEEEDDDDDDDDDDDDDDBDDD
@00A
TACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTTATGGGC
+
@<@DDDDDHFHBHIGFEGGHIIHIEHICHIBGI;FGC?F>GHGGGHIIIIDHDGCGEGHIIIHFFBDEBCCCBBBBBBBBCCCCCECBB><>BCCCCCB8
@00B
CGGATAATGACTCAGTGCTGGCAACATCAGCCTGAAGACAGGCACAACTTTGCCATCATTTTGGAGAGGATTGAATACTGCACCCAGGACCCGGATGTAAT
+
1;8:B)=DD>D:AEB:C:AC<<FFI99F9+:E@>EDAADDCCDDIDCDEBDDDADAD@CEIEII;AE;;=A?;AAADA;>(;;A??5=?<??==;90(+::
@00C
GATGTTTTGAGGCGTCTTGCAATCTCTGAAGATCATGTGGCCTCAGTGAAAAAATCAGTCTCAAGTAAAGGCCAACCAAGCCCTCGAGCAGTTATTCCCAT
+
?@@A:A==CFHD=G?EGG@BEDHDCFDAEDGEGEGDG?D@?AGHHHD<=CGEGEGIE@=AEEHCABBDD>CCCCC?/?B=<?@CB=B><@C4>AC@@CCCC
@00D
GGAAGATTTAGAAATTGAACATCGAATAAATATTGAAAAACTTAAAGATAATTTAGGCATTCACTATAAACAGCAGATAGATGGTTTACAGAATGAAATG
+
CCCFFFFFHHHHHJJJJJJJJJJJJIJJJJJGIJJJJJJJIJJIJJJJJJJIJJJJJJJJJJJGIGHJJJIJJIIJJJHGHHHHFFFFFECEEEEEDDDD
@00E
ACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGT
+
CCCFFFFFHGHHHJJJJJIIJJJJJIHJJJJJJJJJJJJJJJIJJJJJJJJJJIJJJIJIJJGHHHHFFFFFFEDDDDDDDDDDDDDBD@CCDDEDDD9>9
@00F
GGATGAGACAATGAGAGAATTTTTAGAGTTGACAGAACAGAGTCAAAAATTACAGATTCAATTTCAGCAATTACAGGCTAGTGAAACTCTGAGAAACAGC
+
@@@DDFFFHHGFHIJII;EHHHIIJJBHCFHGHIICGGIGEHDGAGIIIIJIGEHJIJIJGGDHGAHIJIFGHIIIIHEEH;B@DFEACCE@AACDDDDB
@00G
CAGGTTTGTCTGCTACCCCCCCTGCCTCATTACCTGGCTCACTAACTAACGTGAAAGCCTTACAGAAATCTCCAGGACCTCAGCGAGAAAGGAAGTCATCT
+
=;=DABDBHHH?FGGIGEHHGHDDHDEFGHFBFGIIIHBGHGDFGG;@EE@EA95CC@DF@DC@CCCACCCCCA>?2???@>?CBBB95?@?<?BCC:>AC
@00H
ATCCAGCCCCCGGCAGGAGAGCACACGCGTGATCCAGCTGATGCCCAGCCCCATCATGCACCCTCTGATCCTGAACCCCCGGCACCCCGTGGATTTCAAAC
+
77:A==@=A88=8=??8;1)0)*079=AAA4;.)=A9=3=A))));;;>=<==35(55=39=899=:;?;=?;+8;;;&9&0&)0(+)))))+8:=(8==?
@00I
TCCAAAAGCCATGAAGAGATTAATGGCAGAGTGCCTCAAAAAGAAAAGAGATGAGAGACCACTCTTTCCCCAAATTCTCGCCTCTATTGAGCTGCTGGCCC
+
@@@FFFFFDDDHDEEIIIIGIJGFFHHIJJJEGCFHIGIHIIJDHIIIIHIIGGCFCHIGEIGHGIJGCHAEFFFFDFEDDDBBCCCDCDDCCDDCDCDDD
@00J
CCTCAAGCTGAGAAAGTTGATGTGATTGCCGGCTCCTCCAAGATGAAGGGCTTCTCGTCCTCAGAGTCGGAGAGCTCCAGTGAGTCCAGCTCCTCTGAC
+
=1144A?DDDDDDI@EC?:?FEEF4A<EEIIID:@;D:BDD90?<DD4BA>CDC7A-;;;?;7?DADDD@@8;;;;::::>:>>A>>AAAAAAA?AAA>
@00K
CCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATG
+
CCCFFFFFHHHGHJJJJJJJJIJJJIJJJJJHIJJJJJJJJJJJJJJJJJJJJJJIJJJJJJIHGGFFFFFEEEEFEFDDDDDDDDDDDDDDDDDDDDDED
@00L
CTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTT
+
CCCFFFFFHHHHHJJJJJJJIJJJJHHIJJJJJJIFIJJJIJJJJJJJIJJJIJJJJJJJJHHHHHHFFFFFFDDDDDBDDBDDDDDDDDDDDEDDD>>@D
@00M
TATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTAC
+
CCCFFFFFHHHHHGIJJJIJGHIJJJJIGIIHIIIIIJIJJIJJJJJJJJJJJJIIJJIJJJJIFIJIHHHHHFFFFFEECDDDDDDDDDDCDDEEDDDDD
@00N
CAGTAAGGTACGGAGTAACTGTCCAAAAGCCATGAAGAGATTAATGGCAGAGTGCCTCAAAAAGAAAAGAGATGAGAGACCACTCTTTCCCCAAATTCTCG
+
CCCFFFFFFFHHHIIJJJJJJJJIIJJIHIJJJJJJJJJJJJJJJJJJJIIJFHIIIJJJJIIJJIIHGFGFFDEDFEDEDDDDDDDDDDDDDDDDDDEDB
@00O
CTCAGCGACACTACCTGGGCCATACAGACTGTGTGAAATGCCTTGCTATACATCCTGACAAAATTAGGATTGCAACTGGACAGATAGCTGGCGTGGATAA
+
CCCFFFFFHHHHHJIJJJJJJJJJIJIIJJJIIHIJJJGJJJJJJIJJJJJJJJJJJIIJJJJIHHHHFHFFFFFFEEEEEDDDDDDDDDDDDDDDDDDD
@00P
AGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACA
+
<@?DDD3AFDHHF@D;CFEGGAHE>DH@??CHGHGDBGGHIIGCAGGFDD9FGIHCGIGA@F@47@CECEEHAB;BBCCCCBBB?=A?55>:5:>C>@C>
@00Q
GTCAAGCAGTAAACATGATGTGTCAGCACACCATGATTTGAATATTGATCAATCACAGTGTAATGAAATGTACATAAATAGTTCTCAGAGAGTAGAATCA
+
C@CFFFFFHHHHHJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJHJIIJJJJJJJJGIJJJJJJJJIIJJJHHHHHHFDFFFEEEE
@00R
CAGCAAGGTACAACTATTCTTCAGTATGCACAGACCTCTGATGGACAGCAGATACTTGTGCCCAGCAATCAGGTGGTCGTACAAACTGCATCAGGAGATAT
+
CCCFFFFFFHHHHJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJ@EHEHFFFDDEEDDDDDDDDDDDDDDDE
@00S
TCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAA
+
C@CFFFFFDHFHHIIJJIJJIJJJJJJIJIJIGIJJIJJIIGGGIJEGIIIJIJEHIIJIJIHHFEFEECEEDDDCCBBDDCA>ACCCDDDDDCDDDDD
@00T
AGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTC
+
@@?BDDDDDB<FHI@@CGGHHHII;:C<BCHGH>CFCEGGC=DDGGBDAHHF.B@=CBGICGI7?CEA;@B?D@36>A@C>;5(55(,,5>(;A?CCCA
@00U
TCCTGGTAGCTGAGGGGCGGAAGATGAAGATTTCGGATTTCGGTTTGTCCCGAGATGTTTATGAAGAGGATTCCTACGTGAAGAGGAGCCAGGGTCGGATT
+
7?=DDDDDHFHHFBEGG>EAF@FHGHIIIGA>DGHFABECCCC=;:?A>CCB8=??>:3>CA@ACC:<ABCC@>@>A9198?CABB8?<8>A?93><>32>
@00V
AACAAGACCACTTATTAGAAGATTATCAGAAAAAGAAAGAAGACTTCACAATGCAAATTAGTTTCTTGCAAGAGAAAATTAAAGTATATGAAATGGAACA
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJHGJJJJJJJJJJJJHHHHHFFFFBCEEEEEEEEDDDDDD
@00W
ATATCAGATCCGAACTACACCTTCAGCTACTTCTCTGCCACAAACTGTGGTGCTGACATCTCCTGTGACTCCCACCTCTCAGACAACTAAGACAGATGACC
+
<@@<DADDFAF322<C3CCF?G>GG@<?4?DGA?<?@9@@>D?9??FBBFD;*/BF;C<FF:=F>.=;@AC)6??=9;;;(>((655>;;;@>:<ABA::A
@00X
ACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCC
+
@@CFFFFFHHGGHIJJJIGFIFHHIJIIGIGGIJIIJJJJIIHGIJJJJJJIHHEHFHFFFFFFECCEEEDCDD@CDDDDDDBDDDDDDDDDDDDDDDD
@00Y
CTCCCAAGCCTGTGAGCAAGATGCGCATGGCCACCCCGCTGCTGATGCAGGCGCTGCCCATGGGAGCCCTGCCCCAGGGGCCCATGCAGAATGCCACCA
+
CCCFFFFFHHHHHJJJJJJJJJJIJJJJJIJJIJJJJJJJJJJJJJJJJJJJGGBFDEDDCDDDDDDDDDDDDDDDDDDBDDDDDDDCDDDCDDDDDDD
@00Z
ATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTT
+
7;=<=A722<<<?+<+<<?>A+3<;AA71*?ABA5AA<AA==?BBBBBA<?*=AA))5=2(=;3>;(.6A)7;>@@@9;6>;,;=;;9=:0)&8:8((+8=
@010
GCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGT
+
@C@FADEEHHHGHEGIIHAHGIIJ>AFDF<EGIHGG@DGHEFGC9B<=90?FGGGGHIC9F@7@DC9CHHEBFCEDEEDDDCCDCDC:@BBCB@CDD@AC+
@011
CAGATGATAGCCGTAATAAATTGTCGAAAATACCTTCAACACCCAAATTAATACCAAAAGTTACCAAAACTGCAGACAAGCATAAAGATGTCATCATCAAC
+
@@@A;DDDHFDDF@EFHIIIIIEAFEHGHIGHIGIIGAGEEHHDGHFHIIIIIDGIIIGH@GGIIIHHHFHFFFFFEEEECBCCCCCCCC>CDDCCACAAC
@012
TACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCT
+
C@CFFFFFHHHHHJJJJJJJJIIIJJIIHIJIIJIIIIJJJJIIIJJJIJJHHHHFFFFEEEDEDDDDDEDDDBDBCDDDBDDDDDDDEDBDDDDDDDDDD
@013
CGGAACTGCCTCCTGAGAAGCTCAAACTGGAGTGGGCATATGGTTATCGAGGAAAGGACTGTAGAGCTAATGTTTACCTTCTTCCGACCGGGGAAATAGTT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJIJFGIJJJJJJJJFHIJJJJJJJJJJJIJJJHIJJHHHHHHFFFFFFFEEEEEEDDDDDDDDDDDDDDDEE
@014
CTTGTCCCGAGATGTTTATGAAGAGGATTCCTACGTGAAGAGGAGCCAGGGTCGGATTCCAGTTAAATGGATGGCAATTGAATCCCTTTTTGATCATA
+
@@@?DDADDAFHCGFHC:CEHIIIIE?CB???@?F?B3D?BBBGFHGHGEGBGFBGEHEEDCBDEEEEDCCCCBCCCCCCCCCCCCCCCCCBBCCCCC
@015
TCATTACCTGGCTCACTAACTAACGTGAAAGCCTTACAGAAATCTCCAGGACCTCAGCGAGAAAGGAAGTCATCTTCATCCTCAGAAGACAGGAATCGAAT
+
CCCFFFFFGHHHHJJJJJJJJJIJHHIIJIGJJGIGHIJJIJFGGIJJJJJJJFIJJJJHJGIJHGGHFFFFFFFDCCDEEEDDDDDDCACDDBDDDDDDD
@016
GTTCATTCCTTCCGATGTTGACAACTATGATGACATCAGAACGGAACTGCCTCCTGAGAAGCTCAAACTGGAGTGGGCATATGGTTATCGAGGAAAGGACT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJIJJJJJJJJJJJIJJGIJIIJIIJHHHHHBDFFDDEECDDDDDDDDDDDDDDDDDDD
@017
TGAGGAACTCTCCAACTTTGCTTACCTCTTGGCCTCTAAACTTAGCCTCTCACCAAGGGAGCATCCCCTCAGTCCTCACCATGCCTCAGGAGGTCAGGGC
+
??@;DD?BCFBHBF@GC<ABHIGIIICF?BAC?GH;G@B??::B:B<?9?9?FDHB9;;;@86CECCEH<E;=@B@DECCCC>ACACCCC:8;??:9?B?
@018
GGAACCTCCTCCTAAAAAGACGAAGAAAAATAATAGCAGCAACAGCAATGTGAGCAAGAAGGAGCCAGCGCCCATGAAGAGCAAGCCCCCTCCCACGTATG
+
CC@DFBEDBHAHHHIGGGHHHIHGIIIIGIIIFIIIIIIIIIIGGIIIIFFHHIIIIGIIGIHFHHFFBCDDDBDDDDDDDCCDDDDDDDBBBDDDDBDDD
@019
CATCAGCAAAGACCTGGAGAAGATGATGGTTAAGAGGAGAGACTACTTGGACCTTGCGGCGTCCACTCCATCTGACTCCCTGATTTATGACGACGGCCTCT
+
??@;::BAD?D:DGF9CG9FGFEEB<E@?11:*?CF=FBFGEFG<9<?BE?DDFIEFFEDBB?6=;;?BBA>AAB@A:A<?@@BBD:B>A><8<5<B3><(
@01A
GTCGTACAAACTGCATCAGGAGATATGCAAACATATCAGATCCGAACTACACCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATGACATCTCCTGTGAC
+
@B@FDFFFGGHHHJJJJJJJIIJJJJJJJIJJIJJJJIJJJJJJJIJJIIGHIJIJIGJJIJJJJJJJJIHHHFFFDFE@CC;AECDDCCCDDDDDDDDED
@01B
GACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCC
+
CCCFFFFFHHHHHJJJJJJJJJJJIJIJIJHHIJJJJJJJJJJIIJJJJJJJHHHHGHFFFFFACEEEEEDDEDDDDDDDDDDCDDDDDDDBBDDDDDDD
@01C
CGCTGTGAGACATGTCTGAGACTCCTGCTCAGTGTAGCATTAAGCAGGAACGAATTTCATATACACCTCCAGAGAGCCCAGTGCCGAGTTACGCTTCCTCG
+
@@@DDDDFBDFDHIIIHIIIHGBCEBGGIIEGICCBGBCEGGGDEFDFDHIII;FHIIECEGGGIGGIEHIE>?EEHFDDD6@@CD?><@CDB=?BDDCDD
@01D
TAACTGTCCAAAAGCCATGAAGAGATTAATGGCAGAGTGCCTCAAAAAGAAAAGAGATGAGAGACCACTCTTTCCCCAAATTCTCGCCTCTATTGAGCTGC
+
@??DDDFFAFHDDGHGHEEHHEHHIIGIIGGIGHG=D9?DGG>GIBGGFGGGFAHGE88=;=3C;5@GCHEEHHCCEDAACCCAC?B@;BC@;5@CCCCCC
@01E
GTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACGGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTAC
+
CB@FFFFFHGHHHJIJJJJJJIJIJJJJJJJJJJJJJIJJJJJJJ6AHIJHHHHHHFFFFFEEEEEEDDCDDDDDDDDDDDDDDDBDDDDDDDDDDDCDDD
@01F
AGGCCGAGCTGCTCACCAACCTGCAGCATGAGCACATTGTCAAGTTCTATGGAGTGTGCGGCGATGGGGACCCCCTCATCATGGTCTTTGAATACATGA
+
C@CFFFFFGHHHHJIJJJJJIIIJGJIJJJJJJJIJJIJIIJJJGHIJFGHIGH@F@FGIBBCB@DDDDDBDDDDDDDDCDDDD>ACCCCDDDEDDDCD
@01G
CAAATCAGCAAACAAATCAAAGCTCATGATGGCAGTGTGTTCACACTTTGTCAGATGAGAAATGGGATGTTATTAACTGGAGGAGGGAAAGACAGAAAAAT
+
CC@FFFDDFHHHHIJJJJJIHIJJJJIIIGIIJJIHHFGGHHGJIIJJJJFHIIJIJIIJJJJJJIGHGEHGIJJHHHHHCDF7ACDDDBDDDDDDDDDDD
@01H
CTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTAT
+
CCCFFFFFHHHHHJJJJIJJJJJJIJJIJJJJJJJJJJJJJBHGJIIJJJJHEFFHHFFFBDBCCCEDDDCCDDDDCDCCDDDDDBBDDDDDDDDDDDDDD
@01I
ATTTACTCGTATTGTTCCTGTTCTTTCAAAACACTTCTATTCCTAACTTAGCTAACTTCACTCATTTAGCTTACAAGTTAAAATGTAATAATTTAGGTAAT
+
-(5(<):6(2-.==4)))3);9?)<))2)293(8)))1)2).6=:>(:7.).9<):)))..)))).)/..)).):3.)8))))).)).))..))))(.6(.
@01J
CAGAAATCTCCAGGACCTCAGCGAGAAAGGAAGTCATCTTCATCCTCAGAAGACAGGAATCGAATGAAAACACTTGGTAGACGGGACTCGAGTGATGATTG
+
CCCFFFFFHHHHHJJJIJJJJJIJJIJJJJJJIJJJJIJJJJJJJJJJJIIJIJJJJJIJJIJIJHHHHHHFFFFFEAEECEDDDDDDDD<>:?CDDDDED
@01K
CTGAGAACTTCCTGATCTCTCTCGCTGTGAGACATGTCTGAGACTCCTGCTCAGTGTAGCATTAAGCAGGAACGAATTTCATATACACCTCCAGAGAGCCC
+
CCCFFFFFHGHHHJIIJJJJJIJIJJJHHGIGIIGIHIJJJJGJIJJJIJJIJJHHIGIHIIJIIJICFHIIJGHEHFFFFFDEEEEEDEDDDDDDDDDDB
@01L
CACAAATTCGAGCATCACCTTCTCCCCAGCCCTCTTCACAACCTCTCCAAATACACAGACAAACTCCAGAAAGCAAGAATGCTACTCCCACCAAAAGCAT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJHHHHHFFFFFEEEEEDDDDDDDDDDDDDDDDDDDD
@01M
GGCAGTACTCAGCAAGGTACAACTATTCTTCAGTATGCACAGACCTCTGATGGACAGCAGATACTTGTGCCCAGCAATCAGGTGGTCGTACAAACTGCATC
+
+==AA3+?C<<@<=?3723?37+3<A?+?<4A4?<AABBB9)*10=?*=**0==3=A9=;;>B<>BB==)=9;257A3=AA>;>='.9;;2(;;(,:>(,(
@01N
CCGATCCTCATCAGCTCCCAATGTGCATATAAACACAATAGAACCTGTCAATATTGATGACTTGATTAGAGACCAAGGATTTCGTGGTGATGGAGGATCA
+
C@CFFFFFHHHHHIIJJJJJJIJHIIJIJJJIIIIJJIIJJJJJJGIIHJICFHIIJIJJJJJGHGGJJGGHIIJGHHEFFFFFDDD;@CDDDCDDDDDD
@01O
ATCCTTGTAGCTTACCCAGAGCAATGACAGGAGAAAGGCTTGGGGGACAGGGGGAACCTGGGCACACCTTGCATGCCAGCCTGAGAGGGGGCACCGGGGGG
+
+11=?DD4ADFF4CD@FFEBFEIF?CHEFI?GEFFF?C?3?@BD6(6'(5C(:?'3;?,;?;9<<9(,:((5>(4:>3(22313(+>()&&&0(()0.&05
@01P
CTAGAGGGAAAGCGAGAGGGAGACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGC
+
@@@DDDDDH?FHAD1@:EFHGHIIGIIBFHII=GCG;FGE@@EBEE=6?A@=@?@CCCCCC98;5>7@?9>>;CCA@CCCAACCC@C:A92<>@CCC@BB
@01Q
CGCAGCCCAAATCCCCATCCAGCACGCCAGTGTCCCCACTGCATCATGCATCTCCAAACTCAACTCATACACCGAAACCTGACCGGGCCTTCCCAGCTCAC
+
CCCFFFFFHHGHHJJJIJJJJJJJJGHIIJIIHIIJIJJJIJIJJJJIIIJJIIJJJJJIIJHHHHHGFFFFDDDDDDDDDDDDDDDDDDDDDDDDDDDCD
@01R
TCAGAAGCCACAAGTGGGAATGAGGCCCTCCAACCCCCCCACACCATCCAGCACGCCAGTGTCCCCACTGCATCATGCATCTCCAAACTCAACTCATACAC
+
CCCFFFFFHHHHHJGIIJIJIJJJIJJJIJJJJJJJJJJJIJIJHHHHFFFFFE9ADDDDDEEDDDDDDDCDDDDDDDDDDCDDDDDDCDDDDDDDDDDDD
@01S
CCTCACTCATCAACAGCAGCTTGAAGAACAAGACCACTTATTAGAAGATTATCAGAAAAAGAAAGAAGACTTCACAATGCAAATTAGTTTCTTGCAAG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJIJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJIIJHHHHHHFFFFFFEEEDECEEEDDDDDDD
@01T
CAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTTATGGGCAGG
+
@??DDDADFDFHFII<<C::<<BA4AA9FFHGII@DF>F9BFGAFG6?F;88CH7=CGDDHG>B:4==>6=@??88?55>>@C<:<?><B03444@@B<>B
@01U
CTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACC
+
@?=?BDDDD3CABGG@FEB<<FGFE3CHEFFI?FF?)09??FAFFFF<5=A@DE:DDEB,9.;(;>>33=;;@A@@3::;;A>BA(5+3:4>>>AADB:AB
@01V
GTTGAATGTGACAGCACCTACACCTCAGCAGTTACAAGCCTTCAAAAATGAAGTAGGAGTACTCAGGAAAACACGACATGTGAATATCCTACTCTTCATGG
+
CCCFFFFFHHHHHJIIJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJHJJJJJHIJIJJJJIJJJIIHHFFCDEEEEEEEEFEEDDDDDDDEEDD
@01W
GTACAATGTCAGTGCCTATGATCAGAAGCCACAAGTGGGAATGAGGCCCTCCAACCCCCCCACACCATCCAGCACACCAGTGTCCCCACTGCATCATGCAT
+
@@@DADDDH<BF?@AA?CAA?<FDHIIGC;?GD8?11?3?DGDDBAFHDGIIC?FA:;;8/3=A1;?5>BCC?<<(9?8@4@:ACCB991@A>C:>::3@C
@01X
CCGCCACTGAAGGGGAGCTTCCCGGAGAACCTGAGACACCTTAAGAACACCATGGAGACCATAGACTGGAAGGTCTTTGAGAGCTGGATGCACC
+
@@@DDFFFHHFHFII>FIIIJJJJIHHGDHIJIIIJGIIJJJJJJGIIJJJHHGHGEDEECEEEEEDDDDDCD>ACCDACBBDBCCCBDD@CCA
@01Y
CTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHHHHFFFFFFECDDDDDDDDDDBCDDDEDEDDDDDDDDD
@01Z
TAATTACATGCGGTAAATCTCGTATTTTCTTCTGGACCTGGAGCGGCAATTCACTAACAAGAAAACAGGGAATTTTTGGGAAATATGAAAAGCCAAAATTT
+
1??+=DDDD?DA1@E1?E<,A+2<FEI@>BDEDBD>DB@>@BDD066;ADE9CC7@CDCD=@@@DA=@?5=;?AAAA?/3<>?A4>A:AA33<19<>1>A:
@020
GTGTCCAGAGGACCCCCAGGCCATCCGTGGATAATGTGCACCATAACCCTCCCACCATTGAACTGTTGCACCGCTCCAGGTCACCTATCACGACAAATCAC
+
CC@DDFFFHHHGFDGJIIDBEIGGEGGHGICEHGJGIIGIHIJGIJFID>FHIGGIJIHAE?EFFDFBC>CCABB?BD<C:@CCCCCDDCCDDDDDDDCDC
@021
CTCCTACATGCCTTCCTACCATGCCCACCAGCAGAAGGTGAACTTTGTCCCTCCCCATCCATCCTCCATGCCTGTCACTTCCT
+
CCCFFFFFHHFFFJGHGHHHIIIJIJJJGGHDGHGEFG?FFGHGDGGHIHCGHIIGAFHIIH@@EAEHIHHCEECFEFDEECE
@022
CTTCAGCTCTGGCAGTTTTTGGTAGCTCTTCTGGATGACCCTTCAAATTCTCATTTTATTGCCTGGACTGGTCGAGGCATGGAATTTAAACTGATTGAGCC
+
CCCDFFFFHHHHGJIGIJJJJJFHIIJIIJJJJJGIIJGIIIIJIJJJJHIJJJIJIIJGIJJJJIDHGIJEEHEEFACCDDDDDDCDEDCDDACCCCDDD
@023
GTGTGATTCCCTGTGGAGGCACAGTTGCGGCAGCTGCCCTAGAAAAGAGAAACTATTGCAGCTTGCCAGGACCTTTGAGGGCCAACAGCCCACCCTTGAGG
+
@B@DFFFFHHHGHIHIJJIIJJJJGIJJJJJJJJIIJGGIIJIJGJJGGCGIGGGGIGEEFEDEC?DCCDABB?DD>@BDD@DDDBB@?BDDBDBACCCCD
@024
AGTTAATGGGGACAGTCGAAGAACTTCAGAAGAGAAATCATAAAGACAGCCAGTTCGAAACTGATATAGTACAACGAATGGAACAAGAAACACAAAGAA
+
:??DFDFFGGHHGJBIIIEGEEEGGI@FGGGIICIICGAHEIIJJG@HEG@CBGGIGIJJJGIEAEFE>7AADFFFDABECDC>BCA?CCDDBDDDDDD
@025
TTATCATGGGGACTGAGGATGCCTCCTCCTTGCCTGAAGCCAGTCAAGAGGCAGGGAGCAGAGGCAATTCCTTTTCTCCTCTGTTGGAAACCATAGAACCT
+
CCCFFFFFHHHHHIJJIJGGIIJJJIJIIJIJJIGIIJIIJIJIGGIIHIJBGHIJ=EGEHAHBEBFEDEEEEEDDDDDDDCDDDDDDDDDDDDDCCDCDC
@026
AAAAAAGTAGAAAACTCAAATAAAGAAGAAATACAGGAAAAGGAGACAATCATTGAAGAATTAAACACAAAAATAATAGAAGAAGAAAAGAAAACTCTTG
+
CCCFFFFDHHHHHJJJJJJJJJJJIIJJJJJIJJJJJIJIIJJIJJJJIJJIJJJJJJJJJIJJJJIHHHHFFFFFEEEEEEDDDDDDDDDDDDDDDDDD
@027
GGAACAGTCTACAAGGGAAAGTGGCATGGTGATGTGGCAGTGAAAATGTTGAATGTGACAGCACCTACACCTCAGCAGTTACAAGCCTTCAAAAATGAAGT
+
@?<DADDBFHDFHIIIGECHC+AFEHEHI?E9E?:?FG@A:BFHIEBG9??8D?<99/.8=FHAF@=>@DHICCC@??@B@:;;66?>@C@ACCB?@CCC5
@028
CAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCC
+
CCCFFFFFHHHHHJJJIJJJJIJJJJJJJJJJIJJJJJJJJJJJJJJJIIGJJJJJJJHHHHEFFFFFFEEEEEEDDDDDDDDDDDDDDDDDDDDDDDDDD
@029
GACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCC
+
@<BBFFFFHFHHGJJIIJIIIIJJJJIIGIHHIIIEIIGGIJJJIJIIIIIJEHHHHHFFFDF@CECEEDDDDCCCCCDDCDD>ACDCCBDDDDDCDDDD
@02A
CTAGAGGGAAAGCGAGAGGGAGACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGC
+
@B@FFFFFDHHHHIIJGHIIHIHIIJEGHHIIGIIIGIEGIHHAEFEFFDADDDBDDDDDDDDDDDDDBD@DDDCDDEEDDDCDDEDDDDDDDDDDDDDB
@02B
GCCAATTTACTGGAGCAGGGATGACGTAGCCCAGTGGCTCAAGTGGGCTGAAAATGAGTTTTCTTTAAGGCCAATTGACAGCAACACGTTTGAAATGAATG
+
CCCFFFFFHHHHHJJJJJJJIJJJJJJJJJJJJJJJJJIJJJJHIJJJJIJJJJJJIHFHIJIJJJHHHHHFFFFFEEEEEDDDDDDDDDDDDDDDDDDED
@02C
CAGATGTATATGCATTTGGAATTGTTCTGTATGAATTGATGACTGGACAGTTACCTTATTCAAACATCAACAACAGGGACCAGATAATTTTTATGGTGGG
+
C@CFFFBDHHFHHIIIGJGIJJJJGDGIIGEIJIJJJIIIIJIJDGIIJIIBHIJJIIJIIJJJIIIGJJIJJJGHJJJHHHGFFFFFFFEECEEECCDB
@02D
GGCGGAGCTGTGCGAGAGCCTCCTCACTTGGATCCAGACATTTAATGTGGATGCACCATGCCAGACCGTGGAAGATTTAACGAATGGGGTTGTGATGGCCC
+
@<@DDFFFHBFFBEFGGGCHGGHGGGEAFHIFEGGIGIIIIIIIEII=FG>=FHGIIIHHCEEHFFFD8=B?CD9@CCCD@B??8CCBD<@B>BAAC@<??
@02E
CTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTTATGGGC
+
C@CFFFFFHHHHHJIIJJAHIJJJGIJIJJJJJJIJIJJJIJJJJJJJJBGGCGHHIDHGIFHHHHHFDDDCDBD@DDDDDCCCCCDDDD(50<CACDDDA
@02F
ACCAGATAGCAGCTACCCCATGGACCACAGATTTCGCCGCCAGCTTTCTGAACCCTGTAACTCCTTTCCTCCTTTGCCGACGATGCCAAGGGAAGGACGTC
+
@@@DDAFFHHFHFGHIIBGGGFIHIJGIJJGIIGHJIIEGGGHIIJJFIIGGIIIFCEEEHFDFFFFDDECCEDDCDCB=@BB@DBCDCBBDBABB<AB>B
@02G
TATCAGATCCGAACTACACCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATGACATCTCCTGTGACTCTCACCTCTCAGACAACTAAGACAGATGACCC
+
CCCFFFFFHHGHHJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJIHHIBFGIJJJIJJJJJIIIJJJIGIHHHGFDFFFFFEEEDEDDDDDDDDDDDDDD
@02H
CTACAACCCCACGTCAGAGTGTGGGATTCTGTTACTCTATCCACACTGCAGATTATTGGACTTGGCACTTTTGAGCGTGGAGTAGGATGCCTGGATTTTTC
+
?;?DDD?DHHAFHEEFBGEAF@BF:ECFHGGHICBBGCEHIIGIHFEAD=C=FHIIIEHIII<DC@HE@EEH>BB@ACB@1;,5:C>AA?CCC<@@CCCC>
@02I
CCAACAGATGCAAATACCATAATTACATGCGGTAAATCTCATATTTTCTTCTGGACCTGGAGCGGCAATTCACTAACAAGAAAACAGGGAATTTTTGGGA
+
?;?DDD>DD??BB<EAEGEDHEH,,<<9<CF@FEEHEDGGDAC>>F99?<@D939?DBDC;BD<6<,'7?(6;@;@CCC?=A<C(,9A?852:@C>.&5A
@02J
CACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGCTATTCCT
+
?<?DDD;:DADABFBEFGD<?<A<A?AEF@G?GBFFFFDFFGBDEFFFIFFIFIIGEFFFGICEIDIIEFFFDDDDD>@CAABBBBBBBBBBBBBBBBEEB
@02K
CTCTGAGAAACAGCACTCATAGTAGCACAGCTGCAGACTTACTACAAGCCAAACAACAGATCCTCACTCATCAACAGCAGCTTGAAGAACAAGACCACTT
+
CCCFFFFFFHHHHIJJJJJIJJJGHIJIJJJJIJJJIIJJJJJIJJJJJJJJJJJJFIIJHGIJIJJJJIJHHHHHFFFFFEEEEEDDDDDDDDDDDDDD
@02L
CCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCT
+
CCCFFFFFHHHHHJJJJJJIJIJJIJJFHIJJJJJJIIJJJJJJJIIHIHJIEHGHGGGIJJJJJJHHHHHFFFCFEEDDEEDDDDDDDDDDDDDDDDDD
@02M
CGCAGCGCGAAGTCAACTTGAAACCTACAAGAGACAGGAGGATCCAAAGTGGGAATTCCCTCGGAAGAACTTGGTTCTTGGAAAAACTCTAGGAGAAGGCG
+
@@@FFFFFAFHAHGHIIGDHIIII@?GHHGII@FHGHCB;@GHIIDC47)=CHHFB@CDEEECBBB>9CCCC@@C<@::>>ACCCCB@CCCCCCCBCCCB@
@02N
GACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTG
+
@@@FDFFFGHHFHGJGIJIGGIHJIGGDDFEGIJJJIIJFGHGIJDGHGIIC>FD=FGDHIFFDDDDDDDDDCDDBBDDDDDDDDDDD5<CDDDDDDDD@C
@02O
CGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCG
+
@B@FFFFFHHHHHJJJJFHHEGIHGIJJGHIIIJJGIJJJJGGIJHHHFFFFEEEEDEEDDDDCCDDDDDDDDDDBBDDDDDDDDDDDDDDCDEDDDDDDB
@02P
ACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAAC
+
CCCFFFFFHHHGHJIJJJJJIFICHIDDHJDHGEIJJJJJJJJJJJIJJJJGIJIJIIJIHHHHGHFFFFFFCCCDBCDDDCDDDDCDCDEDEDD@CCDDD
@02Q
CCCCCTCCCACGTATGAGTCGGAGGAAGAGGACAAGTGCAAGCCTATGTCCTATGAGGAGAAGCGGCAGCTCAGCTTGGACATCAACAAGCTCCCCGGCG
+
CCCFFFFFHHHHFHJJJJHIJJIJJJJJJJJIJJJJHJJJJJJJJJJJJJJJIJJJJHHHHFFFFDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDD
@02R
CGATGAGGTGGCCAGGCGCTGGGGCGAGCGGAAAAGCAAGCCCAACATGAATTACGACAAGCTGAGCCGGGCCCTCCGTTATTACTATGATAAAAACATT
+
CCCFFFFFHHGHHIJJJJJJJJIIFIJJIIGABEEDCDEEDDDDDDBDDCDEEDDDDDDDDDDCDBDDDDDBDBDDDDDDDDDEDDDEDCEECDDDDBDC
@02S
AGAAAAGAAAACTCTTGAGCTAAAGGATAAATTAACAACTGCTGATAAATTACTAGGAGAATTACAAGAACAGATTGTGCAAAAGAACCAAGAAATAAAA
+
CCCFFFFFHHGHHJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJIJJJJIIJJJJJJIIJJJJJJHHHHFHFFFFFEDDEDDBCDDDDDD
@02T
CACATACCAACGGCGAGGATCACTTCAGCTCTGGCAGTTTTTGGTAGCTCTTCTGGATGACCCTTCAAATTCTCATTTTATTGCCTGGACTGGTCGAGGC
+
CCCFFFFFHHHHHJJJJJJIJJJJJJJJJJJJJJJJJGIJJJJJHHHHHHHHFFFFFFEEEEEDDDDDDDDDDDEEEFEEDDCDDCDDBDDBDCDDDDDD
@02U
GTAACTCCTTTCCTCCTTTGCCGACGATGCCAAGGGAAGGACGTCCTATGTACCAACGCCAGATGTCTGAGCCAAACATCCCCTTCCCACCACAAGGCTTT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJIJJJJJJJJJJFIIGIJJJJJJJJJHHHHFDDDDDDDDEDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDD
@02V
CACAGATGGAGTACAGGGACTTCAGACATTAACCATGACAAATTCAGGCAGTACTCAGCAAGGTACAACTATTCTTCAGTATGCACAGACCTCTGATGGAC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJEIIJJJJJJJJJ@HIJJJJJJJIHHHHHHHFFFFFFEEEDEDDDDEDDDD
@02W
CACCCACTTAAGTGACCTGATTAAAGTGGGAAGAATTATGGCCGCATACCTCCTTTTGGGCAATGGCAAGGAATAGGAGCGGCATACAGGCCAGAGCTGC
+
(((2@81<>6=)2)2@89)))).)))))2(=)=(..)8)))()((7(().))(.)8)/3/(.-).)6))((6(.3((((,,375-((((+(++((+((+(
@02X
CCCCCGGCACTCCGTGGATTTCAAACAGTCCAGGCTCTCCGAGGACGGGCTGCATAGGGAAGGGAAGCCCATCAACCTCTCTCATCGGGAAGACCTGGCTT
+
CCCFFFFFHHHHHJIJJJJJJJJJJJJJJJJJJJJJIJIJJJJJJJHFFDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDCDDEDDDDDDDDDDDDDDDD
@02Y
AGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCAC
+
@C@DDFFFHHFHHIJIIIFFGHGIGHGIICGIIJIJJIEGIJGGGHIJIGIIIJJHIGEEGGIFGHGFFFEFCEDEEDDDEDDCDDDCDDDDDDDDEDBDD
@02Z
CTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTAC
+
C@CFFFFFFFFDHIJJJJJJIJIJIIJIJIIIIJJJIJJJIJIIIIJFIIJIGEHHHHFFFFFFDEECCDDEDDDDDDDEDDDDDDD>>CDDDDDDDDDDD
@030
GTTTCTGCATCTGAATCCAGAAAGGAACTAGAATTAAAACATGAAGCAGAAGTTACAAATTACAAGATAAAACTTGAAATGTTAGAAAAAGAAAAGAATGC
+
B@CFFFFFHHHHHJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJHIJJJJJJJJIJJIIJIJJJJJJIIJHGHHFGGFFFFFDDEEDDDDDDD
@031
AAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTAC
+
CCCFFFFFHHHHHIJJJJJJJJJJIJJIJJJIJJJJJJJJJJJJJFHIJJJJJHHHHFFFFDEEEDDDDDDDDDDDDDCCDDEDDDDEDDEDDDDDDDACD
@032
CGGGACATTGCCTGTGGCTGTCAGTATTTGGAGGAAAACCACTTCATCCACCGAGACATTGCTGCCAGAAACTGCCTCTTGACCTGTCCAGGCCCTGGA
+
CCCFFFFFHGGHHIHGIIJJIJJJEHIIJJIIJJGIJJJJJJJJJJIIIIJIJIJJJJIIIIHFFHFFEFFFEEDECEDDDCCDDCCDDCCCBDDBDD<
@033
GGCCAACCAAGCCCTCGAGCAGTTATTCCCATGTCCTGTATAACCAATGGAAGTGGTGCAAACAGAAAACCAAGTCATACCAGTGCTGTCTCAATTGCAGG
+
CCCFFFFFHHHHHJJJJJJJJJHIIJJJJJIJJJJJJJJJJJJJJJJJIJHGICFI=FHHIHGIIHHHHHFFFECEDEEEDDDDDDEDCDDDEDDEDDDDD
@034
CTGCTGAAGACAGACATGGAACGTCACATCAACGAGGAGGACACAGTGCCTCTTTCTCACTTTGATGAGAGCATGGCCTACATGCCGGAAGGGGGCTGCTG
+
CCCFFFFFHHHGHJJJJJJIJJIHJIJJJJJJIJGHIFIJJJIJJJJIGGJIIJJIJIGGIJHHFHHHHFFFFFEEDEEDDDDDDDDDDDDDDDDDDDDDD
@035
GAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGAC
+
@CCDFDDDD?C@HHGHDGGGIGIGIFCFCDBGEHFGGFHGEHGCEF@@AHGHEAAHF;@@@>BAC@CAC>CC8=BBDDDDDDDBDCCDCB:A@@C>CDDD?
@036
AATGTATCGGGAAGGACCCACATACCAACGGCGAGGATCACTTCAGCTCTGGCAGTTTTTGGTAGCTCTTCTGGATGACCCTTCAAATTCTCATTTTATTG
+
???DDDADFHFHHJEGGHGHIGGDGGHEGIGGIGBAECEEEHHHDDBC;BCC>AAAC;A;@D5@C@>CACCDDDC>ACCDDDDCCDDCDCDCDACDDCDCD
@037
CGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCG
+
CCCFFFFFHHHHHJJJJJJJHHIGIJJIJIJJJJJJJJJJJJJJJHHHFFFFEEEEEEEDDDEDDDDDDDDDDDDDDDDDDDDDDDDDDDBCDEDDDDDDD
@038
AATTCTATAGGGTCAGTGCCTGGGGTGGGTTAGGGAGCAAGTGGGAATCATTGGTTTGAAGGGTGGGGGTACTGGAGGGGGGGGGGGGGGTGGGAGGAACG
+
(-(-()2)))).))..)))).)(3((1<;(-0()(9((()))))6().)).)).>((().))'(,',3'&)(((+(+(58585&)&)&0&&)&&((&(+(&
@039
GATAAGTTGGCATGGTCGAGACTTTTGTTGTTATCGAGTATGTATTTTGGCTTCTGTCTTAGTGCTGGAATACTCGGGCTTTGGCTTGGCCCAGAATTGGC
+
11+2<+2@?<+27A+221<<7?++2221:)1)1?<5))00000=<7*00.==589)/===)=)/>;AB9=).))),(,',5((((((,5955(((((+8(3
@03A
GGATCCAGAAACAAGCCCACCAGCTTGTGGAACCCAACGTACGGCTCCTGGTTTACAGAGAAACCCACCAAAAAGAATAATCCTATAGCAAAGAAGGAGCC
+
CCCFFFFFHHHHHJJJJJJJJJIJJJIHEGIJJJJJJJIDHHHJJGIJJIJIHIHHHHGEFFFFFDDDDDDDDDDDDDDDCCDDDDDDCDDDDDDDDDDDB
@03B
CCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATAC
+
CCCFFFFFHHHHGGIJJJJJIJIHIIJIEHGHEGIJJJJGJGGGJJIJJJIIIJJGICEHFHHFFFFEECEECDDDDDDDCCDDDDDDDDDDDDDDACCC
@03C
TCCAGGAGCAGCTCAAAGCCGTGCACGAGCAGCTTGCAGCCCTCTCTCAGCCCCAGCAGAACAAACCAAAGAAAAAGGAGAAAGACAAGAAGGAAAAGAA
+
CCCFFFFFHHHHHJJJJJJJJHIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHHFFFFEEDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDD
@03D
CCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTGAGTTGCTAAGAGAGAAAACCAAAT
+
C@CFFFFDFDHHHIIGIBGIJJIGGGHGIGEGIIJJGHHGHJJJ?FBGIIJIIFIJEIDHBHGIGFHDFCDEDCB;@ACCACCDEDDDCCBDCCDCDDDDC
@03E
CTTTGGAGCCGCATCACAATACTGGACCTCCCCCACGGGGGGAATCTACCCCAACCCCAACGTCCCCCGCCATCCTAACACCCACGTGCCTTCACACTT
+
@@@FFFDFHHFHHIIJJJGJIIEGGHEHJJJJJEEIGDEA<66@AC>CCABDB@BDDDBDDD?A?BDDDDBBDDDCDD<ACDDDD@<?BBCDDCCDCDD
@03F
CTTCCTGTACCAGCAGCAGGGCCGGCTGGACAAACTGACAGTCACCTCCCAGAACCTGCAGCTGGAGAACCTGCGCATGAAGCTTCCCAAGCCTCCCAAGC
+
@?=BDAB+?FDD>F;:E9:BFE;E6@DHGC2DHCDBF*==BC@FHD<FEHE>EE367@;).;6;;>@;@C@39?==@3<A@::ACCCCCC8<B@C@<?>8?
@03G
CTTTACCCTTCCTGATGTGAACCTTATTGGGGAGCATTCTGATGCAGCAGAGCTTGGAAGGATGCTTCAGCTCATCTTAGGCTGTGCTGTGAACTGTGAAC
+
;?@BDDDDDBB?FIBHGEHHIEHDBCHIIFIIF>GDHDE@FCHEDG?FGGC=F@<F;@@@FH>>E=??C=;=?CFDFB3@CCEC5?C@C@3>CCA:@>CCA
@03H
CTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCT
+
CCCFFFFFHHHHHJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHHHFFDDDDDDEEEDDEDEDDDDDDDDDDDDD
@03I
TTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAAC
+
?@@DD>BDBAF>?BC?CFA<?FE4EF@><FGEE@DBFDF<@FFECECFE9@;=C;F=;7)6@AFCEE?>@C@@B>@A@BB>?BBB??5>>>>>@ABBBABA
@03J
GATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHHHHHFFFFFDDDCDDDDDDDDCDDDEDEDDDDDDDDDDD
@03K
CCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJIJJJJJJJJJIJJJJJIIJJIJJIJJJIJJJJHHHFFFFFEEEEEEEDDDDDDDDDDDDDDDDADDDDED
@03L
CTTATTCAAACATCAACAACAGGGACCAGATAATTTTTATGGTGGGACGAGGATACCTGTCTCCAGATCTCAGTAAGGTACGGAGTAACTGTCCAAAAGCC
+
CCCFFFFFHHHGHGJJIHIJGIJJGIJJJJIIIIIIJJIJJI?FHHFH@A@EGEHAGEFHFFHFFFFFFEEEE@CEDD;@ABDBD1>AAD:CCDDDDDCDD
@03M
CAAGGCTTTAAGCAGGAGTACCACGACCCAGTGTATGAACACAACACCATGGTTGGCAGTGCGGCCAGCCAAAGCTTTCCCCCTCCTCTGATGATTAAAC
+
CCCFFFFFHFHHHJJJJJFFHHIIJIJJJJJFHGIJJJJIJGGJJJJJJJIJFHIJGGFAHGFFCDDDBDDDDDDDDDDDDDDBDDDDDDDECEEDEDDD
@03N
GTGAAAATGAAAAGTTCTGTCTTTGATGAAGACAAAACTTTTGTAGCAGAAACATTGGAAATGGGTGAGGTTGTTGAAAAGGATACAACAGAACTCATGG
+
B@BDFFFFHHHHHJIJJJJJJJJJJJJJJJJIJJJJJJJJJJJFIJJJJJJJJJJJJJIJJJJJJFHIIJDHIHHHHHHHFFFFEEEEDDDDDDDDDDDD
@03O
GCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTAT
+
@CCFFFFDHHHHHJJJJJJJJJIJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJIHHHHHHFFFFFEECDEDDDDDDDDDDDDDDDD
@03P
CTCAACCAAGTGAAAATGATAAACTTCAGAAAGAACTCAATGTACTTAAATCAGAACAGAATGATTTAAGGCTACAGATGGAAGCCCAACGCATTTGCCTC
+
CCCFFFFFHHFHGJJJJIFGIJJJIJJJJJJJJJJGIJJIJJIIIJJJJJJJJJJJIJJJIIIIGJJJJJJJJJJJJJIHHHHGFFFFDDDDDDDDEDDDD
@03Q
ATTAATGGCAGAGTGCCTCAAAAAGAAAAGAGATGAGAGACCACTCTTTCCCCAAATTCTCGCCTCTATTGAGCTGCTGGCCCGCTCATTGCCAAAAATTC
+
CCCFFFFFHHHHHFHJJJJJJIJJJJJJJJCHGGJJJJJJJIIJJJJJJJJJJJJJJJIJIJJIGHHHHFFDDEFEDEEDDDDD@DDDDEDDDDDDDDDD>
@03R
CGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCT
+
CCCFFFFFHHHHHJJJJJJJIJHIJJJJJJJHIIJJJJJJIJJJJIIJJJJJJIJJJJJJJJJJIIHHGHHHFFFFDDDDDDDDDDDDDDDDDDDDDDDDD
@03S
TTATGATCAGAGCAGATACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGCAGCTTTGGTCAACAAAGCAGCTATGGGCAGCAGC
+
;;;5(:8@:8<>>9=)));8=???))9=??1)=5))).)911=>95=55531:;>???9=6>7;>5)8)(.((60.:;1;:;707;88;07(87;<5<(88
@03T
GTAAACTTAAAGCACTTAATGAAGAGCTTCATTTGCAAAGAATAAATCCAACTACAGTGAAAATGAAAAGTTCTGTCTTTGATGAAGACAAAACTTTTGT
+
@B@FFFFFHHHHHJJJJJJJJJJIJJJJJJJJJJJJJJJIIIJJJJIJIJIIIJJJJGIJJIIJGIJJJJIHIIIJJJIJFFHGHHEDCDFFDEEEEEDD
@03U
CCCAACCCCAACGTCCCCCGCCATCCTAACACCCACGTGCCTTCACACTTAGGCAGCTACTACTAGAAGCTTACTCATCAGTGGCCTTCTAGCTGAAGCCC
+
@<@D?D@AF=FBHD=<C;FFHFEGHHGEGHICHHGHG@FHADGGIFFHAC>DCEBDB@CCCCCCCAACCCCCC@3:ACC@C:@C??@CCCCCCCCCC:>@?
@03V
CAACGGTTTATGGTGCACTACTCATCACCGTTAACCAGGAACCCCTCCGTGAAAATATCCCAAACGGGTTCTTGAACTTGCAAAGGGTGGAAAAGGTTGG
+
8(0(:((:0<4>)).)))..;;)@)@24)(:?(():)(((.(0(<('--((((.8.=?).<?0=('9'9(((7((-:((,(5(,(7((()((((+++:(&
@03W
TGTGCAGTCTTTGCCAACAAAAAAAATTACCANNNNNNNNNNNCCAGATGAGCACNTCATTCTAAAGACCACATTTGAGGATCTTATTCAGCGCTGCCTTT
+
@@C;BDBBFCFFFIIEGFHIIIIIIIEAHGHI###########-.;DHIIEFGHC#,5;?=@ACEC>C=CCB@CCA@CBCC?CC:ACEACCC5<?BBBCCC
@03X
TATCTACACCACGCAAAGTGATGTATGGTCTTTTGGTGTCCTGCTGTGGGAGATCGTGACCCTAGGGGGAAACCCCTATCCTGGGATTCCTCCTGAGCGGC
+
;8::DBAD:?+:2?<)@3<++2+2?C<;*1?CEDDD)6BD?DDDD9*0)(.<A=;68@;;@;A;>?==?83=59=?(8:3(4>9(2((+:4:39>:3:55&
@03Y
CTCTGATGGACAGCAGATACTTGTGCCCAGCAATCAGGTGGTCGTACAAACTGCATCAGGAGATATGCAAACATATCAGATCCGAACTACACCTTCAGCT
+
CCCFFFFFHHHHHIJJJJJJJJJIJJJJJJJJJJJJIJCGHGIGIJJJJJJJJJJJJJJJJJJJJJJHHHHHFFFFFFFEEEEDDDDDDDDDDDDDDDDD
@03Z
CAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTC
+
<7;DDDDDFBDBHBHGGFBFGEHC<GBE;?:?DGF?FEC:DGEBDCHC???B?FGGGBGCHEGCDGAECE>C@DEBA@:>AACA;@CA@?CCCBCCCBBC?
@040
GGGATGGCGGCCAACGAGCCTGCGGCCGAGGCAGGCGCCGACCAGGGCAAGGGCGCCGGGCCCAAGCTCCGCATCCGCGAGGGTTCGGTGCCGGGGCGGG
+
;;9=(2-)(05(((-:=/(0):(7;?'-'-5,,,'''''')00&(()((+2(2(&&5&&)&&&((+(+3()&&)&(&(&))&&((+&5((&())09&&&)
@041
GAACCCTGTAACTCCTTTCCTCCTTTGCCGACGATGCCAAGGGAAGGACGTCCTATGTACCAACGCCAGATGTCTGAGCCAAACATCCCCTTCCCACCAC
+
CC@DFFFFHHHHHGIJIIJJICFHHIIIGD<CDG?FFHIJIIIHGGJJFIIIHGEEHFEDBDDCAADDD=ACECDDDDCCCDC@BCCCDDDBDDDDD@BD
@042
CTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCT
+
BBCFFDDFHHGHGJGJJJJIIJJJFHEHJJJIJJJJJJJJJGGIGGHGGCHGIEHGGHJIGIGIIFIHHFCHFFDCBDDC@CDCCDCDDDDDCDDDDDDDC
@043
CTTACAGTTGGCAAGTCCAGGCACAGATGGAGTACAGGGACTTCAGACATTAACCATGACAAATTCAGGCAGTACTCAGCAAGGTACAACTATTCTTCAGT
+
CCCFFDFDFHGHGJJFHHIIGIHJIJJGJJJI@GEIIJIGIJIJJJJJJIJJJJJIJIIGIJJJJJJJIJJIEHHGFHDDFFFC>C>AEDCDDEEEEDDD>
@044
AGCATGGCCTACATGCCGGAAGGGGGCTGCTGCAACCCCCACCCCTACAACGAAGGCTACGTGTACTAACACAAGTGACAGTCAAGCAGGGCGTTTTTGCG
+
+:1??AAAA3=;AB?AA)<1?C7A=)=.<733=>7=AAAA8<AA===>>>(,;=='5,93;,55;(38(3:3;((++(53:8::??:9<<=<=&0&9(9=5
@045
GGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTC
+
@@@FFFFFHHHHHJIJJJJIIJJJGGHCGDEHEHGIIJJJIGIIGGIGGIGIIJJJIIIJJJJIIJIGEHHFFDDDCCEADDDDCDDCACDCCDDDDDDD
@046
ATCAGTTTGAACAGTTGTCTGGATCCATTTTGTGGATGGCACCAGAAGTCATCAGAATGCAAGATAAAAATCCATACAGCTTTCAGTCAGATGTATATGC
+
CCCFFFFFHHHHHJIJJIJJJJJJJJJJJJJJFHIIJJJJJJJJJJJJHIJJJJJJJJJJJJJJJJJJJJJJIJJIHGHHHFFFFFFFDEEEEEEEFFEC
@047
GCAGTTTTTGGTAGCTCTTCTGGATGACCCTTCAAATTCTCATTTTATTGCCTGGACTGGTCGAGGCATGGAATTTAAACTGATTGAGCCTGAAGAGGAGG
+
1=;==2A?DDDC4CEB<C<3<CA:<FFEEEDCBEF>D>DCDDDAD*:9BDDA<?D@;8=BEI:8ADDCDDD>AAAABAAAAA(;A((-;>:99:>,9<(29
@048
TGGAGACTTCGGGATGGCCCGAGACATCTACAGGGCGAGCTACTATAGAAAGGGAGGCTGTGCCATGCTGCCAGTTAAGTGGATGCCCCCAGAGGCCTTC
+
C@@DF;BBHFDHHIJIIIIGJIIJGIGIIIIIGIJEHEHIIIFHHGGHGGFFFF=AC??BBDDCDACCCCAB@C>AA:>4>CA:CBCCDDDDDDBBDCCC
@049
GTTGAATGTGACAGCACCTACACCTCAGCAGTTACAAGCCTTCAAAAATGAAGTAGGAGTACTCAGGAAAACACGACATGTGAATATCCTACTCTTCATGG
+
CBCFFFFFHHHHGJJIJIIIJJJJJJIJIIJHIJEHJIGGGIIJJJJGGIJJJIJJIIEGGHGJJJJJJIIIJHHFFCDEACEECDDDEEDDDDDDDEEDD
@04A
GGAAAGCGAGAGGGAGACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGG
+
@C@DFFFFHHDFHIDGADHIIIIHIIGIGIIIIGEGG@EHDHEEEDEFCCCEECDDBDDDDDDBBBDDDDDCDDDDD@CAA@@CBBCCDDDDBDB@DABBD
@04B
CAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACA
+
@@@FDEDFHHFHHGEHIJHGIIEGGGDGII@GIIIIIIIG?HEGHGGIJGBGAGGHEECCFFF9ACE?@CCDAB@CDCDCCCCDDCA@CD?BDDCCCDD
@04C
CCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGC
+
CCCFFDFFHHGHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJHHHHHHHFFFFFFEDDDBDDDDDEEEDDEDEDDDD
@04D
GCTCACATTGCTGTTGCTGCTATTATTTTTCTTCGTCTTTTTAGGAGGAGGTTCCTTGGCTTTGCTTTTTTTATTCTCTTCCACTTCCTCTTTCCTTTTGT
+
@C@FDFFFHFHHHJJJGIHIGHIJJJJJJJIJJIGEHGIJJIJJIDHIEHGHHIIIIIIIIJJJJJJIJJHFAEEEDEEDDDDDDCDDDACCCACDDDDDA
@04E
CTAGCTACAGAGAAATCTCGATGGAGTGGGTCCCATCAGTTTGAACAGTTGTCTGGATCCATTTTGTGGATGGCACCAGAAGTCATCAGAATGCAAGATA
+
CCCFFFFFHHHHHJJJJIJJIJJJJJFHIJHIIJJJJJJJJJJJJIIJJJJIJIJJJJJJJJJJJJHIJGIIHHGHFFFFFECEEEEDDDDDDDDDDDDD
@04F
CAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCC
+
CC@FFFFFHHHHHJJJIJJIIJJEHHIJJJJIJIIJIJIJIJJJIIJIIGIGCHFH?CFFFDECEFEEEEDDBDDD:@CD@CDDB@@BCCDDDDDCDDCAB
@04G
CAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCAC
+
CCCFFFFFHHHHHJHIJJJJJJJJIJJIGIJJJJJJIJJJJIIIGIJFIIJJJJJJJHHHFFFFEEEEEEDDDDDDCDDDDDDDDDDDDDDDDDDDBDDDD
@04H
GAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGAC
+
CCCFFFFFHHHGHIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJIHHHHFFFFEECEEEDDDDDDDDDDDDDDDDDDDDDDDDDDDDDEDDDDD
@04I
TCCACAGAGACCTCAAGAGTAATAATATATTTCTTCATGAAGACCTCACAGTAAAAATAGGTGATTTTGGTCTAGCTACAGTGAAATCTCGATGGAGTGGG
+
CC@FFFFFHHHHHJJJJIJ:CFGJJIJJIJJJIIJIJJJIJJJJIGGIIJJHJJJJGIJIJBGHGIJIGHFGHEIHJIJHHGGHHFFFFFFEEEDDDABBD
@04J
ATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJGIJJJJJJJJJJJJJJJIHHHHFFFFFEEEEEEEDDDDDDDDDDDDDDDDDDEDDDDDDDDDDDDDDDD
@04K
CCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJHIJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJHGHBDDFDEEEEFEEDDDDDDDDDDDDDDDDCDDCDED
@04L
CATCACAATACTGGACCTCCCCCACGGGGGGAATCTACCCCAACCCCAACGTCCCCCGCCATCCTAACACCCACGTGCCTTCACACTTAGGCAGCTACTAC
+
CCCFFFFFHHGHHJIJJJJJJJJJJJJJJJDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDBDCDDCDDDDDDDBB?ADDDDDCCCDDDDDDDDDDDDCCDC
@04M
AGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAA
+
@@@DFFFFHHFHHIJIJJIJJJIJJGIIJIJJJJIJJJHIJJJJJIJJEIJJHHHHFDFFEEEEEDDDDDDCDCDCDDDDDDDDDBDDDDECDDDDDDD
@04N
CGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCA
+
@C@FFFFFHHHHHJJJJJJJJIJJJJJJJJJJJJJJJJJJIJJJJJJIIJJIJJJGHHHGFDDDDDDDDDDDDDD>CDEDDDDDDDDDDBDDDDDDDDD
@04O
GGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTT
+
CCCFFFFFHHHHHJJJJJJJJJJJIJJJJJJJJJJJJJIJIJJJJJJJJJJJIJJJJJJJJJJJJJJHHHHHFFEFFFEEDDDDDDDDDDDDEDDDDDDD
@04P
GAACTGTTGCACCGCTCCAGGTCACCTATCACGACAAATAACCGGCCTTCTCCTGACCCCGAGCAGCGGCCCCTCCGGTCCCCCCTGGACAACATGATCCG
+
@@CFFFFFHFGHHIGHIFHCAHGCHIGDHIIIIHIIFBDHGHHIGIGHIGJGGEHGFEFDCCBDD?BBBBBDDBBB<<5>@BDDBDDDDDDDBDCCC>CC?
@04Q
TGAAAAGCAAAGGAACACTTTTTCATTTGCTGAAAAAAACTTTGAAGTTAACTATCAAGAGTTACAAGAGGAGTATGCTTGCCTTCTCAAAGTAAAAGATG
+
@@@DFFFFHHHHHBHIJIIJJJIJHGJIJIJIDHIJIGIIJIGGHEHFGIJJEIIGHIIEHEGHGIFHHEF@D;BCEDEEDDDDCDDACDDDCCDDDDDDD
@04R
CCTCCGAGTCCCACCCGAAGCCATCCAGCCCCCGGCAGGAGAGCACACGCGTGATCCAGCTGATGCCCAGCCCCATCATGCACCCTCTGATCCTGAACCCC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJHHFFFFFFEDDD;BDDEDCDDDDDCDDDDDDDDDDDDDDDDDDDDDBDDDDEDDCDDDCDDD
@04S
GGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTC
+
CCCFFFFFHHHGHJJJJJJJJJHIJJIJJIJJJJJGIJJJJJJJIJJJJJJJJJIJJJJJJJJJJJGJHHGFFDDDDDDDDDDDDEDDCDDDCDDDDDCD
@04T
CCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCAC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJIJJIJJJIJJJJJJJJJJJJJJJJJJJIIJHHHHDFFFDCEEEEEDDDDECDDCDDDDDDDDDDDD
@04U
CTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGC
+
CCCFFFFFHHHHHIIJJJJJJJJJJJJJJJIJJJJJJJJJJJIIJJJJJJJJJJJJJJJJJJHHHHHGFFFFEDDCEDDDDCDEDEEDEDDDDDDDDDDD
@04V
TACACCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATGACATCTCCTGTGACTCTCACCTCTCAGACAACTAAGACAGATGACCCCCAATTGAAAAG
+
CCCFFFFFHHHGHJJJJJJJJJJJJJJJJJJJIIJFHIIJJJJJJJJJJJJJJJJIJIJJJJIJJJJJIJIJJJHHHHHFFFFFFEDDDDDDDDDDDDD
@04W
CTCGATGATAGTATTTCTGCTGCAAGTACTTCTGATGTTCAAGATCGCCTGTCAGCTCTTGAGTCACGAGTTCAGCAACAAGAAGAT
+
@@@;DD?DAHF??GFHGIEIC>FEH<<BF9?4CF4CBCE>BBB<FEFFHGIFEHIIE@G<BCGBFEGFGG;@DC@DHFAE=@@DBCC
@04X
GTTTCACCCAACAGATGCAAATACCATAATTACATGCGGTAAATCTCATATTTTCTTCTGGACCTGGAGCGGCAATTCACTAACAAGAAAACAGGGAATTT
+
@?@BDFFFGGBFHJGIIJJJJJJJJJJJJJJJIJIIJIJHIJJJJJJJJJDIJJIJIIIJIJIJ@GIJGIHFDDDDDDDDDDDCDDDDDDDCDDDDDDBDD
@04Y
CCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCT
+
CCCFFFFFHHHGHIIJJJJJJJIJJJJJJCGHIIIIJIJI?FGIJJJJJIJIJJJJIJJIJGIGIHEHHHHFFFFDDDBBDBDCBDDDDDCDDDDDDDCCC
@04Z
GTGAAATTTCAACCACAGCAGATGACTGCAGTTCAGAGGTAAATGGTTGCAGTTTTGTGATGAGAACAGGAAAGCCTACAAATTTATTAAGGGAAGAAGA
+
CBBFFFFFHHHHHJJIJJJJJJJJIJIJJJJJIJJJIIJDHHIJJJGGIIJHHIJJJHIJIJIJJIJJJJJJJHHHHHFFFFFEDCDDFEEDDDDDDDDD
@050
AGCAGCTCGAGAGTGTCGTAGAAAGAAGAAAGAATATGTGAAATGTTTAGAAAACAGAGTGGCAGTGCTTGAAAATCAAAACAAGACATTGATTGAGGAGC
+
@;;:DD;DAFAFF<?2A@<<C<EE>;:E;C;CD@ADFI*?DBDFE?BD4D3<FDFIAFI=@CE7@).=>7=;B?;:.>;BC2=BB;55:@@AA>5(,9@<(
@051
TGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTAT
+
??7ABDB;CCDAADA:<8CEECEE9CDD@>4BDBDCDCC(?DDA;2;6AC37=799=CDD=6;>A6;@;36-=>:A>>35><258=?>AA>>>>4>>:>>
@052
GGGTGAGCTGTGGCTCTCCCAAATGCTCCACATTGCCAGGCAGATCGCCTCGGGTATGGTGTACCTGGCCCCCCAGCACTTTGGGCACCGAGACCTGGCC
+
:+:227A+++222<<+?@=9;3A7><7A<1@A1@BB>*:)0?A)=*>5:7=6:/=AAAB746==;3=6>;(3=7==2,((5:=(&((+25-9;5833899
@053
GGAGGCTAAAGATAAGCAATTTAAAGAAAATTTTAAAAGGAATCTTGGATTATAATCATGAGATTTTAGGACAGCAAATTAATGACTTTACCCTTCCTGAT
+
CCCFFFFFGHHGHIJJJJIJJJJJJJIJJJGIIIJJJIIJGIHHIJJIGIIIJIIIIIIGIIJJJIIIIGIIIHIHHHGFFFFFFFFFFDEEEEDDDDDDD
@054
CAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACC
+
CCCFFFFFHHHHHJIIGIIJJJJJJJJJHIJJJJJJJJJJJJJIJIJJJJJJJJJJJJHHGHHFFFFDEEEEDDDDD;@DD?BDDDDD:CCDDDDDDEEDC
@055
CAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATAT
+
@@@DDDDFDFHHHJJGIAHHIJJJJEGIGDGHHGHIJJJJFIIJJJIIJGFGHIGHJIJJJJIIHHFHFFFBCDEEEECCCBB<?BCCCCDCCDCDEED
@056
ATTAGTAGGAGGGCGCTACTGGAATTTTCGTCTAAGTCAAATGTGCGATCTGCAGACAGCACCGATGGTGTCTCGCGGGCCTTGAGCATGTGGGACCAGTC
+
1::;1,2A+=:)<))<2))1:*11*10*?)0)08?/9<***)888)--.((.7)..((..)66'',,';((,(((('&&&)+:(+((++(++(0(++(++(
@057
TGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGG
+
?@<DDDFFGAB>A@CFHGEDABEEHIEHI<DGIIIGIIDIGGEH?FCHEEEDGE@CGCAHHFHHHFFDDF>AECCBCBBB<?CCCCCABBBBBCBCCCCCC
@058
CTTAACTCAAGTCATGGACATGGTGATTAAAGGTCCTTTGATTTTGTAAATCTTAAGTCGGGGGGCAGTTGGGGTAGATGGGGGCCTGTTTGAGAATTGTT
+
0(((()).)86:.2)2))))))3.))38))2<)8):)13)))).))09))))))0.)0)7('5')&&)(+((&&&&(((+38-&&&((3(48:(((+((++
@059
ACTCAGCAAGGTACAACTATTCTTCAGTATGCACAGACCTCTGATGGACAGCAGATACTTGTGCCCAGCAATCAGGTGGTCGTACAAACTGCATCAGG
+
CCCFFFFFHHHFHHHIJG>FHIGJIIJHIIIJHIJGHIJGIJJJGGGBHIIIJHEDGHIJGIIJJJJIJJJGGHGE?EEBDFBEDDCDBDCDDDDDDD
@05A
CTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGGGTT
+
@@@DDD8BFDFFAFIIFFB@GD:<CCAHHHEFFECFIIIIIFEGEFEIIEFBFFIFIFFICF@CEECDDDDDD<<3;B?BBBB??B?@BAB>ADBBB0959
@05B
CTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCAC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJIIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHHFFFDDDDDDDDDDEDEEEEFDDDDDDDDDDD
@05C
GGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAAT
+
CCCFFFFFHHHFFIJJIJIIIIIJGGIJEGIJCHHIIFJGGIGIGIJJIJBGCDGGGIIEIIIJJHHHFDFFFDEDDEDDDDDD?AC<?@@CCCCACCCD
@05D
GATGACACCTGTGTTGTCCCAGAAAAATTCGATGGAGACATCAAACAAGAGCCAGGAATGTATCGGGAAGGACCCACATACCAACGGCGAGGATCACTTC
+
C@@FDFFDHGFBFHIIGHIGIJIJIIIJJIJDIG@FHIJGIJJIGGIEEIJIJIJIIIBHJIEHGIHHFFFEEDDDDDDDCDDABDD@>>BDD>9ACDCC
@05E
CAGCACACCATGATTTGAATATTGATCAATCACAGTGAAATGAAATGTACATAAATAGTTCTCAGAGAGTAGAATCAACTGTGATTCCTGAATCTACAAT
+
===AA8@>+?@??4A7A?4A<CBA,?<B>A?C>@A=A*:==A==94?A>A97?BBAA700=4==4=A)7.=ABBA4;>B>7=>).=>AA;3).).>>;66
@05F
CTTGCTGGGAAGTGGAGCCTTTGGAGAAGTGTATGAAGGAACAGCAGTGGACATCTTAGGAGTTGGAAGTGGAGAAATCAAAGTAGCAGTGAAGACTTTG
+
@@@DBDD??CFHHFII;@?BHHGGIII;DCBFHFDC>DG>D@GGHGF?FB8BDF>FGGGG4CFHGCIII7=AHHCHEEEEDCC;;A>@@;ACACCACCCC
@05G
TGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTT
+
CCCFFFFFHHHHHJJJJJJIJJJJJJJJJIJJJJJJIIIJJGIJJIJJIJJJIJIJJJJIJIJJIJIHHHHHFFFEFFEEDDDDDBDDDDDDDEDDDDDDD
@05H
TAAAACATGAAGCAGAAGTTACAAATTACAAGATAAAACTTGAAATGTTAGAAAAAGAAAAGAATGCTGTGTTAGACAGAATGGCTGAATCACAAGAAGCT
+
C@CFFFDAFHFHHJJJJJCBGHCCBGHHGI@GFHIIJJIJG><@FCGGDDHFCDHIHIJJIECHCGGHH7CEHIDH@EEHFEFFFFDBECDDCACBDDCDD
@05I
GTGAAAATGAAAAGTTCTGTCTTTGATGAAGACAAAACTTTTGTAGCAGAAACATTGGAAATGGGTGAGGTTGTTGAAAAGGATACAACAGAACTCATGG
+
@@BFFFFFHHHHHJEHHGJJIJJJJJJJJJJJIJJJJJJJJJJGJJJJJJJJIJJJJJJJIJJJJCGHJJHIIJHHHHHGFFFFEEEECDBDDDDDDDDD
@05J
ATAGAATATGGTCCACTTGTGGAAGAGGAAGAGAAAGTGCCTGTGAGGCCCAAGGACCCTGAGGGGGTTCCTCCTCTCCTGGTCTCTCAACAGGCAAAACG
+
CCCFFFFFHHHHHJJJJJJIIJGGIHIJIJJJJJJJJHJJJJJIJJJJJJJJJJIIJJJJJIJJJHFBDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDD
@05K
CCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGT
+
CCCFFFFFFFHHFJJGBGIIFFHHIIJJJIJJGEHIJJJJIIJJIIGGIIJJGAEEEHF>DFFFEEEEEDDDD;@CDDDDD@?@DDDDDDDDDDDCDDBD@
@05L
GAACAACCACCAGGAGTCCTACCCTCTGTCAGTGTCTCCCATGGAGAATAATCACTGCCCAGCGTCCTCCGAGTCCCACCCGAAGCCATCCAGCCCCCGGC
+
@@@FFFFFHHHGHIJJEGIJJJJJEIIJGIJJFG*:CFGIJJJJJJJIIJJJGHGIJIJIJJJJJFHHHFFFD=ACDDDBDDBB@BBDDC8CC9?<B>BD@
@05M
CCCCCCCACACCATCCAGCACGCCAGTGTCCCCACTGCATCATGCATCTCCAAACTCAACTCATACACCGAAACCTGACCGGGCCTTCCCAGCTCACCTCC
+
@C@FFFFFHDFHGHHIIGHIJ?DGDAFE<FGIJIGGGGGGHIHEGDEFGHHGFFFDEEEECEE;ACCCD8?BDDDC??CCBDDCBBCCCD(48:@CCDCBD
@05N
GAAGATTTGAAAGCTGAGATTGTTTCTGCATCTGAATCCAGAAAGGAACTAGAATTAAAACATGAAGCAGAAGTTACAAATTACAAGATAAAACTTGAAAT
+
@@CFFFFFHHHFHJIJJJJJJJIJJIJJJJJJJIIJIJIGIJJJJJJJJIJIJJGIJJIIJJIGIJIIIIJJJIJJJJHHGFHGFFFFFEEEEDEDDDCDD
@05O
CCATCATGCACCCTCTGATCCTGAACCCCCGGCACTCCGTGGATTTCAAACAGTCCAGGCTCTCCGAGGACGGGCTGCATAGGGAAGGGAAGCCCATCAAC
+
CCCFFFFFHHHHHIJJJJJJIGGIIIJJIIJJIJIIJIIFIIGHGIJJJIGIFHHHHFDEFFEDECDDD6??BBDDDDDDDDDDDDDDDDDDDDDDCDCDD
@05P
CCAAGAAGGAGAATATATTAAAATGTTTATGCGCGGTCGGCCAATTACCATGTTCATTCCTTCCGATGTTGACAACTATGATGACATCAGAACGGAACTGC
+
:?@BD>?>FBDAD9@>BABAFCB<@4A<<4CAE?FE)8?FAEFAEDFE<C4@7))773?AA@DDB?(9(-;;3;>5:@>A:(5;(5((,:4:9<@<85(>:
@05Q
GAACAGATTGTGCAAAAGAACCAAGAAATAAAAAACATGAAATTAGAGCTGACTAATTCTAAGCAAAAAGAAAGACAGTCTTCTGAAGAAATAAAACAGTT
+
C@@FFFFFHGDBHHGIJJIIJIJJJJJJJJIJIIJIJJIJJJJIJJIJJIJJJIIIJJJJJJJIJJJJHHHFFFFFDECEEEDCDEDDDDC@CDDDDDC>A
@05R
CAGATGCAATGATCCTTGTGGATGGACAGCCACGCCAGGCCAAGGGTGAGCTGGGGCTCTCCCAAATGCTCCACATTGCCAGTCAGATCGCCTCGGGTATG
+
CCCFFFFFHHHHHJJJJJIJJJJJJJJJJJJJJJJJJJIJJJJIJJGJJJJJJJJJJHHHHHFFFFEEDCDEDDDDDDDDDDDDDDDDDDDDDDDDD<BCD
@05S
GTCAACATACTAGATGTTAAAGATGACTGTGGCCTCCAACTAAGGGTCAGCGAGGACACCTGCCCACTGAATGTTCATTCTTATGACCCCCAAGGAGAAGG
+
@;?DDBDDDHBFFGEG2AEDI>FHGE@HEIGGHG@FHIIIA??BFF0BDD>FG@:@FG@EGCEEHCEE@?CD>@>>CAC>>;>;>ACA<88;@??B?BBC?
@05T
AGAAAACCAAGTCATACCAGTGCTGTCTCAATTGCAGGAAAAGAAACTCTTTCATCTGCTGCTAAAAGTGGTACAGAAAAAAAGAAAGAAAAACCACAAGG
+
@?<DDDDAFHHDFBGGHIIIA?ECEDHGEHGIFGIIIIIIIIEGIIIIICBHH@HEFHHIA@FBFG@==FA)==DHFEFHFFB??AC>CBCCBB@BBBBB?
@05U
CTTTCCTGTTTTCTTATCCCAGTGCTTCGTTCCCTGGCCCGGCTGAAGCCCACTATGACCCTGGAGGAGGGACTGCCATTGGCTGTGCAGGAGTGGGAGC
+
CCCFFFFFHHHHHJJJJJGIJIFHIJIIIEHIJJJGIIJIIJJGIIJIIJIEIJIIJGHJHHGHBFFBCDDBBBBDDCCCDDCDD8?CCCDDD?BBDADD
@05V
CTCACCTCTCAGACAACTAAGACAGATGACCCCCAATTGAAAAGAGAAATAAGGTTAATGAAAAACAGAGAAGCTGCTCGAGAATGTCGCAGAAAGAAGA
+
CCCFFFFFHHHHFIJIJJIIGHIGIJIJJJIIJGJJJJJGIIJJJIIIEIIIJIHGIIIIJIJIJJIHHHGFFDC?BCEDDDDDCDCDBD@@BCCC?BCD
@05W
GTTCTTACTGGAGACTCAGGTGGAGTCATGCTTATATGGAGCAAAACTACTGTAGAGCCCACACCTGGGAAAGGACCTAAAGGGGTATATCAAATCAGCA
+
:1??=B:42=C:C;;A+2A:AADDB2A<A?DD>BEI4CD4:9?D9DD?DDDD99??DDDDCCDC@CDD?(=?CD@2?7;;AAA(';;55>A;>AA:,::5
@05X
CCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTC
+
@@@FFDFFFFHHHIJGGIGGIHCHIJJIJJGEIJGIJIJEIGGGHICEHDGGHH@DHIGEHHHHHFFFEFDE@CCEDDDDDDDBBACDDDDDDDDBDDDCC
@05Y
CCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCT
+
BCCDDFFFHHHHHIJGIIIIJJJJGJJHHGJJJIJJHIHIGJJJIGIGHIIHIIIIJIIIJJJJJJHHHHHFFFCCCEEEEEDDDDDDDDDDDDDDCDDD
@05Z
TCTCCTGTGACTCTCACCTCTCAGACAACTAAGACAGATGACCCCCAATTGAAAAGAGAAATAAGGTTAATGAAAAACAGAGAAGCTGCTCGAGAATGTCG
+
;?@D=DDD?DFFB>BBCEFG<EEF9FGEF>FEGEIDAFDF@DEC??@DBBFDFFGEFFFFEBECCE@EA:A>>AADDDDCBCCCB?BBBB@?@BBBBB@@B
@060
CGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCG
+
@@@DDFDDHFHHHGIHHHGIEFGCDHIGIGIIGFHFHGHGHIJJJHHFDFFFCEBCEEDDDD@CCCD?BCCDDCDDBDDBDB@BBBDDDD@CCDDDCDDD@
@061
GGTGCACATCATCCAGTCACGGGAGCCCTCCCTGAAGAATTCCAACCCCGACGAGATTGAAATCGACTTTGAGACCCTGAAGCCGTCCACACTGCGTGAGC
+
<+:DDDADHFFHFEHEBHGFHIBEEBA;?FGIIIIIIGHG>B8?FHII<G8@EEB9;;CCCCCCB?BBBCC>@5:?BCCCCACBBBBBBCCBCA@>)58?C
@062
TGGATACCAACCGGAAAACCCCTATCCCGCACAGCCCACTGTGGTCCCCACTGTCTACGAGGTGCATCCGGCTCAGTACTACCCGTCCCCCGTGCCCCAGT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJIJJJHHHHFFFFFFDDDD@BDDEDDDDDDDDDDEDEEDDDDDDDDDDDDDDDDDDDC
@063
TTGGAATACAGGCATGCACGAGAATGCTCAACTAATTTTTGTATTTTTAGTAGAGATTGGGTTTCGCCGCATTTTCGCGGCTTGTCTCAAACTCCCGACCT
+
-((=5.@)64143(..)))(((2@1)1)).6=>??88.7)(0))6)))0.6=)6>;3).((((()('-,'','((-'',,&&&&++5:((36::4+0&&05
@064
CTTCTATCCAATTTAAGAGTTTGGCCTCAATTTTCCTGCAAAGGGGTGGAAGACCGTGATTCATGGCGTTCCGTTTTATATAATTGGAGGAGCAAGAGCTC
+
-0(((.2.)6)<9=)2.=)3)32:46.:7@??=)833.)2))99(0(78>8=3).''((...).)69/==((,((-,((,6,7,(5;;(((((+(+(+(+(
@065
CAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATAT
+
@@@FFFFFFHHGHJIGG<IHGIJJIBEHIIJCHEGCGGIGIHIJJIEHHIIIIJJIJJJIIGGJGFHHFFE>BDCECEE@CDDCBBDDDDDDDCEDEDC
@066
GGTTTACAGAATGAAATGAGTCAAAAGATAGAAACCATGCAGTTTGAAAAGGACAATTTGATAACTAAGCAGAATCAATTAATTTTGGAAATTTCAAAGCT
+
@C@DFFFFHHFHHGIIIIIJCIGGIJIIIJJIJJJJJJJIHIJJJJJJIIJJJJIIJJJJIIIJJJGIJJIJJJJIHGHHHHHFFFFFDEECEDDEDDDDD
@067
TGCACAGACCACCCAGCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATG
+
CCCFFFFFHHGHHJJJJJJJJJIJIJGGIJJJJJJIJJJJJJJIJJJJJJJJJJJJJJJJJHHHHHHHFFFFFFEEEDDBDDDDDDDDDDDDDDDDDDDDD
@068
TGGTCGTACAAACTGCATCAGGAGATATGCAAACATATCAGATCCGAACTACACCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATGACATCTCCTGTG
+
@@@DDFFFHHHHHGIGIJIJCGHHJJJJJJJJIJJJJGGIEHIIGIHGGHGIJIJJJGGHJJJJJJHHGHHFEFFFFC?CEEEDCDDCDDCCDDDDDDCDD
@069
CCAGCCTGAGAGCACTCCCAGTTTGGATGCTGGACTTGCAGAGCTGGCTCCTCTGCAAGGACAAGGGTTAGAAAAGCAAGTCCTGGGATTGCAGAAAGGAC
+
CCCFFFFFHHHHHJJJJJJJJFHIIJIIIJJJIGIIJIJJJJIIJJIGGIIIGIIICGIJIJDHIJHEHHFFFFFEDEDECDDDDDDBDDDDCCCDDCBBB
@06A
CGAAGCCATCCAGCCCCCGGCAGGAGAGCACACGCGTGATCCAGCTGATGCCCAGCCCCATCATGCACCCTCTGATCCTGAACCCCCGGCACTCCGTGGAT
+
@@@FDDFFHGGHGGHIJJFIIEGIJGFHDHIJJHIIIFHGHFFFFFDECECEDCBDDDDDCDCDCDDCDDABCDDEDDDDDCDBDDDBDDDDDDDDD@DDD
@06B
GCTCGTTCATCGGGACTTGGCAGCCAGAAACATCCTGGTAGCTGAGGGGCGGAAGATGAAGATTTCGGATTTCGGCTTGTCCCGAGATGTTTATGAAGAGG
+
@7?BDDDDFDHFDIIIGGGGFAEHCGHGIIGGGHBHIGBFDHEH@GIIBEBB8=BBCCC@CCCCC:CB?@D@C?9<BBB?3@:55)&(++:@3:4(4>@AB
@06C
GAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGAT
+
B@CFFFFFHHFHHIJJIJHHIJJIJJJJJJJJJJJIIJJJJIIIJJJJIIIIJJJIFHFFDEEDDDDDDDDCDDEDDDDDDDDDDDBDDDBDDDDDDDDD
@06D
GGCCTGCTCCCAGTTCGGTGGATGGCTCCAGAAAGTTTGATGGATGGAATCTTCACTACTCAATCTGATGTATGGTCTTTTGGAATTCTGATTTGGG
+
@@@DDDD?=DFAHEFEHH:CG@<GCE>GGHIGEBFBG<F4*BFB<DFDDGGEGCAH==;@FFGIEHI:=AA:>AECD3?@CBAAC@>3(5(;>ACCB
@06E
CAGAGTCAAAAATTACAGATTCAATTTCAGCAATTACAGGCTAGTGAAACTCTGAGAAACAGCACTCATAGTAGCACAGCTGCAGACTTACTACAAGCCA
+
@@@DFFDDHFHFGGIEG@FHGIIIGIICHGGEGHIGEGFAGIGH?FFGHEADGHBDGEI9DFBGFEGGCH;CG;;7=CHHF>ED>DBDEEC@CECC;A?C
@06F
CCACATACCAACGGCGAGGATCACTTCAGCTCTGGCAGTTTTTGGTAGCTCTTCTGGATGACCCTTCAAATTCTCATTTTATTGCCTGGACTGGTCGAGGC
+
@;;DDADDFFHHHIDGA@D:DF?FGGDDHC8DEFHDCDFEHHIEG?AHHDEEEDCDDB;@@@CBCC;>CCCA>CAAA@BD5:A>>CCCB1<@ABAC>5<B5
@06G
CCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATT
+
?@@FFFBDHGGHHIGEBH+AICEEGEHFC>HGHEGGGH9CBHDHII9?DHHEHGE7CHDHGGIIIIEGIHEHEEDEFFDCEECEEDDDBDCCCBDDBCDDD
@06H
GATCCAGAAGCCCTTTTCTCCATGGCCTTTCCAGATAATCAGCGTCCACTGCTGAAGACAGACATGGAACGTCACATCAACGAGGAGGACACAGTGCCTCT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJHHHHFFFFEEEEDBDDDDDBDDDDDDDDDDDD
@06I
GAACATCATCCTCGTCGATTTGCTTGCCGGGGTGTTTGCAACAATTAGAAGGCGACGGGGTTGTATAGTTCTTTTTTCCTTCGCTAATTGGACGGCTTCAT
+
((03>))69)64)-8((-3)2))))2(.(<((7(--))).8):7=3):83.((',,,'3'05-&+(+(+4(3::((&(26(+(0&(&++((+(&&))0(++
@06J
CGGGAAGACCTGGCTTACATGAACCACATCATGGTCTCTGTCTCCCCGCCTGAAGAGCACGCCATGCCCATTGGGAGAATAGCAG
+
C@CFFFFFHHDHHJIJJJIIJJJIJJJJJJJJJJFHGIJIIJJJIJJJHIGGIJJGHIGHHHEFFFFECCEEDDDBDBBCDDCCD
@06K
GTTCTGTCTTTGATGAAGACAAAACTTTTGTAGCAGAAACATTGGAAATGGGTGAGGTTGTTGAAAAGGATACAACAGAACTCATGGAAAAACTTGAGGT
+
@@@FFFEFHHHHHGIIJIJJIIJJJJGJJJHIIJJJJJJJJJJJJJJJJJJGFEGHIGHIIJJIJJIHIIJIGHHGHFDFEFEEEEEEDDDDBDCD>CD?
@06L
ATGAAATTAGAGCTGACTAATTCTAAGCAAAAAGAAAGACAGTCTTCTGAAGAAATAAAACAGTTAATGGGGACAGTCGAAGAACTTCAGAAGAGAAATC
+
CCCFFFFFHHDHHGIHGHIJEJCHGGGGGHGGEHIIIJIJJEGIIGHIJIEHGIIJJIJIJJJCGGFHIIJJIBCHHEFFF?BEDCCCDDC@CDDCDCCC
@06M
GAAAAAAGAAAAGCACAAAAGGAAAGAGGAAGTGGAAGAGAATAAAAAAAGCAAAGCCAAGGAACCTCCTCCTAAAAAGACGAAGAAAAATAATAGCAGC
+
CCCFFFFFGHFHHJIIJJIIJJJJIJGIJHIJDHIFIIJJIIJJJJJJJJGHHHFFFFFEDDDDDDCDDDDDDDDDDDDDCDDBBDDDDBACDEECDDDD
@06N
CTGAGCCAAACATCCCCTTCCCACCACAAGGCTTTAAGCAGGAGTACCACGACCCAGTGTATGAACACAACACCATGGTTGGCAGTGCGGCCAGCCAAAGC
+
CC@FDADEFFHDHGIEHEHIGGGIAGEHIIIEHHGIIIGIIIIHIIIBHIHHGIIIH=C=CCHFFFBDDACABBACCC@C@;AC?<@@@BCCBBBBBCCCC
@06O
CACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGACTGCATCAGGAGATATGC
+
@C<BDDF>DFHHHIIBHIEHGICHGEEGIBDHEGIIIDGIECCHIIIGGBFIHGGEHFIE;EE@H;;CA>EDFDCCCBB?BACC>:AA@CCC>C8?>ACCC
@06P
GCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATAC
+
CCCFFFFFHHHHHIIJJIJJJJJJJJJJJIJJJJJJJJJJJIJJJJJJJEIJIJFEHGHHFFFFFDEEEEEDDDDDDDDDDDDDDDDDCCD@CEDDDDCED
@06Q
CATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATAT
+
?<@=ADDBHHHF?GB:ABEGEFG<8E3C@FFEGGGHBGHEFCGEADFHGCGFA=>CHEA>FIIGEHCCAA?DBC?C?>BB?CCC<AA>C@@AA>CC:>>A>
@06R
GGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGC
+
BCBFFFFFHGFHGJJJJJJJJJJJJJEHIJJJJJJJJIIJJJJJIJJJJJJJJJJJIIJJJJHHHHHFFFFDEEEED@CEDEEDEDDDDDDDDDDDDDD
@06S
CAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCT
+
===AAAA+?CBAAC??=+<<?<=A;73?A5=A>A?B?ABBA<=AAAAA2=<>A>9>;>;>ABAAA>@@9;>@>>5>3;>=;=53;===555(;;=;7<99
@06T
TGCTCTATGAACTCCTTCAGCATATTCTGAAGCAGAGGAAACCTCGGATTCTTTTTTCACCATTCTTCCACCCTGGAAACTCTATACACACACAGCCGG
+
1??1A??DFBFB<CAAF:CFBFCHEHF<EHHFFCDFF?F?9C?D@B@0?DDD@BFEAFF;F@E4@E@AC?7==B7;.>>;;A55@;@;A@=1=BB@@9<
@06U
CTGACAAGACCTTTCTCTCTTTCTTTCTGCCTCATGCTCTCTCCAACAGGCTTGCAGCCAATTTACTGGAGCAGGGATGACGTAGCCCAGTGGCTCAAGTG
+
CCCFFFFFHHHHHIJJJJJJIJJJJJJJJIIIJJJJJJJJJIJJJJJJHAHGIIJJJJJJJJJJCDHIIHGIHHHFFFFEEDBD@BDCDBACDD?CCDDDC
@06V
GTTCATTTATGTGTTATTGATGACTCCAATGAGCATATGCTTACTGTATGGGACTGGCAGAGGAAAGCAAAAGGAGCAGAAATAAAGACAACAAATGAAGT
+
CCCFFFFFHHHHHIIIJJJJJJJJJJJJJJJIJJJJJIJJJJJJJJGGIJIIIJJJJGJIGIJIIIJDHJJJJJHHHHFFFFEFEDEEEDDDDDDDDDDDD
@06W
GGCCAATTGACAGCAACACGTTTGAAATGAATGGCAAAGCTCTCCTGCTGCTGACCAAAGAGGACTTTCGCTATCGATCTCCTCATTCAGGTGATGTGCTC
+
@?@DD8DDDHDHAB?GBDHIFH@CCCGHIGHIG*;CB8B>*?D@GHIICGCIH?@=CFH>==C>DGGFHHHFDD@A?ABB@CACCCD;,>:,55>@BCCC>
@06X
CCACTGCATCATGCATCTCCAAACTCAACTCATACACCGAAACCTGACCGGGCCTTCCCAGCTCACCTCCCTCCATCGCAGTCCATACCAGATAGCAGCT
+
C@CFDDDE?FBDFGHGEHIEHHGGIJJJIJJIIGJJIIJJJJJIICHGGGIIGIHGHGE@CDDDEEEDEDDACDDACBDDD@?CDCCCDCCDDDCDCDDD
@06Y
AGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACC
+
@<@DDBDD?F:@FEGHGG<ECFDGHIFI<D@0BB*:D>DEHGIEG>6@B<BAACHEBBCCC>A@CCCCCCCBBBBBBB8<@B??ACCC<AACA@>>>?9?B
@06Z
CGACTTTGAGACCCTGAAGCCGTCCACACTGCGTGAGCTGGAGCGCTATGTCACCTCCTGTTTGCGGAAGAAAAGGAAACCTCAAGCTGAGAAAGTTGATG
+
CC@FFFFDHHHHHJIJGGJJJJGFHGGGJHIGIHGHIFJIJHGGIJJJJJJIJHHEFHEDCDDCCDBBDBBDDDDBDDDDDCCCDCCCCCDCCDDCCCCCD
@070
CAGGAACCCAGAGATTTTGCATATGACTCAGAAGTGCCTAGCTGCCACTCCATTTATATGAGGCAAGAAGGCTTCCTGGCTCATCCCAGCAGAACAGAAGG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJFHIJJJJJJJJJIJJJJJJJJJJJIJJJJJJJJJJJJJHHHHHFFFFFEEEEDDDDDDDDDDDDDDD
@071
AGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAA
+
CCCFFFFFHHHHHIJJJIIJJJJJIJJJJJJIJJJJJIHIIIIHIJIJJJJJHHHHFFFFEEEEEDDDDDDEDDDCDDDDDDDDDDDDDDDDDDDDDDD
@072
CCACGACCCAGTGTATGAACACAACACCATGGTTGGCAGTGCGGCCAGCCAAAGCTTTCCCCCTCCTCTGATGATTAAACAGGAACCCAGAGATTTTGCAT
+
CCCFFFFFGFDHHEGHGIIJJIJJIJGGGGHJHIGHIIJGHIJIIJJJIGHHHFDFFFCCEEDDDDDDDDDEDCDFEDDCCCBDDDDBBDD<CCCDCDDDD
@073
CCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJHIJJJJJJJIJJJJJHHHHFFFFFFEEEEEDDDDDDDEDDDDEDDEDDDDDDDCCDDDDDD
@074
CTTGAAGACCTTGTTGAAGAATTGAGCTTTTCAAGGGAACAGATTCAGAGAGCTAGACAGACAATAGCTGAACAAGAAAGTAAACTTAATGAAGCACATA
+
;??D7A;DD32<CE?CE>F<+<C<F:3<9C9F1CC@A??D;D;<@BDBB008?BDB8BC3.(=C)=@77)7@;C>ACC>;7;@@>A@A3@>AAAA>?=::
@075
ATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCA
+
??@FDDEFHHHDHDGGHIDGGIGHHGDF@BHGCAFGGGDD?GEHGFHGI>FDGHHIEHGI>EEGHFHGFBBAC=CA@A@5:C<<C?C?>@@CC@C>>CCC
@076
CTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTT
+
CCCDFEDDHGHHHJJICBGHIIIJGIGICHIJJGIIEIIHJIIHGIIGIFGIJCHE>EGHGGIJHEFEDEEEDDDCDDDDCDDDDD>?ADDDDDCABCB:>
@077
GGGGACTGGCAGAGGAAAGCAAAAGGAGCAGAAATAAAGACAACAAATGAAGTTGTTTTGGCTGTGGAGTTTCACCCAACAGATGCAAATACCATAATTAC
+
+:;?A0@?;8A;+2?@CAC37;==A7>?ABBABBBBBA=?>AB=AA>=AB>A=87>A.7=5.>A(.;;=>@@36;>@15(5;>:=;>:=9>=?????33:=
@078
CCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJGHIJJJJJJJJFHIJJJJJJJJJJJJJJJJJJJJJJJIHHHHFFFFFDDDDDDDDDDDDDDDEDDDDDDDDDD
@079
GTTCTTACTGGAGACTCAGGTGGAGTCATGCTTATATGGAGCAAAACTACTGTAGAGCCCACACCTGGGAAAGGACCTAAAGGTGTATATCAAATCAGCA
+
@=@DBDDD<?<D>?FCHIB?3CFFC<AFH>BFAGHIIIBGIFGG9?;BDG><FGEEECHIIIIGCDHEAAEC>;>??@C@C>>.;;>5@;AACC>>@CCC
@07A
GTGAACCTTATTGGGGAGCATTCTGATGCAGCAGAGCTTGGAAGGATGCTTCAGCTCATCTTAGGCTGTGCTGTGAACTGTGAACAGAAGCAAGGCATATT
+
CBCFFFFFHFFHFIIJJJIJFGIJIGIIJJJJJJGHIIJIEIIGHHIGIIIJJIIGHIIJIJJIJJJHHFGHFFDEFFEDECDDCDDDDDDDDDDDDDDDE
@07B
CCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCT
+
@CCDDFFFHHGFHIJJIJJJIJIIIIJJFGJJIIIIJGGIIJJJIIJDDFHIEGHHHIJJJJIIIIHEHGHFFFFFCCECCECDCADDDDBCCCBDDDDD
@07C
CCTAGCTGCCACTCCATTTATATGAGGCAAGAAGGCTTCCTGGCTCATCCCAGCAGAACAGAAGGCTGTATGTTTGAAAAGGGCCCCAGGCAGTTTTATG
+
CCCFFFFFHHHGHJJJJJJIJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJHHHHHHGFFFFFFDDDDDDDDDDDDCDEDDDD
@07D
GAGCCAGCGCCCATGAAGAGCAAGCCCCCTCCCACGTATGAGTCGGAGGAAGAGGACAAGTGCAAGCCTATGTCCTATGAGGAGAAGCGGCAGCTCAGCTT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJIJJJJJIJJJGIHHFFFFDEDEDDDDDDDDDDDDDDEEEDDDDDDDDDDDDDDDCDDDDDDDDDD
@07E
GCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGC
+
@@@FFFFFHGGHHIIIJGHICHIEIIJJIIHIJIIJJJIEGGIIGIJIJIJIIIIICHGIGDGIHEHHCEFFFFBDDCEDDDCDDDDDDDDDDDDDDDD?
@07F
TGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTAC
+
CCCFFFFFHHHHHJJJIJJJJJJJJJJJJJFHIJJJJJJHIHIJJJJHIJJJJIJJIJJJIHHFHFFFFDEEEEDDEEDDDDDDDDDDDDDDDCDCDDDD
@07G
CCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGG
+
CCCFFFFFHHHHHJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJIJHHHHHHFFFFEDEEEEDEDDDCDDDDDDDDDDDDDDDDD
@07H
GCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGC
+
@@@FDDFFHHGHHJJJJJJJJJJJGJIJJJJJJIJIJGIJJJJJIJJJJJJIJJJJDGIJHIGJEHHHHHFFFFFFDEEEEEDCDDDBDDDDDDDDDDDDD
@07I
CAGACTGTGTGAAATGCCTTGCTATACATCCTGACAAAATTAGGATTGCAACTGGACAGATAGCTGGCGTGGATAAAGATGGAAGGGTGAGTGGCATAGTG
+
@??==ADDBD;D?BGDBGHB<?EBAE?C9CFFFHFA?GIDDIFB9?DF4DBFIBFFFI<C<F>FG@=F8A:/5)?;;?;3;@>AC@B((99A@B?<AA:4:
@07J
CAAAAGTCCTCCCCTTGGAGGGGCACAAACGATCAGTAAGAATACAGAGCAACGGCCCCAGCCAGATCCGTATCAGATCCTGGGCCCGACCAGCAGTCGCC
+
CCCFFFFFHHHHHIJJJJJJJJJJJJJJJJJJIJJJGIIIJJJJJJIJJJJJJJHHFFDDDDDDDDDDDDBDDDEEDDDDDDDDDDDDDDDDDDDDDDDCD
@07K
CAGGTATTAATGGAAAGACTCAATCAATCTGATTCTATAGAAGACCCTAACAGTCCAGCAGGAAGAAGGCATTTGCAGCTCCAGACTCAATTAGAACAGCT
+
?@@==4B?FBAFF@GBFAFC@DBEHIII9<92AFDGCGBGGHII>@HHGIGGA@BBHHB8BHCBCF7@2@EG;C>A=?3?;C@);=A@;CC>>>CCCC9?A
@07L
GGTTCCTCCTCTCCTGGTCTCTCAACAGGCAAAACGGGAGGAGGAGCGCAGCCCAGCTGCCCCACCACCTCTGCCTACCACCTCCTCTGGCAAGGCTGCA
+
?@@DD?DDFHDFHACFHAIICDHCFF9AGA8CE?C:1?@FFEH:FHG@F8EBAA??B@;>AA??BD9??B@3(,:@CC?@CDDBB<?4+:@34282>???
@07M
CCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCT
+
@@@DDDDFHHHGFBEEEGGE@HGEEEHAFCGHCAFGDGGJJJIGEGA?BHGIJJIGBFHIIGGEGDHEHFGFFFE>>ACEEDDDDDDDDCDDCA?BCBDD
@07N
AACACTTTTTCATTTGCTGAAAAAAACTTTGAAGTTAACTATCAAGAGTTACAAGAGGAGTATGCTTGCCTTCTCAAAGTAAAAGATGATTTAGAAGAC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJIJIJJJJJJJJJJJIJJJJJJJJJJJFGIJJJJJHHHHHFFFFFFAEEEEEDDDDEEEDDDDDDD
@07O
CTGGTGCTGGGGTGCCAACCGGGAGTGGGGGCAATGTGGGACCTGCTACCATGGGCTCTGCGCGCTACCATGCATCCAGCCAGGACAGGGAGAATAAATCC
+
11+2?;++2++0@)+7?++):8A0?A>A9A<:<5737))'..5>>5;>(,;(-5;;(,:99:-5)5&&+38=833:38(38(89(238(+(&5;;33338(
@07P
CCGAAACCTGACCGGGCCTTCCCAGCTCACCTCCCTCCATCGCAGTCCTTACCAGATAGCAGCTACCCCATGGACCACAGATTTCGCCGCCAGCTTTCTG
+
@?@DFFDDFDDHHFIIIIEFBFCCFCAHG@FDGHGHIDGCHEGGG5@DEHHHGCH@CDBDFE;;>ACBD@CCCCA<?BBDCCDDD?@B9BDDDDCDDDDC
@07Q
AGATTTGAAAGCTGAGATTGTTTCTGCATCTGAATCCAGAAAGGAACTAGAATTAAAACATGAAGCAGAAGTTACAAATTACAAGATAAAACTTGAAATGT
+
;?;B=B?B>DFDD@E@G4<A<BCFHAGEHDCEDACFC@:?CG93?BGGEB<B??BF<F*?DD<)))=@GHC=4=@EIGEHAC?=.;?CDCA3(6;;>AA;>
@07R
ATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCC
+
?@?BDDDA+=2A:AC?G@FCF>GB;CC9AFEG?G???GCB@6@@F;F=FBCFACGDFE@A6.7.)=.=7)?DBB@@;>.55(,;(>:5(598?<2<<??BB
@07S
CAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAAC
+
?@@?BDDDBDHBH@E@CEBGHIG??GGIIAFHIICGEEGEDDEDGGGGIGIFHGECFG>;DHEGAA>7?7?;?;BC@;6@@@3=@B;<ACCCB9?C@@@>C
@07T
AGGACCCACATACCAACGGCGAGGATCACTTCAGCTCTGGCAGTTTTTGGTAGCTCTTCTGGATGACCCTTCAAATTCTCATTTTATTGCCTGGACTGGTC
+
CCCFFFFFHHHHHJIJJJHIIJIJJJJJJJJJJIJJJJJJIJJGHJHHHF?DFEEEEEDEDDDDDDDDDDDDDDDDDDCDDDDEEDDDDDDDDDDDDDDCD
@07U
CTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGC
+
@@@?BDDEDHFFBCBEH@AFHH=D7C;CG3C9?B@)?BDAGHIIGCH@A>DCB=C8=@;CHEDHHCEECB;>;>BA>6>AEA;;>;;?A9>AA:<<?>>:
@07V
GCAAAAGATATGCTTACAAATTTGACTTCCACGGCATTGCCCAGGCTCTGCAGCCACATCCGACCGAGTCGTCCATGTACAAGTACCCTTCTGACATCTCC
+
CC@FFFFFHHGHHJJIJJJJJJJJJJJIIJIIGGGIJJIJJJJIJJGGIJIIIJJGIJIJJGIHHEDD?CDDDDDEDACDDDDCCDDDDDDDDECCCDACD
@07W
CAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACC
+
CCCFFFFFHHHHHJJJIJJJJJJJJIJIBHIJJJJJJJJIJJJJIIJJJJJJJJIJGJHHHHHFFFFEDEEEDDDDD8?CCDDCDDDDACDDDDDDDEEDD
@07X
CTTTAGCAGTGCCCTGGGAAGGCTCTTCAGGAGCCATGTGGGGAGATGACAGAGGTACCCCCATGGCTCAGAGGTATGATCAGAATCCTTCCCCTAGAGC
+
@@?DDDDAD=?DFFA:A=GF;;CEFEBHEF<?EDG;DFIDFFIEFIIFFC@FFCF@AAEFCE6@BDC@AAA3;(5;AAA>3(5:>AAA@AABBBBB?:@<
@07Y
GACAAGTGCAAGCCTATGTCCTATGAGGAGAAGCGGCAGCTCAGCTTGGACATCAACAAGCTCCCCGGCGAGAAGCTGGGCCGCGTGGTGCACATCATCC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJIJJJJJJJJIJIJJJJJJJJIIJJJJJJJJHHHGFFFDDDDDDDDDDDDDDDDDBD<BD8?CDDDDDDDDD
@07Z
TGAAATTAGAGCTGACTAATTCTAAGCAAAAAGAAAGACAGTCTTCTGAAGAAATAAAACAGTTAATGGGGACAGGCGAAGAACTTCAGAAGAGAAATCAT
+
1114=AD;<,2C4EEBEEFA4F:3C>:+ACE???EE<DBC@DEII9DEE??<DD*8/?DE;BBC7AC;AAD=@?A((,3338;;>A535>>A:(9>>>4::
@080
CAAAGCCACAACTGGCTATTGTTACCCAGTGGTGTGAGGGCTCCAGCTTGTATCACCATCTCCATATCATTGAGACCAAATTTGAGATGATCAAACTTAT
+
@@@DADFDFFHHAGAHGIGFDBHHHCECHGFGGE@DCHGDGEIIIEGHHIII>F<FGGGE@GIGG@A@HCCHHGHFFFFDEDECC@BACDDCEDDCDDDC
@081
GTTAAGAAAGGCCAACGCAGCGCGAAGTCAACTTGAAACCTACAAGAGACAGGTAGTAGAACTACAAAACAGATTATCCGAAGAATCAAAGAAAGCAGAT
+
<??DDDDDD?FBFHGDEGI6FGEC0@G?DADHFE)8CAAHFGGHC@HCEHE9=DCB6>3(>@CCCCC@?=B<:@CCCC>?<?9<CC>C@@CCAACCCC3@
@082
CTGTCACAGAGACTGTCTGATCTTTCTGAACAATTGAAACAGAAACATGGTGAGATTAGTTTTCTAAATGAAGAAGTTAAATCTTTAAAGCAAGAGAA
+
@@@DFFDDHFHHHJIIGHIIJJIIJJJIHIGHGIIIIIGGIJJGGGIIIJFGEIGHJGIHHGIGGGHEIGGGHHEGHIHIEHHHHHFFFFEFFCEEED
@083
GCGCAGTGCGGCGCCTAGAGGGAAAGCGAGAGGGAGACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGC
+
@<@DDDDDFHHHHDCFGGCEGI:DCHGG@;@;DB:A=BBD=8>;;<5@9:,55505<5<@88<B<?8?<ACCCCCBB>B5<><>9<BA@A@@A>ACCCCAA
@084
CACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACC
+
?@@BB>AADCFFBFE?EGB?3ABCGHDGF?FE>GD?D81??FHA9/99<?BD4=FFBEHIII>;E@>A?9A;><A>?B:=AB?<>@A@;>AB?@B35(88A
@085
CAGAACCCTCCTTGAATCGGGCTGGTTTCCAAACAGAGGATTTTAGTCTATATGCTTGTGCTTCTCCAAAAACACCCATCCAGGCAGGGGGATATGGTGCG
+
CCCFFFFFHHHHHJJJJJJJJJJJJGHIJIJJJJJJJJJJJJIJIIFHIJJGIJIJIIJJJJJIJHHHHHFFFFDDDDDDDDDDDDDDDDD@DCDDD>CCB
@086
GCTCAAAGCCGTGCACGAGCAGCTTGCAGCCCTCTCTCAGCCCCAGCAGAACAAACCAAAGAAAAAGGAGAAAGACAAGAAGGAAAAGAAAAAAGAAAAGC
+
?@7DD?DD>FAD?FDH1@CBFAFGD>;9CFHEEHHGAD?FG>;FFBDEH3@3CCEH?E?BDBB@C@>?B?=?CCC??CB5<A@BCAC9<8?C?992<C9?<
@087
GTGTGAAATGCCTTGCTATACATCCTGACAAAATTAGGATTGCAACTGGACAGATAGCTGGCGTGGATAAAGATGGAAGGCCTCTACAACCCCACGTC
+
B?BDDFFFHHHHHJJJIJIJJJJIIJJIIJJGIIJJIJGHJJIIJJJIIJJJJHIJJJIJJJJFHIJJHHHHHHFFFFFDDDEDDDDDDDDDDDDDDD
@088
GGGCGCCGCTTGCCTTGGAAAGGTTTCTTCTTCAGGAAAACGGGCAAGAGAAGTGCATGGTGGGCAGGAGCAAGCCCTAGATAGCCCCAGAGGGATGCAC
+
CCCFFFFFHDHHHJIJIJJJJIJGHIJJIJJJJJJIGJJIDHIIEIIGIEGHH=AADEFFFFDDDDBDBBDDDDDDDDCCDDECCCDDBBBBBDBCBDDD
@089
CAGCGTCCACTGCTGAAGACAGACATGGAACGTCACATCAACGAGGAGGACACAGTGCCTCTTTCTCACTTTGATGAGAGCATGGCCTACATGCCGGAAGG
+
@C@DDFFDHFFHHIGIGIDHGIJIIJJIGEGIHDBEHIJGIGIIGHIGHGCGIEHIIJHGHHHFFFFFD?CECCACCCDDDDDDDDDDDDDCCCCDBDDBD
@08A
CTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCAC
+
@CCFFFFFHHHGFIIJJGJJIJJIIIIJJJJGIIIGIIGGIIIJEHGFCHJJEIIGHGIGIGGHEHHHHHFFFDCDDDBBCDDDDEE@CDCBDDDDDBDDD
@08B
CACCCAAGAACTGCCCTGGGCCTGTATACCGGATAATGACTCAGTGCTGGCAACATCAGCCTGAAGACAGGCCCAACTTTGCCATCATTTTGGAGAGGATT
+
?;??DAADFFDHFBGG<BA<CGFGE>F?BGE@G??BFGGHGCBBHG@DGCHGHCEGH<)@D)6AECEHDEEE?=AABCCCC:@CCCC@;>>@BCC>??<3:
@08C
CGCGTGATCCAGCTGATGCCCAGCCCCATCATGCACCCTCTGATCCTGAACCCCCGGCACTCCGTGGATTTCAAACAGTCCAGGCTCTCCGAGGACGGGCT
+
CCCFFFFFHHHHHIJJJIIGJJJJIJJIJIJJJJIJJJJJIJJJIJJIJIJJJJJJHFFDEEED?BD@DDDDEDDCDDDDDDDDDDDCDDDBBDDDDDDDD
@08D
CGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCA
+
B@@FFDDFFFFHHJJJJJJJJJJJJJJJJJJIIJJIJJJJIJJJJJJJJJJJJJJHHHHHFDDDBDDDDDDDDDDCDDEDDDDDDDDDDDDDDDDDDDD
@08E
ATCAGTTTGAACAGTTGTCTGGATCCATTTTGTGGATGGCACCAGAAGTCATCAGAATGCAAGATAAAAATCCATACAGCTTTCAGTCAGATGTATATGC
+
CCCFFFFFHHHHHJJJJGJJJJJJJJJJJJJJGHIIJJIIJJJJGHIIIIJJIJIJJGIJJIJIHIIJJJGJIJIJHHGHHFFFFFEFEDDEEEEEDFFD
@08F
TGGAAAACCGAGTTGCAGTCCTGGAAAATCAAAATAAAACTCTAATAGAAGAGTTAAAAACTTTGAAGGATCTTTATTCCAATAAAAGTGTTTGAT
+
@@@FFFFAHGFH?FEHJJJJIJIJJJJJJJJJJIJJJJJJJHIIGIIIGIGIJIHHIJIHIIIJIIGIGGHHHDFHFFC@EDDEDDEE@CDCCCDD
@08G
ATTCCTTCCGATGTTGACAACTATGATGACATCAGAACGGAACTGCCTCCTGAGAAGCTCAAACTGGAGTGGGCATATGGTTATCGAGGAAAGGACTGT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJIJJJJJJJJJJJIIJJJJJJJJJJJJJJJJJJJJJJJJHHEHFFFFEDEEEEEDDDDDDDDDDDDDDDDD
@08H
GGCTTCTCTGTGGAACTGGAAAGTGAAATTTCAACCACAGCAGATGACTGCAGTTCAGAGGTAAATGGTTGCAGTTTTGTGATGAGAACAGGAAAGCCTAC
+
CCCFFFFFHHHHHIJJJJJJIJJGHIJJJJJJJJJJJJIJJIJHIJJJJJIGJFHIIJIJJFHIJIJJ@FHIIIAEHHHCEFFDDFEEEEEDDDDDDDDDD
@08I
ACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCT
+
@@CFDFFFHHHHHJGIIJIJIJJJJJIJJEIJJIJIIHIIJJJJIGIIBDGHHEIIGGIJJJJJJJEHEFHEDDF@CEEEEDDDDCBDD@CDDDDDBDDDC
@08J
TGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTC
+
CCCFFFFFHHHHHIHIIIGIJJJJJIIJJJJJJJJJJJJIJJIIJIIIJIIGIIJJJJIJIHHCHHGFDFFFCCCCEEDDCCCCBCDCDDDDDDBDAABCD
@08K
CCTGACCGGGCCTTCCCAGCTCACCTCCCTCCATCGCAGTCCATACCAGATAGCAGCTACCCCATGGACCACAGATTTCGCCGCCAGCTTTCTGAACCCTG
+
?<?D=BD@:DDA=?E3+:1?**1?DEI;D39BDD<?D@@7BDC@CD;CEAA=)7C;;=77?;@56;;@;;;>;<3>A:A(;;05>??<AA:::4:::>;>3
@08L
AATAGTTCTCAGAGAGTAGAATCAACTGTGATTCCTGAATCTACAATAATGAGAACTCTACATAGTGGAGAAATAACCAGTCATGAGCAGGGCTTCTCTGT
+
CCCFFFFFHHHHHJJJIIJJJJJJJJJJHIIIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIIJIIJJJIJJJJJJIHHHHHHHFFFDCEDDDDDDC
@08M
GTGAAGATGGCGATGTGATTTGTTTGAATTCAGATGACATTATGCCAGTTGCTTTAATGGAAACGAAGAACCGAGAAGGGTTAAACTATATGGTACTTGCT
+
@@@FFDDAHBHHHGBAFGHGHIEFHGIIIIIIIIDIIIDGIIIIIIIIHHHIGHIGIGGDGHIIIHIIIIHFHEBCCC?>?ABDDA@AACDED@CACDC@C
@08N
CGAAACCTGACCGGGCCTTCCCAGCTCACCTCCCTCCATCGCAGTCCATACCAGATAGCAGCTACCCCATGGACCACAGATTTCGCCGCCAGCTTTCTGA
+
CCCFFFFFHHHHHJJJJJJJIJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJIHHHHHFFFFFEEEEEDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDE
@08O
TTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGC
+
@?@DFDFDHHCDFHIED@EIIEDHECHCHHEIGHBGGH>GHHFHHG>HEBED@FDFGGHEGIIGHH?E>;;BFDC;;>CCCDD;?CDADDDCCA@A<?B8<
@08P
AGGAAAAGAAAAAAGAAAAGCACAAAAGGAAAGAGGAAGTGGAAGAGAATAAAAAAAGCAAAGCCAAGGAACCTCCTCCTAAAAAGACGAAGAAAAATAAT
+
@@@FFBFDHHDH>FHIIIAEHHGGGIGIIIIIIGFGIGGIGGIGEIIIIIIIIIIEBBBCCECEBCCBBBCBB@CBCCC9ACCCCBBC9BBBB>ACBBCCA
@08Q
CCAAAGAAAAAGGAGAAAGACAAGAAGGAAAAGAAAAAAGAAAAGCACAAAAGGAAAGAGGAAGTGGAAGAGAATAAAAAAAAGCAAAGCCAAGGAACCTC
+
CCCFFFFFHGHHHIJJJJJIJGIJJEIDEHGIIJJJIIJJIIGIIIIGIJJJJJJHHHHFFFFF>CEEDEDBDDCDDDDDDDDBDDDDCDDCDBDBDDDDD
@08R
AAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGC
+
CCCFFFFFHHGGHJJIIJGHIJJJJJJIJJJJJJJJIJGIJJJIJJIJIJIIJJJJJJJIJGHHHGFFFEFFEEEEEDEDCDDDBDDDCCBDDDDDDDDDD
@08S
GCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJIJJJJJJJJHHHHHFFFFFDDDDDDDDDDDDDDDDDDDDDDD
@08T
CTTCCTCGACGCCACTTCATGTTCCAGTGCCTCGAGCGCTCAGGATGGAGGAAGACTCGATCCGCCTGCCTGCGCACCTGCGCTTGCAGCCAATTTACTGG
+
C@CFFFFFHHHHHJJJJJJJJHJJJJIIIJJJJJJJJJJGIIIJGHIIGJHHHHFFFFFDEEDDDDDDDDCDDDBDDDDDDBBBB?BDDDDDDDDDDEDDD
@08U
CCTGAAGGAGGTGCCGCGGAAAAACATCACCCTCATTCGGGGTCTGGGCCATGGCGCCTTTGGGGAGGTGTATGAAGGCCAGGTGTCCGGAATGCCCAACG
+
?<?DABD>D?D:CC@E8@CADDDD>@BB@<=CD;C=;@4=AA5=;3;@@@=;@A>?????AAA<;>>>(+++(:>:>A(828>(+44>>9>?<>>4<A>>>
@08V
GCGAGAGGGAGACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTAC
+
CCCFFFFBHFHHHJJIJJIJJJIJJJJJJIIJFHIIJJIIJJHHFHFEFFFD>@DDDDDDDDDDDDEEDDDDDDCCDDDDDDDDDDCB@BD@DDBDDDDD
@08W
GAGTTCAGCAACAAGAAGATGAAATCACTGTGCTAAAGGCGGCTTTGGCTGATGTTTTGAGGCGTCTTGCAATCTCTGAAGATCATGTGGCCTCAGTGAA
+
@@@FFFFFFHGFHJIJJIGIIJJHEHGGIGIJIJJIIGIIGIIIHIGHIEADGE;AHHCHFBDD@B@BC@CCDDCDEDDDAC:CCCCACCBDDBDCCAAC
@08X
TTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGC
+
CCCFFFFFHHHHHJJIJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHFHHHFFFFFFECEEEDDDDCDDDDDDDDDDDDDCDDD
@08Y
CGGCGGGGAAGATGTTCAGCGTAGAGTCGCTGGAGCGGGCGGGGCTGTGCGAGAGCCTCCTCACTTGGATCCAGACATTTAATGTGGATGCACCATGCC
+
???DDDDD:<684@@B9@C@A-;6=77@@>63?5;3;??09:-0)&029(505000<39<3<38:>:>(4><>4:0<(>B:>4(+4>+(:2(3>2+43>
@08Z
CTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACC
+
CCCFFFFDFHFHDHEGJGGGIJIJIIHIJJJJJJGGIJIJIIJIDHIJJHIJJJIHFHHFDDDFEEBEECDCCCDDDDDDDDD?BACCADCDCCCDDDEDD
@090
CAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGC
+
CCCFFFFFHHHHHJJJIJJJJIJGIJJJJJJIJIJJJJJIJJJJJJIJJIJJJJJJJJJJJJIIIIJJHHHGHFFFFFEEEEEDDDDDDDDDDDDDDDDDC
@091
AAAACAGGGAATTTTTGGGAAATATGAAAAGCCAAAATTTGTGCAGTGTTTAGCATTCTTGGGGAATGGAGATGTTCTTACTGGAGACTCAGGTGGAGTC
+
@@@DFFFFHAHHHIJJJIIGIIJJIGEGHIIEGGIGGHIIJIIIIJGGIGIIJJIJJIJICGDEHACAECH@CDDECEEEEEEEC??BDDDDC:>@BDD>
@092
GGCAGAGTGCCTCAAAAAGAAAAGAGATGAGAGACCACTCTTTCCCCAAATTCTCGCCTCTATTGAGCTGCTGGCCCGCTCATTGCCAAAAATTCACCGC
+
;?@DBBBDFFFHHGHGEHGHIIEDCGGGIGGAEEHJGHBGBBFHFGGHHFHI@CCFEIIE=@ADCEEECHB?@CAECBD8=8ACACAC@AA<AA>CCCBD
@093
GCCAGCTATGAACTATGATAAACTTAGCCGTTCACTCCGCTATTACTATGAGAAAGGAATTATGCAAAAGGTGGCTGGAGAGAGATATGTCTACAAGTTTG
+
CCCFFFFFHHHHHJJJJJJJJJJIJJJJJJJJJJJJIJIJJIJJJJJIJIJJJJJJIJJJJJJJJJJJJJH?EFFFFFEEEDDDDDDEDFDEEDDDD>CDD
@094
CTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTC
+
@@@FDDFEHHHHHJGFHIIGHIEHIJJJEHIJJIJIIIGGHGIIIGGEHCEHFECEEHBCCEFDFEEC?C@B@CCDDDDBBDDBDDDBDDDCCDDCDDDDA
@095
CGAGATCTAACAGGACTGTAAGTGCCACGAGAAAAAGTTCCACCCTGCTAGTCAGGGCGGTTGTATTTTTGGGAGTGGATCTTAGCTTTGGGTGGCCACT
+
0-(-2=).)8)))((.9=)))4)42)))((1<43:3<????=)3(()(0)//)8)..(-',3;,((,(,(37,(+828(32:(((+8(8((&2&&+22(4
@096
CTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTT
+
@@@FFFFFDHHHHIIBEEAIDHECGB;FGHEEHIDB:FGCGHHGHIIHHIADBHBFEHGGECHGIHGHHHGD;?@AEEEEDE;CA>CC=@BBD@?B>>CAC
@097
GTGCAAGCCTATGTCCTATGAGGAGAAGCGGCAGCTCAGCTTGGACATCAACAAGCTCCCCGGCGAGAAGCTGGGCCGCGTGGTGCACATCATCCAGTCAC
+
;@;BDADDADDF>FDA?FHIBHHGGIGA@<<<DFBGCFGGHGGGIB>>FGCDCHD=:@AEB?A<;8=7>?>CC9?8?59B059+2>A@CC@>>CCCC3:@A
@098
CATGGGCGCTGGCTCCTTCTTGCTCACATTGCTGTTGCTGCTATTATTTTTCTTCGTCTTTTTAGGAGGAGGTTCCTTGGCTTTGCTT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJIJJJJJJIJJJJJJJJJJIJJJJJGIJJJJJJJIJJIHHEHH?DFDDDEEDDDDDDDDDDD
@099
AGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACT
+
@C@FFFFFHHHHGJJJJIJJJJJJJJIJJIGJGIJJIIIGIIIJJJJJGIHHIIIJJGCEEHEHGHHHDEFDFFECCEDDDDDDDDBCBDBDDDDDDDDDB
@09A
TTTCAAACAGTCCAGGCTCTCCGAGGACGGGCTGCATAGGGAAGGGAAGCCCATCAACCTCTCTCATCGGGAAGACCTGGCTTACATGAACCACATCATGG
+
@CC?DFEFBFHD?EDFHAHIIIGGIIIEI<GBADGHAHIDIBG@@6DAEHEDDBFFDEEDDDCCA:;ACDD@?BBCDD?BACD@AA>@CDCBBDDACCDDC
@09B
ATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCA
+
@@CFDFFFFHHFBHIGHDHGGIHIIJEIIJIIJJJIIJJIGHIGJDEGIGGGIJIJIEIJGIJJIHHGFEBCCDDDDDDCCD@BDBDBCCCDCDCDDCCC
@09C
CAACCACCAGGAGTCCTACCCTCTGTCAGTGTCTCCCATGGAGAATAATCACTGCCCAGCGTCCTCCGAGTCCCACCCAAAGCCATCCAGCCCCCGGCAGG
+
1+12<?=7737C<=ABC?<3<ABB@B?BB*:*1:A7*1*?;?>=5?*?A4?/9==7;8=(4(-'-7;=',;;>;;('3(555;;((:9(5889;;==9.5&
@09D
CTTCAGAAGAGAAATCATAAAGACAGCCAGTTCGAAACTGATATAGTACAACGAATGGAACAAGAAACACAAAGAAAGTTAGAACAACTCCGGGCAGAGCT
+
CCCFFFFFHHHHHIJJJJJJJIJJJJJJIJEGIJJJJIIIJJJIGIJIHIJJJJJJIJIJJIJGIHIEFEHHFFFFFEECECEECDDBCDDDDDDDBDBDD
@09E
CAAGGCTTTAAGCAGGAGTACCACGACCCAGTGTATGAACACAACACCATGGTTGGCAGTGCGGCCAGCCAAAGCTTTCCCCCTCCTCTGATGATTAAAC
+
==;AA:DDCF?C<B?;A<F?A<:C?8E@?GD:?0BFHIC<?D?FI@GA===;.=F@E@=7A7/9>;3258599<CC@5>:>C>5>BC<:4(+4:>B@@@C
@09F
TGAGAACTTCCGTCAGTGGCAGCGTTACAAAGCCTTGGCCCGGAGGCACCTATCCCAGAGTGATGACACAGAAGCTCTTTCCTGTTTTCTTTTCCCAGTGC
+
??84A?3?D:ACDB=EA@FAE@1))8::D?:C;)*?DG9*07@'5@-56;?;7.)7;;;=>((.6;(;5=2((5(5(5@A((,,4>AC:@@(4:4((::>:
@09G
ATCATCAACCAAGAAGGAGAATATATTAAAATGTTTATGCGCGGTCGGCCAATTACCATGTTCATTCCTTCCGATGTTGACAACTATGATGACATCAGAAC
+
CCCFFFFFHHHHHGJJJJJIJJJJJJJJJJJJJIJJJJJIJJJJGIJJIJJHHHHHHFFFFFFFEEEEEDEDDDDDDDDDDDDDDDDDDEDEDDDDDDDDD
@09H
AGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJGIJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJHHHFFFDDDDDDDCEDDDDDDDDDDDDDDDDD
@09I
CAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTTATGGGCAGG
+
CCCFFFFFHHHHHIJIJJJIJJJIJJJJJJIJJJJJJJJJJJJJIJJIJIJJEIHIJJJJJJJHHFFDDDDDDDDDDDCDDDDEDDD9<>BDDDDDDDDDD
@09J
GGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTC
+
CCCFFBDDFHHGHJIIJJJIIJJIJIIJJIJGIGIJIGIIIGEIIGJJJGIGGIIIIGGGGIIJFGHHGHFFFFC>CEEDDBDDDDDDDDDDDDDCDCCC
@09K
TAGAAACCATGCAGTTTGAAAAGGACAATTTGATAACTAAGCAGAATAAATTAATTTTGGAAATTTCAAAGCTAAAAGATTTACAGCAGTCTCTTGTAAAT
+
:1:DDDD33AD;DAACCGEAHHEGIFD@DAFFE<F@EB>*:9?9BFE*?G??F9?DA4?:BF8.8=)@AFA)=C>DEE;CE@>3;?B@@>AAACAA5@>B@
@09L
GTGTGATCCAGAAGCCCTTTTCTCCATGGCCTTTCCAGATAATCAGCGTCCACTGCTGAAGACAGACATGGAACGTCACATCAACGAGGAGGACACAGTGC
+
B@@FFFFFHHHHHJJJJJJJJJJJJGJJJJJJJJJJJJIJJJJJJHGJIIJJJJJIJJJJJJJJJJJIJJHHHHHFFDCEEEEEDDCDDDDDDDDDDDDDD
@09M
CGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCA
+
CCBFFDFFHHHHHJJJJJJJJIJJJJIJJJJJJJJJJJJGIJJIJJJHIJJJHIJHHHHHFDDDDDDDDDDDDDD;ACEDDDDDDBDDDDDDDDDDDDD
@09N
CAAAGCTAAAAGATTTACAGCAGTCTCTTGTAAATTCAAAGTCAGAAGAAATGACTCTTCAAATCAATGAACTTCAAAAAGAAATTGAAATACTCAGACA
+
@@CDDDEDHGFDFGGGGCBHGICCGHGEHGCFDDGECGIIIDAHIHGIIIHGG<?FGHI:FABFBGGHGG>CHGGGIIIG<?EHFFFFFD@CCCACECCB
@09O
GCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGT
+
CCCFFFFDFFHGHIJGIGIJJIJJIHHIJJJJJIJJJIIJJJJIJJJJJIGHJIIJIJGIGHIIJJJGGHHFFDEDEEDCCDCCDDCCCDDDBDDDDCDDA
@09P
CAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCAC
+
CCCFFEFEHHHHHJJGI?FHIIIGJJHIJJGIIJEHJGIJJJJIIJJEGH@EHHHHHGFFFFFFFEDEDDACDDDDDD@BDDDDDDBDCDDDDDDBD>CCD
@09Q
AAAGACAACAAATGAAGTTGTTTTGGCTGTGGAGTTTCACCCAACAGATGCAAATACCATAATTACATGCGGTAAATCTCATATTTTCTTCTGGACCTGG
+
CCCFFFFFHHHHHJJJJJJJIJJJJJJJJHIJIJFHIJJJJJJJJJJIJJJJJJJJJJJJJJJJIJJJJJHH?DFCFEEEEEDEEFECDDDDDDDDDDDD
@09R
CGAATCTGCTAGTGAAGATTGGGGACTTCGGCATGTCCAGAGATGTCTACAGCACGGATTATTACAGGGTGGGAGGACACACCATGCTCCCCATTCGCTGG
+
C@CFFFEFHFD?<EFGHBIHGIJJJJIJJIJIGGGHIIIIGHEGFBFGBGGCBAEGIBBEHEHEECEEE;?AD;?=?5?<<BBB>@9@CDDDDDDDDBB@B
@09S
CCCCAAACTGGATCCGACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCAT
+
??@B;:ADCFFF<?G2CCEGE?GF;EADEF@FFBGFI@BDB>GEAFF?C=)BFB>;@EDDAE><<>@CA@;>A@BBBA@>@=?>?@8??<@BB<<(:A>@A
@09T
GCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJHJJHHHHHHFFFFFDDDEDDDDDDDDDDDDDDDDDDDDD
@09U
GGTTTGCCTTCCCGGATTGGGCCTACAAGCCAGAGTCGTCCCCTGGCTCAAGGCAGATCCAGCTGTGGCACTTTATCCTGGAGCTGCTGCGGAAGGAGG
+
CCCFFFFFHGHHHJJGJJJJJIIIJJJJJJJIIIJBGGHIJJJJIIFIJIJJIFGEEEEFFFFEDCCCCCDDDDDDCCD@C?ACDDDDCC@B>BDDA?>
@09V
ATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGT
+
CCCFFFFFHHHHFJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJIJJJJJJJJHGHHHFFFFDDDDDDDDCDDDDDDEDDDDDDDDDDDDDDCDDDDDD>
@09W
CACAAAAGGAAAGAGGAAGTGGAAGAGAATAAAAAAAGCAAAGCCAAGGAACCTCCTCCTAAAAAGACGAAGAAAAATAATAGCAGCAACAGCAATGTG
+
CC@FFFFFHDHHHGGIGGIFFGIIJGEHIGIGGIJJJJJJJJIGJJJGAGIIIIGGFHHFFFFFECAC@BDDDDDDDDDDADCDDCDDD@DDDDDDDCC
@09X
CTGATATAGTACAACGAATGGAACAAGAAACACAAAGAAAGTTAGAACAACTCCGGGCAGAGCTGGATGAGATGTATGGGCAGCAGATAGTGCAAATGAA
+
@@<;D?:=AC<F?@FFIEEGFFIEF9+9A9?CBD:DA3?3?DGDF4?D??BA<9;6458';EE<EBD<@;;3..>3;;;=;?=8<9(:@(,55:44::3>
@09Y
GAAATAAAGACAACAAATGAAGTTGTTTTGGCTGTGGAGTTTCACCCAACAGATGCAAATACCATAATTACATGCGGTAAATCTCATATTTTCTTCTGGAC
+
@@@DDD>D<DHFHBHIIII>ECEDEA@GHHGGHGDBGEBFGHCHEIICCCHICCBBFHI@HGFH@DEHGGEEE>EDEA<AADCCCCDACDDDCCCCA@AAB
@09Z
TGAAAATCAAGAAAGAACCCCACACTCCATGTTCAGAAATCGGCTCTGCCTGCAGTCAAGAACAGCCCTTTAAATTCAGCTATGGAGAAAAGTGCCTGTAC
+
C@CFFFFFHHHHHJJIJJJIIIJJJJJJJIJHIJJIJJJIJIIIJJJJJIIJJJJGIJJIJJJIFHHHFFFFFEEEEEEEDDCDDDDDDDDDCCDCDDDCD
@0A0
AGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACC
+
@??DDA+2CBC<@ECG=81@?FG<GIDDGAG?F9FF@D?;*?//?B@FFA/C=6=5;.7@ABAC:>@A>5>>@BBB?<B<8?23>?BA?BBAA>AAA9>BB
@0A1
TGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTAT
+
@@@DFFFFGHFHGJABFBGCHIGHHIHIGJJIIEH@FEGGBHGECHIGIGH@DDA@G@FFH@:EEBBCCEECEDDDDDC@C@@C???CCDDDDDCD@CDC
@0A2
GGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATC
+
CCCFFDFDHHHHHJIJJJJJIJJJJJJJJJJJIJJJJJDFHIIJJJJHIJJJJJJJJJ@EHHHHHFFFDEEEEBDDCDDDDDBBDDDCDDDDDDDDDDDDD
@0A3
GGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCAC
+
CCCFFFFFHHHHHJIJIJJJJIIJJJJJJJJJIIJJIJJIJIGIFHIJIJJIJJJJJJJJGHHHHFDDDDDDDDDDDDDDDDDDDDDDCCCDD5>CDDDDC
@0A4
CAGAAACATGGTGAGATTAGTTTTCTAAATGAAGAAGTTAAATCTTTAAAGCAAGAGAAAGAACAAGTTTCATTGAGATGTAGAGAGCTAGAAATCATTAT
+
:=?+42=DDFFA?@FGFFFHFEHFIICHEHHHBFFFFICFBGC@GFEGA@GIFEFDBFFII9B8=CFFFFIEGFDFE@CEEFAEEFB=BDCCCCCCBB>A>
@0A5
GAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGC
+
@BCFFFFFHHHHHJJJIJJJJJJJJJJJJJJJJJJJJIJJIJJJJIJJJIJJJJJHHFFFDDDDDDDDDDDEDDDDDDDDDDDDDDDDDDDDDDDDDDDDD
@0A6
ACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCAT
+
CCCFFFFFHHHHHJJJJGJJJJIJIJJIJGHIIJJGIJJJJJJJIJJJJJJIHHFHHHFFFFDCEEEEEEDDDDEDDDDDDDCDDDCDDDABDDDDDDDDD
@0A7
ACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCG
+
?<@DDDFDFBFHHIIGIGEIGIIII32C<CGIGH9CCDDDHE>GBFHFEHDBG@EGEAFCDGE@=CEEEEDEFFD@BEDDAACCCD?>@:5:?59??B>
@0A8
CCAGCTCACCTCCCTCCATCGCAGTCCATACCAGATAGCAGCTACCCCATGGACCACAGATTTCGCCGCCAGCTTTCTGAACCCTGTAACTCCTTTCCTCC
+
@@CFFFFFHHHHHIJIGIIJIGIIHIIJJGIJGGHIJJJJJIJJIGJIGIJIIIIJJJJIIGIIHHGFDDDDDCCCDDDDDDDBDCCDDDDDDDDDDDDDC
@0A9
TCCAGAAGCCCTTTTCTCCATGGCCTTTCCAGATAATCAGCGTCCACTGCTGAAGACAGACATGGAACGTCACATCAACGAGGAGGCCACAGTGCCTCTTT
+
0(7>8)6);<?<@?8<>8>>8<9=9<>@?86?>383=>93==;;?;>?<?87<8;??;???7=>79.;/6=9=?;;8;9==<83;<(85;666:<=<<28<
@0AA
GGCCCGACGTTGGGGCATTCAGAAAAACAGGCCAGCTATGAACTATGATAAACTTAGCCGTTCACTCCGCTATTACTATGAGAAAGGAATTATGCAAAAGG
+
@@@DDDADF<?FA@FEB;DD?D4:FGFIIEC=FF=@F@FCFFCFEFEEEEFFCEAEEEDBB>;ACCBBBB;?BBD>@>BABABBB>@?AA@AABBABBB98
@0AB
GACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACAC
+
@@@FDFF?DDHDHJGGIIGGHIIJIJJCEFEGIJIEHIIIIIIIJJIIIIIJIJGIGDGEIIJJJJIJFHHFFFFFFFDDACBCDBDDD@ADCDACCCD
@0AC
CCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATG
+
@@@DDFFFHHHGAEGHEHIIIGHDGEHIJ@CDHGIIJJIGIJGIIJIJHJIJDF?FGFGGHJJJIGIIIC;CEBFFFDECCCCCDCCCD@CCCB>BBDDDD
@0AD
TGAAATCTGATGCAGCTCTCCTTTGTTCTAGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATG
+
CCCFFFFFHHHFHIJJJJJJJJJJJJJIJFIDHIJIJIJJJIJJJJJJJJJJJJJJIGHIJIJJHHHHFFFFEDEDDEDDDDDDDDDCDDDDCDDDDDDD
@0AE
CAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCC
+
CCCFFFFFHHHHHIJIIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJHHHHHHFFFFEEDDCDDDDDDDDEDEDDDDDDDDDDDDDDDD
@0AF
CTTCTGATGTTCAAGATCGCCTGTCAGCTCTTGAGTCACGAGTTCAGCAACAAGAAGATGAAATCACTGTGCTAAAGGCGGCTTTGGCTGATGTTTTGAGG
+
1?@?DBBDDHD?FHAFH@FFEHEB>C9CF?EGGI911?C<F<DEGFH@HCDDH;FG>3=)=C;@87===.7)=AHHE3.5;2=@>>>(+22::(::<8(23
@0AG
CAGCGAGAAAGGAAGTCATCTTCATCCTCAGAAGACAGGAATCGAATGAAAACACTTGGTAGACGGGACTCGAGTGATGATTGGGAGATTCCTGATGGGC
+
CCCFFFFFGHHHHJJIJIJJJIJIJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJGHIJJJJHHFFFDDD;ACDDEEEDDDDD?CDDFDDDDDDDD
@0AH
GTTTTTGGTAGCTCTTCTGGATGACCCTTCAAATTCTCATTTTATTGCCTGGACTGGTCGAGGCATGGAATTTAAACTGATTGAGCCTGAAGAGGTGGCCC
+
@=@DFFFDHHHHHJJJJIJJEGGHIIIGIIJIJJIIGIJJJIIEFGGIJJJJ>FHIFHDHFBBHHHGHHFFCEEFEEEECEDCCCCDDDDDDDDDDBDBDD
@0AI
CCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGC
+
?@<BDABBDDF<BGGF;4CFGGIGG>GH@GEDCG<DEHFGIGCGEDFFGC8D@F=CC8=CEGHHCE>A;?EEEEEE;@@A=BB>'8:;CD@>A:@4:>CC
@0AJ
CTCATCCCAGCAGAACAGAAGGCTGTATGTTTGAAAAGGGCCCCAGGCAGTTTTATGATGACACCTGTGTTGTCCCAGAAAAATTCGATGGAGACATCAA
+
?<?DD;?AADD?DBED:2<3CFEEE<+A4CAAE<?DCCDDB=DDBD;DDC8B=A)@>CCCCEC;@CC==7@=.;?;>>?AA??>;A=;>A?>?A?=AAAA
@0AK
TTGAACTGTTGCACCGCTCCAGGTCACCTATCACGACAAATCACCGGCCTTCTCCTGACCCCGAGCAGCGGCCCCTCCGGTCCCCCCTGGACAACATGATC
+
1=?;DDBDD,:CD<EE<1<@93C2:9CE>D>D91?)?DA3B*9?)<48A@D;7=A)=A>;?=8??6/9?''&090()89?959???>97((++8289>>>A
@0AL
TCCCACCAAAAGCATAAAACGACCATCGCCAGCTGAAAAGTCACATAATTCTTGGGAAAATTCAGATGATAGCCGTAATAAATTGTCGAAAATACCTTCA
+
@@@FFFFFHGHBHIIIJIIIGHEGBHICGIIIJJIFIIGI?FHGIIIIIIEHIIJJJIJGHHHGHFDEFDFCECC@BBDCDDADCD@BDDDDDCDDDDCD
@0AM
TTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGC
+
CC@FFFFFHHGHHIJJJIIIIJJIIIGIIIIGHG@FHIIIJGJIJIJIIHHHHHHFFFFFFDDDEDCDDDDDDDDBDDD@?CDCDCDEDDDDCCBDDDDDD
@0AN
ATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATG
+
@@@FFDFDFHDDFIHIGGGIGE@FHHDGGGIGI:?BFEEFCGIIJIIIBHEHFIGEHIIIIJGBHGGHHHFFFCBDEDDDDDAADDD?C>:ACCCCCCCCD
@0AO
TATAATTGAGGTGGGCTGAAGGGGTTGGCTGCGTGATAGGAGGGGGGAGGACATGTGGTATGGATGGAGTAGAGGTGATGGCGGTGGGCGGTGAACTTGTG
+
((0(2).2)2))((-()23)8)2(<(<()0-((0(()0).))'-'')&&&+((+((((+((+(++8((2(((((++(((86(&&&)))(&)&)(+(+((((
@0AP
CATGATCCGCCGCCTCTCCCCGGCTGAGAGAGCTCAGGGACCCAGGCCGCACCAGGAGAACAACCACCAGGAGTCCTACCCTCTGTCAGTGTCTCCCATGG
+
CCCFFEFFHHGFHIHIIJJJJEHIGIIIGHJJJIIIGIGGHIJHFHHFEDDDDDDDDBBDCC?ADDDDDDBDD?CDDDCDDCBDDDDDD@CDD>CCDDDDD
@0AQ
CAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCAC
+
CCCFFFFFHHGHHJJJJJJJJJJJJJJJJJJHIIJJJIJIJJIIJIIJJIJJJJIJJJIGHHHHHHHHDEFFFFDECCCDDDDDDDDDDDDDDDDDDDDDD
@0AR
CCCACCAGAAGCTGTGAAGGAGTATGTTGACATCATGGAATGGCTGGTGGGGACTCACTTGGCCACTGGGGAGTCAGATGGAAAACAAGAGGAAGAAGGGC
+
??@D783B>FHHH>EBFBAD9C+AFFDE4<C<CGGGG@<FGF<;BF:99?F;@F(=7=CEHGECEH>CB?>5',5;;A355>CC<,,<9(+2<?BB?(80<
@0AS
GGAGATGTTCTTACTGGAGACTCAGGTGGAGTCATGCTTATATGGGGCAAAACTACTGTAGAGCCCACACCTGGGAAAGGTCCTAAAGGTGTGTATCTAAT
+
=?1AD:2,=ADD<E@,:E3+:C+++A+2+AC1?9*C*9?**?*0*))0)09)(//BC38/B)=)(-.((;C).652;(66(6@5>>AA:(,:((((((5(,
@0AT
CCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTA
+
CCCFFFFFHHHHHJJJJJIIIJJIJJJIJIJJJJIJJJJJJIJIJJJIIJJJJJIJJJIHHHHFDBBDDDDDDDDDDDDDDDDDDDDDDCDDDDDDDDAC
@0AU
AGCTACTTCTCTGCCACAAACTGTGGTGATGACATCTCCTGTGACTCTCACCTCTCAGACAACTAAGACAGATGACCCCCAATTGAAAAGAGAAATAAGGT
+
CCCFFFFFHHHHHJIJJJJJJJJIIJHIJJJJJJJJJJJJJJIJJJJJIIJJJJJJJJJJIJJIJJJJJJJJIJHHHHFFDDEEEEDDDDDDCDDDDDDDC
@0AV
ATTGTTTTTTTTTATTAAAAAATGATTTAGAAGACAGTAAAAATAAACAGGATTTTGTGTATAAAAGGGAACTTAAAGCACCTAAGGAATGGCCTCATTTG
+
(;<(84=?1>-(:(18)22=)-(99=)<3<?1=1))9/)./))6;=)<;?(.))...(.).(..(((((,((:026:502;(:2((((8((+(((++++(+
@0AW
CGTCACTTCCCTTGTGGGAATGTCAATTACGGCTACCAGCAACAGGGCTTGCCCTTAGAAGCCGCTACTGCCCCTGGAGCTGGTCATTACGAGGATACCAT
+
@@@BD?DD?CBFFGACDA=E?FCFFHEAHGC@AHF9B?BGEGGEEGEGDFACF@FHD@DEHHHHBBCAEE@C?BA?ABA3<:?,5:44:A?@>BB<:>ACC
@0AX
ACAAACTGTGGTGATGACATCTCCTGTGACTCTCACCTCTCAGACAACTAAGACAGATGACCCCCAATTGAAAAGAGAAATAAGGTTAATGAAAAACAG
+
CCCFFFFFHGHFHIJJJJJJJJJJJIHIJJIJJJJJIJJJJJIIJJJJIJJJJJJJFDHIJJJJJIJJJHHHHHHFFFFEEEEEE>CCDDDDDDDDDDC
@0AY
CTGAGGATGCCTCCTCCTTGCCTGAAGCCAGTCAAGAGGCAGGGAGCAGAGGCAATTCCTTTTCTCCTCTGTTGGAAACCATAGAACCTGTCAACATACT
+
@@<D=BDDBD?FHG;FHICHIEHHGEH@DGHIIGGHIIIIIIBBFFECHDGACDC@E;=DAEHFEHD>BDE;>>;>>A;==CACCCCB<<:@CD::9@CC
@0AZ
CCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGT
+
CCCFFFDF?FDFDGIIIGIGCFDHGIGHGIIIIDHIGAGIGIII@FGGII;=?.?EE>B7BDACC>CEECCB@5>ACC@??A<??CCCBC@?AC@CCBBA:
@0B0
CTGCAGATTATTGGACTTGGCACTTTTGAGCGTGGAGTAGGATGCCTGGATTTTTCAAAAGCAGATTCAGGTGTTCATTTATGTGTTATTGATGACTCCA
+
CCCFFFFFGHHHGIIIJJJJJJIJJJJGGIJIHGIGHGHHIIJJJJIIIDGGIJJIJJIIIJIJAGHEHHHAEFFFFFDFDEECDCEADDDDEDEDDDDD
@0B1
GGAGGATCAACCACAGGTTTGTCTGCTACCCCCCCTGCCTCATTACCTGGCTCACTAACTAACGTGAAAGCCTTACAGAAATCTCCAGGACCTCAGCG
+
CCCFFFFFHHHHHJJJJGHJJIJJJJJJJJJJJJJJJJJJJJJJJJJIJJHHHHHFFFFFFEEDCBDDDDDDDDDDDDDDDDDCDDDDDDDDDDDDDD
@0B2
CTTTTCTCCATGGCCTTTCCAGATAATCAGCGTCCACTGCTGAAGACAGACATGGAACGTCACATCAACGAGGAGGACACAGTGCCTCTTTCTCACTTTG
+
C@@FFFFFGHHHHJJJJJJJJJGJJJJGIGIGHIGFIJJIJJJJIJJJEIJIJJJGIJIIJEGEHHIJHHHFFDDDBDCDD?C@CCDDDDDDDDEDDDDD
@0B3
CCCGAGCCAGCCCTCCTCCCTGGCCATGCTGGACCTTCTGCACGTGGCTCGGGACATTGCCTGTGGCTGTCAGTATTTGGAGGAAAACCACTTCATCCACC
+
@@@BDADDF?DFBFH?HDHHHGIDGDHECFHIEHH;BB<DHGHID@C<AGAGBHDE>CCCCCC>>????2::C((,5>;CA?B7<CCABBBA@CAA(4:>?
@0B4
GAACAGTTGTCTGGATCCATTTTGTGGATGGCACCAGAAGTCATCAGAATGCAAGATAAAAATCCATACAGCTTTCAGTCAGATGTATATGCATTTGGAAT
+
CCCFFFFFGHHHHJIJJIJJJJJJGHJIJIGIIIJIIIJJGHIJJJIJJIJIJJJJJIJIJJIJJJIJJIIIJJJHGHHGHFFFFDEECEFEDDEEDDDDD
@0B5
AAAGAATGCTACGCGACAGTTTGAAGATTGAAAGGGAGGCAGAGGAGGAAGAAGAGTCCGAAGAAGAAGGTGAAGAGACAGCAGAAGACAAAAAAGAAGAC
+
10;8(()2))))(-((-(-):;)2))<)917)))(0.('((((.8353-6..))6=)6(('(,,(,(,,((((((,+(++88(+68+3((6/2(&&(++(+
@0B6
TCTAAATGAAGAAGTTAAATCTTTAAAGCAAGAGAAAGAACAAGTTTCATTGAGATGTAGAGAGCTAGAAATCATTATTAACCACAACAGGGCAGAAAATG
+
CCCFFFFFGHHHHJIJHJJJJJJJJJJJIJJJJJJJJJJJJJJJGGJJJJJJGIJIIFGHIJIJJJJJJJJJJJJJJJJIHHHHHFFFFEDDDDDDDDDDD
@0B7
TCAGACAAGAAGAAAAAGAAAAGGGTACACTTGAACAAGAAGTTCAAGAATTACAACTTAAAACAGAATTGTTAGAAAAACAGATGAAGGAAAAAGAGAAT
+
111A:::?:?D>F3A??@@EG99EFCF<C??F<<D*BG@;99*9*00B<FFF><.8)=FFC@FA;;7@47?.=))7?@BB6?@@3>A5;3=ABB?6(59A(
@0B8
TGAATGTGACAGCACCTACACCTCAGCAGTTACAAGCCTTCAAAAATGAAGTAGGAGTACTCAGGAAAACACGACATGTGAATATCCTACTCTTCATGGGC
+
@CBFFF?DHHHHGJJJIIJJIIIJGHIJGIIIJJJDGGIIJJJJJJIJJJJDEGIGGCEHEHIIJJJJHIJJHHFFDCA@@DDDEFDDDDCCDDDDDDDDD
@0B9
CACCTTCTCCCCAGCCCTCTTCACAACCTCTCCAAATACACAGACAAACTCCAGAAAGCAAGAATGCTACTCCCACCAAAAGCATAAAACGACCATCACC
+
CCCFFFFFHHFHHIIJJJJJJIJIIIIGGIJJJJJJJJJIJJIJJJIJJIJIIIJJJJJJJJIJIIGHGHHHFFFFCDDDDDDDCDDDDDDDDDDDDDDD
@0BA
GCCCGACGTTGGGGCATTCAGAAAAACAGGCCAGCTATGAACTATGATAAACTTAGCCGTTCACTCCGCTATTACTATGAGAAAGGAATTATGCAAAAGGT
+
CCCFFFFFHHHHGJJJJJJJIJJJJJJJJJJJIJJJJJJJIJJIJJJIJGIJJJJJHHGFFFFFEEEDDDDDDEDDEEDCDDDDDDDDDDDEDDEDDDDD+
@0BB
ACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCG
+
@@@FDFDDFDFBFHEEEGH@EGGIDHCFGIIGHIIIII@FFHBGBFHHAFHAFCFFHE>E=CG>EE>EHHFBDFFFC@ACB@CD<=B?C>AA?BC?B?B
@0BC
CAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCC
+
C@@FFFFFHGHHHJJJIJJHIJJIJIJIIIJGIJJGIJJEHJJGIJIJIIIJJJIIJJIHFGHGHFFFFDEDDCDDDDCDDCDDEDDACDDDDDDDDDDDD
@0BD
CTGCCCTGGGCCTGTATACCGGATAATGACTCAGTGCTGGCAACATCAGCCTGAAGACAGGCCCAACTTTGCCATCATTTTGGAGAGGATTGAATACTGC
+
@@@DDDDFDFDDHHEFHGHIGIIEGHGHED@FGABFDIECFHICGIGIEFH>FE@CGHIJJGGHCA=CDCDEA>C@CCDDDC>>C?@BA?CCC@CDDDCC
@0BE
AGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACC
+
CCCFFFFFGHGHHJJIJJJJJJJJJJJJJJJJJIJJJJJJIJJJJJJIJJIJHHHFFFFFEBCEEEEDDDDDDDDDDBDDDDBDDDDDDDDDDDEDDDDDD
@0BF
AATAAACAGGAATTAGAGTATAAAAGTAAACTTAAAGCACTTAATGAAGAGCTTCATTTGCAAAGAATAAATCCAACTACAGTGAAAATGAAAAGTTCTGT
+
@@CFFFFFFGHHHIJGHIFGHIJJIIFFDHJJJJJJIIIJJIJIIGHIHGIJJJIJIIJIJGIIJJGJJJIIJIJIIIIGDHHHHFFFDFFEEEE@CEDCC
@0BG
CCAGAAGCCCTTTTCTCCATGGCCTTTCCAGATAATCAGCGTCCACTGCTGAAGACAGACATGGAACGTCACATCAACGAGGAGGACACAGTGCCTCTTTC
+
;;;DBB;BFHFFBHG9EHECG<9CFGHEGDHIFGGAB@?AD6??10??<FFB<<8BFFEE>F:@GC@<=A?=BCB7;>'=>:8?6,9C<<?5>ACA>>@@4
@0BH
GTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTT
+
@@@FFDDEDFHDFHIEIIIIEGIJIGGHFHGBGGEGGGHGHHIGIIGIGGIJJJJJIGHGHIJIJJHHFFFA>DFFDDCBB=CCEEEACCCEDCDDDDAC
@0BI
CCAAAATTTGTGCAGTGTTTAGCATTCTTGGGGAATGGAGATGTTCTTACTGGAGACTCAGGTGGAGTCATGCTTATATGGAGCAAAACTACTGTAGAGCC
+
@@@DDDDFHBD?DHGCGDGHHIIIIGICFHIGIEGIIIIII>GBDHHHHIIHIICAECGIII@FHII=CEC@CEHGEEEDDDEFCEECACCCCC@C>@CCB
@0BJ
CGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCG
+
;?@DDDFFHHGHHIIJIC@EGHGHGGG@?2BGGHIDDHHHHBHEGCA8??BDEEBECCEDDCDDDD?58:A3?C>BB<9<BBDDB88?>C3:CDDCCDDDB
@0BK
CTTCTCGTCCTCAGAGTCGGAGAGCTCCAGTGAGTCCAGCTCCTCTGACAGCGAAGACTCCGAAACAGCATCTGCATTGCCGGGACCGGATATGAGCATG
+
@@@?BDDDDFHHHIGIFFGHGEEGCEDHHI?FE@9BFAHEEHAHCGBDHEGGIGIBEHE>@BBB@DDC@DDD@CCDDDCCDDDB@BDDBDBDCDDCCDCC
@0BL
CTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATG
+
=?@BDDDDFF?FFG@FHIIIGFFB?GHCBBBFG@D?DHFGGGHHIIAHIDHHEC@@CBEAC>A@CC>@>;>ABCB?BBB?<A:>:4:<ACBB?BB>C:@C>
@0BM
CTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCC
+
@@@FFFFFGGGHHJJJJJIJHHIJJJIIJJJJIJJJJJJJJJJJIIIIIJIIGJJGHHIIJHHEHHFFFFFEEEEEDDB??BDDDDDDDDDCDECCDDDDD
@0BN
CCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJIJJJJJIJJJJJJJJIJJJJJJJJJJJJJJIIIHGHFFFDFFEEEEFEDDDDDBDDDDDDDDDCDDDDEDD
@0BO
GATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCC
+
@@@DDDDD;?FFFB??<AAICA?:AEFEEFFD>:9?CGDD@D?:?@?=8B<B7@@G?HH>GE)=CA;7?;BBDC>@@CC5;;;=CA@>>999;?2+<8<38
@0BP
GCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGC
+
@@@FFDFFHGFHFHIGGJIIHHGHGGCGHGGGAEHGGIIJJJIJIJIHIIJIJIJGGGI@GGHIFEHHGHEFFFFCDBCCCCDBDDCCCDDCBDDDDDDD
@0BQ
CCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTTATGGG
+
CCCFFFDFHHGHDHHGIIIJIGHJJIIGIJIIJIIJFIIJIJJIIIIGGDIGJGHGGIDHHFHHHHHDFCCDDDDDDDDDDDCCDDDDDDD39<?CDDDDD
@0BR
AGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCT
+
@C@DFFFFHHHHGIJJJJJIIIJJJJIJIGIJJJIJJJIIJJIIJIJJJIJIJIJJJGHGHFFFFEEECEEDDDDDDCCDDDDDDDDDDBDDDD>CDDCD
@0BS
ATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCC
+
CCCFFFFFHHHHHJJJJJJJJJIJJJJIJJJJJGJJJJJJJJJJJJJJJJJJJJJJJJJJJCHHHHHHFF@CEFDEDECDCDDDDDDDDDDDDDDDDDDDD
@0BT
CTCCTCCATCAGTGACCTGAAGGAGGTGCCGCGGAAAAACATCACCCTCATTCGGGGTCTGGGCCATGGCGCCTTTGGGGAGGTGTATGAAGGCCAGGTGT
+
@<@DDDDDH?H<AA@?EGGBC<GHB@F3?ED@GHDBHIGBHEIIIGFHH>A;7@@A>'',5;CB?8A@>B-995>C@?<B(59<?:>:4:C4388?<8+4+
@0BU
CAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTAC
+
CCCFFFFFHHHHGJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJHHFBDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDACDDEDD
@0BV
CCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTTATGGG
+
C@@DFFFF?FFHF<FGFHGHFIHEGGIEIIDGCGHFHG>FHGHIIHIIGGIIIDGGGIHGGCECAEE<<>AA?ABADDDB@?5@@C>ACBB399@CCACDB
@0BW
AAGAATTACAACTTAAAACAGAATTGTTAGAAAAACAGATGAAGGAAAAAGAGAATGATCTTCAAGAAAAATTTGCACAACTTGAAGCAGAGAATAGCATT
+
CCCFFFFFHGHHHJIJJIJJJJJJIJIIJJJJIJGIJJIGIJIIJIJJIIJJJJIJIJJIJJIJJIJIJJJGHHHHHFFFFFFEEDDCCCCBDDCDDDCED
@0BX
CCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAG
+
CCCFFFFFHGHHHJJJJJJJIJJJJJJJJJJIIIIIJIIJJJJJJIJJJJGIJIJGHIJJJJIIJIJJHHGHFFFFFDDEDDDBDDDDDDDDDDDDDDD
@0BY
TGAAGTTGTTTTGGCTGTGGAGTTTCACCCAACAGATGCAAATACCATAATTACATGCGGTAAATCTCATATTTTCTTCTGGACCTGGAGCGGCAATTCAC
+
@@<DDDDADHHFHEGGHHEEFHFGEFIIIEGHGIJFD9BFFFHG@EGGHIGIEAGHJGIDHIIHFIBEHF:CEHFBDDDEECEA@ACDA?;=8;>BACA@:
@0BZ
CCGTGGATTTCAAACAGTCCAGGCTCTCCGAGGACGGGCTGCATAGGGAAGGGAAGCCCATCAACCTCTCTCATCGGGAAGACCTGGCTTACATGAACCAC
+
@@CFFFFFHHHHHJJJJJJJJJJIJJJJJJJJIIJJJJJJJJJJJJJIIHHHHFFFDEDDEDDDDDDDDDDDDEDDDCDDBDDDCDDDDDDDDEDDDDDDD
@0C0
ATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTGAGTTGCTAAGAGAGAAAACCAAATAAGAATGAATGTGTT
+
CC@FFFFFHHHHHGGIJGIGHHIIIIJGIIIIIJIJIJJJJJIGJJIJIJJIJEGIGIIG=C>CEEFFFFFFFEEDDCDDDDDBDDDDDDDDDCCDC@C>C
@0C1
AACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJFHJJJJJJJFHHJJJJJIJJJJJHHHHHFFFFEDDDDDDDDDDDDDEEDDDDDDDDDDDDDDD
@0C2
TGAAAATCAAGAAAGAACCCCACAGTCCATGTTCAGAAATCGGCTCTGCCTGCAGTCAAGAACAGCCCTTTAAATTCAGCTATGGAGAAAAGTGCCTGTAC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJHIIJJJJJJJHHHHFFFFFFDEEDEEDDDDDDDDDDDCDDDDDDDD
@0C3
AGAAGCCCTTTTCTCCATGGCCTTTCCAGATAATCAGCGTCCACTGCTGAAGACAGACATGGAACGTCACATCAACGAGGAGGACACAGTGCCTCTTTCTC
+
@CCDDDADFDFDFGFHHJEGHGBGCHBHH@FHGGHEDBGDHIEGHIGIJH8DHGIJIJGADHIIIIGC?CEEDFFEFCD@>?DBDCBCBCCD@:A>@CCAC
@0C4
CTTATTCAAACATCAACAACAGGAGCCAGATAATTTTTTTGGTGGTACGAGGAAACCTTTCTCCAGGTGTCAGTAAGGTACGGAGTAACTTTCTAAAAGCC
+
00;(2):).9)9=14)4=12@><((=(9:3.3)93323(0(7=31').5/'59(8097).).(.(3(---(7-9=0:;(8(3'(&222(5(+(((+(+(((
@0C5
GACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTG
+
CCCFFFFFHHHGHJJJJIJJIJJIJIJJJJJJJJJJJJIJJJIJIJJJJJIJJIJIJJHHHHHHFFFFFFEEEEEDDDDDDDDDDDBBDCDCDDDDDDDDD
@0C6
GGAGCAAGCCCTAGATAGCCCCAGAGGGATGCACAGGGATGGGAACACTCTGCCATCCCCCAGCAGCTGGGACCTGCAGCCAGAACTTGCAGCTCCACAGG
+
@@@FFFFFGDAFHEDHGDHHGHIJIIIDGGFHGGGEG;?DGGGGEHIJJJDHEHIEIHHIHHFFEFCCECADBD9?BCD@BDDDCAACCACDCC@@CDC8<
@0C7
ATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAAC
+
?@?BDDDDHGHGDGIIIJJIGIHIGGHIEIJDEGGFFGGGGJDHIIJIGEEHHEF@DFAEEBE@ACD=A?ABDDDDDDCCADDDDDDBDDDDDDDCCC:CC
@0C8
TAACAGTCCAGCGGGAAGAAGGCATTTGCAGCTCCAGACTCAATTAGAACAGCTCCAAGAAGAAACATTCAGACTAGAAGCAGCCAAAGATGATTATCGA
+
=<;=72<<<<C3)1<A11@@=;15:ABA<7*0>7==7*<77>B><ABBB48..).)==;>AAA>>;>@;6;3>(;;5;=3355;====99583(3+:?98
@0C9
CTCGGCCCACTGCATCCTCTGCTTCCTGGGCTCAAGCGATCCTCCCACCTCAGCCTTTTACAAGAATTTGAAGCTGCCATTAAACAAAGAGATGGCATTAT
+
CCCFFFFFHDGHHFIGIGIJJIIIIJJGGHIIIJIIGHIJJJJJIJIJJJJJIJIJJJICEHEHHHHHFFFFFFECECEDCDDDDDDDDDDDDDDDDDDDE
@0CA
GGAATGTATCGGGAAGGACCCACATACCAACGGCGAGGATCACTTCAGCTCTGGCAGTTTTTGGTAGCTCTTCTGGATGACCCTTCAAATTCTCATTTTAT
+
@@@FDDFFHHGHGJIGGBGGIJJJIJFIGIIJJIIIIIDEEEACDDEFFFEEEEEC@;ACCDBB9>>C@C>CCDDCCCCCCCDDDDDDDDCDECDDCDEED
@0CB
CTTCAAGAAAAATTTGCACAACTTGAAGCAGAGAATAGCATTCTTAAAGATGAAAAGAAAACCCTTGAAGACATGTTGAAAATACATACTCCTGTTAGCC
+
CCCFFFFFHHHHGJIIIJJJJJIJJJJJJJJJJIJJJJJJJIJJJJJJJIIIJJJIJJJJJJIIJJIJJJJIGHHHGFFFFFFFDECFEDEDDDDDDCDD
@0CC
ATCCAGCACGCCAGTGTCCCCACTGCATCATGCATCTCCAAACTCAACTCATACACCGAAACCTGACCGGGCCTTCCCAGCTCACCTCCCTCCATCGCAGT
+
?@CDFFFFH?FHGIJJHIIGIHIIJIJJJGGIIGHJIIIJIJJJGIIIIIIIIIIJIJGIGHHHHFFDFDDBDDDDDDCCDCCDCBCDBDCCBCCDDBD@8
@0CD
TTTGAACTCAGGGTCACCACCAGCTATTGGACCTTACTATGAAAACCATGGATACCAACCGGAAAACCCCTATCCCGCACAGCCCACTGTGGACCCCACTG
+
7;=A;=32?7=C;22?AA>=AB++<?9=<:?A=@?*?:4?<????*)8*=A3?B>*877;-4:AAA>@@@==(.5(,326=(910+2(3(89(+8;<09;3
@0CE
CTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGG
+
@@@DDFFDDFHHHJIIGIIIGIJGGJJJIJJIJIJIJIJJJJIJIEHGGGIJJJJHHHHHFFFFCDDDBBDDCCCDDDCDDECDDDCDDCDDDDDDDCDDD
@0CF
AACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCC
+
@7=DDBDDFDHDHIIGGDH>HEC<FFHAB?FHEBG9B>1?DHBGHFEF7*9BFBFCH;;B@=CCGG;CHE;;@?D>AA@;>>3;@CCB<?::<CCC9A>8?
@0CG
GGAAGATAAAGTTTCTTTTGAAAATATGACTGTTGGAGAAGAAAGTAAGCAAGAACAGTTGATTTTGGATCACTTACCATCTGTAACAAAGGAATCATCAC
+
CC@DFFFFGBHHFHIJJJJJFJJJGGGJJJJJHJGIIGGHIJJJJDGGIIJIHJJIGGHGEGIJIGGDGIJJJJJEHDHHHFCEFF@DFDEEEDDDDDDDD
@0CH
TGACAAATTCAGGCAGTACTCAGCAAGGTACAACTATTCTTCAGTATGCACAGACCTCTGATGGACAGCAGATACTTGTGCCCAGCAATCAGGTGGTCGT
+
@@CFFFFFHHHDDHIIJFIHGIJFIIIG<FHGHIIJJJIJIGIJFGIIJJIJIJJJJJIIJIIIIJJIIIJJFGICHECEEF3>BEEEEEEDD;AB9C?@
@0CI
CCCTTCTGACATCTCCTACATGCCTTCCTACCATGCCCACCAGCAGAAGGTGAACTTTGTCCCTCCCCATCCATCCTCCATGCCTGTCACTTCCTCCAGCT
+
CCCFFFFFHHHHHIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJFHIJJJJJIIJJJJJJJJJIHHHHHFFFFFECEEEDEDDDDDDDDDDDDDD
@0CJ
TGAAGACAAAACTTTTGTAGCAGAAACATTGGAAATGGGTGAGGTTGTTGAAAAGGATACAACAGAACTCATGGAAAAACTTGAGGTAACCAAGCGAG
+
CCCFFFFFHHHHHJJJJHIJJJJJJJJJJJJJIJJJJJJDHGIJGGIIJJJJJJJJJJJJJJIJJJJJHHHHHHFFFFFDEEDEDD?CDDDDDDBDDD
@0CK
CCCAAGGACCCTGAGGGGGTTCCTCCTCTCCTGGTCTCTCAACAGGCAAAACGGGAGGAGGAGCGCAGCCCAGCTGCCCCACCACCTCTGCCTACCACCTC
+
@@@FDDDFGDDFHEHGBFGDDFIGGHGGIJGGGHBFHFHIEGHDGGEHGIFHGFFDBBDDDD?BDDDDDBDAB<CCCDBD@BBDDB?BDDCDDCDDDCDDB
@0CL
CACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACC
+
:=8=4=DD>FFBF@@GGII@??4F92::::9D9:D8000B9*?F30/B/?/88./8=F;58)..7CEFF2?3.933,3,,,5(5,;(,;;,,>09B582+8
@0CM
TGGCTCACTAACTAACGTGAAAGCCTTACAGAAATCTCCAGGACCTCAGCGAGAAAGGAAGTCATCTTCATCCTCAGAAGACAGGAATCGAATGAAAACAC
+
@?;DDDBAF>FADHGGEIIIIIIIAGH@FDGIIEHCGGDHGIEGEHGGGEGEEBHICCHIEHHEEAEA?ADC@B@BCCCC@9>C?BBCC?BC>CCCCA9<?
@0CN
GCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGC
+
@@@DB?DDF>FF?1AA;:A?A<+ACB=@FFGBFGE<B?GBF;;DDA@FFBCDC=E16=@D)77=A;=?CABDD3?=6;6>ABA;?@93@AABB>@:(:<8
@0CO
GACGCTGCCTGAAGTGTGCTCTGAACAGGACGAACTGGATTTCCTCATGGAAGCCCTGATCATCAGCAAATTCAACCACCAGAACATTGTTCGCTGCATTG
+
CCCFDDDFHDFHHD<CAFHHHD@HHEEGHGGBH@?BG@DD@DBFEFHGIGGI@GHEGAHICCGCEHFHFDEFFDEA>?CDDDDDDCCCCDCDDDDDDDDD@
@0CP
AGAGGAGTATGCTTGCCTTCTCAAAGTAAAAGATGATTTAGAAGACAGTAAAAATAAACAGGAATTAGAGTATAAAAGTAAACTTAAAGCACTTAATGA
+
CCBFFFFDHHHHHJJJJJJJJJJJJJEHIJJJJJJJJJJFJJJJJIJJGIJJIIJJJJJJJJIGIJJJJJGGEHIJJG=AEHGHHFFFEFFEEEEEEDD
@0CQ
CTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCC
+
CC@FFFFFHGGHFJJJIIIHGHIIIJIHGCHIIJIJGGAFHFGA;@8==@EHHGE.;BEFEFCD:ACACC@DDDDDACDDDBCDDD:A?BBB>?8??BDB?
@0CR
AGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGAC
+
@@@DFFFFHHGHHIIIJJIIJJCFHHHGIIGEHIJIJIGHGGJGGIIBHHGGIJJGIIIGHIGIJIJGHHHEDFFFFECCDEDDCDDDDDCDACCBBB;5@
@0CS
GTTAAAGATGACTGTGGCCTCCACCTAAGGGACAGCGAGGACACCTGCCCACTGAATGCTCGTTCTTATGACCCCCAAGGAGAAGGCAGGGTGGATCCTG
+
7=;<AA;++<,@,72<3;;3?A7+<=A?9A9):=;A)00=(9)8-))9>A3;>9A9>A)=.59,5;(;>(((5;(,,8((((((+((+(&0+85(+388(
@0CT
CAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAGGTCAATATAGCCAACAGAGCAGCAGCTACGG
+
CCCFFFFFHHGHHJJJJIIJJJJJIJJJJJJJJIJIJJJJJJIJJJJJJJIIII;))..==C.6(););)7((;((.(-->(;;85(((,,,,5283(+0<
@0CU
CATAAATGAAAGCTTTGAAGGTGAAGATGGCGATGTGATTTGTTTGAATTCAGATGACATTATGCCAGTTGCTTTAATGGAAACGAAGAACCGAGAAGGGT
+
@?@FBDDD?FDFFGGGI@HHIAEHGE9EC@F@8?C:??FHHH<BCEBGHGEEH@B?*==BCCGGCHCFFGGGGHGEHEHCEC@DF??A@CCBBBBBBCBBA
@0CV
CCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGC
+
1=8AB=:?DDB2A+<CAB@;EF;F>3<?EEE;DE9DFDEDDB9;8DDB>DEBCA@;ADEECCCD@DDADDDD@A>A;;A?@83,3;A;;;>>>>A:4::>
@0CW
CTGTAATCTGCCCATCAGGAATCTCCCAATCATCACTCGAGTCCCGTCTACCAAGTGTTTTCATTCGATTCCTGTCTTCTGAGGATGAAGATGACTTCCTT
+
?;14BDDDFDBBBDFGGIEGCGCBHHCCH>DGIIEECCHAB9B?FF88BDHGFHBBBB=AFCGHEGGGEAEGACEHH=CDC;@BCCCCCCCCC3@ACCC@A
@0CX
ACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCC
+
<@7DD3;BFDFB4A:::CB?@FE?FCFFIEDDDF@8/7B)8==C;84@CCE7AE7=>EDB>BD?AAA@;;;;?B-,>A(:@B(<&+4:?BBB<9A(4:<
@0CY
CCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGG
+
@CCFFFFFHHHHHIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJIJJJJJJJJIJJIJJJJHHGHHHFFFFEDEEEEDEDDDCCDDDDDDCDDDDDDDDD
@0CZ
GCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGC
+
CCCFFFFFHHHHHJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHHHHFFFFEEDDEDDDDDDDEDEEDEDDDDDDDDDDD
@0D0
CCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCAT
+
@@@DDBADFDFBFHED>F<<<CF3CFEBEFDGE9BG?19CGAEHIGCGE@EDHBFBHIIGIBGHEBBDB)6;;;6>BD@C:>8=BAAA8?@@B??>CCC:@
@0D1
AGAAGTCATCAGAATGCAAGATAAAAATCCATACAGCTTTCAGTCAGATGTATATGCATTTGGAATTGTTCTGTATGAATTGATGACTGGACAGTTACCTT
+
18+=1=?A?<DD>E<+:CEEE<B>C?E;++AA+@CFEA@<D9CDD<D<?B**9?9?BDEEAA:DEIA>DEDEI;A7)8>CCA@@C??:?CADD@DDB:@@A
@0D2
TGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGC
+
C@@FFFFFHHGHGIJIGIIGIIIIGGHIGIIIGHGGHGEHIIIIDIIGHBHGHGJJEHIGHCHIIFHCHHGDDFFFEDEEEECCBDDDDDDDCDDDDDDD
@0D3
ATGGACCACAGATTTCGCCGCCAGCTTTCTGAACCCTGTAACTCCTTTCCTCCTTTGCCGACGATGCCAAGGGAAGGACGTCCTATGTACCAACGCC
+
CCCFFFFFHGHHHJJJJJIJJIGHJJIIJJJIIJJJJJGIJJIGIJIJGIHIJIIIJJJHHEDABDDDDDDDDB@DD?AB>@DDDDCDDDDCDDDDD
@0D4
GAAGAAATGAGGGTTACCTATGGGACTGAAGGACTGCAGCAGTTACAAGAATTTGAAGCTGCCATTAAACAAAGAGATGGCATTATAACCCAGCTCACTGC
+
B@@FFFFFHHHHHHIIJJJIIJJJIJJIJJIIJJJJJJJIJJJJJIJJJJJJJJJJJJJIJJJIIJJJJJJHHGFEEFFFFEEDDDEEDDDDDBDDCDDDD
@0D5
GGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATAC
+
CCCFFFFFHHHHHJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJIIJIJIJJIGHFFFFEEEEEEEDDDDDDCDDDDDDDDDCDDDDACDDED
@0D6
CAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAAC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJHHHHHFFFFFFEEEEEEEDDDDDDDDDDDDDDDDDDD
@0D7
GGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGC
+
?@@DDDDDD;+AFFIIFBEGFFIE?F9EFBGI@FEFIF?DFBDFBGEDFIFFEE=@@E;DAAEEFF9@@?BB<BCCB>@AB@;;;AABBB??BAB?>3<
@0D8
CCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACT
+
CCCFFFFFHHHHHJJJJJJIIJJJJJJJJJJJJIJJGIJJJJJJGIGIJJIJJJJJJJIJJIGIGIIJHHHHHHFFFFFDDEDEDDDDDDDDDDDDDDDDD
@0D9
GGACAAGTGCAAGCCTATGTCCTATGAGGAGAAGCGGCAGCTCAGCTTGGACATCAACAAGCTCCCCGGCGAGAAGCTGGGCCGCGTGGTGCACATCATCC
+
BCCFFFFFHHHHHJJJJIJHIJJJJIIJJJIIJJIIJJJJIJJJIJJJJJGIJJIJJIJHHHGFFFFDDDDDDDDDDDDDDDDBDD<@DABCDDDDDDDDD
@0DA
GAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACC
+
@BCFFDDEHHHHFIIIGGGHIIIIHIEGDGIHDHGIIECGGIIJJIIEHHFGHGF@DFCEEC>CCC@ACDDBBDDB@DBDD<??CCDB@CCCDDACDDBB
@0DB
CAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGG
+
@@@FFFFDDHHGHIJI@GGIJJGEIGI@GFHHIJIIIJIGIGGIGHIJJIIJGIIIGIJJIGIHHHHFDFFFFDEEECDDDDDDDBDDDBDBACDDDEDDD
@0DC
CGCCTTTGTTGCCGCGTTCGCGGAGGACGGGCCCGGCTCCGGCCCGGGAACTGAAAGGACCTATCCAGACATTTAATGTGGATGCACCATGCCAGACCGTG
+
@@@DFDDDHHHFDE:FFGAGBGIGGIGGIEIHFDCBDDDDBDBB88BDDDDDAACCDDDDBDCDCCCCCB?ACD>:>A::CCAABACCBA>?CDC?BDD9A
@0DD
CTGTGTGAAATGCCTTGCTATACATCCTGACAAAATTAGGATTGCAACTGGACAGATAGCTGGCGTGGATAAAGATGGAAGGCCTCTACAACCCCACGTC
+
@@@BDDDEFFHHGGGGHGICIHIIIIIIIGGIHGIHGIEGIIIIIIIIIIIIIIIIIIIEIIIIIIIIEHHHHGEFFFFCEDDDDDDDDDDDDDDDDDBB
@0DE
GGAAAAAACCTGAGAACTTCCTGATCTCTCTCGCTGTGAGACATGTCTGAGACTCCTGCTCAGTGTAGCATTAAGCAGGAACGAATTTCATATACACCTCC
+
@@@BBDDDDHHGHIJIJJIIJIEHEGHIIGJJGJJGDHGJJJIIG?FGGHIIGGHGGEGGEHEDEDHFFHHGFDDDFFDDCC@DDDDDCE>CDDDDDCDBD
@0DF
CTCCCTCCATCGCAGTCCATACCAGATAGCAGCTACCCCATGGACCACAGATTTCGCCGCCAGCTTTCTGAACCCTGTAACTCCTTTCCTCCTTTGCCGAC
+
?@@FFFFDHGHHGHGEEHIJGIGIJJJIJIIGIIJGIJJJJIIGHIIIHGHIJJJJIJFGFDDDEEEDDDEDDDDDCCCDCDDDDDDDC@CCDDDCDDBDB
@0DG
GTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCC
+
@@@DDDDDHDFHHII<FHECDH;94:?FD@?FH7BFCGBDFG9DCBG>@BG>>==FCHI@;2=CA7==:B?B>B???5<(55>>C@CC/5-5<B8??88&0
@0DH
GGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGC
+
@@@FDADDBDHFHIGD@>FH>B9FEA?FFIEHG?DDFEE@F@DGGEHAAGDE=@@=37;7CAHE;A=B;6;6;A;@>5>A;C;@@::>C???A>:>@A8
@0DI
ACCGAAACCTGACCGGGCCTTCCCAGCTCACCTCCCTCCATCGCAGTCCATACCAGATAGCAGCTACCCCATGGACCACAGATTTCGCCGCCAGCTTTCTG
+
@@@FDFFFFFFHHJJGJJJJIJJJGHIEFDHHHIGICHGGIIIIGGEHFHGFFHFFFFDEEEECEDDC?ABCDDDCDBDDDDDDDCCDDBDDBBBDDDDDD
@0DJ
CAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJIIJJJJJJJJJHHHFFFFFFEEEDDDDDDCDDDDEDDDCCCDDDDDCDDDDD
@0DK
GAATTCGTCATCAAAGACCCTGATGAGGTGGCCCGGCTGTGGGGCGTTCGCAAGTGCAAGCCCCAGATGAATTACGACAAGCTGAGCCGGGCCCTGCGCT
+
7=+<2<22@2+<72?7C=+ACB+<?BBB=A7AB50?0:8/=B<<A@<@=@====5;9==?===;;;8:383:??:<;;;58;??:<??;;;-5;7;<==9
@0DL
TCTGGTTGTTACAATCCCACTGACCTTTGTCTGGCATAGAAGATTAAAGAATCAAAAAAGTGCCAAGGAAGGGGGGACAGTGCTTATAAACGAAGACAA
+
7;;=A+?+<7=C2?A=ACB37<+?>9<@+<=<@A<)*?*=AAABB9?B77)=A*=ABBAA)=>BA)5=AA;;<='&&58838:?;78::=?<;<<.38;
@0DM
CAAAAGGCCGGTGTTTGCGGACATCAGCAAAGACCTGGAGAAGATGATGGTTAAGAGGAGAGACTACTTGGACCTTGCGGCGTCCACTCCATCTGACTCCC
+
@@?DBDDDHAADFE?F9<?@?DFBGGHCGE**/?;B8B(=@@A=EG=7@ECCHEHHEE2;;AB@;CCC>ACCCCCC=:=B7>BBBBCCCC:CCCCCC:@CB
@0DN
CTGAGATGTCTACAGCACGGATTATTACAGGGTGGGAGGACACACCATGCTCCCCATTCGCTGGATGCCTCCTGAAAGCATCATGTACCGGAAGTTCACT
+
@@@DDADAFHDFFFHFHGGIAEGGGIIBGGIB?DGBHEGHEGIIIIIIGIHEGCHEFHHHEDE>>ACBACCBCC:ACCCCCCCCCDDDC9<<@BACACCC
@0DO
ATTAACCACAACAGGGCAGAAAATGTACAGTCATGTGATACTCAAGTAAGCTCTTTATTAGATGGAGTTGTGACCATGACAAGCAGGGGTGCTGAAGGATC
+
@?@DFFFFHHFFFGEIFBECGICD@FGIIIGBHGEDHHGIEHBEGG?DGHIIEGHGEHEEHCFHEGDFHEEG=D>CHHEEE@?BBEDDD;@BDDCD@C?CC
@0DP
TGAAAAGGGCCCCAGGCAGTTTTATGATGACACCTGTGTTGTCCCAGAAAAATTCGATGGAGACATCAAACAAGAGCCAGGAATGTATCGGGAAGGACCC
+
@@?DDDBDBFFFFIIGHIIHEHHEEGGGHIIJJJJIBFBFHFHIIJIIJJJGGHIGIGFHGIIHFHHHHF<BF>>@CA??@BB@C>B>C?@BBD?@B<?B
@0DQ
CGAGGATCACTTCAGCTCTGGCAGTTTTTGGTAGCTCTTCTGGATGACCCTTCAAATTCTCATTTTATTGCCTGGACTGG
+
CCCFFFFFHHHHHJJJJJJJJJJJJIJJJJJFHIJIGIJIJJJIGJJIIJHIJJJJJJJJJJJJJJIJJJJJIHHHHHFF
@0DR
CATCAACCTCTCTCATCGGGAAGACCTGGCTTACATGAACCACATCATGGTCTCTGTCTCCCCGCCTGAAGAGCACGCCATGCCCATTGGGAGAATAGC
+
@@CFFFDDFFHHDGGIHHGGEGIIJJGGIDHHEFDFGGHGIGIGHGGFHEGGGGIIEFGIJJGDBFFDECE@>@@BD6?=?>CCD@CCCDB?B@?CCDD
@0DS
GTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGC
+
@?@FFFFFFFFDDIIFGICBFGIIGCGHIJGGIIJIHGIGBHCH;@CDHGIJHEHFHF?@DDECECE@CCCDDDDDDDCCCC@@BB??BBDDDDDDCCD
@0DT
GGAGAGCACACGCGTGATCCAGCTGATGCCCAGCCCCATCATGCACCCTCTGATCCTGAACCCCCGGCACTCCGTGGATTTCAAACAGTCCAGGCTCTCCG
+
B@@FBDDFFHHGHIGIIIJJIIJJIJIIJJJJJJJJJIJJJJJJIJIIGIIJGGHHFHHHEEFFDDDBBDCCDB?BD?CDDDEDD:ADDDDDDDDDDDDDD
@0DU
CCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTAT
+
CC@FFFDDFHHFHGAHIIG?@EAEAD@CBDBGGDIDEHGEGIGE0@AHE@CHAHDBC@CACBCCC>;;@C?CDACDDD??BBDCCDDD?BDDDBBD?CCCC
@0DV
CTTTGTCAGATGAGAAATGGGATGTTATTAACTGGAGGAGGGAAAGACAGAAAAATAATTCTGTGGGATCATGATCTGAATCCTGAAAGAGAAATAGAGTT
+
@C@FFDFFHBDHHGGGAHGIIJIJCEFIGIIHIIJEEFFGIJGGEIIIIIJJJIJIIJGGIEGHGGI=EHFDEB>CDFECDC>@ACCDC?CCDDCCCACCD
@0DW
GCTCGAGAATGTCGCAGAAAGAAGAAAGAATATGTGAAATGCCTGGAAAACCGAGTTGCAGTCCTGGAAAATCAAAATAAAACTCTAATAGAAGAGTTAA
+
CCCFFFFFHHHFHIJJJHIIJIJIIJJJIJJJJJDDIIIGJIJJJJIJJIJIJGJHHIIJHFHHHFFFFFEEEEEEDCDDDDDDDDDDECDDDDDDCDDE
@0DX
CAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTT
+
@@@DFFFDHHHHGIEGGFHGGDHGGIGGGGHJIJJJIJJJIJI?FHFHIJJCGIJIIIIGGIAEHGHFHFFFEDECCEEEDCDCCD?CCACDCDDCDDCD
@0DY
AGACCACTCTTTCCCCAAATTCTCGCCTCTATTGAGCTGCTGGCCCGCTCATTGCCAAAAATTCACCGCAGTGCATCAGAACCCTCCTTGAATCGGGCTGG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHHFFFFFDDDBDDDEDDDDDDDDDDDDDDDDDDDDDDDDD
@0DZ
CCACAAACTGTGGTGATGACATCTCCTGTGACTCTCACCTCTCAGACAACTAAGACAGATGACCCCCAATTGAAAAGAGAAATAAGGTTAATGAAAAAC
+
@@CFFFFDFFDFFCFGCBGAHIGGGHIDHIICGG@HGHGEFGGEH<DHHIBDFGHEHIHGCGIGGGAGHEHGHHFDEFFCCE@CDDD5>CCACDCCCDD
@0E0
GTGAAATGCCTGGAAAACCGAGTTGCAGTCCTGGAAAATCAAAATAAAACTCTAATAGAAGAGTTAAAAACTTTGAAGGATCTTTATTCCAATAAAAGTGT
+
@@BFFFFFHHHHHJJJJJJJIIHIJJJJIJJJJJJJJIJJJJJJJJJJJIJJIJIGIIGHGGIIIIJJJIHHHGGFFFFDEEEEEEEDEEEDDDDDDD:AC
@0E1
AATCACTGCCCAGCGTCCTCCGAGTCCCACCCGAAGCCATCCAGCCCCCGGCAGGAGAGCACACGCGTGATCCAGCTGATGCCCAGCCCCATCATGCACCC
+
CCCFFFFFHHHGHJJJJJJIJJJJJJJJJJJJJIJJJJJJIJJJJJJJJHFDDDDDDDDDDDCDDDDBDDDEDDDDDDDDDDDDDDDDDDDDDDDDDDDDD
@0E2
GGGAACTCCGGGACCCTTGGGTGTGGAGAGGAGAGGGTCTGGGAAGGTTATAAACCAGGTATCTCTACATCAGGATGGCCATCTAGGAGGCGCTGGGCCTC
+
CCCFFFFFGHHGHJGIIJIIJHHDGIIJGGGHICHJJBFGHIJJJJJCEEEHHHFDFFD@CDEDEEDCDCDDCDDACBDDDDDCCDDCDDDDBDDDDBDDD
@0E3
CTCGGACTCTATTGGGCCCCAAATTCTCACCAGTCCGTCTCCTTCAAAATCCATTCCAATTCCACAGCCCTTCCGACCAGCAGATGAAGATCATCGAAATC
+
????BDDDBDDADE:E+C@F?F3*?E4?*9C@DECDDB28B*8?DDD@>BDI<B;C;;A@D;=C776;A7=?>;<@??:=9395>>>A3,5::>AAAA8<(
@0E4
AAAAATTCGATGGAGACATCAAACAAGAGCCAGGAATGTATCGGGAAGGACCCACATACCAACGGCGAGGATCACTTCAGCTCTGGCAGTTTTTGGTAGCT
+
CCCFFFFFHHHHHJJJJJJJJJJIIJJIJJJJJJJJJIIIIJJJIJJJIJIJIJJJJJJHHGHFFDDDDDDDDBCDDDDDDDCDDDC?@CCDDDDDBCCCC
@0E5
AGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTGAGTTGCTAAGAGAGAAAACCAAATAAGAATGAATGTGTTTAGAGTT
+
;@@?A+AD?<DA<A<2C?:I?BHID<AC1?:91::B?GG;9D68D@@A=88).)8.7.7)..77777?D(77;>?=?B;5@:@>:A(55:,,,,9;>4:+4
@0E6
TATTAATGGAAAGACTCAATCAATCTGATTCTATAGAAGACCCTAACAGTCCAGCAGGAAGAAGGCATTTGCAGCTCCAGACTCAATTAGAACAGCTCCA
+
;??D?DDD?FBDHBDAGBHG@F@HHCH4FHEEEB<:?F>;?DC;FB0:F90B?D@;??F8.BFFHIFAD@C7@EHHECA@>=;?>;@@CAACCC5?>@@A
@0E7
TATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCC
+
CCCFFFFFHHHHHGIIIJJJJJJIJJJJIIIJJJJJJJJJJJJJJJJJIJJIJIIJJIJJIIJIIIIJHGFFFDDDDDDDEDDDDDDDDDDDDDDDDDDDD
@0E8
CAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGC
+
@@<DDADDDHFDFGGGHDB@?CFGEGEHGGGHIIEHGHIEHHIGGGGGHEHIIGIGEH>FGGGIIGHHE?=?C@BCCCCACC@CCCCCCCCCCC>AADCB
@0E9
GAATAATCACTGCCCAGCGTCCTCCGAGTCCCACCCGAAGCCATCCAGCCCCCGGCAGGAGAGCACACGCGTGATCCAGCTGATGCCCAGCCCCATCATGC
+
CCCFFFFFHHHHHJJJJIJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJHFDDDDDBDBDDDDDDDDD@BDDEDBCDDDDCDDDDDDDDDDBDDCDDD
@0EA
CTCCTGTGACTCTCACCTCTCAGACAACTAAGACAGATGACCCCCAATTGAAAAGAGAAATAAGGTTAATGAAAAACAGAGAAGCTGCTCGAGAATGTCGC
+
?8?BBBD;2=??<:ACE?;<:+3++<A++CEE9CEEI>B?1*:?@DDDEDDECB@6B;8==@>;).=@>=;CC>=?66;AA@A?A:AA:35389=(5::(8
@0EB
AGCAGCTTGGAGTTTGTCTGCTGAATGAACCCCAATACATTATCCTGGAACTGATGGAGGGAGGAGACCTTCTTACTTATTTGCGTAAAGCCCGGATGGC
+
CCCFFFFFHGDHHCGHIIJJIIJIIIGGJGIIJJJJJJJJGIJJIJIJIIJJJGIII@HGIHHJEEHFFFFFEEEEEEEDEEEDDBDDDACBDDDDDDDD
@0EC
AGCAGAAGTTACAAATTACAAGATAAAACTTGAAATGTTAGAAAAAGAAAAGAATGCTGTGTTAGACAGAATGGCTGAATCACAAGAAGCTGAATTAG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJIJJIJJJJJJJJJJJIJJJJJJJJIHIIJJJJJJJJJIIJIHHHHHFFFFFCEEEEDDDDDEDD
@0ED
CAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATAT
+
CCCFFFFFFHHHHJJJJGHIJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHHFFFFFFEEEEEDDDDDDDDDDDDDDDEDEED
@0EE
CTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATG
+
@?<DDDDDFFFHHIIGIIIFIIIIIIIIHIGEIIGIIGGHGIIIEHIEEIIDHCFHBHEFE;BCECEEECDCCDCCCBCCB:ACCCCBBBBCCCCCBB@CC
@0EF
CAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATAT
+
@CCFFFFFHHHHGJJJJHJJJJJJIHIGHIJJJJJJIJIIJHIJJJJJIJHIGIIIIJJJJJJJHHHHCFFFFFEEEECDDDDDDBDDDDDDACEDEED
@0EG
CCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTTATGGG
+
1?@FDDDEFHHFHIIIGIIFHGIIIEFIG@HHEEDHGGDHGGFCDHIGEGIAAF=FHHDGDEHFEHE>49AA?ADD@DDD??CC@CCEDDB>>9?ACDCCB
@0EH
CTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGC
+
CCCFFFFFHHHHHJJIJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJIJJJIJJJJJJJJJHHHHFFFBEFEEDEDEEDDDDDDDDDDDDDDDDDD
@0EI
CCTTGGTGATTTAAGGCGGCAGGTTAAACTCTTAGAAGAGAAGAATACCATGTATATGCAGAATACTGTCAGTCTAGAGGAAGAGTTAAGAAAGGCCAACG
+
CCCFFFADDHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJHEHGGHHHHFFFFFFEFEDEEEDDDDDDDDDBDCDDEDDDDDDDDDDDD
@0EJ
AAATCAGCAAACAAATCAAAGCTCATGATGGCAGTGTGTTCACACTTTGTCAGATGAGAAATGGGATGTTATTAACTGGAGGAGGGAAAGACAGAAAAAT
+
CC@FFFFFHHHHHIJJIJJJJJIJJJIGHGJJGIIIDGIIIIIJJJIFIHGIJIGJHIGJJJJJJHIJJJGHIJIHHHHEHF;BBDDDDDDDDCCCDDDD
@0EK
CTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGT
+
CC@FFEDFFHHHGJIJJIG>FIIIGBFHD@;EHEG<?8?D6BBDFHEEHIDHJJIIIA>FHHHIIIGHHEB>B>B?(;@CC@ACB9?B8?<8A3::C:C>@
@0EL
CTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTC
+
@<@BDDDBFDBHFFGIEAA>HCHGDGFHHHIGHGHIG<<FGDF@FBBFGIGDHIGECEIIIGEHCEEH:?H>?ABDDDECCCCCCBAAB?CCBCCBCCCCE
@0EM
TAAACTTAGCCGTTCACTCCGCTATTACTATGAGAAAGGAATTATGCAAAAGGTGGCTGGAGAGAGATATGTCTACAAGTTTGTGTGTGATCCAGAAGCCC
+
@@@DADDDHDFDF@FAFHI@?FF<FEHICG>FHI<DFG>HIIIIIICHHCHCCCB?@FGGHI>EEHADDDBA>>A>;@@6;@C?=;=,93>AACCCCCCBA
@0EN
CCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCCGTTACTC
+
;+:AB1+ACC4+2AA;AABAC>;2A1??B91:D<DD8BD<D>DDDD;DDCC<38=AC@).7.=7.7).)=7?>@?',9;>5;AD>AA>AA:A>(5)0<?>A
@0EO
CTCGATGATAGTATTTCTGCTGCAAGTACTTCTGATGTTCAAGATCGCCTGTCAGCTCTTGAGTCACGAGTTCAGCAACAAGAAGATGAAATCACTGTGCT
+
CCCFFFFFHHHHHIJJJJJJJJJJJJHJJIJJJJIJJJJJJJJJJJJJJJJJJIJIJIJIIEHHIJJIIIHIJJJJHHHHHFFFFDEEEEEEDDDDDDDDD
@0EP
CCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGT
+
?@;BBADF?FFBHIIIGGGIDG?GDFEGIEGGIHHIIA=BFHIFGIGHGHDGH=CHHFFC>@CDC@CEEDC?@55>CAAB???:AACDDBBD<ACACD<<@
@0EQ
ACCAGATAGCAGCTACCCCATGGACCACAGATTTCGCCGCCAGCTTTCTGAACCCTGTAACTCCTTTCCTCCTTTGCCGACGATGCCAAGGGAAGGACGTC
+
@@@DFDFFGHHGGFIJIJJJFGFGHGGIIJHIIFIIIJJIIIJJIIIGHGIIIIIFHHHHHFFFFFFEEEEEECDCCCBBDBBBBDDCDDDDBBDDABB9>
@0ER
GCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCC
+
@CCFFFFFHHHHHJJIJJJJJJJJJJJJJJJJJJIIJIJJJJJJJIJJGIIIJJIJJJJIJJJJJJHHHHFFFFFEEEDDDDDDDDDDDDDDDCDDDEDED
@0ES
CCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATAC
+
?@BDDDFFFHFHGJJJIIIJJJJJIIJJGIAEH=FGGAHGHHGJJIJIJJIHCCHCG;AHHHGFFFFEEECEEDC@>>@CCDDDCCCADBBDDDDDDDDC
@0ET
CAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGG
+
CCCFFFFFHHHHHIIJJIIIJJIJIJJJJHIJJJJJJIGIIJJJJIIJJIIJJIIJJJJJJIJFAECECFFFFEEEDDDDDDBDDDDDDDDBCCDDDEDDD
@0EU
GCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJGGGGJHGHHGHFFFFFDDEEDDDDDDDDCDDDDDDDDDDDD
@0EV
CCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGG
+
CC@FFFFFHGHHHIIGHGIGHJJJGIJGHIFHIGIJJIJJJEGHGDEHIJDIBBFCGHGHJJIHHFFFBCDFCCEDE>@BDB8<ABA<?B9B?:CCDA>@A
@0EW
CTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCC
+
@@@DDDD?FDFFHBFHI<F;E=FCG<F?D?DGHI?FGGIDHGGD@F;@@GAC?=C77@?CCDCCCAA3>3=5=>::>CCCC>@@CCCBB18?BBBBBB>BB
@0EX
GCTTTTTTTATTCTCTTCCACTTCCTCTTTCCTTTTGTGCTTTTCTTTTTTCTTTTCCTTCTTGTCTTTCTCCTTTTTCTTTGGTTTGTTCTGCTGGGGCT
+
::??;;D<FHBADGBE?EBHB9?3CDHB9?DDFFE@F:0*09B@??BFG@;F;4;=F4=C:=CE3)=;)=?B7.;BB;>@CC>3;,;??AC@:(5((,&&&
@0EY
GGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACAC
+
CCCFFFFFHHHHHJJJJJJJJJIJJIIJHIJJJJJJJJJIIJJJJIIJJJJJJJJGIGJIIJIJJHIIHHHHHFFFFDDDEEDDDCDDDDDEEDDDDCDD
@0EZ
TTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGC
+
?@@DDDEDHGHDDGIHFBHIIIJJI<FFGGEC;EF<FHC@DGE=@DAFFHGG;=@FGGGHGEHAE?7??CB;?C@;@ACCCD=5?>?B>:;>>?A<5@?<8
@0F0
CAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGG
+
=7:7?AAAA<BC<CBB3+++33+<+AAB=<BAB>=*?17AA*:7?=*9==25(((9)/==A;)..=>3()7)7=>>>@1((,6;=6=?(:9(+4((+8(5(
@0F1
CGCCAGTGTCCCCACTGCATCATGCATCTCCAAACTCAACTCATACACCGAAACCTGACCGGGCCTTCCCAGCTCACCTCCCTCCATCGCAGTCCATACC
+
?1=DDFDDDFFHBGIEGIGHI@CHHHIFIIEIGICGGGEHDHHIIICHEHIIGIIIG@HGIGDDA?CCDDDCDCDCDBC?B@<CDCCDBB?@8?CCEDDD
@0F2
ATACATCTCATCCAGCTCTGCCCGGAGTTGTTCTAACTTTCTTTGTGTTTCTTGTTCCATTCGTTGTACTATATCAGTTTCGAACTGGCTGTCTTTATGAT
+
@@@FFDFFFHHFHGEBHHEHIGIIIGGGDCDDHDDH@FGDGGIIIDAHHIEHIBHIIIIIHGGGI@;DEHGAEECHECHFCEFECDECDDDDDCCC>@:>C
@0F3
CCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAG
+
@C@FFDFDFHGHHIJJJGIJIIIGIIIIBHIJJJJIIIII?BFHIJGJHIIIJJGJJJJJJJJJIHHHHHHFFFFDDDDDDDDCDDDDDDDED
@0F4
CTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTAT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJFHIHJJJJJJHEHHHHFFFFFFEEEEDDDDDDDDDDDEDDDDDDDDDDDDDDDDDDDDDD
@0F5
AAATCATAAAGACAGCCAGTTCGAAACTGATATAGTACAACGAATGGAACAAGAAACACAAAGAAAGTTAGAACAACTCCGGGCAGAGCTGGATGAGATGT
+
CCCFFFFFHHHHHJJJJJJIIJJJJJJJJJJJJJJIIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHHGHHFFFFFEEDDDDDDBDDDDDBDDDDDDDD
@0F6
CTCAGCAAGGTACAACTATTCTTCAGTATGCACAGACCTCTGATGGACAGCAGATACTTGTGCCCAGCAATCAGGTGGTCGTACAAACTGCATCAGG
+
CCCFFFFFGHCFHJJJJIJJJJJJJJIIJJJJJJJJJJJJJJJJJJJJJJIJJJJJIJJIJJJJJJJJJJJJJJJCHHEDFFEDDEDDDDDDDDDDD
@0F7
CAAACAAGAGCCAGGAATGTATCGGGAAGGACCCACATACCAACGGCGAGGATCACTTCAGCTCTGGCAGTTTTTGGTAGCTCTTCTGGATGACCCTTCA
+
CCCFFFFFHHGHHJJJJJIHIIJIIJJJJJJJJJIIJJJJJJJJJJJJFFDDDDDDDDDDDDDDDDDDDDCDDDDDDBCDDDDDDDDDDDDDDDDDDDDD
@0F8
GCTTCATTTGCAAAGAATAAATCCAACTACAGTGAAAATGAAAAGTTCTGTCTTTGATGAAGACAAAACTTTTGTAGCAGAAACATTGGAAATGGGTGAGG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJIJHIIJJJJJIJJJJJJJIJJGIJJJIJJIJJJJIJJJJJJJJJEHIJJJHHHHHFFFFFFEEDEEABDDD
@0F9
CAGCTTGCAGCCCTCTCTCAGCCCCAGCAGAACAAACCAAAGAAAAAGGAGAAAGACAAGAAGGAAAAGAAAAAAGAAAAGCACAAAAGGAAAGAGGAAGT
+
@CCFFFDDHHHHHIEHGGGEGIIJJJJJJIJJJJJJIJJIIGIIIIGIIEGGIJJJIIIHGFGHFFFFEDEDDDDDDDDDD?ACCDDDDBDDDD>CBAAB>
@0FA
CTGGGAGATCTTCACCTATGGAAAGCAGCCATGGTTCCAACTCTCAAACACGGAGGTCATTGAGTGCATTACCCAAGGTCGTGTTTTGGAGCGGCCCCG
+
???:+=A1?DD?BBE?@EE++ABCBEFDD=EEA@?CB>CDD??<BD>?D@DD>0@65@A;CCEADAC3??;?37?;==66',,599996:35&)55;3&
@0FB
CTGATGTTCAAGATCGCCTGTCAGCTCTTGAGTCACGAGTTCAGCAACAAGAAGATGAAATCACTGTGCTAAAGGCGGCTTTGGCTGATGTTTTGAGGCGT
+
@@@FFDDFHHHHGGHGIBHEIJJEHIIGIHECGCEHIGGEHIGDGBGHJICHIIIJ>FGGGEHIEE@CAEGFHEFFD>>BBCCA(:<1>@>ADD<??C7<>
@0FC
TGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCT
+
@@@FFFFFHHHHGIJJGIJGIJJJJJJJJJJIIIJGHIJJJJDIIJJJGHGIGHGIJGIIJIIJGGHGHHEHHHFFFFFFEEEECDDDDDDDDDDDDCCDA
@0FD
GAAGGCAGGGTGGATCCTGATCTGTCCAAGCCTAAAAACCTTGCTCCTTTACAAGAGAGTCAGGAGTCTTACACAACTGGGACTCCCAAAGCAACATCTTC
+
CCCFFFFFHHFFHIJJIIIGIJJJJJJJJJJJJIJJJJJIJJJIHJJJJIJIJJIIJGICDHIHHHHHFFDDFFED?CCDDBDBDDDDDDDDCDDDDDDD@
@0FE
CAAAGCTCTCCTGCTGCTGACCAAAGAGGACTTTCGCTATCGATCTCCTCATTCAGGTGATGTGCTCTATGAACTCCTTCAGCATATTCTGAAGCAGAGG
+
CCCFFFFFHGHHHJJJJJJIJJJJJJJJJIJJJJJIJJJJJJJJJJJJJJJJJIJJICGHJJIJJJJJHHHHHHHFFFFFFEEEEEEEEDEEDDDDDDDD
@0FF
CCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATG
+
CCCFFFDDHFDFDIIEGIICHGIIDDHIGIGHBFHIEHGGGEHEIIFHHGGEEHG<FHEIGGGHHHE@BD@ACEDB@BCBB@?BB???BDDBDDDCDDDED
@0FG
GGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCC
+
@@@FDDDDHHHHHGHGIJJJJJJEHIIGIJJGIGIIH?DGHIJJIJIIIGGHJJCHJ8@FGIGHGCEHEHDFFFDEEEADDDDB@CCC@ACDDDDDDCDDD
@0FH
ATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATG
+
@@@FFDBFFHHGHGIJIIIIIGGFGBFHIGIGHFEHGIIIJGJIIIIJJIJJHIIGHIGHIGGIGHHFHHFF??BAABDCDDDDDCD?CDCCCDDDDDDDD
@0FI
TTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCC
+
CCCFFFFFGHHHHJJJJJJJJJJJJJJIJJJIJIJJJJIGHIJJJJIJJIIIIJJIJJJJIJJJFHHHFFDDDDDDDDDEDEEEEEDDDDDDDDDDDDDD
@0FJ
TCCAGGACCTCAGCGAGAAAGGAAGTCATCTTCATCCTCAGAAGACAGGAATCGAATGAAAACACTTGGTAGACGGGACTCGAGTGATGATTGGGAGATTC
+
CCCFFFFFHHHHHJJIJIIIIIJJIGIJJJJJJJIJIJJJJJIIIGIIJIIIIJIIJJJJJJIJHHHHHEEFEFFD@BDDCBBB>ACDDDDDDDDDDDDDD
@0FK
GTCCTATGTACCAACGCCAGATGTCTGAGCCAAACATCCCCTTCCCACCACAAGGCTTTAAGCAGGAGTACCACGACCCAGTGTATGAACACAACACCATG
+
@@CFFDFFFFHHHIJGIJJJHIGJJIIGGJJJJJGIJJJJJJJJJJJIGGIJJDIGIJJBHGHHHHFECBDCCEDBDDDDD:@;;CCCD@@CDDBBDDDDD
@0FL
GCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCC
+
@@@FFFFDHHFHHJIJJJJIJJGIIDIJJIJDGJIJIJJEGGIIIIGIIIGIJHHHHHHHDFFEFFCEDCEDDDDDDDDDDDDD5<ACCDDDDDDDDDDDD
@0FM
CCATGTATATGCAGAATACTGTCAGTCTAGAGGAAGAGTTAAGAAAGGCCAACGCAGCGCGAAGTCAACTTGAAACCTACAAGAGACAGGTAGTAGAACT
+
@@@DDDDDFHDHHIGBBEFF?<ACB<CH:C:AEHH;CC1:CGIIIICHEHIIGFG:<AAG8=BCA@CCCCCCCCCCB:A?CC:??CCCCB:>C>:@CCAC
@0FN
CAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGC
+
BC@FDFFFHGHHHJJIIJJIIIIIIJJCGIJJJIIJJJGGHIJGIIJIJJJIJJJJJJJIJGIJJJFHGHHFFFFDDDDBBABDDDDDDDDDDDDDCDDDD
@0FO
GGCCTACATGCCGGAAGGGGGCTGCTGCAACCCCCACCCCTACAACGAAGGCTACGTGTATTAACACAAGTGACAGTCAAGCAGGGCGTTTTTGCGCTTTT
+
<@@DDDDDHDDAHDCCG<FHIIF?6BDEHIHEHHH4A;@EEE@;B@ACCABB@>C?9??CDEEECCABBBC<@C@>:>AC>3<<AB@BBBBBBBCB<@BBC
@0FP
GAAAAATTCGATGGAGACATCAAACAAGAGCCAGGAATGTATCGGGAAGGACCCACATACCAACGGCGAGGATCACTTCAGCTCTGGCAGTTTTTGGTAGC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJIJHIIJJJJIJJJJIJJJJJJJHHHHFFFCDDDDDDDBDDDDDDDDDDDDDDDDDEDDBDACDD
@0FQ
AAGGAATCATCAGTTACAGCAACTCCACCAAGTGAAAATAATAAACTTCAGAAAGAACTCAATGTACTTAAATCAGAACAGGACTTGCTTAGAGACCAAGG
+
-(7>14=<<:8>)=8?)))=7718))3)8:853.=):);)2:)0):9)=88>)7.)9>>>?@;)9==>9=8;89:?<;;999><<;;8=;(69=375((6(
@0FR
AGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACT
+
C@CFFBDDHHHHHIJJJEIIJICIJGGIJIFICHIIGIGGHGIJIJJIJJJJJIIJIGCEGIGG@HGCBCEFFFEECECBCCDDD?<A@BD<????BBCBD
@0FS
AGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCC
+
CCCFFFFFDHHFHJIJJIJJJJGHIJIJJGHIIGJIIJIGIIIJIIIJJJHHHHHFEFFFFEEEEEBDDDDDDBBDDDDDCCDDEDDDCDDDDDDDDDDD
@0FT
GTTACCTATGGGACTGAAGGACTGCAGCAGTTACAAGAATTTGAAGCTGCCATTAAACAAAGAGATGGCATTATAACCCAGCTCACTGCTAATTTACAAC
+
@C@FFFFFHGHHHJIIIJIIIIIGIIHJJJHIIJIJHIIIJIJJJGJIIJJJIJJJJIJJJFHGIJIIIJJJHFHFHHFFFFEECEEEDDDDDEEDEDDD
@0FU
TACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTT
+
CCCFFFFFGHHHGJJJCGIJJIJFJJIJJIJJJIIIJJIJJJDDHIJJJIJJJJIGIIIJGGIIJJHHHHHFFFFEEEEEEEDDDDDDCBBDDDDDDDDE
@0FV
CAGTGACCTGAAGGAGGTGCCGCGGAAAAACATCACCCTCATTCGGGGTCTGGGCCATGGCGCCTTTGGGGAGGTGTATGAAGGCCAGGTGTCCGGAATGC
+
@??=DDD?CDCAFHFGE2AFCF@??FH<GCFEEHIGI;CFCH=D4(:<59>A>;;??CCC@BBB>>A>CB925@<?:@CD:CCCBB?@84:+4@?B@<74@
@0FW
CGGAACTCGAGTGATGATTGGGAGATTCCTGATGGGCAGATTACAGTGGGACAAAGAATTGGATCTGGATCATTTGGAACAGTCTACAAGGGAAAGCGGC
+
(-;(8=><?98<<):981=97(;=(6>>@>1.9=)1398?;89:>1<=)3<7=??;>=>;));=>>91699939=88)=09=(:(-(:;;(7;;55(38:
@0FX
AGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACC
+
@@@FFDFFGHHHHJGGJJIGIIJEHGHIJJGHIGGIIIGIGGEGJIBHGIIJHFGFFFFFDECCEEEDCDDBBDDDDBDDDDDDCDDDBCCDCDEDCDDDD
@0FY
ATCACTTAGAGCAACTCAACCAAGTGAAAATGATAAACTTCAGAAAGAACTCAATGTACTTAAATCAGAACAGAATGATTTAAGGCTACAGATGGAAGCCC
+
CCCFFFFFHHHHHJJJJJJJJJJJHHJJJJJJJJJJJJJJIJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHHHHFFFFFEEEEEEDDDDDD
@0FZ
GTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACA
+
@CCFFFDFDFHHHIIIJIGGGIIGFEIGIJIIGIIJB<FBCIIIIDG@F>DGIH=CHDGIIIIBGHIHCEFEDE<BEABD?A@DDDDBCDAC>CCDD?C
@0G0
CCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAG
+
@@@F?DFFDADHA>FHBEHIGIGIIGGIIEHIGIHGGCHI@AEIDGHHGBBFAHIIFHGIHHA;CA?EEHDFFDCEECECABBCBBB?C>ACDCCDCCC
@0G1
CTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTAT
+
CCCFFFFFHHHHHJIJJJJJJJJJIJJIJIJIJJJJJJIJJAHIIJGIJJJHCEHHHFFFFFFEEEEDDDDDDDDDDDFDDDDDDDBDDDDDDDDDDDDDD
@0G2
GCCCAGTGACGAGTTACGCTTCCTCGACGCCACTTCATGTTCCAGTGCCTCGAGCGCTCAGGATGGAGGAAGACTCGATCCGCCTGCCTGCGCACCTGCGC
+
<<=A<=AA+2???<+@478?7)@<=A8=AAAAAABABBBAB>=A=.8>>7=:4''9/539>;;5;5(5,;9=9=9?72;9089802(8;89;;;;5998;.
@0G3
TTCAAATCAATGAACTTCAAAAAGAAATTGAAATACTCAGACAAGAAGAAAAAGAAAAGGGTACACTTGAACAAGAAGTTCAAGAATTACAACTTAAAAC
+
CCCFFFFFHHHGHJIJJJJJJJJIHJJJJJIJJIJJJJIJIIJJIIJJJJJJJJJJJJJIJ@CFHJJIJJHFHHHFFFCFEEEEEDCCDDDDDDDDDDDD
@0G4
ATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCA
+
CC@FFFFFFHHGHEGGEIGIIJHHIJJIIGCGHIJJJIJIJIGIIIGIGGHJJFIJGIHGIJIIJIHHDFFFCEEDEECDDDCCDCDDDBDDDDDDDCCD
@0G5
GGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCAC
+
CCCFFFFFHHHHHIJJJIJJJJJJJIIJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJIJJJJHHFFDDDDDDEDDDDDDDDDDDDDDDBBDDDDDD
@0G6
GAGCAGGGATGACGTAGCCCAGTGGCTCAAGTGGGCTGAAAATGAGTTTTCTTTAAGGCCAATTGACAGCAACACGTTTGAAATGAATGGCAAAGCTCTCC
+
;@@DDDDD??CFAGFGIBGIGGG>>FBFH?11?10:?DDEHIEHDEB?D>BFCFEH@A>CEGGCCE@>:=ABBDEC@@>=CCC3;>C@CA(:@ACCCCC@?
@0G7
ATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJIJJJJJJJJIJJJJJJJHFHHGFADFFFEEEEEDDDDDDDDDDDDDDDDDDDDDDDEDDDDDDDDDD
@0G8
CAAATTCTCATTTTATTGCCTGGACTGGTCGAGGCATGGAATTTAAACTGATTGAGCCTGAAGAGGTGGCCCGACGTTGGGGCATTCAGAAAAACAGGCC
+
CCCFFFFFHHHHHJIJJJJJJJJIJJJJIEIGIJJJJJJJJJJJJJJJJJJJJJJJIJJIIIJGJJAEFGFFDDDDDDDDDDDDDDDEDDDDDDDDDDDD
@0G9
AAAAAGAAAAGCACAAAAGGAAAGAGGAAGTGGAAGAGAATAAAAAAAGCAAAGCCAAGGAACCTCCTCCTAAAAAGACGAAGAAAAATAATAGCAGCAAC
+
@CCBDDBDFDDHHIIGIGCGGBHBGHGIIDHIIBDDDDHIIFGGIGGG@6=CCCECHEEB>DFCEECCCCCCCCAC?B?=@@B@ACCBCCCEECCCCBAAB
@0GA
AGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGC
+
@BCFFFFFHHHHHJJJJJJJJJJJJJHJJJJJJJJJJJJJJJJJJJJJJJJJHHHHFFFDFFFEEDEEEDDEDDDDDDDCCDDDDDDBDDDDDDDDDDDD
@0GB
CCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATGACATCTCCTGTGACTCTCACCTCTCAGACAACTAAGACAGATGACCCCCAATTGAAAAGAGAAAT
+
@<@DFFFDDHHDGGIIGGHGGGGEFGIGF>CEEBFAFHIIIIGGHJBB?F>GGFHIIGHGEHIEIIAGIGHIIJJFEEEHFEFFDCBDDDCCCDDDDCCCD
@0GC
TGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCT
+
@@@FFFDFHHGHHGIGJJFHIIGIJJIJIJJIJIHIJIJIIGDFHIJGIJJJJJJHHHGHFFFFFDD?@CDDBDDDDD>?CCDDDDDEEDDDDDDDDDDD
@0GD
CTTTCTGAACCCTGTAACTCCTTTCCTCCTTTGCCGACGATGCCAAGGGAAGGACGTCCTATGTACCAACGCCAGATGTCTGAGCCAAACATCCCCTTCCC
+
<??=;DBDBH<1CB<AEF94:FHEHIACADHH<B?FGA?FD7(8BF(7CGG55=6=5',57));;6(.(5=?:@;<C3>CDA:>@ACCC?<A:C<?3<<99
@0GE
ACTCATTGTACCCATTCTAATCGCAATGGCATTCCTAATGCTTACCGAACGAAAAATTCTAGGCTATATACAACTACGCAAAGGCCCCAACGTTGTAGGCC
+
1:=BDFFFFHHHHGJJFJJIIIHIJGIGIIIJJGIIJIEGEC>FGFIGI?FFGEGEAE4@DGGEAE:>ADDDFB:;>?>@DD?9?B<=@B??19??@CCCC
@0GF
CGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCG
+
@@?DBD@BDHDAD;FEE<C@HG@???@BB??GDFHD@@F;;@EHDHHABDCC@@@A;A>@CCAC@CCBBA>>>:>@B95-<<<<?<AACCD@CC:>@ACC5
@0GG
CAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGC
+
>=<A;2A@<7+7<C@+22@3<<C7?771?@=7AB54:08=BBAA;>/87>8.>>;=8A=;737>7>.77)..7>5>(6>;;;;;;5555;:>?=50;;5;;
@0GH
GGACGGTTTCGCCGGCAGTCTCGATGATAGTATTTCTGCTGCAAGTACTTCTGATGTTCAAGATCGCCTGTCAGCTCTTGAGTCACGAGTTCAGCAACA
+
C@@FFFFFHFHAFHGGIIFHIJJHJIJIJIGIIIJJJJIJJJJJIGEHJJIIDGHHHHHHHFFFFFDDDDCDDDDDDDDDDDCCDDD@DBDDDDDDDAB
@0GI
GCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGG
+
C@@DFFFFHHHHHJGIIIJGHJGIHIIJJGHIIGHIJJIFDHIGHJIJIJJJJGHGHFFFFFEEEEEEDDDDACDDCDCDDEDDEDDDBDDD@ACCCCDD
@0GJ
CGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCG
+
@@CDDDDDFDFHHEHGGHGGCDHBFHIHIBHGGHEFIFEGHHGIDHE:BDFDEEEDECCCCCDCDCDDDDDCCC:>@BD<??BBBDDCCC3:@@CC@CACB
@0GK
CAGATTTCGCCGCCAGCTTTCTGAACCCTGTAACTCCTTTCCTCCTTTGCCGACGATGCCAAGGGAAGGACGTCCTATGTACCAACGCCAGATGTCTGAGC
+
@@CFFFFFGHFHDIJIJJIIIIGGGHGHIIGIJHIGHIIJIIIHJIIGJJJIJIHBBDCEDEDDD?DDDBAB??BDDCDEDDCDDB@BDD@ACCADCCACD
@0GL
CCCCACACCATCCAGCACGCCAGTGTCCCCACTGCATCATGCATCTCCAAACTCAACTCATACACCGAAACCTGACCGGGCCTTCCCAGCTCACCTCCCTC
+
CCCFFFFFHHHHHJJJJJCGIJJIJJJJJJJJJIJJJJJJJJJJJIJJJJJIIJJJJIJJJIIIHGHFFDDEDDDDDDDDDDDDDDDDDDCDDDDDDDDDD
@0GM
ATCGACCTTTCCTTTCTATCCCCAACCACCCCTCAACCCCTGTTTTCCCCTGCCTTCCTTGCAGAGGCCATGGAGGACGAGGAGAGACAGAAGAAGCTGG
+
@@CFFFFFHHDHHJIGIIHJJJJJJIIJJJJJJJJGHIGIIHFHIIGIJEAGGIIIEIGHHHGH>DDFDDCEECDDBDD6?B<B?BDCCDDDDDDDCDDD
@0GN
CTATCCACACTGCAGATTATTGGACTTGGCACTTTTGAGCGTGGAGTAGGATGCCTGGATTTTTCAAAAGCAGATTCAGGTGTTCATTTATGTGTTATTG
+
@@@DDD;BDFDFHAFEDG<IFGI>EFAEG>CEFHIIIDHEHDGI@FFHIIBFECFGDGCGIIGG;@CHHEAHE;?@EBCA>C@@>DDDEBDC5>@C@CCC
@0GO
ATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCA
+
@@@DDAADDFFFFEE:<FHDHHEBDHGHIII@DDGGIIIHE@G?BCHCEHIICBEGEHDDEEA;;ACCCCBCCCCCA@CCCBBCA<9?BBBBCCCECBBC
@0GP
AGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGG
+
@@@FFFFFDHHHHGIGGIICGEHBHGFHFIEGHIHGIIEHCHIIJIJIGIIJJIGIGHHIEIIJGCCEHHEDECDDDDCCDCDDDA@BDBC@4:ACDDDCC
@0GQ
CCAGCCCCTACTGAAAAGACACCCCACTCAGGAGCTCAACTTGGGGTCCCCAGGGAGAAACCCCTAGCTCTGGGAGTAGTTCGACCCTCACAGCCTCGTA
+
CC@FFFFFHHHHHJJJJJJJJJJJJJJIJJJJIIJJJJJJIJJJJJFHIJJJJJIHHHFFFFDDDDDDDCDDDDAD@CDFEEDDDDDCDDDDDDDDDDDD
@0GR
AAATTGGGAAAGGAAAGAGCGTTGGGGGAATAAGGAGCGAGGGAGGACCAGGGGGGGGGGGGGGGGGGTGGATGGGGGGGGGGGGGTGGGGGGGGAGAGGG
+
1++++2+++++++2++223+))+))1))))0*****.(-''-''''((((,(,,,&&&&))&&)&)0&&))+(+28;9;-&0&&&)&)5&)&&)&&&)+(&
@0GS
CACAAATTCGAGCATCACCTTCTCCCCAGCCCTCTTCACAACCTCTCCAAATACACAGACAAACTCCAGAAAGCAAGAATGCTACTCCCACCAAAAGCAT
+
@CCFFDDFHHHHGJJJJIIIJIIJIIJJGIIIIJJJIJJJIJJIIGIIIIJJJJJIIHIIIJHHCHHFHHFFEFEECEEEBCDCCDDDDCBDDDDDCDDD
@0GT
CAAATTCTCACCAGTCCGTCTCCTTCAAAATCCATTCCAATTACACAGCCCTTCCGACCAGCAGATGAAGATCATCGAAATCACTTTGGCCCACGAGACCG
+
=;=<=@+A4?+22=2@3++33<3?AA3=<A*:@*??=A<?*:*0*0?AAAA))/9AAAA/=2>(.).==>>)>;);>;;1(-;(55((5(,(,8:;&&0(&
@0GU
AAGAAAAGCACAAAAGGAAAGAGGAAGTGGAAGAGAATAAAAAAAGCAAAGCCAAGGAACCTCCTCCTAAAAAGACGAAGAAAAATAATAGCAGCAACAGC
+
CCCFFFFFHHHHHJIJJJJJJJJJJJJGGIIIJIJJJJJJJJJJJJIJJJJJJJJHHHHFFFFDEEEEDDDDDDDCDDDDDDDDDDDDEEDDDDDDDDDDB
@0GV
GGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACAC
+
CCCFFFFFFHHHHJJIJJJJJJJJJJJJHHJJJJJJIJJJJJJJJJJIJJJJIJJHIJJJIJJJJJJJHHHHHFFFFFDDEEDDDDDDDDDEEDDDDDDD
@0GW
GGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCAC
+
=11BDDBADF422+<<@<A?C8EF??CGD*??90*09*9BGII=8.BCFF<AEE:=.;B;;@;A;(---->;@>>88?BB@?@B@B@@BABABBB>44>@
@0GX
GTCCTACCCTCTGTCAGTGTCTCCCATGGAGAATAATCACTGCCCAGCGTCCTCCGAGTCCCACCCGAAGCCATCCAGCCCCCGGCAGGAGAGCACACGCG
+
CCCFFFFFHGHHGGIGGGHHHBHIJJJJIJGGIGJJJJJJIJGJIIJHGCHIGEDAGGGHGIGGEH<DDCDBD@CD@CDDDDDBD>BDBBB@BD>ADB5<>
@0GY
CACCTTCTCCCCAGCCCTCTTCACAACCTCTCCAAATACACAGACAAACTCCAGAAAGCAAGAATGCTACTCCCACCAAAAGCATAAAACGACCATCACC
+
C@@FDFFFHHGHHIIIJIJJJIFIHIJGGIGHIJGGGIEIIIDHIGJGJGIJGIJJJEGGIIGIIIEHHHHHFFFFDDDDDDDDCCDDDDBDBDDDDDCD
@0GZ
CCCCAGTACGCCCCGAGGGTCCTGACGCAGGCTTCCAACCCCGTCGTCTGCACGCAGCCCAAATCCCCATCCAGCACCCCAGTGTCCCCACTGCATCATGC
+
@<?BDDBDF1D6@@E@F@FB;?D>9B@?D0602.=.8CCBAHE9B8,;??>>9?B8=??8<00:>(489CC=>CCC?+29024>(::@?CB2::>CC4:>>
@0H0
CTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGC
+
CCCFFFFFHHHHHHHIJJJJGJIJJJJJJJJJJJJJJJJJJJJJJJHIJJJJHHHHHHFFFFFEDDEEDDDDDDDDDDDDDDDDDDCDDCDDDCCDDDDD
@0H1
CTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACT
+
CCCFFFFFHGHGHIJIIJJJJJJJJJJIJJJJJJJJJJJJJJJJJJGIJIIJJJIIJHHHFFFFFEDEEDD>BCDDDDDDDDACDCDDDDDEDDDDDDDDD
@0H2
CAGCACGCCAGTGTCCCCACTGCATCATGCATCTCCAAACTCAACTCATACACCGAAACCTGACCGGGCCTTCCCAGCTCACCTCCCTCCATCGCAGTCC
+
@B@DFF@DHHHHHJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJIJJJJJJJJJHHHHHFDDDDDDDDDDDDDDDDDDDDDDDDCDDDDDD@DD
@0H3
TACCAGATAGCAGCTACCCCATGGACCACAGATTTCGCCGCCAGCTTTCTGAACCCTGTAACTCCTTTCCTCCTTTGCCGACGATGCCAAGGGAAGGACGT
+
@C@BDFFDHBFFDBHIIIEHIHEIGEEEHGIGHGIGGBFDGGIIIGHIHGIGGHGFHHHHHBEDFFDCEECEECACDCABBD?BBBBDDDDDDDDDD@BDB
@0H4
TGGAGATGTTCTTACTGGAGACTCAGGTGGAGTCATGCTTATATGGAGCAAAACTACTGTAGAGCCCACACCTGGGAAAGGACCTAAAGGGGTATATCAA
+
@@@7BDDB:DFFDG>EG@H@AFH<FADEEAB??CGD??D@FGGGBF9B9BFHFBBG:FFBCBBA@=165@55=AHHEEEDCCA==AC>;A(888@CCCC>
@0H5
ACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGC
+
@@<BDD=:<AF<CCF<CBCCEBG>;?<<C99F9E8DD;D@F@GB;B39BDFC9=FEFFFF:7@EEEE7=;CACDD@B?@@AC:;?@>A>(5;3(:ABBBBB
@0H6
CCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTAT
+
?@@A;DDDFHAHH@EHGGIIH?CHICA3<FG1C3CDGIIGFEH7FFGG9DH8CG4BCCCAAACGGHC;?E=C>?C=CC>@C@,-;(55;?CBB2<&0<><@
@0H7
CCAGTCACGGGAGCCCTCCCTGAAGAATTCCAACCCCGACGAGATTGAAATCGACTTTGAGACCCTGAAGCCGTCCACACTGCGTGAGCTGGAGCGCTATG
+
CCCFFFFFHHHHGFIJJJJIJJIJJJJIIJGIJJJJJJGIJIIJHHHHHHFFFFDDDEDDDDDDDCDDDDDDDDDDDDCDDDDD@DDDDDCDADDDDBDDC
@0H8
CGTCAGAGTGTGGGATTCTGTTACTCTATCCACACTGCAGATTATTGGACTTGGCACTTTTGAGCGTGGAGTAGGATGCCTGGATTTTTCAAAAGCAGATT
+
?@@FFFFFDFFHHJIJJJJJJJIJJJJJJJJJJJJGIJJJGIIIJJIJGIIJJIIJJJJJJJJJGHGIHGHEFEFDEFEEEEDDDDDDDDDDDDDDDDDDD
@0H9
CCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGT
+
CCCFFFFFHHDFHIIIDGGIEGHIIGGHICGGHGHHIIJIIJIJGIJFJ@CCH=?EEECFFF?DEACEEDDBB;>CCCCAD@@?BDCDDDBDDCDCCDBD>
@0HA
CGTCCTATGTACCAACGCCAGATGTCTGAGCCAAACATCCCCTTCCCACCACAAGGCTTTAAGCAGGAGTACCACGACCCAGTGTATGAACACAACACCAT
+
@@<DBDDDFHHGGIGHIGGGGGHHEDGEEIBAHGBFGGE;DHGIGIEDGGECHGGGCHIIJA?CHEBBBCC6>CCBBBDDBBDCABDDDEDCCA?BDDDDC
@0HB
AGATATGTGTACAAGTTTGTGTGTGATCCAGAAGCCCTTTTATCAATAGCCTTTCCTGTTATTCTGCGTTCAAGGCTGAAGGCAGGCATGGAGCGTCATTT
+
;9;3-).@))))8)2.9:):)=7>7)<8<;):4))(())))))209.)0:).=?<))))0))/316);'(-))).687.)8)((6'3((,39(53;6'3(6
@0HC
CTTCTCACCAGGGCCTTGGAAGCACTTTGCCTAGAAGGGGAACCAGGAATGCCATAGTTCCGAGAGAAACTTCTGTTAGTAAAACACACAGGTCAGCAGAC
+
@@@DD?DB?BDDFACAEECG<CGIIC<?99CG4??9CFAD:?GGAG?=BGB@CDCCAC@=>@:',9BCCC@:>>A;C;3>>@>>C<ABB@<?:@A?C:+3<
@0HD
GAACAACTCCGGGCAGAGCTGGATGAGATGTATGGGCAGCAGATAGTGCAAATGAAACAAGAATTAATAAGACAACACATGGCACAGATGGAGGAAATGA
+
CCCFFFFFHHHHHJJJJJJJJJGHJHHGGIHIJJJJJJJJJJJJJJCFHIIJJJIJJJJJJIHHHHGHFFFFFFEDDDDCDDBDDDDCDDDDDDBDDDDD
@0HE
CGCCGCCTCTCCCCGGCTGAAAGAGCTCAGGGACCCAGGCCGCACCAGGAGAACAACCACCAGGAGTCCTACCCTCTGTCAGTGTCTCCCATGGAGAATA
+
@@@FFFDDFHHHGIEAGEDA*:DBDFGIIB>EFDHIIIIIGIBBBFFDB?AAACCCB@?BB9A@D??AC@CDDDDDD>AC:C@>CCCCAACDCCC?CDCD
@0HF
CTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTT
+
CCCFFFFFHHHHGJJJJJJJJJJJJIIJJJJJJJJIJJIJIGIIIJJIJIJJJJJJJJJHIHHHEHHFFFFFFDDDDDDDDDDDDDDDDDDDDEDDD9<9B
@0HG
ACTCTGTCGGCCCGCTGAATGAAGTGCCCGCCCCTCTAAGCCCGGAGCCCGGCGCTTTCCCCGCAAGATGGACGGTTTCGCCGGCAGTCTCGATGATAGT
+
(0;>(6=8(8(--(-88?><88:=:8?16===??9?>8881;;33-9;;;;'3;-:6::6:<:5908+22:7:05595:8::8:95:83:<<<=4<:<<(
@0HH
CTCAAGTAAGCTCTTTATTAGATGGAGTTGTGACTATGACAAGCAGGGGTGCTGAAGGATCAGTTTCTAAAGTAAATAAAAGTTTTGGTGAAGAATCAAA
+
CCCFFFFFHHHHHJJJJJJJJHIJJJJJJJHJIJJJJJJJJJJJJJJIJFHIJJJJIJIJJJJJJJJJHHHHCHHFFFFFFEEEEEEDADDDDDDDCDDD
@0HI
CTCCTGTTTGCGGAAGAAAAGGAAACCTCAAGCTGAGAAAGTTGATGTGATTGCCGGCTCCTCCAAGATGAAGGGCTTCTCGTCCTCAGAGTCGGAGAGCT
+
@?@DBADDFHBDF6FFIEIHIAGIIH;@D@FC>DF3BFHC@*B?DHHDHGBGGCH:BHEHEEEEDCC>>CCC@CBBBBC:><8<?7ACA@ACC>BBB088(
@0HJ
CAAGTTTGTGTGTGATCCAGAAGCCCTTTTCTCCATGGCCTTTCCAGATAATCAGCGTCCACTGCTGAAGACAGACATGGAACGTCACATCAACGAGGAGG
+
@@@DBDDDDDB??DEEDBHGE?GFGGGIIIGGFH@??GGGGHIGGGIDBFEGHBDBFBG@@==@HG@@@@==ACADD@BBCC@>==?BCCCCAABBBB9@>
@0HK
GTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTAT
+
=11:+AADBDDDD:8E<8?;C?3:?D9?B0?0*:B9?D?B=DD@;B.-==C@4746==?AA?;@;6;(.(65>>(;5((,:A8<5<>??3>:+(++>A::(
@0HL
CTCAGAGTTATGATCAGAATCCTTCCCCTAGAGCAGCTGGGGAGAGGGACGATGTCTGTCTCAGCCCAGGAGTTTGGCTGAGCAGTGAGATG
+
?@CDDDDDFHDHHGIGIIIJJJIHEFIJIJGFFHGEIIGEHG??FGIGBFGBEHCGGEEHCEEH>@DBAD;AC?ACBA@BBDDCC:@CD@AC
@0HM
CGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCT
+
@@@DDDDBBFDHHIIIIBHIIHH<<FBABG>:CFGGIII@D>GDDDGGDD9D@;FFCHEHIIG9CDECHECCDDBECCBBB?CCCCCCCCCCCC:<?CBBC
@0HN
AGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACT
+
??1BDBB+ADDDDDED@@FEDEDFF;FBFEED>ECDIIIII:DD;BDEEAEADCCDCD=AC<CDC?C77.?)??A;@A?;;;>AA?59??9=?<3<8<?<>
@0HO
CTTAAGAACACCATGGAGACCATAGACTGGAAGGTCTTTGAGAGCTGGATGCACCATTGGCTCCTGTTTGAAATGAGCAGGCACTCCTTGGAGCAAAAGCC
+
??@DBDDD?FBDHIIC<:CG=F<<<4ACD;GEFD1*C<<FH?:DBGB9?B9?D4=888;>FCFA;@@DE>>?;ABC;;>>?>A==>CCCCC><CB?:?:8(
@0HP
CAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTTATGGGCAGG
+
CCCFFFFFGGHFFJJFHGIJJGIJJGIJIIIGHIJJGIIJJJJJIIIJJIJIEHHEGIJJJIGHADEDEDDBDDBD<B@CCCDEDDD9<BBDDDDDBDCDD
@0HQ
AAGAAGCTGAATTAGAGAGGCTGAGAACACAGCTTCTATTTAGTCACGAAGAAGAGCTTTCCAAACTGAAGGAAGATTTAGAAATTGAACATCGAATAAAT
+
(7((<;)99)6)29>))28<(8>(:)))87.;?8;=?==??=<71=13(3=(.:>;??>????>83139:9>7)(6)6(.(6(6:4(6;<7(8502;;=<=
@0HR
GTTTCTTTTGAAAATATGACTGTTGGAGAAGAAAGTAAGCAAGAACAGTTGATTTTGGATCACTTACCATCTGTAACAAAGGAATCATCACTTAGAGCAAC
+
@?@FDDFFGFHHFI@CEHGCHHHIIIIIIEGEIGIHGGIIIIGGIIICGHE>ECEIGIIGIIIIIIGGIIIIIIGG?EEFHBDFC?CCACECEDDAACCCA
@0HS
AAAGCCTTGGCCCGGAGGCACCTATCCCAGAGTCCTGACACAGAAGCTCTTTCCTGTTTTCTTATCCCAGTGCTTCGTTCCCTGGCCCGGCTGAAGCCCAC
+
@@@FDFFFDBHHGIGIIIIAHEHHIEGGHGGGIGIIIIGGHHIIGIIEHIGGCEHIIFHHGH<CCDFBD>>CEEECBACBDDCA@@AB9<B>D?C:@ABBB
@0HT
GGCTCAACCACAGGTTTGTGTGCTACCCCCCCTGCCTCATTACCTGGCTCACTAACCAACGGGAACGCCTTACAGAAATCTCCAGGCCCTCAGCGAGGA
+
;((28@)8(;(.=7)22(()3<186=?8@???3<????)6>3:>3).<)..).;6.9=3/=/;'9('',(,(82(((((+++:(86((((2+(+8&5&&
@0HU
GGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJHHFFDDEEDDDDDDDDDDDDDDDDDDDDDDDDEDDDDD
@0HV
ACCTCCTCCTAAAAAGACGAAGAAAAATAATAGCAGCAACAGCAATGTGAGCAAGAAGGAGCCAGCGCCCATGAAGAGCAAGCCCCCTCCCACGTATGAGT
+
?=@BD?BDFDHDDB?@FHEEFGFABGB??GD?:??FHDB???BDHGFIE@HDDC;FCHID@=5A=C<DA3;>;>ACCCCC?<9@<95<<?898>B9AC@C4
@0HW
AAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTAC
+
@CCFFFFDHFHHHJIJJJIIJIJIGIIIIIIIJGIJJJIJJJIJJ@FHGIIJJGFFHFFFFDEEEDDADDDDDDDDDDCCDDDDDDDDCDDDDDDDDD>CC
@0HX
TACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCT
+
@@@FFFFFHHGHHJIJJJJIIJIDGJIJIIIIJJJJJJJJJJJIJJJJJJJHHHGDFFFEEEDACDDDCECCDDDDDDDDDDDBBDDDEDBDDDDBDDCCD
@0HY
GAGCTTGTATGTGAAGTGGGGTCCTCGGATAGTTTAAGTGAGTAGTGGTACCTCCTTCAACGCCTGGAAACCGTTGGACTGTGTGGTGGGGATGCTGTGGG
+
+++22+++,2,,2,2+,2?+3))22+:8)))****0**0*****0**(0/9)))()/).))-''.(.()))(',(((-(((((,((,((&&(&((+((((&
@0HZ
GGAGAAGCGGCAGCTCAGCTTGGACATCAACAAGCTCCCCGGCGAGAAGCTGGGCCGCGTGGTGCACATCATCCAGTCACGGGAGCCCTCCCTGAAGAATT
+
C@CFDDDFDHHHHJJJGIIJIJGGHHJJJJJJJJIIIIIIIGIHFDDDDDDDDDDDDDDBDD?BCACDDCDDDDDDDDCCDDDDDBDDDDDDDDDCCCDDD
@0I0
TCTAGAAATCCGCTTGTGAGTTAAACTGTTAGTGCAAAGCGGATCAGTTGTTTGGAGAACAGGAAAAAGCAATGTAAAAAGAGGAAAAGATTTAATACAA
+
((0((..)9>)0-@33;4=).4)):).)@3<>)18))..)(0<((0))/)/..=1..=6).<3:7)6='(((.((.((((',3(,;7;(,(5:2((+((+
@0I1
CTGATGGACAGCAGATACTTGTGCCCAGCAATCAGGTGGTCGTACAAACTGCATCAGGAGATATGCAAACATATCAGATCCGAACTACACCTTCAGCTACT
+
?7=D=;DDBDAFBBBGB@<C@HEECFC8CAC9?FDD:?D:?DG;GAFG@F?FCBFE>@CH;=@G777.3=?EBDC>?7?AA=A?BB>>@?:3::AC@>AAC
@0I2
AATGAGCTGTGTTCTCAGAAGGTCTTTGTCTCCAAGGTGGAGGCTGTCATTCACCCTCAATTTCTGGCAGATCTGCTGTCCCCAGAAAAACAGAGAGATCC
+
@@@FFDFFGHFHHIIGIIHIJECBCHHG?EDFHIIJJ<<F@CDEGHGHHIGFGIHCGBFIJJGIGIIEEHCEC;CEEE@DFFDCDDDECBBACCDCB?C@C
@0I3
CTCCTACCGTCTTCGTAGCGTACTTACAAACATCGAGCTTTAATAAAGCCTGTTTGTAGCTGTGTTCCTCAAAACCCCCAATAACCGCAGAAAATTGTCGT
+
(-(23))2(2(@(;(.)(((-((())2:;:(())()00;96)))).)))(..8=:)61:).))))).).9.)...(,'332((((,,'0&&((++2(3(0+
@0I4
CGAAGAACTTCAGAAGAGAAATCATAAAGACAGCCAGTTCGAAACTGATATAGTACAACGAATGGAACAAGAAACACAAAGAAAGTTAGAACAACTCCGGG
+
@@@FDDDDF<FDB9?ADBEFGHIGGEHIBGHEA??F3C?FHID;@<@B4B?F*?<9==BAGHCFA;D;C;ACEB;;;=AA>CB?;;(;;>>>AC9::CB99
@0I5
CCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGT
+
CCCFFFFFHHHGHJJJJJJIEHIJJJJJJJJJJJJJJJJJJJIIJJJJGIJJGCACEHFFFEFFEEEEEDDDD>ACDDDDDBBDDDDDDDDDDDDDCDDDC
@0I6
GAAAGATTGATTTTCTTAGACTCCATTAAGTCCAAATCCAAAGACTCTGTGTGGGAAAAAGAAATAGAAATACTTATAGAGGAAAATGAGGACCTCAAAC
+
C@CFFFFFHGHHHJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJGIHHIJIJJJJJJJJJJJIJJJJJJJHHHHHHFFFFFEEEEEEDDDDDDDD
@0I7
CACAGACAAACTCCAGAAAGCAAGAATGCTACTCCCACCAAAAGCATAAAACGACCATCACCAGCTGAAAAGTCACATAATTCTTGGGAAAATTCAGATG
+
@@@=DDEDHDDDHIEHEIIGCFBGEHEHCEEEHIIEEIIIIIFIFIGGIGEHBEHIGIIIDHHDFFEFFFFD>AEEECDDCDADDDDDBDDDCDDCD@CC
@0I8
GAAAGGGGGGAAAGAAAAAGGGAGCAGAGGAAGAGGATGAGGAACTGGCCAACTTGGCTGACCGCTGGGCCTCTAAACTTGGCCTCGCAGCAAGGGAGG
+
0(--(@(<(',)8;878;77827:728(+82+22262(++:2(+8:((26668/5(52(((++)&))09596((++(((((+(+(()&)&087<<<8:0
@0I9
CCGAGTTGCAATCAACTGTGAAAAACTTACTGAAACATTAGTTAAGCAGAGTGTCATAGTGGCCTATGAAGATTGCCACTTCAACTTGCACTGTTGCCAA
+
===7?2++<2<,2<2<,+3<?AB<+)+2A@7@=4??A>B1*:*0**7*)05*979*//9?/==..>9>9AA).77>AAA9))...).;3>;>>>@((-(5
@0IA
CCCGCCCTCGCCCGAGCCAGCCCTCCTCCCTGGCCATGCTGGACCTTCTGCACGTGGCTCGGGACATTGCCTGTGGCTGTAAGTATTTGGAGGAAAACCAC
+
?<<DB188DD18)@EEE<;CBDDD@BDCEDIIC<;=@@8@DC(@@C;77==;7?;?@@2-;??;8(4:3>:AA(49(2<24+4:>BBB>>(3<229938<8
@0IB
CAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGC
+
@@??DDDFHDFBFGHGHIGGHBHIECCGHGIGICHHGHGBGFHGIE><?9BGGH@>8=FGHIE@;(=@;=?EHFFFFF@CA;>;>CB?C@B<<8>@054@C
@0IC
CTTAGCCGTTCACTCCGCTATTACTATGAGAAAGGAATTATGCAAAAGGTGGCTGGAGAGAGATATGTCTACAAGTTTGTGTGTGATCCAGAAGCCCTTTT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJ?FHIJJJJJIIJJHGHGEHFFFFFFEEEEEACCBBBCEEDDDDDDDDDDDDD
@0ID
CACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGC
+
@@CFDFFFGHHHGJJJJIJJJIJJJGJJJJJJIJIIJJJGIHJJJIJJIHIJJJJIJJIIGHIIHHHHEHFFFDFDEEDDDDDDDCCDDDCDDDCCCDB
@0IE
GTGAAATGCCTGGAAAACCGAGTTGCAGTCCTGGAAAATCAAAATAAAACTCTAATAGAAGAGTTAAAAACTTTGAAGGATCTTTATTCCAATAAAAGTGT
+
CCCFFFFFHHHHGJJJIJJJIJGIIIJJJIJJJIJJJJJJJJJJJJJJJHIIIIJJJJJJGGIIHJJJJJHHHHGFFFFFFEEEEDEDDEEDDDDDDDCDD
@0IF
CCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJIJJHHHHFFF9AEEDDEDDDDDDDDDDDDDDDDDD
@0IG
GGCAGTTTTATGATGACACCTGTGTTGTCCCAGAAAAATTCGATGGAGACATCAAACAAGAGCCAGGAATGTATCGGGAAGGACCCACATACCAACGGCG
+
CCCFFFFFHHHHHJJJIJJJJJIIJJJJJJJJJJJJJIJJIIJJJJJJIJJJJJJJIJJJIJIJJJIGJHHEHEHFFDDDDDDDDDDDDDDDDDDDDDDD
@0IH
GGACTGTAGAGCTAATGTTTACCTTCTTCCGACCGGGGAAATAGTTTATTTCATTGCATCAGTAGTAGTACTATTTAATTATGAGGAGAGAACTCAGCGAC
+
?@??DDDDF<FFF@AEHBFIECH>BEHDAF@@?1DAHI<AH9@C=CG@DG4=@AEA?7AEDC>@C?@CDDCCCAC@CCADC@C<CA:??BBC>C>A@A>.0
@0II
ACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCT
+
@@CFDEFFHHHHGJJJJJJIJJJIIJJIIJJIJIEDFHGJJJJIGHIIJJJJHHHHHHFFFFFFEDDECCCCDCCDCDCDDDDDDDDD:ACDDDDDDDBD
@0IJ
GGATGGCACCAGAAGTCATCAGAATGCAAGATAAAAATCCATACAGCTTTCAGTCAGATGTATATGCATTTGGAATTGTTCTGTATGAATTGATGACTGG
+
@C@FDFFDDFFHGIH@EA<D<ECEFEHIIEFCFHEEGIBBE<BGCCFFCHIIIEDD@BFH=CHHG@G@AFCDGGICEG@A?ACAAC;@;C@CCCCCEC@?
@0IK
AAAAAAGTAGAAAACTCAAATAAAGAAGAAATACAGGAAAAGGAGACAATCATTGAAGAATTAAACACAAAAATAATAGAAGAAGAAAAGAAAACTCTTG
+
?@?BBD@<CFHDH?AA:<FHHEBHIIGIGDEDF?CFGIABGFC@?27DDHBGHIA=FFEF=@CHE@D6=AHEEEED@;>@A6?;>>C?C5?9<C?:C@@C
@0IL
GTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGC
+
CCCFFFFFHHHFHIIBGHIIDIIIJFGHJGIIIJIGIJGCGIGGIIIAGEHGHHHHHFCCDFFEEEEFEDDDDDDDDB>CCDDDDDDBDDDCDDDDCDD
@0IM
ATGGAAAAAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCC
+
C@BFFFFFHHHGHJJJGJGIJIIJJJJJJJJIJJJJJJJJJJIJJJJIIHFHHGFDDFCDDDDDDDDDDDDDDDDDDDDDDDAACDEDDDDEDDEDDDD
@0IN
CAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTTATGGGCAGG
+
@<?DDD?;A:CFD:2AG?,A:CDBFFD9F8:9:BE?B?)0?0*?@F6DE1CF9@7@C=@D4)@=EDD;;6=@BB>'5<((:3:(:?<309<3:(+:8(9&0
@0IO
CTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGTATCCT
+
=???B;DBBDCAD1)<<+ACB?<?E<??3?D?B*:DD??BBDDBDDDCDBEDECDE@E:;;ACADD2??>;;5;??A;>D>:AAA==??<<>>AA(44+::
@0IP
CCCAGGCCATCCGTGGATAATGTGCACCATAACCCTCCCACCATTGAACTGTTGCACCGCTCCAGGTCACCTATCACGACAAATCACCGGCCTTCTCCTG
+
CCCFFFFFHHHHHIJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJIJJJJIIJIJJJJIJIHHHFFFFEEEEEEEDDDCDDDDDDDDDDDDDDDDDDDDD
@0IQ
GGTAACCTGGGGCTGGAGGGAAGCTGTACTGTCCCACCTAACGTTGCAACTGGGAGACTTCCGGGGGCCTCACTGCTCCTAGAGCCCTCTTCGCTGACTGC
+
@@?DDDDFHHGGGBHJEHIIJIJIIJDGGGIIJIGGIIIII@DHGGIGGGGIIJGIEFEHDFFFDDDDBDDDDDCDCCDDDCDDAABCDDCDA>BDDDCCC
@0IR
CCCGTCCCCCGTGCCCCAGTACGCCCCGAGGGTCCTGACGCAGGCTTCCAACCCCGTCGTCTGCACGCAGCCCAAATCCCCATCCAGCACGCCAGTGTCCC
+
B@BDDFFFHHHFHJJJJJJFHGIJJJIJJJJJGGIJJJIHHFFDDDEDDDDDDDDDDDB@DBDDDDBDDDDDDDDDCDDDDDDCDCCDDD9>BDDDDEEDD
@0IS
GGGAGACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGCCCACGGATTACAGTACCTATAGCCAAGCCGCAGCGCAGCAGGGCTACAGTGCTT
+
@@<DD?=A?FDF@CCC@?FBEGEGGBHCFBDB?F@26CHG@=736AHE9<CCBB>;ACC>D>CA;A:5;@@@??B@<<B559-9008<85<28?:>+4:@>
@0IT
CTGAGTACAAGCTGAGCAAGCTCCGCACCTCGACCATCATGACCGACTACAACCCCAACTACTGCTTTGCTGGCAAGACCTCCTCCATCAGTGACCTGA
+
C@@FFEFFHHGHHJIJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJHHHHHFFFDDEEDDDDDDDDDDDCDDDDDDDDDDCDDDDDDDDDDDDDDD
@0IU
GCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTAT
+
@@@FFFFFHHHHHJJJJJJJJJJJJJJJJJJIIJJJIJIJJJJJJJJIJIJIJIJJJIIHIIJIJHIJJHHGHHHFFFFFEE>CEDDDDDDDDDDDDDDDD
@0IV
TATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTC
+
?;???DDB?DD<D@+<<@3@@@F9:?C?1:::??C;9::DE<?D?9?88?9BC;8BCE@D4)667;==?<@<@==;;>;A3:>?2=?<?A>A>AAAA>A:
@0IW
CAGCAATGTGAGCAAGAAGGAGCCAGCGCCCATGAAGAGCAAGCCCCCTCCCACGTATGAGTCGGAGGAAGAGGACAAGTGCAAGCCTATGTCCTATGAGG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJIJJJJJJJJIJJJJJJJJJJJJJJH=EFEFF@DCD>BDDDD@BDDBDDDCDDDDDDDDDDDDEEDDDDCDD
@0IX
CTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAA
+
CCCFFFFFHHHHHJJJJJHJJIJIJJIJIIJIIIJJIIJJJJJIJJJJJIJJJJJJIIJJIJJHHFFDCDEEDDDDDDDDDDDD>CDDDDDDDCCCDDDD
@0IY
GGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTAC
+
@@@DD?BDHHFFFG@HGEEGIJFJGEEIGIGHGEIIIJIJGIIJIEHGGHGGEEGEHFAEDDDDC63>>ACDCC<AA>ACCDDCCDD@CCC>@ABCCCDCC
@0IZ
CCTTATTCAAACATCAACAACAGGGACCAGGTGCTTTGTCCTCCATGGGAGTATAATAAATGATGTGGCAAGGGCTTACTCTCCATGAGAGGAATGTGTG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJFGIJJJJIJJJJJJJJJJIJHIGJJJJJJIJJJJGIJFJJHHHFFFFFEECEEEDDDDDDDDDDDCEFD
@0J0
CGGGACTCGAGTGATGATTGGGAGATTCCTGATGGGCAGATTACAGTGGGACAAAGAATTGGATCTGGATCATTTGGAACAGTCTACAAGGGAAAGTGGC
+
CCCFFFFDHFHCFHHGGHIJFIJJBEHGIJJHHHGGHIIFHIJJJICGIIJJJIIJJIEEHIJIJHHHGEHFFFFFFEEEEECDDDDDCCDDBDDDCCDD
@0J1
CCGAACTACACCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATGACATCTCCTGTGACTCTCACCTCTCAGACAACTAAGACAGATGACCCCCAATTG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJHHJFGIJIIJJJJJJJJJJJIJJJIJJJJJIJJJHHHHHFFFFFEEEEEEDDDDDDDDDDDD
@0J2
GGGAAGCAGCATGAGATTGAAGAGCTAAACAGAGAGCTGGAAGAAATGAGGGTTACCTATGGGACTGAAGGACTGCAGCAGTTACAAGAATTTGAAGCTGC
+
@@@DDDDDDDAFHIGGAHE@GG>EGHGGH9ECBBEHGEHEEGHGFFCHICGGH@DHGC>>FEGIIIIH>ECED@B@DCCCCCCCCCC@==CCCC>CCCCCC
@0J3
AAACTTTTGTAGCAGAAACATTGGAAATGGGTGAGGTTGTTGAAAAGGATACAACAGAACTCATGGAAAAACTTGAGGTAACCAAGCGAGAGAAATTAG
+
@@@F?DDAFHHHFGIEBHI@@DHBFGGEHEGDFEAHGCGFAGF9DDGIEGFEHIIIIIIC:7888DHEHGGAEHCFE@);;A@>B@BBCB:@@CCCCCC
@0J4
CTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCT
+
@B@FFDFFHHHHHIIIJJJJJJJJJJJJJJJIJGHIJJJJJJHJIJJJJJJJJJJJIJJJIJHHFFFFFEEDDEDDDDDEEDDDDDDDDDDDDDDDDDDDD
@0J5
TTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGC
+
@@@FFFFFGHFHFGIIIJIIGIIJIJJJJJJIJJJIGHIJJJIHGHDHGIJJIJGGJIJJGJIH@HHHFDFFDDE>CEEEDDDACCCBCDDDDDDDBBDA@
@0J6
CCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTAT
+
=;1A:BDA??3A<C<;3:?@1@1):8)?;BDDEEBDDECDDDEEDA@AACDDDDDDDDDAAAAABABD;>?A29(9??=8<8144>A>>8<<8<?833:>>
@0J7
ATCAACAAGCTCCCCGGCGAGAAGCTGGGCCGCGTGGTGCACATCATCCAGTCACGGGAGCCCTCCCTGAAGAATTCCAACCCCGACGAGATTGAAATCG
+
??@DD?BDFBBCCDGIG>G?DFAGABDGGEGEGEHEC?;9>ACCCCA@C@CCACCBBB07@BBCBBB?C9@CC9>>A>CACBBBB55>99><CC@CCC@?
@0J8
CCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACA
+
CCCFFFFFHGHHHJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJHHFFDEEEDDDDDDDDDDDDDCDDDDEDDDCDDDDD
@0J9
GTCGTACAAACTGCATCAGGAGATATGCAAACATATCAGATCCGAACTACACCTTCAGCTACTTCTCTGCCACAAACTGGGGTGATGACATCTCCTGTGAC
+
?1=A:AD?FFDF?EBDHI3:CGG@HGIIDHECHHCEEG9<BDFCH7@FBG@;FFGHG>GHAFC>;D:7@DEEC=BDB>@(;<>89:>@C@CCC@CCCCCEC
@0JA
ATGAAAACACGGCATAAGGGAGAAATGGAGAATGCTTTAAGGTCATATTCAAATATTACAGTTAATGAAGATCAGATAAAGTTAATGAATGTGGCAATAA
+
@@@AADDAFAFAFF>EDGBBDD@FCAFGCG@F4BDGE>@@F<*98*?>D>CCE>DEBFDAHA:@C>DC;D>>;=AC@;@@>7;@@3>>@3;(5;;;@:AC
@0JB
GTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCC
+
@@@D?ADDHDAFFBEGIA;B;FHIIIEGHIGGIIDGGG>FEGIIIEEGGIEFFIGGGIIHHH>E7?CDEECCCC?;=ACB>>CCDCDCACCCCCC?CCCBB
@0JC
GGACACACCATGCTCCCCATTCGCTGGATGCCTCCTGAAAGCATCATGTACCGGAAGTTCACTACAGAGAGTGATGTATGGAGCTTCGGGGTGATCCTCTG
+
;+:;ADDABCD>BBEEDE>EE:<CF@EBADDEADDD@DEDDCEDE>DDBDCEADIID7@AADCD>=>3?A>.6(..(;-;;(,;;>(8;?>;?8:>A:>:4
@0JD
GGAAACTTAGAGGTGGAGAGCAGAGAATTCACTTATCCAACATAAAAATAATGGTCAGATATGAACTGTTCAAGAACTTGCCGTCAAGGATTGTTAGTATT
+
(0-8:.26;<)).).3(:)((.3)(.).66))))1:.)..7?5))))00).3<<))...))/.)8./).)...))).)..)),,'('(-(-((((((((,(
@0JE
CTGGGGAGAGGGACGATGTCTGTCTCAGCCCAGGAGTTTGGCTGAGCAGTGAGTTGGAAGCTGTAGGCTTGGAGCTGCCTGTACAAATAGAGGAGGTCAT
+
881+B?DDA:C::?EE?8:<C<FGG<G49DBBG)0?8BFFFCFF;(.@D7=)=)77))).6;;7;;>6;6',-5((,(5>(,,,;5>:>@A3?(80(((+
@0JF
TATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGACCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCCTCC
+
1??>BDDDADB>?:A@EEB933?D9B<?;2CF?191:*):?BDD6D(<@BDIEIEE@C:@CC>C9...7;A36;..;A>A??(;A?95((5:2<<0<1(3(
@0JG
CTCTGCCACAAACTGTGGTGATGACATCTCCTGTGACTCTCACCTCTCAGACAACTAAGACAGATGACCCCCAATTGAAAAGAGAAATAAGGTTAATGAA
+
@@@A?ABD?F?:C<?,22<?EH@@F9AEAH+:::*:9C>CB1*?F33D@BF3B?F><B=.8=;FA)).)(;8:(77?>D((65.;(5>@@@>:,(,,53(
@0JH
AAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACC
+
@@@FFDFFHHGHHIJGIGIJJIIGJJJIJJIIIJIGGIIJJIGHIJAHIIIHHHFFFFFFEEDEDEEDDDDDDDDDDDDBDCCDDDCCCDDEDDCCBDDDD
@0JI
GCAAAAGGTGGCTGGAGAGAGATATGTCTACAAGTTTGTGTGTGATCCAGAAGCCCTTTTCTCCATGGCCTTTCCAGATAATCAGCGTCCACTGCTGA
+
CCCFFFFFFHHHGIJIJIJGIIIJJJIJJJJICHFGIIIIFHFHIJIJJJJJJJJJJJJJJGIJJJIJJHHHGHFFFFFFFCEEEEDBDD@DDDDDDD
@0JJ
GACTCTGAATGTGAGCATCTTGGTGAGACGAGGAAAAGAAACGGGACAAGATTCCCCAAATAAAAACGGGGGAAGAAGGGAGAGCCCAGGGCCAAATGCTC
+
0((((.)<1=)8)=)@)8))8.)3()(.)<(15((.7)3(6)7(((-((.83):8)))(())8)))',(,,8-:-9(8:-8&0(+(2((+)+2(+8;(4(+
@0JK
GATGGAAGGCCTCTACAACCCCACGTCAGAGTGTGGGATTCTGTTACTCTATCCACACTGCAGATTATTGGACTTGGCACTTTTGAGCGTGGAGTAGGATG
+
;=77+++++<=A@ACBCACA<8<AABB7A<?1?00?=<BA*?/?A7?AAA>AABBBBAA;7).>>AAAAA));>>@@>>;>=?>;;;92=6=(289???;8
@0JL
CCGGCAAAGCCAAGCTTGCCCAGTTTCGACAAAGAAAAGCTCAGTCGGATGGGCAGAGTCCTTCCAAGAAGCAAAAAAAAAAGAGAAAAACGTCAAGCAGT
+
CCCFFFFFHGHHGJJJIIIGIIIGIIIIIIIJJGIIJJIIEHIIIJJJJIFGJEHEFEDDFFFEEEECCDDCDDDDDBBDD3-2(9>CCB30+289>:83+
@0JM
TTTTCTTAGACTCCATTAAGTCCAAATCCAAAGACTCTGTGTGGGAAAAAGAAATAGAAATACTTATAGAGGAAAATGAGGACCTCAAACAACAATGTATT
+
CCCFFFFFHHHHHJJJIJJJHIJIIGIJGEHIGIIGJEHDF?DHGIIJJIIJJIIIJJJIIJJIJIGIGIJJJIHGHGHFFFFFDEEEECDDBDDDC:B>C
@0JN
CCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCC
+
@@@DDBBDAHDD<EFAFCHBDDE;FHGGGGEIEIIIGIIIDIEGI>FBFGHGIGHGGIIGG=FE;@GGEHHFHB>?@>3;>@@>CBB;>?<B?B??B?BBB
@0JO
CCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCT
+
@CCFFFFFHHHGHJJJJJJJJJJJJIJHHIIJJIJJGIJJJJJJJJJIJJJIJJJHIJJJJJJJJJHGGHGEFFEFEEEDEEDDDDDDDDDDDDDDDDDD
@0JP
CTTCTCCTGACCCCGAGCAGCGGCCCCTCCGGTCCCCCCTGGACAACATGATCCGCCGCCTCTCCCCGGCTGAGAGAGCTCAGGGACCCAGGCCGCACC
+
CCCFFFFFGHHHHJIIIJJIJJJIJJJJJIJJIGGIJJFFCDECEDDDDDDDDDBDBDDDBDCDDDDDDDB@BD>C?BDCCDDDDDDDDBDDDDBDDDD
@0JQ
CAGACAATAGCTGAACAAGAAAGTAAACTTAATGAAGCACATAAGTCCCTTAGTACAGTGGAAGATTTGAAAGCTGAGATTGTTTCTGCATCTGAATCC
+
CCCFFFFFHHHHHJJJJJJJJJJHHIJIJJJJJJJJIJJIJJJJIJJJJJJJJGIHIIGHIJJIIJJIJJJIJJJIIJHHHHHHFFFFFFEEEEEEEDD
@0JR
CAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCT
+
CCCFFFFFHHHHGGHIJIJJIJGGIIJIIIIFIJJGHGIJJIJJJJGGIGIGJGGIJJIIJJHHGHBFFFEEEEACCDEDDEDDDDDD<ACCDCCDDDD9
@0JS
TGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACAC
+
?@<DDFDFHCDHHIIIIGGHECCHHIICAFHHIIGIIIGGEHGIIIIIIIIGGIIIBFGGIGGIEGEHFGHGHFFFFFEDDCDDDDCDDCCCDDCCCDCA9
@0JT
TAAATATTGAAAAACTTAAAGATAATTTAGGCATTCACTATAAACAGCAGATAGATGGTTTACAGAATGAAATGAGTCAAAAGATAGAAACCATGCAGTTT
+
CCCFFFFFHHHHHIJJJJJJJJJJJJJJJJJJJJIJIJIJJJJJJJJJJIJJJJIJJJJJJJIJJJJJIJIJJIIJHJIJHHHGHFFFFFFEDEEEDDCDE
@0JU
GTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGC
+
?@<DBDDDFFHHHI;?EGDBFEFHEFBCCHHIIIAGE<BFHII@GGHAFGGG=@AGIIIEHGFHFEB@2;@>@>C@@CCCDD;>5:>A?8?A?99:?BB8B
@0JV
GTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGAT
+
@<@ADDDDAFFFFFA<AEFGCFGDC@D>3?@?DFEF9DBB?BDFF9DBFFF<B<B@>F3@D@=57???7?;@@@B>DCAAAAB@;@??B8;?0>:>@>A:+
@0JW
AGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCAC
+
CCCFFFFFHHHHHJJJIJJJJJJJJJJJJJJJJJJJJJHIJJJIJJJJJJJJJJHHFFFDDEEEDDDDDEDDDDDDDDDDDDDDDDDDDDDDDDDDDDDED
@0JX
AGAAAAGTGCCTGTACAATGTCAGTGCCTATGATCAGAAGCCACAAGAGGGAATGAGGCCCTCCAACCCCCCCACACCATCCAGCACGCCAGTGTCCCCAC
+
?<?DDDD=?DDDDBEEDEEEF@:CFBEEDCE<EFIIIEEEID@DDID)?;@6?BDDDDCCIIIDCEEDDDD@?:;8=??AA>::>>????>>AA4:AA><9
@0JY
CTGCTATAAGTACAACCCTCCTGACCATGAGGTGGTGGCCATGGCCCGCAAGCTCCAGGATGTGTTCGAAATGCGCTTTGCCAAGATGCCGGACGAGCCTG
+
@@@DFDEDDDCDFHGIIGIGIGGDHIHBHFE>:;?:?B?FHG@BFEDGBGGGI@@@@???ADF@?CB?BED=3>;?BDB>CCAC@BCCAC<B>99<5>@AB
@0JZ
TATGTCTACAAGTTTGTGTGTGATCCAGAAGCCCTTTTCTCCATGGCCTTTCCAGATAATCAGCGTCCACTGCTGAAGACAGACATGGAACGTCACATCA
+
@@CFFFFFHHHGHJIJIIHEEEHIIJJJJCGIJJIJJJIIIIGIEHIGIJIJIJJJHJJIJGHHHJGIIIIIHGHHHFFFFFECEEEDDDDDDDDDDDDD
@0K0
CACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGC
+
@<@DFDDDDHFHDEGGIJJJGIIGIIEGGJGHIIHGIJIICGEHIIIGIEGHIJIJJEICDGHIGFFBD@ACDCDCCDDDECBDBDB?ABB?BDD?B@@CC
@0K1
AGGCATTTGCAGCTCCAGACTCAATTAGAACAGCTCCAAGAAGAACCCTTCAACTTCGAAGCAGCAAAAGATGATAACCAAATACGTTGTAAAGGGTT
+
?@@DD;DD<CAFHBHBHGICAFGBFHDHHGIIDIIFCEHGBCGBF)))0*)0**/*)(.(('))..=C?)(.)).).)((6(((-(5(((,,5(((5(
@0K2
CATCAACAAGCTCCCCGGCGAGAAGCTGGGCCGCGTGGTGCACATCATCCAGTCACGGGAGCCCTCCCTGAAGAATTCCAACCCCGACGAGATTGAAATCG
+
@@@?DDDDDA?CA:<?EEEHAFGAF>BB;FH9FBEB9A6?CCA>AACCC>>A5,:ABBB;@38@CBBBCC?@CCC@CCCACC@<<><059>5?CCCCCCCB
@0K3
AAAAAGAAAAGAGATGAGAGACCACTCTTTCCCCAAATTCTCGCCTCTATTGAGCTGCTGGCCCGCTCATTGCCAAAAATTCACCGCAGTGCATCAGAACC
+
CCCFFFFFHHHGHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJHHFFDDEEDDDDDDDDDDDDDDDCDDBCDDEDDDDDDD
@0K4
TGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTAC
+
?@<DDDDFHHHAHGIIDGHEHHHGIIIDGGDGEHIBHCGFGIIIGAFGIIAFGICGGGIGHHHDBDDFFDEBAECDDDDDCC8=62<@D<CAC>@CDDDC
@0K5
TACCAAAACTGCAGACAAGCATAAAGATGTCATCATCAACCAAGAAGGAGAATATATTAAAATGTTTATGCGCGGTCGGCCAATTACCATGTTCATTCCTT
+
@<@DDFFFDFFHHGFGDHGGICHIIGG<F@FHHCHIIIIGGDHGHIIDIIIIIIGBCEGGDHII@FHGIGCHAEF=C@BBDDDCCCDDDDDDECCDDDDDD
@0K6
GCCGACGATGCCAAGGGAAGGACGTCCTATGTACCAACGCCAGATGTCTGAGCCAAACATCCCCTTCCCACCACAAGGCTTTAAGCAGGAGTACCACGACC
+
@@CFDFFFHHHHHJJJGIIIJGIGGIIJGIIBGIII>F?GBGIHE@EDEHHGHFFFFFACEEDDDBDCCCDBABDDDDDDDDDDCCDDB@DDCDCDDDDDB
@0K7
TATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGG
+
@@@D1BDDF=FFFEFFF?GEDDF>B<@DFFGCFEFFGGFFEIFAFBEEAEFFFDBBD@CC>A>>;A5>5???B??8??8?B:@BBA?B@@BBBBBBB@@:4
@0K8
CAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCT
+
@@@BDDFFHDFHHFJIJJJGIGHIII?FDDHIEHIGIJJJGGGGHIIDGHEHEEBDEFB@C@>@A@CDDD@?@BB@ACDDDDDBDBBBDDDCCCCDDDD?
@0K9
ACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGT
+
@CCFFDDDHFFHHEDHHGCEHHGF@FFFEFDEHGIGIBFBFHIIHGHGIGIJGJJCHGGIGHICDHH>EHEDEBDEAAEEEEECACCDCCDABDB?@BBCC
@0KA
GGCCTCTACAACCCCACGTCAGAGTGTGGGATTCTGTTACTCTATCCACACTGCAGATTATTGGACTTGGCACTTTTGAGCGTGGAGTAGGATGCCTGGAT
+
?@<BD;:DCB<FD:FFFEA<<C<9:?9??<9:B>G<:?B<BGF94?B8DFAAF=B;=FC@D@DF>CCEEDF7;37).655;3398(9(,::35>?BB@BB>
@0KB
CCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGT
+
@@@BDDDDFFFDDHGI>CFHBHIEHIEE@CBG?CFH<FFGHABF<FHEG@F=CBF38CGAH>GHHF<B89?A?=;-;;A@;>;>88;<<AA?AABBBBBC
@0KC
GGAGAAGCGGCAGCTCAGCTTGGACATCAACAAGCTCCCCGGCGAGAAGCTGGGCCGCGTGGTGCACATCATCCAGTCACGGGAGCCCTCCCTGAAGAATT
+
@@@DDDDD:DHFHEGHIGCGGHGGFGHHIGDHFHIBDGGHHIGHFBDD?>;@CB?9?BB5;B(8>:::CDCC>ADD@ACDBB@B9>B?AABBCCCCCDC@C
@0KD
GGACTGGCAGAAGAAAGCAAAAGGAGCAGAAATAAAGACAACAAATGAAGTTGTTTTGGCTGTGGAGTTTCACCCAACAGATGCAAATACCATAATTACAT
+
CC@FDFDDFHHDHGIIGBHIIDHGFHGGGCHIGHGIIIGIICH@FGGIJIJHABGGHGJEGH@GHACEED@@@DF?AA?=ACDDDDDADCDCCDDCDEACE
@0KE
AACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGG
+
?@@DDDDDFHHHDGHIBG6@@?F9EDD@GHGDDG>GHIHGAFH@HIICFDHGICGHGGGIBEEHHFEEEECC>ACCBB??BC@;@ACCCCBBBBBB@?:@?
@0KF
TGTCGCAGAAAGAAGAAAGAATATGTGAAATGCCTGGAAAACCGAGTTGCAGTCCTGGAAAATCAAAATAAAACTCTAATAGAAGAGTTAAAAACTTTGA
+
@@@D?BDDFD?DHEEHEBG?BEEEEA?FFEFHGEEDD@BFBHIBDD?CDBGIBA@C@FA@DCDCEHEE>BCEC>;>@>ADC@@C;A=;>CDACC:@CCCA
@0KG
CTGTGGAGTTTCACCCAACAGATGCAAATACCATAATTACATGCGGTAAATCTCATATTTTCTTCTGGACCTGGAGCGGCAATTCACTAACAAGAAAAC
+
??@1A?DD?AFFDBGGBAEDE;FHFEGGGGCEH4CH@DF>9?B3D<?@F>DBABDBGGGIICGHHC=D;EIEAEHCCBB:@BAC>CCCACCCC<CCCCC
@0KH
CTGACATCTCCTACATGCCTTCCTACCATGCCCACCAGCAGAAGGTGAACTTTGTCCCTCCCCATCCATCCTCCATGCCTGTCACTTCCTCCAGCTTCTTT
+
@?@=DDFF?C+AFFGGEHD@GHFHGG;BHGII>DEGGHHA;FADHCC9BFDG@HH>FEGIIIIICEHEHIFFDCEF@@BD>A:@CEECCCC?=CCCC3@@@
@0KI
GGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGC
+
@?;DDDDFHGHGGIJJIICHGHIHIIEHIIGGIG>FHGFBHGCGIEGGIEIIJJJIJGGIJJECCHHFDEECEACECCADCDDDCCDCA<@B9??CCCA
@0KJ
CTACACCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATGACATCTCCTGTGACTCTCACCTCTCAGACAACTAAGACAGATGACCCCCAATTGAAA
+
CC@FFDFFHDHDHIJJJJJJJIJJGHIGGIGIJ@FHDGHIJJJIIJJIIIJJIIIIIJJIIIIJGIJJGIIIIIHHCEEEFFDFFEEDDDDDCCCDDD
@0KK
CTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATG
+
CCCFFDDEHFDHDHIJGIBHHGIAHJIJJIGGCFHIIJIIGGIJIJJHGGEHHHFFFFFEECEE<CDDCCABD<BBDDDDDDCC>CCABDDDDDDDDDDDD
@0KL
GATTAATGGCAGAGTGCCTCAAAAAGAAAAGAGATGAGAGACCACTCTTTCCCCAAATTCTCGCCTCTATTGAGCTGCTGGCCCGCTCATTGCCAAAAATT
+
CCCFFFEFHHHGHIEGIJIJJJJJJJJJJJJIJIGIJIJJIJJJJIIJJIJJJJIJJJJIHIHIJFEFHFFFFFFECDCCDDDD=B@BDDEDDDDDDDDDD
@0KM
CGACGAGATTGAAATCGACTTTGAGACCCTGAAGCCGTCCACACTGCGTGAGCTGGAGCGCTATGTCACCTCCTGTTTGCGGAAGAAAAGGAAACCTCA
+
CCCFFFFFHGHHHJJIJJJJIJJJJJJIJJJJIIJIJHIIJJJIGIJJGIEEHHHGFFFCDDDBDDFDDDCDDDCACDDCBDBBBDDDDDDDDDDDDDD
@0KN
GGACAGTCGAAGAACTTCAGAAGAGAAATCATAAAGACAGCCAGTTCGAAACTGATATAGTACAACGAATGGAACAAGAAACACAAAGAAAGTTAGAACA
+
BCCFFDEFHHHHHJJIIIIGIJJJIEHJGIIIIGJIIIIIIIJJGIJJIHIJJJIIIIJJIIIJJJJHGHHFFFFFEEEEECCBDDDCCBDDCCDCCDDD
@0KO
CAAAATTTGTGCAGTGTTTAGCATTCTTGGGGAATGGAGATGTTCTTACTGGAGACTCAGGTGGAGTCATGCTTATATGGAGCAAAACTACTGTAGAGCCC
+
CCCFFFFFHHHHHJHIJJJJJJJJJJJJJJIJJJJJJJJIJJJJJJJJJJJIJJJJJJJJJHGIIJEHJJJIJHHHHGHFDFFFEEEEEDDDDEFDEDDDD
@0KP
CTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTT
+
CCCFFFFFHHHHHJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHHHHFFFFFFDDDDDDDDDDDDDDDCDDDDEDDD9><B
@0KQ
CCAAATACGGCTCCCTGCGGGGCTTCCTCCGCGAGAGCCGCAAAGTGGGGCCTGGCTACCTGGGCAGTGGAGGCAGCCGCAACTCCAGCTCCCTGGACCAC
+
<@@FFDDDFDFHFGGG<AFABEHIGIIFHGBEEEBCDDABDDDDD:CCDDB<<?B@CC?<AC=<BCB<CC:?B<?BBB@>B@D>CDAACCCCBC@BDB?BB
@0KR
CCTGTAACTCCTTTCCTCCTTTGCCGACGATGCCAAGGGAAGGACGTCCTATGTACCAACGCCAGATGTCTGAGCCAAACATCCCCTTCCCACCACAAGGC
+
@@@DDFFFHHFFHI>FGBHHGCHGGIIJEGCFHIGGIJJGGIJAGE;AGEE@EHHFA?ABBBBADDCCDDCCDACDDDDDDCDDDDDDDDDDBDDDBD@BB
@0KS
TCCGCTATTACTATGAGAAAGGAATTATGCAAAAGGTGGCTGGAGAGAGATATGTCTACAAGTTTGTGTGTGATCCAGAAGCCCTTTTCTCCATGGCCTTT
+
<@@DDFDDFFHHDIICHGIIIC?FHGGGECEDGGGGDCEGGHGGIFGIIIG@DGGGIIHGIIIGCHCGC?A@EFDEF@CACC@CCCCC>CCCCCCCBACCC
@0KT
AGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAA
+
@@@DDDDDFFBHHJJJJIGIEHGHHIIHIHDGHCFEFHGGCIGGIHGGFIEHHCE?DEEEEEAAC@CACCDDDCCCA??ABB?B???ACCCDDBDDDB?
@0KU
GGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACAC
+
CCCFFFFFFHHHHJJJJJJJJJJJJJJJFHIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJHHHHHFFFFFDDEEDDDDDDDDDEEDDDDDDD
@0KV
CACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGC
+
@@@DAAB?AFDDDB<ACGFC:F<;?E8C3<FH>:11?DB@@?99?*08?DD>C@;BA;@3.@@E:H>5;;>;=>@C@CCDD?8;@;<??B<<@5<?B4>@:
@0KW
GTCCATACCAGATAGCAGCTACCCCATGGACCACAGATTTCGCCGCCAGCTTTCTGAACCCTGTAACTCCTTTCCTCCTTTGCCGACGATGCCAAGGGA
+
@BCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJIIJJJHHHHFFEFFFEEEEEEDDDDDDDDDDDDDDDDDDDDDDDDDD
@0KX
CCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATG
+
CCCFFFFFHHFHHJJJJJJJJJJIJJJJJJJHIJJGJIJJIIJEHJJIIJJIIIJJJJJJIIJEHFFEDEEEEDEFEFDDDDBBDDDDDDDDDDCDDDDED
@0KY
TTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGC
+
@@@DDDFBDABDA<DGHGBEIIBEGIIIG@GGHIGHEHBEGGIEHIBFDHGGIGHGGEDCEGA>CE7?@DCBD@A;;6@;;AAACCD?CCACDDB?@DB<?
@0KZ
CCTGGCTCACTAACTAACGTGAAAGCCTTACAGAAATCTCCAGGACCTCAGCGAGAAAGGAAGTCATCTTCATCCTCAGAAGACAGGAATCGAATGAAAAC
+
?@@=DFDDHDAFFIEIIIDAFAA4CFGGG3CFHBDGGCGHI@E>B=GGCFHDDHAGGIGIGGC;CEHFCCCDFB3?AACEEEC?CCBBBCCBACCCCCCC?
@0L0
GAACACAACACCATGGTTGGCAGTGCGGCCAGCCAAAGCTTTCCCCCTCCTCTGATGATTAAACAGGAACCCAGAGATTTTGCATATGACTCAGAAGTGCC
+
CCCFFFFFGHHHHJJJHJIIJGJJIJJJIJIJJJJJJJJJJJJJJJJGGJHGHGEGFDFFFFFEDEDEDDDDDDDDDDDDDCDDECDEEDDDDDDDD@CCC
@0L1
CCTCCTCACTTGGATCCAGACATTTAATGTGGATGCACCATGCCAGACCGTGGAAGATTTAACGAATGGGGTTGTGATGGCCCAGGTTCTTCAAAAGAT
+
@@CDDBBEHFHHB?GHEEHEFHGHGIIGEHGH>DGFBGBF?DGGHDDB@DGHICHE@@FHCCEH@?E>>C=BAA8=5@;5;?B@BDDDDC@@>CACCBC
@0L2
CATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACT
+
@??DDDBBDHHHGGGB;AHHD?FHDC?FHFBHIG@FGIIAHBHIG?DBBBBBD?BFIF@@C=FH;===7==7;?C>@>;;;;;??8?A?8=BB@CCC>>A>
@0L3
CCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCT
+
@@CFFFFFDHHHHJIIIIJGIIJJJJJIIGGIIIJJJJJJJJJJJJEIJIJJJJJJJIJJHHGHHFFFFFEEEBABBDBBCCCCCDEDDDDDEDDDDBD@?
@0L4
GAGACATCAAACAAGAGCCAGGAATGTATCGGGAAGGACCCACATACCAACGGCGAGGATCACTTCAGCTCTGGCAGTTTTTGGTAGCTCTTCTGGATGAC
+
CCCFFFFFHHHHHJJJJJJJJJJJIJHIJJJJJJJJJJJJJJJJJJJJJJJJJJFDDDDDDDDDDDDDDDDDDDDDD?CDDDDDBDDDDDDDDDCDDDDDD
@0L5
ATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTT
+
CCCFFFFFHHHGHIJIJJIJJJJJIJJIJIGGIJJJIJJJJJIGIIJIGJIIJIJIJJIIJIIIJIIFHHHDDEFEFCEDDDDCDBBBBDDDDDCDEDDDD
@0L6
AGCTTCATTTGCAAAGAATAAATCCAACTACAGTGAAAATGAAAAGTTCTGTCTTTGATGAAGACAAAACTTTTGTAGCAGAAACATTGGAAATGGGGG
+
@@@FDFEAHDFHDGGGGGGGGIJIEHGHCG@EGFGCGHHFIFIEEGIIII>?FHHIGB<BGGGDFHHGGIGHED@=;=@DA?EFE@CDDD@ACE>CE(3
@0L7
CAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTTATGGGCAGG
+
@B@FFFFFHHHHHJJHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJHHFFDEDDDDDDDDDCDDDDEDDD9>@BDDDDDDDDDD
@0L8
GCTTGCCTTGGAAAGGTTTCTTCTTCAGGAAAACGGGCAAGAGAAGTGCATGGTGGGCAGGAGCAAGCCCTAGATAGCCCCAGAGGGATGCCCAGG
+
@@<DDDDB?FA8DDHI+A<FFHEE@<EE>EGH9C8CG<??;DG>GHBFEH@CF8CEBD3AB;1.;DD25;>AA:>>;AC?;@@9<?5598ACC:+2
@0L9
CACAGGGGATGCAGTCTCTGGCCGAGATGAAGCTCGTTCATCGGGACTTGGCAGCCAGAAACATCCTGGTTGCTGAGGGGCGGAAGATGAAGATTTCGGAT
+
;(0((22(0(2@;1@)@9)>)@?8-=((<7>?53)<571..<)'-'5>83.=.(5=?0..=3(.-(73(:(,8(:(,32&50:9::(:2:/+(:6<(+&(+
@0LA
CCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTAT
+
CCCFFFFFHHHHHJJJJJJJJJJJIJJIJJJJJJJJJJJJJJJIJJJJJIJHJJJJJJIJJJJIJIIFHHHHFFFFEEEEDEDDCDDDDDDDDDDDDDDDD
@0LB
TGCAATCTCTGAAGATCATGTGGCCTCAGTGAAAAAAATCAGTCTCAAGTAAAGGCCAACCAAGCC
+
CCCFFFFFHHHHHJJIJJJJIHGJJJJIIEFGIJJIIJJGIIHIGJJJJIIJIJJDGHGGHIJGDH
@0LC
CCCAGGTTGTTGACCAGCTTGCTTTGACTTCTTCAGCTAAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCT
+
@<@DDD=BBDHFADGGGHID9@HHIE9FH@EGGF@C4CDD@FD@FH<BFFGGHDHGAEC:/@GGG@?>CE3?EEEEDDEC@>CCC->;>>CC@(>CCCB5
@0LD
GCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCC
+
CCCFFFFFHHHHHJJJJJJIIJJJJJJJJJJJIIJJJJJJJJJJJJJJJJJJIGIJIJJHHHGFFDFFEEEEEEEDDDDDDDDDDDDDDDDDDDDDDDDD
@0LE
ACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGC
+
CCCFFADDDHFFHJFGHIIJEHEGHIIJIIJIJIJCHIIJJJGGIJIIJJFGIIIIJJJJHHGFFFCEEEEEDCDBDDDD:C@@@DDDD>>>CCDDD>C
@0LF
CCGAGACATCTACAGGGCGAGCTACTATAGAAAGGGAGGCTGTGCCATGCTGCCAGTTAAGTGGATGCCCCCAGAGGCCTTCATGGAAGGAATATTCACTT
+
???DDDD3<<?<DB:2CEEI<DDDEEIEEC<DD>>=D<<;CD6.=CC;=AA7??CADADA@D>>:A@AA??3;=?9<<8>AAA>:>:A><<>:A>>:+>>A
@0LG
GAAAGCGAGAGGGAGACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGC
+
C@CFFFFDHHHHHHJIJJJJJJJJJJJJJIJJJGIJGHJHIHHHGFFFEEEEEDDDDDDDDDDDDDDDDDEEDDDDDDEDDDDDDDDDDDDDDDDDDDDDD
@0LH
CTCCTCTGATGATTAAACAGGAACCCAGAGATTTTGCATATGACTCAGAAGTGCCTAGCTGCCACTCCATTTATATGAGGCAAGAAGGCTTCCTGGCTCAT
+
@<:DDDBDFHH?FHGIIIII;CA;FDBACGH4:???*?9D?BGHEGGIIG99??*<BDEIIE@78C;=@E@HI@C=A=????BDDAC;AC;;;;AC@9>5@
@0LI
CTGCCCTCTAAGGCTGTTGGTGTCAGCCAGGAGGGTCCTCCAGGCCTTCCGCCTCAGCCTCCACCACCAGTTGCTCAACTGGTCCCCATTGTGCCCCTGG
+
@?@DDFFFHHFBFGDGEEHHFGHHIGIGIIIGHII?DHIIIIGGIIGHIIIIIBHIGFHHHFEFFDDDDDADCDDDDDDCCC5>ABBCDCC+4@CDB?BD
@0LJ
CTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACC
+
CCCFFFFFHHHHHJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJHHHHFFFFFFEEEEEDDDDDDDDDDDDDDDDDDDDEDEDDDDDEDD
@0LK
AAAGTGGAAAAAACCTGAGAACTTCCTGATCTCTCTCGCTGTGAGACATGTCTGAGACTCCTGCTCAGTGTAGCATTAAGCAGGAACGAATTTCATATAC
+
CCCFDFFFHGHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIIJJJJIJJJJJJJIJJHHHHHHFFFFFFFEEEEDDDDDDDDDDDEEEFEE
@0LL
GCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGT
+
CCCFFFFFGHHHHJJIHIGHIJJJJFHIJGIJJIGIJJJJJJJGJJJJJJJJJJJJJIIIJGGJJJJIHHHFFDEDEEDDDCDDDDDDDDDDBDCDDDDDC
@0LM
CCATCCAGCACGCCAGTGTCCCCACTGCATCATGCATCTCCAAACTCAACTCATACACCGAAACCTGACCGGGCCTTCCCAGCTCACCTCCCTCCATCGC
+
CCCFFFFFHHHCFIGIJJIJJJJIJJJJJJJJIICHIIIJJIJJJIJJJJJJJJJJJJJJIJHHHFFFFFDDDDDDDDDDDDDCDDDDDDDDDDDDDDDD
@0LN
AGATAAGCAATTTAAAGAAAATTTTAAAAGGAATCTTGGATTATAATCATGAGATTTTAGGACAGCAAATTAATGACTTTACCCTTCCTGATGTGAACCTT
+
7;====32<22A=?4+22+3++<7A@=7<<2+11@B<A<**11:770::774***0=9//*?ABA9>;==)=7777.).77>>A3>7>@;(66...5(;5-
@0LO
CAACTACAGTGAAAATGAAAAGTTCTGTCTTTGATGAAGACAAAACTTTTGTAGCAGAAACATTGGAAATGGGTGAGGTTGTTGAAAAGGATACAACAGA
+
@@?DDDDAHA?AAGBGHII@HIICEHAHHHEGH<FEFGBEHEIIIEGEHGI?BFHGHIIIGIIIIIEGICFFG;ACCEA>EEE@DEC@ACBCC>@CCBBC
@0LP
GCACACCATGATTTGAATATTGATCAATCACAGTGTAATGAAATGTACATAAATAGTTCTCAGAGAGTAGAATCAACTGTGATTCCTGAATCTACAATAAT
+
@@@FFBDFHHHHHJIGIJIIHIJIJIJJJJJJJBGCGGGHIJJIJBGIIIIHHJFEGGIGCGHGEIG=FGGHGIJJJIDDHGJJIHHGGEHHFFFFFFEEE
@0LQ
CGAGAGGGAGACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTAC
+
@@@DDFFFFHHFHJIIIGGIGIEHHIIJGHIEIIFHIIIJGIFEEHEFFFFACBDDDDDBDDDDDDDDDDCDDEDDD@BD@CDDDDDB@DBBDDDD@BC
@0LR
CAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGG
+
C@CFFFFFHHHHFHIJJJJJJFJIJJIGGIIFIJEGGIJJIIJJJIFIJJFGJFJEGGDHGIJIGGGIHGHHHFFFFDBEABDDDDCDDCCDDDDDDDDDD
@0LS
GTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGC
+
C@CFFFFFHHHHHJJJJJJJJJJJJJJIJJJJJJJJJFHJIJIIJJJGHIGJJJJIJIJIHIJHHHHCEFFFFFEEECCEEDDDACCDDDDDDDDBDDD
@0LT
TGCTCAACAGGTATCATCTTTATCAGAAAGTGAGGAGTCCCAGGACTCATCCGACAGCATAGGCTCCTCACAGAAAGCCCACGGGATCCTAGCACGGCGCC
+
@BCFFFFFGGGHHHJJJJJJJBHHGIJIDGFHGJECFHIIJJJJBGGHHGGGGGIJJJHEHIJJIIHHHAHDDCFFCCCDDDDDD?=@CCDDDCCB@@DDD
@0LU
GTCATCTTCATCCTCAGAAGACAGGAATCGAATGAAAACACTTGGTAGACGGGACTCGAGTGATGATTGGGAGATTCCTGATGGGCAGATTACAGTGGGAC
+
;?@DDD>DF>FHHIFGEEEB;FHEGFHBG>F;EG@GBBFGCGGI>BGG?*?FE6;FCF@A)==EEHEHA;?BD/;>3;@CCCC>A?C8?CCCCCC5>CA8?
@0LV
CGGAGAGCAAGTGCAGCCGCGGAGCCCTGTACACAGGCTTTTCCATCCTGGTGACTCTGCTCCTCGCTGGCCAGGCCACCACCGCCTACTTCCTGTACC
+
@CCFFFFFHHHHFIJ>GHGHIJGIJIIJIIIJGIIGIIJIGJIJHHGHGFFCFFFFEEEDCEDCCBD@DDDDCDDDBDDDDBDBDDBBDDDDDDDCCDD
@0LW
CTTCTGAAGACCGGCCACCGGGTGGAGAGGCCAGACAACTGCAGCGAGGAGATGTACCGCCTGATGCTGCAATGCTGGAAGCAGGAGCCGGACAAAAGGCC
+
=<;=AAAACACCAAAAAC3=8)0?AAA95;<AABBAAA=AB)7AA==<@:=;=???>:88=-88;?7:?8;788(58:18?=;;<99;09;5;;;3;?=;;
@0LX
ATGAAATGAGTCAAAAGATAGAAACCATGCAGTTTGAAAAGGACAATTTGATAACTAAGCAGAATCAATTAATTTTGGAAATTTCAAAGCTAAAAGATTT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJEIJJJJJJJJJJJJIJJJJJJJJJJJJJJJJIJIHJIJJJJJJJJJJJJJHHHHHFFFFFFEEEEEEDDDDDD
@0LY
CTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGT
+
@@@FFFFFHHHGHJIIIBIGIIHHIJJJGIJIJIGGGIIHIJJJGIJIIEHIIJIIIGIJJIJIEGGHHGHEFFDFFDEDCBDDCDDCCCDCDDDBDDDD>
@0LZ
ATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCA
+
CC@DFFDFFHFHGII@GIIIEHGGIIII<DHAHGGGIFGIGIIBFGEHGCHIIEHAEEFFFBBDEDDCDDBCDDCDEDDDCDDDDBDBB?BBDDCDDDBD
@0M0
GAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACT
+
C@CFFFFFHHHHHJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJIJJJJJJGHIJJHHHHAEFFFFFEEEEEDDDDDDDDDDDDDDDDDDDDDD
@0M1
CCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCT
+
@@@DFFDFDFFDHGFGIIGHEEEHCCGHGIGHGCHGGDHIIGIGIIIIHIJJIEHGIEGHECCEDDFEDCCDD@BDC@DDDDDDB@55CCDACCDCD>ACC
@0M2
CATAAAGACAGCCAGTTCGAAACTGATATAGTACAACGAATGGAACAAGAAACACAAAGAAAGTTAGAACAACTCCGGGCAGAGCTGGATGAGATGTATGG
+
CCCFFFFFHHHHHJJIIJJJJJIJJJJIJJJHHIJJIJJJJJJIJJJJJJJJIJIJJJIJJJJHHIHHHHGHFFFFDDDDDDBBDDDDBDDDDDDC@DEED
@0M3
ACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCT
+
@@@FDDDDBHHHAHHHHIIHCDGGEHCE?EFEGIGIGCFGAHIGHIHGBFGGGIGHFGIIIGHIIGHGHGGDDFDFDEEECCDCDDBDDCDBDDCBACDDC
@0M4
TGACTGGACAGTTACCTTATTCAAACATCAACAACAGGGACCAGATAATTTTTGTGGTGGGACGAGGATACCTGTCTCCAGATCTCAGTAAGGTACGGAGT
+
;?;:A=B;;<ADDEEEEA<EF@3ACBDC+<2+1:E3CD18D;?@;*?DCDDEE(=BA=@5/.=A>>@/6>(5((5>>AAAA:(:>(,;(,,(:>(()5()(
@0M5
ATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTG
+
=1:4A??;?A:2211@8:C?CDD?0BDD;8DDA?DE>4BBC@7@C;=@7@@A?=?=?.?77?AD@@@@-5;A>5>85<=5:>???>?<>AA:28>4(4>>A
@0M6
TAGAGGGAAAGCGAGAGGGAGACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGC
+
@@CFFFFFHHGHGGHGHIJGIHIGIIIJIJIJJFIJJGHBHGBHFDFFDDDCDDDDDDDDDDBDDBCDDBDDDDDDDCDDCDDDDCDDDDDDDDDDDDD
@0M7
GCCGGAGTAGGCCTGGCTAATGCCTGCTATGCAATACATACTCTTCCAACCCAAGAGGAGATTGAAAATCTTCCTGCCTTCCCTCGGGAAAAACTGACTCT
+
?@@DD:DDHHFFHFGIIBHEHIIICEGEEHGCE>BDHFHHIGIGAHIGEGGHHGIIIFGHEGGIEEHHFFBEEEEEECCCCAC>ABBB@BA??@CC>CCCC
@0M8
GGGTGAGGTTGTTGAAAAGGATACAACAGAACTCATGGAAAAACTTGAGGTAACCAAGCGAGAGAAATTAGAGCTGTCACAGAGACTGTCTGATCTTTCTG
+
@@@?DDEFFHGDHEHHIGGHHIIDHIHHGIHHIGIHGGIIGDDHIIIGCD8BGGDHEGEECEBBCHFBEF;CACCE@ACCACCCDCC>CCCDACCCDDCCD
@0M9
GACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACAC
+
@CCDDADFHHHGGJJJJIGAGHCGHGGIIHIHGIHIJHIIIIGGHHHHFDDBCCECCDDDDDDDEDCDDDDCDDDDABDDDDDDDDDDDDCDCCCDDDDDD
@0MA
TGAAAATTGGCTAAACAGAATCAAAACTGAAGTAGGAGATAATTGGAGGCTAAAGATAAGCAATTTAAAGAAAATTTTAAAAGGAATCTTGGATTATAATC
+
@@CDDEFFA>FFFGBHGGEBHEHIIIGIIIGGCEGHGHGBFHGIIIIIIIHIIGGHIIGIIGIIIIIIGHIIIGFHHHFFFFFFFCC>@CECCACCCDDAC
@0MB
CTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCC
+
CCCFFFFFGHHHFIIGGIJIJIGJJJJJJJJJJJJJJJIJIIJJJIEHIGIAF?DHIIFHHFHFBDFFCEDDCCECDDDDDDCDBDDDDDD?CCDDDDB
@0MC
CAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTT
+
CCCFFFDDHHHGHJJJJGHIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJHHHHHHFFFFFEEEEEEECDDEDDCCDDDDDDDDDDD
@0MD
CTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACC
+
@@CFD?DDHHFFHIIIIEHH@GEHIHGIGGIBHI=FDGCHDDGGIIIIGHIIIGIIGEH<BFDCCECCC@>?CCCCACCEECC>C@BBCC@CCCCCCCCCC
@0ME
CAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCA
+
CCCFFFDFHFHHHJJJIJGHJIIJJJJHIJJJIJJIJIJJJIJJIIJJJJJJIIIJJJJIIJJDGIJJHHHHFFDDCDEDDDDDDDDDDDDDDDDDDDDD
@0MF
GAAGAAAGTAAGCAAGAACAGTTGTTTTTGGATCACTTACCATCTGTAACAAAGGAATCATCACTTAGAGCAACTCAACCAAGTGAAAAGGATAAACTTC
+
;;(5<;;9))@@1)94)))=?<>;)():3;())11.=)3))<>?)7=??3==>13=)=;>>)<;??;1)).=03=>8;9;5;(..(.5;((732,((5((
@0MG
CCTGACAAAATTAGGATTGCAACTGGACAGATAGCTGGCGTGGATAAAGATGGAAGGCCTCTACAACCCCACGTCAGAGTGTGGGATTCTGTTACTCTATC
+
@@@DD;:A;CCACG@CDGGBFDBCDE9?BFF>FGEBFB?@:@F=@FD8BBCBEC)8@FCDDG=@EAHFEEE@>????;>:5,:@B9>>@@ADCCCAA:>CC
@0MH
GATAATCAGCGTCCACTGCTGAAGACAGACATGGAACGTCACATCAACGAGGAGGACACAGTGCCTCTTTCTCACTTTGATGAGAGCATGGCCTACATGCC
+
@<@DFDEFDHGHHHI<FGIBA9BABBHIGGFI<?FF9?:BBDEFHGGHGIEGAA<CEC>.=7??7?@CCECECCECC:>;ACC>C@?CCCB<?CCCC@@C>
@0MI
CTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCT
+
@@@DA8:BFFHB<?EFHGCIIGHIHGEEHGEGID@B>G9FBFF>HIIFDBCEF@F>;DAC@CCEH@>?=CCAC3=;?A>@CCCCCBBBB?BA<>@?CCCCC
@0MJ
ATAACCGCCAGGATTGACAACCTCCCTATTGATTGTTTTCAAACTTCGAAATTTTGGAGGCTTTTTTATGGGTCGTGCTTATTTCCTTTCTGAAAGTCACG
+
(-7:9:5(-(-((2):))>=1;)2(())).0)))))0).)<3).)<6(;;5=).89')</(()).)376.-(7(',',,80::(85((5((+(((++(+(0
@0MK
GGGAAAGACAGAAAAATAATTCTGTGGGATCATGATCTGAATCCTGAAAGAGAAATAGAGGTTCCTGATCAGTATGGCACAATCAGAGCTGTAGCAGAAGG
+
@CCFFDFDHHHHHJIGIJJJJJJJHHIIJIJJJJGIJJGIIJJIJJJJIJJIJJJJIGHHJGHIIJIGIIIJHGIHGHFGFFDFFDDEEEC@CDCDDACDD
@0ML
CAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCC
+
@CCDDDDFHDHHHIJEEGGIHCHGGIJIJIGIIEHIIIJHFFHIFHI@C=DHIJJHEFED?BCCECCCDDDDDDDDBDCCDDDDDDDACDDCDDDDDCBD
@0MM
GCCAAACATCCCCTTCCCACCACAAGGCTTTAAGCAGGAGTACCACGACCCAGTGTATGAACACAACACCATGGTTGGCAGTGCGGCCAGCCAAAGCTTTC
+
@@?DDDDDDBFHDEEIGIIIIGHIG@GHIIIHIGGGGEFG???FEABFHIGFGHI7@DEFE?EEEFFBCBACCDCADDACD9@CBBDDDDBDDDDDD@@@C
@0MN
CCAACCCCGACGAGATTGAAATCGACTTTGAGACCCTGAAGCCGTCCACACTGCGTGAGCTGGAGCGCTATGTCACCTCCTGTTTGCGGAAGAAAAGGAA
+
@@@D?DDDHDA?F@CD>FEGG>DHGEEHD9BHGHGIGEGA)8C@;;-5=B?@CDC39??CCCC????@8@;>44>CCCBB?C@CCA:<BB@5<A?CCBBC
@0MO
CCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATT
+
@CCFFFFFHHHHHJJJGHFIIJJGJIJJJGIIGIFGHG?CGHHHIGGHIJJJJJJJCHIIHIFGGEGHIHHFHH@DFFBCEEDEEBDAADCDDDDDDCCCC
@0MP
ACGGAGTAACTGTCCAAAAGCCATGAAGAGATTAATGGCAGAGTGCCTCAAAAAGAAAAGAGATGAGAGACCACTCTTTCCCCAAATTCTCGCCTCTATTG
+
CCCFFFDDHHHHHJJJJJIJJJIJJJJIIJHIJJIIJJJJJJJFHIJJJJJJJJJJJJJJJJIJIJJIGHHHFFFFFDEEEEEDDDDDDEDDDDDDDDDED
@0MQ
GGGAAATATGAAAAGCCAAAATTTGTGCAGTGTTTAGCATTCTTGGGGAATGGAGAGGTTCTTACTGGAGACTCAGGTGGAGTCATGCTTATATGGAGCA
+
@<@DDDD>?FDDAGHG?;EGE:CF@<222<<?1?F?BEFGE9?FGIIA?FHGI<@8(-B=CCHF:7@G.@DC>E3=?7;5=A6;;(>-;5>>@@>@:992
@0MR
ATTCACTAACAAGAAAACAGGGAATTTTTGGGAAATATGAAAAGCCAAAATTTGTGCAGTGTTTAGCATTCTTGGGGAATGGAGATGTTCTTACTGGAGAC
+
@CCFFFFFHHHHHJJGGHIIJJJFIJJJGJJJJJIJJIJJJJJJJIJJJIIJJIHIJJJJJIIIGJJJHHHHHHHFFDDDEEDDDDDDDDEDDDDDDDDDD
@0MS
CTGGGAAGCAGCATGAGATTGAAGAGCTAAACAGAGAGCTGGAAGAAATGAGGGTTACCTATGGGACTGAAGGACTGCAGCAGTTACAAGAATTTGAAGCT
+
@@CFFFFFHHHHHJIJIJJJJJJJJJJJJJJJJJGIJJGIIJJIIJJJJJJJIJGIIJJJJIIJIIJHHHGHFFFFFDEECCDCDDDDDDDDDDDDEDDCD
@0MT
GAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCC
+
CCCFFFFDHFHGHIJHHJJIIJJDHIIHGIJJHHHIJJIGIJJJJIIHIIHHHHHGFFFFDDCEECA@BBB?BDDDDDDDDDCCDDDDDDDDB@BBBDDDB
@0MU
ATGAACACAACACCATGGTTGGCAGTGCGGCCAGCCAAAGCTTTCCCCCTCCTCTGATGATTAAACAGGAACCCAGAGATTTTGCATATGAC
+
@CCFFFFFHHHGGJJIIJHGJGIJJFHIIJJJIJJIIJJJIJJJIIJIIEHHHFHFFDEFFFEEEDDEDDDDDDBBDBCDDDDDDEDCDEDC
@0MV
GTTAAGAGGAGAGACTACTTGGACCTTGCGGCGTCCACTCCATCTGACTCCCTGATTTATGACGACGGCCTCTCAGAGGAGGAGACACCGCTGGTGGACTG
+
@@@FFBBDHDHFHE@GIHIGIIIGIIIHFB@DDHG<GGIGGGIIIIIIFFEFEFDFFFFECEDCD>BDDDDDCCDDDDDDBDBBDDCCB@DD>BACBBDDA
@0MW
CCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGG
+
=?1+=B;BF;F<AFFFF?EFGI9D>FBE>BFEEBGDFGBB@)=;@;CCCC9=@E@3?A=A>C)?@B36;>;A;6===@@B)&2>ABBB?8?@B1(2<94+>
@0MX
GTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGC
+
C@BFFFFFGHHHHIIIGIIJJJGJJIJJJJIJJJJJIGHIIJIGIJJJJJJJJJJIIIIIJIIHHHHFFFFFFFEE>CEEEDDB>C?CDDDDDDDDDDD
@0MY
GAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTC
+
@@@DDDFDDFDBFFHGGGGGHHJCEDFHGHHGIIDG@AGFHIIIIDHFIJGIGFHHHFFFFFEDDBDDDBB?BDDDDDCDDEDDCCDD>BDDDBDBDDDBC
@0MZ
TTGCAGTGTTTGGAGTTCAACCTCTACATCCTCCTGGTCGTCTTTGGCGGATGGGGCGTGGGGCTGTTTGCAGTCGCTGTCGGGGCAGAGCTTGTTGTGGG
+
--((2)@)@)>>(8>2)))));)@@)=)=??1=@).)..(-((0<).</''-'(.('','''&&&&(+82:(:((&&)8)+(5&0&&&((++((8(((((*
@0N0
CTCTATCCAAGCCTTCCCTAGGTGACCGCTCCAAAATTTCCAAGGACGTTTATGAGAACTTCCGTCAGTGGCAGCGTTACAAAGCCTTGGCCCGGAGGCAC
+
@C@FDEFD?HABHHHIJEEHIGCFHGIGGGGI@FHGCEEC>GID=HII;;FGCGG>EEHGE@EE.6?B7;B=CC@:?=8<ACD9?A>CCA9:AB@9<BBDB
@0N1
GTACTTCTGATGTTCAAGATCGCCTGTCAGCTCTTGAGTCACGAGTTCAGCAACAAGAAGATGAAATCACTGTGCTAAAGGCGGCTTTGGCTGATGTTTTG
+
?@@DDDFFHHHADGEGGHEDFHBFE;EHGHIGHEG@FHDFGDFHFFG>DGEGICGGEGHGIE;FGHGGGIGHEEHFFFFDCFDD@?@C@AD>@8:A:>>A2
@0N2
GATGACACCTGTGTTGTCCCAGAAAAATTCGATGGAGACATCAAACAAGAGCCAGGAATGTATCGGGAAGGACCCACATACCAACGGCGAGGATCACTTC
+
CC@FFFFFGHHDHGHIIIJJJJIJJJJIJJJIJJIIIJIJIJJJJJJIIIIJJIJJJJGI@GCGGGHHFFFEDDDDDDCCDDDDDDDDDBDDDDDDDDDD
@0N3
GGAAAATTCAGATGATAGCCGTAATAAATTGTCGAAAATACCTTCAACACCCAAATTAATACCAAAAGTTACCAAAACTGCAGACAAGCATAAAGATGTC
+
@C@FFFFFGHGHHIJJFIJIGFGIJIIIJIEGGHIJJJIIIIJJIJJIJJJGIIJIJJJGIIGIJIEEACHEDFFFFEEEEEAAABDBDDCDDDDCCC>C
@0N4
CAGCTCACCTCCCTCCATCGCAGTCCATACCAGATAGCAGCTACCCCATGGACCACAGATTTCGCCGCCAGCTTTCTGAACCCTGTAACTCCTTTCCTCCT
+
CCCFFFFFHHHHHJJJJJJIJIIFHIJJJJJJJIIJIJIJIJJJJIJJJJIJJIJJJJJIJJIIHHFDDDDDDDDDDDEDDDDDDDDEDDDDDDDDDDDDD
@0N5
GACCAATCCTCACGATTGAGTGTCAAAGAAGACCCTTCTTATGACTCAGTCAGAAGAGGAGCTTGGGGCAATAACATGAATTCTGGCCTCAACAAAAGTCC
+
@@@FD=D?HH>DBFGG=FH@CCCEAHIGHCCGBGHEHIGH@HEHHEHICHHDEHGIIFB=FCF>DGEFFEDDFFDCAC;>CCCCECCCCCCC<ABB?:ACC
@0N6
CTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAAC
+
CCCFFFFFHHHHHJJIIJJJJJJJJJJJJJIJJJJJJIIJJJJJJJJJJJJJJIJJJJJIJJJIJJJJIHHHGFFFFFEEEEECDDDDDDDDDDDDDDDD
@0N7
GAGAGATATGTCTACAAGTTTGTGTGTGATCCAGAAGCCCTTTTCTCCATGGCCTTTCCAGATAATCAGCGTCCACTGCTGAAGACAGACATGGAACGTC
+
3;<;99<=8<:@?:=)9..269(.263.=8=<41<<1=<7).<<8)7:>??17<3=?81;>9;998>=))3-;==>?;;3688=8=>?5<;>>8<:2576
@0N8
AACATCCCCTTCCCACCACAAGGCTTTAAGCAGGAGTACCACGACCCAGTGTATGAACACAACACCATGGTTGGCAGTGCGGCCAGCCAAAGCTTTCCCCC
+
@@?DDDDDDHHHHICGEHIGHDH<EFC?CDB?GGCFBFHGGEG6DFFG@FGFAAG>EIIF(5??BB?@CC;>?BCCB9:AB@@><1<?BCCCCC@CCACCB
@0N9
TGGAGGAAATGAAAACACGGCATAAGGGAGAAATGGAGAATGCTTTAAGGTCATATTCAAATATTACAGTTAATGAAGATCAGATAAAGTTAATGAATGTG
+
CCCFFFFFHHHHHJJJJJJJJIJJJIJJGHIIJJIGIJIJJJJJJJJJJJFHIIIJJJJJIIJJJJHHHHGHHFFFEFFEEEEECDDDDFDEEEDDDEDDE
@0NA
CCGAAGCCATCCAGCCCCCGGCAGGAGAGCACACGCGTGATCCAGCTGATGCCCAGCCCCATCATGCACCCTCTGATCCTGAACCCCCGGCACTCCGTGG
+
CCCFFFFFGHHHHIJJJJJJJJJJJJIIIJJJJJJJJHHFFFFFFEEEEEDDDDDDDDDDDDDDDDDDDDDDDDDDEDDDDDDDDDDDDDDDDDDDDBDD
@0NB
CCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACA
+
CCCFFFFFGHHHGJIIJJJJIIJIIIJJJJJJJJJIJJIJJJJJGHIJJIJIIIIJJJJIIIIJJJJJGHHHGFFFFFEEECEDDDDDDDDDDDDDDDD
@0NC
GCCAAAGCTTTCCCCCTCCTCTGATGATTAAACAGGCACCCAGAGCTTTTGCATATGACTCAGAAGTGCCTAGCTGCCACTCCATTTATATGAGGCAAGA
+
++=AAA3=27,+<7?A0?<3A4?<?4<21*:*113:)))005=A<**9=0*))8=AA48=>B>>B>>A73;==).7>67>;>@@@;=>;;((5=5(8959
@0ND
GATCATGTGGCCTCAGTGAAAAAATCAGTCTCAAGTAAAGGCCAACCAAGCCCTCGAGCAGTTATTCCCATGTCCTGTATAACCAATGGAAGTGGTGCAA
+
CCCFFFFFHHHHHJJJHIJJJJJJJJJJIJJJJJJIIJJJJJJJJJJJJJJJJJJJIJJHHHHHHFFFFFFEEEEDEEDEEFDDDDDDDDDDCDDCDDDD
@0NE
CTCTGATGGACAGCAGATACTTGTGCCCAGCAATCAGGTGGTCGTACAAACTGCATCAGGAGATATGCAAACATATCAGATCCGAACTACACCTTCAGCT
+
@@@DDDDDDFHDDIIH@DEA?D?+ABFGECGICB<FGGDFD0BFGGGBFGGGHIHID>FFDH@C@=@EAE?C@BC>C>CCCAC??BBBCCCCCCCCCCCA
@0NF
GTTTGTTGGCAGAGAATCAGGGATTAATGGAAAGACTCAATCAATCTGATTCTATAGAAGACCCTAACAGTCCAGCAGGAAGAAGGCATTTGCAGCTCC
+
8=?DD2BD8DB?AEE;CB4AC+2+9+2*?E3*18?9**BD<**0?09DB4/?D*9?BA<.).)(====;C7@333)..6?9(66;@?>;>;35>A>(5>
@0NG
AGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGG
+
@@@FFFDFGHGHGJGIIJJJIHJBHHIIIIJFGJAGIGIIJJHAHADHIE?FEHIJGEEHGH@CHEHEFEEEFEFCCDEEEDCDDD<CBCDDCDDCDDC@A
@0NH
AGACAAGCTGCAGCGCAGCAGGGCTACAGGGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAAC
+
(7(2(2(())):).2(:((6;>=6<>:??)-(0.0)97.-'-'573((:=5377996(.(3(-:7;(9((85/25-(8(((3:;/2-(26:77;<:66(6(
@0NI
AAATGTTTATGCGCGGTCGGCCAATTACCATGTTCATTCCTTCCGATGTTGACAACTATGATGACATCAGAACGGAACTGCCTCCTGAGAAGCTCAAACTG
+
CCCFFFFFHHHHHJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJIIJJJJJHHHHHFFFFFFFEEEDEEDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDD
@0NJ
CGCCAGTGTCCCCACTGCATCATGCATCTCCAAACTCAACTCATACACCGAAACCTGACCGGGCCTTCCCAGCTCACCTCCCTCCATCGCAGTCCATACC
+
:1=BDDDDDHDHFIIGHEHCFFBHFEFGIGEHEIGGEBDFFGHEFDDFBDFHEAFCGGEGIFEEAAA@A?CAB@CCCBCBBBCCBCA@<??B?ACCECCC
@0NK
CTACCCCAACCCCAACGTCCCCCGCCATCCTAACACCCACGTGCCTTCACACTTAGGCAGCTACTACTAGAAGCTTACTCATCAGTGGCCTTCTAGCTGA
+
=?@DBDBFHHGDHAFGGGEGIIIIFHGGEFEHIIIIIIIDIEHHHFHHGFDFDFCEEEEDDDCCCDDCCDCDDDC@CC>ACCCDDACDBACCCC@@CDAC
@0NL
CCCAGAGACTGCACACAAAAGCTCTTTCCTGTTTTCTTATCCCATGGCTTCGTTCCTTGCCCCGCCTGAAGCCCACAAGGACCCTGGGGGGGGGCCTCCC
+
;8(-58().))))))(-(22)(2.@>)=.)9>:973=6)2;>7))))(9()-<)9=3=>)<;(''',(.)(6=(((((,((73((72()0&)05&)228+
@0NM
GGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCAC
+
?@<BD;BDD+<CFC?;@BFEFI??@HHIECEE?GF9?F@F))???DA?FB?FCF@FCFE7@@CDEEEE?<>B>3>A>AA3>ABBB;;@BB5>??8?B<?32
@0NN
CAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCC
+
CCCFFFFFHHHHHJJJJJJJJJJGHHIJJIJJJJJJJJJJJJJJJJJJJIJJHHHHCDFFFFFEEEEEEEDDDDDDACDDDDDDBDDDDDDDDDDDDDDDD
@0NO
GGAAACCTCAAGCTGAGAAAGTTGATGTGATTGCCGGCTCCTCCAAGATGAAGGGCTTCTCGTCCTCAGAGTCGGAGAGCTCCAGTGAGTCCAGCTCCTCT
+
CCCFFFFFGHHHGJEGIIJIJDFHJJJIIGHIJIGEHGAFGIIGIIJGJIJIJIIIIJJJIDEEHDFFFFF;@BDD?;BBDCDCD@CACCDDACDDDDDDD
@0NP
CTCCTACATGCCTTCCTACCATGCCCACCAGCAGAAGGTGAACTTTGTCCCTCCCCATCCATCCTCCATGCCTGTCACTTCCTCCAGCTTCTTTGGAGCCG
+
CCCFFFFFHHHHGJJJJJJJJJJJJJJJJJJJJJJJJJBGHIJJJJJHIIJHJJJJIJJJJJJJJJJIIHH;EFFFFFFFEEEEEEDDDDDDDDCDDDDDD
@0NQ
CTCTTCTGGATGACCCTTCAAATTCTCATTTTATTGCCTGGACTGGTCGAGGCATGGAATTTAAACTGATTGAGCCTGAAGAGGTGGCCCGACGTTGGGGC
+
@@CFFEFFHFHHHHIEHIIGJJJIGGGGIIIIGDIHDEGIIEGHCGBFE<@GBGGGGGGGIIGHIGIHEHHFHFFBEDEEEABB@??ABDBD@@BBDDBDD
@0NR
CCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACAC
+
@@<DD>DD?<FHHA<AGHCHDHCHCE@FEHII<ECBFDDB>B?DGEGHIE4BF>FB<F<=@FAAE'57.77..?>A6(>AA>=-;;A55:>@>AC99?ACC
@0NS
CCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCG
+
CCCFFDFFHHDDFHIJJJJJIJJJIGEEGBE@FAHCHCGIIIIJIGJJJIGEHIGIIIJCFGGGIB@EEEFFFFFDC;AEDDDDDCDDC>?>:CDDDCCCD
@0NT
ACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGC
+
@@@FFDDFHDHHHJJJJJJ+AHHIJIJIHICHIJDHIIIIJEGIJJIIGIIJJJJIGIJIJIGDDGIGHEHHFEFEDEECDACDDCCCCD@CDCDDDDDD
@0NU
CTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGT
+
<?@DDFFDHHHHBHGHGIIIGIIIGB@GIGGIIIEGHGHIHGIHIIGIIF<BGFFFGIIIGIIGGIIHGFHHEDBCDCEDDBDDDBDDACDDDDDBCDCB:
@0NV
AGTGATGATTGGGAGATTCCTGATGGGCAGATTACAGTGGGACAAAGAATTGGATCTGGATCATTTGGAACAGTCTACAAGGGAAAGTGGCATGGTGATGT
+
@@@DDFEFGHHHGIJGHIIJJJJJJJJIJJHJIIJJIDGIGGIGGEGGGHGIJIIGCGGCHHEFHIGGEHIFHHHEFDFFEEDABBBACC?CDDD:@:@CB
@0NW
ATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCA
+
CC@FFFFFHHHHHEFHJIIJIJHJJJJIIHHIJGJIIJIGGIIIJJGGHHIIJJJGIJEHGIJJGJHHEFFFCCE@CACDDDCDCCDDDDDDDDDDDCDE
@0NX
GCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTAT
+
@@@ADDDDAFFFF@GFF9C<<FD>B<FEHHIIIIFFIFF1?CGD?B??B<BDBFFEC=FF<CAFEI7DEEEFFCD;;BD@ABC@@@@?:?BBBBBBB?AAA
@0NY
TGTACAGTCATGTGATACTCAAGTAAGCTCTTTATTAGATGGAGTTGTGACTATGACAAGCAGGGGTGCTGAAGGATCAGTTTCTAAAGTAAATAAAAGTT
+
CC@FFFFFGHGHFHIIJJJJGGIIGJJJJJJJJJJJIIHGIJGIFHHHIGIJEHJHIJJJIFFIJJAEHIHGHHHDFFFFFEEACDECD>;@ADDDCDD>C
@0NZ
GAAAACTCTTGAGCTAAAGGATAAATTAACAACTGCTGATAAATTACTAGGAGAATTACAAGAACAGATTGTGCAAAAGAACCAAGAAATAAAAAACATG
+
CCCFFFFFHHGGHJJJJJJJJJJJJJJJIJJJJJJJJJJJJJIJJJJJJJJJIJJJJJJJJJJJJJJJJJJHIIJJJHHHHFFFFFEEEEEDDDDDDDDD
@0O0
GTCATGCTTATATGGAGCAAAACTACTGTAGAGCCCACACCTGGGAAAGGACCTAAAGGTGTATATCAAATCAGCAAACAAATCAAAGCTCATGATGGC
+
C@@FFFDFGHHHGJJJJJIJJJIJJJJIJIIIIJJJJJIJEHIJJJJJIJIIJJGIJIJ=CBGHGIJIIJJGHHHHFFFFDEEEDEDDDDDDDDCDDDD
@0O1
CTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJHHHHFFFFFEEEEDDDEDDDDDDDDDDDDDDDDDDEDDDDDDDDDDDDDDD
@0O2
CTCAGGGAAAGTTCACTGCTGGCCTATAATACAACCTCCCACACCGACCAATCCTCACGATTGAGTGTCAAAGAAGACCCTTCTTATGACTCAGTCAGA
+
CCCFFFFFHGHHHJJJIJJJJIIJJJIIJIJJJJJJJJJJIJIJJJJJJJJJJJJJJJHHEHFFFBDEEEEEDEDDCDDDDD?CDCCCCDACDDDDDDD
@0O3
TTTGAACTCAGGGTCACCACCAGCTATTGGACCTTACTATGAAAACCATGGATACCAACCGGAAAACCCCTATCCCGCACAGCCCACTGTGGTCCCCACTG
+
@@@D?D3AFCFFHACGDHGGACE?CEDHGI@BGHIIGHEHEBD?GEGIAGGDHIIIICGIGIGFEH>?DCBCCC?>=?B=BAA?<A?8@:><CCCBBCBBC
@0O4
CAAAACTTTTGTAGCAGAAACATTGGAAATGGGTGAGGTTGTTGAAAAGGATACAACAGAACTCATGGAAAAACTTGAGGTAACCAAGCGAGAGAAATT
+
@@CFDDFDHFHH>CGHGGHIIIIIHGDHHIIHIE@GDD:?DDDFHIGIIICEFDHGFHIGHIGHG@DEA@EEFHFEFCDE3>CEECBB=@?@BC<C>>C
@0O5
CTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTAT
+
@@<DDDDDHHFHB@EHBBBF@HCHEHDGCCFGGDFBB?FAG;;C7@@HGEGFEHHEA>B>@DC;>;;?B=>@CCCA@@CCCCC@<<AABBBBB?BCBBCC@
@0O6
TAACTCTCAAAAGGAAAAACTCAAGGAAGAACTAGGACTAATTTTAGAAGAAAAGTGTGCTCTACAGAGACAGCTTGAAGACCTTGTTGAAGAATTGAGCT
+
?@@DFABBCFHAFE@AGEHGCF<CCGAF;CGEHFICDDGIDDFHGIGFHGI>DHG8CFFHHCE@@FCEGIEGEEEHF>B@EDCCAECCB>;;;?>>:>C@A
@0O7
GCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATAC
+
88?DBDDDB:DHFGG>;28CE>EG<<?*:DFGC@BGGGCABFEFD(=C;C@GE9CEE?AAB;@@;@;@A>@BCA@>;::@B95???(44@C>AD@@C4:@4
@0O8
CCAGGAGAACAACCACCAGGAGTCCTACCCTCTGTCAGTGTCTCCCATGGAGAATAATCACTGCCCAGCGTCCTCCGAGTCCCACCCGAAGCCATCCAGCC
+
@@CFFFFDHHHHGJIJJJJIIIIIJIJJJJGIGIIIIHFHFIIIJJHJJIIIIIJJIIGGIJIJJGHHHGFFFDDDDBD@CCDCDDD@BDDDDDDDDCCDD
@0O9
GTTCCTTGTATCATTCCGTCCAGTTGCTCTATCTCCACACTCCTGTTCAGCCCAACCACTCCCACTTCCCTGCAGACAAGGCGGTGCCTTGGTTTGTTTAT
+
+=:D:=2=C:?F?<,C:<3CGGFC?<F9CH<221*1::111:??:*0B9?9?F@@/-BBF@@=7=6C=7@37677)(;).6.',;2'9:ABAA?88+93:4
@0OA
CTTGAAGACATGTTGAAAATACATACTCCTGTTAGCCAAGAAGAAAGATTGATTTTCTTAGACTCCATTAAGTCCAAATCCAAAGACTCTGTGTGGGAAA
+
@@@ADFFDHFFHHJJJIJIGHHFHGIIGCAGHHGGCGHFF>FC@AHHIIIEIEIJHGGIJEIIGGICGGIJFFHGIIGGGHHGHHFBCEDC@@@ABDBDD
@0OB
CCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGACCCATGGATGAAGGACCAGATCTTG
+
??1ADD?D:DB<<CEB3CEB3<2<AFE;?*?:?;DDD0BB<@9?DD9?=DCA@;.BCDAADEEAD:<@6=2>;>>=>?<A<3>>AAA>5(8<??>:>33+
@0OC
CTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCT
+
CCCDDDFFDFHHGIGIJGDGIGHGBHGGGCGEIJIGIHCGIII>FEGGIEEGIJGIHIBGHFEFFCDCEDDDDCDDDBDBCCCDDCDDDCCDDDCDDDDDC
@0OD
CTCAAACTGGAGTGGGCATATGGTTATCGAGGAAAGGACTGTAGAGCTAATGTTTACCTTCTTCCGACCGGGGAAATAGTTTATTTCATTGCATCAGTAGT
+
CCCFFFFFHHHHFHIJJJJJJJJHJJJJJJJJJJJJJJJJJHIJJJJJJJJJJJJJJJJJJJJJJJJHHFDDDDDDDDDCDEEDDEEEEEDDDEDDDDEDC
@0OE
CGGATAATGACTCAGTGCTGGCAACATCAGCCTGAAGACAGGCCCAACTTTGCCATCATTTTGGAGAGGATTGAATACTGCACCCAGGACCCGGATGTAAT
+
@CCFFFFFHGHHGJIGHIIIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJGIJJJIJHIJHHHHFFFFFFEEECEEDDDDDDDDDDD@DD@DED
@0OF
CAAGGCTTTAAGCAGGAGTACCACGACCCAGTGTATGAACACAACACCATGGTTGGCAGTGCGGCCAGCCAAAGCTTTCCCCCTCCTCTGATGATTAAAC
+
CCCFFFFFHDHHHIIJIJJIJJJJJJJJJIJHHFHIJJJJJJIIJJJJIJJJGGIJJEHHHHFFBDDDDBDD?CDDDDDDDDDDDBDDCDDECEDDEDDD
@0OG
CTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCT
+
CCCFFDFFGHFHHJIJGGGIIIIGIJEGHGGHIIE7DBCGHIHIIG@DHIEHHFEHFFFDFFDDDCCEDACCDDCDDCBDDBBBDDBBDCDDDDDCDDCCD
@0OH
CCAATGGAAGTGGTGCAAACAGAAAACCAAGTCATACCAGTGCTGTCTCAATTGCAGGAAAAGAAACTCTTTCATCTGCTGCTAAAAGTGGTACAGAAAA
+
B@@BDFFDFDFHHFGIIJJJJJIJJJJJJGGHIJJIIIJJIIIJJHGJJJJJJJJJIIIJJJJIJJIIJJJIHHHEHHEFFFFFEEDC;@C@CDCECDDD
@0OI
CAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCG
+
CCCFFFFFHHGHHJIJJJJJJIJJJJJJJJIJJJIJJJIJGIIIIGIIGIJJJGIJJJJGIJJIJJHHHHFFFDFEEEECDDDDDBDDDDCDCCCDDEEED
@0OJ
AAAACACTTGGTAGACGGGACTCGAGTGATGATTGGGAGATTCCTGATGGGCAGATTACAGTGGGACAAAGAATTGGATCTGGATCATTTGGAACAGTCT
+
CCCFFFFFHHGHHJIIJJJJIJJJHIDHGIJJJJJJJJJGIJJJJJJIJJJJJJHIIJIIJHIHHHHFFFFEEEDEECDDDDDCDDDDEEEDDDDDDDDD
@0OK
CTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGC
+
@@@DDDD8CCFHHCGG:?FHDEG<FGE3C<CCDHC9DG=GHIBF>FGGGEGGIIA@FDF@D?DGEE7?ED;;;CE;;;;;@CC;>===<?C>@:9<9?AC
@0OL
GTGATGACATCTCCTGTGACTCTCACCTCTCAGACAACTAAGACAGATGACCCCCAATTGAAAAGAGAAATAAGGTTAATGAAAAACAGAGAAGCTGCTCG
+
1::B+ADD<B=?CBB9<?CECEF>3A@<C222+?*:BD?DE>BD<DC4?BDEDDDD;BC@DDCEA=A@C;CCD:?);;;);@AAA@>>9AA(,(3,(:5,5
@0OM
AAAAAGAAAAGCACAAAAGGAAAGAGGAAGTGGAAGAGAATAAAAAAAGCAAAGCCAAGGAACCTCCTCCTAAAAAGACGAAGAAAAATAATAGCAGCAAC
+
CCCFFFFFHHHHHJJJJJIJIJJJJHJGIJDGIGIJIIGJJJJJJJJJJIJJJJHHHHHFFFFDEEDDDDDDDDDDDDDBDDDDDDDDBDDEEDDDDBDDD
@0ON
GCAAAGTGGAGGAAGAAGCGAATGCGCAGGCTGAAGCGCAAAAGAAGAAAGATGAGTCAGAGGGCCAAGTAAACCGCTAGCTTGTTGCACCGTGGAGGCC
+
:?1AB:=+2=C?BEE9CEE>EA6:??@?@DD@DC*/?@6A@@;ACDCC??7?>;@@7(6(6;>'3;1<?,:>AA?60&05:>(9<((4>>A>1+&(2888
@0OO
CAGAGAGTAGAATCAACTGTGATTCCTGAATCTACAATAATGAGAACTCTACATAGTGGAGAAATAACCAGTCATGAGCAGGGCTTCTCTGTGGAACTGG
+
CCCFFFFFHHHHHJJJJJJIIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIIJGIIJJJJJJJJJJJJJJIJJJHHHFFFFEEEEEEEDDDDDD
@0OP
CAGGACCTCAGCGAGAAAGGAAGTCATCTTCATCCTCAGAAGACAGGAATCGAATGAAAACACTTGGTAGACGGGACTCGAGTGATGATTGGGAGATTCCT
+
CCCFFFFFHHHHHJJJJIIIJGJHIJJJJJJJJJJJJJIJJJIJJIHIJJJJJJIIJJJJJJJJJHHEHHHFFFDBDDDDDDABCDDDFDDDDBDDDDDED
@0OQ
GGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGC
+
@@?DDDDDHFDHFIBDFFEHHF@FGCCGCH@AFCFHGGEGGHIIIFGGEIIG@GI>BEEDBE?==BBCCCCC?ACACCACCC??<??@BBB@BBCCCCCBB
@0OR
GAACCCTGTAACTCCTTTCCTCCTTTGCCGACGATGCCAAGGGAAGGACGTCCTATGTACCAACGCCAGATGTCTGAGCCAAACATCCCCTTCCCACCAC
+
?1?D;@D;?FF8CDFFFB<EBACEHFE@HIEEGICG;9BBDFFECBEAFE@/AAEEE7;B@B>=BCBB?9AB;ADB@>>AB<9??BBB?238<(<A@<BB
@0OS
CCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGC
+
@@@DD=BDD?F8??EFIEICFFDBFFI@E@CBDCDG@?GBGDGIGEIIF?BFCF=FFFFEAECEEEEFCEA>BBDDD>;=@@@:;BA5>A;AB>A>>443
@0OT
CTTATTCAAACATCAACAACAGGGACCAGATAATTTTTATGGTGGGACGAGGATACCTGTCTCCAGATCTCAGTAAGGTACGGAGTAACTGTCTAAAAGCC
+
@@@DDDDDHHHD?BEDHHG=EGACHFEHIIBHF>GIDHIIII@GHGIIIIIIIBHHIFHEECH@DBEECDCCC@C>>;(;;>@?:8CCC>@>ACDCCC><A
@0OU
CAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAAAGTTCATTCCG
+
CCCFFFFFHHGHHIJJJJJJJJJIJJJJJIJIJJIJIJJJJJJJJJIJJJJJJCFGIIIIIIIIIJHHHHFFFFFEECEEDDDDBDDDB3?ACCDEEEDEC
@0OV
ACTTCCCTTGTGGGAATGTCAATTACGGCTACCAGCAACAGGGCTTGCCCTTAGAAGCCGCTACTGCCCCTGGAGCTGGTCATTACGAGGATACCATTCTG
+
@@@DDDDDHBC?DHG@DHBAFHBE?H=?:@DGEHIII>FH9DCDG@F<@DHG=FGGEIIIHE<?C;@6;=@B??BCBCC<CCCD>C@7>>>CC:@CCCDDD
@0OW
CCAAAAGCCATGAAGAGATTAATGGCAGAGTGCCTCAAAAAGAAAAGAGATGAGAGACCACTCTTTCCCCAAATTCTCGCCTCTATTGAGCTGCTGGCCCG
+
CCCFFFBBHHGHHEHIJJJJIIIJIIJJGG:EGGHGIJJFHHIIIIGG@GHGGDGGGGHGHIIHIGIJHHHHFFFFFFDDDD>@CDDDDDDDDDCCDDDDD
@0OX
CTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTC
+
@@;DDAEFHHHHHGEHGHGC@?FGEHIIDHHH?EHECIHGGIIIIIGG@DHIIGIIIBHDGDHIIEHAEHDFEBA@CACCCCCCCA>@?BC?BCCCCCC>:
@0OY
CTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTAT
+
:=?ABDDBFCBFHDDFAGEHHEGHGAHHBFB?;9?DGH>FE;-.=CCEG<G?.7=>?CCDF>@EC>CA2?;;;;;>AC;>>CAC??<?B<BBC?<>BBCA>
@0OZ
CGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCG
+
@CCDFFFFHGHHHJJJIGHJGHIIJIIIJJJJJJJIJJJJJJJJJHHHFFFFEEEEEEEDDDDDDDDDDDDDDDCDDDDDDDDDDDDDDDDDDEDDDDDDD
@0P0
CCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGT
+
@@<DDDADFFFFFEII3A?E:CFEDEFIFEEDFFIFEFFIIE;F@AFFEECEAEEFCED>@B@BBDCCCCBBB>ABBBB?B@?;?ABBBBB?BBB>:@BB@
@0P1
CAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATAT
+
?<?=4BAB<D<+ACE9DEEEDA?@EEDD@DD@<?DEB;B?8B7BCCEIIEEI)===@=ACDCDA?D;;?AA@?>??=>?AAAA??<8>>><?<?A>>>:AA
@0P2
GTGATTTTGGTCTAGCTACAGTGAAATCTCGATGGAGTGGGTCCCATCAGTTTGAACAGTTGTCTGGATCCATTTTGTGGATGGCACCAGAAGTCATC
+
CCCFFFFFHHFHHJJJJJJJJJJJJIJJIIJIJIJJIFHIJJJIJJJJJJIGGIIJJJIHIIIIIJIIJGIJJJHHH?CDDFFFEDEDDDDDDCDEED
@0P3
CCCCACACCATCCAGCACGCCAGTGTCCCCACTGCATCATGCATCTCCAAACTCAACTCATACACCGAAACCTGACCGGGCCTTCCCAGCTCACCTCCCTC
+
CCCFFFFFHHHGHJJJJJDHJJJHIGJJJJIJJJIJJJJJJJJIIIIIJJIIJJIJJJIJJJJIHHHFFDDEDDDDCDDCDBDDDDDDDDCDDDDDDDDDD
@0P4
CTGTGTTGTCCCAGAAAAATTCGATGGAGACATCAAACAAGAGCCAGGAATGTATCGGGAAGGACCCACATACCAACGGCGAGGATCACTTCAGCTCTGGC
+
::?ABDD?HFBFH@FAGHCHGBEA@D>HICB@?DD<:?FFFGEGGDDGCHGHHDGHGIE<B@=>>BBBBC@;>ACCBBB=;39B>3?A?CC@:ACC:>:A4
@0P5
GTCAGCCAGGAGGGTCCTCCAGGCCTTCCGCCTCAGCCTCCACCACCAGTTGCTCAACTGGTCCCCATTGTGCCCCTGGAAAAAGCTTGGCCAGGGCCAC
+
<@@?DD;BDF?<D<:<<?HGIG>FEGEHIEDD0DBB<9?BB?FF=BF@F8CGDDC@A;CHC=?;BEEC>A@>>;CB;??BCCCBB?::C?>>9<2&28?@
@0P6
GTAAACTAGGCGTGAGCAAGGCGAACCCAAATGAAACTCTGGTGGAGGTGCGTAGCGGTCTTGACGTGATAATCGGCCTTCGGAGTAGGGTAAAGGGGCA
+
00-2@4)<6=)(0(((.)))(((1((0(7(3.)0)3)).)77?;9?;/=()-56'(,,'''7(22'(,,(7388<&&0&+((&()+(+((+((+((+&&&
@0P7
TTGAAAAGGACAATTTGATAACTAAGCAGAATCAATTAATTTTGGAAATTTCAAAGCTAAAAGATTTACAGCAGTCTCTTGTAAATTCAAAGTCAGAAGA
+
BCCFFFFFHHHHHJJJJJJIJJJJJJJJJJGJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJIJHHHHHEHFFFFFFFEDCEEEEDDD
@0P8
GGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACAC
+
@@@DDDDDDFDHHDAG>FAFCHEHIGGGAEHIBFHAHFHGGIIIIBGGHAG?F8C88@;C@FHIICDEEECECCDEE?BCCCCBCCBC@CC>DCACC@C?
@0P9
GCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATG
+
@@@DD?DDHFHHFGHGGIGHIIIGCDDFCEF>GH>FHIGGGIEGH9B3??BGGIA;FGAGECHFC@>CEB?C>CBCCCC>C>C>ACCCCCBB>C??@CC@>
@0PA
CAGAAAGGCAAATCAACAATGACATAAGAAGGGCTTGTCAAGTCGATCCCAATGTCGAAGGAAACAAAAGGTTTCTTTAAAAGGATGAGAAGCTCCCTGC
+
CCCFFFFFHHGHHJJJJJJJJJJJJJJJIJJJJJJIJIJJJJGIJJIJJJJIJJHJJJJIIIJHGHHHFFF@CCEEEEEDDDDDBDDCDDDDDDDDDDDD
@0PB
AGCAGGAGTACCACGACCCAGTGTATGAACACAACACCATGGTTGGCAGTGCGGCCAGCCAAAGCTTTCCCCCTCCTCTGATGATTAAACAGGAACCC
+
@@@DDD=12AFHFHAAF<EGHCE?9?FGGGGGFH;DFBFGGGDDGEHE@CF7@BHBDD?AACCCCCCACCCCBBBBC?@CCDCDDDDCCCC9????BB
@0PC
TTCAAATATTACAGTTAATGAAGATCAGATAAAGTTAATGAATGTGGCAATAAATGAACTGAATATAAAATTGCAAGATACTAACTCTCAAAAGGAAAAAC
+
CCCFFFFFHHHHHJIJJJJJHIIHJJJJJJJJJJHGJJJJIIIJHIIJJJJJJJJJJJJJJJJIJIJJJJJIJJJJIJJJJJJJJHHHHHHFFFFDCEEED
@0PD
TGGTGATTCCACACTGGGGTCTTCCAAAGAAACCCTTCCACCCACATGCCAAGGCAATCTCCTTATCATGGGGACTGAGGATGCCTCCTCCTTGCCTGA
+
?@<1BDDD>ADDF?FGEII@EEHCHGGIGHCHFCCCGHHHDGIIII@GIEHIGIIIGHGEEEGBGE>CEHEB<DCECCAB@9@BCCCA<CCACCCC>@C
@0PE
CAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGAC
+
@@@FDDEFHHHHHJJJJJEIGIHEHIIIEIIGEIGEGGIIIJIEHHIIIJCHEHIII@FHHIIJJJBHIGCHHA<DBCBBDBDDDCDD>CCDDDCDCDDD
@0PF
AAGAAATACAGGAAAAGGAGACAATCATTGAAGAATTAAACACAAAAATAATAGAAGAAGAAAAGAAAACTCTTGAGCTAAAGGATAAATTAACAACTGCT
+
@<?DDDD>B?D+AAGED;;EG?3C9AEHF@FAFECFFG@E3DAGB;DFFCFDBBE<=FF@CFID=EFIEEE:AECBBDBDDBCC@AABA>>A;>BBBBBBA
@0PG
AGCAGAAAAAAAAGAGAAAAACGTCAAGCAGTAAACATGATGTGTCAGCACACCATGATTTGAATATTGATCAATCACAGTGTAACGAAATGTACATAAAT
+
@CCFFDFFDFDDABBEEHGE@F@8DD@DHCHBBFCHCCCFHE=C=CE=D@E>EH=??@DDFDBCCAAC@>6;>C>C;A(5,:5;;C8?B>?AB>CCCCCC:
@0PH
CCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHHHHFFFFFEEEEDEEDDDDDDBDDDDDDDDDDDDDDDDDDDD
@0PI
CTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGC
+
:?@=1B:DBD8DF?FEA>FCC@GE?EECECFFEEFE>BFB;@G>9BF</?FCBF)==F@AFFD=ACA(=B);7?3>;>@;;>@5>(,,99::A>(((3+(
@0PJ
GCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACC
+
?@@D?DBDFHHHHGB@@F@<CF@FCAHD@EC???@GCHIIBEHD?DCHGGBDFHIGGIDCGII;;=@CEHBEBC@CDECCCCCBCCCBC>C@?A?BC>:<
@0PK
GAGGCTTCCAGCCTGAGAGCACTCCCAGTTTGGATGCTGGACTTGCAGAGCTGGCTCCTCTGCAAGGACAAGGGTTAGAAAAGCAAGTCCTGGGATTGC
+
@<@?DDABFHDHHGGHD?FHIICH>GGGF@GGEHEGGIIFGIIGGHIIIDGGHBCFHIDHHEHCGHDEHCHBDE@A=ACCCCA9?CC>CCCCCBBCACC
@0PL
GAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCAC
+
@@@DFDFDHGFDHFHIJJJGIIJIJIJJJJIIJIJJJIIIIIJJIIJJJJJHFHGHFFFFFEECEBBDDBDDDDDDDDDDCDDEDDCDDDDBDDDDDDDDD
@0PM
GGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGAT
+
B@?DFDFFHHHHHJJJIJJIJJIJJJJJJJJJJJJJJJJJJIJJHIJJJIJJJJJJJHHFFDEEDDDDDDDDDDDEDDDDDDDDDDDDDDDDDDDDDDDDD
@0PN
CAGCAGTCTCTTGTAAATTCAAAGTCAGAAGAAATGACTCTTCAAATCAATGAACTTCAAAAAGAAATTGAAATACTCAGACAAGAAGAAAAAGAAAAGGG
+
@C@=DDDDHDDDF?CGBGHEHHEAAHCFHFDEGHCHIII@GE@GFHGIIHGECFGEBHFIHHDAHGIGIGDHHCGHEDAHC=CHGFD>DCEE>;=BCCC@@
@0PO
CGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJHIJIJJJJJJJJJIJJJJJJJJJHHHHFFFFFEEDEEDDDDDDDDDDDD@BDDDDDDDDD@CDDD
@0PP
CAAAGTCCACAAATTCGAGCATCACCTTCTCCCCAGCCCTCTTCACAACCTCTCCAAATACACAGACAAACTCCAGAAAGCAAGAATGCTACTCCCACCA
+
@@?DBDDDDDFHFIIIGHIIHIIIIGGIGGIIIICGIIDCDHGIIICCHHHGEIIIIIGFHCGIAAEEHHFDEFFFEECCCCDC?CDCDDDDDDDDDDD@
@0PQ
GCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGG
+
CCCFFFFFHGHHHJJJJJJJJJJIJJJJJJJJJJJJJJJJJIJJJIIIIJJJJJJJJJHHHHHHFFFFFEDDDDBDDDDDDDDDDDDDDDDDDDDDDDDDD
@0PR
CTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTT
+
@@CDFEDDDHHHHIEB=2AEEDFEGGEGHHIIIIIHIIIGIIIIHEHIIEHIGIIIIIIIIGGGIIEHGEEFFCBCCAEEEDACCCCCCCBBCB@9>5>CD
@0PS
CCAGGAAGTTCTGGAGTTTGTCACCAGTGGAGGCCGGATGGACCCACCCAAGAACTGCCCTGGGCCTGTATACCGGATAATGACTCAGTGCTGGCAACATC
+
@@@DD;AD=D:C<CA@EDAICBACHII4BBBGDEF?D@:@EFFFI2<F@@FE@@DFFFFEDBB?B@5?5;A@@>;B:@@B@;:A(:3:+:@4:>@<:<??B
@0PT
GGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCC
+
@CCFFFFFHHHHHJJJJJJJJJJJJJJJIJIJJJJJJJJJIIJJJJIJJIIJJJHHHHFFFFFFEEEEEEDDCCDDDDCCDCDDDDDD9@DDDDDDDBDDD
@0PU
CCAGAAAGCAAGAATGCTACTCCCACCAAAAGCATAAAACGACCATCACCAGCTGAAAAGTCACATAATTCTTGGGAAAATTCAGATGATAGCCGTAATA
+
CCCFFFFFGHHHHJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJIJJJJJJJJJDHHHHHHFFFFFFFEDDEDDDDDDDDDDDEECDCDBDDDE
@0PV
CCGTGGAAGGGGGACACGTGAATATGGCATTCTCTCAGTCCAACCCTCCTTCGGAGTTGCACAAGGTCCACGGATCCAGAAACAAGCCCACCAGCTTGTGG
+
@@@DBDFFFDF:@EFHIG?DFDFGIIGIIIGGGDECEHFHIIIIIIGHGHGGIHE??CDE@CEBEB;@AACBBC;;<A>CC:(9?9<BBBCC@BCCC?ACB
@0PW
CAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATAT
+
@@@D?DD?DDDDHGEHIAFEAGFH?;CFGDC@GHICFEHFIIII;DHFHEGEEH@G<=@FHIA@ACA=@;>;;CCCC@CCCBBC?@CCCCCCCC@CACC
@0PX
TGCCTGTACAATGTCAGTGCCTATGATCAGAAGCCACAAGTGGGAATGAGGCCCTCCAACCCCCCCACACCATCCAGCACGCCAGTGTCCCCACTGCATC
+
@;<DDD?DFA?FD:?FFA:?F@?FCHHFHIFEFIEIFEFF:CD9FEGIIFD=BFFF6=FBFEEEFB<>BB?<ABBB:A<<)08>@4>4@AA<?5?A:>:@
@0PY
GCAACTCCAGCTCCCTGGACCACCCGGATGAGCGGGCCCTCACCATGGGCGACCTCATCTCATTTGCCTGGCAGATCTCACAGGGGATGCAGTATCTGGCC
+
CCCFFFFFHDHGHJIJIJIJ@HIIJJBHIIIGIGIGHIII=CCHFFFFFCCDDDDDCC>AC>ADDEDDCDDDDBBCCCCC>>CBB>@BBDCCCDDC@CDDD
@0PZ
TCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATG
+
;=?DDDDDDAFFDG@EGGGCH9D?FHIIIIG>FGG4BDHH@EEHGHEHAHH7AEHHHEEECEE@@AC?ACCCCCACC>>:@CC@B@BBBBA<A@AABCCCC
@0Q0
AGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGC
+
@B?DFFFFGHHHGJJIJHIIIIJJGJIJJGIIJJFEHIJJJJJJJJJJDHIIIJJJIJJJIGHHHHFFBECDEEEEDDEDDDDDDDDCDDDDBDDCDDDD
@0Q1
GGCCGGATGGACCCACCCAAGAACTGCCCTGGGCCTGTATACCGGATAATGACTCAGTGCTGGCAACATCAGCCTGAAGACAGGCCCAACTTTGCCATCAT
+
@@@DDAA8??CDFFFADFFBC8DADF9*0:?BFDFFB?FFB<<FFFIAFCCD=7.77?@7@B@;;@;;5>B;A?B??ABBBBB<<@?<BBAAB:4@BA?AB
@0Q2
GGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTT
+
@@CFFFFFHFDHDHGBAEGDGIGIGHIGGICHEGEHIGHIFHBGGGHEHIIGBBFHHGEHHIIIIIEEEEHADDFFFFCC>@DBBBBD=CDDEDDCDDCC
@0Q3
AACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGG
+
CCCFFFFFHHHHHIJJJJHJJJJJJJJJJIJJIJJIIIHHGIIJGIIBFGHIGIICHJGJIHHHHGFFDFDBEDCDDBDBDDDDDEDDDDDDDDDDDDDDD
@0Q4
GCAAGAACAAGCCAAATCACCGCAGCGTGGGGAGGAGAAATAAGAACAGTTACAAGCAAACGAACTAGAAACAGCAAACAAAGGCATGTGTGTATGGTTGG
+
(((:8).4)))((.)6)))3)((((((100(-(-'((..)))))..6.)..).9).(6(((',69(((((,(,((+++((+((((((+(++(+((+(+++&
@0Q5
CGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCG
+
CCCFFFDFHHHHHJIHIFHJHHHIIIJJJIIGGJJJIIIJHIJJIHHHFFFFEEFEEEEDDDCDCDDDDDDDDDDDCDBDDDDDDBDDDDCDDEDDDDDDB
@0Q6
CCCTGGCCCGGCTGGAGCCCACTATGACCCTGGAGGAGGGACTGCCATTGGCTGAGCAGGAGCGGGAGCAAACCAGCAACTTTGACCGGGTGATCTTTTAT
+
>71A=A;7<0077))2211@5:11?10:A5A>=)95(/4'';(.=7A)).>.7((.))((,((,32-&59(8<8(((83((83((53-0&))(+((53338
@0Q7
CTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTAC
+
???DD;D:+AA?A,A?E?CCF@B<A?F@<A;E@D)?D<DEEI@BA;CDDDIICDC;=C@DA37;?AA6@;>A;>5>BA>>A>:<<<?>:>>A><<(80<AA
@0Q8
CCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAG
+
C@CFFDFB>FDHGIIJIFGHGIJJIJJIJIHIGIGBHHIIIIIIIGJJIFHDG@HIIIJJJJJJGEHHHHFDCEDDC>AA>?BBBBDDDCCDDACEDED
@0Q9
GGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTT
+
?@;BBB=A?ACDDAAGGFFFF3C<A<FHE?CGC@GG@@DC?DFCC2DDABFAFB0FFE2@@EAEFFFEED;89<?BBBBBBB@B?B>>A@@BAB@A>&8?
@0QA
CTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGC
+
CCCFFFFFHHHHHJJJJJJJJJJJJGIGIGIIIIGIGIIGIGIGIJIIIGGIIJIJIIGIIEG@GHHHHHFCEEDFFDEBEECACDCCCDDDDDDDDDDBB
@0QB
GGACGTTAAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGC
+
???DD1D+ADBDDIIIEEDDEICEEIIIIIIEIIBADDIDADCEDIIADDDDCDDDDDDAAAAAA???AAAAAA???>>?>??????AABAADAAAAAA?>
@0QC
CTCAACCAAGTGAAAATGATAAACTTCAGAAAGAACTCAATGTACTTAAATCAGAACAGAATGATTTAAGGCTACAGATGGAAGCCCAACGCATTTGCCTC
+
CCCFFFFFHHFFHJJJJEIIJFHIIJIIJIJIIBGHIJJGJI?GHIJJBHHGIJGGJJIIJIIIIJJJIIIJDEIIJIIHHHHHEFFEDDCBBBDDDDDDD
@0QD
CTAGGATATGGACAGAGGAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTC
+
=+:?<=A>@>=+7?<A;+<ABBB<@@>>7+<?B<@?;11?A??=AB58(0>BBA;AA>B>8=(6.>>>3>AA@@@A@>;>;>;;==;;=;=?=?>=?988?
@0QE
CAGAAACATTGGAAATGGGTGAGGTTGTTGAAAAGGATACAACAGAACTCATGGAAAAACTTGAGGTAACCAAGCGAGAGAAATTAGAGCTGTCACAG
+
CCCFFFFFHHHHHJJJJJJGIIJJIIJJJJJJJJJJIJIJJJJJJIJJJJJJJJJJJJJJJJJGIJCHHHHHHFFFDCBDDDDDDDDDDDDDDDDDDD
@0QF
TAACTCTCAAAAGGAAAAACTCAAGGAAGAACTAGGACTAATTTTAGAAGAAAAGTGTGCTCTACAGAGACAGCTTGAAGACCTTGTTGAAGAATTGAGCT
+
CCCFFFFFHHHGHJJJJJJJJJJJJJJJIJJJJIIJJJJJGIJJJJJJJJJIJIJEHGHIIIIJIGIJJIIIHHHHHFFFFFEEDEEEDDDDDDDDDDDDD
@0QG
TGAAGTTGTTTTGGCTGTGGAGTTTCACCCAACAGATGCAAATACCATAATTACATGCGGTAAATCTCATATTTTCTTCTGGACCTGGAGCGGCAATTCAC
+
@@;DDADDCDB>DGHHIF>G?B<C?AF@GG@EEEDG>??DDGBGBEGGGIEDBGBFGHHIAGIGGEAHEHEECEEE@DDD>>C@>CC@;=CBB?9<CC@C:
@0QH
CTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTAT
+
CCCFFFFFHGHHHJJIJJJJJJIIIIJJJIIJJJJJJJIJJFHIJIIJJIJH=CHHHFFFFFFEEDEDDDDDDDDDDDEDDDDDDDDDDDDDDDDDDDDDD
@0QI
CAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJIJJJJJJJJHHHHFFFFEEEEEEEDEEDEDDDDDDDDDDDDDDDDDD
@0QJ
CCTGATGTGAACCTTATTGGGGAGCATTCTGATGCAGCAGAGCTTGGAAGGATGCTTCAGCTCATCTTAGGCTGTGCTGTGAACTGTGAACAGAAGCA
+
CCCFFFFFHHHHGJJIJJIJJJJJIJJJJJJJJJJJJJJJIJIJJIJJJJJJIJJJJIJJIIJJJJJJHHHHHFFFFFFCEEEEDDACDEDDDDDDDD
@0QK
CGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTAT
+
CCCFFFFFHHHGHJJJJIJJJJJJHJIJJJJJJJIJJJJJJJJJJJJJJJJJJJJEFFFFFFDCCDDDDBDDDDDDDCDCDDDDD@CC>ACDDDCDDCDDD
@0QL
CACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGG
+
@@@FFDFFHFHHHIIIJIJIIJIGJJIJEGFHGJIAGGGIGGCCGHIHIJIJIGIIFHGGHFFFDEDEEEEEDDDDBDBABBDCDDBCCCCCCCDDCDABD
@0QM
CAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGC
+
@@??BDDDFHHFDHIGDFDHCHJIDGHFGDDC=GIJBB09?BBF@FICBBFHDHHHHJGGEACGDEHH3AHBED?ACDDDBDBBDDCC@>CCACAC@CCCD
@0QN
GTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGC
+
@@@FFFFFGBBHHIHIIJJJGJJJIAHGIJJJFIJIIJIJJJIJEGIIJJJIIIGCEHIJJHGEHHFFFFDEAECECCDDDCDEDDCCDB?B>CDDDDDDD
@0QO
CACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCC
+
CCCFFFFFGFHHHJJJBHIJJJJJJJJJGEHGIJIJEGIIIJIJJJIGIJJJIJJJJIIJJJJHHGHGHHGHHHFFFFFEEDCEDDCDDBDDDBDDDDDB
@0QP
CCATCATGCACCCTCTGATCCTGAACCCCCGGCACTCCGTGGATTTCAAACAGTCCAGGCTCTCCGAGGACGGGCTGCATAGGGAAGGGAAGCCCATCAAC
+
C@@FFFFFFHHGHJIJJGGGHIJJIIJGIEHIIIJIIJIGHHCFHJJJGJGGH?AEHFFFFFCEEDBDBDDDDDDBBBCADDDDCDDDDDDDDDD@DCCDD
@0QQ
CAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTT
+
@@@FFFDDHGHHHIJJJDDHGGHIGIIJIGHJJJEHIIIIIIGGIIJJIGIIJIJDIIIJIJJHFHHGHFFFEFECE@CCEDDDEDDCCDDCDCDDBDDD
@0QR
GACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTG
+
CCCFFFFFHGHGGEIJJJJJIJJJJIIFHGJJJGIJIIJHIIJJJIIJGJJBHIJJJIJJJFFFDDDEDDDDDDDDDDCDDDDDDDDD9@CCDDDDDDD>A
@0QS
GTCACGGGAGCCCTCCCTGAAGAATTCCAACCCCGACGAGATTGAAATCGACTTTGAGACCCTGAAGCCGTCCACACTGCGTGAGCTGGAGCGCTATGTC
+
@@@DDFFFHGHHGIIIGGGGHDHGHIGACEEBBHIGHHBEBEGDHHHDF=B>DCECCCB>BBCCCCC@BBBBBBCCB<@CB>>BBCCCCB89><BB9C:B
@0QT
GGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGATACAACCAGCCCAGCCTAGGATATGGACAGAGCAACTACAGTTATCCCCAGGT
+
;<<:<>46).3>.88).216:@5=>@;119:))2))=9)=<>?9?8/''<::?>?97(=;;?;9369=>(((77:<<(52(3(8;5;(+85:<=<<<7286
@0QU
GAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACT
+
@@@FFFFFGFHBHIJJGGGJJIGIIIGIIGIGGHJJJEHIIJJJGJJJGJJIDGIIJ@GEEHEHHHHGFFDFFE>CCCBCCAADDBDDBDB@BCDDDDDD
@0QV
TCACTATAAACAGCAGATAGATGGTTTACAGAATGAAATGAGTCAAAAGATAGAAACCATGCAGTTTGAAAAGGACAATTTGATAACTAAGCAGAATCAAT
+
:?@DBDDDHAFDBECAF9A@I@FA3A?FGE?<??@@FGH<?BGHIIGD;D9B9B?D@FCB=BFC8BCDFGAF=D@CEEAECB;;@BD;AA((66?C@ACCA
@0QW
AGGAAACCTCAAGCTGAGAAAGTTGATGTGATTGCCGGCTCCTCCAAGATGAAGGGCTTCTCGTCCTCAGAGTCGGAGAGCTCCAGTGAGTCCAGCTCCTC
+
CC@FFFFFFDFBD<AFCEHGIDDHG+AHEHGFHIGGAGHGHGIHDFICC<CHIC@@AGHIGE=(;CBDCCEEACCDB?=B@CCC>A>>@C>A+:@9C:CDC
@0QX
CAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGAC
+
8??BDDDD<?DDDGHE<ACBEE??F;BGGEF<?<?FGGHDHIIHGGD??A?D?FHBC88==FCFEA>AC=;=CABBDB>?;;@CA:@CCACCCCCACC:@
@0QY
CTATGACAAGCAGGGGTGCTGAAGGATCAGTTTCTAAAGTAAATAAAAGTTTTGGTGAAGAATCAAAAATAATGGTGGAAGATAAAGTTTCTTTTGAAAAT
+
@@@FFDDFFHHFCDGHCCEHGGGHIHGHIHFHIGBGIIGIJJJJJIG9D?DHIJI@@HGGJGHCEGEHHGHFFFF;@ACC>ACCC>A>>CACCDDC?CD@C
@0QZ
GATTAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCC
+
CCCFFFFFHHHHGJJJJJJJJJIJJJJJJJIJJJJJJJJIJJJIJJJIIJJJJJJJJJJJJHEHHHHHFFF@DEEEEDECDDDDDDDDDDDDBBDDDBDDD
@0R0
GCTCATCCCAGCAGAACAGAAGGCTGTATGTTTGAAAAGGGCCCCAGGCAGTTTTATGATGACACCTGTGTTGTCCCAGAAAAATTCGATGGAGACATCA
+
<<@DDD4A=CDF;E3CAEBGCCA@EF?FGFGFF@F>FGBBDDFEFF@=FEFFF@FG;=@@@CEEEFFF3?7;BBB>@@6?BB?B@;A?B:>=>???BB@A
@0R1
CACATGGCACAGATGGAGGAAATGAAAACACGGCATAAGGGAGAAATGGAGAATGCTTTAAGGTCATATTCAAATATTACAGTTAATGAAGATCAGATAA
+
@@@DDDDDFFFH?GGI9F;A<?FHHCEGHHIGIIGDGIIEH9@DHIGGGIGIEG@;C@;DAAA.=A>C@B;?DDACDCB@CC>@AACACCCCCCCCCCCC
@0R2
CCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGT
+
CCCFFFFFHHHGHJJGGGHIIIJJJJJJJIJGIJIGIIIIGIIEIIIHIDFGHHGGHGIJIGIEHHGFEBCEDCBDECDDDDFD=BDDDBDBDDDDD@BC
@0R3
TGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTAT
+
@@@FFFFFFHHGFIGFHGGEFHFHGGEHIIIGIGGIIIGJFGIIJJJIIGGHIIGIHHHGFBDEFDDDEECDBCDDDCCCD?BBDBDBCCDDEDEDDDDD
@0R4
GCAGGAGGACCACGACCCAGTGTATGAACACAACACCATGGTTGGCAGTGCGGCCAGCCAAAGCTTTCCCCCTCCTCTGATGATTAAACAGGAACCCAG
+
==>;<++)<=C87<7)12:?BA@1?BB?BBA?:=0==5==A*/;'=)-)8>44=/9;<1;==9((:;?:9====<=9:??8;38:?:???<<=7(29;;
@0R5
CCGCCCACAGGTCTGCCAGCTTGGGTAGGCGGGCGGAGGATACAGTGTCGAAAAGATGCGAGAGGGGCATGATCATAGGGATGAGGGCTGGGCTCGAGGG
+
0--2((((2((.29<@18)(.))(.()-9.(('',''',(2(((+(((()22()++8(3&+&07(&&&)((+(++6(++++(((((()8&)2/(+)&&&&
@0R6
CCTGGCTAATGCCTGCTATGCAATACATACTCTTCCAACCCAAGAGGAGATTGAAAATCTTCCTGCCTTCCCTCGGGAAAAACTGACTCTGCGTCTCTTGC
+
:+12<+?@><7+<AC9?<?<@<ABB>ABCBA@C>=<A@;:8A=:;3=>AB>?<?BB<>>ABBAA)3;>A3=A>AA@</=<>=6;;;????:('329;;88(
@0R7
CAAGAAGCTGAATTAGAGAGGCTGAGAACACAGCTTCTATTTAGTCACGAAGAAGAGCTTTCCAAACTGAAGGAAGATTTAGAAATTGAACATCGAATAA
+
CCCFFFFFHHHHHJJJIJHIJIJIJJJJIJJJIJJJJJJFIJIJHGIGIGJJJJIJJIJJJIJJJJIJHHHHHFFFFFEEDEEEDDDDDDCDDDDDDDDD
@0R8
CTCAGACTGCCCTCAATTCGACTGCCCCGGGCACTCCCTGTGGAGGCCTTGAGGGTCCTGCACCTCCATTTGTGACAGCATCTAATGTGAAGACCATTCTG
+
@@<DDDDABFHHDHEHIDCEEH?DHGHIIB?FFH?BDHGGBFG@C@FHI@EB;?EEDEDED@ACCBBCCDDC;?CCCCBCCC@5>A@CCCDCCCC?CCDED
@0R9
ATGAACTATGATAAACTTAGCCGTTCACTCCGCTATTACTATGAGAAAGGAATTATGCAAAAGGTGGCTGGAGAGAGATATGTCTACAAGTTTGTGTGTG
+
@@@DDDDFGHFHGJJIIIJJIJJJJIIIIHJIIIIIJJIIIJJIGGIGGHIIIGIGHGIIIJJG7CHGCEHHFBDFDDCEDDFEDCCDDDACDDBDCBBD
@0RA
AGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCC
+
CC@FFFFDHHHFHIJIIJIJJJJJJJJHGIJGHGIIJJJJIJJJJGJJJJDIGHFHGHFEFEFECEEEEEDDDEDCDDDDDDDDCCDDDDDDDDDDDCCDD
@0RB
GCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGT
+
CCCFFFFFHHHGGGJJJJJIJJJIJJIIJJIJJJJJJJJJJIGIJJGGIJJJIIJGHIJJJJJHCEHHHFFFDDCEBEDDDDDDDDDDDDDDDDDDDDDDD
@0RC
CCATGCTCGATGCTACAGCCAGGCTCCAAGTCAATATGGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGGCCACCCCAGTAGCATGG
+
7;;((:>)=(9)8;.=9>1(.(((:(18).9)3):.=))0.)33(0::7<95((())83//=;/6;((.:.96(:790''',8(8:9-2:66:=/(8:(36
@0RD
AAAAACATCACCCTCATTCGGGGCCGGGGCCATGGCGCCTTTGGGGAGGTGTATGAAGGCCAGGTGTCCGGAATGCCCAACGACCCAAGCCCCCTGCAAGT
+
;3(33>7)8<>@?<<<>=;?958(<((73;35:);?;6=?88;;8595/((,;:=3((73/2(+8:+4/8689<5(+66(868&5:/+(266:5&8(8:;+
@0RE
AGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGAC
+
@@@DFFFFHHHHDHIJIJJJJJGEHIIIIJDDGGIJJJJGHIIIJJJIJJJJJIIJIJJEIJJIJJICHHHCEFEEFEEEDEDDCEEDCCDDCDDBBDDB@
@0RF
AGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACA
+
:?:A:A?;FDAFF<B3EEG>GFAC<EFFII>F@??@>DBFFIG?4D?<;DF8<B)8BACFFGIFII@AC:CEED@>?@>ABBB=9;<?<BABB@AA>BA:
@0RG
CACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGAT
+
@<@B?DDDFFFADIHIH6@:EEDG9?FGE@F=DDGBFBD4DC>FE8?CHIGB;FHI@E@EGEAEHED?B6>A>CC?C???ACD@CCCC<?5>B@BB(((>>
@0RH
CAGAGATTTTGCATATGACTCAGAAGTGCCTAGCTGCCACTCCATTTATATGAGGCAAGAAGGCTTCCTGGCTCATCCCAGCAGAACAGAAGGCTGTATGT
+
C@CFDEFDHHHHHIJIGIIIJGFEHJEHHHIJIJJGHHIJDHGHIIIGGJJJIFGGHIGEHGHGGIIJIGIEHGGHHHHHFFFFFE@ECDDCBBCBBDDDB
@0RI
CACGACCCAGTGAATGAACACAACACCATGGTTGGCAGTGCGGCCAGCCAAAGCTTTCCCCCTCCTCTGATGATTAAACAGGAACCCAGAGATTTTGCAT
+
7+==+)<<A2<A+?ACBA+AAAACB?<A4AA:4?63>;A<4::AAA<;;=77>@>>@>>;>=96;=>(59=>=999;?9==<8<=<==<==<???????:
@0RJ
AGAGGACAAGTGCAAGCCTATGTCCTATGAGGAGAAGCGGCAGCTCAGCTTGGACATCAACAAGCTCCCCGGCGAGAAGCTGGGCCGCGTGGTGCACATC
+
??<BBBD?FFBFAFHHGHGIIIFFFHGEHIIGCHCGGGHIIEEHEHHIGDGDDHAHGGHHEHHFFFFECCCCBCBBBBCCCCCCBBBBC>BBBBCCCCCC
@0RK
CAAAAATTCACCGCAGTGCATCAGAACCCTCCTTGAATCGGGCTGGTTTCCAAACAGAGGATTTTAGTCTATATGCTTGTGCTTCTCCAAAAACACCCATC
+
@@@DDDBDDDFD?@GGHBDED?GC@?FCH;?DHE<4:?DGDADBAB==CC@4@GG2@AEC?3;@B:7.(;CD@CCCCDAACC>AC@CCCCCBBBBBB><C?
@0RL
ACTCTCTTTAGCTTTTCTTGTCAGACAGCTTGCCCAGTTTCGACAAAGAAAAGCTCAGTCGGATGGGCAGAGTCCTTCCAAGAAGCAGAAAAAAAAGAGA
+
C@@FFFFFHDHHHJJIJJJJIIJJGCHIJIFGIJGGGIIJJJJJIJJIIJJJIIIJJIIGAAHIGGFEFF?C>CEEEDDDDDDDDDDDDDDDDDDDDBDD
@0RM
CCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTAT
+
@CCFFFFFGHHHHJJJJJIJJJJJIJJJJJJJJJFHIIJJJJJJJJJJJJJHHHFFFFFEEDEEDDDEDDDDDDDDDDDDDBDDDDEDDDDDDDDDDDDDD
@0RN
GATGGAGGAAATGAAAACACGGCATAAGGGAGAAATGGAGAATGCTTTAAGGTCATATTCAAATATTACAGTTAATGAAGATCAGATAAAGTTAATGAATG
+
C@CFFFFFHHHHHJJJJJIJJJJJJIHIJJHIFHIIJJIJIJJJIJJJJJIIFHJJJJJJJJJJJHHHHGHHDFFFFDDEEEEDEDDDDDDCDDEEDDDED
@0RO
GTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGC
+
BB@FFFFFHHHHHJGIJJJJJJJJJJJJJJJJJJJIJIJJJJJIJJJJJJJJHHHFFFFEEEEEEDDDDDEDDDDDDDDDDDDDDDDDDEDDDDDDDDDDD
@0RP
ATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGAT
+
18?DD?3=C4<DDE>AE<C3:;:EEC3<3<;1?EDAFEDBBDEDDEEA>EDII>A176A).=AAADDD@@@@>AAAA?6'38>35<>A<98><>A::>AAA
@0RQ
CAAATTCTCACCAGTCCGTCTCCTTCAAAATCCATTCCAATTCCACAGCCCTTCCGACCAGCAGATGAAGATCATCGAAATCAATTTGGGCAACGAGACCG
+
@@<DDDDDFFFBCGCFB;:AF?HH4+<CEH?BFGIIBF<F>FEGEEIIFEFIAF?676-5CCAC;77CEF).;B;;;;@C;;AABA;;>=@@<?;B@59?9
@0RR
AAATAATAGAAGAAGAAAAGAAAACTCTTGAGCTAAAGGATAAATTAACAACTGCTGATAAATTACTAGGAGATTTACAAGAACAGATTGGGCAAAAGAAC
+
?@@D;DD><F>BFGDG@CF>EEC>G@B<+<4:?E><<*:3F<:*0*:D9?F)0*?*8?*/)))/)=C))7=C()7C3=A))..7?@>((((.5=@==38<<
@0RS
ATCACTGCCCAGCGTCCTCCGAGTCCCACCCGAAGCCATCCAGCCCCCGGCAGGAGAGCACACGCGTGATCCAGCTGATGCTCAGCCCCATCATGCACCCT
+
???DADDB;;D=C)C?E;C21)1:C<C@DDD06?DDD)=)8<=@;@AD:'59835828(:5<?-5;5>>3:AA(9(4((+:AAA3>???<>?3>AAAAA?<
@0RT
CGACAGGGGTAACCTGGGGCTGGAGGGAAGCTGTACTGTCCCACCTAACGTTGCAACTGGGAGACTTCCGGGGGCCTCACTGCTCCTAGAGCCCTCTTCGC
+
;?;ADDD?F@@AAFFEE?@?FFEEB:?GBD@?B9?D<?FFHIIG8@@7C@=C=E?EA?@D=>;'5;A@CBBBBBBB8A:?>>@@A@9@:CCC?BCB<CCA9
@0RU
GGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGC
+
;??;D?DD<FFHCFHII9@EEHGE@B;D@BFBEGHABCGHBF;F<=CDCFFHHGBGHEBBBD?AAC??CAACB>(5>C>>C<?BB?@BB8?BB?:>>4><<
@0RV
TGATGATTGGGAGATTCCTGATGGGCAGATTACAGTGGGACAAAGAATTGGATCTGGATCATTTGGAACAGTCTACAAGGGAAAGTGGCATGGTGATGTGG
+
<@?DDDADFDFFHGAHGG>H4CEDFGHGCHB>*:?9CAH?D?DDEIGGHD?9?8=CDD<A>FEG=ECGCG;?>CA3=CEBBCCC;;AC?=>;?::5>5(,:
@0RW
GCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGC
+
@@@FFFDACFFHGJJGIJIIJJHGIGIIJHIJJFIGGIIIGIIDDGIIIJJJIJIJIJJJJEEHACHEDDCFEECDCCDDDC@CDDDEDEDDCDCDDBCCC
@0RX
TTCACTTCTAAAACAGTCACGTGGAGCTTGGGTGTGCTGCTATGGGAAATCTTTTCTCTTGGATATATGCCATACCCCAGCAAAAGCAACTCGGAAGTTTC
+
:=;;+,+<,<A<+222227+)33;++2+?*:=)00:**:=>*90=A;BB>?))7=7)/=).))7).7)7)=37=7;7=@(;(6(,5=;(5((,(',)+((+
@0RY
TTTTAACTCTTGGTCATCAGCCTTATCCAGCTCATTCCAACCTTGATGTGTTAAACTATGTGCAAACAGGAGGGAGACTGGAGCCACCAAGAAATTGTCCT
+
@@@DFFFDHDFHBGGGIJJFEGHGD?<CDGHJIHIJIGDFI8FHGDB@GGIIGGIIIIIJB@DH@FD=C@>FGG8A8?CBDCCE=@CBDDDDCD:@CAD@C
@0RZ
CGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCG
+
CCCFFFFFGHHHHJJJIFGIHHIIJJJHIGIIIJJJJGIIHGIJJHHHFFFFEEEEEEEDDDEDDDDDDDDDDDD@BDDDDDDDDDDDDDACCEDDDDDDB
@0S0
CCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTAT
+
CCCFFFFFHGHFHJIJJIIGGIIJJFGEHJJJJJGHGJIJIJIIIIJIIIFHHHFFFFFEEEEEDDCDDCDCDDDDDDDDDDDDDDDDDDDDDDDDDDDDD
@0S1
GGAGTTTGTCACCAGTGGAGGCCGGATGGACCCACCCCAGAACTGCCCTGGGCCTGTATACCGGATAATGACTCAGTGCGGGCAACATCAGCCTGAAGAC
+
:;?>;22:CDC:<:2<2+CFF:A1@ED6;?0?BADDD((9=B=4)).@A2@=2?55;A>B@),'''35;(::A::3,:>'59>38<(3444>991((44(
@0S2
CCCTGCCTCATTACCTGGCTCACTAACTAACGTGAAAGCCTTACAGAAATCTCCAGGACCTCAGCGAGAAAGGAAGTCATCTTCATCCTCAGAAGACAGG
+
CCCFFFFFHHHHHIJJJIIIIIJIJJJFJJIJGGGHHIGJIIIIIJGIJJJJJJJIJGHIJIJJGJGHHFEFFFEEEEEEDDDEEEEDDDDDDDDDDDDD
@0S3
GTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGC
+
@@CFDFFFFDDFHJIGIGGGIEIIGIGGEIIFIJIHIIJJJJJFIGHJBGII?HHHHE;?@DFCEEEEC@CCCDDC<<@:>C>CDB??9ACCDDBDDDD
@0S4
ATGAAATGGAACAAGATAAAAAAAGTAGAAAACTCAAATAAAGAAGAAATACAGGAAAAGGAGACAATCATTGAAGAATTAAACACAAAAATAATAGA
+
@CCFFFFFHHHHHJIJIJIIJJIIIFGHIIJJJIJIJJJJJJJJJIIIJJIIIIJDIJJIIGFEHHFFFFEFECEECEDDDDCDDBDDDDDDDDEEDC
@0S5
CTGAGTACAAGCTGAGCAAGCTCCGCACCTCGACCATCATGACCGACTACAACCCCAACTACTGCTTTGCTGGCAAGACCTCCTCCATCAGTGACCTGA
+
?;?DDABAFHBFDGGHIIAGH<EEFEBHGGFE?DFHGIEGEGH<FGGIBEA>>CBD1=A6;ACCC@CC@CACCBCC8<<<>@?3<CC>AACDC@CCCC?
@0S6
CCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTC
+
+??DADDAAD:;A2A@C>;<CED81?0?BB<:BD>D>@CDCBBD<B;@=CCCDDC6@AA3?>??3;>;:?>>@;;;>=>??=??884:>>4:8<<2(324:
@0S7
GGAGGAAGAAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAACCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCGAACGCAAGGAT
+
1(--(8((()):6).8=)))3(-(:()(-99=>1)))00):>??1=:=1(-.(<).33/=39.6('(,902;0000((5022:5008</&&00&&)088<:
@0S8
ATTGAAAATCTTCCTGCCTTCCCTCGGGAAAAACTGACTCTGCGTCTCTTGCTGGGAAGTGGAGCCTTTGGAGAAGTGTATGAAGGAACAGCAGTGGACAT
+
CCCFFFFFHHGHGIGJIJGGIIJJJGIIHIIJJGIIJGIIGHDGDHGIJJJEGGJIIGHDGHEHHFFFFFFCCC>A5@;@CDCDDDDDDDCD?BCCC@CCD
@0S9
CCACACCTGGGAAAGGACCTAAAGGTGTATATCAAATCAGCAAACAAATCAAAGCTCATGATGGCAGTGTGTTCACACTTTGTCAGATGAGAAATGGGATG
+
@@@DFFFFHHGDFHIJIGIIJFIHJFGCGHGHJIJIGGGIGIJJDGJIJIJIIGGIIIGIDGIJIJJ=C@CEEHHHFFFFFE@@C@CCD>CCCACCDDDCD
@0SA
AGCAATCAGGTGGTCGTACAAACTGCATCAGGAGATATGCAAACATATCAGATCCGAACTACACCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATGAC
+
C@CFFFFFHHFDFEHHIJDIIGIGEIGIGIGFHIJFHIH4DFGGH>GIIIIIGIGGIIIGIJIAGCHEHHFE@@DFEDECAECDCDD@DDCCCDCD>ACDD
@0SB
GCAAGAGAAGTGCATGGTGGGCAGGAGCAAGCCCTAGATAGCCCCAGAGGGATGCACAGGGATGGGAACACTCTGCCATCCCCCAGCAGCTGGGACCTGC
+
@?@FDFFFHHHGGJJIJBFHIFIJIIJCFBHGHGIIJJJEHHGIJJEHJJIHIIAGIHHHH?DDFDEEDBDDDDDCDCDDDBDDDBBDDDCDDDBBDDD?
@0SC
CTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGC
+
;+;:ADD?<F8FB@DEBFCFD;EFGIEBF<CEBFF9DD@FDFBDF?<FC??31;))8C=@;;C;;=A(?>3?);@B;(;3@A;>;@B=9?AB>:<@BA>:
@0SD
CCTGGCTCATCCCAGCAGAACAGAAGGCTGTATGTTTGAAAAGGGCCCCAGGCAGTTTTATGATGACACCTGTGTTGTCCCAGAAAAATTCGATGGAGAC
+
C@CFFFDDDHGFHJJJIGEHGGGGEEEGHIFDFGEGGHHGIJAEHIEHIFHCGHHCGEGEHJGEIHHFEECD;@CECAEECDDBDDDDDDDDCCA@CACD
@0SE
CTTCTCGTCCTCAGAGTCGGAGAGCTCCAGTGAGTCCAGCTCCTCTGACAGCGAAGACTCCGAAACAGGTTAGGTGACTTGTGTTCTACGTGTCTTACCA
+
CCCDDDDFHFGFFIIGFGGIGIIJGGIIJJGHJIFGHIJGGIIGIIJJJGGEHGIHEEFFEFFDDDDDBCACBD:A>CDDDDDDDDEEDDBDDDCDEDDD
@0SF
CGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCT
+
=<1?1<AABBBA8?<AA+377+<ABAC<CBB?*1?*:=ABB>):00*00=AAAA;B25)>A<ABBA>AAA9>>3<@@@==?;=?>>9;,9955>=;<=7;8
@0SG
CCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGC
+
@CCFFFFFHFHHGIIIIGHGIJJIGEHIIIHGIIJJJIIJIIIJIGGIIGGJIIIIIIJJJJJJJJ@HEHHHEFEDDCDABBBBDDCDDDDDDCDDDD
@0SH
TGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJHHHHHFFFFFBEEEEEDDDDDDDDDDDDDDDDDDDDDDD
@0SI
CCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTTATGGGCAGGAGT
+
@@CFFFFFGHHHHJJIIIJJJEGGIEHIJGHGHJIGGIIIJIJJIIHEGEHFDHGHIIJJJEEEFFFCCCDDDDDDDDDDDDDB59BDDDDCDDDC@BBDC
@0SJ
AAAAAGAAAAGCACAAAAGGAAAGAGGAAGTGGAAGAGAATAAAAAAAGCAAAGCCAAGGAACCTCCTCCTAAAAAGACGAAGAAAAATAATAGCAGCAAC
+
@;?DDDB;FF??HDHEEHGGHEEI@FE9EC1?DFG;?F:?BFCGAFHG8;D=C;C;?EHEEEBCCCC=A>;ACCC>@898=>?<CCCA?AADD@CCAB@C<
@0SK
TTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACC
+
CCCFFFFFHHHHGJJJJJJJJJJJJJIJJJJIJJJJJJJJJJJJJJJJJIJFGIJIJJJJGHHHHHHFFFFFEEEEEEDDDDDDDDDDDDDDDDDDDEDDD
@0SL
ATTTTAGAAGAAAAGTGTGCTCTACAGAGACAGCTTGAAGACCTTGTTGAAGAATTGAGCTTTTCAAGGGAACAGATTCAGAGAGCTAGACAGACAATAGC
+
@CCFFFFDDHHHFJIAFFFHHIIIGJGGIEIJJIJJJEGGFHEIGJIGIJGIIJIGIIIBFHJGIIIJIGGEHGHEHHHCEFDBACCC@CDCCDBDDDDCD
@0SM
GCCTCTACAACCCCACGTCAGAGTGTGGGATTCTGTTACTCTATCCACACTGCAGATTATTGGACTTGGCACTTTTGAGCGTGGAGTAGGATGCCTGGATT
+
===BBDDDD8DDDIIDA2:2@AE111*1CBD@DIEB4DECEAD@D@<B?BCE>=B;8@@CDEII>@ADCDCDDD>AA=?:>3>?1<,:5>53:9+::<1>A
@0SN
GATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCT
+
@@@FDFFFHHHGHHIGIJJJJJJJJJJIJJIIIEGGIJJJJIJJJJIJJJJJJJIIIJJJIJJJJJIJJHHHHFFFFFFEEEEDDDDDDDDDCCDDDECDD
@0SO
TGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTC
+
;?8;B+@BFC>FFIEBEABGHACDFFBHD>@BD?BCDGDAB@BBDBHGGCHGD>AHDFEEGHC=DHIIFCHHEECCBA@@>C@:;>CAC@?@?:>ACCA>4
@0SP
GATAATGTGCACCATAACCCTCCCACCATTGAACTGTTGCACCGCTCCAGGTCACCTATCACGACAAATCACCGGCCTTCTCCTGACCCCGAGCAGCGGCC
+
@@@FFFFDFHGBDGGHIIIGIIICHEGGHIGDGEFHGGGGGIIIIGBEEGI>HGIIIGHIDHHHFBDDFEEEEBB?BDDDDCCCCCDDD@D<BDD?ABDDD
@0SQ
TGGCAGTGCGGCCAGCCAAAGCTTTCCCCCTCCTCTGATGATTAAACAGGAACCCAGAGATTTTGCATATGACTCAGAAGTGCCTAGCTGCCACTCCATTT
+
@@@ADDDDDFAD8<CA=GH>D>CD<FCHGIH@GBCHEIIGIGG@BDHGA26CE;E=?A=B7@DD3@>A>A;;@CCCCCC?C>CC@(9AC(:2:CC?<>CCC
@0SR
TTTAGGCATTCACTATAAACAGCAGATAGATGGTTTACAGAATGAAATGAGTCAAAAGATAGAAACCATGCAGTTTGAAAAGGACAATTTGATAACTAAGC
+
<@@ADFFFHHFHFEIGIIIIIIG@EEGGGGEHIIIGGGGHBFFEIGEHHGHHGHIIHGHIIGHIIIIIIIIGGHGHG@CEEHGFDFFEEEADEDCCCCCC?
@0SS
GAGAAAATGGCGTCCACGGATTACAGTACCTATATCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGAC
+
8??DD8:+++<C?CEEBBD@EDCBD31:*C?DD>*:?D9?)*9?D/*7/;''=.(',.6?3(.(6;3.;55;98;;?(80<<?(+99(+843(+:>::<9<
@0ST
AGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGAC
+
@C@DBDBEFBFFBCGE>FFE@FEEBAHHCEHEAEHHGDHG;FGGHEBFFHEHGIIEGIGHHHGHHE@DCECEFDF:@>@C=AC@CCCCDDD>@C:??A=>@
@0SU
TCTAAACTTACCCTCTCACCAAGGGAGCATCCCCTCAGTCCTCACCATGCCTCAGGAGGTCAGGGCAGCCAGAGAGCATCCCACCTGCTCCCTGCTGGAGC
+
=11?7>@AB=+<??C3A=CB3+<+?7C<=:?7=ABA)???B?7?099ABB>>BB)..5A533A>>(;9=@5>6=(,5;>??=?A=:5;(582382:??999
@0SV
TGAAGAAATAAAACAGTTAATGGGGACAGTCGAAGAACTTCAGAAGAGAAATCATAAAGACAGCCAGTTCGAAACTGATATAGTACAACGAATGGAACA
+
BCBDDDDDHGHHHJJJIJIIHGIIJHIJJJJJIJJIJJJJHGGJJIIJJJIJIIGIJJIIGIJJJJJHHFHHFFFEEECDCEDDEDDDCBDDDDDDDDD
@0SW
GGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGT
+
8:8=A3BDA?<CB?E<+<<<F@E@??B)?GABFFD?>?F@FFICF3BFFCFF@=CC@:A3?=9;?=BC;@A?>@@A@BB><9>BA:(((22+8?<(:(:>B
@0SX
CAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCC
+
@@CDFFFFFHHHGGHJJJIJJJJIGIIIJJJJJJJJJJJIIJGIIIIGBHIIJIIIJIJJJHHDFGFFFFFECEDDDDBDDDDDDDBCDADEDDDDDDDD
@0SY
AGGCAGTTCCGGGGACCGGCGGTGCAGGCCGCACTCGTGCGGCAGGGAGGGAAGGGGGACAGCGTTGGTGACAGACGGGGGATGGTGGTGGTCATGCCAGG
+
+7+?++2<,,<)?))2:)?)84'--))(51',399(((,,8-&)00&(&&&&+++)7&&)(((&(()8(2(+(((()0)&)&)+(+++&2+&+(++33(+8
@0SZ
TCACAACCTCTCCAAATACACAGACAAACTCCAGAAAGCAAGAATGCTACTCCCACCAAAAGCATAAAACGACCATCACCAGCTGAAAAGTCACATAATTG
+
===7?AAA;A7=?=77?AB=+?@++<7+)*1:?BB=AB7?AA=>ABB9A?*0*7>;===.6>(77=7.=)594/35;===>=(55;;=?>,,538(+838(
@0T0
CCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAAC
+
CCCFFFFFHGHHHJHIIJJJJJJJJJJJJIJJJIIIJJJJJJJJJJIIIIIJJJJJJJJJJJJJJHHFFFFFFFEEEEEDEDDDDDDDDDDDCDDDDDDD
@0T1
CTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCC
+
??@7B;BDDFHDAHGGIGCDFFDHFFFGD@HGCGGE3DF?DDGGDC/8=>;FF;@CGEAGGHH=>9@@);@@CECC6@52;9?<?8?B<::4>C>>?@<BB
@0T2
CTGAAGACAGACATGGAACGTCACATCAACGAGGAGGACACAGTGCCTCTTTCTCACTTTGATGAGAGCATGGCCTACATGCCGGAAGGGGGCTGCTGCA
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJIJJIJJJJJJIIJJJJJJHJIJJJJJJIJHHHHHFFFFFDEEEEDDDDDDDDDDDDDDDDDDDDDD
@0T3
AAGCGGCAGCTCAGCTTGGACATCAACAAGCTCCCCGGCGAGAAGCTGGGCCGCGTGGTGCACATCATCCAGTCACGGGAGCCCTCCCTGAAGAATTCCA
+
@@@FFFFFGHFHHEGII@CHGIGGIJEDHGIAHDHGGIEGB6<BCCCECB?ABDDBDB<@CCCCDA@CDCDDDCDDDDDDBD<BCDDDDACCCCDDDCDC
@0T4
CTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAA
+
@@CDFFFFFBHHFGGIJJGIIIIIGJJIEGHIJDDHIIJJGGGIIIIFGIHJJIJJIE=FHIJFFEF@CEEECDDDDDDDDDDDDDDCCEDCCCDCDDDD
@0T5
CCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAG
+
@@@FFDDEFHHGG@FHEHJIJIIJGIEECEEGHIJGGFIDHIDGBFE8DDFFHIEIEHIIJJGIJAGEHGFHFCDFFDCABDB@BDDDDDDDDCDDDDD
@0T6
CACGAGTTCAGCAACAAGAAGATGAAATCACTGTGCTAAAGGCGGCTTTGGCTGATGTTTTGAGGCGTCTTGCAATCTCTGAAGATCATGTGGCCTCAGTG
+
CCCFFFADHHHHHJJJJJJJJJJIJIIJJJJJJGHIIJJJJIJJIJJJIIIIIHEEEEFFFFDDECD=BDBDDDDDCCDEDDDCDDDDDDCCDDDCDCDAC
@0T7
AGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTTATGGGCAGG
+
@@@FFFFFHHHHHJIJIIIJIICHGIJJJIHIIIJIJJJIIJIJJJJJJJJJJJIIGGIJIJGHFFFEDDDDDDDDDCDDDDEDBD(50?CDDDDDDDDD
@0T8
CTTGGACCTTGCGGCGTCCACTCCATCTGACTCCCTGATTTATGACGACGGCCTCTCAGAGGAGGAGACACCGCTGGTGGACTGTAATAATGCCCCCCTCC
+
@@@BBDB32=CFAE>ECF@?DF;?B??DB8?BFBFDFAFFA@F;=@CC=BD?>8?B;>ABB8??=??(2(9@B599@(3<2>>8:>@>BB>A@BBBB@99@
@0T9
TTTGCATATGACTCAGAAGTGCCTAGCTGCCACTCCATTTATATGAGGCAAGAAGGCTTCCTGGCTCATCCCAGCAGAACAGAAGGCTGAATGGTTGAAA
+
;((((.8>?8)))..<).4.;:..39>)8.(:@>53.<?1...1:.6=(-:(=)<((9>)=>>>5;7)63;3;63).....==5(6(=7(73-(-5(,,,
@0TA
CTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATG
+
@@CDD<DDFDHHHE>GB>CGEFHHIFEGEGIGIBB<GE9BFIIG:FFEHEEAAEDEECFC;AACCCECCCCBBCC@@<AB88>CCDCBBCBBCC?CCCCCC
@0TB
GGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATG
+
CCCFFFFFHHHHGJJIIIIHHIGIJJIJJJJJJJJIJJJJJJIIJJGGIIIJJJJHHFFFEDDDDDDDDDDDEDDDDDDBDDDDDDDDDDDDDDDDDDDDD
@0TC
CTCAAGTAAGCTCTTTATTAGATGGAGTTGTGACTATGACAAGCAGGGGTGCTGAAGGATCAGTTTCTAAAGTAAATAAAAGTTTTGGTGAAGAATCAAA
+
@@@DDDBDD??FHADDGG<HECEH@EFAB>9ADH@GGHGIBG9DE;@6<)?CE)=C8@;7)@DCGAHAHHHE7A>@BDDEB@;@;>;;5?CA>C9@C:::
@0TD
CAATAAACAAAACTACGGCAGGAAGGCGTGGAAATCCTACACAGTGCCGCGCAAAATAAACGCCAGGGTGAACGCAGGGAGGAGCACGACGGCGGGGAGA
+
+++<22++++++2+2++<33?=)))11:0)0)*9?90=*9)..88)))'-5',''(-;-(,,'''&(&+((((8;;9&5()0(+(++59&&0)55&&&&&
@0TE
CTGGACAGTTACCTTATTCAAACATCAACAACAGGGACCAGATAATTTTTATGGTGGGACGAGGATACCTGTCTCCAGATCTCAGTAAGGTACGGAGTAAC
+
@@@FFFFFHHHGHJIEIJIIJJJIIJJJJJJGIJJIIJJJIJJIIIIJJJJJIEHIIJJJJIGFF@DEFDCEECEDDDCDDACDDDEDDDA:@BDBD?CCD
@0TF
CTCCAACTAAGGGTCAGCGAGGACACCTGCCCACTGAATGTTCATTCTTATGACCCCCAAGGAGAAGGCAGGGTGGATCCTGATCTGTCCAAGCCTAAAA
+
?@BDDADDDHHFHGGHGEGGHGIGIJIJJIDHIIJEEAGGFIIIECCAFFDGHIJIJEGE?E@?DEEBCCCBB,8=ADD?@CCCCDD@CCDDCBDDDCDD
@0TG
CCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTT
+
@@CFDADDFHDHHGIIGBHIIGGGEBGGIGBGDHI9FGGIIGGHDHDHIIIIIIIG9B;@CCEBDABDD?BDDCDCCCAACACCDCBCDC3:A@CDDD@C
@0TH
AAACCTTGCTCCTTTACAAGAGAGTCAGGAGTCTTACACAACTGGGACTCCCAAAGCAACATCTTCTCACCAGGGCCTTGGAAGCACTTTGCCTAGAAGGG
+
?@@FDDFFGHGHHIIIIIIC;?AEACHI9EEFCFFGGHIIIEIGGIGICHIIIIGHFGIIIICEHGDHHIGHHFFFFCCCCCCCCCCCCCCCCCCCCCCCC
@0TI
CCTCTCTCATCGGGAAGCCCTGGCTTACATGAACCACATCATGGTCTCTGTCTCCCCGCCTGAAGAGCACGCCATGCCCATTGGGAGAATAGCAGACTGT
+
@<@DDDDDFFHHDCHEE+AEBBBCGGHGIIIIIFGEHGHIIIHGIIIIIGEHAFHEH<EHEEHCEBBDCC?BBBB>CCC@CCCCBBBBBC@ACCCCBCC@
@0TJ
CGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTT
+
C@@FFDFFGHHHFIFIIJIJJIGGIGIGIIIHHGIFIJJIIIGIIIGJGIJIJJJJIJIEFHGFFFFFECCCEDDDDACCCCDBD=@AC?BCDDDD:ACCD
@0TK
CCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGAT
+
@@CFADFFHGHDHBBAFBEECFHEHIGGIIGGGEDIFGGGDHGIIEIIIGGGIDHIIIGEHGGGGIIFEEHEEBFBECECCACCCC>CCCC??C?B>@@@A
@0TL
CTGCTTATTTAAAGGATCGCTTTGTGTGATTAATCCCGAAAAAAAACCAGACACTAGAATTCAAACAAGTTAGGAGACACCCGAGGGGTCGGCCGCAGGA
+
0((22))))))))2.()2((36?84));))))1))))((((7(('-'(6(.5(.)).))(.((..((7,((-((((,(,(,&)0-5-&))&)0&)&&&)+
@0TM
CTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTAT
+
CCCFFDFBDHHHHIGIAFGIGIIIBGHGGIIIIIIIIFEIA;AHGDDEHIGH7?CEEBCDDFEECAECCBCCCCCC@CCC5@CCCB8ABBBBBBB>A??@C
@0TN
AGAGGACAAGTGCAAGCCTATGTCCTATGAGGAGAAGCGGCAGCTCAGCTTGGACATCAACAAGCTCCCCGGCGAGAAGCTGGGCCGCGTGGTGCACATC
+
CCCFFFFFHHHHFIJJJJJJJJJJJIJJJGJJJJJGJJJIJJJJJJIJIJIIJIIIJJHHHGHFFFFEDDDD@DBDDDDCDDDDDD@@D5>B?@CDDDDD
@0TO
AGTAAGGGGAACCCTGTCGGACTGCGCAATGCAGATAGCGACTAGCCTGCACGTGGGGATCCGTCTAAGGGGAGGGGTGCAGTTCTTCGTGATGACCCTG
+
(0-((46(@(:5(:(.))(2((((.((-7=0)).9))0)7'''-);)8=:6)(635'9(3;(,88,(::(20&0&)&)522(+(+(+(++26(5:(((32
@0TP
CCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTGAGTTGCTAAGAGAGAAAACCAAATAAGAAT
+
@@@FFFFFHGHHGHGIJJIJJIJIFGIIIJGGIIJJIJIFGIJHIGIICGHJJJJJGHGIJJJHHEEEF;@CCCDCAEDDDDDDB@DCCCDDDDDDDDCDC
@0TQ
AAAAAAGAGGAATCTCATTCTAATGATCAAAGTCCACAAATTCGAGCATCACCTTCTCCCCAGCCCTCTTCACAACCTCTCCAAATACACAGACAAACTCC
+
CCCFFFFFHHGHHJJIJJJJJJJJIGIJJJJIJGJJJJJIJJJJIJJJJIJJJJGIJJIJJIIIHHHHFFFFEFEDDEEDDDDDDDDDDDDDDDDDDDDDD
@0TR
CAGACATGGAACTTCACATCAACGAGGAGGACACAGGGCCTCTTTCTCACTTTGTTGAGAGCATGGTCTACATGCCGGAAGGGGGCTCCTGCCACCCCCAC
+
;95=9()))9@7)2<9@847):@2;;/@58=:=>=((0=?;>3>?>3:..:>;3)8.;83)=)<1()89)813;88=5;/2,53)-0(2((/((+28-55:
@0TS
CAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTC
+
@@@DF?DDFHFGHII1<ADGHIIGGE*CBACEDGGGHCEDCAGG;FHGGGIIGGHEHHBEEHGBDHB=?BB=@CEE:;>;;;>A;;5>>>3>@AC9?>9(
@0TT
AGAACTTCAGAAGAGAAATCGTAAAGACAGCCAGTTCGAAACTGATATAGTACAACGAATGGAACAAGAAACACAAAGAAAGTTAGAACAACTCCGGGC
+
@@<DADABFHHFHIGGGGHIIHIEIEGHHIEGDFFHBFGHIBGBFHI@BFHB<FHIFGEGGDCG>E=>EHFAD9?DECEEECCCCCCCCCCB>:@BBBB
@0TU
ACGGTTTCGCCGGCAGTCTCGATGATAGTATTTCTACTGCAAGTACTTCTGATGTTCAAGATCGCCTGGCAGCTCTTGAGTCACGAGTTCAGCAACAAGA
+
=:=:=:A:?@?D?81)1:CDA9?D?D?DDBDC4DD**?8??9<.=C<)7==@C@C;@C@D@=)6;49?(66=?3-5>5>>5:::;=;2<:34:4++8><<
@0TV
TTTGAACTCAGGGTCACCACCAGCTATTGGACCTTACTATGAAAACCATGGATACCAACCGGAAAACCCCTATCCCGCACAGCCCACTGTGGTCCCCACTG
+
CCCFFFFFHHHHGIHIJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJIJJJJJJJIJJJJJIIHHHFFFDDDEEDDDDDDDCDDDDDBDCDDCDDDDDDDD
@0TW
AGAATCTAATCTTGTTGAGGGTAGAGAACCTGAGACAGTGTGAGGGGGGGGGGCCTGCCAAGCAACCCTAAGAGCTTGGGAGGAAAACTGAGAGAGGGTCT
+
(07(::9@>9).6)2)2@4)3;==:>;)==<<?><1911<==>=(<95&)5&&&)27875:(2(896-82282(2::<<5685<835(8(+6:;9638(52
@0TX
CCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCC
+
CCCFFFFFHGHHHIJJIJJJIGIIJGHFHIJJJIJIGGIDHIJGGGFGGHJJJJJJJJJHHHHCEEFFFFFFEEEDE?BBDDDDCABCDCDCDECCDDDDD
@0TY
CAGCGAGAAAGGAAGTCATCTTCATCCTCAGAAGACAGGAATCGAATGAAAACACTTGGTAGACGGGACTCGAGTGATGATTGGGAGATTCCTGATGGGC
+
@?@AD@DD8;A:;EE2+<?EHAEEHB9CFHHIE3**1:?80BB;?@8?BFGGACDGGA>F@7==;;4',67;;A;?CB;;B@;9<91;:>>@C@C<>@<2
@0TZ
CTTTTCTCCTCTGTTGGAAACCATAGAACCTGGCAACATACTAGATGTTAAATATGACTGTGGCCTCCAACTAAGGGTCAGCGAGGACACCTGCCCACTG
+
=@@;;BDDDF>B:A?B?F>3:FEFCB+2++<?)1?*)11CB4BF??F<D9??*0//?94B))888C=2)..7)@=EF;?@?;><3>/9?95?5(,5>B@A
@0U0
AGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAAC
+
@@@DDFDDHHGHFIHGIHJDHEHIJJJJJHHIHIJGEIGHIJJGEGIGEHHHCFEFDDEEEEEDDCC?B?BDDBDBBDDDCDCDDDDDDBDCCDDDDDDCA
@0U1
GTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACC
+
@BCFFFFFGHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJHHHHHFFFFFFFEEEEEEDDDDDDDDDDDDDDDDDD
@0U2
AAAGAAAGAAAAACCACAAGGACAGAGAGAAAAAAAAGAGGAATCTCATTCTAATGATCAAAGTCCACAAATTCGAGCATCACCTTCTCCCCAGCCCTCTT
+
<?<DDDDA?BFHHIGI?=ACAFG;?G?):??GIIBGBAC;C;D@AGEECAAHEEEEB@CCECC>>CCC@BBCCCBCCBBC@C><CCCCCCCB@@B??CBCC
@0U3
CAAATACCATAATTACATGCGGTAAATCTCATATTTTCTTCTGGACCTGGAGCGGCAATTCACTAACAAGAAAACAGGGAATTTTTGGGAAATATGAAA
+
CCCFFFAFFHHHHJIJIIJJIJIIJJJIIJJJJJJJJEGIIJIJJJJJJJGIIHIIIGIHHHHFHFFFFFEEEEEBCDDBBBDDDDDDDDDDDDDDCDD
@0U4
GGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCC
+
@?@F?DFDHHHGHGIJIIIGHGGGG9GCEGGGDGDDFBFHDGGIII@FHICF@F=CCHACEGE@E=?ACECDDDB@C;A@@;;?>>CC@CCA@>CB<<AC<
@0U5
CTAACTCTCAAAAGGAAAAACTCAAGGAAGAACTAGGACTAATTTTAGAAGAAAAGTGTGCTCTACAGAGACAGCTTGAAGACCTTGTTGAAGAATTGAGC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJIJJJIIJJJJJJJJJJJJJJJJJJJJJJJJFHHIJJJJJJJJJJJJHHHHHFFFFFEEEEDEDDDDDDDDDCDDD
@0U6
TGGGCAACAAAGCTATGGAACCAATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTT
+
3(-(()2(<?(4))2>8)::=>((;1=?<<=(3==;?=:1=1)).<=893=1)).77=?>).;;07;>8>8)(6398;5;7/(,;65;<:<:(286;</5(
@0U7
CACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGC
+
C@CFFFFFHHHHFIEHGEHIIJJGGFIGIEHIIGIIJJIJGICHIIEFHIIGIIBFHHIGAGHIGGAH?EEFDFFDFDCEEEBCACCDBDCBABDBD@9CB
@0U8
GTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGAT
+
B@CFFFFFHHHHFHIJJJJJEHJJJJJJJJJJIIJJJJJIJJIIJJJJJJJJJIJJJJJJJIJJHHHHHFFFFFEEEDEEEEDDDDDDDDDDDDCEDECDD
@0U9
GCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGG
+
CCCFFFFFHGHHHJJJHIIJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJHHHHHFFFFFEDDDDDDDDDDDDDDDDEDDDDDDDDDDCDDDDCDD
@0UA
CGACGAGATTGAAATCGACTTTGAGACCCTGAAGCCGTCCACACTGCGTGAGCTGGAGCGCTATGTCACCTCCTGTTTGCGGAAGAAAAGGAAACCTCA
+
CCCFFFFFHHHHGJJJJIJJJJJJJJJJJGJJIJJJGGHJIIJIGGIJHHIHHHHHDEDCDDBBDDEDDCCDDDDCDCDDDDBBDDDDDCDDDDDDDDD
@0UB
GGGCTCTCCCAAATGCTCCACATTGCCAGTCAGATCGCCTCGGGTATGGTGTACCTGGCCTCCCAGCACTTTGGGCACCGAGACCTGGCCACCAGGAACTG
+
?+=DDBD>DDDDBBEI<EFE:FECFEEECE3E>A@@?@D0?DDA??<<?)8=C9@8C9CDADCCCA?D@AADA(9;>>>;?=???>>8<1(88<>>>><A3
@0UC
TACCATGTTCATTCCTTCCGATGTTGACAACTATGATGACATCAGAACGGAACTGCCTCCTGAGAAGCTCAAACTGGAGTGGGCATATGGTTATCGAGGA
+
@@@FFFFFGHHGHIJJJJJJGIIGIIJIJJJJJJJIJIJJJJFIIIJJIGIJIIIJJIIIJJJJJJJJGHFEFFHEFCB7>ADDDDCDDDDCCDDDDDDB
@0UD
CAACAACAGGGACCAGATAATTTTTATGGTGGGACGAGGATACCTGTCTCCAGATCTCAGTAAGGTACGGAGTAACTGTCCAAAAGCCATGAAGAGATTA
+
@<?ADDDAAAFBHEBCGFHDFHIIIEH@?EC@GC8?:?@@GEHGI8CDACCHG@GA@?EE7?E>B7?749AC;>CAD@C:>AACBC?95@::AC><9CCC
@0UE
CAATTGGTTTGCTATTCTGTCGTGACTCTGTAGGCTCCATCATGTAAACCCACACAGCAATCACCTATAATCGAGGCAGGTAGAGGGGTGGTGGAGTTAGT
+
(0((28)@(6()))2)))):13<()-)).)):)))3(())).))0)))))((091(.().).))).))..>15(33'8/',-6((('''&&)++(((+(++
@0UF
CCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTAT
+
?@@DFFDDFHD?;<FHEGCIBHBFHGC<BGBFFH@DAGHIIIGIAEEEIDCHHHFBD>@CAACED>@@CDCCDDDDDDDDD@BDCC@:8<A@?ABBCDDCD
@0UG
TTCTCACCAGTCCGTCTCCTTCAAAATCCATTCCAATTCCACAGCCCTTCCGACCAGCAGATGAAGATCATCGAAATCAATTTGGGCAACGAGACCGATCC
+
@CCFADBDDFFHFIFHGIIIGIIIIIGCEGHIIIDHEHBGGGEHIIGIIIIIIIIIIIIGCEGEHH?HEEBDFFFDDCE@ACCD>@BDDDDDBBBBDDDB@
@0UH
CAGTGCCGAGTTACGCTTCCTCGACGCCACTTCATGTTCCAGTGCCTCGAGCGCTCAGGATGGAGGAAGACTCGATCCGCCTGCCTGCGCACCTGCGCTTG
+
???D?B+0<DFFHBCAFHIIIIIAH@GHHIICCEGBFBHGGG<@@C78A@AADE=ACCC;@@?(9B?A?ACCC@<><@ABB7AABCCA9>B@BCC?<>BBB
@0UI
CAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTAC
+
@@@FFFFFFAFFD<GHBGIGCEHGHGIIIIIDHGGIIIGEHGIIFGIFGIIIIGCHHGEEFFBCECCCCCCCCACDCCBCCCCC@>CCCCCCCBCCC058@
@0UJ
CGAAGAAGAGCTTTCCAAACTGAAGGAAGATTTAGAAATTGAACATCGAATAAATATTGAAAAACTTAAAGATAATTTAGGCATTCACTATAAACAGC
+
CCCFFDDDFHGHHGIJCGIIIJJJIIJEFGIIJJJJIJJJJJIIJJIIIJGIJGIIJJJJIJIJIGIIIJIJIGGHHGDHHFFFFDCCEDEEDEDDDD
@0UK
GTTTATTTCATTGCATCAGTAGTAGTACTATTTAATTATGAGGAGAGAACTCAGCGACACTACCTGGGCCATACAGACTGTGTGAAATGCCTTGCTATAC
+
?1=?DBBDBAD=AEFFGIF<<<ACFEEHBHIE@9CFEF@<?EF31:?GB@FFFFG@0@FFII@=@@ECEEF>;.?;7;7(((.6>A@(-;>;5:>:@;@:
@0UL
GCCTGTACAATGTCAGTGCCTATGATCAGAAGCCACAAGTGGGAATGAGGCCCTCCAACCCCCCCACACCATCCAGCACGCCAGTGTCCCCACTGCATCAT
+
@C@FFFFFFHHGHIIIGEGIHIIEGGCGGGGCGEG9EEEDD?D@DDGAG<DBFGC(8FFHGGGF9A9=?BACCA::>9?09B<>@@:ACC@CB?A:(:>>:
@0UM
CCCCCCCACACCATCCAGCACGCCAGTGTCCCCACTGCATCATGCATCTCCAAACTCAACTCATACACCGAAACCTGACCGGGCCTTCCCAGCTCACCTCC
+
@@@DBDDDFFHDF<FEH@GBFFGEGGFD9BFHECEG@FGGIGIIGCHFAHFEEEB@DCCC:>CC@C>CC@BBBBA>??CCBB@BBBCCC?:@AA:@C8@BB
@0UN
GTCCATACCAGATAGCAGCTACCCCATGGACCACAGATTTCGCCGCCAGCTTTCTGAACCCTGTAACTCCTTTCCTCCTTTGCCGACGATGCCAAGGGA
+
?11=BDDBDDDDDE@E4<CAEFEDB?AEFI>EEDDDDEIICDDDDDDAAC>C@CEEID?=A6?;@?;>>;@AAA>5;5>>A>>A??=>>??>>AA???8
@0UO
GCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCC
+
@?@FBDBEFHFFDAEHIIIIIEEGGEDHGGI>EEEHGID>FHGGHGHGGC=GGGDHECCDFFF37>A@B>CCC;ACCCA@CA?ABBB&0<ACCCBBCBBB
@0UP
TCTCGGGAGGGCACGGCCTCCCTGTCCAAGAGCAATGAAGAGATTAATGTTTGAGTGCCTCAAAAAGAAAAGAGATGAGAGACCACTCTTCCCCCAAATTC
+
8(-((2((0:90-<(-(1(((7:<00).0)(9)).)7)/.3;):>3==))))).(..)))))))((3,73,((,(,(7,,(,77/66::/(8:7-062(8:
@0UQ
GGTGATTCCACACTGGGGTCTTCCAAAGAAACCCTTCCACCCACATGCCAAGGCAATCTCCTTATCATGGGGACTGAGGATGCCTCCTCCTTGCCTGAAGC
+
=?+=?BDD<=?ADBAACE8@FEB?AFF;B;EE9B>DC*?:8@;D1?BDEC<C@=@CEI:CDEC)=CA3?DDDD6;>6;;A5;>A>>?9<:9>A>A>A?>A>
@0UR
GGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACAC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJGHJJIJJJIGGIJJJJJJJJJIJJJJJBHIIJJJJJJJIJHHHHHFFFFFDDEEDDDDBDCCCEEDDDDDDD
@0US
AAGAAGAGCTTTCCAAACTGAAGGAAGATTTAGAAATTGAACATCGAATAAATATTGAAAAACTTAAAGATAATTTAGGCATTCACTATAAACAGCAGAT
+
@@@DDEFFHHHHHIIGGHGGEHEEEFGHEHHGHFGBFHIDBDGHGGEGHIIIJIEEIHIGIJGIIGHHEGIIEGGGEHHHHHBEFDEFCCCCCCDDDDDD
@0UT
TGGATTGAAAACAAACTCTATGGCATGTCAGAGCCAAAATAGCCCGGAGAGAGTCCGGTACCAATCACGAGAGCTTATGGCACTAACACTGGGATTTCA
+
++=A7+2+?AC=7+<7A=<@,3+<A+2?=7=A*:)*):)******0=A0A(5()8.('-5=)).)6>(((','5,(,59((,,3(+(8+:((((+((+(
@0UU
GCTATGGACAGGCTGCTGTGGGGGAGGAGTAGAGAGCTTAGAGGGCCCCGCCCACTTAAAAAAAAACACAGACCACCCAGGCATATGGGCAACAAAGCTAT
+
;55((..))2(((.(()2)))(:(1(0(())).9)((<9))))(-'-5'5',''(,(,8((:27&))82:66868<<5<<<<<==:<:;;<8<<<<<7665
@0UV
AGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGG
+
@@@DDBDDFFHDDD<AHICHEHGFGHF@HEHE?CEGDCGDHDAGGGGHIIGHIGGCHGIHEAGG>D@@EHHHFEEEDD@CCC>CCCCCCC??@;BBBCCB
@0UW
TGCGTCGTGTAGGGGAAGTTTGTAGATCTCCAGGGTCGCCTGATCATTAAAAAAATGGAACGTCACATCAACGAGGAGGACACAGTGCCTCTTTCTCACTT
+
-((-:58@/=<))((((())2.(:=??<)))).):=?/(<'(.;.=9)=)<)=5=(((.:;;39;;<===7;<;9996066;9/5;::<<6:426:<=:<:
@0UX
CCCACACCATCCAGCACGCCAGTGTCCCCACTGCATCATGCATCTCCAAACTCAACTCATACACCGAAACCTGACCGGGCCTTCCCAGCTCACCTCCCTCC
+
?@?DDD;DHAHBFDGID?FFEEFHGECGGGGIDH>DD@FG@BBGGGIGEBEIIGIGGHIIG>GHGHHEECC@CCCCBBBBBBCACCCCB4>>AAC?BBCC@
@0UY
CCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACGACCCCAGGAGCATGGGTGTTTATGGG
+
<??ADDD?DDAD=BEEEEE?+33??@CB+<A@8?;*CCBC:BD?;?*?ADAAA@A>;;)7).)7=)=9<<@@=2'33;608<(+8(((4<<3502(((4><
@0UZ
TATGAACTATGATAAACTTAGCCGTTCACTCCGCTATTACTATGAGAAAGGAATTATGCAAAAGGTGAGCAGCTAATACAGCATTAAAATTCATTGAAATG
+
CCCFFFFFHHHHHJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJIJJJJJJJJJIJJJJJJEGIJHHHHHFFFFFFEEEEEEEDDEDDDDEDDDDDD
@0V0
TAGCCGTTCACTCCGCTATTACTATGACAAAGGAATTATGCAAAAGGTGGCTGGAGAGAGATATGTCTACAAGTTTGTGTGTGATCCAGAAGCCCTTTTCT
+
@@@DDDDFHBFBHIEHIEGGCHHHIEHIGGGIBEGADFDGHGIBH@G*96==;AA=8@@ED>CEEA@EDDFF@ECDE;>;=;?ADDCC@CCDCBB?CCD4@
@0V1
AAATCTTGGATTATAATCATGAGATTTTAGGACAGCAAATTAATGACTTTACCCTTCCTGATGTGAACCTTATTGGGGAGCATTCTGATGCAGCAGAGCTT
+
<@@FFFFFHDHGHJHGHEIIJIGEAHHGCBFHEHGGGIIIIJIJGEGIIIHHGHGIJIIGGIBCGIEFF=CHIIHHJF?<>BDEECECDEDDDDDD?BCDC
@0V2
CGGGAAGACCTGGCTTACATGAACCACATCATGGTCTCTGTCTCCCCGCCTGAAGAGCACGCCATGCCCATTGGGAGAATAGCAGACTGTAGACTGCTTTG
+
CCCDFFFFHHFFHIIJIJJEHIIGIJJJGGHIJIGGHIGHDGIIJIJGIGIJIJIJJJJJHHFF?DFEEEEDDDBDDDDDDDCDDDDCC4@@CCCCCCDDC
@0V3
GTCTGAGCCAAACATCCCCTTCCCACCACAAGGCTTTAAGCAGGAGTACTACGACCCAGTGTATGAACACAACACCATGGTTGGCAGTGCGGCCAGCCAA
+
:??A++=DD;+A;:<<+AEF@@?B@2@8??):?)99B@D<B@>9@1?@D)8=B0@;A2==7=AC?;@@A@;5;6=>25555>785>1(+:0&5&0<>8><
@0V4
CGGGACCCGAGTGATGATTGGGAGATTCCTGATGGGCAGATTACAGTGGGACAAAGAATTGGATCTGGATCATTTGGAACAGTCTACAAGGGAAAGTGGC
+
@<?D;DD;?8@22<CFA@FHEFFGFBBBG>CCGFDD<9@@GFFFEFF8C==;;FFIEII<@E<=C?BD;776;@B@ACCB@?@A;@BA@@?<BB@@44><
@0V5
TATCGAAGTCCCTAACATGGGCTTTAAGAATCCCGCGCACCAGTCTGGGCGCCGAGCGCCGAGCAAGTGCAGGGGACGGCGTGCAGGGATGACAGGCAGTT
+
0((2(2)2=6>>)4661111(()2:)28)).1))1((-7-9:().))))(-''',','''))&00+/+(+((6&088&)&&)&&+253(((+((8(+((((
@0V6
ACTGCATCATGCATCTCCAAACTCAACTCATACACCGAAACCTGACCGGGCCTTCCCAGCTCACCTCCCTCCATCGCAGTCCATACCAGATAGCAGCTACC
+
@CCFFDDFHHHFHHGIGHIGCGGIJJJJJJGHJGGEGHJJIJIGGGGGGGGGEHFCCCEEDCEFEECDDDDBDC:<@8@<ACDDCDCDDDDCA>@C@?C@C
@0V7
ATGGAAGGTCACATCAACGAGGAGGACACAGTGCCTCTTTCTCACTTTGATGAGAGCATGGCCTACATGCCGGAAGGGGGCTGCTGCAACCCCCACCCCT
+
@@@DDD+2=CAFFGEBGEHHEE:?C;GHEGHDGFDGFAFHGG9BDHGHG9<C9FHBGICGEBEC@EHE>.=<BA:>?B:=>B9@CCCCACBBB<<59@B?
@0V8
CAAAGCTCTCCTGCTGCTGACCAAAGAGGACTTTCGCTATCGATCTCCTCATTCAGGTGATGTGCTCTATGAACTCCTTCAGCATATTCTGAAGCAGAGG
+
?@@DDDFFGAHH8DFGHG@HIIIHHGEBG;?EDHAHIFIGEGG?GGIEE@BCCGHGI8@GGG)=@EEIHCCEEH:BEFFDFDC@@CEDEDE@CCACCCB<
@0V9
CAGAAGAATTGACTCTTCAAATCAATGAACTTCAACAAGAAATTGAAATACTCAGACAAGAAGAAAAAGAAAAGGGTACATTTGAACAAGAAGCTCAAGA
+
((78(.):)2))))2)6=>9<484@??<4=8=?@?)9(1)66>?>;91::=9<13=<=9:==;71>67;/0;;)(((.))).;19;7=>0;<>0:;(:;5
@0VA
CCCCTTCCGCACCCGCCTCGGACTCTATTGGGCCCCAAATTCTCACCAGTCCGTCTCCTTCAAAATCCATTCCAATTCCACAGCCCTTCCGACCAGC
+
CCCFFFFFHHHDHGIIGGGIJAGHGIHHIIJJJJIJJIHGIGIIIJJGIEHEHHFFFFDDEEDCEDDDCCCCDCACDDDEDDDDDDDDDDDDDDDDD
@0VB
CAGGGTCACCACCAGCTATTGGACCTTACTATGAAAACCATGGATACCAACCGGAAAACCCCTATCCCGCACAGCCCACTGTGGTCCCCACTGTCTACG
+
CCCFFFFFDHHHHIGIJJJJJJJIJJJJJIIJJJJJIJJJIJJJCHIJIJJIJJJJJJJJHHHFFFFFCDDDDDDDDDDDDDDDDDDDDCDDDDDDEDB
@0VC
AGCAGAGAATAGCATTCTTAAAGATGAAAAGAAAACCCTTGAAGACATGTTGAAAATACATACTCCTGTTAGCCAAGAAGAAAGATTGATTTTCTTAGACT
+
<?@DADDBAFFFFIIGIIICFGIIIIIIICHHGIIIGGGIIIIIIH?FHB<GDDGGHHGGGHCGIGHIFGEHIHG@AAEHFFD@BEEDDCCEDECCDCC@A
@0VD
CCCAACGTACGGCTCCTGGTTTACAGAAAAACCCACCAAAAAGAATAATCCTATAGCAAAGAAGGAGCCACACGCCAGGGGTAACCTGGGGCTGGAGGGA
+
;;((--(.2=??:;8@)<=.@@16).)))2.;33-0876.(<4(.:9;.:>31;;>13).6>70((959(979/'7',8;6&08/2:<<<&5:&5:7955
@0VE
TGGAGGAAAACCACTTCATCCACCGAGACATTGCTGCCAGAAACTGCCTCTTGACCTGTCCAGGCCCTGGAAGAGTGGCCAAGATTGGAGACTTCGGGATG
+
@@@BDDDEHHHDHIJIIJGHIJIJJJIJJCGHIJIIHIGHGGHEHJGGGGIIIFHJJF@7@>@@EHF=BFDCE>A6>@DDDDBACDDDCCCBDCCBBDD@D
@0VF
CCGAACTACACCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATGACATCTCCTGTGACTCTCACCTCTCAGACAACTAAGACAGATGACCCCCAATTG
+
CCCFFFFFHHHHHJJJJIJJJJIJJJJJJJJJJJJJJJGHJFHIIJJJJJJJJJIIIIJJJJJJJJJJJJJJHHHHHFFFFFEEEEECDDDDDDDDDDDD
@0VG
CCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGAT
+
@@@DDADDHHHFHGIGIIGGGH>HFHEEBBFECHJEIJFIGIG@BAGHGIGEICHIJBH>FEH>FG==>CEHDFBDF>CACC>@>CCCCACDDD=<<@BD@
@0VH
AAAAGTTCTGTCTTTGATGAAGACAAAACTTTTGTAGCAGAAACATTGGAAATGGGTGAGGTTGTTGAAAAGGATACAACAGAACTCATGGAAAAACTTG
+
;?@DFBADDHFFHGEHIIIIIGIIIIGGGGIEEHFHIIIIIGHIIIIII?DGGGIIEG9FHFEHIGGEHIIIIG:ACHD@?@DEDC@ACDDCDD?A=CCA
@0VI
ATCAAACTTATAGATATTGCACGACAGACTGCACAGGGCATGGATTACTTACACGCCAAGTCAATCATCCACAGAGACCTCAAGAGTAATAATATATTTCT
+
CCCFFFFFGFHHHIIJGGJJIJJJJJJJJJIIJJJJJIJJIIIIJJJJJJJJJJIJJJJJCEHHEHHGFFFFFEEEEEDDDDCCAB:@CCDDEEDDEEFFE
@0VJ
GGGAACCAGGAATGCCATAGTTCCGAGAGAAACTTCTGTTAGTAAAACACACAGGTCAGCAGACAGGGCCAAAGGAAAGGAGAAAAAGAAAAAGGAAGC
+
C@CFFFFFHDHHHIFIIIJJFGHGIJJIIIIGFEHIGGFGGH@FIIIJEDHIJJJ@FGGGIJIHHEEEDEBDCECAD;AD=BBDDDD=?ADDDBBACDB
@0VK
CCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGG
+
C@CFFFFFHHHHHJJIJJJJJIJJIJJIJJHIJJJIGHHIJIJIJJJIJJJJJJJJJJJGGJJHGGFDFEDFEEFEEDBDBDDBDD@BDDDDD@CDD@CCD
@0VL
GTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACT
+
C@@FFFFFGHHHDHJJJJGGHFHHIJJIHIJJJIIGIJJIJJJGIIIGIGGIIJJGIJJJJGGIGIGHHHFHFFFFEEECEEDDDEDCDDDDCC?BBBBBB
@0VM
CGAGACCTGGCCACCAGGAACTGCCTGGTTGGAGCGAATCTGCTAGTGAAGATTGGGGACTTCGGCATGTCCAGAGATGTCTACAGCACGGATTATTAC
+
+=@DDDDD>FHHDDCCCGHIIII>GCGHGGEEHHGHDHI;9BAFFBCC@F@@FGGE@BCABE@BB?AB?;;@;:>93>55:@CCCCCCB><-5>:CCCA
@0VN
GTCATCTTCATCCTCAGAAGACAGGAATCGAATGAAAACACTTGGTAGACGGGACTCGAGTGATGATTGGGAGATTCCTGATGGGCAGATTACAGTGGGAC
+
CB@FFFFFHHHGHJJJJJJJIJIJJIIJJJIJIJJIJJJJJIJJIIIIIJIJJEIJIIHIGHIJHHHGHHFFFFEEEEEEDDDDDDDDDDDCDCC>CDDDD
@0VO
CAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJHGHHHGFFFFEEDDDDDDDACDDEDEDDDDDDDDDDDDDDDD
@0VP
CTGGATATGCAGGTTGCAGCATTGCAGGAAGAGAAAAGTAGTTTGTTGGCAGAGAATCAGGTATTAATGGAAAGACTCAATCAATCTGATTCTATAGA
+
?@;BDDDDDAFHFIIIB@FG:<<AF>CEFC?CC9??FDHDFHHHHIIGIIG;?D;FG>BB@@FEE@=C@A@HA?E;>BDDEEC>@CCD@CC;(>>CAA
@0VQ
CTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGC
+
;?@DDDB=AFF?FGCGHGEIIIBBEGIDIICFH>@>F?FGGGDDGHICGIIHIIIIIIIIGIIGAECEA;BD???;;>C>CCCCC?@A?BCCCC?CBCCC
@0VR
CAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACC
+
@CCFFFFFHHGGHJJJGIJJJJJIJJJIIIIIJJJJJJJIJIJIIIIJJJJJJJIJJJGHEHHFFFFEEEEEDDDDD8?CCCDCDCDD:<CCDDDDDEEDD
@0VS
TTTCTGAACAATTGAAACAGAAACATGGTGAGATTAGTTTTCTAAATGAAGAAGTTAAATCTTTAAAGCAAGAGAAAGAACAAGTTTCATTGAGATGT
+
@@@FFFD?FFHHHIIIBEGIDAFEIEHGIDFGBFHABFHGIIIIEGHIECBBBHEE?B@FDFGGGECHDF=CACHGI>@6=CHF>CDECFACC>;C;-
@0VT
GCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATAC
+
C@CFFDFFHHHHAHHGGFGHEHIJIIIIIHIHFIFFHHIJIGIJGHJJIIJJEFEEGIHHHGHDBDFDEEEEDDDDDD8;>><?:CDA?>?CDDDCCCCC@
@0VU
ACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCA
+
@@@DDFADHFFHHIIEFIGCDGGEEHHIIIIIIIIIGGHFHIGFG>?FHHIIBCA@FDHGIGGFHFHHFDDFEFCCCC?@DBDBDDD>(:<AA@@CCBB
@0VV
CCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACAC
+
@;@DFFFFHHHGHIIEHIIIGEGGIIIIIIIIIIIIIIIIIIIIIIGIIGIIGIIIIIDHGGHBHE8EBDFFFFFEDECCDDDDDCDCCDDDDDDDCCCDD
@0VW
AGGGAGACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCT
+
<@@DFFFFFHFDD:C;??D>CGGHIBA?D>DEEHIIFDHCHC@;CHE=9BDC?<>B8@:ACBCCCCCCC>CCCCA<@C>ACA<5<59<BA>@<<A@:BCAC
@0VX
CAGCGAGAAAGGAAGTCATCTTCATCCTCAGAAGACAGGAATCGAATGAAAACACTTGGTAGACGGGACTCGAGTGATGATTGGGAGATTCCTGATGGGC
+
@?:BD?@DFFF?AFEAE:CFEFHFIIIB>GFFB9DC?DC@FBF8?DFFIIIE>FFIIIIFFFF@EEEAD2;@;8;?ABB:;>A?@@83:ABB@>44@@?B
@0VY
GCAGTTACAAGCCTTCAAAAATGAAGTAGGAGTACTCAGGAAAACACGACATGTGAATATCCTACTCTTCATGGGCTATTCCACAAAGCCACAACTGGCT
+
@@<DDD,2AFDFDHIIIIIIDIHIIIDHHIIIIGBFGGHIIHIIIIIIIIIIB=@GHGIGHIEHIIIIIIGHGFHEFFFFEEEEEDDADBDDDDBDDDDD
@0VZ
CAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTC
+
@@CFFFFFHGHFHIJJIGBHEHIJIJIIJGCEHGIJIJIIGIJJJJJJIJHHHJJJJIJJJJJJIJHGHECDFFFCEEECECDDDCDCBDDDDBCDDDDDD
@0W0
GAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACT
+
C@BFFFFFHHHGHJJJIJJJIJIJJIIJIGIJJJJJIIIJJIIJJJIIIIJJIJJIJGHIJIHHHHEHFFFFFECEEEDDDDDDDDDDDDDDDDDDDDDD
@0W1
CTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCTACTGCCCCCCAGGCATACAGCCAGCCTGTCC
+
CC@FFF+AFHHHFIJJJJJIGHIJIJIIJIIJIJJJIIJJIJE@GGIGIGIIGIFCHGIHHHAHEFFFFFFCEEDDDDDDDCDDDDDDDDDDDDCBDDD
@0W2
CGAGAGTGATGCACAGGGATGGGGACACTCTGCCATCCCCCAGCAGCTGGGACCTGCAGCCAGAACTCGCAGCTCCACAGGGAACTCCGGGACCCTTGGGC
+
;(7==522).:=<989???@=:<(<=@><>?3=?;8>17;?81=<395=99(63...8:::===)6.9/'9;8(;;;;;;<<32::6:995&0(2686;3(
@0W3
CAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCAC
+
?@;DDDDDDFFADC<A?DBE;E@CGIBDDEG>FFEFGGFA?@@>?DDFDCFFIIID2=.@DAEC7A?3.;?BDDCC;>A?=ABBBBBBB=@?<?@BBBB??
@0W4
GGAGGTACCTCTGTTCAGGCTACGTCACTTCCCTTGTGGGAATGTCAATTACGGCTACCAGCAACAGGGCTTGCCCTTAGAAG
+
1=?+=DDAB4C<C,22CEEIIIIDABF1F<?E;:*:*1168*)?D*9DDI@?6?@'@;8@C=7@===??=6.9;;.;;>>A;(
@0W5
GCAAGCTGCAATAGTTTCTCTTTTCTAGGGCAGCTGCCGCAACTGTGCCTCCACAGGGAATCACACTGCTCTCCGTATCCCCAGGTACTAGGGTTTCTCC
+
?8=D:2ADADDD>:A@DE,<FBCDE<CEEBFEECE<;CDDA<@D>BDEEDCCDCAC;@C26@AC>CADAAD3@A?@>5=>A???=A>A:>5>=+8<AAA>
@0W6
AACTGTTGCACCGCTCCAGGTCACCTATCACGACAAATCACCGGCCTTCTCCTGACCCCGAGCAGCGGCCCCTCCGGTCCCCCCTGGACAACATGATCCGC
+
@@@ADDDD>DF;?C@FGH>G<C<EBEG@GBGBFGGECF@DD8?@F<AH<@DAC>EHBB53>BBB?5=88@;@89<<B0<9BAB9<?A8?CB<<3::+:@8?
@0W7
CTTATTTGAAAAATGTCAGTACAAAGGTATTCTGTTGTTTCATGTTTCCTGTGTTTAAAATGATTCTTAATACTGCTTTTTAGCCTTGCTATACATCCTG
+
C@@FFFFFHHHHHDIHIJJ4IHGGEHI:AEHGGIHGIEGIJJFHHIJIJIH@FFGHIIJJG>FHHGHJGGGEAEHEHEHJDEIEHH<EGDFFDDD<DCEE
@0W8
CAGGAGATATGCAAACATATCAGATCCGAACTACACCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATGACATCTCCTGTGACTCTCACCTCTCAGAC
+
@@<DDFDFFFDFDAEGIIHCHGHBHGHGFGIHCCGGIIIIIDGIIBGHBHGIGIHIGCGC;;C@CEDHIGGFHCEHEFFFFEEDECCEC@CBDDCA@>3,
@0W9
GCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACC
+
?;8BDDDBADFHDGGIIGIIAEDB<DFGGG4CCH>BFGABDGHGD<FHGEDADC;FGEG@=@@D>CGG7=AEED@D@DCCCCB?BBBBBC9AB<?@@CACC
@0WA
TGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTT
+
@@@BDDDDHHFHFIIE@B@EHG>FHG<HGHBGGEHIIIHIEGHADHIGCDHGHIGGIIIDGIIGGIIEHHFH@CDDC>@AC<@AA6=BBBCCCDCCCCCC>
@0WB
TGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGG
+
@CCFFFFFHHHHHJJJIIJJJJIIIIIJJJJJJJJJIJGIJJJJJJJJHJIIJIHHHGEFFDDEDEDDDDDDDDDDDDBDDACDDEDCDDEDDEDDDDDBD
@0WC
GCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGACAGCTATACCCAGGCTCAGACC
+
:?@DBDDBFF+C;FFFI>FA>3FACGFEEFIIIIEIF4?B?@@FFDFD>3C8BECFFEEFEFD7CEEFED=BDCCAB(6@;?BB>A;5:@B@?(,5>AB@
@0WD
ATCGTGCTGAAGCGAGAACTGGGTGAGGGAGCCTTTGGAAAGGTCTTCCTGGCCGAGTGCTACAACCTCAGCCCGACCAAGGACAAGATGCTTGTGGCTGT
+
:=:A=BADHHF?FEGGGHIGGGIF6CD>8CAFGCHEFGHGGG;8==BB=8;AFHE/A(6?@CBCCA=>A>>AC@B?@@B?8??BCBAC:AA:@C8ABBB22
@0WE
CAGAGATTTTGCATATGACTCAGAAGTGCCTAGCTGTCACTCCATTTATATGAGGCAAGAAGGCTACCTGGCTCATCCCAGCAGAACAGATGGCTGTATGT
+
3-(==?8>?@?>?@1)):.989.)3..:@).84=)).)):))266898>?=)))<3=(0.7)319)8)))((.=8???3))636.9(.(((-(,,5;230,
@0WF
CGGGCACTCCCTGTGGAGGCCTTGAGGGTCCTGCACCTCCATTTGTGACAGCATCTAATGTGAAGACCATTCTGCCCTCTAAGGCTGTTGGAGTCAGCC
+
???++A?3ADDDDCE+<AC=EE?CBE@7:?;C>DD<D;?BBDE4?93?DD9BC>C;CA>A77@D4@CDA:.=?3?;?A?936@@A5>;>;9((,:>>A<
@0WG
AGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTAT
+
??;;:0@A:C;:CCE@GGIHEHHE4C<<FFEGCEFFGFIIIIGD9B>GDCDDBFB2;=1)=@7@EC3?;C9@7?77;66>>6>BBBA<@>?AA9<<<ABBA
@0WH
CCCCTTCCCACCACAAGGCTTTAAGCAGGAGTACCACGACCCAGTGTATGAACACAACACCATGGTTGGCAGTGCGGCCAGCCAAAGCTTTCCCCCTCCTC
+
CCCFFFDFHHHGHGIIJIIIJIIJGEIIIIIHGHIJJJJJJJJIGHHIIIJJJGGGIJJHHEHDFFFDCEEBCCCDDDDDDDDDDDDDDDDDDDDDBBDCD
@0WI
GGAATTTTTGGGAAATATGAAAAGCCAAAATTTGTGCAGTGTTTAGCATTCTTGGGGAATGGAGATGTTCTTACTGGAGACTCAGGTGGAGTCATGCTTAT
+
CCCFFFFFHGHG?HIGJJJJJJGIJIJJHIIJJJFGIDHFHFDFGHEDHIDIFGGDHGACGHAGDEHGHFFFHHHHC>BDC@CCCD(;@?A>>CDCDDECA
@0WJ
CAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATAT
+
@???BA;B+<AD?A?FB:FDHHHGIDGI>DCHIIGGGIGCG>FFHBGBGHGCEFGCEF>FGIIIHCHAD@C?CBCCCCC:ABBABB:CCCCCC>;ADDC
@0WK
GAGGATACCTGTCTCCAGATCTCAGTAAGGTACGGAGTAACTGTCCAAAAGCCATGAAGAGATTAATGGCAGAGTGCCTCAAAAAGAAAAGAGATGAG
+
@@@DBDFD:DHFFHHGIGHIGIJJIFHEHI<CHIJCHFHGGIJGHIJHIIHEHGGGGGIIIGHIIIIGIJGGHG=AHFEF?DECBC?AC=CBDCDACC
@0WL
GCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAA
+
@@@DDDDDFHFHHIGI@;C@DAE:C<<ECD;EBHB@*?GCDHHFDGC<B>DHGE>FGIEGGGE6@DEG36AEFDEEEEA@CC@C;>?C?@;;@B?@C@CC
@0WM
GCCCATGCTGGGCCGGCGCCCTGGGGCCCCGGAGAGCAAGTGCAGCCGCGGAGCCCTGTACACAGGCTTTTCCATCCTGGTGACTCTGCTCCTCGCTGGCC
+
@@CFFFFFHHHHHJJIIJIJJJJJJJIIJJJHGFFDDEEE@CDD@CDBDDDDBDDDDDDDDEDDDDDDDDDDDEEDDDDDACDDDDDDDDDDCD>BDDDDD
@0WN
CTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGC
+
C@@FFFFFHHGHHGEHGGGHGHJIFIIIJIIIFIIIJJJIJHGGIDHIJEHHGGIJJEGIIFIJJHGHHFFFADDEDCCCDEDDCBDB<ADDDDDDDDDD
@0WO
ACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCAT
+
@@@B=DDDFHFDFGEEGFI<CIEHEFGBD0?DHGGI?D=FHIGIAH=DCHIEFEAEC?@B>@7@CE;@CCC@@@>@CCDCBB>AACA>ADBD9ACCCBDD9
@0WP
GTACCCGCCACTGAAGGGGAGCTTCCCGGAGAACCTGAGACACCTTAAGAACACCATGGAGACCATAGACTGGAAGGTCTTTGAGAGCTGGATGCACCATT
+
;??D1A:@DDDBB3E@?:<11?DD::9?:)..0*8B=)=C7.=(=A=77..=C)??D>A(.(,==A>;((,555,:8>(44444(24<A>9++48>A9244
@0WQ
CTCACCTCTCAGACAACTAAGACAGATGACCCCCAATTGAAAAGAGAAATAAGGTTAATGAAAAACAGAGAAGCTGCTCGAGAATGTCGCAGAAAGAAGA
+
CCCFFFFFHHHHHJJJJJJJJJJJJJIJJJJJJJJJJJJHGJJIGGHJJJJJJJFHJJJJJJJJJIJHHHGFFFFFFDDDDDDDDDCEDBDDDDDDCDDD
@0WR
CTCAAAGCCGTGCACGAGCAGCTTGCAGCCCTCTCTCAGCCCCAGCAGAACAAACCAAAGAAAAAGGAGAAAGACAAGAAGGAAAAGAAAAAAGAAAAGC
+
C@@FFFDDHH@?DF@FGHEGHIIIIHIGIIIIIGIIIIIIIIGIIGHGFHGGHIHHFFFFFFFEECC?BABACCCCCB<?ABBCCCCBBCCCCCBBCCCB
@0WS
CTGGATTTTTCAAAAGCAGATTCAGGTGTTCATTTATGTGTTATTGATGACTCCAATGAGCATATGCTTACTGTATGGGACTGGCAGAGGAAAGGAAAACG
+
===1<+22<AB7?@3+?<=AA<9?<A72?CABAAA>A@1?1?:1?*:AABAABBBB>==*?ABBB<AA=ABB48>AA)6>2(55=;55.56>@=(5;=>(,
@0WT
CCTCGGGTATGGTGTACCTGGCCTCCCAGCACTTTGTGCACCGAGACCTGGCCACCAGGAACTGCCTGGTTGGAGCGAATCTGCTAGTGAAGATTGGGGAC
+
C@@FFFFFGHHHFHIIIJJJJIJJIJIIJJJJJJJJFGIIIJJBHIIJJJIFHCHIIGGHHFFFFFDCDACDDCDDDBBDBCDCDDDCCCDCACDDBDDDD
@0WU
GTGGATGTTTGAATGGTTCTCTGCCTCCTGGCATAATGAGGTGTTCTGATTCCGAGGAGGCGTGGGTGCATGGGACTCTGACGTCGACCGCGGACCCCGG
+
(-0(2.@>1)9).)8))2)).)).).)()))()2)))))1).(.())0))))))0(3'('(-'',',,((((7((((,(:((,,&))&&&&)&)&&+()&
@0WV
CCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGAC
+
@@CFDFDDHHHHHJJJIJJIADHHIIIEFIJJJGIIJIGHGIJJJIHIJIIJIIIJJJJBHHGGGCHHHHHFFFEDDDBBDDDDDDEDEEECDDDDDBDDD
@0WW
CTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCC
+
@@@FFFFFGHHHHIIIDIIIJJJJIIIJIGIJJIIJJJJJJJJJJGIJJIIJGJJJJJFHFHHFEFFDFDEDDCCDDDDDDDDDDDDDDDDDDDCDCDD
@0WX
GGAAGCTTCTTTGAAGCTTGGTTTCAGAAAACCGCCGCTATTCGAATTGGGGTTCCTGAGGAGGTCTAGTATGTGGTCTGCTTCCTTTTGTCTGCTGCAGC
+
-(0((:=>??>:)).2))2;=.(<)22)))2)1(((74=;'.78)(..:)65'5(.:.=)8:(,(,:((5((,,7;;<:;((,;::(+2(22:(+85(+++
@0WY
TTTAAACTGATTGAGCCTGAAGAGGTGGCCCGACGTTGGGGCATTCAGAAAAACAGGCCAGCTATGAACTATGATAAACTTAGCCGTTCACTCCGCTATT
+
@@CDDDDD>DAFHHGGIIIHGHHHGFHGIJIIJIGHGHIJJIIJJGGEHIIIHFFEFDFDDCEDDCCDDDDDDDDDDCCDDDDDDDBD<>>ACCDDDDDD
@0WZ
CGCCTCTATTGAGCTGCTGGCCCGCTCATTGCCAAAAATTCACCGCAGTGCATCAGAACCCTCCTTGAATCGGGCTGGTTTCCAAACAGAGGATTTTAGTC
+
@@@DFDDFHHFFDHIJJGJJGHJIJGHIIJJIIIJGIJIJIJIGGIHICFIJJJJJGHHFH@DDFDEDEEDBDDDBDD?CACCDDDDDDDDDDDDDDEDAC
@0X0
CTATAGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCT
+
>=<A7,2??;32?)<)0272+??@4=@A9)):)**:?**90>*9A7*72=>=.)=)8>=;;>BA<=>>@@@@<>@9?;(5;5;>:8=',2(+8:==8:?;8
@0X1
GATGTAATCAACACCGCTTTGCCGATAGAATATGGTCCACTTGTGGAAGAGGAAGAGAAAGTGCCTGTGAGGCCCAAGGACCCTGAGGGGGTTCCTCCTCT
+
==<A2<?2,<?=CC;ACC=AABCA4?:?ABB?BAAB>BBBBBB=AAB=ABBBA=AB>AA;=)=AA@A;7;@@;=;;==========9=;=;5;;;??83;3
@0X2
GGGAAGGACGTCCTATGTACCAACGCCAGATGTCTGAGCCAAACATCCCCTTCCCACCACAAGGCTTTAAGCAGGAGTACCACGACCCAGTGTATGAACAC
+
@@CFFFFFGHFHHIJIJGHIJIEHHIJJJJGIIHFEIEHJIJJIIGGIJIIIJJJJJHHHHEFFFCEEEEEDDDDBD<:@CDD?BDDDBB@CDDDCDDCDD
@0X3
GCCCAAGCATTGCAGAAACGGCTGGCCGGGATGTGCATGTAGAATTACAGTGCTGACAGCTCCTACATGCTGGGGTAACTGGGCCAAGAGCAGATAGC
+
0(((-.:((..))))26.)2(2(88((139((0.)))))9)/)/)/3=)).)81;..))(8);03)6638(((3','(,((((((+++2(((+/(((+
@0X4
CATACCAGATAGCAGCTACCCCATGGACCACAGATTTCGCCGCCAGCTTTCTGAACCCTGTAACTCCTTTCCTCCTTTGCCGACGATGCCAAGGGAAGGAC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJIJJJJJHHHHFFFFFFFEEEEEEDDDDDDDDDDDDDDDDDDDDDDDDDDDD
@0X5
CACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCG
+
@CCFFDEDFGHHGJJJJIGGIJGIJJJJJJJIJIIIIJJJJJJJIIGHIFGIJIIGHJIJIBHIFFFHHHFFFFFCFEDDEEDCCDDDDC>@CDDDDDDD
@0X6
GAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACC
+
CCCFFFFFHGHHGIJIJIIJJIIJJJJJJIIJJJJJJJIJJJJJIJJIJIJIHHHFFFFFEEEEEEEDDDDCDDDDDDDDDDDDDDDDDDDDDEDCCCDD
@0X7
CCTGGACAACATGATCCGCCGCCTCTCCCCGGCTGAGAGAGCTCAGGGACCCAGGCCGCACCAGGAGAACAACCACCAGGAGTCCTACCCTCTGTCAGTGT
+
@@@DD<DDHHF8AF>D@?AFAEEHGGEH<F@:FG<FGH9@A2@C@=76?DBDC=;=B;?8=;<?@B?A?CCCBBBB8<8<8?9?CCCCBBCBCC:>CA4>@
@0X8
CCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTAT
+
CCCFFFFFHHHHHJJJJJIIIJJJJJJJIIJJJJHIJJIJJJJJGIJJJJJHHHFFFFFEEEEEDDDEDDDDDDDDDDDDDDDDDDEDDDDDDDDDCDDDD
@0X9
CTGGACAGTTACCTTATTCAAACATCAACAACAGGGACCAGATAATTTTTATGGTGGGACGAGGATACCTGTCTCCAGATCTCAGTAAGGTACGGAGTAAC
+
@@@FDDADDFFHHIIGIIGHDHIJJJJIIICHGIJJGHJJIIJIJJIJIJCGIGBFGIFHHGEEBDFFFEEE>CCDDDDDCDDDDACCDD>@CBB79?CC>
@0XA
CCTGGAGCGGCAATTCACTAACAAGAAAACAGGGAATTTTTGGGAAATATGAAAAGCCAAAATTTGTGCAGTGTTTAGCATTCTTGGGGAATGGAGATGTT
+
@C<DDDEDHHHGFJEEDBGIJIGIJJIJJJJFEGIIJIJJJJJECHHGEGEGIJFAHGFFFFFEECAC@@C>CCFCCA@CCCCDEDDB@B@BDDD?ACDAC
@0XB
CAGCTCACCTCCCTCCATCGCAGTTCATACCAGATAGCAGCTACCCCATGGACCACAGATTTCGCCGCCAGCTTTCTGAACCCTGTAACTCCTTTCCTCCT
+
::1ADB32CBDFD>EBFE9C?<1CEC9CF9?BFFCB?<@<B9D<9?DDDFFFIF=D9C@;C=@E=E>9>:8=AAB3>@;:A589<A@AA>ABB>@4@>ABB
@0XC
GATAATCAGCGTCCACTGCTGAAGACAGACATGGAACGTCACATCAACGAGGAGGACACAGTGCCTCTTTCTCACTTTGATGAGAGCATGGCCTACATGCC
+
@@<DDDDDDHHBFIBHHGFGCE<EDEFICIECGHDHHAFHG?DFIGHIGGIIIIIDGECAHEDEEDEECCC>CDCCCCCCCCECCCBCCCBBCBA<CCCCC
@0XD
GTGAAAATGAAAAGTTCTGTCTTTGATGAAGACAAAACTTTTGTAGCAGAAACATTGGAAATGGGTGAGGTTGTTGAAAAGGATACAACAGAACTCATGG
+
@@BDDFFFHHGFHJBGHJJJEHIJIGJIJJJEIHGIIIIJJGJFIJGHGIJJJJJJJJCDGIJJJHGHIJGEHEHHGGCHEFFFCCEEDCBCCCDDDDDD
@0XE
GAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGAC
+
@@BFFFFFFFGFDIJJJJJJJJJJJGIIJJJIJIGHIIJGGIJJIJJGHJJGHHHHFFFCEC@CEEDDCCDCBDDDDDDDDDDDDDCDDDCCCDDEDDDDD
@0XF
GCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGC
+
@@@DDB;?:<C?8CCADBGFF@9?;DBEGIGCFEGIII@@DC@FBB@F<BD=F;F@F;;DAEED?C@>A>;BBB21.;.>B>@==?:>ABB39A::@>1?
@0XG
GCTGCTATTATTTTTCTTCGTCTTTTTAGGAGGAGGTTCCTTGGCTTTGCTTTTTTTATTCTCTTCCACTTCCTCTTTCCTTTTGTGCTTTTCTTTTTTCT
+
=@??:?BD,ABFFB<<?CFFF7EFHEF3A9+?:;:C1)0:B???;*?@FFBFIFIAE@EIFF:?>E?B@>3;AAA:36;A@@ABB;?35>>3@@>3>>B9>
@0XH
GCTCAGTCTCTGAAAGATGAGATCGACGTGCTGAGACATTCTTCTGATAAAGTATCTAAACTAGAAGGTCAAGTAGAATCTTATAAAAAGAAGCTAGA
+
=<1ADD?BFBCBCEF9CAA4AIHG;?ED?EGHAGBBF<FG<9?BBD>GFFH>////8B8CGDEDC;@=.=@G>ACAC=A>BEEDECDCCABB?;;>@C
@0XI
CAGGAATCTGAATCTTGTGGTCTGCGGAAAGAAGAGAAGGAACCACATGCAGACAAAGATTTCTGCCAAGAAAAACAAGTGGCTTACTGCCCTTCTGGCA
+
?+=?B;BDDDDD4E9BCA+3<C<9+<CCAAD*?D;)?9928BD(??BEEC<4ACDD@=3@>)=3==CA>(;.;@@@52,(-5<<<:A>>AA<49<>>AA?
@0XJ
GGCTTGCAGAAGCTCAGGTACCTGACAATGATGAGCAGTTTGTACCAGACTATCAGGCTGAAAGTTTGGCTTTTCATGGCCTGCCACTGAAAATCAAGAA
+
@??DDD8BCDH;AFHEHA3<FHICHIIGBFHDB??FH>?CD>?FBD<D;B???FF??BBCGHB@@=@GGIIIIHE?)7?;BD=D@AC;>@CAC;>;>A@C
@0XK
CCGACTACAACCCCAACTACTGCTTTGCTGGCAAGACCTCCTCCATCAGTGACCTGAAGGAGGTGCCGCGGAAAAACATCACCCTCATTCGGGGGCTGGGC
+
@<@DDADDDDDHDGGBFHGBBFH@@EFC<?BDCDHBG?BDDDFDFDBFI8==BBCGIGIEED@5=?C>BBB@@BCBBA:>AC<ABB<CD>AA>@&59@><?
@0XL
TGGACAGCAGATACTTGTGCCCAGCAATCAGGTGGTCGTACAAACTGCATCAGGAGATATGCAAACATATCAGATCCGAACTACACCTTCAGCTACTTCTC
+
CCCFFFFFHHHHHJJJJIIJJJJJJJJJJJJJFHIHIIHIJJJJJJJJJJJJJHIIJJJJJIJJJIJHHGHHFFFFFFDDDDDDDDDDDDDDDDDDDDDDD
@0XM
CCGAACAGATTGTGCAAAAGAACCAAGAAATAAAAAACATGAAATTAGAGCTGACTAATTCTAAGCAAAAAGAAAGACAGTCTTCTGAAGAAATAAAAC
+
111+=8DA<+2A<2AA?FGFE3ABBG):?B?CFGFHGEF0?B9*?B*.=C>).8./8==@CGGA47?=C>;9;>A>>A??;5>555(5:@@39,5>>@3
@0XN
CTTATATGGAGCAAAACTACTGTAGAGCCCACACCTGGGAAAGGACCTAAAGGTGTATATCAAATCAGCAAACAAATCAAAGCTCATGATGGCAGTGTGTT
+
CCCFFFFFHHHHHJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJIIJJJJIIIBFGHIJJJJJJJJJJIJHHGHFFFFFEEEEEEDDDDDDDDDDCDACBD
@0XO
CTACAGTTATCCCCAGGTACCTGGGAGCTTCCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTT
+
@CCFDDDDHHHHHGIGEAIHGHIIJGIIJJJIJGHGHGHGIIJJBGFBFHBEHEHIIJIGHGIJJJIHHEEEEEFFEECEEEECDDDD?CDBDDBDDDD:A
@0XP
CTTAGCCGTTCACTCCGCTATTACTTTGAGAAAGGAATTATGCAAAAGGTGGCTGGAGAGAGATATGTCTACAAGTTTGTGTGTGATCCAGAAGCCCTTTT
+
8=?;+=A1?1DD<@CBAE1?E9<<E*:9*)):?38?9:B??*?DECDED/=BDIDD=23@@=A)?CDED:B3;@>.;@A25,,,;5(,>3:>A>A?<9<:>
@0XQ
CAGAGACAGCTTGAAGACCTTGTTGAAGAATTGAGCTTTTCAAGGGAACAGATTCAGAGAGCTAGCCAGACAATAGCTGAACAAGAAAGTAAACTTAATG
+
==++2+@<+2<?A>=<@@CB3?<A3AA7+<77:*1:ABBA417?=;)=AAA9==*?)=7>56.>.).)62;=>=A?>@>7>;>;@>=3;(;==;9==??>
@0XR
CCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATAT
+
CCCFFFFFHHHHHJJJJJJJJIIJJJJGGJJJIJGIJJGJIJGJJJJIJAHHIJJJIJHHFFDDDDDDDDDDDDDDDDCDDDEDDDDDDDDDDDDDDDDDD
@0XS
GGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATC
+
@<;BDDDDFFCDDD?EBEEGDEHIC;FBD@BD??DDHG?B>FFD=FEHIGIGHAFGIGHCEE;ACBFFCAAECBBB;=>CAC?ABC>>@CCAC@C?ABCAC
@0XT
CTCTGTTCGAGTCCCTAGAGGGCCGGCCGTGGAAGGGGGACACGTGAATATGGCATTCTCTCAGTCCAACCCTCCTTCGGAGTTGCACAAGGTCCACGGAT
+
C@CFFFFFFHFHHJIJJIJJJIJIJJJJJIIJJJIJJIJHFFFDCCDDEEEEDDDDDDEDDDDDDDDDDDDDDDDDDDDDDD?CDDDDDDDDADDDDDDBD
@0XU
TTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAAC
+
CCCFFFFFGHHHHIGGIIJIGHIJIJJJIIJIJJJJIJJJIIJJIGJIIIJIIIJIJJGHIIIIIGEDF@DEEDDDDDCDDDDDDDDDDDDCDCDD>ACDA
@0XV
AACTATGATAAACTTAGCCGTTCACTCCGCTATTACTATGAGAAAGGAATTATGCAAAAGGTGGCTGGAGAGAGATATGTCTACAAGTTTGTGTGTGATCC
+
CCCFFFFFHHHHHJJJJJJJJGJJJIJJFIGIJJJJJIJICHJIJJJJJJJJJIJJJJJJJ=FHIJJHEHEEBFCEEECCEEEDDDDCDECADCDDDDEED
@0XW
GTCGGAATGAACTCTGCTGCCCGTAGCTGCTGCTCTGTTGGCTATATTGACTTGGAGCTTGGCTGTAGGATCCAGTTTGGGGTGGGTAACTAGTGGGAGGC
+
@BCFFFFFHHHHHJJJJJJJJJIJIJJJJJJJIJJJJJJJJFHIJJJJJIJJJIIIJJJJIJGIIHIHEFEHECCDEFFDDD3;@BBDDDEDDCCDDDDDD
@0XX
CAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGAC
+
@@@DBDDBFHDBDGH;EGGICGGB@FCECHHGIIHI<<@DDDDC?D<DGH@GGGI@A;C>FCHCHGHI@ED?EE6?BC'9;=?CCCDCCC@ACA@A@:A>
@0XY
CAAAGACCTGGAGAAGATGATGGTTAAGAGGAGAGACTACTTGGACCTTGCGGCGTCCACTCCATCTGACTCCCTGATTTATGACGACGGCCTCTCAGAGG
+
@@@BB:2ACDBCDB;E@EE4ABDHFAHH9CG;F8??FDBGEFFB?F??BBFFF<BF8B@A;@CBA@@A@55:@B?ABBBDBA@>ABBBBB>BBBBAA:>A?
@0XZ
CCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTA
+
@?;ADDEACFHADCDEG?CHHGBEG?;BGDBBHFCFBDEG>98=CCCGHGHE@@DA:E4?CA;B>3=?CCCC??BB@B888?<C?>@CCCCCAC@BCACC
@0Y0
GATTAATGGCAGAGTGCCTCAAAAAGAAAAGAGATGAGAGACCACTCTTTCCCCAAATTCTCGCCTCTATTGAGCTGCTGGCCCGCTCATTGCCAAAAATT
+
;?;=BDDDDBD1A:2A+:C3+<AFEFEIIIIEDDDDDDDDDDDD@DBDEIEDEDCCADEEIEIDA<:AC;A3);;AAA@AA>???????AD>AAA>9>?>A
@0Y1
TGGAAAGTGAGTTGGCTGGGAAGCAGCATGAGATTGAAGAGCTAAACAGAGAGCTGGAAGAAATGAGGGTTACCTATGGGACTGAAGGACTGCAGCAGTT
+
@@@B?DDDFFHDFIIIIFFIIIIIGGIIIIGGIFGIFGGDGGGIIIIIHIGGGGGHIHIGIGGBGGHIH?EADFFBDDCEEECBCCCCBBCBCCCCCB>C
@0Y2
TGAATACTGCACCCAGGACCCGGATGTAATCAACACCGCTTTGCCGATAGAATATGGTCCACTTGTGGAAGAGGAAGAGAAAGTGCCTGTGAGGCCCAAGG
+
@@@D?DDDHFFDHIIGH=;EGGBA@D3C@FFGB9?FHB:D;BFCFHB8:A;AEE;@@DFC>>@CA65=35>;9<9<A?B9CCC@@CC@C>@CCB??B?AAB
@0Y3
CACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAAT
+
B@BDFFDFGGGHHJIGIIGIJJJJGHCHGFHGHGDHGGIIJJJGHIJIGIIEGHHGIIGIAAHBBCCEDDDCCCDCDDDDDDDDDCCDDDCC:@>ACCCCA
@0Y4
GAACTTTCTGTATGGGGTAAATGGATTACCTGCCACGAATGGAGGGGTACAATGACCCAGCAGCCTTCCTCCCCACCATCCAGTAGGGATTGTTGGGGGTT
+
853@())2;@).))<;(-3).<2@)).)).)1(:)1((09):)((-7--<)).)).)66(:)((693;7==7(3,',5(7;5;;(,(7+(5(566:-0&)&
@0Y5
CTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACT
+
CCCFFFFFHHHHHIJJJJJJJJJJJJIJJJJJJJJJJIJJJJJJJJJJJJJJIJHIJHHHFFFFFEEEEDD>BDDDDDDCDD>CCDDDDDDDEDDDCDDDD
@0Y6
CAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCC
+
@@@DDD?DFFHHH=CFDHGICGBEAEGCFH>;DGD@FEHAF;FBGIIIIGIGIIEEC=@>?HAA;@D?B3>BCCBBCA@A@A@@C:@@CCCCC>>CC?BB@
@0Y7
TACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTT
+
@?@FDDEFHHHHHEHGAEHGGIBHGIIIIIIIIIIIIGGIGIIGIEHIIGGHGDHHEHHHIIIIIEHHHHHFFFFCACCDEEDDCDCCCDDD@==@DDCE
@0Y8
CGAAACCTGACCGGGCCTTCCCAGCTCACCTCCCTCCATCGCAGTCCATACCAGATAGCAGCTACCCCATGGACCACAGATTTCGCCGCCAGCTTTCTGA
+
C@CDDFFFFDHAHGGIGGIGCGDHEII<GIGIIIHGIJGHJCEHFHIGEGGGBEEEHDDCFFC@CEEDD?=?AADDDDDCDDDD9<<9@@BDB@CCCCDD
@0Y9
CAGCCCCAGCAGAACAAACCAAAGAAAAAGGAGAAAGACAAGAAGGAAAAGAAAAAAGAAAAGCACAAAAGGAAAGAGGAAGTGGAAGAGAATAAAAAA
+
@CCFFFFDHHHGHIGIJJJJIJFIJJJEGIIJIGIEGIGIIGCHIIJJIJJJIIIIHFDEDECCECEDBDCBBDDDCCDDD@@ACDDA?ACDDDDDDDD
@0YA
CATTGCCAAAAATTCACCGCAGTGCATCAGAACCCTCCTTGAATCGGGCTGGTTTCCAAACAGAGGATTTTAGTCTATATGCTTGTGCTTCTCCAAAAAC
+
CCCFFFFFHHHHHJIJJJJJJJHIJJJJJJJJJJJJJJJJJJJJJJJJJIJJEHIIJHHHHHFFFFEEEEEEDCDEDEFEEDEEDADDDDDDDDDDDDDD
@0YB
AGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACC
+
CCCFFFFFHHHFHIJJJJJJIIJJJJIJJJJJIIIJIJJIJJIJ@GHIJJJJHFHHHHFFFFDDCEEECDDD?BDDDDDDDDDDCDDDDDDDDDDDCDDDD
@0YC
TCAGAGTGTGGGATTCTGTTACTCTATCCACACTGCAGATTATTGGACTTGGCACTTTTGAGCGTGGAGTAGGATGCCTGGATTTTTCAAAAGCAGATTC
+
BCCFFFBDFHHGHJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJIJJJJJFJJJJJJIGIJJHIJGHEHHHFFFFFEEDACEDDDDDDDDDDDDDDDD
@0YD
CTTTAGCAGTGCCCTGGGAAGGCTCTTCAGGAGCCATGTGGGGAGATGACAGAGGTACCCCCATGGCTCAGAGTTATGATCAGAATCCTTCCCCTAGAGC
+
@@@BBD4B:2A<:C:CAD>F?C9EFEED*1*CGG<@>?0?<@F16'=C@B==;CE=CEEE?EDBB?@@(;@BB5;@A3;>:;AA>(,5,53:@BB?@BBB
@0YE
CCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGT
+
C@CFFDFFFFFFHIEHIIIJHGIJJJJJJHIJJJIIJJIIIJJGHIJIIJIJH?EHHEFFFFDFDEEEEDDBDCCCCCCBD?BDDDDDDDDDDDDDDDBDC
@0YF
ATTGCAGCTTGCCAGGACCTTTGAGGGCCAACAGCCCACCCTTGAGGTCCAAAGAAAATCAAGAACAGAGCTGTGAAACCGTAGGGCATCCCAGTGATCTG
+
@<@DDDDDHDBFHIIIGBHHGG<E=GIIIIHFIIIIIII<FHGHHID=DHHCFHGHIEEIB=CHHCEDC@CAC3>CDCCB;5<?@BC?CCCBCCCCACDDC
@0YG
CTCCTACATGCCTTCCTACCATGCCCACCAGCAGAAGGTGAACTTTGTCCCTCCCCATCCATCCTCCATGCCTGTCACTTCCTCCAGCTTCTTTGGGGCCG
+
+1144AD;D?CADEEIEEECFI4?ABCAEFIDE;B@?DDB4DBBBDDE?409??;;@8@=AAC@@@C;A33==>@@A7?D;>66;@AAAA33>AAA'3200
@0YH
GATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCC
+
C@CFFFFFHHHHHJJJJJJJJJJJJJIJJJJJJJJJJJJJJJGIJJJJJJIJJJJJIIJJIHAEHHHFFFF@EFEEEDDDDDDDDCDDDDCDDDDDBDDDD
@0YI
CAGAAGGCTGTATGTTTGAAAAGGGCCCCAGGCAGTTTTATGATGACACCTGTGTTGTCCCAGAAAAATTCGATGGAGACATCAAACAAGAGCCAGGAATG
+
@@7BDBDDDFDFFEBEFG:CIFBFGFDEEFGFCFEIIFII<GAFFG@FBFBFFC=FEFF@FEEFFFFEE?3?77BC>@;@BA@BBA39?B9<BBB?@BB>@
@0YJ
CAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCT
+
<??BB8?DF<FHHGHHIHBCFHB9AFFHIGDHGGGG3*BB@BF;B9D<B>@>FH86@@-=/?DEEEEEC@CCCCBCB>C@:CDCCCACCC:@BB?CAC<?
@0YK
ATCACTTCATCTCTGGCAGTTTTTGGTAGCTCTTCTGGATGACCCTTCAAATTCTCATTTTATTGCCTGGACTGGTCGAGGCATGGAATTTAAACTGATTG
+
1:?D?DDAB,ADD>EEE9A:<CCC1?FEE@?CCEE9:3:<?*0?BDCBDEIC@D>DDDCECBEI<CEICC@=CCCDCA59???>?=;>:AAAD>A::A:A3
@0YL
TGATTATTTGTCTTGTTTTGTTGTTTTTGTTTTGTTTTTTTAATCTTCTAGAAAGGAATGTTTTTGATTTTGGTTCTCCAATTTAGTCCATTTTATTGCT
+
@@@DD;BBFDD?AHHFGHHIFBHCGFGGIIIIGIIIIIIIEE9BGGHDH8CHHIHCHIIA?CEEHE?@CCCCCC?>@>;@CACC@>AAC>BDDDDC:>CC
@0YM
GGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCATATGCAACTTCTT
+
;7+AD=3A;AD8<<BFF<A3CBFHIF9B3?BEFGFFD?G>GEFEFE@A4989??CFEBF@@@@E=ADEE;AC;B;?BBB@/=@BB@',(,;:(449@3>A
@0YN
GGGCTTCTCGTCCTCAGAGTCGGAGAGCTCCAGTGAGTCCAGCTCCTCTGACAGCGAAGACTCCGAAACAGCATCTGCATTGCCGGGACCGGATATGAGC
+
@@@DA?;BFDFDF7BCEDC3:CF?E8CCFFEEI4B9BB@CFFDAF<=BAFF>FIFFBBB8?;???@B@6?@??>@AA>A>>BB@BBBBB8@B@<@>A:>@
@0YO
CAAAAGGAAAGAGGAAGTGGAAGAGAATAAAAAAAGCAAAGCCAAGGAACCTCCTCCTAAAAAGACGAAGAAAAATAATAGCAGCAACAGCAATGTGAGC
+
?@;D;?DBDBAAC@EBHCFGHDBA<EED>DCFHEGG>GGGII@F>BAGE>GA;CDECACCC@D>;AC;?=;ACC?5>CDA@CC@@??BBB??CCC>CCC>
@0YP
CTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTT
+
CCCFFFFFHGHFFJFJJJIIIJJJGIGIIGGIJI<<DHIJGGIFIIFIJGIIFIJIBHGGIHAEEHHFFFECEDDDDDDDDDDDDDDDCCCDADDDD39>B
@0YQ
CAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATAT
+
CCCFFFFFHHHHHJJJJIJJJJJJJHJJJJJJJJJJJJJIJJJJJJJJJJJJJIJJJJJJJJJJHHHHFFFFFFEEECEDDDDDDCCDDDDDCDEDEEC
@0YR
GTGTTCACACTTTGTCAGATGAGAAATGGGATGTTATTAACTGGAGGAGGGAAAGACAGAAAAATAATTCTGTGGGATCATGATCTGAATCCTGAAAG
+
@C@FD>DAFBFFBIFGII4AE@FDHGHGIBG>G?BC<CF9FGG;9B;6BGADDGB8=FFEGEEHGGIE>EEHAACB?C?>;;@>>AC;;A@CCCACCC
@0YS
GGATACAACAGAACTCATGGAAAAACTTGAGGTAACCAAGCGAGAGAAATTAGAGCTGTCACAGAGACTGTCTGATCTTTCTGAACAATTGAAACAGAAAC
+
CCCFFFFFHGHGHJJJJJIJJJJJJIJJJIJJFHIJJJIJGHFHIIHIJGIJIIJJJIHGHGJJIIHEEHHFFFFECEEEEEDEECDDDDDDDDDDDDDDD
@0YT
ATGGAACAAGAAACACAAAGAAAGTTAGAACAACTCCGGGCAGAGCTGGATGAGATGTATGGGCAGCAGATAGTGCAAATGAAACAAGAATTAATAAGAC
+
@@@?=DDDFDH;DFG?FGDFHIBCFEC4CGHII;<??FDD:FE=8=BCC@FCAAF@C=DCEE2;?>?@DCCCC>>ACCCCC>>@@CBCC?CCCCAC>@CC
@0YU
CACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGC
+
=?;ADB?A?D::C:2A2<<F@?AD@2<F9???<11?:*?DB?D?8@D:C8=C<C;)>C8777).@7?DDC7;;7);666(66((;A(((,,8,(,&&09(+
@0YV
ATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCA
+
?@@BDEDDHHHFDCE>GBIEE@<CHCHGIICFBAHIDHIIIFGGCB;;BDFFFHIII@@CFDHEECEA4;?@;>;>;6@C@-;>;>?A?(<3>CA3>:>A
@0YW
GCCCCCTCCCACGTATGAGTCGGAGGAAGAGGACAAGTGCAAGCCTATGTCCTATGAGGAGAAGCGGCAGCTCAGCTTGGACATCAACAAGCTCCCCGGCG
+
<@@FDD>DHFHHFIDGG>BHBFGIGEGG@AHHHGGIGFDGHIH2@FGIGEDGGIIFEHFC;=B@BBA@BB@CCDDDDDDDCCDCCCCCDD?BCCDDDD@DB
@0YX
CAGAAGTCATCAGAATGCAAGATAAAAATCCATACAGCTTTCAGTCAGATGTATATGCATTTGGAATTGTTCTGTATGAATTGATGACTGGACAGTTACCT
+
@@@=?DEDHHAFDIIGE>FDDEHCHIDFHDAHE<CCE?EFH@BFDDGGHGGDHGEIDHDFHGCGCEHIGGHIDGGE@EGEEHEGGCE>AEH@@DBACE>AC
@0YY
GTACAAGTACCCTTCTGACATCTCCTACATGCCTTCCTACCATGCCCACCAGCAGAAGGTGAACTTTGTCCCTCCCCATCCATCCTCCATGCCTGTCACTT
+
CCCFFFFDHHHHGIJJJGIIJJJJIHJJIJIJGGIIJIJIJJJJJJIJJJIJJJIGHIJBFGGIHIIGDHIJIHHHGFFFFECECCEDDDCDDDDDDDDDD
@0YZ
GCAGGAGTACCACGACCCAGTGTATGAACACAACACCATGGTTGGCAGTGCGGCCAGCCAAAGCTTTCCCCCTCCTCTGATGATTAAACAGGAACCCAG
+
CCCFFFFFHHHHHJJJJJJJHIGJJJJJJJIIJJJJJJJJJGIJJJJJIJJJJHHFFFDEEEDDDDDDDDDDDDDDDDDDEDEEEDDDDDDDDDDDDDD
@0Z0
CTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTT
+
@CCFFFFFHHHHHJIIJIEHHIJJJJJIIIJJJJJJFIJIJJJJJIGGHGIIHIIIIIIEHIJEEFFFDEEEEDDDDDDDDDDDDDDBBD?CDDDDDDDCD
@0Z1
GGGGGACGTGTTAGATTTTATTTCTCAGTGCATGGTATGAACCAAAGGCACTAGCAAAACCACGGTGCATCGTAGCTGGAGAAGAGATAGATGGGTGACCG
+
((((((((0(2()).2)2)2)):))2)).)26?.2.0976):(((())((..)))/)))(-(-(-(('..('.(((((,,8:(((,((,:5(8((()2:2&
@0Z2
TGAAAATCAAGAAAGAACCCCACAGTCCATGTTCAGAAATCAGCTCTGCCTGCAGTCAAGAACAGCCCTTTAAATTCAGCTATGGAGACAAGTGCCTGTAC
+
:1?;=ADDDF8DC;<222383+@<;??EEFB*1**11?99?<DB*B?*9?/8B9C).88B47@;)6CE>=7==)?@3).?76(;A:6((,(,5,,>:(,;>
@0Z3
CTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCT
+
CCCFFFFFHHHHHJIJJJJJIJJJIJJJJJJJJIJJIJIJJJFHIJJJJJEGGHIJIIJJJGHHCFEEFECDDEDDDDCDEDDDDDBDDBDDDDDDDCDCC
@0Z4
TACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCT
+
?<@AAA8D?+AFFIEBFFIII;1:?D@FF*B?9FCD;?9?FDFC@FBFII;@>??A9)...73.66;>>;(-,;;:A@::5>>;@(,4:(8<?@BBB@@B4
@0Z5
GCCCAACTTTGCCATCATTTTGGAGAGGATTGAATACTGCACCCAGGACCCGGATGTAATCAACACCGCTTTGCCGATAGAATATGGTCCACTTGTGGA
+
CCCFFFFFHHHHHJJGHIJJJIJCGGIGGICHIIJJJJGJJJJJIJICHIIIIIJJJIJHHHHGGFFFDADDDDDDDDBBDDDDDDD@CDCAACCCCD@
@0Z6
GGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGC
+
@@@DDDD??C:?FHGBF>HHIIIG>G<@@GIDBH>FHECAFFHIIGBAHHEHHE7AEEHCCEBD<>BB?BBB<??BCC>>:?3@>CCDCCCCBBCBBBBBB
@0Z7
CTGTTGCACCGCTCCAGGTCACCTATCACGACAAATCACCGGCCTTCTCCTGACCCCGAGCAGCGGCCCCTCCGGTCCCCCCTGGACAACATGATCCGCCG
+
@@CDDFFFHGHHFIIIJJEHHIJGGIJIIJJJIIJG>GIJGHHJJJJEHIJFEHHHFFDDDDCDBDBDDDDDDDBBDDDBDDDDDBDDDBDDDDCDDDDD9
@0Z8
CCTCCTCCTAAAAAGACGAAGAAAAATAATAGCAGCAACAGCAATGTGAGCAAGAAGGAGCCAGCGCCCATGAAGAGCAAGCCCCCTCCCACGTATGAGTC
+
@@@DFDEFHHD?BF<;FGGIEGGHEGDHIGFHGEGGED;DHGCG@HFEGIDEBFHIGHE9EHHECFEC>8A?CAC@A9@C<?BB9BBCC@?AB<A:A:A:A
@0Z9
GCAAGTCCAGGCACAGATGGAGTACAGGGACTTCAGACATTAACCATGACAAATTCAGGCAGTACTCAGCAAGGTACAACTATTCTTCAGTATGCACAGAC
+
;8=DD:ABFB;DFBGDH9AB?C:CEHGHC=D@DDDF>GGB@GI@F@DGD>?</?D9CHD>F;==7@@CACHIFA)7=?@7@DBCC@AADC;ACCCDCC??<
@0ZA
CTGACACAGAAGCTCTTTCCTGTTTTCTTATCCCAGTGCTTCGTTCCCTGGCCCGGCTGAAGCCCACTATGACCCTGGAGGAGGGACTGCCATTGGCTGTG
+
CCCFDFFDHHFGHIEGHGEE<HEHIIIIIIIIGIIIHHHIIIIGGIIIIIIIIGHIGIIGIHHHHHFFFFFDCEBEDD=BD?BDDBBBDCDDDDDDCDD2?
@0ZB
CTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTC
+
@@@DDDDDBDFFFIA4CB;FE;:C+++111::4???C1CFBBG;GDFA>/?D8B)=AF=F=8@=EBCC>A7??<@?89:3:>@>A5>A>>:A:(:4(8<(9
@0ZC
ACTGGAGCAGGGATGACGTAGCCCAGTGGCTCAAGTGGGCTGAAAATGAGTTTTCTTTAAGGCCAATTGACAGCAACACGTTTGAAATGAATGGCAAAGCT
+
CCCFFFFFHHHHGJJJJJJJIJJJJJIJIJJJJJJGHJJJIJJJJJJJIJHGIJJJJJIIJJIJJHHHHHFFFFFEEEDDDDDDDDDDDDDEDDDDDDDDD
@0ZD
CACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAAT
+
CCCFFFFFHDFFHHJHIJJJJJJJJJJJEIGIIJGJJJJJIIIDIIGIIEGHIIGIJJJJJHHFFCEEDEDCDDDD@<B?@BDCDDDCDDACCCDDCDDDD
@0ZE
TACTCAAGTAAGCTCTTTATTAGATGGAGTTGTGACTATGACAAGCAGGGGTGCTGAAGGATCAGTTTCTAAAGTAAATAAAAGTTTTGGTGAAGAATCA
+
?@@DDDDD:C:<<A@FFHCFH<A<CEGAHAE>FGG?EFGG@>BEGEGBDBD?FHIG:7@@=E@@@EGH=?=AAC;?@C>>@CCCCCEC?@@?::>5:ACC
@0ZF
CTCAAAGCCGTGCACGAGCAGCTTGCAGCCCTCTCTCAGCCCCAGCAGAACAAACCAAAGAAAAAGGAGAAAGACAAGAAGGAAAAGAAAAAAGAAAAGC
+
CCCFFFFFGHHHHJJJJIJJJJJJJIJJJJJJJJJJJJJJJJJJJJJIJJJJJJHHHHFFFFFEEDD@BADDDDDDDDDDDDDDDDDBDDDDDDDDDDDC
@0ZG
ACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCT
+
@@@FDFDFHHDDHBFHHIEHGGIG:FHHIIIIIIIIIIIAGEDFGEHIGGEFHIAGHHHIIGGHIGHGHFHEDDCCC:BCBCCCCCC:ABBCBCBCCCC@
@0ZH
GGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACAC
+
CCCFFFFFHHHHHJJJJIJJJJJJJJJJHHJJJJJIIJJJJJJJJJJJJJJJIJJJJJJJJIIJJJJIHHHHHFFFFFDDECDDDDDDCDDCDDDDCDDD
@0ZI
CACAGCTTCTATTTAGTCACGAAGAAGAGCTTTCCAAACTGAAGGAAGATTTAGAAATTGAACATCGAATAAATATTGAAAAACTTAAAGATAATTTAGGC
+
CCCFFFFFHHHHHJJJHIJJJJJJJJJJIJIJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJIJJJJIJHHHHHHGFFFFFDEEEEDDDDDDDFEDCDD
@0ZJ
GCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATG
+
@@<ADDFFHDHFHIIIIIIGIIIIIEGGGGIEFGGHIIHBCHGHIGEGIIIA8EEFGIIIHGEEC;@CFFDECED;ACDCDCDDCCCDDDDD?ACCBACCD
@0ZK
CCAGGACCTCAGCGAGAAAGGAAGTCATCTTCATCCTCAGAAGACAGGAATCGAATGAAAACACTTGGTAGACGGGACTCGAGTGATGATTGGGAGATTCC
+
CCCFFFFFGHHHGJJJIJFIIJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJIJJHHHHEHFFFFDDDDDDDDD@ACEDDDFCDDDDDDDDE
@0ZL
CGGAGGAAGAGGACAAGTGCAAGCCTATGTCCTATGAGGAGAAGCGGCAGCTCAGCTTGGACATCAACAAGCTCCCCGGCGAGAAGCTGGGCCGCGTGGTG
+
@@@DDFFFGHHHHIIIHBEGIJJIJJIJJIIJIJIJGJJIIJIGIJJJIJIIIHGHHGFDC@CCCEEEEDDDDDDDDDBDBBBBDDCDDCDBBBBDBBD<?
@0ZM
CTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCT
+
CC@FFFDFH?CFHIIIIIIGGIIEHGBGGGIGIIIIDHIIIGIIIAHHIGCBHIIGCFC@GAADEHIFCC>ABEDDDDDCDCDA@DCDDDDDDDA@CDCDC
@0ZN
GTCGGAGAGCTCCAGTGAGTCCAGCTCCTCTGACAGCGAAGACTCCGAAACAGCATCTGCATTGCCGGGACCGGATATGAGCATGAAACCTAGTGCCGCCC
+
??;DDADD+2<CDEE:EEIII@DEEIII;CBADADA;?6)0?BE9BDAD@-@3(=CA;?).;;777>@>8;?:>&)5>AA:A+4>>:4>>9:4+(+>9059
@0ZO
CTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTC
+
@C@FDDDDHDDFFEGGHIIAH@FDABEHIIIG?CGHGGGGIEHBFHEGGIG>GEGGGHFG@GHDEEHFEHFEDCC@CEC;A=CCCC>>BBC<8>@CC?:4@
@0ZP
CGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCT
+
@;@DBD?DF?AA32<<A<AABF+22A9<2C<1CB?1:C;;BF9DB>9?B?FF:F=(=F38@;7CEAE;7?E>BD?DCCB==;@BB>3>?:A>5(,88?<?+
@0ZQ
GCACAGATGGAGGAAATGAAAACACGGCATAAGGGAGAAATGGAGAATGCTTTAAGGTCATATTCAAATATTACAGTTAATGAAGATCAGATAAAGTTAAT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJIJIJJJJJJJJJJJGHIJJJHHHHHHHFFFFFFFEEEEEEDDCDDDDDDDDDDDDEEE
@0ZR
CAGCGTCCACTGCTGAAGACAGACATGGAACGTCACATCAACGAGGAGGACACAGTGCCTCTTTCTCACTTTGATGAGAGCATGGCCTACATGCCGGAAGG
+
@@@DFFFFHFHHHJJIGIJJJJIJIJJJIJJIIIIJJJIIIJIHIJHIIGHIIJJJJGHHHHHFBCDC@CEEEEECC>CDDDDCDDDD>CDDCDDDDBDDD
@0ZS
CCTGCAGTGTACCGCCGGAAGCACCAGGAGCTGCAAGCCATGCAGATGGAGCTGCAGAGCCCTGAGTACAAGCTGAGCAAGCTCCGCACCTCGACCATCAT
+
CCCFFFFFHHHHHJIJJJIJIJJJJJJJIJJIJJIJIIJJJGIHHIIJIJHHHHHFFFFFEDDDCDDCDDDDDDDDDDDDCDCDDBB>BDABDDDDDDDCD
@0ZT
GGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAAT
+
@@CFDFDFHDHFHIJJIJIHEHIIIJJJJJIJJJIJIIIGCHJIIFIDHGI@HIGIIIGJJJIEIHHGFFEEFEC@C>C@A>CC<?ABDCDDCCC>CDDE
@0ZU
CAGCGAGAAAGGAAGTCATCTTCATCCTCAGAAGACAGGAATCGAATGAAAACACTTGGTAGACGGGACTCGAGTGATGATTGGGAGATTCCTGATGGGC
+
@@@FFFFDDHHGDGBHIIGGHHH<EHFHIDGGIJGHBDGGHIIGIJIIGIHABEGIGJJ;FG@GGAEE<;;A6>6?>CC@BCCBDBBBDCADDDAACDB?
@0ZV
GGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATC
+
CCCFFDFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJHIJJJJJJJJJJJJJJJJJJEHHHHHHFFFDEEEEDDDDDDDDDDDDDDDDDDDDDDDDDDDD
@0ZW
CATCACTTAGAGCAACTCAACCAAGTGAAAATGATAAACTTCAGAAAGAACTCAATGTACTTAAATCAGAACAGGACTTGATTAGAGACCAAGGATTTCGT
+
?<@AD?4:=?A<CG9EEECE;+:ACCFAH>?EF@*:CG@GC>A*BFADAFB9*?;DF?F*8B=CFEEE@@@CEDC9(=?C=CBD3?>3>BCC21=B((>3<
@0ZX
CAGCAGATGACTGCAGTTCAGAGGTAAATGGTTGCAGTTTTGTGATGAGAACAGGAAAGCCTACAAATTTATTAAGGGAAGAAGAATTTGGTGTTGATGAT
+
@CCFFFFFHGHGHIIIHHIJJJIGHHHJJIIFHGIJJJIIJIFGHIIEHIJCIIJJJJFJIIJJIJJEGIIIJIJEEHEFFDDFCEEDECCB??BDDDCDF
@0ZY
GCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCC
+
CCCFFFFFHHHHHIIEIJJHHGHIJJGIHIJIJIJJEGIJJJIIGIIJJJJIIGIJJIJJIEHHAGHIGFHHFFFDDCDDDDCDDCDDDDCDDDDDBACC
@0ZZ
GTTTGATTCATCAAAGGCAAATTTTGCAAAAATAACAAGGACAGAAAACCTCCATGTTTCTCATATCTTGCAAAAAGCAAAAATTGAAGTCAGAGAAGATG
+
;;?DDD,=AFDBFGF><AFFHGGIFHDHIIG9:?FEFEIC)?B?:???DFIGEF@@BAHGBEH@F@G;>@@EHIIF5AHEEEB(6@CCA5;;A(-5-9?5>
@100
TACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTC
+
=???DDAB>DD>?E>EED:FFII71?DD<>DB?BABB<*?0B3BD;;CD;=(==C@AADD>C@(;;@A96;6;(5>A?=>A>::5>??<8><>:44:>>
@101
CTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGC
+
@;@BDDD?CDFA?CF4EHGIIH@HGIGGEH>EHDCEBDGB@ADB?D9?B9DD;DF@C(==D((==6@GH=;;CCE9BBCC:;>?8@=:@B>>@CCC?CB?B
@102
AACTGGTCCCCATTGTGCCCCTGGAAAAAGCTTGGCCAGGGCCACATGGGACAACCGGGGAAGGAGGTCCTGTGGCCACTCTATCCAAGCCTTCCCTAGGT
+
;==?13A+<CC3=C+2,+A=C?;=;C@@A85@7:A;?;ABA)=AA=A=>A)5;=A;-4=939;((52=(:=?(:=1+(++8;?78;;=?72(43(((5383
@103
AGAAAAGTAGTTTGTTGGCAGAGAATCAGGTATTAATGGAAAGACTCAATCAATCTGATTCTATAGAAGACCCTAACAGTCCAGCAGGAAGAAGGCATTTG
+
CC@FFFFBFHHGFHHBHGDIIIJJJJJJJICGGIIJGJHIIJJJJIGIIGGHIGIIJJJIIIGIJCHJJGIJJJIJHHHFEFFFCFEDDDBDDCDDDDDDE
@104
TGGACAACATGATCCGCCGCCTCTCCCCGGCTGAGAGAGCTCAGGGACCCAGGCCGCACCAGGAGAACAACCACCAGGAGTCCTACCCTCTGTCAGTGTCT
+
CCCFFFFFHHHHHJJJJIHIIIJEIIJJJJJIJIJIJJJJJJJJJHHHFFFFCDD?@BD@BDDDDDDCDCDDDDDDDDDDACCCCDDDCBCC>CCDCCCD(
@105
TGCATCTCCAAACTCAACTCATACACCGAAACCTGACCGGGCCTTCCCAGCTCACCTCCCTCCATCGCAGTCCATACCAGATAGCAGCTACCCCATGGACC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJIIJJJJIHHHHHGFFFFEDEEEDDDDDDDDEDDDDDDDDDDDDDDDDDDDBCDDDDD
@106
CATGAAGACCTCACAGTAAAAATAGGTGATTTTGGTCTAGCTACAGTGAAATCTCGATGGAGTGGGTCCCATCAGTTTGAACAGTTGTCTGGATCCATTTT
+
@B@FFFFFHHHFHIJJHJIIJIIGJJFGFHJIJIIGIIIGIIJJJJFGIJJIJGHJJIIGCGGFHHGGGJJJHFFHHHFEFFFFEEDCEEDDDDDDDDEED
@107
CACCAGGAGTCCTACCCTCTGTCAGTGTCTCCCATGGAGAATAATCACTGCCCAGCGTCCTCCGAGTCCCACCCGAAGCCATCCAGCCCCCGGCAGGAG
+
CC@FFFFDDHGFDHIEBDFFEBHDFFFCHAGGIGHIIIIJGCCHA?BGEGHIJ9DFAFGBFGGGB<?CEC@EAA<BD6=??ACBDACBDDDBDD>BD@B
@108
GACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACCCCAACTGCCCCCCAGGCATACAGCCAGCCTG
+
;@@BBDDDDBF<DBD><EAFD:;FGG>HH:DG9DDGCH?B<FCGGGGC(8==;@;@DGC9AHA7?;7@;).;;?BCA>?<?B<@?<<AC>CC(481<<?A?
@109
GGAGCCTTTCTGGGTTGGGGAGAGGAAAGGAAAGTGGAAAAAACCTGAGAACTTCCTGATCTCTCTCGCTGTGAGACATGTCTGAGACTCCTGCTCAGTGT
+
CC@DFDDFFFCDFB<EFA@ECFECC;B?B?:BDB9B@FEEGHA@GID>AD@AAECAA;?CEFC>C@C?B=>8>@@ACCCCEDEC>@>CCDCDCC:>@A>>>
@10A
CTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCC
+
BC@DFFFFHHBHGIGHFEHIIIIJIJIJJIJJJJJIJIIJJJJEBFHIJJJJJIJCHHIFHHHHEDFFFFEEEEDDDDDBDBDCDDDDDBBBDDDDDDD
@10B
GACATCTCCTGTGACTCTCACCTCTCAGACAACTAAGACAGATGACCCCCAATTGAAAAGAGAAATAAGGTTAATGAAAAACAGAGAAGCTGCTCGAGAAT
+
;:1A?7+<22=CCB9B7+3>=@>A3=2>?A==5?AA<B7?:A<=AA*08.=<A>>>AB>>;7)7777.>A7>;A@?@@@@@';>;;=5;?(5(,,;2=<;;
@10C
GGACTTTCGCTATCGATCTCCTCATTCAGGTGATGTGCTCTATGAACTCCTTCAGCATATTCTGAAGCAGAGGAAACCTCGGATTCTTTTTTCACCATTCT
+
<@@FDFFD?FH=FII?BGGCH@CHE<BFH@??B4?1?99DHHDADFGEA<FHIDFHB=<BFGA=;F>DG@;=CEEEE>CEDE9=;CDEDDDDCCDD@CCBC
@10D
GTCATGCTGGGGTGCTGGCAGAGGGAACCACAGCAGCGGTTGAACATCAAGGAGATCTACAAAATCCTCCATGCTTTGGGGAAGGCCACCC
+
=:=DDBDD?:DH@1A<:<C@+@F?::F?D>FD>FB8DGBFA/=@DCE@;C)7A=B@??CD@CAB:;A@>?CA3>CDC5,''+022<@BB?9
@10E
CTAGCTGCCACTCCATTTATATGAGGCAAGAAGGCTTCCTGGCTCATCCCAGCAGAACAGAAGGCTGTATGTTTGAAAAGGGCCCCAGGCAGTTTTATGAT
+
@@@DD;DDHHDBAFFGIIDH?HF<FGHEAEHG@FHHDHEH@FD@FABBDCF?D??CF;CHGE)@DDHAH:C?7AHDCDDEBC;?;>BBB?A@(:CCCCCCD
@10F
CTTTCTGGGTTGGGGAGAGGAAAGGAAAGTGGAAAAAACCTGAGAACTTCCTGATCTCTCTCGCTGTGAGACATGTCTGAGACTCCTGCTCAGTGTAGCAT
+
@BCFDEFFHHHFHIGGGGGHEGIGHIJJJFGIJIJGIJJJJIIGHIGJIIJJHEHCEHFFFFDDDCBDEDCDDDCEDDDDDCDCDDDDDCDDDDDEEDDDE
@10G
CCACTGCACCTACACGACAGCAGGATGGAAACAAGCCCACTGAGGCTAGTCAACCTCAATCGAGCACAGGGGGGTAAAACCAGCCCAACCTAGGATATGG
+
(0(8()))28111=)-85(2(2=(@3:16)8=?()0<<>1()<1((7.()):33(.;>)63(.9;==97((3/&&0(5:2(+(+((2(+&+(8626/:64
@10H
TTGGTGTTGATGATTCTTATTCTGAACAAGGAGCACAAGACAGTCCGACTCATCTAGAGATGATGGAAAGTGAGTTGGCTGGGAAGCAGCATGAGATTGA
+
B@CFDDFFHHHHHJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJIJJJJJJIJIJFGIIIIIGIGHAEHHFFFFFEDDDDDBDDDBBDDDDDDDDD
@10I
GCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGAATGCCACTGGTGCTTATGATACCACCACTGCTACAGTC
+
:?@DD?;DBDDHFFEA2:CEEEHH<EGCD@1CFGHH=@?DDG=B<B8.=FHHD@EACE><D'9@;((6@3;=-5>(,5>:5@CCC:@???C>A4>4>+::
@10J
CCTAACAGTCCAGCAGGAAGAAGGCATTTGCAGCTCCAGACTCAATTAGAACAGCTCCAAGAAGAAACATTCAGACTAGAAGCAGCCAAAGATGATTATCG
+
CCCFFFFFHGHHHJJJJJJJJJJJIJJJJJJJJJIJJIJJJIJJJJJJJJJJIIJJJJJJIJJJJJJJJHHHHHHHFFFFFDEDEEDDDDCCDDDEFEDDD
@10K
GTTGCACCGCTCCAGGTCACCTATCACGACAAATCACCGGCCTTCTCCTGACCCCGAGCAGCGGCCCCTCCGGTCCCCCCTGGACAACATGATCCGCCGCC
+
CCCFFFFFHGHHGJJJIHIJJJJJJJJJJJJHHHIJJJIIGIJJIGIJJIIHHHHFDDDDDD@@BDDDBBDBBBBDDDDDDDDBDCD?BDCDCCCABDDDD
@10L
CTGCTGGAGCTCATGGCGGGGGGGGACCCCCAATCCCTCCTCCCCGAGACCCCCCCCCGCCCCGGCCACCCCCCCCCCCCCGCCCTTCTGGGCCCTCTGC
+
@@@FFFFF?FHHHGGGGGI@AD@-5&&2((&&++88(338(8>()&0&)&+8(07@5<&&5<&&&&0&(()5009-5<B9-)&0)&(+((+(2<0((3(+
@10M
CCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATAC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJIJJJJJJJJJIJJIJJJJJJIJJJJJFGDGIHHHHFFFFEECEEEEDEDDDDDDDDCDDDDDDDDBDDDDDD
@10N
CAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATAT
+
CCCFFFFFHHHHHJJJJIIHIJJJIDHGIJJHIJJJJJJGGIJJJJJJJJIJIEHIIJGHJGIJEHHHFFFEDFDECECCDD@CBD>CCACCACDDEED
@10O
CTCCTCTCCTGGTCTCTCAACAGGCAAAACGGGAGGAGGAGCGCAGCCCAGCTGCCCCACCACCTCTGCCTACCACCTCCTCTGGCAAGGCTGCAAAGAA
+
@;?D?DAADBFHAFFGIIIIGGIIGGICFHCHEHEDFA@F@B;BFFAHHHFHCB@D=AABBBB@?@:(>CCCCBCCB8?B?C3>@CCA?88@<BCCCCCB
@10P
GGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGC
+
?@@DDFFFF?DDHEHHIIICHCHG;DGCECCHGDDD@HBGEGDD9DFGEHHGGBFGE:D@@DEFCHFBE??>C@>>>5>AC>C@CCCCCAB@BCCCCCB
@10Q
CAGAGAGCTAGACAGACAATAGCTGAACAAGAAAGTAAACTTAATGAAGCACATAAGTCCCTTAGTACAGTGGAAGATTTGAAAGCTGAGATTGTTTCTGC
+
@@@DFFFFDHHDFFA@BFHGHBGGCCFGHEGHIGI19DGIIIIEGBF>?FEFDCDHG0BGGHIAF=CFHD=CC;@@A>EEHGBE@7?D>=>@CC5@AC>AC
@10R
GGGAGATGACAGAGGTACCCCCATGGCTCAGAGTTATGATCAGAATCCTTCCCCTAGAGCAGCTGGGGAGAGGGACGATGTCTGTCTCAGCCCAGGAGTTT
+
@??DDDFBFFFGFGICGIIIJJGCDGGDHGIGGFHIIGGIIHJFIDHIIJIJIJJIADGGIIIIJIJGAE8?BCCDDB@@BDCCACCCCACCDDDDDBAAA
@10S
ATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCC
+
@@@FFDDDDFHHHIIGFGFDGHCEH@HFEHIJGGEGHFHDHHIJJGGHI@GHHIEEHC=DEFCDEDDDDD@A@@CDDCDDCDC@@CCC>A>CDCDCCDD
@10T
TGGCGGGCCATGCGGGAATGGCAGCACACGAGCAACTTTGACCGGATGATCTTCTACGAGATGGCGGAAAAGTGAGTCTGGGGTCCTGGGAGCGGGGCCCG
+
C@@FDDFFHFHHFHGG@AHIJJJIHIGEHFEECBEBDCCDDDCDD;@BDEDEDDCCDDBBD?CC?BB>B9?C4@CCCDCCDDD5>BCDDBDBD>B>B@B@7
@10U
GGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGAT
+
@@@DFBDFHHHHHIHIIGIEHBHGHGGGIIGIIIIHHIIIGIIGBFGGIGHGIIIIIFHFEDEDDBDDDDDDB@CCDCDDDD>BBDD?BDDDDDDCDDDD:
@10V
GCGTCCTCCGAGTCCCACCCGAAGCCATCCAGCCCCCGGCAGGAGAGCACACGCGTGATCCAGCTGATGCCCAGCCCCATCATGCACCCTCTGATCCTGA
+
??;DDDDDH@D?AC<<?FGEDFH:DGGDGGGDEGI@FHIB<=8?1;;;;6(=;@B,28ADCCCCCC@CCCCCC<@B@BBC9(::A@CCB?@?@CDCC::@
@10W
TTTTATCATCCCAACATTCTGAAGCAGCTTGGAGTTTGTTTGTTGAATGAACCCCAATACATTATCCTGGAACTGATGGAGGGAGGACACCTTCTTACTT
+
;==AA4AA,?AA7+++2<4CA9<77?++??7)*::?A?B))*000=**9AB9AA<A<>==)8/8=>)7=;A9)=>).7>;>@@====(,(855=???:(8
@10X
GCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACA
+
@CCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJIJJJHJJJJJJJJJIJJJJJJHHHHFFFFEEEEEDDDDDDEDDDDDDDDDDDCDDCDDDDDD5<BDD
@10Y
AGAGAAACTATTGCAGCTTGCCAGGACCTTTGAGGGCCAACAGCCCACCCTTGAGGTCCAAAGAAAATCAAGAACAGAGCTGTGAAACCGTAGGGCATCCC
+
<??DD8BDDD?DD99EEE+AA3:3AEECEEC9C)91)6DDDDBDD;/?-@=CD;73)7@3).==CCDDA37)6;;;;>(5(5AA(;:>2',(288(2<AA>
@10Z
TCTGAGAAACAGCACTCATAGTAGCACAGCTGCAGACTTACTACAAGCCAAACAACAGATCCTCACTCATCAACAGCAGCTTGAAGAACAAGACCACTTAT
+
@@CFFFFFHHHGHJJJJIJGJIIGIJJJIIIIIJJGIJJJIJJJIJJJJIJJGJJIJIFHIJIJIIIJIIJGHHHHFFFFEEEDEEDDDDDDDDDDDCDDD
@110
CACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCA
+
@@?DFFFDHHGGHIBHGIGIEDHGAFBGIIGHIGGEBGHGCD??B?DGBHHIBGGHGB>DEEHEHCFEDDDCACEC?B=ABDDBACDCCC@AA>A@>CCD
@111
AGAAAAACAGATGAAGGAAAAAGAGAATGATCTTCAAGAAAAATTTGCACAACTTGAAGCAGAGAATAGCATTCTTAAAGATGAAAAGAAAACCCTTGA
+
CCCFFFFFHHHHHIJIJIJJJJJJJJJIIJJJJJJJJJJJJJJIJJJIJJJJJJJJIJJJJIJJIJJJJHHHHHHHFFFFFFEEEEEEDDDDDDDDDDD
@112
AGAAAAAGGAAGCAGAGGAAGAGGATGAGGAACTCTCCAACTTTGCTTACCTCTTGGCCTCTAAACTTAGCCTCTCACCAAGGGAGCATCCCCTCAGTCCT
+
@CCFFFFFHGHHGJJJJJIJJIIIJJJIIIIGIIJIIGIJJIIJJJJJJGIGHIIJJJJJJJJJJJJIHHHHHFFFFFEDDDDDDBBDDDDDDCDDDCDDD
@113
CTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTT
+
CCCFFFFFHHHHHJJJIFIIJJJJFIJJJJIJJJJJJIJJIJJJJJJJJJJIJJJJJJJJJJJJJJIHHHHFFFFDEEEEEEDDDDDDDDDBDDDDDDDCE
@114
CCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTC
+
CCCFFFFFGDDDAGGBFGHGGIIEGGIGHEHIGEGGIJJEGGIGGI;CHHHGDHIIIGEHCHEHFFFEDFFEECEEDDDDDDDDADDDCDCCBB@@BCBCC
@115
CCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTTATGGG
+
CCCFFFFFFFBD=FABHGG@CCHGGGIGDGGFHIIIIGIGAHGDAGGHBGFHH?HHHHGGGHHGHHC9BBABD??ABDBBBBCDCDCDAB?+55<9@CDCB
@116
ATCAGGTGGTCGTACAAACTGCATCAGGAGATATGCAAACATATCAGATCCGAACTACACCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATGACATCT
+
@C@DDFDDHFHFHIIJJJJIJJJIJIIIJJJHGIJJJGJJJJJIIJJJIGHIGIJJIJJIJJJJHHHGHHFFFFFFFEEEDEDDDDDCCD9?CDDEDDCDD
@117
CCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCT
+
@@@F=DDFHGHHHGIIIHGCGHIIIEIGG?D@DGCCGEGGDFHGGHEF@FHIGGGGEG==CAADGECHAHEDDF=AAA@DDDB@BACACCDCCCDD@C>AA
@118
CTGAAAATGAGTTTTCTTTAAGGCCAATTGACAGCAACACGTTTGAAATGAATGGCAAAGCTCTCCTGCTGCTGACCAAAGAGGACTTTCGCTATCGATCT
+
@?@DDDDDHHGHFIIEHIIGIGGGIGIIIEGIGIGGGHFHGBGHGHIIEHIGIIIGIIEGCDGIIIIIIGEICHHFHFDEE>AC@BDCDCDDDDDDDBDDD
@119
ATTAAACAGGAACCCAGAGATTTTGCATATGACTCAGAAGTGCCTAGCTGCCACTCCATTTATATGAGGCAAGAAGGCTTCCTGGCTCATCCCAGCAGAAC
+
@@@DDDDDFH?FFHGEGH@GHGHFEGGHEGHIII@FIGIHIH9FFGBFCGCHIIIIBBEGFII@;CHG9@EHGHFHBDECDECCCB@C@CCCBC@ACB9:9
@11A
GTCTTGCAATCTCTGAAGATCATGTGGCCTCAGTGAAAAAATCAGTCTCAAGTAAAGGCCAACCAAGCCCTCGAGCAGTTATTCCCATGTCCTGTATAACC
+
@@@FFDFDFBDAFGGGGADIHIIGHG@HBFBGEGICHIIIGGGCHHCHGEDE?DDADB=FHIIIIFH?EHGDBDCDDDDCDDC@C@C@C@C>ACDCCBC:>
@11B
GGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCC
+
?@;DDDDBFFHF>EHIIF;@B@HDBHIH@?DGAHF@;FD=FGICGCHIHGF';A?EHB3;>B7;A>CC;>C>>@C@@<?B:@>C>ACCECCCC@??@?<@
@11C
AGGGGGGATAAAATAGATAGGGTGGGGACCTATTTGGTAGGGATAGGGCCCGTGATGGGAAGGGGGTGGGGATGGAGGGGGAGGGGGGAAGAGGGGAGGTC
+
+11++),',,((((((+(+3(+((&&)+&++(((+(32++(((((+((((&)&)2+((2(++(&)))&&)&+)2((290&&)0&&&09&&+(((&&&)&+(
@11D
CTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCT
+
CCCFFFDFHFHHGJIJIJJJIIIJIHJJGIGIIIIHGJGIIIIJJJGGIIIIIGJIGIIIGIJJIEIHHHFHFFACBBCCEEEDDEDEDDDCCCDDDDDDC
@11E
AGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCAC
+
CCCFFFFFHHHHHIJIIJEFGHIJIGGIJDGIJJGGGHGIIGIIEHIIIIIJIIJHJIJJEIJJJHHFFFFFEEDEEDDDEDDDDDDCDCDDDDDDEDDDD
@11F
TAGCTCTTCTGGATGACCCTTCAAATTCTCATTTTATTGCCTGGACTGGTCGAGGCATGGAATTTAAACTGATTGAGCCTGAAGAGGGGGCCCGACGTTGG
+
:?;:A?:AF?2C<<?<ACC?AGFBB<??9C<4<A<??9:99??GF@GIB0960?D;(88(.7@CE@=A)=C777.;7;;;;..;-(;'8;3050&5<&2+<
@11G
AACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJEGHGIJJJGIJJJJJJJJIIDGGIGIJIHIJJJJJJIEEHGHFFFFECDEEEDCCCDDDDDDDDDDDDDDDD
@11H
GAAAAACAGAGAAGCTGCTCGAGAATGTCGCAGAAAGAAGAAAGAATATGTGAAATGCCTGGAAAACCGAGTTGCAGTCCTGGAAAATCAAAATAAAACTC
+
@@@DDEFDFHDAHGHEIGCEGGJIFIIIJJJJJIJGGIGGGIIJGIIFJI<FGHI@GHIGHIDEHFADFDC?BCCCCAACCDDDDDCACDDDDCDDDDCDC
@11I
CGCCAGTGTCCCCACTGCATCATGCATCTCCAAACTCAACTCATACACCGAAACCTGACCGGGCCTTCCCAGCTCACCTCCCTCCATCGCAGTCCATACC
+
B=@FFFDDHBHHFIIJIIJGJJJHIIIIGEEGEEFGGGIJIGGIIJJIJBEGIIGGHIJIJHDFDDEDDDCCBCCCDBDDDDCDDCCCDDDDDDCDCCDD
@11J
CTGAATATAAAATTGCAAGATACTAACTCTCAAAAGGAAAAACTCAAGGAAGAACTAGGACTAATTTTAGAAGAAAAGTGTGCTCTACAGAGACAGCTTG
+
CCCFFFFFHHHHHIJIJJJIJJJJJJJJJJJJJJJIJIHIJJJJGJJJJJJIJJJIGIJJJJJJJJJIIIIJJJJHHFEHDDFFFFEEECEEDDDDDDDD
@11K
CTGATTTGGGAGATTTTAACTCTTGGTCATCAGCCTTATCCAGCTCATTCCAACCTTGATGTGTTAAACTATGTGCAAACAGGAGGGAGACTGGAGCCACC
+
CCCFFFFFHHHHFIIJIJJJJJJJJIBHIIJIJJJJIJJJJJJJJJJJJJJJJJJJJIJIIIIIJJCHJJJJJCHIIJJHHHHFFFDCDDDDDDDDDDDDD
@11L
CTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGC
+
+??BADDDFFFFFBFF>9?FFIIIIIFIEFIIIIFEFFEEEFIIFICFCIIIDIIIDFC@FADEEECAEB@DBDBCCCCADCBBBBBB?BABABBB9?BB
@11M
GAAACATTGGAAATGGGTGAGGTCGTTGAAAAGGATACAACAGAACTCATGGGAGAACTTGAGGTAACCAAGAGAGAGAAATTAG
+
-(09@4=9681=<@166<=(68))(256(:.;<97)7=>?17=>1133<109(.(-(<;>=?>;;;;.:6=((.(,,3(-:7;;7
@11N
GTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACT
+
@@@DDDBDDCFFFFFHHIIII?FH<FHGGCHGEFAGDCBDCF@@9BBFBGHGGB>GHI@FAHHGIGGDEECHEEEDACCCACC@>>C>;@CCCC??AB.55
@11O
AAATTCTCGCCTCTATTGAGCTGCTGGCCCGCTCATTGCCAAAAATTCACCGCAGTGCATCAGAACCCTCCTTGAATCGGGCTGGTTTCCAAACAGAGGAT
+
@<=BDD?B?;@@@FCAGIE<F?A9F????CCG6:DB?<B?B8DCBB=F;==GI<:A>C?D@?@7BCAB@=@?CCC@A:<=;9@@@?@?@>A:>B?CCA<89
@11P
AGATGACATTATGCCAGTTGCTTTAATGGAAACGAAGAACCGAGAAGGGTTAAACTATAAGGGACTTGCTACAGAATGGGGCCAAGGCGAAGAAAAGGCTG
+
:7++2,++2<+,2++2<2++?A4ACC4A<<A<+?)111:=)0)).;=A<(.=788>977)=>(.5>)7;;3))7;(.((((',((95(,&0&5(++(2(32
@11Q
CAGATGTATTTGCATTTGGAATTGTTCTGTATGAATTGATGACTGGACAGTTACCTTATTCAAACATCAACAACAGGGACCAGATAATTTTTATGGTGGG
+
?<=A;D?AF:AFDDE@G@EHEHIIIGC?E:CFH4A22<?EH91?BD*)?;BBD>D4DBFGH>F?DBD=BCBBGCGEGI@;C=CD<B@;?@CCAC6>-;18
@11R
AAAGTCCACAAATTCGAGCATCAGATTCTCCTTAGCCCTCTTCACAACCTCTCCAAGTTCTCAGACAATTTCCTGATTGCATGTGTGGTACTCCCACCAA
+
((-<<4;<)933)=994@5/)39).)..<4))))1).;9393:>>3=5;969)0)))/).)/))).().).).)))).))))..).6(.(.(((,69'8;
@11S
CATGCAGTTTGAAAAGGACAATTTGATAACTAAGCAGAATCAATTAATTTTGGAAATTTCAAAGCTAAAAGATTTACAGCAGTCTCTTGTAAATTCAAAGT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJIJJJJJJJJJJJIJJJJJJJJJJJJJJJJJIIJJJJJIJJJJJIJJJJIJJJHHHHHFFFFFFEEEEEEDDEDDC
@11T
CGCCGCCTCTCCCCGGCTGAGAGAGCTCAGGGACCCAGGCCGCACCAGGAGAACAACCACCAGGAGTCCTACCCTCTGTCAGTGTCTCCCATGGAGAATA
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHFFEDDDDDDDDDDDDDDDDDDDCDDDDDDDDDDDDDDDCCDDCDDDDDDDDDDDDD
@11U
GGAGGATCCAAAGTGGGAATTCCCTCGGAAGAACTTGGTTCTTGGAAAAACTCTAGGAGAAGGCGAATTTGGAAAAGTGGTCAAGGCAACGGCCTTCCATC
+
CCCFFFFFHHHHHAEHIJJJJJJJJJJJJIJJJJIJJJGIJJJIIIIJJJJJJJJJIJJJJJJJHFFDDEEEDDDDD@CDDDDDDDDDDDDDDDDDDDDED
@11V
CAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAAC
+
CCCFFFFFGHGDHJIJJJJJJJJIIIJJJIIJIIJJJJJJIJJJJJJJJJJIIJJJJJJFJJJIHHHHHFFFFFFEECEEEEDDDDDDDDDDDCDDDDDDD
@11W
GCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATAC
+
CCCFFFFFHFHGGJIJJIJJIJJJJJJJIFGIIIIJJJJJIJJJJJJJJJJIJGHJJIGHHHHFDDFDEEEEDDDDDD2=@CDDCDDDD@CCCDDDDDEDD
@11X
CATCCCCTTCCCACCACAAGGCTTTAAGCAGGAGAACCACGACCCAGTGTATGAACACAACACCATGGTTGGCAGAGCGGCCAGCCAAAGCTTTCCCCCTC
+
<@@BDDB?CDADB3CEFF;CG9<FCCHIIEFA1D):9B?BB6(;A8=.=@F=9;@7=3??;;;;?@;>A>=BC(5(552/-&)8<<?CC?9C44::ACBBB
@11Y
GAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGAC
+
CCCFFFFFHHHHHJJJJJJJJJJIJJJIJJJJJJJJIJJJJJJJJJJJIJJJHHHHFFFFEEEEEEDDDDDDDDDDDDDDDDDDDDDDDDDDDDDEDDDDD
@11Z
CTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCT
+
<@@DD?BDDFFBD8<E:FEFDCEFEEFDBDF<DGEIFFII@FF<BFIIIIF87=@F>EE>AECEFDBB?ABB@CBBAA;@@>:A@<;BBB@?<A@9?>A?:
@120
CAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCC
+
CCCFFFFFHHHHGIJHIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJHHHHHHFEFFEEDDDDDDDDDDDEDEDDDDDDDDDDDDDDDD
@121
GGAATTTAAACTGATTGAGCCTGAAGAGGTGGCCCGACGTTGGGGCATTCAGAAAAACAGGCCAGCTATGAACTATGATAAACTTAGCCGTTCACTCCGCT
+
@@@DFFFBHHHHHJJIEIIFHGIGJJJJJCGHIJJIGIIHGIJJJDIJJIJJIHHHHDFFFDDDD@CCCDDEDDDDCDDEDDDDDDDACBBDDDCDDDDBB
@122
CCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGC
+
?;==?BDBFF?:??CG4:4:FHEB@@FG;C:FF<F?9BFGD<99DB<B89BC<BBFBFIIFAA@EEA;C=E;BDBDBCCB@/88=??5?B@AB>AB8<
@123
ATCTCCTGTGACTCTCACCTCTCAGACAACTAAGACAGATGACCCCCAATTGAAAAGAGAAATAAGGTTAATGAAAAACAGAGAAGCTGCTCGAGAATGTC
+
;=@BDDBDFHFHBDF@FGGHGHFA@BGCGGGGEGIIIGABCFHEHEHGGEFG@FEBF;C@CC=@GIG7;=EEAHCCDDDAC;@AC=>;>?5:88?A?AC44
@124
AGCAGATTCAGGTGTTCATTTATGTGTTATTGATGACTCCAATGAGCATATGCTTACTGTATGGGACTGGCAGAGGAAAGCAAAAGGAGCAGAAATAA
+
CCCFFEFFHGHG?FEHIJJIJJJJIJIJJJJIIJJJJJJJJJGJJIJJIJIIIJJIIJJIGIJGIIJIIFGGIFIJIHHHHHFFFFCCDDBCDCDDDD
@125
CTCCAGGACCTCAGCGAGAAAGGAAGTCATCTTCATCCTCAGAAGACAGGAATCGAATGAAAACACTTGGTAGACGGGACTCGAGTGATGATTGGGAGATT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJIJJJJJJJJJIJJJJJJJJGHHHHFEFFFFDDDBDDDDBDABCDDCDEDDDDDBDD
@126
CTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATG
+
CCCFFFFFHHHHHIJJJJJIJJJJJJJJJJJIJIIJIJJJJJJJJJJJJJHHHHFFFFFDDEEEDDEDDDDDDDDDDDDDDDDDDEDDDDDDDDDDDDDDD
@127
CCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGAT
+
?@@FBBDDDHHHGIIGHIIFIGGFFC>HDGFCEGFEFIGD>HFAGHJFIGEG@ADH>38BECFEBG@AEEEEDD;>BCEC@AAAC?>?CDCCDCDBDBB?C
@128
CACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCG
+
CCCFFFFFHHHHGJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIIJJJHIJJJIJJJJJJJJJJHHHHHFFFFFFFEEEDDDDDDDDDDDDDDDDDDDB
@129
GTCACATCAACGAGGAGGACACAGTGCCTCTTTCTCACTTTGATGAGAGCATGGCCTACATGCCGGAAGGGGGCTGCTGCAACCCCCACCCCTACAACGA
+
B@CFFFDFHHHHHJIJJIJJJJIJIJIJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJIJJJJIJHFFFDDDDDDDDDDDDDDDDDDDDDDDDDDDDCDD
@12A
GTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCC
+
B@@FFFFFHHHHGJJJJJJJJJIJJJJJIJJIJJJJJJJJHIJJJJJJJJJJJJIICHHJJJIJHHHHHFFDCDDDDDDCEDEEFEEDDDDDDDDDDDBDD
@12B
CTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTC
+
CCCDFFFFHHHHGJIGIJIIIGGJJGIGHHIJJGIGGIGGHIIIGGIIJGGAGGGIIIEGFGAGHGFEHFDDDDDDDDDDDACDB?C<C?4@>@CDCCDCD
@12C
CTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGC
+
CCCFFFFFGHHGHJJJJIJJJJJJJJJJIJJJJIJJJJJIJJJJJJIJJJIJJJJJJIGJJJIJJHHHHFFFFFFEEDCEDEDDDDDDDDDDDDDDDDDD
@12D
GGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGAT
+
@@7DDFFAHDHHBDHIIGHA9EHHGIGGDFBHGEHFFHGGGIII@CGGIIIIGFGGGFHFDBECABBBA9>ABCCCCCCCCC@BBB>?A<BBBBCCCCCCC
@12E
TGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCC
+
@@@FFDDFDBDDHHIHIJEHHHIDHIJIIJJJEHGEHGIJFEIIIHGIGDGHEFHEHDEEFFFEE>BBDDDBDDBDDDDCDDBACCCDDDDDCDDDBDD
@12F
GCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCT
+
@CCFDFFFHHFDDDHFHHGHIJGGIJGIJJJJFFHGGGIJIJJJIJJJCFGGGGGCE?E?CHFBDECECACACCCCDBB@B9<A>CCDBB<ADD<<ABA
@12G
GGAAGGCCTCTACAACCCCACGTCAGAGTGAGGGATTCTGTTACTCTATCCACACTGCAGATTCTTGGACTTGGCACTTTTGAGCGTGGAGC
+
++8=4++22A<:CBE3?E)C::<:?ED@*:*1??))0?*999*0*9*/==8=;);888)77@@..=3=C7).;;7)6((.;(5;;>;??159
@12H
GAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACC
+
=@<BBDD?FHHF@GIBF<@GHDEBGGII@D9D9DHDHBHE<;D;F:AG@ADDEBA@BBEE6;@@@CCCCA3;?@@BBB@8<89?C@C8>>A@A>C<??A?
@12I
GAAGTGCCTAGCTGCCACTCCATTTATATGAGGCAAGAAGGCTTCCTGGCTCATCCCAGCAGAACAGAAGGCTGTATGTTTGAAAAGGGCCCCAGGCAGTT
+
@@@?BB>DA?DHFGIBHHIII<FHGIEBHECEDH?FEBFHIFFGBAFGGEEHEHIIIIIIDEGG@EGGE;A6=?D;?;?CC>6>ACC=??BBB<@?B@@?A
@12J
GTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCC
+
1:=;DDDDHF>BFHIIEBG@:+<CAGGGHEIEHGBGGGG;B)?BGH(<A8FGIGGICHAEHCH>>?DCDECCCC@CABCB3:@CC@CCCCCCCCC>>A(8?
@12K
GTTCTGTATGAATTGATGACTGGACAGTTACCTTATTCAAACATCAACAACAGGGACCAGATAATTTTTATGGTGGGACGAGGATACCTG
+
@@@FFFDDFHHFHGGIGEHHJJJIJJJHHHIIHIFHGGIIIIGGGIIJJJHHJIJGEHGHJGHHIJJJIIICE>CHF?DDDDDBCCCCCA
@12L
GGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTAC
+
?@@DFFFFHHFFHDHGI>DFGGGBGIGIBFGHIIIGHHFGHHIIIIG>BFDFH@HGG>EHGFA>EEDFFEEAEC@AAACCC@BBBCCCCCCCCCCCCCC
@12M
GCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGT
+
CCCFFFFFHHHHHJJJHIJJJJJJJHJJJJJJJJJJJJJJIJJJJJJIJJJJJJJJJJJJJJJJIJJIHHHFFDEDEEDCDDDDDDDDDDDDDDDDDDDDA
@12N
AAATCATAAAGACAGCCAGTTCGAAACTGATATAGAACAACGAATGGAACAAGAAACACAAAGAAAGTTAGAACAACTCCGGGCAGAGCTGGATGAGATGT
+
CCCFFFFFGHHGHJJJJIJJJIJIJJIJJIJJIJI9DGHIJIEIJJIJIJJJJJJJJJJJJIIJJHHHHHFFFFFFDEEEDDDDDDDDDDDDBDDDDCCDA
@12O
CCTTCGCCCACTTATCGTATAGTTTTATACTCAAAATACCCTAGGCCGGCGAAAACTATAACAGCTGAGGATGCCTGCGCACGAGCTCGCACACAAGCATG
+
((0@-(0@(<(;)))).)().2):).).:1:.)))2)1=)<):3)<0((7'-'5'(6((((7(-6--98(((,((,(()&5&&0&)&(&)&))8((+(+++
@12P
CACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCCCCGGGCAGAAAAGTTCATTCCGACAGGACC
+
?<@+BDDDF?FFF7<@:F?389?CF+*?<FDG3:?DB8DF*?F*09?BDAF*8)88=FFF>=)7@C=6((((',''388(5(((+:>:::>:39<9>?BB(
@12Q
TCAGAATCCTTCCCCTAGAGCAGCTGGGGAGAGGGACGATGTCTGTCTCAGCCCAGGAGTTTGGCTGAGCAGTGAGATGGATGCTGTAGGCTCGGAGCTGC
+
@@@DFFDDHFFDHGEGIGIEIGIIIJIIIECFDGFHGI<GGIDEIIJIEGIJIG=DCEH@?CEFC>?CAC<?5;;@C@CCA:CBC>@ACCCD(5>>@>D??
@12R
GCTTCATTTGCAAAGAATAAATCCAACTACAGTGAAAATGAAAAGTTCTGTCTTTGATGAAGACAAAACTTTTGTAGCAGAAACATTGGAAATGGGTGAGG
+
@@CDDBDFHBH?FGIIIBHHEHHIIIIIIIEGACFHGEHIIIHIIDFGGIIGGGHI@GGDGEEDDGDHIIGHIIHIIIIIGHHHHFFFFFFCECCE@@?BD
@12S
CAAAAGATAGAAACCATGCAGTTTGAAAAGGACAATTTGATAACTAAGCAGAATCAATTAATTTTGGAAATTTCAAAGCTAAAAGATTTACAGCAGTCTCT
+
CCCFFFFFHHHHHJJJJJJJJIIJJJJJJJJJJJJJJJJJJJJIJJJJJIIJJJJJJJJJJJJJJJJJJJJJJJJJHHHHHHFFFFFEEEEEEEDDCDDDD
@12T
AAGAATTGAGCTTTTCAAGGGAACAGATTCAGAGAGCTAGACAGACAATAGCTGAACAAGAAAGTAAACTTAATGAAGCACATAAGTCCCTTAGTACAGTG
+
@;?DDDDDFDFFFI9FG<HFG<>F?9CFH<9CF>?;@AGFF9<D9BDFCBEFD>FGEFFIIIIF7=CEDEAEEECCECFDDDDDDB;>BC;@>AADBAA>A
@12U
GAGAAATTAGAGCTGTCACAGAGACTGTCTGATCTTTCTGAACAATTGAAACAGAAACATGGTGAGATTAGTTTTCTAAATGAAGAAGTTAAATCTTTAA
+
@@CDFFFFHHDHDEHFHGGIHHIIJJJHHIJIHIIJIHHHIIJJJIIIJJJIJJHIIHIHHI<CGGGHHJICHIIJJIJGHHEHHCEFCEFFEEEEEEED
@12V
CACCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATGACATCTCCTGTGACTCTCACCTCTCAGACAACTAAGACAGATGACCCCCAATTGAAAAGAGA
+
@@@?DDDDFDDFDBEGGAEAG9?<FHFBAFC?E?:1???BG?FGGGBC?BFCHCIEGHGIAABBDH<FHEAGA@ECEHE;7777;?B?B<A@CCCC?<?9
@12W
CCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJHHHHFFFFFDDEDDDDDDDDDDDDDDDDDDD
@12X
CCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATG
+
CCCFFFFFHHHHHJJJJJJJJJJJIJJJJJJHJJJIJJJJJIJJJJJJIJJJIJJJJJIJJJIHHHFFFFFEEEEFEEDDDDDDDDDDDDDDDDADDCDDD
@12Y
ATTGAAAAACTTAAAGATAATTTAGGCATTCACTATAAACAGCAGATAGATGGTTTACAGAATGAAATGAGTCAAAAGATAGAAACCATGCAGTTTGAAA
+
CCCFFFFFHHHHHJJJJJJIIJJIJJJJJJJJJJJJJJJJIJJJJIJJJJJJJFHIIJJJJJIJJIIIJJJFHGHIJJHHHHHHFFFFFEEEEEDEDCDD
@12Z
CCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTC
+
C@@DDFFFHHHDHDFHGDHGGIIIGGCBGHIIIGHIII@HHGGGGEEGIIABGFFHCEGIE@EHHFHCEFFFF@?C@CCDDDCDDDDDCDCCD59?BBB
@130
CAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGAGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGC
+
???=B::2=BDDD88CE?EEEBBCDDIIDDBDDD?DDD'<B<=C@C@==).====7.)77@?>A@@;>5>A>AA:5:(:AA??<?>?<?<>84<?>>AAA
@131
GTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGC
+
@@@DDDDDDHFHFAGBEGEEHG>DBBEHGECBGGDGI?CHHDCHGGHA:A;BBF@GI>=EDDCHH7=77;;7@>CCCCA@>CBB;;AC<CCC>C?AC<?
@132
AAGAGGAAGAGGAAGAGAATAAAAAAAGCAAAGCCAAGGAACCTCCTCCTAAAAAGACGAAGAAAAATAATAGCAGCAACAGCAATGGGAGCAAGAAGG
+
1=;+@?3+2+<7+2++@CC77+AC=?4??37:=959=A5(.=588..887)..7A:7),'9@@@;=;(;5=?935,,,5,9+(39(+(+(8;883839<
@133
TGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGAT
+
C@CFFFFFHHHFGBEGHJIIEGHIIIIIIGHIIJJIJIJIIGIIIIJJGJIIGHHHGGEEA?ADFFFDDEA@CCCDC8;'8:ACBDD<ABCCCDDDDDCD
@134
CAGAACCCTCCTTGAATCGGGCTGGTTTCCAAACAGAGGATTTTAGTCTATATGCTTGTGCTTCTCCAAAAACACCCATCCAGGCAGGGGGATATGGTGCG
+
@BCFFFFFHHHHGGIJJJJJJJJJJBGIIJJIIJJJJJJJJJJIJJJIIIIJJJIIIEGEHIJIGHHHHGFFFFDDDDDDDDDCDDDBBDDBDDDDDDDDD
@135
GGGTGAGGTTGTTGAAAAGGATACAACAGAACTCATGGGAAAACTTGAGGTAACCAAGCGAGAGAAATTAGAGCTGTCACAGAGACTGTCTGATCTTTCTG
+
BCCDDFFFHHHHHJJJJJJJJJJJIJIJJJJJJJJJJJJJJJJJJJJIJJFHIJIJJJIHCHHHHHFFFFFFDEEEEEDDDDDDDDDDDDDDDEDEDDDDD
@136
ATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATG
+
CCCFFFFFHHHHHJJIJJJJJJGHIGIJJJJIJGHJJJJJIGIGIIJIJJJJJJJJIJJJJJJIJIHHHHFFFDDDEDDDDDDDEDDDDDDDDDDDDDDDE
@137
ATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCC
+
@@CFFDDDHHHHHJJJJJJGFGDHGIBHFGHIJHIIJJJGJIIJJJJIIFHEHFHF;BEFEECEEDBBDDDBDDDDDBDDDDDDDDCDDEDDCDDDDDDD
@138
TTCAGAGGTAAATGGTTGCAGTTTTGTGATGAGAACAGGAAAGCCTACAAATTTATTAAGGGAAGAAGAATTTGGTGTTGATGATTCTTATTCTGAACA
+
@@<DDBDB=CADHAEHBGCFEIIIEB<?4CBABFGFHCAHIIIIIGGBGEGBHGGFIIGIEABGCDFG@@DEHHF(;??=BDAA>C@ACACD;;CAC>:
@139
GTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAAC
+
<?;DD??><?=CFGAGFFEGHDCGGCFD8CF:E11CD@9DFDGE>GB>D<?FGI<;;55C@7=>7?A?;@@>?>BCC?;5;@;?>,,;:(;5>55:><B
@13A
GCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGG
+
CCCFFFFFHHGHHJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJIJJJJIIHIJJJJHHHHHHFFFFFEDDDD8?BDDDDDDDDDDDDDDDDDDDDDDDD
@13B
GGGGTTCTGATGCACTGCGGTGAATTTTTGGCAATGAGCGGGCCAGCAGCTCAATAGAGGCGAGAATTTGGGGAAAGAGTGGTCTCTCATCTCTTTTCTTT
+
@@@DADFFGHHHGJJJHIIICGIGIIIJJJJJFIIJJJJJJJJJJJHFHEEDFFFFE>CBCD?B;7@CCDABB@BBDCD4>B::>@CDDCDDDDDDDCCDD
@13C
CTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTAT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHHHHFFFFEEDEEDDDDDDDDDDDDDDDDDDD
@13D
CCCCTATCCTGGGATTCCTCCTGAGCGGCTCTTCAACCTTCTGAAGACCGGCCACCGGATGGAGAGGCCAGACAACTGCAGCGAGGAGATGTACCGCCTG
+
@@@FDFABFBHFFEHCBHGGG:CBFDDGF6@?FHIGEG@HGDFFEG8BGBGIE:BDFB3>BBC?>@??<9??8A?AC9ACCCB>>BBBACC:>@>55<58
@13E
CTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTT
+
CCCFFFFFGGFHHIIHGGHHIGIIIJJIJIJIJJIJJEHIIJJJIJIGJJJHIJJJIJGIJGIIGIIGHHHFFFFDCCEEEEDDDDDDDCAABBDDDDDCD
@13F
AACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJEGIJJJJJJJJJJJJJJJJJFHIJIJJJIJIJJJJJJHHHHHFFFFECEEEEEDDDDCDDDDDDDDDDDDDD
@13G
CCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTTAAGGG
+
CCCFFFFFHHHHHJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJHIIGHHHHHFFDDDDDDDDDDDDDCDDACCCDD9>@BDD:@CD
@13H
CACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTG
+
>=;AAA+<7=+<<,?7>C7A>A>B+)?AAB?A>AA==::?BB<2=>3==*=<AAA;))8)8>)5=AAAA>@@3;7>@;53>;>?;>;(,5;;?:3(53938
@13I
CCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTTATGGGCAGGAGT
+
CCCFFFFFFFGHHJIIIJJIIJJIIJIJJJJJJJEHJJIJJJJJJJJIJGIFHIIJJJJIGHGFFFFDDDDDBBDCDDDCEDDD55<@CDDDDDDDDDBD?
@13J
CGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCGAGGATATGCACAGACCACCCAGGC
+
@@@DDDDDF<DFHGHGBFHFGGII@@EGE?EFHHGGGHBGIIGHBBGEGGHEGGGGEHEEHHBECB??ABBBBBCBBBBBCCCCCE@C?CBBCBBB@???
@13K
TATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACC
+
CCCFFFFFHHHHHJIJJJJJJJJJGJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHFFDDDDDDDDDDDDDDDDDDDDDDDDDDDCDDDDD
@13L
TATGCAAACATATCAGATCCNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN
+
<<<@@??@?@?@@@?@@?@@#################################################################################
@13M
GAAACAAGCCCACCAGCTTGTGGAACCCAACGTACGGCTCCTGGTTTACAGAGAAACCCACCAAAAAGAATAATCCTATAGCAAAGAAGGAGCCACACGAC
+
@@@FFFFFFFHGHGGAE@CBCFHIIIGGHGGG;BFHIGIGHFHEGHGGIJIEIEHHFEHFFFCDBB?@BDD>@CACCCCCEDAC?C?BDDDDBD?C?BB@B
@13N
ATTCACCGCAGTGCATCAGAACCCTCCTTGAATCGGGCTGGTTTCCAAACAGAGGATTTTAGTCTATATGCTTGTGCTTCTCCAAAAACACCCATCCAGGC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJIIJIJJIIJJJIJJJJJJJJIJIJJGHHHHEHDFFFFFFEDEEEEEDDDDDDDDDDDDDDDDDDDDDDDDD
@13O
CCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGG
+
CCCFFFFFHGHHHJJJJJJJJIJJJJJIJJJJJJJJJJJJJJJJJIJJJIIJIJJJHHHHHHFFFFEEEEECEEDDDDDD@BDDDDDDDDDDDDDDDDCDD
@13P
ATGCAAAAGGTGGCTGGAGAGAGATATGTCTACAAGTTTGTGTGTGATCCAGAAGCCCTTTTCTCCATGGCCTTTCCAGATAATCAGCGTCCACTGCTGA
+
CCCFFFFFHHDHHJJJJJJJJJIIJIJJIIJJJJJJHHIJGHHGIJJJJJJJJJJJJJIJJJIIJJIGIGGHHHFFFFFFEEECEEEDDDDDDDDDDDDD
@13Q
CTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCT
+
@@@FDDBDHHHHGIGHIIIIGJHIEFBEGGHIIGIGIJGIJGHHIJIIIJJIJIJIJGHJJJGIJIIFHHDHFFDDBBCCADDCDEDEDCCCACCDDDDDD
@13R
TTCAGCTCTGGCAGTTTTTGGTAGCTCTTCTGGATGACCCTTCAAATTCTCATTTTATTGCCTGGACTGGTCGAGGCATGGAATTTAAACTGATTGAGCCT
+
@@@DDDDD?AFAFGECGGGEGEHEGHHIGBDCCH>DEHHDHII<FHIDHEHGCGEDHGGIIGIIBGCHII=@E6BECCCCBCCCCCCECCCCCCCCCCCCC
@13S
CTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCT
+
?8?BABDDFFFFFA1:8ECE9<CCFGGEFGDEGAEEB?FFDD@BBFBCFE3CF9=FCAEA9@=8AB2@BAABC;??9;5;;@BAABBBBBBBBABBBB:<@
@13T
CGTATGAGTCGGAGGAAGAGGACAAGTGCAAGCCTATGTCCTATGAGGAGAAGCGGCAGCTCAGCTTGGACATCAACAAGCTCCCCGGCGAGAAGCTGGGC
+
@@@FFFFFHHHHGJJJJJJIJJJJJJIJJIIJJJIJJIIIJIJIJIJJJJIJIJJJHFFDDEEDDDDDDDDDDDDDDDDDDDDDDDDDDDBDDDDCDDDDC
@13U
CATCTCCTGTGACTCTCACCTCTCAGACAACTAAGACAGATGACCCCCAATTGAAAAGAGAAATAAGGTTAATGAAAAACAGAGAAGCTGCTCGAGAGTGT
+
CCCFFFFDHHHGHJIIJIJJJJIJJJJIIJIJJHIJJIJGGIIJJIJJIEGIJGIIIJGIGHHGGIJJAEHEHHHFFFFDDCCEDDDDDDBDDDBBDD:>@
@13V
TGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGG
+
CCCFFFFFHHHHGIIJJIJJJJJIJJIJJJIJJJJJJJGIIJJJJIIJIHGGIJHHHFFFFDDEDEDDDDDDDDDDDDDDDCCDDDDDDCEDDDDDDDDBD
@13W
TGAGCTTTTCAAGGGAACAGATTCAGAGAGCTAGACAGACAATAGCTGAACAAGAAAGTAAACTTAATGAAGCACATAAGTCCCTTAGTACAGTGGA
+
CCCFFFFFHHHHHJIJJJJJJJJJJJJJJJJJJIJJJJIJJJIJJJIJJJIIJIIJJJCFHJJJJJJJJJJIJHHHHHHFCFFFFEEECEEEE@CCD
@13X
GGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTT
+
@C@FFFFFHFGHHJJJIJIJIIJJJIHGIJFGIIIJJIJIIIEIIIJJJJJJJIJIJJJFJIJGGIIGHHHHFFDDBDCEDDDDBDDDDDACEDAACAAC
@13Y
GGAAAGTGAAATTTCAACCACAGCAGATGACTGCAGTTCAGAGGTAAATGGTTGCAGTTTTGTGATGAGAACAGGAAAGCCTACAAATTTATTAAGGGA
+
@C@FFFDEHHFHHJJJJJJIJJJIJJHJJIIJIIJJJIIIIGIGBDHIJJJ@GHIJJJJJJJHGIIGCGJJIHIDEHGHFFFFFEEEECECDCEECDDD
@13Z
CAAGAAGGAGCCAGCGCCCATGAAGAGCAAGCCCCCTCCCACGTATGAGTCGGAGGAAGAGGACAAGTGCAAGCCTATGTCCTATGAGGAGAAGCCGCAGC
+
==<AAA7>A+<A+2?0A68A?3@4:A3?>??AAA:AAAAA3>;=>93=.7=4:64',6=;;(55===(55;(,593;8:88?;:(8;?=:9(889+&)003
@140
CAGCGGCCAGTGTACATTCCGAAGAAGGCAGCCTCCAAGACACGGGCCCCCCGCCGGCGTCAGCGTAAAGCCCAGAGACCTCCTGCTCCTGAGGCACCCA
+
@@@FDDFFGGCFFGGIJJJIIJIFDCBGEIIIIGIIIIIDIEHIGBHHEFFD>BB5<BBBBDBDD??BB@:ABD<?AC?B>ABCCDACCCCCCBBDDDDD
@141
CGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTAT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJBEFFFFFDDDDDDDDDDDDDDDDDDDDDDDDDDCDDDDDDDDCCDE
@142
GGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTC
+
@@CFFFFFHHHHHJJJJJJIJJIIJJIJIIIJIJGIGIIJJJIIJGGIJJGIIIGIJIIHIIEHFHHHGFFFFCEECCDDBDBBCDDDDDDDD??BDB:A@
@143
CCTGTCAATATTGATGACTTGATTAGAGACCAAGGATTTCGTGGTGATGGAGGATCAACCACAGGTTTGTCTGCTACCCCCCCTGCCTCATTACCTGGCTC
+
CCCFFFFFDFHGHIJIIIJIIBGIJIJIIJIJIJIHIIGIIIGG?FFGIJIJJIJJJIJJGIIJJ@EGFHHGHHFFFFECDBD?@DDCDDDDEDDDCDBDD
@144
CTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGCTACAAACAGCCCAGCCTAGGATATGGACAGAGTAAC
+
??;BDA:33<:1?@:1??131:?CDB9DB?:)990?D*?0/09=B@CCE7@A4@747777.(5,',,(:>(,5(5221((2<:<AAAAAA:>:>?A>3(:A
@145
CCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGAT
+
CCCFFFFFHHHHGJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJIJJJJJJHHHFFFFFEEEEEDDDDDDDDDDDDDDDDDDC
@146
AGCTGGGCCGCGTGGTGCACATCATCCAGTCACGGGAGCCCTCCCTGAAGAATTCCAACCCCGACGAGATTGAAATCGACTTTGAGACCCTGAAGCCGTCC
+
@@@FBBBBFDFHDFDGEGGHIIGEIIFHDHBFGIE<FBEGIECE=ACDD3?DCE@CFECB?B???BB>@BCCCCAC<?BBBBCCA@8A?BC?3>4@B9>BB
@147
GGTCAAGGCAACGGCCTTCCATCTGAAAGGCAGAGCAGGGTACACCACGGTGGCCGTGAAGATGCTGAAAGAGAACGCCTCCCCGAGTGAGCTGCGAGACC
+
@@=DDDDAFBFHD@FEDFEFCGIIIGGDFHCEBBFHIIII?DCHCCCHEI;CB@CA49=?;A@AC@CCC>;?C<:5;B?B5AB5@BB8<:>?:AC<@9@BB
@148
CAGCAGAACAGAAGGCTGTATGTTTGAAAAGGGCCCCAGGCAGTTTTATGATGACACCTGTGTTGTCCCAGAAAAATTCGATGGAGACATCAAACAAGAGC
+
CCCFFFFFHHHHHIJJJJJJJJIJJJJJJJJJJJJJJJJJJJJHIJJJJJJJJJJJJJJJHIIJJHHHHHFFFFFEEEEDEEEDDDDDDDDDDDDDDDDDD
@149
GGAAACCTCAAGCTGAGAAAGTTGATGTGATTGCCGGCTCCTCCAAGATGAAGGGCTTCTCGTCCTCAGAGTCGGAGAGCTCCAGTGAGTCCAGCTCCTCT
+
@@@DDFFFHGFHGCHEHEHGC3CFEGIHHEHIIIIIIGIIJGIEGIC;?FGDHFGIECGGIJEHHDFFFEECEDD@BDBBCCDCDC@CDA@CCCDCDDDDA
@14A
CAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATAT
+
CC@FFDEFFHFHHJIIJFEHHIJJJHIJJJJIIHIGEIIIJJJGGHIIDGHIIIJJJJIIGHHGHHGFBEFCBDCDECEDDDDDDBCDDDD@ACDDEDD
@14B
CTTTCCCCCTCCTCTGATGATTAAACAGGAACCCAGAGATTTTGCATATGACTCAGAAGTGCCTAGCTGCCACTCCATTTATATGAGGCAAGAAGGCTTCC
+
CCCFFFFFHHHHHJJJJJJJJJJJIJJJIJJJJJJJJJJJJJJJJJJIJJJJJJIJJJJHIJJJJJIJJJHHHHHFFFFFFFEFEEEEDDDDDDDDDDDDD
@14C
CCTGTCTCCAGATCTCAGTAAGGTACGGAGTAACTGTCCAAAAGCCATGAAGAGATTAATGGCAGAGTGCCTCAAAAAGAAAAGAGATGAGAGACCACTCT
+
;;?DDA?DHGFHHIIIGGHGGIBCHGHGGI:CB@GH@FGIIIIEEEIIEDDFFG>FGGEHEIAED@C=@AHE==?C>B856>CCB?CA@CCACBCBCBCCC
@14D
CAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCT
+
@CCFFDDFHHDHHGHIIJIIJIIGIGIJJGHJIIIJJIJIJIGHGIIHGGJIJJGAEHFHCFFFFFECCC;AACD@CDDDDDD9@ACDCDDDDBBDDDDDD
@14E
CCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAAC
+
@@@BDDDDFDFFH?2CGGIIC@BCCEDEGHGGGIGIIG@FHBBBDH<DGGGIEIGGHBD@GHGAGEHHE@C@@BCCCECCCCCCACCCAC>CCCCC??CC
@14F
GGTTTGCCTTCCCGGATTGGGCCTACAAGCCAGAGTCGTCCCCTGGCTCAAGGCAGATCCAGCTGTGGCACTTTATCCTGGAGCTGCTGCGGAAGGAGG
+
@@@FFFFFGHHHHIGGDFGIIEEHIIGDHIIIDIIIIGIEEGGGGIFGIIGGG@AEECEHFFFFD>@CCCDDDDDDAC@AABBD@CCCC@BB5>>B<AB
@14G
CCCCGTCGTCTGCACGCAGCCCAAATCCCCATCCAGCACGCCAGTGTCCCCACTGCATCATGCATCTCCAAACTCAACTCATACACCGAAACCTGACCGGG
+
@CCFFFFFHHFHHJJGIJEHIIIJJGHIJJJJJJJGIIJ@FHIJHIIIJJJHHHFFFDFFFEECDECCCCCCBCDDDCDCDDDDDDDDDDDDDDDDDDDDB
@14H
CTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGG
+
@@@ABBADGHAHHGIJIIIIIIIGHHIHGIHEHE@FGGDHIIJD?BDFHGGGIJDDDFHIJJHEECEIIGHHGHHFCFCDDCEBEDDCDDCDCCBDDDDDD
@14I
CTCAAGAGTAATAATATATTTCTTCATGAAGACCTCACAGTAAAAATAGGTGATTTTGGTCTAGCTACAGTGAAATCTCGATGGAGTGGGTCCCATCAGTT
+
CCCFFFFFFHGHGJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJBGIJIJIJJHIIJJJJJIJJIIIIJJIGJJJHHHHHFDFFBEDEDDDDDEE
@14J
GAAATCACTGTGCTAAAGGCGGCTTTGGCTGATGTTTTGAGGCGTCTTGCAATCTCTGAAGATCATGTGGCCTCAGTGAAAAAATCAGTCTCAAGTAAAGG
+
??=DD?2AC4AC4EEC@>@3C<?@DEI;??6BDE<??BD17B(55-5?33);@3>(.66@6(;3>((5>A?2595>A:(;((29>>:>>4>ADAAA>>>3:
@14K
AAATGGATGGCAATTGAATCCCTTTTTGATCATATCTACACCACGCAAAGTGATGTATGGTCTTTTGGTGTCCTGCTGTGGGAGATCGTGACCCTAGGGGG
+
CCCFFFFFHHFHHJJIIJJJJJJJJJJJJJJJJIJJJIJIIGGIJJJIJJCFGGI=FGIJHIJJJJJIAEHGFFFFFFECCDBBBDCB9ACDDDDDDDDDD
@14L
CCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCT
+
BCCDFFFFGGHHHJJIIJJJJJJIJJICFHIJJJJJGGIJJJJIJGIBFHIJIIIGIJIJJJJJJJHHHHGFFFFFDEEEEEDDDDDCDDDDDDDDDBDC
@14M
CTTCTCCCCAGCCCTCTTCACAACCTCTCCAAATACACAGACAAACTCCAGAAAGCAAGAATGCTACTCCCACCAAAAGCATAAAACGACCATCACCAGCT
+
@@@:=D?D??BAFECEFEEHIFE=;9:CFCEDDGHFGGGGHIE?BD???B<FCFFGGCHGGGGG<7C3?EHADEDC;;@AC;>C;>3;B:=<:>44342(:
@14N
AAATCACTGTGCTAAAGGCGGCTTTGGCTGATGTTTTGAGGCGTCTTGCAATCTCTGAAGATCATGTGGCCTCAGTGAAAAAATCAGTCTCAAGTAAAGGC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJHJIIIJJIIJJJJJHHHHFFFFFFEEEEEEEDDDDDDDDDDDDDDDDDEDDDDDDDDDDDDEDDCCDCDDD
@14O
GGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGCAGGCATATG
+
CCCFFFFFHHHHHJJJJFIJJJJJJIJJJJJJJJJJIGIJJJJJJHIJJIJJIJJIIHHFFFDDDDDDDDDDDDDDDDEDDDDDDDDDDDDDDDDDDDDDE
@14P
TGCAATCTCTGAAGATCATGTGGCCTCAGCGAAAAAATCAGTCTCAAGTAAAGGCCAACCAAGCCCTCGAGCAGTTATTCCCATGTCCTGTATAACCAATG
+
@@@DDDFFHGHFHIIGGGGHGHGGIJJJIIIEAHIGFHGJHIGGGIGIJHIACEHGGIGGHHFHFEFEDDDDDDDDDECDDDCCCEDEDCDDEEEC@CDDC
@14Q
GTCATGCTTATATGGAGCAAAACTACTGTAGAGCCCACACCTGGGAAAGGACCTAAAGGTGTATATCAAATCAGCAAACAAATCAAAGCTCATGATGGC
+
@@@FFFFFFHHHGJJIEIEHGIJFIJIJ>FHIIJJJGCEGIIIIBFGIIIIHHGHEH>F8@@G>AHHJEHIHHHHHFFEFDCEDCEDCCCDDDDCCDAD
@14R
CAGCGTCCACTGCTGAAGACAGACATGGAACGTCACATCAACGAGGAGGACACAGTGCCTCTTTCTCACTTTGATGAGAGCATGGCCTACATGCCGGAAGG
+
CCCFFFFFHHHHGJJJJJJJJJJIGIJJIIJJJJJJJJJJJIHGIJJIJIIJJJIDHIHHHHHFFFFFFFEEEEDEEDDDBDCDDDDDCCDDCCDDDDDBD
@14S
GTTCATTCCTTCCGATGTTGACAACTATGATGACATCAGAACGGAACTGCCTCCTGAGAAGCTCAAACTGGAGTGGGCATATGGTTATCGAGGAAAGGACT
+
B@@DDDFDFHHFGJGIIEHJGIIIJHIJJIIIGHGIIIIJJEFDHGEIIGIJJIIJJGGIIEHJFIJDHHGEH7?DFDCECCDDDDDDDDBDDDDDBBBDC
@14T
CCCTCTGTCAGTGTCTCCCATGGAGAATAATCACTGCCCAGCGTCCTCCGAGTCCCACCCGAAGCCATCCAGCCCCCGGCAGGAGAGCACACGCGTGATCC
+
CCCFFFFFHHHHHIJJJJJJJIJIJJJJJJJJJJJJJIJJJIIJJJJJJJIJHJJJJJJJJHHFFFEEEEEDDDDDDDDDDDDDDBDDDBDDBDDBDDDED
@14U
GGACGAGGATACCTGTCTCCAGATCTCAGTAAGGTACGGAGTAACTGTCCAAAAGCCATGAAGAGATTAATGGCAGAGTGCCTCAAAAAGAAAAGAGATG
+
CCCDFDFFFHHHHEIIGHGFHIJIGIJJGGIFJI?FHIIHIBFHGIJBDHHGIJEIJJEGIHGJJEHHFFCEFDEBCD;A;@CCCDDDDDDBDCDDDD@A
@14V
CGACCAAAGACCTACTTTGCATAGAATTCAGGACCAACTTCAGTTATTCAGAAATTTTTTTCTTAAATAGCATTTATAAGTCCAGAGATGAAGCAAACAAC
+
>;=;<0<A@++27<7A==+<?=?C2?A4+2?A*1?==?AAB9?0?A*=*=47A<?<<<<66>=AAA33=>3>@B3>>>.>>3;>=(;(;=??:9==>===9
@14W
AATACCTTCAACACCCAAATTAATACCAAAAGTTACCAAAACTGCAGACAAGCATAAAGATGTCATCATCAACCAAGAAGGAGAATATATTAAAATGTTT
+
@@CFFFFFHHHHHJJJIJJJJJJIJJJJIJJJHHJJIJJJJJJJJJJJJJJJJJJJJJIJIJGIJJIJJIJJFHHHFFFFFDDDCCDEEEEFEDDDDBCD
@14X
CCGAGTTGCAGTCCTGGAAAATCAAAATAAAACTCTAATAGAAGAGTTAAAAACTTTGAAGGATCTTTATTCCAATAAAAGTGTTTGATTCCTAAGAA
+
@CCFFDFFHHHHFJJJJJJJJJJJJJJJJJJJJJJJIIJJJJIJJJJIJJJJJJJJJJJJJJIJJJJJJJJJJJJIIJHHHCHHEFFFFFEEEEEEED
@14Y
AAGAAAAGCACAAAAGGAAAGAGGAAGTGGAAGAGAATAAAAAAAGCAAAGCCAAGGAACCTCCTCCTAAAAAGACGAAGAAAAATAATAGCAGCAACAGC
+
CCCFFFFFGGHHHIIJIIJIJIIJJJI?FGEIHGHHIJJJJJJIGJJJIJIIJJIGGHHFFFFDEEEEDDDDDDDDDDBDDDDDDDDDDEDDDDBDDDDDD
@14Z
CCTGTATACCGGATAATGACTCAGTGCTGGCAACATCAGCCTGAAGACAGGCCCAACTTTGCAATCATTTTGGAGAGGATTGAATACTGCACCCAGGACCC
+
=+=D1BBDABCFDE<<AD<+<ABG<A<+:::1:8C?CGEE9BF?BDE?DF?;<FFICF>DDE)=47=)7=);<);65;(5;?;@;;5(5(,((,8????B?
@150
CAGCAAATTCAACCACCAGAACATTGTTCGCTGCATTGGGGTGAGCCTGCAATCCCTGCCCCGGTTCATCCTGCTGGAGCTCATGGCGGGGGGGGGCCTC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJIJJJJJJJJJJJFHJJJJJJIJJJJJJJJHHHFFDDDDDEEDDDDDDDDDDDDDDDDDDDBDDD@B&&)(+
@151
ATAATATATTTCTTCATGAAGACCTCACAGTAAAAATAGGTGATTTTGGTCTAGCTACAGTGAAATCTCGATGGAGTGGGTCCCATCAGTTTGAACAGTTG
+
?<@B?BDDFBHH?GGCHEGHG@DFH>G:CHHGHIDG@CHCC??DHIGGBFHGCG>GHIIE4?FHEABBCFEFII<D@EHF5?B>CCCCC33;;@C;@?;5@
@152
GGGAAAGCGAGAGGGAGACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGG
+
@@@BDDADHDDAABHGGEGG@:CF?FEEGGGIE>AFHB<DGEHHFFFD;=CCC@C@BB8?=@C<@>7@CACC:@CCCCCCDCCCCCC@:>?CC@@B>B@BB
@153
TGCAGAGGCGCCTCCAAGTTTCAGTGGCGCTCAGTTGGACTCAAGTCCTTCTGGTTCTGTTGAGGATGAAGATGGGGATGGGCGGCTTCGGCCCTCACCTG
+
;??BBBDD?HDD@@?EEA?<?EGGDD@?DGI6DBFFE?FHA==8@.@==;E;EHGEHA;?=.;@@;BC@>C;>5;?B5'58,(;59B93535<><8<<A:?
@154
CTGGCTCACTAACTAACGTGAAAGCCTTACAGAAATCTCCAGGACCTCAGCGAGAAAGGAAGTCATCTTCATCCTCAGAAGACAGGAATCGAATGAAAAC
+
CCCFFFFFHHHHGJJJJJGIIJJJJJJJJJJJJJJJJJJJJJJJJJIJIJIJGGJJJJJJJJHHHHGHHHFFFFFFEEEEECDDDDDDDDDDDDDDDDDD
@155
TTAGAACAGCTCCAAGAAGAAACATTCAGACTAGAAGCAGCCAAAGATGATTATCGAATACGTTGTGAAGAGTTAGAAAAGGAGATCTCTGAACTTCGGC
+
C@CFFFFFHHHHHJJJIIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJIJJCHJJIFHEHGHFFFFFDCDDEDEDEDDDCDDDDDD
@156
CTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHFFDEEEEDDDDDDDDDDDDDDDDDDDDDDDDDDAC
@157
AGATCATCGAAATCAATTTGGGCAACGAGACCGATCCTCATCAGCTCCCAATGTGCATATAAACACAATAGAACCTGTCAATATTGATGACTTGATTAG
+
@@@DDDDDFDHFBG?FGIGGGIIGIIBGIIIIIIGGHGBIIIIIICHIGGHIHEEHDHEEEEEEECACCCCCCC@C?CCCDDCACD@>ADCCC:ACCDC
@158
GCCACTGAAAATCAAGAAAGAACCCCACAGTCCATGTTCAGAAATCAGCTCTGCCTGCAGTCAAGAACAGCCCTTTAAATTCAGCTATGGAGAAAAGTGCC
+
@<@FFFFDHHHHDGJIIIJJIJJIIIIGJJFEHIIJHGIJGIJJJIGCGDHGIIJGJIJIGIGJJGGIFGGEHHFFFFFFDCECEDCDDDDDDDDDDDDDD
@159
CCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGT
+
CCCFFFFFDFDHGEHGIDHGIIJJIIEGGIJJIEGBFIDGGFCFHG>FGJHJGIGGHIGGFAEHGHFFEBCEEDDEDEEEEEDDDBDDBDDBDDBB??:
@15A
GAATGGCAAAGCTCTCCTGCTGCTGACCAAAGAGGACTTTCGCTATCGATCTCCTCATTCAGGTGATGTGCTCTATGAACTCCTTCAGCATATTCTGAAGC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJIJJJJJJJJJIJJJJJIJJIIIIJJJJJIIJJIGJJJ@EHHHCEFHHFFFFFFEEEEEDEDDDDDDDEEEEEDDD
@15B
CCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJIIJJJJJJJJJDFFFEEEDDDDDDDDDDDDDDDDDDDDDDDDDD@CDDEDDDDCC
@15C
GTGTATATCAAATCAGCAAACAAATCAAAGCTCATGATGGCAGTGTGTTCACACTTTGTCAGATGAGAAATGGGATGTTATTAACTGGAGGAGGGAAAGAC
+
<@@BDDFDFFFFHGAFGFHGIGBHEFHEHGEHDIGECEHGIEG;??B?DCDHGEIIHF?F@FCGF8==FHDAG;;DECC:ACF@;;@CAAB?@@B69?<:<
@15D
GCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGT
+
???D?B?BBBFDHGIBCF?8@FAFEC:C??@@C@D>FG<;BBGFF>AFA4BBDHBBFF@=C@C>CC>CHED<<A;???CCCC@C@@BCB?8>ACC<>A@C4
@15E
GTTACCTATGGGACTGAAGGACTGCAGCAGTTACAAGAATTTGAAGCTGCCATTAAACAAAGAGATGGCATTATAACCCAGCTCACTGCTAATTTACAAC
+
@@@FFFFFHHHHHJJJJJJJJJJJJJJJJJGIIJJJJIJJCHIJJIIIIJJJJIJJJJIJJJIICGHIIJJEEEHHFGFFFFEEEEEEDDDDDEEDEDDD
@15F
CAAACTGCATCAGGAGATATGCAAACATATCAGATCCGAACTACACCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATGACATCTCCTGTGACTCTCAC
+
CCCFFFFFHHHHHJJJIJJJJJIJIJJIJJJJJJJJJJIJIJJJJJJJJJJJJJJJJJIJJJJJJJJJJIFHHHHHBDFFFEEEEDDDDDDDDEDDDDDDD
@15G
ATTCACTAACAAGAAAACAGGGAATTTTTGGGAAATATGAAAAGCCAAAATTTGTGCAGTGTTTAGCATTCTTGGGGAATGGAGATGTTCTTACTGGAGAC
+
C@CFFFFFHHGHHIIIIJJJIJIJJIIIJIJGJJJIIJIHGHJHIJJIFHIJJGFHGIIFDFHIIGIGHFEHFHHFFFDEEDCDDDCEDEEDDDDDCDDCD
@15H
TCGCAGTCCATACCAGATAGCAGCTACCCCATGGACCACAGATTTCGCCGCCAGCTTTCTGAACCCTGTAACTCCTTTCCTCCTTTGCCGACGATGCCA
+
CCCFFFDFHGGGHJGJIIIJJJJJJJJJIJJJJJJJIIJJIIJJJJJJJJJJJJHHHGHHFFFFFDEEEEEDEDDDDDDDDDDDDDDDDDDDDDDDDDD
@15I
CCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCAC
+
CCCFFFFFHGHHDIIIJJJJIJJJJJJJIGIJIJJJGIJGIIIJIJJJJHJJIIJEIIJIIIJJJFDHFFFFECCEECEECDCDEDDCCDDDDDDDDDDDD
@15J
CTGCCAGGGACTGGGCTCCAGGGGCAACATTTCCCTGGGTCCTGGAGAAACCCTAGTACCTGGGGATACGGAGAGCAGTGTGATTCCCTGTGGAGGCAC
+
8=8BDDDD:<?F?D?E:ACFCFA1?CGGD39DDF99?2)0?@BCCE;)BFF(5.@37.7??)6;4?>(6??BB>?<A@BA,,:;;@:>4++:3++228?
@15K
AGACAACAAATGAAGTTGTTTTGGCTGTGGAGGTTCACCCAACAGATGCAAATACCATAATTACATGCGGTAAATCTCATATTTTCTTCTGGACCTGGAGC
+
@@@DDBBD=DHHFIIB9CABGGEF3CB?FECG):;?BBDDD@1DE@<D49B44BB@DAGEIII7CHG;=B,9?CCCCCCDCDDDE5@>CCCC:53?CB?B?
@15L
CCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCAC
+
1==A++<?A+7A3+?ABABCCB@CBB?0A<1:?7?4**;9;A=A<ABBBBABABB>;).=4)=>A5==1=@@>>5;..>((5=;;;;>?=8(5(5:>,+(+
@15M
CAGCAAACAAATCAAAGCTCATGATGGCAGTGTGTTCACACTTTGTCAGATGAGAAATGGGATGTTATTAACTGGAGGAGGGAAAGACAGAAAAATAATTC
+
@@@=DDD8FFHDFEHGHFD9DEC<BEHHFGCE?EBF@DH@GEGGF<BDBHII?BDGGCFGGG@F@F@FCHEHHIG=AC(;93=;A=?;AACCC??<@CDD;
@15N
GTTTCGCCGGCAGTCTCGATGATAGTATTTCTGCTGCAAGTACTTCTGATGTTCAAGATCGCCTGTCAGCTCTTGAGTCACGAGTTCAGCAACAAGA
+
@@@DDDFFAAFH<FEDEHIGHCDHEHCGCDHCFG<FAFDD8BFDCHGGDG@=@=CGED;=@?EHEFFDBC@>AC@CA5@CCB?@8?>CACCDBBACC
@15O
ACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACT
+
CCCFFFFFHGGHHJJIJJFIIJJJIJJJGJJJJIIJJJIIGIGIGIIGGIJJJIJIIICIGIIJIJHFHHHHFFFDDDDDDCDEEDDDDCDDD9ACCDDDC
@15P
CCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATG
+
CCCFFFFFHHHGHJJJJJJJJJJJIJJJJJJHHIJJJJJJJJJJJJJJJIJJJJJIIJJJJJIHHHFFFFEEEEEEEEDDDDDDDDDDDDDDDDDDDDCED
@15Q
GCTTCCACTTCGGGCGGGGGAGCCCCGGACCGAATCGGCTCTCTAGGCCGTGGAGCTTGCCGTCCCACCTCCGTCCAAATCGACCTTTCCTTTCTATCCCC
+
<?@DBDDFFFDHFHJGGIED6=BBDDD63:BDD@BD?BDBBA>>>CC8CBBBDB?ABD?8(005@BDD@@<<@8?@@>@CCD?0)0:>>CC>C::::A?C@
@15R
GTTCATTCCTTCCGATGTTGACAACTATGATGACATCAGAACGGAACTGCCTCCTGAGAAGCTCAAACTGGAGTGGGCATATGGTTATCGAGGAAAGGACT
+
??@DFFFDHDHHFHEGGHHFHHIDEGGIICHGGBHICF>?FHDABFAHGAGCHCHEHGEG@;D=@GHHHGF3A7;?D56>3@DC5;;>CA?@@B@CDB8AA
@15S
TGGCAAAGCTCTCCTGCTGCTGACCAAAGAGGACTTTCGCTATCGATCTCCTCATTCAGGTGATGTGCTCTATGAACTCCTTCAGCATATTCTGAAGC
+
:11ADDDDDDD<:2+2<:3<<<F339AF9E??EB9??D6):60??B8(/=8..B8==@7/@77).@@777?=;)...?;;66@;(.;(>A;BD>((,>
@15T
TGATCTTTCTGAACAATTGAAACAGAAACATGGTGAGATTAGTTTTCTAAATGAAGAAGTTAAATCTTTAAAGCAAGAGAAAGAACAAGTTTCATTG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJFHHJIJIIJIIJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJIJJHHHHHFFFFFEEEEEEE
@15U
GCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCC
+
@@@DDBDDDB<DFEDEAG;CCE@HEDHEEFHGGGGG>DHBBFDDFCHDEEHIIIGCFFHGIGGGDGGGEE>ADDE??B=@CCACCC@CC@>ABAC8?:@>
@15V
TAATGAATGTGGCAATAAATGAACTGAATATAAAATTGCAAGATACTAACTCTCAAAAGGAAAAACTCAAGGAAGAACTAGGACTAATTTTAGAAGAAA
+
@C@FFDDEHDHGFHIIEHGHIIJJIJIIIJIJJJGFGIJIHHBDGIDIIJIIIGHIGIIJIIIIIIJJJJJGIJIIHHHHHFDEFFDEEEDDDCDCCCD
@15W
ATTTGAAAAAGCGATAGGGAAGACTCTGCCATGAATAATGTCAAATTGAGATTGGTTGTTGGAAGCATAAGTATATCGGTACTGCGACAAAGCTGTTTCGG
+
7;<(2)229((2((2(8)3.95(2)):))2:)2):;))).))0.)0=8)30)))()(-'.67))8().6;).8).).53(.'7(-'98''(,+(++(+(+-
@15X
TGGAGTTTCACCCAACAGATGCAAATACCATAATTACATGTGGTAAATCTCATATTTTCTTCTGGACCTGGAGCGGCAATTCACTAACAAGAAAACAGGG
+
?@@D=2B:CFDFFDF?E?C+<BAH?F?9CC>?EGII>DFF??D9BGF@GDBF??DEGC<9?BAC@FAF@ECE;CAEBCCA@>AABAABBBB?B@@5<??B
@15Y
CACCTAACGTTGCAACTGGGAGACTTCCGGGGGCCTCACTGCTCCTAGAGCCCTCTTCGCTGACTGCCAATATGAAGGAGGTACCTCTGTTCAGGCTACGT
+
C@BFFFFFGHHHHJJIJIJJJJIIJJJJJJJIJIJGGHHHFFEFFEECECCDDDDDCDADDBDDDDDDDDDDDEEEDDDDD?CCDDDDDCCDEDDDDDDDA
@15Z
AGGCAGGGTGGATCCTGATCTGTCCAAGCCTAAAAACCTTGCTCCTTTACAAGAGAGTCAGGAGTCTTACACAACTGGGACTCCCAAAGCAACATCTTCTC
+
;=8D;D:?C:)A+2A<:2CEBF<CC<918C?C9C*0@B?9D9?D8DB@?B=8.B28@.@77@);)=7=A@>A>;=666>(,5>><5>5=9::,,34>>>>>
@160
TGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGG
+
CCCFFFFFHHGHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJHIJJJJHHHHFFFDDEDEDDDDDDDDDDDDDDDDDDDEDDDDEDDEDDDDDDD
@161
CTTAAAACAGAATTGTTAGAAAAACAGATGAAGGAAAAAGAGAATGATCTTCAAGAAAAATTTGCACAACTTGAAGCAGAGAATAGCATTCTTAAAGATG
+
CCCFFFFFGGHHHJIIIJJJJJIIJJJGGJIIIIJJJJJJJJJIJJIIJJJJJJJJJJJJIJJJJJ3CHGIHHHHHHFFFFEECEECDEDDEEDEDDDDD
@162
CTGATGACTCTGAGGAGGAGCGAGCCCAGCGGCTGGCTGAGCTCCAGGAGCAGCTCAAAGCCGTGCACGAGCAGCTTGCAGCCCTCTCTCAGCCCCAGC
+
CCCFFFFFHHHHGJJJJGIJGGJIIJJJIJGHHGGEHIIGIJCGHHFHFFFDCC>CCEDCCDB@BDBDBDBBBDDDDDBDDDDDCB?CACD@ACDD??B
@163
CTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCT
+
@@?BB3BDFFF>DAEGFG?EFHBEHG@GGHD>?@GGI@DHIGEG@GBGGICB;BFGGGHIHHCHGGG>A@EHE>9>>@CC@CD>A>@>>:@>ACCCCCC:4
@164
CACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGC
+
@?=?DDEDBFFFHB@FGGGGBE@CGHGI?DGGIIDHFIEIHDHIE@DA3;FGEGCFFHCD7@DCHHEEEEFFD=D<>@ACCCBCBCCCC@CBACCCCB?
@165
GCCAGATGTCTGAGCCAAACATCCCCTTCCCACCACAAGGCTTTAAGCAGGAGTACCACGACCCAGTGTATGAACACAACACCATGGTTGGCAGCGCGGCC
+
+=@DD;BB=DF8CE9CFFFECH<3CGFF@FFIC?CGEIIFI99BBGC8?F?1<8.78CC5A84:??.7(.;;.>;>?@B?@1,(:(5,:?>+(2(05@>BB
@166
ACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGT
+
@@@FFDDDFHDHDIBEEGFGHIIGICGIIIIJJIJHIIJIIIJGIHGGGGGHIIEIIIGIGIIIHJJEHHFFFFFFDECEEEEDDDCD>CCDDB?;<BDCD
@167
GAAAACTCTTGAGCTAAAGGATAAATTAACAACTGCTGATAAATTACTAGGAGAATTACAAGAACAGATTGTGCAAAAGAACCAAGAAATAAAAAACATG
+
@@CFFFFFGFDAFHGIIIJJJIIIGIJIDFHIIIIEHIJIHIIJIIGHHIEDHGHGDGFJIEHJDIIGGHIDGIHIJHGEECBDEFEDDDEC@CDDDBDD
@168
GTAAAAGATGATTTAGAAGACAGTAAAAATAAACAGGAATTAGAGTATAAAAGTAAACTTAAAGCACTTAATGAAGAGCTTCATTTGCAAAGAATAAATCC
+
@?@DDFFDHHHFHIIBFHHGGIIGEEHIGDAHHIJIGGHIIJIIGGGEHIHCF9BGCHGEGIJEGEGGIJGHDHICDAH>>EHHHFFFDDECCEEDEEEC@
@169
ATCAACCCCACCCCGCAATCCTGCAGCATTCGACGCACGACCCATCCCAGTCGATTATACATAAAAAACCATCATACCCCCTACATAACTTTAAGAATGC
+
0(0@@?>;;8-:(((<1(@)=).13))()))))0(-9/;=5-'().(.((..'(6(,(,72(,((((&&+2((+((+((+)5-(2+3:((((+((+8(((
@16A
GGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACAC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJHIJJJJJJIJJJJJJJJJJJJJJJJJJIJJJJIJJJJJJJHHHHHFFFFFDDEEDDDDDDDDDEEDDDDDDD
@16B
GAAAATTTTAAAAGGAATCTTGGATTATAATCATGAGATTTTAGGACAGCAAATTAATGACTTTACCCTTCCTGATGTGAACCTTATTGGGGAGCATTCTG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIIGGHHHHHFEFFFFDDDDDDDDDEE
@16C
GAAATCTCCAGGACCTCAGCGAGAAAGGAAGTCATCTTCATCCTCAGAAGACAGGAATCGAATGAAAACACTTGGTAGACGGGACTCGAGTGATGATTGGG
+
C@CFFFFFHHHHHJJJJJIJJJJJJJJJIJJHIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHHHFFFFFDEEEEDDDBDDDDDDAACDDEEEDDD
@16D
ATCCCTTTTTGATCATATCTACACCACGAAAAGTGATGTATGGTCTTTTGGTGTCCTGCTGTGGGAGATCGTGACCCTAGGGGGAAACCCCTATCCTGGG
+
@;?BBB?;?:DD?F<EGBH@DHIEFCEE)1?@B?FDBD99?BB0?<FAFEFBFF=4)@3@FFFEIEA/)=B3??BAB>@=A=?BB7??@B<??:AB3:><
@16E
CCCAAGTCGCTGGTATCCGTCATCGTAGGCAGGCAATATATTCAAGCGAAAGCAGGACTAGCCGATGCCGCAAAGTGCTGAGGAGGGGGAGCAGCAATTTG
+
((0;(())2(--(:))..(-.38))(6-51)8(-0()..9><>)))9(;''';.).-())))),','((3''''((+((5+((+8508&08-((+((((((
@16F
CGCCTAGAGGGAAAGCGAGAGGGAGACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGC
+
=?=?ADD?HFD:DFBGH;C??FHAGDGGEFDH@FF<FHIDGIGAEE6BE;>ABBB?BBCC?CCCBB7@BBC?B9@@CCCC>@ACCACC@@CCCB?@ACCCC
@16G
CCTTGCTATACATCCTGACAAAATTAGGATTGCAACTGGACAGATAGCTGGCGTGGATAAAGATGGAAGGCCTCTACAACCCCACGTCAGAGTGTGGGATT
+
@@BFFFFFHHHHHJJJIBCHHIJHIHIJGGIJJJJIIIIIIJJGGIJJJJJIGFHIGIIJJJIJIGIHHHGFFFFFFEEEDDD@DB?BBDCC:ACCDDBDD
@16H
CAGCGTCCACTGCTGAAGACAGACATGGAACGTCACATCAACGAGGAGGACACAGTGCCTCTTTCTCACTTTGATGAGAGCATGGCCTACATGCCGGAAGG
+
CCCFFFFFHHHHGJJJIJJJJJJIIJJIJJJJJJIJIJJIJJIJJJIJJIIIJJICGIHHHHHFFFEFFFEEEEDCEDCDDDDDDDDDDDDDDDDDDDDDD
@16I
CTCAAAAGGAAAAACTCAAGGAAGAACTAGGACTAATTTTAGAAGAAAAGTGTGCTCTACAGAGACAGCTTGAAGACCTTGTTGAAGAATTGAGCTTTTC
+
CCCFFFFFHGHHHJJJJJJJJJJJHIJJJIJJIJJJJJIJJJJJJJIJJJFHIHJJIJJIJIJIJJJIJJJHHHHHFFFFFFEEEEEEDDDDDDDDDDDD
@16J
AACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCC
+
CCCFFDFFHHHHHIJJGEHIJIJJJJJIJEFHIGIJJJBHGJJJJIGGG?FHG@GGGCFHIIJIIEHFHHHFFFEECC>C;@AACCDBDDCDDCCCDDCDD
@16K
GGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGC
+
?@:DDDDDHFHFHIGGGGDEGGHIGGEEFFHIGGGGIIFGHIGGIGIIGGGGIIIDHIIGIIHHFFHEEEECCCCCC>>CCDCCACCCCCBBBCCCCCB
@16L
TGAGGAGAGAACTCAGCGACACTACCTGGGCCATACAGACTGTGTGAAATGCCTTGCTATACATCCTGACAAAATTAGGATTGCAACTGGACAGATAGCTG
+
CC@FFFFFHFHHGHJJIJBIGIJJJJJJIJJJJJJJJIIJJJIJGIIIJGIJJHIJIJJJJIHHHFHHFFFFFDEEECECDDDCCDDDDDDDDDDDDDDDD
@16M
TGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTAC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJHIIJJJJJIDGHJIJJJGIJJJJJJJJJJJJHHHHFFFFDEEEEDDEEDDDDDDDDDDDDDDDDDDDDDD
@16N
CCCCCTCCCACGTATGAGTCGGAGGAAGAGGACAAGTGCAAGCCTATGTCCTATGAGGAGAAGCGGCAGCTCAGCTTGGACATCAACAAGCTCCCCGGCG
+
CCCFFFFFHHHHFIJJIIEHIIGHJIJJIJJJJIJIJIIJJIJJJJJJJJGJIJJIJHHHHFFFFDDDDDCDDDCCDDDDDDDDDDDDDDDDDDDDBDBB
@16O
CTGCACGCAGCCCAAATCCCCATCCAGCACGTCAGTGTCCCCACTGCATCATGCATCTCCAAACTCAACTCATACACCGAAACCTGACCGGGCCTTCCC
+
@@8DBDDDF?@C<AFEB9EG?FIBFFDD@FI?BDG9?9BF8BFAFDF===CFD@;CE@A>DF@CEEDDD@DCCAAAABBBBB@<??BBB@>B@B@@>BB
@16P
CCTCCTCTGATGATTAAACAGGAACCCAGAGATTTTGCATATGACTCAGAAGTGCCTAGCTGCCACTCCATTTATATGAGGCAAGAAGGCTTCCTGGCTC
+
<@@DD;=DCFDDDBFFGF3C?;E;BGHIGI):??B>B@DC9BDDF<FADGHG*?*9BFBDCCHB:F>GHAEDCEEAA;=A95;((6;>(;33(--;9935
@16Q
CTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJIJJJJJJIJJJJJJJJJIJJJJJJJJJJJJJJJJHHHHFFFCDFEEEEEEEDDDDDDDDCDDDDDDDDD
@16R
AAACAAACTCTATGGCATGTCAGACCCGAACTGGCCTGGAGAGAGTCCTGTACCACTCACGAGAGCTGATGGCACTAACACTGGGTTTCCAAGATATCCA
+
BCCFFFFFGHHHHJJJIJIJJJJIIJJIJJJIGIHIIJJIIGGGGHGIJIGGIIIIJGEEHFFHEFFFCECE@>CCCDCCDCDDD<?BACCDDBACEDEC
@16S
ACTTGTGCCCAGCAATCAGGTGGTCGTACAAACTGCATCAGGAGATATGCAAACATATCAGATCCGAACTACACCTTCAGCTACTTCTCTGCCACAAACTG
+
CCCFFFFFHHHHHJJJJJJJHHIGHJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHFFFFFEEEEEEDDDDDDDDDDDDDDDDDDDDD
@16T
GTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGC
+
@@@BFFF?FBBFHGIJHGIGIIGIGGCEFCHEGIIIJIHGGHIIJGE>GHAEGCEHJEIGECHHAEEHFFFFFFED3>CEDCDDA?ACACCCDCDDCBD
@16U
GTCAGCACACCATGATTTGAATATTGATCAATCACAGTGTAATGAAATGTACATAAATAGTTCTCAGAGAGTAGAATCAACTGTGATTCCTGAATCTACA
+
C@CFFFFFHHHGHJJJJJJJJJJJJIJIGHCHHGJJIGJEDFIGIIIJJFIIJIHJIIGIHGIIJIJJJJJIICFHHGIIIII=EEHHEHHFFFFFFDEE
@16V
CCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAAC
+
@@@DD;++=AC;::;EFFEFCEF@E<BG<BF>FADGFDGFIIBBF(==5=@@A@67?E?BDB;366>A@A5@BA5<B@AB>A>(:@::99<?<05<24>AB
@16W
ATGACACCTGTGTTGTCCCAGAAAAATTCGATGGAGACATCAAACAAGAGCCAGGAATGTATCGGGAAGGACCCACATACCAACGGCGAGGATCACTTC
+
@@CFDAEAFFFDHEEDHGIIEECG?@EHGG@GHIIGEHGCIIIIIIEIC?DEHAHIIEGFGGCEGBAB5;@>;=CB@ACCCCCBBBBB9@B7ACC3:>@
@16X
CTCTTTCATCTGCTGCTAAAAGTGGGACAGAAAAAAAGAAAGAAAAACCACAAGGACAGAGAGAAAAAAAAGAGGAATCTCATTCTAATGATTAAAGACC
+
==1?AA,,?ACB<,++<A>BB@<++3<7A<+::@BA=0)9><*>BBBA;21=B(==>A<=);(5>;>@::75889198(+83(53(+:8838(3:;(((3
@16Y
GAAACCTAGTGCCGCCCTGTCTCCATCCCCTGCACTTCCCTTTCTCCGACCAACTTCTGACCCACCAGACCACCCACCCAGGGAGCCACCTCCACAGCCC
+
=7==AA3A7<=@<A))?A@<A47@*:??A<>))0??AA39777?B4='-='-(;77=)7>).(.5=2;;==;==:582729(&(5;=(89(22(+8+9<<
@16Z
AGAGGGAAAGCGAGAGGGAGACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGC
+
@C@FFFFFHHHHHIJJJJHIGIJJJJJJJJJJJJIIIJGIIHHHDFDFADDD@DDDCDDDDDDDBDDDBBDDDDDDEDDDDDDEDDDDDBDDDDDDDDDDD
@170
GGAGAAGCGGCAGCTCAGCTTGGACATCAACAAGCTCCCCGGCGAGAAGCTGGGCCGCGTGGTGCACATCATCCAGTCACGGGAGCCCTCCCTGAAGAATT
+
CC@FFFFFHHHGHJIJJJIIJJJJIJJJJJJJJJJIJJJJJJIHFDDDDDDDDDDDDDDBDD<@CCCDDDDDDDDDDDDDDDDDDDDDCDDDDDDDDCDCD
@171
GCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGC
+
@@@D;DDDFFHDHG>FFAAHCFE><F>F>D?BGDDGI9FHGA9?GGIHB?DF@CF/@ABEHEEEDC>@CC?B?2=<>3>::@:ACCD3:2>CC>:C>AC@
@172
TTGAAAGCTGAGATTGTTTCTGCATCTGAATCCAGAAAGGAACTAGAATTAAAACATGAAGCAGAAGTTACAAATTACAAGATAAAACTTGAAATGTT
+
CCCFFFFFHHHHGJJJJJJIJJJJJJJJJGIIIGHHJJJJIIJGJJIEGIJJJJIIIJHGIIIJJGHIJJJIJGIJJHHHHHHFFFFFFDECCEEDFD
@173
CCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTG
+
??8=BDBDBDD8AEE?+<F:AEAAF;181??9:8B<B;909<9?B@D*0/=B@CBAD@EII<7.==;??>3??=6=<;;?=?A25=>:A>5>>5449:>3>
@174
CAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTAC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJIJIJIIIJJJJJIJJJJJJJJJJJIJJJJJHHFBBDDDDDDDDDDDDBBDDDDDDDDDDDDDDBDD@CDDEDD
@175
CACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACC
+
@@@FFDEFHHHGHIJIJJJGGGHIHGIIHGGIIJJIJGIIJJJJI?FHIJIHGGCHGIHICHGIIJHHHFHFDFDDBDDBDBCBADCDDDCDC<BBBDBBD
@176
CTATTTTCTTATTTTCACAGTATAAGAAAATACCTACTTAAGATTCATTTGGAGGCATGTCTAAATCTAGTAATTTATTAGAAGCTTATCCATCCCTATT
+
C@CFFFFFHHHHHJJIIIIJIJJJJJJJJJJJJIJIIJJIJJGHHHGIIJJJJFGIIJJGIIIJJGGGJIIIGIGEHIJJIIJJJHHHGHGFFCDFEEEE
@177
CCTGTCCCCCCTACTATTCTCCCACTTGTTATACTACTCCAACTGCCCCCCGGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACC
+
<9;;@)=)(((((.)).))6.:))1<)9=>?=):>:><?<19<7=<<>535''9=<;:;5=(35;52;<<03::/89&)383(369<<55::<=(5(8555
@178
CCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCC
+
>==A1AAA=7+<+@=CCCA@A;ABACA<=<<5=?=AABB==?==AABBBBA<8A=7>>BBBBAB;).=>AAAA;.7?>@;@@>@?=?===========;99
@179
TCTGGATCATTTGGAACAGTCTACAAGGGAAAGTGGCATGGTGATGTGGCAGTGAAAATGTTGAATGTGACAGCACCTACACCTCAGCAGTTACAAGCCTT
+
CCCFFFFFHHHHGJHJJJJJJIJJJJJJJJJJJFIIIJIJJ?DDHHIIIIHIGGGIJJIGGIIIJJIIGJIIIIEHHHHFFFFBAEEEDDCCCDCDCBDDD
@17A
TATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTT
+
CCCFFFFFHHHHHJJJJJJIJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJIIJJJJJJJJJHHFFDEEEEEDDDDDDDDDDDDDDDDDDDDDDDDD@C
@17B
CTGTGTCCAGAGGACCCCCAGGCCATCCGTGGATAATGTGCACCATAACCCTCCCACCATTGAACTGTTGCACCGCTCCAGGTCACCTATCACGACAAATC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJIJJFIJJJIHIIJJJJJJJJJJJJJJIJJHHHHHHFFFFFFEEEEDDDDDDDDCDDDDDDDDDDDDDD@CCD
@17C
CAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCAC
+
@@;DDEFFFFFFAEGGIGGIAEGGH@GHIGCHCAFHIIEDGIIIIGGHIIIIIIEHIII@C?CEEEFE?CDE>@AE(;ADDCDAC>A<CBDB?<AACBB?B
@17D
CAGCAGAACAGAAGGCTGTATGTTTGAAAAGGGCCCCAGGCAGTTTTATGATGACACCTGTGTTGTCCCAGAAAAATTCGATGGAGACATCAAACAAGAGC
+
CCCFFFFFFHFHHIJIJJJIJJJIIJHIJJGIJJJJJJJJIJJFHIGGIJHIJJIDGHIIGHJIGEHHHGFFFFFEEEEDCDDDDDDDDCDDDDDDDDDDD
@17E
CGAGCAGCTTGCAGCCCTCTCTCAGCCCCAGCAGAACAAACCAAAGAAAAAGGAGAAAGACAAGAAGGAAAAGAAAAAAGAAAAGCACAAAAGGAAAGAGG
+
??=A?8A;DA?BDE+:E:C:FCFBEEEEE;?D;DBD)9)?8B??/9=.B8=AA@CACCD>C9>@DDDA@AAAA?>;=;38<=??A?A>3+823<(>9<9><
@17F
GATAGTATTTCTGCTGCAAGTACTTCTGATGTTCAAGATCGCCTGTCAGCTCTTGAGTCACGAGTTCAGCAACAAGAAGATGAAATCACTGTGCTAAAGGC
+
??@DBADDHFHFHIGI<DAHHHBHIA>EED>HHAHGGHGCEHIGIEHHIIEEEIGI@BB<F6;;;@=;=;=AEHHF?>?DEEDDE@C@@>@C>C@ACCCCA
@17G
TACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGC
+
@@@DDFDAHA<DHFGDGBHGDBBGGEDEGGGHIGIGGIIFGGGII@FE?DH@B=@FCHGIIAEBBDECC@CECCCC?CBCB>A>CCDCCCCCCCCCCC9<
@17H
CGGTCAGGGATAAATTATAGGGGGCTTGTTACAGGTTCTGGGCAGGGAGAAGAAAAGTCTGAGGGTTCACTAGGCACGCAGGGAAAGGAATAGGGGGGTTT
+
0-(((())(())).)2494))3<(((1((.)6)39..).98)()-'3(-'()).)..))).(./=((,--(((,(((,')&&)8(((2(+((((+&&))&(
@17I
CTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGC
+
=?@B;BDFHHHBDGGHBGEHEGHIEGHFEHG<EG?@AGH@DFEFHCAFG@<CCBFHIIAE@HIGHGI>?>?CDC@C@@BA>;A;;=@=@CBCCC@CCCCBB
@17J
GGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTAC
+
?@@AD;DDADDF?:CGHF?@BCE@@HHFCGHEHGE@DC<@:7F=FBHGFCGIGCH;AEHEDE>BC?'35>CBCCCCB,9CC@CACCC:@CCCBABCCCCCC
@17K
GGCTCATCCCAGCAGAACAGAAGGCTGTATGTTTGAAAAGGGCCCCAGGCAGTTTTATGATGACACCTGTGTTGTCCCAGAAAAATTCGATGGAGACATC
+
@@@D?D??FBDFHEBFHEG@BAAGGDDCGGFCEF;CGFFHBFHHIGBFGFGG@CHHGEE@ECACGAA?AEEEB=CC@CACCCAC==A>?;>CB??>B?CC
@17L
CAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHIJJJJIJIJJHHHHFFFFEEEEEEDDDDDDDDCCDDEDDDDEDDEDDDDCDDCDDDDD
@17M
AGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACT
+
CCCFFFFFHHHHHIJJJJJJJJJJJJJIJJJJJJJJIJJJIJIJJJJJJJJJJJJJIJJJJIJHHHHEHFFFFEEEEEDDDDDDDDDDDDDDDDDDDDD
@17N
GCGTCACAGAAGAGACCCTCCCAGAGGCACGGATCCAAGTACCTGGCCACAGCAAGTACCATGGACCATGCCAGGCATGGCTTCCTCCCAAGGCACAG
+
@@?DDDB:?+ACFHED7ADCEFG>?CF7BB6?))89?D8DEGG*=CFBCDA9C;DE)=AHA:CDEE)((6;>(5=A?(;A9929>::5<?>8?<<((3
@17O
TGGAAATGGGTGAGGTTGTTGAAAAGGATACAACAGAACTCATGGAAAAACTTGAGGTAACCAAGCGAGAGAAATTAGAGCTGTCACAGAGACTGTCTGAT
+
+??DDDDDFFC?:EFABF@GGHFCCFEFIIFEGEAFFGFIIIIFIIIIID6FFIEFI=CFEFE@D;AEFDDCCCCCCBBAABBABBBBABBBBBBBBAABD
@17P
TCCTACAAACCGAAATGAGCAAGTCCCGTAACATGTGACAGGATGGCTAATTTCTTGACAATTCACCGTCTTTTAATCCATAAAGAAATGCAAACAGGAA
+
+1=+2A37+2+0<0)2+2<+2+++:=*11)0):**00*09*)0/*<7))9)))./7))).7...)).(.5.5.(((..(.(((--;,55(5((5(((99(
@17Q
CGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCC
+
CCCFFFFFHGFHHJJJHIIJJJJJJJJJJJJJJJJIJJJJIJJIJJJJJJIJIJJJHHHFFFFDDEEEEDDCDDDDDDDDDDDDDDDDDDDDDDDDDDBDD
@17R
CCTTTATTCCAGCTGTCTAACTGACAAGACCTTTCTCTCTTTCTTTCTGCCTCATGCTCTCTCCAACAGGCTTGCAGCCAATTTACTGGAGCAGGGATGAC
+
CCCFFFFFHHHHHJJGIJJJJJJJJJJJIJJJJJJJJJJIJJHIJJJJIJJJJIJJIIJJIIJIJJIJJJJJJJJHHHHHFFFFFFDEDCEDDDDDBDDDD
@17S
CTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGCCAGCTATACCCAGGCTCAGACCACTGC
+
=:;DBD?DHHFBAF>B;EAFDDHI;<8CH3:?9?>@??GGGFCGEHG4D?8C=88==C=CGEEII=;=7;;7).7;A:@>@CCCCB?B9@A(5:<32>@@
@17T
TTCAAAAGCAGATTCAGGTGTTCATTTATGTGTTATTGATGACTCCAATGAGCATATGCTTACTGTATGGGACTGGCGGGGGAAAGCAAAAGGAGCAGAA
+
;;?1?:AB:D?<CAA,<3C?FF@@D?F@?@F<F><?CE?B?F9??FF3?B9<D9B?B<<8?D?8===883()=;@C9'5'05&0<?39?>@A?28(8<3?
@17U
AGCTCTTCTGGATGACCCTTCAAATTCTCATTTTATTGCCTGGACTGGTCGAGGCATGGAATTTAAACTGATTGAGCCTGAAGAGGTTAGTTTAATAGATT
+
?@@FFDDFFHHBFHEDHJGIJJJJGGECFIEFDAGHGFGGCCGEICHIFFHFHHIJIIIGHEHGGIJ?EHAEC@DDDFECDCE6?A;?>=ACDDDA@CCDD
@17V
CTCATTTTGTTAACTATTCAGAGACCTTCTCCCTTTATTCCAGCTGTCTAACTGACAAGACCTTTCTCTCTTTCTTTCTGCCTCATGCTCTCTCCAACAGG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJIJJIJJJJJJJJJJJJJJJJJJIJJJIJIHHHHHHFFFFFFEEEEEDDDD
@17W
GTTTTGGCTGTGGAGTTTCACCCAACAGATGCAAATACCATAATTACATGCGGTAAATCTCATATTTTCTTCTGGACCTGGAGCGGCAATTCACTAACA
+
=1:AA>AAB<AACBC7@C<43A3AB15)@:**:?A?AABBB3?AB49449*(<-:;>A4A;)=.==;ABAA3..));7;)6;;;;=628+++4:3;98;
@17X
GGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATG
+
BBBDFFFFFHHHHJEFHIGEHIJJIIIHIIGIJJJJJIIIJGIJIHIIJGGCG@GFHFFEEDD@DBDDCDDDEDDACCDDDDDDBDDDBBBDDDDDDDDDD
@17Y
GTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGC
+
@@@DDDDDF3AFHBH@EHGIGEGGGEGHGGGHIIIIIGIIDDHIIIGDGGGIIEGEEECCEGFEEEEDEE@CCCCCCCCCEECDCCCCCBBBCCCCC8<A<
@17Z
CATTGCCCAGGCTCTGCAGCCACATCCGACCGAGTCGTCCATGTACAAGTACCCTTCTGACATCTCCTACATGCCTTCCTACCATGCCCACCAGCAGAAGG
+
;@<=BD?D8??F?F@4EEDHIGI>GIE@CGFE<FFFA;C?A@F@@FGEE@CGGC>;?CDC>CCD:ACCAC@3>CCCC5:@>AB:@:>@C>?B8289?C>9@
@180
CTTTGCTTTTTTTATTCTCTTCCACTTCCTCTTTCCTTTTGTGCTTTTCTTTTTTCTTTTCCTTCTTGTCTTTCTCCTTTTTCTTTGGTTTGTTCTGCTGG
+
@@@FFFFFHHHHHJJJHIHIJJJJJIIIIJJJIJIJJIGJIFGHIIJJIJJJJJJGIJJJJJJJIHHHHHHFFFFFEEDDEECDDDCDABDBDDCECCDCD
@181
AAGTGATGTATGGTCTTTTGGTGTACTGCTGTGGGAGATCGGGACCCTAGGGGGAAAGCCCTATGCTGGGATTCGTCGTGAGCGGGTCTTGAACCGTCTG
+
7(;(@6)=.86<?6..).);3(<()2)8@9<6@>@19=)):(7((0().:>?<?/'((..97(0(-(7:<5(,,(,(')028/55&&&((((+((&+&(+
@182
CAAGAAAACAGGGAATTTTTGGGAAATATGAAAAGCCAAAATTTGTGCAGTGTTTAGCATTCTTGGGGAATGGAGATGTTCTTACTGGAGACTCAGGTGG
+
@<@ADFFFFBFHHIHIFHIBFGEGIE<9CGHIDGG3?FDF?BG@@8?DF?*=CGGIIIIIGH<FGIDE5A;BDDEC;A;@@AC5;;>>?2?<>CCCC5:?
@183
CATTTATATGAGGCAAGAAGGCTTCCTGGCTCATCCCAGCAGAACAGAAGGCTGTATGTTTGAAAAGGGCCCCAGGCAGTTTTATGATGACACCTGTGTTG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJGHGIIJJJIJJJJJHHHFFFDDDDDDDEDDDDDEDEDDDDDDDDDDB
@184
CAAAGCCTTGGCCCGGAGGCACCTATCCCAGAGTCCTGACACAGAAGCTCTTTCCTGTTTTCTTATCCCAGTGCTTCGTTCCCTGGCCCGGCTGAAGCCC
+
:?<1+A:BF>CFAFB::@F?G>;;D<FFEBEFB9BFEA@;DEDEBDE@F@@EFECCA7=?EEEBD:@;?>;@BCAA>?@BB?@ABB<?90059@<@((28
@185
CTTAGAGCAACTCAACCAAGTGAAAATGATAAACTTCAGAAAGAACTCAATGTACTTAAATCAGAACAGGACTTGATTAGAGACCAAGGATTTCGTGGTG
+
C@CFFFFFGGHDFIJJJIJJIJIJJIIIJIJJJJJJJJJIJIIJJIJJJIJJIIJIIJJIIGIGGIGJIJGHIJJJHGHHHHECEDDEC@CDDDDBBD9@
@186
GGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGG
+
@CCFFFFFHHHGHJJJJJJIJJJJJJIJJIJJJJJJJJJIJJJJJJJIJJJJHHHHHHHFFFFFDDDDDDDDDDDBDDCDDDDDDDDEDDDDDDDDDDDDD
@187
GAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTC
+
C@CFFDFFHHGFHIGDGIJJJJIBEHGGDAGEHGGIGEHIIIGHGIJJJJGIEHEHHFDFFFCBDDDBDDDBDDDDDDCCDDDDDDDDDDDDBBDDDDDDD
@188
ACTGACCTTTCACAAAGAAAAAATATTACCATAGAAAAAAACTGAGCTTGTCATTTTTTCCCTTGTAGCTTTAAGGAAAGAAATAAGTGACTTACATTAA
+
;;3>5@2<4):?>9)2):<==183@)2):)):)26)))6(7-)<).).<).))).<).:<=;8;).9(66(64((-5(((,(5;=5(,((36+((52(((
@189
GCGGCAATTCACTAACAAGAAAACCGGGAATTTTTTGGGAAATATGAAAAGCCAAAAATTGCGCAGAGTTGAGCATTCTTGGGGAATGGAGATGTTCTTAC
+
=+12?=AA++??<<27++3?++<C+1?A4:><7*9<4=AA>;.).=7==>AAA@@>;((.;(3;=='9(5(,53933((((+2&8&9??;<;3:(3(+3:8
@18A
CTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTC
+
??@DFFBDFFFFHGFEGAFE@BHDHIIGGHIEGGG?G:?CFFFHEAFFD?FGEHEGGBAGHEGGCD>CDAEAACDBBEFA>>@AEB@BBCCCBCC9:AACE
@18B
CTCACAGTAAAAATAGGTGATTTTGGTCTAGCTACAGTGAAATCTCGATGGAGTGGGTCCCATCAGTTTGAACAGTTGTCTGGATCCATTTTGTGGATGGC
+
???14B?D8FF<D?AEE<3AB<E@DG;++ACF@FCGFGEFFF@?D*:DBD<FE?B7B;FFE:C=@F)=CCEE>;?C>AECDBD:?BCAC@A;A5=@>ABB<
@18C
CTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCC
+
@@<DDDDDBBDFHBGHAAHG=8?D?C?@DHH@;DBFG@G@?8@45;@=3=>?.==A>B?B?@>>6(>CC@;;;;5@:AC::>::355<@8880<18A?:88
@18D
CTCCTTGAATCGGGCTGGTTTCCAAACAGAGGATTTTAGTCTATATGCTTGTGCTTCTCCAAAAACACCCATCCAGGCAGGGGGATATGGTGCGTTTCCTG
+
CCCFFFFFHHHHHIIJIJFHIHIJJJJJJJJJGIJIJGJGIJJJJJJJIJJGIJIJJJGIJJJJJJGHHFFFFFEEEDDDDDDD<<ACDD>ACD?@DDDDD
@18E
CACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCA
+
CCCFFFFDFHHHHJJIJJJJIGIJHIIGIJJGIIGEHIJJJJGIGIHGBHIJIGGIJJJJHHHHHHFFFCFDCEEACDCDDDDDDDDDDDCCCEDDCCDD
@18F
AGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGG
+
CCCFFFFFHHHHHJIJJHJJJJJJJJIIJJJJJJIJJJJJJHIJJJJJJJJJJJJJJJJJJIJIGIIHGHHFFDDDDDDDDDDDDDDDDDDDDDDDDEDDD
@18G
CCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTAT
+
@7@D:B4BD333DFGDFA3C@DA@FCGFD@BFDFGIEFDBFEFF@BF8AECEF=BDDBBAB6>@B:AAB@B?@?B@@B?8<??A:A:@?BBB?BBB?BBA4
@18H
GGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACAC
+
?@@FDFDDHFHFFIGHEIGIDHICHHEC<?FHGGGEEHGBGBGGICHEDGGDHGIEGIHHGHGEGDGIHHGHFFFFFCCCEEC?CC?CCCCEECCCCCCC
@18I
CAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATAT
+
CCCFFFFFHHHHHJJJIGHIJIGIJEHIHGIIJJJJJJIIGCEHGIJIIJJGICEHGIJJJJJJHHGGFFFFFFEEEECCCDDDDD@CDDDDCDDCBCC
@18J
TCAGCGTCCACTGCTGAAGACAGACATGGAACGTCACATCAACGAGGAGGACACAGTGCCTCTTTCTCACTTTGATGAGAGCATGGCCTACATGCCGGA
+
@CCFFFFFHHHHHJJJGJJIJJJJJJJIJJJJJJJIJJJJJJJJIIIIIIIIGHJJEHGHGHFFFFFFEEEEEEEDDEDDDDDDDDDDDDDDDDDDDDD
@18K
CCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGT
+
CCCFFFFDFHHHHJJJJJJJJJIIJJJJJJJIIIJIIJGIIJGHJJJJJJJGIJJJJJJIIJHHHHHHEFFFFFDDDDDDBDBABCBDDDDDDEDDCDDDC
@18L
TCAACTTGGGGTCCCCAGGGAGAAACCCCTAGCTCTGGGAGTAGTTCGACCCTCACAGCCTCGTAAAAGGCGGTGTGACAGTTTTGTCACGGGCAGAAGG
+
@@<?DDADBA?)@EGGFGGEBF@FHIIEBBFAGHIGGCB9BGGG888;CHHIIICEHFCD>?<6=A?C>BABB05)<>@CC@ACC?8AAC@@BBB5<?C?
@18M
ATTTATTAGAAGCTTATCCATCCCTATTACTTTTTTAAATGGCATTAGTTCTGTGTGCTATTGGTGTTTATTTGCATCCACCTGTCCAGTTGCTCTGCTGT
+
<BBFFFFFHHHFHIJJJJIJJIIJIEIIJIJJJJJJIGGBGIIJJJEHHHGGIFHFHGIIIIJJ8@FHIIJJJJIHHHEEHDFFFECDECEDDCDDDDDDC
@18N
ACTGCATCAGAACCATGAAGAAGATAACTGTGTCCAGAGGACCCCCAGGCCATCCGTGGATAATGTGCACCATAACCCTCCCACCATTGAACTGTTGCACC
+
@@@FFFFDFBFHABDBGIJIIJJEDHHHBBHGGHJEFHJGIIJIJDIGFHHEHIGB5CHGEHH>A7AEEDFFFFCEE?>ABBCBDDDDCA@ACCCDDDDDC
@18O
TGATGATGGAGGAATCTGTTCAACATGTTGTCATGACAGCCATTCAAGAGCTGATGAGTAAAGAATCTCCTGTCTCTGCTGGAAATGATGCCTATGTTGAC
+
@C@FFFFFHHHHGJJJJJIIIIIIJIJHIJHIIGHIGIIJJJJJIIIJHIIJIIJJGGBGGGAHIJGJJIIIEHIGGIGEHHHFDCFDFEEEEDEEDEDCC
@18P
AGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCT
+
@?=DDDDBFDDHHBHIEGGGGIGIGGCHI@GHGE@BGEEHHGIIIBGIEAEDG;EGGHEF=BEBCC@C@CCCDC@DCCCCCCCBBB@?<8:@CA>CDCCD
@18Q
CCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIIJJJJJJJJJJJJJHHHHHFFFDDDEEDDDDDEDDDDDEDDDDDDDDD
@18R
CAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGG
+
;?@DDDDDHHFFHIII@GEHHGDGIGIIFGGHIIIGIIIIIIIII;DGIIIIIIGEIIIIIII=>CCDBEEEEEEECCBBBBBBBBBBBB@BACCC@ACBB
@18S
CTCTTCACAACCTCTCCAAATACACAGACAAACTCCAGAAAGCAAGAATGCTACTCCCACCAAAAGCATAAAACGACCATCACCAGCTGAAAAGTCACAT
+
BBCFFFFFHHHHGJJJJJJIJJIJIJJGIIIJIJIJJJJJJJIJJJIJJJIFIGIJIJIJJJJJJJJHHHHHHFFFDDDDDDDDDDDCDDDDDDDDEDDD
@18T
CGACGTTGGGGCATTCAGAAAAACAGGCCAGCTATGAACTATGATAAACTTAGCCGTTCACTCCGCTATTACTATGAGAAAGGAATTATGCAAAAGGAGGC
+
>=;+2A;+<0)0<C+22?>AB;5?;75<53:5*:==A70=*0/9779>3).=AA;'--).)7))(94,=>@B>5-;-(;=;:5299;>95,9;888;(+02
@18U
CTATGACCCTGGAGGAGGGACTGCCATTGGCTGTGCAGGAGTGGGAGCACACCAGCAACTTTGACCGGATGATCTTTTATGAGATGGCAGAAAGGTTCA
+
@@@DFDFDFHHHFHIJI6EFGGHJIJGGEEFHGHJEHHGAG;BFHCHGFHIGIIFGEHFHFFFFDDBDBDBDDDDDDDDDDDCDDDC?C??CDAB4>A@
@18V
GCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGG
+
?@<DDDDFDHHGFIGGBGHCHHIGGIJIGD?DBFICHGDHGHGFDHGGGHIGGHIGGGHHEEAC@BC@BCCCDB;@?ACCCBB@<@DD<ABDCCDCCCCA@
@18W
ACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGG
+
CCCDFADDFHGHHIJGIJEGGHIJIIIGHIFGHIIJJJEGGCHHGIGJIIIIJFGHJCEGGIEGDHGGFHGHCFFD;A;C@CDCCDDCDDDCCCCDBDDD
@18X
TTATTAGAAGATTATCAGAAAAAGAAAGAAGACTTCACAATGCAAATTAGTTTCTTGCAAGAGAAAATTAAAGTATATGAAATGGAACAAGATAAAAAAGT
+
CCCFFFFFHHHHHJIJJJJJJIJJJJJJJJJJJJJJJJJJJIJJJJJJIIHIIJJJJIIJJJJJIJJIJIJJJ;EGGGHHHHEHFFFBEEEEDEDDDDDD:
@18Y
GATGAAATCACTGTGCTAAAGGCGGCTTTGGCTGATGTTTTGAGGCGTCTTGCAATCTCTGAAGATCATGTGGCCTCAGTGAAAAAATCAGTCTCAAGTA
+
?=??DBDB?DBFFF<4EEAHFF=FF<?0DF3D??;DAFFF@BCC8@4-=/;B@BC>;@ADBBBA@A>>A>(::??@BBABB<ABA<0<>@@>:>@AA>A>
@18Z
CAACTCATACACCGAAACCTGACCGGGCCTTCCCAGCTCACCTCCCTCCATCGCAGTCCATACCAGATAGCAGCTACCCCATGGACCACAGATTTCGCCGC
+
@@@DFFDFD?FHDHIGIIBHHEGEIIJF@BB@FFHGJJFGIADGCGGIEHHEEFFFACCCECDCCCBD@C@@CACDACABDCCCDACB??BDCDC>CBDD@
@190
CCCACACCTGGGAAAGGACCTAAAGGTGTATATCAAATCAGCAAACAAATCAAAGCTCATGATGGCAGTGTGTTCACACTTTGTCAGATGAGAAATGGGAT
+
8?@DDDDDHHHHFIIIIB@EFHGIID?FGHHDFHIIIGABDHIIGEHGFEDHIIIIBAHII@GGIIIIDE7A?EABBDDECCCCCECCCCCCCCCCCCBCC
@191
CTTTTTTAAATGGCATTAGTTCTGTGTGCTATTGGTGTTTATTTGCATCCACCTGTCCAGTTGCTCTGCTGTCTTGTGTTTTTGCAGCCTCTACAACCCC
+
@@@DDDDDDBHDDE;EEGFHFHI@HIIIIADFHIE?CFEGHGHEGICGGIEEGE?BHEHIIIIIIIBGGGGHIHFF?ABCEEE<A@>AA?CCCCCCCBBB
@192
CCAGAGTAGGGTTTGGTGTACAAACTGCTCCCTGGACTCCTCTTGGAGGCTGCTTCTGGGCTTCGAGAAGCCCCCAGTGGGGCGGCTCAAACAAGGGCTGG
+
CCCFFFFFHHHHHJJJFHIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJGIJIIJJJJJJJHHGHFFFFDDDDDCCDDDDDDDBDDDDDDDDDDDDDD
@193
CTATTCTTCAGTATGCACAGACCTCTGATGGACAGCAGATACTTGTGCCCAGCAATCAGGTGGTCGTACAAACTGCATCAGGAGATATGCAAACATATC
+
CCCFFFFFHHHHHJIJJJJJJJJJJJJJJJJJJJJIJJJJJJJJIIJJJJIJJJJJIJJIBGHHIJIJJHHHHHHFFFFFEEEDDDDEDDEDDDDDDED
@194
ATGACTGTGGCCTCCAACCAAGGGTCAGCGAGGACACCTGCCCACTGAATGTTCATTCTTATGACCCCCAAGGAGAAGGCAGGGTGGATCCTGACCGGGCC
+
1=1?17+<<;+2ACC9CC)A7?A<CBBBB6):?6=;AA*7(5=>5=8A>B>)..=7AB>.7))=.;((,3;55;((,9=9,8;999;(8:338((+&0&00
@195
CACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATG
+
@@@DDDDA?<B?DG@EHH<E,AAFH;=9A?EHIFGBHE;FCDEGCFGD@F@=@GAEGHFHEBCCB??=@=9:>>>?:>@5;5+(+++8?<@@@B0<@C@34
@196
AACTGTTGCACCGCTCCAGGTCACCTATCACGACAAATCACCGGCCTTCTCCTGACCCCGAGCAGCGGCCCCTCCGGTCCCCCCTGGACAACATGATCCGC
+
@@CFFFFFHHHHFIGJJIJJGHBGIJJJJJJJIGGFGHIIIJJBGIGIJIJHHHGHFFFDDDBDDDBDDDDDDDDDDBBDDDDDDDDABDDDDDCDDDD?B
@197
ACCTGGGCCATACAGACTGTGTGAAATGCCTTGCTATACATCCTGACAAAATTAGGATTGCAACTGGACAGATAGCTGGCGTGGATAAAGATGGAAGGCCT
+
CCCFFFFFHHHHHJJJJJJJIHHIJJJFIJJJJJJJJJJJJJJJJJJJJJJJJJIJHJIJJIJJIIJIJJJJIHHHHHHFFADDDDEDDDDDDDDDDDDDD
@198
CGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCA
+
@BBFFDFFHHHHHJJJJJJJJJJJJJJJIJJJJJJJJJJJIJJJJJJIJJJJJJJHHHHHFDDDDDDDDDDDDDDDDDEDDDDDDDDDDDDDDDDDDDD
@199
CAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGC
+
BB@FDEFFHHHHHJJIJJJIJJJJI<HHIJIGHIJJJCHIJIIJJIJJJJIGIJJIJJIJJJJJGIHFHHHHFFFFFFDDDDDDDDDDEEDCCDEDDDD
@19A
CACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCC
+
CCCFFFFFHHHHHJIJJJIJJJJJJJJIGIJJJJJJJJJIJIJJJIIIIIJJJIIJJJIIJJIGIJIJHHHHHHFFFFFEEEEEDDDDDDDDDDDDDDDD
@19B
CAGTAAGGTACGGAGTAACTGTCCAAAAGCCATGAAGAGATTAATGGCAGAGTGCCTCAAAAAGAAAAGAGATGAGAGACCACTCTTTCCCCAAATTCTCG
+
@@CDDFFF?FDFHJJEFHHEHIIJIJJJIIJIIGJJJIIIJIIEIIEIECGH?=FGHJJGGGIIIGIHHEHFFFFFFEDEDDDDDCDDCDDDDDDDDCDC<
@19C
CGACGATGCCAAGGGAAGGACGTCCTATGTACCAACGCCAGATGTCTGAGCCAAACATCCCCTTCCCACCACAAGGCTTTAAGTAGGAGTACCACGACCC
+
CCCFFFFFHHHHHGGGHIJJJJIIJJJJIIIJJJJJJIJJJIJJHJJJIGIJJJHHHHFFFFFEEEECDDDDDDDDDDDDDDDCDDDCC?CDDDDDDDDD
@19D
CGGAGGAAGAGGACAAGTGCAAGCCTATGTCCTATGAGGAGAAGCGGCAGCTCAGCTTGGACATCAACAAGCTCCCCGGCGAGAAGCTGGGCCGCGTGGTG
+
@CCFFFFFHGHHHJJJJJIJJJIJJIJJJIJJJJJJJJJFIJIJIIIJIIIEGHFGHGFFFFFEEEEEEDDDCCDDDDDDBBBDBDDCCDDBDDBD9@D?B
@19E
TTACATCACAAGACGACATGCACTCCTGAGATGTGCTTACATTAGGCATAAAAAGGGATGCAATTCCCGGTGGGATAAACCAAACGACGTTCACCGCGAA
+
-73<=>4=>>@?><((-(2)2;9))..1).)1=;)))..).>9;)<=).700:1'(-6993:;))6:8'5,,3'((9(-(,5,5('')&&+(+66(&&))
@19F
CAGGAAGAGAAAAGTAGTTTGTTGGCAGAGAATCAGGTATTAATGGAAAGACTCAATCAATCTGATTCTATAGAAGACCCTAACAGTCCAGCAGGAAGA
+
B@@FFFFDFHHGFHCFHCJJGGGHHIJJJJEGIGGHG?FGIGGIIJIJHHHIJJJJJGGIHHEHIJJIGJJJJJJJHFFFFEFFFDCEECDCDDD@BD@
@19G
CCACATGCCAAGGCAATCTCCTTATCATGGGGACTGAGGATGCCTCCTCCTTGCCTGAAGCCAGTCAAGAGGCAGGGAGCAGAGGCAATTCCTTTTCTCCT
+
CC@FDFFDFFDFHGIJJJJJJIIJIEFGHGIIGEIIJIJIJCHGIGIIEEDFGGGIIIJGGGIJECCECAEEDBBCBDDDDCC?@BB?CDCCCCDD@CDDD
@19H
CAGCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCT
+
@@@DFFFF?HHFHIGGGIJJIGEHIJGAEIIGIGIEGDHIEBDEECHIIIIGCGHGEIIAFEHIEDHHE=?@DFD>?CC@CCCDCD@C:?2?B?DBD@BB
@19I
CAGTAAGGTACGGAGTAACTGTCCAAAAGCCATGAAGAGATTAATGGCAGAGTGCCTCAAAAAGAAAAGAGATGAGAGACCACTCTTTCCCCAAATTCTCG
+
@@@DDFFFDFHFHIGACGEHGIJIJJJJJJJJJJEGGDGFHEIIHHGAGHEF9BCFGHGIGIEGCEHFHAEBDDCE@>A@ACBCDCCCCCCCDDDDDDDDD
@19J
CCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHIJJJJJJJJJJJJJJJIJJJIHHHFFFFFEEDEDDDDDDDDCDDDDDDDDDDDD
@19K
GGGAAAGCGAGAGGGAGACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGG
+
CCCFFFFFHHHDHJJJJJJJJJJJIJJJJJJJJIJIIJIJJHHHHFFFDDEEEDDDDDDDDDDDDDDDDDDDEDDDDDDDDDDDDDDDDDDDDDDDDDDDD
@19L
CCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTAT
+
@@@DDD;DFDDFD<FFFIIEFEEABFCFEFG@D@GFIEFECFEE;AAABEBECEDDDDDA@BACB@A@A3=?<?@?BBBBBBB:@BDBBBBBBB@BB?BBA
@19M
CAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCC
+
?@@DDAADFDHHHGAEHGEHFIHIIAFFHIEIEIGIHIIGIIHD>GHHIIEHFF@FGHCGGHGGIEGIFHDEHFDFFECEDEDDDDDCDCCDDDDDDDBA@
@19N
CTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTAGGGGCAACCGAGC
+
?18:D3++=A3ADE<4A+:+33A+28<A@E<9:<4?@*?1:)0?8BD(07@3A9ACEI;C7@).@77.7=);3)7.7(;(;@((5(--(,(3,'+8<?00;
@19O
AGCATGGCCTACATGCCGGAAGGGGGCTGCTGCAACCCCCACCCCTACAACGAAGGCTACGTGTATTAACACAAGTGACAGTCAAGCAGGGCGTTTTTGCG
+
@@CFDDFDHDFFHEAFHIIJIJJGFIIIJJIJGJDGGIJJIHHHFDFDECCBBDD@BDCDB9A>ACDDEDDDDBD+:@CCA>ACAAC???B?@09@BBBC@
@19P
AAGGAGATCTCTGAACTTCGGCAACAGAATGATGAACTGACCACTTTGGCAGATGAAGCTCAGTCTCTGAAAGATGAGATCGACGTGCTGAGAC
+
?;=A:2BDFFF<AFDGIEC<<FGI;8:EGC9*11:?:0:BGI<8D?309DB;1=BF@7CFIC;=77C@7?==77)7?7.7>;;>B3(,(5:?5@
@19Q
CAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATAT
+
@B@FFFFFF?HHHIJGGEHGCHIJIHHJIIGJIJGGFDHGDGGIGIGIGGHIIDGIIIIGGIIJGEHFFFFCDFCCCEEDDDBDDD@CDACDCCDDDE>
@19R
CAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATG
+
CCCFFFFFHHH<DHHIGHIIIIBB@ECGGIGIJJGIIAGIGIIGIIEIGIJFGHGGIACFHHEE@CHFHHGFFC>??CBDCACCDCC@BDDDB>ACCCDDD
@19S
CAGAAGTCATCAGAATGCAAGATAAAAATCCATACAGCTTTCAGTCAGATGTATATGCATTTGGAATTGTTCTGTATGAATTGATGACTGGACAGTTACCT
+
CC@FFFFFHGFHHJJIJJIIIGGIIGIGIGIJIGHIJJIJIGIJJGIGGIJIHGGIJIIHJJJJHJJJJIJHGGIGHIHGIIGEHHFEEHHFFFDEEECAC
@19T
CACGACATGTGAATATCCTACTCTTCATGGGCTATTCCACAAAGCCACAACTGGCTATTGTTACCCAGTGGTGTGAGGGCTCCAGCTTGTATCACCATCTC
+
@@@DDDDDHABFHGFE?CBEDGDEHDH?@DBGE;GBCAFHEHGIIIGIGEHG>FGHHIHECEHGGHCG@DC7?=?DDD=A;?BCCACC??@@CD:AA@CCC
@19U
CACCGCAGTGCATCAGAACCCTCCTTGAATCGGGCTGGTTTCCAAACAGAGGATTTTAGTCTATATGCTTGTGCTTCTCCAAAAACACCCATCCAGGCAGG
+
CCCFFDFFFFHFHIIJJHHJIGIGIIIGIJGIIGGAHIBFGHIGIJJIGGHGIIJJGEEACHFCECADEFCED@CCACCCCCDDDDDDDDDDCBCCC?A@@
@19V
ATTCACTATAAACAGCAGATAGATGGTTTACAGAATGAAATGAGTCAAAAGATAGAAACCATGCAGTTTGAAAAGG
+
?@@FD>DBBB>FFHIBHE@FGEHGECACECHIIE@C<FGG@DB?DF@BGICFG@D<FG;BCBFEIIFED@=CEE<@
@19W
CTTCCGGGGGCCTCACTGCTCCTAGAGCCCTCTTCGCTGACTGCCAATATGAAGGAGGTACCTCTGTTCAGGCTACGTCACTTCCCTTGTGGGAATGTCA
+
@@@FFFFFFHHHHJJJIJJIIGIIIJJIJJJJJJJGIGHGFFFFFEEEEEEEEDCDDD8@CDDDDDDDDDDCDDDDDDDDDCDDDDDDDCCDDBDDD@DE
@19X
GTTTGAAATGAATGGCAAAGCTCTCCTGCTGCTGACCAAAGAGGACTTTCGCTATCGATCTCCTCATTCAGGTGATGTGCTCTATGAACTCCTTCAGCAT
+
CCCFDFFFHHHFFIJJJIJGHIEHIGIGIJJIJIJIJJJJJJJIIIJJJEFHJIJJIJJJIEGGGGHHEEHF;BDDDDFCCEEEEEDEDDDDDDDDDDDD
@19Y
GTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTAC
+
CCCFFFFFHHHHHJIGIIGIIIHGIJJJJJJJJJDHIJJIIJIJJJJJJJJJJI@FHIHGIIGHIIHGHHHFEFFEEECEDDDDDDDDDDDDDDDDDDCDC
@19Z
TTGGACTTGGCACTTTTGAGCGTGGAGTAGGATGCCTGGATTTTTCAAAAGCAGATTCAGGTGTTCATTTATGTGTTATTGATGACTCCAATGAGCATATG
+
@@CFFFFFHGHHHIIIJIIJJJEHI?FFGIIGGGEHIJIJJIJJJEIJJIJJJJGCHIEIJFCEHHGFHGFHFFFFFFFFFAEEDEEEDDDDDCDDDDDDE
@1A0
GCCTCTATTGAGCTGCTGGCCCGCTCATTGCCAAAAATTCACCGCAGTGCATCAGAACCCTCCTTGAATCGGGCTGGTTTCCAAACAGAGGATTTTAGTCT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJIJIJJJJJJJIHIIJJJJIIJHHHHFFFFEEEEEDDDDDDACDDDEDDDDDDDDBDDDDEDACD
@1A1
CCACAAAGCCACAACTGGCTATTGTTACCCAGTGGTGTGAGGGCTCCAGCTTGTATCACCATCTCCATATCATTGAGACCAAATTTGAGATGATCAAACTT
+
8;;???;DFBAFF;<BGAB;?EEB<9<A??CFCGF*:?DE@;B@DEF93?=8=FFEF:C@;DC@CEDE>?CECABDDBBCCC?ABBAB??@>BAAAABBBB
@1A2
CTGAATATAAAATTGCAAGATACTAACTCTCAAAAGGAAAAACTCAAGGAAGAACTAGGACTAATTTTAGAAGAAAAGTGTGCTCTACAGAGACAGCTTG
+
@@@DDDDDFHHFDHIIJIHBHBEGGHCFEHEGEIGG?E>G?DFFEEHIEII9FE>BCFF8BFDAHHG@HGIEGGGEEE=?)7;?CDDCEECCDCCCDCDD
@1A3
AGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAAC
+
CCCFBDFFGHHGHGBGIIIGGHGIGD@HIFHFDHGIIEGGHIIIJGEAHGFHHEFFFFDEC>CACCCDBCBD@BBD<ACD@CAB??BDBB?ACDCDCDDAA
@1A4
GAAAAATTCGATGGAGACATCAAACAAGAGCCAGGAATGTATCGGGAAGGACCCACATACCAACGGCGAGGATCACTTCAGCTCTGGCAGTTTTTGGTAGC
+
CCCFDFFFHHHHHFIJJJJJIEHJIJJIIIJJJIJJJJJHIIJJJJJIIJJIIJIIJIIHEEHFFFDDDDD@CCDDDDDADDDCCCDCCDCCEDD@B?CCC
@1A5
ATCGTACTGAACATCGTGGAGGCCTCGAGGGAGAGTGCCAGCACCATTATGGAGAATGAGATGATGAAGATTTTGTCAGAACTAGCTAATGGTGACCAC
+
(((2-(..2)9>1.)((2((.:((..(((5(5==(0)6.).<>3>(</8)3>8;.().)).:)))3)..63(:=1395;((,(:,52(:((,(((5(36
@1A6
GTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGC
+
??@DBBD<DFDDD@EBG@GG<CAEHGHIGDHIGGFHGHGGIGIIIFGIGIGDHIIGGGGEGIIEFHFDDEEECCCCC@;@CCCACACECBCCCCCCCCC?A
@1A7
AGTTACAAGCCTTCAAAAATGAAGTAGGAGTACTCAGGAAAACACGACATGTGAATATCCTACTCTTCATGGGCTATTCCACAAAGCCACAACTGGCTATT
+
<@@DDFFFHHHHHJIJGJHHIGGIIIIIHIAFHHGGJIIICHCFGGHJFHIFGHIGIEIJEGFGIGIGIGHHGHFFEDFFFEEDCCDDDCDBBDDD?ACDC
@1A8
CAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGC
+
@?@DAFDD?BFDBGEGBEEDDCHEEGE:CC?FCEGGBHBFHIIIIII@FEH@CBGIIGIG>@EHDG>?C@?BBDDDDCBBBCBDDCDC@3:>CCDDDDDC>
@1A9
CCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACC
+
1+1<+?+A=CB8++<=?+?+<=3AACA<A777**?A?ABAB<;0:=??A9AA;<(===5=<AAA>))6=>73;?9);>@@@:=35=;>;5(9>919952
@1AA
AAAGCCTTGGCCCGGAGGCACCTATCCCAGAGTCCTGACACAGAAGCTCTTTCCTGTTTTCTTATCCCAGTGCTTCGTTCCCTGGCCCGGCTGAAGCCCAC
+
CCCFFFFFHHHHHJJIIJJJJJJJJJIJJIIJGJJJJJIJJFGIJJIJJJJJIJJJIHHHHHHHFFFFFEEEEEEEDDDDDDDDDDDDDDBDDDDDCDDDD
@1AB
TGTGAATATCCTACTCTTCATGGGCTATTCCACAAAGCCACAACTGGCTATTGTTACCCAGTGGTGTGAGGGCTCCAGCTTGTATCACCATCTCCATATC
+
?<1ADDDBDDEDDIIIEEDIIE3CEFII@FEEBEEEEEDDDI@DDCEDDDDEIDECDEICDCEI=A=5==>DD2A@A>AAA@@ADAAA?AAA3:>>>>A>
@1AC
ACTGACAAGACCTTTCTCTCTTTCTTTCTGCCTCATGCTCTCTCCAACAGGCTTGCAGCCAATTTACTGGAGCAGGGATGACGTAGCCCAGTGGCTCAAGT
+
CCCFFFFFHHGHHJJJJIJJJJJJJJJJJJJJJJJJIIJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJHIGHHHFFFDEEDDDDDDDDDCDDDDDDDDC
@1AD
CGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGG
+
@@BFFFFFHGHHHJJJJIJIJIHJJJIIIJJJIJJJJJIJJJJIJJIIJJJJJIJJJJJIJJIHGHHHFFFFDEEEEEEDDD>CDDDDDDCCDDDDDDDDD
@1AE
CCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGAT
+
CCCFFFFFHHHHHJIIJIJGGJJJGIJIJJJJJJIIJJIIGGHEHJJJJIJJJIIJJJHIIIIJJJJIIHGHEFFFFCECEDDDDDDDDDDCDDDDBBDD>
@1AF
AATAATCACTGCCCAGCGTCCTCCGAGTCCCACCCGAAGCCATCCAGCCCCCGGCAGGAGAGCACACGCGTGATCCAGCTGATGCCCAGCCCCATCATGC
+
CCCFFFDFGHHHHIJIGGHHIIBGHIJDGIBHJJIGIJIJIJGIIJJGIIJHFDDDDDDDDDDDDDDDDD@BBDEDDDDDDDCCDDDDDDDDDDDDDDDC
@1AG
GTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGC
+
CCCFFFFFHGHHHJJJHJIJJJIJJJGJJJJJJJJJJIJIGJJJJIJJJJIJIJJIJIIJJJJHHHHHFFFFFFEECCEECDDDCCCCDDDDDDDDDDB
@1AH
CCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATT
+
;;=DDD??4??DDDEE+2<C3AFA3AEEFECBF@D3:?D@DD<D@@BDA@>B?DBCCBA;=)=@A.77==3A)=?;6?>A>A@>A??;???A3=>:9>AAA
@1AI
CTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJIIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHHHHFFFFDEDDDDDDDDDDDDDDDDDDDDDC
@1AJ
TCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATG
+
@C@FFFFFGGHHHIJEEBHIIJJJIJJIIGIIJJJIGGIE<FHGBHDGGII7=AEFHDE@DFFECEDDDDCDDDDDD@CCDCDDDDDDDDDDDDDDDCCDC
@1AK
CCTGGGGCTGGAGGGAAGCTGTACTGTCCCACCTAACGTTGCAACTGGGAGACTTCCGGGGGCCTCACTGCTCCTAGAGCCCTCTTCGCTGACTGCCAAT
+
?<?BD??DDDA3AE?)<28EB:C@EE<DEI9)@8DBDBD3B:*.=)8.6(5'-)..74-5>;3<><:>AA>A>A>>:+:><7>83>:(5&0;?>4<AAAA
@1AL
CTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCT
+
@??B?ADAFHHFF:@FABG@FBBC?C<CBCDFG?DFDDDBHE?FDHEGCFB@;@FG7==C@@AEFE?DEC>A=@B?AC->>CCCABBBBB?<24499>+9@
@1AM
AGTAGAATCAACTGTGATTCCTGAATCTACAATAATGAGAACTCTACATAGTGGAGAAATAACCAGTCATGAGCAGGGCTTCTCTGTGGAACTGGAAAGTG
+
:??A;;D?FFFFF;A+CE@HHF<CFH9FF@<CB+A?EF<?9??FG4C<4?4?4)00?DF>BDBF<2B3=<@FDEGEE8A;CEEDDBDDB>>9AAA<;;?BA
@1AN
AAGAATTTGGTGTTGATGATTCTTATTCTGAACAAGGAGCACAAGACAGTCCGACTCATCTAGAGATGATGGAAAGTGAGTTGGCTGGGAAGCAGCATG
+
?<@1:=B;?FA?FG9C?D@ICHGGIGIIGGCHAHGGGIIHDFDEA)?FF09DFF@;;CG>F)=;77==AE@EEH;6.)77.6>>(.5355:(9???@>A
@1AO
CCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACA
+
@@CFFDFFGHFGHGJGGGIHIJIGIJIIGGGHBDCGGIJIGJJGHIJJJJJJJGDHAGHIJJIDBEFF@AAEDDDCCCCDDDDCD>CDDCDDCC@@CCD@
@1AP
TATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTT
+
CCCFFFFFHHHHHJJIIJJIJJJJJJIJIJJJJJJIIJIIJJJJJJJJIJJJJJJJJJJJJIJHDFFDEEEEEDDDDDDDDDDCDCBDDCDDDDDDDDCD
@1AQ
GAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGAC
+
CCCFFFFFHHHHHJJJJJJJJJJIJJIIJJJJJJJJJJJJJJJJJIJJJJJIHHHHFFFFEEBEEEDDDDDDDDDDDDDDDDDDDDDDDDDDDDDEDDDDD
@1AR
CCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGAC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJIJJJJJHIIJJIJJJJJJHHHHHFFFFEEEEEDDDDDDDDDDDDDDDDDD
@1AS
CAGACATGGAACGTCACATCAACGAGGAGGACACAGTGCCTCTTTCTCACTTTGATGAGAGCATGGCCTACATGCCGGAAGGGGGCTGCTGCAACCCCCAC
+
CCCFFFFFFFHHDIGGIIJJJIGIJIIIGIIJJJIGDGHGGIJIIJEHIIIIJJFGHDFEHGIEEHHECCDFCDCECB?BBDDDD<@DBCDDDDDDDDDBD
@1AT
ATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATG
+
@@@DFDDDFDHFHGFHH@CGIGHIJJJIGCGHE?BGFECEGGIBCHCBGGHIGIJIIIGEGHBCGCHCHGFBBABBCDDCDCDDEDD?@CCCCCDDCCCAC
@1AU
GTGTATATCAAATCAGCAAACAAATCAAAGCTCATGATGGCAGTGTGTTCACACTTTGTCAGATGAGAAATGGGATGTTATTAACTGGAGGAGGGAAAGAC
+
B@BDDFFFHHHHHJIJJJJJJJJJJJJJIJJJJJJJJJJJJJJGHFFHIIJIJIJJIJHGIJIJJJJJJJIJJJIJHHHFHHFFFFFFACDDDDDDDDDCD
@1AV
ACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCT
+
CCCFFFFFHHHHHJJJIJJJJJJJJJJJJHIJJJJJJJJJJJJJIJJJJJJJJIJJJJJJIJJIJIIIHHHHFFDDDDDDDDDDDDDDDDDDDDDCCDDD
@1AW
ATTTTGGATCACTTACCATCTGTAACAAAGGAATCATCACTTAGAGCAACTCAACCAAGTGAAAATGATAAACTTCAGAAAGAACTCAATGTACTTAAATC
+
CCCFFFFFHHHHHJIJJJJJJIHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJFHIJJJJJJIHJJJJJHHHHHHFFFFFEEEEDEDEEFEDDED
@1AX
CCCCACTGCATCATGCATCTCCAAACTCAACTCATACACCGAAACCTGACCGGGCCTTCCCAGCTCACCTCCCTCCATCGCAGTCCATACCAGATAGCAGC
+
C@CFFFFFHHHHHIJJJJJJIGIJIJJIJJJIIIIIIIJIGIJIJJJJGHJIJJJHGHFFFFFEEEEEDDDDDDDDDDDDDDDBDDDEDDDDDDDDDDDDD
@1AY
GAAAACTCTTGAGCTAAAGGATAAATTAACAACTGCTGATAAATTACTAGGAGAATTACAAGAACAGATTGTGCAAAAGAACCAAGAAATAAAAAACATG
+
CCCFFFFFGHGHGJJJJJJJJJJJJJJJJJJJJJJJIJJJIJJIJJJJJIJJJJIJJJIJJIJJJJJJIJIGIJJJJHHHHFFFFFEEEEEDDDDDDDDD
@1AZ
CTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTT
+
CCCFFFFFHHHHHIJHGIIJJJJJJIIIJJJJJJJJJIJJJIJIIJIJIJJJJJJJIGIIJHHHHHHFFFFFFCDDDDDDDBDDDDBDACCCDDDDD><9?
@1B0
AGACAGTAAAAATAAACAGGAATTAGAGTATAAAAGTAAACTTAAAGCACTTAATGAAGAGCTTCATTTGCAAAGAATAAATCCAACTACAGTGAAAATG
+
CCCFFFFFHHHHHJJJJJJJIIJJJJJJHHIJJJJJHIJJJJJJJJJJJJIJJIIJJJIJJIJJJJJJIJJJJJJIJJJJHGHHHFFFFFEEFEEEEDDD
@1B1
GGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACAC
+
CCCFFFFFHHGHGJJJIIJIJJIIJJJGFGHIIJJJBGIJIIJJJJIJJJJJJGJJIIIJJIJIIJJJHHHHGFFFFFDDEDDDDDDDDCDEECCCDDCD
@1B2
CCCCAATTGAAAAGAGAAATAAGGTTAATGAAAAACAGAGAAGCTGCTCGAGAGTGTCGCAGAAAGAAGAAAGAATATGTGAAATGCCTGGAAAAC
+
@@@FFFFFHHHHHIHHGIIIIJJJIIIIIJJJIJJIIJJJJJJJJJJGIJJIII=EFHIIJIGHGGFFFFFECEEDCDCCDCDDDDDDCDDDDDDD
@1B3
GGGAATTTTTGGGAAATATGAAAAGCCAAAATTTGTGCAGTGTTTAGCATTCTTGGGGAATGGAGATGTTCTTACTGGAGACTCAGGTGGAGTCATGCTT
+
CCCFFFFFHHHHHJJJJIJJJJJJJJJIJJJJJJJIJJJJHIHJJJJJJJJJJJJJJJJJJJJJJJFJHHHHHHHFFFFFEDEEEDDCCDDDDDDEDDDE
@1B4
CAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATAC
+
?==DDBBD:CF::CA<+23:CA:3A??2?C;GF<)86(/08?DFCC<<8=7@97..(6(.7((?;?@;6.>;@@35->>AB?B:(>>559@<<(((:4@
@1B5
CTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCC
+
CCCFFFDEHHGHGGFIIGGE@@EHGGIBFGGEGIEGIJIIIJJJ@@HBFGGGHGIF@GIGJGH>?EDEFFEDEEDEDDDD@BCCDDDDBDDDDEACCDDDD
@1B6
TTAGAAGACAGTAAAAATAAACAGGAATTAGAGTATAAAAGTAAACTTAAAGCACTTAATGAAGAGCTTCATTTGCAAAGAATAAATCCAACTACAGTGA
+
@@?ABD;D=CFF,2?EFDI<H@H?CFGF?B@AB*:CBBFEC?FED<?DGDDC<D@@FGIG@FG@F9CAFFEADEA>EEEAEFFEC@?@B@DCCCA3>-5;
@1B7
CTTCATTTGCAAAGAATAAATCCAACTACAGTGAAAATGAAAAGTTCTGTCTTTGATGAAGACAAAACTTTTGTAGCAAACATTGGAAATGGGTGAGGTTG
+
?@?DDDDDA<FHHIIIFEGIG<<CEGIIEC@FCCCGHIBH@DD;D@@BFGCGIIIFAGGII>GGCIFIGGECCCA;@GGIFEAE=?@;BCECC(9ABBCAC
@1B8
CAGCCAGATCCGTATCAGATCCTGAACCCGACCAGCAGTCGCCTAGCCAACCCTGGAAGCGGGCAGATCCAGCTGTGGCAATTCCTCCTGGAGCTGCTCTC
+
-;(2-@<34=)82;..=49>>>?4).:63?;;??(393)9</9=?9>9>9?5;>37>?0.98'32/665::(3262738<=32(+((6(((+(+((+:;/:
@1B9
GGCTTCTCGTCCTCAGAGTCGGAGAGCTCCAGTGAGTCCAGCTCCTCTGACAGCGAAGACTCCGAAACAGAGATGGCTCCGAAGTCAAAAAAGAAGGGGC
+
?=@FFFDFFFHHFGJEHGFHGEEEGIIIIIIIBDBHEGGIJIIHIGEBGCBGGEHHIHDHFFFF?B?BCDDDDACDCCCD@DDDBCDDACDDDDDDDBD@
@1BA
GAAAAGGGCCCCAGGCAGTTTTATGATGACACCTGTGTTGTCCCAGAAAAATTCGATGGAGACATCAAACAAGAGCCAGGAATGTATCGGGAAGGACCCAC
+
CCCFFFFFHHHHHJJJJJIJJJJJJJJJJJJJJJJIIIJIIJJJJJJJJJJJJJJJJJJIJJJHHHHHHFFFFDEEEEDDDDDDCDEEDDDDDDDDDDDDD
@1BB
CGAATTTATTAAGGGAAGAAGAATTTGGTGTTGATGATTCTTATTCTGAACAAGGAGCACAAGACAGTCCGACTCATCTAGAGATGATGGAAAGTGAGTTG
+
((7>5@9>1>:;<>@@??14=>4>@;6@(2.-(;13)6.>)<91.9))))<6>?87>7>7:;(.<36=)655:8=3((6=>6==3(919:(:7(,773;6;
@1BC
AGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCG
+
??@DADEAFBF<DGHCHBCHGGH?GFBHGGIGDG8DGIBGGIDGIIEEE@GFGIGIIGIEHCD=DHEGHFHGEFFFFCCA@ECCCCA@CCAACCA9A?<A>
@1BD
ACAAGAAGCTGAATTAGAGAGGCTGAGAACACAGCTTCTATTTAGTCACGAAGAAGAGCTTTCCAAACTGAAGGAAGATTTAGAAATTGAACATCGAATA
+
@;?D;BDDFA>FDFEB:C??;EF?DG;AE<FFE;?DD@9<BFEDB*9??6@D;6C3C68==;7@E@D=EEACFDDB?;ABCCC3;A@@;@BBBBBBBBBB
@1BE
CTTAAAGATAATTTAGGCATTCACTATAAACAGCAGATAGATGGTTTACAGAATGAAATGAGTCAAAAGATAGAAACCATGCAGTTTGAAAAGGACAATTT
+
CCCFFFFFHHFDHIA@AHGHICCEGEECFHHIIGIGGGIIEHHGCBHGHIIIIIIIGGHGIIIGGIIIGIIIIEHIGEHHEAAADCDF?CFCCCEACBCCC
@1BF
CCCACCAGCAGAAGGTGAACTTTGTCCCTCCCCATCCATCCTCCATGCCTGTCACTTCCTCCAGCTTCTTTGGAGCCGCATCACAATACTGGACCTCCCCC
+
CCCDFFFFHHHHHJJEHGIJJJJJJJIJJJJJIJIJJJJIIJJJJJJIJJJIIJIJJJGJJJJIJJJEIIHHHFHFFFDCDDDDDDCDDDEDDDDDDDDDD
@1BG
CCATGTTCAGCGTAGAGTCGCTGGAGCGGGCGGCGCTGTGCGAGAGCCTCCTCACTTGGATCCAGACATTTAATGAGGATGCACCATGCCAGCCCGAGGA
+
==;7<<,22,202<1@+2<)1)1?1))1::(5'',,8=0+:-7)))(88:23(8833++(+3+(+(8++:83:8+(++4;39(+(+++++(((2+)&)0&
@1BH
GTGAAGAGGAGCCAGGGTCGGATTCCAGTTAAATGGATGGCAATTGAATCCCTTTTTGATCATATCTACACCACGCAAAGTGATGTATGGTCTTTTGGTGT
+
?=?DD>D>DBD3CE@=E+3@E?E6DDBC:4?BBDEIE@CD<DIAAACCCABCDCEEADDICAD)=7?37?))?;;???:A5:;;:>;BD?:>AAAA>5(82
@1BI
AGAATACCATGTATATGCAGAATACTGTCAGTCTAGAGGAAGAGTTAAGAAAGGCCAACGCAGCGCGAAGTCAACTTGAAACCTACAAGAGACAGGTAGT
+
@@CFFDFFGGGFHGGGGGIIIJJGGDHDHIJGIIIJIHIIIIEFFIIIGHJJIJIFHIDEAF;BBHHFCDBCDDDDDDDDDDDDCCDDDCDDDCCB>@C:
@1BJ
TGTCAGTCTAGAGGAAGAGTTAAGAAAGGCCAACGCAGCGCGAAGTCAACTTGAAACCTACAAGAGACAGGAGGATCCAAAGTGGGAATTCCCTCGGA
+
@@@DDFFFHFDDBBFBFFHFJHEICHBHIJGHJDIGIJFEHIJIEECE?EEEHFFFFFDECEDEDDDDCDD9?BDDDDDDDD@ADDDDBDDCCCDDD@
@1BK
GAAGCCCACTATGACCCTGGAGGAGGGACTGCCATTGGCTGTGCAGGAGTGGGAGCACACCAGCAACTTTGACCGGATGATCTTTTATGAGATGGCAGAA
+
@@@DDDDDDD;CFEHHGEGEABE8AFG<GHFH9B9BFH;FH8??BFH@F=CGE;@HGEHEDBEECA@ACCC>CCBBB@;:C4@CCCCCC:>4>>>?C@<A
@1BL
CTCAAGTCCTTCCTCCGAGAGACCCGCCCTCGCCCGAGCCAGCCCTCCTCCCTGGCCATGCTGGACCTTCTGCACGTGGCTCGGGACATTGCCTGTGGCTG
+
@CCFFFDEHHHHGGJIJJJJJJJIJJJIJJJIIJJJJIJJIHHHEFFFEEECEDDDDDDDCDDDBDCDDDDDDDDDBBDDDDBDDDBDCDDDDCDDDDDDD
@1BM
GTTGATTTTGGATCACTTACCATCTGTAACAAAGGAATCATCACTTAGAGCAACTCAACCAAGTGAAAATGATAAACTTCAGAAAGAACTCAATGTACTT
+
@@@FADEFHHHFHJIHHIHGJEHIIIIGIGEHGIGIIIIGIJJJIJJJJJJJIJFGIHJJJJIJJJIJJJGEIJJIFHHFFEDFFFFEEDDCEDDCDDDF
@1BN
GGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGC
+
=?@DDABDFDBFF@FE?FFEDEFGIGGE?FGBFHG>FAFHIGEEGHGHAHFFFFCDFEAEC;@>CCABCCCCCCBBBBBB??<BB?CCCDCC:A@CC@C@B
@1BO
CAAATTCTCATTTTATTGCCTGGACTGGTCGAGGCATGGAATTTAAACTGATTGAGCCTGAAGAGGTGGCCCGACGTTGGGGCATTCAGAAAAACAGGCC
+
8:?DDDB?BFFFDAFAGGHG@CH>AB@AFA@8:CD;9?D><D<BBG@FGHGGG>FGBF3=FHCEGG;AE?B;AAB8,89<=999?CCCC@CCCBB??BBB
@1BP
CCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGC
+
@@CFFFDFDFHHHGGIJHIIGGIIIIJJBGHBFHGIGIDGIIIJIIFIIIJFCHIJGIIIIJIJIIEHGGHHEFFFFED@EB@BB?CBCDCDCCDDDB
@1BQ
CAAATTCTCATTTTATTGCCTGGACTGGTCGAGGCATGGAATTTAAACTGATTGAGCCTGAAGAGGTGGCCCGACGTTGGGGCATTCAGAAAAACAGGCC
+
@@@FFFFDDHFHGIJIGIIJJFIEIJJIFEEGGIIJIIIIGGIIJJJGGBBGH>GIGIIIJJIHGG=EHGFFDCBB@BBDDBBBCCADDDDDDDBD<BDD
@1BR
GAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCC
+
@@@FFDDDBFHHHJJIIGIGGCGHGIIGIIGHFBGGHJJJJIIJJIGHIHJJHHHFEHFFDFBCECCEECCDCCCCCDDDDDC@D:@CDCCBBDDDDDCCD
@1BS
AAACAGCAGATAGATGGTTTACAGAATGAAATGAGTCAAAAGATAGAAACCATGCAGTTTGAAAAGGACAATTTGATAACTAAGCAGAATCAATTAATTTT
+
@@CF?D>DDHDHHF>FHGCFFHEBBEFHGHFHHDD?BGHIGHDHGIBHIC@FCDFGIBFDHCHGIIJ@GGGADGIEHEHCHFFCDFCCCACCDCD@CCDDD
@1BT
CGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTC
+
CCCFFFFFHHGHGIIJJJGGIJIJJIJJIJGJIJJJJJJJGIIJJIJJEIGJJJJIIJIJIJJHHHGFFFFFCDDDDDDDCDDDCEDCCCDDCCCC?@DBD
@1BU
CAACAAGCTCCCCGGCGAGAAGCTGGGCCGCGTGGTGCACATCATCCAGTCACGGGAGCCCTCCCTGAAGAATTCCAACCCCGACGAGATTGAAATCGACT
+
CCCFFFFFHHHHHJJJJJJJJJIJJJJJJJIJHFF?BEEEEDDDDDDDDCDDDDDDDDDDDDDDDDDDDDDDDDDDEDDDDDDDDDDDDDDDDDDDDDDDD
@1BV
TTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCC
+
C@@FFFFFHFHHHGIJIJIIJJJJJJIJIJHHIJJJJJJIJIJJEHIGJGHIIDGCDHIGEIGIEHGHFFDDCDDDCBCEDDCDDFD6>BDDBBDD<BDD
@1BW
CGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTAGGGCACTGGTGCTT
+
CCCFFFFFGFDDHGEDEHEHHIIJIIE@GGBFEEGIF9:DGIJJJJGIGIBFF8?CFGHHHEH=DEFFEA?CCDDCDCCCCD@BD8<(2<<?@CDD:CCDD
@1BX
CTCCTGTGACTCTCACCTCTCAGACAACTAAGACAGATGACCCCCAATTGAAAAGAGAAATAAGGTTAATGAAAAACAGAGAAGCTGCTCGAGAATGTCGC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJIJJJJJJJJJIJJJJIJJJJJIJJIJJJJEHHJJJJJJJCHIHHHHHHHFFFDEDEEDDDDDDDDDDDDDDCDDD
@1BY
GTGAAAATGAAAAGTTCTGTCTTTGATGAAGACAAAACTTTTGTAGCAGAAACATTGGAAATGGGTGAGGTTGTTGAAAAGGATACAACAGAACTCATGG
+
CCCFFFFFHGHHHJHIJJJJJJJJJJJJJJJJJIJJJJJJJJJHIJJJJJJJJIIJIJJJJJJJIFGIJJHIIIHHHHHHFFFDEEEEEDDDDDDDDDDD
@1BZ
GAACGTCACATCAACGAGGAGGACACAGTGCCTCTTTCTCACTTTGATGAGAGCATGGCCTACATGCCGGAAGGGGGCTGCTGCAACCCCCACCCCTACA
+
CCCFFDFFHHHHHJJJJJJIJJJJJJIIHIIIJJJJJJJJIJJJJJJJIJJJJJJGJJJJIJJJHHHHFFDBDDDDDDDDDDDDDDDDDDDDDDDDDDDD
@1C0
GTTTGAACAGTTGTCTGGATCCATTTTGTGGATGGCACCAGAAGTCATCAGAATGCAAGATAAAAATCCATACAGCTTTCAGTCAGATGTATATGC
+
@@?7ADD;BDDHHFGH@GH>E>FBHHGH2AE???FCB??DFG>B?FFC?DGCBGBHHDGIGGHHIIIEGGHDG>DECEFA>@CBCD@DA;@@CC@C
@1C1
GCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCC
+
CCCFFFFFHFGHHJIJJFHHIIJJIIJJJJJGIJJJJJIJJJJIEIJJJJJJIJEHHGHFFFDDDDEDDEDDDDDDDDDDDDDDDDDDDDDDDDDCDDDDD
@1C2
AAGACAGTAAAAATAAACAGGAATTAGAGTATAAAAGTAAACTTAAAGCACTTAATGAAGAGCTTCATTTGCAAAGAATAAATCCAACTACAGTGAAAATG
+
@@@FDFFDHDDHHJIJIIGHIIIIGIGIIHHIIGGHJ?HGHHJJIIEIIFDEHGHGGHIFGEIEIIGGAGHJIIJJJJIHGHHHGEEEFFDDE;ACEDDDD
@1C3
GAGAGGCTGAGAACACAGCTTCTATTTAGTCACGAAGAAGAGCTTTCCAAACTGAAGGAAGATTTAGAAATTGAACATCGAATAAATATTGAAAAACTTA
+
@CCDFFFFGFFHHIIIJIIJIGGHIHGAHFHIIJIGHDDGDHEGHGGHEHGGGIBDGGAFHHGIEHHJGHHHHHFFFFFDEEEDDDDEFEEDDDDDDDDC
@1C4
GTCCAGGCTCTCCGAGGACGGGCTGCATAGGGAAGGGAAGCCCATCAACCTCTCTCATCGGGAAGACCTGGCTTACATGAACCACATCATGGTCTCTGTCT
+
@?@DABBD>F?CBGCAF>F8CA:0?8*?9*??*BDA:=.5@@C9=AEFCF;@9;766;AABBB8<9A<59993<BA3>>AA@BBBBBBB@A@(4:::AB@>
@1C5
TGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGG
+
@@@FFFFFHHFHGDIIGGIJIJJJFHIJGIFIGJJJGHGHHIIIEGIJ@BHIIJAEHEDFFDDEDECCDCCCCDD<>CBCC>@CCDDDCCB@CDDDDDDBB
@1C6
GAGAAATCATAAAGACAGCCAGTTCGAAACTGATATAGTACAACGAATGGAACAAGAAACACAAAGAAAGTTAGAACAACTCCGGGCAGAGCTGGATG
+
C@CFFFFFGHGHHJJJJJJJJJHJGIGIJIJJIGGIIJGIJIIJJJIIIJGGGIJIJIJGIGIJJIIHHHHHFFFFDFECEDCBDDBDDDDCDDDDDD
@1C7
AGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCAC
+
@@@FFFFDBFHFHIJBHGIIEGGEGHIJIJCEHIIJJIJIJJGHIACGABHBEGEFFFFC?AECDDE>CDDDCCDD?BBBDDDDDDBBDDC@ABCDDDDCC
@1C8
GGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATAC
+
@@@DDDAD:A?DDFGI<GGH@C?DFC@AB+)1:?D3?<?38B<G*?<DF?@FGCF=F;F6ABHEEE>>@CCC;>CC;>AC;A:,9<(5??<A84?CCCCC:
@1C9
CCGGACAAAAGGCCGGTGTTTGCGGACATCAGCAAAGACCTGGAGAAGATGATGGTTAAGAGGAGAGACTACTTGGACCTTGCGGCGTCCACTCCATCTG
+
???D;=D;:2<2::1<<C:?D94@D>ADDCEC>CD3.83@372CCDD>DDD;;;@?>>A>AA>??????>>3:>>(5:3<>A305-9990<3>><:+:>:
@1CA
TGAAGCAGAAGTTACAAATTACAAGATAAAACTTGAAATGTTAGAAAAAGAAAAGAATGCTGTGTTAGACAGAATGGCTGAATCACAAGAAGCTGAATT
+
@@@FFFFDHFHBFGIIGGIGGEGHGHIIJJJGGJJIIGGIGGIIJIEHJGEGGEGGIBDHII@GGGIGEHHEIJIHHHHEDFFDECCEEEDCDCDCCCD
@1CB
CTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGT
+
CC@FFDBDHDFHGIGI@AEHI@HGCGHGIIIIGGGFH@DGGIIE><FGGFHHI=FG@ECGGAGGIGGECHHHEFEDBAEB6;=;AB:CCCCCCCBBC<CB(
@1CC
CGTTGGGGCATTCAGAAAAACAGGCCAGCTATGAACTATGATAAACTTAGCCGTTCACTCCGCTATTACTATGAGAAAGGAATTATGCAAAAGGTGAGC
+
@@@DFFFFHHHHHIGGIIJJIGIIIGIGGIJJJJJJJJJJIJIIIGIIJJJJJIIJFHHIIJHHGFFFFFDDEEEDEDDDDDCDDDDDDDDDCB:@CDD
@1CD
CACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCA
+
?@@FFDDDABDBBGGBHICC>C?;;FHGHIGGBHGGIIBGIG<??GFGIIDGFGAGA@>@HHHHEEEF?7@@>@A7AACCBBCBBCBACCCC>:4@>ACC
@1CE
NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN
+
###################################
@1CF
CAAAGCTTTCCCCCTCCTCTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN
+
<<<????@?>??????@??=#################################################################################
@1CG
CAGATCCTCACTCATCAACAGCAGCTTGAAGAACAAGACCACTTATTAGAAGATTATCAGAAAAAGAAAGAAGACTTCACAATGCAAATTAGTTTCTTGC
+
CCCDFFFFHHHHHJIJJJJJIJJJIJJIIIJIJJJIIJIIIIIIJJIJJIJJJJJJJJJJHIJGGIJJIIJHHHGHFFEFFEEEEEEDDDDDDDEDDDDD
@1CH
CAGAGACTGTCTGATCTTTCTGAACAATTGAAACAGAAACATGGTGAGATTAGTTTTCTAAATGAAGAAGTTAAATCTTTAAAGCAAG
+
@C@DFFFFDHHFDGHIGIIDHIHHGIJJIGEIIIIIIIEIIJJI:BDDGHIIHDGEIGGGIJJGIIIIJJIIJJJJJJJJJHHGHHHF
@1CI
TGAGAAAGGAATTATGCAAAAGGTGGCTGGAGAGAGATATGTCTACAAGTTTGTGTGTGATCCAGAAGCCCTTTTCTCCATGGCCTTTCCAGATAATCAGC
+
CCCFFFFFHHHHGJJJJJJJJJJHHJJJJJJJJJJJJJJJJJJJJJJJJGHIJBHFGFHIEIJIJJIJJHHGHHFFFFFFEEEEEEDDDDEDDDDDDDDDD
@1CJ
GGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGC
+
CC@DFDDFHFFHFIGGGHIEGGGGGJEHGHJGGFHHADFHGHIIGBHHHGFEDCDBFFDCCCEEDDBDCCCCCCBBD@@BDDDBDDDCC>CCCACCCDCBD
@1CK
CCAGAAGCCCTTTTCTCCATGGCCTTTCCAGATAATCAGCGTCCACTGCTGAAGACAGACATGGAACGTCACATCAACGAGGAGGACACAGTGCCTCTTTC
+
@@@DDDDDF;FFF><AGFCCH9FAFGAHB?A*:F<?1?1:?:?6)00999?F<*)8888=8.@8C774..(-77.;?;95;@'=8(,(,5<,4>:44>BA4
@1CL
CTCTCCTGGTCTCTCAACAGGCAAAACGGGAGGAGGAGCGCAGCCCAGCTGCCCCACCACCTCTGCCTACCACCTCCTCTGGCAAGGCTGCAAAGAAAC
+
CCCFFFFFHBFHHJJIJJJJJJJJJJJJJJJJJIJJJJJJIIJJJJJIHHHHFFFFDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDCDBDDDDDDDD
@1CM
CAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCG
+
?=1AD:BDFCFDFECFFFCFAAG@@GFIBFFE;4?;FCDFCDFEFFDECFFAD=CF7@D>ACCEAEEFF@???;@>>@@BB@88?@BBB?B@4>:@AB:@?
@1CN
CTATGAACTCCTTCAGCATATTCTGAAGCAGAGGAAACCTCGGATTCTTTTTTCACCATTCTTCCACCCTGGAAACTCTATACACACACAGCCGGAGGTC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJIJIJJIJIIIIHIJIJJJJJJJJIIIJJJJJJGJJHHHHFFFFFEEEDEEEEDDDDDDDDDDDDDD@D
@1CO
CAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGAC
+
C@@FFBDDFDHDHIGGGHEHEIJJGIGIICHDHGGEDBHIG@DFFHIIIJGGGGGGGG>@AGGHH>H??B;B?B;C;>A;@@C>>CDDDC@ABDB<ADDCC
@1CP
TGTAGAGCCCACACCTGGGAAAGGACCTAAAGGTGTATATCAAATCAGCAAACAAATCAAAGCTCATGATGGCAGTGTGTTCACACTTTGTCAGATGAGA
+
@C@FFFEDHGHFDGBHJIJHGIIJJIJJJIJJICDDGIEGGGIIIIJ9DFFHGGGGGGEGGGGIIJJHGEHAECFBD@D6>CEEEDDDDCA:CCC@CCC@
@1CQ
GCAGAAATAAAGACAACAAATGAAGTTGTTTTGGCTGTGGAGTTTCACCCAACAGATGCAAATACCATAATTACATGCGGTAAATCTCATATTTTCTTCTG
+
+=8BBDA?CF<AFG>ACAEGEFF<?FHCACFEDBGICGFIIB:DDGIIIFFE;C;8=@FE;FGE@=@=DAE=EF;=;?B83<?A@B@3;3>BBBD:>::::
@1CR
CTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAA
+
CCCFFFFFHHHHHIIJJJHIJJJJJJJJJJJJJJJJJJGIJIJJJJJJJJJJJJJJJIJJJJIHHFFDEEEEDDDDDDDDDDDDCDDDDEDDDCDDDDDD
@1CS
CAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCC
+
CCCFFEFFHHHHHJJIIJIJJJJJJJJIJJIJJIJJJJJJJJJJIJIJJJJJHJJJJJIJJJJIJJJJHHHHHFFFFEEEEEEDDDDDEEDDDDDDDDDDD
@1CT
ATAAAGTTAATGAATGTGGCAATAAATGAACTGAATATAAAATTGCAAGATACTAACTCTCAAAAGGAAAAACTCAAGGAAGAACTAGGACTAATTTT
+
CCCFFFDFHHHHHJJJHJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHGGFFFFFEEEEEDDEED
@1CU
CCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGG
+
@@@FFFDDHHHHGBDBEEHGIGIGGGHIEDBH<FGGEHJJIGGHHGJJJEEADDGGEAHHGF@CDEFE@C@CCCCCB@BB55?>CCDD@ABBBA<AB9A<>
@1CV
GTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTAT
+
CBCFFFFFHHHHHJJJJJJJJJJJJIJJIJJJIIJIJJJJJJJJJJJJJJGJIJJJHHHHFFFEFEDEEEEDDDDDDDDDDDDDDDDDDDDDDEDEDDDDD
@1CW
CTTTTTCATTTGCTGAAAAAAACTTTGAAGTTAACTATCAAGAGTTACAAGAGGAGTATGCTTGCCTTCTCAAAGTAAAAGATGATTTAGAAGACAGTAA
+
@@@DDDDDDBB?ACC?CFIGIGBDDC<CDB9?CGDB?BGDDD@BHA@?DFE;==FG)=CF@FIHCHIE>?EAAD>BDCC@>B;>>;;AC;;C;;5??5@:
@1CX
CCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCC
+
CCCFFFDFHHHHHIJJJJJJJJJJJJJJJJJJIJGIIJJJJJJIJJJJJJJJIJJJJJIJJJHHHFFFFFEEDDDDDDDCEEDDDDDDDDDDDDDDDDDDD
@1CY
CCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGC
+
CCCFFFFFHHHHHJJJJJJJJJJIIIJJIJJJIJJJJJJJIJJJJJJJJJJJJJIJIJJJJJIJHHHHHHFFFFFDDDDDDDDDDDDDDDDDDDDDDDDDD
@1CZ
CTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTT
+
CCCFFFFFHHHHHJJJIJJJJIJJJHIJJJJJJJJJJJIJIJJIJJJJJJIIJJJJJJJIJHHHHHHFFFFFFDDDDDCDDDDDDDDD@CDCDEDDD9><B
@1D0
GTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGC
+
CBBFFFFFHGGGHIJJIJJJJIIIJCFHGIJJJJGIIJIIIIIIJJJIJJJIHHHHHFCDFFFEEEEEDDEDDDDDDD>CDDCDDDDDDDDDDDDDDDD
@1D1
CCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGG
+
CCCFFFFFHHHHHJJJJIJJJJJJJIJJJJHHJJJJJJJJJJJJJJJJJJJJJJJJJJIJJIJHGHFFFEFFEEEEFEDDDDDDDDDDDDDDDACDDCDDD
@1D2
TATGAATTGATGACTGGACAGTTACCTTATTCAAACATCAACAACAGGGACCAGATAATTTTTATGGTGGGACGAGGATACCTGTCTCCAGATCTCAGTA
+
@@?BDDDDD??BCFAGG>;CEHABHHHIEHCEHHEBE@?FA?FGDBGHE@G=D;;8CBHIII>@AHG.=EB;AB9>>>;;@AAC>:5@AC3:>?>>CC3:
@1D3
CCTGAAAGCATCATGTACCGGAAGTTCACTACAGAGAGTGATGTATGGAGCTTGGGGGGGATCCTTTGGGAGATCTTCACCGATGGGAAGCAGCCATGGTT
+
;8;((.9.)22).9@@:.@99-(8@@)18@<=).).)-<=:89>91)))..3=)-75=&0:9<6:((+55:<08++3/::4(5569(+22((+86+::7(8
@1D4
GTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGGCTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACC
+
++1<?,7=<+2<?AA+<?7<=+<+<?;+:)?=A*??=<*:?7*?0)*=A=:'''(8.))).).7=A)>).7..>;>>>>>>;;=;===3;(;(,(9=9(97
@1D5
CTTTGAGACCCTGAAGCCGTCCACACTGCGTGAGCTGGAGCGCTATGTCACCTCCTGTTTGCGGAAGAAAAGGAAACCTCAAGCTGAGAAAGTTGATGTG
+
CCCFFFFFHFFDHGGAHGGHBDFHIEGHFG@FHHEGIIHHCGBGEHIGGEGHIIH>E=EBD3?BBBBA?AACBDDCDDDDD@C@CCABACDCDCDCCD>@
@1D6
CTACACCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATGACATCTCCTGTGACTCTCACCTCTCAGACAACTAAGACAGATGACCCCCAATTGAAA
+
CCCFFFAEBFHHHJIIJIGGIJGIIGGGIJIJGFEGBGHEHGGIIJEIGGEHEGIEGGIIDHEIIIJIIJJJBGDEEHFEFFDDDEECDDDBCAC:AC
@1D7
CACAAACTGTGGTGATGACATCTCCTGTGACTCTCACCTCTCAGACAACTAAGACAGATGACCCCCAATTGAAAAGAGAAATAAGGTTAATGAAAAAC
+
??==+2AADDCDAC<EFFIIHI9HHFDFC>BEGIBEECGIIEEFAFFF@FEFDFIIB@>DFG@@FAEEE;AEECD>;B;AA6>BA@BB;5>>;>>BB;
@1D8
TCGAAACTGATATAGTACAACGAATGGAACAAGAAACACAAAGAAAGTTAGAACAACTCCGGGCAGAGCTGGATGAGATGTATGGGCAGCAGATAGTGCA
+
@@@DFDFFHHGHHIICEHHGGIJIJIJJJIIIGIJJJJIGIIJGJJGCHGIIIFIIGIJIIII<BDDDFEEE>@CCDACA5>;ACD@CDBBBC>@CCECC
@1D9
CCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAAC
+
@@@DDDDDFDHD?CAEEB?B@FB@GGGEHIGG>EBGCFD;FH@G@@BFCBDBF9?B==8B=FA8-5::777;;?>>A@>;;>;;>>>>;:@ACCCC?A?C
@1DA
CGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCT
+
CCCFFFFFHHGHHJJJJJJIJIIIIIIJJEGDFHIIIJJHIIIIJJJJJAAFHGJEGGJIIIIIIIHHHHHHFFFFDDDDBBCDDDCDDCCDDDDDDDBDD
@1DB
CATGCGGTAAATCTCATATTTTCTTCTGGACCTGGAGCGGCAATTCACTAACAAGAAAACAGGGAATTTTTGGGAAATATGAAAAGCCAAAATTTGTGC
+
@@?D=DD1CD?CFABA@EHE:A<AFFF<34?BECG;DG<@@DFGHB)=;F;=;=7@7=CE;;?7((;>>@6;B@<>@A:;3>:@:((23392+44++3:
@1DC
CCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCAC
+
CCCFFFFFHHHHHJJJJJJEIIIJJJIJJJJJJJJJJJJJJJJJIJJJJIJJJJJJJHHHHFFFFEEDEDDDDDDDDDDDDDDDDEDDDDDDDDDDDDDDD
@1DD
GAAGAAAAGGAAACCTCAAGCTGAGAAAGGTGATGTGATTGCCGGCTCCTCCAAGGTGAAGGGCTTCTCGTCCTCAGAGTCGGAGAGCTCCAGTGAGTCC
+
=+=<+<AA>C3CB;C;+7A@73++2+<A3)@****:1**?4:?0A(.:;;)>)>=(.).7)7:1(;.)),(,=535((--52;''&+(+3::3++(3(38
@1DE
GTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACC
+
CBCFFFFFHHHHHJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJIJJJIJJJJIJGIJJJJJJJHHHHHFFFFFFFCEEEEEDDDDDDDDDDDDDDDDDD
@1DF
CTATGGAGAAAAGTGCCTGTACAATGTCAGTGCCTATGATCAGAAGCCACAAGTGGGAATGAGGCCCTCCAACCCCCCCACACCATCCAGCACGCCAGTGT
+
CCCFFFFFHFBHFAGGIII?FHIGHIHHJICHHIJIJJJJCHHIGIIEIIIIGGHIGIJJEBFHHCCGHJIHHFHFF>BBBDDDA@ABDDDCB5>?BBDD>
@1DG
GGGAACTCCGGGACCCTTGGGTGTGGAGAGGAGAGGGTCTGGGAAGGTTATAAACCAGGTATCTCTACATCAGGATGGCCATCTAGGAGGCGCTGGGCCTC
+
B@@FDFFFGHGGHJJIIIIGICGDFGFGHIJJJIJJJBGGGGIIIJI@CHEEHHEFFDD6>CADEECCDDDDCCCCABACDCCDDDD:CB?@BDBD?@BB?
@1DH
TGTTGTCCCAGAAAAATTCGATGGAGACATCAAACAAGAGCCAGGAATGTATCGGGAAGGACCCACATACCAACGGCGAGGATCACTTCAGCTCTGGCAGT
+
CCCFFFFFHHHHHJJJJIJIGIJJJIJIJJJJJIJJJJJJJJJIJJJJJFGIIJIJJJJJJHHHHFFFFEEEDDDDDDDDDDDDDDDDDDDCDDDDDDDD<
@1DI
CCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACAC
+
CC@FFDDFDFGGGJJIGIIIJJIJIIIGHGIJJJJJJIJIJGIIJJIJHGIJJIIJJGEFGHIFGFEEBDFFFFFEEEEEEDDCCCDACCCDDDDDDDDDD
@1DJ
ATTCTTCAGTATGCACAGACCTCTGATGGACAGCAGATACTTGTGCCCAGCAATCAGGTGGTCGTACAAACTGCATCAGGAGATATGCAAACATATC
+
@@@F?DDDFFFFAHEGHBGH?HGGGGB>FFGIEE@G>9BBHEGIEGHGG8BF9B?DF?=CF'7;-=;CGC=7A=CB;@D;;A?CAAAA>@>AB@>AC
@1DK
GGCAATTCACTAACAAGAAAACAGGGAATTTTTGGGAAATATGAAAAGCCAAAATTTGTGCAGTGTTTAGCATTCTTGGGGAATGGAGATGTTCTTACTGG
+
@@@DDDFFHFHHFGIGJJIJJJJIIGIJJIJJJJII9FEIDHGIJJJIJJIIHFFGIJIIGIIDGHGEHHHFHHFFFFFFDDDDDD>A>CDACDDDDCDDD
@1DL
TGTGAACAGAAGCAAGAGTACATCCAAGCCATTATGATGATGGAGGAATCTGTTCAACATGTTGTCATGACAGCCATTCAAGAGCTGATGAGTAAAGAATC
+
@@@FFFFFFHGHHJGIHJHIJIIIJJJIIHHHHFGHIHIGGIIGIIIJJJJJGIFIIEGHJJJIJGIIIHIIJJFHHHGHHH?BDFF@CE@C@CCDDCBDD
@1DM
CCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAG
+
CCCFFADDFHHHHJJGIJJIJJFJIIJJJGGHJHIHGIIHIIJEHIIGIGIIGGGGIIJJJIJIHHHEEHFFFFDFEEECEDDD@DDDDCEEECCECDD
@1DN
CCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCC
+
@B@DDFFFGHHHDFGIIIJGIIIHIJIIJEIEEIEGGIIIGIHGIGJIJJJIIJJIJGIIJJICEHCHFFFFFCDDCECDCCDDDDCCCDDDDDDDDD:@C
@1DO
CGTCCACACTGCGTGAGCTGGAGCGCTATGTCACCTCCTGTTTGCGGAAGAAAAGGAAACCTCAAGCTGAGAAAGTTGATGTGATTGCCGGCTCCTCCA
+
@?@D?=D??F<A?1C;CGF?9<<EC1)::9???DG99??B*9/8*-4A8@EEAE>A;??76;;>CC;>;5=5:?3@@>35;@>@3>::A9&5-<B?<A?
@1DP
CTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTAT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJIJJJJJJJFHIJIJJJJJHAHHHHFFFFFFEEEEDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDD
@1DQ
GCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGT
+
?;@;DDDDFHFFH>CCFEHIGG<@CGFAHGBFFHHEHGGIHBADFHDEABFCGHGEHII9CDG=A;=?EHB>CC>?AC>C@C:A:<?9A9?44>C>:A@@4
@1DR
ATGGAGAATGCTTTAAGGTCATATTCAAATATTACAGTTAATGAAGATCAGATAAAGTTAATGAATGTGGCAATAAATGAACTGAATATAAAATTGCA
+
C@@FFFFDBFFFFIIGHIFIHHIIIJIIIIJIIIJIJJJJGIICGGDAFFHJIIJJJFGIJJJIGI@BCFGGGIIJJGJJGGIIJGHHHHFGFDFFFF
@1DS
AGAAAAGGAAACCTCAAGCTGAGAAAGTTGATGTGATTGCCGGCTCCTCCAAGATGAAGGGCTTCTCGTCCTCAGAGTCGGAGAGCTCCAGTGAGTCCAGC
+
<@@DDDDDHFF3+?FE<FF<EF?A?FE2ACF<E1?GFHC@?DDFG>??@CCFE>FA:F>;<5?6=7???B=5@AC@C;5>?=?/<<CCCCC:4>C:3>CC>
@1DT
TGAAGATCAGATAAAGTTAATGAATGTGGCAATAAATGAACTGAATATAAAATTGCAAGATACTAACTCTCAAAAGGAAAAACTCAAGGAAGAACTAGGAC
+
?@@FFBDDDDDFFIEDCEEBFHD@FHCABFGIIIGCCFHHEHIHGEGHHGIHEGHHCGGHGHIIIGI@FCDEHGBC@@CGHEEAABCDC?@@;@?>@ACCC
@1DU
CTTAAAGATAATTTAGGCATTCACTATAAACAGCAGATAGATGGTTTACAGAATGAAATGAGTCAAAAGATAGAAACCATGCAGTTTGAAAAGGACAATTT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJIJJJJJJJJJJJJJJJJIIJJJJJJJJJJJJJJJJHHHHHFFFFFFFEEDEDDDDDD
@1DV
CCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCC
+
@@@FFD?DFHHHHHBHGIJGFBEGFHGHECDFDFBGBFGFHHA9?DDHIGEIDEHIJGDGHIFHFFFDDDCCDD?B?CCDDDDDDCBDDBDBDDDCDCCDD
@1DW
CCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCC
+
CCCFFFFFHHHHHJJJJJIJJJJJJJJIHIJIJIJJJJJJIIJJJIJHJJIIJJJJJIJIJIIJ@GIJHHHHHFFFFEFDEDEEDDDDBDDDDDDDDDDDD
@1DX
AACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTAC
+
@@@FFFBDHHFHHAGIIIGIEG3EGGDHIIIIDIIIIIIII@FHEHIIIIIIGGGIGGIGHIGHFFF<BDFECACDEDDCDCCCCCB@?>CCCCBCCC?C>
@1DY
AGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTTATGGGCAGG
+
@@CFFFFFHHHHHJHIJJJJJJJJJJJJJJGJJJJJJJJJJJJJJJIJJJJJJGHJJJJJJJHHFFFCDDDDDDBDDCDDDDEDDD9<>BDDDDDDDDDD
@1DZ
GTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGC
+
CCCFFFFFHHHHGJJJJGGIJIIJJJJIJIJJGIIHJDHGIJJJJJJGHIJIGHHFFFFECEEEEDDDDDEDDDCBDCDDD?DDDDDDDEDDDDDDDDDDD
@1E0
CGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCG
+
?<7DDD?DDHFHFBG?F<<::DBHCGDGIEHI@F?FFBA:AGBDCEF>BB?@CCDDCCCCCC;;@A95<>>CCAC9@@B>?885?@<<CC:>ACCCCCCC5
@1E1
AGATAACTGTGTCCAGAGGACCCCCAGGCCATCCGTGGATAATGTGCACCATAACCCTCCCACCATTGAACTGTTGCACCGCTCCAGGTCACCTATCACG
+
CCCFDDFDDHDDDBFHG?;FHCHIDH?FFGHB@DGD?DFGCBFCGHEGGIBGCG@FHIBEHHFEBBDBDF;;;>@ACCCC?;=BBCAC:>A@CCCCACC@
@1E2
AGGAACCACATGCAGACAAAGATTTCTGCCAAGAAAAACAAGTGGCTTACTGCCCTTCTGGCAAGCCTGAAGGCCTGAACTATGCCTGTCTCACTCACAGT
+
CCCFFFFFHHHHHJJJIJJJJIIJJJJJJIJIJJJJIJIJJJDFGIIGIIJCIIHHIJIHIJJJJJHGHHHFFFFEDDEEDDDDDDDDCCDDEDDDDDDDC
@1E3
GAAATGGAGAATGCTTTAAGGTCATATTCAAATATTACAGTTAATGAAGATCAGATAAAGTTAATGAATGTGGCAATAAATGAACTGAATATAAAATTGC
+
BB@FDFFFHHHHHIJJJJJJIHJJJIJJIJJJJJJJJJJJIJJJJJJJJIJJJIIIJJJJGIJJJJIJJJEHIIJJIJJIIJJJJHHHHFFFFFFFFECD
@1E4
CCTCTACAACCCCACGTCAGAGTGTGGGATTCTGTTACTCTATCCACACTGCAGATTATTGGACTTGGCACTTTTGAGCGTGGAGTAGGATGCCTGGATTT
+
@8@DDFFFDFCFHIIGHFEGHGA?C@GGFEGGIGBDHIG<BDGHEHG>FBCGFH<CGGFHIHGHHIGF@>EEDDFFFCEC@?B@BCCCC@>@BC@ABBCCC
@1E5
CAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTT
+
CCCFFFDDGDHHHGHIIEGGIJHIJFIIIJJJJJIIIIGIJJJIIJIIIJJJJJJJJJJJJIJHHHHGGFFCEFECCEEEEDDDEDDCDDDDDDDDDDDD
@1E6
AGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATG
+
@B@FFFFFHHHHFIIJJGJIJJJIJJJIIJJJJJJJJJJJJJIGGIJIJJJJJIIJJJHHHHHFFFFFFDEDDDD@BBCDDDDDBDDDDDDDDDDDCDDDD
@1E7
AGGAGATATGCAAACATATCAGATCCGAACTACACCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATGACATCTCCTGTGACTCTCACCTCTCAGACA
+
@@?BBDDAFH?FDHGIIGHIIHGHIIIIGGHGIHHHHDEGGGIIGICGIIGHGIGHIIIGHF=@CDHIGIHHHHHFEEEEBDECCCCCCCBABCCCCCCB
@1E8
AACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCC
+
CCCFFFFFHHHHHJJJJJIJJJJJJJJIJHIIJJJJJJJJJJJJJJJJJEGIJJJJJJJIJIJJJJHHHHHFFFFECEEDEEDDDDDDDDDDDDDDDDDDD
@1E9
GCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTAT
+
<?@DDADDHHDBBFEGGGI@CFC@H@GDCBHBBCA?E?;:C??9?@;FEDEF@FGGHB;CHEGEEGCCEEEHEEDEEEECCCCCCCBBCBBCCCBACBCCC
@1EA
GGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACAC
+
CC@FFFFDFFHGGHGIIJIJIJJJIJGGCHEHIGHJJJJIJJIIJIGGIJJIIJJFHHJJIJIJIHIIHHHHHFFFEFDDEEDDCCDCCCDEDDDDDDDD
@1EB
CAAGATTGGAGACTTCGGGATGGCCCGAGACATCTACAGGGCGAGCTACTATAGAAAGGGAGGCTGTGCCATGCTGCCAGTTAAGTGGATGCCCCCAGAGG
+
@@<DDDFDHBHFAEGIBEHGAHIIIGGGGIIIIICGAFDGIIGEGHHHDDFFDBCCCDEDD@B??B5>C@CC@C>A>?CCCDDEC(:AACCBC?BBD@?<@
@1EC
CTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATG
+
@@@FFFADHHGHHJJIGIJGIJJIIIGIJIAHIGEFHIIJJJJIJIJIGGIJJIJJHHHGCHFFFFDDBCDDDDDDDDDCCDDDDDDD>CDBDBBBBCCAC
@1ED
AGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJGIJJJJJJJJJJIJJJJJJJJIJIJJJJIJJJJJIJJJJJJHHHHFFDDDDDDDDDDDDDDDDDDDCDDCDECDD
@1EE
AAAAGAAAAGGGTACACTTGAACAAGAAGTTCAAGAATTACAACTTAAAACAGAATTGTTAGAAAAACAGATGAAGGAAAAAGAGAATGATCTTCAAGAA
+
CCCFFFFFHHHHFGIJJJJJJJJJJJJJJHIJJJJIJJJJJIJJJJJJIJJJIJJJJJIIIIJJJJJJJJGIHHHGHHFFFFCDEEDCDDDDEDEEDDDD
@1EF
CAGTGCGGCCAGCCAAAGCTTTCCCCCTCCTCTGATGATTAAACAGGAACCCAGAGATTTTGCATATGACTCAGAAGTGCCTAGCTGCCACTCCATTTAT
+
@@@?DDDADDHDHIIIGHEHGIGIIIIGFG@FEHGIGIIIIIIIIFIIIIIIGIIHHHBHFFFFFFFEEEEDACDCC>CCDCDCDCACBCDACD@:@DEE
@1EG
CTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGC
+
CCCFFFFFDHHGHJIIJIJJIGIJIJIIJJJIIGIIJIGHIJGCGCGGEIIIGHIIIJGGHEHJFEGEFFEF>>BC;CCCEED@CBDBABDCDDAABDDC
@1EH
GAAGCATTGCCCCTCCACCAAGAGACTAAACAAGAAAGTGGATCAGGGAAGAAGAAAGCTTCATCAAAGAAACAAAAGACAGAAAATGACTTCGTAGATG
+
?@?DDDB;??FFHBGGEFHGGECAFB3CGECHHHCGHH:DH>?@DBDBGHADGGHIIEHGEGIECGEH?EHC9>=@?>=>A=?CCD:((,,,:8(5<834
@1EI
CTTAGCCGTTCACTCCGCTATTACTATGAGAAAGGAATTATGCAAAAGGTGGCTGGAGAGAGATATGTCTACAAGTTTGTGTGTGATCCAGAAGCCCTTTT
+
?@8DD4A@<8D8AFGF=FF?FH<EGCEB9E99?D@BFFFFIIFDFIIF<F@(..B588@=E5-?CC:?B;;.?)66;@>;=(;;,>;@B@::?:3<<@<>@
@1EJ
TGTTGACCTTGATCGTCAGCTGAAGAAAACTACAGAGGAACTAAATGAAGCTTTGTCAGCAAAGGAAGAAATTGCTCAAAGATGCCATGAACTGGATATGC
+
@@@DDDDDHFHHBHGAFGGEEGHGHIAGGIGGEBG<DF?BB?FGIIIIGIHHBGDFFFHFH=7@FCGGEGEHH??EEFE@DCEDCCCCCACDDDDDCA@CC
@1EK
CCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTAT
+
@8;BDAFF?F>DA@F9BDGCEHHGCDCDHG;FHGIGIEC<FFHI<GHIEEHGGHDFFFCCEAECA;@@A;;?????BB@?BBBA@@CCAACBBBCCCCACC
@1EL
GTTATTAACTGGAGGAGGGAAAGACAGAAAAATAATTCTGTGGGATCATGATCTGAATCCTGAAAGAGAAATAGAGGTTCCTGATCAGTATGGCACAATC
+
CB@FFFFFGHHHHJJEIJJGIJJJJJIJJJJJJJJJJJJJHHIJGIJJJIJJJIJJJJJJJJJJJJJHHGGHFFFFFEEEEEEDCDEDCDFEDDDDDDDD
@1EM
GAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTC
+
??@DBDDFFDH?AGHIHGGGEIIBEHIG@<AHGGDGIGIGAHGHHIGIIG@CEHHGFDF>CEE?BB;?B?28@AACCCCCCDCCCCCCBBCCCCCCBBBBC
@1EN
CTTCATCCTCAGAAGACAGGAATCGAATGAAAACACTTGGTAGACGGGACTCGAGTGATGATTGGGAGATTCCTGATGGGCAGATTACAGTGGGACAA
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJIJJJJIJJIIAFHIJIJIJHHHHFFFFFEEDEEEDDDDBDDDDDDACDDDDDD
@1EO
CATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCT
+
CC@FFFFFHGHDHJJJIIHIIIIJIJJJJJIIIJIJJJJIJJJGIIJIIIJIJIIGJIJJIEIIHGHHGFFFFFFEEEECEDDDDCCCDDCDDDDDDDDDC
@1EP
GGTTGGCAGTGCGGCCAGCCAAAGCTTTCCCCCTCCTCTGATGATTAAACAGGAACCCAGAGATTTTGCATATGACTCAGAAGTGCCTAGCTGCCACTCC
+
BBBBDFFFHHHHHJJJJJIJJJJJJJJJJJJJJJIJEIJJIIJJJJJJJJJJJJJHHHFFFFAEEEEECDEDDEDDDDDDDDD>ACDDDDDDDCDDDDDD
@1EQ
ATACACACACAGCCGGAGGTCATACTGCATCAGAACCATGAAGAAGATAACTGTGTCCAGAGGACCCCCAGGCCATCCGTGGATAATGTGCACCATAACCC
+
@@@FFFFDHAFHDHCF:EF?BEGEHCFHA>@GHHIIIIIGIEHIICHEHI9@@7=DCGI@CEHEFDECCBB@B?B:CB;58>?@DCCC:>CCAC@>>CC>2
@1ER
CTAAGGGTCAGCGAGGACACCTGCCCACTGAATGTTCATTCTTATGACCCCCAAGGAGAAGGCAGGGTGGATCCTGATCTGTCCAAGCCTAAAAACCTTGC
+
BCCFFBDEHHFHHJJIJJIJJJHIJIIIJIJJJJIJJGIIIJJJIIJGIIJJJJJJ@EHEHHFFEDD>@BDDDDDDDDDECACDDDDDDDDDDDDBBDDDB
@1ES
GCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCC
+
CC@DFFFFHHHGHJIGHIGHIIJIJJJJIJJJJJJJJJJJIIIJJIJJJJJJIJCGGIIJGIJJJJHHHHFFEFFDDCEDDDDDDDDDBADDBCDCDDEEE
@1ET
CATTTGTGACAGCATCTAATGTGAAGACCATTCTGCCCTCTAAGGCTGTTGGTGTCAGCCAGGAGGGGCCTCCAGGCCTTCCGCCTCAGCCTCCACCACC
+
=??AB4BDDCDFDIEHGECFHB@ABD4;ECDC@FEGC)C)CF<CDBB@3?<;0?FGGDG3==A@CBH-9<?A23>@B7A@@C=?@@'53:C9(29<((+8
@1EU
TCTAGAGCTTGCCTTCAGTGGGTTTCGGATTGATCAAACGGAGAACTGCCCTTGGCCTCTATCCCGGAGAATAACGGAGAAATGGCAACATCATGCTGAGT
+
-((((2):;)@())))2)@))(((()(((1(2).))).)((0-/()).))77)<17).().)).)9=3,/,((7(,'(,'((+++69/6((((((+((+((
@1EV
GGGAAGGACGTCCTATGTACCAACGCCAGATGTCTGAGCCAAACATCCCCTTCCCACCACAAGGCTTTAAGCAGGAGTACCACGACCCAGTGTATGAACAC
+
@C@DDDDFGGFDHIGIIEEH>HHG?A?GDHIGIE?9BGHEGGHG@BFGGJJJJIJCHH?HFF9?DCEEECECCDDDBCCD<C><39>BA?(:+>>ACDDDD
@1EW
CACGCGTGATCCAGCTGATGCCCAGCCCCATCATGCACCCTCTGATCCTGAACCCCCGGCACTCCGTGGATTTCAAACAGTCCAGGCTCTCCGAGGACGGG
+
CCCFFFDDHHHHHJIFEHJJJJJJJJJJJJJJJJJJJIJIIJJIIJJJJJJJJJJJHHFDDDDDDDBBDDDDDDEDDDBDACDCDDDDDDDDBDDDDDBDD
@1EX
GGAGTACTCAGGAAAACACGACATGTGAAGATCCTACTCTTCATGGGCTATTCCACAAAGCCACAACTGGCTATTGTTACCCAGTGGGGTGAGGGCTCC
+
=@8:4==BBADDFIEIFEGIE>F<B:?EC*?FBDEF**:?<9?DB@F8BDF<<=FAFDDFDF)=@=??CE?;@>?BA>.6.;>55;?22'828?@.2<<
@1EY
CAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGAC
+
CCCFFFFFHHHHHJJJJJIJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJIJJJJJJJIJJJJJJJJHHHHHFFFDDDDDDDDDEDDDDDDDDDDDDD
@1EZ
GGAATTTTTGGGAAATATGAAAAGCCAAAATTTGTGCAGTGTTTAGCATTCTTGGGGAATGGAGATGTTCTTACTGGAGACTCAGGTGGAGTCATGCTTAT
+
@@@DFFFFDHFA=EGBEHFHFH@FDGIIIEHEGI<?GBD:BDFGIIGGEGIIIIIIFCBCCEHGECHGE?EFEEEEC9;BAEEDED;@B?BCCDADCDDDA
@1F0
TAATTTAGGCATTCACTATAAACAGCAGATAGATGGTTTACAGAATGAAATGAGTCAAAAGATAGAAACCATGCAGTTTGAAAAGGACAATTTGATAACT
+
CCCFFFFFHHHHHJJJJIJJJJJJIJJJJGHGHIGJGHGGGHGIIJIJJIJJIFB<FGIIIJJJJJJJGGIGHJJIIIHHGHHHFFFFEACECEEDEDDD
@1F1
TGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTAC
+
@<?BDDDFHAHAFGGIGIIIIIIIIGIIIEBGIIIIIIE?FGHGIID=BFHGIGHGHFIIGHHHHEFEEDCCBCC>CDCCC;?@@BD?BBDDD?>CCDDC
@1F2
CCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJHHJJJJJJJHHIIJJJJGIJJJJJIJJJHHHFFEFFDEDDDDDDDCEEDDDDDDDDDDDDDDDDDDD
@1F3
CAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATAT
+
CCCFFFFFFHHHHJJJJEHIJIJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJHIJJJJJJJIJHHHHFFFFFFEEEEDDDDDDDDDDDDDD@CDDEED
@1F4
CAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCT
+
<??DDDDDFHFDHHBHIH?@DCGG?DHCEIIIIGHIGIIBHIGEHGGIGHHFF<CEBBD;@CCCCBCBBBBB8?BC@@CCBBCBBBBBAC@A>CCCCABC
@1F5
CAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGC
+
CCCFFDDFHFDFHHGGDDFAEHGGIDAAEFCHI<3<DGEHHEGG;G@A@FADEHBFEHGIJIB@2(67AEF<EB>?DB>666;;@CB;;=BBBB<B<@:A:
@1F6
CCCGCCCCTCTAAGCCCGGAGCCCGGCGCTTTCCCCGCAAGATGGACGGTTTCGCCGGCAGTCTCGATGATAGTATTTCTGCTGCAAGTACTTCTGATGTT
+
@@CADFDFGHHHHIIIIEG8GGHDHGIIGHGDEHHHDEDAB?CCDDCDD;BBDBDBBBDBDDCCCCCCDDDCC>BDDE>>ACDDCCCDDCCA>ACCEEC>A
@1F7
GCCAACCAAGCCCTCGAGCAGTTATTCCCATGTCCTGTATAACCAATGGAAGTGGTGCAAACAGAAAACCAAGTCATACCAGTGCTGTCTCAATTGCAGG
+
CCCFFFFFHHHHGJJJIGJJJJJJJJJJJJJJJJJJIJIJIJJJJJJJJHIIFFHFHGGIJJJJJHHHHHFFFFDEEFEDEDDDDEDCDDDEDDEDCDDD
@1F8
CGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCA
+
B@BFFDFFFHHHHJJJJJJJJJJJJJIJJJJIGJJJJJJJIJJJJJJJJJJIJJJHHHHHFDDDDDDDDDDDDDDBCCDDDDDDDDDDDDDDDDDDDDD
@1F9
GGGGAATGGAGATGTTCTTACTGGAGACTCAGGTGGAGTCATGCTTATATGGAGCAAAACTACTGTAGAGCCCACACCTGGGAAAGGACCTAAAGGTGTAT
+
@CCFFFFFHGHHHJJJJJJJJJJJJIIJJJJJJEHIHIFHIJJJJJJIJIJIGIJJJJJJJJJJJIIIJJJJJHHHFFFFEDEEDDDDDDDCDDDD,>:@C
@1FA
CTGTGCTAAAGGCGGCTTTGGCTGATGTTTTGAGGCGTCTTGCAATCTCTGAAGATCATGTGGCCTCAGTGAAAAAATCAGTCTCAAGTAAAGGCCAACC
+
@@@DB>DDDB<?DHEHGHHG>GDHI@F9BDHG=DEHH8EA=AEHEHHEDEEBEB;ACCACDCA?AC;:?CCCECC?@BCCC>@>4>A>(:@C>4(8<A?>
@1FB
CCTTGATCGTCAGCTGAAGAAAACTACAGAGGAACTAAATGAAGCTTTGTCAGCAAAGGAAGAAATTGCTCAAAGATGCCATGAACTGGATATGCAGGTTG
+
CCCFFFFFHHHHHJIJJJJJIIJJJJJJJIJJJJJJJIJJJJJJJJIJGIJIJIJJJJIIJIIJJIIJIIJHHHHHHFFFFFCEEEDEDCDDCDDDDD?CD
@1FC
CATTTATATGAGGCAAGAAGGCTTCCTGGCTCATCCCAGCAGAACAGAAGGCTGTATGTTTGAAAAGGGCCCCAGGCAGTTTTATGATGACACCTGTGTTG
+
@<@A=DDBDHFHDEA:AAD@GIIGGBBBCCHHGDBFAHH?F>FEFH9DH9D?DCC=<FGH@CDHFD3;15(,4??ABCC=CCC355:,(;:>35>>:>AA<
@1FD
AAAAAGAAAAGGGTACACTTGAACAAGAAGTTCAAGAATTACAACTTAAAACAGAATTGTTAGAAAAACAGATGAAGGAAAAAGAGAATGATCTTCAAGA
+
CCCFFFFFHHGGF:CGGHIIIDHIGIIIJG?EFHIJJIIIJJIJJJGIJJJGGGGIIIJHGGGIJIIJIGGEHHGGHFFFFEBACCCDDCDDDEDDEDDC
@1FE
CTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCT
+
CCCFFFFFHHHGGJJJJJJJJJJJJJIJJJJJJJIJJEIJJJJGJJHIJJJIJJJJJGHIJIIIIIIHHHHHFFDDDDDDDDEDDEDEDDDDDDDDDDDCD
@1FF
TTAAAACATGAAGCAGAAGTTACAAATTACAAGATAAAACTTGAAATGTTAGAAAAAGAAAAGAATGCTGTGTTAGACAGAATGGCTGAATCACAAGAAGC
+
CCCFFFFFHGFHHJJJIIIIIJJJJIJJHIJIIJJJJIJJJJJJIIJJIIJIJJJIJJIJIJIJJIJJJI@EHIJHHHHHHFFFFFEDEEEDDDDDDDDDD
@1FG
CTCAGCAAGGTACAACTATTCTTCAGTATGCACAGACCTCTGATGGACAGCAGATACTTGTGCCCAGCAATCAGGTGGTCGTACAAACTGCATCAGG
+
CCCFFDDFGHADFIJGHGGIJJGJJIIGIJJJIFHEGHIIIIHIIIIEEIJJIDIIGJIJFHIIIIJJJIJIGHI=CEEFFDEDDEDDDDDDDDCCC
@1FH
CACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCA
+
CCCFFFDFHFHHHJJIJJJJJJJJIJJJJJJJJJJJJJJJJIIJIJJIHHIJIIJGIJJJHHHHHHFFFFFFEEEBCDDDDDCDDDDCDCCDDEDDDDDD
@1FI
GCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCC
+
@CCFFFFDHFHHHDHGBHGIFEHHGEICFGGIGGIEHIGIHGIIFGGHIJAGHGBHIIFGEHFEHFFFFCEECDCEDDCDDBDDDDD>@CACCCDCDD@CD
@1FJ
AAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGG
+
@C@DFFFFHHHHGJJIJJIEHIIJJGJJJJIIJJJJJJJJJJJJJJIIJGGIJJIJGIIJJIHGBHFFFFCEEEFEEEDDDDDBDDDCDDDBDDDDDDDDD
@1FK
CTATGGAGTGTGCGGCGATGGGGACCCCCTCATCATGGTCTTTGAATACATGAAGCATGGAGACCTGAATAAGTTCCTCAGGGCCCATGGGCCAGATGCA
+
;?<DDDD3++<A<)@CE8:@@DD6?DDB@6@ACC;=@===@;7AD9ACDAD@DDAA@A@>>=;>?:9>AA;(:>>>333:9><<>;8><A?<>>?>>:>>
@1FL
CTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGC
+
CCCFFFFFHHHHHJJJJJJJJJJJIJIGIJJJJJJJJIJIJJIJJJJJJJIJJJJJJJJJJJHHFFEEDEEEDDDDDDDDDDCDDDDEDDDCCDDDDDDCD
@1FM
GAAAGACTCAATCAATCTGATTCTATAGAAGACCCTAACAGTCCAGCAGGAAGAAGGCATTTGCAGCTCCAGACTCAATTAGAACAGCTCCAAGAAGAAAC
+
@@@DDDABDFHGGIIIIIIGGIJIIJGFDGIEIIIIJGGIBDHHHHCEGGIGHEGIJIJJGHE;F@AGCGIIG;CA=CDDDDCDACC@CCC@AC9?C?CC:
@1FN
AATAATCACTGCCCAGCGTCCTCCGAGTCCCACCCGAAGCCATCCAGCCCCCGGCAGGAGAGCACACGCGTGATCCAGCTGATGCCCAGCCCCATCATGC
+
8?@DBDDDAADFDBD3EFEDDEHEEF>?FFGFBG?8DF@FFB@FFFEF@@@E4/=;;,(5<B?59<?&5;05?A>A::>@:>(::>?:(8?@BB@<@AAA
@1FO
CTAGAATTAAAACATGAAGCAGAAGTTACAAATTACAAGATAAAACTTGAAATGTTAGAAAAAGAAAAGAATGCTGTGTTAGACAGAATGGCTGAATCAC
+
CCCFFFFFGHHHHIIJJJJJJJIJJHHIHHIIIGGIJJJJIIHIIJJIJIHJIIHHIIIJJIJJJJGEGGGIJJEHAEHHHEFFFFFCCCECDDDDDDDD
@1FP
CGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCG
+
CCCDFFDDFHHHHJJJJGHIHEHGHGGHGIIHJJGIJJIJGFHIIHHHFFFFECBCCCEDDDDDDDDDB@CCDDDDDDDDBDBDDDBDCDDDDEDDCCDDD
@1FQ
CCCAATTGAAAAGAGAAATAAGGTTAATGAAAAACAGAGAAGCTGCTCGAGAGTGTCGCAGAAAGAAGAAAGAATATGTGAAATGCCTGGAAAACCGAGTT
+
CCCFFFFFFHFFGGGGEHIJJJJHJJJJIJJJIJJJIJAFHIJJJJGIIEIHGBE=CEHIEBHHFHEEFFFFEEECEE@BDEDACCCDCBDDDDDDDDD?@
@1FR
AGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJGHIJJJJHHEEHHFFFFEECEEDDDDDDDDDCDDDDDDDDDDD
@1FS
CGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCG
+
@@@DDFFFHGHHHIIIHHHJFGIJJIJGIGIGHIIIIJJIGHIIJHHHFFFFEEDEEEDDDDEDDDDDDDDCDDDBBBDBDDBBDDDDDDCCCDDDCDDDB
@1FT
CGAAGCCATCCAGCCCCCGGCAGGAGAGCACACGCGTGATCCAGCTGATGCCCAGCCCCATCATGCACCCTCTGATCCTGAACCCCCGGCACTCCGTGGAT
+
@@@DDDDD>D?DHGBGGDHGBFHICFDGDFFCEGGGAEEEEBBD@@C@>C>@C;A==?=BC<A>C@CCCBBB?C@CCCCC@CA8550<@593+9<?8?B?@
@1FU
GCTGAATCACAAGAAGCTGAATTAGAGAGGCTGAGAACACAGCTTCTATTTAGTCACGAAGAAGAGCTTTCCAAACTGAAGGAAGATTTAGAAATTGAAC
+
@@@FFBDDAHFD?G?FEGGH@FHGGGCHGGGGIC?FF>BBFFEGI@HGDHIDHF@FGGEBEEGIHH>CHHAEHFF?DE@CACECB=ACCCCCCCCCCC::
@1FV
CTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATG
+
@@@DBDDDFFFHHEIJJJGGHIJGIGII?FFGHJIJIGGDHIGIJFCCCCGGFFEHCEB?C?CEE@CCEDDDDCCCCDD@B:@CDDDBDB79?@@CAABAD
@1FW
CTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGC
+
@@@?DD?D>FF>4<2CGADE?<A:FE;GBGFEFFC@;?8BFFIFC*B/*/BFF>BFF@FGECC@E2?;A;;B?DD@C@BC@65;ABB?9,(,::<5<34:
@1FX
AATATATTTCTTCATGAAGACCTCACAGTAAAAATAGGTGATTTTGGTCTAGCTACAGAGAAATCTCGATGGAGTGGGTCCCATCAGTTTGAACAGTTGTC
+
@@@FFFDFDDFFFJJIJJJJJIIJGIHIGHIGIHGHIJBF?FGHEAHIJGEEHGH>ABFGIJFG:=FEIGGGEC@CEHEEFDCBCCCCB>A@CDDD>CCCC
@1FY
GGACGAAGAGGGCAAAGAGAATGGGTGTTGAAAGGATAATAGGGTAGTTGGTGGAGTGGAGGCCATTGGGAAGGTGCGGGATTTGATGGTTTTAGGAGAA
+
+:;22)02)2+))++++2<<+*111*)1)00***0)**0**0*9))-))))--((.)6(.(,(((.(.(.(-,(-5(''))&(++((((+(((++((++(
@1FZ
CAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCG
+
@@@DFFFDHGHGGGAB>DHGGGHFGIGIIJJJCGHHGGIGEHIECFHIIEGGGFHIIDGGIHI@ADHFFGFFFCEEEEAC@BBDB@?@DD??:@C:@CDDC
@1G0
CTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGT
+
CCCFFFFFHGHHHJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJIJJJJJHHHHGGFFFFDEDDDDDDDDDDDDDDDDDDDDDC
@1G1
CACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCA
+
CCCFFFFFFFGHDGHIIJJJJJJCFEHIFIJJJJJJJJGHIIJJJJIJJIJIJGHGJIGGGHHHHHFFFFFFEEECABCDDBABDDDCCCDEDDDDCCDD
@1G2
GGAACGAGCGGGGGGCGCCCCGTGGGGGCCTGAGGTGTAGGTGCGTGTACTTCGGGACCTCGGGGGGGGAGGCGGGGGGGGGGGGGGGATGGGGGAGGG
+
7((-(:-0(0((-')&)0&&&&&)0&)&&)(+((+(2(((3((()())+(5(((&)&&(((+&0&)&&&&)-+&&&&0&)00-&55&)&&(+(()&)&)
@1G3
TGGTGATGTGGCAGTGAAAATGTTGAATGTGACAGCACCTACACCTCAGCAGTTACAAGCCTTCAAAAAATGAAGTAGGAGTACTCAGGAAAACACGACAT
+
B@@DDDFFDFHFFIGHIJIJJJHIIIIJIHIIIIGHGGIGIGIJIJJJJJJJJIJIIJIJJJJIJJJJJHFHHHF@DEDFE@CEEEDDDDDDDDDDDDDBD
@1G4
GGCAGCTCAGCTTGGACATCAACAAGCTCCCCGGCGAGAAGCTGGGCCGCGTGGTGCACATCATCCAGTCACGGGAGCCCTCCCTGAAGAATTCCAACCCC
+
?;<?D?:B<DFDDGE3A<FGBHIAC?FA?F@GB60@7;F@@))7C;C=D<9,,3,853>3@>:3>:4+(++:099-59?<(<BB34344@9(+>A>:AB9)
@1G5
GGGAGACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTT
+
?@@;B@DFDFHFFIIECBEGHDD?DGGHGFHIIEECHGIGIA>EGHFFFFFCC>@BC@CCFECCCCC>@ACACABCCC93>@&99B<?B9@BBC:@4>AD>
@1G6
GCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGC
+
@C@FFFFFHFDHFGHGEHGHHIIIJIEGIIIGIGGIJGIGIIJJJGJJGIAHIGIGIJGHGFEFFDDEDEBDDDDDDCCCCCCDCCDDDDCCDDDDDD@C
@1G7
GGCTTCTCGTCCTCAGAGTCGGAGAGCTCCAGTGAGTCCAGCTCCTCTGACAGCGAAGACTCCGAAACAGGTCCTGCCTAATCATTGGACACGGACTCTT
+
B@@FFFFFHHHHGJJJJJHGIGEGHIIIGIGI?DGIGIJIJIJJJJIJJJJIIIJJIHGHFFFFDDDDDDBACDDDDDDDDDDDDEDCCCCBDDDBDDDD
@1G8
ACTCGATCCGCCTGCCTGCGCACCTGCGCTTGCAGCCAATTTACTGGAGCAGGGATGACGTAGCCCAGTGGCTCAAGTGGGCTGAAAATGAGTTTTCTTT
+
CCCFFFFFHGHHHJJJJJJJIJJIJJJJJJJJJJJJJJJJJJJJJJJHJJJJHHEFFFFDDDEDDDDDDDDDDDDDDDDDDDDDDDDDDDAC:@CDDDCC
@1G9
CAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGC
+
CCCFFFFFHHHHHJJIJJIEHIJJJIJJJJGGHIJJJJGJJJJJJJJJJIJJJJJJJJJIJJJJIFHHFFFFDEEDEDDDDECDDDDDCDDDDDDDDEDB
@1GA
TGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAAT
+
@@@FDDFFFHHHHBGIIIIDGEGIHJJIIHGGGGIGGIIIIGIGF@?BFHHGGHGGIIGIHHIGJEFFHFFFFDDC>@=CCDDDDDDDDDDDDDCDCCCCC
@1GB
CAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTTATGGGCAGG
+
CCCFFFFFHHHHHJJHIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJGIJJIJJJJHHFFDDDDDDDDDDDCCDDDEDDD>B@BDDDDDDDDDD
@1GC
TCCCCTTCCCACCACAAGGCTTTAAGCAGGAGTACCACGACCCAGTGTATGAACACAACACCATGGTTGGCAGTGCGGCCAGCCAAAGCTTTCCCCCTCCT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJHHIJIJJJJJJJJHIHIJJJJJJJJJJHHHFFFFFFDDEDDCCDDDDDDDDDDDDDDDDDDDDDDDDDD
@1GD
GATTCCTGATGGGCAGATTACAGTGGGACAAAGAATTGGATCTGGATCATTTGGAACAGTCTACAAGGGAAAGTGGCATGGTGATGTGGCAGTGAAAATGT
+
@@BFBBFFHHHGGGJIIJJIIJJHHIJJGJJJIGIIJJIGIIIGHJIIJHJJJEGIDHICFHIJJIIIIIGHG7?CBEFFE;@>A@@CDBDD9@@CDDCC>
@1GE
CCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCT
+
CCCFFFF?FHFHFHGIIGHHGEHIHGGHGHJIIIIIJIIJJJJIFJJBGHHIJIJAHGGHJGIIHDEFHGFFBDD?@CECECDCCDD?CC?C>CBDCBDD
@1GF
GACTGGTCGAGGCATGGAATTTAAACTGATTGAGCCTGAAGAGGTGGCCCGACGTTGGGGCATTCAGAAAAACAGGCCAGCTATGAACTATGATAAACTT
+
;8?D?BD?0@CADGF@A@FEFF>>99?*C>DFFC3;0?F>BEF@B;;;C(5@;A>=;69/'9?A@53:@B<?/55+88(2<@:>@BE<:>:>@>B:>(4>
@1GG
CAGGGACCAGATAATTTTTATGGTGGGACGAGGATACCTGTCTCCAGATCTCAGTAAGGTACGGAGTAACTGTCCAAAAGCCATGAAGAGATTAATGGC
+
;;<AABDA<AACFGGIBFHIA?+32A)CB@:?0DB<FE@9/98BBF<FFFFAFFI<CEA)7=EBB?5>A@6;@>;@ABB5=BB::@A:A?(4>@@AAA2
@1GH
CTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATG
+
CCCFFFFFHHHHGJJIJJJJJIJJJJJJJJJJJGIIJJJIJIJIJJJJIJHHGHFFFFFEEEEEDCEDDDDDDDDDBDBBDDDDDEDDDDDDDDDDDDDDD
@1GI
AGAGACAGGAGGATCCAAAGTGGGAATTCCCTCGGAAGAACTTGGTTCTTGGAAAAACTCTAGGAGAAGGCGAATTTGGAAAAGTGGTCAAGGCAACGGCC
+
@@@DDDDDDFFFFG:AACHF?CBCGGEE9E?FBGFII>EFFFFIIIIIIIIIFFIDFECEFIEFEEFD9B;<@B>BBBB@ABBB,>AB@@BBBBBBB@5>B
@1GJ
GCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGT
+
CCCFFFFFHHGHHJIJDFHGIIIJJGHHJJJIIGIIJJIJIIJJJJJJIGHHIJJJJJJFIHFIJJJIHHFFFDDDEEDDCDDDDDDDDDDDDB>CDDDD>
@1GK
CTGAAGACAGACATGGAACGTCACATCAACGAGGAGGACACAGTGCCTCTTTCTCACTTTGATGAGAGCATGGCCTACATGCCGGAAG
+
@<@DD;DDDHAHHIGDBFGACABFFHEGGIIIDEAFGFHGHGHGGGGCGIIIIG;=7=DDDDEAAECEFFBDDAC@>CCC<@CBBBBB
@1GL
CAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGG
+
@CCFFFFFHHHHHIJIJJJJGHJJJJJJJJJJFIIJJJJJJJIJJJJJJJJIJJJJJIIJJJHHHHFFFFFCEEEEEDDDDDDDDDDDDDDCDDDDDDDDD
@1GM
CTTCAAGAAAAATTTGCACAACTTGAAGCAGAGAATAGCATTCTTAAAGATGAAAAGAAAACCCTTGAAGACATGTTGAAAATACATACTCCTGTTAGCC
+
@@@DFFFFHHGDHJJIJFGHGIJHIIGHGIJEHIGGGIJIJJIIIGIJJGIIIGIJIIIIGIIJJJIGGIFGHGCEFHDEFFFDECCEECCCDDDDDDDD
@1GN
GTGGAAGAGAATAAAAAAAGCAAAGCCAAGGAACCTCCTCCTAAAAAGACGAAGAAAAATAATAGCAGCAACAGCAATGTGAGCAAGAAGGAGCCAGCGCC
+
B@@FFFFFHHHHHIJJJJJIIJJIJJIJIJJJIJJHHIGGGIJJJJJIIJIIHEHFFEFEEEEECEDDDDDDDBDDDDD:ACDDDDDDDDBDDDDDDDDDD
@1GO
CTTCTTATGACTCAGTCAGAAGAGGAGCTTGGGGCAATAACATGAATTCTGGCCTCAACAAAAGTCCTCCCCTTGGAGGGGCACAAACGATCAGTAAGAAT
+
@?@D?>DDHFFAH@:CDE>IHEHE;B;A8A:1)?GGBFHCDGHIIG@F??F?BFHGIGCEHHG@=CEHCEEBDEE96>BBBBB?CB??<BBBBCC>::>@C
@1GP
GGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGACTGC
+
@B@FFFFFFGHGHJGJJJJJHFHJJJJJJJJIJIJJJJJJIJJIJIJJJIJJIJIJJJJDHIHHHHGGHFFFFDEEEEDDDDDDDDDBBB@BBDDDDDDDD
@1GQ
CTCAAAGCCGTGCACGAGCAGCTTGCAGCCCTCTCTCAGCCCCAGCAGAACAAACCAAAGAAAAAGGAGAAAGACAAGAAGGAAAAGAAAAAAGAAAAGC
+
CCCFFFFFHHFHHJJJJJJIJJJJJJJJGIJJJJJJJIJJJJJJIJJJJJIJJJGHHHFFFFFEEDDBDDDDDCCDDBCDDDDDDDDBDDDDDDDDDDDD
@1GR
TCCTCATCAGCTCCCAATGTGCATATAAACACAATAGAACCTGTCAATATTGATGACTTGATTAGAGACCAAGGATTTCGTGGTGATGGAGGATCAACCAC
+
@@@FFFFFHHGAFIJIJIJIIJIJIHIHJGHEIJAHGHIIIEIFHGIIIGHIJJJIIGHIEGGIGJJIJIJJIJGGIHFFHEF?BCECCEDDDDDDDCDDB
@1GS
ATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATG
+
CCCFFFFFHFHHGJIJJJIJIJJJJJJIJJJJJJJIJJIJJJJJJJJJIJJJJJGHJJJIIJJHFAEHGHFFFFFFDEDDDDDDDDDDDDDDDDDDDDDDD
@1GT
TATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTC
+
@C@DDDDFGHHHHIGGJJJGEHIIGJIGHIJIJJIDIHGEIJIIEHEGDIIIGIICCEGGGGGGEIEFBDDDDCBCDDCC>AC@DDBCB>@:ACDCC<:>
@1GU
CTCGAGAATGTCGCAGAAAGAAGAAAGAATATGTGAAATGCCTGGAAAACCGAGTTGCAGTCCTGGAAAATCAAAATAAAACTCTAATAGAAGAGTTAAA
+
CCCFFFFFGHFHGIJJJJIJIJIIJJJGIJIJJGIJJJJJJIJJIJJJJIIIIIHIIJIJGHHFHHHFFFFFEEEEEEDDDDDDDDDECDDDDDDDDDED
@1GV
GTCAACAAAGCAGCTATGGGCAGCAGCCTCCCCCTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGC
+
==?DD;:BD>DD8@AE<E<EC33A8CEE?EED):?BD?D@DCD?D6@D(;=AA@3)==AD;3?);;?@2=>6@>>A>>AABAA>:3>:==59>>A:(2<>?
@1GW
CTCCTGTTAGCCAAGAAGAAAGATTGATTTTCTTAGACTCCATTAAGTCCAAATCCAAAGACTCTGTGTGGGAAAAAGAAATAGAAATACTTATAGAGGA
+
CCCFFFFFHHHHHJJIJJIJIJIJIIJIJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJIJJJJJJJHGHGIIIJIHHHFFFFFCEEEDEEDDEDDDDDDD
@1GX
CAATCATTGAAGAATTAAACACAAAAATAATAGAAGAAGAAAAGAAAACTCTTGAGCTAAAGGATAAATTAACAACTGCTGATAAATTACTAGGAGAATT
+
@@<DFADDDDDFBHGHHI?IIGCEGGGF<EH@G9CDGICCFEEHDEG>?BAFHEEFGHGIIGGG@GHBGEHECHCEEAACBDDDFEEDD;>ACCCD@BDD
@1GY
GAAAAGTAGTTTGTTGGCAGAGAATCAGGTATTAATGGAAAGACTCAATCAATCTGATTCTATAGAAGACCCTAACAGTCCAGCAGGAAGAAGGCATTTGC
+
???DDD:A<,A?DCEA>EFI::A;+AFFE+:B<EDFCE@DEIEDCEE@?BDCCEIIDCADBD>=B8B))=@6==ACAC7)=A;);@>7@>?A;=;;A>AA(
@1GZ
CTGGACAACATGATCCGCCGCCTCTCCCCGGCTGAGAGAGCTCAGGGACCCAGGCCGCACCAGGAGAACAACCACCAGGAGTCCTACCCTCTGTCAGTGTC
+
CCCFFFFFHHH?FIIIJJJJJJJJJJJJJJJJJJJJJJIJJJJJJHHHHFFFDDDDDDDDDDDDDDBDDDDDDDDDDDDDDCDDDDDDDDDDDDDDDCCDD
@1H0
CTTTCCTTTTGTGCTTTTCTTTTTTCTTTTCCACTTCCTCTTTCCTTTTGTGCTTTTCTTTTTTCTTTTCCTTCTTGTCTTTCTCCTTTTTCTTTGGTTTG
+
????4+:B<:CAC4A::A,A?FCF6C<+@?19C9C4?*C*0?D:4?<<DA)/9DEA<?)=CDB;@=AD=@CD3A=A3?377?(6>(;>AAAAAAA::(9?1
@1H1
GCTCAGTGTAGCATTAAGCAGGAACGAATTTCATATACACCTCCAGAGAGCCCAGTGCCGAGTTACGCTTCCTCGACGCCACTTCATGTTCCAGTGCCTCG
+
@@@DDDADFDHF>GHGIGIIIIHHI@:EEC<G4CE?FDDHGAFH;?D?GGFDF8=F3CDF;BHEHHHE;;>ACC8?9;??@BC>C@CA>:AA::@@CCCC9
@1H2
CGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCG
+
CCCFFFFFHHHHHJJJJJJJJJJIJJJJJJJJJJIHHJJIJJJIJHHHFFFFEEFEEEEDDDEDDDDDDDDDDDDDDDDDDDDDDDDCDDCDDEDDDDDD@
@1H3
TGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTT
+
CCCFFFFFHHHGHJJJJIIIJJJJJJJJIJJJIJJJJJIJJIJJJJIJJJJIJIJJJIJIHIJJGJJHHHHHFFFFFFEEEDDDDDDDDBDDDDDDDDCCD
@1H4
ATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGG
+
@CCDFFFFHGHHHJIJJJJJJJIDFHIGIJJGHJJJIJJJJJJJJJJGJHHHHFFFFFEEEEEEECDDDDDDDDDDDDDDCDDEDDDDDDDDDDDDDDDD
@1H5
CACAGACCACCCAGGCATATGGGCAACAAAGCTGTGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGC
+
CCCFFFFFHHHHHJIJJJJJJJJIJJJJJIJJJGHIJJJJJJJJJJGJJIJJJGIJJJJJIJIGHHHHHFFFFFDDEEDDDDDCDDDDDDDDDDDDDDD
@1H6
GGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTAC
+
@@@DDBABFB:DF9EFEEDEEEHHHIFDFIFFEF<FFFIEIFFFFDFFIFFIIIIFEF?EDBD><>9>A>=BBB?B@:5>>B>@@BDEBB(:<??BBBBAB
@1H7
GTCAGATGTATATGCATTTGGAATTGTTCTGTATGAATTGATGACTGGACAGTTACCTTATTCAAACATCAACAACAGGGACCAGATAATTTTTATGGTGG
+
@@@FFDEFFHFFHGIIGGIJJIGHIGHHIGHFHIIIFIIJIIEHIGIGIIIIJGHIGGHJIIEIHIEIHGGIGIIGEHGIHEHEFFFFFCEEEDCEDD>@?
@1H8
CAAGGGTTAGAAAAGCAAGTCCTGGGATTGCAGAAAGGACAACAAAAAGGGGGTCGTGGAGTGCTTCCTCAAGGGAAGGAGACTTTAGCAGTGCACTGGG
+
=>+=1+AA=+<?BACA7A7?ACCA+?7AB=****11?)0)00580=(0.-7<<->9399;;5;5-;55((5=?9(;;;<7;(+8:?=?8;(+8;(88;=;
@1H9
GGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACAC
+
CCCFFFFFHHGHHJJJJHJJJJJJJJJJHIJJJJJJIJJJJJJJJIJJJJIJJJJHIGJIIJIJJJIJHHHHHFFFFFDDEEDDDDDDDDDEEDDDDDDD
@1HA
GGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCT
+
@CCDFFFDHHHHGJIIJJJIIIJJJJJJIJJJIIJJJJJJIJJIIIGIJJJIJJJJFIIIIIJHHHGEHHFFFFDFEDEECDADDDCDDDDDDDDCDDDD
@1HB
CAGTGCTGTCTCAATTGCAGGAAAAGAAACTCTTTCATCTGCTGCTAAAAGTGGTACAGAAAAAAAGAAAGAAAAACCACAAGGACAGAGAGAAAAAAA
+
@@@BDDEFHHGDHDGEHBBG;ACGECHIIIFGGIIIGHHIIBHGGFGIGII??D0?<DHHDBFDHBEEHFFFDEFECBB@BBA?<<C@?A<8?ACDDBB
@1HC
AGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCT
+
CCCFFFFFFHGHHIJIIIIJJGHIJGJJJJIIIIGGGEHFHIGBGHGIIIIIJJGIIGGGHIHGGJJIEHHHEHFFFFFCDEEBCADCCCDDDDDDDDEED
@1HD
TGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTAT
+
@@@FDEFFHFHHFHHGIJJJJGHGGGEFIIJGGJJJJIIGGIJJIIIJIJGEIIEGFHHGFFFFFEDDCCCCDDCACCDDCB?BB?BBCDDDBCECDDDC
@1HE
GTCACATCAACGAGGAGGACACAGTGCCTCTTTCTCACTTTGATGAGAGCATGGCCTACATGCCGGAAGGGGGCTGCTGCAACCCCCACCCCTACAACGA
+
;:?B;DDBFFFD?C@@A@FC;AC9?::?C@FDDFFCFFFFEF<B@F?FDFC@DDFDGFIIAEEEDE?DBBC>;8?;<>>A9A48@@>05<B9?B?A>@@<
@1HF
CTAAACTTAGCCTCTCACCAAGGGAGCATCCCCTCAGTCCTCACCATGCCTCAGGAGGCCAGGGCAGCCAGAGAGCATCCCACCTGCTCCCTGCTGGAGC
+
?@;=:BD?F::3<C3::E@@?31A?EGE99C:C;:?D:?*0*00)9?B9BFFFFC<5-(-.6=8;A61?;62.=?(5>>B9@@B<A9@:>?9A8@3:?<(
@1HG
CAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCC
+
?@@FFFFFDHGHGJJFGHIIIGGIIIJIIJIGIGFIJJJJJIJGIIGGGHIJICGEGAEHGHGCEH3?DDFCEEDDDD?;?CBDDDDDDCACDCDDDBDD
@1HH
GTGCTTCCTCAAGGGAAGGAGCCTTTAGCAGTGCCCTGGGAAGGCTCTTCAGGAGCCATGTGGGGAGATGACAGAGGTACCCCCATGGCTCAGAGTTATG
+
8:=ADBDBF><:<AF?FHB3<<<ACBDCFHIIIG@C???;D?81?FHBH?F@=FAFHAFD.=CAH15,>;;;@>555(5:>@B?8CCC?<>:?4:+4:A>
@1HI
CACAGTGCCTCTTTCTCACTTTGATGAGAGCATGGCCTACATGCCGGAAGGGGGCTGCTGCAACCCCCACCCCTACAACGAAGGCTACGTGTATTAACAC
+
@?<DDBDDDFFDDIIIII9FHGEHIIIGGGCH<@FCH@GHCHIIIIGGGBHEGEHFBEDEDCA@CBBB8@BB@?B<CCC<<<@5?CACB2<9ADCBD>:>
@1HJ
ACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGT
+
CCCFFFFFHHGHGGGJIJJJJJJJJJHHIJJIIJJIIGGJJJGJJJJIJIJJIJJJJJIJJJHFH?EFDFFFFDCDBDDDDDDBDDD@BCDDDDEDDD>@>
@1HK
GGACTTCAGACATTAACCATGACAAATTCAGGCAGTACTCAGCAAGGTACAACTATTCTTCAGTATGCACAGACCTCTGATGGACAGCAGATACTTGTGCC
+
@@CDFFFDHHHDFGIIIJJIGGIIIJIJCGHIIGGEHGGGHIHIIJJFEFGIJIIJJJJIIJJGEGFHGGHCAHIGHCEHEEE@DFFF@BCCCDCDCCDDD
@1HL
CTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTAT
+
@@@DDDDDFFAAFG:F+:CDDGBA<FGAGCFEFDEFEFFFF0@=7C;CE;DF.777=@?;;BB;;AABBBB:5>A>BB>ABB@:98??B5+88+2:@8(>:
@1HM
ATTAATGGCAGAGTGCCTCAAAAAGAAAAGAGATGAGAGACCACTCTTTCCCCAAATTCTCGCCTCTATTGAGCTGCTGGCCCGCTCATTGCCAAAAATTC
+
CC@FFFFFGHHHFFHHIJJJJJIIJIJJJIGJHJIJJGGJJIJJIIIJJJIJJJJIIIJJIIIJHHHHHFFFEFFEEDEEDDDDDDDDCDDCDDDDDDDDD
@1HN
AGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACT
+
@@@FDFFDHDHD?DDEGECGFFHEGBGBGGIGIIJIIGEHBFHEFACHE==FGIIJJ>AEHAEHHHHDFFCCE>A=ADBBCBBDDDEEDCCD@BDDBBDDD
@1HO
CTGAGCTTTCCCAGCTCACCTCCCTTCTTCTCAATCTATACCCGATCACAGCTACCCCCTCTACCACCGTTTTCGCCCCCAGCTTTCAGATCCCTGTAACT
+
5(;(-))).=?8)9(.<>)38(<(2)))2)):6).3)).>;))(-5(().9(3:3;=?'''))36:),,(,.,(33;3'3,,34:6(((4(((+2((+2(4
@1HP
GTTGAAAATACATACTCCTGTTAGCCAAGAAGAAAGATTGATTTTCTTAGACTCCATTAAGTCCAAATCCAAAGACTCTGTGTGGGAAAAAGAAATAGAA
+
@@@FFFFFHHHGHJJIGGIIHHIEGIGHIIJEHGBFHIIIGIGGJJJIJJIFII@GIJJJJBFHIJIJJIJJIJGHGIHF?E=ABFFEDDEBBDCDDDDC
@1HQ
CAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCAC
+
:=1+=?DD=D8,2C4EEEABFB<:CFEB2CE381:)?D<:6?@99D=8B8===@2AD;A.)=;;AD>=.?;A;;;;6;(;25(;>A<5=;<??????<?9<
@1HR
GGCAAAGCCAAGCTTGCCCAGTTTCGACAAAGAAAAGCTCAGTCGGATGGGCAGAGTCCTTCCAAGAAGCAGAAAAAAAAGAGAAAAACGTCAAGCAGAA
+
@@@BDD3DDHFA;GGEFDCFHCBHG7F;FGECHAHI<D@AB9BDAF>(<;CA34;;.=?CHAECDEDC96;;A?AC<8?>389?CCCB@0+885>ABC(9
@1HS
GCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGT
+
@@@FFFFFHFHHDIIGIIIJJIHIJJIIGIGJIGJHIGGGGHIIJEHBCGEHJIIEGIJGDGHJIIJHHFBBACBDDDCDDDCCCDDDDDD@CCCDDCDCA
@1HT
CTTCAACACCCAAATTAATACCAAAAGTTACCAAAACTGCAGACAAGCATAAAGATGTCATCATCAACCAAGAAGGAGAATATATTAAAATGTTTATGCGC
+
CCCFFFFFGHHHHJJJJJJJJJIJJJJHIIJJIJJIJJJJJJIJGJJJJIJJJIIGIHIIHGGHHIJJIJJFHHHFFFFEEEEEEEEFDDEDDDEDDCCDD
@1HU
CCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTC
+
C@CFFFDFGHHHGJIIJIIIIJIJJIGIJJJJJJGIJIJIIJIIJJJJJJJJJJJIIIIJIIJIIIIEEFHHFFEDDDDDCDDDDCEDEDACDDDDDCDDC
@1HV
ATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGAT
+
@BCDFFFFHHHGHJIJIIJGGGIIFHGIJJJIIGIIIIJJJIJIJJIJIJJJJIIIIIHEHDEFFFFFCCDEDDCCCDDD8=CCCBACCDD@CDDDDDDDD
@1HW
CGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCA
+
@@?DDADDDHHHHIJJGIIGHIIHGFGHIIIJIJIJGIGBGIJJIGIIJJIIIJJHHHHGFDD@BDBBBBDDDDD:>ADDDDDDDDDBDBDBBDDDDDD
@1HX
AAAGGAACTAGAATTAAAACATGAAGCAGAAGTTACAAATTACAAGATAAAACTTGAAATGTTAGAAAAAGAAAAGAATGCTGTGTTAGACAGAATGGCTG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIIJJJJGIIGJJJJJJJJJJHHHHHFFFFFFEEEEEEDDDDDDDDD
@1HY
GTTCATTTATGTGTTATTGATGACTCCAATGAGCATATGCTTACTGTATGGGACTGGCAGAGGAAAGCAAAAGGAGCAGAAATAAAGACAACAAATGAAGT
+
CB@FFFFFHHHFHHIJJJJJJIJJJJJJJJJJJJJJJIJJJJJJJJBFHHHGHHIIJJIIIHIGJJJJJJJJIGEHHHDFFFFFEEEEDDDDDDDDDDCDC
@1HZ
TTTTTATCATCATAACTGCCTGAGTGTTCGTAGTATGAAAGTTAATGACTGGGATGGGGATCAAACGACGATGATGTATGGTAAAGATGAAGATCGTAGG
+
(75(-;.)9)2).9.))))).)9).).))(2)(())))))))27:)9)0))(.()(09==--6)))-'',,(,(((((--(((6(((((,((((72,2(2
@1I0
GAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGAC
+
C@CFFFFFHGHHHJJIJJJJJJJJJJJJJJJJJIGIJJJIJJJJJJJJJJJJHHHHFFFFDEDEDEDDDDDDDDDDDDDDDDDDDDDDDDDDDDDEDDDDD
@1I1
CTTTCTGAACAATTGAAACAGAAACATGGTGAGATTAGTTTTCTAAATGAAGAAGTTAAATCTTTAAAGCAAGAGAAAGAACAAGTTTCATTGAGATGT
+
@@@D=D?;D?>DFHB@EFD?GC@G:A@FHA<A?*?C9C?DHCCADGHBGGEHIBH@HEIGBF@FHB=FFDA>=3@>DE@HHCCDDEDDEC@>>6>ACCD
@1I2
TATAGATATTGCACGACAGACTGCACAGGGCATGGATTACTTACACGCCAAGTCAATCATCCACAGAGACCTCAAGAGTAATAATATATTTCTTCATGA
+
@@@FFFFDFHFAHIEEHIIJJGIFEEGIGHJJIEDFHHDGCHGIIIJJJIJJJIJJGIEEEHHHFHHFECD@CEEEAB(5ACDCCDDDEEDDEDDDEDD
@1I3
GTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCC
+
CCCFFFFFHGHHFHIJJIIJIIJJJJJJJJJJJJJJJJIJJIJJJJIJJJJJJIJJJJJJJJJIJJJHHHHHHFFFFFFFDDEEEDDDDDDDDDDDDDD
@1I4
TGGAGTTTGTCACCAGTGGAGGCCGGATGGACCCACCCAAGAACTGCCCTGGGCCTGTATACCGGATAATGACTCAGTGCTGGCAACATCAGCCTGAAGAC
+
@@@DDDBEFFGHDGHHCFHGHIDGIGCFGGHJEHCGGBEIHIIIJJJIGIBHHEAHA;@BCDDCDDB>@CCCCDDCC5@@CCDBCC@DCCDDDDDDDCCCC
@1I5
CCCTTGGAGGGGCACAAACGATCAGTAAGAATACAGAACAACGGCCCCAGCCAGATCCGTATCAGATCCTGGGCCCGACCAGCAGTCGCCTAGCCAACCCT
+
>;>1772<++?=<=A7C=2?8A3==*0?A7A=*779=*0*/=A0556:;(.;>@5>36=;;,,5-((55=?:((,55;055223;(3&)8&)+8;898092
@1I6
AGAATATATTAAAATGTTTATGCGCGGTCGGCCAATTACCATGTTCATTCCTTCCGATGTTGACAACTATGATGACATCAGAACGGAACTGACTCCTG
+
=?+B=BBD?DDDAEEIBEEFD,AF@F1??@66:@DCDD84BC=/=>8==;;ACCDD8;<DA>)).;?@A>A;AADAAA;35>A?6'8<;AA(::>>>>
@1I7
CTGAGAAACAGCACTCATAGTAGCACAGCTGCAGACTTACTACAAGCCAAACAACAGATCCTCACTCATCAACAGCAGCTTGAAGAACAAGACCACTTATT
+
CCCFFFFFHHGGHJJJJJIIHJJJJDGHGIGJJJIIJJIJIJJIJJJIHHIGIGGHICHHIJJJJJJJJJJHGHHHFFFFEEEDEEDDDDCDDDDBCDDDE
@1I8
AGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACC
+
?;@DDFDD?FDHHEHI?AHGGCHEHIGIIIEGIAHHECHGHEIIIGGGH/AHE=ADFBCFC6>;>@@CCCC@?;;9ABBC??BCCCCC?:4:>CACCCAA?
@1I9
ATTTTAGAAGAAAAGTGTGCTCTACAGAGACAGCTTGAAGACCTTGTTGAAGAATTGAGCTTTTCAAGGGAACAGATTCAGAGAGCTAGACAGACAATAGC
+
?@@FFDFDFHDDFEECEFIGIJJHGHGJIIJIGIGGGDDHGGGIJBGIIGEGEHIIHIHBEHIIIJIGIHIGIGHEHH?D@CDECCCECA@C?>?BDDCC@
@1IA
AGGAGAACAACCACCAGGAGTCCTACCCTCTGTCAGTGTCTCCCATGGAGAATAATCACTGCCCAGCGTCCTCCGAGTCCCACCCGAAGCCATCCAGCCCC
+
@@@FFDDFGBHDDHJGJJIIGGIGEBDGGGCHEGFHDGGGBHGIEFHGHHIIHHIJGIJJGIGGJIGEHHFFFDDDDBDDCCDDDDDDDDDDDDDDDCDDD
@1IB
AAAGAAAAAAAGAAAAGCACAAAAGGAAAGAGGAAGTGGAAGAGAATAAAAAAAGCAAAGCCAAGGAACCTCCTCCTAAAAAGACGAAGAAAAATAATAGC
+
?@<BBDDDFFFFDEGBHFIJJEEIGGIEDFCGH;BB?D@BGEBHHIGGIIGHHE8>>@A@C=ACDDBC?<9<A?ACACCDDCD0?<95<@C9CA8@AADDC
@1IC
CCCAGAGATTTTGCATATGACTCAGAAGTGCCTAGCTGCCACTCCATTTATATGAGGCAAGAAGGCTTCCTGGCTCATCCCAGCAGAACAGAAGGCTGTAT
+
CCCFFFFFGHHDHJJEHIIJHEIJIIIHFHGHJIIGIEHIIJDHGEHJJJJFIHGGIIJIJJIJJGDFGIEHIIFGHEHEFFFFEEDEEDDCDCBDDB<CA
@1ID
GAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCGATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTG
+
@@@DD8DDHDF8?BGGGDHIE@F;FCHGBFGB@GB9DHGF>DH'6.;A8@@GGG<D?=EE@?D;?@C;@C15=B??CBBCB?(5;:@>@CCB>9@B<@BA>
@1IE
GGCTTCCTGGCTCATCCCAGCAGAACAGAAGGCTGTATGTTTGAAAAGGGCCCCAGGCAGTTTTATGATGACACCTGTGTTGTCCCAGAAAAATTCGATGG
+
CCCFFFFFHHGHHJJJJJJJJJJJJJJIJJJJJJJ?FGIHIJJIJGIJJIJJJIJIIIIHHGIHHHHHHHFFFFFED@CEDDDDDDDDDDDDDDDDDEEED
@1IF
ATGATGGTTAAGAGGAGAGACTACTTGGACCTTGCGGCGTCCACTCCATCTGACTCCCTGATTTATGACGACGGCCTCTCAGAGGAGGAGACACCGCTGGT
+
CCCFFFFDFHFHDHIHD@FHIIJJIJIIIIIJJJHJJIDBFHIIIGIJHHHHGBDDDDDECEEEE@CACBDDDBDDDDDDDDA>@??@??BBDDDDDDDDC
@1IG
CAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCT
+
CCCFFFFFHHHHHJJJJJJJJJJJJIIJJJJJJJJJIJJJJJJJJJJJJJJJIIJHHHHHHFFFFFEEEEDEDDDDDDDDDDD>BDDDDDDDDDDDDDDDD
@1IH
GCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCC
+
8??1BDA>3:A1AEE?E3A<CEFFIIBE>CEE3D)087?8B78=B38@)=@=2@9.?3A)?)7..6;@@9>A:;>;;5(,5=(58??00<(:A>>><<<(
@1II
CGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCC
+
CCCFFFFFHHHHHJJJHHIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIIJJJIJJHHHFFFFDDEEEEDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDD
@1IJ
CCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATGACATCTCCTGTGACTCTCACCTCTCAGACAACTAAGACAGATGACCCCCAATTGAAAAGAGAAAT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJIIIGHJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJIJJJJIIJJHHHHHFFFFDDDDDDCDDDDDDCDDD
@1IK
ATTGGAGGCTAAAGATAAGCAATTTAAAGAAAATTTTAAAAGGAATCTTGGATTATAATCATGAGATTTTAGGACAGCAAATTAATGACTTTACCCTTCCT
+
CCCFFFFFHGHHHJJJJJJJJJJJJIJIIIJJJJJJJIJJJJJIIJJJJJJGIIJIJJIJIJJJIGHIJJIIJHGIGHHHFFFFFFFEEEEEEEDDDDDDD
@1IL
TATGTCTACAAGTTTGTGTGTGATCCAGAAGCCCTTTTCTCCATGGCCTTTCCAGATAATCAGCGTCCACTGCTGAAGACAGACATGGAACGTCACATCA
+
C@@FFFFFHDDHFGIIHGGGFFBHGHIIIGDGHIIJFICHIJJIIICGCHJJJIGE@BDHGGEBF;CBGHCHH>EHADFFFFAABEDDCCDBBDB?CDAC
@1IM
GTTCAACATGTTGTCATGACAGCCATTCAAGAGCTGATGAGTAAAGAATCTCCTGTCTCTGCTGGAAATGATGCCTATGTTGACCTTGATCGTCAGCTGA
+
CCCFFFFFHHHHHHIJJJJJJJJJIJJJJJJIJJJJJJJIJHHIJJJJJJJJJJIIJJJIJJJJJIJJJJIJIJJJJJJHGHHHHHDFFFFDEDDDDDDD
@1IN
GGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGG
+
?@@DFADDBFFDFGIGCHIGIIJJJICHIDGIGIJIIJ>FGGGFGHJJBGCGHHEHEHHDEFFFCDDDDDDDDDDBDDDDDDDDDCDCCDDDBDDDDDDDD
@1IO
GTACGGAGTAACTGTCCAAAAGCCATGAAGAGATTAATGGCAGAGTGCCTCAAAAAGAAAAGAGATGAGAGACCACTCTTTCCCCAAGAGAATTTGCAGCC
+
@?8DDA;DFHHD?EHGIGHII@HCCEFCHIDIIIG<BHGGEHII;0?>9D@?FHGGAFEGFG?GDCEHEHEEEEEA>>>CCCCCCC?<<@CCCCCCADCC@
@1IP
TTGAGACCAAATTTGAGATGATCAAACTTATAGATATTGCACGACAGACTGCACAGGGCATGGATTACTTACACGCCAAGTCAATCATCCACAGAGACC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHHHHFFFDDDDDDDDDEDDDDDDDDDDDDDD
@1IQ
ATTAATAAAAATAGTCTGAGGTTTTTATAGTTTGGCTACGTCACGAATCAATTTCTGTCCTCTGAAACAGACTTGGTAGAGCTTGAGTAGCCAGTTGCAT
+
CCCFFFFFHGHHHJGGIGHIJFHGII@HIIIJJGIIJJJJJJJJJIJJJJJIJJCHIGHGGIGIJJJGIIEHEEHH@EFEEECEE>A(>CCDDDACCCDD
@1IR
CAGACATGGAACGTCACATCAACGAGGAGGACACAGTGCCTCTTTCTCACTTTGATGAGAGCATGGCCTACATGCCGGAAGGGGGCTGCTGCAACCCCCAC
+
=?@?=DFDFDFFDFGBFHIJIJIJIGGHGIGIGIJCHJJIJAEBHIE@GGHGGIGGEHIEHGHDHHEEDDEEBCCECB>?BDDDD@>B?A>CACDDDDD>>
@1IS
CAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCC
+
?@@7DDDDAFAFFGIBEHIIIIIHDGD;BFHIIGIFGIEGDGHIII@>D7@GGGHHHHFECDBDCCCC9;;BCCCBBBCCCCCCC?@A@CCCCCCCCCBC
@1IT
TCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAA
+
@@@DD+AADHFDHIIGGFHIGGIIIIG9EDDGIIGIIGGGHHIICHHIIIIIIIHIIHIIEIHHEEECCCCCCCCCCBBCBAB>>>CCECCCCCCCCCB
@1IU
CACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACC
+
@@@FFFFFHHDFHGIJIIIIIGGGIGIIJJIGEGHIIJFIIIIGGDGABGEGIEEGHIHIIJJJJIHHHHHFFFDDDDDDD@CACDCDDDDEDDBDBDDBD
@1IV
AGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCAC
+
@@@;?D?B8C::3CBEEF)@3C@?C@3CF*?*99?4D@4B@3??6?2*?88=<BF@;C>;A=;=2;=?=B?B@C?;65>3-55((5?(((>:>:5(;>1>:
@1IW
CTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCTG
+
:1=D+22AD>DD3+3<C@CFE<E60<CA*?BB?BDC>**09*/(08.8B@@AD7=AD7A).??=);?>A>AAAA;?;/'5((((:+:(4(8<0+92>AA(+
@1IX
AGAAACGCCAGCCCCGGGACTGCAGAAAGGACAACAAACAGGGGGACGGGGGGGGGGTGCTGAAGGGGAGGAGCCGTTAGCAGAGCCCGGGGGAGGCGCGG
+
-07(()28(:5(2=23/(-0(.)7)0)63=>?11=6((((.7;88',9,86&00750&&(+(((5:5&&)0(+((&)&++(+2(((((&08:&&&)+&&&&
@1IY
GTCAGCTCTTGAGTCACGAGTTCAGCAACAAGAAGATGAAATCACTGTGCTAAAGGCGGCTTTGGCTGATGTTTTGAGGCGTCTTGCAATCTCTGA
+
CCCFFFFFHHHHHJJJJJJJHJJJJJJJJJJJJJJIJIJJJJJJJJJIJJJIJJJJJJJHFFFEEEEDDDDDDEDBDDD@DDDDDDDDDDDDDEDD
@1IZ
CACCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATGACATCTCCTTTGACTCTCACCTCTCAGACAACTAAGACAGATGACCCCCAATTGAAAAGAGA
+
;<?BA?DBB8CAAFGDAGI<?:+<F3AACEHG>):<?C@?:900?DB**9B099DBB<?B;F@FGG;FA@;EF@D>?7AC)7@?>?83555@B@>A?8?@
@1J0
CACAAGGACAGAGAGAAAAAAAAAGAGGAATCTCATTCTAATGATCAAAGTCCACAAATTCGAGCATCACCTTCTCCCCAGCCCTCTTCACAACCTCTCC
+
@@@DDDDBHBF?BEED;EHI>F>?:BFCHII<FDHGGCGEGHIIIHIG@C7?CEFHBEEDECACAB>CCCCCCCAACCBCBB@BC?CC>CCCC@B?CCCC
@1J1
CCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCT
+
@@<DD7B?FDFDDDDEGHEHEFCHG>F>1?CCC>@3B?B?9B>FDDB4BC@CBFGH9AAHA@=EHE>EEHH>=DBCDD@BDBD@?ACCD@CCA3>4:9@AC
@1J2
CCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGT
+
@@@DDFDFFFHHGIIIGGEHCFHIGIGHIBHIHGIIIGEIJIGGGGIGIGGGHEEH@EFFCFCCEDECCDCDB>CD>@C@?9<?ACCDBD?CDCDDDDDDC
@1J3
TGAAGCTTTGTCAGCAAAGGAAGAAATTGCTCAAAGATGCCATGAACTGGATATGAAGGTTGCAGCATTGCAGGAAGAGAAAAGGAGTTTGTTGGCAG
+
===A;==<C7<ACB<?+<<+3?++<2?C422?A<@*@?7*??4**0:=0=7=70**997*/78).).8>)))7.=A22.));@9(66.;>?5;;9(,,
@1J4
CCAGGACCTCAGCGAGAAAGGAAGTCATCTTCATCCTCAGAAGACAGGAATCGAATGAAAACACTTGGTAGACGGGACTCGAGTGATGATTGGGAGATTCC
+
@C@BFFBDFHHHGJEHBEHFIIIGIIIGGGCGGIIEIJEIGGD9GDFGIGCHGGFIGHHJJIIHFGGHAHEFFDDC?BACD??,9>3>CFDCDDDBDCDDE
@1J5
CGACCAATCCTCACGATTGAGTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN
+
<<<?<@>??>?@<<>;?@???;###############################################################################
@1J6
CTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTT
+
CCCFFFDDHHHHGJJJJIJJJIJJJJIJJJJJJJIIJJJJJJIJJJJJJJJJJIIIJJGJJIJGFFFFCEEEEDDDDDDDDDDDCCDDDDDDDDDDDDDCC
@1J7
CACTCTTTCCCCAAATTCTCGCCTCTATTGAGCTGCTGGCCCGCTCATTGCCAAAAATTCACCGCAGTGCATCAGAACCCTCCTTGAATCGGGCTGGTTTC
+
@@@AADD?CCFDDIIA?ACF=AG@GCEFA<4EBFGGHIGGEHGI:ABHEHIBHD>CHC;C>EHC>D>;@A>>@>>>>AB;ABBCC<CCA@?@>BBBB?CB@
@1J8
GTCATAGAGAGCTTCCAAGTTGAGAAGTGTGTAACTGAGTATCAGGAAGGCTGCCAGGGACTGGGCTCCAGGGGCAACATTTCCCTGGGTCCTGGAGAAAC
+
::1A:2B4D4<3C<:?CFI:CHHF?H;<CC?8<E?@GE<*111?BF98?F@@GE;?DEF6;(((.=)(-)=CBD635?=@555->559<@<@B:A2+9239
@1J9
GTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGAT
+
CCCFFFFFHGHHFHIJJGHIIGIJIJJJJJJJJJIJJIJJJJJJIICHIIIJJJIJJJGIJJJJHHHHHFFFFFFEEEDEEEDDDBDDDDDDDDCDEEDDE
@1JA
CTAACAAATCACAATTAAGAACCGAACTCAAAAGTATTCATTGACATGGTAACAGAAGAATTTGTGCACGGGAGACTAGGGGAGAAAAAATGAAGAGAAGG
+
0((=(2)(2.;))).)2;)34)(-((1()2)))).)).03)))99))))0)))))73.8=:9)8))63)-'-'',,..-((,3/;7((7&++32+(+3(+8
@1JB
AGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACT
+
???DDDDDC,:<D<<+<AFF>?EFAE;F@4<??;ED?@:?6:B>D4BC@8));CDA=@)=7..==)7.;;;A>?@6@A??AA>AA??<=?=((893>><88
@1JC
GCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGG
+
@;?BD;D;DBFBBDB<EDHEGIIICIIAHH@HCH3C;:A6@FDFCAFH;DH=EEEEH@@?D>CA>>A:>;>;(-;5@A@>A@@C;>>A<9<8:::@(+<8
@1JD
CATTGTGCCCCTGGAAAAAGCTTGGCCAGGGCCACATGGGACAACCGGGGAAGGAGGTCCTGTGGCCACTCTATCCAAGCCTTCCCTAGGTGACCGCTCC
+
@@CFDFFDHHGFDGIGGGHGGEGCHIJJE;ABDGIGIGGHHIIJGJGIGFEFFDBDD;ACDDCCCBBCDCDDDDDDDAABDCCDDCDDDD:@>:ABBDBB
@1JE
CAGCCCCCGGCAGGAGAGCACACGCGTGATCCAGCTGATGCCCAGCCCCATCATGCACCCTCTGATCCTGAACCCCCGGCACTCCGTGGATTTCAAACAGT
+
CCCFFFFFAFHHHDGGIIC@GGAGHHHIIEHIIGIGIIHHHHHHFFFCCCECCCCCCCCBBB<CCDCCCCCCCCCCCCCBBCCCCBBBBBCCCCECCCCCC
@1JF
CCGGCCTTCTCCTGACCCCGAGCAGCGGCCCCTCCGGTCCCCCCTGGACAACATGATCCGCCGCCTCTCCCCGGCTGAGAGAGCTCAGGGACCCAGGCCGC
+
?@<D=@DDB<C?FE4?AEG<?8CGFI<DFBFB27;;-@@BEFD>35=;;:5?59:5;:5+8?77@0;BBBBB>99-0?8:>0+<3@433?88?88(((200
@1JG
TCTCAAACACGGAGGTCATTGAGTGCATTACCCAAGGTCGTGTTTTGGAGCGGCCCCGAGTCTGCCCCAAAGAGGTGTACGATGTCATGCTGGGGTGCTGG
+
@@@DDADDBB?F:FEGBHIIG@D?FFF?FHGIIIIFIDFGGG?FG;B:CHIIIFECCB?85?CCCCBBBBB<?CB+8:ACBBBBBCADCCCCCBB9>@ACC
@1JH
CTGGCTATTGTTACCCAGTGGTGTGAGGGCTCCAGCTTGTATCACCATCTCCATATCATTGAGACCAAATTTGAGATGATCAAACTTATAGATATTGCACG
+
@@@AA?DDDDFADCEAEHACBA:<FHBFGGGBFIGHGGHFGHIGGHGHGGHGIGCFBBCFGGGEHCHGIIFEA>AEHC??;7BC>CCC@C>CDC>CDCCCB
@1JI
CCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATG
+
CCCFFFFFHHHHHJJJJJJJJJJJJIJJJIJFHIJJJIGIJJJJJJJJJIJJJJJIJJIJJJIHHHFFDFDCEEEFEEDDDDDDBDDDDDDDDDCDDDDED
@1JJ
GGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGC
+
CCCFFFFFHHHGHIJJJHIJJJJJJJIJIJHJJJJJJGIJJJJJJJJJJJJJJJJIJHHFFFBCDDDDDDDDDDDDDDDDCCCBDDDDDDDDDDDDDDCDD
@1JK
CAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCC
+
CC@FFDDFHHHHGJIIIJJJJJJJJJJIJIJJJJJIJJFGJJIJJJJJJIJJJJJFIJIJJJJJGHHHHFFFFFDEEEDDDDBDDDDDD@CDDDEDEDDD
@1JL
CAAAGCCTTCGCTAGTCTCCGTATGGCCCGTGCCAACGCCCGGCTCTTCGGCATACGGGCAAAAAGAGCCAAGGAAGCCGCAGAACAGGATGTTGAAA
+
@@CDDEFFHHHHGJIEFGIJJHGECGIJJJHIIIIIJIJJIIIJJHGHGCBFDDEEBBDBDDDDDBDDDDDCB@BDDDDDDBDBCCCCB?CDCCC>CD
@1JM
TGAAATCACTGTGCTAAAGGCGGCTTTGGCTGATGTTTTGAGGCGTCTTGCAATCTCTGAAGATCATGTGGCCTCAGTGAAAAAATCAGTCTCAAGTAA
+
CCCFFFFFGHHHHJJJJJJJJJJJJJJGJGJJGIIIIJJFGGHGIGHHFFFFFFEEEEDDEDDDDDDDDDDDDCBDDACCDDDDDBDDDDCDDEDDCCD
@1JN
GCCCTCCAACCCCCCCACACCATCCAGCACGCCAGTGTCCCCACTGCATCATGCATCTCCAAACTCAACTCATACACCGAAACCTGACCGGGCCTTCCC
+
@@@FFFFDHHHHHJJJFFEGIEGIFIIGHB7@GBHDD=DEIFCHBDFD>DCECEEECCCCDDDBACCD?CCDC:ACDCD@BDBAABCDDDDDDDDCDDD
@1JO
GCAACACGTTTGAAATGAATGGCAAAGCTCTCCTGCTGCTGACCAAAGAGGACTTTCGCTATCGATCTCCTCATTCAGGTGATGTGCTCTATGAACTCCTT
+
?@?DDD?@CF>FBCHBBH<EHEDGEICHB?9?FHIGFGHBDFGGHIIIIEHBBFGAHI>A@@@E9?CE@B@CECC@>A@.;@;;;@A@A>>;@5@@A:>>A
@1JP
ATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCC
+
CCCFFFFFHHHGGHJJJJII@FGHHIGJFGGJJGJGIIJEIJJIGICHIIFHFFHF?CDFFECEEEDDDDDDDDDDDDDDDDDDDDDDDEDDDDDDDDDD
@1JQ
CGGCAGCTCAGCTTGGACATCAACAAGCTCCCCGGCGAGAAGCTGGGCCGCGTGGTGCACATCATCCAGTCACGGGAGCCCTCCCTGAAGAATTCCAACCC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHHFFFDDB=@DABDDDDDDDDDDDDDDDDDDDDDDDDCDDDDDDDCACDDDDEDCDD
@1JR
TGAGACTCCTGCTCAGTGTAGCATTAAGCAGGAACGAATTTCATATACACCTCCAGAGAGCCCAGTGCCGAGTTACGCTTCCTCGACGCCACTTCATGTTC
+
@@@FDFFFFFHHBCGIHIIIEIGIGGIGHIIIFHIGHHIIGIIIIGH@FHIGGHHGHIGGGHIGG@@EEEAD?BCCCABBBC>CBCCCC@BB@CCCD>>@A
@1JS
GGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAAT
+
CCCFFFFFHGHHHJJJJJJJHIIJJJJJGHJIJJIJJJJIJJJJIIJJIJJJJJIJGIJJJJJJJHHHFFFFFEEEEEDDDDDDDDCDBCDDDDDCCEDE
@1JT
GCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTC
+
CCCFFDFFGHHHHIIJJJJJHJJJJJJJJJJJJJJJJJJJJGJJJIIJIJJIJJJJJJJIJJJHHHHHFFFDFDDDDDDDDDEDDDDDDCEDDDDBBDAB
@1JU
GGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTAC
+
@C@BDDDFHDFAHIIIIJJJJJGGGIG@D:DDFFCGHEBBFGEFGDGHEIJGGGHGIJJGGHEEEFFFEEEC@AAACCDDCDDDDBBDDCC?CCCDDDC
@1JV
AGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCAC
+
@@@DBDDDHDFBFHE3C@<@F??;EHAHE:??DCDDDGFA@FH<FEHIEHIDCGHIEH@HHDGAEEAHBD?;;@BCCC;A>5>?CCCCCC:ACA@CDC<?>
@1JW
CAGCTGAAAAGTCACATAATTCTTGGGAAAATTCAGATGATAGCCGTAATAAATTGTCGAAAATACCTTCAACACCCAAATTAATACCAAAAGTTACCAA
+
CC@FFFFFHGHFHIGHJIIIJGIIIJJIIJJJJHIJJJJJJIJIJJJJIIHIJIJIAGHHGGJGJIGJJIHGHHHFFDDEEECEEEDDDDBDD>ACCDDD
@1JX
GGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGT
+
CCCFFFFFHHHHHJJJJJJJJJJIJJJJJJJJJJJJJJIIJJJJJJJFHHIJJJHHHFFFFDEDEDDDDDDDDDDDDDDD>CCCCCDDDEDDEDDDDDDD>
@1JY
CCTGATGCTGCAATGCTGGAAGCAGGAGCCGGACAAAAGGCCGGTGTTTGCGGACATCAGCAAAGACCTGGAGAAGATGATGGTTAAGAGGAGAGACTACT
+
@C@DFFFFHGHHHJJJJIGEHGGGG=DD;GHEGIGICHGIGGGG;@@GHHHHFC?>CCDDDDCCCCCDDDD?B?BCCCCC@@CCD:>A:@?ADBBDC::>C
@1JZ
CTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGC
+
;@<DDFDDFFFD>DFGGHABGEGHEECBEFGE@CDGEB?BFEBFE>@CGICHII@;DD@EHHCEAC=;;?D@?@CEACB9A>55?5?<>>CB@9@552
@1K0
CTTCGGGGTGATCCTCTGGGAGATCTTCACCTATGGAAAGCAGCCATGGTTCCAACTCTCAAACACGGAGGTCATTGAGTGCATTACCCAAGGTCGTGTTT
+
@@<ADDD@01ACDBGGIGGDHIFIGGHEFHII<FG<DDD8??DGCCEHFCG@@CHEGIIIDEEEAEEDCBB5;>AACCC(5>@CC@ACC:??@A><59+83
@1K1
CCACCGCCTACTTCCTGTACCAGCAGCAGGGCCGGCTGGACAAACTGCCAGTCACCTCCCAGAACCTGCAGCTGGAGAACCTGCGCATGAAGCGTCCCA
+
+1=2<08)7ABBCBB9+@<4C><=+1:@@5AA;A4(::=;(.=.67=)7)7);)>>;@@5.;;3;;=9=(9(,5;(,3+(+(28&&09<;8;7&++0)3
@1K2
CCCACAGCTGCAGAGATCTCTGTTCGAGTCCCTAGAGGGCCGGCCGTGGAAGGGGGACACGGGAATATGGCATTCTCTCAGTCCAACCCTCCTTCGGAGTT
+
;?1B;A?3D<8DBE:CBE>@:A3<C8CBA9C9CEBDCBAD7?7'';A<6=CD?<>?/;558'5;58(:33(3((44:+:>A>(4:49>>???<34<?<9<+
@1K3
CAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJIJIJJIIJJJHHHHHFFFFFFEEDEEEDDDDDDDDDDDDDDD@CDDDDDDDDD
@1K4
GAGAATAAAAAAAGCAAAGCCAAGGAACCTCCTCCTAAAAAGACGAAGAAAAATAATAGCAGCAACAGCAATGTGAGCAAGAAGGAGCCAGCGCCCATGA
+
BBBFFFFFHHHHHJJJJJJIJJJJJIIGJJJJJJJJIJJJIJHGIJIJJJIHHGHFFFFFFFEECEDDDDDDDCDECDDDDDDCDDBDDDDBBDDDDDDD
@1K5
CAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGCCACTCAGCCTGCTT
+
====+=0<<<AAA727?+<?>BB7A+??<:@7?==>AAA?A3*AA*=97=A(5(=-6A9;7AB>A>>A9>>)>;>55;5.;;;35(-53(59>?9(55((
@1K6
CTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACC
+
@C@DDEFAHHHFHJJIIGGHGIGGIHGIEHHGIEEGIIGIJIGIIJIHIDGHGGGGGHHFFFFFFCCEEEDCC@ADCCC@DDDDB?>A@A4:ACDDCCCDD
@1K7
TCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACGAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGAC
+
;;8D?BA;DHDDBDBBCCF@HH@D@?F?BCHIGHG<)0)07C;B<CF@FA@=;==@=CEAEAA>DD@@DCAC;;?;;>CCBB?<AAB59>538A>CCC>A
@1K8
CTTCTGGATGACCCTTCAAATTCTCATTTTATTGCCTGGACTGGTCGAGGCATGGAATTTAAACTGATTGAGCCTGAAGAGGTTAGTTTAATAGATTTTA
+
@@@DBBA?FFHFHEE@GBHGHBHHIBBAHHIEH>?:9CCH;GBD:?D@DBHI>BAC:=CGEH@@E@7AE3A>H>D@77;;@=6=3;>C>5::;;@@DCCD
@1K9
CTCTCATCTCTTTTCTTTTTGAGGCACTCTGCCATTAATCTCTTCATGGCTTTTGGACAGTTACTCCGTACCTTACTGAGA
+
??14:DDDDDBDDB>DCEEDFDEDIFEABEEEECCBD?<C<BAA?DCDED>DCEDD3BCCEC@;8=CC.@C5?DD);@D>)
@1KA
CTTTCAGTCAGATGTATATGCATTTGGAATTGTTCTGTATGAATTGATGACTGGACAGTTACCTTATTCAAACATCAACAACAGGGACCAGATAATTTTT
+
CCCFFFFFHHHHHIGHIJJJJJJJJJJJJIIJHIJJIIIIJJJJJJJJJJJJJIJJJJJIJJJJJJJJJJJJJJJIIIIIJIGHGHGFFFEEEEEDDEDD
@1KB
GAACTGTTGCACCGCTCCAGGTCACCTATCACGACAAATCACCGGCCTTCTCCTGACCCCGAGCAGCGGCCCCTCCGGTCCCCCCTGGACAACATGATCCG
+
@@@DFFDDHGFHFHBDAEGGIC<GHIIIG>G@GGIIIC?9BFFDH@GBEGGHGHFEDBDFCB@BBCB@BBBBBBCC@B5>@ABBBB@BB?CBBB<C:ACCB
@1KC
TGAACTGGATATGCAGGTTGCAGCATTGCAGGAAGAGAAAAGTAGTTTGTTGGCAGAGAATCAGGTATTAATGGAAAGACTCAATCAATCTGATTCTAT
+
@@@?BBDDHFFBFDHHGFCGEGIGGIDGGHEEFHI9?C>GHG*?BFF9DB>FCFHE@GGGAAFDG7@E=@D>C77?EE3;B;?CC>C>>5@CCACBAC@
@1KD
AGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAAC
+
BB@DFFFFHHHHHJJJJJJJJJJIJJJJJJJJJJIJJIJJJIJJJJIIIIJJIJJJIJIIJJIJJHHHHHHFFFFFFEEDEEEDDDDDDDDDDDDDDDDDD
@1KE
CTAGATAGCCCCAGAGGGATGCACAGGGATGGGAACACTCTGCCATCCCCCAGCAGCTGGGACCTGCAGCCAGAACTTGCAGCTCCACAGGGAACTCCGGG
+
@@CDDADFHGHHFIFHGHEGGGIJGGGDFEHIIJADHH@BBFGEHIIGIJEHHGHJGJHHEC@DCFDCECABBBDDDCCCDDC9AACCCBDDBBBC>CBDD
@1KF
CTCACCTCTCAGACAACTAAGACAGATGACCCCCAATTGAAAAGAGAAATAAGGTTAATGAAAAACAGAGAAGCTGCTCGAGAGTGTCGCAGAAAGAAGA
+
@@@DDDDDHDFFHHIIGGIJGGJIIGIHGIJIGIJJFIJDHGCHGHGCGGIJIIFHGGIDHGJJIJI=AEHDFEFFDCCD@B2;5>:>B?BD@DDCCBC?
@1KG
CTTAAAGATAATTTAGGCATTCACTATAAACAGCAGATAGATGGTTTACAGAATGAAATGAGTCAAAAGATAGAAACCATGCAGTTTGAAAAGGACAATTT
+
CCCFFFFFHHHHHJJIJJJJJJJJJJIJJJJJJJIJJJJJIJJIIIJJJJEIIIJJJJIJJJGHJJJJJIJIJJIJIIJHHHHHFFFFFFFEEDDDDDDDD
@1KH
CTGACTGCCAATATGAAGGAGGTACCTCTGTTCAGGCTACGTCACTTCCCTTGTGGGAATGTCAATTACGGCTACCAGCAACAGGGCTTGCCCTTAGAAGC
+
@@@FFFFDFHGFHJJJIIGIII<AFHHBHHJICBGFEDFGEFBDHIJEIGIIJDFHJJJIGIJIJIIJGGEHFFFECEDED@BDDB@BBB?CCCCCDDDC?
@1KI
TGGGAAAGGACCTAAAGGTGTATATCAAATCAGCAAACAAATCAAAGCTCATGATGGCAGTGTGTTCACACTTTGTCAGATGAGAAATGGGATGTTATTA
+
@@CFDDFFHFHHHHJGGG<EFFFAHGIIIIABFHEHFFIGIEGGDHHIJIJJIJIHHIJJ=F@CFGIJJJJIGHHEHAE@DFFFFFECEEE?>?>@CCCE
@1KJ
GGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATG
+
@?@FFFFFHHHGHJJIJJJIIGGIIGIIIJJJJJJJJJJIJJIJJJJJJIIJJJJJJHHHGGHFFFFDCDDCDDDCCDCDDDDDDDDCDDDBBBBDDDCDD
@1KK
CAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATAT
+
CCCFFFFFHHHGGIJJJDIIIJJJIJJJJJFJJJJJJJJJIJJJJJJIJJIJJHIIJJJIEIIJHHHHEFFFDFEEEEEDDDDDDDCDDDDDCDEDEEC
@1KL
CCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTTATGGGCAGGAGT
+
+:=<<+<?A<<@CBBBCC4=4A<A>3@;=ABBBAA=A=?7?:==8AAAAA=ABB)=>;>A=A<9=@;25=<:===;=>??9;:2(508;(8:3;((00(+3
@1KM
CACAAAGAAAGTTAGAACAACTCCGGGCAGAGCTGGATGAGATGTATGGGCAGCAGATAGTGCAAATGAAACAAGAATTAATAAGACAACACATGGCAC
+
@CCFFFFEFFHFHIJJJJIIIJJIJIIJJJIJJJJJGIJJJGIJIIIIJJJJJIJIIIIICEEHHHHHFFFFFDEEEEDDDEEDDDDDCDDDDDDDBDD
@1KN
GTTTTTGGTAGCTCTTCTGGATGACCCTTCAAATTCTCATTTTATTGCCTGGACTGGTCGAGGCATGGAATTTAAACTGATTGAGCCTGAAGAGGTGGCCC
+
@?@DFFFFFFHHFEGHGFFBHHJGGIAGIJJJJGGFCGDIGEEGIJBEGHGDCHGGIFEHGHJGEFHGCDDFFFFDC@C>AAC;CCCCDCCDCBD3<@A?B
@1KO
GGGCCTGTCTCCTGCAACCCCTTTGAAACTTGATCCTCTAGGGCCCCTGGCCTCTGAGGTTTGCCAGCAGCCAGTGTACATTCCGAAGAAGGCAGCCTCC
+
@@@BFFFFDFHHHGIEHIGIIJFHIIGGHIJAFCHGHGGEGGDGEGGIGGIIGGHGFGCHIEHHIHHFHBEFFFEC6@CC>BCDDDBDDDA?<<<?BC<A
@1KP
CAGAAAAAAAAAAGAGAAAAACGTCAAGCAGTAAACATGATGTGTCAGCACACCATGATTTGAATATTGATCAATCACAGTGTAATGAAATGTACATAAAT
+
B@@FFFFFGHGHHIDGGIIJJIIGIIJJJJICGHIFHIGGGE=A?EHHHDFDFBDEECDDEDEDDEEFDDEDDDDDDCCD:A:BCDCDDDCC>BCDDEDDC
@1KQ
CAGATAGCTGGCGTGGATAAAGATGGAAGGCCTCTACAACCCCACGTCAGAGTGTGGGATTCTGTTACTCTATCCACACTGCAGATTATTGGACTTGGCAC
+
<;;DBDD><D3BD8CBH?FHCBCCBGG99:C)?DDG<GBGHBBDFE;;@AAEH97=;AE:;?3?BDD@;C3@A;CAC;;;>@CCC>A>C>@CCCCC>C<@:
@1KR
AATTCACTAACAAGAAAACAGGGAATTTTTGGGAAATATGAAAAGCCAAAATTTGTGCAGTGTTTAGCATTCTTGGGGAATGGAGATGTTCTTACTGG
+
@@@DDFFFHHHFHJBGIIJJIIGFEGHIGGGGEIGI>BBDGIEGGBHIGHGIIIG8@FCG=FEGIEGGFHH@EHEFBD5,;@A@B?CA@CACCDDCDD
@1KS
CTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATG
+
@@@DDBBBFFDBHHGIGEGIGHGGCHIG@AFFHGHJIIIJIIFHICHHECGHFEHHHHBECCDCEDEEEDCCDDDCDBCDD>A>CCDDBABBD@@C@B@CC
@1KT
CTTAAAGCACTTAATGAAGAGCTTCATTTGCAAAGAATAAATCCAACTACAGTGAAAATGAAAAGTTCTGTCTTTGATGAAGACAAAACTTTTGTAGC
+
CC@FFFFFHHHHGIJJIJIHIIGIIIIIJIJIIIJGIIJIIIJGIJGJJIJJIEIIJGIJIJJJJGHEIGIIJJII@HHJIHHFHHFFFFFEEC>CEE
@1KU
CACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJIJJJJJJJJIJJJJJJJJJJJJJJJJJJHJHGHHHHFFFFFFEEEEEDDDDDDDDDDDDDDDDDDDDDDDDD
@1KV
GTGTATATCAAATCAGCAAACAAATCAAAGCTCATGATGGCAGTGTGTTCACACTTTGTCAGATGAGAAATGGGATGTTATTAACTGGAGGAGGGAAAGAC
+
@B@DDFFFHHHHHJJJJJJJJJJJIJJJJJJIIIJJHIJJIJI?FFGFHIJJIJJJJJJIJIHGIGHHIJIIJIHHHHHHHHFFFFFFACDABDDBDDDDD
@1KW
GGAAGGACCCACATACCAACGGCGAGGATCACTTCAGCTCTGGCAGTTTTTGGTAGCTCTTCTGGATGACCCTTCAAATTCTCATTTTATTGCCTGGACTG
+
CCCFFFFFGFHHGEIJJGIIEIIGIIIIIJIJJJIJGJJIJJJIIHAEHHFFDDEEECDDDDDDDCCDCDDDCDDDDDDDCCADDDDEDCCDDDDCDDBDD
@1KX
TCACTAACTAACGTGAAAGCCTTACAGAAATCTCCAGGACCTCAGCGAGAAAGGAAGTCATCTTCATCCTCAGAAGACAGGAATCGAATGAAAACACTTGG
+
C@@FFFFFHHHHHFHJJJGIIJJJJJIJIJJJJJJJIIGJJJJIIIJJIJIIJIIJJGIJJJJJGHGHHHHFFFFFCEEEDDDDDDDDDDDDDDDDDDDDD
@1KY
TATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJIJJJJJJJJJHHHHHFFFFEDDEEEEDDDDDDDDDDDDDDDD
@1KZ
CTCACTGCTCCTAGAGCCCTCTTCGCTGACTGCCAATATGAAGGAGGTACCTCTGTTCAGGCTACGTCACTTCCCTTGTGGGAATGTCAATTACGGCTACC
+
@@7BD4AD?BDFFIIIIGE3C?<:CAFF:C143?B?DAF@D>D@B8609BDA=F@FFBFIDFF;EEC>5;7;@DDBDC;@@@2;?B@>>@B@AB8=BB?3?
@1L0
TGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCTAAGTCAATATAGCCAACAGAGCAGC
+
(((-:=>@)81?@<<<<)884(6)8-(1>())1-):39?).)6=)7==2-9=(69))6));)690>?9703=;9(6=797;1(;=(((22;<;0;<<:8;
@1L1
CAGCAACACGTTTGAAATGAATGGCAAAGCTCTCCTGCTGCTGACCAAAGAGGACTTTCGCTATCGATCTCCTCATTCAGGTGATGTGCTCTATGAACTCC
+
?@@DFFDDHFHDHIIIBHEBFHHHIGHFEGGIBFHCGGHDGGIIIGEHGHIIDG@GEHEDHIIGHGHHDFFFF@@CDEA@;5@CCCBCCC>CD@>C@@>>C
@1L2
AAGCTGGGCCGCGTGGTGCACATCATCCAGTCACGGGAGCCCTCCCTGAAGAATTCCAACCCCGACGAGATTGAAATCGACTTTGAGACCCTGAAGCCGTC
+
CCCFFFFFHHHHFHIIIGHIJJJJJJJJJJJIIIJIJJJJIJJHHHFFFFEFDEEEEFEDDDDDBBDDDDDDDDDDDDDDDDDDCCDDDDDDDDDDDDDDD
@1L3
TGAAAACACTTGGTAGACGGGACTCGAGTGATGATTGGGAGATTCCTGATGGGCAGATTACAGTGGGACAAAGAATTGGATCTGGATCATTTGGAACAGTC
+
CC@DADFFHFFHG2<?EBEHI<AFEFGG?CBGEIIIGHBBDHGH@DDG<BFIGB@F;@EHECA=?AA26;?@CEA>ACCA@CC@A:>><@CCDC::>AA:@
@1L4
GTCGCAGAACGAAGAAAGAGTATGTGCAACGCCTGGTAAACCGAGTTGCAGTCCTGGAAAATCAAAATAAAACCCTCATATAAGAGTTAAAAACTTTGA
+
((0-(3(8.)-(9(->>=>)@=3)2=)91)(0<(.<)).)9=(<';=63)).)::1)(.).).6;=>818=3;((7(7(,(5755((7;06(()++2((
@1L5
ATCAGAAGCCACAAGTGGGAATGAGGCCCTCCAACCCCCCCACACCATCCAGCACGCCAGTGTCCCCACTGCATCATGCATCTCCAAACTCAACTCATAC
+
CCCFFFFFHHHHHJJIIIIIJIJIIJIIJJJJJJJJJJJJJIJJHFHHFFFFFDEADDDDDDEEDDDCDDDDDDDDDDCDEDCDDDDDDDDDDDDDDDDD
@1L6
TAGAACAACTCCGGGCAGAGCTGGATGAGATGTATGGGCAGCAGATAGTGCAAATGAAACAAGAATTAATAAGACAACACATGGCACAGATGGAGGAAATG
+
@@@FFFDDHGHFFBGGIIIIGGIIEGHFGHGJ@FHIJJJJIFIIICGG8=DHGIJIEIGIGIGHEHHFFEEFFFCEEDDD;A@ABCDCC:@CCA?B<ACDD
@1L7
TCCGAGGACGGGCTGCATAGGGAAGGGAAGCCCATCAACCTCTCTCATCGGGAAGACCTGGCTTACATGAACCACATCATGGTCTCTGTCTCCCCGCCTG
+
CCCFFFFAFHDDHIHBFHIIGIJFGIJJGGJJJGIJEHIIGJIJIJJIGHGEDFDEEEDCBBDDCDDEDDDC?<BDDDCCCCCDDCDDACCDDDDBDBBB
@1L8
GGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACAC
+
CCCFFFFFFHHHDGIEIIIJIIIGIIIIFFHGJIGIDCEGGIIJJIJIJJJJGHIEFEHGIJGIJJIJHGHHDCFFFDDDEECDDDDDDDDEEDDDDDDD
@1L9
CTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAAGACCAC
+
@@@AD>B?FA?:0C@DEEGEC+94A):??FF@;??BFCGE@@<D9BBFC>B?CF88C1(=3=D72.=?C).,'''98??@<(:,>(,(5@(0&)&(+9<?1
@1LA
GGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTT
+
?@??DDDDFBDDDF>GBAE@GHIIFIGGI?CGCEHDD>DGIEDBFGBG@GHEIIIICCFCHED>EEHFFHHEEEEEEC<;?>=CCE@CC>3>CCCC?A?CC
@1LB
AGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAAC
+
CC@FFFFFHHHHHIJJJIJJJJJJJJJJJJJJJJIIJJJJJJJJJJJJJJJJJJIJJHIGJIJJJHHHHHHFFFFFFEDEEEEDDDDCDDDDDDDDDDDDD
@1LC
GTCACATCAACGAGGAGGACACAGTGCCTCTTTCTCACTTTGATGAGAGCATGGCCTACATGCCGGAAGGGGGCTGCTGCAACCCCCACCCCTACAACGA
+
@@@DFFFFFHFHHJIBGIIIIIGGHIJGHJGJIIIJJGGEIHHIGIJJJJJJJIJJJJJJIJJFIGFEEDDDDDDDDCDCDDD?BDD>BBDDBDBDDDDD
@1LD
TATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTC
+
CCCFFFFFHHGHHJJJJJIJJJJIIJJJJJJJJJJJJJJJJJJJJJJIIJJJJJJJJJJJJIJJJJHHFFFDDDDDDDDDDDDDBDDDDCDDDDEDDDDC
@1LE
TGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAAT
+
CCCFFFFFHHDHFIIIJIJJJIIJJIJJIJJJJJJJDHJJIIJJIJJIIHJIJJJJJIJGJJIJJJHHHFFE@CEEEEDCDDDDDDDDDDCCDCDD>CDCD
@1LF
TGGAAATGGGTGAGGTTGTTGAAAAGGATACAACAGAACTCATGGAAAAACTTGAGGTAACCAAGCGAGAGAAATTAGAGCTGTCACAGAGACTGTCTGAT
+
@@@DDD>DFD<DFEEEEHFHGHEHIECHFFGGHGIIEHGIIDECHIIIIGEGCGGIIIIGEDEGH@EFF>>CCC@CCCCCCCCCC>5@@C3?C@C5::@C3
@1LG
GGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACT
+
@@<BDDBDFHDHHH@;?DHIBEHEFF?EGH@GGF;BD?BFB*9*?D?<FCHHHHIGG==FF;CE5;AA>7?@DECC@CC@CB?ACCCCA
@1LH
GGCTTCTCGTCCTCAGAGTCGGAGAGCTCCAGTGAGTCCAGCTCCTCTGACAGCGAAGACTCCGAAACAGGTCCTGCCTAATCATTGGACACGGACTCTT
+
@@@FFFFFDFHHHGH;FHCHHIBGEF8C@DFGIHIIIGIIIIGIDHCCBDHGAHBGGHHHDDFFCCBBCC?,>>>:CACCCCAAC>CAA@AB<@B<>C@C
@1LI
CATATTTTCTTCTGGACCTGGAGCGGCAATTCACTAACAAGAAAACAGGGAATTTTTGGGAAATATGAAAAGCCAAAATTTGTGCAGTGTTTAGCATTCTT
+
@CC=DDDFHDFHHIDEGHHJEDFHDIGGFGGHIJGHAFGGGHIJFIJGIIJIJJGGIHHH?@=DEDEEEECCB@?CDA5:AD;A@AC(:4:?CDCCCCDDD
@1LJ
GGCATGGATTACTTACACGCCAAGTCAATCATCCACAGAGACCTCAAGAGTAATAATATATTTCTTCATGAAGACCTCACAGTAAAAATAGGTGATTTTGG
+
???DDD>DD3BDDII4<AEECIEFEEC@A<BEEACD@D@DDD@D<DDD<D8*8B<CECDDEIIIIIIIIIIICDDDDD@@DDDDA@AAA3>A;>>ADDAA?
@1LK
CTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTAT
+
??;DDDDBDBFHHFFEHGBDFGEGDBHEEHIIGCHC>CGIAEGBGDF@FHGC@CG;77==CEDHECGHHH;AE;;CC>CCECCCC@AC?<BB;B@@AB>:@
@1LL
GTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGC
+
@CCFFBFFFHDDHIGIIIIG@GEHIHFEHIIGIBFEHIIIIIGDHG@HEGDHHFFFED@B>?@CECEFECEDDDBCBB:@ACDAB??BBBCCDDDDCCC
@1LM
AGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCAC
+
CCCFFFFFHHHHHIIJIJHHHDFHIIIDCCFGGIDHHIJJJJIJJJIJJIGIJIGIGGIIGGIJJHHHDEFFEEDEDDDDECDDDCDDDDDDDDDDEDDDD
@1LN
GGGAAAGACAGAAAAATAATTCTGTGGGATCATGATCTGAATCCTGAAAGAGAAATAGAGGTTCCTGATCAGTATGGCACAATCAGAGCTGTAGCAGAAGG
+
@CCFDFDDHHHHGIIIHGHIJEHJIJIIHGHEGGBGIJJJIJJGHHFDFHIJJIHBGBFHEIIIIIIGIEHGGHHEEHFHFFFDFECCCEDCCDDDCCDDB
@1LO
CAGGAATGTATCGGGAAGGACCCACATACCAACGGCGAGGATCACTTCAGCTCTGGCAGTTTTTGGTAGCTCTTCTGGATGACCCTTCAAATTCTCATTTT
+
@CCFFDEF?CDFHIIGGIJHGIIJJJIJJJJIGIIIIIJIGFHHFFFFFECCECCECCBACDDDDD9ACDDDDDDDDDC@CCA@BDCCDCDDCADDEDDED
@1LP
AGGAAGAGGACAAGTGCAAGCCTATGTCCTATGAGGAGAAGCGGCAGCTCAGCTTGGACATCAACAAGCTCCCCGGCGAGAAGCTGGGCCGCGTGGTGCAC
+
CCCFFFFDHHDHHJBFGHJJJIIIIHHIIGGIICGEIHDIJJGIJIGIJJIICHHIGHHHHHFFFFFEDEEEDDDD=@@@@DDDDDDDDDBBB59<2<C@C
@1LQ
GCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTC
+
CCCFFFFFHGHHHJIIJJJJJIJJJIJJJJJJJDHGIJIFIJJJFHGIIIJJJJHHHHHFFFFDDEEDEDDDDDDDDDDDDDDDDDDCDDDDDDDDDCDD
@1LR
AAAAATAATGGTGGAAGATAAAGTTTCTTTTGAAAATATGACTGTTGGAGAAGAAAGTAAGCAAGAACAGTTGATTTTGGATCACTTACCATCTGTAACA
+
@@<DBDDDFHHHFHIEGHGGIJIAHIBHGGGIGHIJJJIGEAGEHIJIBGFGCEDFG9BEGIIGGGHIJJJJIIIIGGHHFDFFDECDEEDCCCC@CDCD
@1LS
GGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTC
+
CCCFFFFFGHHHHJJJJJIJJGIJJJJJJIIJIGGIJGJIIIJJJIJJIICHGGGIJJIGGIFHHEHHHFFFFDDDEBCDDDDDDDDDDDBDDDDDCDDDD
@1LT
GGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTT
+
?;?DDDDDH?ABBHDBEG@ACA?FFDH>G?@C;FDDFFBB??GGCFGDHDFD<B;2BHFG>D@7=D@HE=EE;7@D>;A;9?AA=;??BACCD:CACCAC
@1LU
CGGCATTGCCCAGGCTCTGCAGCCACATCCGACCGAGTCGTCCATGTACAAGTACCCTTCTGACATCTCCTACATGCCTTCCTACCATGCCCACCAGC
+
@@?AB?D;CC??CDGIBF@GACGG>FBEEGA=DG@7@CBBGGHG>C==CHHA?AE?ADEEB?CCC@CCCCCACC<@>AACCCCACB>>@C@9>8>?B@
@1LV
CTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGATATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCT
+
=:1A++2<<+@=?A0C)+?C<*:@@7:5)100?::7**94<=BB>**0>B)>.).3A=BBBB>:(..(;.(;,.,55;(;39(55;6',(9<1+38=3+9=
@1LW
CGTGAATATGGCATTCTCTCAGTCCAACCCTCCTTCGGAGTTGCACAAGGTCCACGGATCCAGAAACAAGCCCACCAGCTTGTGGAACCCAACGTACGGCT
+
>712=7<?<22A22+<2@>+3<3@=73?<121?171?:::?B?*9905=2//8)8(---;7)=AAA>><@=;=;;==2(5,55,(;9>=;(92+988)0.0
@1LX
CACCTCTCAGACAACTAAGACAGATGACCCCCAATTGAAAAGAGAAATAAGGTTAATGAAAAACAGAGAAGCTGCTCGAGAGTGTCGCAGAAAGAAGAA
+
@@?DDD?DHHHHHGGIIGE:CBC>HD@HFCEHIIIIIIIEBF@BDHGHEIGG=FBCGGIHIIIIIIIDEHEEEEEEECC@=>-;C>=A@BBCCCABCCC
@1LY
GTTTCACCCAACAGATGCAAATACCATAATTACATGCGGTAAATCTCATATTTTCTTCTGGACCTGGAGCGGCAATTCACTAACAAGAAAACAGGGAATTT
+
@BCFFFFFHGHHHJJJJJJJJJJJJJJJJJJJJJJJJJJHIIJJJJJJJJJJJJJJJIJJJJJJJJJJJJHFFDDDDDDDDDDDDDDDDDDDDDDDBDDDD
@1LZ
AAGGAATCATCACTTAGAGCAACTCAACCAAGTGAAAATGATAAACTTCAGAAAGAACTCAATGTACTTAAATCAGAACAGAATGATTTAAGGCTAC
+
CCCFFFFFHHHHHJJJJJJFJIIJJJJJJJJIDGIIJJJJIJJJJJJFIJJIJJJJJJJJJIIJHGIIJJJJJGGIJJHHHHHFFFFFFFEEEEEED
@1M0
CGGATAATGACTCAGTGCTGGCAACATCAGCCTGAAGACAGGCCCAACTTTGCCATCATTTTGGAGAGGATTGAATACTGCACCCAGGACCCGGATGTAAT
+
=<=AAAAA?B8CBBC,<<A=<1@B+7<AABBBB;;BAA;>BAA<;ABA94?9>>>>AABBBBBA>B><<AA>;>>9);>>>@@?=;;=;5,;7;;;;3::3
@1M1
CAGGAGATATGCAAACATATCAGATCCGAACTACACCTTCAGCTACTTCTCTGCCAAAAACTGTGGTGATGACATCTCCTGTGACTCTCACCTCTCAGAC
+
@@@AD<DD<F?<CGI@?AC@HHGED@3ACB1?F*?CGGHG<:4BDBD@4??BFF3C).B@AHC=)=@5CA)==?A?@BB@);A>;.(-->>=;?A>:;>>
@1M2
AGCAGGGGTGCTGAAGGATCAGTTTCTAAAGTAAATAAAAGTTTTGGTGAAGAATCAAAAATAATGGTGGAAGATAAAGTTTCTTTTGAAAATATGACTGT
+
CCCFFFFFFHHHHJJJJJJJJJJJJJJJJJJFHIJJJJJJJHIJJIJGHIJJJIJJJJJJJIIIJJJAHHHFFFFFFECDEECEDDDDDDDDDDFEECDDD
@1M3
CTTCTCACCAGGGCCTTGGAAGCACTTTGCCTAGAAGGGGAACCAGGAATGCCATAGTTCCGAGAGAAACTTCTGTTAGTAAAACACACAGGTCAGCAGAC
+
@@@DDBDDDF?7F7EHHBGI@GACGGGIEGFGIIIIID<DDGHIBHGGIIIFFGI@H@=CCG8=<BBC>6;;@CCDCCC5>CCC>BBBBB9?4@CCCCB?A
@1M4
AGAAGGCTGTATGTTTGAAAAGGGCCCCAGGCAGTTTTATGATGACACCTGTGTTGTCCCAGAAAAATTCGATGGAGACATCAAACAAGAGCCAGGAATGT
+
@B@FFFFFHHGHHJJJJIIJJJJJJJJJJJJJJJHJJJIJJJJJJJJJJJJIJIIIJIJJJIIJJJHHHHFFFFFEEEDEDDDDDDDDDDDDDDDDDDDDC
@1M5
CAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACT
+
C@@FFFDFHHFHGJGIJJHIJIIIJIIIIIHIIGIJJJJJGIJJIJJJJJDFHIJJJJGJJJJJJJHHFFCDEFFEECECDD
@1M6
CCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGC
+
CCCFFFFFHHHHHIHGIJIJJIJHIIIJJJJJFHIJJIHJHIJIJIJCHJJJJJJJIIJJJJJIHHGHHHFFFFFDDDDDDDDDDDCDDDDDDDDCBBCAB
@1M7
CTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTAT
+
CCCFFFFFHHHHHJJJHIJJJJJJJJJJJJJJJJJJJJJJJFGIJJIJJJIHEEHHHFFFFFFEEEEDDDDDDDDDDDEDDDDDDDDDDDDDDDDDDDDDD
@1M8
GTCCTGGAGAAACCCTAATACCTGGGGATACGGAGAGCAGTGTGATTCCCTGTGGAGGCACAGTTGCGGCAGCTTCCCTAGAAAACAGAAACTATTGCAGC
+
+=+AAAAA+7?@7=A=2+<?@<@B3+):4)??A50:)0==B397*7?4A)>7).=>(15(.).7))7',33=(,((59(55(5(8((+8=8;(8(8883;7
@1M9
GTCCCAGAAAAATTCGATGGAGACATCAAACAAGAGCCAGGAATGTATTGGGAAGGACCCACATACCAACGGCGAGGATCACTTCAGCTCTGG
+
@@@DDDDDFFDHD@E;CDC@GEDBGHEGIICGI;DD@DFH@FGGFGDHHIGFGI7;FCFHIGIIFECEHEE>ABB=<BA?ACCC<>A>>ACCC
@1MA
AAATGAGTTTTCTTTAAGGCCAATTGACAGCAACACGTTTGAAATGAATGGCAAAGCTCTCCTGCTGCTGACCAAAGAGGACTTTCGCTATCGATCTCCTC
+
B@@DDFFDFHHHHGJJIIJJJIJIGJHIIIJIIGHGGDFHHIIJIJFIGGIJJJGHIJIEGGGGGJIIGIIHFHFEDEDBAAEEEDDDDDDDDDDDBCDCD
@1MB
TTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACC
+
CCCFFFFFHHHHGJJJJJJJIJJJJJJJJJIJJGHIIJJJJJJJJJJJJJFIIBFHIIJIJJJJIJHHHHFFFFFEEDEECCDDDDDDDDCDDDDDDCDDD
@1MC
CTCCTGCTCAGGGTAGCATTAAACAGGAACGAATTTCATATACACCTCCAGAGAGCCCAGTGCCGAGTTACGCTTCCTCGACGCCACTTCATGTTCCAGTG
+
=>1+<2+?2A=+@+@+?<AAB@,3?CC;+)1?)?AB?<?A<AB?<09>A7/?7>5;(-(...>A654;=>3;=;;,(((3/36-0-0;;3(+38=:88883
@1MD
CAGCAATGTGAGCAAGAAGGAGCCAGCGCCCATGAAGAGCAAGCCCCCTCCCACGTATGAGTCGGAGGAAGAGGACAAGTGCAAGCCTATGTCCTATGAGG
+
@@@DDFFDHGHHFEHGEHCF>GHIC>E@CFDFEGGGIIGH@FIIHGHHJJJJ>EA6=@C>D;BAD>BD<BBDDDDDD?B:@CCDD<BCCCCC@DC@CC@C?
@1ME
GATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCC
+
@@@FFFDFFDFDDGGGEGGHGHHIJJIIJIJJIIGGGIJIIJGEGGIIJGIJIJJJJJIIGHEHHHEFFFFBDDECCDEDDDDDCCD@AA@CDBD???CCB
@1MF
CAAATCAGCAAACAAATCAAAGCTCATGATGGCAGTGTGTTCACACTTTGTCAGATGAGAAATGGGATGTTATTAACTGGAGGAGGG
+
@@@DDDFFHGHHHIJJJJJJFHIIJJHJGIGIJIJDFHICGFIIEIFIHJGGGIDHI@F@FHIIJJGGICHEIIEHHHHH;BE1?CD
@1MG
CGGATAATGACTCAGTGCTGGCAACATCAGCCTGAAGACAGGCCCAACTTTGCCATCATTTTGGAGAGGATTGAATACTGCACCCAGGACCCGGATGTAAT
+
CCCFFFFFGHHHHGIFGIGIIIJJJJJJJGIJJJIIJIJIJJJGIGGDHIIIJIJGJGIJJJIJCEDHFHFFFFFFFECEDDEDDDDDBDDDDD<BDCEEE
@1MH
TAAACACAAAAATAATAGAAGAAGAAAAGAAAACTCTTGAGCTAAAGGATAAATTAACAACTGCTGATAAATTACTAGGAGAATTACAAGAACAGATTGTG
+
@@CFFFFFHHHGHGIJIJJJIIJJJJIJJJJJIJJJJJIIJJIIJJJJIJJIIIJJIJJJIJJIJJIJJIJIJHGFGHHFFFFFCEEEEEDDCDDDDDDAC
@1MI
GTCCTAATAGTAGAAGAACCCTCCATAAACCTGGAGTGACTATAGGGATGCCCCCCACCGTACCAGACATTCGAAGAACCCGGATACATAAAATCTAGAC
+
=:8+4ADDBB==2A,2<;@B)A?EFHBHBCG9E?FD*):?DF4D<DDC9B(?;@F'@AE'.61(7).;;@(5;A?@>559=B-9-5:4>:>@A@A:3:>A
@1MJ
CTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGC
+
C@@FFFD?BHFAFGGBFFGEGIGIIGIGIHIGIIGGIIIIIIBGDHGHIHHIHIGGCDEHGADHIEHFHFFFDDFCACEEEEDDDABD5?CCDDDDDCDC
@1MK
ATGAATTACGACAAGCTGAGCCGGGCCCTCCGTTATTACTATGATAAAAACATTATGACCAAAGTGCACGGCAAAAGATATGCTTACAAATTTGACTTCC
+
@@CFFFFFGHHDHGIIIIIGHHBHIGJJGGIGFGGGHGIGIGGJIGIIIJIJFHHHHCHDDFFE;AEEEDBDBBDDDBCDEDCEEDDDDDDDBDDDDDCC
@1ML
CAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACC
+
CCCFFFFFHHFGHIGIHIGHIGGJJJJJEGGJJJIJGGCHJJJJIJJJJIJJIIJIIJHHGHHFFFFDE@CCDDCDB8;CCDDCCCDD>?CCDCDDDEEDD
@1MM
AACCAGCAAAAGGAAGATGCCAGTCCTCTACCACCATGGTTAGCAATGGCTTTTCCTAAGAGTCCATTACCGCCCCATTCAAGTGGCCATTTAGTGGCTTT
+
;((:=73)).):((<(2)24)4).<>1)6=1))1(8=.).))0)99)).()0)))))/9.)))/)8.).).'',5'6((-99(7(((,;<;(,:((,((((
@1MN
CCTCTCCTGGTCTCTCAACAGGCAAAACGGGAGGAGGAGCGCAGCCCAGCTGCCCCACCACCTCTGCCTACCACCTCCTCTGGCAAGGCTGCAAAGAAACC
+
@@@FFFDAADADHHEHGICBCHGE>GIJGHGIII@D8?(?:FAEAEHIHCC3?BBDDCDDDDDDDCCCDDDDACDDBDCCDD@ACC?B?3<@DDDDD@DCD
@1MO
CCACACCTGGGAAAGGACCTAAAGGTGTATATCAAATCAGCAAACAAATCAAAGCTCATGATGGCAGTGTGTTCACACTTTGTCAGATGAGAAATGGGATG
+
CCCFFFFFHHHHHJJJJJJJJJJJJCFFHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJEHGHHHHHHFFFFFEEEEEEDDDDDDDDDDDDDD
@1MP
CTCTTAGAAGAGAAGAATACCATGTATATGCAGAATACTGTCAGTCTAGAGGAAGAGTTAAGAAAGGCCAACGCAGCGCGAAGTCAACTTGAAACCTACA
+
CCCFFDDDHHHFFHGGIGHGFCHHFEGGI@HDEHHIIIIJGDHHIIJJIEHCGGIIJFGIIAHIIGFGIIIG@GHDEFD;BBDDDEDDDDDDDDDDDDCD
@1MQ
CAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTC
+
CCCFFFFFHHDHFGI?EGHGIJIJJIEEGHHHIIIIJIJJJJJIJIIIIJIHGHGJGEIGIIJJIFGEFDFFFEEEEECCCCCDCCCDDCDDDEDDCDDD
@1MR
AAGAACTTCAGAAGAGAAATCATAAAGACAGCCAGTTCGAAACTGATATAGTACAACGAATGGAACAAGAAACACAAAGAAAGTTAGAACAACTCCGGGC
+
???+A:==2,=A+A+22+<::FF?:+39CECDE))***18))?<0*9?<DEDD<B>*7BC=C)..)=@7=?=ADD=@;;;;;;;;>;5;>;,5(,,<?;3
@1MS
GGATGACCAGCGCGACCTTATCTCCAACAATGAGCAACTGCCCATGCTGGGCCGGCGCCCTGGGGCCCCGGAGAGCAAGTGCAGCCGCGGAGCCCTGTAC
+
??1DBDBD?A3CFGIIIIEDAGDDF??FBBG<?89BFD3B<FFFC@=7@EFIFB4>B?:8-220&008BB;950+(43?44:>(48@<>5@B7<?38+4>
@1MT
CCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTC
+
CCCFFFFFHHHHHJJJJJJJJJIIJJJIJJJJJJJJJJJJJJIJJIJJJJJJJIIIJIGFGGFHHFFFFFFEEEEEDDDDDDD@DBCDDDDDDDDDDDDDD
@1MU
CCTGCGCTTGCAGCCAATTTACTGGAGCAGGGATGACGTAGCCCAGTGGCTCAAGTGGGCTGAAAATGAGTTTTCTTTAAGGCCAATTGACAGCAACACGT
+
CCCFFDDFHHHHHJJJIIIIJIJJJIIJJJJJJJJJGJIJFJIIGIGGGGCHIIHCDGHHHHFFFFFFEECEEDEDDDDDDCDBDDDDCCCCDDCDBBDDB
@1MV
CAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTAC
+
@@@DDDDDD?CFAHIIDFHHGIIIGGECCHGIIIIIIIIIII<G@FHGFEGHFHGEHIHHE>@BCCA>@BBB8??B@BCCCC>@44>CC>CB?C4>@:CC3
@1MW
GAAAACTACAGAGGAACTAAATGAAGCTTTGTCAGCAAAGGAAGAAATTGCTCAAAGATGCCATGAACTGGATATGCAGGTTGCAGCATTGCAGGAAG
+
@@@FFFFDHHHFHJHHIIIGGECHHGIIIIJHEGIGIGBCC@FDAHIGIHIHJIIIIFCFGHGIGGICFHIGIIBHEEEHB@CDDC@BEACCDDD@BD
@1MX
GATAATCAGCGTCCACTGCTGAAGACAGACATGGAACGTCACATCAACGAGGAGGACACAGTGCCTCTTTCTCACTTTGATGAGAGCATGGCCTACATGCC
+
CCCFFFFFHHGHFHIIJJJIJJJJJJJJIIJJIHJJJGHIJJJJJJJJGJJJHIJAHIHHHHFFFFFFEEEEEDEDDDDDDDEDDDDDDDDDDDDDDDDDD
@1MY
CTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTAC
+
@@@FFFFFHFDFAGGIIIJJJIEHHHIHEHIEIGDDDGGIIIGDHEFFGHGEEHHHBHFFDC@DBCC>ACDACDDCCDDDCCDBCDDCACCDDDDA<9BCD
@1MZ
GCAGAACAAACCAAAGAAAAAGGAGAAAGACAAGAAGGAAAAGAAAAAAGAAAAGCACAAAAGGAAAGAGGAAGTGGAAGAGAATAAAAAAAGCAAAGCC
+
CCCFFFFFHHHHHJIJGHJJJJIFHHIIJGIJJIHJIIIIJIJIJIGIJJFIIJIGHHHHFFFDEEDECCDDDDACDDDDDDCDDDDDDDDDDDDDDDCD
@1N0
GCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGT
+
===AAA>4A77+2++2<?@4<=A<3?<C@ABBBB3??A?A?AB;3>AAB5ABA3=1).8ABBBA>AA>-:<@@@@=>>?==?=;=?;(9=9;9=?????(+
@1N1
AGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGG
+
CC@FFFFFHGGHHIGIJJIIJJJIJJJJIJJJJJJIJJJJIIJJJJJJJJHGIIIJIJIIIIIIHHHGHEEDEFFFECEECC@CDCDDDDDDDDDDDDDDD
@1N2
ATGGTTGGCAGTGCGGCCAGCCAAAGCTTTCCCCCTCCTCTGATGATTAAACAGGAACCCAGAGATTTTGCATATGACTCAGAAGTGCCTAGCTGCCACTC
+
BB@FBDFFHHHHHJJJJJJJJJJJJJIJJJJIJJJJJJJJJIIJJIIJJJJJJJJHHHHFFFDCEEEEDDDEEDDEEDDDDDDDDCCDDDDDDDDDDDDDD
@1N3
AAAAAAAAAGAGGAATCTCATTCTAATGATCAAAGTCCACAAATTCGAGCATCACCTTCTCCCCAGCCCTCTTCACAACCTCTCCAAATACACAGACAAAC
+
CCCFFFFFHHGHHIJIGIJJJJJJJJIJGIJJJJJIJJJJIJJJJJJJJBHIHHFHGFFFFFEDEDDDDCDDDDDDDDDBDDCDDDDDDCDDDDDDDBDDB
@1N4
CTGGACAGATAGCTGGCGTGGATAAAGATGGAAGGCCTCTACAACCCCACGTCAGAGTGTGGGATTCTGTTACTCTATCCACACTGCAGATTATTGGACTT
+
CCCFFFFFHHHGHJJJIJFHIHJJJJJIJJJIJJJJJJJJJJIJJJJJIJJHIIIGH=AAEFFFFEEEEEDEDDDDDDDDDDDDDDCCDCDDDDEDDDDDD
@1N5
AGATTAGTGGGGAGAGTGATGCTGACTGGCCGCCGGTGGAAGGTAAAAAAGATAGGTGGGGATCTGCCGAGGCAAAGTAAATGAGTGGCGGAGGAAAAGA
+
((0(24))2(8((-((..))))211))2<<((-((''''())(.).).)'3(((((76(32('((4(())&&)(((++4((((((((++&&)&&((+((+
@1N6
GAAAAACCACAAGGACAGAGAGAAAAAAAAGAGGAATCTCATTCTAATGATCAAAGTCCACAAATTCGAGCATCACCTTCTCCCCAGCCCTCTTCACAACC
+
@@@B?=@BFFHFDHHGGGHIHI<F>GE>GGF7@FAGG7C;7CDHEEH;@EHDHHHGHEBDDCBBCCECDC>BC:AC?>5?ACCABC?B@B?A?C@CCCCBB
@1N7
AGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTAT
+
CCCFFFDFHHHFHJJJIJJIIJIJJIJJJJJIJIJIJJJJJJJJJJJJJJIJJJJJGHIGHHHHFFFFFFDDEEDDCDDDDEDDDCDDDDDDDCCDDCDDD
@1N8
AGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGC
+
@<??DDDDD?DBFB@F@EBHIC=@DG?:BGIIG;BGHIDGGGFA@FC;@ADCEEEFC@B7?CB@A:;A6;>A;@CBC85,:@C::A@8?9<CCCB@?CCA
@1N9
CAGCTACTTCTCTGCCACAAACTGTGGTGATGACATCTCCTGTGACTCTCACCTCTCAGACAACTAAGACAGATGACCCCCAATTGAAAAGAGAAATAAGG
+
CCCFFFFFHHHHHJJJJJJJJJJJHIJEHIJJJJJJJJJJJJIJJJJJJJIJJJJJJJJJJJJJJJJJJJIJJJHHHHHFFDDEEEDDDDDDDDDDDDDDD
@1NA
TGGAACAAGATAAAAAAGTAGAAAACTCAAATAAAGAAGAAATACAGGAAAAGGAGACAATCATTGAAGAATTAAACACAAAAATAATAGAAGAAGAAA
+
<?7DDABBFHBCFFIIII:AH?ACEEGHGIHBHGD>CFGIIGIIIIIGEGIIGIGEG@GHGGIIIIHHFCHDEDEEDDCCCBBBBCCADCCCC?CCACC
@1NB
CATGTACAAGTACCCTTCTGACATCTCCTACATGCCTTCCTACCATGCCCACCAGCAGAAGGTGAACTTTGTCCCTCCCCATCCATCCTCCATGCCTGTC
+
?;@D?DADHBHHFBG@HC3FCFHIGIE@FGGDFHHC@FHEFHGHIIDCGGIIBHEEBHGGIGGG@=CHHGB;@DGEE=EE;@@CCCCCCCCCACCC@>::
@1NC
CCTCGAGGCCGACTTCCTCTGAGCCAATATTGTCCGTATTGCCATCTTAGACTTTGCCCCCTGCGAATCAGCGGGGGGCGTGGCCACACTGGTGTACATCT
+
((7((0(((:(88(88)=?))1:)9.6:7.)9?13-.0(93).))))/)<)).3);)8)('-9(5==',3(-','&0&8-)&)&((((+3(+(++((((((
@1ND
CTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGAC
+
@@@<BDEDABHHFGGEFFGG?AEBDHG@G<?@D?:3BDBD@FBADF?FF<CF9=B<C=>DGG=;@7AEHEB@EDECEDD@>@??9AC<:@@CD@@:?.9
@1NE
GGAGAAGCGGCAGCTCAGCTTGGACATCAACAAGCTCCCCGGCGAGAAGCTGGGCCGCGTGGTGCACATCATCCAGTCACGGGAGCCCTCCCTGAAGAATT
+
1+1+@A3+)<07<2+@A=B<:7)11?A>A7::97)9//7>:-:/963355;5515(377&00;0;33+:(33:8((+++:-55&)0+8(++8;888(88(8
@1NF
AAGAAAACAGGGAATTTTTGGGAAATATGAAAAGCCAAAATTTGTGCAGTGTTTAGCATTCTTGGGGAATGGAGATGTTCTTACTGGAGACTCAGGTGG
+
?@8BBDBDCDFAHBDCCE@@@:A??CFEEGGAF9??FHAGC?B@?D@<F8B=8B<=.8==88@7=6AHF27;?(?;@66;ACC>>>>>2??:>@5?:>?
@1NG
ATGTTATTAACTGGAGGAGGGAAAGACAGAAAAATAATTCTGTGGGATCATGATCTGAATCCTGAAAGAGAAATAGAGGTTCCTGATCAGTATGGCACAAT
+
@CCDFFFFHHHHHJIIJHHIJIJJIIJJJJJJIJJJJJIIJJGHIJJJGIJJIJJJJIJJJGHIJJJHHHFHFDFFFDECEEEEDDDDEDDEFEDDDDDDD
@1NH
GGAACCCAGAGATTTTGCATATGACTCAGAAGTGCCTAGCTGCCACTCCATTTATATGAGGCAAGAAGGCTTCCTGGCTCATCCCAGCAGAACAGAAGGCT
+
@@CFFFFFHHHGHJJJJJJJJIIIJJJIJIIJGHIIIJGIHIJJJJIIJJIJJJJIJJJGIIJJJIIHGIJJHHHHHFFFFFFEDDEEDDDDDDCDDDDDD
@1NI
CAGAGAGAAAAAAAAGAGGAATCTCATTCTAATGATCAAAGTCCACAAATTCGAGCATCACCTTCTCCCCAGCCCTCTTCACAACCTCTCCAAATACAC
+
@@@DDDDDHFF>DBGHI@FEGDCHDGE@AEGH>B>F@GGEH8BBBB=FH>78@GH@BHCHEE@CECCCCCCBABBCB?C>CCCC?B9?CCCCCACCCAC
@1NJ
GGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGC
+
BC?DFFFFHHHHHJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHHHFFFFEEEEEDCDEDEEDEDDDDDDDDDDDDDD
@1NK
CGGGTTTCGAGTTATGATTGTGAGATTCCTGGTGGGTAGATTACAGTGGGACAAAGAATTGGGTGTGGGTAATTTGGAACAGACTACAAGGGAAATTGGC
+
7((22((283@.(29<;)))))))))).)<=)8;=4()(>)).9:>).)3=7(9=?>:..:7(-'-8='').31.:8;(9((((,5(((,,2;(((+5/5
@1NL
TGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCT
+
::+=AD8BF=AFFCEHCH?EH@HGEDFGHGHIIIGFEHGGGCHEHDGDB?@FEGHIIGGGIII)=7@7?A>;CEC;@C?CC>C@>CCC??CCCCCCCAC??
@1NM
GAGCAGCTTGCAGCCCTCTCTCAGCCCCAGCAGAACAAACCAAAGAAAAAGGAGAAAGACAAGAAGGAAAAGAAAAAAGAAAAGCACAAAAGGAAAGAGG
+
@??DDFDDFHDDHIIJIIGIGFHHJIIGIIIGIEHGIJJJJJIGIJJGADHIFIGCHGIHFHCEFFFBECCCBBDDDDBDBCCABCDDDDDDDDCCDCDD
@1NN
CCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGG
+
CCCFFFFFHHHGHJJJJIJJJJJJJJJJJJGHJIGJJJIJJJJIJJJJJJIJJIJIIIJJJJIHHHFFF@DEEEEEEEDDDDDDDDDDDDDDDCDDDDEDD
@1NO
ATGGACAGCAGATACTTGTGCCCAGCAATCAGGTGGTCGTACAAACTGCATCAGGAGATATGCAAACATATCAGATCCGAACTACACCTTCAGCTACTTCT
+
CCCFFFFFGHHHHJJJJJJJJJJJJJJJJJJJJFHIIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHHHHFFFFFDDDDDDDDDDDDDDDDDDDDDDD
@1NP
CAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTAC
+
@@CBD8DDFHHHHIIIEGIIICFH@FGGCIIIIEGGHIIFGIEGHIGEAFHDFA:EH<EEF38?CCCCB<?BBCBCCCC>CC>CCCCCCCCBC?>ACCDC>
@1NQ
CTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTAT
+
@CCFFFFFHHHHGJIJJJJJIJGIGIJJIJIIJHGIJJJJJ;FGGIIIIJIH?CHHHFFFFFFDEEEDDDDDDDDCDDFDDCDCBBBDDCDDDBDDDDDDD
@1NR
GCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACC
+
@@CFFFFFGHHHHJJJJJJJJJJICHHIIJJJIJJIIJJJJIJJBFGIJIJIDHIIJJJJJIIIIJJJHHHEEFFFFFDEEEEDDDDDDDDDDDBDCDDD
@1NS
AAACAGAGGATTTTAGTCTATATGCTTGTGCTTCTCCAAAAACACCCATCCAGGCAGGGGGATATGGAGAATTTGCAGCCTTCAAGTAGCCACCATCATGG
+
@@@DDEDFHGHFDFB@EGEGCFI<HEHDEEEF@GAHI>FGIEHCHGHDBGDEHGCHGFEEB8?DDCECAC=;ACCCCCCBCACCCCDCAAAC?AAACCCCC
@1NT
GTGTTGTCCCAGAAAAATTCGATGGAGACATCAAACAAGAGCCAGGAATGTATCGGGAAGGACCCACATACCAACGGCGAGGATCACTTCAGCTCTGGC
+
@@CFFDDF8DFHFHIJIGJIEGGIIIGGIIJJJJIJJIHHJGJIIJJJEHDBFHIIIGHADHEHHFFFCECECEDB@BB>@@BDABCDDDD:@C@CCCC
@1NU
GGGCTATTCCACAAAGCCACAACTGGCTATTGTTACCCAGTGGTGTGAGGGCTCCAGCTTGTATCACCATCTCCATATCATTGAGACCAAATTTGAGATG
+
@CCFFFFFHHHHHJJIJIJJJJJJJJJJJJJJHJJJJJIHFGIDGHICHJJJGIJJJJJJJHHGIJJJHHHHHFFFFFFFEEEDCDDDDDDDDDDEDDDD
@1NV
CTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTC
+
@C@FDADEHHGDHEDHIGGGG@HIGHIFHIGGGDGE?GHG>GHIID@FBGGIHIIIIIIGBGIIHGGGEEHEEEDFFEFEECAEEBDDB?>CBDCB>ACCD
@1NW
ATTTTGATGAAAATTGGCAAAACACAATCAAAACTGTGGTTGGAGAAAATTGGAAGATATAGATAAGCAATTTAAAGAAAATTTTAAAAGGTATCTTGGAT
+
1;9;=<(8)2<=@))<69.):71:((-)2<3).9)..)))0-(.96.6=<)93:3:(/)))88))..))8;<)<>9)=97)).:=(691-(((-((7(57;
@1NX
ATCCAGTCACGGGAGCCCTCCCTGAAGAATTCCAACCCCGACGAGATTGAAATCGACTTTGAGACCCTGAAGCCGTCCACACTGCGTGAGCTGGAGCGCT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHHHFFFFFEDDDDDDDDDDDDDDDDDDDDDDDDDDDDDD<BBDDDDDDDCDDD
@1NY
GGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTC
+
CCCFFFFFGHHHHJJJJJJJIJIJJIJIIJJJJJJJJJJJJJJJJIJIIJGJJJJJJJIIJJHHFFDDEEDDDDDDDDDDDDDDDDDDDDDDDDEDDDDD
@1NZ
GCAAAAGATATGCTTACAAATTTGACTTCCACGGCATTGCCCAGGCTCTGCAGCCACATCCGACCGAGTCGTCCATGTACAAGTACCCTTCTGACATCTCC
+
=??=DDB+2AAD22A4+A?F:CF:A::,A9CEFD<D):****00?D>2B*B98BB===)))41AA<??=?;,(,<>>;;>:5+::(((4>3>34:>A>>AA
@1O0
ATGACTCAGTGCTGGCAACATCAGCCTGAAGACAGGCCCAACTTTGCCATCATTTTGGAGAGGATTGAATACTGCACCCAGGACCCGGATGTAATCAACAC
+
@CCFDFFDB,AFHEAGGEGGIEHIDIDFEHDCEGFHGHGIGBHFHEIHHIGCD@CHIDAD>@@G7@7?>;?E;@DEFDBABD=ABBBDB@>:@CDEDCCCD
@1O1
CTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGC
+
B@@FFDDFHHHHGJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJIGIJJIIJJHGIIJJIJIGIJJHHHHHHFCFFFFEEEEEDDDDCCCDDDDDDDDDBDD
@1O2
TTTTTATGGTGGGACGAGGATACCTGTCTCCAGATCTCAGTAAGGTACGGAGTAACTGTCCAAAAGCCATGAAGAGATTAATGGCAGAGTGCCTCAAAA
+
CCCFFFFFHFHHHJJJJJJJIJJJJJJJJJJJJJJJJJJJHIJJJFGIJJGICEIIIJJHHHHHFFFFFEEEEEEDDDDDDEDDDDDDD>CDDDDDDDD
@1O3
CCAACAGATGCAAATACCATAATTACATGCGGTAAATCTCATATTTTCTTCTGGACCTGGAGCGGCAATTCACTAACAAGAAAACAGGGAATTTTTGGGA
+
@CCFFFFFFHGF?FHIJGIGGEEHIGHII3CE?FGHBCGHI>FIBDBFHIGHIGCGEHIGIGGHIGFFFFACEACC>CCDDDCD>ACDB?BBCCDC9@DB
@1O4
GCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGT
+
?@=:=BD;FB::AA<FFFFEFGC>GA<+<A?CEF<06:?90?DB<34.=BBFEE@7=.==7@E>=)7=A7;@);>;((;A>>?@?BBB59<?@BB9(89@A
@1O5
TACCAGTCCACGGATAGTGAAGATTGGAGACTTTGGACTCGCCAGAGACAACTATAAAAATGATTACTATAGAAAGAGGGGGAGATGGGAAGAGCGGCGTG
+
7:7=A@=@C4?=)<81+23,3??+<++?@*:*?=<**0??):=<((7=A>)6>)=>A>;;A)>)=>>.>;).;>?3>((',7'00((+((+282;&&095;
@1O6
CTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGG
+
??<?BDD@@C1@FI;@?ACCGD*CF?CFGGIIIIIFIEEE@9FEE>C;@6=CAE@DDBDDCCCC1;7=<2<BB:>:9???@BBBABAAAA@>B>??BB4A
@1O7
TGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGG
+
CCCFFFFFHGHHHJJIIJJIIIJJJIJJJJJJJJJJIJIJJIJJIJIJ@EHIIJHHGDFFFDCCDCDDCDCDDDDDDC@CC:@CDACCDC>CCACDDDC?B
@1O8
CATGCCCACCAGCAGAAGGTGAACTTTGTCCCTCCCCATCCATCCTCCATGCCTGTCACTTCCTCCAGCTTCTTTGGAGCCGCATCACAATACTGGACCTC
+
CCCFFFFFHHHHHJJJJJJGHJIJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJIIJJJJJJJJJJIJJHHHGHHFFBEFDDDDDDDDDDDDDDEDDDDDD
@1O9
GTCTGGATCCATTTTGTGGATGGCACCAGAAGTCATCAGAATGCAAGATAAAAATCCATACAGCTTTCAGTCAGATGTATATGCATTTGGAATTGTTCTGT
+
CCCFFEFFHGFHDHJGFG=DHCGGHCHGIJGC?FHIEGIGIJGIIJJEHGEHJIIIIIHIEHIG<F@FHGHJID>7A7?=EHHFF>@CFF>6>CEECDEDC
@1OA
CTTGATTAGAGACCAAGGATTTCGTGGTGATGGAGGATCAACCACAGGTTTGTCTGCTACCCCCCCTGCCTCATTACCTGGCTCACTAACTAACGTGAA
+
@@@DD?DDBF>AD=DEG<CCAFEEGBFHA4?FCDGCEFAFGHGGD@@D@DCEHCHECACH>66=?BB;?AAC>CC>CC>CBB?A@>A<>A@C@@BC<AB
@1OB
ATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGAC
+
@@@DDEBDDDBDHBHBGIBHGGIGIJDHE>EFG@FFDDE?DHHEIIDHIHG>88=AFDFGCHHDEAEHB>AED;BBC@CCEBAABAB@;B8@<ACC4@C4:
@1OC
CTCAACTCATACACCGAAACCTGACCGGGCCTTCCCAGCTCACCTCCCTCCATCGCAGTCCATACCAGATAGCAGCTACCCCATGGACCACAGATTTCGCC
+
@@@FFFFFHHAHHJJIHIJEGIJIHFIEGGGHGGGIJIIFGIJIGHHGGHGFCHDB;>=CEDCDDDCCAD>CDDD@DDDDDDB?CDDCCA<ABDDDDCCDD
@1OD
CACAAAGAAAGTTAGAACAACTCCGGGCAGAGCTGGATGAGATGGATGGGCAGCAGATAGTGCAAATGAAACAAGAATTAATAAGACAACACATGGCAC
+
@<@DDDD?F?>DDEF?B+AEF?EFB@8CFF)BBFFFEEBEAFII*9BFFIC=ACEFDEAE7=?EFD@DDD>7@@;A;;5>B>A;>ABBBBB??BBB1>:
@1OE
CCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGT
+
CCCFFFFFHHHHHJJJJJJJHGJJJJJJJJJJIJJJJJJJIJJJJJJJJJJIHHHHHHFFFFFFEEEEEDDDDCCDDDDDDBDDDDDDDDDDDDDDDDDDD
@1OF
GGGAAAGCGAGAGGGAGACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGG
+
;?<DDDDDD;@DCBDFB@FB<1?@FFF=DFIDFC>FIEIFIFCEFDBDCBBAC33;;/;B=BB?BBB>ABABBDBB4:@>:@ABB?B>ABB?AB@B.9?88
@1OG
TTTAATGTGGATGCACCATGCCAGACCGTGGAAGATTTAACGAATGGGGTTGTGATGGCCCAGGTTCTTCAAAAGATAGATCCTGCATATTTTGATGAAA
+
CCCFFFFDHHHGHJFGJIJJJJIJJGHIBHIGIIEEHIJJIJJIJHJIJ@FHAHEIIGFHHGFF@DCEEEEEEEDBCDDDACDCDCDCDCDEECBDDECD
@1OH
GAGAGCTAGACAGACAATAGCTGAACAAGAAAGTAAACTTAATGAAGCACATAAGTCCCTTAGTACAGTGGAAGATTTGAAAGCTGAGATTGTTTCTGCAT
+
@@@DDDBDFAD<BFHFG>FGHEHBGCGG;CDEFEDAGGCFGGGIGEDGHEHGCEH??FHIIBGIGDHA8=ACDED=CC@AH=?>?@;?@>;@;>;>A;@C>
@1OI
TGCCTGTACAATGTCAGTGCCTATGATCAGAAGCCACAAGTGGGAATGAGGCCCTCCAACCCCCCCACACCATCCAGCACGCCAGTGTCCCCACTGCATC
+
@@@FADDDDH4AFCGDGAFHAFGGIHGIIIIIEHIIIIGHBFHIAGHIIBFHIECDCHE;FGGGECA@??=AACBACC99&029<:>:>AAACBCCCCCA
@1OJ
TGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTAT
+
CCCFFFFFHHHHHJJJJIHIJJJJJJJJJIJJJJJIGIJJJJJJJJJJJJJIJJJIIIIJIJHHFFFEDEEEEDDDDDDDDDDDDDDDDDDDDDDDACDD
@1OK
CGTCCATGTACAAGTACCCTTCTGACATCTCCTACATGCCTTCCTACCATGCCCACCAGCAGAAGGTGAACTTTGTCCCTCCCCATCCATCCTCCATGCCT
+
@@@BDFFFFDHHHECFHIIGGIJHIGGIGGHJJGJGIIIJJIJJGIIJIIJIIIIJJIGIJEHGGDCFHGGIJJHAEEHHFFFDCAEECCDDCCDCDDDDD
@1OL
CTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCT
+
@;=D=?AA:D<;A<AD@@?A@HEBFHIAD1*::?;?00:?:90900B;??=8==BFH=@CHIGII;7A7C62(9>8835@>;>C>5A;C:,,55(::4>>(
@1OM
TAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGC
+
CCCFFFFFHHHHHJJJIJJIJJJJJJJHGIJJJIJJJJJJIJJJJJJJJJJJHHHHHFFFEFFEEEEEEFDDDDDDDDDD:ACDDDDDBDDDDDDDDDDDD
@1ON
CAGAGTCAAAAATTACAGATTCAATTTCAGCAATTACAGGCTAGTGAAACTCTGAGAAACAGCACTCATAGTAGCACAGCTGCAGACTTACTACAAGCCA
+
C@CFFDDDHFHGGIGEAFHHGEHIIGGIHEIJIIDHGEHGGJGGIDIIDBGFFHCHGIIGICFCHDHGDGGCCAGADHFGFAADFDFDECEADCDD5=@?
@1OO
ATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCC
+
?;?DD:000<ACDE6E@<BD:CEBEEDEA@CDB8?*??@DE(6@A8866/;=6=?;).?3;@AAA@;838=?<??>88<A9>><>>::3>A4+98898+5
@1OP
CCAGAAGTCATCAGAATGCAAGATAAAAATCCATACAGCTTTCAGTCAGATGTATATGCATTTGGAATTGTTCTGTATGAATTGATGACTGGACAGTTACC
+
@CCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIIJIJJJJJJIJJJJJJJJJJJJJJJJJIJJIIHJIJJJIJJIGHHHHHFFFFDEEEEE
@1OQ
CACAAATTCGAGCATCACCTTCTCCCCAGCCCTCTTCACAACCTCTCCAAATACACAGACAAACTCCAGAAAGCAAGAATGCTACTCCCACCAAAAGCAT
+
C@CFFFFFHGHHHJJJJJJJJJJJJJIIJJJJJJJJJIJJJJJJJIJJJJJJJJIIIIJJJJIJJHHHHGFFFEFEDEEEDDCCDDDDBCBDDDDDDDDD
@1OR
TAAAAACATTATGACCAAAGTGCACGGCAAAAGATATGCTTACAAATTTGACTTCCACGGCATTGCCCAGGCTCTGCAGCCACATCCGACCGAGTCGTCC
+
?@@DBDDAA?F8?BB?EBFF,3C:FBFE@?CF>;:BDF>D<DDEECFF>FC9B=CF>AEFBEBE:EDDBDBC@6>;355>BBB?A:92<590998<@88?
@1OS
GCAGTGTGTTCACACTTTGTCAGATGAGAAATGGGATGTTATTAACTGGAGGAGGGAAAGACAGAAAAATAATTCTGTGGGATCATGATCTGAATCCTGA
+
@=@DDDAD;CDHHGGHHHGFIII>:FCFEDAEGGE>E=CEGEG>GDEBCF>D)?DHGGGHEIEGGEIHFFHEFEEED@D@B?CB@C;>CACC@C;>@:>A
@1OT
CTGATAAAGTATCTAAACTAGAAGGTCAAGTAGAATCTTATAAAAAGAAGCTAGAAGACCTTGGGGATTTAAGGCGGCAGGTTAAACTCTTAGAAGAGA
+
@?@BDDDDD<DDF@:CFGIHB<<CH:AA3CCFHH<FGIE?FEHGDFIHIG9<9DF?DDFG??CD(-;ADHHE>@EHB@>BBBCCCCCCCC>CA::@9??
@1OU
GTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCC
+
@BBFFFFFHHHHHJJJJJJJJJJJJJJIJJJJJJJJJJJJIJJJJJJJJIJJIJJIIIJIIJJJHHHHHFFDDDDDDDDADCEEFEFDDDDDDDDDDDDDD
@1OV
GTTGAATGTGACAGCACCTACACCTCAGCAGTTACAAGCCTTCAAAAATGAAGTAGGAGTACTCAGGAAAACACGACATGTGAATATCCTACTCTTCATGG
+
@@@FFFFFHHHHHIJIIJIJJJJJJJJJJJJJJJIJJIJJIJIGIJJJIJJIJHIJJIJHIGIGGGIJJJJIJGHFFDDE>CEEEEDEEEDDDDDDDEEDD
@1OW
GCTCAGCGTCGGCCACTCTGTCGGTCCGCTGAATGAAGTGCCCGCCCCTCTAAGCCCGGAGCCCGGCGCTTTCCCCGCAAGATGGACGGTTTCGCCGGC
+
<??DDFDDFHGHHIIEGBGAEAFHEHIGIGGBGHHIIIFEHIIIIHGFFCEEC>CCBCCBBBBBBC@BBBBBCCCCBB9@B<@@AACBB5?B><>B>@>
@1OX
AGTCAACCTCAATCTAGCACAGGGGGTGACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGCACCTGGGAGCTACCCCATGC
+
18+AD?=BD;2A<E>CB:F<?E3:CE?)?D4*8/B/8C(=A8;=).=@@).77==7;@7?@(;>>>>5>>;5>>:<<<?(558>><<>>5(:>9(2(333
@1OY
GAAGTACCTAGCTGCCACTCCATTTATATGAGGCAAGAAGGCTTCCTGGCTCATCCCAGCAGAACAGAAGGCTGTATGTTTGAAAAGGGCCCCAGGCAGTT
+
-(-(2)2<48<);19?@?5<@5>4<2=>=>8@@;??1=>?9?<:<7??<>?7>819;><1.<)6:?9>??8/=7=;);.9=?=>8(:;(3/7;/;<5/22(
@1OZ
ACTTGTGCCCAGCAATCAGGTGGTCGTACAAACTGCATCAGGAGATATGCAAACATATCAGATCCGAACTACACCTTCAGCTACTTCTCTGCCACAAACTG
+
CCCFFFFFHHHHHJJJJJJJFHIGIJGIIJJJJJJJJJJJJGJIIJJJJJJIJJJJJJJJJJJJIJJHHFFFFFEEEEEEDDDDDDCDDDDDDDDDDDDDD
@1P0
CCTCTCTCATCGGGAAGACCTGGCTTACATGAACCACATCATGGTCTCTGTCTCCCCGCCTGAAGAGCACGCCATGCCCATTGGGAGAATAGCAGACTGT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJGHHFFFFFEEDDDDDDDDDDDDDDDBDDDDDDDDDDDDDD
@1P1
CTCTGAGAAACAGCACTCATAGTAGCACAGCTGCAGACTTACTACAAGCCAAACAACAGATCCTCACTCATCAACAGCAGCTTGAAGAACAAGACCACTT
+
@@CFDFFDBFHDDGCFHGDECHE@BBHHEEG<EEEGIIEEHIGHGGII<6DH;BFGGG2==FHAGGEGGIIGE>AA2?DD@@CABE>CA?CC<CACCDDD
@1P2
TGCAAAAGGTGGCTGGAGAGAGATATGTCTACAAGTTTGTGTGTGATCCAGAAGCCCTTTTCTCCATGGCCTTTCCAGATAATCAGCGTCCACTGCTGA
+
@@BFDFFFGAFFBHHIFHHHGHGHIJIGIIIGIIHHHEIGG@GIIJIJGIEIJJJJJIIEGJIIJJJIIHHGFHFFFFEFEEECCEEDBBDBDDDDDDD
@1P3
CAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATAT
+
@CCFFFFFFDDHBGJJJEFHIIJJHEGEEGGGIIIGIIJIIGHJGHJIEHEBHBHHIIJJJJIGHHHFFFFCDFCCEECCCDDDBDADDCCD@CDDDED
@1P4
CGCTGGGCCTCCTGGGCACTGCCTGGAGGCTGATAGGACTTCAGAGGCTCTGCCCCTTTGTTGGCAGGGAGGCTTCCAGCCTGAGAGCACTCCCAGTTTGG
+
?1=?ADBDF1A:A:C1C?CE9CDG>8)?;1C@9BDFBBDE*?<?F*(-.=F<CFFFEEF>;??EA@D<6=8>,,;(:5(5<95,(:((+2>><<<4:A@:0
@1P5
CTTCATGAAGACCTCACAGTAAAAATAGGTGATTTTGGTCTAGCTACAGTGAAATCTCGATGGAGTGG
+
;1?DDB8:==DDFIFFIFIHCCHECFHC>CE9?F@GFE1*CAFFGFF@GBBD@DFFGIFFFGFBF)8;
@1P6
CAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATAT
+
CCCFFFFFHHHHHJJJJJJJJIJIIHIJJJJIJJJIJJJIJIJIJJJJJJJJJJJJJJJJJJJIHHHHFFFFEFEEDEEDDDDDDDDDDDDD@CEDEED
@1P7
GGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGT
+
CCCFFDBDHFFHDGIIIGGEAHICHHGHGGHG@F>DGE@DEGC=BHH;ADGGGEAHF=BFF6>=C>CDDDCCCC@CCBCD@ACDDDCDCDDDEDCCDC?BD
@1P8
ATGAGAGGGGGCAAAACATGTGTTGCAGACACACGGATTAAAGGCGGGGGACAAAGAAGTTGGCGGTGCTGCTCAACACTTCCTTGGGGTGCAGTTCATGT
+
(((-()2-(050(:8313939.2):7?<>(7))(('5''))))).:9'5&&)+2(((((((+(+0&&)&((+(+(+++2((+((((((&)&((((((((((
@1P9
GAAAAACAGGCCAGCTATGAACTATGATAAACTTAGCCGTTCACTCCGCTATTACTATGAGAAAGGAATTATGCAAAAGGTGGCTGGAGAGAGATATGTCT
+
??@DFDFFHDBFDEGBBBHEGCGHEHCDHGDEFEHIJGGJIJ@FHGEGGI6:CCGDHG@FFEGGGJHFHEADBBCFFDCD6;=AB==B?>??B<AADCEEE
@1PA
TTAGAAAAAGAAAAGAATGCTGTGTTAGACAGAATGGCTGAATCACAAGAAGCTGAATTAGAGAGGCTGAGAACACAGCTTCTATTTAGTCACGAAGA
+
@B@DDDFFGHFFHEHGIJEGHIHGHICHGGIIGJIJJIHGGGGGCDGEBGEHF<DHEEGIIIIGFGIIHGEEHFCCFFDEE@AACDDDA5;@@@DBB?
@1PB
GATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGC
+
@@@BDDBDHBFAFEGGAFF@GEGHIE;FE6EFGGC@CB?GIC<<F>CGC<CHGHHAHHFBB?ABA>ACA@CACCC:3,,5?AAB<?@@@?8??:>C:@<<
@1PC
CAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGAGACC
+
:??B?DD??DBD8++2C@FEI;;FE>EFIEDDEE?D91?D>DE@D<*8B?A6C@C;@A?C;C9;@;;6>;>(5>???,,:5=55><A?(9>::++4+(4:0
@1PD
GCCAAGGGAAGGACGTCCTATGTACCAACGCCAGATGTCTGAGCCAAACATCCCCTTCCCACCACAAGGCTTTAAGCAGGAGTACCACGACCCAGTGTATG
+
C@CFFFFFHGHHBHHIIJJIJJIJJJJJJJJJIJIJJJJGHGHJJJJIIJJIGIJJJHHHEFFFFDDEDDCDDDDDCCCDBDCCDDDDBDDDDDDDDDEEE
@1PE
GACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTG
+
CCCFFFFFHFHHFBHIJIIIGIJJJJJGIJJJJJJJJJIJJJJJJEGEEHGIJIJJJJHG?EHHBDEEFFEEDEEDDDDDDDDBBDDDDDDDDDDDDDDDD
@1PF
CGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTT
+
@@@DDFFFFHHHHJIJIIIGGHGGGGHIJJIEIIIEBGHGGGFHHGJIGIGIJIHJIIGHEEHFFFFFEEDEDB?C=C@CCDDDD89@@?BCCCAB@CCDC
@1PG
CCCCTCAACCCCTGTTTTCCCCTGCCTTCCTTGCAGAGGCCATGGAGGACGAGGAGAGACAGAAGAAGCTGGAGGCCGGCAAAGCCAAGCTTGCCCAGTTT
+
CCCFFFDFGFHFDGGHIJIIIJJEHIJJJGGJJIGHEHIGGGGHIIIEIJIBGIHHHHEEFEFECEEEDDDDDDBBDBB@BDDCDDDDDDDDDDDCCB:@C
@1PH
CTTAGCCGTTCACTCCGCTATTACTATGAGAAAGGAATTATGCAAAAGGTGGCTGGAGAGAGATATGTCTACAAGTTTGTGTGTGATCCAGAAGCCCTTTT
+
CCCFFFFFFHGHHIJJJJJJJJJJJJIJIJJIIJJIJIIJJGIIJJJJJBFGIJJJFHHGIIHHFHFHFFFFFFECCEEACDBDDDDEDDDDDDDDDDDDD
@1PI
GCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCC
+
1:+=:AD?A:AF:AAADB@EDCFBCGDBAH@C9:8?::?))?BF;?0(89?/*=.88)-'-5;;=;7=7).777>6>.6==(,;@:>A:>,:>:@;5:A:>
@1PJ
CTGATGAGCAAATTTAATCATCCCAACATTCTGAAGCAGCTTGGAGTTTGTCTGCTGAATGAACCCCAATACATTATCCTGGAACTGATGGAGGGAGG
+
@@@FFADDHGHFF>FGGHIIIGIGGCHIIGHH@HGIIIIIIIFG@GFHHCHHHGBAHGIGGIIIIIIIIIIGHFGCAEEDEFDEEECEEDDDDDD?;B
@1PK
AGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGG
+
;@7DDDDA8ACDHGFHGEEDEHEGHGDHHGGGHHG>;CCG?AHIIGC;FA=DAEE@ABDEEE@CCC3@3;,>A-;@>DC<CC@>CCCCCBC<?4>CC3:?8
@1PL
CCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCAC
+
CCCFFFFFHHHHGJJJJJJJJJJJJJJJJJJJJJIJJJJJJJIJJJJJJJJJJJJJJJJJJJIJJHHHHFFFF>CEEEEEDDDDEDDDDDDDDDDDDDDDD
@1PM
GTGCAGTGCTTAGCATTCTTGGGGAATGGAGATGTTCTTACTGGAGACTCAGGTGGAGTCATGCTTATATGGAGCAAAACTACTGTAGAG
+
:+:A<AAA+,?<?7??AB><33?C7?+<7*)?**1**1:1?*0?BB:ABBBB9*9A2=<>>B=ABB47;AB:72)6==).>7)6(..6>(
@1PN
GATGAGAGACCACTCTTTCCCCAAATTCTCGCCTCTATTGAGCTGCTGGCCCGCTCATTGCCAAAAATTCACCGCAGTGCATCAGAACCCTCCTTGAATCG
+
88=BDBDDAADFHGEEEHEFHG@HG+<CFHIIIIIIDDE?GHHGFHFGG=@GBE<BHAHECA=@;;?BC;6@@BBB@@CA@DCCCCACA@<BBCC@>>ACB
@1PO
CAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCAC
+
B@@DFFADHHHHHJIJJJJJJIJJJJJJJJJJIIGIIIJJIEIJGIJJJIGIIIJJHHHHFFFFEEEEDEDDDDDDCDDCDCDCDDDCCCCDDDDBBDDBB
@1PP
TGGAACGTCACATCAACGAGGAGGACACAGTGCCTCTTTCTCACTTTGATGAGAGCATGGCCTACATGCCGGAAGGGGGCTGCTGCAACCCCCACCCCTAC
+
CCCFFFFFHHHHHJJJJJJJIJJIIJJJJJHJJJJJJJJJJIJJJJJJIJIJ@HGIJJJJIIIHHHHFHFFDDDDDDDDDDDDDDDDDDDDDDDDDDDDDD
@1PQ
CTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAAC
+
@C@FFFFFGHHHFEGHIFGHIIJJJJIIGIJJJIIJEEHGIJIGIEHJJJFIIFGHGIIIIJIJIIJIIHEHHDFFFFDCECECCDDDDDCD@CCBDDDD
@1PR
GCACCTTGTTGGGATACGAGAGGCTACTCGGATAATTATAGGCGTAAACAGAAGGGGAATGGGGAGGGTGGCGACAGGTGGTCAGGACCAACAGCCTATG
+
7(088)94)2.((2))2-5((((((.)92:0((-9)0)0).))0-'((/.6)))(''-'(.).(('3',,2()&&&)(++6&+(+(((++(((((((+(+
@1PS
CGACAAATCACCGGCCTTCTCCTGACCCCGAGCAGCGGCCCCTCCGGTCCCCCCTGGACAACATGATCCGCCGCCTCTCCCCGGCTGAGAGAGCTCAGGG
+
@C@FDFDDHHHGFJEIIIJGHH<CGEHGHBHEEHGGIEHIHEGFB<<BBBBBDDBDDDBDBDB?CCDDD@BDBDDDBCACDD<<50>?AC@<@A:CCDAB
@1PT
CCGGAGAACCTGAGACACCTTAAGAACACCATGGAGACCATAGACTGGAAGGTCTTTGAGAGCTGGATGCACCATTGGCTCCTGTTTGAAATGAGCAGGC
+
@@@FAFFFFHGFFDCGEHFGHGGFGIGGIJJFIJHCGGGIJJJIJFIIIGGGBFHJIIJIGICHHFHEFFFFF@CCEEDCCD>@@CCDDDDACCDCDDDD
@1PU
CCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAAC
+
CCCFFFFFGHHHHIHIJJIJIJJJJJJJJJJJJJJIJJJJJJIJIJIJJJJIJJIJIJIJJJJJDHHHFFFFFEEEEEEEDDCDDDCDDDCDDDDDDDDD
@1PV
CCTGTTTGCGGAAGAAAAGGAAACCTCAAGCTGAGAAAGTTGATGTGATTGCCGGCTCCTCCAAGATGAAGGGCTTCTCGTCCTCAGAGTCGGAGAGCTCC
+
@@?DDEDDDHFFHGIIIG@DGIIGAFB@BFCHAH3?DDFGHCHD>/?FHG<=B;FE<BACFFFFDECEEC>A?BABDDDD?BDDCD>>>4>BB59&<?CC@
@1PW
GTAAGCTCTTTATTAGATGGAGTTGTGACTATGACAAGCAGGGGTGCTGAAGGATCAGTTTCTAAAGTAAATAAAAGTTTTGGTGAAGAATCAAAAATAAT
+
CB@FFFFFHHHHHJJJIJJJGIFHJHIJJJJJJJJJJJIJJJJJ@FHGJJJJJJJJJJIJJJJJJJJEEHHGHHHFFBFFFED?BDDDDDDDDDDDDDDDD
@1PX
CTCTATACACACACAGCCGGAGGTCATACTGCATCAGAACCATGAAGAAGATAACTGTGTCCAGAGGACCCCCAGGCCATCCGTGGATAATGTGCACCAT
+
@C@DFFFFHFHHGGECFECFHFHDGGIIGIIIIIIGE@?FHGHIJIJJJGGIIJJIIEHHHHHFFEB?BCDDDDB?BD@CDDB??>?CDDCCDACECDDD
@1PY
CTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTC
+
CCCFFFFFHHGHGJJJGJIGHHJJHIJJJJJJIJGIIJJIIJJJJIJJJJJJIJJIJJJJJJIIIJHHHFFDDDDDDDDDDDDDDD@DDDDDDDCEDDDDD
@1PZ
CCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTAT
+
CCCFFFFFHHHHHJJJJJJJJJJJIJJJJJIJJJHIIJJJIJJJIJJJJJJHHGFFFFFEEEEEDDDEDDDDDDDDDDDDDDDDDDEDDDDDDDDDDDDDD
@1Q0
TCGACTTTGAGACCCTGAAGCCGTCCACACTGCGTGAGCTGGAGCGCTATGTCACCTCCTGTTTGCGGAAGAAAAGGAAACCTCAAGCTGAGAAAGTTGAT
+
@@CFFFFFHHHHHIJJJJJGIJIJIJJJIJJIJJIJJJJJIIHJJJGIJJJGHGHEHGFFFEFEEEDDDDDDDDDDDDDDDDDDDDDDDDCBCDDD@CDDD
@1Q1
GCCAATTTACTGGAGCAGGGATGACGTAGCCCAGTGGCTCAAGTGGGCTGAAAATGAGTTTTCTTTAAGGCCAATTGACAGCAACACGTTTGAAATGAATG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJIJJJIHIIIJIJIJBGIJIJJJIJJIJIICFEHIJJJHHHHGFFFFFEDEEECDDBBBDBBCDDDDDDDDED
@1Q2
CATCCCCTTCCCACCACAAGGCTTTAAGCAGGAGTACCACGACCCAGTGTATGAACACAACACCATGGTTGGCAGTGCGGCCAGCCAAAGCTTTCCCCCTC
+
CCCFFFFFHGHHGGJJJJJJJJJJJJJJJJJJIJBFHIGIJJJJJJJHIGGIJIJJJJJHHHHFFFFE@CDDDDDCDDDDDDDDDDDDDDDDDDDDDDDDD
@1Q3
CAAGATGCTTGTGGCTGTGAAGGCCCTGAAGGATCCCACCCTGGCTGCCCGGAAGGATTTCCAGAGGGAGGCCGAACTGCCCACCAACCTGCAGCATGAGC
+
@@@?AABDFF>:ABFE=F;,AAC;@EA;EB?*???DF<DFD8?B9/?DFFEFA'-?(7)=7;;;;??>>>/?B82'&24((+(8<<??5(+89?:(+4::(
@1Q4
CACTAACAAGAAAACAGGGAATTTTTGGGAAATATGAAAAGCCAAAATTTGTGCAGTGTTTAGCATTCTTGGGGAATGGAGATGTTCTTACTGGAGACTC
+
@@@DAEDBFHGDDCEBFHI?EHGIIHIIGEHGEGIGECHEDEHIIIGGGGC=CFHICHFHIIEGIGIEAEFFGFBD>A@>C?>CACEDCCCCCCCCCBCC
@1Q5
CCATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACC
+
CCCFDFFFFHHGFIJHGIJJJJJJJIIJJIIIIJIIJJJJIJJGJIJGJJJHHHFFFFEEEDEEEDDDDDDDDDDDDDDBDDDDDADDDDDEDDDDDDDDD
@1Q6
CTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGC
+
CCCFFFFFHHGHHJJJJIIIJIJJIJJJJJJIJJJJIJJJIHIJJJHIJIJJJJJJIJJJIIIIIHHHHFDEEFFECECEEEDDDDDBBDDDDDDDDDDD
@1Q7
TGAAGACAGACATGGAACGTCACATCAACGAGGAGGACACAGTGCCTCTTTCTCACTTTGATGAGAGCATGGCCTACATGCCGGAAGGGGGCTGCTGCAAC
+
??<BDDDDFF;?BDE@CEEEFHIEHGCB@HE@GGGEDCAHID??B8CFHGCGICHC;@=CC@G@>>EE;>CB;6@>ACACCC>?B?BBB@B7@B<ACCCCC
@1Q8
CTTTTCTCCATGGCCTTTCCAGATAATCAGCGTCCACTGCTGAAGACAGACATGGAACGTCACATCAACGAGGAGGACACAGTGCCTCTTTCTCACTTTG
+
CCCFFFFFGFBFHHGGIJJJJEIJJHGJIHJIIIIIJII@GFAHIIGIJIIJJIIIGIJGIGIGGHDHFEHFDCDDBB?ACDDDDDDDDDDDDDDCDDDC
@1Q9
AGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACT
+
CCCFFFDFHHHHHIIIJJJIJJIJIIJIIIIJJJJJJJJJJJJJJIJIJIJHHHHHFFFFFEEDDDDDDDDDDDDDDDDBCDEDDDDDDDDDDDDDDDDDD
@1QA
CTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGC
+
CCCFFFFFFHDFHEGHGFIGGIJJJIGEIIIGJJGHIIGJIJFIHIGGGHGICFHI)=CHHDHGGFHHFDCDDCDCCCCEECDDA??BDDCCDDDDDDDD
@1QB
GAGAGACCACTCTTTCCCCAAATTCTCGCCTCTATTGAGCTGCTGGCCCGCTCATTGCCAAAAATTCACCGCAGTGCATCAGAACCCTCCTTGAATCGGGC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJIJIJJJIJHHHHHFFFFFCEEDDDDDDDDEDDDDDDDDDDDDDDDDDDDDDD
@1QC
CATCAACCAAGAAGGAGAATATATTAAAATGTTTATGCGCGGTCGGCCAATTACCATGTTCATTCCTTCCGATGTTGACAACTATGATGACATCAGAACGG
+
@@@FFDFFHFHAFGIFGIGHIIJJJIIJJJIEHIGHHIIGIJFDAEHIICAHHHEHEFEFDFFF@CCEEEDDDBACCDDDDBCCCDCCCDDCDCCDCDCDD
@1QD
AGATCATCGAAATCAATTTGGGCAACGAGACCGATCCTCATCAGCTCCCAATGTGCATATAAACACAATAGAACCTGTCAATATTGATGACTTGATTAG
+
CCCFFFFFHHHHHJJIJJJIJJIIIJJIJIJJJFHJJJJJJJJJJJJJJJJJH?EHHHHFFFFFFDDDEEDDDDDDDDDDEEEDEEDEDEDDDDDDDED
@1QE
AGCATTCTTGGGGAATGGAGATGTTCTTACTGGAGACTCAGGTGGAGTCATGCTTATATGGAGCAAAACTACTGTAGAGCCCACACCTGGGAAAGGACCT
+
CCCFFFFFHHHHHIJJJJJJJIJJJJJJJJJJIJJIJJJJJJDHIGJCGIIJGIIIJIJJIIJGIIJIJIHHHHEHHFFFFFDCDDDDDDDDDDDDDBDD
@1QF
GATCCGAACTACACCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATGACATCTCCTGTGACTCTCACCTCTCAGACAACTAAGACAGATGACCCCCAAT
+
=+=A+?+7A?7?B;AAAABBCA7AB<7?ABB<A=7=3??AB:=A9==?BAA7AB<>>BB7===>A>.7).=5>=>=;;;>26;>9;55;;;5=59=8'808
@1QG
GCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTAT
+
@CCDDDDFFHGDBEGHIGIDEHIIBFDHAAFFGGHEIA=??FFEBDG?FGGHIIBFHGE>FEGGAEEGC>=CBHEF@BD@CECCCCB?>?BCCCBC>ACCC
@1QH
CTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTTATGGGC
+
@@@DD33BFBAADFFGED<CBB<F4CC9FDE;?D;FG9CG9D;??DF6@FEAFE@;E=C7@AEFECEDC8?@@??5<@BBB,>@A(::@8>098<@@:>8?
@1QI
AGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAAC
+
@@@FFBDFAFHDD>EB>A@CHHHHGEHGI@@EGH>HGIEGH@DH>GHIHIHG:AEEACGIII>C@ECHBA;@7?>?@CA@AC>ABCCCACBCCCCAABCB<
@1QJ
CCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAAC
+
CCCFFFFFGGBHHJJJJHIJJJJJIGJJJJJIJJIJIJJJJJJGHGIGDHGHIIIIGJIGIJJIGIIIIFHFGFFFDFECCCEECDDCDDDDDDCDDCDDC
@1QK
CTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTC
+
CC@DFDDDHGHHHJJGEEHHGGEGGIJJHGGGIJJHICGHIIGGHAGIEGIGIIIJIIGGIJIICAHGIGGFHGFFFFFEECEEEDCDDDD@BDABDCDDC
@1QL
GGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJIJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJHHHHHFFFFFFEEDDDDDDDDDDDDEDDDDDDD
@1QM
CCCCCAGCCAGTGCCTTGGATATTTCTGGGGGGACTGGACTGGGGCCCCTGGGCCAGCTTTCAGGAGAAAGGGAAGGCGCCACCCGGGGTGGGGGGGAAGG
+
00(-((29(=(98<))<4..6:1).;)29:83:-72:68(++((0&070(+8<(22(((((((((+++(++6:/+8-(&&&)&+&&050)0&5&)&)&&+(
@1QN
AGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATG
+
@@<DDDDDHD?FBHFHGGIIII8F?CC9D;DHIGIHGEGHGIAG<CHCHGDFHGEHCCACEHF@DD3;.>;=AB:,5<ACC>?B1882?A<?CCCC:@C>C
@1QO
CTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCAC
+
CCCFFFFFHHHHHJJJJJJIJJJJJJJJJJJJJJJIJJJJJJJJGHEIJIJHHHHADFFFFFEEEEEEEDDDDDDDDDDDDFDDDDDD
@1QP
CACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGAT
+
C@@FFFFAFHHHHHEGIJGHGIJGGIIIJJIJGEGIHHEGDIGIGB@FHGHGI>FHGGE:CHHGGCB?DEEDEEDDDDDDDCDDDCDDDDDDDDD?>CCA@
@1QQ
ATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCC
+
@@@FDDEDHHDFHGGIGGIHIIJJJJIGGHJGIIIJGGEFHGHEHGJJJIJJGIHJJJJJGIIGEIGHAHFHGEEFFDFFEEEDACCDCDDDDDCCDCADB
@1QR
TACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJGIJJJJJJJJIIIIJJJJJJJIJJIJJJJHHGHFFFFFFEDEDDDDBDDDDDDDDDDDDDDD
@1QS
AAGCAAGAAGAGAAAAGGATGAGACAATGAGAGAATTTTTAGAGTTGACAGAACAGAGTCAAAAATTACAGATTCAATTTCAGCAATTACAGGCTAGTGA
+
C@CFFFFDFHHGHIIIGIJGHIEHIJIIGGGIJGICHJIIIJHHDHIJJJIJJGIGIIFEHIGGIIIJFIEHEHHGHHFFFFFFFCCEEEECABBC?>CC
@1QT
GAAAGCAAGAATGCTACTCCCACCAAAAGCATAAAACGACCATCACCAGCTGAAAAGTCACATAATTCTTGGGAAAATTCAGATGATAGCCGTAATAAATT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJIJIJJJJJJIJEHIIJHHHHHHHFFFFFEDEEEDDDDDDDFEDDDDDDDDEDDEE
@1QU
GAGGAGAAGCAGGAGCTGTCGGGAAGATCAGAAGCCAGTCATGGATGACCAGCGCGACCTTATCTCCAACAATGAGCAACTGCCCATGCTGGGCCGGCGCC
+
@?@DDDADHDDFHECD;C?FGFD@?D;CFIICH@@DBDHGIIGI?4B=BFHI;@;A9=ABCCA@5ACCCCBBACC@AC?A>ACC8ACC>@CCB2?9@BB.5
@1QV
CACAGACCTCTGATGGACAGCAGATACTTGTGCCCAGCAATCAGGTGGTCGTACAAACTGCATCAGGAGATATGCAAACATATCAGATCCGAACTACACCT
+
CCCFFFFFHHGHHIJJJJJJJJJJJJIJJJHJIJJIJJJIJJJJJFHIHIIGIJJJJIIIJIJJJIJHHHHFFFFFFFEEDEECEEDDDDDDDDDDDDDDD
@1QW
TGGTCTATTCTGCTCAAATGTGTAGTGTTTTCAATTTAAATATTTCTTATATATACCAGCTGGTTTATTTCCCTGAGCTGGCCCCCAGGTTCTAGGAGAA
+
((0((:)46))))2))..).).):)))39)2))2)))29))))).3)9)).:9<1))6=().)06()..))))..).<80)57.'''9=(((.(--((,7
@1QX
CTTTGAGAGCTGGATGCACCATTGGCTCCTGTTTGAAATGAGCAGGCACTCCTTGGAGCAAAAGCCCACTGACGCTCCACCGAAAGATGATTTTTGGATAC
+
@@@?DB;DF;AFFFDBEBIGI>ACA>FGGHIFHGGEB@CB@FHFCH@@BGHIGCHIIIFGDGGCADHFHCHD><8>A@>?B@B?B8C3>C>CDCCBBCCDA
@1QY
CCCAGCAGAACAAACCAAAGAAAAAGGAGAAAGACAAGAAGGAAAAGAAAAAAGAAAAGCACAAAAGGAAAGAGGAAGTGGAAGAGAATAAAAAAAGCAA
+
@@<ADDD;+<CFDCFD;<+<C;99F@B@3???CFFADBFF@;D@*93CF)8.5;@E>>C(.;;BA?CC(;>;>?<<?@5:@(,,2<@>:4>@:>5<<((+
@1QZ
CTTCCACGGCATTGCCCAGGCTCTGCAGCCACATCCGACCGAGTCGTCCATGTACAAGTACCCTTCTGACATCTCCTACATGCCTTCCTACCATGCCCACC
+
@@@DDDDDFHF:?FGD<CB;EBCGGHIEHEGHGGIH>GGIDAEHH8(;A?C@BEE@C@C@CCCC;C@5(>5@@5>CCCCCCCCCCCCCCCCBC>ACCCC?B
@1R0
CGTCAGAGTGTGGGATTCTGTTACTCTATCCACACTGCAGATTATTGGACTTGGCACTTTTGAGCGTGGAGTAGGATGCCTGGATTTTTCAAAAGCAGATT
+
@@BFFFFFDFFHHJHIIJJJJJJJJJJJJIJJJJJJGHJJGIJGIIIIIHGIJIIJIJJJJIHIIIBGHEEABDEDEDCDDEDDCDDDDCDDDDDDDDCCD
@1R1
AGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACT
+
???=;BA;3CA<CBB22<<)1<8C;)1?*?*?<9D2D298BB@D>)88B/)=@48.@)))=?D:.==;;)'(;(65>????9<A:>>>A>>42)5>?<?8>
@1R2
CTCAGACAAGAAGAAAAAGAAAAGGGTACACTTGAACAAGAAGTTCAAGAATTACAACTTAAAACAGAATTGTTAGAAAAACAGATGAAGGAAAAAGAGA
+
CCCFFFFFFHFFHGIJJJJJJJJIIJ?EGHGIIJJJIJIIJJJGHHGHIJJJJJJIJIIJJJJJIJIJJHHHHHFGFFFFFDDDDEDDDDDBDDDDDDCD
@1R3
GAAACTCTATACACACACAGCCGGAGGTCATACTGCATCAGAACCATGAAGAAGATAACTGTGTCCAGAGGACCCCCAGGCCATCCGTGGATAATGTGCAC
+
@@@D?>DDFDFFFEF6E@BC?+CGIFI;BGDGA@DBB<?DFBFECF=CE==@@@@@DD@;=?AE=EED@DD@;=C?;>B<9<BBBBB2<@7:4>>>:>4>:
@1R4
TTTTGATTTTGGTTCTCCAATTTAGTCCATTTTATTGCTAAAATACAAAAGTTCATGTATGAAGTTCTTGCATTCGTTTTTTTTTGGAGCAGGCATATGGG
+
CCCFFDFFHHGHHIJJJJJJJJJIJHHJJJJJJJIJJJJIJJJJJJJIJJJEHIIIIIIJJJJIIIHHIJJJIJIIIGJJJFDDDBB@CCDDDDDDDDEDD
@1R5
CAAGCACGCAACTATCTATAGACATAGCCATGGCCATACCCATATGATCGGGCGAATTAATTTGAGGGTCTCGCTCTAATTTGAAAAATGCCCTAGCCCAC
+
000(-()-(((0;))2)22.))2)))))2..8)=.=<1)=>))00)0).0'--'5==/)6(3((((,(((,82272;53((((++3(28(+((+2(+(2(+
@1R6
CAAATTCGAGCATCACCTTCTCCCCAGCCCTCTTCACAACCTCTCCAAATACACAGACAAACTCCAGAAAGCAAGAATGCTACTCCCACCAAAAGCATAA
+
@C@FFFFFHGHGHJJGHGGIGIJJJJIJJJIJJJJJIIIIJJIGGJJJIIIIIIJJJJJGGIIJIGFHHHEFFFFEDEDCECDDDDDDDDDDDDDDDDDD
@1R7
CACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACC
+
CCCFFFEFHHHHHJJJIJJJJJJJJJJJJJIJJJJJJJJJJJJJJHIJJIJJJJIJJJJJJJJJJIHHHHHFFFDDDDDBDDCDCDDEDFEFDDDDDDDDD
@1R8
AAGAAAGTAAGCAAGAACAGTTGATTTTGGATCACTTACCATCTGTAACAAAGGAATCATCACTTAGAGCAACTCAACCAAGTGAAAATGATAAACTTC
+
CCCFFFFDFFFHHJJJIJIJJJJJJJJJHIIGIIJIJIIJJJGGIHIJEIJJIJIJJEGHGIGGIIJGIDIIDHIIFEHHFF@CDEEE>CEECDDDDDC
@1R9
CCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACA
+
CCCFFFFFHHGHHJJJJJJJIJJJIJJJJJJJJJIIJJJJJJJJJJJJJJJJJJIJJJJJJJJJHHFFDEEEDDDDDDDDDDDDDDDDDDEDDDACDDDD
@1RA
CTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGC
+
@C@FFFFFGFFHHJJJJJIJJJIGIIIJIIJJJBGIIJIGHFHIIIJIIGIJIGGIIJ@FHGIIJJJIIHHHHGDFFFFEDEDDDDDDDDDDBBBDDDDD
@1RB
GAAACTGATATAGTACAACGAATGGAACAAGAAACACAAAGAAAGTTAGAACAACTCCGGGCAGAGCTGGATGAGATGTATGGGCAGCAGATAGTGCAAAT
+
CCCFFFFFGHHHHJJGIJIHIJIIGHIJIJJJJJJJJJJIIFFHIFGHFHIGGIGIJJJJIIFHEHFFFFBEECEDCC;AFEDDDCDDDDDDDD>ACDDDD
@1RC
CTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGC
+
CCCFFFFFHHHHHIJJJIJJJJJJJIJIIJJJJIIGIJJJJIHJIIIGIIJGIFIJJIJIJJJJIHHHHFFCBDFDEEEDDDDDCBDDBDDDDDDCDDDD
@1RD
CACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGAC
+
@C@FFFFFGHHHDEGHIJJJGBHHJGIGEGGGHEGIIJIJJIIIGGIE?FGCGGIGIGGIJJIFIIIEEHEEBFFEE?BEDDBBBDDCDDDACACCDDCDD
@1RE
CAGGAACCCAGAGATTTTGCATATGACTCAGAAGTGCCTAGCTGCCACTCCATTTATATGAGGCAAGAAGGCTTCCTGGCTCATCCCAGCAGAACAGAAGG
+
CC@FFFFFHHHHHHJJJJJJJJJJJJJJJJJJJIGHIJJIIJJJJJJJJJJIJJJJJJJIJIJGJJJJJJJJHHHHHFFFFFEDEEDDDDDDDDDDDDDDD
@1RF
CATCAGAATGCAAGATAAAAATCCATACAGCTTTCAGTCAGATGTATATGCATTTGGAATTGTTCTGTATGAATTGATGACTGGACAGTTACCTTATTCA
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJHIIJJJJJJJJJJJJIJJJJJJJGIJJJJJJJJJIJJJJJHHHHHFFFFFFEEEEE
@1RG
CTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGC
+
???DDDD3CDDBA+?CEEBFFCFD?EB93C9ECDDD@DD><DC;D;@DDA<B7=A@DA;A:AE==CC=ADDDADD@3@A>>A=>??>AA:3,5<=???>?>
@1RH
CCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTAT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJIJJJJJJJFIIJJJJJIJGHJJJJJHHHFFFFFEEEEEDDDEDDDDDDDDDDDDDDDDDDEDDCDDDDDDCDDDD
@1RI
CAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGG
+
@@@FFFFFHHH?FGGGCGIIHEHADGHIIEFHHBHGEGGGGI@?FFDGGBDFDBF@@BFFHDBGGAHIIECEHBEDFEEEDEECDDD>;<A?BB<9@B@C?
@1RJ
GCATATTAGTCAGCGGCGGAGAAGAAACTAACCAGGATTCCCTCAGTAACGGCGAGTGAACAGGGAAGAGCGCCGAGTAGGGAAAGCGAGTAGGTGATGGT
+
;3(@@@@8..=@4.>/(1-=('.<.9:3>))..<35...)..;)9=....,';5;:&((+(8(6((+((+(&&&)&)+2((28+8((&()0(2((+((+22
@1RK
CCAACAGGCTTGCAGCCAATTTACTGGAGCAGGGATGACGTAGCCCAGTGGCTCAAGTGGGCTGAAAATGAGTTTTCTTTAAGGCCAATTGACAGCAACAC
+
CCCFFFFFHHHHHJJJJJJJJJJIJJJIIIIIIJIJIJIIGHGIJJJJFIIIIJJIGEGIJHHHHFFFFFDEADEEEEDDDDDDDDDDDDCDCCDDDDDDD
@1RL
CATACAGCTTTCAGTCAGATGTATATGCATTTGGAATTGTTCTGTATGAATTGATGACTGGACAGTTACCTTATTCAAACATCAACAACAGGGACCAGAT
+
@@CDADEDHHHGFH?FHGIIIHIIGIIIIIIIIIIIIIIHEHIHBGHIICFGGIGEAHHHIICHEHGHIGGDHIIIIIIIGIGGIGHGHFBEEC;AABBC
@1RM
CCTGACCCCGAGCAGCGGCCCCTCCGGTCCCCCCTGGACAACATGATCCGCCGCCTCTCCCCGGCTGAGAGAGCTCAGGGACCCAGGCCGCACCAGGAGA
+
CC@DDFFFHHGDHIIIGGIIJJHIIJIFHGGIIHHFFEFEDB?CD>;AC?@BBBDDDCDDD@BDDDDBDCC@@ACDDDDDDDD@BDDDDBDD>@?ABBD<
@1RN
CACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCA
+
C@@FFFFFHHHHHIJJJJJJJJJIIJIIJJJIIJJJJIIIJJIIJJIJJJJJJJJJJJJJHGHHHHFFFFFFEEEACBCDDDDDDDDDDDCDDEDDDDDC
@1RO
CCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGC
+
CCCFFFDEHHGHHJJJJJJJJJJJJJJJJJJIJIJJIJJJJJJJJJIIJJJJJJJJJJJJJJJJIHHHHGHFFFFFFEEEDDDDDDDDDEEEDDEDEDDDD
@1RP
AGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGAC
+
@@=DDDDDHHDHHIGGIIHGIICEHHHIDGIIIIHHIHGGCG>FHIIIIGHGHIIIIGGIEGGECHGIEHF;BBEEE@ACC;ACCC@CCCCACCCB???@B
@1RQ
GAAAGATTGATTTTCTTAGACTCCATTAAGTCCAAATCCAAAGACTCTGTGTGGGAAAAAGAAATAGAAATACTTATAGAGGAAAATGAGGACCTCAAAC
+
CC@FFFFFHHHHHJGGHHGEGHIJIGJJJJHIEHIGIJIIJGGEGIIIFBFBDHDEHIJGIDHGHJIGIIEGGIIEEHECHFFFFCCCCEECBDDDDDDD
@1RR
TAGAGAGGCTGAGAACACAGCTTCTATTTAGTCACGAAGAAGAGCTTTCCAAACTGAAGGAAGATTTAGAAATTGAACATCGAATAAATATTGAAAAACTT
+
@@@DDDDDD?FHHGG>?ECC3AFG>@B9C9EHIH@BCFG<;B*?99?>F>D=BHGI3)=@AEDEGHGE;;A=?;@@BD;>>?AACBCADACBC@CCAA25@
@1RS
CTCAAAAAGAAAAGAGATGAGAGACCACTCTTTCCCCAAATTCTCGCCTCTATTGAGCTGCTGGCCCGCTCATTGCCAAAAATTCACCGCAGTGCATC
+
@@@DFFFFDHGGDEEFHHEIFGG=G?HHI?FGIIIIGIGIIGCHIIGIIHIIIFIHIGEIG@AEFEEDFDDDDECCC>A?ADBD>>@CBBDDBCACDD
@1RT
CTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTT
+
CCCFFFFFHHHHHJJJJJJJJJJJJHIJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJIHEHHHHFFFFFFDDDDDDDDDDDDDDDCDDDDEDDD9<9B
@1RU
TGATGATTGGGAGATTCCTGATGGGCAGATTACAGTGGGACAAAGAATTGGATCTGGATCATTTGGAACAGTCTACAAGGGAAAGTGGCATGGTGATGTGG
+
@@?DFFFDFGHDHIIGJGGGFFEGE;BFHEHGIGHGHIIIJJCDEGIIGHHBGHGGG<FHGGHCHHDCDEHHEHHHHDDEF?@?C;@CDCDBB:@>@C@>A
@1RV
GTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGC
+
;??D=B:BD>DDDDEB:2CFE+A:<:?AEB9F*1:9EE<C3CDDDDI0?:-8BEDC==AAEC>;?AC7;?A;@DA;(;>@>;??A?A?<A:>::<9???
@1RW
GAGGCCCTCCAACCCCCCCACACCATCCAGCACGCCAGTGTCCCCACTGCATCATGCATCTCCAAACTCAACTCATACACCGAAACCTGACCGGGCCTTCC
+
@<<BBD7DFBDFACEG8GH@GBFGGIIC<CEA@'@FHE7?7??=BD9;A@;>@CCCCC>@;>CAACA@C@C?CCC@@@C>9<5@BBBCBCCABB<@<<ACC
@1RX
CTGTAACAAAGGAATCATCACTTAGAGCAACTCAACCAAGTGAAAATGATAAACTTCAGAAAGAACTCAATGTACTTAAATCAGAACAGAATGATTTAAGG
+
@@CDFFFFHHHHGJJJJJJJJJIJJIIJJJJJJJJJJJJJHIIIJJIIIJJJJIJJJJIIIJJIJJJJJJIJJJJJJGHHHHHHFFEFFEEEEEEEEDEDD
@1RY
CCCAAGCCTGTGAGCAAGATGCGCATGGCCACCCCGCTGCTGATGCAGGCGCTGCCCATGGGAGCCCTGCCCCAGGGGCCCATGCAGAATGCCACCAAGT
+
CCCFFFFFHHHHGIJJJJIJJJJIJJJJIIJJJJJJGJJIIIJJJJJJJJHHHFFEDEEEDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDD>
@1RZ
GGGAGACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTT
+
@@@DDDDFHHHHHJJIIHIFIIHGHJGHIFHIIIJGHEGIJIIJIGHEEFFDDDDDDCDDDEDDDDDDEDDDDDDDDCDDDDDDDDBDDDDBDDDDBCCED
@1S0
ATTAGATGGAGTTGTGACTATGACAAGCAGGGGTGCTGAAGGATCAGTTTCTAAAGTAAATAAAAGTTTTGGTGAAGAATCAAAAATAATGGTGGAAGAT
+
C@CFFFFFHFHBFEGHIIBCEHGDHGGGGGGIDDGHGIIG9?B>AFGFHGBFHECGCFIIIEDHHI@DECHGBFFF@AAA6>CDC?ACCDDD:>??C:5@
@1S1
CTGTCATTCACCCTCAATTTCTGGCAGATCTGCTGTCCCCAGAAAAACAGAGAGATCCCTTGGCCTTAATTGAGGAGCTAGAGCAAGAAGAAGGACTCACT
+
@@CFFFFFFHHGHIJIJJJIIIGGGJJJJJJJJIIGIJJJIIGHJGGAFHEGIIFHHIHIJIIIJGIJJHHGGHHDFDFCCCECEDDCCDDDDDBDDDDDC
@1S2
AAAGGACCTAAAGGTGTATATCAAATCAGCAAACAAATCAAAGCTCATGATGGCAGTGTGTTCACACTTTGTCAGATGAGAAATGGGATGTTATTAACTGG
+
CC@FFFFFHHHFHJAFEGHJIIIIIJJJIIJJGJJJJJIJJJIJIJIJIIGHIJIJBFBFHJGGGEIIIJIDGIJGHGHHHFFFFFFECDCCDEDEEDDDD
@1S3
GTCCCAGAAAAATTCGATGGAGACATCAAACAAGAGCCAGGAATGTATCGGGAAGGACCCACATACCAACGGCGAGGATCACTTCAGCTCTGGCAGTTTTT
+
@@BFFFFFHHHGGJIJJIIIGIJJJJJJJJJJJGIJJJJJJJJJJGIIJJJJIIIGIIIIGHHFFEFFFDDDDDBDBBCDDDDDDCDCDDDDDDDBACDDD
@1S4
ACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCCGCAGCCACTGCACCTACAAGACC
+
?@;:ADD?:0C;FGF?F=DG@AFI@@?911:?DGB?G>GGE9?<?DF<@B)?;BC=<=D=CECFEFE@2=?9;6;@C(,,33=B9<ABB:>BB>ABAB<?<
@1S5
ATGGATCAGCATTTTATTGCAGTGATAACAAATGTTTGAATAGTGAGAGAAGACGAAATGGAAAAAGGTAAACTTGGACAAGGAGATCAAGAGGTACGACT
+
0(-(()=(.@)))).)).<)9))))))3)))<)..:)1)):))..)):)(.):)(7(<()<))8>(-9=).)8)<8));=(9.(((-(7--(((,((','&
@1S6
ACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGG
+
@@CFFFD?DCFFBEFHEGGHJIIICDGGIICEFHHGBFGHEGHDHGEFGGHIJGAHIHHHFFCCDDB@?CACCCBACCCCCCCCDBBD?DDDDDDBCCCDD
@1S7
GTTCTGTGTGCTATTGGTGTTTATTTGCATCCACCTGTCCAGTTGCTCTGCTGTCTTGTGTTTTTGCAGCCTCTACAACCCCACGTCAGAGTGTGGGATTC
+
@@@DDDDDHD?F4AFHI<FCEHHIGGIIIIIEIIEHDA@FGIHGIGE<GGICFFBFHG@GCHGIGI=HEGIIIGHFFHBDEBCCCABBBAC:@(:@BACCA
@1S8
ACTTAAAGATAATTTAGGCATTCACTATAAACAGCAGATAGATGGTTTACAGAATGAAATGAGTCAAAAGATAGAAACCATGCAGTTTGAAAAGGACAATT
+
@C@DDFF?FFDFDDGIGEGHGIIIIIIIIIHHGG;FHIIIGCDGGBGHIIIGIICHHIIGGFBHGGGHIIGGIIEHGIICHCHHFFFD>DDECECEDDD>C
@1S9
CGGACGGTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCG
+
@@@DAD1@?FFF<?ACF??@?F@:B?FD=G?FF@F=B<C6AB4AEF>8<B>BC>6>A>@A@A:3:><<<:>?A9ABBB59@88>B<8?BB@@@BBA@AAB3
@1SA
TTCACTAACAAGAAAACAGGGAATTTTTGGGAAATATGAAAAGCCAAAATTTGTGCAGTGTTTAGCATTCTTGGGGAATGGAGATGTTCTTACTGGAGACT
+
C@CFFFFFHHGGGJJJIJJIIIJJJJIJGIIIGIIJJIJJJIJIJJJJJJJJIFGIIJCHCHGIJIJJJFHHHHFFBCEDEEDDDDDDEEDDDDDDDDDDC
@1SB
GCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGG
+
CCCFFFFFFHHHHJJJJJJJJJJJIJIIJJJJJJJJJJJJJJJIJIJJJJIJJIJJJJHHHHHHFFFFFEDDDD?BDDDDDDDDDDDDDDDDDDDDDDDDD
@1SC
GTATCAGGAAGGCTGCCAGGGACTGGGCTCCAGGGGCAACATTTCCCTGGGTCCTGGAGAAACCCTAGTACCTGGGGATACGGAGAGCAGTGTGATTCCT
+
;1?DBB;?A:22ACG@CB<EECGB=BFD;88CC0000?B?F@FBCE<<BGE=@CEE@>A36;;@;@@C>>3;@C9?BB8<(8?19&2?:<4:CC@>ACDC
@1SD
CACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCG
+
@<@D;?ADB?F?B@GGGGG>FHIEAFFH@EBABFBGIGIIIEHIIGDHIIGDBH=@@@@D77@DDEEH@EEC?;B:BCACC>CA3A?B?A>>ABACB??B
@1SE
TAGGAAGTAGCTTATTGCAAAGATCTCACTGAGAAATAGTTTATGAATTAAAATCTTTCAAATAGCCATGGTAGAAGGGTACAAAAGAGAAAAATGGAAA
+
+17+27+22<<C<++,>2,,+++<+,3><?7+2+1:**:*******1:***0:**07*9*0**9***)).)).))))('())).)..(.7).(.((((--
@1SF
GATTTTGCATATGACTCAGAAGTGCCTAGCTGCCACTCCATTTATATGAGGCAAGAAGGCTTCCTGGCTCATCCCAGCAGAACAGAAGGCTGTATGTTTG
+
@@@FFFBDDHGHGGIJIJJJJIDHGFHJIJJJJIEHHBFGIJJJIGIIEHIIJIJJJJJJJJIJJJJJJJJJJJHHHHHFFFFFCEDEEBDD@CCDDEDD
@1SG
CCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGT
+
@@<DDDD8A<DB??C2:1<:CAB@FH@FDF=6B?(97CCC>FHHC7777=CDEHE?3?>;BBAC:;;AC15;=(;;:A(,,(8?BCC?8<@CC?>:@BB?+
@1SH
GTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACA
+
=?@D;?ADDFDDHEGGI@F@EE@H?FC?E9DDHI@FHEBBDDFB??F@B;9/B8BFH;).8@==CA@>=EEHEB6=;@;AB=@C?B??CC:55@CC>AA
@1SI
GAGATATGTCTACAAGTTTGTGTGTGATCCAGAAGCCCTTTTCTCCATGGCCTTTCCAGATAATCAGCGTCCACTGCTGAAGACAGACATGGAACGTCAC
+
???BBDDDDBDBFEHHCFII3C<CHH?<AHBFHGGI@EHHEFB@??GECGCHEHGHGIA38=BGCCA=FHCAEE;A;A?;B;CCCC3@@CCCCAA;BBB<
@1SJ
GCAGAATGCCACCAAGAATGGCAACATGACAGAGGACCATGTGATGCACCTGCTCCAGAATGCTGACCCCCTGAAGGTGTACCCGCCACTGAAGGGGAGCT
+
@@@DDDD4DACF?EHB+<EH@EFGH@E<CFFG@G?EDEHGAD<GCDDHG?;@BFGHH>GH;)7C7=DHC7B<;BDB@6>>;ACCBB?BBCCACCC7&5)0<
@1SK
TGCAGTTTGAAAAGGACAATTTGATAACTAAGCAGAATCAATTAATTTTGGAAATTTCAAAGCTAAAAGATTTACAGCAGTCTCTTGTAAATTCAAAGTC
+
@@@BDD?DDDFHBBHBGHGGGIICHCAHGGCA<F>AEHGIEHGGHEG?BGAFGIHIADHGHICGGIAED;FA;D;CAEHHAEEFDED??@>>@CCEEC>C
@1SL
GAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAAC
+
BCCDDFFFHHHHHJJJJJJJJJJJJJJJJJJIIJJJGIJJJJJJJJIJGIIIJJJIIJJJJIJHHHHHHFFFFFEEDDEDDDDDDDDCDEDEEDDDDDDDD
@1SM
TCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATC
+
@@CFFFDDFDHHHJJJIIIEGEIIJJJIJIGIGEGFHHIIEIJJGAGHHGIJGICHICFGEGIJHGFHHHDFFFFFEDAACEDDDDDBBCCDEDDDCC
@1SN
ATTCTGTTGTTTCATGTTTCCTGTGTTTAAAATCATTCTTAATACTGCTTTTTAGCCTTGCTATACATCCTGACAAAATTAGGATTGCAACTGGACAGAT
+
=?@DDDDFHFDHF>@EFGH@EEHEHEG;H9AA@E@<G?FB@GGGAGGGIC@E?DCGHGEHIIJIEHGCHI<CA@FGIGIGIIHFEEEEFDDDE9@>@=CC
@1SO
CTCAAACTGGAGTGGGCATATGGTTATCGAGGAAAGGACTGTAGAGCTAATGTTTACCTTCTTCCGACCGGGGAAATAGTTTATTTCATTGCATCAGTAGT
+
?@@D;D?:?A?D:C?C@F>BFFB3AFHFGFFGABGIEBFEG9?F?FDDDFEF=CGEEIIE@FA@@@EAEDCB@BB@BAB:BDABB@@DDABA@AB>@::@D
@1SP
GTAGCCCAGTGGCTCAAGTGGGCTGAAAATGAGTTTTCTTTAAGGCCAATTGACAGCAACACGTTTGAAATGAATGGCAAAGCTCTCCTGCTGCTGACCA
+
;;@:?DDDDAF??;EFBD?FFGF3CCFFECEGECFAF?FGEFGF>;0?BFFEEEF>F>AFIIF@EFFIEEEBEC?;@2BBC;3;A>@;A(>@BA@@A<A@
@1SQ
AGCCAGGGTCGGATTCCAGTTAAATGGATGGCAATTGAATCCCTTTTTGATCATATCTACACCACGCAAAGTGATGTATGGTCTTTTGGTGTCCTGCTGTG
+
?@@DDFFDDFHGDIJEGHIHGHIJIIHFHIIIGIGHIIIJJIJIJIIJGHGEGGIIJJJJGIIJGHFFFCC6@@BCDEDED>CCDDDDD9?BDDDCCCDCD
@1SR
CAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJIIJJJJJJJJIJJJJJHHHFFBDFFDEEDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDD
@1SS
TGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGC
+
@@@DDDADDHFDFDAHIG:E;EHIIIGBHGIIIIGHCHIHGGGHIGGEGIGHGIGEFGGHAC7@;ACEHHHEDDE>BCCCCCCCBCCCCC@BCBBAB9@B
@1ST
ACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGT
+
CCCFFDFDHHHHGBHGGIGE@GIIGHCHGEFGGIIIIIIIGEGGDHHGGCFGFGGHIIBBGEEEHAEEFD@DFEADBBBDBDDBBDD?DDDCCC@CAB?>9
@1SU
CTTCTCCCTTTATTCCAGCTGTCTAACTGACAAGACCTTTCTCTCTTTCTTTCTGCCTCATGCTCTCTCCAACAGGCTTGCAGCCAATTTACTGGAGCAGG
+
@@@DDD:=ADFHFGDFHIFHHCHHFI<HH9FGAG?;DAHGHIHGDDEFDFGIGIGGGGHIGDHIIGIGIIIGIICDHCAEHDDE?ACCCACCCCC<ACBC@
@1SV
CCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGT
+
CCCFFFFFHHHFHIJJJJIJJIIIIIIJJJJJJJJJEHIGIGIIGIIJJIJIGIIJJJJIIGIJGGFFFDDDDDDCDDEEDDDCBDDDDDDD@BDDDDDC
@1SW
TTTTTAAATGGCATTAGTTCTGTGTGCTATTGGTGTTTATTTGCATCCACCTGTCCAGTTGCTCTGCTGTCTTGTGTTTTTGCAGCCTCTACAACCCCACG
+
CC@FFF;DHDGAHGIGI@CFII>@BFEHHC@HE<:CCEEGIIIEGEHDFHGHGEHIGHBEFDHD>F=FEFHCGI@CCHHEFF@BDCAEEDECDDD@B@B?B
@1SX
CTATGATAAAAACATTATGACCAAAGTGCACGGCAAAAGATATGCTTACAAATTTGACTTCCACGGCATTGCCCAGGCTCTGCAGCCACATCCGACCGAGT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJHIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJHHFFFFFEEDDDDDDDDDDDDDDDDDDDDDDDDDD
@1SY
CTTCATGAAGACCTCACAGTAAAAATAGGTGATTTTGGTCTAGCTACAGTGAAATCTCGATGGAGTGGGTCCCATCAGTTTGAACAGTTGTCTGGATCCAT
+
@@CFDFFFHHHFHIIIGGEHIGHEDFHHJDEHIJGGGBCFCCGGEFHGEFE>DFGEGIIHGHGIIIJJFEGC6AA3?CEDCDE>@;AA@CCC;ACDCCCDC
@1SZ
GGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTC
+
;??DBAD+22<CBEEEEEB<<CFBBAEEAC?8?DDEEDEDCDD@DB@BC@DAEI@7AA==CCCEDEDFD>95;6(;>A9?>??AAA???8>?>>???:>>
@1T0
TGACAAACTCCAGAAAGCAAGAATGCTACTCCCACCAAAAGCATAAAACGACCATCACCAGCTGAAAAGTCACATAATTCTTGGGAAAATTCAGATGAT
+
C@@FFDFFHHGFBHIIGGIJIIIIIEIIIEGHIJIDGHGGFEHIIJJGIIJEGGIIGIIJHFHHCEEFBDFFEE@CEDDDCDDDDDDDDCDDCCCCCCD
@1T1
GCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGG
+
@@@DDDDFHHHGHJJIHIJJGIEHIFBGGGGHIIIIJGGGEGIJIJJJIIJIGGJIIJHHHHHHFFFFFEDDDDBDBDDCDDBDDDDBBDDDD<CACDCDC
@1T2
TTTTATTTATTATTTCTCCTCTTAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJHHHHHHFFFFFFEEEDDDDDDDDDDDDDDDDDDDDDD
@1T3
TGAAAAGGGCCCCAGGCAGTTTTATGATGACACCTGTGTTGTCCCAGAAAAATTCGATGGAGACATCAAACAAGAGCCAGGAATGTATCGGGAAGGACCC
+
@C@FFFF=FBHHHIJGIJJGIJJJGGEFGIJJJIIJIDGGIHIHGIIJJJIIFHGJGIJJGGIFHHHHHFFFFECCEEDDBDDDCCDCDBBDBBDB?BBD
@1T4
AAGAAAGAAAAACCACAAGGACAGAGAGAAAAAAAAAAGAGGAATCTCATTCTAATGATCAAAGTCCACAAATTCGAGCATCACCTTCTCCCCAGCCCTCT
+
@@CFFDDFHHGHHIGIIJIHEHHGJIHIGHEGIIJIJJI=CCEB@BDF@CEDADCECA>CCDCD>ACCCC@BCDD<A9>BCCCDDDC?4@CCDDDDBBCDD
@1T5
CCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGAT
+
CC@FFFFFHHHHHIJIJJJIGII?FHIIJJIEIIJJEGGGGHIIGIJGGGHIJGIGIGAD>CGHGHGGJHHHFFFDDACEEEDDDDDDDDDDDCBBDBDBD
@1T6
CTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCC
+
@@@DDDEFFHHHAHI@HIICHIIIG?G9DD?FDGHDGCHIIGI?FHGHIIDIFIIEHI@ECHHGHDF>BECCCCDDDBB@7<A@@>C@CB@BBDCBAAC
@1T7
TGTAATTGAGAGGAGAATACGTATTGTTACTAGATGAGTTTTTGTAAGATCCGAGGGTGATAGAGAAAGAAGAAAACAGCAGGGGGCTGAATGGCCG
+
=:1=AAB,22=+22AD++33:3AD;<++2<?F4****11*111))09?000*((.'---.).).=AC?).(.7;>(6(((,;?'''&&)24(+:(+5
@1T8
CTTCAAATTCTCATTTTATTGCCTGGACTGGTCGAGGCATGGAATTTAAACTGATTGAGCCTGAAGAGGTGGCCCGACGTTGGGGCATTCAGAAAAACAGG
+
CCCFFFFFHHGHGIJIJJJJJJJIIJEGJJJHIJHIJJJJJJDHIJJJJJIIIJJIGGGIIJJJJGGHHAEDFFFDDDDBDDDDDDDDDDDDDDDDDDDDD
@1T9
CTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGT
+
::1A==ADFF?F<AG<FFAAIB:<<:++<??00:::DDGA@9BBB?*B??8D@===FCFIE(..@77?7A777;BDD=@3?;/89?AB@BA54@<832<B4
@1TA
ACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTAT
+
@CCFFFFFHHHHHJJHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJIJJJJJJJJHHHHFFFFFEEEEEEEDDDDCDDDDDDDDDDCEDE
@1TB
CTCTGATGGACAGCAGATACTTGTGCCCAGCAATCAGGTGGTCGTACAAACTGCATCAGGAGATATGCAAACATATCAGATCCGAACTACACCTTCAGCT
+
@CCFFEFFHHHHGIJJJJJJJJJGIJJJJJJJJJIGJJFHIIJJHIIJJJJJJJJJJJJIJJHIIJJHHHGHFFFFFFFEEEEDDDDDDDDDDDDDDDDD
@1TC
TTCTTCAGTATGCACAGACCTCTGATGGACAGCAGATACTTGTGCCCAGCAATCAGGTGGTCGTACAAACTGCATCAGGAGATATGCAAACATATC
+
@@@BDD;:DFBHDBGHGBHIIIIIIIFFHGGGIIIDIIIIIIGHIIGIIGIIIBFIIDCHFGAACGHHIFHFEHEEEEEECCCCECCECCBBCCEC
@1TD
CGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTT
+
CCCFFFFFHGHHHJJJJJJJIIJJGGGCHHIJJIJIHHIIIJJJJIJJJJHHIIIIJJIGEHEFFFFFACCECDDCBCCDDDDBD8>CCC?CCCCD>CCDD
@1TE
GCTGGCTCCTCTGCAAGGACAAGGGTTAGAAAAGCAAGTCCTGGGATTGCAGAAAGGACAACAAACAGGGGGTCGTGGAGTGCTTCCTCAAGGGAAGGAGC
+
@@@DDDEFHHGHGIDGIGIIIIBFI8CGHIJIGJGHIIHIJHEHIIIIHBGHGJIJIIGGIIIJIHHHEFFB,8=,;@@D@?C>CCCDCDDDDDDDDD@@B
@1TF
CCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGG
+
<?=DD?=;FDFFBEBCCEAF3F>9CE:FF<<GDFFF9DFFCFEFFDEAD3@ECDE;7=ACEE>;@@@@(66;>@(,5?38)5?>A:4??@@@BBB?B@BBB
@1TG
CTGCTTAGTAACTAGCAGAAGTGTTCCTAAAAGAGTCATACACAGGCCCAGGGCAGTTCTTGGGTGGGTCCATCCGGCCTCCACTGGTGACAAACTCC
+
@@?BBDD8ACF?CCEEHHGII:AFHIEHEBHBE@BCAFHADFAFGHHEGEGGDBFHIEIGIGIIIGEBD>;@DC;>@BBBBBC<CA?:?CCCCCBAAC
@1TH
CCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGG
+
@@@DDDB:FHFHHBHCHIIGI@HEEHIIEHIIIIIEHIIIIGBGFGIEGGIIIIGIIIIHIEEEEBHHFHFFD@D@DCACA@@BBCBB<;@BB>CBCCCCC
@1TI
TTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGC
+
8??D=ADD<A=CFEFAG<EBEB::<3C+C@?<EC?GGIIIIBB;B@FFA68=B=F>@@==C;DC?E7?>@>B?BC>>>;AA???;;<BB@AAA?@B<2882
@1TJ
GGACGTCCTATGTACCAACGCCAGATGTCTGAGCCAAACATCCCCTTCCCACCACAAGGCTTTAAGCAGGAGTACCACGACCCAGTGTATGAACACAACAC
+
@@CFFFDDHHDFHGHIJGCHIIEHGDG?FIIIGJGIIGGEHHHIJGIGIJGGGGHHIGHFHHEFFFFFFDDDACDDDDDBDDDDDDDDDDDDEDDDDDDBD
@1TK
CTACAAGTTTGTGTGTGATCCAGAAGCCCTTTTCTCCATGGCCTTTCCAGATAATCAGCGTCCACTGCTGAAGACAGACATGGAACGTCACATCAACGAGG
+
CCCFFFFFHHHHHHHHIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIIJJJJJJJJJHHHHHFFFFFEEEEEDDDDDDDDDDDDDDD
@1TL
AGCAGCTGGGACCTGCAGCCAGAACTTGCAGCTCCACAGGGAACTCCGGGACCCTTGGGTGTGGAGAGGAGAGGGTCTGGGAAGGTTATAAACCAGGAATC
+
==<A1<A7+2A3<ABBABBACACCB>ABBB>7==1?)0:0)85A*/><AA:A;A3;;=6=@9=@>@;==9,98(38;83389?898:?;;??=99(((288
@1TM
TCCTACGCGAAGAGGAGCCAGGGGCGGATTGAAGTTAAATGGATGGCGATTGAAGCCCTTTTTGATCATATCTAAACCCCGAAAAGTGATGTATGGTCTTT
+
58(:?)8((05(>?1(=.()27((0;6=3=((7---;=37((7;6<('&)2++3((+(5(2:<:<=/;2:62::((8((&)&&)5(22(+3(+2(2:((++
@1TN
TGCAGGCCGAGTGTGACCAGTACCGCAGCATCCTGGCGGAGACGGAGGGCATGCTCAGAGACCTGCAGAAGAGCGTGGAGGGGGGGGGGCAGGTGT
+
+++<A7AA8A)A=C7@,<AC7C?4:4):)00*0097==A6-=5;5=@<6/(95(5,55(,95(+8;<;((((++550-8;<&00&))&&&)))(+(
@1TO
GAGATTGAAAAGCAAAGGAACACTTTTTCATTTGCTGAAAAAAACTTTGAAGTTAACTATCAAGAGTTACAAGAGGAGTATGCTTGCCTTCTCAAAGTAA
+
BBCFFFFFHHHHHJJJJJJJJJJJJJJIIJJJJJJJJJJJJJJJJJJJJJJJIIJJJJJJJJJJJJHHHHHHFFFFFDCCEEDEEDDDDDDDDEDDDCDD
@1TP
GGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGC
+
CCCFFFFFHHHHHJJJJJJJJJJJJIJJJJJIJJJIIHIIJJJJIHHHIJHIIJGIJGHFFFDDDDDDDDDDDDDDDDEDDCCDDCDDDDDDDDDDDEDDB
@1TQ
CTATCAGGCTGAAAGTTTGGCTTTTCATGGCCTGCCACTGAAAATCAAGAAAGAACCCCACAGTCCATGTTCAGAAATCAGCTCTGCCTGCAGTCAAGAAC
+
?@?DDDDBFFF;:<C:AC>FFFF:<F9C?GDGB;EDBFFEE@BDFGFCEG;FFFEBFFBEE(=@@E77?=AC)=);?DDBAB@@B@@>(;?3?,:5:A:5<
@1TR
GAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTG
+
@@@BDD;DHAHDDHHG?FF<F<@GFDHBHEHGAFDDHEC*?FB<B9CA8=CFHGHGC;@GE>>>AEHBDE7>AB?CC@BC?@CC53>@CCC?>><??B<>A
@1TS
CCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGG
+
CCCFFFEDHBFDDGIIIGIIIGIIIJFJJJFHIIJGGGGHGHGCDHHIEIHIJJJJJJJIGIJHHHFEE@CFDEFEEDB@BDDDDDBDDDDDBACDDCECD
@1TT
CTCCTGCTCAGTGTAGCATTAAGCAGGAACGAATTTCATATACACCTCCAGAGAGCCCAGTGCCGAGTTACGCTTCCTCGACGCCACTTCATGTTCCAGTG
+
@@@DDDDADFHAF<EGGIIIGIG<FHDHE@FHGIIIHCHGGIIIIIIIIIIDGGHIGGIH@ACHGAHABC>;<=ACCCC??B@BB9@@ACCECCDCCEC:A
@1TU
CAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGG
+
CCCFFFFF>DFHHJGIJJJJJEHIGGGGIIJIIJIIEAGIHJJGGIBGIADGGHIEHHEFFFDEFDFFCCC>@CCBB;?BB?CCCCBBABDBDBDD@CCC
@1TV
ATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGC
+
@@@DFFFFFDDBFHIJIJIJGIHHGIIGIIGIIFI<GHJHHHHIGI@FGIBHEHIJJIGIJJIJIIJIFHHFFFFFFFEDEECDDCCCDBDDBDDDBBBB
@1TW
CGTTGGGGCATTCAGAAAAACAGGCCAGCTATGAACTATGATAAACTTAGCCGTTCACTCCGCTATTACTATGAGAAAGGAATTATGCAAAAGGTGAGC
+
@@@D?BDFDABFHGAHBDFHGHG@GHFCA?GBCHGIGFHEBEDHIDGHEB@GGAHHEHGGIAE<<B@@BB>>>6;;@?CBDC@CCDDCDCCDC?:@@?C
@1TX
CCGAAGCCATCCAGCCCCCGGCAGGAGTGCACACGCTTGATCCAGCTGATGCCCAGCCCCATCATGCACCCTCTGATCCTTAACCCCCGGCACGCCGGGAT
+
+1>A=)0A=+@C7C3+2)2@:?)?0)))9?B*).-''-((..>A)=A;)..).).((,;3(((5(,,,:5==2((5;?3((((53+95)&&&0&)9&&&5;
@1TY
GAAGAAAAATAATAGCAGCAACAGCAATGTGAGCAAGAAGGAGCCAGCGCCCATGAAGAGCAAGCCCCCTCCCACGTATGAGTCGGAGGAAGAGGACAAGT
+
B@CFFFFFHHHHHJJJJJJJJJJJJJJJJEHIJGIJGIIJJJJJJJIIJJJJJJJJIJHJHHHHHDFFDDDDDDDDBCDDDDDDDD@DBBDDDDDDDDDD>
@1TZ
CCTTATTCAAACATCAACAACAGGGACCAGATAATTTTTATGGTGGGACGAGGATACCTGTCTCCAGATCTCAGTAAGGTACGGAGTAACTGTCCAAAAGC
+
@CCFDFFFHGHDHGIJGIGGIGIHIEGIIJJEGEIJIJJJJJJHHJJDGGGIIJCDHHGCHEEDFFFFFEEECEEACCCCCDDDBDBDDDEDCCDDDDDDD
@1U0
TCCTAACTCACACGGTGTTACATGTAAGCAAACCTTCAAGTGTCCAAAGAAAGGAGGGGGAGTTCTCCTATGATAGGCAAGCGGCCTGTGATCTTTTTAAT
+
((085)2).:)).-(-.-8)<).)2=;:)).6(()))069767)).0)0)(0=<(.''-'5'9=((-:((((-(:(,(,(((,585&6+(42((++(:852
@1U1
ACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTT
+
@@CFFFD?FDHHFIJJJIJJIIJGIIGIJIJJIGIGIJIIJIIIGEHIJFJJIJIJJ9?CCDEEDDABDDDDDDCDDDDDCCDDDCCBCDCCDDECDCDDD
@1U2
GCAGAGTGCCTCAAAAAGAAAAGAGATGAGAGACCACTCTTTCCCCAAATTCTCGCCTCTATTGAGCTGCTGGCCCGCTCATTGCCAAAAATTCACCGC
+
CCCFFFDDHHHHHJJJJJJJJJJJJIJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHHHFFFFEDDDDDDDEDDDDDDDDDDDDDDDD
@1U3
GTCAAAGAAGACATAAGGCCCCCAGGCTAAGCCGAGCATGAAGAAAAGACGAAAACAAGCGAAGATATGGGGTGGTAAGGACTGCAAAGCTACGAAAAGC
+
(0(22.))8.:4)2.2).)((--((-(2)..):(3557))..).)).)(.''-:3396)(,(,''(,(,(,,,&&&(++:((+(((+(((+++&)(0)(+
@1U4
CAGGGGTATAACACTGGTGCTTATGATACCACCACTGCTACAGTCCCCACCACCCAGGCCTACTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGGTT
+
555:1/>@7))))):939)=:<?86)=@>???@<73));6=36<>)07>;?5=1-=:(.(<)).<:.).979).;9==(:(9;;31;(-((:,3276(,3
@1U5
CGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCA
+
@@?DFDFDCFHHHGHGIJJIJJIEEHIIJJIIIGGCHIJGHHIGHCFHGEGIGCHHGHHHFCC;8A?;;@?BCDDC@CDDDDDCD@BDDBA@BBDDDCC
@1U6
CTGAGGCCGAGTCAGCTGCGCGGGCACCCGGATCCACCGACAGAGCGGCGGCGGGGTCTGGCCAGGCGGTAGGCGCCGCCCAGCCCCGGCGGGGACGAAGT
+
((--((=9(@(-<1):<)@/=6?2/'-=9553',))6=/;'2'2,;55&)5-&0&70028::;6+8(&5&0&2:&50&05&&+282&&0&&095)&&&&++
@1U7
TTGAAGGTGAAGATGGCGATGTGATTTGTTTGGATTCAGCTGACATTATGCCAGTTGCTTTAATGGAAACGAAGACCCGAGAAGGGCTAAAATATATGGT
+
;;;@3=@4)2):;?).@55(269>4643.)))())2=)<)0063.:6)=1)<)77>1>)6==?;>>?)<09==59)863=<<;75'(,2(,(5(+652:+
@1U8
CTTCTCCCCAGCCCTCTTCACAACCTCTCCAAATACACAGACAAACTCCAGAAAGCAAGAATGCTACTCCCACCAAAAGCATAAAACGACCATCACCAGCT
+
@?@DADDBDHHHF?HAGIBCHBFB?F?GFC@D?DCGBF@HD:9???F<80?<B==CGHIEC@HIGGGHHEHEDBDCCC>ACCCCCCCBBB@>ACCCCCBBC
@1U9
CACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGC
+
CCCFFFFFHHHHHJJJJJJJJJJIJJIJJJJJJJJJJJJJJJJJJJIJJJJJJIJIJIIJIJJJHHHHHHFFFFFDCEEDDDDDDDDDDDDDDDDDDDD
@1UA
GTCGAAATGGAGCTGTGAAACACGATGGAGGATGAAAAGACGAAGAGCACATAAAAGGAAGGCAAAACTGATGATAAGCTTAAGCTGTGATGGGCGAAGTG
+
(0(88=((6.8(224)))).):(((2((.((1<39))))()(-(7=())()))))/)-667;(.(.)..61.63(((((((((((,(((,(,((()&0)+(
@1UB
CTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTAT
+
@CCDBBEDHFAHFEEHIIIGGCBGEHGHIIIIIGEFHDHGIEHIIGDHIIIECEHIGIIIEGHIGGIFCHHCHFFF>CAAEACDDDBCDDDD?>@BDDACD
@1UC
CCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAG
+
CCCFFFFDDHHGHJJGIJJJJJJJJGIJJJJJJJJJJJIJJIJJIJJIJJJJJJJJJJJJJJJIGHGHHHFFFFFFDEEEEDDDDDDDDCDDEDDEDED
@1UD
CGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHFFFEDDDDDDDDDDDDDDDDEDDDDDDDDDDDDDDDDDDEDD
@1UE
CCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCC
+
C@@FFFBDHFAHHIHIIIGGEHHGGCGHIIIGGG?FH>FAGHGGGBDGHG@FHHIIIGIIIBEHHDD?BFC9A?;=;ACCDECCC<?B@BB<2<CCCCCCC
@1UF
CTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCT
+
;@@DDDDDHDFHHJJJJJJIJJJJJIEHIJIIJIIIJJIIIJJIGIGJIIIIJIFIHEHIIJJIJIIHHHHHFFC>BDD@CDEDDDCDDCDDDDDDDDDCC
@1UG
ATCCAGAAGCCCTTTTCTCCATGGCCTTTCCAGATAATCAGCGTCCACTGCTGAAGACAGACATGGAACGTCACATCAACGAGGAGGACACAGTGCCTCTT
+
@CCFFDBAACFHHGGHIGHHIJIJJ3CGGIGGIIIIJCGG?FHIIIFHEIIGGGHIIJFHGGIJIEGGHHHHEFFFFCEEAA@?8?;@DC?AAADDDDDDD
@1UH
GTAAAGTCCAACCAAGCCCTCGAGCAGTTATTCTCATGTCCTGTATAACCAATGGAAGTGGTGCAAACAGAAAACCAAGTCATACCAGTGCTGTCTCAATT
+
:==AA>22+2<;<+7==<+@A221@?BA?ABA:*0*:=:*:70=7==A?A=(/==98)=A;>A4>B4..=3=>)75=@>5>>33;=;;;=9(;;:9(;==?
@1UI
ATTAGAGCTGACTAATTCTAAGCAAAAAGAAAGACAGTCTTCTGAAGAAATAAAACAGTTAATGGGGACAGTCGAAGAACTTCAGAAGAGAAATCATAA
+
@?@DDBBBFFDFHEGIIEHGFB>HEGHIIEHGDHIIIGHHHEHEEBDHHEEHIGABD;)=FCDGHIFIGH<=AEFFBEDDCCACAA>5>;ACDD@CC@@
@1UJ
ACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCT
+
@@;DDDBDFHHDDIGDHHCAF@GHIGCH8?BFCGEGGHEHI<4@9CFCHGGEE>EHEDEECECDCCCA@BBACBCCAC>CCCCCCBBBBBBBBB@BCBBC
@1UK
CTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACT
+
CCCFFFFFHHHHGJJJJJJJJJHIJJJJJJJJJJJJJJJJJJJJJJJIJJIJJJJIJHHHFFFFFEEEEDD?BDDDDDDDDDCCDDDDDDDEEDDDDDDDD
@1UL
GCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATG
+
CCCFFFFFHHHHHIIIJJJJJJJJJJJJJJJJJJJJJJJJIJJJIJJIIJJJJJJDIJJJHHHHHFFFFFDEEEDDDDDDEDDDCDDDDDDDDDDDDDDDD
@1UM
CAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCC
+
@@?DDFDFGFHFHGIIJGHIJJJHHAFCDGEHGIGIIIJJFEGIJJIIJGCEHHGH=@?@@B>CECECCACA@C;?:CCDCCBB<?@ACDCBA?CDCADCD
@1UN
CCAATTTACTGGAGCAGGGATGACGTAGCCCAGTGGCTCAAGTGGGCTGAAAATGAGTTTTCTTTAAGGCCAATTGACAGCAACACGTTTGAAATGAATGG
+
@@@ABDD;FDBDF@>F;=FHHIEHBAB>@HEHGBFG?8*BDEDDBBDDAHIIIGGDF)=@DGIEH==EHEEDEDED@>@66@C==BB?A<8ACC@::@:@@
@1UO
GTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCC
+
;(;=@<=<6843)<@;6@@@<:6@<:)-@.1>::9?36=:6????537==5636(..;6>./=8>;.3=9.6693==8=?;7(:=7;;;<(577;228;
@1UP
GTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGAT
+
@@@FFFFFGHHFCFHGIJJIGHBEHIIIIJJIJJJJJJE9DDGIGIIGGHIGIJJJJIGIIGIIGHFEHDEEDFFEEEEEEECCCDDBB?BDDC@CDDC@C
@1UQ
CACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGAT
+
@@?DDDDD8>FFDBFEF6GB?BEHEG9DDG))::D;9?<DHGE<>D4)8=CFG=7C>E@GHEHFHFBBD?AC@CABC??C>CDD@@CCBBBB7?@<@CCA:
@1UR
TGTGATTGCCGGCTCCTCCAAGATGAAGGGCTTCTCGTCCTCAGAGTCGGAGAGCTCCAGTGAGTCCAGCTCCTCTGACAGCGAAGACTCCGAAACAGGTC
+
:=1BDDADFDH<?FDC;ECFGAHDBEB<9@=;DCBGG6??D>88.8/=8F@;'(..;?CD3;@CCC:>>>;@AA9CA@:ACB=<BB@A@ACBBBB9?CB:@
@1US
TGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGG
+
CCCFFFFFHHHHHJJJJJJJJJJJGJJJJJJJJJJJJJJJJJJJJJJJHIIJJJHHHHFFFDDEDEDDDDDDDDDDDDDDDCDDDDDDDDEDDEDDDDDDD
@1UT
GGGAAAGTGGCATGGTGATGTGGCAGTGAAAATGTTGAATGTGACAGCACCTACACCTCAGCAGTTACAAGCCTTCAAAAATGAAGTAGGAGTACTCAGG
+
@@@;D+A=DAFFFII:CEEHAEHEEEA?BFEECC?FBFFAF?GB9BDEF>FFII@FFEFFFFBF@FAFEE;=EFDEEEDDD>B;AC;;3>->(55;;A:?
@1UU
CTCCGAGGACGGGCTGCATAGGGAAGGGAAGCCCATCAACCTCTCTCATCGGGAAGACCTGGCTTACATGAACCACATCATGGTCTCTGTCTCCCCGCCTG
+
CCCFFFFFHHHHHJJJJJJJIJJJJJJJJJJJJJJJJJJJJJIGIIJHHHHHFFDDEDDDDDDDDDDDEDDDDDDDDDDDDDDCDDDDDCCDDDDDDDDDD
@1UV
GCCAAAGGAAAGGAGAAAAAAGAAAAAGGAAGCAGAGGAAGAGGATGAGGAACTCTCCAACTTTGCTTACCTCTTGGCCTCTAAACTTAGCCTCTCACCA
+
?<??DDD>DB33??:<?E@EE11?)?CD=3:BDAD;D=29(=CC=CACCE@A@)@)=C=A??A3@;?AA;AA>-;;3;>A?AA>>:A33(5>>>:A>424
@1UW
GGCTGATTGAAGTGAATGTTGGGGCCGATGTCGACGGCGATGTCGGCACGGGAGACGGAGATCAAGGTAGAGGGGGACGCCAAGAGGGGAGACTGCTCG
+
(0(--(2.6<)<)2.))))36((((--(-:().((07'--''.)(,'''''',3&88&))&(+2(36+((2(+)&&&&&&&)&8(250:&0&((+(+(+
@1UX
AAATTAGAGCTGTCACAGAGACTGTCTGATCTTTCTGAACAATTGAAACAGAAACATGGTGAGATTAGTTTTCTAAATGAAGAAGTTAAATCTTTAAAGC
+
:=??4A+BDBDDAEE4CDEF?EF@33CC++2AAC<E*1?CAD@DD4BDB;?DDDD>*?B?*8=BB8@==@A)8.=CA4.=?CCDC)7@DD3.6((6>A>5
@1UY
CCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGG
+
@@@DDD>BDA>FB>FBGIIIIGEHECAHGGBHIACHIIHGBF@FGIIEGIIIIHHFEEDECE>;ACCCC?>5;5>;ACCCDAA>@@C?A<B3:>C:@<@
@1UZ
ATGACTGTGGCCTCCAACTAAGGGTCAGCGAGGACACCTGCCCACTGAATGTTCATTCTTATGACCCCCAAGGAGAAGGCAGGGTGGATCCTGATCTGTCC
+
@@@FDFFDFBFHBGIGIDEHIGIGEGEED@:FG6FFHGIHFGEEHGIIIIICG@EEHIIGHHFHEEHFFDCCCBBBACDB@DDD9?BBC@?@CDCDDDEDC
@1V0
CTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGTAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTT
+
@@@FDDDDDHFFHHIIIIJIGJJGGHHHJIIJJIIGGIIJHJIIIIIIIJJJJJJJ;;FGHIGIECEHHGHFDEABBBBBBBDDDDDD>CCDDDCBD(59?
@1V1
GAAAGAGGAAGTGGAAGAGAATAAAAAAAGCAAAGCCAAGGAACCTCCTCCTAAAAAGACGAAGAAAAATAATAGCAGCAACAGCAATGTGAGCAAGAAGG
+
@@@DDDDDHFHAFHIIIGG>GHIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIGIIFHHHEECCCCCCBBCCDECCCCBBCBBBBCCCCCDDCCCCCCCCB
@1V2
AGATGACCCCCAATTGAAAAGAGAAATAAGGTTAATGAAAAACAGAGAAGCTGCTCGAGAATGTCGCAGAAAGAAGAAAGAATATGTGAAATGCCTGGAA
+
@@<DDBDDBFDHFGHIE?HH?AAAA?FC9EFCD9CFHBG?DDHCHIF;BDCG9@FB=;@CBE@?;AEDECCAA9;??CCCCBCCECDDD@CCC:ACCBB>
@1V3
CAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATAT
+
C<@FFFFDFHHGGIJJJEHIGJJIGGHIIGGGIJEGIJIJJGIJIGJJJJIJFIIJJJJIIJJJHHHHFFFFFCCCCECCCDDDDDDDDDDDCDEDEED
@1V4
GGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCT
+
CCCFFFFFHHHHHJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJIJJJJJJJJJIJHHHHHHHFFFFFEEECEDDDDDDDDDDDDDDD
@1V5
ATTCTAATGATCAAAGTCCACAAATTCGAGCATCACCTTCTCCCCAGCCCTCTTCACAACCTCTCCAAATACACAGACAAACTCCAGAAAGCAAGAATGCT
+
CCCFFFFFHHHHGJIJIJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIIIJJIJIIJJJIHHHGHHFFFFEEECCDDDDDDDDDDDDDDDDDD
@1V6
GGAATTTTTGGGAAATATGAAAAGCCAAAATTTGTGCAGTGTTTAGCATTCTTGGGGAATGGAGATGTTCTTACTGGAGACTCAGGTGGAGTCATGCTTAT
+
CC@FFFFFHHHHDGGIGGIJIJIJJIJJJJIJJJGFHJJBGDGIIJJJJJIJJJJJJIJEIJIJICHHGHHFFHHHFFFFDCEDED;ABBD>CDEDDDEDD
@1V7
CTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTT
+
@@@FFFADDHHGFGIII<BFHHGJEIIGJJJJICD@DHIEHIDH<BFAFGHGIJ9CFIFGIGIEIIGHGFHFFFCA@ACEDDDCDDCCCDDDDBBDDDDDD
@1V8
ACATGATCCGCCGCCTCTCCCCGGCTGAGAGAGCTCAGGGACCCAGGCCGCACCAGGAGAACAACCACCAGGAGTCCTACCCTCTGTCAGTGTCTCCCATG
+
@C<DDDDEHDFFHIGGHHIHHGIGIIIADDB;D;BF;FGBDGGCAHFFFBA>BBBBB9<9?C9?BBB@B8?BBB9>CCCC?BA@C@@CCC4>4@:>@?<CC
@1V9
GGAAGAGTTAAGAAAGGCCAACGCAGCGCGAAGTCAACTTGAAACCTACAAGAGACAGGTAGTAGAACTACAAAACAGATTATCCGAAGAATCAAAGAA
+
@@7?DD?2CFDFHB@EFBGGIGEAFG8F<@GIBBBFG;;FGGIDG(=D?EEH)(;B>A?.;;;;@CC@@C;:@CBBBCCCCCC(4+<?>>>@(4>>4(2
@1VA
AAACATATCAGATCCGAACTACACCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATGACATCTCCTGTGACTCTCACCTCTCAGACAACTAAGAC
+
CCCFFFFFHHHHHJIGIJIIIJJJJJJJIIJHJIJJGJHJIIGGGIIJIJIHIJEHGGIIIJJJIIJJJIJHHHHFHFFFFFDEEEDEDDDDDDDCD
@1VB
GCTGTATGTTTGAAAAGGGCCCCAGGCAGTTTTATGATGACACCTGTGTTGTCCCAGAAAAATTCGATGGAGACATCAAACAAGAGCCAGGAATGTATCGG
+
+1;:B;;AAC?;:E@FEB;FFFF<G?FGIFCFCG@GFFACFFCF>D?D</?./=38=@@CFDF@@C37=A3@?(7;;6AC@?BBB?B@BB?<5:>@@(4<B
@1VC
ATTTGGTGTTGATGATTCTTATTCTGAACAAGGAGCACAAGACAGTCCGACTCATCTAGAGATGATGGAAAGTGAGTTGGCTGGGAAGCAGCATGAGATTG
+
CCCFFFDDHHHHHJIJJIJJJJJJJIJJJJJJIIJIJJJJJJJIJIJJIJJJJIJIJGHHIEIIGGIJHHHH;BDFEFFDDEDDDDDDDDDDDDDDDDDDD
@1VD
ATTCAGACTAGAAGCAGCCAAAGATGATTATCGAATACGTTGTGAAGAGTTAGAAAAGGAGATCTCTGAACTTCGGCAACAGAATGATGAACTGACCACTT
+
@CCFDFDFHHB?HEBDHEHHHIBDHHHH@?HHHDHGHGICFHIGDG<?BFHGGIGHBCFACAGGGIEIGGGFEFCDDBDCAB?CCD@CCDCDDCCCCCDCC
@1VE
ACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGC
+
@@@DFFFFGHFHHEDHHIGEGI?HGII@GGICHIIIDHIIIIIEIIIGFH<FH@GHEGIFIGHIH@DHDHHHFDBFFFECCCECAAA?CBBAB<AAB0<AB
@1VF
CACAGACCTCTGATGGACAGCAGATACTTGTGCCCAGCAATCAGGTGGTCGTACAAACTGCATCAGGAGATATGCAAACATATCAGATCCGAACTACACCT
+
@CCFFFFFHHHHHJJJJJIJJJIJJJJJJJGIJJIGJJJJJJJJJBGHFHIDFHJJJJJJJIIJJJEFHFGFFFFFFFEEEDEDEEDDDDDBDDDDDDDDD
@1VG
CACAAATTCGAGCATCACCTTCTCCCCAGCCCTCTTCACAACCTCTCCAAATACACAGACAAACTCCAGAAAGCAAGAATGCTACTCCCACCAAAAGCAT
+
??@DDDDDHHBFHGIIIII@@EBHHGGGIIGIIIEHDHGGGIIGIICHHIIEDHIIGHIEHGGHIHEHEEDEEEDCCCCCCC@CCC@AACB=BBBB?19A
@1VH
CCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAAC
+
CC@DDFFFHGFHHIDGGIIIJJIJIGIJJCHJJGIJIJJJIJJGGGIJIIIIJGFIGHIIFGHIGHHHFDDDFFEEEC@C@>CCCDCCDDAAC@CCDDDD
@1VI
GTGGCAATTCCTCCTGGAGCTGCTCTCCGACAGCGCCAACGCCAGCTGTATCACCTGGGAGGGGACCAACGGGGAGGTCAAAATGACGGACCCCGATGAGG
+
:==A1=;+<47<??7ABAA>+@;+32?;AA=A?):40=<AA':6A<;AAA>).)73;><;;=677'59=(8;;=05&+(+388(+4(850&&(+5&&53:?
@1VJ
GTGGGAATGTCAATTACGGCTACCAGCAACAGGGCTTGCCCTTAGAAGCCGCTACTGCCCCTGGAGCTGGTCATTACGAGGATACCATTCTGAAAAGCA
+
B@@FFFFFHHHHHJJJJGGIIJJIIJIIJHEGIJJJJJIIGGGBIGHGICGEHGGAEFEADFEFEECECD;@CCEDCBDDBDCDCDDDDCEDEDDDCBD
@1VK
GTGGGCTTGTTTCCATCCTGCGGTCTTGTAGGTGCAGTGGCTGCTGGCTGCTGCCCATAGGCTGGATAAGCAGGCTGAGTGCCATATGCAGACTGAGCTGC
+
@@@FFFFFHFFFHGIIIJJIIIE@GGHIJIJJFHGGGGHGHIJIJJJJIIIGCHIIAEHGCHHHFB>@C@CCCD;AD?B;ACCCCCDCC;A>AD::>ACC?
@1VL
AAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGG
+
@@@DFFFFHGHFFBHIIJJAFHIJJJJIJIIGHHJJJIJGIJJIIIGIJJEIIJJJIIIJJIGGEGFFFFDEEEEEEEECDDDDDDDDCDDDBDDDCDBDB
@1VM
GTAATAATGCCCCCCTCCCTCGAGCCCTCCCTTCCACATGGATTGAAAACAAACTCTATGGCATGTCAGACCCGAACTGGCCTGGAGAGAGTCCTGTACC
+
@??DDFFFFDDDHH<@FHGIIIDFBHEEFDBHGGFBFH@FHHIIIIGGGHECE?=ADBDFEAE;>AA;>@>AB@@BBACC?BCBC@<9<<2>@A::+:@C
@1VN
TCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCC
+
@@@BDB?DFAFDDEHIGHDHE?EHBFGIGBCC<8?DBCGHD:FHE@BFHGGEGGDDDEHI7?EEEHHHE;;BDFCCAECCC@CCCCC<<C@@?<<<CCBB
@1VO
TGAATGTTAATTCTTATACCCCCCAAGGAGAAGGCAGGGTGGATCCTGATCGGTCCAAGCCTAAAAACCTTGCTCCTTGACAAGAGAGCCATGAGACTTAC
+
;95898@4):))6:84=))..((:>31971(9)(.<=88.747).3=;)8)('--59)),(.:;;19'7;<5:75(3;(:5=(+(++2(+((+25(+(4(5
@1VP
GACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACAC
+
CCCFFFFFHHHHHJIIJJJJIJFHIGJJJJJJJJJJJIIJIJJJHHHHFFDDEEEDEEDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDEDDDDD
@1VQ
CTCTTCACAACCTCTCCAAATACACAGACAAACTCCAGAAAGCAAGAATGCTACTCCCACCAAAAGCATAAAACGACCATCACCAGCTGAAAAGTCACAT
+
CC@FFFFFHGHHHJJJJJJJJJJJIJJJJJJJJIJJJJJIJIIIJJIJIIIJHJJJJJIJJJJIIIIGHHGHHFFFDDDDDDDCDDDDDDDDDD>CDDDD
@1VR
CTGTCATTCACCCTCAATTTCTGGCAGATCTGCTGTCCCCAGAAAAACAGAGAGATCCCTTGGCCTTAATTGAGGAGCTAGAGCAAGAAGAAGGACTCACT
+
@@@=D:B?FDDDFHGEBEHIEGG@CCFDABBEHCHFHCCHFHGIIIIIIFHI;BGHBGHGICDEEGEHGE>=CHF@BB@CCCCCCC=;A>;??2<BCACC:
@1VS
GGGTGAGGGAGCCTTTGGAAAGGTCTTCCTGGCCGAGTGCTACAACCTCAGCCCGACCAAGGACAAGATGCTTGTGGCTGTGAAGGCCCTGAAGGATCCCC
+
?<?4AAA;FHFAD;F@GG<AAC3FBEB?*:EGI;):800?FFH*/8-.B<FH;5/5:?8.6;66555?>35>>>9:?(5+(3+4(((++8?3:(3(49(3+
@1VT
AGCAGCTCAAAGCCGTGCACGAGCAGCTTGCAGCCCTCTCTCAGCCCCAGCAGAACAAACCAAAGAAAAAGGAGAAAGACAAGAAGGAAAAGAAAAAAGA
+
CCCFFFFFHHGFHJJIJJJIIGHGGJJJJJJJIIJJJJIJGIJJJJJJJJJGIJIHHHFFFFFDEEEEDDDDBDDDDDCDDDDDDDDDDDDDBDDDDDDD
@1VU
CACAAAGCCACAACTGGCTATTGTTACCCAGTGGTGGGAGGGCTCCAGCTTGTATCACCATCTCCATATCATTGAGACCAAATTTGAGATGATCAAACTT
+
@<;DDB:BF;<C?:CGI;CH@HH?AFB9<EGF>;FD)?F1)(7(.<F=F)@@=7@E:E;D?>7))=B;BB777>AC;;;;?;5;AB:89::(,>A:444:
@1VV
GTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACA
+
@@@DADAB::DDH=CCABFDFB<<?BECG;DHGHGIIGIEFHCHIGIAHE8DGD=CCDG=FHE3CDEHHA;?@D=BC>BC???C@BBBCC>C@CC?CCC
@1VW
GCAGATACTTGTGCCCAGCAATCAGGTGGTCGTACAAACTGCATCAGGAGATATGCAAACATATCAGATCCGAACTACACCTTCAGCTACTTCTCTGCCAC
+
CCCFFFFFHHHFHJJJJJJJJJJJJJFGIFHIFHIJIIJJJJIEHGIIIJIGIJJIJJJJJJJIJJJJJHHHHFFFEEEEEDDDDDDDDDDDDDDDDDDDD
@1VX
ACCATGCCTCAGGAGGTCAGGGCAGCCAGAGAGGATCCCAGCTGCTCCCTGCTGGAGCAAAAGGCCCCGGCAAACTTCCATATCCTGTTGCCAAGTCTGGG
+
@@@DADDDAC>>;EFFAEEFEF;G:EGGIF31?)0:DDC9*)09?3BFFCF@@7@@CD;7>7A12?=9',38?B?:((>:B(:4:44>@@:>>38:>::??
@1VY
CGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGG
+
@@@DB<;DFFFHFGIIIIGGEDH@FGGG@GHGFDF?FGGGGIACGDF@HBGCD@FEGGGE=AA?AEDD@DFECC@=?=@ABB@CCC>>CCCCCC3:CC><B
@1VZ
CGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTCCACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGG
+
@<;DDD;:AF?DFEG9EF<F:E@GF?BGC+<:8CDF>F?6;/9)8=CFFFB)=)@D;BA88B>;?;?B3>B;A@B:(>(5>3<:8?B?@BB???@B>@DBB
@1W0
CACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGAT
+
C@CFFDDDBFHHHHHIJIIGEHIIFHIHGIJIJJIIDFGGGHEHIGHHEGIIE@HGGGJIIIGFHHFFFFACCEDDCDDDDCDECDCCBDDBDDDDDDDDD
@1W1
GGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACAC
+
CCCFFFFFFHDHHJIJJJJJJJJJJJJJ9FHHGGIGIJJGHIJJCHHIJIGIJHICGGIGIIGHJGIJGHHHGFFFFDDCEEDDDDDDDDCDEDDDDDCD
@1W2
AGGAGGGAGACTGGAGCCACCAAGAAATTGTCCTGATGATCTGTGGAATTTAATGACCCAGTGCTGGGCTCAAGAACCCGACCAAAGACCTACTTTTCAT
+
;?@?D?:<8C;CBE3ACGFEAFIE3::CFFGCBGDG9F?D*9D9B;?FFBFB4BCF@==;6=@=DCEFFFDDDDDCC@998?B?99?B@?@@9:>>@>BA
@1W3
AGCAGAGGAAGAGGATGAGGAACTCTCCAACTTTGCTTACCTCTTGGCCTCTAAACTTAGACTCTCACCAAGGGAGCATCCCCTCAGTCCTCACCATGCCT
+
@<@D?D?DDHH;C;FBADHBFC?CECF9EAC>@9?FFDFBDD*:?DF;BDECF?D=BGI>).>7=CE:@=6A;5A',6;>6(=A8A?C@C;::9<3:ACAC
@1W4
CTGAAAAGTCACATAATTCTTGGGAAAATTCAGATGATAGCCGTAATAAATTGTCGAAAATACCTTCAACACCCAAATTAATACCAAAAGTTACCAAAACT
+
@C@DFDFDBFFDDHEIGGCHGIJGEFIJGIBHHIIIJGGGGHGDHHEGHCIIFEE@GHIJIIIIGGGGEGHDEHDE@DECCEAEEC@BACCC@C@CDDBDD
@1W5
CTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTT
+
?;?BDDDDHHGGFIJIHGHJDHIIJIJJJIJJJJIIJIH>?DFHEDG>BDBFCHHGBH@EGHGHBEBDCEDCE@CCCCDDCDDDA@C899AAABDBBDB>A
@1W6
TACCCCCCCTGCCTCATTACCTGGCTCACTAACTAACGTGAAAGCCTTACAGAAATCTCCAGGACCTCAGCGAGAAAGGAAGTCATCTTCATCCTCAGA
+
@@@DDFFFHDBFHBGHEGHIJJJJJJJJGJIJJEGIBH=28@FGGGGHGEGHEGHCEFFFEFFDDDCCCCCB?BDBDDB?CB:@A>@CDEACCCDDDC@
@1W7
AAAAAAGAAAAGCACAAAAGGAAAGAGGAAGTGGAAGAGAATAAAAAAAGCAAAGCCAAGGAACCTCCTCCTAAAAAGACGAAGAAAAATAATAGCAGCA
+
@@@FFDDFHHHHHJIJJJJJJJJIJIJJJIJHIGHIIIJIJJJIJJJIJJGHHHHFFFFDDEEDDDDDDDDDDDDDDDDDDDDDDDDDDDDDEEDDDDDD
@1W8
ATAAAGTTAATGAATGTGGCAATAAATGAACTGAATATAAAATTGCAAGATACTAACTCTCAAAAGGAAAAACTCAAGGAAGAACTAGGACTAATTTT
+
??<B;DDDDDD4C::CEE93CEFEEAFEFCEAFII4EECEEI<@@DCEE@DEE>D4?D>D<<DEEE;88=7=@C;C>AADD(.;3.;>>>AAAAAADA
@1W9
CAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAAC
+
<??DB;D?DACBBGGGIIDE@FHIIGIIIIIIDHGIEGG@FFGGEHIIIBEIGCHHCHGGIIGGHFCEEEEC>@BC>CDCCCCB?ABBCCCCBCBA5>CCC
@1WA
TGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGG
+
CCCFFFFFHFHHHJJJIJJJJJJJJJJJJJJJJJJJJIJJJIIIJJJJJJJJIJHIIIIHHHHGHFFFFFEEEDDDDDDDDDDDDDDDDDDDDDDCDDDDD
@1WB
CTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTAC
+
?@;+A2==D;CDBG@BFGIGHHDHBFCHFF9)::)08BAFF=F=B@DFI957?A>ECEDB@DB@?@>>;AB>A<>;(;;;5:@?B88:@@AB>@@1+58@B
@1WC
GGAAAGACTCAATCAATCTGATTCTATAGAAGACCCTAACAGTCCAGCAGGAAGAAGGCATTTGCAGCTCCAGACTCAATTAGAACAGCTCCAAGAAGAA
+
CC@FFFFFHHHHHJJJJJJJFIJJJJIIIJJJJJIJJJIIJJIIJJJJJJGIIJJJJJIJJJIJJJJIIIJJHGHHHFFFFFFEEEEEDDDDDDDDDDDD
@1WD
TGATCCGCCGCCTCTCCCCGGCTGAGAGAGCTCAGGGACCCAGGCCGCACCAGGAGAACAACCACCAGGAGTCCTACCCTCTGTCAGTGTCTCCCATGG
+
??7;DD::2CDADIE3<EE8):@69B<@(7BBBB>)=C=C166;?CD<>3,(,8?5925,52280((+(2+9AAA(+(++89(:::>(4>>>>AA9>((
@1WE
CAGGAAAACACGACATGTGAATATCCTACTCTTCATGGGCTATTCCACAAAGCCACAACTGGCTATTGTTACCCAGTGGTGTGAGGGCTCCAGCTTGTATC
+
@@@FDFFFHHHHGJJJJGHHIJIIJIIIJJJJJJJJFGIJIJGIJJJGIIJCBEHIGGCHIJJJ>EHEHHHHFFFFFCE>?6=@CBDBADDDDDDDDDDED
@1WF
CCTTGATGTGTTAAACTATGTGCAATCAGGAGTGATATTGGATCCACCAATAAATTTTTTTTATTATTTTTTTAATTTAATTATATTTTTTTTTTTTTTAT
+
(07934@14122:)<):)3)3;?1.)).3<.22(.)1)2)9;1)).)(.0).))09)9.'-'(8)).))))'',-:(3(,:(((,(,(,(&5005-0)&((
@1WG
GTTTGAAAAGGACAATTTGATAACTAAGCAGAATCAATTAATTTTGGAAATTTCAAAGCTAAAAGATTTACAGCAGTCTCTTGAAAATTCAAAGTCAGA
+
===?<++?<7AABB=BB,<C<A@BBBBB9BABBB?ABAB?=<7:A?<B?B=<=?BBAB>BB=>A>;=78./>A3.6=7=)7=;)7;>9;>@@;>>?=??
@1WH
GAAATGAGAAGGGGGAAAAAAATTAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
+
+1++222+>?+2))))22)?)0)***07*'5'',',7;111-775-555::::77/79;;;;;7;7;;7;;;=;-05;;;;9;955-5599;;;.59;93
@1WI
TCCATTTATATGAGGCAAGAAGGCTTCCTGGCTCATCCCAGCAGAACAGAAGGCTGTATGTTTGAAAAGGGCCCCAGGCAGTTTTATGATGACACCTGTGT
+
?@@=BDDDFHFBHGGIIIIIIGAGIIGIGGIIGHIIEHIEDGHCHGC@9?FH@GEGBG<FHIGHIIFEHIDEHDDCCC@B@ACDCC@CC@>@>C>@?>CCA
@1WJ
CTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTAT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJIJJJIJJJJJJJJJJJJJJIJJJJJJIJJJGHHHHHFFFFEEDEECDDDDDDDDDDDDDDDDDD
@1WK
CGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCG
+
?@@DFFDDHFHHHJJJIAGIEGIFHIGGHHIIIIJ4BFIGFHGGIHHFFFFFDEFECEEDCCDDDDDDDDDDDDD@BDDDDDDDDDDDDDDCDECDDDDDD
@1WL
CAAAAGGCCGGTGTTTGCGGACATCAGCAAAGACCTGGAGAAGATGATGGTTAAGAGGAGAGACTACTTGGACCTTGCGGCGTCCACTCCATCTGACTCC
+
+:84=+2A?)@CD@29ACC8):0B9D?*9B80*0/.=.B@DC@77=C=@;7=CCDDD;@=@@>6->A>A>5,><5555'0&00)5+++99:+>4+:A4::
@1WM
TAGAAATCATTATTAACCACAACAGGGCAGAAAATGTACAGTCATGTGATACTCAAGTAAGCTCTTTATTAGATGGAGTTGTGACTATGACAAGCAGGGGT
+
CCCFFFFFHHHHFIJJJJIIIIJJJJJIIJJJJIJJGGIJJJJJJIDHEHIJJIJJJJIJJIIJJJJIIJJJDHHIGHHEHEEFFFFFEECEEEBDDDDD;
@1WN
TGGACTTGGCACTTTTGAGCGTGGAGTAGGATGCCTGGACTTTTCAAAAGCAGATTCAGGTGTTCATTTATGTGTTATTGATGACTCCAATGAGCATATGC
+
CCCFFFFFHHGGGJIJIIDGIGHIGH?CGH@FHHGIJIIJIJJIHGGIJJIIIHIJJJJJ=CCHGGHHHCHG?EADFDFFFEEDECCEDDDDDDDDDDDED
@1WO
CCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACA
+
?;?D;BBDCDC=+81C@ECH@AE9?C*:CF<:D@FA>B<BB3BGGG>;89B3;3)=CF@2=@CCA49<?@@>(5;;@BBB<(9?9(,,55:44+4+4:4@
@1WP
CCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGCATGGCACTGGTGCTTATGATACCCCCACTGCTACAGTCACCACCACCCAGGCCTCCTATGC
+
@@@DDDD:C3CFFE8CF;C@??<FGEFGIFI?<BDB@@6'7=A(=@>D>E=3?A>=B?>))7>(63'',(>>>A>@;>>>A>@??BB<B808?A8?@B:AB
@1WQ
AGAGGACAAGTGCACGCCTATGTCCTATGAGGAGAAGCGGCAGCTCACCTTGGACATCAACAAGCTCCCCCGCGAGAAGCTGGGCCGCGTGGTGCACATC
+
=;=A;A==732<7,+<??=<@A<<+7?A<AA=@)1?:3))8=4(9>=)....7;>A>AAAA@<);(6>=:''8305-9((+33(22;-009;;9(+8(++
@1WR
AAAGAACAAGTTTCATTGAGATGTAGAGAGCTAGAAATCATTATTAACCACAACAGGGCAGAAAATGTACAGTCATGTGATACTCAAGTAAGCTCTTTATT
+
@C@FFDFFDFFFHIIDGDBHEH@<BHIGC@GHHEHHEGFGHIIIIAFGFDHIG;??DA;BFCGHHGG7CCHD;AHHHCEEDFFFEFEC>AE:AACC>ACCC
@1WS
CTCCGCTATTACTATGAGAAAGGAATTATGCAAAAGGTGGCTGGAGAGAGATATGTCTACAAGTTTGTGTGTGATCCAGAAGCCCTTTTCTCCATGGCCTT
+
CCCFFFFFHHHHHJJJJJIJJJJJJJJJJJIJJJJJJFHIJJJJJJJJJJIJJJJJJJJJJJJJJJJHHFHHFFFFFFEEEEEEDDDDDDDDDDDDDDDDD
@1WT
CCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTAT
+
C@@DFFFFGHGGHJJJJJIJJIIJJJJJJJGIJIHIJJIJJJJJJJIJJJIHHDFDFFFEEEEEDDDDDDCDDDDDDDDDDDDDDDEDDDDDDDDDDCDDD
@1WU
TGGCCAGGCGCTGGGGCGAGCGGAAAAGCAAGCCCAACATGAATTACGACAAGCTGAGCCGGGCCCTCCGTTATTACTATGATAAAAACATTATGACCAA
+
1:=DDAD?FFFH61;:?:6?F8F<A6AAA3;@(;;6=A(;@CC@;:51<=@B?83(:8>?BBBBBBBBBB?>?BCD>:@BC@4@@A>39?::CDCA:@CB
@1WV
CTTTATCCTGGAGCTGCTGCGGAAGGAGGAGTACCAGGGCGTCATTGCCTGGCAGGGGGACTACGGGGAATTCGTCATCAAAGACCCTGATGAGGTGGCCC
+
CCCFFFBFHHHHHJIIIJIJJIGIGIJJICGBDGHGIJHIJAAHIIGIJJHHHHFFDDD?BDDDDDDDBDDDDDDBBACDDDDDDDBDDCCCCCD9A@BDD
@1WW
AGGCTGTATGTTTGAAAAGGGCCCCAGGCAGTTTTATGATGACACCTGTGTTGTCCCAGAAAAATTCGATGGAGACATCAAACAAGAGCCAGGAATGTATC
+
?@@DDDDADFA?AFHIFGEFHFGIIIIGIIIHIIIIIHIIFGHGGD>CF3DF=B==FHIIGIEGICHCAEH8BB;?;A@@CDCDD=C9ABC???BA>:@CD
@1WX
CGGTGGATGGCTCCAGAAAGTTTGATGGATGGAATCTTCACGACTCAATCTGATGTATGGTCTTTTGGAATTCTGATTTGGGAGATTTTAACTCTTGGTC
+
=;=2@0A8AA2<+2+<A3A++?>A>A@BA=A<A=B>AB<AB)1=<ABBBBAB<)9/9=>A=>A;;ABABA3.=AA)77.>@@;=9;==;;=?>?9=?>;9
@1WY
GCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGG
+
@@@FFFDDHFHHHIG?DBDFBGFHGBCDHCGGEA>EGIG:D@FHIIIG=CEH6?AHEBFFFEEACE=ACB?>5;>ADCCCCC@;@CCCBC??+>:@@CBB
@1WZ
GAAAGACAAGAAGGAAAAGAAAAAAGAAAAGCACAAAAGGAAAGAGGAAGTGGAAGAGAATAAAAAAAGCAAAGCCAAGGAACCTCCTCCTAAAAAGACG
+
CCCFFFFFHGGHHJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJGIJIJJHHIGIIJHHHHHHFFFDDDBDDDDDDDDDBBDDDDDDDDDDDDDDDDBDD
@1X0
AATCGGCTCTGCCTGCAGTCAAGAACAGCCCTTTAAATTCAGCTATGGAGAAAAGTGCCTGTACAATGTCAGTGCCTATGATCAGAAGCCACAAGTGGGA
+
@@@FDDDDHHHHHGEIJJJJJJGHHIIJJJJIJIIJHIJIIJIJJJJJFGHIGIGFFIGIIFHGGGJIJJIGHFHGFFFFFFDEEEEEEDDDDDD>CCDD
@1X1
GTTTCTTTTGAAAATATGACTGTTGGAGAAGAAAGTAAGCAAGAACAGTTGATTTTGGATCACTTACCATCTGTAACAAAGGAATCATCACTTAGAGCAAC
+
@<@DDDFFDFDFFIIIIGHIIIC>HHGHGEIGIIIIIIIIIIGIGIGCGAGGGBAGGIGHGGGGGGGHIIIAE@CDHHHHFC@DFFA@CC@ACCA;>@C?B
@1X2
CCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTTATGGG
+
CCCFFFFFHHHGHJJJIJJJJIJJJJIJJJJJJJJJJJIIJJIJIIJJJIJIJJJJIIIJJGHHHHGFFDDCDDDDDDDDDDCCCACEDDD9<>BDDDDDD
@1X3
TTCTGAACAATTGAAACAGAAACATGGTGAGATTAGTTTTCTAAATGAAGAAGTTAAATCTTTAAAGCAAGAGAAAGAACAAGTTTCATTGAGATGTAG
+
+::?AA,+?AAAC?BB>@BBABAACAC?AAC?A<AB4474*:?AABAABBB>B?4=AA<47AAAA>A4>ABBBBBABAA)=AA);?????>>@@@;5;=
@1X4
AGCGAGGGGGAGACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTAC
+
@@@DDD)<FHDFHIIJIEHFHGGIGHDGHIIIHFFF;@CAEDDDDDCDCDDDDBDDBDDDDBDDDDDDEDDDDDDEDDDDDBCDDDCCDDDDDDDDDDBDD
@1X5
CAGCCATTCAAGAGCTGATGAGTAAAGAATCTCCTGTCTCTGCTGGAAATGATGCCTATGTTGACCTTGATCGTCAGCTGAAGAAAACTACAGAGGAACT
+
CCCFFFFFHHHHHJJJJJIJJJHJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHHHHFFFFFEEEEEEDDDDDD
@1X6
CCATGGCCTTTCCAGATAATCAGCGTCCACTGCTGAAGACAGACATGGAACGTCACATCAACGAGGAGGACACAGTGCCTCTTTCTCACTTTGATGAGAGC
+
@@@DDFFFDFHHHGIBEHIIIIJIIGDFHGEEH@GCGHIIJDGGGIEGHDCFFFHGHHIIIIGGFHHFFDACEDDCDCDDDDDDD>CDDCDDDDDDDCCCD
@1X7
TTCAACCACAGCAGATGACTGCAGTTCAGAGGTAAATGGTTGCAGTTTTGTGATGAGAACAGGAAAGCCTACAAATTTATTAAGGGAAGAAGAATTTGGTG
+
<@@DFFFFHHGHHIIIIJJJIJJJJIHJJJJIFGIDGHIHGIHGIGGGJJHGHIIFDGGGIIIGIGGJJJJDHCEHHFFFFFFFEEDCDDDD?CCDCDA<@
@1X8
GCCACAAGTGGGAATGAGGCCCTCCAACCCCCCCACACCATCCAGCACCCCAGTGTCCCCACTGCATCATGCATCTCCAAACTCAACTCATACACCGAAAC
+
===AAA;@2<<A=>++<=@AA72<AA*:1=?=8:A:(;<2))6>A37=(591;6;5;=;=5;=(93;9;=9,53:3:(88;8(:38;??3;3:8=;95.5;
@1X9
GGAAGGACGTCCTATGTACCAACGCCAGATGTCTGAGCCAAACATCCCCTTCCCACCACAAGGCTTTAAGCAGGAGTACCACGACCCAGTGTATGAACAC
+
<;?B=1;DAHHDFBFGHGC@CHIIGGGIDGAFG<G9<FFHDHGGIFGGG;@CHHGH>EHEHFDBEECCC<A<A=@@,:>CC:?BBBBBB>@>>>CCEAAC
@1XA
ACCTGGCTCACTAACTAACGTGAAAGCCTTACAGAAATCTCCAGGACCTCAGCGAGAAAGGAAGTCATCTTCATCCTCAGAAGACAGGAATCGAATGAAA
+
@@@B?D?DABBD<EG?@GCHAC@;EAFD?C<FBFHDA?B?B<9BB@D;BDFB9F@@8ADCG=CHACAEDE>;;;?@;@@@C;55;;;?B?:59(>CAA@C
@1XB
CCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGAGCTTACACCGCACAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTAT
+
@81AA4,:CDFFD@>FGFF6?@F<?1):6):)?D*0BGI>38B8'-'-5)6?;(,;;;@;>@>>;5555>3>?BB98@B<@B<:+:>>?B@<?B?@A34@B
@1XC
CACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGT
+
CCCFFFFFHHHHHJJJJJIIIJJJJJJJIIIJJIJIJJJJJJJJJJJIJIJJJIJGIJJHHHHHFFD=BBCDDDDDBDDDDDDDDDDDDDDDDDDDDDDDA
@1XD
TGCTTCCTCAAGGGAAGGAGCCTTTAGCAGTGCCCTGGGAAGGCTCTTCAGGAGCCATGTGGGGAGATGACAGAGGTACCCCCATGGCTCAGAGTTATGAT
+
@@;DDDFFDFHFFEHIBGGIIIIGIHHIIIGHEGGGIEIIIIIIGIIIIIIIGGGGHGI@DGHHHFBCCAE@@ACB;AACDDDDDCCBCCCCC:>@@D@>D
@1XE
AGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGAT
+
CCCFFF?EHHHHHJJJJJJJJJJJJJJJJIIJJJJJGJJGIJJJJJJFGIIIIIIGIHHHHHFFFFFFCDECDDDDDD<BDDDDDDDBDDDDDDDDDDDDD
@1XF
CTGAAGTAGGAGATAATTGGAGGCTAAAGATAAGCAATTTAAAGAAAATTTTAAAAGGAATCTTGGATTATAATCATGAGATTTTGGGACAGCAAATTAAT
+
@@CFFF=DFHHHHIJJJJIJIJJIIEFEHIIIEHIGGHJJJJIIFJIIGHJJIJJGGDGCGHEIGIGIGGIIJHEIFHCEEHHFF3=<;>BDBCDDCCCDD
@1XG
CATCACTTAGAGCAACTCAACCAAGTGAAAATGATAAACTTCAGAAAGAACTCAATGTACTTAAATCAGAACAGGACTTGATTAGAGACCAAGGATTTCGT
+
CC@FFFFFGHHHGJJJJJJJJJIJJCHIJGIIJJJJIJJJIIJIJJJJIIIJIJJJJIIIJJIJJJJJJJJJJJJJHHHHHHFFFFFFECDDDDDDDDDD?
@1XH
GTTTCGCCGGCAGTCTCGATGATAGTATTTCTGCTGCAAGTACTTCTGATGTTCAAGATCGCCTGTCAGCTCTTGAGTCACGAGTTCAGCAACAAGA
+
@CCFDDFFFFDDDIGGIIEGHGIGHFIIHIIGIJGJGGHGBFFGGGGHFFHEHEGHIJJJGEHEFDFFBDCECEDCC@CCCB@=?@CDCCCDBB@DD
@1XI
GACCACGCTTTCCCCAAATTCTCGCCTCTATTGAGCTGCTGGCCCGCTCATTGCCAAAAATTCACCGCAGTGCATCAGAACCCTCCTTGAATCGGGCTGGT
+
?@@DDB+@FB?ADE?F?FBA?CEE?FD?:?B:*0000?;F9D?BF;F8;ECEIC@===ABD@@?@;53,;5@C3>:>CCCCBBB@??AACCCC8&5<5<B3
@1XJ
GCTCCAGTGAGTCCAGCTCCTCTGACAGCGAAGACTCCGAAACAGCATCTGCATTGCCGGGACCGGATATGAGCATGAAACCTAGTGCCGCCCTGTCTCC
+
@<=?DD>DH?FAFHGE@EBGHDHIGEGIGIBGGAGIHIBDHIGIIG@DA@GCGCHDGHHHE49=>BBD;>ACDC@@CDCC>ACCDACCCDBD@BBCA:>:
@1XK
CGAGAGGGAGACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTAC
+
;?@FDDFFHHHHHJJJJIJJIJJJJJJJHIJIJHHIIJIJIIHEHHCEFFFDDDDDDDDDDDDDDEEDDDDDDDDDDDDDCDDDDDDDDDDDBDDDBDD
@1XL
CTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCT
+
@@@DD++=CFFAF1@E6@FF9:?CGB@CDBBG;::?@9BD@?/??BFEFD8F;F==@@D=@CAEE@6??;@CCCB?>>5;@ABBA?=;><<@B@ABA>ABB
@1XM
GAAAAAAGAAAAGCACAAAAGGAAAGAGGAAGTGGAAGAGAATAAAAAAAGCAAAGCCAAGGAACCTCCTCCTAAAAAGACGAAGAAAAATAATAGCAGC
+
@@@DDF)<<DFFHIBDGBDGDEIIG@BC=DAFDGI@GFGCBG@FDEHHEB<EEFFEFDDE==ACDDC?ACDCCCCCDD:?C@BB?@DDDDBCCEE@CCCD
@1XN
TGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTC
+
C@CFFFFFHHHGHGJJJIJJJJIJIJIGJGGGGIGEHIJJJJJJGJIIJJJIIGJJJGGAGEIGHFFDBCDDDDDDDDDDDDBDDDCDDDDDDCCD@CBDD
@1XO
CACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGG
+
@@@FFFFFDHFHFIIGIIHEHGGIIIJJHJJGHICHEIGIFGIIJEIIJJIGJGJIHGEHFFFFFFDCEAEEACCDD?<ABBDCAC>CDDCCD<@CDDCDD
@1XP
CTCAAGAGTAATAATATATTTCTTCATGAAGACCTCACAGTAAAAATAGGTGATTTTGGTCTTGCTACAGTGAAATCTCGATGGAGTGGGTCCCATCAGTT
+
===A+++<2?<<@@@?C43?AA7<,,@?@A7A37+?=AA>*:4**1:=AB0:?*9?A70A7=*9=>A47=AB;ABB47=AAA=A3A.5;;=>@=??>9>;=
@1XQ
CCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCAC
+
1??DDDDDBB?<<EDF?AHCDDG@DFGICFFGIEABB;?<BFFFCFBF=FFFDFIAEFFD5=BA;=BCBBBBBBBBBBB>AAA:@A?BBA>A@BB:::(::
@1XR
CCTGCGCATGAAGCTTCCCAAGCCTCCCAAGCCTGTGAGCAAGATGCGCATGGCCACCCCGCTGCTGATGCAGGCGCTGCCCATGGGAGCCCTGCCCCAGG
+
?@8AAADDFFCFDICDBGGGCF@GHHIIIGGIGEGGBGGCCHIIGB=;FG@FHEHHHE8B9A/3;A@CCCCC:9?8>@@<?BC39>AC?@?@((+<<?B??
@1XS
CACCTTCTCCCCAGCCCTCTTCACAACCTCTCCAAATACACAGACAAACTCCAGAAAGCAAGAATGCTACTCCCACCAAAAGCATAAAACGACCATCACC
+
CCCFFFFFGHHHHJJIJIJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJIJJJJJJIIHHHHGHFFFFDDDDDDDDDDDDDDDDDDDDDDDD
@1XT
CAGAAAATGTACAGTCATGTGATACTCAAGTAAGCTCTTTATTAGATGGAGTTGTGACTATGACAAGCAGGGGTGCTGAAGGATCAGTTTCTAAAGTAAAT
+
CCCFFFFFGHHHHJIJJJJIJJJJJJJJJJJIJJJJJJJJIJJJJFIIJIJHIIHIJJIJJIJJJJJJJJJIJEHHFFFFFFECEECEFEDDDEDDBCDDE
@1XU
AAACAACAGATCCTCACTCATCAACAGCAGCTTGAAGAACAAGACCACTTATTAGAAGATTATCAGAAAAAGAAAGAAGACTTCACAATGCAAATTAGTTT
+
C@@FFFFFHHGHHIJJJJJJJIIIIJJJJJIIJJJJJIIJIJJJJIFGIJJJJJJJJIIFIJJIIIJIJJJHHFHFFFEEEEEEEEDDDDDDDDDDDDACE
@1XV
TGATCAGAAGCCACAAGTGGGAATGAGGCCCTCCAACCCCCCCACACCATCCAGCACGCCAGTGTCCCCACTGCATCATGCATCTCCAAACTCAACTCAT
+
CC@FFFFFHHHHGJJJJEHHIHIJJIJJJJJJJJJJJJJJJIJIJHHHFFFFFDDEE@BDDDAD@CCDDDDBCDDDDDDDDDEDDDDDDCDCD@CCDDDD
@1XW
GCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGC
+
CCCFFFFFHHHHHIJIJIJJIJJJJJIJJJJJJJJJIIJJJJJJJJJJJJHGIEIJJJJIHGHGHHGHGFHFFFFFECEEECEDDDDDDCDDDDDDCCDDB
@1XX
CCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTT
+
CC@DDDDDFFHAFHGGIICGGIHHIJIICHIFIJJJGJGIIJJIJJJIJJIGIJJI=FGIIJJHHHGGFFFFFEDCCEEDCCCDDDCBDDDDDCCDDDDDD
@1XY
CCGCAAAGTGGGGCCTGGCTACCTGGGCAGTGGAGGCAGCCGCAACTCCAGCTCCCTGGACCACCCGGATGAGCGGGCCCTCACCATGGGCGACCTCATCT
+
@@<?DD1B<CB;CGA?CADAGEFGGF@3B@GGG9@F;6?B;F<4;@HCA;??DD@=>>?A?C9?@@BB?9;A>:59@359888?B>(:><@>0059:CCC@
@1XZ
CAAAGAGGACTTTCGCTATCGATCTCCTCATTCAGGTGATGTGCTCTATGAACTCCTTCAGCATATTCTGAAGCAGAGGAAACCTCGGATTCTTTTTTCAC
+
???DBDD?+ABDD?E@AE1CEDDEDIIDI<DDDEDC?D*??BBDDDDECDDDD?DBC>8==AA)8AE@ACDEDDDD;C@@27;>;;>?6??AADAAA>AAA
@1Y0
CTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACC
+
@CCFFFFFHHHHGIIJJFGIIJJJIJIJJJIJGGIIIJIJJIIIJJJJJJJJJIGHHHHFFFFFFEEEEEDDDDDDDDDDDDDDBBCCCDEDDDCCDDEDD
@1Y1
CGGATAATGACTCAGTGCTGGCAACATCAGCCTGAAGACAGGCCCAACTTTGCCATCATTTTGGAGAGGATTGAATACTGCACCCAGGACCCGGATGTAAT
+
?@@DFFBDHAFAFGGCF@FHGEGGIGIGGIIIIIGGEGHIIIIIIGHIIIIIIGF<CHGGGGHIHG>CEEACFFFDFEEEBCCCCBBCCBBBBB59@@DDC
@1Y2
AGCAAAGGAACACTTTTTCATTTGCTGAAAAAAACTTTGAAGTTAACTATCAAGAGTTACAAGAGGAGTATGCTTGCCTTCTCAAAGTAAAAGATGATTT
+
@@@?DBDBBFFD?GGGHIGEG<<BFHGIGEEGBHGGDIEGGG?DHIG<DFIAHFFFF@C@F>@A>6?C?A@?7;?C?C;;A6;ACC>;5>@A:,5@A>@C
@1Y3
CATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATAT
+
@;@?DDDDDDB1D9FHB<B@DD@F@GIFIGEIGH?BDDGBDFCGIG9?FGG=FGDGGDGC=CCEDEHHHHBDEB@CACBBCCAC:AC@?>ACCCCC@(>:A
@1Y4
CCGCCTGATGCTGCAATGCTGGAAGCAGGAGCCGGACAAAAGGCCGGTGTTTGCGGACATCAGCAAAGACCTGGAGAAGATGATGGTTAAGAGGAGAGACT
+
@@?DDFFFHFHHHIJEGIIIJIJJJIJJIJFEGIIJGGGIGHGIJJJAHBEEFDFC>BDD>CDCCDCDCDDC?B<ADDC?>CA@CCCCCCDDCDD@?BD?C
@1Y5
TTGAAATCGACTTTGAGACCCTGAAGCCGTCCACACTGCGTGAGCTGGAGCGCTATGTCACCTCCTGTTTGCGGAAGAAAAGGAAACCTCAAGCTGAGAA
+
;<?DD>?DHHFFBGFD:CEEGGGHG<?C@8??DFBBBDBD?@FHG<DGEGEHEEE47;BCDC>BC>CC@CCCBBBBBBCCCC@BCCCBAC@CACCCCBCC
@1Y6
CCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTAT
+
;375>:>>>????<:<<<<??(8=(8:9??<<8=:38>;)=><5;8;;9>=<63=;0=;=>5(63(3-(-(-5;;<<7<<<3<6:2+69866(82876:6:
@1Y7
GATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCC
+
+1==:3+2ACDDDEEEEBF>43<++A?E@C9C?CE@D3D3B)08(7?=;))8@A>@@AD2@CC=).=@D)).73>>@>(>;5=(5>3(>9<<8<8828<9>
@1Y8
CAGATCCGTATCAGATCCTGGGCCCGACCAGCAGTCGCCTAGCCAACCCTGGAAGCGGGCAGATCCAGCTGTGGCAATTCCTCCTGGAGCTGCTCTCCGAC
+
@CCFFFFFFHHGHJIIJJJGHIGHIJFJJJJIJJDHIGJJJJJJJJJJJHHHHHFDEDDDBBDCDDDDDDDDDDDDDDDCDDDDACCBDDDDDDDDCDB@D
@1Y9
CATCTATAAAAATGATTACTATAGAAAGAGAGGGGAAGGCCTGCTCCCAGTTCGGTGGATGGCTCCAGAAAGTTTGATGGATGGAATCTTCACTACTCAAT
+
@<@DBDEFHH?AFHIGGBHIEFGEIGIGFEEFEHGHGDHGIIGICHGDHI=CCFH;@AG3=??EHB@?DEEC;;A@C;@CCCCBCCCCCC@>C@CCCCCCC
@1YA
CTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTAT
+
?@?:DDDD;?FB=A:@G7??FD??FACDAAD3?FHA@9BDHGEF;C@EGGIC)=:==7;)7?D;;@>?@BC@@;;:55;>@CA>??@?8@B<@@2@1?C>C
@1YB
CTCCTGTTAGCCAAGAAGAAAGATTGATTTTCTTAGACTCCATTAAGTCCAAATCCAAAGACTCTGTGTGGGAAAAAGAAATAGAAATACTTATAGAGGA
+
@@@<DDABFDH?F@A?<CGHAFAHDA+<CHE<CEE<:?BGAG@FEGBFBDDHG@G@ABDGHHII=4.48=@GGECEE<;@?>@@CA>;@;CC@ACCCC@9
@1YC
CCCCGTCGTCTGCACGCAGCCCAAATCCCCATCCAGCACGCCAGTGTCCCCACTGCATCATGCATCTCCAAACTCAACTCATACACCGAAACCTGACCGGG
+
CCCFFFDDHFGHHIJJJJIJGIGIHIGIJJJJJJIJJJJDHIGGHIJIIJGEHFDFFFFFFEDEECEECCCDDDDDDDDCCCCCCDCDDDDDDDDDDDDDD
@1YD
AGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCAC
+
@CCFFFBFGHHHHJJJJI<FHGIHIIJIJHHGIJJIIEGIJJJJJJJIIIIJIIJIJIIJCIJIJHHGEFFFCEDEECDDDDCCCCDCC@CCCDCDEDDDD
@1YE
CTCAGTCTCTGAAAGATGAGATCGACGTGCTGAGACATTCTTCTGATAAAGTATCTAAACTAGAAGGTCAAGTAGAATCTTATAAAAAGAAGCTAGAAGAC
+
===;AAAABBB:=AAA++<=++<?+2?A15?ABB*0)0:===<A7=*=A?4=*9=>>ABBB=AAA4(7.=A>A7=>>;>>;;??@9>><(,;;=;=(9995
@1YF
CAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATAT
+
@C@DFDDAFHFHDFGHIHHE@HHIJGEGFHDGG9E;BGHHG;FGIGGGHDDGHIEG:CG;@FGGDEHHEFFFFF@CEE:;CBDCABCDDCDD>AACDDC
@1YG
CCTCAGTGAAAAAAATCAGTCTCAAGTAAAGGCCAACCAAGCCCTCGAGCAGTTATTCCCATGTCCTGTATAACCAATGGAAGTGGTGCAAACAGAAAACC
+
@@<BFDBDDDFDHDDEF@CCEHHGEH?EGHC@@GIGIGICFAGGECBHHBHI@DEHFEFECBB;CEBA;>>CDC>AAACCD>?:@CC?CCDDDDCCDDDA?
@1YH
CTACTCTTCATGGGCTATTCCACAAAGCCACAACTGGCTATTGTTACCCAGTGGTGTGAGGGCTCCAGCTTGTATCACCATCTCCATATCATTGAGACCA
+
@@<7D?DF?HFHHGGIGIEDHGEGH@BHGFHGCBGH<=DAF@?BGC>F@EH3BB0BF=GICA;DCEDEHA=C@BE;3;BCE9>AECCCCCDCDCC@<>??
@1YI
CTTGAGGGTCCTGCACCTCCATTTGTGACAGCATCTAATGTGAAGACCATTCTGCCCTCTAAGGCTGTTGGTGTCAGCCAGGAGGGTCCTCCAGGCCTTCC
+
??@DABDBHHDDDFH>GFEEEEHII?<<9???CFHIIBCDHGIBDAB???BFEBFDBBB=FHC@FCC=7==EAHHHEDC>??CCCB=CA>CA9>5??:@CA
@1YJ
CGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCCGCCCAGGATATGGACAGAGAAACAACAGTTAT
+
;;;?=<91=;1;8)2=)((.33()2;:;)6.>>?>:>16:<18)0).:=<16;=5-9;));)6=/(39''3;&&(((+(86:<<5(26(+5((+(2((+:/
@1YK
GAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGT
+
==>AAAAAB<+?CCBA@+?AB>>7AA>3?ABA?B<AA9AB>A5)=='5=;>ABA55((;=@(,.>=???;;>;9;?:((,:3;>>;38:8::=;?<(883
@1YL
CCTCCATCAGTGACCTGAAGGAGGTGCCGCGGAAAAACATCACCCTCATTCGGGGTCTGGGCCATGGCGCCTTTGGGGAGGTGTATGAAGGCCAGGTGTCC
+
@<=?ADDD?FFF>4EEFFF<33+)2AFF8FF0?FF>FE=F=@DEEDEEEEFABD83;@B??<98>,5<8;559AA9>9(55++>4>:A:>A@?2<?4:::3
@1YM
GACGGTTTCGCCGGCAGTCTCGATGATAGTATTTCTGCTGCAAGTACTTCTGATGTTCAAGATCG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJHJJJJJJJJJJIJJJIJJJJJJJJJJJJJJHHHHHH
@1YN
CCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGT
+
@@@DDD4DHHBFHEHBBHIG??CDFGCFHDGEGGGIIEHIIEHGGHECGGGGHHEHHEEC>CBBC@@ACCCBB;ACCCC?@B?=@CCCBBBC?CCCC??BC
@1YO
ATCAGAAGCCACAAGTGGGAATGAGGCCCTCCAACCCCCCCACACCATCCAGCACGCCAGTGTCCCCACTGCATCATGCATCTCCAAACTCAACTCATAC
+
CCCFFFFFHFHHHIHHIIJIJJIGIJJIIHJJFIJJJIIJGIJEHHHHFFFFFCE<>@DDACDDCDDDDBCDCDDDDCDCDC@CDCDDD@C:CDDDDDDD
@1YP
TTGGATTATAATCATGAGATTTTAGGACAGCAAATTAATGACTTTACCCTTCCTGATGTGAACCTTATTGGGGAGCATTCTGATGCAGCAGAGCTTGGA
+
7==A<4AA=,27@CABB7+A9A@>+<7AB<3=C;ABAA=?A<1=AA?<A>A>>AB>AB==A7A(7>)/>==='--:5.7);?@?@@5>9=55(;>?==?
@1YQ
CATAATTCTTGGGAAAATTCAGATGATAGCCGTAATAAATTGTCGAAAATACCTTCAACACCCAAATTAATACCAAAAGTTACCAAAACTGCAGACAAGC
+
;?@DDBDD?FFFBAGHEGEBEE@HHG9DBDHIIIIIICHCEG?FDFHGIIIIIEC;FHGIG7@C6@;>EF>EEEEEECC;>CCCCCB@@CCCCCCBBCBB
@1YR
GAAATCACTGTGCTAAAGGCGGCTTTGGCTGATGTTTTGAGGCGACTTGCAATCTCTGAAGATCATGTGGCCTCAGTGAAAAAATCAGTCTCAAGTAAAGG
+
@CCDDE8DHHHGBHIIIECBGGIHIDFHGIIDFHDHGGG?FGGI<EB?DECAAC@@DEDDCDDDACCACCABCBDC5>:>@@B<?A>C:@CCDCC@C:C>@
@1YS
TGACTGTTGGAGAAGAAAGTAAGCAAGAACAGTTGATTTTGGATCACTTACCATCTGTAACAAAGGAATCATCACTTAGAGCAACTCAACCAAGTGAAAAT
+
CCCFFFFFHHDHHJHHIIJCHHIIJJJJJJJJGJJJIJJJJIJJIJJJJJJJJJJJJIIJJJJJJJJJJJJJJIHHHHGHFFFFFEEEEEEDDDCCDEDDD
@1YT
AAAATTTCCAAGGACGTTTATGAGAACTTCCGTCAGTGGCAGCGTTACAAAGCCTTGGCCCGGAGGCACCTATCCCAGAGTCCTGACACAGAAGCTCTTTC
+
CCCFFFFFHHGHHIJJIJJJJJIIJJJJJJJJIJJJGIJJJIJJGIIJJJJJJJJJJJIJJHFFDDBDDDDDDDDDDDDDDDDDDDDCDDDDDDDDDDDDD
@1YU
TGGACAGCAGATACTTGTGCCCAGCAATCAGGTGGTCGTACAAACTGCATCAGGAGATATGCAAACATATCAGATCCGAACTACACCTTCAGCTACTTCTC
+
@CCFFFFFHHHHHJJJJIJJJJJJJJJJIIJJFHJGIIHIIJJJJJJIJJIJJJJJJJJJJJJJJIJHHHHHHFFFFFCDDDDDCDDDDDDDDDDDDDDDD
@1YV
GATAATCAGCGTCCACTGCTGAAGACAGACATGGAACGTCACATCAACGAGGAGGACACAGTGCCTCTTTCTCACTTTGATGAGAGCATGGCCTACATGCC
+
@@@FFFFFHHGHHIIIJJIJJJIJJJJJJJJJJJIJJJJIGHIGIGIGIIJJIJJIIGHHHHEFFFFFEEEEEEEDDDDDDDEDDDDD@CDDDACDDDDDC
@1YW
CAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATAT
+
@@?DBDDBACDDBCCCBG>CEAFHEGHGIIGEHIIHHIGD?FIEEAHFHDEBBHGCGG@FHGGAECHH@BD?7;@;>6>3;?B?;5>C::?C:@DCD@C
@1YX
GGAAAGGAAAGTGGAAAAAACCTGAGAACTTCCTGATCTCTCTCGCTGTGAGACATGTCTGAGACTCCTGCTCAGTGTAGCATTAAGCAGGAACGAATTTC
+
BCBFFFFFHHHFHIIJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJIJJJJJJJJJJJJJJIJHHHHHFFFFFFEEFEEEEDDDDDDDDDDDDDDDDDD
@1YY
CGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGC
+
@@@DFFFFGHHHGIIIJJJIJJJIJIGEIGIGIJIJJJJJIIIGBDFHGGIGGGIIGGGIJJJGEECHHFFFEB@CCD@CE@DDDDDACCBDDDBDB<@D
@1YZ
GAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGAT
+
BBCFFFFFHHFFFIJJIJIJJJJJJJJJJJJJJJIJJJJJJJIDHHIIJJJJIIJJHHFFDEEDDDDDDDDDDDEDDDDDDDDDDDDDDDDDDDDDDDDD
@1Z0
ATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCT
+
@@@DDDADAF<>FGGHBFIGGGIIIIIIGHIGCHGD9FHIGCEFCGCGICGGIABCG;FH@EIEEDEA@CCCBCCCAC?CBBBBBBCA@:@CCC:@CCCB?
@1Z1
GTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACT
+
CCCFFFFFHHHHHJJJJJJJJIIJJJJJIJJJJJJJJJJIJJJJJIJJJIJIIJJIJJJJJJJJJJHHHHHFFDCDDDDDDDDDDDDDDDDDDDDDDCCC
@1Z2
AGCAGCGATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGC
+
+==?2<002<77=+)2@<7?C7A;71?11*0??B>BA<=A(=B;A)8)=)..7...)==.65>37(..6.6;>==??=-59855(5(;5(228=7:;;==
@1Z3
CTATGTCACCTCCTGTTTGCGGAAGAAAAGGAAACCTCAAGCTGAGAAAGTTGATGTGATTGCCGGCTCCTCCAAGATGAAGGGCTTCTCGTCCTCAGAGT
+
@@@DFDFFHAHFFIGHGEI@GHFGG>BDCEHEEHII>?GDD@?FDBCFHG@FFEFIGICEIIGEAHEABAECCCDC;;@CCCCDB?B9>><8<@BDD?:A4
@1Z4
TGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTT
+
@@@DDDDBBFHGHGBEGHHIBF@GHBEB><EGFEAGAH9FG??DBDHH@G@BDDBCHIEACEHE;6CA??HHFB;);@BCEABBCBBB?5>ACDC@CCC>:
@1Z5
TGGAGTCATGCTTATATGGAGCAAAACTACTGTAGAGCCCACACCTGGGAAAGGACCTAAAGGGGTATATCAAATCAGGAAACAAATCAAAGCTCATGATG
+
1??DD;+A,?B44C+A<DADDEAAEDE9EEAA9C4*11:8C8?;)0BDDD??@@B(.)=@)=A(5'5)))).;73).>(6>;(-;;;>555:5(,,(5:(5
@1Z6
CAAGGACAGAGAGAAAAAAAAGAGGAATCTCATTCTAATGATCAAAGTCCACAAATTCGAGCATCACCTTCTCCCCAGCCCTCTTCACAACCTCTCCAAAT
+
CCCFFFDDHHHHHHHJJJJIJJHIJJJIJIIJJJJIIIIJIGIJJIG@FGIGIIJIHGHHHFFFDEEEDECDDDDDDBDDDDBDDCDDDDBDCCCDDDDCC
@1Z7
GAAATAGTTTATTTCATTGCATCAGTAGTAGTACTATTTAATTATGAGGAGAGAACTCAGCGACACTACCTGGGCCATACAGACTGTGTGAAATGCCTTGC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJIJJHIIJJJJJJJJJJJJJJJIJIJJJJJJJJJJJJJJJJJJJJHHHHFFFFEEEEEECDDDDEDDDDDDDDD
@1Z8
TGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGG
+
??;BB??DBDDDDIBE>C<CB:<+<CCFFB@EEE4??B?@0?D3?66@-;67@=ACD=?D@66@56;33>AA>>3>A:5:>A:>3+4+::(:>:>AA?9(+
@1Z9
GAGCCCCGGACCGAATCGGCTCTCTAGGCCGTGGAGCTTGCCGTCCCACCTCCGTCCAAATCGACCTTTCCTTTCTATCCCCAACCACCCCTCAACCCCTG
+
8=?=DB@AAFDFHI>DGGEAHIGEIIIIB>BFH<;@7;A=AHB59ABE?BB?BBBCB?>>>A?0&5;CCCCCC@A@(:AC@?982<<BBB><><@AB<5(2
@1ZA
AGCAGGAGTACCACGACCCAGTGTATGAACACAACACCATGGTTGGCAGTGCGGCCAGCCAAAGCTTTCCCCCTCCTCTGATGATTAAACAGGAACCC
+
@C@DFFFFBFFFHJJJGIIIIGIFGIHIJJIJJJ=HHIJJIJEHIJIJI@AHIJFFFFDDEEDDDDDD@CDDDDDDDCDDCDDDADEDDCDDDDDBBD
@1ZB
AGAAAAGGAAACCTCAAGCTGAGAAAGTTGATGTGATTGCCGGCTCCTCCAAGATGAAGGGCTTCTCGTCCTCAGAGTCGGAGAGCTCCAGTGAGTCCAGC
+
@@@DFFFFHHHDHHIJIHFGHIIIGIGHHHEGIFHIIJJJJJIIJJDIJAFGHCFGIJJIFHHHGEFFFFDDEEDDC;>@B=B?BDCCDDC@CCDDDDDDC
@1ZC
GCAGCCACATCCGACCGAGTCGTCCATGTACAAGTACCCTTCTGACATCTCCTACATGCCTTCCTACCATGCCCACCAGCAGAAGGTGAACTTTGTCCCTC
+
==<A<+2=CA+?AA<CA<)11?==5=AAB<<ABBAABBABBBBB9ABBBA>A;7AA>AA).7>@@?>@>6;;5;3;;;9:::;>;95;:=?????8;3:3;
@1ZD
GCTGAAGAAAACTACAGAGGAACTAAATGAAGCTTTGTCAGCAAAGGAAGAAATTGCTCAAAGATGCCATGAACTGGATATGCAGGTTGCAGCATTGCAGG
+
@@@FDBDBDHFFDGGII@EE>GGGGCBEHHBHCFHID?DG@DECCEFEH8DHGCBBCCBEIG<FAGECG@>=DC=CA>ACCFEFDB.(;(>ACB>AACA@B
@1ZE
CTACAAGCCAGAGTCGTCCCCTGGCTCAAGGCAGATCCAGCTGTGGCACTTTATCCTGGAGCTGCTGCGGAAGGAGGAGTACCAGGGCGTCATTGCCTGGC
+
=??DDD3:+ABD;2C<AEEIIIIIICDE>3BCD?DEIICDD*?/?DDBC;BC@CC>)8@AACC)3A378>8?8>(<?1<,:::;>?>85&0)2:>44>A><
@1ZF
TGGAGATGTTCTTACTGGAGACTCAGGTGGAGTCATGCTTATATGGAGCAAAACTACTGTAGAGCCCACACCTGGGAAAGGACCTAAAGGTGTATATCAA
+
CC@DDBDFHGHHGJIJGIGHGHGGIIJAEGCGFGGIIIIHIIJJIIHGIGGJHGGCDDHFGIIGGIIJIAEHEEHFBCBBEEEDCDDACD3:ACDCDCDC
@1ZG
CCTGGCTTACATGAACCACATCATGGTCTCTGTCTCCCCGCCTGAAGAGCACGCCATGCCCATTGGGAGAATAGCAGACTGTAGACTGCTTTGGGATTACG
+
CC@FFFFFGHHGHJIJGIIJJJGJJJEHGHIIGHGHJIJJJJIJIJGIIJGIJJJJJJGHHFHHGFEBFDEEEDACCCACDCDDDDDDDDDDDDDDCDDDD
@1ZH
GGTCAATGTGGAAACTGGGGAGGAGGAGAATTTTAGCTAGAGGGGGAGGGACGTGGGGGGAGGGGTAAAGAGCCGGGCGGTGGGGGGCCAGGACTTCA
+
1:+++2,,2,27++2+2<A)41)+))))1)1****009*07*)0'5'5'59(,9;=/'3)&&&&&&&++++(((&&&&)&&))05&0&02((+(+(+(
@1ZI
CGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCA
+
CCBFFFFFHHHHHJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJIJIJJJJJJJHHHHHFDDDDDDDDDDDDDDDDDEDDDDDDDDDDDDDDDDDDDC
@1ZJ
ATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCC
+
=1=1+2+@7=A@+7>AA@BB,+?AB7+<3<AB9AA=77?AB7?=)707*)09<7988==(5>>;5;A>))=>>>>>>@(6>>'3726(5983:==?<((88
@1ZK
TGGATCATTTGGAACAGTCTACAAGGGAAAGTGGCATGGTGATGTGGCAGTGAAAATGTTGAATGTGACAGCACCTACACCTCAGCAGTTACAAGCCTTC
+
@C@DFFFFDHGHHJIHIIIJIJJGIIJHGIJ?FHGIJJH?BB@FFGIJJIHAFHIGIIBFGGJBH@GHHIIIIGHHEFDFFFFECEDEDDDCDD>ABCDD
@1ZL
GAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGC
+
;?1AD;BBD??DDIEEA3CF<CECFE>+<?EE;B>9?C?B;?BBD>D>D?DBDBDE@EEE7@ACC:=2?AA<@6;@@A3>>D>AA;:(:<:>;5;5:>AAA
@1ZM
CTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJHHHHHFFDDDDDDEEEDDEDEDDDDDDDDDDDDD
@1ZN
AGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATG
+
CC@FFFFFHHHHHGHIJJJJIJJJJJJJJJJJJJIIJJJJIJJJJJJJJJJJJJJIJJIJJJGIJHHHHHFFFFFEEEEEEEDDDDDDDBBDDDDCEEED
@1ZO
TACCCTCCCACCAGCTATTTCTCTACACAGCCGACTAGTTATGATCAGAGCCGTTACTCTCAGCAGAACACCTATGGGCAACCCAGCAGCTTTGGAAAGCC
+
;13=?)6@()29322))2=)2)))))))2(.:-19:5..<)096:9193)3(5-;((.))).)6)(.3..(9((3(7;873(;',,227(+(+68((((+(
@1ZP
GCCCTCTCTCAGCCCCAGCAGAACAAACCAAAGAAAAAGGAGAAAGACAAGAAGGAAAAGAAAAAAGAAAAGCACAAAAGGAAAGAGGAAGTGGAAGAGA
+
@@@DFFFDDFFDDHIIIGIIIIIDBHE?CGHIIIDHIIHBGHEFHGIIGIGBGGHIIIIGFHHHDCCDDCCDBCCCDDDCBBCDDCCDD@B:@CCCCBD?
@1ZQ
TGAAAAGCCAAAATTTGTGCAGTGTTTAGCATTCTTGGGGAATGGAGATGTTCTTACTGGAGACTCAGGTGGAATCATGCATATATGGAGCAAAACTACTG
+
11+=4ADD>DDCDC:BE<C@ABE9AAE42<2A@DECDED@DADDEE@?3?*/?D8BCBA:BB3(8.==9=@;=).=;A37))7.;6;@@9;;;>((::>>>
@1ZR
CATCACCCTCATTCGGGGTCTGGGCCATGGCGCCTTTGGGGAGGTGTATGAAGGCCAGGTGTCCGGAATGCCCAACGACCCAAGCCCCCTGCAAGTGGCTG
+
CCCFFFFFHHHHHJJJJJHIIJIJIJJJJJJIJJJJJJJJJGHJCEDHHHHHHFFFFDD@CACDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDACDDDD
@1ZS
GAAAACTCAAATAAAGAAGAAATACAGGAAAAGGAGACAATCATTGAAGAATTAAACACAAAAATAATAGAAGAAGAAAAGAAAACTCTTGAGCTAAAGG
+
CCCFFFFFHHHHHJJJJIJJJJJJJJJJIJJJJJIIJJJJJJJJJJIJJIJJJJJJJJJJJJIJJJJJJJJHGHHHFFFFFDEEEEDDDDDDDDDDDDDD
@1ZT
GCTGTGAAGACGCTGCCTGAAGTGTGCTCTGAACAGGACGAACTGGATTTCCTCATGGAAGCCCTGATCATCAGCAAATTCAACCACCAGAACATTGTTCG
+
???D;D4A?FFFFBFEFF?GGEHHABFEBDEEEDFEFIFIFFIIIFFFFFFIIFFFD;@C@CEEFCBD@>B@BCCCCBABBBA>?<??<<2>?BBBBDBB@
@1ZU
CTCCGCTATTACTATGAGAAAGGAATTATGCAAAAGGGGGCTGGAGAGAGATATGTCTACAAGTTTGTGTGTGATCCAGAAGCCCTTTTCTCCATGGCCTT
+
+:?DDDDDHHH?FGGHGIGCEGIGGDGE>GBHIIIII)?DFHIG@F=CC==A@>?CC;.7@CB;@CC(>.=,=CDACCA:>CAB<?CCA:@CCC@CC@CCC
@1ZV
CTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJIJJJJJJJJIJJJJJJJJJJIJJJIJJJJJJGIJGIIIGIJHHHHHFFDDDDDDDDEDDEDEDDDDDDDDCDDDA
@1ZW
CTCCAAATACACAGACAAACTCCAGAAAGCAAGAATGCTACTCCCACCAAAAGCATAAAACGACCATCACCAGCTGAAAAGTCACATAATTCTTGGGAAA
+
?@?AA?DAFHDD?CFHEICHFHIDGIICGEGBCEE<CED@BBDHEIDHIGIBHGI>FHEAGIBGAE@>CE@>?A3@5@A@>-;AC>;@>>BA>@:ABBCA
@1ZX
TTTTATGGTGGGACGAGGATACCTGTCTCCAGATCTCAGTAAGGTACGGAGTAACTGTCCAAAAGCCATGAAGAGATTAATGGCAGAGTGCCTCAAAA
+
@@@FFFFFCFD>DGACAHEAFGIICGDGHIIIIICHIIIGHIGGDGGHIHA@FE=EG@GHHHGHEEFFEECAC>@AACCCCCCBCBCB>CCCACCCCC
@1ZY
ACTGGATCCTATAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGT
+
<@@DFDDFHBDAF@FHG@GIGIGGFFABHEHGHGHCHGG@DFFG@H@GF?DBBFGIEA;BEEGEE?AHECBEFF9>BBB??<?BBBBBB@CCC@ACAB390
@1ZZ
CTTCAGTATGCACAGACCTCTGATGGACAGCAGATACTTGTGCCCAGCAATCAGGTGGTCGTACAAACTGCATCAGGAGATATGCAAACATATCAGATCCG
+
C@CFFDDEBDHHHJGBGGCHJGGGHIGEHA=FHIGGDGHDFIGGBFBFHIGFHGH8DD;C@FGIGC@EC>>E>>@>DC?;@>C;ADCD;?;@CCCDDC:CB
@200
GGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTAC
+
B@CFFFFFGHHHGIJJJIJJJJIIJIIIJJJJJJJJJJJJJJJIJJJJJIIJIJJHHHHHFFFFDDABCDDDCDDDDCCDDDDDDDDEDDDDDDDDCDDDD
@201
CTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTAT
+
CC@FFFFFGHHHHJJJJJJJJJJJIJJEGGJJJGIIJJJIJAGCIIIIJIGE=AEHHFFFFDFEEDDDDDDDDDDDDDEDDDDABDADDDDDDDDDDDDDD
@202
TACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTT
+
@@CFDBDDHFHHGIIJEFHHIIIJIJJJIIIJJIJIJJGIJJIFHGIHIJJIIII<G@GIGIDIIHHHAHEFFFFEEDEEECDDC@C=;5ABDDDDDC@C
@203
AGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGAC
+
C@CFFFFFHGGHHIIJJIIIJJJJIJJIIIJGIGGGHGJIJJJJJJIJJJJJHHGFFFFFEBCCEEEDDCDDDDDBBDDDDDDCCDDDDCDDDCDDDCDB
@204
GAAATAGTTTATTTCATTGCATCAGTAGTAGTACTATTTAATTATGAGGAGAGAACTCAGCGACACTACCTGGGCCATACAGACTGTGTGAAATGCCTTGC
+
CCCFFFFEHHHHHJIIIIHIIJIIHHJIJIJJIJJIJJJJJJJGGGDHIGGGHIGBHHIFGHJJJJGIIGHJHHHHFFEFDDEEEEDC>BDEDCCCDCDCD
@205
GTTGTTGAAAAGGATACAACAGAACTCATGGAAAAACTTGAGGTAACCAAGCGAGAGAAATTAGAGCTGTCACAGAGACTGTCTGATCTTTCTGAACAATT
+
CCCFFFFFHHHHGJIIJJJJJJJJJIJJJJJIJJJJJJJJJIJGHIIJJJJIIHJIJJJJJJJJFGHHHEFFFFFFEEEEEDDDDDDDEDDDDDDDDDDDD
@206
CGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCC
+
CC@FFFFFHGHGHIJJJIIHIJJJIJJJJJJJJJJIIJJJJJJJJJJJHHHHHHFFDFEFEEEBDDDDDCDDDDDDDDDDDDDDDDDDDEDDDDDDDDDD
@207
AGAAAAAGGAAGCAGAAGAAGAGGATGAGGAACTCTCCAACTTTGCTTACCTCTTGGCCTCTAAACTTAGCCTCTCACCAAGGGAGCATCCCCTCAGTCCT
+
=8?=;BD81<C:<E@2+<FFA+88FD>E@3:?B9CD3?DED;B?BDEIC?;<B<=C:;@;6ACEE>ACCDCCDD3;37;@@65>?;6=>:>?<?=?A+4>>
@208
CCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATG
+
11=7<<AACBC4<2A4<?C37ACB+<++:A>*1*:=?BABB3*00=0*9A*>=5A()))'5AAA4(;5).)(((..;@;'92=:25=98;95(883(8(8=
@209
CGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCT
+
?@?DDDDBHFB?:<EFEEHAEFHDGGDFHGG:9?EDAFD?DG9BGC@G@GG<?;F=FGEGIIA=6@;AEHHHE<BECCBB??@C?C>CCCCCCCCBB?BBA
@20A
CTTTGCCTAGAAGGGGAACCAGGAATGCCATAGTTCCGAGAGAAACTTCTGTTAGTAAAACACACAGGTCAGCAGACAGGGCCAAAGGAAAGGAGAAAA
+
?@<DB?=DDFBF?FEHEABD>BCFGBCGFGIGEGBDHE@@FACD=.=B9CF=F;F8=CEADD@CBED?7;@C@>AEAA=B@8?1<99<(>38?8A88>C
@20B
CCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGG
+
@@@DD;DDDAHBDFGIEBGG;A<AFHIGHICGA?EFHFIHB<B=??BFCGDGEBHG>CAEBG;EEFEEDDDEDDDEECB>>B?B??@@BB<@<@CCCCDCB
@20C
TGAAGTTGTTTTGGCTGTGGAGTTTCACCCAACAGATGCAAATACCATAATTACATGCGGTAAATCTCATATTTTCTTCTGGACCTGGAGCGGCAATTCAC
+
@;=DDBD;=3:AF@?AE<?:<<22<<2<FD??GGEB?F<*::F?9D<98?DF<88=8B@@-;@CCEFCEEEEEEBBDDDB>>3;@CBB@=328809B>>B:
@20D
TCTGTCTTTGATGAAGACAAAACTTTTGTAGCAGAAACATTGGAAATGGGTGAGGTTGTTGAAAAGGATACAACAGAACTCATGGAAAAACTTGAGGTAAC
+
?@@DADDEDAH>BGIEHIIIIIIIEHIGAHAHHEHGGBHHGAGHIGGAFB9DA??DFGIGGCEGGHD@@HGHGEE;BEFEFDCC>CCE?BBCC@C:<>:>@
@20E
ATTTATATGAGGCAAGAAGGCTTCCTGGCTCATCCCAGCAGAACAGAAGGCTGTATGTTTGAAAAGGGCCCCAGGCAGTTTTATGATGACACCTGTGTTGT
+
?@=DDA?DFHBHF?EHIEH;::<:CAC;G?:?CHIID9???9B@D?FG??D8=.8B<88CH@@CEHIIHC=DE?CA?==;>@CCC:;ACACA??>::C9?3
@20F
CCAGAGATGAAGCAAACAACAGTGGAGTCATAAATGAAAGCTTTGAAGGTGAAGATGGCGATGTGATTTGTTTGAATTCAGATGACATTATGCCAGTTGCT
+
CCCFFFFFHHHHHJJJJJJJJJHJJIIIJJJJJJJJJJJJJIJJJIIIJDGIJJIIIJIIHIJHIIIJJHHHHHHFFFFFFDDEEEDEDDEDDDDDDDDDD
@20G
CACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACC
+
@C@FFFFFHHHHHJJJJJJIIIFGJGIIJIIJJJJJJJJIIIGIGHGIHIEHJFIIGHGHEGIFGIHHFHHFEDDDDDDDBACBCEDEEDEE>@DDDDDDB
@20H
GAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCG
+
@@@D@BDDDAHAFGDG<<D=;:CAB@H@F8A;;@FGA3?DH)B;FGGGGE*?BBBHHC8C@@GE==DHFFHH>BDBC>;;;9@>A;3;;@CCCC9:9?@B
@20I
CTAACTCTCAAAAGGAAAAACTCAAGGAAGAACTAGGACTAATTTTAGAAGAAAAGTGTGCTCTACAGAGACAGCTTGAAGACCTTGTTGAAGAATTGAGC
+
@@@BBDDDHHGFGEHGIIEE@GHHJIGIGIGHGFDHGHIIIGHGHHIIEGIGHGH@GA=CFHGIGHIIGADGHHEHHFFFCDCEEECEDBCA>>;CC::A@
@20J
ATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJIIJJJJJJJJJJJJJJIJJJJJJJJJJJJJJIJJJIJJJJJHHHHFDDDDDDDEDDDDDDDDDDDDDDDDDDDDD
@20K
AGCAAAAGCCCACTGACGCTCCACCGAAAGATGATTTTTGGATACCAGAAACAAGTTTCATACTTACTATTATAGTTGGAATATTTCTGGTTGTTACAATC
+
CCCFFFFFHHHGHIJJJEHAFGIJEGFIIIJJJIJJIJJIJJJIJJIGIJIJIJJHIHHHHHHHFFFFFFFEDEDEFEDDDDDEFEDDDDDDDDDDDDDDD
@20L
GGTCTCCTGAGCTACATCAATGAGCTGTGTTCTCAGAAGGTCTTTGTCTCCAAGGTGGAGGCTGTCATTCACCCTCAATTTCTGGCAGATCTGCTGTCCCC
+
@@@BDFFFDHHGFHIEHCGHBIHDHGGECHGGICIDFCFG?:CGGHGGGGIIGIIAFGBDF@CHH@DGHE=CHG=EHEEDEECEFECD?@CCCC@>>@CCD
@20M
CGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCA
+
@@?DDDDDDHGHGI@B?FHEGHECHD@GGEGIEGGCHIFHIIIEFDEHHGGIE;CHCCE?9=A83;?B=@ABDDDCCCDCCDDDD<@BDD8?@BDBDDC
@20N
GTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCC
+
===AAAA>17?)?A=)<?ACBAB=?A<A?A:<<A<4=A7AAAA<A=;===AAABA@@)7>>>=@@???;?===69<<8;<<99;:8;?=?=?;??9;;;
@20O
GAATGGGGTTGTGATGGCCCAGGTTCTTCAAAAGATAGATCCTGCATATTTTGATGAAAATTGGCTAAACAGAATCAAAACTGAAGTAGGAGATAATTGG
+
BBCFFFFFHHHHHJJJJIJJJJJGHJJJJJJJJJJJJJJJJJJJJJJJJJIJJIJJJJJJJJJJJIJJHHHHHFFFFFFEEEEEEDCDDDCDDDDDDEDD
@20P
CAGCTGCCCTAGAAAAGAGAAACTATTGCAGCTTGCCAGGACCTTTGAGGGCCAACAGCCCACCCTTGAGGTCCAAAGAAAATCAAGAACAGAGCTGTGA
+
;;?DD?DD?D?CFEH@?1AG@@GHDBBA<ACGGGHDDBCG8DHFAG<969D0;6=@CC;EI=55:6?DDEC636AA;;;5?C>55>C599><:9>:9A3(
@20Q
CTGAGACTCCTGCTCAGTGTAGCATTAAGCAGGAACGAATTTCATATACACCTCCAGAGAGCCCAGTGCCGAGTTACGCTTCCTCGACGCCACTTCATGTT
+
@@?DDDDAHF>FHBHGIGIAEHHEEHGGIIEGHEHEDGIIEBBGGGGGIHGEAFHIGEHCGGDFDG;@EHH<BBACCAB@BBCC>?BB@<>BBCCCCECAC
@20R
GGGGCGTTCGCAAGTGCAAGCCCCAGATGAATTACGACAAGCTGAGCCGGGCCCTGCGCTATTACTATAACAAGCGCATTCTGCACAAGACCAAGGGGAA
+
@C@FFFFFHFHHHIFHIIGJIIJJJGIIJGJIGG@HGIGIFEAECDDDFBBBBDDDDDBDD;CDDDEEDDCCC?AB@DDDDDCCDCDDDDDDDDDDDD@D
@20S
CGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGG
+
BCCADFFFHGHHHJJJJIJIJJJEGEHIJJJJIJJJJIIJIJJJIJHHGHJIIJJJIIHFEFEDD@DBDDDDCDDDAACDDC<ABDCBDDBDDD?CDDEDD
@20T
CTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACT
+
@CCFFFFFGHGHHJJJJJIGGJDHJIIIJJJIJIJIJJJJJJJJJJIIJIGFJJJJJJIIHHHHHHFFFFFFDDDDDDDDDDDDDDDCCDDDDDDDDDDDC
@20U
TCTTACTGGAGACTCAGGTGGAGTCATGCTTATATGGAGCAAAACTACTGTAGAGCCCACACCTGGGAAAGGACCTAAAGGTGTATATCAAATCAGCAAAC
+
CCCFFFFFHHHHHJJJJJHIJJJHHIJJJJJJJJJJJJJIJJJJJJIIJJJJJJJJJJJJIJJJJJJJJHHHHFFFFEEEE;CCCDDCDEDDDDDDDDDDD
@20V
CCATCCAGCACGCCAGTGTCCCCACTGCATCATGCATCTCCAAACTCAACTCATACACCGAAACCTGACCGGGCCTTCCCAGCTCACCTCCCTCCATCGC
+
CCCFFEFFHGHFFIIJIIHJJIIIIIJIJGIEIHJJJJIIIJIGIJJGGJIJGGHIJIJIIIHHHFFDDFCDBBDDDDDDD@B3>CDDCBDDC?@CCDBD
@20W
GATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCC
+
:;84AA????D4<C:,<:?BF9FFG@3<<?*C:9*)1)))0?)?FDABB=F))=C@;@9@D==.7?=?;BB7??;;3;@>?A5(5:A>@@253(21<<<@B
@20X
CTGGAGACTCAGGTGGAGTCATGCTTATATGGAGCAAAACTACTGTAGAGCCCACACCTGGGAAAGGACCTAAAGGTGTATATCAAATCAGCAAACAAATC
+
CCCFFFFFHHHHHGIJJJHIJJJIIJJJJJJJIIJJJJJJJJJJJGIHIJJJJJJJJJIJJJIJJIJHHHHHFFFF;AACEEEEEDDDDDDDDDDDDDDDD
@20Y
CAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCC
+
@@<DD4BDFDB,2?CGG>BFG9AEEEA9FBA9FEFHC;GH@@FH6D>F?<FGC@ECBGHEGD@2CA=C>))??@DCCC=?;;?CCCC?>,(555>>>:>@
@20Z
CAAAAGGAGCAGAAATAAAGACAACAAATGAAGTTGTTTTGGCTGTGGAGTTTCACCCAACAGATGCAAATACCATAATTACATGCGGTAAATCTCATATT
+
@CCFFDFFGHHHHJJJJJJIJJIJJJJJJJJJJIIJIJJJIIJJJIIIIHGHIJIJJJJJJJIIFFFHHHEFFFFFFEDEEEEECCDD=BDDDDDDDDCDE
@210
CTTTCGCTATCGATCTCCTCATTCAGGTGATGTGCTCTATGAACTCCTTCAGCATATTCTGAAGCAGAGGAAACCTCGGATTCTTTTTTCACCATTCTTCC
+
@@?DBBDDFADHFFD;ECEDFHBHIHDEH9:::CBDGIIGGGIHEEHCBFGCB?BFHBHCHGCHIIIGGEDDAEC>ABB>=AC;ACCC@C@CCCAAC;>@C
@211
GGGAGACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTT
+
@@@DDDFFHHHH@GIIGGIIJIIIGHAHG@FHIICGGIIJIHDHCBBEFFEDDC@BCDDDDDDDCDCDCDCC?<@CDDCDC<B>>B@BDDB1<CDD4>ADC
@212
CAGTGATCTGTGGGCAGAAGGTTGCTTCCCATTGCTAGAAAGTGGTGATTCCACACTGGGGTCTTCCAAAGAAACCCTTCCACCCACATGCCAAGGCAATC
+
?;;4:A;BDFHHHIIGGB>GGAEFDFEGHIA@EB<C>@DGGI9DD9?F4?FFGGHB;3BCF5;@@@EH@D;AAADEB@CCCCCCB;@?:,:@@@?@B?<AC
@213
TGTAGCATTAAGCAGGAACGAATTTCATATACACCTCCAGAGAGCCCAGTGCCGAGTTACGCTTCCTCGACGCCACTTCATGTTCCAGTGCCTCGAGCGCT
+
@@@FFEDDHHACFGGIHIJIDCHIIJJJIIIFIIIEDF@FD=;?BGHGIDHGEHEIGGIIIBHHFFDF?CCBDDBDCCCCDDCDCDDCCCCCCCBBDDBB@
@214
CCACAAGTGGGAATGAGGCCCTCCAACCCCCCCACACCATCCAGCACGCCAGTGTCCCCACTGCATCATGCATCTCCAAACTCAACTCATACACCGAAACC
+
CCCFFFFDFHHGHJJIIJIJIIJJJIIGIJJIJJIJJJJIJJJHHGG=BEDDCCADDDDDDBDDDDCDCDADEDDDDDDDDDDDDDDDDCDDDDDD<>DDB
@215
TATTATTGTATTTATTTCCAGGCTTAATCATAACATTGCTTATTGCTCGTAGCTTTGTAGCATTCTTACCCAGGAGTTTTGTGGTTGACCAACCACACAA
+
C@CFFFFFHHHHHJJJJIIJIJJJJIJJIJIJIIJIIJJGGIGIJIJIIJJJIIJJFGIIIJJJJJJJIJJJJJJIJEHGCHEDFFDEDEEDDDDDDDDD
@216
GCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGT
+
CCCFFFFFHHHGHJJJJJJJJIJJJIJJJJJIJJJIJJIJIJJJJJJIIJJJJJJJIJJGJJJIJJJHGHFFDDDDDDDDDDDDDDDDDDDDDDDDEDDDC
@217
CAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGT
+
@C@BDDEFDDFHHEHIGIE@EHHGFHIIGIIDHIDIIIIIGICHGIGIIIGGIIGGEHFHHFFBDCE?BDDDCD:ADDDDDDD@CACDCDBDCCACCDCDB
@218
GGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJGIJJJJJJJJJJHHFFFDDDDDDDDDDDDDDDDEDDDDDDDDDDDDDDDDDDEDDD
@219
CAAGACACGGGCCCCCCGCCGGCGTCAGCGTAAAGCCCAGAGACCTCCTGCTCCTGAGGCACCCAAGGAGATCCCACCAGAAGCTGTGAAGGAGTATGTT
+
=:8+4=ADCFFFFF:FB<:FA0A<4=B<;=,((5@@B@B????9?8>?9@>99A33@@B??2<?8+28<?1?@@(42022239>>@4?>:@>(+++(::A
@21A
CTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJHIJIJJJJJJJJHJJJHHHHHHFFFFFEDEEDDDDDDDDDDDDDCCDDDDDDDDDD
@21B
CACCATTGAACTGTTGCACCGCTCCAGGTCACCTATCACGACAAATCACCGGCCTTCTCCTGACCCCGAGCAGCGGCCCCTCCGGTCCCCCCTGGACAAC
+
CCCFFFDDHHHFGGIJIIIIIJIJJJIJBFGIIJJJIJJIJJJIIIIGAFEGHHGGFFFFFFFEEEDDB?BBDBD<BDDDDDDDDBBDDDDD>BABBCD?
@21C
CCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGC
+
BCCDFFFFHFHGHIJIJJJIIJJHHGIIGIJJFGHGJJJJJJIJJJIJJJIIJIJGDHIGIIJJHHHHHHFFFFDDDDDBDDDDDDDDDDCDDCCDDBDBB
@21D
CAGAGACGCGTCTGTGGTTCTTTTGGACTTGCCATAGATGTAACCTAAAAAGTATTTGCATATTTAAGTCAGCTTAGGGGAACTTTTTTTTTCATTTAAAT
+
1:1442B;C)))<A++9):??99?:)1****0009**0****0*0888/B)'))/))...@.).77).==.77))).(6',955;5((259<C<443(:(4
@21E
GGAACACTTTTTCATTTGCTGAAAAAAACTTTGAAGTTAACTATCAAGAGTTACAAGAGGAGTATGCTTGCCTTCTCAAAGTAAAAGATGATTTAGAAGAC
+
CCBFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJFHJIJJJHIJEHCHGIIHHGGHFFFFFFEEECEEEDC@CDCFFEDDDDDDD
@21F
GACATTCTTCTGATAAAGTATCTAAACTAGAAGGTCAAGTAGAATCTTATAAAAAGAAGCTAGAAGACCTTGGTGATTTAAGGCGGCAGGTTAAACTCTT
+
CCCFFDFFHHHHHJJJIIFJIIJJIJJJJJGIIJAHHIJHHGJJJJIJJJIIJJJIJJJIGIIJJIJJIIJJIFHGIIJJGHHHFDDDDDDDDDDDDDDD
@21G
CACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGC
+
@?@DDDDDAFHHDGBGIBG@B@EGBGHGEFGIIGGEHGG@DDD@FHBGHDHIGAGFHGHE@=DC==>EEHDFCBBC>AA;@CBCBCDDA@@??CC@328
@21H
ATACACCGAAACCTGACCGGGCCTTCCCAGCTCACCTCCCTCCATCGCAGTCCATACCAGATAGCAGCTACCCCATGGACCACAGATTTCGCCGCCAGCTT
+
CCCFFFFFHHHHGIIIJJJIJIJIJIIGIIJJJJJJJJIJJJJJIIIHHHFFFDDEEEEC@CDCDDCACDDDDDBDDDDCD?ABACCCDDCDDDBDBDDDD
@21I
TGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGG
+
@@@DDDDDD?CFFHGID?EHCDHICAEEDHGEH@DBHFCBHAAGCEBB@AEDHI@EH6?BE;=ACC;=;C;5;>CCCC???::@@>@CC@DCCCCCCBC88
@21J
TATGTCTACAAGTTTGTGTGTGATCCAGAAGCCCTTTTCTCCATGGCCTTTCCAGATAATCAGCGTCCACTGCTGAAGACAGACATGGAACGTCACATCA
+
@@@DD?BD?FDHHGIGBBCGEBHHIGEGHIGGDHIIGGFHIGID<?;BDFIIGHB?<DGG=CGIIFHIGIGIFHHEEDE@CECCCCCCCCCBBBBBCCCC
@21K
AAGGAAACCTCAAGCTGAGAAAGTTGATGTGATTGCCGGCTCCTCCAAGATGAAGGGCTTCTCGTCCTCAGAGTCGGAGAGCTCCAGTGAGTCCAGCTCCT
+
CCCFFFFDHFBFHIIIICGBHIECHIIIIHEFIICHFHIIIGGIGGIGGGIIIIIGIIIIHGCEHHFFDFEEDECD;>B=B@CDDDD@CCDDDDDDCDCCC
@21L
CCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTAT
+
CCCFFFFFHHHHHJJJJJJJJIJIJJIJJJJIJIFHHIJJIIIIHJJJJJJHHHFFFFFEEEEEDDDEDDDDDDDDDDDDDDDDDCEDDDDDDDDDDDDDC
@21M
CTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGC
+
CCCFFFEFHHHHHJIIJJJJJJJJJJIJJJGIJJIJJJJJJJJGIJJJJJJJJJJIJJJJIIHHHGHFEFFEEDDCEDDDDCDDDDEDEDDDCDDDDDDC
@21N
CGAGGAGGACACAGTGCCTCTTTCTCACTTTGATGAGAGCATGGCCTACATGCCGGAAGGGGGCTGCTGCAACCCCCACCCCTACAACGAAGGCTACGTGT
+
CCCFFFFFHHGHHJJJJJJJIIJJJJJJJIJJGIJGFAGGIIIIIJIIJJJJIJGJJJJJHHFDBDDDDDDDDDDDDBDDDDDDDDDDDDDDDDDDDDAC?
@21O
TGCCGAGTTACGCTTCCTCGACGCCACTTCATGTTCCAGTGCCTCGAGCGCTCAGGATGGAGGAAGACTCGATCCGCCTGCCTGCGCACCTGCGCTTGC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJIIJJJJJIJJHHFFFEEEEEDCDDDDCBCDDDDDDDDDDDDDDDCB>BBDDCDDDDDDDD
@21P
CTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJIJJIJJJJJIJJFHIJJJJJIJJJJJJJJJIJHHHFDFFEEDDEDDDDDEEDDDDDDDDDDDDDDDDDDDD
@21Q
ACAGAATCAAAACTGAAGTAGGAGATAATTGGAGGCTAAAGATAAGCAATTTAAAGAAAATTTTAAAAGGAATCTTGGATTATAATCATGAGATTTTAGG
+
CCCFFFFFHHHHHJJJJJJJJJHJHIJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJIIJJIJIGJJJHHHHHFFFFFFFFECEEEEDDDDEDD
@21R
GCTCCTCGGACAGTGACAGTTCGACTGATGACTCTGAGGAGGAGCGAGCCCAGCGGCTGGCTGAGCTCCAGGAGCAGCTCAAAGCCGTGCACGAGCAGCTT
+
@C@DFFFFFDHHHGHIJJJEHIGHHGIJGHGIIIIIHIGJJGCGHEIGHEHHHHDDDDDD?CB@D@>CDCDC?<<?AB?C@CDC?B@-9>AC?9BBBDDCD
@21S
ACTGGATCCTACAGCCAAGCCCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGT
+
CCCFFDDEHHHGHEIGIGEGFHIEHICCF>CEDFA@HIEGGGHAHICG>DGCAF@BBHHHHDEDE7@DEDCE<@<;:2<ABDAABBBBB4:4@CCC?B99@
@21T
CATCTCCTGTGACTCTCACCTCTCAGACAACTAAGACAGAGGACCCCCAATTGAAAAGAGAAATAAGGTTAATGAAAAACAGAGAAGCTGCTCGAGAATGT
+
CCCFFFFFHHHHHJJJJJIIJIJJJJIJJJJJJJJJIJIIJJJJJJJJJJJJJIJJJJGHIJIIJIHHHHGFFFEFFFEDDECDDDDDCDDDDDBDADDDC
@21U
GCTCTATGAACTCCTTCAGCATATTCTGAAGCAGAGGAAACCTCGGATTCTTTTTTTCACCATTCTTCCACCCTGGAAACTCTATACACACACAGCCGG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJIJJJJJJJIJJJJJIIJIJJIIJJJJIJHIJJHHHHHHHFFFFFDEDEDDDDDDDDFDDDDDDDDBDDDD
@21V
CAAGAAGGAAAAGAAAAAAGAAAAGCACAAAAGGAAAGAGGAAGTGGAAGAGAATAAAAAAAGCAAAGCCAAGGAACCTCCTCCTAAAAAGACGAAGAAA
+
@C@FFFFFHHHGHIJJJJJJJJJJJJJJJJJJIIIIJJGJJJJJFFGIGJIIGIHJJJHHFDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDD
@21W
CCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTTATGGG
+
@C@FFDFFHG?ADIJIIIIHGHIGIJJJJJJJJJIIJJIFIIJIEGIIJ>HHIIIIIJHGIHGHHHHDFDDDDDDBDDDDDD5@CDDDDDD9<9?CDDCDD
@21X
AATCAACACCGCTTTGCCGATAGAATATGGTCCACTTGTGGAAGAGGAAGAGAAAGTGCCTGTGAGGCCCAAGGACCCTGAGGGGGTTCCTCCTCTCCTGG
+
CCCFFFFFHHHHHJJJJJJIJJJIJIJIJIIJJJJJJJFHIIJIIIJIJJJJJJJJGIHHHHEHFFFFDDDDDBBDDDDDDDDDDD>BBDDDDDDDDDDDD
@21Y
ACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGT
+
CCCFFFFFHHHHHJJJJJJJJJJJIJHIJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJIIHHHHHFFFFFFEDDDDDDDDDDDDDDDCDDDDEDDD>@>
@21Z
CCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATG
+
CCCFFFFFHHHHHJJJJJIJJJJJJJJJJJJHIJJIIIJJJJIJJJJJIJJIJJJJJJJJJJIHHGFFFFFEEEEEEEDDDDDDDBBDDDDDDDCDDDDED
@220
GCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTAT
+
CCCFFFFFHHHHGIIJJIJHIIIJJJIJFHIIIJJJJIJCHHIIJJJIIJHIJJJJGJJJJJIJJIIIHHGGHEFFFFFEDEEEDDDDDDDDDDDDDDDDD
@221
GATGGACAGCAGATACTTGTGCCCAGCAATCAGGTGGTCGTACAAACTGCATCAGGAGATATGCAAACATATCAGATCCGAACTACACCTTCAGCTACTTC
+
B@CFFFFFHHHGHJJJJJJJEGIIJJJJJJJJJICGIHIJHIJJJJJJJJJJJJJJJIJGIJJJJJJHHHHHFFFFFFEDDDDDDDDDDDDDDDDDDDDDC
@222
CTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGC
+
@@@FFFFFFHHHHIIGGIIIIJIJGGGHHIIJIJJJIJJJIEGGIIHIHJJIJJIJIJIIJGHIJHHHGFFFCDFEEEECDEDDDDDDDDDDDDBD@CCD
@223
CAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGG
+
B@@BFFFFHGHFHIIIIIIJIHIJGIGGIJIIIGJHJIIIGIJJJIIEGGHCGIJJGGCGGIJIIAHGIECHEFBEFCECDEECCCCCACCCDDDDD?CD@
@224
CGGCACTCCGTGGATTTCAAACAGTCCAGGCTCTCCGAGGACGGGCTGCATAGGGAAGGGAAGCCCATCAACCTCTCTCATCGGGAAGACCTGGCTTACAT
+
CCCFFFFFHHHHHJJJJJJJJJJJIJJIJJJJJJJJJJIJJJJIJJJHHHHFFFFFEDDDDDDDDDDDDDDDDDDDDDDDEDDDDDDDDDDDDDDDDDDDE
@225
GGAATCATCACTTAGAGCAACTCAACCAAGTGAAAATGATAAACTTCAGAAAGAACTCAATGTACTTAAATCAGAACAGAATGATTTAAGGCTACAGATGG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJHIJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJGJHHHHHHFFFFFFFEEEEEDDDDD
@226
CGACCATCACCAGCTGAAAAGTCACATAATTCTTGGGAAAATTCAGATGATAGCCGTAATAAATTGTCGAAAATACCTTCAACACCCAAATTAATACCAA
+
CCCFFFFFHHHHHIJJJIJJJHHIJJJJJJJJJJJJJJJJJJJJJJIJJJJJIJJJIIJJIJJJJFDHIJHHFFFFFFEEEEEEDDDDDDDDDDEECDDD
@227
GGAAAACACGACATGTGAATATCCTACTCCTCATGGGCTATTCCACAAAGCCACAACTGGCTATTGTTACCCAGTGGTGTGAGGGCTCCAGCTTGTATCAC
+
CCCFDFFFHHHHAGIGHIJIIJJJJIIJJIIIGHIIIJIJJJJJJIJJJHIJJJJJJFJIIFGHHHHHHGHFDD@@C6??ADDD?BBDBCDDDCCBCCDCD
@228
AGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACT
+
CC@FFFFFHHHFGIJJJJJIJJIJJJIJIGGJJIJJIIJJJGIJJIGIJJJJGIJJIIGHIIHHHHHEDDFFFFEEEDCDDDDDDDDCDDDDDDDDDDCDD
@229
ATAAAACAGTTAATGGGGACAGTCGAAGAACTTCAGAAGAGAAATCATAAAGACAGCCAGTTCGAAACTGATATAGTACTACGAATGGAACAAGAAACAC
+
?@@DDD?ABCFDDHGGDF;@AEAEGIIEHGEEB<FCBB?FFIGDBGICFGDBBEBCFACAHHCDGCEA?=;BD@@@;@>;>;?BB=C@@A:<CCCCC>A?
@22A
GTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTAC
+
???BDDDD:A,<2<3:EE9;F<AA<;FF78C<D00:BD3D@8B*?8<C).@;/8@A77;7@)7??ADD@??@@AA:;;;????=5,5((55<???A34:>>
@22B
AGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACT
+
CCCFFFFFHHHHHJJIJJJJJJJJJJJJJJIJJJJIJJJIHHIJJJJJJFHHIJJJJHIJIHHHHHHFFFDDDEDDDDDDDDDDDCEEDDDDDDDDDDDDD
@22C
CTTGGGTGCCTCAGGAGCAGGAGGTCTCTGGGCTTTACGCTGACGCCGGCGGGGGGCCCGTGTCTTGGAGGCTGCCTTCTTCGGAATGTACACTGGCTGCT
+
8=??DD=ACD?CFBAGB?AFDG@EGIG@GAGID;BGIEEEEBF@@AFBE>C=5@8B555&&)28:AAB3+8(+8<?(4:::(8>22(++:4>(+:8232(+
@22D
TCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCT
+
CC@FFFFDHHHFHIJJIIGIJFII?BGHIGIIIJIJHIIJIJIIIJJGGGEIJIIIIIIIGCEEHFFFFDEEEEE@CDDECCDCCDCDBBBDCDDDDDDBC
@22E
CTTGGAAAAACTCTAGGAGAAGGTGAGTTTGGAAAATTGGTTAAGGCAACGGCCTTCCATCTGAAATGCAGGGTAGGGCACGTAAAGGTAGCCGTGA
+
:1:2?AAA+A)+22+++?A<7+32+++2211)11?=*7**:):?*73=0((''5:A=)7)7))))=7)))7('(((((((('((,(,,5(((()09(
@22F
TTCAGAAAGAACTCAATGTACTTAAATCAGAACAGGACTTGATTAGAGACCAAGGATTTCGTGGTGATGGAGGATCAACCACAGGTTTGTCTGCTACCCCC
+
@?@DFFDDFFAFBFHIIGCIFHHIIIGEHIIGGGGADDHIIGF?BFHHIIIIIGIIHHEBHCCG=CGHIHIHGHHFFFFF?CABB>AC??CCCCCDDDDDD
@22G
CTCAGAAGTGCCTAGCTGCCACTCCATTTATATGAGGCAAGAAGGCTTCCTGGCTCATCCCAGCAGAACAGAAGGCTGTATGTTTGAAAAGGGCCCCAGGC
+
CCCFFFFFFHHHHJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJIJJJJJJJHHHHFFFDFEEFEEDEDDDDDDDDDDDDDD
@22H
GTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACA
+
CCCFFFFFHHHHHJJJIJJJJJJIJIIJJIJJJJJJJIJJJIJJJJJJJIJJJJJJIJIJJJJJJJJHHGHHFFFFEEEDDDDDDDDDDDDDDDDDDDD
@22I
ATGTGATTGCCGGCTCCTCCAAGATGAAGGGCTTCTCGTCCTCAGAGTCGGAGAGCTCCAGTGAGTCCAGCTCCTCTGACAGCGAAGACTCCGAAACAG
+
1=;ABD>;DD<DAEEABD?EDED9EBE<DDDD@BBDD?DDDDEICECEEDD<8:A=7;??@.;>>AAAAAA>AAA?>AAAAA<;>>;>3:>A<5<>9A?
@22J
CAGCTCCAAGAAGAAACATTCAGACTAGAAGCAGCCAAAGATGATTATCGAATACGTTGTGAAGAGTTAGAAAAGGAGATCTCTGAACTTCGGCAACAGA
+
@@@;DDBAFB;DFB?EB:<<C:<C<<AA9AC9CGFIEDGI>B?FBF*?GBGFCFIE=)8C;@F47@.==;DFEEAE<?;;>A3@ACC;;;5=:'885??9
@22K
CCCCAATTGAAAAGAGAAATAAGGTTAATGAAAAACAGAGAAGCTGCTCGAGAATGTCGCAGAAAGAAGAAAGAATATGTGAAATGCCTGGAAAACCGAGT
+
CCCFFFFFHHHHHJIJJJJJJJJJHIJJJJJJJJIIJJJJJJJJJJJJJJJJJIJJGHIJJIIHHHHFFFFFEEEEEEECDEEDDDDDDDDDDDDDDDDDB
@22L
CCTGTAACTCCTTTCCTCCTTTGCCGACGATGCCAAGGGAAGGACGTCCTATGTACCAACGCCAGATGTCTGAGCCAAACATCCCCTTCCCACCACAAGGC
+
??;BDD?,ADD8A:ECE@;CEE@E4C?FEDCCDID*?DDDCDDDDA44ACEI;7?CCC=?5=?98(5>AAAAAAAA>?9=?AAA<><>?A?>??<<?>?<?
@22M
GTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTAC
+
@@CFFDFFHGFHFEIJE@BHHGIHGFCEGIJJEGBHGGIGJJGHIGEGIJGGCHEHGGHIIIHHHEEFE@>DEEEDEEDBDDDDB<?ACCDDD?BDDDADA
@22N
CTGACCCCGAGCAGCGGCCCCTCCGGTCCCCCCTGGACAACATGATCCGCCGCCTCTCCCCGGCTGAGAGAGCTCAGGGACCCAGGCCGCACCAGGAGAAC
+
CCCFFFFFHHHHHJJJJJJJJJJJIJJIJIJJHHFFFFFDDDEDDDDDDDDDDDDDDDDDDDDDDDDDCDDDDDDDDDDDDDDBDDDDBDDDDDDDDDDDD
@22O
AAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTAC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJIJJIJJJIIIHHJJIJJJHFGHFFFFDEEEDCDDDDDDDDDDDCDDDEDDDDDDDEDDDDDBD>CD
@22P
CTGACTAATTCTAAGCAAAAAGAAAGACAGTCTTCTGAAGAAATAAAACAGTTAATGGGGACAGTCGAAGAACTTCAGAAGAGAAATCATAAAGACAGCC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJIJJJJJJJJJJJJJJJIIJJJJJJJIJJJIJJJJIIJJHIJJJGHHHFFFFFFEEEEEDDCCCCDDDDDDDDDD
@22Q
TTTGAAGAAGGGTTCCACAGACCAGGAGAAGATTGAATTCCTGAAGGAGGCACATCTGATGAGCAAATTTAATCATCCCAACATTCTGAAGCAGCTTGG
+
CCCFFFFFHHHHHJJJJJIJJJJJIJIJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJIIJJHHHHHHHFFFFFEEDDDDDEEEDDDDDDDDDD
@22R
CCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGG
+
CCCFFFFFHHHHHJJJJJJJJJJJJIJJJJJJJJJJIJJJJJJJJJIJJJJJJJJJJJJJJJHHHHHHFFFFEDAEEEDEDDDCDDDDDDDDDDDDDDDDD
@22S
CAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJIJIJJJJJJJJJJJJJJJJJJJJJJIJIIJJJJJHHHHFFFFFFEEEEDDDDDDDDDDDDDBDCDDDCEDDD
@22T
TGGAAGTGGTGCAAACAGAAAACCAAGTCATACCAGTGCTGTCTCAATTGCAGGAAAAGAAACTCTTTCATCTGCTGCTAAAAGTGGTACAGAAAAAA
+
CCCFFFDDHFHHHJJJJJJJJJJJJJJIJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIHHHHHHFFFFF;AE>CCEEDDDDDD
@22U
GCCCGACGTTGGGGCATTCAGAAAAACAGGCCAGCTATGAACTATGATAAACTTAGCCGTTCACTCCGCTATTACTATGAGAAAGGAATTATGCAAAAGGT
+
CCCFFFFFHHHHHIJJJJJJJJJJJJJJJJJJIIJJJJJJJJJIJJJJJJJJJJJJHHHFFFFFEEEDDDDDDEDDEFDDDACDDDBDCDDEDDDDDDDD>
@22V
CAACGTTTTATGGTCCTTTACTCACCTTGGTTGACCTTGTAGACCTGTGTGTAGATATTTCAAAAGGCTGTGTCTACTTGGAACGGATGCATTTCATTCAC
+
@@@DBBDDHHFFDFHGGIGIIEHGABEHGG<CEH@BGHG?D@DB<@BDA999DF>FCBDH>FHHB>D=FCEGEH>E??EEEHFFBAAA>BDDEDCDED@C:
@22W
GGAAGAAATGAGGGTTACCTATGGGACTGAAGGACTGCAGCAGTTACAAGAATTTGAAGCTGCCATTAAACAAAGAGATGGCATTATAACCCAGCTCACTG
+
@<<DDDADFHGFDBGGHFEGGHIGIFGBHIGIIIICCGGHICGFHGIGIHDHEHEIGGIIIGHGGGHIIIIHHF>??D3?D>@CCEEDDCCBBA9>@@CCC
@22X
CGAGAGGGAGACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTAC
+
?@@BB?D??DF?D:EFH?8?CD8BEAB?GBG7BF7@A@FC;CHFHHHEDB?9>:BCBBBB?C5>@>4@CCC@C:AC@9<<:>CCA@>@<BB??<@B??C
@22Y
GTGATTTGTTTGAATTCAGATGACATTATGCCAGTTGCTTTAATGGAAACGAAGAACCGAGAAGGGTTAAACTATATGGTACTTGCTACAGAATGTGGCC
+
@@@BDDADDFHHHBHG<FFIAE>E@FHGHGI>HHIH<FGGIIEHCEGHGGC@DGEFHFGEH6BHIEHHEEEDEEDDEECADACD>CC@ACCC>@@CDCBB
@22Z
CTTTGAAGTTAACTATCAAGAGTTACAAGAGGAGTATGCTTGCCTTCTCAAAGTAAAAGATGATTTAGAAGACAGTAAAAATAAACAGGAATTAGAGTAT
+
@?@DDDADFFDHFEEGGGDHGG:FB:CHG@CB@?19?FHEHADGGGIGIIIIGHEHGICEICHI@BBGGGIA@ADDGHIGHFHHE>@CBECCC@CAC3;>
@230
GTGGGATTCTGTTACTCTATCCACACTGCAGATTATTGGACTTGGCACTTTTGAGCGTGGAGTAGGATGCCTGGATTTTTCAAAAGCAGATTCAGGTGTTC
+
@@@FDBDFFBFFHIIIGGHGIIIIIEBHHHICCDGGGIIHCGIIIIGEGIIGEBHHG:FGAH=EHHCCEAEEHHB@@BBC@CCCCC=CC?@C;@CC@C>@>
@231
TTTTCTTCTGGACCTGGAGCGGCAATTCACTAACAAGAAAACAGGGAATTTTTGGGAAATATGAAAAGCCAAAATTTGTGCAGTGTTTAGCATTCTTGGGG
+
?@<B1BD8:C??A+2CD9A@EF8DEBFEFF49:9BFGBFFIEE9BF5CAAFEFFFEA>?B;?@)6>;;@>?;;?<>@A(5@;>AB@BBB4:@BBAAABA?9
@232
TGACTGGACAGTTACCTTATTCAAACATCAACAACAGGGACCAGATAATTTTTATGGTGGGACGAGGATACCTGTCTCCAGATCTCAGTAAGGTACGGAGT
+
@@=DD?DDFFHFHGGGFGGGGHGIIH3CF@>FHE;:C;F8?;D@DFF@BGGIICHGGG@DH=6@E=B=@@>CCACC>CCC55:,>C5>CDCCC5@:95<B2
@233
CTTCGGACTGATGCGGCCCGCAGAAGAGGAGGGAACAAAGAAGCTGGGCGGGAGGCCGGCAATGCTTGAGAACCTCTGGAAGCCCATGCAAGCAATCATC
+
0((-(((-0..)9)(((--(((00)).9((('''(-(.(..()).).((,,&&&&((&&)05(+(2(++(+((((+2+(+((++286;(++2((+(2(((
@234
CCTGACCGGGCCTTCCCAGCTCACCTCCCTCCATCGCAGTCCATACCAGATAGCAGCTACCCCATGGACCACAGATTTCGCCGCCAGCTTTCTGAACCCTG
+
@??BBDDDHDFHHIGIIBBGE@FCBCFGI@B?BB?FDGEBBF=FE@@CHEG=@CHEEHFDFFFCAEECCCCCCB?CCCC<@B9@BCBBAC@@C>ACCB@A<
@235
CACGGGCCCCCCGCCGGCGTCAGCGTAAAGCCCAGAGACCTCCTGCTCCTGAGGCACCCAAGGAGATCCCACCAGAAGCTGTGAAGGAGTATGTTGACATC
+
;@<DBDDDA<AAH<FHFHHGGEFCDDFDDDE@DDBD@DDDDDDDDDCDDDDC?@B?BDDDBB??BACCDDCBDABBDCCCD@A>:@CAA9?CD:ACCDDDC
@236
AGCAATCAGGTGGTCGTACAAACTGCATCAGGAGATATGCAAACATATCAGATCCGAACTACACCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATGAC
+
CCCFFFFFHGFHHGHIHIJJJJJJJJJJJJJJIJJIJJJJJJJJJJJJJJJJJJIJIJJJIIIJJHHHHHFFFFFFEEEEEDDDDDDDDDDDDD?BDDDED
@237
CAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTG
+
CCCFFFFFGHHHHJIJJJJJJJJIIIJJJJJJJJJJJIJJJJEHIJJJJJIGIHHHHFFFFDEEEEEDDDDDDDDCDDDDCDDDFDDEDDDDDDD>CCCDD
@238
GGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTT
+
@@@FDFDDHFFHHJE@EHGEHIJJJIGIJJJJIIJJIGIEHHIGGBHGGIGJEGGGHIJBEHEEHIGCHHEHFFDFFFEDDBDD?BBBDDDDEDDDDDDD
@239
CTACTGTAGAGCCCACACCTGGGAAAGGACCTAAAGGTGTATATCAAATCAGCAAACAAATCAAAGCTCATGATGGCAGTGTGTTCACACTTTGTCAGATG
+
@@@?BADD??DDFBAAEFEGHGEIIIIFIIIDH?9?D9B:0?F>DBF?FDBD>DCHGGCDHIGHHG=EC>CEAEE>CDD;>.;>>>CCCACCCCCA:@>@C
@23A
GCGCCTAGAGGGAAAGCAAGAGGGAGACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGC
+
<<<9>;:><)8=(.8;=).29@>-<??<;;/36??7?>?;97)555-:??;(.339;<<<><:(((',55<220:6:<5::26::;==;/6;<726(57
@23B
GTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGC
+
@?@DDDDDF:?>BHII@HH@3FFEHIBGEGGHHEGGGHICDF;GEDDBFDGCGC@H:DCEHAA;AHE;B=CC>@C@;>C@3A;A>>ACC???5:94?<8<?
@23C
TGATGACTGGACAGTTACCTTATTCAAACATCAACAACAGGGACCAGATAATTTTTATGGTGGGACGAGGATACCTGTCTCCAGATCTCAGTAAGGTACGG
+
?@?DDFFBFFFHH=EFBH@HHIEGCEDHHG@G9CEGIHAGGCBFDCFCGGEGIIII9FEIBFCE@@EA>BBEA@CC@((53>CCC3>>>:>>@A:@@>@&5
@23D
ATTTAAACTGATTGAGCCTGAAGAGGTGGCCCGACGTTGGGGCATTCAGAAAAACAGGCCAGCTATGAACTATGATAAACTTAGCCGTTCACTCCGCTATT
+
CCCFFFFFHHHHHJJJIJJJIJJIJJCGHIIIJGEIHIIJJJJJJJJIJJJJHHHHFFFFDDDEDDDDEDDDDDDEEDDDDDDDCDDDDDDDDDDDDDDDD
@23E
CGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCA
+
==+ABDDD1ACFDFEGFIFE?3FCG)?FEFBEA@FFEEICDFIEIII.=F<@DE;CC=E@<?@;@?@BBB??BBA>A@BBB@BABB7@BBB??B?8?B?
@23F
GCAAATTCAACCACCAGAACATTGTTCGCTGCATTGGGGTGAGCCTGCAATCCCTGCCCCGGTTCATCCTGCTGGAGCTCATGGCGGGGGGGGGAATCACC
+
??=DDDDDFHFHF@FBDADHBFHBAE@CE@EFDGGGGGG?@BGIG==F@FGIGGHDHFHHD:99?A@CC@>3@@@AB<<ACC>ABBB-559&&&&&(+(((
@23G
GGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATC
+
@@@DBDDDHDHFFGBBGHGDEHIGDHI9BDE@DFGFE;/?FF>FCCGHGHFEE@;FCAE@AEEH<DDFBAECE;;===A::>??B:@A:::@@@?C@A?C>
@23H
GCCCGGCGCTTTCCCCGCAAGATGGACGGTTTCGCCGGCAGTCTCGATGATAGTATTTCTGCTGCAAGTACTTCTGATGTTCAAGATCGCCTGTCAGCTCT
+
@C@DFFFFHHHHDBHIIEGHHEGIIJGGGAGIJDEEEDD@BCCCCDDDECDDDCCDEDDECACDDDDDACCDECCD<>>CADDDCCDDBBDBB:>CCDCDD
@23I
CACAGATTTCGCCGCCAGCTTTCTGAACCCTGTAACTCCTTTCCTCCTTTGCCGACGATGCCAAGGGAAGGACGTCCTATGTACCAACGCCAGATGTCTG
+
@@@DFDDDFHGHHIIIIGFGGGGGIIGHIIIIEGGHGFGIGGIIIIIFGEHHEHIBHB7?ACAABBB??BCBBB?@BBA@C@BBCCCBCCCBB?@C>C@C
@23J
GGAGAAAATTCTGGAGTTTCTGCTGCTGTCACTTCTATGTCTGTTCCAACTCCCATCTATCAGACTAGCAGCGGACAGTACATTGCCATTGCCCCAAATGG
+
CCCFFFFFHHHHHJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJHFFDEEEEFEDDDDDDDDDDDDDDDCC
@23K
GGGCAACAAAGATATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGACTATGCACCTTCTT
+
+++22+?<A+++2+,2+<@A+3+<<<<=>?3353AAB3=*00?A>?>ABA===A((98>>;AA>AA)..>AA).7).(6(3;;;''3'&3(3((+33(5:
@23L
GAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTC
+
CCCFFDFFHHHHHJJJJJJIJJJIIJIGGHIJJIJJJJJJJJJHJJJJIJEIHHHHFFFFFFECDDDDDDDDDDDDDDCDDEDDDDDDDDDDDBDDDDDDD
@23M
GCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCT
+
=;1<A??A@<7<+2<22@<<??CA<3A9@@1@=AA7?=7?0?00?;=;=B<A=BB>B3)8>>3;7.>>2)-55;,33,995;????:?5(,,33:(3;<=3
@23N
GTTTTTGGTAGCTCTTCTGGATGACCCTTCAAATTCTCATTTTATTGCCTGGACTGGTCGAGGCATGGAATTTAAACTGATTGAGCCTGAAGAGGTGGCCC
+
@@@FFDFDHDHHFHGIJGIJFJJJGIJDGHGGBGEHIIJJJGGIIGGGIICGHIIEE=EAHHGEEHHCADDFFFFCA>CCEDDCCCDCDDCDDDD:?BBDD
@23O
CGACCATCACCAGCTGAAAAGTCACATAATTCTTGGGAAAATTCAGATGATAGCCGTAATAAATTGTCGAAAATACCTTCAACACCCAAATTAATACCAA
+
@@@FFFFFHHHHFGJIJJJJJHDHHIIJJJJJJJJJIJJJJEIJJJJJIIJHIJHIEHIIIJIIJIHIJJHHFDFFFFEDEEEEDDDDDCDDDDEDCCDD
@23P
CACCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATGACATCTCCTGTGACTCTCACCTCTCAGACAACTAAGACAGATGACCCCCAATTGAAAAGAGA
+
CCCFFDFFHHHDFGGIJIJJJIGHIIJFJIHCHF?FIIIGIDBDHIJIDHIDDF@DFIJJIIIJDEDGE6=DDEEEEEFFFFFFFDDD@CCDCCDDD?CC
@23Q
AAATGAGTCAAAAGATAGAAACCATGCAGTTTGAAAAGGACAATTTGATAACTAAGCAGAATCAATTAATTTTGGAAATTTCAAAGCTAAAAGATTTAC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJHIJJJJJJJJJJJJJIJJJJJJIJJJJIJJIJIIJJIJJJJJJJJJJHHHHHHFFFFFFEEEEEDDDDDE
@23R
CTGCAGATTATTGGACTTGGCACTTTTGAGCGTGGAGTAGGATGCCTGGATTTTTCAAAAGCAGATTCAGGTGTTCATTTATGTGTTATTGATGACTCCA
+
CCCFFFFFHHHGHJIIIIJJJJJJJIIIDHIGEGGCHHHIJHIJIIJIJIIIIJJHIIJIIIIGGGHHFHH>EBDFFFFEEFECCACCDCCDEDEDDDCD
@23S
GACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACT
+
@@@FFFFFHHGHGIJIGGIJIIIJJJIGIJJJIIIIIIGJJJJJIJJIJIJIIIJJJIIJEEEBDFFFEEEEEEDDDDDCCCBBDDDABCBDDDCDCCDDD
@23T
ATTTGAAAGCTGAGATTGTTTCTGCATCTGAATCCAGAAAGGAACTAGAATTAAAACATGAAGCAGAAGTTACAAATTACAAGATAAAACTTGAAATGTT
+
CC@FFFFFHHHHHJJJIJIIJJJJIIJJIIJJJJJJJJJJJIIJJIJJJJJJJJJJJJJJHHIJJJJIJHIIJJIJJJEHHHHFFFFFFCEEECEDDDCD
@23U
GTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGAT
+
???DDDDDHHA?FE@HII@?C?EGGHICG?CFGGC@DF@FGHII><??@8DHICGI@GGA@EH@EA=EC@DEEEEDCC@C@A;?A?B?BB@B@CCDD:@AA
@23V
CCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAG
+
@@?FDFDADFHBBDGF+CFHCCBE>F@AF4ACF=:C@;D1??)0BB9?*9BFD@GH<<83(=;@DHCEHHH;EFDBBC>@A>C?CC?@CCCCCCC5>
@23W
TCTGGACCTGGAGCGGCAATTCACTAACAAGAAAACAGGGAATTTTTGGGAAATATGAAAAGCCAAAATTTGTGCAGTGTTTAGCATTCTTGGGGAATGG
+
@@@DDBEDHD>FHIIGGGGHG@BDDEIGHGICHGICHEGGBG@GHHIIDHC@CHFHGHFCDFFCEEECCCCC@CADC:@CFCCCCCDC>CDCCB@BB?:A
@23X
CCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGAC
+
@@;1BDDDDFFF>FFG;<<@:?EFBC*:**::DAE<?0BBFFF)/BF<D)B)8BCFF;C=)=);@AE;A;;2;BD@>;9?@'',5(59?BDBDDBBBB59
@23Y
AAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGT
+
@@@FFFDEBDFHDHIGEHEIGHGGCHGII@FGGIGHGIJJIGHGGIIGGBDDGIGIIGIIBEEEECE7??@CECDCDDDDBABABBDD>B?@CDC>CDBB+
@23Z
CTGACCGGGCCTTCCCAGCTCACCTCCCTCCATCGCAGTCCATACCAGATAGCAGCTACCCCATGGACCACAGATTTCGCCGCCAGCTTTCTGAACCCTGT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJIIJJIIJJJJHHHHHFFFFEEEEEDDDDDDDDDDDDDDDDBDDDDDDDDEDDDDDDC
@240
AGCCTTCAAAAATGAAGTAGGAGTACTCAGGAAAACACGACATGTGAATATCCTACTCTTCATGGGCTATTCCACAAACCCACAACTGGCTATTGTTACCC
+
==@DDD?BFFFFBAEDE2C?H?<<ACH?ED9<DFCFEFFFDGII<BFH>B8BFCH@AHGGGG>CGGGECE?EC?=CBDECC===BBCCC99:>:>;@CACC
@241
GGGAAAGCGAGAGGGAGACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGG
+
?@<ADD;DHAD1CFH8AGHIGGIG@FGBDHIIIIBAGGGII;AHEEEECCCCC>AC?B?BBBCBBBB>CCCCDCACAC@CC@CCC8?CCCC9A9@><B@8?
@242
ACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATAT
+
?@?DDDFDDADFHIIGIICEIHIII>GGGB@BHDHIFGGFHHIIGIIEHFBDGGGHIIIIEGIBHHGEFC@CBCECACE@>@A?=A?C>>CACCACCDCC
@243
CGCAGAAAGAAGAAAGAATATGTGAAATGCCTGGAAAACCGAGTTGCAGTCCTGGAAAATCAAAATAAAACTCTAATAGAAGAGTTAAAAACTTTGAAGG
+
+=<D:@DBDDDDDAEIEEB@D?C>FFI9<2??E<EDEIDBDDID=B<?</=8==BDEII;.@CC@DA3=?AD37?@3;.>;6>@AA>DAAA?>5>5>:(5
@244
ATCAGATCCGAACTACACCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATGACATCTCCTGTGACTCTCACCTCTCAGACAACTAAGACAGATGACCCC
+
;@@D:BDBFHBHHHIBEGGGEHHH<HHH@H<BGHDGEGHEIDFG>DFGIIE>@<CHI>8=F;;@>C@=)@A:AE;A@@B;;@AC6>CCCAC>?:>>A@@?B
@245
AACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACT
+
<@@FFADD?FFHHGGIIIICHHGIIEI>BGABHHHII>BFHGHIG>?DGGECDCCCGDE@AFCDGIIHEEHDDDDFCDC@ACDDC>CCAAC>ABDD=@B
@246
GAGAGATATGTCTACAAGTTTGTGTGTGATCCAGAAGCCCTTTTCTCCATGGCCTTTCCAGATAATCAGCGTCCACTGCTGAAGACAGAC
+
@@@DDDFFHHHHBHGGHI@EJGIGIGCGHEIGDGIJGGDEHEIEGGGHIIIJGHDGIEDCC@<@C>FCG;B5CBCEACBBCDD;;3>C??
@247
GAGAATAAAAAAAGCAAAGCCAAGGAACCTCCTCCTAAAAAGACGAAGAAAAATAATAGCAGCAACAGCAATGTGAGCAAGAAGGAGCCAGCGCC
+
@@BDFFFFHHHHHJHIHIIIIJJJJGIJGGIGGIIIJJJIGHICGHGIGJJGHFHFFFFFFFBEEA?ABCDDD>CCCDDDDDDDDDDBDDDBBBD
@248
TGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCAC
+
CCCFFFFFHGHHHJJJJIJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJHHHHFFFFFDDDDDDDDDCDDDDDDDDEDDDDDDDDDDDDDDD
@249
TCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATG
+
CCCFFFFDHDFHHGIFHGIIEHJJJGGHHGGIFDGHJIIJ;FGIGHIJIJJCHFFHFFFEFDFEAEDDDDDDDDDDDCCCCCCBDABD@BDDBDDBBDDDC
@24A
GCCTTCCCAGCTCACCTCCCTCCATCGCAGTCCATACCAGATAGCAGCTACCCCATGGACCACAGATTTCGCCGCCAGCTTTCTGAACCCTGTAACTCCTT
+
@@@D=ADDF<FFFEIBDAF;FFFFIIIIEDCFGGDGECA:FBFFCEFB@BDFIF@=@;7=@C=AC>7=ABDD@?B:2;@>@BAAADBB?@BBA:AAA>3@@
@24B
GGAATGTATCGGGAAGGACCCACATACCAACGGCGAGGATCACTTCAGCTCTGGCAGTTTTTGGTAGCTCTTCTGGATGACCCTTCAAATTCTCATTTTAT
+
@@?D?D=B?BFHHI>EG:<AFHID@F@GBFHB@6?;FH8=7=7AEE?7)).;>>;(;?C@C=B@5>:AC::A44:4(>::>@?9A<>CA@:@CC>ACC@@C
@24C
GCGATTCTTCTCACATAGCAACAAGTAGCCTCCATGCCAATCATATAGAAAAGCCCCCGCCGGGAAAAAGAAAACCGACTGAGGACACCACCAATCGGAGC
+
-((2(8))))))))))2))))((.)))))))).)2))))26).))))))).))(((--''''''',9(('(((((,&&&&&+((((+(((((+2(2(&+&&
@24D
AAATACTCAGACAAGAAGAAAAAGAAAAGGGTACACTTGAACAAGAAGTTCAAGAATTACAACTTAAAACAGAATTGTTAGAAAAACAGATGAAGGAAAA
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJDGHJJJJJJJIJJJJJJJJIJJJJJJJJJJJJJJJJJJJHHHHHFFFFFFFEEEEDDDDDDDDDDDDDD
@24E
CTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCC
+
@@@DFEEFHDFFHGGIIJIJIGHHIIIGIIJJGIJJJJIIIJJI@FHJJJIGHGGEEFFFFFECEACCEDDDDDDDCCDCCECDDDDDDDDDDDDBBDDDD
@24F
GGAAACCTCAAGCTGAGAAAGTTGATGTGATTGCCGGCTCCTCCAAGATGAAGGGCTTCTCGTCCTCAGAGTCGGAGAGCTCCAGTGAGTCCAGCTCCTCT
+
@@@DFFFFHGHGHIGDHEHGGEHBFEIHEHIGIIIIGIGIHGGIIIGIIIIICGGIIEG>DGHEHFFFEBD;ABBBBBBBCCC>CACCCA>CCCCCCCCCA
@24G
CTTCCTGGCTCATCCCAGCAGAACAGAAGGCTGTATGTTTGAAAAGGGCCCCAGGCAGTTTTATGATGACACCTGTGTTGTCCCAGAAAAATTCGATGG
+
@@@D?A;DF?DA??E=A2+:C:A:B?FE+)1*?DFGFEGEFCF@F9?1@BFFDFIF<F7@D7@>CF=7=>3?=7;;6;@=,--5;@?BB@95>>@(>A@
@24H
ACCATGAAGAAGATAACTGTGTCCAGAGGACCCCCAGGCCATCCGTGGATAATGTGCACCATAACCCTCCCACCATTGAACTGTTGCACCGCTCCAGGTC
+
@@@DDDDDFHBFDGHHIGGHIJIIICHAEEHIIIIIGGBDHGIII?DHGDGGAHFGGCEGEEGEHEHEEEFDEDACCCACCC>CAACAC?8=5<9ACD:>
@24I
CCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTAT
+
@@@?DDBBDFDFFHGHEE9F:DEACG=FB>FGGGDHHIII@FHHBGG@ECHHE??BEBECCC>CCCCDCCCCBBCBBB<BBBBCCC@:??9?BBBBCCCCC
@24J
GAAGGGGGAGGGGGGAGGGGAAGGTGTGTAGGGGGTTAAATGAGGGGGGAAGGGGGAGGAGGGGGAAGAGAGGAGGGAGGGGGGGAGAGGGGGTGGGGG
+
-(((-((((0(-(0&)))0)&&+6(3(+((3((&)&&(((((((((&&&)&(+&))&&&((&&))&&((+((((()&&&&&&&&)&&&+()&&&&&&)&
@24K
CGAGAGGGAGACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTAC
+
B@BFDFFFFHHHHJJJJIJJIJJJIJIJIJJHHIHGJIIJJJHHHHHHFFFDDDDDDDDDDDDDDEEDDDDDDEDDDDDDDDDDDDDDDDDDDCDDDDD
@24L
CGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCA
+
???DDDDFGHHHFIJGIIIJIHII>?@GGIIJIIIIJJGGGIJGIBHIIJIIHGEEHEHDBCDDBABBDBD<AAC;@CDCDDDDDDDDDDDDDDBBD?C
@24M
AATTTTTAGTTTACCACTTAATCTCTTACAGAAGCAAGTGATTTCCTACCCCTAGATTTTTAGTAACACCTTAAAAATGTATTGAAAACAAAAATTAAGTT
+
C@@FFFFFHHHGHJJJJJJJJJIJJJJJJJJIIJJJIIHHJJIJJJJJJJIJIJIIJJJJIJJHHJJJJJJIJJJJIEHCEHHHFFFFFFDEDDDDDDDAD
@24N
TGAGGATGAAGATGGGGATGGGCGGCTTCGGCCCTCACCTGGGCTTCAGGGGGCTGGGGGCGCCGCTTGCCTTGGAAAGGTTTCTTCTTCAGGAAAACGGG
+
@@@FFADFHHDDFHGHIBGHFGIIJJGGIIIIJIJIHHGHGFFFFDC@CEDBDDDDDDDDDDBB>BDDDDCDDDCDDDDD>CCCCC>CDACCCCDDCD>@@
@24O
GCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGG
+
CCCFFFFFHHHHHJJJJJJJJJIJJJJJJJJJJJJJJJJHIJJJJJJJJJJJJHHHHFFFFFEEEEEEEDDDDCDDEDDDDEDDEDDDDDDD@CDDDDDD
@24P
CTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCAC
+
CCCFFFFFHHGFFIIJIJJJGIJJJJJJJJJJIJJIJJIJJJJJIGJICHIJJIJIJDHHJJHHH>DFFDDEEEEEEDDDDDDDDDDDDBDDDCDEDDDDD
@24Q
CGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCA
+
B@BFFDDFFHHHHJHIJJJJJJJJJJJJIJJJIJJJJJJJJIJJJJJJJIIJJJJHHHHGFDDDBDDDDDDDDDDDDDEDDDDDDBDDDDDDDDDDDDD
@24R
ACCAGATAGCAGCTACCCCATGGACCACAGATTTCGCCGCCAGCTTTCTGAACCCTGTAACTCCTTTCCTCCTTTGCCGACGATGCCAAGGGAAGGACGTC
+
CCCFFFFFHHHGHJJJJJJJIIGJJIJJJIIJJJIJIJJJJJJJJJJIJJJIJJJHHHHHHFFFFFFEEEDDEDDDDDDDCDDDDDDDDDDDDDDDDDDDD
@24S
AATGCTTTAAGGTCATATTCAAATATTACAGTTAATGAAGATCAGATAAAGTTAATGAATGTGGCAATAAATGAACTGAATATAAAATTGCAAGATACTA
+
CCCFFFFFHHHHHIJJJJJJJJJJJJJJJJJJJJJJJJIJIJJJJIJJJJJIIJJJJJJJJIJJJJJJJJJJJJJJJJIJIIIIJJJHHHHHHFFFFFFE
@24T
TGACTCTGCGTCTCTTGCTGGGAAGTGGAGCCTTTGGAGAAGTGTATGAAGGAACAGCAGTGGACATCTTAGGAGTTGGAAGTGGAGAAATCAAAGTAGC
+
CC@FFFFFHHFHFIIGDDEHHIGIIEFGFG>DFFHCCDDBHD?BBGHGCFGGIJJIIIJJIIIFBGGHEHCEE>C;@@C@;A.;AC?A?CDDCAC>5>AC
@24U
CCAAGTTCTTTGAACACCACCCAATACCACAGGAAGAGGCGTCCTTAGCAGAGACTGCCCTAACATCTGGATCATCCCCTTCCGCACCCGCCTCGGACTCT
+
@@CFFDDEDFFDHGGIGGCHEGIJIIJJJJIIAHIEHHIJIHJJJIJIIJGG;DEGFFHFEDFFDFECCCCAA?CDDDBCACCDDBBDD@BBDDBDBBDDD
@24V
GGACAAGTGCAAGCCTATGTCCTATGAGGAGAAGCGGCAGCTCAGCTTGGACATCAACAAGCTCCCCGGCGAGAAGCTGGGCCGCGTGGTGCACATCATCC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJIIJJJJJIJJJJJIJJIJJJJJJIJHHHGFFFFDDDDDDDDDDDDDDDDDBD<BDADDDDDDDDDDD
@24W
CGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCT
+
?@@DADDFHHHHFIIJIBEHEGFHIEGGIJJEFGHIGIJFGHIJIGHIJJGDGHGGCFGDGHEGIJHHFEEHFFFFDDDDD=CCD:ACDCDDDDCDDDD@@
@24X
CACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGAC
+
CCCFFDFFDFFHHIJJJIGJGJJJJJIJJJJGHEEHJJGGIJIGHGHJIJIEIIJJIJGGIIJJJJHEFHHHEEFDEDBABDBBBDDCDCDDDCDDDDADD
@24Y
CCTCATTTCATTTGCCAGGCAGATCTCACAGGGGATGCAGTATCTGTCCGAGAAGAACCTCGTTCCTCGGGTCTTGGCTGCCAGAAACATCCTCGTAGCCG
+
;57@5)):?)))94>))2(<.(-=.).):))(((((:=<)))0=)))06(7(<'...)6).(.-:)6),',.3(7((((,7,;(((,,((((+()(2(+(&
@24Z
TATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTT
+
@@CFFDFFGHH?FGGIIDHIGHJFIICDHIJGGGGI@GHIGGGGIJJIHIHIHIICGEHGHIGBHFFDDCEDDDDCCCDCCDDCD>BDDDCDD?<?CD@C
@250
CACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTG
+
CCCFFFFFGHHHHIJJJJJJJIIJJGIIJJJJJGJIIJIJJIJGHIIJIJJJIJJJIIIJIIJIIJJJHHHHHHFFFFFEEEEEDCDDDDBBDDDBDBDDD
@251
CTCCTGTTAGCCAAGAAGAAAGATTGATTTTCTTAGACTCCATTAAGTCCAAATCCAAAGACTCTGTGTGGGAAAAAGAAATAGAAATACTTATAGAGGA
+
CCCFFFFFHHHHGJJIIIHIJJJJIJJIBGIIIJJJJJJJJIGJJJJFIJJJJJJIIJIIJGJJGI>F@CHGGIIGFFEFFCDACEDCEEDCDDDDDDDD
@252
CCATCGCAGTCCATACCAGATAGCAGCTACCCCATGGACCACAGATTTCGCCGCCAGCTTTCTGAACCCTGTAACTCCTTTCCTCCTTTGCCGACGATGCC
+
CCCFFFFFHHHHHJJJJJJJJJIJJJJJJJJJJJJJJIJJJJJIIJJJJJIJJJIHGFFFFFFEEEEDDDDDDEDEDDDDDDDCCDDDDDDDBDDDDDDDD
@253
CTCCCACCAAAAGCATAAAACGACCATCACCAGCTGAAAAGTCACATAATTCTTGGGAAAATTCAGATGATAGCCGTAATAAATTGTCGAAAATACCTTC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJHIJJJJJJJJJJJJJJJJJJIJHHHHGHHFFFFFDDDDDEDDEECCDDDDDDDDDDDDD
@254
TACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGC
+
CCCFFFFFGHGHHIJJJJIJIJIJIIJIJIIGGIIHIGHIIIJIEEHIJJIJIGIIGIGEHH@GGGHHFFFBDEFD@@AECDBBBBBDDDCCDDDDDDDD
@255
AAAGAAGACCCTTCTTATGACTCAGTCAGAAGAGGAGCTTGGGGCAATAACATGAATTCTGGCCTCAACAAAAATCCGTATCAGATCCTGGGCCCGACC
+
@@@DFFDAHHHHHIGGGIIJICHGGHHIHIIEGGDGFGGGEBHGIGFEHIIIGGFGIIIJJIGIEIIHHFHFFFFFEB=ABBDCC>CCC@?B?AB@@BD
@256
CCTGTCTCCAGATCTCAGTAAGGTACGGAGTAACTGTCCAAAAGCCATGAAGAGATTAATGGCAGAGTGCCTCAAAAAGAAAAGAGATGAGAGACCACTCT
+
<?@DDD;B?DA?3A?EEBCFDGB<AEDEFA8CFGHEHIAHCGBF@>BBBHCBBFHCHIG4=CFA;FE)=CCCEHEHHDDBBCC@B?CCC@>ACB?@CBC?C
@257
CCTTCAGATATTGCCAAGTAGGTTTGGGTAGAGGATACTATTTCCTGAATAGTGATAAGCTCACCTAGGGGGGTATGTTTGAATACACATTTGCATATACC
+
((((284)28))))<<93):<39:)89/2;139(9;1)2):=:?8)0.)6=):6)0)0)))9>1(636);5=&&0::(++8(+2(86(+::8:<<<:(222
@258
CCTGTATAACCAATGGAAGTGGTGCAAACAGAAAACCAAGTCATACCAGTGCTGTCTCAATTGCAGGAAAAGAAACTCTTTCATCTGCTGCTAAAAGTGGT
+
CCCFFFFFHHHHHJJJIJJHIJHIJJJJJJJJJJJJJJJJJJJJJJJJJIIJJJJJJJJJJJJJJJJJJJJIHHHHHFFFFFFFEEEEEEEDDDDDD@CD>
@259
GCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJIHIIJIJJJJJJJJJJJJJJJIJIJEIJIJJJIJIHIJHHHHGHFFFFFDDAEDDCDDDDDDDDDDDDDDDDDD
@25A
GAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACT
+
===AAAAA=@CBBAB7ABCBB?AC+?BBCBBBBBBBBBABBBBBBBBBBBBBA=ABBABBBBBBAABAA@@<=?;??;???:??9>9=99,89;<===<<=
@25B
CTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTT
+
CCCFFFEFHHHHHJJJJHIJJJJJIJJIJJJJJJJJJIJJJJJJJJJIJJJJJJJJJJJJJJJJJJGHHHHFFFFDECEEEEDDDDDDDDBDDDDDDDDDE
@25C
TGAAAAGGGCCCCAGGCAGTTTTATGATGACACCTGTGTTGTCCCAGAAAAATTCGATGGAGACATCAAACAAGAGCCAGGAATGTATCGGGAAGGACCC
+
CC@FFFFDHFHHHJJJJJJHHIJJJJJJJIGGIGGIFHHIIIGIJJJJJIJJIJJJJGIIIJJHHHGHHFFFFEEEEEDCDDDCC@CCFDDDBDDDDDDD
@25D
CACACACAGCCGGAGGGCATACTGCATCAGAACCATGAAGAAGATAACTGTGTCCAGAGGACCCCCAGGCCATCCGTGGATATTGTGCACCATAACCCTCC
+
>=<<<?02+27)0?=<):?=<>=BB=B<A>==)=BB<9=))..88ABB477=AB>=7>A;((;=;9=((5;=3592,,52++(+(++(+8(+++33;8;==
@25E
GTCATCTTCATCCTCAGAAGACAGGAATCGAATGAAAACACTTGGTAGACGGGACTCGAGTGATGATTGGGAGATTCCTGATGGGCAGATTACAGTGGGAC
+
@BCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJIIJJJJJIIIHJJJJJIJJJIJHHGJHHHHHHFFFFEEEEEEDDDDDDDDDDDDDDDDCDDDD
@25F
GATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCC
+
CCCFFFFFHHHHHJJJJJJJJJJIJJJJJJJJJGHIIJJJJJJJIJJIIJDHIJJJJJJJJHAHHHHFFFFBDEEEEDECCDDDDDDDDDDDDDDDDDDDD
@25G
GCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACC
+
@C@DFBDDHDHHGGJJGJIJJJJIGIIIGGHIIGIGGHHFHFHHIIJGGDHIJGIGGGIGDHEIIIJIIEEHHDECCFEEDCDADDDBDDBDDDCCCCDDD
@25H
TTGGGAGATTCCTGATGGGCAGATTACAGTGGGACAAAGAATTGGATCTGGATCATTTGGAACAGTCTACAAGGGAAAGTGGCATGGTGATGTGGCAGTG
+
CCCFFFFFHGHHFJIJGIJIIIGIIJJIJBFHIHHIJJJIIGEIIEEFEGEBCHIGIJGIEHIGIEEGGIJGEHH?DEF3>A(>;AB5@;@@3>C?CB?C
@25I
CCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATGACATCTCCTGTGACTCTCACCTCTCAGACAACTAAGACAGATGACCCCCAATTGAAAAGAGAAAT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJHIJFHIJJJJJJJJJJJJIJJJJJJJJJJJJJJIJJJJJIJJJJIJJHHHHHFFFFDDDDDDDDDDDBDCDDD
@25J
CATAATTACATGCGGTAAATCTCATATTTTCTTCTGGACCTGGAGCGGCAATTCACTAACAAGAAAACAGGGAATTTTTGGGAAATATGAAAAGCCAAAAT
+
CCCFFFFFHHHHHJJHIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJHHHHHFFFFFDDDDDDDDDDDDDBDDDDEEEEDDDDDDDDDD
@25K
GTGGAACCCAACGTACGGCTCCTGGTTTACAGAGAAACCCACCAAAAAGAATAATCCTATAGCAAAGAAGGAGCCACACGACAGGGGTAACCTGGGGCTGG
+
??@FDFFFHHFHGGHFJIGGGGGDGDFHIGFIHIGIIEHIGHIIIJIGAHIAGHEHFHHDFFBDFFFE@C@B??BAA@DDBBDDDDD09?ACDABDDDDBB
@25L
CTATGATAAACTTAGACGTTCACTCCGCTATTACTATGAGAAAGGAATTATGCAAAAGGTGGCTGGAGAGAGATATGTCTACAAGTTTGTGTGTGATCC
+
CCCFFFFFHHHHHIJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJBFGIJJJGHHHHFFFEEECEEECEDDCCDDBDDDDDDEED
@25M
TGAATATAAAATTGCAAGATACTAACTCTCAAAAGGAAAAACTCAAGGAAGAACTAGGACTAATTTTAGAAGAAAAGTGTGCTCTACAGAGACAGCTTGA
+
@@CFFFFFGDHFFIJGGEHHIIJIIJGIJIIIJJJJJIJGHHGIIGHEGIJICGGHHGGIJJIIJIJIIIJGIEEHE7?ABEECDFECCDCEDDC?CCDD
@25N
CTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCC
+
CCCFFFFFHHGHHJJJJJJJJJJJJJJIJJJJJJJJJJJJJIJIJJJJJJJJJJJIJIJHHHHHGFFFFFEEEEDDDDDDDDDDDDDDDDDDDDDDDDD
@25O
CAGTAAGGTACGGAGTAACTGTCCAAAAGCCATGAAGAGATTAATGGCAGAGTGCCTCAAAAAGAAAAGAGATGAGAGACCACTCTTTCCCCAAATTCTCG
+
CCCFFFFFHHGHHHIGHJJJIIIJJJJJIJJJJJJJJJJJJJJIJJIJIJIJFHIJIJJJJJIJIJJHHHGFFFFFFEDEDDDDDDDDDDDDDDDDDDEDB
@25P
CGCTTCCTCGACGCCACTTCATGTTCCAGTGCCTCGAGCGCTCAGGATGGAGGAAGACTCGATCCGCCTGCCTGCGCACCTGCGCTTGCAGCCAATTTACT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJHIJJJJJJJJJJGHJJJIIJJHHHHFFFFEEDDEDDDDDDDDDCCDDDDDDDDDBDDDDDDDDDDDDDDDED
@25Q
AGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTAT
+
CCCFFFFFHHHHHIJIIGGHIJJGIHIIIJIIIIGJJIJJJGIIJJIJGHHIGGGIGJDFHEHFDFFDFFDDEECDACCDCDDDCACCCDDDDDDCCDDDC
@25R
GTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGTGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACT
+
?=;A?DBD?C>DDGEBHI9FAFBCACHHCEE@GEHI@*1:<?FHGDB0B?AB>D/===C@A@AG;@E==)?;B<>6,5@>7ACC:><<98?@BBCC<CCA
@25S
TTCTATAGAAGACCCTAACAGTCCAGCAGGAAGAAGGCATTTGCAGCTCCAGACTCAATTAGAACAGCTCCAAGAAGAAACATTCAGACTAGAAGCAGCC
+
8?;DADDBBDFFD:CFEG;CHICFEFBBFB@GEEFFBFDCGCBGIDCFG8?BBF@FFEGEECEFGIIFEF;EC=>BDDDDCB@AAA6>>5@;AB::A929
@25T
CAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGG
+
@@@FDEFFHGHHDGGGGIIIAHIGHFHHIIIIIIJJIJHIJIJGIIJIIIIIIJIJJIIGIIEFHHFFFFF>ADDEEDEDDDDDDDBDCCCDDDDBCCCBD
@25U
CAGAAGCCCTTTTCTCCATGGCCTTTCCAGATAATCAGCGTCCACTGCTGAAGACAGACATGGAACGTCACATCAACGAGGAGGACACAGTGCCTCTTTCT
+
BCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJIJJJJJJJJJJJHHHHFFFFFDDDDDDDDDDDDDCCDDDDDDDDD
@25V
CTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGC
+
CCCFFFFFFHHHGJJIJJIJJJJJIJIJJJJIIJJIJJJJJJEHIGIGIIJIIJIJGIIIHGIJJGFHEFFFBDDECCCEEEDDDDDDDDADDDBDDDCD
@25W
CGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGG
+
CCCFFFFFHHGHHJJJJJJJJJJJIJIJIJJJJJIHJGGIJJJJIICEIIIIIJIJJJHFFFEDDDDDDDCDDDCCDDDDDDCDDDDDDDBABDDDDDEDD
@25X
GGCTAAACAGAATCAAAACTGAAGTAGGAGATAATTGGAGGCTAAAGATAAGCAATTTAAAGAAAATTTTAAAAGGAATCTTGGATTATAATCATGAGATT
+
CCCFFFFFHHHHHJJJJJJJJHIJHJIJIJHIJJJJJJIJIJJJJJJJJJJJIJIJJJJJJIIJJJJJJJJJJJJHHHHFFFFFFFDEEEEEEDDDDDDDD
@25Y
TTCCGATGTTGACAACTATGATGACATCAGAACGGAACTGCCTCCTGAGAAGCTCAAACTGGAGGGGGCATATGGTTATCGGGGAAAGGACTGTAGAGCT
+
??<?DDDDHAFF<B@GH>EF@FH>3CHIGI?EHEG7FHH<F@GIIIIEH9DA=8<B7=))>@DE(/,9?;93>5:>(:::<&50908??1<9<>(>@>CC
@25Z
GTTTCACCCAACAGATGCAAATACCATAATTACATGCGGTAAATCTCATATTTTCTTCTGGACCTGGAGCGGCAATTCACTAACAAGAAAACAGGGAATTT
+
@@@FFFFFHHHHHJJJIJJFCFHHIJIJJJJJIJFIGIJFHIJJJJIJIJJJJJHIJJIJJJIJJJIIJGHFFDDDDCDDDDDCDDDDDDDDDDDDDDDDD
@260
CTTCACAACCTCTCCAAATACACAGACAAACTCCAGAAAGCAAGAATGCTACTCCCACCAAAAGCATAAAACGACCATCACCAGCTGAAAAGTCACATAAT
+
@@<DDDBAF:2CFGIBGD:<<A<AF9CA<ECGD<C@@FGI>GB?GBB?</9DFCFCFI<9=@=DCDEEE>EF?DCC@@AA;=A2?BA>:@BABBD@>@>:>
@261
CACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTG
+
CCCFFFFFHHHFHJJJJJJIIJJIIIIJJJJJJJJIIIIJJJJGGJJJJJJJJJJJJJIJIJJIJJIGHHHHHHFFFFFECEEEBDDBBDDDDDBDDDDDD
@262
AAGGGAAGGACGTCCTATGCACCAACGCCAGATCCCTGAGCCAAACATCCCCTTCCCACCACAAGGCTTTAAGCAGGAGTACCACGACCCAGTGTATGAAC
+
-;9?3(:=@<79>;=(9=))2)..68(-93=(6))).3)9)7;=>?1;8).-;;>?8;739=(.((((,3-(--3((,,,5(,52()00&+(+8+26236(
@263
CTTTGAGGGCCAACAGCCCACCCTTGAGGTCCAAAGAAAATCAAGAACAGAGCTGTGAAACCGTAGGGCATCCCAGTGATCTGTGGGCAGAAGGTTGCTTC
+
@;@DDA7DAADD=AC@B=FEA1CA:9*?F:93?<9?9?D@D<FH@<8=3.))8=38.7.=7@:52;;;@AC@C2>;-;:;3;:>398195<>>8>:?BCC:
@264
AGACAGAAAAATAATTCTGTGGGATCATGATCTGAATCCTGAAAGAGAAATAGAGGTTCCTGATCAGTATGGCACAATCAGAGCTGTAGCAGAAGGAAAGG
+
CCCFFFFFHHHHHJJJIIJHIIJIJJIJJJJJIIIJJJJJJJJJGHGGIJIIIIIJIJJJJJJJJJJHHIJJJJJHHHHHFFFFFFEDECEEDDDD@CDDD
@265
AAAATGTTTATGCGCGGTCGGCCAATTACCATGTTCATTCCTTCCGATGTTGACAACTATGATGACATCAGAACGGAACTGCCTCCTGAGAAGCTCAAACT
+
?;:DBDBDH?FDAGGEH?EHEGIICHIGDF9DFBBFBEHIHIGII:@;@HIGHCF>C@DEEEDEDCCCCCCCCCB=?B?C>CCCC<?AC94>CCCAC@CC>
@266
CTATGATAAACTTAGCCGTTCACTCCGCTATTACTATGAGAAAGGAATTATGCAAAAGGTGGCTGGAGAGAGATATGTCTACAAGTTTGTGTGTGATCC
+
CCCFFFFFHHHGHJJJJJJJJJIJJJJIJJJJJIJJJIJIIJJJJJJJJJJJIJJJJJJFHFIJIJEEEHDFFFCECFEEEACDDCDEDACCDDDCCCC
@267
ACATGATCCGCCGCCTCTCCCCGGCTGAGAGAGCTCAGGGACCCAGGCCGCACCAGGAGAACAACCACCAGGAGTCCTACCCTCTGTCAGTGTCTCCCATG
+
@@CADFFFHGHHHJIJIJJJJIJFIGGGGIAHIICGHIJGIJIHHHHFFFDDDDDDDBBDDDDDDDDDD??B<?ACDDDDDDDDCDCCCD>@ACCDDDCCD
@268
GCTCACTAATGTCGACACAGCTAAAGAATCATACCAAACCATGGGAAACAAATTGACCAAAAAGATGTACGCTTCAAAAATTGCCACCAATAGCCTAGACC
+
(((-24.))222)((-2(<(.@)666;:)).):))):663<)<)..<1:9=1))9)).)73(('-).)...9;=8=(((,35=1;((38(,(((((+((+(
@269
ATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCC
+
CCCFFFFFHHHHHIJJJJJIIIJJJJJJGJJJIIJJJJJJJJJJJJJJJJHHHHHFFFFFFEECEEDDDDDDDDDDDDDDDDDDDDDDDEDDDDDDDDDD
@26A
CACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTC
+
@;=BDADDAHFFHGHGHIBFCH=;FHIGGIIGIBFG@FFCHCCCGADD;@E@CEHECEEEE<.;;@CC?B?=?@CACBA?9<CCCCBBACCCCCCCC:>9A
@26B
GAAAGAACCCCACAGTCCATGTTCAGAAATCGGCTCTGCCTGCAGTCAAGAACAGCCCTTTAAATTCAGCTATGGAGAAAAGTGCCTGTACAATGTCAGTG
+
C@CFFFFFHHGHHJJIJJIJJHHIIIIJJFHGGIIIIIJIIJIJIGGIJJJJJJJIIIIJIJJIGHEHHFFFFFFDEEDEEDCDDDDDDDDEDDDDDDDAC
@26C
GTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGC
+
@@@FFFFFHHHHHJIJJJJJJJJJJHIJJJJJJJJJJIJIJJJJJJJJJJJJJJJJJJJJJJHHHHFFFFFEEEEECCEDEEDEDDDDDDDDDDDDDDDDD
@26D
CCAAGGGTGAGCTGGGGCTCTCCCAAATGCTCCACATTGCCAGTCAGATCGCCTCGGGTATGGTGTACCTGGCCTCCCAGCACTTTGTGCACCGAGACCTG
+
CCCFFFFDHHHHHIIJJJJJJJJJJIJJIJIJJJJGIJJJJJJJJJJJJJJJJJJJIJEHHHHBEBFFFEEEEECDDDDDDDDDDDDCDDEDDDDBDDDDD
@26E
CTCACCTCTCAGACAACTAAGACAGATGACCCCCAATTGAAAAGAGAAATAAGGTTAATGAAAAACAGAGAAGCTGCTCGAGAATGTCGCAGAAAGAAGA
+
CCCDFFFFHHHHHJJJJJJJJJJJJJJIJJJJJJJJGJJIJJJJGHIJJIJJJJIJJIJJJJJJJGJHHHHFFFFFFECDDBDBDDDEDBDDBDDDDDDD
@26F
GGAAAACAAGAGGAAGAAGGGCAGCAGCAGGAGGAGGAAGGGATGTATCCAGATCCAGGTCTCCTGAGCTACATCAATGAGCTGTGTTCTCAGAAGGTCTT
+
?@@DDFFFHHFGDBGGGGEAGHEGIC@GDFDDDE=BFDHIIIIII@@DD@F@DCEEIEH=CHHFFFFFCCE@@ACDCCDCCDDD:AC>;ACEDACDDACCA
@26G
GGTAAATGGTTGCAGTTTTGTGATGAGAACAGGAAAGCCTACAAATTTATTAAGGGAAGAAGAATTTGGTGTTGATGATTCTTATTCTGAACAAGGAGCAC
+
B@@FFFFFHFHHHJJJJJJJHHIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJCGEHHGHHFFFFFFFEEEFEEEDDDDDDDDDD
@26H
GCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGC
+
@@@DDFFFBHHAHGEGGEGEFHIIIJJJGHEFGIIJIJJGIJHEGGGIIIGIIGGIFEHEECGGHHHHHGFFFEBDCACDDDDDDDDCDCDCDDDACCDB
@26I
AGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJIJJJJHJJJJJJJJIJJJJJJJIIIJHHHHHHFFFDDEDEDDDDDDDDDDDEEDDDDDDDDBDDDD
@26J
CCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTAT
+
@@;?;DDD8CFD>GHGFIIIHGDEHGCHGIIIIIIIBH@FGHIIIIIIICAHGIIGDH@GHH>EE@DEECC8=<??BCCC>ACB??BBCB:AA>CC<B0<:
@26K
GACAATTTGATAACTAAGCAGAATCAATTAATTTTGGAAATTTCAAAGCTAAAAGATTTACAGCAGTCTCTTGTAAATTCAAAGTCAGAAGAAATGACTCT
+
?@@DD;DDAB<FA:CC<<AAA3F?EEACCH<HHI>*119?CG?B??::FDGE<B<1BBAG8?.)8=FG>FAH:D=====C==C=A))?;?B7@C;3>665;
@26L
GGCATTCACTATAAACAGCAGATAGATGGTTTACAGAATGAAATGAGTCAAAAGATAGAAACCATGCAGTTTGAAAAGGACAATTTGATAACTAAGCAGA
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJHHIJJIJJIJJJJJJJIJIJJJJJJJIJJJJJJJJJJJIJGHIJJIJJJHHHHFFFFFFEEEEEEEDCDDD
@26M
CGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCA
+
?@@DBDDAHDFHDFBGGGIIAHBGGFGGD<BF?DGHGHIIIIGIIIIGEGGGGIIGCC?ABCC@>BB?;B?BCCCCCA:ACCC@?<BBBB?BBBCCBCC
@26N
CTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGC
+
@@@FFFFFHGFHHJIJJIJJJJIJIIIJJIGIJI@FGIJIIJJIJJJIHIJIJJJIJEIIJGIIEHHEEEFFDFFEEDCCCEDDDDDBDDDDDDDDDCDD
@26O
AGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGAC
+
CCCFFFFFHGHHHJJJJJJIJIHJIIJJIGIJJJJJJJJJJJJJJIJJJHIJJJJJIJJJIIJIJJJJHHHHFFFFFEEEDEDDDEEDDDDDDDDDDDDBD
@26P
CAAGAGCCAGGAATGTATCGGGAAGGACCCACATACCAACGGCGAGGATCACTTCAGCTCTGGCAGTTTTTGGTAGCTCTTCTGGATGACCCTTCAAATTC
+
CCCFFFFFHHHHHJJGHIJIJIGJJJJJJJJIJJJJJJJJJJIJGHFDEEDCEDDDDCDDDDDC?B<CDDDBDADDDDDDDDDDDCCDDDDDCDDDDDDDC
@26Q
GGCTCCTCCAAGATGAAGGGCTTCTCGTCCTCAGAGTCGGAGAGCTCCAGTGAGTCCAGCTCCTCTGACAGCGAAGACTCCGAAACAGGTCCTGCCTAATC
+
@@@DDDADFDDFHGIGGFIIHGHIC?<:EDBFHGHG?FBBGI<CG4BG@F)8=@=CDC=@;EHAH?;BDFDBCDB=@AC>AB@?<>C98:>@CC<<CCCDD
@26R
CCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGCCTC
+
CCCFFFFFHHHHHJJJJIJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJIIIIJJIJJJJHFHHHHFFFFDDDEDDDDEDEDDDDCDDDDDDDDDD
@26S
GCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGT
+
@@@FFFFFHHHHHIJJEHGIGIIIJJJJJIJJJEIJGIIIIJJJJJJGIGIJHIJJIJJJJEEHGIJJHGGFFDEDEEDDCDDDDDDDDDDCDDDDDDDDA
@26T
GAAAAATAATTCTGTGGGATCATGATCTGAATCCTGAAAGAGAAATAGAGTTTAGTGCTTCAAGGGCCAGGCTGCCAGGCCATGTTGCAGCTGACCACCC
+
;1::A+2=2=CDDIA:+<3C+<FB:F@FBDDDEII@499?:1C;D?BDE>0?BD:*0BDD@=BB=;5@@@(@6=AADADDD?A;>>A;>(-;5;55>???
@26U
CTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCC
+
===AA?<7+?AA++?A8?<C07:AAABB<?7?4?A79A=7?>7((==77A)>A;9.77=AA77AA@@@>.((;>====:1,(2:=?;3;991;;38388
@26V
CTGAGACTCCTGCTCAGTGTAGCATTAAGCAGGAACGAATTTCATATACACCTCCAGAGAGCCCAGTGCCGAGTTACGCTTCCTCGACGCCACTTCATGTT
+
CCCFFFFFHHHHGJJIJGHJHIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJIJJHHHFFDEDDDDDDDDDDDDDDDDDDDDDEDDE
@26W
ATTTTCTTCTGGACCTGGAGCGGCAATTCACTAACAAGAAAACAGGGAATTTTTGGGAAATATGAAAAGCCAAAATTTGTGCAGTGTTTAGCATTCTTGGG
+
@?@FFFFFHDHHFGIIFGCGGIJIIIJECHIIJJGIIJIJJJIJIJIIJIJGHEIHHEFBFFFFEEEEECDCDDDDDCD;ACDC>@CCDCDCCEDACDDCB
@26X
CCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGT
+
CCCFFFFFHHDGDIJIGHIGIHIJIJGIJGHIJIGIGIJIICFHIFHIIGGIHAEEHFFFFFFFEEEEEDDDD;CDDCCDDDDBDDCDDDBCDDDDCDDDD
@26Y
CTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJIJJJJJJHHHHFFFEFFEEEEEEEDDDDDDDDDDDDDDDDDD
@26Z
GACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJHHHHHHFFFFFFEEEEEDDDDDDDDDDDDDDDDDDDDDDDDDD
@270
CCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCAT
+
C@@FFFFDHHHHHIIJJIIIIIJJJJJIGIJIGGIIJIIIJIJJIIIJBIIIGIIJFGICEIGGEHFEFFDEEDCEDEEDB?BDBDDBDBDDDDB>C@CDE
@271
CCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTC
+
CCCFFFFFGBDHGGGIIJIJJIJEGIJGGDGHGCCCEHIJJFHIIIJGIJJIIIJGGHIGIJJJHGHCEEFC@BDDCDD@ABBB>BB?CDDDECDCCDDCC
@272
CCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTAT
+
CCCFFFFFHHHGHJJJJJJJJJJJJJJJJIJJJJIJJJJJJJJJJJJJIJJHHGFFFFFEEEEDDDDEDDDDDDDDDDDDDDDDDDEDDBDDDDDDDDDDD
@273
CTCCGAGGACGGGCTGCATAGGGAAGGGAAGCCCATCAACCTCTCTCATCGGGAAGACCTGGCTTACATGAACCACATCATGGTCTCTGTCTCCCCGCCTG
+
?1+A;D<?@C?D<FFFIDFF?9DG@G;?FBBFFFC@DF)=FF;=7CECE3=A/5<1;5=(,,,5?BBB3;:55<<82>@A44(+::ABB+4>:4><5&&)2
@274
CGAATACGTTGTGAAGAGTTAGAAAAGGAGATCTCTGAACTTCGGCAACAGAATGATGAACTGACCACTTTGGCAGATGAAGCTCAGTCTCTGAAAGATG
+
CCCFFFFFHHFHHIJJJJIHHIIJJJJJJJJJIJJJJJJJJJJJJIJJJJJIJJIJIJJIJHIJIJHHHHHFFFFFDCEEEEDDDDDDDDDDDDDDDDDD
@275
GCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGG
+
@BCFFFFFHHHGHJJJIJJJJJJJJJIJJJJJJJJJIJJIJJJJJJJJJJIIJJJJIJHHHHHGEFFFFECDDDDDDDDDDDDBDDDDDDDDDDDDDDDDD
@276
AACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCC
+
CCCFFFFFHHHHHIJIIJJJJJJJJJJIJFGIHJJJJJJJJIJJJJIJJFHIJJJJIJIJJJJJJJHHHHHFFFFEEEEEEEDDDDCDDCDDDDDDDDDDD
@277
CGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCA
+
;??DDDDD;FFHHGEGBHIGHIHHIDGGIGGIGDGHIGGBBCGGHGIAAFFHDEHHGHHHFDDDDD?ABBAACDDCCCCCDCCCC<@B>BAB@BABBDC
@278
CCAACAGATGCAAATACCATAATTACATGCGGTAAATCTCATATTTTCTTCTGGACCTGGAGCGGCAATTCACTAACAAGAAAACAGGGAATTTTTGGGA
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJHFFFFEEEEEEDDDDDDDDDDDDDDDDDDDDDDDD
@279
CAAGGATTTCGTGGTGATGGAGGATCAACCACAGGGTTGTCTGCTACCCCCCCTGCCTCATTACCTGGCTCACTAACTAACGTGAAAGCCTTACAGAAATC
+
<??DDD3B>D8+<:2<C>@AEE7@FEE<E8;?11B):BDDEDED4??DCCAA445;6;>;5;>AA(;<95:>>:A>>A>:3+((8<A>A<434:+:>AA44
@27A
GTGCCTCTTTCTCACTTTGATGAGAGCATGGCCTACATGCCGGAAGGGGGCTGCTGCAACCCCCACCCCTACAACGAAGGCTACGTGTATTAACACAAGTG
+
@??DDFFFHGFHHIIIHIGCHGGGHAGIJIJIJEHIJJIGIIIGIIIDIIEEHF@DEFFDBDDDBDDDDDDDDCCBBBD@BCACD2<9<@B>CACCAB@AC
@27B
GTGAACACATCTGCCTCATATCGGGACACCGCTTCAGAAACGGAGAAGGAAGGCATCAGCTATTTCTTAAGGAAACAATTCCGAGGGAAAACATGTGCATC
+
7((2-9.).)<)))))2)));;((((-(.-((((-)))0)0(7;/'.86=)((.6;;))))):).:=1((.:7;<4-(((7(('')&&(8(++(((+(((+
@27C
CAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCT
+
CCCFFFFFHHHHHJJJIJJJJJJIIJJJJJJJJJJJJJJJJJJJJJJJJJJJJIIIJJJJIIHHHHFFFFEEED@CDDEEDEDDDDDDDDDDDDDDDDDD
@27D
TGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGG
+
CCCFFFFFHHHHHJJJJJJJJJJJIIIJJJJJJJIJJIJJJJIIJJIIAHGHIJHGFEEFFDBEDEDDDDDDDDDDDDBDD:ADCED@CCDDDEDDDDC@D
@27E
CACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGAT
+
CCCFFFFFHHHHHJJJIJJJJIJIJJJJJJJJIJJJHIJJJJJJJGGHIJJJJHIIJJJJJJHHHHFFFFEDEEDDDDDDDDEEDDDDDDDDDDDDDDDDD
@27F
CCTAGAGGGAAAGCGAGAGGGAGACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGC
+
@@@FDFFFHHHHDGGGHGGIGGEEGGIBHHFGEGIJIGE@@EHFHFB?DCCDCDBBCDDD:A?@=@DDCBBDBDCCC@@ACDDCDD@CCCCB<:CCCCCDD
@27G
AATACCTTCAACACCCAAATTAATACCAAAAGTTACCAAAACTGCAGACAAGCATAAAGATGTCATCATCAACCAAGAAGGAGAATATATTAAAATGTTT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJHIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJHHHHFFFFFEDCCCDDDEFEFDDEDDDE
@27H
GGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACAC
+
1==DDDDB2CDD:C?BD<@FEFEEEIC8CFECEE;8):C8DD@C8?DD9DEAD9BCCEC7AAC=7;A@A;CDA;@@A:=>6>>=A>?A:>A>AAA:55(9
@27I
AAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACC
+
CC@FFFFFHHHHGJIJIIIJIIIIJIIJJJIIIJJJIJJJIJJIJJGIJIJHHHFFFFCFEEEEEEEDDDDDDDDDDDDBDDDDDDDCDCDDDDDDDDDDD
@27J
AAAGCTTTCCCCCTCCTCTGATGATTAAACAGGAACCCAGAGATTTTGCATATGACTCAGAAGTGCCTAGCTGCCACTCCATTTATATGAGGCAAGAAGGC
+
@@@FFDDBFFFHHIIIIIIEHIGEFHIIIIIGIIID?FHIIIGGIGHGGIHEEHIIGEHGIIH@CCDEGEHHGEHHF>@DFCEEDC@CC>ACBDDBDCCB?
@27K
TATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCTACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJGIJJJJJJJJJJJJHHHHHFFFDDDDDDDDDDDDDDDDDDDDDDDDDDD>BDDD
@27L
CCTCCCTCCATCGCAGTCCATACCAGATAGCAGCTACCCCATGGACCACAGATTTCGCCGCCAGCTTTCTGAACCCTGTAACTCCTTTCCTCCTTTGCCG
+
CCCFFFFFHHHHHIFIHJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJIIJIJJJJIJJIHFFDDEEDDDDEDDDDDDDDEDEDDDDDDDDDDDDDDDDD
@27M
GCCCACACCTGGGAAAGGACCTAAAGGTGTATATCAAATCAGCAAACAAATCAAAGCTCATGATGGCAGTGTGTTCACACTTTGTCAGATGAGAAATGGG
+
CCCFFFFFHHHHHJJJJJIIJIJJJJJFHGHIJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJIJJJJIJEH?EEFFFFFFEEEEEEEDDDDDDDDDDDDD
@27N
CCTGTCTCCAGATCTCAGTAAGGTACGGAGTAACTGTCCAAAAGCCATGAAGAGATTAATGGCAGAGTGCCTCAAAAAGAAAAGAGATGAGAGACCACTCT
+
@@@DDDDDHBCC?B@HHGHGGGIHCFGGIICFGIIGCD?DEGGIDH@F@BCGCG>CGGE@FCEHH;ECDAHEEEAEHF9BEC>>;=?@CCCCC<?@C<>CC
@27O
CGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTAT
+
@C@FFFFDFHFHFGHIHIIIJIJIGHGIGIIDGHJGIJJJJIJIJIJJFIJJIIJABEDFFFDCBDDBB?BDCCDCDCDDDDDCDBDD>ACCCDDDC>CCD
@27P
GGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACAC
+
@@;DDDDB==CCCFEDEBHBBD<CEC@ACC<EFFE???:DEFIIEI@FFFFIBDFBB@AAFDF>7@EECEEEEDBDDD@BA@A=>@;AA@A;;@>AABA?
@27Q
CTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTAT
+
CCCFFFFFHHHHHJJJJJJJJJJJIJJJIJJJJJJJJJJJJFHIJJJIIIJHAEHHHFFFFFFEEEEDDDDDDDDDDDFDDDDDDDBDDDDDDDDDDDDDD
@27R
GCCAAAGCTTTCCCCCTCCTCTGATGATTAAACAGGAACCCAGAGATTTTGCATATGACTCAGAAGTGCCTAGTTGCCACTCCATTTATATGAGGCAAGA
+
;=<A1?@A+<?>A7?8)?CB+2?++2++?=?<*1:=:=35?;;=)9=7A9*.)88==9=>BBBB=A)7).7>;)77;>>;;>;(6>>@;5;;>;((,55;
@27S
GCGTGGTGCACATCATCCAGTCACGGGAGCCCTCCCTGAAGAATTCCAACCCCGACGAGATTGAAATCGACTTTGAGACCCTGAAGCCGTCCACACTGCGT
+
@@CDFFDDHHHHHJJJJJJJJJJJJJJIJJJJJJJJJJJJHJIJJJJJJIJJJJJHFCDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDD<
@27T
GCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGC
+
@CCFFFFFHHGHGIGIIIJJJJIIJGJGIJIGIHIIGIIJIJJJIJJJGHGBEIJGHIIJDHEHEHGGHHEEFFFFEEEEEDECDCDDDDCCDDDCCDDDD
@27U
CACATACCAACGGCGAGGATCACTTCAGCTCTGGCAGTTTTTGGTAGCTCTTCTGGATGACCCTTCAAATTCTCATTTTATTGCCTGGACTGGTCGAGGC
+
@@@DDADDBFFFF6CCDFD@98B@?0B***?<@C9C<=CFFE8;@A;=)==;;??;)).>AB@3;?BBBBA3>5;@ADADBA>BA>A?88:(8::935<>
@27V
GCCGGACGAGCCTGAGGACCCAGTGGAGGCCGTGTCCTCCCCGGCAGTGCCCCCTCCCACCAAGGTTGTGGCCCCACCCCCATCCCGCGAAAGCAACAGCG
+
=<=1+00?)8=CB5=A5?):=3?*:9*0);<(-'82==ABA=A:5=@;35;?===6==;278;28(48)282820(0-&&)9(31(2&)5&&)(3(+(89;
@27W
AATTCTCATTTTATTGCCTGGACTGGTCGAGGCATGGAATTTAAACTGATTGAGCCTGAAGAGGTGGCCCGACGTTGGGGCATTCAGAAAAACAG
+
CCCFFFFFHHHHHJJJJJIJJIJJJIHHIIJIGJJJIJJJJIJJJJJJIJJJJJJJJJJJJGIJCHHGHFFCDDDDDDDDDDDDDEDDDDDDDDD
@27X
ATGAACAGGCACCGTCCCCATGGGCCATGTGATCCGTGGCCAGAGGAAGGGCGCTGGGTCTGTGTTACCCCCGAACGTGAAGCACCGTAAAGGAGCTGCCC
+
--(88>811((((2.2(<2)2..938().23863)07=/(937736(.6('-'''',3.=((-(---5(3(')&&&)(+/2:;6/8-89526+((2226/8
@27Y
CTCCCACGTATGAGTCGGAGGAAGAGGACAAGTGCAAGCCTATGTCCTATGAGGAGAAGCGGCAGCTCAGCTTGGACATCAACAAGCTCCCCGGCGAGA
+
@@@DDDDDACFFC@EDDDF>FF?FHGEEGDGIBDGIEBGHGCHHEGGCFEHGFGHG?DAEFEE?>??CCCCAC>?@>CACAC?A??8::>?B<BB@@95
@27Z
CTTCCGGGGGCCTCACTGCTCCTAGAGCCCTCTTCGCTGACTGCCAATATGAAGGAGGTACCTCTGTTCAGGCTACGTCACTTCCCTTGTGGGAATGTCA
+
@@@DDDDDFHAAFGH@@GEGGGGCG@CE8CFEEGIIB4=ABDCEECCCCCDEDCC=?B(:@CCCC@5@>:@C38@A>28??@:@>9@@<44?@8>1:4>>
@280
CAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTAC
+
@CCFFFFFF8DFHIJJJIIJJJJIIJJIIJJGIJJIIJIGGIIIJIIJJGIIJIGHHFEEFFDDCE@CCDDDD;CCDDDDDDCCDCCDDDCDDDDDC9@BA
@281
CCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTC
+
CC@DFFFFHHHHHEHH1CFECFGHHIJ<FHIIIIDGIIIIJIJIGHJGEHGIJBFHGIIJGIIGHHHHFEEFC@EACCDDD>CACCDC>CCCDACABDDCD
@282
CTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTAT
+
CCCFFFFFHHHHHJJJJIJJJJJJJIJJJJJJJJJJJJJJJBHHHIIIJIJH?EHHHFFFFFFEEEEDDDDDDDDDDDEDDDDDDDDDDDDDDDDDDDDDC
@283
AGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACC
+
CCCFFFFFHHGHGIJJJIIEIIGGHIJJJJJJCFHIIJGCGGGIJJJIIIIGIJEHIJFHHEHGIHHFHFFDEECCDCEDEDCACDEDDCCBDBBBDDDDD
@284
CCGCCAGTGAGCGCGGAGACTGCTTCCACTTCGGGCGGGGGAGCCCCGGACCGAATCGGCTCTCTAGGCCGTGGAGCTTGCCGTCCCACCTCCGTCCAAAT
+
CCCFFFFFHHHHHJIIJJJJJJJJJJJJJJJJJIJJJDDDDDDDDDDDDDDDDDDDDDDDDDDDDEDDDDD;BDBDDDDDBDDDDDDDDD?ADBADDBDDC
@285
CCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGG
+
CCCFFFFFHHGHHJJJJJJJJJJJJJJJJJGHGJJIHJIJIJJJJJJIFIGIJIIIJJIJIIJGHHFDF@EFEEFEFEDDDDDDDDDDDDDDDCDCDDEDD
@286
GTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTAC
+
B@BDFFFFHGHHHJIGIGJJJJJGDFGIIJJJIJJJIJJJJJIFIGIIJJJJJIGIIJJJJHFHFFHHFFFFEEEEEEDDDDDDD@BDDDDDCDDDCCDED
@287
CTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGC
+
8??B?A;+;ADDDEEIEIIBB4CDEEAE9:C1*?DD9BB9BD<BD9;DDIDCE@8(=AC@C<'-5=@AA>63(55>79<=?<:>>3;>5>A4>>>>>183<
@288
CCTAGAGGGAAAGCGAGAGGGAGACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCTAAGCTGCAGCGC
+
CCCFFFFFHHHHHJJIJJJJJHIIJIJIJJIJJJJJJJJJJIJHEFFDFEDDDDDDDDDDDDDDDDDDDDDDDDDDDDEDDDDCCDEDDEDDDDDDDDDDD
@289
CTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTAT
+
<@@FFDFFFHHHHJJJIJJJJGJIJIJJJGGIIIIIJIIJJ7AAGGDHIJJG?AEHGCEDCFFCECCDDBDACDDDDDAC@>CCD@<ADDBBDDDAABACC
@28A
GTTTTATGGTCCTTTACTCACCTTGGTTGACCTTGTAGACCTGTGTGTAGATATTTCAAAAGGCTGTGTCTACTTGGAACGGATGCATTTCATTCACAGGG
+
@=;BDFADHFFHHIIGHIHIJJIGHIFDDGIIGGEFGHGDHII<F9??DBBHGGDFFGJIDH7C8B=8CEGEHHAGHAEHEFBDCEEEAECCCCDDCDCB?
@28B
CTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTGAGTTGCTA
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJGIIJJJIJIJJJJIJIGGHHHHFFFFEEDDDDDDDDDCD5@CDDEDDDE
@28C
CCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTAT
+
?@@ADDB?FFFDFEHIEGH@8FCAHIEFGIGIIEBFHGEFFHGGHBFBHCHHHHEBBDEACCACCCAD;>?CBBC?BBBA@?A@ACDCB@CBA??BCCCCC
@28D
CAAACAAGAGCCAGGAATGTATCGGGAAGGACCCACATACCAACGGCGAGGATCACTTCAGCTCTGGCAGTTTTTGGTAGCTCTTCTGGATGACCCTTCA
+
??@DBDBB>FHHFIIGBDFAFCABAFGAFIIIDHEGHH>DH@G@;AHABEC<CCACCCCCCCCCCACC<@3>:CBBB8ACC:@AAACCC@CC4:>A?CCA
@28E
GCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACC
+
@@@FFFFFGFHHHBHEIDHEGHIJBHHHGIJJIEDHCFHIIJGI?DDHHIIE2?@BBG>FAHIGBDCAEHHHFFFFFFECE>ADCCDDDDDDBDDBDDDB
@28F
GTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTAC
+
?=@=DBD?CCDC?DBGEG?DBFEF?FAG?AEE0@:@BFDDADEBGHGEF>7@8@;@;=7=D)=;=?CHE>C@6A6;6@<??CB79(5<C<<B91?CC4@D:
@28G
CCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAAC
+
CCCFFFFFHHHHHJJJIJJJJJJJJJJIJJJJJJIJJJJIJJJJJJJJJIJJIJJIJJIJIJJJIHHHFFFFFFEEEEEEDDDDDDDDDDDDBDDDDCDD
@28H
GGAAGAGAAAGTGCCTGTGAGGCCCAAGGACCCTGAGGGGGTTCCTCCTCTCCTGGTCTCTCAACAGGCAAAACGGGAGGAGGAGCGCAGCCCAGCTGCCC
+
??=BB;BDHHFHF@DE?<:?A??CFHIBFEHEEDHIGCB@@@B@AHGHAEEHFHEE;;BC>CCCCCBBBBBBCBB?;5<@BB@028<959>BBABB:>A?B
@28I
GCCTAGCCAACCCTGGAAGCGGGCAGATCCAGCTGTGGCAATTCCTCCTGGAGCTGCTCTCCGACAGCGCCAACGCCAGCTGTATCACCTGGGAGGGGACC
+
CCCFFFFFHHHHGJJJJIJJJJIIJJJJJJJJIJJJJJJJJIJJJIJJJJGHHFHFFFFFFEDCDDBDBDDDDDDDDDDDDDCCDDDDDDCDDDDDBD<BB
@28J
TAATGACTTTACCCTTCCTGATGTGAACCTTATTGGGGAGCATTCTGATGCAGCAGAGCTTGGAAGGATGCTTCAGCTCATCTTAGGCTGTGCTGTGAACT
+
CCCFFFFFGHHHHJJJJIJJJJJJJJJJJJJIIJJJJJIIIJJJJJJJJJIJJIJJJJJJJJJJIJJHHHHGHFFFFFFEEEDEEEDDCBACDDDCCDEDD
@28K
TGAACACAACACCATGGTTGGCAGTGCGGCCAGCCAAAGCTTTCCCCCTCCTCTGATGATTAAACAGGAACCCAGAGATTTTGCATATGACTCAGAAGTGC
+
C@@FFFFFHHHDHJIIJEHIJJHIHFIJJE@GGIIIGJIJIGIJJJJJJJGGGEE?BDBCEFFCEDEDB?=@DBBDDDDDDDDDEECDDCDDDDDDDC4@A
@28L
ATGCAGGCGCTGCCCATGGGAGCCCTGCCCCAGGGGCCCATGCAGAATGCCACCAAGTATGGCAACATGACAGAGGACCATGTGATGCACCTGCTCCAGA
+
@@?DDBDDDHHHHJJIHGIJGE@DH>FHGJJEAEHIEIJGGGIG@GG>AHHFGEBBB?CCCEAEDBDD@ACAA>CD@AAA>@:>>@@A@ACCDB:@C@AA
@28M
TATTGATGACTCCAATGAGCATATGCTTACTGTATGGGACTGGCAGAGGAAAGCAAAAGGAGCAGAAATAAAGACAACAAATGAAGTTGTTTTGGCTGTGG
+
@@@FDBDDFDHAAGHGG+CHEGGHHIB<FFHECHEBGGC?BDGGHHAGCGGGI;DGEHII@GCFDGIGGIFHCHEDF;BBB@CC>;>@ACBD?BDCAB<?C
@28N
TTTTGTGATGAGAACAGGAAAGCCTACAAATTTATTAAGGGAAGAAGAATTTGGTGTTGATGATTCTTATTCTGAACAAGGAGCACAAGACAGTCCGACTC
+
@C@DD;DDFFF>A:CEFBAE@FHIIGEIEHGGHGCDGCHGH<BFFHBHHIIIHD0BFGE>AC7==;F@GCH>EHCEFGHFF@DCCBCB?C?CA>CCCCBBC
@28O
CTTGACCTGTCCAGGCCCTGGAAGAGTGGCCAAGATTGGAGACTTCGGGATGGCCCGAGACATCTACAGGGCGAGCTACTATAGAAAGGGAGGCTGTGCC
+
@@;BBD?DBBFAF?AF?CF;3EHCH321:??DH@H@:?@?B@?9DHCFEA'5;7@G8B8,=7666>3>5;;?28855A::C>>>CA:+228<>B<82>AC
@28P
AGCATTCTTAAAGATGAAAAGAAAACCCTTGAAGACATGTTGAAAATACATACTCCTGTTAGCCAAGAAGAAAGATTGATTTTCTTAGACTCCATTAAGTC
+
@@CFFFFFGGHFHHGIJJJIJJJJJIIJJIJJJJJJIIIIGJIJJJJIJJJJJGIIJFJIJICEHIIIIGEGGHHHHHGHFFFFFFFEEECEEDDEDDDDE
@28Q
CACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCC
+
@@CFFFFFHGHGDIGGIIJJJIIIJIIGGHIIIJIIJGIIIGIGIIEHHGIIJJJJIJIJIJJGGHJJHGHHHHFFDFFAECEDBDDBDDBDDDDDDDDD
@28R
GATCCGCCGCCTCTCCCCGGCTGAGAGAGCTCAGGGACCCAGGCCGCACCAGGAGAACAACCACCAGGAGTCCTACCCTCTGTCAGTGTCTCCCATGG
+
@@@DFFFFFHHDHIIJIJGAHIIGHHIJJIJJJJJEIIJIJIGFHFDDDDBDBDDDDCDDDDBDDDDBBD<?@ACDDDDDCC:ACC@A@C>CCDCCDC
@28S
CTTAATACTGCTTTTTAGCCTTGCTATACATCCTGACAAAATTAGGATTGCAACTGGACAGATAGCTGGCGTGGATAAAGATGGAAGGGTGAGTGGCAT
+
CCCFFFFFHHFHHJIJIIIJJJJJJGIIIJJJJJJGIIIGHIHHGJIJIJGIJJJJJJJJIIIGGIIJIJJAEHDEEFFFAEEEEDDDD2<ABCCBDCD
@28T
CCTTATTCAAACATCAACAACAGGGACCAGATAATTTTTATGGTGGGACGAGGATACCTGTCTCCAGATCTCAGTAAGGTACGGAGTAACTGTCCAAAAGC
+
CCCFFFFFHHHHHJJJJJIIJJJJIIJJJJJIJJJJJJJJJJJHIJIIIJJJJIJIIHHHHHFFFFDDFEEEEECEDDDCCDDD?B?ACDDDACDCDDDDD
@28U
GGCTCATCCCAGCAGAACAGAAGGCTGTATGTTTGAAAAGGGCCCCAGGCAGTTTTATGATGACACCTGTGTTGTCCCAGAAAAATTCGATGGAGACATC
+
<@@FDDFFH@BBFHFIGGGGCHA@FFD@EGG@F@FHIGI?DECHI@AHIGECHIICGIG;7@EEAA?>C);@>B?CECACCCCCC=AC@@3>?C?A@C@:
@28V
GTTATTGATGACTCCAATGAGCATATGCTTACTGTATGGGACTGGCAGAGGAAAGCAAAAGGAGCAGAAATAAAGACAACAAATGAAGTTGTTTTGGCTGG
+
@?@A;DDD4C?ADGFF>BFEHFHGE9FBHEEFCIA9CFGF>C3CGDCC1BD>@;B?F@FFFFCE(6@;=)7?E>A=;>B=@?@>A>5>(-;(5<??B5:?'
@28W
CACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGG
+
CCCFFFFFHHHHHJJJJJIJJJJJJGIIJJJJJJJJJJJJIIJGIIIJJJJJJIJIIJJJJJIIIJIIGHGHEFFFFEDEEDDDDDDDDDDDDDDDDDDDD
@28X
CTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCC
+
B@CFFFFFHHHHHJJJJIIJIGJIIIJIIJJIJIIGIJIJJIICHIHJJJJIJIJCEHIFHHGHGDFFFFEEEEDDDDDDDDDDDCDCCDDDDDDDDDD
@28Y
CTTGAATCGGGCTGGTTTCCAAACAGAGGATTTTAGTCTATATGCTTGTGCTTCTCCAAAAACACCCATCCAGGCAGGGGGATATGGTGCGTTTCCTGTCC
+
@=?DADDDFAHHAGGFGBCBHEHGIGEEGEGGIIIGFHIIDICHFHBFGGEIHAGGIIIIIIGGHFFED@E>CC?ABBBBBBB<CCCAAC<8?>CCCCCCC
@28Z
CAGCAGAACAGAAGGCTGTATGTTTGAAAAGGGCCCCAGGCAGTTTTATGATGACACCTGTGTTGTCCCAGAAAAATTCGATGGAGACATCAAACAAGAGC
+
CCCFFFFFGHHHHFHIJJIIGIIIJJIJJIJJJIJJJIJGIJJHIIIJJJIIIJJEGIJIIGJJIFGHHHFFFFFEEEDDDDEDDDDDDDDDDDDDDCDBC
@290
GCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGC
+
C@@FFFFFGFHGHGIIJIIJJJJIIIJJJJJIFGHGIHJJJIGJJIJJIJJJJIIJGBHHJIGIJJJHHFDDEEEDDEDEDECCCDDCDDCDDDDCCDD
@291
AGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGGGTTTATGGGCAGG
+
@<@FFF?;?FDHHGCFBDIHFHGIGIIIGGGGG>G?D?>?FEHHDFHGIEB=F=@=@CGGC7>EDB;ABCA=@:>?B>:>C@CCBA(0&0<A:@CB<A3<
@292
CTTAAATCAGAACAGGACTTGATTAGAGACCAAGGATTTCGTGGTGATGGAGGATCAACCACAGGTTTGTCTGCTACCCCCCCTGCCTCATTACCTGGCTC
+
CCCFFFFFHGHGHJJFJIIJIHIIJJJJJJJJJJJIJJJJJGGGDHIJJIIIJIJIJJJIJJJIIEHHHFFFFFFFEEEDDDDBDDDDDCDDDDDCCDB<C
@293
AAAAAGAAAAGGGTACACTTGAACAAGAAGTTCAAGAATTACAACTTAAAACAGAATTGTTAGAAAAACAGATGAAGGAAAAAGAGAATGATCTTCAAGA
+
@@;DBDBB?D?F72AABGCHIIGGH>BEFHF9?FGGEGDGGHHCGC@BFFDBBDHEECAFHGGCGGIIB6@;=AAE:?B@CCCBB;CA>@:@A@CC>5>A
@294
CCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATG
+
@@CFDFFDDDHFDHGIG<AGGGDEGGHIGAFEGHEGDGBDDGHEGGGHIEGEGFGGABCGE@AHEFEFFF?>CCECDDC8;??BBDDDDBBB@BCCCCCDC
@295
GACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTG
+
B@CFFFBDHHHGHJIJJIJIJIJJIIGIJIGHGIIIIJJJJGIIJIIIGHIJJJIIJJHHHHHHFFFFFFEEEEDDCCDDDDDBDDDDDCCACDBDDDDDB
@296
CCCTGATTTATGACGACGGCCTCTCAGAGAAAGAGACACCGCTGGTGGAATGAAATAATGAACCCATCTCTCTAGTCCTTACTTCCAAATGGATTGAAAA
+
====1@A4A4>,?A7<)))))))1174=3)0*079>A9>;:';6>>7A(.7)).777)7((((('(-5((,((55,,(5(((,3((+(+8(3(48(3:;8
@297
GTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACT
+
@@@DFEFFDBHDHGIIIIIJHFHGCHICDFEGEGGHGGGGICHIJIIIHIJIGGGIDG3=@CHGGICHHFACDBDDCC@CC>@CEDDDCDCDCDDDDBDBB
@298
CTCAATTCGACTGCCCCGGGCACTCCCTGTGGAGGCCTTGAGGGTCCTGCACCTCCATTTGTGACAGCATCTAATGTGAAGACCATTCTGCCCTCTAAGGC
+
@@@DD?DDFFFAFFB9F?@:GEGE?9BBB?B9??F@FFC>=FF?;8=@EEE;A>>C;?777.3>666;?;A55@3((5;;55:<<@@;:AB@<:83@A3(>
@299
CTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTC
+
@@@DD?DBHHBD?GIGGII::D@FGCHGHIIIIEEHIIBEAHCFHIIGHGGGAAEEFDEDE@DB;@CCCCBB>@CCCCB?<?BBCCCBBBCCC@CCBBB>C
@29A
AAGGCATTTCACACAGTCTGTATGGCCCAGGTAGTGTCGCTGAGTTCTCTCCTCATAATTAAATAGTACTACTACTGATGCAATGAAATAAACTATTTCCC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJEGIHIIJJJJJJJIJJJJJJJJJJJJJJJJJJJJJGIJJJJJHHHHHHHFFFFFFEECEEEDDDDEEEED
@29B
TTTTGAGTCATGCTACTCGAATTACATTTGAATCATATTATTTGAAGTATATTTAGGTGCAATTATGAAAACTAAGGATTATGGCTTCTTAGAAGGCAGC
+
<@@DDDDDHFFHDIIIIGHGIGGCFDHFCAHFGB@HGGHBDHIE?DDHDGGHCGGGC??FGIIIIIIIII@;CD@FG>DEH:=AEEHCED:;36>AAAB@
@29C
AGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACA
+
?@@DDEFDDBFDHIIG@FHGIIIEEHEH@EGIEECF>G>BGEDDFH;FCHIGIIEHGECG@GGG@DCEE@AAEDC<7ACEDBBBDDDD9<CCA>@CCCC@
@29D
GTCAGCGAGGACACCTGCCCACTGAATGTTCATTCTTATGACCCCCAAGGAGAAGGCAGGGTGGATCCTGATCTGTCCAAGCCTAAAAACCTTGCTCCTTT
+
@;?BDDDDHFAHD@FEHGBGHEAEGGCGFG:BGGDFGC9<D9BDFAAADG@FC>DH=;AHE;?B?:@=;A@C:;>A;@C:A<8>@CCCA<<?CC>CCCCCC
@29E
TTATAGATATTGCACGACAGACTGCACAGGGCATGGATTACTTACACGCCAAGTCAATCATCCACAGAGACCTCAAGAGTAATAATATATTTCTTCATGA
+
CC@FFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJIJJJJJJJJHHHHHFFFFDEEEEECDACDEFDEEEDFEFEEDDEEDD
@29F
CTGTGATTCCTGAATCTACAATAATGAGAACTCTACATAGTGGAGAAATAACCAGTCATGAGCAGGGCTTCTCTGTGGAACTGGAAAGTGAAATTTCAACC
+
@@@DDDEFFFDHHHIIJJGIJIJJICHHIJIJIIIIJGGEBFFHCGGHCHIHHHHIIIIIGGJIGDGGIIGGIIJCEEHGEGDCFCDE;@@CECDDDEDD;
@29G
GCAGTGTGTTCACACTTTGTCAGATGAGAAATGGGATGTTATTAACTGGAGGAGGGAAAGACAGAAAAATAATTCTGTGGGATCATGATCTGAATCCTGA
+
B@@FDFDDADHFFJJJIJJEIJJJFJHGGIIGIIIGHIGHIIIJJJJJIEGIFGGIGJJIJJJIIJIHHHHHHFFFFBDEDDEDDDDDCDDDDDDDDDDD
@29H
CCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTAT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJIIHIJJJJJGGJJJJJIJHHHHHFFFFEEDEEEDDCDDDDCDDDDDDDDDDD
@29I
TCAAAGTGCTCGGTGCTTACGAGGAAGATAACGGTGCGTTGGGGTGAGGGCCTCACTTCATCGGGCGACTTGAACCGCGTCCGCCAGCGGCAGACGTACAT
+
78((2.)29=@((2-(.)325(:/;>?(63>)(:6>3(;(-;'''5(.6(9(69=3=1((--(3,,)&&)(822(())0)&&)&25)60&&5:(+&2((2(
@29J
CTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTAT
+
??;D?DDD>DFH?1C@BCBAG@B@CC?;D7?FF<DFB>DAG<AFFGHIGHCH.=ACEBD;B3@CC6>A9?CCC(-:,:((53:59888<9?8(8<@?B?C:
@29K
CCTACACCTCAGCAGTTACAAGCCTTCAAAAATGAAGTAGGAGTACTCAGGAAAACACGACATGTGAATATCCTACTCTTCATGGGCTATTCCACAAAGCC
+
<1::BDDDFFFD<F>FGF@HI3?GGFFF9FEFAGFCICF@F@?DFEDD<<;?B9BBFEBA;@8=@AE>A;77=?B)7?B>;6>A@9??@AA;55>:9<>9?
@29L
CTCTGATGGACAGCAGATACTTGTGCCCAGCAATCAGGTGGTCGTACAAACTGCATCAGGAGATATGCAAACATATCAGATCCGAACTACACCTTCAGCT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJIJJJJJJJJDGIIJJJJJJIJJJJJJJJJIHIIJIIJJHHHHHFFFFFFFDEEEDDDDDDDDDDDDDDDDD
@29M
CTGAAGCCGTCCACACTGCGTGAGCTGGAGCGCTATGTCACCTCCTGTTTGCGGAAGAAAAGGAAACCTCAAGCTGAGAAAGTTGATGTGATTGCCGGCTC
+
C@CFFBDFHHFHFIIIGIJEGGIHIGIGEGIIJJIJGBFGIIGJJIJIGIIIIHEDDCECEEDDDDCDCDCCDCCDCBCC?CACCCCC>>C@DDCD<>B9<
@29N
GGAATTTTTGGGAAATATGAAAAGCCAAAATTTGTGCAGAGTTTAGCATTCTTGGGGAATGGAGATGTTCTTACTGGAGACTCAGGTGGAGTCATGCTTAT
+
8;?BBADD?ADDAC32:<C?:AEE3CCDE8CEECDDDDC*0?@DE?BDDDE9BDD;@<AA;=3=A37A77A==CCA>A27;A;@A>-5;;=>>A;>A>>>:
@29O
CCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJGIJJJIJJJJJJIJIJHHHHHFFFFFEDDEDDDDDDDDDDDDDDDDD
@29P
ACTCACTCTTGCCCAGCTGGTCCAGAAGCGACTCATGGCCTTGGAAGAGGAGGAAGATGCAGAGGCGCCTCCAAGTTTCAGTGGCGCTCAGTTGGACTCA
+
C@CFFFFFHGHHHJJJIIIIHGIIGGJIJJJJIIIGGGIGHIGGGGH;FG=FACHIIJFIDHHEHFDDBBDDDDCDDEEEDDDD@B><BDCCCCDCDCDD
@29Q
AAGAACCCCACAGTCCATGTTCAGAAATCGGCTCTGCCTGCAGTCAAGAACAGCCCTTTAAATTCAGCTATGGAGAAAAGTGCCTGTACAATGTCAGTGCC
+
@@;DDDDDFFFF;<<AGIEAFCDBEB?FADA>1CF?:BFAA>DGIIAFFFIIII;CFCFFI7C47=;>A)=?BDB@A>@@(6-;5>;5(;:>5@@(5,:@A
@29R
GGAGTTTGTCTGCTGAATGAACCCCAATACATTATCCTGGAACTGATGGAGGGAGGAGACCTTCTTACTTATTTGCGTAAAGCCCGGATGGCAACGTTTT
+
?@@DBDBDHHHDDGGGBHIIIGHIIGIGJAGBCEF9CGHHIIGDFI<BGBFGBGEH?@DHIG;=CAHHDFDEFFEC<3=?BC@A(8;?-5?<CC?B2<?@
@29S
GGGAGACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTT
+
@@@BDDDDDADFHEEHGGIIJHI>DEDFFBDHIHIHHIJJJDGCGBBADD?BBBDDDCCDEDDDDDDD>CCCDD?CCCCCCBD@@B?BBDBABDDC>AADD
@29T
GTTGGAACAGTTACTTACACACTGTGGAAAAAGGCAAATCTATGACAACAATGGGGAGCGTTTTGAATTTTGCACCCGGGAGCCGGTTGAAACCACCAGCT
+
((-((<).():4.=))).)))())<)):)))(:=(((:)<?))))0=)<?(=))(((--''('8(7);))6=>?(:(,9'''0(0&&&&((((++(2:(8(
@29U
CCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJIJIJJJIJJIJJJJJJGIJJJJHHJIJJJJJEGHJJIJJJJHHHFFFFFCCDDDDDDDDDCDDDDDDDDDDDDD
@29V
CAAACATCAACAACAGGGACCAGATAATTTTTATGGTGGGACGAGGATACCTGTCTCCAGATCTCAGTAAGGTACGGAGTAACTGTCCAAAAGCCATGA
+
?+8AB:BDFDFFFB=G=BDEF?E@<EGEIIIIEBDGGEE6BFAB;:8@=FFDECEE=?;=AE@DDDDDDC(..;@?B=25:AB@@::ABBBBABBB::3
@29W
CAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTC
+
@@<DDDDDDHFHHJIIGGIJJHIIJIGAGGFCBCGHFD@DDDGGIFIJII3DGCGCHI=FH>GGHI=EE;BDECDEDACCEDDDDDCC?ACCCBACCADAB
@29X
CTGGTCCAGAAGCGACTCATGGCCTTGGAAGAGGAGGAAGATGCAGAGGCGCCTCCAAGTTTCAGTGGCGCTCAGTTGGACTCAAGTCCTTCTGGTTCTGT
+
@@@FDDDBF<FFDFBGEHDFHHDGGHEF@GB??GHGIIG@BFGHGGIIIIGBEB<?CC>6>>CFA6@CB@?BB?C>@@CCC>?CAA::@AC:>:A>>CCA4
@29Y
CACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCA
+
@@@DFDDDDHHHHIIIGIECGIJBEGG<HGH@D@B<>C@FFF?FHA@F<DHFHAFAB@DAHA=AC:7@>@@@6A>==ACCBD59<CD@A@>CCCC@:ACC
@29Z
AATAAATGAACTGAATATAAAATTGCAAGATACTAACTCTCAAAAGGAAAAACTCAAGGAAGAACTAGGACTAATTTTAGAAGAAAAGTGTGCTCTAC
+
CCCFFFFFHHHHHJJJJJJJJJIIJIJJJJJJJJJJJJJJJJJJJIIJJJJJJJJJJIJJJGJJHJJGGIJJJJJHHHHHHFFFFFEECEDCEDDDDD
@2A0
GTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACT
+
C@@FFFFFGHHGHHGIJFIGIGHGJIJJJFIIJIIIIIIJIGIIJIJIHJIJJIJJJJIJJIJJJJJIHHHHFFFFEEEDEEDDEDDCCDDDDDDDDBBB@
@2A1
ATGTTAATCAGCAAATTCATCCAGCATTACTTTGTGCTTTGCTTTTTTTAATGCTTGTTATCCCTTTAACGAATCAAACGGCTGAAGCTCATTTTGGTGGG
+
(((-().<@?@16@@?@8@)3))))3))):):)..)))):):;??))((.)))))9).)):))):)))))-((.7=))(',,''(,:(((7;22(5)+28:
@2A2
GTGCCTCTTTCTCACTTTGATGAGAGCATGGCCTACATGCCGGAAGGGGGCTGCTGCAACCCCCACCCCTACAACGAAGGCTACGTGTATTAACA
+
@@@FFDDFHGHHGIIIIJJGJJIGIIJJIJIIJJIJJGIGIIJIJIJJJIGFHHFFDFFFEDDDDDDDDDDDDDCDDDDDBDDCB?C3<CDEEDD
@2A3
CTCTCCTGGTCTCTCAACAGGCAAAACGGGAGGAGGAGCGCAGCCCAGCTGCCCCACCACCTCTGCCTACCACCTCCTCTGGCAAGGCTGCAAAGAAACCC
+
@@@BDDDDFDDDBEGHIAHIIGIHDDEHEHHGGCDB@BDHHGAGHIGGCHFEBBDBCCCBB@BCC>AA:?<@@?BBBC<CCCCAC82?4<89@CCC?CAB?
@2A4
AGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCC
+
@CCFFFFFBHBFFGIGIGIFFGHHJDHIJ<CGFGEIJIGCHIEGCGHIIGHEHECFBGHJJJIC@@CGHHEEEDDAAACBCCDDDDDDDDDDDDDDBDDDC
@2A5
GAAACAGCACTCATAGTAGCACAGCTGCAGACTTACTACAAGCCAAACAACAGATCCTCACTCATCAACAGCAGCTTGAAGAACAAGACCACTTATTAGA
+
CCCFFFFDHHGGHIJJGHGEIJJJJJJIJJIIJJJJIJJJIJJIJJJJIJIJJIIIIEIJJIJJJIJJIJHGHHHFFFFFDDDCEDDDDDDDDDDDEFEC
@2A6
GTCGAGGCATGGAATTTAAACTGATTGAGCCTGAAGAGGTGGCCCGACGTTGGGGCATTCAGAAAAACAGGCCAGCTATGAACTATGATAAACTTAGCCGT
+
@:?BBDDDADBFDFEEGGIB99<3CDBAACC;;FF9*:B08?FF=AFFB;@C=AB6<@>BACBABBB><@?BBB9<A@:44>>:A::ABBBB@BB:A:>05
@2A7
CAGCGTAAAGCCCAGAGACCTCCTGCTCCTGAGGCACCCAAGGAGATCCCACCAGAAGCTGTGAAGGAGTATGTTGACATCATGGAATGGCTGGTGGGGAC
+
CCCFFFFFHHHHHJIJJIJJJJJJJJIJJIIJIJJJJJJJJJIJJJJJJJJJJJJJJJIHHCHHDFFFF@CEDEDEDDDDDDCDDDDDDDDDDD<CDDDBB
@2A8
CAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCT
+
C@@FFFFFFHGFHJJJJJJFIJJJJJJBHGIJJJJJJIIJJJIEHEGIEIJFHIAHIGIHFFDFFEEEDEDCDDDDDDDCCCDDCCCCCDDDDDCDCDD
@2A9
CCACACCTGGGAAAGGACCTAAAGGTGTATATCAAATCAGCAAACAAATCAAAGCTCATGATGGCAGTGTGTTCACACTTTGTCAGATGAGAAATGGGATG
+
CCCFFFFFHHHHHJJJJJJJJJJJJDFEHIJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJIJEH@EHHHHGFFFFFEEEEEEEDDDDDDDDDDDDD
@2AA
GGAGAATAGCAGATGTGCAGCACATTAAGAGGAGAGACATCGTGCTGAAGCGAGAACTGGGGGAGGGAGCCTTTGGAAAGGCCTTCCTGGCCGAGTGCTAC
+
;;??DDD+:ADD?EE::,:C@FC>??EEC@AFB@ED>BD<DDDB7DDBD?3?B<8'.873.'5=@?68,88A::,5:>A<8(2::>A>:9<?;>;<>ADA3
@2AB
AAAAAAGAGAAAAACGTCAAGCAGTAAACATGATGTGTCAGCACACCATGATTTGAATATTGATCAATCACAGTGTAATGAAATGTACATAAATAGTTCTC
+
CCCFFFFFHHHHHJJJIIJJJJJJIJJIJJJJIJIHIJJJJJJJJJJIJJIJJIJJJIIJJIJIJJHHHHGHFEFCEFFEEEEDEDDDEDDDDDEDCDEED
@2AC
CCAAAATTTGTGCAGTGTTTAGCATTCTTGGGGAATGGAGATGTTCTTACTGGAGACTCAGGTGGAGTCATGCTTATATGGAGCAAAACTACTGTAGAGCC
+
CCCFFFFFHHHHHJJHHHIJJJJJJJJJJJJJJIIGJJIJJJJIIJJJJJJJJJJJJJJJJJFGIIJ@EHGJHHHGHHHFFFFFDEEEEDCCDDCFDEDCD
@2AD
AGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGC
+
CCCFFFFFHHHGHJJJJJJJJJJJJJJJJIJJJJJIJJJJJJJJJJJJJJJJJJIJJJJJJHHHHHFFDFFFEEDEEEDDDDDDCDDDDDDDDDDDDDDD
@2AE
GTAGGATGCCTGGATTTTTCAAAAGCAGATTCAGGTGTTCATTTATGTGTTATTGATGACTCCAATGAGCATATGCTTACTGTATGGGACTGGCAGAGGA
+
@B@FFEDFHHHHHIJIJIJJJIIIJJJJGIIGGHJ?EGHJJJJJIJIIIGIJJJJIJJJIJJJJJJJJJJJJJJJJJJJJHHHEHHGFFFFDDDEDDDDD
@2AF
ATGTATATGCATTTGGAATTGTTATGTATGAATTGATGACTGGACAGTTACCTTATTGAAACATCAACAACAGGGACCAGATAATTTTTATGGTCGGACGG
+
(555;>91)))26))<>41))3));;);282)248=););)67:1=;<1)333<8>:)<<<)79:1))731=(:;5=3(6:).6.6;;=.8=73(',357&
@2AG
TTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGC
+
@@@FDFFFDDHHHJJHGEGJIGGIJFHFGIIIJJEHGIGCGGDFHIEHGGIJJJGCADGHEHHEHFHHFFFFDFE>CECCDDDDDDCBADCCCDBDDB?AD
@2AH
GACAGGCCCAACTTTGCCATCATTTTGGAGAGGATTGAATACTGCACCCAGGACCCGGATGTAATCAACACCGCTTTGCCGATAGAATATGGTCCACTTGT
+
11+B;D1B?DD:C9??A<CF;<2<C@E6E;BEC):C?BDD<DDED@<B;DD==B25@>A<A;@?>>D3(61>39,8<>3,3'0&&::(4>>(::AA:(4>(
@2AI
GTTACCTTATTCAAACATCAACAACAGGGACCAGATAATTTTTATGGTGGGACGAGGATACCTGTCTCCAGATCTCAGTAAGGTACGGAGTAACTGTCCA
+
=@@??BD>AA<<A?:<??AH@@<F3:A;G;11??C?9??FB<?BBF9*086(.-4AE@)=E;7..;BB?;636.>;5;@;5;>5(528?B53@>::+4:4
@2AJ
AGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCCCTACACAGCCGACTAGTTATG
+
=<=<A>AAA?>+=AAC4<?++?CAA?AA;=?AA*::<):==00?=9A9>7=BBB>A>ABAABABAA7==))53;3;.;(6>==?=?====66;58;;?:8
@2AK
CCAAATCCGTGATCTGCCACACTGCTTATAAAGAAGGACAGAAGAGAGCGGTCAGCTAGCAGTGATTAAGTACGAGGGGAGGGCGACCCATAAACAAGCTG
+
;3(8;)2.-((2).))))))(())))2)))))).()2..)(..)0..(.('-5;).6)8)86....:9))..;((,'',3'&)))55)&(((+(5/((((+
@2AL
CAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCAC
+
@@@FFFFFFFHHFGIJIJGGIJIGIIIIGEFIJIIJIIIGAH:?DFGGGIJIIGIGIFG@GEEHHHHFCFCFFFDECCCCD?>>@CBDDDDBDBDDCBDCD
@2AM
GATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCC
+
@CCFFFFFHHHHHJJJJJJIJJJIJJJJJJJJJJIJJIJJJJJJJJJJJJIJJJJJJJJGIGHHHHGFFFFFFFEDEDECDDCDCDDDDDDDDDDABDDDD
@2AN
CTTCAGAAGAGAAATCATAAAGACAGCCAGTTCGAAACTGATATAGTACAACGAATGGAACAAGAAACACAAAGAAAGTTAGAACAACTCCGGGCAGAGCT
+
@C@FFFABFBFHHIEHBHCHCFFGIGIGGIH@GGGHIJIB:BFHAD9BDBFGIIIGEECCHG@GADHH?=EF;BDD@ACCDCCCC??;@CCBDDBBBBBC>
@2AO
GCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACC
+
@@@DDDDDHD?DB@F@DHCHHIIIBHAGBGCGHBC?9?FBEDGCHIIIGGGF8BFA@;@@DD@G;AAE===?;AA@A6@CDC@@ACACAC<BD@BCDC>8
@2AP
TTATGTGTTATTGATGACTCCAATGAGCATATGCTTACTGTATGGGACTGGCAGAGGAAAGCAAAAGGAGCAGAAATAAAGACAACAAATGAAGTTGTTTT
+
@@CFFDDDHGHHHGIJIJJIIJJJJIJIJJJJJJIJIIJJDHIIJJGIGIJDDGHGIIIIJJJIJJJIEHDHHFFHFFFFEFEEEDDDDDDADDCCCCBDC
@2AQ
GGAAGGATTTCCAGAGGGAGGCCGAGCTGCTCACCAACCTGCAGCATGAGCACATTGTCAAGGTCTATGGAGTGTGCGGCGATGGGGACCCCCTCATCATG
+
@@8DDDAA?CFBDEFEFHGEABGII0@DGHGGD<?DHHIFHIGGIIIGEIIGI>AEA3==7@)7?>B>@C@A@55>;>8=>9>@>BB<BB?BBBB?@ACDC
@2AR
CTCAGGAGGAGTCATGCTTATATGGAGCAAAACTACTGTAGAGCCCACACCTGGGAAAGGACCTAAAGGAGTATATCAAATCAGCAAACAAATCAAAGCTC
+
;3;(=@)8>5=><4.4:8.9=889)).9?7<<.3.;<>6>?1>?<?5-;-<9=;93=>5>?7:?;7>?<(..89==3=>81=1;37;><<<8:;;:<0;5+
@2AS
GCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATAC
+
?7+:;ADB?DF?FFIEB;;ACABC<<F?CGCEGEFAFEEGI>9?F9B>DCF;@;;@@@AA=;>BDD=?>@C>>A@?;6,3>A@<ABBBBA33>A@ABBE>A
@2AT
TTTGGAAATTTCAAAGCTAAAAGATTTACAGCAGTCTCTTGTAAATTCAAAGTCAGAAGAAATGACTCTTCAAATCAATGAACTTCAAAAAGAAATTGAA
+
CCCFFFFFHHHHHJJJIJJJJJJIJJJJJJJIJJJJJJJJJJJJJJJJJJJJGHJIJJJJJJIIIJJIJJJJJIJJJJJIJJHHHHHHFFFFDEDDEDDD
@2AU
CACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCC
+
CCCFFFFFHGHHHJJJIJJJJJJJJJIIJJJJJJIJJJJJJJJJJJJJIJJIJJJJJJJJJJJIJJJIHHHHHHFFFFFEEEEEDDDDDDDDDDDDDBDD
@2AV
CGGATAATGACTCAGTGCTGGCAACATCAGCCTGAAGACAGGCCCAACTTTGCCATCATTTTGGAGAGGATTGAATACTGCACCCAGGACCCGGATGTAAT
+
@@@BDFFFHHFHHGIAE>FEFFIIIGIIE@FHACFFHGHGGG=DFFHGBDHHICCGGCFGDHII@E>AECEF>>@DFEEECECCBBBCCBBBBBB>@CDDE
@2AW
CTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTAT
+
C@CFFDFDHGHHGJJIIJJJCEGIJJIGICGAFHIGIEEGEGBEGGGEGGGE=AEEHFFFFFEDEEEDDBACCCCDCCCDDDDCDDBDDD?A@DBDDDCCD
@2AX
TTTCAAAAGGCTGTGTCTACTTGGAACGGATGCATTTCATTCACAGGGATCTGGCAGCTAGAAATTGCCTTGTTTCCGTGAAAGACTATACCAGTCCACGG
+
@@@DDD?DB=CFFFGHGGHAHHCF<FDGGEHHAHCDDCGII<?FBDF<BFHIGID=BFGA@;8@@D@=7AAEHHEC7?B=ACCC>?CCCCCC@CCCCC:<>
@2AY
AGACCACCCAGGCATATGGGAAACAAAGCTATGGAACCTATGGACAGACCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGAGC
+
:=<A=@3A8+7;8=CB<BB++<?++51?3*?ABA?>*0)7AB>4>*0*0=A5AA=77).=>;;7)7>>=A9<(;5>>>>(.,;;3;>3;=??>:==95;((
@2AZ
CTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTAT
+
@<?AADDD;FHHHGBE==GCDHEDBG;BDCAEFGHIFBG<@@<=7=D=CAGE==>CHD@?D7;>>6;?;=-;;@3@CCDA@AC>A?@BBBB<@?<42?C>A
@2B0
TGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTT
+
8=??A?ABBBD?<ECGII?CFD;<9FB@<EF;??@BFGB?D**?FA>D?B<?DBFAF;=)7=CE;==7AEAAB@;777@;@35;58;235@@(44:A4@B:
@2B1
AGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCAC
+
BBCDFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJIJJJHHFFFDDEEEDDCDDEDDDDDDDDDDDDDDDDDDDDDDDDDDDDDED
@2B2
CTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTAT
+
CCCFFFFFGHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJAGIJJJJJJJHAEFHHFFFFFFEEEEDDDDDDDDDDDEDDDDDDDDDDDDDDDDDDDDDD
@2B3
CCTGAGAGCACTCCCAGTTTGGATGCTGGACTTGCAGAGCTGGCTCCTCTGCAAGGACAAGGGTTAGAAAAGCAAGTCCTGGGATTGCAGAAAGGACAAC
+
CC@FFFFFHHGHHJJIJFHHIICHIGIJGIIIJJIJIGDGHGIIJJJIIHIIIGIJJCHIHJJCGGHHHFHD@BDFEEEDECDACCDDCACCDDDB?CB<
@2B4
CGTACAAACTACATCAGGAGATATGCAAACATATCAGATCCGAACTACACCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATGACCTCTCCTGTGACTC
+
==:<+2,A+<?AC72?@+++37AB77++22:*1*11???AA=A1=5=7>)9=<A377.>=8=).87==A>A2(.(7.;?@(;(;>5;(-(-((,,,,:(,(
@2B5
GATGACTTGATTAGAGACCAAGGATTTCGTGGTGATGGAGGATCAACCACAGGTTTGTCTGCTACCCCCCCTGCCTCATTACCTGGCTCACTAACTAACGT
+
@<@DDDD>D>FDDFBFB3+ACEFA3<?9C+?D):<4C@?DE739B>;?=1(8C88@@8).=.7@@C;;/=?=?(,5>@>;54444<(+4:>>>>((4::8(
@2B6
GTGGAGCCTTTGGAGAAGTGTATGAAGGAACAGCAGTGGACATCTTAGGAGTTGGAAGTGGAGAAATCAAAGTAGCAGTGAAGACTTTGAA
+
CBCFFFFFHGHHHIJJJIEHIIJJGJIJGIJJJJJIFHIJFGIIGGGIJGHDGHHFGIAFGHIHHGIJJJJJA?EHHGEFFFFFFEEEECC
@2B7
CATAATTACATGCGGTAAATCTCATATTTTCTTCTGGACCTGGAGCGGCAATTCACTAACAAGAAAACAGGGAATTTTTGGGAAATATGAAAAGCCAAAAT
+
@@@FDDDDHHHHHJIFHIGIJJJJJJIJJJJJJJIIIGGGIIIIIGGIJIHIIIIJJJJGHFHGCEFDFECDCD@CDDDDDD<CDDDEEDEDCABDCC?BD
@2B8
CAAGGCTTTAAGAAGGAGTACCACGACCCAGTGTATGAACACAACACCATGGTTGGCAGTGCGGCCAGCCAAAGCTTTCCCCCTCCTCTGATGATTAAAC
+
;;?DDBFFHHFHHIGGEHIGIGIGGEEGIHIHGFGHIBC400?BFDHGH@GD.=@<CHE7?CEBB?BDDDAA?59@CDCDDCBB@B9A:ACDAA@CEACC
@2B9
CACTGACGCTCCACCGAAAGATGATTTTTGGATACCAGAAACAAGTTTCATACTTACTATTATAGTTGGAATATTTCTGGTTGTTACAATCCCACTGACCC
+
CCCFFFFFHHHHHJJJIJJJJJJJIJJJJJJJJIJJJJJJJJJIIHIIJIJJIJJIIJJIJIJGHHHHHHFFFFFFFEEDEDDDDDDDDDDDDDDDDDDDD
@2BA
TGACTGGACAGTTACCTTATTCAAACATCAACAACAGGGACCAGATAATTTTTATGGTGGGACGAGGATACCTGTCTCCAGATCTCAGTAAGGTACGGAGT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJIJJJJJJJJJJJJIJJJJJJJJJJJIJJJCHIJIJJHHFFCEEEECDCCDDDDDDDEDDDCDDDD@CDDDDD8
@2BB
AGTCCATACCAGATAGCAGCTACCCCATGGACCACAGATTTCGCCGCCAGCTTTCTGAACCCTGTAACTCCTTTCCTCCTTTGCCGACGATGCCAAGGGA
+
CC@FFFFFHHHHHJJJJJJJJJJJJJJJJJIJJJJJJJJJJJIJJJJJJJJJJJJJJHHHHFFFFFFEEEEEEDDDDDDDDDDDDDDDDDDDDDDDDDDD
@2BC
CACCAAGGGAGCATCCCCTCAGTCCTCACCATGCCTCAGGAGGTCAGGGCAGCCAGAGAGCATCCCACCTGCTCCCTGCTGGAGCAAAAGGCCCCAGCAA
+
CCCFFFDDHHHHHIIJJJJJJJIJJJJIGGIJFIJJI>AFGIBBGHEBECCBGH>A@@CEEHHFFEEFDEEDDDDD?CBCDC?BDDCCDCBBABD@BBDD
@2BD
CAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATG
+
@@@FFFDBFFDFHGIIEGEHBGHGIGGDGCFFHBFIH<DFGHIIIDGHHIIHIDGIIGIIIIGEIIIFGGHFFCDDDDDCDCCCCDDDDDDCB>A@CDDDD
@2BE
CAGATGACTGCAGTTCAGAGGTAAATGGTTGCAGTTTTGTGATGAGAACAGGAAAGCCTACAAATTTATTAAGGGAAGAAGAATTTGGTGTTGATGATTCT
+
CCCFFFFFHHGHHGIIJJIIIFHJIHJJHHIJJIGIJJJGIIIJIJJJIIIJJIJJJJJJJIIIJJJIJJJIJJJGHHHFFEEEEEEE?AABDDDDDEEDD
@2BF
ACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGT
+
C@@FFFFDHHHHHGHGIJJJJJJJJJIGIJJJJJIIIIJJIJJIGGHJGIJJJJJIJIFGHIGIJJJFHHFFDFFCDECEEDDCDDCDDCDDDDDBDDDDD
@2BG
CTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCT
+
@@@DFDDDDFHFDGBGHGGBGEBFFGGIIHAHCGHGGIIDHGIEHIIIIDC=C<=CFFGGECGIGEHGCEHHFB8/3;;>AA3>C(:@C@>?@A>CCCCA:
@2BH
CTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCC
+
:81+ADDB;:DD8;22<:A?FFI??<BDD??BDBDC@B?@D<D?@A@@CD>9AADDD@CD>C??CDDADD>6>@????=?<>8AA:>>><>??><?A>:
@2BI
CTGATGAGTAAAGAATCTCCTGTCTCTGCTGGAAATGATGCCTATGTTGACCTTGATCGTCAGCTGAAGAAAACTACAGAGGAACTAAATGAAGCTTTGTC
+
@@@7DDDDDFBHBHIIG@CFHH?FC?FEGHHCGG@HEI<GADHECFHIG@GICBFGIEIDEA@FDHGG@@GGGIIIFEEFEDBDBDCCC<CCCCC@CCC>:
@2BJ
GCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTAT
+
@?@FFFFFDHHFDBGHIB;CEHDHHIIIIIIGIIIGIIECGGIFFHGGGGHDHIIII9FGH4@HGIGIHGDFF@CDDFBCECE@ACDDDBDCDDBCD?CAA
@2BK
ACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACG
+
@@@FDDDDFFFFDIAH@@FHIICHGGGEABGIGHGIIIGIIIDGIHHGEIIHGGIIGGCEGGGEEHDDFFFCECECCECDCCCCCCCCCCCCCBBBBCC@B
@2BL
GGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACTCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGT
+
CCCFFFFFHGHHGJJJJJJJJJJIJJJJJJJJJJIJJJJJJJJJJJJJIJJIJJJIJIJIHHHHHFFFFEDEDEDDDDDDDDDDDDDDDDDDDDDDDCCD@
@2BM
CTTTAGCAGTGCCCTGGGAAGGCTCTTCAGGAGCCATGTGGGGAGATGACAGAGGTACCCCCATGGCTCAGAGTTATGATCAGAATCCTTCCCCTAGAGC
+
@@@BDD?DFBFHHE9;3FHG:;E<AEBCGHIIIIE>G>GGHGD(7'888=7=CHI.=CEAHEDDDEACCC>:ACDC>AA>A@:@@:AACCCC??<??A>@
@2BN
CTGGAGAGAGATATGTCTACAAGTTTGTGTGTGATCCAGAAGCCCTTTTCTCCATGGCCTTTCCAGATAATCAGCGTCCACTGCTGAAGACAGACATGGA
+
BCCFDFFFGHHHHJIJIJJIJJJIIJJGHGHHGIGGIIIIIJJJIJJJIJIJJIJEIIEIJJJIJGGCHIIHGIGHEDFFFEEEEEEDCCCCDDDDDDDD
@2BO
ACAAATCAAAGCTCATGATGGCAGTGTGTTCACACTTTGTCAGATGAGAAATGGGATGTTATTAACTGGAGGAGGGAAAGACAGAAAAATAATTCTGTGGG
+
CCCFFFFFHHHGGIJJIGHIJDFHAFAFEHHIJJJIIIGIIIGBFGFGHGGGGGIJIJGHIIIIJEHHI@FD@EEHFFFACCEECCDD??@C@CDED;ACD
@2BP
CTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAA
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHFFDEEEEDDDDDDDDDDDDCCDDDEDDDDDDDDDD
@2BQ
CAAAGGAAGGACGTCCTATGTACCAACTCCAGATGTCTGAGCCAAACATCCCCTTCCCACCACAAGGCTTTAAGCAGGAGTACCACGACCCAGTGTATGA
+
@@CFFFFFHDBHHEEHGIIIDHIIIGDHIGIGHIGJIJJIJCGHGIIJJHIJJIIIIGEEIIIHGGHFDFFFEEECEB5?ACDDDDDBDDDDDCCADDED
@2BR
AGCGAGAGGGAGACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTAC
+
BCCFDFFFHHHHHJJJJJJHIJIIHIIGIIFHJAFHFHHJHHHHGFFFFFEDDDDDDDDDDDDDDDDEEDDDDDDDDDDDDDDDDDDDDDBDDDDDDDDDD
@2BS
CTGATGCCCAGCCCCATCATGCACCCTCTGATCCTGAACCCCCGGCACTCCGTGGATTTCAAACAGTCCAGGCTCTCCGAGGACGGGCTGCATAGGGAAGG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJHHHFBEFEEEEEEEDDDDDDDDDDDDDDDDDDDDDCDBDDDDDDDDDDDD
@2BT
AAGAGCTTCATTTGCAAAGAATAAATCCAACTACAGTGAAAATGAAAAGTTCTGTCTTTGATGAAGACAAAACTTTTGTAGCAGAAACATTGGAAATGGGT
+
@@@FFDBDHFHFHHFIJJJJIIJJEIEGHJGIIDEH?EBHGIEGCGGIG@F@GHFHEHGE??FGEHIEHIJJIJJIIG6@E:EEGGCDCED@C@CDCCCD;
@2BU
GCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGC
+
CCCFFFFFHHHHHFHIIJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJIJIJJIIJJJJJJJHHHHFFFFFEEEDECDDDCDDDDDCDDEDDDDDDDDD
@2BV
GGAGGTCAGGGCAGCCAGAGAGCATCCCACCTGCTCCCTGCTGGAGCAAAAGGCCCCAGCAAACTTCCATATCCTGTTGCCAAGTCTGGGAAGCGAGCTCT
+
;1;BDAD;A?3?=)<A?<F3C13C@E@1::?;B;09:69?)*BDDD>;;.8)5(.-'556)7??>>(>>B;(6>>(;3(>AA>9,,(5=??:0<5<>>5:A
@2BW
CAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACC
+
CCCFFFFFHHHHHIJJIJIJJJJJJIJJHIJJJJJIJJJJJIJJJJJJJJJJHIIJJJHHGHHFFFFEEEEEDDDDD?BDDDBCDDDD>CDDDDDDDEEDD
@2BX
AGAAAAGTGCCTGTACAATGTCAGTGCCTATGATCAGAAGCCACAAGTGGGAATGAGGCCCTCCAACCCCCCCACACCATCCAGCACGCCAGTGTCCCCAC
+
CCCFFFFDHHHHHIIJJJJJJJJIHJJJJJJJJJJJJJJJJJJJJJIGIJJJJJJJJJJJJJJJJJJJJHHDDB??BB@CDDDCCAB5<?BDCDCCDDDCB
@2BY
GTTAAATCTTTAAAGCAAGAGAAAGCACAAGTTTCATTGAGATGAAGAGAGCTAGAAATCATTATTAACCACAACAGGGCAGAAAATGCACAGTCATGTG
+
===?;<A?>A>,>4?<+?+33+3+3+2<+?+*1:@4*::*7?AB*?AB?))0*777?=*).=A7>)=7).=55AAA>=7<=45>;;6=(53(5-;:=;5(
@2BZ
GAATAATCCTATAGCAAAGAAGGAGCCACACGACAGGGGTAACCTGGGGCTGGAGGGAAGCTGTACTGTCCCACCTAACGTTGCAACTGGGAGACTTCCGG
+
C@@FFFFDHDDBDHIGIGIIJIFGGIDGEGHGFDHGDII@FHIIHJJIGIIGEEEEDBD;AEEEDDE>>@CCDDDDCD@BACB>CC@ACCDB?@@@@CC@B
@2C0
ATTACGACAAGCTGAGCCGGGCCCTCCGTTATTACTATGATAAAAACATTATGACCAAAGTGCACGGCAAAAGATATGCTTACAAATTTGACTTCCACGGC
+
CCCFFFFFFHHHHGGHJIIGGGGIJIJIHIIJJJJJJJJJJJJJJIIIJJGJHHHHHHFFBFFEEDDDDDDDDDDDECDEEDDDDDDDDDEDDDDDDDBBD
@2C1
GGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTT
+
CC@FFFFFHHHHHIIEHGGGGGGHGECAIHIJHJGGIIIGGHHGHIFIIIJJJJIJJJGEGHCEHHHFFFFBBCBBABDDBDDDBB:>CCCCCDD(5&2<
@2C2
CGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCG
+
1:1+=@?B?:AADG?:@CCE??F1?DFGA9B?DBF?*)B@5;8;C54:9B?;@>.;AAA;A:;>@@59?A3?B5()&)9@BBB5<<?<:>:>>:@3>>@B.
@2C3
GCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCC
+
8:?D=DABFDHHFBDAFFHH@EFGGBHGGCDDGI4DHFHGC@@BCE@F8FF>@C8@CFHIE@>@CE?;?EECD@;@>@@;>>?BBBBBBB@C@C>:A>B@C
@2C4
ATCGACTTTGAGACCCTGAAGCCGTCCACACTGCGTGAGCTGGAGCGCTATGTCACCTCCTGTTTGCGGAAGAAAAGGAAACCTCAAG
+
CCCFFFFFHHHHHJJJJJJJIJJJJJJJJJJJJJJIJJJJJJJJJJJJJJHHHHHHHFFFFECEEDEDDDDDDDDDDDDDDDDDDDDD
@2C5
ACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGT
+
CCCFFFFFHHHHHIJJJJJJJJJJJJIIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJHHHHHFFFFFFEDDDDDDDDDDDDDDDCDDDDEDDD9<5
@2C6
CCTCAATCTAGCACAGGGGGATACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGT
+
@@@BBBDDFCB:CAGCAF>:))1??DCFD;B8F28?DFBFCF<B=C;=@CEEIIC:?AAEFF>B;?@BA=3?B-;;>3-?B<@=BAB<<<B3??@B>8?B4
@2C7
TGCAATCTCTGAAGATCATGTGGCCTCAGTGAAAAAAATCAGTCTCAAGTAAAGGCCAACCAAGCC
+
CCCFFFFFHHHHHJJJJJJJHIIJJJJJJHGJJJIJJJJJJIIHIJJIJJIJJJIIJJHHHIJHHH
@2C8
CAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGAC
+
CCCFFFFFHGHHHJJJJIIJJJJJJJIJJIJIIIIIJJJJJJJJJJJIGJIJJJJJJEIJJIJJJJIIIHHHHHFFFDDDDDDDDADDDDDDDDDDDDDD
@2C9
CTCGATGGAGTGGGTCCCATCAGTTTGAACAGTTGTCTGGATCCATTTTGTGGATGGCACCAGAAGTCATCAGAATGCAAGATAAAAATCCATACAGCTTT
+
CCCFFFFFHHFHHJIJJJJJJJJJJJJJJJJJIJJIJIJJJJJJJJJJJJGIJJJJJJJJJJJJJJIJGIHHHHHHFFFFFFEEEEEEDDDDDDDDDDDDD
@2CA
GGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGC
+
CCCFFFFFHHHHHJJJJJJIJJHIJJJJGIIJJJJIIJJJJJJJJJJHHHHFFFFFFFEEEEEEDDDDDDDDDDDDDDCDDDDDDDDDDDDDEDDDDDDDD
@2CB
GCTTCCTGGCTCATCCCAGCAGAACAGAAGGCTGTATGTTTGAAAAGGGCCCCAGGCAGTTTTATGATGACACCTGTGTTGTCCCAGAAAAATTCGATGG
+
CCCFFFFFHHHHHJIJJJJIJJJJJJJJJIJJJJIJJJIJJJJJJJJIJIJJJIJJJIJHIJJJHGGGHHFFFFFEEEEDDCDDDDDDDDDDDDDDEEED
@2CC
GGAGACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTT
+
?<=ADDDD<DF?CBFE@FBBGF8?DFFEF@FFBDF@BF;==8@EA:::BDDB3/9>>>;(;::;>ABA>:>?28:>AB9>05@<B?BBBBB1<:4+:::A
@2CD
CTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGG
+
CCCFFFFFHHHHHJJIJJJJJJJJIJIJJJJJIJJJJJJJJJJJJJJJJJJJJJJIJJJGHHHHFFFFDDDEDDDDDDDEDEDDDDDDDDDDDDDDDDDDD
@2CE
ATGCTGGGCCGGCGCCCTGGGGCCCCGGAGAGCAAGTGCAGCCGCGGAGCCCTGTACACAGGCTTTTCCATCCTGGTGACTCTGCTCCTCGCTGGCCAGGC
+
@@@FFFFFHHHGHJJJJFGGJJIJJJJIIHFFFFECEEEECABBDBDDDDDDCDCDDEDCBDB?CDDDDEEDDDDDCDCDDDCCCDDDDC9BDBDBDC@BD
@2CF
AGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACC
+
CCCFFFFFHHHHHJJJJJIJJJJJJJIIIJJJJIJJIJJJJJJJJIJJJJJJHHHFFFFFEECEEEEDDDDDDDDDDDDDDDDDDDDDDDDDDDEDDDDDD
@2CG
CCCGGATGTAATCAACACCGCTTTGCCGATAGAATATGGTCCACTTGTGGAAGAGGAAGAGAAAGTGCCTGTGAGGCCCAAGGACCCTGAGGGGGTTCCTC
+
CCCFFDDDFFHHHJIJIIIJJJJJJIJJJJIIIJJIJJJFHGIJJGICHIIGGIIIHHGHFFFFFEEEEEEDCEDDDDDDDDDDDDDDDDDDDDDBDDDDD
@2CH
GTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGC
+
??<BDD?4DFHDFE@?FBABDB<@81?CCDHEHGGAD<??BBDF>BAFAA@E?=EDEEB@CC>@6@>CCA>ACCC?BCB<?????8>C@CCBBCBBB?B(+
@2CI
CGATGGAGTGGGTCCCATCAGTTTGAACAGTTGTCTGGATCCATTTTGTGGATGGCACCAGAAGTCATCAGAATGCAAGATAAAAATCCATACAGCTTTC
+
@@<DDFEDACFDDGFHIIIGGF@BF>HBDFHGG?FHGC>BGGGHHE@H9DBBBDGG@DFG@D>C=CCC@EHBFCHGFB>>BCCECAAA>>@@=@@C@CCC
@2CJ
CACAGTGACTCTTTCTCACTTTGATGAGAGCATGGCCTACATGCCGGAAGGGGGCTGCTGCAACCCCCACCCCTACAACGAAGGCTACGTGTATTAACAC
+
@@@FDFFFHHHHHIEHHIIJJJGHHCIIIJIJGGHIIIIGIIIICGEHJJIFIGEBEBFFFDEEEDD@BBDDDDDBDCABBBDDBDCCB8CCDDDEEDD@
@2CK
CTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATG
+
CCCFFADDHHFHHIJIIIJJJEGIJHHIJIJGIBGHIIIIIHHIJJJJIJHHHHFFFFDCBCEEDDEDDDDDDDDDDDDDDDDDDEDBBDDDDDDDCCDDD
@2CL
CCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACC
+
CCCFFFFFHHHHHJJJJJJJJJJFHIIJJJIJIIJJJJJJIJJDGIIJJJJIJJJJJJJJJJJJIJIJHHHGHFFFFFFEEEDDCDDDDDDDDDDDDDD
@2CM
TCCAAATCCAAAGACTCTGTGTGGGAAAAAGAAATAGAAATACTTATAGAGGAAAATGAGGACCTCAAACAACAATGTATTCAGCTAAATGAAGAGATTG
+
CCCFFFFFHHHHHJJJJJJHIHHIJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIIJJJJJJJJJJIHHGHFFFCEFFFEEEEEDDDEDDDDDDDDD
@2CN
CGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCT
+
?@@DDAE?FDFHFEDBD?GFCGDFBCHIIIIIIIIEGHFGAGGIGFDHIGGGE@FCCFCCFEGHIGH>CHHHEEDFC?@BBCCCCCCCCCCC>CCBBCBBC
@2CO
CTGCAATCCCTGCCCCGGTTCATCCTGCTGGAGCTCATGGCGGGGGGGGACCCCAAGGCCTTCCTCCGTGGGGACCCCCCTCGCCCCCGCCCCCCCCCCCC
+
CCCFDFFFHHFHAHGGGGAGGHBGIGHDHIFGAFIHIGGCGGG4;8@&)&&+(((2(+(+(+(34(+&++&&&()8((&0&0&)09&&&&)&)))&))0&)
@2CP
CCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGC
+
CCCFFFFFHHHHHJJJJJIJJJJHJJJJJJIJIJIJJJJJIJJJJJJJJJJJJJJJIJJJJJJJHHHHHHFFFFFDDDDDDDDDDDDDDDDDDDDDDDDDD
@2CQ
CTCACCTCTCAGACAACTAAGACAGATGACCCCCAATTGAAAAGAGAAATAAGGTTAATGAAAAACAGAGAAGCTGCTCGAGAATGTCGCAGAAAGAAGA
+
CCCFFFFFHHHHHIJJJJJJJJJJJIJJJJJJJJJJJJJIJJJJHIIJJJJJJIFHIJIJIJJJJJJHHHHFFFFFFCEDDDDDDDDEDDDDDDDDDDDD
@2CR
AGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGG
+
CCCFFFFFHHHGHJJJJJJJIIJJJJJJJJJIJJJJJIJJJIJJJJIJJJJJJJIJJJJJJJIIJJIHHHHFFDDDDCDDDDDDDDDDDDDDCCDDDEDDD
@2CS
CAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCC
+
CCCFFFFFHHFHHJJIHHJJFHIJIGIIIGIJJJJIIGIJCHHGJJIIGHIJJJJHHGFFFFFFDDEDDDDDDDDDDDDDDDCDBDDCDDDDDDDDDDDD
@2CT
GGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATC
+
@@7??)@3AB?B;BE;EFGIDGFDHEFA4DBHIEGG;G???BB>B8=CBEC@DHHC5@=@;C>?=;(5>ACCCBB?C?3@AA9995>A3:A@A:(38<?A4
@2CU
GATTGCAACTGGACAGATAGCTGGCGTGGATAAAGATGGAAGGCCTCTACAACCCCACGTCAGAGTGTGGGATTCTGTTACTCTATCCACACTGCAGATT
+
CCCFFFFFHHHHHIIJIJJJJJJJJIEGGFGIJIGGIIJJJJIIIIJJIJJJJJJJJJHHHHFFF@DCCDDDDDCDEEDDDDCDDDDCDDDDDDDDDDDD
@2CV
TGCATATTTTGATGAAAATTGGCTAAACAGAATCAAAACTGAAGTAGGAGATAATTGGAGGCTAAAGATAAGCAATTTAAAGAAAATTTTAAAAGGAATCT
+
CCCFFFFFHHHGHJJJJJJJJIJIJJJJIIIJJJIJJJGIJJGIHGHIEHGHIEIIJHICHHJJJJJIIIIIJJJHHHHGHHFFFFFEECEDEDDDBDCDD
@2CW
CCAACAGGCTTGCAGCCAATTTACTGGAGCAGGGATGACGTAGCCCAGTGGCTCAAGTGGGCTGAAAATGAGTTTTCTTTAAGGCCAATTGACAGCAACAC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJIJJJJJJJJJIJJJJJJJJIIHIJJJJJJJ@EIIGHHHFFFFFDEACEEEEDDDDDDDDDDDDDCCDDDDDDDD
@2CX
CTTGGCTTTGCTTTTTTTATTCTCTTCCACTTCCTCTTTCCTTTTGTGCTTTTCTTTTTTCTTTTCCTTCTTGTCTTTCTCCTTTTTCTTTGGTTTGTTCT
+
@@@DDFFFHHHHHIGGIIJJIGIJJIJJEHIIJGGIIJIFDHGIGIFEGGHIIGIJJJJJIJJHHFAHEDFFDEEEC@>CCEDDDDD5@CCACABB<BC>>
@2CY
CGCAAGTGCAAGCCCCAGATGAATTACGACAAGCTGAGCCGGGCCCTGCGCTATTACTATAACAAGCGCATTCTGCACAAGACCAAGGGGAAACGGTTCAC
+
?@@DD:A;FFDBFHAGGEG9F@HH42AEE:@GHDGGA@>DEHB>@8DE==E<DA;;>>;6;5@A@=?8;2=B(:44(:AB19333<880099?3<??BBC@
@2CZ
GGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCT
+
?@@FDDEFDAFBDEGII@EEA?FGHIIGGEGIGIEHGGIIIFIIHIGIDHIIIIIIGGGIIIGEACCDEHHFCCADFDCCEEA;ACCBBCCCACCCCCCC
@2D0
GCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCC
+
CCCFFFFFHHHHHJJIJJJJJJJFIJJJJJJJJJJJJIJIJJJJJJIJJJIJJJJJJJJJJJJJHHHHHFFFFFEEDCEDDDDDDDDDDD@CDDEEDEDDD
@2D1
CCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACA
+
CCCFFFFFHHHGHJJJJJIIIIJJIJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJHGFFCCEEDDDDDDDDDDDDDCCDDDEDDDCDDDDD
@2D2
GTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGC
+
CBCFFFFFHHHHHJJJJJJJJJJJJHIJJJJJJJJJJJJJJJJJJJJJJJJJHHHHHFDFFFFEEEEEEDEDDDDDDDACDDDDDDBDDDDDDDDDDDD
@2D3
AGCTAGAAATCATTATTAACCACAACAGGGCAGAAAATGTACAGTCATGTGATACTCAAGTAAGCTCTTTATTAGATGGAGTTGTGACTATGACAAGCAGG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJHIJJJJJJJJIIJJJJJJJJJIIJJJJIJJJJJJJJHIHHEFHFFEEFFEEDEDEDDDDDDD
@2D4
AAAGAATTGGATCTGGATCATTTGGAACAGTCTACAAGGGAAAGTGGCATGGTGATGTGGCAGTGAAAATGTTGAATGTGACAGCACCTACACCTCAGC
+
@@@FFFFFHGHHHJJJGIJJJJJJJIJIJJCGIIIJIHIIIJJJBFGGIIIJ8DEDFFGHEIEFGGIJIEGCGFAEHHCHBDCBBAEDEEDCCCDBDDC
@2D5
GTACAGACTGAAGAGAACTAACCACAGGTTATTTTGGAATATCCCAGGCAGCCATTAACTTTTTTTCCTTCTTATCCTCCTTCCAGCTATTCTTCTATTC
+
;-;@@)>(=)..)=.)))))))()3@?(@.).:))>3)):?))):>)<(<(((<)>).>:))).'9))):)(.(.(:;(9;((((,:2(77((7(,,(((
@2D6
CTGTTGTTTCATGTTTCCTGTGTTTAAAATCATTCTTAATACTGCTTTTTAGCCTTGCTATACATCCTGACAAAATTAGGATTGCAACTGGACAGATAGCT
+
CCCFFFFFHHHHHJJJJIJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJIJJJIJJJJJJJIJJJJJJJJJJIHHHHHHFFFFFEEDEEDDDD
@2D7
TGCAAATACCATAATTACATGCGGTAAATCTCATATTTTCTTCTGGACCTGGAGCGGCAATTCACTAACAAGAAAACAGGGAATTTTTGGGAAATATGAA
+
;?<DDDDDFHDFDDFGGGHGGIAFFFGHIIIGIIEBFCHIGF9D<BGGEDBA9;D;AGGHFC:C=?BBCD@@@@CCCBAB@BBBCCCCB>>BCAACDDCC
@2D8
TGGAGCTGCAGAGCCCTGAGTACAAGCTGAGCAAGCTCCGCACCTCGACCATCATGACCGACTACAACCCCAACTACTGCTTTGCTGGCAAGACCTCCTCC
+
11:D4+A?8D3DD;?E@E3FAFFFB3<AEEICEDB;:?9@<@D<?DADD@@;A;A7A>CA'9<>AA;5(,88?8>AA>>A4>(:>>A>29:8<<<>A<<9>
@2D9
CAGCAGCAGCGATAGCTCCTCGGACAGTGACAGTTCGACTGATGACTCTGAGGAGGAGCGAGCCCAGCGGCTGGCTGAGCTCCAGGAGCAGCTCAAAGCCG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJIJJJJJIJJJJJJJJJJJJJJJJIJJIJJHHHFFDDDDDDDDDDDDDDDDDDDCDDDDDBBDDDBDDDDDDCDD
@2DA
CTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGC
+
B@BFFFFFGHHHHJIJHJJJJJJJJJIJJJJGIJJJJJJJJJJJJJJJIJGIIJJJJJJJIJHHFFEDEDEEDDDDDDCDDDACCDDEDDDCCDDDDDDDC
@2DB
AAAAATCCATACAGCTTTCAGTCAGATGTATATGCATTTGGAATTGTTCTGTATGAATTGATGACTGGACAGTTACCTTATTCAAACATCAACAACAGGG
+
C@CFFFEFHFHFFHGIGGEIGIIGHCHHCHIGIGHIEGIGGIIGEHHDHIH?BGFCFGGGIJHEEJIJGGGGJIJJGIJEHIDHEFEHHACDDBDDDBCB
@2DC
TTCCAACCCCGACGAGATTGAAATCGACTTTGAGACCCTGAAGCCGTCCACACTGCGTGAGCTGGAGCGCTATGTCACCTCCTGTTTGCGGAAGAAAAGG
+
?<;BDDDDFACFFHE<6EEHGIIGCH>@FFGG8BF@BC@DFEE3@@;A<C3;?CCCBC>@?;>>9ABCB@BBBA4@A@CCABC>C>@?<@B9<@ACCCCB
@2DD
AACAGAGTCAAAAATTACAGATTCAATTTCAGCAATTACAGGCTAGTGAAACTCTGAGAAACAGCACTCATAGTAGCACAGCTGCAGACTTACTACAAGCC
+
@@@FFFFFHHHHGIJIJJJIIJJJJJJGGHHIIJJGHIIJJIGHIIGIGIJGIHIJDGHHIIJIJGIHJIIJGGEGGGHFFH>CEFE@CEEEEEECDDDDD
@2DE
CGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGG
+
C@CFFFFBHHHHHJJIJGHIGIJJJHGIHGIIJJIGIIGBHEEIGFGIIJIJIGIIGGGEGIIFHHHHFFFFDEECCCC@CCCDDDCDDDACDDBDDDDDD
@2DF
CTTTCTGAACCCTGTAACTCCTTTCCTCCTTTGCCGACGATGCCAAGGGAAGGACGTCCTATGTACCAACGCCAGATGTCTGAGCCAAACATCCCCTTCCC
+
CCCFFFFFHHHHHJJJJJJJJJJJJIJJJJJJJJJJIJJJJJJJJJJJJIJJJIJHHHFFFFFEEFCEEDDDDDDDDDEDEDDDDDDDDDDDDDDDDDDDD
@2DG
GACTAGTTAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCC
+
<;?DDDDDFDF?DHGGIGGIGBE<C3;?8?:6BDGGIGGAHIIIIGDCEHIIEHCEDECDDDE;CCCAACCACCACCCC?ABB(::@CCB?<?<BCCCBB
@2DH
AGCGGTTTCCCTTGTCTGTAGTCCCGAGTTAGGATGGAGAGCGCAGCAAAGGGCTTTTGCGTCCATGCTTGAGGTCCAAATCCAGCTCTGGCAATCACCCG
+
0((2(((:))).9).))))3))==)(-@(@))=)<)-.()7((((7'()).83=77)8))''3=((((--7;<(,,:7(,(7((7(+((((4(+++((((0
@2DI
CACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGAT
+
CCCFFFFFHHHHHJJJJJIJJJJJJJJJJJJIJJJJGGJJJJJJJIJIJJJJJGGIJJJJIJHHHHFFFFEDEEDDDDDDDDEEDDDDDDDDDDDDDDDDC
@2DJ
GGAGCAGCTCAAAGCCGTGCACGAGCAGCTTGCAGCCCTCTCTCAGCCCCAGCAGAACAAACCAAAGAAAAAGGAGAAAGACAAGAAGGAAAAAAAAAAA
+
8:??DDDBB?CDB:C>C?8CF98E<@DAECBC=FCH@BFGFG=)=8BDDFE;;C;CE>EEE?5=?A9ABCC@@@B9?BC3?<CC8??32?CCCBBBBBBB
@2DK
CTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTAT
+
CC@FFFFFHGHGHIJJEBEEGEEHHECHHCHIGGIIIJIII6@AEHIGGGIH=AHGHFFFFEFEEEEDDDDDDDDCDDCDCDDCDBBDDDDDDDDA?BDDD
@2DL
TTGCTCCTTTACAAGAGAGTCAGGAGTCTTACACAACTGGGACTCCCAAAGCAACATCTTCTCACCAGGGCCTTGGAAGCACTTTGCCTAGAAGGGGAACC
+
1:>A++2<C,7+AA<327A<<A4+<?BA<?>=<A<1?*?A3))):><9;5>=>A9=)=;7)..875..1:15()77>>56>>=?5=;?(,(5;(933.988
@2DM
CGACCCGACCTGCGGTGCCTTCAGCCCCAACCAAAGACACTAGGGCACCCCCTTCACAGACACAGAGGTCGGAGGGCGGACTGGGGGGGGCCCAGACCGGG
+
(-(58((00(-:6<?(3())..)):3(7(000<3...3)))).)()-65-,59((9(-7(((((,7(((,'&&)0&&&&&&&(+66&)&&&)&+865/&&0
@2DN
AACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAATCACTGCACCTCCATCCTACCCTCC
+
CCCFFFFFHGHHHJJJJJJJJJJJJJJJJGIJJJJJIJJJJJJJJJJJJHIJJJJJJGIJJJJJJJHHHHHFFFFEEEEEEDDDDDDDDDDDDDDDDDDDD
@2DO
GTCATCTTCATCCTCAGAAGACAGGAATCGAATGAAAACACTTGGTAGACGGGACTCGAGTGATGATTGGGAGATTCCTGATGGGCAGATTACAGTGGGA
+
@@@DDFDFHHHHHIIJJIJIIIJJIFIIIIGIIJIJHIJIIJJJJIIIHJJJIIHIJJGI@DCAEEHHGHFFFDCCEEE@ACDDDDDBBDDDDDD;CCDA
@2DP
GGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTC
+
CC@FFFFFHHHGHIFGHIIJGJIHHIJJJJIIIIHIGJJJJJIIJJJFHIJJEIGIIJGIIGGEHHGGIHHHHEFFFFFEEEECDDDDDDDCDDDDDDEDD
@2DQ
TCTCTCAGTCCAACCCTCCTTCGGAGTTGCACAAGGTCCACGGATCCAGAAACAAGCCCACCAGCTTGTGGAACCCAACGTACGGCTCCTGGTTTACAG
+
CCCFFFFFHHHHHJJJJJJJIJIJJJIIJIJJJJJJHHJJJJJIJJIJJJJJJJJJJJHHHFFFFFEEBEDDDDDDDDDDADDDDDDDDDDD>CBDDDD
@2DR
ATTTTTAGAGTTGACAGAACAGAGTCAAAAATTACAGATTCAATTTCAGCAATTACAGGCTAGTGAAACTCTGAGAAACAGCACTCATAGTAGCACAGCTG
+
<:=DDDDBAA<AAEGGDBCC?FIEBF@BHBA?E9?CG9?C@FHIGI9DA?BBBDD@D@BCCC2==CAF=C77)7=CDH;C7?7?B??@CC>.>C:;;=@55
@2DS
AAAACATTATGACCAAAGTGCACGGCAAAAGATATGCTTACAAATTTGACTTCCACGGCATTGCCCAGGCTCTGCAGCCACATCCGACCGAGTCGTCCATG
+
CCCFFFFFHHHGHJJJJJBIHIJJJIJJIIJIJJIJIJJIJJJJJJJJJHIJJIJJHHIJIJHHHHGFFFFEEEEEEDDDDDDDDDDDDDDB@CDDDDDDC
@2DT
CCCACGTATGAGTCGGAGGAAGAGGACAAGTGCAAGCCTATGTCCTATGAGGAGAAGCGGCAGCTCAGCTTGGACATCAACAAGCTCCCCGGCGAGAAGCT
+
@@@DFFAAFDFHFIGIFEGA?CCEGHGGCDFGHGHEHGIEGECGIH<CCCGGHCDEGEEDFDDDDD@ADDD?@@>CCA@C9@B?8+>C@9>BDBBD>BCCC
@2DU
CAACTACAGTGAAAATGAAAAGTTCTGTCTTTGATGAAGACAAAACTTTTGTAGCAGAAACATTGGAAATGGGTGAGGTTGTTGAAAAGGATACAACAGA
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJHIJIJJJJJJJJJJJIJIIJJJDHEHHHHHFFFFFEEDDBCDDDDDDDD
@2DV
CTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCAC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJFHIJJJJJJJJJJJJIIIIIJJIHHHHFFFDDDDDDDDDDEDEEEEEDDDDDDDDDDD
@2DW
CTGTTACTATCCGAGTTTTACAGTGGAGGAAATCGAGGCACAGAAAGGCTTGCAGCCAATTTACTGGAGCAGGGATGACGTAGCCCAGTGGCTCAAGTGGG
+
B@CDFFFFHHGHHJJFHIJJJJJFGEHIJJJJIIJIIJJJJJJJJJJJIJJIJJJIJJJHHHHHHFFDFFDEDDDDBDDD?BDDCDDBACCBBDCDD:ACD
@2DX
CAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJHIJJJJJJJJJJJJJJJJJJJIIJIJJJJJHHHHHFFFFEEEEEDDDDD=BDDDDDDDDDCCDDDDDDDEEDD
@2DY
AGGCAAGAAGGCTTCCTGGCTCATCCCAGCAGAACAGAAGGCTGTATGTTTGAAAAGGGCCCCAGGCAGTTTTATGATGACACCTGTGTTGTCCCAGAAA
+
CC@FFFFFHGHHHJIIGGGIJJGGJJIIGIJIDGCGHEGECGGGDGIGIIEHIJJJJIIFGGIHFHFBDBDFECCCCCEDDCDDDD@@CCDCDCDDCDCD
@2DZ
CTCATTCAGAAGAGGTACCCGAAGAAAAAGGACCTCGTTTCTCTGGGAGGCAAAGAGAGTTCAGATGGGATGAACCTGGGATTGAATAACCAAACAAAG
+
79((:))28?@))(<)22).(<((()))(1(2(:)9(9(03)0)))0((---<.890;().)).))..(90(..5(,93(,,;((3(,,,+885((((3
@2E0
CTGGGACGCGAATTGAAGAATAGCATCACTTAAAAACAGGGGGGATTTTTCCTTTTGGCTTTCGAGGGATAGAAAATATTTGTATATATTTATGGGGGTGT
+
;8;((((((-((((.==))).)):))0))0)))0))(.>91'-&0&6:<((+82+((&(6(((++(&&)+(+(+(38(((+(+43((5((((+2(2()&&&
@2E1
TTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAAC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJIJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJHHFFDDEEDDDDDCDDDDDDDDCDDDDEDDDDDDDD
@2E2
GGAGTTTGTCTGCTGAATGAACCCCAATACATTATCCTGGAACTGATGGAGGGAGGAGACCTTCTTACTTATTTGCGTAAAGCCCGGATGGCAACGTTTT
+
B@@FDDFFHHHHHJJJJIIJGIIJJJJJIIJJIJIIIIJIIIJJJJJJJGHIGGIIGGGHJIHGHHGHFFFFFFFDCDDDDDDDBBDBBDDDDDDDADDD
@2E3
AAAAATTCACCGCAGTGCATCAGAACCCTCCTTGAATCGGGCTGGTTTCCAAACAGAGGATTTTAGTCTATATGCTTGTGCTTCTCCAAAAACACCCATCC
+
CCCDFFFDFHHHHIIHIIHHIJJIJJJJIJJJJJJJJJJJJIJGGBGHIGJJJIJJJHHHHHFFFFDEEEDEEFCEECBCCDDDDDDDDDDDDDDDDDDDD
@2E4
CCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGGAGCTATGGTCAACA
+
?88ABDAA;FD=?<<1@8?+A?D?CBCEE9?>FD?D?9DFA><<CFC>8DF@F@8BFAF>@A@CA88B@BC>5;;>3;@<9(5<?19?8?4:4>>(:@:A
@2E5
CTGCTTTGCTGGCAAGACCTCCTCCATCAGTGACCTGAAGGAGGTGCCGCGGAAAAACATCACCCTCATTCGGGGTCTGGGCCATGGCGCCTTTGGGGAGG
+
@@@=DBDABFFDAC<GG:<<?;FA@E?9CEG>99<D;DDE;8:DBBDF<<FE<BD>B<@>A;;5??BBBDBA@@B99???@<<B3:?<59>>BBB?><B99
@2E6
CAGTTGTCTGGATCCATTTTGTGGATGGCACCAGAAGTCATCAGAATGCAAGATAAAAATCCATACAGCTTTCAGTCAGATGTATATGCATTTGGAATTGT
+
@@@ADDDBBFFDFGGFEFHG?<CGIGGIDCHAGHFCAGDFH>?DAFHGGIIGIIIIGEIIIBG@DFE:8;@ECGGC;7=>EE77;??>;;@>@@C35;AC>
@2E7
CTGTAGAGCCCACACCTGGGAAAGGACCTAAAGGTGTATATCAAATCAGCAAACAAATCAAAGCTCATGATGGCAGTGTGTTCACACTTTGTCAGATG
+
@CCFFFFFHHHHHJJIJIJJGIJJJGHGHHJJIJ:BFFHGIGIIJJJJJJJJJIJJIJJJJJJIIIJIJEHHHHFFBD@AAECEEDDDDDCCD@@CCD
@2E8
TTAGAAGAAAAGTGTGCTCTACAGAGACAGCTTGAAGACCTTGTTGAAGAATTGAGCTTTTCGCGGGAACAGATTCAGAGAGCTAGACAGACAATAGCTG
+
?@@DBDDDBDFBFFFGGIIJJGGI@FCGBHIJJGGHJIIDEHGGGHIIJ>@FHIH@EHFHGGEIJJFDC?BCCDC@>@CC??ACCCCACCCBBCCAACDC
@2E9
TCTAAAGCAAATGAAAGTTTTGGAGAAGAATCAAAAAAGATGGTGGAACATAAAGATTCTTTTGAGAATATACCTGTTGGGGAAGAAAGGAAGGAAAAAT
+
11=+4,<++<?4+2<++<<A,3?7?A><A+**11**1))00*9=7==*/..)=)=>A.8)87=)5(()...))7)))).('3('(,(,(((,((++(3((
@2EA
GCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCC
+
@@@FFF>DHHHHBEHIBGHIFIIIGEEIIIIIIIIIIIIHGIIIGGIIIIIHIIFFEHHFFFFDFEEEEDEDDDDCCDDDDCDDDDD99BDDCDDDDDDD
@2EB
GTGAACAGAAGCAAGAGTACATCCAAGCCATTATGATGATGGAGGAATCTGTTCAACATGTTGTCATGACAGCCATTCAAGAGCTGATGAGTAAAGAATCT
+
CCCFFFFFHHHHHJJIIIIJJJJIJJJJJIIJJJJGIIEIIJJJJJJJIJJJJJJJJIJJGIIHIJJGIJJJJJJHHHHGHFFFFFECE@C@CCDDDDDCD
@2EC
GTCAAGGTTGTATTGCAACCAATGTGTTGGAGCAAAAGCCTGTTTCGTTTTTGAAGATGGAAGTCCCCCCCGAGGTTGGGTTCAGGTAAGTATGGAATCTT
+
5;;(28)22)-))2442))(-(39).2.<()1)(9?)=(.)0)0))0(0((('(/;)/=))))..;.:33',''&&++&&+8((+8(2((+++88((+(((
@2ED
GGATTTCCAGAGGGAGGCCGAGCTGCTCACCAACCTGCAGCATGAGCACATTGTCAAGTTCTATGGAGTGTGCGGCGATGGGGACCCCCTCATCATGGTCT
+
CCCFFFFFHHHHHJJJJIJJJJJJJJJJIJJJJJJJJJIJIJJJJJJJJIJJJHIJHHHHHHGFFFFF?AACDDDDDDBDDDDDDDDDD@DBDDDCDDACD
@2EE
CAGGAAAACACGACATGTGAATATCCTACTCTTCATGGGCTATTCCACAAAGCCACAACTGGCTATTGTTACCCAGTGGTGTGAGGGCTCCAGCTTGTATC
+
CC@FFFFFGHFHGGGIJFHHHIHIJIGHBBBGHIJGIGHIIGIJIJIJJJJGGIIGIJJIIJIJJDHHHHHHFFFFBCC3=;?CABBDDDDDDCDDDACDE
@2EF
AGATAACTGTGTCCAGAGGACCCCCAGGCCATCCGTGGATAATGTGCACCATAACCCTCCCACCATTGAACTGTTGCACCGCTCCAGGTCACCTATCACG
+
??=BDDF8AABCCE9CFEGGII?FEHGBGGGBDFGB=@1*9?8?/?F9FEC>FAF;F2(;1)=EF@D;;;.;;.(..5>C333'8>:3@4>C>:A4:(>(
@2EG
CTTCAACACCCAAATTAATACCAAAAGTTACCAAAACTGCAGACAAGCATAAAGATGTCATCATCAACCAAGAAGGAGAATATATTAAAATGTTTATGCGC
+
@?@FFFFDFFHDDEFHBDHBHIIIGGBHHECEGIGHCGEHGCFCGGHHHIGIEBBBFHIGICFEFHGHGIGEEHF@;?=@CCDEDCCDCCC@>ADCCCC@=
@2EH
CAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGG
+
@C@FFFFFHHHGHJIIJJJJHIJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJIIJJJHHHHFFFFFEEEEEEEEDDDDDDDDDDDDDDDDDDDDDD
@2EI
GGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTT
+
@@CFFFFFHHHHHIGIIGHIIGGGHIGIJCHGGGIHGIGHIJGGDGHBHHGDHDFEIIIJGEHGGIGFHGEHFFEFEFCEDDBDBB?BDDCACCA>CCCC
@2EJ
CATCCAGTCACGGGAGCCCTCCCCGAAGAATTCCAACCCCGACGAGATTGAAATCGACTTTGAGACCCTGAAGCCGTCCAAACTGCGTGAGCTGGAGCGCT
+
8?<B1AD4AA<0))<?6E=9CEE)::6@0?<D?4?DB6@6A'5'''';;>6;>3(;('18AAA7(5<>933>>>>5&)50(48>4:;-0((+:>32<<35>
@2EK
GTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCC
+
@?@DDD;DFDAFAHDEFG=FEGGGDA;DHEBBEEHD@FGFHFGHIDACHEA==A=;>BD:;>A?@C?;?@B8,8&2<<@<<(++>+>44>:34:?@559
@2EL
CTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTAT
+
@@1BDDDDB:D???))<8:8B<GDBDFIIII@;BBF>DCFE;AA@9CECC>C)=EF@@)7.77ACCA@?BB>B@:AA:>,5:(59<12<B?8?<?:?B(:@
@2EM
GGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTAAGGC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJHHFFFFEEEEEEEDDDDDDDDDDDDDDDDDDDDDCD:@CC
@2EN
CAAAAATGAAGTAGGAGTACTCAGGAAAACACGACATGTGAATATCCTACTCTTCATGGGCTATTCCACAAAGCCACAACTGGCTATTGTTACCCAGTGGT
+
CCCFFFFFHHHHHJJGJGIJJJJJJJJJJJJJJJJIJJJJJJIJJJJJJJJJJJJJIJIIJJIJJJJJIIHHFFFFFFDDEEEDDDDDDDDDDDDDDDDD>
@2EO
CCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGACTGCATCAGGAGATATGCAAACATATC
+
?+?D;D:DD;8:C;2::EAFFEEEC@E9C?B1:E?<CBF<?BB?DDDDAEIDDD;CBCBD6/;:<???@DD>>;36;;3;>=>A>>3>AA29:5;>
@2EP
CAACTCATACACCGAAACCTGACCGGGCCTTCCCAGCTCACCTCCCTCCATCGCAGTCCATACCAGATAGCAGCTACCCCATGGACCACAGATTTCGCCGC
+
:=?DD?BDF?FFB@<@@@G@GFAEGI>H)?GIIIGGEBCFHGGG;@HAEA;=?D;B?CAC>ACCCC?;;AC@C?CACCB@?CCC@CC?@?<AA>CCC>B@<
@2EQ
CCGCAACTCCAGCTCCCTGGACCACCCGGATGAGCGGGCCCTCACCATGGGCGACCTCATCTCATTTGCCTGGCAGATCTCACAGGGGATGCAGTATCTGG
+
B@@FFFFFHGHGHIJFIIGJIJGIJGHIIGIGIGJIIIGHHDFFFEEEEED=B=@DDDCCC>CDEEEEDDCDDDDDBDDCDDDCCBDDBBBDDDDCDEEEC
@2ER
CGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCC
+
@CCFDDFBDFFFDHGFHIIJJEEHGHIGIIJJIEIIIJIJJIIJGGIIJJIIIGIIGGFFFFFCDDEEEDDDDDDDDDDCCDDDCDDDDDCCCDCDDDBDD
@2ES
GTAGGATGCCTGGATTTTTCAAAAGCAGATTCAGGTGTTCATTTATGTGTTATTGATGACTCCAATGAGCATATGCTTACTGTATGGGACTGGCAGAAGA
+
@@@FFFFDHFFFHGEHIIFIIJIJGIIGIJIHJIG9CCHGFCHHDHH<FBFDHIIDEHGGIIJJIIIEDFHGGJADEECHHECCHH;BBDDD??CBB?CC
@2ET
CCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTTATGGG
+
@@@FFFFFHHHHHJJEHIJHIIJIJIJJJJJJJJJIGFGIJJJIJJJJJJJIIJEIGIDHHGHHHHHEDDDDDDDDDDDDBD@CDCDDDDD?B<BDDDCCD
@2EU
CACCACTTCCAGCCTGCTGCTTCCTTCAGTTCCCCAAGCTCCTCCTCCAAATGCCAGCTCTGCTTAAAAGCTGTTCTTAGGGCTTACAATCGCCTTTTGA
+
11:+=2AA=?BDB+A2AC:A:<<+<CEDDFE>*:?E)1:9?B;)0)?BBDIE??8B8BB8@@))).).=)(7=7)7)7;)7.)((.;;(-55=6'8>(((
@2EV
TTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACC
+
@CCFFFFFHHGHFGEGGHEIIGH@GGIGHJDGHGGGGIIJIFJJEIFIJDGDGIIIGHGIIIHFCEFFFFFFACCCEEDDDDDDBBB<CBDDDDDDCDD@C
@2EW
GTCAAGCAGTAAACATGATGTGTCAGCACACCATGATTTGAATATTGATCAATCACAGTGTAATGAAATGTACATAAATAGTTCTCAGAGAGTAGAATCA
+
C@@FFFFFHHHHHIJJJIJJHIHIJJJJJJJJJIJJJIJJIJIJJJJJJJJJJJJJJIFHIIIIJJIJJJIIJJJIIJIIJHJJJHHHGHGFDFFFEEED
@2EX
GGAAGAGGACAAGTGCAAGCCTATGTCCTATGAGGAGAAGCGGCAGCTCAGCTTGGACATCAACAAGCTCCCCGGCGAGAAGCTGGGCCGCGTGGTGCAC
+
CCCFFFFFHHHHHGIJJJJJJJJJJIJJJJJJIJIHJIJJIJJJJJIGJJJJJJJJIHHHHHFFFFFDEEEDDDDDDDD@@CDDDDDDDDDD@DD<@CDC
@2EY
CAAATTCTCATTTTATTGCCTGGACTGGTCGAGGCATGGAATTTAAACTGATTGAGCCTGAAGAGGTGGCCCGACGTTGGGGCATTCAGAAAAACAGGCC
+
CCCFFFFFHHHHHJJJGJJJJJIJJJJJEIJJIJJJJJIJJJIJJJJGHIIEHHGIJJJIGIIGII=CHEFEDDDDDDDDDD>@CDCDCCDDDDBDDDDD
@2EZ
AAACAGGGAATTTTTGGGAAATATGAAAAGCCAAAATTTGTGCAGTGTTTAGCATTCTTGGGGAATGGAGATGTTCTTACTGGAGACTCAGGTGGAGTCAT
+
@@BFFFFFABHHHIJJIGHIJJJJIJJJJIIJIJJIIJJJJJIIIBGGHHIJJJJIGIJIJIICBHHHFGFFFFFFFFEEEEACDDDDDDDDCCD<ACCDE
@2F0
AAGAGATGGCATTATAACCCAGCTCACTGCTAATTTACAACAAGCAAGAAGAGAAAAGGATGAGACAATGAGAGAATTTTTAGAGTTGACAGAACAGAGTC
+
CCCDFFDDF<DDFIJIJJDGGGDIJJJIJBEA@EHIICHIGJGIIB>FGHEGHGIEIEICEHJEGHIECGIFEFECDFFEBCCCCCECCCC@CCDDDDA:@
@2F1
CAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCC
+
CCCFFFFFHHHHHJJJJJJJJJJJJHIJJJJJJIJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJHHHHHFFFFEEEEEEDDDDDEEDDDDDDDDDDD
@2F2
TGGCACAGATGGAGGAAATGAAAACACGGCATAAGGGAGAAATGGAGAATGCTTTAAGGTCATATTCAAATATTACAGTTAATGAAGATCAGATAAAGTT
+
CCCFFFFFDHHGGIJIJIJJJJJJJJJJIJIJJIJJGIIJJJJJJIJGHIGIIJJJJJJCGGFHHHHHGFFEFFFFEEFEEEEEDDDDDDDDDDDDDDDC
@2F3
CTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGC
+
CCCFFFFFHHHHHJIJJJJJJJJJIJJIJJJJJIJJIJJJIIIJJJJJJJJJIJJJJJJJJJHHHHHHFFFFEDDEEDDDDDDEDEEDEDDDDDDDDCDD
@2F4
GTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGAT
+
@@@BD?B?FDFBHED?<<?@ADA@9CAB?CGBGBBGFBF?B49B9?BFGIIE@=F===CFGIC@==CHEDE@7@D;;>>;;>CCA??B=8;=5>>:AACA3
@2F5
CTGAAGGTGTACCCGCCACTGAAGGGGAGCTTCCCGGAGAACCTGAGACACCTTAAGAACACCATGGAGACCATAGACTGGAAGGTCTTTGAGAGCTGGAT
+
CCCFFFFDHHHHHJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJHHHHFFFFFFDEEDDDDDDDDDDDDDDDDDDDDDDD>ACDDDDDDDDDDDDC
@2F6
CACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTGAGTTGCTAAGAG
+
CCCFFFFFHHHHHJJJJJJJJJJJIIJJJJJJJJJJJJJJJJJIJIIGIJJJJFIJJJJJJJIJJJHHHHHFFFDDDDDDDDDD@CCCDDDDDEDDDD
@2F7
CAGAAACATGGTGAGATTAGTTTTCTAAATGAAGAAGTTAAATCTTTAAAGCAAGAGAAAGAACAAGTTTCATTGAGATGTAGAGAGCTAGAAATCATTAT
+
CCCFFFFFHHHDFHIIJJJJJJJJJJJJJJJIJJJJJJJJJJIJJJJJJJJIJJJIJJIJIJCHHIIIJIJJJJIJJJJHAEHHGHFFFFEEEEEEDDEEE
@2F8
AGCACTTAATGAAGAGCTTCATTTGCAAAGAATAAATCCAACTACAGTGAAAATGAAAAGTTCTGTCTTTGATGAAGACAAAACTTTTGTAGCAGAAACAT
+
CC@FFFFFHHHHGIJIIJIJIJIJIJJJIIJIJJIIJJJIJJJJJJJFGGIJJIIIJIJJCHIJJIIJJJGJGIJJJIEHIHHHHHFFFBDFEEEEEEDDD
@2F9
CTCAAACTGGAGTGGGCATATGGTTATCGAGGAAAGGACTGTAGAGCTAATGTTTACCTTCTTCCGACCGGGGAAATAGTTTATTTCATTGCATCAGTAGT
+
CCCFFFFFHHHHFGIJJJJJJJJHJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJHHFDDDDDDDDDCDEEDDEEEEEDDDEDDDEDD@
@2FA
CTCAGTGAAAAAATCAGTCTCAAGTAAAGGCCAACCAAGCCCTCGAGCAGTTATTCCCATGTCCTGTATAACCAATGGAAGTGGTGCAAACAGAAAACCA
+
@?@FFDDDDHHGHIGIDEHGIIIIBHHHFBFHEGGGGBGIIIGIIIGIIIIHIIIGEHIGHHHHEE?CCEFD@D?@ACEDDCCDABCCCDDBCDDDDCDD
@2FB
CTTTGAAGAAGGGTTCCACAGACCAGGAGAAGATTGAATTCCTGAAGGAGGCACATCTGATGAGCAAATTTAATCATCCCAACATTCTGAAGCAGCTTGG
+
1=?D?DD>DBD:8EDEAEFE>FDAECCE>):CB@DECDEA<DDE<B<D@DIII<9<CEIE@CAAACDDCD3A;ADDD@>?@A7==A>>A>A>::=?AAA?
@2FC
AATTGGAGGCTAAAGATAAGCAATTTAAAGAAAATTTTAAAAGGAATCTTGGATTATAATCATGAGATTTTAGGACAGCAAATTAATGACTTTACCCTTCC
+
@@@DDDDDFHFHBHIGGEEGIJEHIIGGFHDHGGFBGIGIHGHCFFBHIGIIHEHGHIJACCDF@FCFHGGGHH;@AEHHFFDDCDECC@CCCCCDDDDDD
@2FD
CTCAGGTGGAGTCATGCTTATATGGAGCAAAACTACTGTAGAGCCCACACCTGGGAAAGGACCTAAAGGTGTATATCAAATCAGCAAACAAATCAAAGCTC
+
@@<DFDDDABF<DEHGHIEIEFCGHGIDIHIIGEFGGI?D<?DAH?HIIIIIGIGIEGGHGEGHGGGHDAC.=A;ADEDDE>C@CEDABBDDADCCDCCCC
@2FE
ACTTAATGAAGCACATAAGTCCCTTAGTACAGTGGAAGATTTGAAAGCTGAGATTGTTTCTGCATCTGAATCCAGAAAGGAACTAGAATTAAAACATGA
+
@@@DDAFFFFDHHIEEHIIGGHCHAFEHGHEE?BEEC>FHII@GEHIIIFIGH@GGDEEGHIIIG>CGBFHAFHGIGCHIACHDDEFFFF@CAEC?>CC
@2FF
CAGTGACCTGAAGGAGGTGCCGCGGAAAAACATCACCCTCATTCGGGGTCTGGGCCATGGCGCCTTTGGGGAGGTGTATGAAGGCCAGGTGTCCGGAATGC
+
BCCDFFFFHHGHHJJJJGHIIJJJJJJJIIJJJIJJJIJJJJJJJJHFFDEEEEDDDDDDDDDDDDDDCDD<@D2?@@DDDEDDDDDDD>ACCABDBBDCC
@2FG
CTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACT
+
CCCFFFFFHHHHHIJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJIJIJJJIJJJJHHHFFFFFEEEEDDBDDDDDDDDDDACDDDDDDDEEDDDDDDDD
@2FH
GAAAACACGACATGTGAATATCCTACTCTTCATGGGCTATTCCACAAAGCCACAACTGGCTATTGTTACCCAGTGGTGTGAGGGCTCCAGCTTGTATCACC
+
CC@FFFFFGHHHHJFHIJJJJJGJJGIIJJJJJJJIIIJJIGIIIJJJJIGIIJIIJJIJIJJIJJGHFHHFF@CE@=;?CCDDDDDDDDDDDCBDDEEDD
@2FI
CCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGT
+
C@CFFFFFHGHHHJJJJJJJIIIIJIJJIIJJJJJJIJJJJIJJJJJJIJEIHAEHHHFFFFFFEEEEEDCDDCADDDDDDDDDDDDDDDDDDDDCCBDDC
@2FJ
CACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGAT
+
??<?:AD:ADBDDE@8<8CEEEBEI@ECDCDCDDDDB@D99DDCCDEEIE@@A@C37;=ACDC>?A@@D2>=AAA>=>>>>A>AAAAA??>??>><AA>9(
@2FK
CAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGG
+
@@@?DBDBFFBH?CEGDFEEFFBCGC?9<CC)1::DDDG>AFGABG99BG;1DEGCGFAFC@8)))).6===A;?@@AAA?@8?B=@3>A>ACC(:>3:>@
@2FL
CAACCACCCCTCAACCCCTGTTTTCCCCTGCCTTCCTTGCAGAGGCCATGGAGGACGAGGAGAGACAGAAGAAGCTGGAGGCCGGCAAAGCCAAGCTTGCC
+
@?@BABDDDFD?DE;AFD?CHHGEBGIAB?BDBFIDDABGABHFEGIBA>@AHC@CAAB8<5=ABCCC>CCCC::A>9<982<99>BBB9913?224:9AC
@2FM
GGAGATGTTCTTACTGGAGACTCAGGTGGAGTCATGCTTATATGGAGCAAAACTACTGTAGAGCCCACACCTGGGAAAGGACCTAAAGGTGTATATCAAAT
+
@@@FDBDEHFHHGJIEGIJIIIJIIIHHIGECFGHIGGIGHJFIIEGGHIHIJJJJJJIGGGIIJJIIIGIHHHGAEEDFBBDEDDDDD-;:AFDFEEDDD
@2FN
GGAAAAGAAAAAAGAAAAGCACAAAAGGAAAGAGGAAGTGGAAGAGAATAAAAAAAGCAAAGCCAAGGAACCTCCTCCTAAAAAGACGAAGAAAAATAAT
+
?@@D;ABDAHFHDHEHGIGEH@FEHGCGIIIG9DFGCE?DG??D8BGECCHIIC<<BDE>C@@@CC@(=>BB<CBC?>CACAC>9?C>>5?@CC?BBCCE
@2FO
GGTGGTCGTACAAACTGCATCAGGAGATATGCAAACATATCAGATCCGAACTACACCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATGACATCTCCTG
+
B@=DDDFDFHHGHJJIJIGJJJJIIJIIIJIJJJJJIIJJJJJJIJJIIIJGJIJJJJIJIJIJJHHHHHHFFFFFFEDEDDDCDDCBCDDDDDDDDDDDD
@2FP
TAATTACATGCGGTAAATCTCATATTTTCTTCTGGACCTGGAGCGGCAATTCACTAACAAGAAAACAGGGAATTTTTGGGAAATATGAAAAGCCAAAATTT
+
CCCDDFDFHFHHFIIIGGIJJGIJJJIHGHGIGIGIHIIFIFGHGF@AEHGHGGIIGGGEFFHFF@DDCBBCDACDC?BBBCB:ADA>CDDDDDDDDDDDC
@2FQ
GTGAAGTTGGTATGGGGGGAGAACACGGCAGGGGAGAAGTAGAGCGTGGGGGAGGGGAGGAGTGGGGGGAGGAAGAAGGAGGGGGAGGAATAGGTGTGG
+
0(0(2:)).)2))2).(()&)&+(+()0&&)&&))&&((((+3/(&&&&))&&)&&&&&&((+((25&&&)0(262/((((&&)&&&&((((++++((2
@2FR
CAGCAATCAGGTGGTCGTACAAACTGCATCAGGAGATATGCAAACATATCAGATCCGAACTACACCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATG
+
CCCFFFFFHFHHAGHHIIIFIHEHEDHIIJIBFGGGIIJEICGCGIF@HIII@DHGDFGHIGEEHHGGGHFFBCCCDECECCCDDDDDBBCD:@CCDD>@
@2FS
CACTCATCAACAGCAGCTTGAAGAACAAGACCACTTATTAGAAGATTATCAGAAAAAGAAAGAAGACTTCACAATGCAAATTAGTTTCTTGCAAGAGAAA
+
CCCFFFFFHHHGHJJHIIJJJJHEHIJGHIJGGGJJIIIGIJJIIIIIHJGHGJIJIIIIIGIJGIJJJJDHFEHHHFFFFFFEEEEEEECCDDDDDDDD
@2FT
CAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATAT
+
CCCFFFFFHHHHHIIJJGHIIJJJJJJJJJIJJJJIIJJJJHIJJJJJIJJJJIJJJJJJJJJIHHHHFFFFFFEEEDEDDDDDDDDDDDDDCDEDEED
@2FU
GAGGCCGATGCGTAACGCACACTTGTTCCCCGCAAGTCAGAGGAGCAACGGCTCTCGCGCCGACCCCCCAGGGCGAGAAGCCCGGAGCGGAGGGCAACTCC
+
++++++)))02)2<2<@)@)1))10:**0*0)<'7/))//=)-6(6()(',','(-'(',')&)55(&))((&+&&)&&(+((&0)&&&)&&)&&((+++(
@2FV
TGAAAAACAGAGAAGCTGCTCGAGAATGTCGCAGAAAGAAGAAAGAATATGTGAAATGCCTGGAAAACCGAGTTGCAGTCCTGGAAAATCAAAATAAAACT
+
CCBFFFFFHHHHHJJJJJJJJJGIJJJIIJJJJJGIJIIJJJJJJJJIJJJHIJJJIJIJJJJHHHHHFFDDCDDCDDCCDDDDDDDDDDDDDDDDDDDDD
@2FW
GGAGTGGCCTTCTGTGGACGAATCAGATTCCTCTCCAGCACCGACTTTAAGAGGCGAGCCGGGGGGTCAGGGTCCCAGATGCACAGGAGGAGAAGCAGG
+
@CCFFFFFHHHHHIFHIIJJJJIJJIIIIJJJJJJJJJIJJJJIIIJJIJJJIJJHFFDDDDDDDD>BDDDD?CDDDDDDDDDDDDDBDDBDDDDDDDD
@2FX
GTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTAT
+
@@@FFFFEFHHGFHGIIJJJJIIGGIJJIJJIGGDHIJIIEGHIGJJJIGEHIJJIHHHCEFFFFCCEEEDDDDCCCCDC@CDBBDBBBCDDCCDEDDCDD
@2FY
AGAAATACTTATAGAGGAAAATGAGGACCTCAAACAACAATGTATTCAGCTAAATGAAGAGATTGAAAAGCAAAGGAACACTTTTTCATTTGCTGAAAAA
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHIIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHGFFFFFFEEEEEEEDDDDDDDD
@2FZ
ATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCA
+
@@@DDDBBHHHHH@@FGAFGIIAFCH@CFHGCHHBH@FFGIGCADD9BF;BBGCHGHGEGFGGCGEEBEECCCB;;;CCCCCBBCBC<5:AACDCCC:AC
@2G0
CAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGAC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHHHFFFDDDDDDDDDEDDDDDDDDDDDDD
@2G1
GGATACCTGTCTCCAGATCTCAGTAAGGTACGGAGTAACTGTCCAAAAGCCATGAAGAGATTAATGGCAGAGTGCCTCAAAAAGAAAAGAGATGAGAGACC
+
CCCFFFFFHHHHHIJJJJJJJIJHJJJJAFHGIIGCGGIJJJJJHIJIIHIGIIGIIIGHIJIJHIJGGIIG=EEHHFFFFFBAAEDDDDDDCDCDCDDDD
@2G2
GACAAGCCAACCTCAAGCAGAGGGACCTGATGAGGAAGTCTCGGAACGTGCTGACCACATGGCCTAAAAACTTAGCCTCGCACCAGGCGAGCATCCCCTCC
+
;;(8=..()<(-))))29(.)(((-(()2)):99).0(003))(0(.'9(35)))...().)())).)6.3:.((-:(47/'869(+(&)&))(8+2++)(
@2G3
CCTATGTTGACCTTGATCGTCAGCTGAAGAAAACTACAGAGGAACTAAATGAAGCTTTGTCAGCAAAGGAAGAAATTGCTCAAAGATGCCATGAACTGGAT
+
@CCFFFFFHGFHAHFHIIIGHHH>CCHCHIIEHECGCHGIGGEGIIGIH9FEGHFC@@<8)BCFGHGGIACGECEEEB3@DFDCEECCCCCCCCCCCCA?3
@2G4
TGTACCGGAAGTTCACTACAGAGAGTGATGTATGGAGCTTCGGGGTGATCCTCTGGGAGATCTTCACCTATGGAAAGCAGCCATGGTTCCAACTCTCAAAC
+
@C@DFFFFHHHHHIJIJJJJJIJHICEFIIICIIIJJJIJHHIJJAHIIJIJJJIJHHGEFFFFFFEEEEEEDDDDDDCDDDDDDDDDDDEDDDDDDDDDD
@2G5
AAATGAATGGCAAAGCTCTCCTGCTGCTGACCAAAGAGGACTTTCGCTATCGATCTCCTCATTCAGGTGATGTGCTCTATGAACTCCTTCAGCATATTCTG
+
CCCFFFFFHHHGHJJJJIJJJJIJJJJJJJJJJIJIHHIGHIJJIIJJIIJJJJJIIJJIJJJGIJH7AEEHCDFFFFFEEEEEEEDDDDDDDDDDDEEEE
@2G6
CAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGC
+
????DDADBDB:C:CEEE:3@?9ACC@E>@:CD?DEEE<@<<BDDAD;D?B<BCEEACDEIEC=CDCDD>7?=;@@AAAAAA>>AAAA:A>AAAA>ADA>
@2G7
AGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGC
+
@@?BDD>BBA8?FDFGG3CC@HHGIG@E@E@?FHECFEFHGGHDFD;=CGCB4@F3@=DEH=EEHH=;BCDD>ACDCCC>;;;=C>>@CB?<?>@CBBBB
@2G8
CTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCT
+
CCCFFFFFHHHHHJJJJIJJJIJJIJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJIJJJJJIJJHHHHHFFDDDDDDEEEDDEDEDDDDDDDDDDDDD
@2G9
TGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGC
+
CCCFFFFFHHHHHJJJJJJJIJJJJJIJJIIIJJJJJJJJJJJJIIJJJJJIIIJJJJJJJHIJIHHHHHHFFFFFFEEEEACCDDDDDDDDDDDDDDDD
@2GA
CTGGCCTGTTTTTCTGAATGCCCCAACGTCGGGCCACCTCTTCAGGCTCAATCAGTTTAAATTCCATGCCTCGACCAGTCCAGGCAATAAAATGAGAATTT
+
@CCFFFFFHHHHHIJJJJJIJIJJJJJJIJIJJIJJJJJIJJJJJJJJJJJJJJJHHHHHGHFFFFFFFECDC>BDDDCDDCCDDDDCDDDDEDDDDDDDD
@2GB
CTTCACAATGCAAATTAGTTTCTTGCAAGAGAAAATTAAAGTATATGAAATGGAACAAGATAAAAAAGTAGAAAACTCAAATAAAGAAGAAATACAGGAA
+
CCCFFFFFHHHHHJJJJJEIIIJJJJJJJJJJJJIJJJJJJCGGHJJJJJJIJJJJJIJIJJJJJJJJDHEIJIHHHHHFFDFFFDDCCEDDDDDDDDDD
@2GC
ATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCC
+
CC@FFFFFFHCDFHIIIIIIIJJJJIIIIJJIJGIIGIIIIJIJJJJGGHFHIIIIJIIIJIIJIJIJHFGHHHFFEFFFCEEDCCCDCDDCDDCDDDDDD
@2GD
GCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGG
+
??;;AB>AA<?DAEEB>@FDGH>AF?9AFEH@BF>@1)?77BB.==@C665C6A=;A;;7;C;6>>;6>@CC@>A:>>35:;@@>AC>8<@?::(:C32<
@2GE
CAACTTGAAGCAGAGAATAGCATTCTTAAAGATGAAAAGAAAACCCTTGAAGACATGTTGAAAATACATACTCCTGTTAGCCAAGAAGAAAGATTGATTTT
+
B@CFFDFDFHHFHJJGIGIGIHIIHGIDHDHDHHJIIIJJJIJJGIJJJHEGIIJJIEGHIIIIGII>GHIIJJJEHEHEHFFFF@ACACCCCDDDCCDDC
@2GF
CCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTC
+
@CCFDFFFHHHHGGGJIJGHIHIJIIJIEDGG?FADHIGIGII=@FGIGIJJJJJIFFG?DFFFFDEEECCCCDCBBDDDDDD@?@ABACDDCDCCCCD
@2GG
CACAAAAATAATAGAAGAAGAAAAGAAAACTCTTGAGCTAAAGGATAAATTAACAACTGCTGATAAATTACTAGGAGAATTACAAGAACAGATTGTGCAA
+
CCCFFFFFHHHHHJIJJJJJJJJJJJJIJJJIJJJJJIJJJJJIJIJJJJJJJJJJJJJJJJJIJJJJIJIIIIJHHHHHFFFFFFEEDEEDDDDCCDED
@2GH
CTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGGAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTT
+
?@<DDBD?>FBDFGGGH?A9FHCGG9AE<CGEF94EEBEEICG@B)9?FH9FB:<BFHI';?==CCD@;C;(;8;;>@B?BBBB;98<+4>>CCC?<9>BB
@2GI
CCTCCTCTGATGATTAAACAGGAACCCAGAGATTTTGCATATGACTCAGAAGTGCCTAGCTGCCACTCCATTTATATGAGGCAAGAAGGCTTCCTGGCTC
+
@@<DDFDFFHFHHGBFFHFIHIBFFCFEAC@G?E?*1CBDH@FFHDD9DHIIDH<DDGHBAFCGHI;=;DAH:==CHEHEHBF65@A>;A@=CC>CA?5>
@2GJ
AGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACC
+
@@@DDDFFHGGHG8FFGE@FGIIIEHHDCFCGEHEHIGGCHGHHDHGB@EAHEH=BDBFCACEECCCCCCCB:@BDDDDBA@BCDDCCBCCCCC:AAA?AB
@2GK
GTTTATTTCATTGCATCAGTAGTAGTACTATTTAATTATGAGGAGAGAACTCAGCGACACTACCTGGGCCATACAGACTGTGTGAAATGCCTTGCTATAC
+
@??BD?DDDHBDFGHBFEFIBHEBEB?BADEAFB??<B@FBEEBB)?)?D@FBFEB:FA;@@FC>EH;@EEEEA?C7;;>@C;@ED>@>CC@A@>>CDCC
@2GL
GCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGT
+
:8==++:B=C<D:<:A<A?:C,<3C3A<@E@AE;?>)?C49?D)3)012(?D;CDIBC;8@74.=CAA5A/4?@A6..;;>>>A;>((:9<<9<3:+:A:A
@2GM
CCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTT
+
CCCFFFF@FHGGHIJJJJHHIJJJJIIGIJJJJJJJIJJJJJJJIIJJJJJJIHIJJJJJJGIHHHHHFFFFFEDEDDEEDDDDDEDDDDDDDCDDCDDDD
@2GN
ACATATCAGATCCGAACTACACCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATGACATCTCCTGTGACTCTCACCTCTCAGACAACTAAGACAGATG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJIIJJJJJJIJJJJJJJJJJHIJFGIJJIJJJJJJJJJIJJJJHHHHHFFFFFEEEEEEDDDDDDDDDDDD
@2GO
GAAAAATAATTCTGTGGGATCATGATCTGAATCCTGAAAGAGAAATAGAGTTTAGTGCTTCAAGGGCCAGGCTGCCAGGCCATGTTGCAGCTGACCACCC
+
B@CFFFFFGHHHFIFGIJJFIJIIJGJJJJGIGGEHIGGICEHEGCHGHGIGIGGBFGIIHIIGHIIJIIJIJHHFHDEB?BCCCCCCCDDDDDCDDB?B
@2GP
GTGAAAATGTTGAATGTGACAGCACCTACACCTCAGCAGTTACAAGCCTTCAAAAATGAAGTAGGAGTACTCAGGAAAACACGACATGTGAATATCCTACT
+
B@@FFFFFHHHFFIJJHIIIIJJJIJJIJIJIJJJHIIJJGIIIJFHIJIJJJJJJJIJJIFHGIJJFHIIJJJJHHHGFFFFDCDDDCCDEEEEEDDDDD
@2GQ
GGCCCTCCAACCCCCCCACACCATCCAGCACGCCAGTGTCCCCACTGCATCATGCATCTCCAAACTCAACTCATACACCGAAACCTGACCGGGCCTTCCC
+
?<@A?;DDFHHAHIGGGFFHHHDFE@@BGGEAAFE87@7CEEEEEDCEBCCA@CCCECAACCACBCCCC?@CA@:ACCC5@BBBBCB?CCB7@B9@CCCC
@2GR
GCAGTTCAGAGGTAAATGGTTGCAGTTTTGTGATGAGAACAGGAAAGCCTACAAATTTATTAAGGGAAGAAGAATTTGGTGTTGATGATTCTTATTCTGA
+
?@@DDDFDB<FDCBHIGJICIGIIGJIJI@+ACD@BEHIIGGIHGJCAFGIGGIHIIEADAECGIDI@D@D@EC>CEHH2;?AA@@AEEF@CCCDC>CDE
@2GS
TATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGG
+
@C@BDDFDABDHBHEHGGIIGHHIIGCGIIGFHGIBHGGGGHIIIIIIIC@DGIGII<EEIGIGA>CH;ABDDFFFE==B@BC>>CBDDDCDDDCDDCCCC
@2GT
CTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTT
+
CC@FFEFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJIJJIJJJIJGIJIGHHCHHFFFFFFCDDDBBDDDDDDDDDCDDDDEDDD>@<@
@2GU
ATTGGGAGATTCCTGATGGGCAGATTACAGTGGGACAAAGAATTGGATCTGGATCATTTGGAACAGTCTACAAGGGAAAGTGGCATGGTGATGTGGCAGTG
+
?<?DBD;D?;CC,<<E<B<3AFD8CE??9?:?;C:DDIIIAADDEED>B<BDDECBCB4@AC>;C@7;A@;?CCA@(;@A3;@?=:>>-;A,5(,:2<<35
@2GV
GTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACA
+
CCCFFFFFHHHHHJJJJJJJJIJIGGGHDDGIJJIJGIIJGIIIGGIJHG8EHFHGGIJJJJIJJJJHGFHHFFFBEEDCDDDDDDDDDDCACDDCDDD
@2GW
CGGAGGAAGAGGACAAGTGCAAGCCTATGTCCTATGAGGAGAAGCGGCAGCTCAGCTTGGACATCAACAAGCTCCCCGGCGAGAAGCTGGGCCGCGTGGTG
+
@@@DDDDDHFHDHEGII<EEHHIGCAGCHDGGGECG@FCFGEGGEHIBFE5@EHE>ACDE;;?@>@C9@BC?>@CBBBB<B5<59A>@CCB<?B>B<BB2<
@2GX
CTTCTTTGGAGCCGCATCACAATACTGGACCTCCCCCACGGGGGGAATCTACCCCAACCCCAACGTCCCCCGCCATCCTAACACCCACGTGCCTTCACACT
+
CC@FFFFFGBHGHGHJIIJIGIIJJIJIIIJJJIJJJGIIJIJFD@BDDDDDDDDDDDDDDBDDBABBDDDBDDDDCDDDDDDDDDDBD2?BDDDDDDCCD
@2GY
AAAAAAAAGAGGAATCTCATTCTAATGATCAAAGTCCACAAATTCGAGCATCACCTTCTCCCCAGCCCTCTTCACAACCTCTCCAAAT
+
?@@BDFFAHFHFFIIJGDGGHGGGIIJIIDEGIGBDGGIIGAHHIIIDIIIJIJJIJECACADFFEDDCDDDDECCC?BCCACAACCC
@2GZ
CTGAAGAATTCCAACCCCGACGAGATTGAAATCGACTTTGAGACCCTGAAGCCGTCCACACTGCGTGAGCTGGAGCGCTATGTCACCTCCTGTTTGCGGA
+
CC@DFBBBFHFFHGIIIIGHGGGHHIGIIIGGIGIIIIGIIIGGIGDEGHGHHEFFFAEAB?ACB6?BBCCCCABCBC?<BACCDCCCBCCCCCCCCBBB
@2H0
CTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGAC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJHHHHHHFFFFDDBDDDDDDDDDDDDDCDDDDDDDDDDDDDD
@2H1
GGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTT
+
@CCFFFFFHFFHGGJIIIDHHIGIJGDHIIIJJGIGJJJJ>GIIICGGIGIIEIJJGFHHIJJCEGGGHCAEDEDFDFCCDBDD=BBD=CCCDCCDCCDD
@2H2
GTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJHIJJJJJJJHIIJJIJIJHHHHHFFFFFFFEEEEEEDDDDDDDCDDDDDDDDDD
@2H3
AGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACC
+
@@@FFFFFDDFHDHIJJJJJGGIGIGGIGIJJJIIJIIEAHIIJIIGGGIIJHHGHHFFEBECB>CEEDCB@AB@DDCCDBDDDACCCB@B>ACCCAACCC
@2H4
TTCTGGATGACCCTTCAAATTCTCATTTTATTGCCTGGACTGGTCGAGGCATGGAATTTAAACTGATTGAGCCTGAAGAGGTGGCCCGACGTTGGGGCATT
+
@@@FFFFFGHHGGJIIIGEIJ9HHIIIGGJGHIHDHHGIHEIIHJHFHIFIIIGIJJJCFGIGIIJIG<CCCEDB@@CABC;?BBDBDBBBBBDDDDDDDD
@2H5
GGCAGTACTCAGCAAGGTACAACTATTCTTCAGTATGCACAGACCTCTGATGGACAGCAGATACTTGTGCCCAGCAATCAGGTGGTCGTACAAACTGCATC
+
CCCFFFFFHHHHHJJJJEIIIJJJJJJJJIJJJIIJJJJJJIJJJJJJJJJJJIJJJJJIIJJJJJJGGIIJJJIHHHHHHF?BF>CDDDDDDDDDDDDDD
@2H6
TCAAAGCCGTGCACGAGCAGCTTGCAGCCCTCTCTCAGCCCCAGCAGAACAAACCAAAGAAAAAGGAGAAAGACAAGAAGGAAAAGAAAAAAGAAAAGCAC
+
?@@FFBFBHCFAFBAGD6DEFFHICGGCCGHHCFEGGDEGBF;FCGIFGIIGGGFHFEDDEFCABA??A?CCC?CC9ACC?BCCC<8ACCBBBCBCCCBCA
@2H7
GTCTCTGTCTCCCCGCCTGAAGAGCACGCCATGCCCATTGGGAGAATAGCAGATGTGCAGCACATTAAGAGGAGAGACATCGTGCTGAAGCGAGAACTGGG
+
::14AD?DDCC???@EE1AAAFF;;E?DC8:::99?*99DEI(-7B).88)/@DE)7A@))=ADA>.?7@@;(5(;?==A3=(<58:>A:3;<5>>>>:>>
@2H8
GGTTAGTAGGACGAGGGCGATGAAGGCACCACATGAAGAATGCGATGAAGTGCAGGATCAATGGTTGCTGTAAGGGCAGTAAGGGTAGAATTGAGCATGAT
+
-(((((2)2)))((-((-:(<4))))(((-3.6)0)))))))/-((-..).;8)30=;06(((..69;5(((((((((,(,((((((+((+(+((++2(((
@2H9
CTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTC
+
@@CDFDDFHHGDHJJGHIGHJIJIIGIIIGGIEIGIIIGGGIIJIJJJJJIIJFGIJIIJGIHHIGHHHFFDDDCDDDACDDDDBACAC?@C>CCDDDDCA
@2HA
ACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGTCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGC
+
;@@DDD8@FDDBFIEBHEFIGFFC<?AECFFGEIIE?B??D??9??B@BBFBC888BFHIIA;5=EH;=DEEDE>AACBC;;5><B?B;C>9834?9A+94
@2HB
CTCAAGGATATGCACAGACCACCCAGCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACT
+
CCCFFFFFHHHHHJJJJJJJJJJJJIJIJIJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJIHHHFFFFFEDDEEEEDDDEDDDDDDDDDDDDDDDDD
@2HC
CGATGCCAAGGGAAGGACGTCCTATGTACCAACGCCAGATGTCTGAGCCAAACATCCCCTTCCCACCACAAGGCTTTAAGCAGGAGTACCACGACCCAGTG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJIJJJIJJJJJJJJJHHHHFFFFFDDDDDDDDDDDDDDDDDDDD?CDDDDDDDDDDDCD
@2HD
TGGGAACACTCTGCCATCCCCCAGCAGCTGGGACCTGCAGCCAGAACTTGCAGCTCCACAGGGAACTCCGGGACCCTTGGGTGTGGAGAGGAGAGGGTCTG
+
?@@A?BDEGGFHHIGIGHGHGHEHGDEEE?CF@EHFHHGHIJIJGGHIJGHHHIAFHIE=@@=HHFFFDDDBDBDB<ACD?5508?383<?1<28<B83<C
@2HE
CAACAAGCTCCCCGGCGAGAAGCTGGGCCGCGTGGTGCACATCATCCAGTCACGGGAGCCCTCCCTGAAGAATTCCAACCCCGACGAGATTGAAATCGACT
+
?<?:DBDBDDDDDEEED):6@@DCED?DC'@8:??.;>AA;>A>AAA>>,::>8?:<6-8<3<=>?A<AAAAAA:>BAA?>;?;>;;9>2>A:>>::<(5<
@2HF
CTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACT
+
@@CFFDDEBFDHFBFHJIIIIIHIIIGIFGJJJJJGGGIGJJJGIIF=GGEHDCGGGDEFECB?CCCECDBBBDA?BDDDDDACCDDCCCCCDDDDD@?AA
@2HG
GGGAAGGCTCTTCAGGAGCCATGTGGGGAGATGACAGAGGTACCCCCATGGCTCAGAGTTATGATCAGAATCCTTCCCCTAGAGCAGCTGGGGGGAGGGAC
+
<@@DABD?DHD?B<G@A:AA?ABACHIE??00000??*?G*????=6;7=@>7=7=CA.7=?=7@D>@:>>;C@C@>=C?5955(:95559+5&0))00&2
@2HH
CCTTGGCACAACAACTGCAGCAAAGACTGGTTCTCACTCACCGGGCGAGGGCGGGTCTCTCGGAGGAAGGACTTGAGGTCTCCCCCCGCCATGAGCTCC
+
@@CFFFFFHHHHHGGHIIHJJJIJJIIJIJJIJIJJIIJJIJJJJJJJJHFFDDDBDDDDDDDBDDBDDDDDDDDDDDCDDDDDDDDDDDBDDDDDDDD
@2HI
GGAGAAGCGGCAGCTCAGCTTGGACATCAACAAGCTCCCCGGCGAGAAGCTGGGCCGCGTGGTGCACATCATCCAGTCACGGGAGCCCTCCCTGAAGAATT
+
B?@DDFDDHGHHHJJJJIIJJJJJJIJGIIHIGGIIIJIJIJJEFDCCDDCDD=ABBBD<BD8@CCCCCDDCDCDC4:@C<>BBDBDDCBDDDDDDDDDDC
@2HJ
ACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCA
+
@@CFFDFDFHHGHHJBGHHCHGGIHAGG@IHGIDGHICEIGIGIJIJGEGB?BFBGGHFIIJIGFHEEEFFFFDEEDDBDDD?BDDCCCDDCDDCCCDB
@2HK
AAAACGACCATCACCAGCTGAAAAGTCACATAATTCTTGGGAAAATTCAGATGATAGCCGTAATAAATTGTCGAAAATACCTTCAACACCCAAATTAATAC
+
?@?DDD6DF<FFF@GIBBBBBGB@??EHI@H<::?@D9BFHFGGIDEAFAHIGI:FB;FEGBEEHHHE;?7?9BAC?CCCCC>C@@C>BBB@?@::@>CDC
@2HL
CCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHHHFFFFDDEEDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDD>B
@2HM
CCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGT
+
@@@DFBDEHHHHHEHGIIII?FHIIIIIIGHGGGIIIIIIIIIGEDEGIIIIG=AEFFFCDBD@CEEEECCBB;@CCCCCBBBBBACCB@?CCCCCCBBB>
@2HN
AAGGCTTTAAGCAGGAGTACCACGACCCAGTGTATGAACACAACACCATGGTTGGCAGTGCGGCCAGCCAAAGCTTTCCCCCTCCTCTGATGATTAAAC
+
C@@DFFFFHGHGHIJIIGHIJIJJJJJJJJGIIIJFIIJIJJJJJJJJJJIFGIGIJJCHHGFDDDDDDDDDDDDDDCDDCDDDDDDDDDEDEEEDDDD
@2HO
GCAGTCTCTTGTAAATTCAAAGTCAGAAGAAATGACTCTTCAAATCAATGAACTTCAAAAAGAAATTGAAATACTCAGACAAGAAGAAAAAGAAAAGGGT
+
CCCFFFFFHHHHHIIJJJJJIIHGJIJJIJJIJIJJJJJJIJJJJJJJJIJJIJIJJIJJJJJJIJIJIJJJJJJJJJJJHGHHF@DFFEEDDDDDCBDA
@2HP
CTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGAC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJIIJJJJJJJHIJJJJJJJJJJJJJJIGHHHHFFFFECDDDDBDDDDCDCEDEEEEEDDD
@2HQ
CAGGAAACATGGCTTGCAGAAGAAGTGCCTAGCTGCCACTCCATTTATATGAGGCAAGAAGGCTTCCTGGCTCATCCCAGCAGAACAGAAGGCTGTATGTT
+
CCCFFFFFHHHGHJJJJIJJJJJJJBHGIJIJIJIJJJJIGIGHJJJIJJJGIJJGJJIJIJJJJIJIIHHGHHFFFFFEEEECDDDCDDDDBCBBDDECC
@2HR
GCCCATCAACCTCTCTCATCGGGAAGACCTGGCTTACATGAACCACATCATGGTCTCTGTCTCCCCGCCTGAAGAGCACGCCATGCCCATTGGGAGAAT
+
@@@DDFDFGHGHHJJJJIJJJIIJJIJJGIJJJJGIJJJJIJJJJEIJJJJJJFGHIIJHGIIJJJHFFDDEEEDDCDDDDDDDCDDDDDCDDBBDDDD
@2HS
CCCGCACAGCCCACTGTGGTCCCCACTGTCTACGAGGTGCATCCGGCTCAGTACTACCCGTCCCCCGTGCCCCAGTACGCCCCGGGGGTCCTGACGCAGG
+
@@@D?1ADFFFDBEFI?AG+AEF9BGADGF>DDBG8F@8?3?4)7<44@;=@77?A=A.=95=?@BBB?/9:@BB4::<55<5>&59@)5?AA39599>>
@2HT
CCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTA
+
C@@FFFD>?FFHFHIBBHEGBFFGIE>CBDBDDDHDDE@FDFGBCFFFFGIG9CHDEHA?ACCE?;?BCCCCBB<A@@A<ABCCCCCCCCCCCCC?CCCC
@2HU
GGAAAACCGAGTTGCAGTCCTGGAAAATCAAAATAAAACTCTAATAGAAGAGTTAAAAACTTTGAAGGATCTTTATTCCAATAAAAGTGTTTGATTCCTA
+
@@;B=DDDFDDDD9CDFDH>>HIIGFGIFIC@HHGIEIIEF?<@GB@GDEHIFFIIGIIBHIIE>@ECAHFHFHCEEEDEBDDCCAC@CAC?C>CCDCC:
@2HV
CTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJIJJJJJJJJJHIIJHHHHFFFFFFEDEEEEEDDDDDDBDDDDDDDDDDD
@2HW
CTCAAATAAAGAAGAAATACAGGAAAAGGAGACAATCATTGAAGAATTAAACACAAAAATAATAGAAGAAGAAAAGAAAACTCTTGAGCTAAAGGATAAAT
+
CCCFFFFFHHGHHJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJHIJJJJJJJJJIJJJJJJIJHHHHHFFFFEEEEDEDDDDDDDDDDDDDDE
@2HX
CCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCC
+
CCCFFFFD?FDHHEIJDGIIJIIGBHIJJBEHBGIGDFICHGICHIGEGHIJJEGG;FIEGICHJEGEEEEE7@B@ACDC@CD>;=?CACD@BCBDDD@B<
@2HY
GACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTG
+
@?@BFFFDHFHHH>GGGEGDIGEH?FHIIIHGGIIIDHGIJJFGCGIG@FFEGIJ;DCC@CHHCCD@?CCCCCEE?;@CDBDDDDBDDCDDDACBBBDD?B
@2HZ
CCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCG
+
CCCFFFFFHHHHHJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJIIJJIJIIHHHFFFFFEEDEDDDDDDDDDDDDDDDDDDDDD
@2I0
CTCCGCTATTACTATGAGAAAGGAATTATGCAAAAGGTGGCTGGAGAGAGATATGTCTACAAGTTTGTGTGTGATCCAGAAGCCCTTTTCTCCATGGCCTT
+
CCCFFFFFHHHHGJJJJJJJJJJHJJJJJJJJIJIJIHHIJJJIGHGIJIHJJJJIGIIGFIIJJJJIHHF;BDFFFEEEEEEDDDDDDDDDDDDCDDDDD
@2I1
CCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTT
+
CCCFFFFFGHFHHJJJJJJJIJJIIIGIJJJJJJJJJJJJIJJIIBHIIJJJJFHHGHHFFFFCDEECCCCDDDCDEDDDDDDDDDDDDDDCDDDBDD>B
@2I2
AACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJGHJJJJJJJJJJJJJJJJJJBGHIIJJJEIJJJJJJJHHHHHFFFFEEEEEEEDDDDCDDDDDDDDDDDDDD
@2I3
GGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATAT
+
8;@DADD=FHDFF@@B?CEFHGEHII<9EGEF?:FH?BFGGBBGDE=BCG@E?AA??A??BB@CBCBBBBB<@@B@CCCC>8::>
@2I4
TGTCAACATACGAGATGTTAAAGATGACTGAGGCCTCCAACTAAGGGTCAGCGAGGGAACCTGCCAACTTAATGGTCATTCTTATGACCCCCAAGAAGA
+
?+:1A;B+++2+<<?ECEB<4:<CC>EC4+*1:183)1??9?BD99)9*?DDAD6@''((().(6);,.(.55>(-(5;35>(;35(:>28))8883++
@2I5
GGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAAT
+
CCCFFFFFHHHHHJJJJJJJHIIJJJJIIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHFFFFFEEEEEDDDDDDDDDDDDDDDDDDDEDE
@2I6
GCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGT
+
<<@DDD?BFBFFD@EE;FAEE:@FCHGE>GC@<FC?D@FGBF<B<DHH?9BFBC=FB;@FCHG@=6=AAC<<A>BCACCCCC@CA@<9A<<+::::ACAC(
@2I7
AGCAGGAGGAGGAAGGGATGTATCCAGATCCAGGTCTCCTGAGCTACATCAATGAGCTGTGTTCTCAGAAGGTCTTTGTCTCCAAGGTGGAGGCTGTCATT
+
<@@DDBBDFHBDDGGBE=EFEDFBFEHCFDHEFE?GDFEGHDEFDHEEGIEDGGBF@CHCFCACECC@GCCE7?@C?DCECCA@CCB5>=ABBB@A?@CCD
@2I8
TTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACC
+
CCCFFFFFHHHFHJJIJJGHIHIIJGHIJJJEHCFGHEIJIJJHGGJGHIIIJBGGIJJJJIGIIIGHHHFFFFFEADCEDDDDCDCCDCCDDDDDDDDDB
@2I9
GGGAAGGACGTCCTATGTACCAACGCCAGATGTCTGAGCCAAACATCCCCTTCCCACCACAAGGCTTTAAGCAGGAGTACCACGACCCAGTGTATGAACAC
+
@@@ADFFDFHDDHIHGIGGIIHEHBGEGIGIHFGGGGGFHIIIEGGHIIGCHAHGGGBCCC?D<BACCECACDC?B?CCC>>C?=BDDDB:AC>B>CC>:9
@2IA
TGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTAT
+
CCCFFFFFHHHHHJJJJJJIJJJJJJIJJJJJJJJJJJJJJJJIIIJIJIJJJIJJJJIJJJHHHHHHHFFFFFFEEEEEEDDDDDDDDCDDDDDDDDDDD
@2IB
CGAGGATACCTGTCTCCAGATCTCAGTAAGGTACGGAGTAACTGTCCAAAAGCCATGAAGAGATTAATGGCAGAGTGCCTCAAAAAGAAAAGAGATGAG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJIJJJJHIIJJIJDGIJJJHIJJJJJJJJIJJIJJJJJJJJJJJJJHHFH;CEFFFEEEEDDDDDDDDDDDDDD
@2IC
CCTACACAGCCTGCTGAAGAAGCAGCACGAAAGAGAGAGGTCCGTCTAATGAAGAACAGGGAAGCAGCTCGAGAGTGTCGTAGAAAGAAGAAAGAATATGT
+
@@@FDDDEFFFDHGHIGGAHGGEHCEHGIHHGGBGF????DHFFFGGIFGE@HIIIGHGHHFHBE@CB;>AB@BB(55>?8AB<CCCC@?CCCCCBC@C@>
@2ID
CGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTT
+
C@CFD:DDHHHFHJIGIGIIJGIJGHGIIIGHEGHIFGGJJJJFIGHHCHGIIGJJIIGFEFFEFFDEEEDEEDDCD@CCDDDDD8<CACDACCDD4<CDD
@2IE
TACCTACTTAAGATTCATTTGGAGGCATGTCTAAATCTAGTAATTTATTAGAAGCTTATCCATCCCTATTACTTTTTTAAATGGCATTAGTTCTGTGTGCT
+
CCCFFFFFHHHHFHIIJJJIJJHIJJJJIIJJIJJJIGHIGGIIIJIIJJIIIGHIIIJIHJJIJJJJJJIIIJJJJHHHGGFFEEFECACECDCDDCBCD
@2IF
ATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATG
+
@@@DD;DDHHFHD??CBFHGE:<@@GGCHGGHIHBGEHGFHIIEEGGHGHIB=FHIIICFGHIIIIHFAHEE=;??AB??A@CCDCCC@AC>@CCCCCCC@
@2IG
CACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJIJIJJJJJJJJJJJJJJHHHHHHFFFFFEEEEEDDDDDDDDDDDDDDDD
@2IH
CTCAAGTCCTTCCTCCGAGAGACCCGCCCTCGCCCGAGCCAGCCCTCCTCCCTGGCCATGCTGGACCTTCTGCACGTGGCTCGGGACATTGCCTGTGGCTG
+
@@@DFFD?FBHHGIEHBG@A:AFHFGIIIAG@@A@@A8AEHEHH?CF?>CC?;@BBBCCCCCC@5?CCCCCCCCC?8<@>8>9@@9><::>:>@CC@C??B
@2II
GAAAAGTTCTGTCTTTGATGAAGACAAAACTTTTGTAGCAGAAACATTGGAAATGGGTGAGGTGGTTGAAAAGGATACAACAGAACTCATGGAAAAACTTG
+
CBCFFFFFHHHHHJJJJIIJJGJJJJJJJJJJJJJHHIJJJJJJJJJJJJIJJIJJJDHHIJE.5@FIJJJJHHHHFFFFFDEEEEEDDDDDDDDDDDDDD
@2IJ
GATTGAAGAGCTAAACAGAGAGCTGGAAGAAATGAGGGTTACCTATGGGACTGAAGGACTGCAGCAGTTACAAGAATTTGAAGCTGCCATTAAACAAAG
+
CCCFFFFFHHHHHJJJJJJJJJIIJJHJJJIHJJJJIJHIJJJJJJJJJJJJJIJJJJJJJJJ7BGIHFHHHHFFFFFFEEEEDDDCDDDDDDDDDDDD
@2IK
CATCAACCAAGAAGGAGAATATATTAAAATGTTTATGCGCGGTCGGCCAATTACCATGTTCATTCCTTCCGATGTTGACAACTATGATGACATCAGAACGG
+
CCCFFFFFGHHHHJJJJJJJJJJJJJJJJJJIIJJJJJJJJJJJJJJJJJHHHHHHHFFFFFF)6>CEEEDDDDDDDDDDDDDDDDDEDEDDDDDDDDDDD
@2IL
GTTCCTTGGCTTTGCTTTTTTTATTCTCTTCCACTTCCTCTTTCCTTTTGTGCTTTTCTTTTTTCTTTTCCTTCTTGTCTTTCTCCTTTTTCTTTGGTTTG
+
@@@DDFFFHGHHHJJJJJJIJJEHHGIHIIGJIGIJEHGJJJJGIIJJJIJJGIIJJGHIJJJHHHHHHEEEFCEECA@CCEDCDCDDDDDDDDDCCBDBB
@2IM
TGATGACATCAGAACGGAACTGCCTCCTGAGAAGCTCAAACTGGAGTGGGCATATGGTTATCGAGGAAAGGACTGTAGAGCTAATGTTTACCTTCTTCCG
+
CCCFFFFFHHHHHJJJIJJJJJJJJJIJJJJIJJJJJJJJJJJJHJBFHIJIIIIIIGGIIJJCEHFHFFFFFEDEEEEDDDDDDDFEEDDDDDDDDDDD
@2IN
GTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACT
+
C@@DFFFFHHFHHJIGHJIJJIJJJJJJJFHGHGHIIIIJJGIJJIJJIIIJIJGIJIJJJJJJIJJJHHHHFFFFEECDEEDDEEDDDDDDDDDDDDDDD
@2IO
GCAAGATGGACGGTTTCGCCGGCAGTCTCGATGATAGTATTTCTGCTGCAAGTACTTCTGATGTTCAAGATCGCCTGTCAGCTCTTGAGTCACGAGTTC
+
@@@DFFFFDHFDAIAGFDGEGIGHEHIIIGFGHFGGHIGIGGGIIIIIIGIHHHHHHDEDCDFECCCE@CACBBBB@CCCC@CACC:CCCCACBBC?@C
@2IP
TTCTTCATGAAGACCTCACAGTAAAAATAGGTGATTTTGGTCTAGCTACAGTGAAATCTCGATGGAGTGGGTCCCATCAGTTTGAACAGTTGTCTGGATCC
+
@@CFFFFFHHHHHJJJJJJJIJJJJJJJJJJAFGIJJJIJHIJIJIJJJJJFHIJJJJJJJIJJJIJDHIIGIHHHHHFFFFFFFEEEDEEDDDDDDCDDD
@2IQ
CTCAGATATATTTCTTCATGAAGACCTCACAGTAAAAATAGGTGATTTTGGTCTAGCTACAGTGAAATCTCGATGGAGTGGGTCCCATCAGTTTGAACAGT
+
@BCFFFFFHHGGGIJJJJIJJJHEJJGCGGHIIJIJJJIEHG?DBDGIJJIJEGHEEHIJIIJIJJIIJEGGEIGIIGHEHHFEFFAECECCCDA@CDCDD
@2IR
GAACGCCTCCCCGAGTGAGCTGCGAGACCTGCTGTCAGAGTTCAACGTCCTGAAGCAGGTCAACCACCCACATGTCATCAAATTGTATGGGGCCTGCAGCC
+
@@@DDFFFHHHHGJJGGIIIJGJIJJIJJJJIIIFH>FBFHIIEIJJHICGIHHHHFFF;?BECCBCDDDDDDCEDDDDCDDCDCDDDEDDDBDDDBCDC@
@2IS
GTGGGAGGACACACCATGCTCCCCATTCGCTGGATGCCTCCTGAAAGCATCATGTACCGGAAGTTCACTACAGAGAGTGATGTATGGAGCTTCGGGGTGAT
+
??@DFFFFDHHHHIIJJIJJJJJIIJJIJJJIIEGHEGGIIJJGJJJJIJJIIJIEIIJJGHFFDFFEECEEEED<B5;;;@@C@CCDBDDD@B@BD0<AA
@2IT
GAATACATGAAGCATGGAGACCTGAATAAGTTCCTCAGGGCCCATGGGCCAGATGCAATGATCCTTGTGGATGGACAGCCACGCCAGGCCAAGGGTGAGCT
+
CCCFFFFFHHHHHJJJJJIJJJJJJJJJJJIJJIJJJJJJIJJJJJJJJJJJJIJJJJIJIJJJJJJGHHHFHHFFFFDDDEBDDBBDDDDDDDD<@BDDD
@2IU
CTGATGTTCAAGATCGCCTGTCAGCTCTTGAGTCACGAGTTCAGCAACAAGAAGATGAAATCACTGTGCTAAAGGCGGCTTTGGCTGATGTTTTGAGGCGT
+
@@@FDDFFFDHFFGGIIJJGIJFIHGJIIHJJ@FHIE?CFGI@FGHIGGIDGGGIIIIGGHGDHGD=CEEHHEEEHDDBBBC@:CCDDDCDCDCB?@CB@>
@2IV
CTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAA
+
CC@FFFFFHHHHHHIIJIIHIJJIJIJIJJIIIFHIJJJIIJJJJJJIIJJJIJJIIFGIJJIHHEFDEDCCDDCDDDDDDDDDCCDDDEDDDCCDDDDD
@2IW
TCAAGAGCTGATGAGTAAAGAATCTCCTGTCTCTGCTGGAAATGATGCCTATGTTGACCTTGATCGTCAGCTGAAGAAAACTACAGAGGAACTAAATGA
+
?@@ABD??D?CF<GHFGFGHDG@FHIGGG?<E@BCFGGIIIEGGG>FGDHIGHGECGHIIIIICGHFHIGHIDHGGGHH>E:;CD@>@?@A?>@CC;>C
@2IX
GGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTAT
+
CCCFFFFFFHHGHIIIJJJJJIIIJJJJJJJJIIIJIIIIIJJJJJIGJIJIHHIEHIIJJJJJIJJJHGGHHCEFFECCCEDDDDDDDDDEDDDDCDDDD
@2IY
CCGCCTGATGCTGCAATGCTGGAAGCAGGAGCCGGACAAAAGGCCGGTGTTTGCGGACATCAGCAAAGACCTGGAGAAGATGATGGTTAAGAGGAGAGACT
+
@<@D?@A:?AF?F:EFBAGEH@<A:CGE?8?3CD:08@?B;?C=BFA':>E>;@DCC@;>>:@>:95:5<?:9@(<3<@94@34:A:@A4@:>?8?B?+<A
@2IZ
CAAAGTGCACGGCAAAAGATATGCTTACAAATTTGACTTCCACGGCATTGCCCAGGCTCTGCAGCCACATCCGACCGAGTCGTCCATGTACAAGTACCCTT
+
CC@DDDDFHDHA?EHHGB?HD?FHGHIGGIFHGDDDDGCDFHGEGIEHGIGICAFHAEHIHHHH@?BFDDCEBCBB@DD?A@?BDBDCCADDDCCC>@CAC
@2J0
TCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATG
+
@C@FFFFFHHHHHIJJGGJJIIJGIGIIIJJEHGIBHIGI@FHIIHIIIII=CHHHEEFFFFEEDDDDDDDCDCCCCDDDDCCBDDBDDDBDBBDDDDCDD
@2J1
GTAGAATTTATCCTCTGATTGTACCAATCTGAATAAGGATCCATGGTAAAAGCTGCCAATTCTAGCTTTAGAAATAACCTGGAAGAAATATATAGTTCAGC
+
;783@)=>@))))2))));))2)8:?=<1@))).))..)9=))13).)))))0)))(:9<))))/).)/=);>=8;))<).(().()))))).((.(.(((
@2J2
GCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGC
+
CCCFFFFFHHHGHIHJJJJJJJJJJJIFJIJJJJJJJJJJJJJIJIJJIJFHJJJIIJJJJJJJJHHHHHHFFFFFFEEEDEDDDDDDCDDDDDDDDDD
@2J3
CCTGTAACTCCTTTCCTCCTTTGCCGACGATGCCAAGGGAAGGACGTCCTATGTACCAACGCCAGATGTCTGAGCCAAACATCCCCTTCCCACCACAAGGC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIIJJJJJJJJHHHHHHFFFDDDDDDEDEDDDDDDDDDDDDDDDDDDDDDDDDDDDDDD
@2J4
CGGCAGTCTCGATGATAGTATTTCTGCTGCAAGTACTTCTGATGTTCAAGATCGCCTGTCAGCTCTTGAGTCACGAGTTCAGCAACAAGAAGATGAAATC
+
???1B:DDDDA3??@DEBF9EEC4A<FCE<FAE?::CEDDE>D<:BBDE9D94BD<??88=C<B>ADA7=)7@=;C:A=>@@ADA9;;???A>>5>>AAA
@2J5
CAACGAATGGAACAAGAAACACAAAGAAAGTTAGAACAACTCCGGGCAGAGCTGGATGAGATGTATGGGCAGCAGATAGTGCAAATGAAACAAGAATTAAT
+
CCCFFFFFGHHHHJJJJJJJJIJJJJIJIIGIJJJJJJJJIJJJIJJJFIJIIJJGIJHFHHHEFDFFFFEDDDDDCDDCDDDDDCDDDDDDDDDDDDDDD
@2J6
AGAGATTTTGCATATGACTCAGAAGTGCCTAGCTGCCACTCCATTTATATGAGGCAAGAAGGCTTCCTGGCTCATCCCAGCAGAACAGAAGGCTGTATGTT
+
=:8D:AD,2:ADCAE<4<ACF<:3<FB:<2<<+<:ECE?D;9:1:?DEAD@<D@DI;D??CDC=BD@==)6.=@;=CD?72?D@A(6.66-,=;;,5;A55
@2J7
CTGATCTGTCCAAGCCTAAAAACCTTGCTCCTTTACAAGAGAGTCAGGAGTCTTACACAACTGGGACTCCCAAAGCAACATCTTCTCACCAGGGCCTTGG
+
?@84=BA=ACFBHBGGB@A:?F?FCH<EB???GE<BGFCHG;DH<D<BB;FFGHIIGHDD;F;@=@>E=?A?76?7@;;>>6@>@A5;AB@?BB<?@>:3
@2J8
GGGAGACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTT
+
@@?DDDDD>?FACGBGIDFGD<DC?@GHI6?DBF;@FCEEHA@7@BHBE?D?BCBBCCCCBACCCA>CDCCCC<@CACCCC995>@BAABB<ACCC:@A>C
@2J9
GAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTG
+
CC@FFFFFHHFHGIIIJIJGIIIJIJJIGGDGHGIIIJIJGIIIJJIJBFGIJJJIIIHIJFEHGHHFEFCECEDDDDDCDDDDDDEDDDDDDDDBDDDCD
@2JA
CTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTAT
+
CCCFFFFFHHHHHJJJIJJJJJJJIJJJJIJJJJJJJJJJI;FHIJJIJJJHHFHHHFFFFFFEEEEDDDDCDDDDDDEDDDDDDDDDDDDDDDDDDDDDD
@2JB
CCAAAGTGCACGGCAAAAGATATGCTTACAAATTTGACTTCCACGGCATTGCCCAGGCTCTGCAGCCACATCCGACCGAGTCGTCCATGTACAAGTACCCT
+
CCCFFFDFHHHHGJJIIIGGGHIHIJJJJIJJJJIJGJJJJJJJGGJJIJFIJJJGHJCHHHFFHFFFFFEEEDDDDDDD?CBBBDDEDEEEEDCDDDDDD
@2JC
CAGCGTCCACTGCTGAAGACAGACATGGAACGTCACATCAACGAGGAGGACACAGTGCCTCTTTCTCACTTTGATGAGAGCATGGCCTACATGCCGGAAGG
+
@@@FDFDDHGFGGJGBHIIIGEIIIJIICDHIIGIEGJJJGFDHIGIIGGFHHIJAEHEHGEFFFFFFFFEAECCCECCCDDDDDBCDDDCCCCCB<@DBD
@2JD
GGAAGATTTAACGAATGGGGTTGTGATGGCCCAGGTTCTTCAAAAGATAGATCCTGCATATTTTGATGAAAATTGGCTAAACAGAATCAAAACTGAAGT
+
@@<DDDADFDH<DFBA?9FEHI<GB9*?<9?))0B?3?DDB9?B8?BDB@<F@C@@FHI@CDG@EDEF>CHC);BB<@@A>C@??@CCAACC(5:(,5;
@2JE
ATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCC
+
@@@FFDDDHHFHHIJJGIJJJIJJJIJIIJJJIJJJIIIIGGIJJI1@DFHIGIIIIIDEGGIIGIIHEEHHFHEFFFFFEEDEDDDDDBDDDDDCDCDCB
@2JF
GCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJIHIJJJJJJJJJJJJJJJJJJJJJJIIIHHHFFDDDDDDDDDDDDDDDDDDDCDDDDEDDD>
@2JG
CCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGAC
+
@@CFFFFFHHHHHJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJHHHHHFFFFFEEEDDDDDDDDDCDCEDEEEEEDDD
@2JH
GTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGAT
+
@@@FFFFDDHFHDGHIJJIHCGGIIJIDGHGI@GIIJJJJJJJJJIJGHIIJJJIJIJGIJJJJGHHEHDBDCDFEECCEEEDDDBDDD?BDBDCDDEDAD
@2JI
CACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATG
+
@@@DDDDDHFFFFFFHIEGGIIIIGGHJGIEHCHGIIGDFHJIEGIJGHIJIGGIJIIFHFED?A?@B?=CCACDBDDDACDDC?ABB??BBB?<B?CCA@
@2JJ
TGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGG
+
C@@FFFFFHHHHHJJJJJJJJJIJFHIJJJJJJIJJIJIJIJIIJJIJFHIIIJHHHHFFFDDEDEDDDDDDDDDDDDDDDCDDDEDCDDEDDEDDDDDDD
@2JK
TTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACC
+
CCCFFFFFHHHHFJJJJJJJJJJJIJIJJJJJJJJJJJJIGIIJJJJIJIIJJJJJIIHHHEFFFDEEEEEDD;?CCDB?CCDD@CCDDDDDDEEDDDDD
@2JL
GCCTAGGATATGGACAGAGGAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTAT
+
=18BD?B;BB?BD<EGEB3+<F>GH@ACFECGFICCAF1BFFF<?BG9)?DFF@CC=FF97)76@C7=EEEFD<;@3>@>;@BBBAB?@BBB::?A>@44:
@2JM
GTATGTATTCCATGAAGGAAGACTTGGAATTTCCAAGGTGCCGATTATCCATATCTCTGTCTAAGAAGCTGTCATGGAATAGGAAGAGGATGAGGTGTA
+
(-(-(.))))2)=@4=@)3)2(4.).=)9))).)1):3..))((((0.;>?).<1)0)))/)<=31>9>.3.<))<.))))))))6==/7-((-(-(((
@2JN
CGGGTAGGCCCCACATACCAACGGCGAGGATCACTTCAGCTCTGGCAGTTTTTGGTAGCTCTTCTGGATGACCCTTCAAATTCTCATTTTATTGCCTGGAC
+
=11<2??A+2<C1?A7A>B==?AA)44=AA>AB78.)==.>>AAA>);77>?@<==;>?B>?=,;,5(:=;9;9;783;8=?3;;=;???3;=;33:3988
@2JO
GTTGGCAGAGAATCAGGTATTAATGGAAGGACTCAATCAATCTGATTCTATAGAAGACCCTAACAGTCCAGCAGGAAGAAGGCATTTGCAGCTCCAGACTC
+
@;@DDDDDBBADFHIEBBC>HCGFHGGCHD?8:?ED<F9???B?BBFDD*BBGEHGHGHIEFGBC==AH7@D=6?16(6?;6=A>C@AA>@@5;A@C@@AC
@2JP
CTCCAGCACAGAAGGACAAACCTCTGGGTTGGGAAGGTCTCGGTTTGCAGAATAAATGGATACTTTTTGTCTGGTTTTTTTTTTTCTTTTGATTTTTTCTG
+
1+1+2+27+2+++2+++??+<++2?++1:::)0)*))00***(7'-(./)))/))))..))))))..),..((.6.;=(86-&&)+((3(((((+8(0(+(
@2JQ
GCGAGAAAGGAAGTCATCTTCATCCTCAGAAGACAGGAATCGAATGAAAACACTTGGTAGACGGGACTCGAGTGATGATTGGGAGATTCCTGATGGGC
+
B@CFFFFFHHHHHHJJJJJJJJJJJJJJJJJJJJJJIJIJJJJJIJJJJJIJJJJJJGIJJJJJJIHHHFFFCCEEEDEFDDDDDDDDDEDDDDDDDD
@2JR
GCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTC
+
@@@DDFFF>FD?FGDEEFAFIIFIFGGGGHHIGHGIGGDIGGIGIEFEHGFHEEHIIGHHAEEHHFFFFFDEACC;ACB?BCCBBAB?AB@AAC>CDCCCC
@2JS
TGATGTGATTGCCGGCTCCTCCAAGATGAAGGGCTTCTCGTCCTCAGAGTCGGAGAGCTCCAGTGAGTCCAGCTCCTCTGACAGCGAAGACTCCGAAAC
+
@?@ADDDAF?ACA8@DGHIGIB;?C:?CG@?GHG?FGIGG(?BBC=BC@8CFHG</;BEDE;C>A@>;@C@;A@A>AC@A>:559995>99:@>70855
@2JT
CGTAGAGTCGCTGGAGCGGGCGGCGCTGTGCGAGAGCCTCCTCACTTGGATCCAGACATTTAATGTGGATGCACCATGCCAGACCGTGGAAGATTTAACG
+
===+<<7?47AA=A3+@<8=)4A'5===,(5',3'0/8+88:<?8??:::?:3(+(+23(3(+(83383:38338(388(33;895&+58=32;;;878(
@2JU
CCTGCCTTCCTTGCAGAGGCCATGGAGGACGAGGAGAGACAGAAGAAGCTGGAGGCCGGCAAAGCCAAGCTTGCCCAGTTTCGACAAAGAAAAGCTCAGTC
+
CCCFFFFFHHHHGJJJGIIGJJIIIHIJGHHIIJEHEHGHGEHIJIIIJJIJGGGHHFFDBDDDDDDDDBCDDBDDDDDDEEDBBDDDDDDDDDDDDDDDD
@2JV
GCAAAAGCAACCAGGAAGTTCTGGAGTTTGTCACCAGAGAAGGCCGGATGGACCCACCCAAGAACTGCCCTGGGCCTGTATACCGGATAATGACTCAGTGC
+
7<;AAA3ABABB1+++<7C7443+<?2<?:1741:?A))):?=)9.(-7=().)->A'4,5(6;>>;;>=;;;=2;8(5(;5;;9;-&5:=?;?:??:;(3
@2JW
GTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGC
+
CCCFFFFFHHHHHIIJIJIJJJJJIFGHIJJJJJFHIJJIIJJJJJJJJJJJHHHGHFDEFFFEDEEEDDDDDDDDDD>@CDCDDB@DDDDDDDDDDDD
@2JX
CCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTA
+
CCCFFFFFHHGHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJIIIJJJJJJJJJJJJJJJHHHHFDBDDDDDDDD@BDDDDDDDDDDDDDDDDDDDDDDCD
@2JY
TGATCATATCTACACCACGCAAAGTGATGTATGGTCTTTTGGTGTCCTGCTGTGGGAGATCGTGACCCTAGGGGGAAACCCCTATCCTGGGATTCCTCCTG
+
CC@FFFFFHHGHHIJJJIGGIIJICHHIGEGIJIGIIJIJJJHIIIIIJIIHHIJJIEIIJIHIJHHHHFFFFDDDDDDDDDDDDDDEDDDDCDDEDDDDD
@2JZ
TGTCTACAAGTTTGTGTGTGATCCAGAAGCCCTTTTCTCCATGGCCTTTCCAGATAATCAGCGTCCACTGCTGAAGACAGACATGGAACGTCACATCAACG
+
@@BDFFFFHFDHHJGHEGEHIJIJJJJJIIJIJJJIJJJJIIIIIJIJJJJIJJIIJJJFIIJIGJJJIJICFHHHHBEFFEECEEEDCDDD@BCDDDDC@
@2K0
ATCTTTCTGAACAATTGAAACAGAAACATGGTGAGATTAGTTTTCTAAATGAAGAAGTTAAATCTTTAAAGCAAGAGAAAGAACAAGTTTCATTGAGATGT
+
;?;??ADD8DFDBA@HG<@><;C;GH>@ECCHHGIEE@FGB@FHGH<99BFHEC<?BBBFDEDHGGBCHB@F=CC>==ECAEC;BE@?DDD@>B666;(;5
@2K1
GTGGATTTCAAACAGTCCAGGCTCTCCGAGGACGGGCTGCATAGGGAAGGGAAGCCCATCAACCTCTCTCATCGGGAAGACCTGGCTTACATGAACCACAT
+
@@@D?DDFFFHFFGHIGI@EBGGCHIGGB@AHHGIGGGGIIIIIIIDEEEHHEFFDFDCEDDDDDCACCDC>@C@BBB?DDD=?BDCBCCDEDDDDDDDBC
@2K2
AGCTGAACAAGAAAGTAAACTTAATGAAGCACATAAGTCCCTTAGTACAGTGGAAGATTTGAAAGCTGAGATTGTTTCTGCATCTGAATCCAGAAAGGAAC
+
<@@BFFDDFFHHHDGAFGCBHBCAHHC9EEGGIICEHECGIEIH@BGBGHFGCDGI?<DH>FCEHECHGGICHIIIGCHHDEECCDFFEDBCEECCCB=AB
@2K3
CGTGGAGTAGGATGCCTGGATTTTTCAAAAGCAGATTCNNNTGTTCATTTATGTGTTATTGATGACTCCAATGAGCATATGCTTACTGTATGGGACTGGC
+
:=1=;DDDF>BA<3AAA:CGB><3<+A9+CF939?CG9###)088??FFFBFF/8988=CFD>C=CFC:=@AEFF)?;AC;7;B;;6>6;6;>?;(5=@<
@2K4
TGGTCGTACAAACTGCATCAGGAGATATGCAAACATATCAGATCCGAACTACACCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATGACATCTCCTGTG
+
@BCBDFDDHHHHHIIJJJIJIGHGHHJIJIIIIIIIJIIEGGIIGJJJJJJJGIJJJJJJJIIIJJEHHFFHGBDEFBCEE@CD;@CDCDDDCDCDDDCDC
@2K5
CTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGG
+
BBCFDDFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJHJIJJJJHHHHHHFFFFBCEEEEDDDDDDDDDDDDDDDD
@2K6
CAAGGCTTTAAGCAGGAGTACCACGACCCAGTGTATGAACACAACACCATGGTTGGCAGTGCGGCCAGCCAAAGCTTTCCCCCTCCTCTGATGATTAAAC
+
CC@FFFFFHHHHHJIGIICFHHIIGIJJJIJIGDHIIIGIIIJJIJJJIJJIFHIIIJE?CHBDDDDDDDDCDDCDDDDDDDDBDDDDDDCCDEECDDDD
@2K7
CAATTTGATAACTAAGCAGAATCAATTAATTTTGGAAATTTCAAAGCTAAAAGATTTACAGCAGTCTCTTGTAAATTCAAAGTCAGAAGAAATGACTCTTC
+
B@@FFFFFFHGFHJJIJJJJJJIHJJJIIGIGIJGIJGIJIIIIIGIJJJJIJEGIJHJJIIJIJIGGIIGFGHIGIEIIJHHGHGHFFFFFCEECEECC;
@2K8
GTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGCACCTGGGAGCTACCCCATGC
+
;:=BDDA;?DFFF<E:<CAB>@;11?@8*?9DFG;DFF;2BD@FFEC47=@;37??.7.7;3;;;((6.;;AAB?@B<(,,85:<?B(0(+49?BB9?A
@2K9
TGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTC
+
@@@DDDFDD=:DFHDGGFGHGGIGHGFHHICGAB?@>@FGEHGGICEHHICHIHBHHHGEFFFEEEEEECCDC>ACCBBBBBC?ABBBCBBCCCCCCCAC>
@2KA
CAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTAC
+
@@@FFFFDHHGDHGIBHHIIJJGJIJGIEGIIIGIJH?FIIIJEHIGCHGIIIIIJIIHFDB>BDDDDDDDDDD?BDBCCDCC@@@CCCCCDC?:>CC>AC
@2KB
TACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGG
+
=@?DDD=DHDH?BC@DFC@?:1@FH;8CFDDB:9BF?DFEHBDD@@??F==@FBFGC=@FFHG7C=A=E<?;;?A>@B?C@;AD>:ACA5,:>>ACAC:>:
@2KC
CAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTG
+
CCCFFFFFHHHHHJJJJJIJJJJJJJJJJJJJJJJJJJJJJJFHIJJJJJJIJHHHHFFFFEEEEEDDDDDDDDDCDDDEDDDDEDDEDDDDDDD>CDDDD
@2KD
GCGTGATCCAGCTGATGCCCAGCCCCATCATGCACCCTCTGATCCTGAACCCCCGGCACTCCGTGGATTTCAAACAGTCCAGGCTCTCCGAGGACGGGCTG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJIJIJJJIJJJJJJJIJJHHFFFED?BDBDDDDEDDDDDDDDDDDDDDCDDDDDDBDDDDDDD
@2KE
GAAAGAACGCTGCTTGGCTCATCCCAGCAGAACAGTAGGCTGTATGTTTGAAAAGGGCCCCAGGCAGTTTTATGATGACACGTGTGTTGTCCCAGAAAAAT
+
0(0-;):)<(((0).)@??7)<><>>@1399:77<).:39).(9)7)99<)>)/=;??('5(-5(.=863=9183(:=>5(',5(,,(7,,,((4(((+((
@2KF
AAGAAATGAGGGTTACCTATGGGACTGAAGGACTGCAGCAGTTACAAGAATTTGAAGCTGCCATTAAACAAAGAGATGGCATTATAACCCAGCTCACTGCT
+
@CCFFFFFHHHHHIJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHHFFFFFFEEEEEEEDDDDDDDDDDDDD
@2KG
TTTAAGGCGGCAGGTTAAACTCTTAGAAGAGAAGAATACCATGTATATGCAGAATACTGTCAGTCTAGAGGAAGAGTTAAGAAAGGCCAACGCAGCGCGA
+
CCCFFFFFGGFHHJHIJJJJJJJJIJIJJJJIJJJIJJJJJJJIJJIIJJJJIIIGHHGHHFFFDDFFACEEEDDDCDDECDDDCBBBDDDDDDDDDDDD
@2KH
GATTTCGCCGCCAGCTTTCTGAACCCTGTAACTCCTTTCCTCCTTTGCCGACGATGCCAAGGGAAGGACGTCCTATGTACCAACGCCAGATGTCTGAGCC
+
@@@BA>?DH@?CCFHIGCEEGIHFFGGGCGHCGGDFHIICFHDDHGICC;@;=EDFFCECCCCABBB@B@BB<?:>AA@BC>:?BBBBB?>:4>>C4>@C
@2KI
GCCCCTCCGGTCCCCCCTGGACAACATGATCCGCCGCCTCTCCCCGGCTGAGAGAGCTCAGGGCCCCAGGCCGCACCAGGAGAACAACCACCAGGAGTCCT
+
@@CFFFFFGFDHHGJIGIJGIJJIIGGGJIJIJJJGIIGHHGFFDD?BDDA?>@(8ACDADDB(877??BA?;9>B52?@88<8>A<A@?BDB??<?CD@C
@2KJ
CAGAATACCTATGGGCAATCGAGCAGCTATGGCCAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAACCTCCCACTAGTTACCCACCCCAAAC
+
<<5?<).))).26>:168))(2(:5)()))18(2)((7.3(>=1=)<<1)=)6>1)..)6).(...39>?;?(9).(.9((7((((,,375(:(,,56+8(
@2KK
CCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACA
+
BCCBDFFFGHHHHJJJIJIHHJJJJJIGJIIIIJGGIIGIEHIJGJIJJEIIIEGIIJJIIJJJHHDFDEECDDDCDDCDDDDDDCCDDCDDDDDDDDDD
@2KL
GGTAAATCTCATATTTTCTTCTGGACCTGGAGCGGCAATTCACTAACAAGAAAACAGGGAATTTTTGGGAAATATGAAAAGCCAAAATTTGTGCAGTGTTT
+
;7:+BDBDF4CDC:2CC@D@I<AAEFFD>CDGFGAF00*9DFF9DBFF>FFFII3..6@E2=?>EDDD8=AB>;BDAAB@:?@(59?BBBB@BB>>A@>@B
@2KM
GCAGTTACAAGCCTTCAAAAATGAAGTAGGAGTACTCAGGAAAACACGACATGTGAATATCCTACTCTTCATGGGCTATTCCACAAAGCCACAACTGGCT
+
@@@FDFFFHHHHHIJJJJJJJJJIJIGHIJJJEGHIIJJJJJJJIJJJJJJIJCGHIJIIJIIIJGGGGIHHFHHFFFFFEEEEEDDCDDDDDDDDDDDD
@2KN
CCTGTCTCCAGATCTCAGTAAGGTACGGAGTAACTGTCCAAAAGCCATGAAGAGATTAATGGCAGAGTGCCTCAAAAAGAAAAGAGATGAGAGACCACTCT
+
CCCFFFFFHHHHHJJJJJJJJJJHHJJJJJHIJJJJIJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJDEIJHHHHHHFFFEEEEDDDDDDDDDDDDDDDDD
@2KO
GGGCATATGGTTATCGAGGAAAGGACTGTAGAGCTAATGTTTACCTTCTTCCGACCGGGGAAATAGTTTATTTCATTGCATCAGTAGTAGTACTATTTAAT
+
@CCFFFFFHH<DHIJJJJIJJJIGHGHIGIIIIJJJJJJGHIJGHHGIJFHIJJJJIIFFCDDDCD>CDEDDEEEEEDDDEDDD@DCCDD@CDDEEEEEED
@2KP
GAATGGGGTTGTGATGGCCCAGGTTCTTCAAAAGATAGATCCTGCATATTTTGATGAAAATTGGCTAAACAGAATCAAAACTGAAGTAGGAGATAATTGG
+
CCCFFFFFFHHDFGGHHGIJJJJFHJJJJIJJJJJJJJIIJJIJJJJJJJIJJIIJJIIJJIJJJJJJHHHGHFFFFFFEEEEDCD@CDDCDDDDDDFDD
@2KQ
GAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCAC
+
<?@DFEFDHHHHHEGIIEHFHICH@HAAHHIGGGGFGGGIIEHHIIIIIGGH?AEFCDFFFCCCCB@BDDBADBBDBDDD:@CDDDCDDDDDDDDBDDBDD
@2KR
CCTTCTCAAAGTAAAAGATGATTTAGAAGACAGTAAAAATAAACAGGAATTAGAGTATAAAAGTAAACTTAAAGCACTTAATGAAGAGCTTCATTTGCAA
+
???D;??;CD?22<?<E+AFFBFBFIIACAAC?F*?CB3CEID**0BBDC?<<?9?B?D?BBB@=B888)=CAE:@3A@@>D?CD3;@3@;3;.6@6;>A
@2KS
GTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCC
+
@@CFFFFFFHHHHIIJIIJIJJJJJIJGHJJJGIIJJJIIIIGIGJIJFIIIJIGIIIJJJJJJGEHHGFFDC?B@BDDCDDDEEEF?BDB@BA<ABDDDB
@2KT
CTCTATACACACACAGCCGGAGGTCATACTGCATCAGAACCATGAAGAAGATAACTGTGTCCAGAGGACCCCCAGGCCATCCGTGGATAATGTGCACCAT
+
CCCFFFFFHHHHHJJJJJJJJJJGHIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHHHHFFFDDDDDDDDDDDDDDBDDDCEDDDADDEDDDD
@2KU
CTTGAAGCAGAGAATAGCATTCTTAAAGATGAAAAGAAAACCCTTGAAGACATGTTGAAAATACATACACCTGTTAGCCAAGAAGAAAGATTGATTTTCTT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJ;EIJJJJHHHHHFFFFFEEEEEDDDDEDEDEDD
@2KV
CCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGT
+
CCCFFFFFHHHHHJJJJJJJIIJIJJJIJIJIJJIJJJJJJGJIJJIHGIIJHCHHFHFFFFFFEEEEEDDDDACDDDDDDADDDDDDDDDDDDDDDDDDC
@2KW
AAAAATAATGGTGGAAGATAAAGTTTCTTTTGAAAATATGACTGTTGGAGAAGAAAGTAAGCAAGAACAGTTGATTTTGGATCACTTACCATCTGTAACA
+
@@?DDDDDFHG?CDBFGIEGIII<EHGGIIEHDHIIGGGHIGHIBDG;B?DDCHBDGBDFHAFHCGGCHEEHGIGGHGEEEFBDDFC@CEECCCC>@CCC
@2KX
AAAAGAAAGACAGTCTTCTGAAGAAATAAAACAGTTAATGGGGACAGTCGAAGAACTTCAGAAGAGAAATCATAAAGACAGCCAGTTCGAAACTGATAT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJIJJIJJJJHIJJJJJJJGIJJJHIJJJIJJJJJIJJJIJIJJGHHHHHFFDFFEEDDEDDDDDDDDDDDDDDD
@2KY
CTGCTGCTACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTG
+
@CCAAEFFHF?FHIFHIIEGGIGGGGGDEHHIIJFIIIJ0?DDGGICGIIIIGIJJHHCFGGI)@7=AEHHHE;BCDCDDBD@?B?CDDCDCCDDD?4>CD
@2KZ
GAAAGAACCCCACAGTCCATGTTCAGAAATCAGCTCTGCCTGCAGTCAAGAACAGCCCTTTAAATTCAGCTATGGAGAAAAGTGCCTGTACAATGTCAGTG
+
@@@AADBDHFABFGI<@<FAEHFBHFHIEGIGG@BHGGIGIBHIIH@BFEGGIIGGGFHGHHG@CHH@DEHCEAAHEDD@D>@CA>ACCCCCCCACEDC::
@2L0
GTCTGAGCCAAACATCCCCTTCCCACCACAAGGCTTTAAGCAGGAGTACCACGACCCAGTGTATGAACACAACACCATGGTTGGCAGTGCGGCCAGCCAA
+
?:?1:2ADFFDFFIIBFE?;CGGB??FDFF;GFFIIII>FFIDG?F?D@CF>BFE>EEEEF?:?B?;;;>??CBBBBAABBBBBBBB(4>>@BBB1<BBB
@2L1
CCAGCAGAACAGAAGGCTGTATGTTTGAAAAGGGCCCCAGGCAGTTTTATGATGACACCTGTGTTGTCCCAGAAAAATTCGATGGAGACATCAAACAAG
+
CCCFFFFDHHHHGIGIIJJGIJJFHHIIJJJJJJJJIJJJJIJJHHJIIGGHIIJJIJGIIHGJJGHHGHFFFFFEECEDBCDECDD??CDDCCCCDDD
@2L2
CCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATAC
+
C@CFFFFFHFHHFEHIJJJFJJJCEHDBEGB?1?FGEDDFCGEDCFEGGIHIII=DECDEEEHD;BFEE@EEEED@@C@CCACCC?ACBBDDB@BD?C:C
@2L3
GGCTGAAAATGAGTTTTCTTTAAGGCCAATTGACAGCAACACGTTTGAAATGAATGGCAAAGCTCTCCTGCTGCTGACCAAAGAGGACTTTCGCTATCGAT
+
@<<?DFDBFAHAF?DGHEGIICIC??FHGFEHEFIFA@GGBGGBGGGIII<F8?FGE@GC;F3=CGGHG7CCC>=A=;);?BE6;=,;?C>C?;=?@A<<2
@2L4
CAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTC
+
CCCFFFFFHHHHHJJHHIIIIJJJJJFHIJJJIJJJJJJIJIIJJJJJJJJJJJIJJIJIJJJJJHHHFFFFFEEEEEEDDDDDDDDDDDDDDEDDDDDD
@2L5
CCTGTCTCCAGATCTCAGTAAGGTACGGAGTAACTGTCCAAAAGCCATGAAGAGATTAATGGCAGAGTGCCTCAAAAAGAAAAGAGATGAGAGACCACTCT
+
?@@DADFFDDHDHIGEGICF@DF<C@?@;:?EH4C?DFHGH@?3?@BF9B@GID3=BBDGGGGGGG@7@C;7AH;CHBB;ACCA;5=;;;;ACB5?CBC<C
@2L6
GTCGTACAAACTGCATCAGGAGATATGCAAACATATCAGATCCGAACTACACCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATGACATCTCCTGTGAC
+
@@@DFFFBHFDFAHEGBFHGHGJJGC@<HAHAGBFDBGBHE;9D?B@GDBHHHIIDHGGCHGGGEHDDEGHFEHB@DD>);C;?>;>;->A;@CDCC>>>A
@2L7
CGGGACTCGAGTGATGATTGGGAGATTCCTGATGGGCAGATTACAGTGGGACAAAGAATTGGATCTGGATCATTTGGAACAGTCTACAAGGGAAAGTGGC
+
CCCFFFFFHHHFHGIJJJJJJJJJJJJJJJJIJJJJJIJJJJJJJJIIJJIIJJJJJJJJJJIJIHHHFHHFFFFFFDEEEECDDDDDDDDDBDDDCDDD
@2L8
TTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJIJJJJHIHHHHHFFFFFEEEEEEDDDDDDDDDDDDDDDDDDCDEDD
@2L9
GGAGATATGCAAACATATCAGATCCGAACTACACCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATGACATCTCCTGTGACTCTCACCTCTCAGACAAC
+
?:;4+2A??DD>DE?DEEC>DFF;AF=AE=EE9C?><DDB***:?DEDD9D9@>9.=B9.7A=C@=7@;C=?>A>CA?A?AD3>@AAAA>>;>>;->>,9,
@2LA
GTGCTTATAAACGAAGACAAAGAGTTGGCTGAGCTGCGAGGTCTGGCAGCCGGAGGAGGCCTGGCTAATGCCTGCTATGCAATACATACTCTTCCAGCCC
+
111=BD?BFFD?FF;?1<<F?C<E9AE@FFDG?C41:6DDD7;/=88)5;(5;AE'5;=@=A?BBBBB(:3,5>2(>3>:@44+++:4++((::4:(+22
@2LB
GAAGAAATTGCTCAAAGATGCCATGAACTGGATATGCAGGTTGCAGCATTGCAGGAAGAGAAAAGTAGTTTGTTGGCAGAGAATCAGGTATTAATGGAA
+
CCCFFFFFGHHDFJJIIJIIIIJIGIJIJIIIGGIJCEHHFHIGGGGFHEIFEIJJFGGEHIJDG=CHIHICDGHFFHFEEFECCCAE6>CCC@CDDDD
@2LC
GGGGGACACGTGAATATGGCATTCTCTCAGTCCAACCCTCCTTCGGAGTTGCACAAGGTCCACGGATCCAGAAACAAGCCCACCAGCTTGTGGAACCCAAC
+
??8??D@DD<+ACE@?CB98<?CDEE?CBC?DD@CDIIIDDDDCDD;AC@=D@@C@CC7=C;=C@8,96>>>AAA59=?????9><?::>(:84:3<??>0
@2LD
CCTACTCTTCATGGGCTATTCCACAAAGCCACAACTGGCTATTGTTA
+
@@@FDFFFHHHHHIIIJJJIJGIGGHGGIIJJJJJJJJHGIJIJIJE
@2LE
GGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTT
+
CCCFFFFFHGFHHJJJJIJIJJIIIJIIGHIIJJIJJIIJGHIIJIHEGHIJIJIIGIIGGHGIJIIHHHDHFF@EEFDEBBBDDDDD@CDCDCCDDCDD
@2LF
TTCAGATGATAGCCGTAATAAATTGTCGAAAATACCTTCAACACCCAAATTAATACCAAAAGTTACCAAAACTGCAGACAAGCATAAAGATGTCATCATC
+
;@?DDA;BF?C4A<<<@CAA?AFBB<9<EHI<:11:::9::0???FHI;8BFH>B<FACHI>7@;=)===E9D@BB>>ABA5?5@>@C@(,(;:;@AC5@
@2LG
GAATGTTCATTCTTATGACCCCCAAGGAGAAGGCAGGGTGGATCCTGATCTGTCCAAGCCTAAAAACCTTGCTCCTTTACAAGAGAGTCAGGAGTCTTAC
+
CCCFFFFFHHHHHJIJJJJJJJJIJJIJJGIJJJJJIJIJGIGIIJJIJJJJJIJJJIJJJHHHHHFFFFEEEEEECDDDDDDC@CD@CDDDDD<CCDDD
@2LH
CAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCA
+
CCCFFFFFHHHHHJJJJJIJJJJJJJJHIIJJJJJHIJJJJJJJIJJJJJIJJJJJJJJJIJJJJJJJHGHHFFDDEDEDDDDDDDDDDDDDDDDBDDDD
@2LI
CCCTATGCTGGGATTCCTCCTGAGCGGCTCTTCAACCTTCTGAAGACCGGCCAACGGCTGGCGAGGTCCGACTAATGCAGCGAGGGGGTGTACCGCCTGAT
+
(0-286))..)((.<@@))))<2..@@((<?)>)):=66>))))))0='';''((,,'3''(,3')&(())5&&((+8++(0&)500&5&5/:(&&)52(5
@2LJ
CCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGT
+
CCCFFFFFHHHHHJJJJJJJHIJJJJJJJJJJJJJJIJJJJJJJJJJJIJJJHHHHHHFFFFFFEEEEEDDDDCCDDDDDDBDDDDDDDDDDDDDDDDDDC
@2LK
ATTTGGAACAGTCTACAAGGGAAAGTGGCATGGTGATGTGGCAGTGAAAATGTTGAATGTGACAGCACCTACACCTCAGCAGTTACAAGCCTTCAAAAATG
+
@@@FAE?DHFFFHGIBHIIIIFHGIHGGIIIIFDGEHEBFEDHG>@GHIICDHIIIEHEFHGHG>9@GEHIIF@EHH;@@;@;A>>CE>BBDDACDDDDBD
@2LL
TACAGGGACTTCAGACATTAACCATGACAAATTCAGGCAGTACTCAGCAAGGTACAACTATTCTTCAGTATGCACAGACCTCTGATGGACAGCAGATACTT
+
?1;:DADBFBH?CGH>AHHHCHIIF>CCDDHG44**?3D;G<BF@9B<DHGC?BDBFF<3BF4@FAHD@74@)7=;>CEHC?>;>BDCC@CC==?CCA3:@
@2LM
CCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACA
+
CCCFFFFFHHHHHJJJJJJIJJJJJJJJJIJJJJJJJJJJIJJJJJJJJJJJJIJIJHGHIJJJHHFFDEDEDDDDDDDDDDDDDDDDCDEDDDDDDDDD
@2LN
CTTCAAGAAAAATTTGCACAACTTGAAGCAGAGAATAGCATTCTTAAAGATGAAAAGAAAACCCTTGAAGACATGTTGAAAATACATACTCCTTTAGCCA
+
;??D;?B>?CFAAFGB><?@FAB>C<F4EB?F=CADF@A9DEDGG9?BDBBF9B<FA7FFCFFBFFCEFA:DA;)=;ADBB?BDA@ADCBABBB@B@B>A
@2LO
CTCAGCAGTTACAAGCCTTCAAAAATGAAGTAGGAGTACTCAGGAAAACACGACATGTGAATATCCTACTCTTCATGGGCTATTCCACAAAGCCACAACTG
+
CCCFFFFFHHHHHJGBGHIIJIJIIIIGIH@GIIIHFHHIIIJJJJJIIJJJJIIIIAGGIGIJJJIJJHGHHHGEFFFFCBCEEEEDDDDDCDDDDDDDD
@2LP
GTCATCAGAATGCAAGATAAAAATCCATACAGCTTTCAGTCAGATGTATATGCATTTGGAATTGTTCTGTATGAATTGATGACTGGACAGTTACCTTATTC
+
@@BFFFFFGHFHHJJJJIJJJJJJJJJJJJJJIJJJIJJIIIJIJIJGIJJIIJJJJJIJJJJIBHEGGCCFHIIJJIIJIJHIJFHHHFFFFFFEEEEEE
@2LQ
GAACTGTTGCACCGCTCCAGGTCACCTATCACGACAAATCACCGGCCTTCTCCTGACCCCGAGCAGCGGCCCCTCCGGTCCCCCCTGGACAACATGATCCG
+
CCCFFFFFHHHHHJJJJJJJJHJIJJJJJJJIIJJJHIIIJIJJJIJJJJJHHHHHFFFFDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDBDDDDDDDB
@2LR
TGCAAAGAAACCCACAGCTGCAGAGATCTCTGTTCGAGTCCCTAGAGGGCCGGCCGTGGAAGGGGGACACGTGAATATGGCATTCTCTCAGTCCAACCCTC
+
CCCFFFFFHHHHGJJJJJJJJJJJJJJJJJJJJJJJJJIIJJJJJJJJIJJJJJHFECDCDDDDDDDDDDDBDDDEEEEDBDDDCEDDDDDDDDDDDDDDD
@2LS
CTAACGTGAAAGCCTTACAGAAATCTCCAGGACCTCAGCGAGAAAGGAAGTCATCTTCATCCTCAGAAGACAGGAATCGAATGAAAACACTTGGTAGACGG
+
@@<DDDBD<C?DFFGAG>EHCE:CEEII<B3C8C3?D@?:F6?AFFFEEE<BCFF@AECDCEEEEAEEAE9?BBDB>@;@B<>ABBB?BBBAA@:@A@:<B
@2LT
CGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCT
+
@@@DFFFFHGHHHIJJIGIIJJHIGIIHIIIIIIJJJJIJJIJGGIIIGGGGHIJHGIJJIIGJIGEHCEHHFFEFDD?DDAAACCCDDDDDDCCBADBBD
@2LU
CTCCATTTATATGAGGCAAGAAGGCTTCCTGGCTCATCCCAGCAGAACAGAAGGCTGTATGTTTGAAAAGGGCCCCAGGCAGTTTTATGATGACACCTGTG
+
??@FFFFDFHHDDFHGGACFGAGGFGEB<B?FHGCDDDHGIIIIIGGIHI@FHECBC=CCF@FE@@GGIIFH=?8<ACAABBCC@;>>@@@;@C>A<:?@>
@2LV
CAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCC
+
@;=;?BDB:AFD?:<@G+A:<CG6CFIE:???@<?BDG@FFFIICF>=FE;FF>;D;D;CAE?BDD;?DA;;@>@AB;;>A<@B>B82(2:@@B>>?<828
@2LW
CACCCACTAGCACTATTGCCCCTGGAGTTGTTATGGCATCCTCCCCAGCACTTCCTACACAGCCTGCTGAAGAAGCAGCACGAAAGAGAGAGGTCCGTCT
+
???;A;BDD++<ABDBD@E?AF;E=8AEE*1)*:?*39<BDEI;?D?;>3?=B>C)7A;)=(.6)(=;=AA;)77;>;>A?;3;;8:9,,((++3>&+(+
@2LX
CAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGG
+
<??1BBD+=C8CD6EEE<FEE:B49?DDD@BDDA>>DBD?B9DDC.;BDDIC8@777@;A?3?DC@DDA>A@>???????3>:>AA8>??<<<>(+4:995
@2LY
GGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCT
+
@@@DDDDD?AD?DFB?FAEEHGIFHG@GG<FDHB?BGD?FGBGGHEHGFGGGIIIIEIGIGEGEGDCGHHHHHHFEEEEECCCCCCCBBCCCCCCCCCBC
@2LZ
AGACCACTCTTTCCCCAAATTCTCGCCTCTATTGAGCTGCTGGCCCGCTCATTGCCAAAAATTCACCGCAGTGCATCAGAACCCTCCTTGAATCGGGCTGG
+
<@@DFFDDHAHAFBEEBGGA@FFHGBFFHGGGF@CBHHIDD??DGEDBGGHGI@EHAGGHCHE@;@C?BCDB>CCDCCDDDDB??A?ACD:A@CDBDBBB@
@2M0
CAGGTTTGTCTGCTACCCCCCCTGCCTCATTACCTGGCTCACTAACTAACGTGAAAGCCTTACAGAAATCTCCAGGACCTCAGCGAGAAAGGAAGTCATCT
+
?@BDDDDFHHHHHJIJJJJJJJJJJJJJJJJJJJJJJJGJJJJIJJIIJJJDHHHGGFFFFFEEEEEEDDDDDDDDDDDCDDCDDBBDDDDDDDDDDDEDD
@2M1
ATGTGGCCTCAGTGAAAAAATCAGTCTCAAGTAAAGGCCAACCAAGCCCTCGAGCAGTTATTCCCATGTCCTGTATAACCAATGGAAGTGGTGCAAAC
+
BCCDFFFFHHHHHJJJJJJJJJJIJJJJJJJIHIJIHIJJJJJJJIJJJJJJJJJJJJGHHHHHHFFFFFFEEEEEFEEDDDDDDDDDCCDCDDDDDD
@2M2
TAACGTGAAAGCCTTACAGAAATCTCCAGGACCTCAGCGAGAAAGGAAGTCATCTTCATCCTCAGAAGACAGGAATCGAATGAAAACACTTGGTAGACGGG
+
<;??D?DDB?FADFGFEGGGEG@<BGCAF@D;EEFDF9D<FD@@BFABH@BCA@ADDG>@DE;.7=?CC3=?B@>:(6>>3>5;>>(99>>AC5:@>599>
@2M3
GCTCAGTCTCTGAAAGATGAGATCGACGTGCTGAGACATTCTTCTGATAAAGTATCTAAACTAGAAGGTCAAGTAGAATCTTATAAAAAGAAGCTAGA
+
CCCFFFFFHHHHGJIJIIJIGIIJIJJJHGIJAHIGHIJJJIIJJJIJJJJJGHIIJJJJJJEIIJJJCGHIHHHHHHGFFFFFFEEEECBDCDDDCD
@2M4
GGAAACCTCAAGCTGAGAAAGTTGATGTGATTGCCGGCTCCTCCAAGATGAAGGGCTTCTCGTCCTCAGAGTCGGAGAGCTCCAGTGAGTCCAGCTCCTCT
+
@C@FFFFFFHFHGIIEHFIEHEHH@FHGIIGGGHIJJJGGIJIIAHHHGIDHGJJDGEHIIEHH?DDFFFFEEDB;8=?BDDDCCDDC@>CCCCDCADDDD
@2M5
GCATGGATTACTTACACGCCAAGTCAATCATCCACAGAGACCTCAAGAGTAATAATATATTTCTTCATGAAGACCTCACAGTAAAAATAGGTGATTTTGGT
+
CCCFFFFFGHHHHJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJIJBFHJJJJJIJJJJJJJJJJJJJIIJHHHGFFFFFFEEEEEEDCCDDEEDDDB
@2M6
GGCAAAGCCAAGCTTGCCCAGTTTCGACAAAGAAAAGCTCAGTCGGATGGGCAGAGTCCTTCCAAGAAGCAGAAAAAAAAGAGAAAAACGTCAAGCAGTA
+
1+:AB?;3+CDDDA@EEI@FBFEF>BFAEDICEDCBDD9?DD9BDDI;@C@>@AAD)7=CD;37?A;@A3>@AAA?????;<>?AA??35<<<;:><3:A
@2M7
AGAAAAGTAGTTTGTTGGCAGAGAATCAGGTATTAATGGAAAGACTCAATCAATCTGATTCTATAGAAGACCCTAACAGTCCAGCAGGAAGAAGGCATTTG
+
CCCFFFFFHHHHHJIJJJJJJIIIJJJJJJCGIIJIJJJJJIJIJJJJJJJJJJJJJJIJIJJIJIJIEGIJJJIJHHHHHFFFFFEDDEDDDCDDDDDDD
@2M8
CTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTC
+
===1?+2A==A77@+2>++?,?A@<@=++AA9*@A7?7?=?0)0?0)=((0=>AAABBB>AA)=)==;AA<@7><>>;3(-;?==9(9;====:>?:9:88
@2M9
CCTAGAGGGAAAGCGAGAGGGAGACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGC
+
C@CFFFFFHGHHFIJGGGJJJHEHIIIGEGDHG?FGIJIHH@EHAEF;BADBCBB?CDDCDDDDBBDDDDBBBDDCCDDEDDDDDDDCDDDBDCDCDDCBB
@2MA
CTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCC
+
@C@DFEBDHHFHHHGAHGIIIIIIIIIIIGIIIIIIIIIIDHGIIHIIIIIGIIIIGHIGGGHFHFFFFFEEEEDDDDDBBDDDDCDCDDBDBDDDCDD
@2MB
CTATGATAAAAACATTATGACCAAAGTGCACGGCAAAAGATATGCTTACAAATTTGACTTCCACGGCATTGCCCAGGCTCTGCAGCCACATCCGACCGAGT
+
CCCFFFFFGDHHHJJJJIJJJJJJJJHEGHGIIIIGCFHGGEIGHJIIEHIJHIIFGIIIGHGIIIFGFFDFFEDCDDBDDDDDDDDDDDCCC<BDDBDB?
@2MC
CTCTGCCTGCAGTCAAGAACAGCCCTTTAAATTCAGCTATGGAGAAAAGTGCCTGTACAATGTCAGTGCCTATGATCAGAAGCCACAAGTGGGAATGAGGC
+
CCCFFFFFHHHHDIJJJIJGHIIJIJJJJJJJJJJJIIIIJIGJGGIJJDGHJJIGHIJJJIIJJJHIJIJJJJJJJHHHGFHFFFFDD3@CBBD@DDDDB
@2MD
CACATGCCAAGGCAATCTCCTTATCATGGGGACTGAGGATGCCTCCTCCTTGCCTGAAGCCAGTCAAGAGGCAGGGAGCAGAGGCAATTCCTTTTCTCCTC
+
@CCFDDEFGHHHGHJE@FIIJIIHIJJJJGIGHHEGHCHFBFHGHICHIGEGIHIEHGGHDAGHGGEH@EHFEFDC=@B@?CDB@BBCDDD>CDCDDCC:9
@2ME
CAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCA
+
<<@B;D;;ACFFFF9;EE<F+<3,ABGA?EACG=;GCG9DG@FFEE;G<=FII9;;C(.(=@;ECAD7?A1=BDC?C?3>A(;5=@ABB@BBB9?2:>>A
@2MF
AGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATAT
+
1:8AD?DDF3?;;C+<AF9@GB6:ECADF6?<?0B9098B?D*98BF?;;C;;@C/8ADBC>@87??@B:5:5;>ABAB>5<5>B<<8<(+299(4+8+:4
@2MG
CAGAAGTCATCAGAATGCAAGATAAAAATCCATACAGCTTTCAGTCAGATGTATATGCATTTGGAATTGTTCTGTATGAATTGATGACTGGACAGTTACCT
+
CCCFFFFFHGHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJIIHGIIJJJJJJJJJJIJJIHIJJJIJJJIJJJJIJHHHHHHFFFFEEEEEE
@2MH
TCTTCAAGAAAAATTTGCACAACTTGAAGCAGAGAATAGCATTCTTAAAGATGAAAAGAAAACCCTTGAAGACATGTTGAAAATACATACTCCTGTTAGCC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHHHHFFFFFFFEEEEEEDDDDDDDDDD
@2MI
GGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTAC
+
=;;?D=;D@<::CECFH<BFFGEE=?DG=10BD9B*?999DEDEHI8BCECCHGHGEHEH(.6(6;BBECBCCC>:@C@C>?BBB7@<1:>>9:@CACC
@2MJ
GGACAGTCGAAGAACTTCAGAAGAGAAATCATAAAGACAGCCAGTTCGAAACTGATATAGTACAACGAATGGAACAAGAAACACAAAGAAAGTTAGAACA
+
CCCFFFFFHHHHHJJIJIJJJJJJJJGIIJJJJJJJIJIJIJJJHJJJJJJIJJJJJJJJGIJJJIJHHHHFF;@EEDECEDDBDDDDDDDDDCEDDDDD
@2MK
CAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGC
+
@;?D?DDA<8DDD?FEHHGHIIIGIIICFHGHGIBFGHIIIIIIIGGGGCDGIHIEHCHIIHFFFFEEEECDC@ACCCCBBBCCCCCBBBBCCCB9@BBB@
@2ML
AGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGAT
+
<<<DDFFAFFDDDHIDHGHGIGIGGHGGBHGECHHDDFD@BGHIIGEGGGIGEGC@@EHHEHEFFDFF@CCEEE@BC=9@BCCCCB8<AB@BBBB?@ACCC
@2MM
CCAGGAGAACAACCACCAGGAGTCCTACCCTCTGTCAGTGTCTCCCATGGAGAATAATCACTGCCCAGCGTCCTCCGAGTCCCACCCGAAGCCATCCAGCC
+
CCCFFFFFHGHGHJIIJJGIJIIGIIIIIJGIEGCGGIIIIGIIJBFBGGFAFHGIJIGIIIIIIGDEEHDDFDEEDDB?CCDD?@BD<BD9ACCDDDDCB
@2MN
GAAGAGGTGGCCCGACGTTGGGGCATTCAGAAAAACAGGCCAGCTATGAACTATGATAAACTTAGCCGTTCACTCCGCTATTACTATGAGAAAGGAATTAT
+
CCCFFFFDHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIHHHHHHHFFFFFFEEDEEDEDDDDDDDDDDDDDDDEDDEEDDDDDDDDDDDDDE
@2MO
CCCGGATCCCCCGACAGAGCGGCGGCGGTGTCTGGCCAGGCGGTAGGCGCTGCCTGGCCGCGGCGGGGGAGATGTTCAGCGGAGAGTCGCTGGGGCGGGCG
+
@CCFFFFFHHGHHJIJJJJJJJJJHEDD0::CCCDDDCABB7B@BBBC@8&55B:3<<B7<BB;7BDD&00&((+:((4()&)&)2(())&)9(5&09@&)
@2MP
ACCCCACGTCAGAGTGTGGGATTCTGTTACTCTATCCACACTGCAGATTATTGGACTTGGCACTTTTGAGCGTGGAGTAGGATGCCTGGATTTTTCAAA
+
CCCFFFFFHHHHHJHHHHIJGIJJJJJJIJJJJJJJIIJJJJJJJIJJJJJJJIJJIJJIJIJJJJJJHHFH<BCACCCDDDDDDDDDDBCDDDDDDDD
@2MQ
ACAGAACTCATGGAAAAACTTGAGGTAACCAAGCGAGAGAAATTAGAGCTGTCACAGAGACTGTCTGATCTTTCTGAACAATTGAAACAGAAACATGGTG
+
CCCFFFFFGHHHHJJJJJIJIJIJJGHIIIJJJIIGHGIIIIJJJJIJJJJJJJJIJIIIJJJGIJJHFGHHHFFFFFEFEEEDCEDDDCDDDCDDDD5>
@2MR
AGATCATCGAAATCAATTTGGGCAACGAGACCGATCCTCATCAGCTCCCAATGTGCATATAAACACAATAGAACCTGTCAATATTGATGACTTGATTAG
+
<?;DDDBDD?FDCFEHEGDH@A?ECDAHAFDFFIIHEGAGIGIGIIGEHGIIECCA?A>@DE@@CA?BCCCCC>==A:>ADD>@@CCCCDCCCCCC@C>
@2MS
AAAGAATCAAAAAAGTGCCAAGGAAGGGGTGACAGTGCTTATAAACGAAGACAAAGAGTTGGCTGAGCTGCGAGGTCTGGCAGCCGGAGAAGGCCTGGCT
+
@@;D1BD?CFF?FA@GA<AFGAD;?BBF@0:?D9DFF>BB9?98=8BF5;;=CEIF>=CABB@;1>BA@;;938;=@B@9><<<?05<0&2(2??:8<@B
@2MT
AGAAGACCTTGGTGATTTAAGGCGGCAGGTTAAACTCTTAGAAGAGAAGAATACCATGTATATGCAGAATACTGTCAGTCTAGAGGAAGAGTTAAGAAAGG
+
CCCFFFFFHHHHFHIJJJJJJJJJJJJJJIIJJJJJJJJJJIJJJJJJJJJJHHHHHHFFFFFFFFEEEEEEDEEDDDDDDDDDDDDDDDDCDDEDDDDDD
@2MU
AGCTAATGTTTACCTTCTTCCGACCGGGGAAATAGTTTATTTCATTGCATCAGTAGTAGTACTATTTAATTATGAGGAGAGAACTCAGCGACACTACCTGG
+
CC@FFFFFHHHHHJJJJJJJJIIIJIJJIDFGDGGHHGDGIJFHIIGCDHHIGIEEEEHHHCDCEFFFDEECEC>@A@B?BBDCCCDCCDDBDBDDDDDCD
@2MV
CCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATG
+
CCCFFFFFHHHHHJJJJJJJJJJJIJJJJJJIJJJJJJJJJJJJJJIIJJJJJJJJJJIIJIJHHGFFDFDDEEEEEEDDDDDDDDDDDDDDDDCCDDDED
@2MW
CAAGCAAGAAGAGAAAAGGATGAGACAATGAGAGAATTTTTAGAGTTGACAGAACAGAGTCAAAAATTACAGATTCAATTTCAGCAATTACAGGCTAGTG
+
CCCFFFFFHHHHHJJJJJJJJIIJJJJJIJJJJJJJJJJJJJJJJGIIJJJJJJJJJJJHHHIJJJJJJIJHHHHHHFFFFFFFEEEEEEDDDDDDDDCD
@2MX
CCTGGCTTACATGAACCACATCATGGTCTCTGTCTCCCCGCCTGAAGAGCACGCCATGCCCATTGGGAGAATAGCAGACTGTAGACTGCTTTGGGATTACG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJHIJJJJIJJJJJJJJJJJJJJJJJJIJJJJJJIHHHHHHFFFFDEEEEDDDDDDDDEDEDDDDDDDDDDDDDDDD
@2MY
CCAGTGTCCCCACTGCATCATGCATCTCCAAACTCAACTCATACACCGAAACCTGACCGGGCCTTCCCAGCTCACCTCCCTCCATCGCAGTCCATACC
+
@@@DBDADFFHHFEIIIIGGHGHIEHHGIIEIIIIII@DHIIIIGIIFIIGIIGGHGIGGEHECCCCCCCB@A@@BCBBB<C??@C7?@B<ACCECCC
@2MZ
ATGGTTGGCAGTGCGGCCAGCCAAAGCTTTCCCCCTCCTCTGATGATTAAACAGGAACCCAGAGATTTTGCATATGACTCAGAAGTGCCTAGCTGCCACTC
+
<??D?:DA>F142<@88CADC?GDCF;*BFDAGIDEFEFI8CF>@FFFE9@)=CE>E@1=?B9=BAACB@>ADBBA>BA@ABA:5,5>>@>?A3:>@:+:<
@2N0
CAAGGCTTTAAGCAGGAGTACCACGACCCAGTGTATGAACACAACACCATGGTTGGCAGTGCGGCCAGCCAAAGCTTTCCCCCTCCTCTGATGATTAAAC
+
CCCFFFFFHHHHHJJJJJGHJJJJJJJJJJJHIHIJJJJJJJJJJJJJJJJJGIIJJJHHHHFFDDDDDDDDDDDDDDDDDDDDDDDDDDDEDEEEEDDD
@2N1
CTACAGTGAAAATGAAAAGTTCTGTCTTTGATGAAGACAAAACTTTTGTAGCAGAAACATTGGAAATGGGTGAGGTTGTTGAAAAGGATACAACAGAACTC
+
CCCFFFDDFFHGFHGIIIJCIGICHHIJJIGIJJIIHIIIGHIIIJJGFHIGHEIJJJIIIIJIJJJJII@FHGGHGHEEDFFFEFCACCCDDDDDCDDDD
@2N2
GCCCCTCCGGTCCCCCCTGGACAACATGATCCGCCGCCTCTCCCCGGCTGAGAGAGCTCAGGGACCCCGGCCGCACCAGGAGAACAACCACCAGGAGTCCT
+
BCCFFFFFHHHHHJJIIIJJJIJIIJJJJJIIJIJIGIGHGHHEFFDDDDDDDDDDDDDDDDDDDDDDDDDD@DBDDDDDDDDDDDDDBBBDDBDDDCDDD
@2N3
TGCGGCTAGCAGATGAAGATCAGCGAAATCAATTTGTGCAACGAGACCAATCTTCATCAGCTCCCGATGTGTTTATAAACACAATAGAACCTGTAAATATT
+
7((-(@(((.2=;:9=8))).))2((((.<1)))0).0:<8=(7/<3=)(8))::=36>.)).)(''''69-(7=131;:0(78(5:;=(8<3((+5::((
@2N4
ATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCA
+
;:=BDDDDHFF?FBGB?FEHGDGEH@EH@DF?@G@DG?GEHC>??CDDGG<7CH@@B4?DE=;;AACCCCBCCCC;>AACCB?9?BB8?<??CC>@@@BC
@2N5
CCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTTATGGGCAGGAGT
+
C@@FFFDFDFFGCGAFFH<IIDDEHBHG@GHCE?EFCBGFEHGAHGDHCBD=FHHGIEGHBHEEFFECA=??BBBCCCCCECBB595?C>CCCCCCBB??3
@2N6
CCTGACCGGGCCTTCCCAGCTCACCTCCCTCCATCGCAGTCCATACCAGATAGCAGCTACCCCATGGACCACAGATTTCGCCGCCAGCTTTCTGAACCCTG
+
@8?D?D>AFFFFFIBFII>E<?GEEFII=GFFIIFEECFIFDFIIFFIIA;=7.==(7??BDD7AB>(5?5;=?BABB>5;/9959><>BBBAADA48@B<
@2N7
CCTTTAAATTCAGCTATGGAGAAAAGTGCCTGTACAATGTCAGTGCCTATGATCAGAAGCCACAAGTGGGAATGAGGCCCTCCAACCCCCCCACACCATCC
+
@@@ADD?DFFDHHIIG@EHHAFGGEGHIDHHHFEGHGHIBGHGF9@?B>FB?BDDEEHII>FECG;=CF@EEG>GEHHGCADBBCCAB;@BB@<@BBB@CB
@2N8
CTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJHIJJJJHHHHHFFFFFFEEEEEEDDDDDCDDDDDDDDDDDDDDDDDD
@2N9
GGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGCCCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACAC
+
++1=BD2:=CBD?4AC22AEEEAEF9@E+?FBEI@?8):?D3D8B;;DE<9?C;=).8>=@A).=)(6A>C@>7;>@;>@9>A>;A?>AAA;AAAAAAA(
@2NA
CTTTCGCTATCGATCTCCTCATTCAGGTGATGTGCTCTATGAACTCCTTCAGCATATTCTGAAGCAGAGGAAACCTCGGATTCTTTTTTCACCATTCTCC
+
CCCFFDFFHHHDFIJJJIHGHCHIJIEEEGGGIIJIIGGHIHIGGHGHIJJIIJGDHIGIIDGHIIIIIIIJJFFFHFFFDDEEEDDDDDDDDDDDEEDD
@2NB
TGATGACTGGACAGTTACCTTATTCAAACATCAACAACAGGGCCCAGATAATTTTTATGGTGGGACGAGGATCCCTGCCCCCAAATCTCAGTAAGGTACGG
+
=>=AAAAABB7+<AA@,?3?,+<7,?A<++22@4)@5)1:?)):0)0=/?7?BBB<.)==/=A'(6/'59/((555((,(537((+(++(+(53::+8(59
@2NC
AGAGAGATATGTCTACAAGTTTGTGTGTGATCCAGAAGCCCTTTTCTCCATGGCCTTTCCAGATAATCAGCGTCCACTGCTGAAGACAGACATGGAACGTC
+
@CCFFDFFHFHFHIJJJIGFEGEFFEGFCGHIGIGIJGIIGIIGGIIJJJJIJJIJJIIJGGIIIIGGHG@AHEHGGFDFFFFECCEECC@BDDCDDDDBD
@2ND
TACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACT
+
<<:DAAB=DDD10122+A11?EEI98DDB6D3BAD39?B?D<DE2=BB77;.==C@==CC;93'3<AAAA??(5<>>>??>A?AA>44:>:4((33:>>A3
@2NE
GAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJGHIJJJJHIJJJHHHHHHFFFFFEEEEEDDDDDDDDDDDDDDDDDDDDDD
@2NF
GAGAAATCATAAAGACAGCCAGTTCGAAACTGATATAGTACAACGAATGGAACAAGAAACACAAAGAAAGTTAGAACAACTCCGGGCAGAGCTGGATG
+
CCCFFFFFHHHHHIJJJJIJJJHIIJJJJJJJJJJJJJIIJJJJJIIIJJJJIJJJJJJIJJJIIIIHHHFHFFFFFFEDEEEDDDDDDDDDDDDBDD
@2NG
TTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGTAGCAGC
+
<?;;DDDD8C<AB3AAFEEHE@GIBEH;BF@FFFGEGBC>GFIFEG:DFFBFF;@FGFECF<C()?7A@>BB>BC6;@A>@B;?BB<2?A;>A?BA1:>32
@2NH
CCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGC
+
CCCFFFDEHHHHGGIJJJJJJJJJJJJJJJJJJHJJJJJJJJJJJJJJJJJIJJJIJJJJJJJIIHHHHHHFFFFFFCEEDDDDDDDDDEEEDDEDEDDDD
@2NI
ATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCC
+
@C@FFADDFFACDHIIIDCIIIIIIIEIIIDHGEG@CCGGIIIIHEH?FGFAHG@FGHCGDHIIG7;@)==CEFCCF;7?CC;@@;>?ABB:@A>CC>>AB
@2NJ
GGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCC
+
?@@DDFDFGHGHHGIJJI@HGIGIIJGGEHGIJIDEIGIGIJJJIIGIIII@B@HHHHFFFF@CCEEECCDDEDDDDDDDCDCCDDDDEDDCCDDDDDDD
@2NK
AGAAATACTTATAGAGGAAAATGAGGACCTCAAACAACAATGTATTCAGCTAAATGAAGAGATTGAAAAGCAAAGGAACACTTTTTCATTTGCTGAAAAA
+
CCBFFFFFHHHHHIJJJJJIHJJFGIAGCHGHHIIJJIIGJJHIJJJIIHIHIIHJGHGAHGGIIGJIJJIIJJJGHHGFFFFDFECCEFEEDDDCCDDD
@2NL
CAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGG
+
@@@DDEFFFHFFHGGIFHIIACFHIJIJIGIJJIGIGCGHIIJJJJEGGGIHGGIIGGGDIGHHCEBDDFFECCEECAC@@CDDDBDDDDD?BBBBCCCDD
@2NM
TTTGCTTTTTTTATTCTCTTCCACTTCCTCTTTCCTTTTGTGCTTTTCTTTTTTCTTTTCCTTCTTGTCTTTCTCCTTTTTCTTTGGTTTGTTCTGCTG
+
CCCFFFFFHHHHHJJJJJJJJIJJJIHGIJJJJIIHIJJJHIGHIJJIJJJIJJGHIJJHHIGGHHFHFEHFBCEDEEEEE@EDDCCBDD?BDCDCCDD
@2NN
TGTGCATATAAACACAATAGAACCTGTCAATATTGATGACTTGATTAGAGACCAAGGATTTCGTGGTGATGGAGGATCAACCACAGGTTTGTCTGCTAC
+
CCBFFFFFHHHHHJJJJJJJJJJJJJHJJJJJJJJGJJJJJJJIJJJIJJIJJJJIJIJJJJJGHI@FHGIJJJHHHHFFFFDDDEDCDDDDDDDDDDD
@2NO
TGAAGCTCAGTCTCTGAAAGATGAGATCGACGTGCTGAGACATTCTTCTGATAAAGTATCTAAACTAGAAGGTCAAGTAGAATCTTATAAAAAGAAGCT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJHIJJJJJJJJJJJJJJJJIJJJJJFHJJJJJJJJJJIJJJHHHHHEDFFFFFEEEEDEEEDDDDDDD
@2NP
CCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACT
+
@@;BDDADBHB?BB@FAG<?CFHEHGGGEEEEGIIGGIGHHGIIICB>GH@FHGHIFDHGDDACEEHHFBB7?@@CCDCCCCCECCCCBBBB?ACCCBC83
@2NQ
TAACTAACGTGAAAGCCTTACAGAAATCTCCAGGACCTCAGCGAGAAAGGAAGTCATCTTCATCCTCAGAAGACAGGAATCGAATGAAAACACTTGGT
+
@<?DDDD??<DFFIBBB:AGG<<2<22A2???EC;?FGB?F<?60.@B8(....888@7=E@EFI;777.7..)..,>BC>;;(-55>@@55?BA::+
@2NR
TTGCAATCTCTGAAGATCATGTGGCCTCAGTGAAAAAATCAGTCTCAAGTAAAGGCCAACCAAGCCCTCGAGCAGTTATTCCCATGTCCTGTATAACCAAT
+
CCCFFFFFHHHHFJJJJJJJJIJJJJJJJJHHHJJJJJIJJJJJJJJJJGHIIJGGIJJJIJIJJJJHHHFFFDECEEEDDEDDDDEDEDDDDEEFDDDDD
@2NS
AGAGATTGAAAAGCAAAGGAACACTTTTTCATTTGCTGAAAAAAACTTTGAAGTTAACTATCAAGAGTTACAAGAGGAGTATGCTTGCCTTCTCAAAGTA
+
@@CFFFFFHHHGHJJJJIJJJJIJJJJJJGIJJJJIIJJJJJJGIJIJJJJJJHGIIIIJIGIJIJHFEHHHFFFFFECCCEEDEEDDDDDDDDEDDDAC
@2NT
GAGATCCCTTGGCCTTAATTGAGGAGCTAGAGCAAGAAGAAGGACTCACTCTTGCCCAGCTGGTCCAGAAGCGACTCATGGCCTTGGAAGAGGAGGA
+
@@@DD??D<FB?FGGGHHHEIG@E9@BAA<*?FB)CC99DBBB8?FGIACDBB?/=<=F>AH>=FHDGA;=?=(9ACACA@?ACAA:(5,<?<9?5@
@2NU
CCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGATATGGGCAACA
+
===A1+<<A=2++2)<?=@AAB+:?**1?3*7?7?AB=A>A>A77*0=9=/=(9>7=)8.)-.6:A',35((53(((5;193,,((,((,5(3(((3;9(
@2NV
CTGCAGTTTTGGTAACTTTTGGTATTAATTTGGGTGTTGAAGGTATTTTCGACAATTTATTACGGC
+
CCCFFFEFHHHHHJJJJJJJJJCHHIIJJJJJJJEHIHIJJJJBGHIJJJJJJJJJJJJJJJIJJH
@2NW
GATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCACGGATATGCACAGACCACCCAGGCATATGGGC
+
CCCFFFFFHHHHHIIJIJJJFJJJIJJJIIIJJJJJJJJJJJJJIIJJJJJJJJIJHHFFFFDDDDDDDDDDDDDDDEDDDDDDDDDDBDDDDDDDEDDD
@2NX
AGACAGAAGAAGCTGGAGGCCGGCAAAGCCAAGCTTGCCCAGTTTCGACAAAGAAAAGCTCAGTCGGATGGGCAGAGTCCTTCCAAGAAGCAGAAAAAAA
+
CCCFFDFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHIJJJIJJJHHHHFFFFFEEEEEDDDDDDDDDDDDCCDDDDDDDDDDDCDDDDDDDDD
@2NY
CTGCAGTTCAGAGGTAAATGGTTGCAGTTTTGTGATGAGAACAGGAAAGCCTACAAATTTATTAAGGGAAGAAGAATTTGGTGTTGATGATTCTTATTCTG
+
CCCFFFEFHHHHHJEGIJIJJIHIJIHHHJIJHIIJJIJHIIJJIJJJJJJJIJJJJJJJIJJJJJJJJJJHIHGHHHHFF?DDDDEEDEEEEDEDDEEFE
@2NZ
CTGCAAGTGGCTGTGAAGACGCTGCCTGAAGTGTGCTCTGAACAGGACGAACTGGATTTCCTCATGGAAGCCCTGATCATCAGCAAATTCAACCACCAGA
+
CCCFFFFFHHHHHIIJJJIJJJJJJJJJJJJFHGIIJJJIIJJJIIIJJJ@@@FHHIJJJHHHHHHFFFDDDDEEDDDEDDDDDDDDDDDDEDDDDDDDD
@2O0
CCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTAT
+
@@@FFFDDHHHHGGIIIHIHJJIJJHHIIIIJIJFGEGIEHIJJIJJIIIGHHFEBDCFEEEEEDDCEDCDDDDCDDDBDDDBDDCDCDDDDB@DDCDCDD
@2O1
CTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGC
+
CCCFFFFFHHGHGJJJJIJIIJJJJIJJJJIIJJIIIJIJJIIJJJJJJIIJJJJJJJJJJJJJJHHFHCFFFFFEEEEEEEDDDDDDBDDDDDDDDDDD
@2O2
CAGGAAAGCCTACAAATTTATTAAGGGAAGAAGAATTTGGTGTTGATGATTCTTATTCTGAACAAGGAGCACAAGACAGTCCGACTCATCTAGAGATGATG
+
;;1ADDB;BB<DFBFBGGF4CFDHEFG@GB?@?GFE@>F>):FGIIFIIEF<D?DFB8==CFFFFCFIF@DEEF;7);?B?D=B;;8;>>>:@BAA@>:BB
@2O3
ATTTCGCCGCCAGCTTTCTGAACCCTGTAACTCCTTTCCTCCTTTGCCGACGATGCCAAGGGAAGGACGTCCTATGTACCAACGCCAGATGTCTGAGCCA
+
@@@DDBDFGGGDHHIBFHIGGIHGGIIEHHI<BFGDGHIIII@@<BFFEHIIBBDDBECBBBBBBC?A88=BBCCC>BBC@CB<<@BBACCCCDCCCCAC
@2O4
CCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCG
+
@@@DDDDDHHADFBFHE?CHEEHGHIIIG@B@GGHIIADHIIIGB;?DG;DGF>CBGIG=FDCC@GDHFEAB?DEB>6;;?AB=C@AC>AC:>>A@CCCCB
@2O5
ATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCA
+
CCCFFFFFHHHHHJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJHIJJJJJJJJIJJHHFFFFDDDEDDDDDDDDDDEDDDDDDDDDDDDDDDDDDEDDDD
@2O6
CTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATG
+
CCCFFEFFHHHHHJJJIIHJJIJJJJIIJJJJJGHIJJJJJJJIJJJJJJHHHHFFFFFEEEEDDDEDDDDDDDDDDDDDDDDDDEDDDDDDDDDDDDDDD
@2O7
CTGTGTTGTCCCAGAAAAATTCGATGGAGACATCAAACAAGAGCCAGGAATGTATCGGGAAGGACCCACATACCAACGGCGAGGATCACTTCAGCTCTGGC
+
@@@DDDFFHDCDHGIJJJJGGEGFHHBG>BCGHGGGEGHIIHIDGGHGEHAEBFCGCFGGEDCEEFFFE?>CCCDDBB=?BB<9039<?AC@C@>A>AACC
@2O8
AACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACC
+
@@@FFFFFHGHHHJIJJJJJJJJJIJJJJJJJIIIJJJIJJJIIJIGGIIIJJGHHHFFFFEEDEDDDDDDDCDBCCCCDDCCCDDDDDDDDDDDDDCDCD
@2O9
CTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGC
+
@C@FFFFFHGHHHJJJIJJJJJJJJJJJJJJIIHGIJJJGIIIIIJJJJHIJJJIJJJIJJJJJJIJHHHHHFFFFEEDDEDDDDDDDDDDDDDDDDDDDD
@2OA
CTATGATAAACTTAGCCGTTCACTCCGCTATTACTATGAGAAAGGAATTATGCAAAAGGTGGCTGGAGAGAGATATGTCTACAAGTTTGTGTGTGATCC
+
CCCFFFFFHGHHHIJIJJJJJJJJJJJJJIJJJJJJJJJJIJJJIJJIJJIJJJJJJJJGIJJIJJHHHHEFDFEEDFEEEDDDDDDEDBDCDBDDEED
@2OB
GCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGC
+
@@@DFFFFHHHGG@EHIICGHAGGCFFHGDHGI>DFFFDFEGBGHIIIIIDGIGIEGHHIIIIIGHHFFFFFFEEACACCCCCCCCCACCCDCBCCCCCCC
@2OC
TATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGC
+
CCCFFFFFHHHHHJJJJJJJHJJJJJJJJJJJJJJJJJJJJJJJIIJJJJJJIJJJHHHHFCFFDEEDD;@DDDDDDDDD:ACDDDDDDEEDDDDDDDDDD
@2OD
CTGGATTTTTCAAAAGCAGATTCAGGTGTTCATTTATGTGTTATTGATGACTCCAATGAGCATATGCTTACTGTATGGGACTGGCAGAGGAAAGCAAAAGT
+
CCCFFFFFHHHHHJJJJJJJJJIJJJCFHHJJJJJJJJEGHGIJJJJGIIJJJJJJJJJIJJIJJJIJJJJJJFHIJIJGGEEHFDEFFDCDEDDDDDDD>
@2OE
TGATGACATCTCCTGTGACTCTCACCTCTCAGACAACTAAGACAGATGACCCCCAATTGAAAAGAGAAATAAGGTTAATGAAAAACAGAGAAGCTGCTCG
+
CCCFFFFFHHHHHJJHJJJJJJJJJJJJJJJIIJJJJJJJJJJIIJIIJJIIJJJJJJJIIJJJGIIJHHHHHH@EFFFFFEEEEDDDDDDDDDDDDDDD
@2OF
GAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTC
+
CCCFFFFFHHHHHJJJJIJJJJJJIJJIHIJJJJJIJJJJJJIIJJJJIJIJHHHHHFFFFFEDDDDDDDDDDDDDDDCDDEDDDDDDBDDDDDDDDDDDD
@2OG
CTTTGGACTCGCCAGAGACATCTATAAAAATGATTACTATAGAAAGAGAGGGGAAGGCCTGCTCCCAGTTCGGTGGATGGCTCCAGAAAGTTTGATGGATG
+
<@@FFFFFHFGGHIJIJJJJJJJJJJJJJGIIGIIGGIIIJJJFBHHIBDHIIEHIGGIIGHGHFFFFFDECDB@>ADCBDCABDDDDDCCDEDDDDDDDD
@2OH
GCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGC
+
CCCFFEFFHHHHHJJJIJJJJJIJJJJIIJJJJJJJJJJJJJJJIJIIJIJJJJJJJIJIJJIJFHHGHFHFFFFFEECCCEEDDCDDDDDDDDDDDDDDD
@2OI
TGCAAATACCATAATTACATGCGGTAAATCTCATATTTTCTTCTGGAACTGGAGCGGCAATTCACTAACAAGAAAACAGGGAATTTTTGGGAAATATGAA
+
;@?BDDBDDB?FD>@E<E@@BDF<?FGGH99C?CCDFD<@DHGHBB@*0?<;3B;6@AAH>;=?EEEEB7?@CCCA9A==5<??CCCCB858?BCCD@CD
@2OJ
GCTGAGCTCCAGGAGCAGCTCAAAGCCGTGCACGAGCAGCTTGCAGCCCTCTCTCAGCCCCAGCAGAACAAACCAAAGAAAAAGGAGAAAGACAAGAAGG
+
CCCFFFFFHHHHGJIJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJIIJJJJJJHHHFFFFEEEEEDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDD
@2OK
CAGTTACAAGCCTTCAAAAATGAAGTAGGAGTACTCAGGAAAACACGACATGTGAATATCCTACTCTTCATGGGCTATTCCACAAAGCCACAACTGGCTAT
+
=?===?AB4D3:CABFBDF;BC:FE<@FHHGI@C9?9*3:C?FF;??D:(<B==F)B=F7)8===)@D=DHHFE9CED?B;;;@?>((5,(9??>5?995>
@2OL
CGGGAAGGACCCACATACCAACGGCGAGGATCACTTCAGCTCTGGCAGTTTTTGGTAGCTCTTCTGGATGACCCTTCAAATTCTCATTTTATTGCCTGGAC
+
CCCFFFFFHHHHHJJJJJJJJJJJIJJIJIJJJJJJJJJJJJJHHHHFFFFFFDDBDDDDDDDDDDDCDDDDDDDDDDDDDDDEDEEEEEEDDDDDDDDDD
@2OM
GAGCGGGTCAGGCTCAGCGTCGGCCACTCTGTCGGTCCGCTGAATGAAGTGCCCGCCCCTCTAAGCCCGGAGCCCGGCGCTTTCCCCGCAAGATGGACGGT
+
CCCFFFFFHHHGHJJJJJJJJJJIIJJJJJJJJIJIJIHHHFFFEEEEEACDDDDDDDDDDDDDDDDDDDDDBBBDDDDDDDDDDDDDDDDDCCCDCDDD>
@2ON
AACAAGTTTCATTGAGATGTAGAGAGCTAGAAATCATTATTAACCACAACAGGGCAGAAAATGTACAGTCATGTGATACTCAAGTAAGCTCTTTATT
+
CCCFFFFFHHHHHJFHIJJJJJJJIJJJJJJJJJJJJJJJJJIJJJJJJIJJJJJJJJJJJJJIJJJJJJJJJHJHHHHHHHFFCFFFDEEEEEDDD
@2OO
CAAACAGAGGATTTTAGTCTATATGCTTGTGCTTCTCCAAAAACACCCATCCAGGCAGGGGGATATGGTGCGTTTCCTGTCCACTGAAACAAATGAGTG
+
@@@FDFFFDFADDFGGGHGIEHICIFHHHEFHIIIIIIIIHIIHIIIIIHE>FGIHGIIFIHDBCEED;ACBDBDCDDDDDDDCDDDDDDDDDDDDCCC
@2OP
GCTGAGCTCCAGGAGCAGCTCAAAGCCGTGCACGAGCAGCTTGCAGCCCTCTCTCAGCCCCAGCAGAACAAACCAAAGAAAAAGGAGAAAGACAAGAAGG
+
CCCFFFFFGHHGHGIJJJJJJIJJGIJIJDIJJJJJJJJJJJIIJJJJJJJJJJJIJHHHFFFFDEDEEDDDDDDDDDDDDDDDDDDDDDDDDDDDCDDD
@2OQ
GATCATCAGCAAATTCAACCACCAGAACATTGTTCGCTGCATTGGGGTGAGCCTGCAATCCCTGCCCCGGTTCATCCTGCTGGAGCTCATGGCGGGGGGGG
+
@@<DFFFFGGHGHJJIJIJIJJJGIJIJIJGHIJJJIBGHIIIJJJJ@AFGIJIJJJJJHGFHHFFEFDD9?BDEEDDCCDDD@DDDDDACDBDD5>@B<>
@2OR
GTGGCAATAAATGAACTGAATATAAAATTGCAAGATACTAACTCTCAAAAGGAAAAACTCAAGGAAGAACTAGGACTAATTTTAGAAGAAAAG
+
BB@FFFFFHHHHGJJJJJJJJJJJJJJJJJIJJIJJJJJJJJJJGIGIJIIEIIJJJJIIIJIEIJJJJJIGCEIFFHHHFFFFFFFEEEEEC
@2OS
GGTCGTTGGGCATTCCGGACACCTGGCCTTCATACACCTCCCCAAAGGCGCCATGGCCCAGACCCCGAATGAGGGTGATGTTTTTCCGCGGCACCTCCTTC
+
BCBFFFFFGDDHHIJJJIIJJJJJJIJJJJJGIIJIJJJJJJIJJJIIIIJHHGHFFFFDDDDDDDDDDDDCDDD8?BDDCDEDBDDBDDDDBDDDDDCDD
@2OT
ATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCA
+
CCCFDFBDFFHHA@FGHGHCFHIGDHCHGGA>FEGGGBHIIGG9?BGCEHIGIIIIHA?BFE6;@@ACDDDCDADC<@CC?B?9?B<8<BBBCC>>>AB?
@2OU
CTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCT
+
CCCFFDFFGHHHHJJJJJJJJJJJIJJJIJJJJJJJJJJJJJIJHJIJJJHIIJJJJJJJJJHHHFEFFEEDDEDDDDDEEDDDDDDDDDDDDDDDDDDDD
@2OV
CAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGAC
+
?<@DDDDDH?:F?EEE@GI<HDHD@GBGGGE>?:?DGBFHGH<D?D@D;FADHGGGGCFHGC@DE@CGIHHFFA8;BC@@BB8AAA>@CCCC@C>C>@AA
@2OW
AGATATTGCACGACAGACTGCACAGGGCATGGATTACTTACACGCCAAGTCAATCATCCACAGAGACCTCAAGAGTAATAATATATTTCTTCATGAAGACC
+
@@@FDDEDDDDHFDG<GFHJGGIGHGC@CFBAA@FHGEDFHG@FGDAABHGDHC@HHGDH@HEFEBEDF>CEACA6>C>@CDE>ABDC;@A@ADCCDDDDD
@2OX
GGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACTACCACTGCTACAGTCACCACCACCC
+
@@@DFFDDHHHHHFIIIG@EEHGIIIDDCEIGIIIIIGIIGGIIGGHIIID;BEA@HF@DDFBCCECCACCDCCCCCCCCCCACC:A>CC>CCCCBCB@@
@2OY
CAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGC
+
CCCFFFFFHHHHHJJJJJJGHIIJJJJJJJDFHIIIJJIIIJJJJIJJJJJJJJJJJJJJJJJJJHHHFFFFDEEDEDDDDEDDDDDDDDDDDDDDDEDD
@2OZ
CAACGTACGGCTCCTGGGTTACAGAGAAACCCACCAAAAAGAATAATCCTATAGCAAAGAAGGAGCCACACGACAGGGGAAACCTGGGGCTGGAGGGA
+
=1122?+AC=A0A<+@3+2@+*@=17):::))):0)0//=:7A<788ABA7....=ABA>AAA9=@@A3;(',',2;=6&)8(+8888;505;=8090
@2P0
GAGATTGAAGAGCTAAACAGAGAGCTGGAAGAAATGAGGGTTACCTATGGGACTGAAGGACTGCAGCAGTTACAAGAATTTGAAGCTGCCATTAAACAA
+
B@CFFFFFHHHHHJJJJJJIJJJJJJJJJJJJIJJJJJJJIIJJJJJJJJJJIJJJJJJIJJJJJJIHHHHHHFFFFFEEEEEEEDDDDDDDDDDDDDD
@2P1
TGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGC
+
=?14BDDDDDD?DEA9EEEDCEECEDDDEED@DDCDCDCDID@@CBCCEEICEEAEICD@ADCDDDD??=?9=AAAA:A<>?????>>A>>>?;)9>A<?
@2P2
GCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGC
+
<@@DDADDBHHFHG>F;F@GCCHCGEBF>18CGGBDHGGF3DFH@GHIBEHIIBHG2=GHEEAAEHEHECCDCC=1>;>ACC53;>BC(;::AC?@+2>>>
@2P3
GTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGC
+
CBCFFFFFHHHGHIJJJJJJIJJJJJJJJJJJJJIIJGIJJJJJJJJJJJJJJJJIJJJIJJHHHHFFFFFDEEEECCEDDEDEDDDDDDDDDDDDDDDDD
@2P4
AACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCC
+
@@CFFFFFHGDHDGIIJJIJIIGGGIIJJIJBFHJIGIIIHIGIIIIEEGGHHHHAEBCCEFFEFEEEEEDDCDD3>@CCDDD?BDDDDCDDDDDDDDDD
@2P5
TAAAAATCCATACAGCTTTCAGTCAGATGTATATGCATTTGGAATTGTTCTGTATGAATTGATGACTGGACAGTTACCTTATTCAAACATCAACAACAGGG
+
@@@DDDDDHHHHFDFDHGGGII?C?HEHIAFHEHFGIIGIIAFEHIE9BGAF??BFHAHHD>FGGGHIIIFHAHIIIIIIGHGEHFHCHFDDEEEAAA@A(
@2P6
CAGGCCAGCTATGAACTATGATAAACTTAGCCGTTCACTCCGCTATTACTATGAGAAAGGAATTATGCAAAAGGTGGCTGGAGAGAGATATGTCTACAAGT
+
@@@D=AA?FH?C?CEGII@?FDCHB?FCEFHIIED>?GDGIGE@?7?FHDGD8FE.=BF>==F@=@C)@EHA;;..;>@;=;=3;(;8@AA>C>555@:A:
@2P7
CGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGC
+
@C@FFFFFHHHHHJJIIIJJIJJJJJJJJIJJJJJGJIJJJJJIIJIJIJJJGHIJHHHHHHFFDDDDDDDDDDDDDDDDDDDDDEDDDDDDDDDDDDDD
@2P8
AGATATTGCACGACAGACTGCACAGGGCATGGATTACTTACACGCCAAGTCAATCATCCACAGAGACCTCAAGAGTAATAATATATTTCTTCATGAAGACC
+
@@@FDEDDHHFHGJJJGIJGHGGGAGEGIJJIFGIIJJJJJJJCGGAGHHJJJJIGIIIGIHGHEDFFFFEEEEE@CDDE@CDEEEFEFEDDEEDDDDCDD
@2P9
CACCTATGGAAAGCAGCCATGGTTCCAACTCTCAAACACGGAGGTCATTGAGTGCATTACCCAAGGTCGTGTTTTGGAGCGGCCCCGAGTCTGCCCCAA
+
CCCFFFFFGHHHHJJJJJIJJJIJJJJJJIJJJJJJJJJJIJJJBFHIJJJJGHIJJJIJJJJJJHAEHDEFEEEEDDDDDDDDDDDBDBCDDCDDDDD
@2PA
TAATCACTGCCCAGCGTCCTCCGAGTCCCACCCGAAGCCATCCAGCCCCCGGCAGGAGAGCACACGCGCGATCCAGCTGATGCCCAGCCCCATCATGCACC
+
;?;B::DDDDDDD:+)21@;AEE?:1:DED:DD:D@0(B8=BD7.8ACDAD9>6'381<15:???&80&)5&2<>4>>AAA:>A?A8<???>3<>:4:>>A
@2PB
CAGAACCCTCCTTGAATCGGGCTGGTTTCCAAACAGAGGATTTTAGTCTATATGCTTGTGCTTCTCCAAAAACACCCATCCAGGCAGGGGGATATGG
+
@CCFFFFFHHHHHJJJGIIIJIJIIFIIJJJIIIJJJJGJEHIJJIIIIJJJJJICH>FGIJJEGHGHHHFFFFDDDDDDDDDDBABDDDD@BDDDD
@2PC
CCCCATGGACCACAGATTTCGCCGCCAGCTTTCTGAACCCTGTAACTCCTTTCCTCCTTTGCCGACGATGCCAAGGGAAGGACGTCCTATGTACCAACGCC
+
?@<?DADB<DHHHIIGHIEFEGFGEAGHEFHG@FG<?BBFH>FHHGECD>FAFGEGE@EC?7?9?>>BBBBC>>A@BBBB@8<5>B?BCCCDCDC>>@?BB
@2PD
CTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCT
+
CCCFFFFFFGHHHJGJIJIJJIJJIJJBCHHIIIIIIIJJJJIJJIJJJIJIIIIJGGGHHIIGIJEHHHGHFFDDDDDDDDEDDEDEDDDDDD@CDDDDD
@2PE
GGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATC
+
:8++=00ADDB?AC:AE?CFCFFCFFD9B:99FDFBB?9?D8D?FC=CF>4@CCE=E;D@AAEFE56??C>>>@BB@5?B@:<@?:ABBBB>4>>><@BBA
@2PF
GGACGGTTGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATAT
+
@@@DDDDDFFFHDEHHEEC81??GBHEEFEFHII??BDHE@F8BFBC6C@CEHCG/=?9<A>59?59AC>;5>@@CC>ACBBBB@8<@BBB?CCCC>A:AC
@2PG
GTGGTGATGACATCTCCTGTGACTCTCACCTCTCAGACAACTAAGACAGATGACCCCCAATTGAAAAGAGAAATAAGGTTAATGAAAAACAGAGAAGCTGC
+
@@@FDDFFHHHHHJJJJJJHHJJEHIJJJJJJJJJJJJJJJJJJIIJJJJJJJJJJJJJJJJJIJJJJIHHHHHFFFF@DCEDEEEEDDBDDDDDDDDDDD
@2PH
GGCAGGGTGGATCCTGATCTGTCCAAGCCTAAAAACCTTGCTCCTTTACAAGAGAGTCAGGAGTCTTACACAACTGGGACTCCCAAAGCAACATCTTCTC
+
@C@FFFFACFFHHJIJJGIIIJIGHJIJJGGGIJJIGCHGGFHIJJFIIJJEHIIJIGGHEHI@EEAEHHDEFBACEDABDDD@CDD<9CC?BCCCCDCC
@2PI
GCATATGCTTACTGTATGGGACTGGCAGAGGAAAGCAAAAGGAGCAGAAATAAAGACAACAAATGAAGTTGTTTTGGCTGTGGAGTTTCACCCAACAGATG
+
@@@FFFFDFFDHDIDHHIJJIJJJIIJJJIJIGIIIJJGEGIGIGEHGIIJJJIJIIJJEHJIJJJJHEHHHHFFFDCDC;AA5?>?CA@CCDDDBDDDDC
@2PJ
ACTCATCAACAGCAGCTTGAAGAACAAGACCACTTATTAGAAGATTATCAGAAAAAGAAAGAAGACTTCACAATGCAAATTAGTTTCTTGCAAGAGAAAAT
+
@@@DDFFFHFFHHIIJJIGIJGIIIGHDFGHECGIJJJGGGEHJJGIIJJJJJIJJIIIGIJJJIJJIJEGHGHHHHFFFFFF>CEEECECCDCDDDCDDD
@2PK
CTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTAT
+
@@@DDDD?DHHGHIEEBBAFIIIIIIGHGFDGGGIHICD8@7;@FGBDHCDEEEEEEDEFFDEEECCD@DC@@CCCCCDC>CD@<@BDDB@BDDDDDDDCD
@2PL
CTGGAGACTCAGGTGGAGTCATGCTTATATGGAGCAAAACTACTGGAGAGCCCACACCTGGGAAAGGACCTAAAGGTGTATATCAAATCAGCAAACAAATC
+
+=?ADD;DB:2AF:<?3;CFH>F<CCFEHCEC4EEF<DDB<??FF*9?BAB(0BA;@@AD@5(=DAF?CDBDB7@B..;;BBB>AA;(5:@BABBB9?BBB
@2PM
CTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACC
+
BCCFFFFFHHGHHHJGIIIIHGGHGJGGIIJIGIJFIGGIGIIIGIGIICFEGHIFFFHDDEDFFDEECCDCDACCCCABBDDDDBCCDD>ADDDCDDEDD
@2PN
CGAGAACTGGGTGAGGGAGCCTTTGGAAAGGTCTTCCTGGCCGAGTGCTACAACCTCAGCCCGACCAAGGACAAGATGCTTGTGGCTGTGAAGGCCCTGA
+
CCCFFFFFHHHFHIJJJJJJJJJJJIJJJJJHGJJJJJJJJJJIJGHIJJIJJJJJJJHHHHFFDDDDDDDDDDDDDDDDEDDDDDDD<ADC@CBDDBBD
@2PO
GTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACA
+
C@CFFFFFHHHHHJJJJJJJJJJJJJJJIIJIJIIJIJJJJJJJGIJGIJJJJGIIJJJJJJJGIIIHHHHHEFFFEEEDDDDDDDDDDCDDDDDDDDD
@2PP
GTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGC
+
CBCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJIHHHHEEFFFFFEECEEEEDABDDDDDDDDDDDDDDD
@2PQ
AGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAAC
+
<?@DFFDDDHHFHGIIIIIIGAEAGFHGGFHGIIIICGGGIFIDIIIIHHHGHD>DDEEEECEECCCBCCBBBBCBC@CC@CCBBCBBCCBCCCCCACCCC
@2PR
GTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGC
+
@?<DDDDDHHFFHIBEGICHGGGEB?FHIIIIHIEEGIIGIEEGIIIDEHEIEEHHHFDEBDF@CCDECDEACDDCBD>CCDCCBB8<5<C>CBBBCCD
@2PS
CAACACCATGGGCGGCAGTGCCGCCCGCCAACGCTTTCCCCCGCCCCTGAGGATAAAACAATAACCCACTGAGTTTTCACTTGATGCCGAAGCGTCTAGCT
+
;;1(8((2)))((((((()..)((-''5=='(,'(,(9(9;<';,)&+(((+((((+(6((+(+(:+82(5((((++((((((+((5+&)))&&(()+((5
@2PT
CTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTTATGGGC
+
@CCFFFFFHHHGHJJJJIHIJJJJJJJJJJJIJIJJJIGJJJJIJJJJIJJIJJJJJJJJIJHFHHHFDDDEDDDDDDDDD@CDDDEDDD9<>@DDDDDDD
@2PU
CTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTAT
+
CCCFFFFFHHHHHIIJHIJIIIJJIJIJHEHIJJJJJHGJIAGHIIJJJHIHCEHGHEFFFFEECEEDDDDDDCDDDDDDDCDDDDDDDDDBBDDDDDDDD
@2PV
TGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGC
+
@@@DDFDFDFFHHGIDGIJFGIIJJJIJJJJJIGGHJJJGIIIIIIJJJJIJGHGJJJJIJJHGGFDFFFFDEEDECC>CDCADDDDDDCCDDDDDDDDD
@2PW
GCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGC
+
8?<DD>:D:DDDD1<EBAF?A2<8AE?;??C?D<BD@BDEDDDEAB3?D?;CBDCC67A)..7@??3?37?A>>65=(>5;>>,5<A:5>A>=5>A:A>?
@2PX
ACCAGATAGCAGCTACCCCATGGACCACAGATTTCGCCGCCAGCTTTCTGAACCCTGTAACTCCTTTCCTCCTTTGCCGACGATGCCAAGGGAAGGACGTC
+
@@CFFFFFHHHHHJIIIJIIFGEBGGIGEEIGCHHFHAGBF6;CGIIIBFGIIIIGHHHEHDDECDBCACEDCC@CCD?@BD@?B?CC@??B?????ABBB
@2PY
ATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCA
+
CCCFFFFFHHHHHJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJHHFFFFDDEEDDDDDDDDDDEDDDDDDDDDDDDDDDDDDEDDDD
@2PZ
GGAAGATTTAGAAATTGAACATCGAATAAATATTGAAAAACTTAAAGATAATTTAGGCATTCACTATAAACAGCAGATAGATGGTTTACAGAATGAAATG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJIJJJJJJJJJJJJJJIJJIJJJGIIJJIJJHHGFFHFFFFFFCEEEEEDDDD
@2Q0
CGTCCGCACTGCGTGAGCTGGAGCGCTATGTCACCTCCGGTTTGCGGAAGGAAAGGAACCCTGAAGCTGCGAAAGTTGATGGGATTGCCGGCTCCTCCA
+
1+1++)0<))<A8))?AC+1):AB8)?A870:0/0/(/'7'--(7'''',,(.>=;;-(5;=(55;93;(&5;-0;::(8(+88((3;393&&&2((((
@2Q1
GGAAACCTCAAGCTGAGAAAGTTGATGTGATTGCCGGCTCCTCCAAGATGAAGGGCTTCTCGTCCTCAGAGTCGGAGAGCTCCAGTGAGTCCAGCTCCTCT
+
@@;BDBDBH??<CGGBBBACFFHHHCHFHGIIIFBFDH?DBFGDGGGIIIBFE=AGHEIE>DEHHED@DCE>;988>=B<CCC:@@C>C>C@ACCC>CAC@
@2Q2
GGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACT
+
@CCFDDFFGDHHHGIIJJJIJIIJIIDIIIIECHGIIJEGIIJFHGIGIIGIJJJGIIJJJHGHFDDBDDDDDDDDCDDDDDD?CCDDDDDD0<CCDDDDC
@2Q3
CAGGGTGGATCCTGATCTGTCCAAGCCTAAAAACCTTGCTCCTTTACAAGAGAGTCAGGAGTCTTACACAACTGGGACTCCCAAAGCAACATCTTCTCACC
+
@CCFFADDHGHGHJJJJIIIIJJIJJJJJJJJJJJJJJIGIIJJJJJJJJIJIJHIIJIGIGHIJJJJHHHHFFFFBEEDEDCDDDDDDDDDDDDEDDEDD
@2Q4
GACTCAGTGCTGGCAACATCAGCCTGAAGACAGGCCCAACTTTGCCATCATTTTGGAGAGGATTGAATACTGCACCCAGGACCCGGATGTAATCAACACCG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJIIIIIJJJJJJHHHHHHFFFFFDDDDDDD@BBDDCDDEEDDDDDDD
@2Q5
GGTTGCAGGAATTGCTAGACAGAAACTCCCAGGTTGGAGGAGGGCCGTGAGGGAAGCCAAATGCGACGGCTGAAGGGCGGGAGGGGCTGAGAGGAGTGAGG
+
1++22++77+?=7++,2+<+3<++3+2+2+1?)1*?==3?1)=8(7'''-52('.(((...(.('(',3&)&((++5(&)&)0&59&)0(+3+9((+((((
@2Q6
GGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTC
+
CCCFFFFFHFHHHJJJJJIJIIJJIIJJJIJJJJJJJJIJIIJJJJIIJJJJIJJJJIJIIIHHHHHHHFFFFDEDDECDDBDDCDDDDDDBDDDDDDDCC
@2Q7
CTTCAAAAAGAAATTGAAATACTCAGACAAGAAGAAAAAGAAAAGGGTACACTTGAACAAGAAGTTCAAGAATTACAACTTAAAACAGAATTGTTAGAAA
+
@CCDDDDFHHFBDGDEHGIIGIHB@CBFHGGCEEFDCGBDDGGGIII;DD?BFFGIIIIIGIEGCG@GEHHHHHFFFFFFCECACC?C?@CCC>ACCCCC
@2Q8
TGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGC
+
@BCDDEFFHHHHFIJJIIJJJJJJJIJGHIIJJJJJJJJIJJHIGIIIIIJHJIJJJGIIJIIJJIIJJIHHHHHFFFCDEEAEEDDDDDDDDDDDDDDDD
@2Q9
CAATCATTGAAGAATTAAACACAAAAATAATAGAAGAAGAAAAGAAAACTTTTGAGCTAAAGGATAAATTAACAACTGCTGATAAATTACTAGGAGAATT
+
@<?D?BD,=FFFB>FFFEIIF?FG;CFFFFHBFEFFEB:?FBFFFD>??BFEF8?;CBFFEE3(@CFIEICCAEFA>>@?;)7;@@@A>@A@AA@A?@BB
@2QA
CAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGG
+
CCCFFFFFGHGHHJJJJJIJJIJJJJJJJJJJJIJJJJIJIJJJIJJJJJJJJJJJHHHHHHFFFFF)>CEEEEDDDDD@BDDDDDDDBDDDDDDDDDDD
@2QB
AAGACAAGAAGGAAAAGAAAAAAGAAAAGCACAAAAGGAAAGAGGAAGTGGAAGAGAATAAAAAAAGCAAAGCCAAGGAACCTCCTCCTAAAAAGACGA
+
@C@DFFFFGHHGHJGGCIIJJJJJGIIIJJJJJJJGGHJJJIGHIGHJ=FGGIIIGEEHHHHHFDDBDDDDDDDDDDDDDDDDCDCDDDDDCDDBBDDD
@2QC
CACCACGCGGCCCAGCTTCTCGCCGGGGAGCTTGTTGATGTCCAAGCTGAGCTGCCGCTTCTCCTCATAGGACATAGGCTTGCACTTGTCCTCTTCCTCCG
+
CCCFFFFFGHHGGIJJJJJIIJJIIIIJGGDFFFFEDCEEDDEDDCDDDDDDDDDDDDDDDDDCCD>CCDDCDDCCCDDDDDB>CCDDDCCCDCDCDDDDD
@2QD
CAAATGGAGCCTTACAGTTGGCAAGTCCAGGCACAGATGGAGTACAGGGACTTCAGACATTAACCATGACAAATTCAGGCAGTACTCAGCAAGGTACAACT
+
@@@DBA+=2:;BBBAF<AIFFBF@FDEFE9E;?89D@DD<DC*?DB<B60?DDFIG<C>;=@FGIFCE>EE>3?73)773?1>>ADC>A3@??B(5>>A::
@2QE
TGAATGTGACAGCACCTACACCTCAGCAGTTACAAGCCTTCAAAAATGAAGTAGGAGTACTCAGGAAAACACGACATGTGAATATCCTACTCTTCATGGGC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJGIJJIIIIIJJJJJJJJJJJJHHFFDEDEEEEEEFEEDDDDDDDEEDDDD
@2QF
CACGAAGAAGAGCTTTCCAAACTGAAGGAAGATTTAGAAATTGAACATCGAATAAATATTGAAAAACTTAAAGATAATTTAGGCATTCACTATAAACAGC
+
?<@DBDDDF>CFC?CG4EBHGHEHCFGG;9C@BFHCH@GEEEHG@BAEAGEDH@FHIDGIG@CCD@<CGICAHAEEAEDBDEEDCCCCEA>ACCCD;;CB
@2QG
GTTACTCTCAGCAGACCACCTATGGGCAACCGAGCAGCTATGGACCGCAGAGTACCAATGGTCAACAAACCACCTATGGGCAGCAGCCTCCCACCAGCTAC
+
+1=+7AA=ABCB@+2++2?A+7<+2+<2:AA))):0)000*//70.''5''(.7).)7)7).).(6>55(,,,855,5((5,,(++2;<98;=<&8(+(+:
@2QH
CACTCATAGTAGCACAGCTGCAGACTTACTACAAGCCAAACAACAGATCCTCACTCATCAACAGCAGCTTGAAGAACAAGACCACTTATTAGAAGATTATC
+
CCCFFFFFHHHGHJIJJIJIGJJJJJJIIIIJGGIIGIJJJJJIIJIJGJJJJJIIJJJJJJIJJJJJJJHHHHEHFFEFEECCDDDCDEEECDDDDDDDC
@2QI
CTGTGATTCCTGAATCTACAATAATGAGAACTCTACATAGTGGAGAAATAACCAGTCATGAGCAGGGCTTCTCTGTGGAACTGGAAAGTGAAATTTCAACC
+
@C@DFDFFHGFDFGIHIJJGGIIGDGEGAHHEEFHGGIIIHIIIIJJJIHIJJDEBBDBGFHGCDHBFFGHEHEHHHEHHEADBEFFEEEEDE@CCDACAB
@2QJ
GACCGGGCCTTCCCAGCTCACCTCCCTCCATCGCAGTCCATACCAGATAGCAGCTACCCCATGGACCACAGATTTCGCCGCCAGCTTTCTGAACCCTGTA
+
CCCFFFFFHHHHHJJJJJJJJJIJJJJJJJJJJIIIHIJJJJJJIJIJJJJIJJJHHHHHFFFEEEEDDDDDDDDDDDDBDDBBDDDDDDDEDDDDDDDD
@2QK
GGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAAT
+
CCCFFFFFHHGHHJJJJJJJIJIJIJJJHIGJJIJJJJJJJJJIJJJJJJJJJJIJHIIIJJJJJHHHFFFFFDEEEEDDDDDCDDDDBDDDDDDACDCE
@2QL
GCCAGGTGTCCGGAATGCCCAACGACCCAAGCCCCCTGCAAGTGGCTGTGAAGACGCTGCCTGAAGTGTGCTCTGAACAGG
+
CCCFFFDEHHGHHIJJJIJJJJJJJJJJJJIJJJJJIJJJJJHIIIIJEIHHHHHFFFDDEDDDDDCD>CCDDCDDDDDDD
@2QM
TGAAGAGATTGAAAAGCAAAGGAACACTTTTTCATTTGCTGAAAAAAACTTTGAAGTTAACTATCAAGAGTTACAAGAGGAGTATGCTTGCCTTCTCAA
+
@@@DDDDDDHHDA<<C?C;BBE>FGEFDHHGB1*?BBGIICHBHIIE?@CFEGIEH=FGE7@@@;@>ACE=@BE3;;@BB>=5;@D@>CCBCCCACCAA
@2QN
TGGGAAGGCTCTTCAGGAGCCATGTGGGGAGATGACAGAGGTACCCCCATGGCTCAGAGTTATGATCAGAATCCTTCCCCTAGAGCAGCTGGGGAGAGGG
+
=:?;;:D+<:C;DEI<:E?F:<+<FC>1:100:?*9*90??09??B=AD@.7@3777).==.7.?;7;;;AA>AAAA>=;?=9:>>>5=>:<>;??5820
@2QO
GCAGAGTCCTTCCAAGAAGCAGAAAAAAAAGAGAAAAACGTCAAGCAGTAAACATGATGTGTCAGCACACCATGATTTGAATATTGATCAATCACAGTGT
+
CCCFFFFFHHHHHJJJIIJJJJIJJIJJJJJIJIIJJJJJHIJJJJJJJJJHHHHHFFFCFEFEEEEEEDDDDDCDFEDEDDEEEDDEDEDDDDDDDCCD
@2QP
GAAGAATTCCAACCCCGACGAGTTTGAAATCGACTTTGAAACCCTGAAGCCGTCCACACTGCGGGAGCTGGAGCGCTATGTCTCCTCCTGTTTGCGGA
+
;(7@()2):8;9)@/85>@3?4--).<3=7>?7(71)).)<>;?5))6))<':=3;=7=0=>;';;<559<<<<0:(0&(8:(3((8;/6+66(()&&
@2QQ
CGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCG
+
@@@DFFDFGGGDHHAEG@FHHIIFGHIGHEGDHGHGDGGBHIIHIHHBDFFFECFECCEACDCCCCDDB@@ACC=BBBBDBBDDBDDDCDBCDDDCCCCDB
@2QR
CCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTGAGTTGCTAAGAGAGAAAACCAAATAAGA
+
CCCFFFFFHGHHHJJJJJJJJJJJJJJJJIJHHJJJJJJJJJJJJJJJJIJJJJJIJJJIJIIHHGFFFF>CEEEEDDDEDDDDCDBDDDDDDDDDDDDD
@2QS
TTCACTAACAAGAAAACAGGGAATTTTTGGGAAATATGAAAAGCCAAAATTTGTGCAGTGTTTAGCATTCTTGGGGAATGGAGATGTTCTTACTGGAGACT
+
CCCFFFFFHHHHGJJJJJJJJJIJJJJJJJJJJJJIJIJIIHGJIIJJJJJIJBHGII@FGHIIJIJJJGHHHHFFFDCECCBCCCDDEEDDDDDDDDDDD
@2QT
CCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAG
+
=?77DDD2AF??::<EADAC+AEFGDG@GIIIIE::FEGFEGEF@FEFEFIIIAFIIEFFDAAEAEFFFFDDB@DDCCC>>@BB:?=;?BA>@>:+4::
@2QU
ATATGAAATGGAACAAGATAAAAAAGTAGAAAACTCAAATAAAGAAGAAATACAGGAAAAGGAGACAATCATTGAAGAATTAAACACAAAAATAATAGA
+
CCCFFFFFHHHHHJJJJJJJJJJJJJ?FHIJJJJJJJJJJJJJJJJJJJJJJIJJJIJJJJJIIIIHHHHHHFFFFFFDEDEEEDDBDDDDDDDDEEDD
@2QV
TGCTTACTGTATGGGACTGGCAGAGGAAAGCAAAAGGAGCAGAAATAAAGACAACAAATGAAGTTGTTTTGGCTGTGGAGTTTCACCCAACAGATGCAAAT
+
CCCFDBDDHHGHGIJ>GHHJJJJGGIIIJJJJJJJJJCHIIGHGHGCHGGHHJJIJJEGHGGIIDHIHHHHF@CC>AE@BCCDDCDDDDD<@<>CCDDDDC
@2QW
ATCTTCAAGAAAAATTTGCACAACTTGAAGCAGAGAATAGCATTCTTAAAGATGAAAAGAAAACCCTTGAAGACATGTTGAAAATACATACTCCTGTTAGC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJIJJJJIJJJJJJJJJJJJJIHHHHHFFFFFFFEEEEEEDDDDDDDDDD
@2QX
GGCTGTTGGTGTCAGCCAGGAGGGTCCTCCAGGCCTTCCGCCTCAGCCTCCACCACCAGTTGCTCAACTGGTCCCCATTGTGCCCCTGGAAAAAGCTTGGC
+
?;@DFDFF=DHHFHIGHIGFHGFHGHHIGIIDEBFHIDHGHIIIIIIIIIEHGGHIHCCACCEBCFECCAEECCB?CDCCCCCCDBDDBDCDDD9A@CCBA
@2QY
CGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCA
+
1?1A;DDACDDD>;EEAEEE4AEEE?:CDEBD8:DE>DCEACBCAAAC;=CDIDICACAC@@@?/=>>?????AA>::>AA>AAA?9>>>?>><88><A
@2QZ
CAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATG
+
C@CFFFFFHHHHHIIIHGBHGGGJJIJJJGIJIJJJIFGHIHDGIIIIIIGGIHIIIJIJJIGIIIJHHHHFFDBBBCBDCCAACCCDDD?CBACCCDEDD
@2R0
CCTCAAGCTGAGAAAGTTGATGTGATTGCCGGCTCCTCCAAGATGAAGGGCTTCTCGTCCTCAGAGTCGGAGAGCTCCAGTGAGTCCAGCTCCTCTGAC
+
CCCFFFFFHHHHHJJJIIIJJJHJJJJJJJIIJIJIIJJJJIJJJJIJJJJJJIIJIJJJHHHGHH?DEDACBBDDDDDDCDCDDDDDDDDDDDDDDDD
@2R1
ACACGGCATAAGGGAGAAATGGAGAATGCTTTAAGGTCATATTCAAATATTACAGTTAATGAAGATCAGATAAAGTTAATGAATGTGGCAATAAATGAACT
+
CCCFFFFFHHHHHJGHHIJJJJJJJJJJJJJJJJJJGIJJJJJJJJJJJJJJJJJIJJJJJJJIHJJJIJJJHHHHHHHFFFFFFBCEDEEDDCDEECCCD
@2R2
CCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTTCAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTC
+
C@CFDDFDDFHHHEGICEGGEGHIEIC?CEHIIJGFHCHHEGEDGFDGD*BFGBFBFCGHJ9@EHACCEF@DBECEEEACC>@C?>CD>C:@AA>ABCD<C
@2R3
CACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGT
+
C@CFDDDFHHHHHGGIGIGGHEGHGEEHCHIJJGIGJIGIJJEBCGIGGEGG@GE=C=EAEHHGFFD8?B@CACD?8AB?ABBDCDDDCCDCCDDDD?CC>
@2R4
AAAATAATGGTGGAAGATAAAGTTTCTTTTGAAAATATGACTGTTGGAGAAGAAAGTAAGCAAGAACAGTTGATTTTGGATCACTTACCATCTGTAACAA
+
CCCFFFFFHHDHHIIHHIJJIJHIIIJJJJIIJJJJJJJIJIIGHGGGIIJIJJHIHIJIGIJIIJIJJIIIGIJJIHHHGBDFFFFEDEEEEDEEEDDD
@2R5
CGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCG
+
@@@??DDBFBHFF1?CGEDE@C@??DG;GCFHGGDGFHIIIHIHCHEFEBDDCC;>AACC@A;>CCCB@CA9>CC<BBBBBBBB<<BCCC@ACDCC>@C99
@2R6
GTGGTCGTACAAACTGCATCAGGAGATATGCAAACATATTAGATCCGAACTACACCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATGACATCTCCTGT
+
?:?D=B?@AADHHGGGGIIIGHGAFHIGIHBGCGGGHIGIDHGFII=FGGHCBHGHDIF>F>@@GGIFEA>AABDDEECBCC;C?CBCCCDC@CCCCCCCC
@2R7
GGAAAACCACTTCATCCACCGAGACATTGCTGCCAGAAACTGCCTCTTGACCTGTCCAGGCCCTGGAAGAGTGGCCAAGATTGGAGACTTCGGGATGGCCC
+
C@@FFFFDBFDHHIGIIIIIIIIIIIIGIIGEHGGIGAFGGIIDGIIIIHIICH=FHIIIIGIH>=?EFBBCBDBECBDBCCCBCCCBDDCDDDD>BBCCD
@2R8
CAGTTATTCCCATGTCCTGTATAACCAATGGAAGTGGTGCAAACAGAAAACCAAGTCATACCAGTGCTGTCTCAATTGCAGGAAAAGAAACTCTTTCATCT
+
?@C?DBEFGHHFHIHEHGGGFEGIGGIJJJJEHIEGI@EGFHIJJIJJJJGJJII?BGIJIIIIHGHJGGEGIEGIFHHHHHFFFFEDEEEDDDDCDDDDC
@2R9
GGTTATCGAGGAAAGGACTGTAGAGCTAATGTTTACCTTCTTCCGACCGGGGAAATAGTTTATTTCATTGCATCAGTAGTAGTACTATTTAATTATGAGG
+
?<8A?BD==<FD;EG<GG@B3CBE<F@DGC@F4CF??FDHADG9@AEFHIID9?DEC;.6>>6;;>@CCCCCDCCC;@5>;A>@A@@BAC>4:>A@>>+9
@2RA
CAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHIJJJJJJIJHHHHFFFFEEEEEEDDDDDDDDCCDDEDDDDEDDEDDDDDDDACDDDD
@2RB
CTGGAGCGCTATGTCACCTCCTGTTTGCGGAAGAAAAGGAAACCTCAAGCTGAGAAAGTTGATGTGATTGCCGGCGCCTCCAAGATGAAGGGCTTCTCGTC
+
@@@D?BD?6DFDFFGGFFGIBBEHDG9<@A0DHGIIGGFBGGFGFGC;@@@DHH77=A?7=3;;.;@@CC;@A>?/5<<@<<?@?>:>:AC9?8A?:@72<
@2RC
GAAGGATTTCCAGAGGGAGGCCGAGCTGCTCACCAACCTGCAGCATGAGCACATTGTCAAGTTCTATGGAGTGTGCGGCGATGGGGACCCCCTCATCATGG
+
@@@DFFFFHGHFHGJJJGIJJIJJJIJJJJJJJJJJIJJJGHIJIJIJIJJJJJJGEHHHHHFEFFFFFCE>@@CDDDDDB@BDDDDDDDDDDDDDDDDCD
@2RD
CATCACTTAGAGCAACTCAACCAAGTGAAAATGATAAACTTCAGAAAGAACTCAATGTACTTAAATCAGAACAGAATGATTTAAGGCTACAGATGGAAGCC
+
CCCFFFFFHHHGHJJJIJJJJJJJJHIJJJIJJJJHJJIJJJIJGGJJGIJJJJJJIIIJJJJJIJJJJJJJJJJIIIGEHFFHFFFFFCECECEDDDDDD
@2RE
TGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGC
+
@@CFDFFFHHGHGGJIBEGIJIFGGIJIIIJJIJJGDGCHGJIGIGGCHIIIDIHGGEGIJJIHGEHEHEBEDE?BBDCDDDDCBCDDCDDDDDDDDCCDD
@2RF
CAAGGGCCCGCTGCAGTCTGTGCAGGTCTTCGGACGCAAGAAGACAGCGACAGCTGTGGCGCACTGCAAACGCGGCAATGGTCTCATCAAGGTGAACGGGC
+
>=12AAAAA8<701?C7@<=17:7:51?:700?;AA<A:-..7=A775===@9;-555;;=/,0)+(883()&509&533;=?(++(+87:3(+8+8299.
@2RG
CTCTTCACAACCTCTCCAAATACACAGACAAACTCCAGAAAGCAAGAATGCTACTCCCACCAAAAGCATAAAACGACCATCACCAGCTGAAAAGTCACAT
+
CCCFFFFFHHHHHJJJJIJIJJIIJIIJJJJIJJJIJIJJJJJJJJJJJJJJJJJJIIFIJJJIJJIHHHHHHFFFDDDDDDDDDDDDDDDDDDDDEDDD
@2RH
ACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGC
+
CCCFFFFFHHHHGJJJJJJJJJIJJJIJIJJJJJJIJJGIIIJJIJJIJJJJJJIIJJJJHFFFFDEEEEDDDDDDDDDDDDDDDDB5@CDDDDDDDD:AC
@2RI
CCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGT
+
CCCFFFFD=FBAHGIIIIEGIIIHIIIIII>BFHGBGGGGGHHIGI>GGHGBGIGGIIHGIGAEBEDFDDDE@=>@:@ADCDD@=@@DDDDDDDDDDD>
@2RJ
GGAGGGAAAGACAGAAAAATAATTCTGTGGGATCATGATCTGAATCCTGAAAGAGAAATAGAGGTTCCTGATCAGTATGGCACAATCAGAGCTGTAGC
+
@@@DFFFFHHHHHIJGIIGGGGIJGDFHIIIJJJHIIIIIJJIIJGGGHFHHEICAHD@HGIIJIJJIJGEHHHHFDFFDFECEECCCCCDDDDDDDD
@2RK
CCTGGCTCAAGGCAGATCCAGCTGTGGCACTTTATCCTGGAGCTGCTGCGGAAGGAGGAGTACCAGGGCGTCATTGCCTGGCAGGGGGACTACGGGGAATT
+
@??DA>DBDBFABGIBFG>FGEEEACE=?GHIDFEGFDGG??@GFBHICGGH>FH6=A;?7?@BDC;>A??;8?DCC>@@?B?<<@BB50<9?@>BB958>
@2RL
GAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACC
+
CCCFFFFFHHHHHJJJJJIGIJGIEIJGIIGIGIJJGIIJJJJGIHIIGGIGEHHFBDFFDEEDDDEDDDBDDDDDBDDDDBDDDDDDDDDDDEDDDDDD
@2RM
GGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATC
+
CCCFFFFFHHHHHJJJJJJJIJJJJJJJJJJJJJJJJJFHIJJJJJJJJJJJJJJJJJDHHHHHHFEFDEEEEDDDDDDDDDDDDCDDDDDDDDDDDDDDD
@2RN
AAATGACTCTTCAAATCAATGAACTTCAAAAAGAAATTGAAATACTCAGACAAGAAGAAAAAGAAAAGGGTACACTTGAACAAGAAGTTCAAGAATTACA
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJIJIJJJIJJJJJJJJJJJJJJJIJJJJJJJ>EHHHHFFFFFFEDEEEDDEEEDDDDDDDD
@2RO
GAAAAGCACAAAAGGAAAGAGGAAGTGGAAGAGAATAAAAAAAAGCAAAGCCAAGGAACCTCCTCCTAAAAAGACGAAGAAAAATAATAGCAGCAACAGC
+
:+:A1BBDCFDF?@C;CCE>DECE?9?D<C933):?::?9BD:4;FEFE<@9=A=?@?;=;;@@;5=;@>3(8(,8;9@@??BB?ABDB::AAB@B?@1?
@2RP
CTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJIIIIJJJJJJJJJJJJJIJJHHHHHHFFFFDEDDDDDDDDDDDDDDDDDDDDDC
@2RQ
AGACTAGCAGCGGACAGTACATTGCCATTGCCCCAAATGGAGCCTTACAGTTGGCAAGTCCAGGCACAGATGGAGTACAGGGACTTCAGACATTAACCATG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJHJJIJJJJJJJIJJJJJJJHIHHHHHFFFFFDEEEECCDDEDDDDDDDDDDDDDDDDDDDDD
@2RR
CTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAAC
+
C@CFFFFEGHHHHJGGIJIHJJIJIIJIJJIIIGGIAEGGIJJGIIJJJJJJHGHIIGGGFHFC;?BCDDDDBDDDDBBBDDDDBDCDDDDDDDBCCCCDD
@2RS
ACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGT
+
@@@DDDDD:?D:CGBF@DFFCHFIEGIGFF;FFCCA@FFCC9GEE4<BFEIIFFBFFEFEC;@=?<=B4=<??=@?-;5;@>>@B:;9<B<@B?1<5<BB(
@2RT
CTCAGCAAGGTACAACTATTCTTCAGTATGCACAGACCTCTGATGGACAGCAGATACTTGTGCCCAGCAATCAGGTGGTCGTACAAACTGCATCAGG
+
@@@FDADFHHCFHGJIJFHGGHGJJJJJIHJJJIIFEHIJJGGIIJJJJJIJIBHIIGIGI>DHHIGIIGHJJIIHHF:CBBBCBCCBD@CCCCDAC
@2RU
AAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGAC
+
CCCFFFFFHHHHHJJJJJJJIJJJJJJJJJIJJIJJJJJJJJJJJJJJJIJJJIJJJJJJJJJJJJJJJHGHHFFFFDDDDDDDDEDDDCDCDDDCDDD
@2RV
CCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGT
+
@@@FDFFFDHDFHHIJG?HICFDDFIGGHFHIIIJJDHC@DHGIGGBHIIEHH>EECCDDD@DFCDEEEDCB@3;ACCDDDAB@A>CCAD?CDCDDCBDB4
@2RW
GCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGC
+
@?<DDDD?CBF>FGI;;EFGE9CBD;FE?CC;9@CCFBFH;FH?FDDFCGEGHG;@F@@EHE;7=?C?B;?;AC?A>A>;;@CCDCDC@A>>CCCB?A?CC
@2RX
CTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCC
+
CCCFFFFFHHHHHJIJJJJJJJJIIJJJJJJJJJJJJJJJIIIGIJJIJJIJJJJIIJJHHHHHHFFFFFEEECDDDDDBBDDDDDDDDDDDB@CDDDD
@2RY
AAACAGGAACCCAGAGATTTTGCATATGACTCAGAAGTGCCTAGCTGCCACTCCATTTATATGAGGCAAGAAGGCTTCCTGGCTCATCCCAG
+
1==<AA2?7AC=CC=B+<AB@<7ACBBBBBBAA377*1:=ABAABB<9A*9==A==77=ABA>)))-;BA>BAAA>>>>>;>@>@@>=(,;;
@2RZ
GGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACAC
+
@@@FDFFFHDHHHJIJIHJJGHIJIJIGEHFHHJJGCCHIIIJJJJJJIGGJJJIIJGIJIIGGGGIJEHHHHFFFFFDDEEDBDCDDCDDEEDDDCDDC
@2S0
CAATACTGGACCTCCCCCACGGGGGGAATCTACCCCAACCCCAACGTCCCCCGCCATCCTAACACCCACGTGCCTTCACACTTAGGCAGCTACTACTAGA
+
@C@DFFD?BFFDDEE=@FHE@DDF8:BB<@C>@8<A??BBB6<???A@BBD8@B@@@DBCC>(>388<2928?B@C@AC>>?>CCADC@@3:@C>AC:4>
@2S1
GCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACC
+
CCCFFFFFHHHHGJJJIGIIJGHJJJJIJJJJJJJGIJIIJJJHIJIJJIIJJIIJHIIIJJJIJHGGHFFFFECEDFEEDCDDDEDDDDDDDDDDDDDD
@2S2
CAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTG
+
@@@DDADDHBBCFHCDBGHHIHGEGCG;?FHIIGHE@EGGFHIGE=CHGEIGGGGIGHHGF>@DFDFCD2@B?>?>>;ACCDDB<A@CCCCDDBBDBDDC
@2S3
GGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCC
+
=?;D4@DDHHBFBFHIBHEIGGIEBGGIIIGCEHEFGBDBGII@DHIGGGIIIIIBA8.8C:@=@;?EHEEEEDCCC>C@CBBA@A:@>::>>ACBBCCCB
@2S4
ATTTAAAGAAAATTTTAAAAGGAATCTTGGATTATAATCATGAGATTTTAGGACAGCAAATTAATGACTTTACCCTTCCTGATGTGAACCTTATTGGGG
+
CCCFFFFFHHHHHJJJJJJJIIIHJGHGIEGHIJIJJJJJIJJJIIIJJIIIJGHIJJJIJEHIIGJGJIJIIIGGGJFHHHFG>CFFFFEDCEEEDDD
@2S5
TGAAAAGAGAAATAAGGTTAATGAAAAACAGAGAAGCTGCTCGAGAATGTCGCAGAAAGAAGAAAGAATATGTGAAATGCCTGGAAAACCGAGTTGCAGTC
+
@@@DDDBB?3AFCGHGIF?HHIGGECGHDGCE@GGGGEHGFG;FBB@GHDHG(@F@7@D>EHEAHEHE>B@C7ACDC3>;ACCBBCCCC8?B8<8@>C@>?
@2S6
AAAATAATGGTGGAAGATAAAGTTTCTTTTGAAAATATGACTGTTGGAGAAGAAAGTAAGCAAGAACAGTTGATTTTGGATCACTTACCATCTGTAACAA
+
@@@DD>DDDHAFBFEHIIIII@<FFHIGIIIHIIIIIIGGHAGIIIIIIIIIGGGGHHIGIIIIIIECD@4=@@@CGEFFEBEDECECCCCC@CDDDCC@
@2S7
CTCAAGTCCTTCCTCCGAGAGACCCGCCCTCGCCCGAGCCAGCCCTCCTCCCTGGCCATGCTGGACCTTCTGCACGTGGCTCGGGACATTGCCTGTGGCTG
+
@@?BDDBAD?F?AFGHGHGFBGA?GBGIIIE?FHHG6FGAHHEEF?=BEECCCC??BCCCCCCCB@CCCCACCACB8A<9AAB<@&58AC:ACCA:@C@AB
@2S8
CGATACCAAGGGAAGGACGTCCTATCTACCAACGCCAGATGTCTGAGCAAATCATCCCCTTCCCACCACAAGGCTTTAAGCAGGAGGACCACGACCCAGTG
+
:112+0<222<?+2+?<AA<7)1?A**1*1**0)=4=A;*8))8))83)87)77>>B=;=2.7));'.6==5(((,9;>>:=92(2&22(++8&&05188:
@2S9
GGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGC
+
@@<DDFFFGHHGGJIJJIIIGIHIJEIGFHHIGGIJIIIIIEIFGIJGGGIJJGGDGDEIGGEHECEFFBBEDEDEDACACFD@DDDDC?B19>?9CCB
@2SA
CTGCTGGTCGGGCCCAGGATCTGATACGGATCTGGCTGGGGCCGTTGCTCTGTATTCTTACTGATCGTTTGTGCCCCTCCAAGGGGAGGACTTTTGTTG
+
CCCFF?DFGFHFHIGGEHHHEGIIIGGIGFGGA?<DF67@@AGE=EE6?;B@@@CEECDA;:>A>@?<AB8AC@>CBA<??AC@@959>8<CCCC:<98
@2SB
CACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCA
+
CCCFFFFFHHHHHGIJIGJIJJJJEGIIGIJJJIJJJIJJIJJJJIIIIIJJIIJGIJIHFHHHECDFFFFEECECCDDDDDDDDDDCDCDDDCDDDDDC
@2SC
CACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCA
+
CCCFFFFFHHHHHIJJJJJJJGFFGIFGGGGFHIJJJJIJGIIGIIIEIIIJJIJIJJJJHHHHCEFFFFFFEEECDDCDDDCDDDDDDDCDCEDDDDDD
@2SD
GTTTCATTGAGATGTAGAGAGCTAGAAATCATTATTAACCACAACAGGGCAGAAAATGTACAGTCATGTGATACTCAAGTAAGCTCTTTATTAGATGGAGT
+
@@@FFFFFHHHFHGFFHGHIIIIJJIHIEGIIJIIJJJJJJFIJJJIIJJJJFIHGHEFGIGGHIJJJIIIJJJJFGHHEHHFFFFDFECCEDE@ACDAAC
@2SE
CTTGATCGTCAGCTGAAGAAAACTACAGAGGAACTAAATGAAGCTTTGTCAGCAAAGGAAGAAATTGCTCAAAGATGCCATGAACTGGATATGCAGGTTGC
+
CCCFFFFFHHHHGJJHJJJJJJIJJJJJIIJHJJJJIJJJJJJIJJJJIJJJJJJJIJIJJJJJJJJJJJJHHHHHHFFFFFEEEEEEDCEDDDEDD?CDD
@2SF
TCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGC
+
@CCFFFFFHHHHHJJJJJJJJJJJGHIJJJJJJJJJJJJJJJIJIJJJJJJJHHHHHDFFFFFEEEFEEEDDDDDDDCDDDDDDDBDDDDDDDDDDDDDDD
@2SG
TTCAAATTCTCATTTTATTGCCTGGACTGGTCGAGGCATGGAATTTAAACTGATTGAGCCTGAAGAGGTTAGTTTAATAGATTTTAATTAGGACACTC
+
CCCFFEFFFHHHHGHIIJJJIHIJIIIJJJIIIDHIIIIGJGGICBFFGHIIGIHEGHHHGIICEEHE?EEHDDFEEDD@@CDEEDCCDDCCC@CBDD
@2SH
CAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGC
+
@CCFDDFFHHHHHIJJJGJJIJIJJJIJGJIGGGJIGHIJIJJIJJIIGJIHIIGEGGHJIGIGEHIJJHHGH
@2SI
GATCCGAGGAGCAGGCGGGCCTGAGGCCGAGTCAGCTGCGCGGGCCCCCGGATCCCCCGACAGAGCGGCGGCGGGGTCTGGCCCAGGGGGAGGGGCGGGCC
+
;88BDD:@@D?:AA+@)80;65@;3((;4',(;;3>;AA3;?:1::5550:-&0<<<5075&)>9()0&)5&599>09(9<48((+(&0&&)5&59&&&&&
@2SJ
TGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGG
+
+:?1?DDDF?FBF;B;AC<AG+<FEC>>CEFFGBBFDGIEF@GF;FA0-5=C=C=5?ED?=?CB?35=B@ABBA@5::??9:::>>AA::4>A>AABB?8?
@2SK
GCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATAC
+
CCCFFFFFHGHHDIGIICGGGIGIJJJIIHIIGIGDHI@FHEGGHHFHIJJIJGIIIAECHHF?DBFDEBEDCDDDDB?BCD<A>CCCD@ACCDCDCCDDD
@2SL
GCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGC
+
@@@FFFFDDHHHHJIIIEHJHGJIJJJIJJJHIEHHIIIIGIIIJIIJIIBGGHIGGGGIDGIIFHEHEHFFFDFAC@CDCDDDCDCCDDDCDDCACCDD
@2SM
CCTCAGTCCTCACCATGCCTCAGGAGGTCAGGGCAGCCAGAGAGCATCCCACCTGCTCCCTGCTGGAGCAAAAGGCCCCAGCAAACTTCCATATCCTGTTG
+
CCCFFFFFHHHHHJJJJJJJJGIJHIIGIJJJJJJJJJJJJJHIIJJJJJJJJIJJJJJJIIHHHHFFFFFEEEDDDDDDDDDDDDDDDDDEDDDEEDDDD
@2SN
GTAAACTTAAAGCACTTAATGAAGAGCTTCATTTGCAAAGAATAAATCCAACTACAGTGAAAATGAAAAGTTCTGTCTTTGATGAAGACAAAACTTTTGT
+
@?@DBDDDHHFDH@EGE@HHCHHBHHIIIGHCHII4?GGEHGIIIIIGHIEIDGGFGHIIIIIIIIIIG7=FGHGCEEEEGEEHHFF>CEEDACCCCCCA
@2SO
GCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCGGCCCAGCCTAGGATATGG
+
CCCFFFFFHHHHHJJIJGIIJJIIIIIJJIHIIJIIJJJGJIJFJFIIGIGHJGHJGHHHHHHHFFFFFEDDDD@DDDDCDDDDDDDDBBDDDDDDDDDDC
@2SP
CAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGG
+
CCCFFFDFFDHHHIIIJJJJIIJJJIGIGFGIIJGHEGIJIFGGIIIJJJIIJJJJFIIJJGHDDDDDDDDCCCDDBDDDDD@CCDDDDD5<CCCDACDDD
@2SQ
GCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGC
+
CCCFFFFFHHHHHJEHIJJJJJJJIJJJJJJJJJJJJJIJJJIIGIJJJJJJJJIJJJJJJEHIHHFGHHFFFFFDD@EDDDDDDDDDDDDDDDDDDCDD
@2SR
ATTCAGGCAGTACTCAGCAAGGTACAACTATTCTTCAGTATGCACAGACCTCTGATGGACAGCAGATACTTGTGCCCAGCAATCAGGTGGTCGTACAAACT
+
BCCFDFFFHHHHHIJJIIJJJIFHGIIHIGGIJIJIJJGIIEIJJJGGIJJIIIGIJJEHIJIIIIIIJJIIHGHIHHHGFFFFDEDEED;A@;BDDDDDD
@2SS
CTACTTCTCTGCCACAAACTGTGGTGATGACATCTCCTGTGACTCTCACCTCTCAGACAACTAAGACAGATGACCCCCAATTGAAAAGAGAAATAAGGTT
+
CCCFFFFFHHHGGGHIIIJJJIJIFGIIIFHGIJJJJJIIICHIIGIIHHIJJJJIIJIIJJJHGCHGIJJGIJHHHFFFDEDCCEDDBDDDDDDDCDCC
@2ST
CTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTC
+
CCCFFFDDHHHHHGJEEHHGIIIIHIIIJJIIJIHIJIIGIIIIHJJIJIJJJJJIJGIJIEDHHIHEHFDDDDDDDDCDDCDDDBDDDDCCCDDEDDC@C
@2SU
CGGCACTCCGTGGATTTCAAACAGTCCAGGCGCTCCGAGGACGGGCTGCATAGGGAAGGGAAGCCCATCAACCTCTCTCATCGGGAGGACCTGGCTTACAT
+
===+<)?AB<<+<+?BABB??3+<<<1@B>B4:4)0=A:'-(-;6/=973>>>>;3;;;32=(9:5=>8:?9<(8=8??:8;;;;&&)(+2889(387+++
@2SV
CCTGGGGCCCCGGAGAGCAAGTGCAGCCGCGGAGCCCTGTACACAGGCTTTTCCATCCTGGTGACTCTGCTCCTCGCTGGCCAGGCCACCACCGCCTACTT
+
@C@FFFFFHFHDHGHIIIJIGGGIGFIIJJJGGHFFFFEEEEFEDDDDDDDDDDEFDDDDDCDDDCDCDDDDACC@DDDDDDDDDDDDBDDDDDDDDDDDD
@2SW
TAACTGTCCAAAAGCCATGAAGAGATTAATGGCAGAGTGCCTCAAAAAGAAAAGAGATGAGAGACCACTCTTTCCCCAAATTCTCGCCTCTATTGAGCTGC
+
@CCDFDFDFHHHHGGGHIIJJIIIJGHJJ>FHHGICHGGHIJJGGGHIJIJJJGBFHGGGIG;FHGIJGCEEHEFFFFDEECA@ABBBDDDDDEDCCCDDD
@2SX
GATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCC
+
CCCFFFFFGHHHHJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJGIJJJJJJJJJJJJJJJJHEHHHGFFFFFFFEEEDECDDDDDDDDDDDDDDDDDDDDD
@2SY
CGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTAT
+
CCCFFFFFHGHHGJJJJJJIJJJJIIGIJJJJJJJJJJJJIJIIJIIJJJJJJJIEFFFFFFDDDDDDDBDDDDDDDDDDCDCDDBCDCCDCEDDDDDDDE
@2SZ
CCAACCCCGACGAGATTGAAATCGACTTTGAGACCCTGAAGCCGTCCACACTGCGTGAGCTGGAGCGCTATGTCACCTCCTGTTTGCGGAAGAAAAGGAA
+
@@@DADDDA@HHHIGGGGGIIEGHIGBHDGDIGGIJGBFHIIIIAHHHGFF;CE><ABDDACDBB?@@@D;C@DDACCDDCDCA@CCBBDD<ACDDDBBD
@2T0
AGCATCCCCTCAGACCTCACCATGCCTCAGGAGGCCAGGGCAGCCAGAGAGCATCCCACCTGCTCCCTGCTGGAGCAAAAGGCCCCAGAAAACTTCCATAT
+
?=1+=3?BD:8A3+<AE?FA;+AE>+<C<E@9@A)0?:?DD@A?8=CBCD(())=7@CD'.76;;?;(6;;>>9==>?>?><9=?/88(34994>:A::>:
@2T1
GTGAACCTTATTGGGGAGCATTCTGATGCAGCAGAGCTTGGAAGGATGCTTCAGCTCATCTTAGGCTGTGCTGTGAACTGTGAACAGAAGCAAGAGTACAT
+
@C@FFDFFHHHGDIHFIGHIJHJJIGIJIJJJIHGIGFHGFIEHIHIIIJJEIGIAHEDHGIGIIJIE?CCHFC@CCDECCCCEACCDD?>>CCDD>ACDD
@2T2
TAAATATTGAAAAACTTAAAGATAATTTAGGCATTCACTATAAACAGCAGATAGATGGTTTACAGAATGAAATGAGTCAAAAGATAGAAACCATGCAGTTT
+
CCCFFFFFHHHHHJIJJIJJJJJJJJJJIJJJJIJJJJJJJJJJJJJJJJIIIJIJJJIIJJJJJJJIIJJJJJJJHHIIHHHHHFFFFFFEDEEEDDDDE
@2T3
CTCTGAACTTCGGCAACAGAATGATGAACTGACCACTTTGGCAGATGAAGCTCAGTCTCTGAAAGATGAGATCGACGTGCTGAGACATTCTTCTGATAA
+
@@CFFBDDHDAFDEHIIJJDHIIGGEEFHICHIEHEGGIIGEHHAGGHGE@BFGGIGDGGEGGHHHIJGHEHHGFFBBBB?CDDDDCAACCDCDDDDDC
@2T4
CTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTC
+
CCCFFFFFHHHGHJJIIGIHIJGIJIJIGIIJJIIIIJJJIJJJJJJJJJGJHHFHGHCEFDFDFEEEDEDB@CDDCCDDBDBDDDDDDDCDDDDDDDDDD
@2T5
GAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCAC
+
@BBFFFFFHHHHHHIIIJJJJJJJJJIIJIIJJIJIJJGIJJJJJJJJJJJHHHHHFFFFFEEDDDDDDDDDDDDDDDDDDDDDDDDDDDBDDDDDDDDDD
@2T6
ATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTT
+
@@CFFFFFGHHHGHIJJJJJJIJJIJJJIJJIIJJJJJJJJIJIGIJJJJJJJJJJJIJJIJJJJIJHHHHHFFFFFEEEEEDDDDDBBBDDDDDDEDDDD
@2T7
CCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTA
+
???DDDD:ADDDA<8@=<2:?CD3CD3C;)88@D9???DDDBABCEC=AC@C@A>A@C777?CD@???AA>:?<988><2<<3>(3>:4>3+4>A8A9:>
@2T8
GGAAAGGACTGTAGAGCTAATGTTTACCTTCTTCCGACCGGGGAAATAGTTTATTTCATTGCATCAGTAGTAGTACTATTTAATTATGAGGAGAGAACTC
+
CCCFFFFFHGGHHGIIEEHGGIJJGBHGIHEIIGEEGEHIIJBEHGG@DHEHHGHHGFFFFFFFEEECACDDD@CCDAFEEEDCEADDCDDC<?B?CDDD
@2T9
AGCAGATACTTGTGCCCAGCAATCAGGTGGTCGTACAAACTGCATCAGGAGATATGCAAACATATCAGATCCGAACTACACCTTCAGCTACTTCTCTGCC
+
CCCFFFFFHHHHHJJIJJJJJJJJJJJFHIJJIFHIIIIJIJJJIIJEGHGEHIJJJJIJJIGGGIJIIHHHHFFFDCEEDDDDDDDDDDDDDDDDDDDD
@2TA
TTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGC
+
CCCFFFFFHHHHHJJJJEHIIIJJJGJIIIIJCHJIIJJIIIIJJJIJJHEHIIIGHIIJJJJIGGJJJHHHEEFEFFEEEEEEEDDDDDDCCDBCBDDBD
@2TB
CTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCT
+
@CCDDDDDGFFGHGIFAGHIIGIIIGIIIEIJJIIGJIJEGHGIJJIJJIFIIJCHFGIIGIJIGIIGEHGHFFDDDDDDD@DCDEDDCCACCDCDCCDC@
@2TC
CCCCACTGTCTACGAGGTGCATCCGGCTCAGTACTACCCGTCCCCCGTGCCCCAGTACGCCCCGAGGGTCCTGACGCAGGCTTCCAACCCCGTCGTCTGC
+
@@@DDDDDHDDACFH@G<AAECHIBHIBDBB::?BDGFDH@FDFEGG;;AAAEBB@;@?BCBBBBB@7(9?:C4>B90<@5899@>@CBBBBBBBBB?<C
@2TD
GATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCT
+
@<@DBDDADDFBDCEHD>HIGIFEHEHIIIGGIEGHIIFEGGGIIIIIICHIGIIIGIGEHGIIIIDGIE>CA>?CFEFCACCBDCACBD:<ACCCCDCCD
@2TE
GTTGTTTTGGCTGTGGAGTTTCACCCAACAGATGCAAATACCATAATTACATGCGGTAAATCTCATATTTTCTTCTGGACCTGGAGCGGCAATTCACTAAC
+
B@@FFFFFHGHBFGGGGIGIJJIIJJIGIIJHIJJIGGIJJJGJIIIGIJIJIIIJAGIIJIEGGIIGHHGGHHFFFFFFEEEEBDDDBDDDDDDCDCCDC
@2TF
GTTCTGTTGAGGATGAAGATGGGGATGGGCGGCTTCGGCCCTCACCTGGGCTTCAGGGGGCTGGGGGCGCCGCTTGCCTTGGAAAGGTTTCTTCTTCAGG
+
BB@FFFDEHHHHHJJIIJIIIJJJGIIJJJJJJJJJJJJIHHHFFFFEEDDDDDDDDDDDDDDDDDDBDDDDDDDDDDDDDDDDDDD@CCCDDDDDDEDD
@2TG
GGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTT
+
@<@DDADDD?F<FCGFGAHGHGEAFHBFBHG><EEGGHIAHIHIIHCCGF<??:;A@EHIDE?HCEE@CBCDBBBBBBA9ABB=88+:>>CC@?8())29
@2TH
CACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCC
+
CCCFFFFFHHHHHJFHIJJGIJJJJJIGCGHIIJJJJJJIIJAHIJHGIEGGGGHGGHGI@GHHIJGGHEHHHHFFFFFECEECDDDBDDBBDBBDDBDD
@2TI
AGGAGACCAGCCTGGGAAACATTGAGATCCCATCTCTACAAAAACAAAAAAACAAACAAAACAACAAGCAAACAAAAAACAGATGGATGTGATGACACTC
+
=+1<A<AAA3=++2+<<7?+?+22221@AB1=?A?>?70?=<A=42=>(04:6ABAAA=6.6.2(..,(;;;,592===;83+388(38(++(38(3859
@2TJ
GTGTTCACACTTTGTCAGATGAGAAATGGGATGTTATTAACTGGAGGAGGGAAAGACAGAAAAATAATTCTGTGGGATCATGATCTGAATCCTGAAAG
+
@?@FFFDDB>;FFGEFFGBIGE+<CCD9FEEHIGG@EG<?CGHG@G<;DFGFCGF@HF>FEHHIBEEEEA?>?C98?B=;6>AACCCCCCCCCCCCCC
@2TK
GGCAGAGTGCCTCAAAAAGAAAAGAGATGAGAGACCACTCTTTCCCCAAATTCTCGCCTCTATTGAGCTGCTGGCCCGCTCATTGCCAAAAATTCACCGC
+
CCCFFFFDHHHHHJJJJJJJJJJJIJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHHHHFFFFDEDDDDDDDEDDDDDDDDDDDDDDDD
@2TL
CTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTC
+
CCCFFFFFHHHHGIIEHGIIGIJJHIHIIIIJCHIIJJIJIJJJGJIJGGIJIIJJGIIJGIJIIJJHHHFFFCDCEEDCDDDDDDDDDDCDDDDDCDDAC
@2TM
CACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAAT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJIJJJJJJJJJJJJIJJJJHHFFDDEDEDDDDDDDDDDDDDDDDDDDDDDEDDDDDDDD
@2TN
CAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGC
+
@@@DFD?DBDDFDFHJIJGGHII@FGEHIIJEIIIJJIJJIIIGHGD@AIICHHGGIIJIIIJIEAEAHHHEB?DCDDEECCECAAB??3?B@?B>BBC@C
@2TO
CTGGCTTACATGAACCACATCATGGTCTCTGTCTCCCCGCCTGAAGAGCACGCCATGCCCATTGGGAGAATAGCAGACTGTAGACTGCTTTGGGATTACGT
+
@@@DDFFFHHGHHIJJJJIIIIABEEEHGJJJJGGIJJGIIJJIJGIIJGIIJJGHIIJIHHHHHF?BCEEDCCCACDDDCDCEDDDCDDDDDDDDDDDD8
@2TP
CACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCC
+
@@@DDDAD>FHB?B:<C>CHCGEFEGBF=;EAHHEHIIIII@9DA@?DHCEHEGGGGG@GGGGEGHDGFEEEEE@;;>BACC>6;?=;??<A?BB@C528
@2TQ
CACTGCATCATGCATCTCCAAACTCAACTCATACACCGAAACCTGACCGGGCCTTCCCAGCTCACCTCCCTCCATCGCAGTCCATACCAGATAGCAGCTAC
+
CCCFFFFDHFFHFIIGHIIIIIEHHIIGIIGIIIIIGIHIIIIIIIGHGIIIIIHGHHEFB>CEECCDDDC?BDDC?BB@?CCDEDD?@CBCCDDDDDCCC
@2TR
CAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTT
+
@@@FFFFFHHHGHIGIIIGIJJIIIIJJIIJJIGGIJJJJJJJGHJIJIIEGHIGGJJJJIJGFEHHFHF@DFDEAEEEC>CCCDDBDDCCCCCDDDDDD
@2TS
GCTCGTAGCTTTGTAGCATTCTTACCCAGGAGTTTTGTGGTTGACCAACCACACAAAAAAAGTCACTTTTTAATTTTATTTATTATTTCTCCTCTTAGACC
+
CCCFFFFFHHHHHIJJJJJJJJJJJJJJJJJJIIJJJHIJIJJJJJJJJJJJJJJJJJJHFFAEEEEEEDDDDDEEDEDDEDFDEEFEEEDDDDDDDDDDD
@2TT
CTTAGCCGTTCACTCCGCTATTACTATGAGAAAGGAATTATGCAAAAGGTGGCTGGAGAGAGATATGTCTACAAGTTTGTGTGTGATCCAGAAGCCCTTTT
+
CCCFFFFFHGDDHIIIIIFGIJIJIIJGIIIJJJJGIJIIIIJJJIJEHDGGHGHIFDGEHCHHEHHADDFFFFEAEDC@CABABDEC@CACDDDDDCDDD
@2TU
CACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACC
+
?@<:==:ACF?F?A:+::AFD<:A<:2<DAF63BFD@<D<=FFI?)=8=C@)7/A55=);6??;>A(6@;@@>;-(;@@>>?@955@BAA:>(:4>@3<?
@2TV
CAGAGGACCCCCAGGCCATCCGTGGATAATGTGCACCATAACCCTCCCACCATTGAACTGTTGCACCGCTCCAGGTCACCTATCACGACAAATCACCGGCC
+
?@?BDBDDAF?CFHGGGDGGIH?BGBFHFHF?9*???BBFHDH9BFCEHIIEADGGIECA=AECECBB<ABBCCC::AACCCCCCCB89BBCCCCC?@BBB
@2TW
CAGGAACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTACTTATGATCAGAGC
+
5;1((8;@)(((2(<=?<76=?>7)=.>@(9)19:>1)9=?<>>9:>>1=???);=7=??5)6=3>=?=??>:;69803=/;;;'((,,:;2(5286(8
@2TX
CTTGGAGCAAAAGCCCACTGACGCTCTAACGAAAGATGATTTTTGGATCCCAGAAACAAGTTTCATACTTACTATTATAGTTGGAATATTTCTGGTTGTT
+
;;;(()))2@>):2@(.8.2)<-=(<()).1((<(0.03.0.<>/'.9)):>?())<3>0.)))<.9)=;3=3(..:(36.:=>0;1;5;:=(:0,,532
@2TY
GCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGC
+
CCCFDDDFHDAFHGGGEFHIEHGGGGDHGIECHGIGCHIIJG@GBFFCGGHDH@AEHGGEFFDDC>??A<@B?B?CACDCDACCCACCDD?ABC@?B@?<
@2TZ
AGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACT
+
?@=DDDDDFA<BA:AC@BFGF<?DBDGDEEGFCGECGFAF?BDFAFACCF==;;=FEI>EIFFECEFDB;=@>@AB=??@BBBBB>;;>AB@@BB<?BBBA
@2U0
CTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTT
+
CCCFFFFFHHHHHJJJJJJJJJJJJIJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJHHHHHHFFFFFFDDDDDDDDDDDDDDDDDDDDEDDD>@@D
@2U1
CTCATCTAGAGATGATGGAAAGTGAGTTGGCTGGGAAGCAGCATGAGATTGAAGAGCTAAACAGAGAGCTGGAAGAAATGAGGGTTACCTATGGGACTGA
+
@@@DDDD4AAFFHEFHEEBBA@<<FEAAF@@F?GHIGGI@DGADFADBFBDHCG:?=FGDHIEA9F3;EGHHFFEBDB?BDCC=5?B>>;ACCCB??B?C
@2U2
CGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCT
+
?<;+:DA3:CBB8E<FD;F;;?A<F9FGHBAB>G>BDAF?;BB9DBF?D9?9D7FH2=CA@1@C>7)?AH:?BBD>A6=@B?AACC@>CCA@CCC8<C124
@2U3
GAAGCTGGGCCGCGTGGTGCACATCATCCAGTCACGGGAGCCCTCCCTGAAGAATTCCAACCCCGACGAGATTGAAATCGACTTTGAGACCCTGAAGCCGT
+
CCCFFFFFHHHHHJIIIGHIJJJJIJJJJJJJJJJJJJIIJJJHHHHFFFFFEEEEEEFDDDDDDDDDDDDDDDDDDDDDDDDDCDCDDDDDDDDDDDDDB
@2U4
CTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTAT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJHHHHHHFFFFEEDEEDDDDDDDDDDDDDDDDDDD
@2U5
CTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTT
+
CCCFFFFFHHHHHJJJJJJJIJJJJJJJJJJJJJJJJJJJJJIIJJJIJJJJJJJJJJJJJJJJHHFFDEEEEDDDDDDDDDDDDDDDDDDDDDDDDDDCC
@2U6
CAGAATGGCTGGCTGGAGGACAGAACGGTCAATAATCAGGTCTGGGGCGCCGCGGGGCAGGAGCGGGACAAAAGTGCAGCCCGAAGGGACAAGGGGGGGGG
+
1112+2<+2+<)++<=7?<1<++1*)11)))******000*/*0)9'--'''''35&))0&(+(0)&)&(((+(((((+((+&&)&)&++(2((+59&00&
@2U7
CTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGATACAGTCACCACCACCCAGGCCTCCTAT
+
?@1ABBDD>DDDHAFEH?E=DFHIIFG9BDFDE00B8B>6A<A>F=C)7C@>?7=;A>@>>>;;@CACA;;;(-5@CC5>CCCC58<8?>BBB<<AAA?34
@2U8
ATGGCAGAGTGCCTCAAAAAGAAAAGAGATGAGAGACCACTCTTTCCCCAAATTCTCGCCTCTATTGAGCTGCTGGCCCGCTCATTGCCAAAAATTCACCG
+
@CCFFFFFGFHHGJJJJJJJJJIIIJJJIJJJJJIJJIJJJIJJJJIJJJJJIIJHJJIJIJIHFHHHHDFEFFEEDEDDDBDDDEDDDDDDDDDDDDDDB
@2U9
CTCAGTAAGGTACGGAGTAACTGTCCAAAAGCCATGAAGAGATTAATGGCAGAGTGCCTCAAAAAGAAAAGAGATGAGAGACCACTCTTTCCCCAAGAGA
+
CCCFFFFFHHFHHJJIJBGIIJJIJJJJJJJJJJJJIJJIJHJJJJJJJJJJIJGHIJJJJJJJJJJJHHHHFFFFFEEEDEDDDDDDDDDDDDDDDDDD
@2UA
TACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCT
+
CCCFFFFFDHHGHJIIIIGGGGIIGEEGIIJIJIGIIJGHCGHCBHGIGIJICHCEE7;BDDEDDEEDC;@CBABCCDDCDA@>ACACCDDDDB<BBDBDD
@2UB
CTACTGTAGAGCCCACACCTGGGAAAGGACCTAAAGGTGTATATCAAATCAGCAAACAAATCAAAGCTCATGATGGCAGTGTGTTCACACTTTGTCAGATG
+
CCCFFFFFHHHGHJJJJJJJJJJJJJJJJJJJJJJJJ?FFGIJJJJJJJJJJJJJJJJJJIJJJJJIIIHHGFHHFFFFDEACBECDDDDDDDDCDEDDDC
@2UC
GGGAGACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTT
+
CCCFFFFFHHHHHIJJJIJJJIIGIJGHJHIIJJJJJJJJJJJIJHHHFFFDDDDDDDDDEEDDDDDDCDDDDDDDDDDDDDDDDDDDDDDDDDDDCCDED
@2UD
AAAAAAAGAAAGAAAAACCACAAGGACAGAGAGAAAAAAAAGAGGAATCTCATTCTAATGATCAAAGTCCACAAATTCGAGCATCACCTTCTCCCCAGCCC
+
CCCFFFFFHHFHHJIIJJJIJJIIIHIGFHGCDBFGHIGIHHBEFE>CECC@DDDEDDEDDDCDDDDCDDDCCBDCDDBCCDDDDDCDDCCDDDDDDDBDD
@2UE
CTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTT
+
@@CFFFFFGHHHGJIIJJJJJJJIJIJJJIJJJIJJJIIJJIGHIIIJIJGEHJJGEHIJJGHHHHHFFFFFFDDDDBBDDDDDDD@B@CCDCEDDD9>5?
@2UF
TGAAAATATGACTGTTGGAGAAGAAAGTAAGCAAGAACAGTTGATTTTGGATCACTTACCATCTGTAACAAAGGAATCATCACTTAGAGCAACTCAACCA
+
BCCFFFFFHHHHHJJIIIIIJJJJJJJHHIJJJJJJJJJJIIJJJJJJJJJJJJJIIIJJJJIIJHIIIIJIIIJHHHHHHFFFFFFEEEDEEDDDDDDD
@2UG
AAAGTTGATGTGATTGCCGGCTCCTCCAAGATGAAGGGCTTCTCGTCCTCAGAGTCGGAGAGCTCCAGTGAGTCCAGCTCCTCTGACAGCGAAGACTCCG
+
<@@DDDFDHGHGHIIIJJJAHGGHJIIJJJGIIJJJJJJJJJJIJJJIJJJIIHCGIJGH?DECEEDC@A>CCDDCDC@CDDDDD>CDDDD@BD>CCDDB
@2UH
GACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTG
+
?@@FFFFFHHGAHIIIIIIBE<EGHIGIIHHIIIIIIGGIIIGGGHGH7BA;FHG@GGEHEHHHFFFFFFEECCACCDDDBBBBBBBDDC@CDDDDDDDCB
@2UI
GACGAAGAAAAATAATAGCAGCAACAGCAATGTGAGCAAGAAGGAGCCAGCGCCCATGAAGAGCAAGCCCCCTCCCACGTATGAGTCGGAGGAAGAGGAC
+
=;@:=ADDD;BDFE@CF?CBH@@@<CGE;BEB?CF?9?FGDD*09D;7?B@F<FF@.7?>>ADBDDB?B?CB:;?@5?855>@:>A:59-0988?B1?(2
@2UJ
GGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAAT
+
CCCFFFDDFHHDHEIIIIIIC@HHGIIGIIIIIIIGGDGGGGBG@GBHIGHIIIIIIGGGHIIGEHBEFFFEFEE>ACACCCD;?ADBDDA@@CDACCCD
@2UK
CATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCT
+
@<@DBB>DDHHDBBEHHBF?FHID;<F@AFGHIIGD9FGFDFEHBBDDGGIGAG:FGHIGEGGEH=.=EDE;;;;>>@@:A5>@A>CCC>>>AACCCCCBC
@2UL
GCCTTCCCTAGGTGACCGCTCCAAAATTTCCAAGGACGTTTATGAGAACTTCCGTCAGTGGCAGCGTTACAAAGCCTTGGCCCGGAGGCACCTATCCC
+
@@@DFDBEHFBD<A<FEHAE@EFHHIIIIIEHIIIIGH@FGEGIGHIIICGIIICHIICHFFFHFFCCCCCCCCCBCCCCCCB@BBBCCCCCCCCCCC
@2UM
GTCAATATTGATGACTTGATTAGAGACCAAGGATTTCGTGGTGATGGAGGATCAACCACAGGTTTGTCTGCTACCCCCCCTGCCTCATTACCTGGCTCACT
+
@?@DDDBB?4CFDCC<<??A<@IHCAD:CECDB*??FGCF>8?B9D3??F?FFIIB=;12@F@C>@@@;>AC;CBDD??=25<?BBB@AA@@:>?8<>@:>
@2UN
CTTCAGACATTAACCATGACAAATTCAGGCAGTACTCAGCAAGGTACAACTATTCTTCAGTATGCACAGACCTCTGATGGACAGCAGATACTTGTGCCC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJIJIJHHIIJJJIJIJIFHIJJIJIJJJIJJJJHIJJJJJJIJJJIIIJIGHHHHHFFFFEEEEDEDCDDDD
@2UO
CCTATCCTGGGATTCCTCCTGAGCGGCTCTTCAACCTTCTGAAGACCGGCCACCGGATGGAGAGGCCAGACAACTGCAGCGAGGAGATGTACCCCCTTATG
+
+1=:ADD?:=+<:2CG@FBGBF;??F?))090BF9?D9?*?<*BF@C0/'@'5A6,',,(-,5<5?<@?(,29@(3>A(()0)5-((+444:>(2<B(+(4
@2UP
CACCATCTCCATATCATTGAGACCAAATTTGAGATGATCAAACTTATAGATATTGCACGACAGACTGCACAGGGCATGGATTACTTACACGCCAAGTCAAT
+
CCCFFFFFHHHHGJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJGJJJJJJJIJJJJJJJJJJJJJJJJHHHHFFFFEECEEEDEDDD@BDDDDCDEDE
@2UQ
CGGGACCCTTGGGAGTGGAGAGGAGAGGGGCTGGGAAGGTTATAAACCAGGTATCTCTACATCAGGATGGCCATCTAGGAGGAGCTGGGCCTACTGGGCAC
+
;;99;/53:9;?@(2(28><<15(5.339(-7=(768<6.;>1=83.=(.;.<;;>=?13==?>8=3==<<3;(53==;:<5(8(25((++8(6656588-
@2UR
GTGAACTTTGTCCCTCCCCATCCATCCTCCATGCCTGTCACTTCCTCCAGCTTCTTTGGAGCCGCATCACAATACTGGACCTCCCCCACGGGGGGAATCT
+
@@@DD?DDHHFHAGBCFIIIFHEHFHIGGHGDGHGEF@DADHGHGCIIE<FF9BFGHGI:=F@/@@<=AE@DECEBCC>ACCCBBB==@=<@B@BBBA@>
@2US
CACCTATCACGACAAATCACCGGCCTTCTCCTGACCCCGAGCAGCGGCCCCTCCGGTCCCCCCTGGACAACATGATCCGCCGCCTCTCCCCGGCTGAG
+
@C@ADBDDFDDFFHGFGECHG<@>DGH@DHIC@FGGIEHGGAGEBBHFFDD@B?;=BDBBDDDBDB<?ABBACDDDCC?@@BBD@>CCCCDB9@@BAA
@2UT
TGCTCGAGAATGTCGCAGAAAGAAGAAAGAATATGTGAAATGCCTGGAAAACCGAGTTGCAGTCCTGGAAAATCAAAATAAAACTCTAATAGAAGAGTTA
+
@@@DDFFFHGHHHJJIIIGGGGGGHIGIIGGHIJIJJJIIJIIIGGIJJJJIGGHIJJIGHG?CCDEDEFEEEDEDD@CDDDDCDDCDDDDDCCACD@CD
@2UU
AGCCAGGGTCGGATTCCAGTTAAATGGATGGCAATTGAATCCCTTTTTGATCATATCTACACCACGCAAAGTGATGTATGGTCTTTTGGGGTCCTGCTGTG
+
;?;DDDDA+<CDDB1<BEFEFEEEDEIE>DD>;DDDDEAABDEDEAC9AB))84;A@CCADDEDDD<@D?>.;;>A5>3>?;55:;:A?';0)+4:>A>>A
@2UV
CGAGAGGGAGACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTAC
+
@@<DDDDDHA<FFGGIIIGGDF@DGGD@F?DDHA<FC;F@EAEEHEHDBBD<A@BDBDBDDDCCCCC:@CCCC4>:@C<?CD9A3:9@>>BBAA<?ABC
@2UW
CATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCT
+
CCCFFFFFHHHHHIJJJJIJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJIJJIIJIJJHHCHHFFFFFFEEEEEEDDDDDDDDDDDDDDDDDDDD
@2UX
CTCTGAGAAACAGCACTCATAGTAGCACAGCTGCAGACTTACTACAAGCCAAACAACAGATCCTCACTCATCAACAGCAGCTTGAAGAACAAGACCACTT
+
CCCFFFFFHHHHHJJJIJGHJJEHHGJIJJFGICFIIJJFIGIJJJJJJHJJJJIJCGHIJIIJJJJJJJJHHHDHDBFFFEDEEEDCD?CDDDCCD?CD
@2UY
CGTAGACACACGAGCATATTTCACCTCCGCTACCATAATCATCGCTATCCCCACCGGCGTCAAAGTATTTAGCTGACTCGCCACACTCCACGGAAGCAAT
+
1::BD7BDHHFHAGGHEAEEIEGGIIIHIGGIGIJ4DF>DF@FE<CB<CGFHEHGBE/=3,28>>(5;;>B;,5>((+:?7<?>8<?C<@325<85<9A@
@2UZ
CGGCAATTCACTAACAAGAAAACAGGGAATTTTTGGGAAATATGAAAAGCCAAAATTTGTGCAGTGTTTAGCATTCTTGGGGAATGGAGATGTTCTTACTG
+
@?<DFFFFFHHHHIIIIIIIIGEHGIIIIIIIEIDGIBHIIDIIFIIIIIIBHIIIIACHIGHGCEHHEHHGFFF@CE@CDDB?B>ACDDDDDDDDACCCD
@2V0
CTCCAGGACCTCAGCGAGAAAGGAAGTCATCTTCATCCTCAGAAGACAGGAATCGAATGAAAACACTTGGTAGACGGGACTCGAGTGATGATTGGGAGATT
+
@@@DFFFFGGHDFHIHBFHGEDGHGGGFGIGGGGIGIAHAEGCD@CHHGIGIJGIJJJGGGGG@AC=CED@D@;BACDD@BDD<@59AC@3>@ABDBD<CC
@2V1
CTTGCCAGGACCTTTGAGGGCCAACAGCCCACCCTTGAGGTCCAAAGAAAATCAAGAACAGAGCTGTGAAACCGTAGGGCATCCCAGTGATCTGTGGGC
+
@@@DFDDADFFDHGABEEBG>F?GHGGGIIIGIIIIGBDGH@FHHHEII>GIEHGGIIGGEEHEHFCECCDECCCB==BCBCACBCC@@CDAC@>@C@B
@2V2
CTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACC
+
CCCDFFFFHHGHHFIJJJIIHGIJIHHIIIIJJIJJJGIIIIIJJIIJIDGGJJJJJIGHHHFFFF>ACEEEDC>BDDDDDDDDD@<ACDDDCDDEDDDDD
@2V3
GAAATCTCGATGGAGTGGGTCCCATCAGTTTGAACAGTTGTCTGGATCCATTTTGTGGATGGCACCAGAAGTCATCAGAATGCAAGATAAAAATCCATAC
+
@@@FFFDDHFHHHGIEFEGHIJJJJGJEIIIGGIIGJJJJFDGGIIGHGIIJJGI;FFGCAEG>AGCCCHH=AEHHFFDFEF@CECDCCDDDCDDCCCC<
@2V4
CTGCAAATAAAAGCAGTAAAGTTTTCTGAAATCAGTCTTTCCTGTGATCTTGAAATAAAAGTATAAACCCTTATGGTTTTCTTATGGTTGGTACGGTTGTC
+
C@@DFDDDHHFHDHGGEGIGGCHHGHGGIIGIGGIH<EEHDFHHIGEBFGGEGHGDBDHGHGHIHIIEHCHHF7CFFCHIIIGFDHEHEDDC;>ADABB;A
@2V5
CAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATG
+
@@@ABDDFBBFDHECFEGGIII@HIGGEEGHGGJIIIDHG@?BDH@9D*BFHGGIACF;=FGGHGH;=AEDFD>?CCDECEE;>>AC2<A6=?@@CCDDEC
@2V6
TGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGG
+
CCCFFFFFHHHHHJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJIJJJGHIIJJHHHHFFFDDEDEDDDDDDDDDDDCDDDDDDDEDDDDEDDEDDDDDDD
@2V7
CAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCT
+
B@@FFFFFHHHHHJIJJJJJJGGIJJHIJJJJJIGIIJJJJIJJJJJJJIJJJJJJJIJHHHFFFFFFEEEDDDDDDDDDDDEDDDCDDDDDDDCCDDDD
@2V8
CAAGCCCACCAGCTTGTGGAACCCAACGTACGGCTCCTGGTTTACAGAGAAACCCACCAAAAAGAATAATCCTATAGCAAAGAAGGAGCCACACGACAGGG
+
CCCFFFFFHHHGHJJJJJJJJJJJJJJJHJJIJIJJJIJJFHIIJJJJJJJJIJJHHHFFFFDDDDDDDEDDDDDDEDDDDDDDDDDDDDDDDDDDDDBDD
@2V9
CTCCCCCACGGGGGGAATCTACCCCAACCCCAACGTCCCCCGCCATCCTAACACCCACGTGCCTTCACACTTAGGCAGCGACTACTAGAAGCTTACTCATC
+
@@@?;DDDF@FDF:7@:B<8CCC@B@B<79B88?B82<)80)6&0<>@>CCBC3?9?@B22??CC:4>@C9AA:>C3?B&9@<B9>>C:>ACC>ACCC::@
@2VA
CAAGAAGGAGAATATATTAAAATGTTTATGCGCGGTCGGCCAATTACCATGTTCATTCCTTCCGATGTTGACAACTATGATGACATCAGAACGGAACTGCC
+
@@@FDDDBFBFFHHIJIIIJIIJIHIHGIGIEHGIFHHGHIIIIEIJIJIIJJIGHHHHHHFFFBACBCCDDDDDDDCCCDDDCCDDCCCDDDBBDDDDDD
@2VB
CCAAAAGCCATGAAGAGATTAATGGCAGAGTGCCTCAAAAAGAAAAGAGATGAGAGACCACTCTTTCCCCAAATTCTCGCCTCTATTGAGCTGCTGGCCCG
+
CCCFFFFFHHHHFHIIJIIIJJJJJJJJIJIJJJJJIIJJJJGIIJJJJJIJJIIIJIJJJIJIJJIJGHGHFFFFFFDCDDDDCDEDCCDDDDDCDCDDB
@2VC
GGAGAAATGGAGAATGCTTTAAGGTCATATTCAAATATTACAGTTAATGAAGATCAGATAAAGTTAATGAATGTGGCAATAAATGAACTGAATATAAAATT
+
@;@DDFFDHBHH?FHHIIIIEBAFAC@EF@E@9AEB*@E?CGF:C9C@GGI@GD<D?B?DBFGDFA@CBCD<@@;@AFAGIH;>CEC>EEECBEDFF>;@C
@2VD
CTGGAAAATCAAAATAAAACTCTAATAGAAGAGTTAAAAACTTTGAAGGATCTTTATTCCAATAAAAGTGTTTGATTCCTAAGAAAGAAAATATTTTTGTG
+
CCCFFFFFHHHGHJJJJJJJJIJJJJJJJJJGGHIJJJJJJJJJJIJJFIIJIJJJJJJJJJIJJJIJ=FFFGIGIJJIJJHHHHHFFFFFEEFEEEEDAC
@2VE
GTCACCTATCACGACAAATCACCGGCCTTCTCCTGACCCCGAGCAGCGGCCCCTCCGGTCCCCCCTGGACAACATGATCCGCCGCCTCTCCCCGGCTG
+
@@@ADFFFGHHFFEHHGFEGHJJGGIIGIHHJIGHIJJIIJIEIIGHHHFDDDBDDBBDBBBDDDDDBBDDDDDDDDDDDBDD<BDBDCCDDDDDDBD
@2VF
CAGAGGAAAAAGCAACAATGAGGTGGGTAGGGCCGAGGAGGGAGAGAAGGTGAAGGGAAAAAGAAGCAATGATAAGCGAAGACGGGAGGCGCAGCCACAGC
+
0;(:((((:)2-(.=2:6)23)))2((()15()-3;8?65''-''-(.)((.(6.('((,,('((,((((+3(((+(&+0&&(&)&&&&(&))055(87;3
@2VG
CTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCC
+
@C@BDBEDHGFHFGIIHGIHGIEGEHIIEEHGHGHCDHDHHEGIGE=BFBGHGCDFEHGGIFEEEAB@EB:>@@@CBB;A=A9ABDCA?CD>>ACCACBDD
@2VH
GAAAAATTCGATGGAGACATCAAACAAGAGCCAGGAATGTATCGGGAAGGACCCACATACCAACGGCGAGGATCACTTCAGCTCTGGCAGTTTTTGGGAGC
+
@@@DBDDDDF?,<@C@FGE?FDHFF>FC91?DGGDGF>D<B?06)?6@B=FFI;@C5=@A?==?B<?;8;9@?9<?AA>(:3((4>4:<?9@:><B@&2<5
@2VI
CCAGATAGCAGCTACCCCATGGACCACAGATTTCGCCGCCAGCTTTCTGAACCCTGTAACTCCTTTCCTCCTTTGCCGACGATGCCAAGGGAAGGACGTCC
+
CCCFFFFFHGHHGJJJJJJIJJIJJIJJJJJIJIJIJJJJJJJJJJJJJJJJJJJHHHHHHHFFFFFFEEEEEEDDDDDDDDDDDDDDDDDDDDDDDDDDD
@2VJ
CTGGGCCGCGTGGTGCACATCATCCAGTCACGGGAGCCCTCCCTGAAGAATTCCAACCCCGACGAGATTGAAATCGACTTTGAGACCCTGAAGCCGTCCAC
+
@@1ADDDDHD?DA?FFFIIEIEGGG@??DBDHI:6AGHICDCHHFHFEECBCD@>>CABB>;=@7;8<CC@@CCC@@B@@AC@<?CBBCC?CCCBBB>9@C
@2VK
GAAATCACTGTGCTAAAGGCGGCTTTGGCTGATGTTTTGAGGCGTCTTGCAATCTCTGAAGATCATGTGGCCTCAGTGAAAAAATCAGTCTCAAGTAAAGG
+
<?@DDDDFHDHFFHIGDGECGG>HGIEHGGHJCHBFHHBBFEGGEHHHFEFFE?CCEEECCCCCDDDEDC@BCBC?:@5;>C?3?:+:>CC>ACC@@ACAC
@2VL
ACAAGAACAGATTGTGCAAAAGAACCAAGAAATAAAAAACATGAAATTAGAGCTGACTAATTCTAAGCAAAAAGAAAGACAGTCTTCTGAAGAAATAAAAC
+
1:;D;DDD8??+2<+,:CEFEFDEEFID@??CC<CDB?DDDDDIC>DE@?=4BD@3==@C@@:A;7A9??A=@D?@AAAAA?5>AD>>>A>A>>=:AAAA:
@2VM
CACTCACGAGAGCTGATGGCACTAACACTGGGTTTCCAAGATATCCAAATGATAGTGTATATGCTAACTGGATGCTTTCACCCTCAGCGGCAAAATTAATG
+
@<?B?AD?FHA?FBB9EA93C>D>CGHIIIIG?C@D<?BG29?FGG@BBBB9CBF<B=FA@F@F>@77@D==?CCEEB>C>DE?B;A@?;2;B<CC@:@>@
@2VN
CAGCAATGTGAGCAAGAAGGAGCCAGCGCCCATGAAGAGCAAGCCCCCTCCCACGTATGAGTCGGAGGAAGAGGACAAGTGCAAGCCTATGTCCTATGAGG
+
@@CFFFFFHFGHHJJJIJJJJJJJJJIJJIGGFHIFIIIJIGGIJJIJJJJIGIGHEFD?C@EAC>BD?BDBDDDDDDDDDDCDDDDDDDDDDEDCDCCDD
@2VO
CTGGTGCCACCATGAAATTGTCCTGGTGATCTGTGGAATTTAATGACCCAGTGCTGGGCTCAAGAACCCGACCAAAGACCTACTTTTCATAGAATTCAGG
+
;(552;4)...:)2.98.48@8:??)28>9.==1=63?1...)=6=>;>(.0)0.71((<(==.)8;7=5'5',.(..69;-(-44(,(,,(,(:52(33
@2VP
GATGCAAATACCATAATTACATGCGGTAAATCTCATATTTTCTTCTGGACCTGGAGCGGCAATTCACTAACAAGAAAACAGGGAATTTTTGGGAAATATG
+
@@@DBDDD?DCFHGDGFBH@?<EAGE<@FHGBGFBHGABDHIIHHDBA>GGBB?B@BAGG8=EE?D@BEEBCCC@CCCA?AAB@?BCCCC@BB?CBCCC>
@2VQ
AATGAGGGTTACCTATGGGGCTGAAGGACTGCAGCAGTTACAAGAATTTGAAGCTGCCATTAAACAAAGAGATGGCATTATAACCCAGCTCACTGCTAATT
+
@@@DBDAACD?DBAGGGEG+8?@EGE>@E@;F?;DHBDFHE?DF9DGCHG<B>A8CFHHHEH>@@@DGEHCE;@C@@CCC>AD@A?BB@ACCCCCCCCCCE
@2VR
GCAGGCGCTGGGGCGAGCGGAAAAGCAAGCCCAACATGAATTACGACAAGCTGAGCCGGGCCCTCCCTTATTACTATGATAAAAACATTATGACCAAAGTG
+
+++:?1AA@@1:<??:DDDD<A<DE<).)==2(;=;>>;;>>>A?18;?(2(+><(3:-;<?7<??((4:>ABAAA>4>::AA::-(+4:A:(:>(+<<34
@2VS
GACAAGTGCAAGCCTATGTCCTATGAGGAGAAGCGGCAGCTCAGCTTGGACATCAACAAGCTCCCCGGCGAGAAGCTGGGCCGCGTGGTGCACATCATCC
+
?<?DDBDDH<?DFBF@EHE@BEHGE>BFHG<EHGDGHFEAEEHHCFGIGFEHC@DGDEHGFEHCD<>BDDB5>;<CCACDA?B7<9>>??@CDAACCCCC
@2VT
TTTTTCACCATTCTTCCACCCTGGAAACTCTATACACACACAGCCGGAGGTCATACTGCATCAGAACCATGAAGAAGATAACTGCGTCCAGAGGACCCCC
+
?<<ABB:DDA<DDAEE@4<AEDDAE3EEBE*?9:CC:D8?@7)8B)(.-;5@CC))=4=?A>>?AA@((.;.;3((-;-;;>:>(',3,++4+(882<?.
@2VU
ATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGT
+
CCCFFFFFHHHHHJJJJJJIJJJJIJJJIJIJJIIJJJJJJIIIIJJJJJJJIJHHHHHFFFFDDDDDDDDCDDDDDDEDDDDDDDDDDDDDDDDDDDDD5
@2VV
CCTACCATGCCCACCAGCAGAAGGTGAACTTTGTCCCTCCCCATCCATCCTCCATGCCTGTCACTTCCTCCAGCTTCTTTGGAGCCGCATCACAATACTGG
+
===4A:;ADAABFGIGIGFGCFG;AB49C@ECE<D@G>?DHG;)9?FBCB?B;=@CEDHFGG>@;@CD7AAA.=;;@DC>;>;>@;;8?8;C:5@>A>3:@
@2VW
CAAATTCTCATTTTATTGCCTGGACTGGTCGAGGCATGGAATTTAAACTGATTGAGCCTGAAGAGGTGGCCCGACGTTGGGGCATTCAGAAAAACAGGCC
+
@@<DDDB?D?FDFAEBF<@HHGG:<CEEEHHEGHII@GGGBGGG@B9FG>FFBB:FCGCEAA>;.67=?>DB9=@BBBBBBBB9AACD>@CACBB??B@@
@2VX
GTAAGCAAGAACAGTTGATTTTGGATCACTTACCATCTGTAACAAAGGAATCATCACTTAGAGCAACTCAACCAAGTGAAAATGATAAACTTCAGAAAGA
+
@@@DFFDEFH?DHIGGIGEIIJGIHFGHIJJIJJJEHIGHGIIIGIJIJJIJIJJIIJIIHJIJIJJGIJJCDCEHACHFFFFCB>CEEEEDCDDDDDC>
@2VY
CTTCATCCTCAGAAGACAGGAATCGAATGAAAACACTTGGTAGACGGGACTCGAGTGATGATTGGGAGATTCCTGATGGGCAGATTACAGTGGGACAA
+
CCCFFFFFHHHHHJJJJJJJJJJJJIJJJJJJJJJJJJJJFHIGIIJJHIIJJJJGHIJJIJIIHHHHDFFFFEEDEEEDDDDDDDDDDD@CDDDDDD
@2VZ
CTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCCCAGACCACTGC
+
?8:+==2BF<<:DDG<CGGDC?<@<<C?:E3*CC;D??F?GI300/09*/9.B;88C7)).;;;5(5A7B7);B3(;A:;A3---;55(5899<9(2+:4
@2W0
TGGCAAAGCTCTCCTGCTGCTGACCAAAGAGGACTTTCGCTATCGATCTCCTCATTCAGGTGATGTGCTCTATGAACTCCTTCAGCATATTCTGAAGC
+
1++=?BDDFDFAFFBGEFIIIIIEC3CCGEIF@FGFAFF:DEFFIDEBCFFEE>EEDFFACEEEEFDFFACCE:>BBDDDACBCBCBBBBAB@;;ABA
@2W1
TGGCAGAGTGCCTCAAAAAGAAAAGAGATGAGAGACCACTCTTTCCCCAAATTCTCGCCTCTATTGAGCTGCTGGCCCGCTCATTGCCAAAAATTCACCGC
+
;;;=A+=BA?A:A:AA<CFF;CG@BGC3?EGFAFBFAGIBDGFD<@FDFFFFFB=C5F@E@=DEC;==C;3?;7;?;?:823;@AA:5>ABBB?A4:>@<9
@2W2
AGAAGGAGCCAGCGCCCATGAAGAGCAAGCCCCCTCCCACGTATGAGTCGGAGGAAGAGGACAAGTGCAAGCCTATGTCCTATGAGGAGAAGCGGCAGCTC
+
CCCFFFFFHHHHGIJJJJJJJJJJJJJJJIJJIJJJJJJJJHJJJGHHGHHADFCEECDDDDDDDCDDDDDDDDDDDEEEDDDCCCDDBDDDDDDDDDDCD
@2W3
AAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTAC
+
@@@FFFFFHHGFFIIGDH@GHCHGIIIIIGGCH@EIDBDFGHIIIIGIFIGIIIIIIIFFABDDDCDDD?ABBDBDDCCDDD@CCDCCCDDDCDDDCC@C
@2W4
AACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCC
+
?<8BBB??DD;?BFIG?:FHHHFEGFBFG1CF>FCFFF@FEFIC@GEFE/9DFFEFF25@@CECFEFEEFFDDDDCC>>@AA;@;AA@??BA?>AB@@38?
@2W5
GCCCCCTCCCACGTATGAGTCGGAGGAAGAGGACAAGTGCAAGCCTATGTCCTATGAGGAGAAGCGGCAGCTCAGCTTGGACATCAACAAGCTCCCCGGCG
+
@@@FFFFFHHHFHFHBGGGHHIGIBBDHICG?@FDFHBBFDGIGIGHJJIJDEIGHHEHGBDDECCDBDBDCD:>@C@A@:>CACCDDDDDB>>CBDDDDD
@2W6
CACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCC
+
CCCFFFFFHHHHHJJJJIJGHGIIJIIJJJJJJJJIIJIIJJJIIGGIHJJGHIIIHGIJGIIIGIJJHHEHHGFDFFFEEEEEDDDDDDBDDDDDDDDD
@2W7
CTATGATAAACTTAGCCGTTCACTCCGCTATTACTATGAGAAAGGAATTATGCAAAAGGTGGCTGGAGAGAGATATGTCTACAAGTTTGTGTGTGATCC
+
?<@=1DB?DFFBF>4CEFAFFG>CHBE>CHG>@D<??FHG<G@D??D?BAGFACF>CB77@FB>;E?;)(5;(;6@;>B;@>;;35;;;((,9(9:@:5
@2W8
GTTACCAACACTAAACTGGATCCTACAGCCAAACTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGCGTTCATTCCGACAGGACCACCCC
+
9<3@?46@8(=)@@4.@6)3)3288@1))(.:).=1)=?).<.)0..>)>9>7=6>))<6>?1.();.5-','9=(6(,;3,(,,,:('))&+(((((20)
@2W9
GCCTGGTTGGAGCGAATCTGCTAGTGAAGATTGGGGACTTCGGCATGTTCAGGGATGTCTACAGCACGGATTATTACAGGGTGGGAGGACACACCATGCTC
+
8????DDDBD:DDE1<:82A@B9*1?*??DA<DB;@D@D8B1.;A@2.)8)=)6;);A)7))..).(,9'39>A;>33,9=5<9>>?9((+89588+:((4
@2WA
CGTCCACACTGCGTGAGCTGGAGCGCTATGTCACCTCCTGTTTGCGGAAGAAAAGGAAACCTCAAGCTGAGAAAGTTGATGTGATTGCCGGCTCCTCCA
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJIIJJJIJJIJIJJIJJJGIJJHHHHHFFFFEEEEEEDDDDDDDDDDDDDDDCCDEECDDDDDBDDDDDD
@2WB
CAGCTCGGCTAGGTGACAGACGCAGGGGATTTTAGATCGAGAGCGAAGAAGAGCGGAGGTGGAGAACAGGAGGTGGGGTCCGGGGGTAAGGACACTGTGTG
+
-(0;(.-(2((:(2).))3)(:(((18(0(<<=)).))((((-6'''53)))(.,'''',7(((+(+(+(62&+(+&&)&(&&)0&&)/6(+2(+((((((
@2WC
GTACAAGTACCCTTCTGACATCTCCTACATGCCTTCCTACCATGCCCACCAGCAGAAGGTGAACTTTGTCCCTCCCCATCCATCCTCCATGCCTGTCACTT
+
<B@FFFFEHHHHHJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJIJJJJJJJGHIJJJIJJHIJJIHHHHFFFFEEEEDEDCCDCDDDDDDDDD
@2WD
CTGCCCTCTAAGGCTGTTGGTGTCAGCCAGGAGGGTCCTCCAGGCCTTCCGCCTCAGCCTCCACCACCAGTTGCTAAACTGGTCCCCATTGTGCCCCTGG
+
?;:D?:+22CDD3EE@<:3C+322AF<F8::D1)))000**09BB?8B83A4(-577;7.?;;;(.=5.=>5>(-(5;,5(5,55<(,((((++(92(++
@2WE
CCTGGACAACATGATCCGCCGCCTCTCCCCGGCTGAGAGAGCTCAGGGACCCAGGCCGCACCAGGAGAACAACCACCAGGAGTCCTACCCTCTGTCAGTGT
+
??;::B2A?:2A:C:<E:F:CEE?DEDDEI?((77==.81@D@D@;3=C5??6((;,3/8'39<<88(+:3+<88><<<8((99++>A<<:<3(:A>4>>:
@2WF
CCGACGTTGGGGCATTCAGAAAAACAGGCCAGCTATGAACTATGATAAACTTAGCCGTTCACTCCGCTATTACTATGAGAAAGGAATTATGCAAAAGGTGG
+
CCCFFFDDHHHHHIJJIJJJJJIJJJJJJJJJJJJJJJIJJJJJJJJJJIJJJIJJJIHHHHFFFFDDDDDECDEFDDDCDDDDDDDCDDDDEDDDDB4@B
@2WG
GCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTAT
+
CCCFFFFDDHGHHHHJIIJIIIGIGIJJJIGIJIJJJJIGHIIGIJIIJJIJGIJJIJJJJJIJIJJIHHHHFFEFFFFEEEEEDDDDDDDDDDDDDDDDD
@2WH
GGAAAGACAGAAAAATAATTCTGTGGGATCATGATCTGAATCCTGAAAGAGAAATAGAGGTTCCTGATCAGTATGGCACAATCAGAGCTGTAGCAGAAGG
+
@@@D?DDBDFDHHIIIIIIIIIIFFGBHHHDGIG@:DGHIGIIIIEGHIHIGFEHIEIIIIII@FEC=FHADHI@EHEEHFFFFFCACCE3>@>>>=AC?
@2WI
ATGACATCTCCTGTGACTCTCACCTCTCAGACAACTAAGACAGATGACCCCCAATTGAAAAGAGAAATAAGGTTAATGAAAAACAGAGAAGCTGCTCG
+
CCCFFFFFHHHHGJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJIIIJJJHHHHEHFFFFFFFEEDDDDDDDDDDDDDDD
@2WJ
GAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACT
+
@@CFFFFFHHHHHJJIJJJJJJJJJJJJJJJJJJJJJJJJIJIJJIJJJJJJJJJJJHHGIJHHHHEEFFFFFEACEEDDDDDDDDDDDDDDDDDDDDDD
@2WK
GCCAAAATTTGTGCAGTGTTTAGCATTCTTGGGGAATGGAGATGTTCTTACTGGAGACTCAGGTGGAGTCATGCTTATATGGAGCAAAACTACTGTAGAGC
+
@@CFFFFFHHHHHFEGEFJJJJJJJIJHGIIJJJFGIIIJIJJIJJJJJJJJJJGEHIJIJJIFFEDH@EGIHHHHDHFFEFCDCDEEE?CDDDDCDDEDD
@2WL
TATCGGGAAGGACCCACATACCAACGGCGAGGATCACTTCAGCTCTGGCAGTTTTTGGTAGCTCTTCTGGATGACCCTTCAAATTCTCATTTTATTGCCTG
+
<@@FDDDDHDHHHJJJJJJJJJJGIJEGHGIIJHAHGDHEHFFHFFFFFCDCEEEDDD9@@@CDDDDDDDCCCCCCDCDDDDDDDDEDDEDEEEDDDDDDD
@2WM
GAGCAGTATTTGGTTTGAACTTTGATTCTCGGACGTGTTAAGAAAACTGGGAGAAAATGGAGTTTCATGTGGTTTCTAGATGGGGGACCTCTTAATCCAT
+
-(0=(.<.2;)2)<=79;=3<>)))992).((((1(()0))))0).38))<(-'(..8)))...6.))))..6(((((((.((,('',((+((5(+(++(
@2WN
CACAGCTTCTATTTAGTCACGAAGAAGAGCTTTCCAAACTGAAGGAAGATTTAGAAATTGAACATCGAATAAATATTGAAAAACTTAAAGATAATTTAGGC
+
CCCFFFFFHHHHFIIJHIJJJJJJJIJJJJJJJJJJJJIIJIJJIIJJJJJJJJJJJJJGIJIJJJJJJJJHHHGHHHFFFFFDEEEEEDDDDDDEEDDDC
@2WO
GGGATGAGCACTTTTTGTGTGCATATGATCTGCTCGAGGAGGAAACGTACTGGCAGAAAGCTGCCTAGGATGTGGATTGAGAGGGTGGATAAGTAATAAA
+
8<189())2=34))))(()3()3)).2@1.):3)1(1-(:(<=?7)(0((./.6.((.;0))))..8.=;=963((.(97-((,35('(((+22((8=(3
@2WP
CTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTT
+
:==++2+@A<=3+27<?37A@37+?A4AC+?4@*1*:?;A5?**00)0=2A?AAAA:</5>2A<)7)7>;);39/;3;;,9;9=6'88+388;7:2839;2
@2WQ
CCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGT
+
CCCFFFFFHHHHHJJJJJJJGHIJIJJJJIJJJJJJJJJJJIIJIJJJJJJJHFHHHHFFFFFFEEEEEDDDD@CDDDDDDDDDDDDDDDDDDDDDDDDDD
@2WR
GAAGAAATAAAACAGTTAATGGGGACAGTCGAAGAACTTCAGAAGAGAAATCATAAAGACAGCCAGTTCGAAACTGATATAGTACAACGAATGGAACA
+
CCCFFFFFHHHHHJIHHIIJJJJJIJJJJJJJJJJJJJJJJJIJJJIJJJIIJIJJJIJJJJIIJIHHHHHHFFFEEEEEECBDDDDDDDDDDDDDDD
@2WS
GGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTT
+
?@@D1D>DFF<DFG>FF<:<<CF:4+CBHFF4:*C?CB)1B@FGEGBG?D<@0'6@4@AADFC>C>?B>3@9<?B=@??9<?B;B@BBA3:4:?@A9@B@
@2WT
TCCAACTACAGTGAAAATGAAAAGTTCTGTCTTTGATGAAGACAAAACTTTTGTAGCAGAAACATTGGAAATGGGTGAGGTTGTTGAAAAGGATACAAC
+
@@@D;BDDHHHDH>FBDGHIC?CBHHGHGGHEHGG9EGIEBBGHGHDHHIIIGFHHIIIGG?==FGGGCG;@FGH7ACCH=BC?=>CACCCB@A>>ACA
@2WU
CCAGTCATGAGCAGGGCTTCTCTGTGGAACTGGAAAGTGAAATTTCAACCACAGCAGATGACTGCAGTTCAGAGGTAAATGGTTGCAGTTTTGTGATG
+
@@@B=BDD=CDDFFDGFIDBDB@H??F<CC@?B9G@G1:??FDF@DF<BBGFCF8B=8=F>CCFFEEEFA@@=AE3=BD;BD7>=ABC;@A@@;=>>A
@2WV
AAGAGATTGAAGTCTCTAAAGATCACCTAAAACGAATCCTTGCTCTAGCAGCAGCAGCAGAACATAAATTAAAAACAATGTATAAGTCCCAGTTATTGAC
+
(;3-(@.@42)..2@)2>.>?8@1.)22@.6@)(-((:6:9.=?87.>=?8???1=3(93.=).=)<)3366)).-.9)6=8(:63==3356;=(-(,,(
@2WW
GTGAAAATGATAAACTTCAGAAAGAACTCAATGTACTTAAATCAGAACAGGACTTGATTAGAGACCAAGGATTTCGTGGTGATGGAGGATCAACCACAG
+
?@@?ADBD?HBHDE<FG@HBH@GD;?FD?ACE@:CB@?G?B<9CGH@0B?GHI@BB*0/BF<48=CHCCHHI>@;@C7A;1.7.7(.,=C;2>555?99
@2WX
CCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJIJJJJHGHJJJJJJGHIIJJJJGJJJJJJJJJIHHHFFFFFEEDDDDDDDDEEDDDDDDDDDDDDDDDDDDD
@2WY
GTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGC
+
CCCFFFFDHDHHHIJGIIJJJJIIIGIJIGIIJJJIIDFIIJJJJJJGHIJJFHHFFFFEEEEDEDDDCCDCC?CBDCDDDDDDBDDDCDCDDCDDDBDDD
@2WZ
ACTCGATCCGCCTGCCTGCGCACCTGCGCTTGCAGCCAATTTACTGGAGCAGGGATGACGTAGCCCAGTGGCTCAAGTGGGCTGAAAATGAGTTTTCTTT
+
@;;;==AB?F7?0A:EFB:@F@8:DEAG>@@?8?89BF==CF@FC@FF@36=AB1;?BDC5;>(5>??A@3<<::@:(5>8@9<8AB3+434(4>:>AA>
@2X0
GGGTGGTCTGTGCATATCCTTGAGTGGGCTGGGCGGTGTAAGCACTGTAGCCCTGCTGCGCTGCAGCTTGGCTATAGGTACTGTAATCCGTGGACGCCATT
+
B@@ADDDDFHDHHJJJJJIJJIFGHHJIIJJJJIJI;FHIJJIJJJFGHHHHHHFDDFEDB?B@DDDCCDDDDDCCDD4>@CCCDEEECD8?BDD@@B@DD
@2X1
GGCTTCTCTGTGGAACTGGAAAGTGAAATTTCAACCACAGCAGATGACTGCAGTTCAGAGGTAAATGGTTGCAGTTTTGTGATGAGAACAGGAAAGCCTAC
+
???DA;DDB+,<DCEEI@@>E@?FE>EEC@BE?C>ECD;;CBDAD>D<BABB@?B<9?<B@)9=;AC@.=CCCCACCC?.;)77);.;66@??>A?A?AA?
@2X2
CCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGC
+
@C@ADDFFHDBHHAFHIIIIEEDHGGIGIEHGE@FHIIIIEHIIIGGGHC@HDEIHHHGGIIIDFHHHFHFFDFFDDDDDDDDCCCC:CDCCDCACDDDBD
@2X3
ACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCT
+
@@@FABDDFHFBFHBCHIGFEGIGGGGE?EHC?EGGGA@GBCGEHC@GFGGGHCBG=;AHCEGIIGHH=CHFF>@@CEEEA@CCACDDCCDDDDCDD>BBA
@2X4
CAGGAAAAGGAGACAATCATTGAAGAATTAAACACAAAAATAATAGAAGAAGAAAAGAAAACTCTTGAGCTAAAGGATAAATTAACAACTGCTGATAAATT
+
@@@DDBDDHHHF;CEH>AFHIGIEH<BCHBHIEHGII>BGBDD??BF??@FE?FBGH;FH@GICDE>EE;CHEAA@@>?CCCDCCCC@;>>@C>>@>>A;>
@2X5
TTTCAAAACCCAAATTACTACCAAAAGTTACCAAAACTGCAGACAAGCATAAAGATGTAATAATGGACCAAGAAGGAGCATTTTTTTTTTTGTTTATACG
+
(;;==@9>3(--(()).))34)<::<1))2.61)8;<1?)66;3=<((<)=><=1637/3.)..)))))..60))((.((((.(.9''))0&88<:((((
@2X6
GCTCCACAGGGAACTCCGGGACCCTTGGGTGTGGAGAGGAGAGGGTCTGGGAAGGTTATAAACCAGGTATCTCTACATCAGGATGGCCATCTAGGAGGCGC
+
?@8?;ADBHDBAFAHE<CEBFEH=FG@FAD<GGDHGGFC2BHGHE;EHE@CEED??ACCDEECCBBBA:A:@A;@C>ACCCC:>>@CCCCCCACC@CBB>>
@2X7
GTCATACCAGTGCTGTCTCAATTGCAGGAAAAGAAACTCTTTCATCTGCTGCTAAAAGTGGTACAGAAAAAAAGAAAGAAAAACCACAAGGACAGAGAGA
+
@@@DDDDDHH??:CAEA@BF>E:A?:BGHE;GGHGIGHGHBGCB>FDFB<?GHDHHHI/?D=FHIC=CDHGEED?D@;>A>?B;;@8(<9<?@CBCC9?8
@2X8
GCGGCAATTCACTAACAAGAAAACAGGGAATTTTTGGGAAATATGAAAAGCCAAAATTTGTGCAGTGTTTAGCATTCTTGGGGAATGGAGATGTTCTTACT
+
CCCFFFFFHHHHGJJGIJJJJIIGGHIIHIJDHJJJGJHIIIGIJJJJJIJGIJJIIIIJGHHCH?CADFDFFFFEEEDEEDD?BBDCD??CDDDEDDDDD
@2X9
CTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAAC
+
=:?=+==2CCFFDFE9CFFEH9F@9BHGI<?G>9??;C>GE@F<?D9:???4BB8?86BC9;@(8CDDECCECDBB@?>A3>;35=;6=/;@04><9(+9
@2XA
GTTTTCTTTAAGGCCAATTGACAGCAACACGTTTGAAATGAATGGCAAAGCTCTCCTGCTGCTGACCAAAGAGGACTTTCGCTATCGATCTCCTCATTC
+
@@@FFFFFHHHHHJJJJJJJJJJIIJJIIIIHIJJJJJIJIJIIIIJJJJIJIIJJJJJJJJIJJJJJJHHGHHBFFFFDDDDDDDDBDDDDDDDDDEE
@2XB
CTCGATGGAGTGGGTCCCATCAGTTTGAACAGTTGTCTGGATCCATTTTGTGGATGGCACCAGAAGTCATCAGAATGCAAGATAAAAATCCATAC
+
CCCFFFFFHHHHHJHIJJJJJJJHIJJIJJJJJJJJIJJJJJJJJJJJJHHIJIJJJJJJJJJJJJDHIJHHHGGGFCEFDFEEEEEEDDDDDDD
@2XC
CACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATG
+
@@@DDDDDFADDAEH@BBFHC:FCFGG@A@@GDEGB:DB?F8@2=FBE7@FHEEHGEG>E<8AC@@BBBBCC:@CACCCCCDCCCCBB?B?5?ABBBACA>
@2XD
AACAAATCAAAGCTCATGATGGCAGTGTGTTCACACTTTGTCAGATGAGAAATGGGATGTTATTAACTGGAG
+
CCCFFFFFHHHHHJJJJJJJJJJJJEHHHHIJIJJJJJJJIJJJJJJIIIJIJJJJJJJJJJJJJJJJIJJI
@2XE
CAGCCCTTTAAATTCAGCTATGGAGAAAAGTGCCTGTACAATGTCAGTGCCTATGATCAGAAGCCACAAGTGGGAATGAGGCCCTCCAACCCCCCCACACC
+
CC@FFFFFHHHHHJIIJJJIIJIJJJJJJIFGHGIIHGJIGIJHHIJJIJJJIJIIGIIIJJIJIJIIIJ@FIJJJHGFHHFFFFDDDEDDDDDDDDDDDB
@2XF
CAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCC
+
@?@A?DAEDHDFHIABGHGDHGI1C@FGHGEGFEGEHBGIIIIIG@DCEGI3AEHE)?BE@CDC>>@;@CACBC@B:C>C>@AB?BBACCA?BB<<CCC:?
@2XG
TTAATGGCAGAGTGCCTCAAAAAGAAAAGAGATGAGAGACCACTCTTTCCCCAAATTCTCGCCTCTATTGAGCTGCTGGCCCGCTCATTGCCAAAAATTC
+
CCCFFFFFHFHGCFHIJIIJJJJJIIGJIJJGHIJIIGGGHIIGIIGIHJJIJJJJJIIIIJJIGGHHHFFFFFEEEEEBDDBB:@BDECCDDDDDDBDC
@2XH
GGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATAC
+
CCCFFFFFHHHHHJJJIJJJJJJJJJJJJJJJIJJJJJJIJJJIJIJJJJGIJJJIJJIIHHHFFFFDEEEEEEDDDCDCDDCBDD9CBD?BDDDCDDDED
@2XI
CCCCAATTGAAAAGAGAAATAAGGTTAATGAAAAACAGAGAAGCTGCTCGAGAATGTCGCAGAAAGAAGAAAGAATATGTGAAATGCCTGGAAAACCGAGT
+
CCCFDFFFHHBFFHFGEEEHIJJJCHIIGIJIIIIIJJIHIIIGHGIIIIEHIGGGGCGDGGBHHCC@DDDECEEDCEDDADECCCDDDDDDDDCDBDBB?
@2XJ
ACTAATTCTAAGCAAAAAGAAAGACAGTCTTCTGAAGAAATAAAACAGTTAATGGGGACAGTCGAAGAACTTCAGAAGAGAAATCATAAAGACAGCCAGTT
+
CCCFFDFFHHGDDHJIJIGHHIIEHHIHIJJJJIGGIIHDEIIJIGIIJJIIIJIIJGHEHCCGGCEHHHHHACDBEDEDEEEC;ACDDCCDDDDDBBD>C
@2XK
CAGCTCCCAATGTGCATATAAACACAATAGAACCTGTCAATATTGATGACTTGATTAGAGACCAAGGATTTCGTGGTGATGGAGGATCAACCACAGGTTTG
+
B@@FADDFHGHHHIJJJJIJJJJJJJJJIJHFIIHJGGHGGHHJGHII<EHIJIJJJGFGIGGIIHIHGIJIDGIHCHEEFFFFD?ECBDDDDBDDDACDB
@2XL
GGACTGCAGCAGTTACAAGAATTTGAAGCTGCCATTAAACAAAGAGATGGCATTATAACCCAGCTCACTGCTAATTTACAACAAGCAAGAAGAGAAAAGG
+
;@;=BBD;C83CDF>FEG?CFE9B?CBAE9FGGAB4?CFGGGIH9?F9?FDAHG@D?FFH26CGFH;=D;@EH@EHF@EE@@BDE=>;>=;>;;;>ACCB
@2XM
TGAACTATGATAAACTTAGCCGTTCACTCCGCTATTACTATGAGAAAGGAATTATGCAAAAGGTGAGCAGCTAATACAGCATTAAAATTCATTGAAATGTT
+
CCCFFFFFHGHHHJJJJJJIJJJJJIJJJJJIJIJJJJJJJJIJIJJJJJJIJJJJJJJJJJJ=DHIJJHHHHHFFFFFFEEEEEEEEDCDDDDDDDDDEE
@2XN
CTACTTCTCTGCCACAAACTGTGGTGATGACATCTCCTGTGACTCTCACCTCTCAGACAACTAAGACAGATGACCCCCAATTGAAAAGAGAAATAAGGTT
+
CCCFFFFFHHHHHJJJJJIJJIIJFHIJJJJJJIJJJJIIJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJHHHFFFEEEEEEDDDDDDDDDDDDCC
@2XO
CCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGT
+
@CCFFFFFHHGHHJJJJJJJIIJJJJJJJJIJIJJJJJJIJJJJJJJJIJJJHHHHHHFFFFFFEEEEEDDDDDDDDDDDDADDDDDDDDDDDDDDDDBDD
@2XP
TGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGG
+
@@@FFDADHBFDFHIGIIIEGGIIHHEIIIGIIBGIGDHBHHGEFIGIGEEHGHHEH?BEFDDDDECDDACCCDDDCC@CA:ACDEDD<CDDCDDCCDCDD
@2XQ
CTCAATCAATCTGATTCTATAGAAGACCCTAACAGTCCAGCAGGAAGAAGGCATTTGCAGCTCCAGACTCAATTAGAACAGCTCCAAGAAGAAACATTC
+
@@@DDDF?DDFFHHIGHFGGGGHIJGEHIEGIIIJGGGIGEIIIDGDGEIJJJJIIJIGIJGGIICCAEIJGHEEFHFFCBDCFEEEDEDDADACDD@A
@2XR
CTTAAAGCACTTAATGAAGAGCTTCATTTGCAAAGAATAAATCCAACTACAGTGAAAATGAAAAGTTCTGTCTTTGATGAAGACAAAACTTTTGTAGC
+
?<;DDDD;?FDD?AF<:<?IFGD<FBFEHHIC<A1CHEH*1?D*100B?3DB9?9B?FBD9D=FE8=C@C@F>CH:7=@@@??EFE>D;?DCC;666>
@2XS
CACACCTGGGAAAGGACCTAAAGGTGTATATCAAATCAGCAAGCAAATCAAAGCTCATGATGGCAGTGTGTTCACACTTTGTCAGATGAGAAATGGGATGT
+
CCCFFDFFGHHGHJIGHIHIGHHI<FCG>GHGIJGIJJJJJI)?GHJGGIJIIHGEIIIIJIJIIFCE=CCHEHDEEFFFFCFEECCCECCDDCDDDDCDC
@2XT
CCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGC
+
@CCDFFFFHHHHHIJIJJJJJJIHIIJJJJJJJIIJJJJIHIJJJJIIHIJIJJIIHIJJJJJIGHHHHGFFFFEDDDDDDDDDDDCDDDDDDDDDDDDDB
@2XU
CCAAAATTTGTGCAGTGTTTAGCATTCTTGGGGAATGGAGATGTTCTTACTGGAGACTCAGGTGGAGCCATGCTTATATGGAGCAAAACTACTGTAGAGCC
+
?@@DD=BDDDFFFBBCB<EDC<FBHCAEAHAF:BG@FFF@;GFD?F*0BFDD8?;;DG:CFF@@?DE);=C=EC>=ABBAD@;;?CCCBAAA;>;>AA5@B
@2XV
CACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGAT
+
@@@DDDDDBDFHAEHBAEHI>?GFEFCHIIGGGIIIGFEHBHIIII<FEHIIHGBHFAC@EDE;EEEDEBACCCCBCB=CCAACCCCC<@BBB?BB@ACCC
@2XW
CACAGCAGTTACTCTCAGCAGAAGACCTATGGGCAACCGCACAGCTATGGGCAGCAGAGTAGCTATGGTCAAAAAAGCAAGTATGGGCAGCAGCCTCCCAC
+
==+2A=;A74,<4?<<+<A+<+<++==+<7A>>@)?=?)))8409*/)/)(()'-.67=))77)7);))7)7(((;3;(((,5;;(953;0929838898;
@2XX
AGAAAAACAGGCCAGCTATGAACTATGATAAACTTAGCCGTTCACTCCGCTATTACTATGAGAAAGGAATTATGCAAAAGGTGGCTGGAGAGAGATATGTC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJIJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJGJJJJJHHHHHFFFFFFEEED;ADBDDDADCDDDDDDEDEE
@2XY
GGAGAAGCGGCAGCTCAGCTTGGACATCAACAAGCTCCCCGGCGAGAAGCTGGGCCGCGTGGTGCACATCATCCAGTCACGGGAGCCCTCCCTGAAGAATT
+
;<8B;DD?:F8DFBAFFFIFFCG>D@DGGFFFE@GFIEEEEBBFDBC>;>@ABBBB@555778<AB:ABBBB@>ABBB=@9>B>BBBBB88<343@BBBBB
@2XZ
TATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCC
+
CCCFFFFFHHHHHJIIJIJJJJJJJJIJJJJJJIJIJIJIJJJJJJIJJJJIJJJJGIJJJJHHHHHHFFFFFFCEECEEDDCDDDDDDDDDDDDDDDDBD
@2Y0
GAAAAAGAGAATGATCTTCAAGAAAAATTTGCACAACTTGAAGCAGAGAATAGCATTCTTAAAGATGAAAAGAAAACCCTTGAAGACATGTTGAAAATAC
+
@B@DFFFDHFHDHHIHHHDHIIEJJJIJHIJJGIIJIIIJIJIJJJIGJJIJJJIIIGIJIJIIIIJJIGJJJJHGHHFFFFEEEEDDDDDEDDDDDCDD
@2Y1
TGCCTGGACTGGTCGAGGCATGGAATTTAAACTGATTGAGCCTGAAGAGGTGGCCCGACGTTGGGGCATTCAGAAAAACAGGCCAGCTATGAACTATGAT
+
@@@FFDFDFHHHDHIGGIGIGIJJGHJJJJJJIJIJJHJJGHIGIJIJIH=CAEHHHEEB9ABDDDDBCDDEDDDDDDBDDDDBAD?ACCDDCCDDDDDE
@2Y2
GTCACATCAACGAGGAGGACACAGTGCCTCTTTCTCACTTTGATGAGAGCATGGCCTACATGCCGGAAGGGGGCTGCTGCAACCCCCACCCCTACAACGA
+
8==BBDDD>FBFFB<ADF=CDEGHFBFGGIIGIGC>GAEHGGEGGICFCGHIDI@CAHIG:7@CEHEED?AB?=?;?::@CCCBBBBBBB<B@BBCCC32
@2Y3
CTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTAT
+
C@CDFFFFHHHGHJJIGEGIIHIJJIIIJJJGIJIG@HGIIFHJJJJJJJJH?ECEEDEDDDFCAEEDDDDDDDCDCDCCDCDDDBBBDBDDDDDDDDDDC
@2Y4
GGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJIJJJJIIJJJJHIIJJJJIJJJJIIJJGIJIIIIJIIIHHHHHFFFFFFEEDDDDDDDDDDDDEDDDDDDD
@2Y5
GGAAAAGAAAAAAGAAAAGCACAAAAGGAAAGAGGAAGTGGAAGAGAATAAAAAAAGCAAAGCCAAGGAACCTCCTCCTAAAAAGACGAAGAAAAATAAT
+
;<77D8?A?<A+<)2CD?FEE93B8:1:8;*:*0?)?D/?3**?.8=B;=ACA@A4'.?;A366>?((;:919<<=3(+>A>AA90+5;><>A??><AAA
@2Y6
CATATTCTGAAGCAGAGGAAACCTCGGATTCTTTTTTCACCATTCTTCCACCCTGGAAACTCTATACACACACAGCCGGAGGTCATACTGCATCAGAACC
+
CCCFFFFFHHHHHJJJJJIIJJJJJJIIJJJJJJJIJJJJJJJJIIIIJJHJJJJJJJGJJJJJGHHGGGFFFDEDDDBBBD?CCCDDDEDDDDDDDDDD
@2Y7
GGTGATTTAAGGCGGCAGGTTAAACTCTTAGAAGAGAAGAATACCATGTATATGCAGAATACTGTCAGTCTAGAGGAAGAGTTAAGAAAGGCCAACGCAGC
+
B@BDFFFFHHHHHJJJJJJJIJJJJJJJJJJIJJIJJJJJJJJJJJJJIGGGIJJJGHHHHHFFFFFFEEEDEEEDBDDBDDDDEDDDDABDDDDDDDDDD
@2Y8
CCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGT
+
@@@BDF?DHFHHHIIIIIGBGGGH>GIEGBHIIEIFGIGEGAHG@GI@EHGHE????EE@DDEB@>CCCCC?=@@CC;:AB??BBCCCBBCCCCCCCABCA
@2Y9
CATCAGAATGCAAGATAAAAATCCATACAGCTTTCAGTCAGATGTATATGCATTTGGAATTGTTCTGTATGAATTGATGACTGGACAGTTACCTTATTCA
+
CCCFFFFFHHHHHJJIJJIJJJJJJJJJJIJJJJIIJJJJIGIJIJJIIJJIJJJIIJJJIJHIJJIGIJJJJJIIJIJGIIJJHHFHHFFFFFFEEEEE
@2YA
TAGAGTTTAGTGCTTCAAGGGCCAGGCTGCCAGGCCATGTTGCAGCTGACCACCCACCTGAAGTGTACCGCCGGAAGCACCAGGAGCTGCAAGCCATGC
+
??@?DAD?D?CCF::ADGIIFGIIGHB3C??CEFCHIDHDG@GI<F3*9BBFFGHGIIE@HGI=>7=AC=BCB>@BBB>??@<<@BB?C>CC>@?9>CA
@2YB
CGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGG
+
C@BFFFFFHGHHHJJJJJJJJJGHJJJJJJJJJJJJJJJJJJJJIIGIIJIJIJJJJJJJIJJHHHHHFFFFDCCEEEDDDDCCCDDDDD?CDDDDDDDDD
@2YC
GGAAAGCAAAAGGAGCAGAAATAAAGACAACAAATGAAGTTGTTTTGGCTGTGGAGTTTCACCCAACAGATGCAAATACCATAATTACATGCGGTAAATCT
+
C@@FFFFFHHHGGIHGIGHHJIJIHHJJIJJJIEIJGGIHIIHHIJIIGHIHHIHH@FHIJGJIIIFGHEDEBEFECECCEDDDDFD>ACCCBD;BBDEDD
@2YD
CTCCATATCATTGAGACCAAATTTGTGATGATCAAACTTATAGATATTGCACGACAGACTGCACAGGGCATGGAGCACCAGAAGTCATCAGAATGCA
+
@@CFFFDDHFHFDBEGIGHHEEGGGABHIHCHCGGCGIGHIIIEHIIJICGGIIIJIIGHHGGHIIGGHG>EHFFFFFDCDEDD>CDDDDDDDDCDC
@2YE
GTCTGCCCCAAAGAGGTGTACGATGTCATGCTGGGGTGCTGGCAGAGGGAACCACGGCAGCGGTTGAAGAAAAAGGAGATCTACAAAATCCTCCCTGGTTT
+
???BB;2BA<DDBED;EEE<??+AC?CE??E@BD;6000B?D6?;686@'.(5(-(-,9>@3''8,(,(((((+0((8((+4:((+(8A>((4((+((++1
@2YF
CGGGAAGGACCCACATACCAACGGCGAGGATCACTTCAGCTCTGGCAGTTTTTGGTAGCTCTTCTGGATGACCCTTCAAATTCTCATTTTATTGCCTGGAC
+
???DD6A:CDDDAE+2ACE?FFB8C08D6'B)(.8)87)7).@7?A>5.;;@?@@(55;>A;;555>3(:>:A??A<>A:>:A>>A>>BA:>AA>4(:<12
@2YG
GTCCACGGATCCAGAAACAAGCCCACCAGCTTGTGGAACCCAACGTACGGCTCCTGGTTTACAGAGAAACCCACCAAAAAGAATAATCCTATAGCAAAGA
+
@@@FFADFHDFHGIJGJIJJJIIJIIGHJJIJIGHIIGGIJFIIGCFIIBGEEHEFFFDE>>CEDCCDDABDDDDDDDBDDDDDDDEDDDDDDED@@CCC
@2YH
CTTCAGCTCTGGCAGTTTTTGGTAGCTCTTCTGGATGACCCTTCAAATTCTCATTTTATTGCCTGGACTGGTCGAGGCATGGAATTTAAACTGATTGAGCC
+
@??DD;;DHDFBFDCHEHEGEHH<HEBHEFE>BC9???CDGEGDFHGGCG@D?DDFBHBAFIIGH;2=@=DHIB<?D<;;=;;5;>C>>:>>C>ACCCC@?
@2YI
CCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAAC
+
C@@FFFFFHHHHHFIIGFIIJIIJIIIJJGIIGIIJJHJJJJJJJHGIIIGIIIJIHIIEGIJJIIIJJHHHHFDFFFEEEECECDDDDDDDDDCDDDDDC
@2YJ
CCTCTATTGAGCTGCTGGCCCGCTCATTGCCAAAAATTCACCGCAGTGCATCAGAACCCTCCTTGAATCGGGCTGGTTTCCAAACAGAGGATTTTAGTCT
+
?@?DD:ADHBHHHIEBGHFEGAEGGE@DCG>B>GGGGIEEGHIBB>(=CHGGGIIG@EH<ADDFDD;>CECBBBBB?AA@C@ACA<9?C?BC>AC:<:>C
@2YK
TGAATCCTGAAAGAGAAATAGAGTTTAGTGCTTCAAGGGCCAGGCTGCCAGGCCATGTTGCAGCTGACCACCCACCTGCAGTGTACCGCCGGAAGCACC
+
CCCFFFFFHHHHHIJIGJJJJJJHIJJJIIJJJJJJJJJJJJJJJJJBHIIJJJJJJJGIJJJJJJIJJGHHHFFFDEECECCACEDDBBDDBDDDDDD
@2YL
CCACTAATTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGA
+
+:++??+<>B@C=+?7AAAA=3+2+**@=A=<7AAB>75=*=79=<*9=4=)=<AABA=;-(.7)=A9.6;)))'939';;:59=9(5;;=3;95;0528
@2YM
CAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGGGAGTTGCTAAGAGAGAAAACCAAATAAGAATG
+
1:=:;;=3+CCFFEF<<<CCC+<F?FD3C:?CG9??DFFE@@@FB9*9??F9?F<88@4;AE45AE96(5=,;;ABB;>@B:<<@A>9(<888@::>ABBB
@2YN
CAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACC
+
@CCFFFFFHHDHHGIJJGIFJJIG?FHI@FEIICIGIJEIIIGIGHGIJIJEHIICCEEHEHEFFDFCDCEEDCDBD2=>>C<>CDCD>ACCDDDDDDEDC
@2YO
CAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACC
+
CCCFFFFFHHHHHJJJJIJJJJJIJJJJHIJJJJJJJJJJJJJJJJJJJJJIIJJJIJHHHHHFFFFEEEEEDDDDD=@CCCDCDDDD>CCDDDDDDEEDD
@2YP
CCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGT
+
CCCFFDDFHHFFHIIHJJDGIIIJJJJIIIIJJJJIIIIJJJJJJJEHHIEDECHHHHFFFFFFEEECEDDBD@CCDDDDDBBDDDDDDDBDDDDDDDBDC
@2YQ
CGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTT
+
??7BDDD;8DD3DEECBEB?3ABECFE@D?EBEBDDB<DDDEDB?D@>DIDBBB*.<@AAADD;@D@@AA@AA????>AA,>?==3)34(2>:>9<(9>>A
@2YR
GATCTCTGAACTTCGGCAACAGAATGATGAACTGACCACTTTGGCAGATGAAGCTCAGTCTCTGAAAGATGAGATCGACGTGCTGAGACATTCTTCTGAT
+
@@@DFFFFHHHGHJJIJGIJJJJGIJFGGHIJGIIJJIIIIIJJJIHGGGIIJJJJJIEGHGGJJIIIHHHFHHHFFFDDBBBDDCBDDDDDDCDDCDEE
@2YS
CAGAAGTCATCAGAATGCAAGATAAAAATCCATACAGCTTTCAGTCAGATGTATATGCATTTGGAATTGTTCTGTATGAATTGATGACTGGACAGTTACCT
+
:=;+:B2ADDADDEB4A9F:3+<E+<<FFIBE?*1CEEECDDFE<9??*?:9BD@B9DEEDEIECC:=8/B@:=C=C<44@>@4A?7)=7?767;>(66>@
@2YT
GCAGTTTTATGATGACACCTGTGTTGTCCCAGAAAAATTCGATGGAGACATCAAACAAGAGCCAGGAATGTATCGGGAAGGACCCACATACCAACGGCG
+
??@?:BDEHGHHFBAGGGAAHHEE>GCHGBHHCBF>FFHEGGHIB*9BDB?<DGG*=8B@=@FHII<>@CAHHFEBD=<55((5<<?<CCCAAC??B39
@2YU
AAGCCACAAGTGGGAATGAGGCCCTCCAACCCCCCCACACCATCCAGCACGCCAGTGTCCCCACTGCATCATGCATCTCCAAACTCAACTCATACACCGA
+
CCCFFFFFFHDHFIJJJIIJJJIHIIIJIHIJJJJIJIGIJIIHHHFHFF8ACCD>A@CDDDDDBDCDDDDDCCDECDDDDDDDDDDDDDDDDDDDDDBD
@2YV
CTCCAAACTGAACTCATACACCGAAACCTGACCGGGCCTTCCCAGCTCACCTCCCTCCATCGCAGTCCAGACCAGATAGCAGCTACCCCATGGACCAC
+
;(-55).88)<4))296@<89)(@=4589(83<39-=43)=?36:7:369>9.(-.;3).6,(5'933;(((,,(((,(822(+82:<<<((+8(++8
@2YW
CCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTT
+
????BDDDDD82:CEEE@AD?+<2A@C8C*19?B?DE?DD>D?D?A;AD;7AAC7=C;C;??D??@A(55-5(5(:;AA?:=AAAA:>3>A>9(22)55>
@2YX
CTAAAACAGACACATGGTCCTTTGGAGTGCTGCTATGGGAAATCTTTTCTCTTGGATATATGCCATACCCCAGCAAAAGCAACCAGGAAGTTCTGGAGTTT
+
?@?BDDDDFDHHFHIIIACGCHHHF<FAA@CBGIIIIIIIGIIIIIIIIIGGHGGI@HGGGGIBFEGEGHHIGIDHGF;@D;@ACCCCBBC@C>>@ABCCC
@2YY
CTTCGTGTTGGGCCAAGGTTGATGGGGAAAGGAGACATTGAACAAAATAATGGGGCGGGAGATCCGACTGAGGGGGAGGGGGGAAGGGCGACAACCAGT
+
0(---)22(.(0(3(((()2)2)22(((((:(((6;9))7))0.).(.))))/.(-'')5&)((((+)0&(+253&0&&&05-&&(+0:&&)&)(+8++
@2YZ
CTGGGAAGCGAGCTCTAGCTGGAGGTCCAGCCCCTACTGAAAAGACACCCCACTCAGGAGCTCAACTTGGGGTCCCCAGGGAGAAACCCCTAGCTCTGGG
+
@@@;DDADFDBFDFGGE<?+AGDFFD?@D?*6?@BD?@FFFF<B;8BBFEE5-=CECEAB?B@;A;>>>@B@'8?BBB@BB<BB<A>88@<?<>:AABAB
@2Z0
CTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTAT
+
@@@FFFFFHHBCHED?FBGHHGIGIHG@DHGEHGHIIIIIIA<FGIICD@EH?EACHDFF@@DC@CEDBBDC@>C@@:;:CDDCAB?BBDD@BBBDAB9@:
@2Z1
GGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTAC
+
@@@DFFFFHHHHHJJJJJJJJJJJJJJJJIIJJJIJJJHIIJJIJJGJJJIJJJJJJIJJJHHHHFFFFEEEEE@DEDDDDDDDDDDDDDDDDDDDDDD
@2Z2
TTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGC
+
CCCFFFF>FHHHHIIHIIJIJJJIJJJIJJIIGIIJJJGGHIIJJJJJEIIGIIJJJGHJGJJHEHEEFCFEDDE@CCEEDDDCDDCDDDDDDDDDDDB<A
@2Z3
TGACTGGACAGTTACCTTATTCAAACATCAACAACAGGGACCAGATAATTTTTATGGTGGGACGAGGATACCTGTCTCCAGATCTCAGTAAGGTACGGAGT
+
@<@DDEB>CFHFDHGIIHEIJJJGDHIIIGIGIGIIGJI=FGIJFEGHIIJHIHIJGHIIIDGGFEFDDEEDB@A@>ACCCCC?@C@CCCDCCDCD>BBD?
@2Z4
CCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTTATGGG
+
@@@D?BD:F;C?D::C?FG+<?3C<?CFHCF>GDFFGE<BF>GB9FDDBF>:AA=CEI;CE>EAAEE/,,3=5;;?=@;=8<AB>::>@BB(09@@4:@BB
@2Z5
GCATGGATTACTTACACGCCAAGTCAATCATCCACAGAGACCTCAAGAGTAATAATATATTTCTTCATGAAGACCTCACAGTAAAAATAGGTGATTTTGGT
+
?@@DDB?:AFDBDBGFDEF;8@F<<AEAGBCFGCEE@DFFBDBB<00/?00//=8=BC4==CCDFGD7==C7==?AE3?;7B>7;>>@>;ABB;5>AA;3,
@2Z6
CTTGAAGAACAAGACCACTTATTAGAAGATTATCAGAAAAAGAAAGAAGACTTCACAATGCAAATTAGTTTCTTGCAAGAGAAAATTAAAGTATATGAAAT
+
CC@FFFFDHHBFFEHHGIAHIEHIHIIIEEEGHIIIIGGIIIIGIIIIIGIIIIIIIICHIIIIIIIIDEGCHGIEEEE>BCDFDEEEECE@CCDEEDECC
@2Z7
TGATGACACCTGTGTTGTCCCAGAAAAATTCGATGGAGACATCAAACAAGAGCCAGGAATGTATCGGGAAGGACCCACATACCAACGGCGAGGATCACTTC
+
CCCFFFFFHHHHHIGIIHIIJIJJJIJJJIIIIIJJEGJIJJIIJJJJJIIJIJJJJJJIJJJJJJHHHFFDEEDDDDDCDDDDDDDDBDDDDDCDDDDDD
@2Z8
GAGAGCTCAGGGACCCAGGCCGCACCAGGAGAACAACCACCAGGAGTCCTACCCTCTGTCAGTGTCTCCCATGGAGAATAATCACTGCCCAGCGTCCTCCG
+
CCCFFFFFHHHHHJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJIJJCGIHHHHHFFFFFEDEEECEDDDDDDDDDDCDDDDEDDDDDDDDDDDDBDDDDDD
@2Z9
CTACCACATGCAGCCAGTCACTGCACCTCCATCCTACACTCCTACCAGCTATTCCTCTACACAGCCGACTAGGTATGATCAGAGCAGTTACTCTCAGC
+
<<953):>1><?44(8<<;>?;???<9><5>@8(<>9)9?<<??<>>>>??;9=;>)9=)<)<1:=9=?/;7)88(.6.6.97;0:;7:5(7;;:<=0
@2ZA
CCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGGAGCATG
+
;:?BDBDA:A3DFB@GIFIF;EGB@DFBF>@?:4?<FC?DGEEEGCED@C>B?BFCFEF4;BBE<5??B=;@>6>@BBB83'8?9<?<(209@B(<8?B:@
@2ZB
TGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTAT
+
CCCFFFFFHFHHHJJJJGIJJJJJJJJIJJJJJJJIEHJIGIIIGGIJJJIIIJIIJGGIIGHHFFFEEECEEDDDDDDDDDDDDDD9CBBDDDDD:CCD
@2ZC
CTCAATTAGAACAGCTCCAAGAAGAAACATTCAGACTAGAAGCAGCCAAAGATGATTATCGAATACGTTGTGAAGAGTTAGAAAAGGAGATCTCTGAACTT
+
C@@FFFF;DFHHHJIBHIIJIIIJJGIHIJIGGIG@G<DDGCFGGIFIGGHGGHGHGHGIGIJJJIG@DH;CHHFCDC@B@DFDEEDABBCADDDDDDDDD
@2ZD
CTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCT
+
CCCFFFFFHHHHHJIJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJIJJIJJJIJJJIJJJJGGIJIHHHHHFFDDBDCDEEEDDEDECDDCDDDDDDDDC
@2ZE
CCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTTATGGG
+
CCCFFFFFHGHHHIJJJJJIJJJJJJJIJJJJJJJIIJJJJIJJJIJJJJJJJJJIJJIJIHHHHHHFFDDDDDDDDDDDDDCDDDDEDDD>><BDDDDDD
@2ZF
CTGATGGACAGCAGATACTTGTGCCCAGCAATCAGGTGGTCGTACAAACTGCATCAGGAGATATGCAAACATATCAGATCCGAACTACACCTTCAGCTACT
+
@@@FFFFFHGDHHIIGGIIICHGIIIDGHIIIHFGICDG@F>FHBFHGHIHCGGAEGCAGEGHIIIGHHEFHEFFFFFFDEDD?BBDCDDDDDDDDDCCCD
@2ZG
CTCCGAGTCCCACCCGAAGCCATCCAGCCCCCGGCAGGAGAGCACACGCGTGATCCAGCTGATGCCCAGCCCCATCATGCACCCTCTGATCCTGAACCCCC
+
>==7AA8AA?+2+@)@A<):1@<?=A*?=?)8.<A4=45(5==>;).'9937=5;395==;3(+++3:(+225;83=3:83:;=7++:???=:?:::8;=9
@2ZH
CGGCGAGAAGCTGGGCCGCGTGGTGCACATCATCCAGTCACGGGAGCCCTCCCTGAAGAATTCCAACCCCGACGAGATTGAAATCGACTTTGAGACCCTG
+
CCCFFFFFHHHHGIJIIJJJGHIFIJJIJJIIIJJJJJJJJHHFFDDDDDDBDDDDDDDDDDDDEDCBDDDDDBBB<BDDDDDDDB<BDDDDDDDCBDCC
@2ZI
GTCTGGGAAGCGAGCTCTAGCTGGAGGTCCAGCCCCTACTGAAAAGACACCCCACTCAGGAGCTCAACTTGGGGTCCCCAGGGAGAAACCCCTAGCTCTGG
+
??=;B3B?DHFFHEGIIIDEHIII38CC?CDHDGH>FHGGI?DHIGDBFFCE8DBEFEEBBDECCCCC@CC=@B:?ABB<?@BBBBBC??@BBBCCCCCCC
@2ZJ
CGGGAGCCGGGTGGATGTGTGTGGGGGAGGGTGGGGGGAGGGTGGGGAGGGGGAGAGGGGGGAGGGGGGACGGGGGGGGGAGGGGAGGGGGAGGGGGGGGG
+
0-02(<(((-:((23).)..2(.(((('''-((',''&&&0&((0)&()&)00&&&+(0&)0&)55-0&)&)&&00&&)&&)&&)&)&)05))0855&5-&
@2ZK
CTGTGTTGTCCCAGAAAAATTCGATGGAGACATCAAACAAGAGCCAGGAATGTATCGGGAAGGACCCACATACCAACGGCGAGGATCACTTCAGCTCTGGC
+
?@@ADD>AD:CFHIHGIGIGC>FE?B?AFFB?CGGDGHBDGABBCAGIGCHI8=8=@FH>8EC=ABB?;=>>ACA3;@B=?&9@-3>89>CACA:>CCC@3
@2ZL
GTGGAGCCATACTTATATGTAGCAAAACTACTGTAGAGCCCACACCTGGGAAAGGACCTAAATGTGTATATAAAATCAGCAAACTAATCAAAGCTCATGAT
+
(0-((()()=)<4)2)))))3.)3=)):@4=>):)2=);.==17-(0.1(7<13=17()89=)8=.>;>8;)<36))8)6)))6((.(.:-:477(4;;(,
@2ZM
CCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCAC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJHIJJJJJIJJJIJIJIIJJJJIJJJJJJJJJJJHGGFEECFFEEFEEEBBDBDBBDBB
@2ZN
CAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGCACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTC
+
@?@FFFBDHHFHDGBGHGGGIIHHIGH<;@?CFHB<93?BDBFHIIIGC1(0=FE8=@=FE@EAHEEA7?@DCCCAEAC:ACCCCCC<ABCCCBCAABB>B
@2ZO
CTGCGTGATGTGCTCTATGAACTCCTTCAGCATATTCTGAAGCAGAGGAAACCTCGGATTCTTTTTTCACCATTCTTCCACCCTGGAAACTCTATACACAC
+
@C@FFFFBHFFHHJJIIIIGGGHJJIJJJJGIJJJJFGIIEIGHIIIGGHIHIIGIIFHHGIIIJJHHHHHFFFEFFFECEEDBCDDDDDDDDDDEDEDD>
@2ZP
TATAAAAAGAAGCTAGAAGACCTTGGTGATTTAAGGCGGCAGGTTAAACTCTTAGAAGAGAAGAATACCATGTATATGCAGAATACTGTCAGTCTAGAGG
+
C@CFFFFBHDDHFIGIGEHGH@GEE?2AF@GGIGGD;@G6F@F=@GHI;@AEC>?;?>7@DBCCEEE;@@>ADEDC;@>C@:?@C:A;>>>>>@C>A>C?
@2ZQ
GCCGTTCACTCCGCTATTACTATGAGAAAGGAATTATGCAAAAGGTGGCTGGAGAGAGATATGTCTACAAGTTTGTGTGTGATCCAGAAGCCCTTTTCTCC
+
@@CFDDFFHHHFDIJIJGIHIIGDGIGIIJJBHGHJIIFIJJJII?BDHHJIGIGGGEHGGG=EGHHFHHF@DEB6?@AA>@DDCCDDDCDBDDDDDDDCD
@2ZR
ACAAGACAGAGCCGCAGTCGGGCGAGGCAGACCCGAAGCGGGAGGGGCGCAACCTGGGGGTGAAGGAGACGCCTAGAATGGACTTCGGGACGGTGGAAAGG
+
((0@-16@949.:((8-2.((:-(((-'(((.((''',,',92''&0&)0&)0(362(00&0(+(++(/((50(&(((3((+((((()&0&&)0858(28(
@2ZS
GTGGAGGCTGTCATTCAACCTCAATTTCTTGCAGTTTTGCTGTCCCCAGAAAAACAGAGCGATCCCTTGGCCTTAATTGTGGAGCGAGAGCAAGAAGAAGG
+
3--8@(<(2(9.;@>=:)39=>1=.<@1@))@:)1@)>(=?<:))07)(<<))((.99>)''6=())6:9>;;;)).:(((789(',2'2(((((+((+(2
@2ZT
GGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTC
+
CCCFFFFFHGHGHJJJJIJJJGIJIJJJJJIJJIIGIJJJJJCHEGIGIJJHIJJJJFGGJJJJIJJIJHHHHFFFEFFEEEEEDDDDDDDDDDDDDEEDD
@2ZU
CCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGC
+
CCCFFFFFHHHHHJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJIJJJJJJJJJJHHHHHHFFFFFEEEEDEEDDDDDDDDDDDDDDCDD
@2ZV
CTCAAGTAAAGGCCAACCAAGCCCTCGAGCAGTTATTCCCATGTCCTGTATAACCAATGGAAGTGGTGCAAACAGAAAACCAAGTCATACCAGTGCTGTCT
+
CCCFFFFFHHHHHJJJIJJJJJJJIJJIJJJJIJJJJJJJJJJJJJJJIIIIJGIJJJJJIJJCEH?EHHHFFFFFEEEEDDDDACDEFDDDDCCDEDCDD
@2ZW
CCCAGAGATTTTGCATATGACTCAGAAGTGCCTAGCTGCCACTCCATTTATATGAGGCAAGAAGGCTTCCTGGCTCATCCCAGCAGAACAGAAGGCTGTAT
+
CCCFFFFDHHHHHJJJJIJJJJJJIIJJHHIIJJJJJJJJJJJIJIJJJIJIJJIJJJIIIJJJIIJJIJJJIIGHHHHHFFFFEDEEEDDDDDBDDDBDE
@2ZX
CTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATG
+
?<1=D?;DFB;D?@;A:BF@E8@BGHIGEHC<@9?FDFDHEDBH<;4'6@E<=?BC>DBCCC;ACCD;A=A@?CBB@??B??C>:>@??C@BB<<>9:444
@2ZY
CCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGAC
+
C@@DFDDFGHFFAGEHIIEGHIIIJJIJJGIBDHGIHHGCHIJJGIJIGG88C<CGGGEHGDGEICFFGEBEF>DCCC<>>@==BDBCBCECACCDED>D
@2ZZ
GTTCATTCCTTCCGATGTTGACAACTATGATGACATCAGAACGGAACTGCCTCCTGAGAAGCTCAAACTGGAGTGGGCATATGGTTATCGAGGAAAGGACT
+
@@@FFDFAFFHHHIHHGHHHJIIJIJIJJIJIJGIIIJIIJJJJJJIGHIJJIJGJJJIEIJBGIIIGEHHEH?BDD@CEEEED@>ACCDDBDBDDDD?BD
@300
CAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCC
+
@@@DDDFDHGAHFIBBFGIIIEGIIIIIIGGGIIEIIICHGI?HGGEGIIIGIIGIIIIHHHFHEEDFDCECACBBCBA@ACCCECCCCCCCCCCCCB@BB
@301
ACCAAGTCATACCAGTGCTGTCTCAATTGCAGGAAAAGAAACTCTTTCATCTGCTGCTAAAAGTGGTACAGAAAAAAAAGAAAGAAAAACCACAAGGAC
+
=;=AAA<AABC<=B><==ABBA7A>BBC3A>BB;ABBAAABBAB>BBBB>ABBBA>ABBBB>A/8A)=>)=>A>BBA@@===>;;=======;82892;
@302
CAAAACGTCGGGTGCAGTAACTTGTCTTCAACAGAAACACACACCTCTTCTCCTTTGCCGCTGGGGCAGCCATTGGCCCGGCGTCCCGTCGTGACACAGCC
+
;519(2((2(=(=3(4)).)).9)):))8))..(.)):)9=(('-).:).)).)8;;)3:=8''(,'''((((,(,,(()&)0&&&)0(()5&(+(+((((
@303
CCGTCGTCTGCACGCAGCCCAAATCCCCATCCAGCACGCCAGTGTCCCCACTGCATCATGCATCTCCAAACTCAACTCATACACCGAAACCTGACCGGGCC
+
@@CFFDADHHFHHHGHIIIIGHGIIHGIGGIEGIIIEBEHGIAHFHHBGDEHHEHFDEDFBEFEEEDEDDBCCCDCDDDCCACDCBB@B>?CDD?CBDD>>
@304
ACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTC
+
@CCFDDEFHHHHHICHEHIJJJFIIJGJJJIIBGFHIEHGFHGIIA<DDGH=EFCE@?@;BEE>>C>ACDD@DD>5A@@@A>@@>@@>ADBBBBDB?AB@A
@305
CAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTC
+
CCCFFFFFHHHHHIJJJJIJJJJIJJJIIJEHIJJIJJJGIIJJJJJIGGBFHIIJJJJJJJIIJJHHHHFFFFFEECEEEDDDCDDCDDDDDDDDDDDCD
@306
GCAGAGAATAGCATTCTTAAAGATGAAAAGAAAACCCTTGAAGACATGTTGAAAATACATACTCCTGTTAGCCAAGAAGAAAGATTGATTTTCTTAGACTC
+
@CCFDDEFGFHHFIJJIIJJJJCHHIJJIJIJJJJIJJJJJIIJJJGIIEIIIJJIJJIJJJIJJJIGHJGGJJJEFHHHFFFFFEECDCCCDDDDDDDCD
@307
GAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCC
+
@@BFFFFFGHHHDHIIJJJJJIIIJIJIJJJJGIJIIJJEGGJJIJIHIIHHGEEGFFFBAEEDDDC@BDDBDDDDBBDDDDCDDEDDDCDDDDDDDDDDD
@308
TATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAACCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGG
+
7=1<<4A3+?;C+23+<)7?<0=@=81))::700==??>**0(75='(5'-(;(.77;;(66.535;;;;;=(5;65589(:33:=8;==<798338?(((
@309
CTCTGTTCGAGTCCCTAGAGGGCCGGCCGTGGAAGGGGGACACGTGAATATGGCATTCTCTCAGTCCAACCCTCCTTCGGAGTTGCACAAGGTCCACGGAT
+
CC@FFDDDHHBHDDDHHEHIGG>FEBHGF@DFFHIIAH@<?=BBABDDDDADC?ACC@@C>AAC:@@CCCDB?B?CACBD8<?AA>@:@ABB:>CCCBD>5
@30A
CGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCA
+
?;8:BAD@<DB?FDEH<FGI4C<8C:CFHGGGA:DGEBCB=FHIFA@GGGHG2@=CEE9CDCCBB???BBBBCCACCC@@CCCCCBB@B@8<@?<@8AC
@30B
GAAAGACAGAAAAATAATTCTGTGGGATCATGATCTGAATCCTGAAAGAGAAATAGAGGTTCCTGATCAGTATGGCACAATCAGAGCTGTAGCAGAAGGA
+
=??D1B32=DD>DAAEE@FC4EACE@<22@*?*CEDFD><DDCA4?BD*099D*9/09(.8BB488)7)=)7)=C9C>;A)7A3).6.;6;;;A;,;(5<
@30C
AGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCAC
+
CC@FFFADHHFHDHHGIIECFEEBGHGFHGHHIGIGHI>F?<DBFHFFDHGGIHGIIEHHEIIIIHHGD;?BCBCECCCDDCDDDDD@C:@A>AA@@CDDC
@30D
ACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGT
+
CCCFFFFFHHHGGJIIJJJJJJJJJJJJJJJJJJJIIJJJJJJIJJIIIJIJJJIJIIHHHHHHFFFFFFFEEECCDDDDDDDDDDDDDDDDDDDDDDDDC
@30E
TCCAAATCCAAAGACTCTGTGTGGGAAAAAGAAATAGAAATACTTATAGAGGAAAATGAGGACCTCAAACAACAATGTATTCAGCTAAATGAAGAGATTG
+
@C?DFDDDFHFDHHIGGHHCHHGIGCHGGGIGGGHG@GHIIJIGGIDEHHIJHHIJEHIII;FEAGHIIGE?EEFFFB;BC3>A;@CCDADDDCCBD@CC
@30F
CGGGACTCGAGTGATGATTGGGAGATTCCTGATGGGCAGATTACAGTGGGACAAAGAATTGGATCTGGATCATTTGGAACAGTCTACAAGGGAAAGTGGC
+
@@@DFFFFFHH:CGFGIGHGEGII<CFGB>EDFHGGIGHGGIIEGGGHIGEGFHCHHIIIIGGCHHFHEEFDEFFFFCEECCCCCCCCCCBB<?BB@CC?
@30G
ATAAAAACATTATGACCAAAGTGCACGGCAAAAGATATGCTTACAAATTTGACTTCCACGGCATTGCCCAGGCTCTGCAGCCACATCCGACCGAGTCGTCC
+
@@@DDEF<DHFHBEF@FEGGEEAF?F=EBHIIIGHGC<DHACCHFGGDDDFFEHCHBCFGBBE=EEFFFEE=A@@ACC@?CB?9?AA92?@B@998<<?BB
@30H
CTTAGAAGAGAAGAATACCATGTATATGCAGAATACTGTCAGTCTAGAGGAAGAGTTAAGAAAGGCCAACGCAGCGCGAAGTCAACTTGAAACCTACA
+
@CCFFFFFHHFFHJJJJJJJIJIJJJJJJJJIIJJJIJHIJIIJJIIIIIIIHIGBDGIIGIIHIIJJJIGIHHFFDDDDDBDEDDDDCDDDCDDDDD
@30I
CACAAGGCACACCTACACCCCTTATCCCCATACTAGTTATTATCGAAACCATCAGCCTACTCATTCAACCAATAGCCCTGGCCGTACGCCTAACCGCTAAC
+
?@;D4=BDC;CCFDG?C<:CEGFF??E?C@GEGI@?DCFG<?B40?F?:=BFC8888=CE;=;CCC=7==;?3;);;;AC9??6?@BB=@B<A2+05.0&+
@30J
CAGGAATGTATCGGGAAGGACCCACATACCAACGGCGAGGATCACTTCAGCTCTGGCAGTTTTTGGTAGCTCTTCTGGATGACCCTTCAAATTCTCATTTT
+
CCCFFFFFHHHHGIJJJJJJJJJJIJJJJJJJJJJJJJJJHGHHFFFFFDEDEEEEDDDCDEDDDDBDCDDDDDDDDDDDDDDDDDDDDDDDDDEDEEEEE
@30K
ATCGACCTTTCCTTTCTATCCCCAACCACCCCTCAACCCCTGTTTTCCCCTGCCTTCCTTGCAGAGGCCATGGAGGACGAGGAGAGACAGAAGAAGCTGG
+
CCCFFFFFHHHHHGEIIJIIIJJIGIJJJGHGIIIJIIGGIJHHIGEGHIIGIGIFCCGHGGHHHFFFCDEEEDDDBBB=BD@BBD@CCCDCCDD?CDCD
@30L
CAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCC
+
@@@DFFFFHHHGHIJHIIIIEIJJIJIIJJJIIIIJJIAFGIIIJIJJJHIHIGDCEHIDHHGDED?BE>@BCDD?CD@CCDEDACDCDDCDDC9ACDDDD
@30M
CTTTCGCTATCGATCTCCTCATTCAGGTGATGTGCTCTATGAACTCCTTCAGCATATTCTGAAGCAGAGGAAACCTCGGATTCTTTTTTTCACCATTCTTC
+
@@@=DDDDHHHHBEHIIGIIIFBHBFA?FAGGHECGGCHGGEGHIIIIIIDHBHGIIIEIIIIGIIICGIIGGAAEEBDDA>CCDCCCBBCCCCACCDA@C
@30N
CTGGAGCCACCAAGAAATTGTCCTGATGATCTGTGGAATTTAATGACCCAGTGCTGGGCTCAAGAACCCGACCAAAGACCTACTTTTCATAGAATTCAGG
+
>==AA?@1@@C++@?;ACA+3?A7?C?B;9A>A4?@?3?>AABB<**0=5=09A4/=1;>2=ABAB3==A'9/6==((((5;3;:??=5(5;((,:(,83
@30O
AGTGGGTCCCATCAGTTTGAACAGTTGTCTGGATCCATTTTGGGGATGGCACCAGAAGTCATCAGAATGCAAGATAAAAATCCATACAGCTTTCAGTC
+
1+1=+B=DDAC+<<A<C@FA:ADFFB92ACEEC9?BCDBB@D):@88BB)8B@C=C@D8=;A;CC>CACC:=)777;?3>;@@3.-,>;5;;(,:5,>
@30P
TGAGTATCAGGAAGGCTGCCAGGGACTGGGCTCCAGGGGCAACATTTCCCTGGGTCCTGGAGAAACCCTAGGACCTGGGGATACGGAGAGCAGTGTGATTC
+
=?@DBDDDDDB?FF:3C;CHB>??<AC@;@FBBDGHDDA<?BGBHAHIGIE=@C)7CGGCCCCDEB?B@A>3;>;;?@BB<8?CBB@B&<<>?(:4@CA>:
@30Q
CACATACCAACGGCGAGGATCACTTCAGCTCTGGCAGTTTTTGGTAGCTCTTCTGGATGACCCTTCAAATTCTCATTTTATTGCCTGGACTGGTCGAGGC
+
@<=?B;?:?CF?FI:?:8DBG;9?FDDDBDBB?)BFC8@FCCEAFF>?E@;=7)7;)766(>ABA;@@A>:3,,;>AB@A@B::((:8?8481+45<5<5
@30R
CCGACGTTGGGGCATTCAGAAAAACAGGCCAGCTATGAACTATGATAAACTTAGCCGTTCACTCCGCTATTACTATGAGAAAGGAATTATGCAAAAGGTGG
+
@@@DDDADDHFDHJJIJJJJJJIIIJGIJIJIJJIJJIJJIJIIJGIJJGCHHIGIJJHHCEEFFFDDDDDDDDDDDDDDDDCBDDCDDEDDDDCC?@>CB
@30S
AGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGG
+
@@CFFFB,ACCFHIIIIIIIIIIIIIGHIIIGGBFHIGEHGFHEIBDBHHIIEGGIGIIICHCHHIIHHHHEBAC@CBCCCCCCCCBBCCCB>ACCCDCCC
@30T
GAATTGAGCTTTTCAAGGGAACAGATTCAGAGAGCTAGACAGACAATAGCTGAACAAGAAAGTAAACTTAATGAAGCACATAAGTCCCTTAGTACAGTGG
+
@@@FFD?DFBFHDHIIIGIGGDDEGBHHGIGGGGIIIFIGGHBFGIEHEBF?DGEI@FHGCCFFHIIIGIICADHHFE<@CDEFCDCCCC@CC@DDEDCD
@30U
CTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTAT
+
?@@DFFFFDDHHDGJJJBFIEHHIGEIIIIJGGFHIJJIIIHIEGDHAGCGE7?EFFFDFFEFDCAE?BDCDDDCDCC@CDCDCDDDDDDDBD?@CDDDDC
@30V
AGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACC
+
CCCFDFFFDFHHHGGJGIJIGIEHHHEFHIJIG?@GGGGHCGGIGGIIJJGGHHGFFFFFC>ACEEEDCCCDBDDD?BDDBB??CDCCBDDCDDEDDDDDD
@30W
CTCCCCGGCTGAGAGAGCTCAGGGACCCAGGCCGCACCAGGAGAACAACCACCAGGAGTCCTACCCTCTGTCAGTGTCTCCCATGGAGAATAATCACTGCC
+
@@@DDFA?FFFHFIIIIICGIIGC@FG@GIGHCABHGGIEHGE?A>@D?DCACB?BB?;ACC@CBB>?<A>C@C>@AC:CCC?CACC?AACC>CCCC>@CC
@30X
CCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGAC
+
@@@?DDFFGGHGGIIJIIJJJJJJGIIGIJJEIJGGGGGHIII@GGHGIH@FHIIJGCIEGEHEBEEBEEHDFCDC@BBB@BDDDDEDEEDCDDDDBDDBB
@30Y
GGACACACCTTGCTCCCCATTCGCTGGAGGCCTCCTGAAAGCATCATGTACCGGAAGTTCACTACAGAAAGTGATGTATGGAACTTCGGGGTGATCCTCTG
+
1+1=?BDDA+<+AG4:CAGIH>3@EB6F)1?:DDEFFIE99;9*90*./=FFB'4;ACCE=AC3;?:B).(..6((.5(-;((-(5352'&&&24(+>:(+
@30Z
GAAAACACTTGGTAGACGGGACTCGAGTGATGATTGGGAGATTCCTGATGGGCAGATTACAGTGGGACAAAGAATTGGATCTGGATCATTTGGAACAGTCT
+
C@@FFFFFDHFGHBHGIJIIGFHIEGICFBBGFGIIJICGFGHIIIJDGIIJJJJIIGIJJIEHHGHDBFECDCCEDDACCCCDC>A@DEECC>@ADDDDD
@310
CTACTGTAGAGCCCACACCTGGGAAAGGACCTAAAGGTGTATATCAAATCAGCAAACAAATCAAAGCTCATGATGGCAGTGTGTTCACACTTTGTCAGATG
+
@@@DDFBDFFFHHEIIGEFDFEGEGHGG@???BB3DD:BGHIEHIGHIADGDFHFI;FGH;.@C@E>==?CA>AEFF@B;@6@CECE@>@CDACCACC:@>
@311
CTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTAT
+
CCCFFFFFHHHHHJJJIJJJJJJJJJJJJJJIJJJJJJJJJAGGJJJGIIJHEHHHHFFFFFFDEEEDDDDDDDDDDDFDDDDDDDDDDDDDDDDDDDDDD
@312
TGCAAAGAATAAATCCAACTACAGTGAAAATGAAAAGTTCTGTCTTTGATGAAGACAAAACTTTTGTAGCAGAAACATTGGAAATGGGTGAGGTTGTTGA
+
=??D1ADBC?DD:ADE@BEA3FEIEEF<FDEE999*?@BBBB:DD9BDDDD>9B<?DDDD;8BBAC88AA@C9=77A>=>DA377;A@D@9;A;=>;=?:
@313
GAGTTGGCTGAGCTGCGAGGTCTGGCAGCCGGAGTAGGCCTGGCTAATGCCTGCTATGCAATACATACTCTTCCAACCCAAGAGGAGATTGAAAATCTTCC
+
@@@DDD?AFHHFBFGBDFEGFCHIG@F@DHGEGBGHIIIHCDC>FGGH@GEEECECE;?CFFFEEEAEACCC>CCCCDDBDB9??8<8?>ACDDDDDDC>>
@314
CAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTC
+
CCCFFFFFHHHHHJJGHIJJJIJJJJEHIJJJJJJJJJJJJJJJJJJJJJJJIJIJJJJJJJJJJHHHFFFFFDEEEEEDDDDDDDDDDDDDDEDDDDDD
@315
CGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTC
+
@BBFFFFFGGHHHIJJJJIJJJJJJIIHIJJIJJJJIGHJJJIGIIJJJJJJJIJJJJIJIJJHHHGFFFFFCCDDBBBCCDDEDDCCDDCDDDDDA@BBD
@316
AAACAAGCCCACCAGCTTGTGGAACCCAACGTACGGCTCCTGGTTTACAGAGAAACCCACCAAAAAGAATAATCCTATAGCAAAGAAGGAGCCACACGAC
+
===AA8A=;33+<AAA+??AAA@CA?0)??;05=<AA<<<ABB>AB>7=3>A;AB=6;1<==;<=@=1(5;=?;>;:9399;3;=?;7;9;<<9;<0..9
@317
GGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTT
+
@@@BDDFFFFAFHBHIIJCGIJJJJJJGIIGHIJIGIIJJJGHGIJJJJJJJJJJIEHIJIJIGGIHGCEEHFEFDFACBDDDDDEEDCCDCDCCCCCCAC
@318
TGTGGAACTGGAAAGTGAAATTTCAACCACAGCAGATGACTGCAGTTCAGAGGTAAATGGTTGCAGTTTTGTGATGAGAACAGGAAAGCCTACAAATTTAT
+
@@?DFDEFHHHHFGIHGHIIGEIHIJIGDHEHIHGGGGGGGHGEGDHGEIIHGBDFHIJJ=CHIJJHGIFIHHEHHBHFHFFFFFEDCEDDCCCCDCDDDE
@319
ACTTTATCCTGGAGCTGCTGCGGAAGGAGGAGTACCAGGGCGTCATTGCCTGGCAGGGGGACTACGGGGAATTCGTCATCAAAGACCCTGATGAGGGGGCC
+
<??;DBB,2ADDAEB;;EEFD<@FAEI>DDDD?BBDEIDD;A;A8@AEA@==A;C?@@?????>><;>>9?83><A88+>:A>33<><>9(::::>()5)5
@31A
CCAGTGCCTCGAGCGCTCAGGATGGAGGAAGACTCGATCCGCCTGCCTGCGCACCTGCGCTTGCAGCCAATTTACTGGAGCAGGGATGACGTAGCCCAGTG
+
CCCFFFFDDHAHDHIIIIJJIDFAHHGAHIJJJGICFEHIJIIGGFIGGEHEEBBDAAB@@?BDDCC??CDDC>DDDDCBDDDDBDDD@A<?ADDDDB<@A
@31B
CAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCC
+
CCCFFFFFHHHHHJIFJJJJJJJHHJJJJIIJIJJJJJJJIIJJIGJJJJJIHHHHHFFFFFFEEEEEEEDDDDDDACDDDDDDBDDDDDDDDDDDDDDDD
@31C
ACAGATGGAGGAAATGAAAACACGGCATAAGGGAGAAATGGAGAATGCTTTAAGGTCATATTCAAATATTACAGTTAATGAAGATCAGATAAAGTTAATG
+
;?@D;4BA+A?FHE<EAB?CFE:8@:8??GDDD3?)BGBBD?(9D@4=BB=F@CCFF7=7CE7C.)=7?A;@B?7)7;(;>;>;;;>@:@@AC@C5;5@@
@31D
CAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGG
+
<@;B?DDDHHFFFEDGGH@GGHGHIIIIEHDCGGG@C;?<DGDEHGGA9?9BFBFFGGIIEGIBG@=(==AEH@BDDCC;>AC?C;CA59CCBB5<>?CCB
@31E
CTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGC
+
CCCFFFFFHHHHHJJIJJJJJJJJJJJJJJJJJIJIJJIJJJIJIJJJJJJJJJJJJJJJJGIJJHHGHFFFEFFEEEDCEEDDDDDD@DDDCDDDDDDD
@31F
GTGGAGACTCATTTTGTTAACTATTCAGAGACCTTCTCCCTTTATTCCAGCTGTCTAACTGACAAGACCTTTCTCTCTTTCTTTCTGCCTCATGCTCTCTC
+
+:?DDFFFHGHGHJIGIJIJIIJFIGJGJIIIGHIIJJJJIJJJJJEIIJIJHGHIJJIGIGGII>FHHIGJIJIEDGEECHHGFFDFFEE;>CEEEDDDC
@31G
AGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACC
+
CCCFFFFFHHHHHJIJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJGHHFFFFFECEEEEEDDDDDDDDDDDDDDDBCDDDDDDDDDDEDDDDDD
@31H
ATATCAGATCCGAACTACACCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATGACATCTCCTGTGACTCTCACCTCTCAGACAACTAAGACAGATGACC
+
@CCFFDFFGHHGFHHIIIIGHGJJJIHIGHEGDFIJJJIGGEGIJJJIIIDFGGEHCIIGGHGHEHIGHIJDHCHGHF@DEEECACC@CCAC@CCDDDADD
@31I
GCCAGGTGTCCGGAATGCCCAACGACCCAAGCCCCCTGCAAGTGGCTGTGAAGACGCTGCCTGAAGTGTGCTCTGAACAGGACGAACTGGATTTCCTCATG
+
<?@FFF?DCFFHHGIGHIEHHIEGIHIHDB?GHIIJJJGIJJGADHEECCC?;ACB<?39>C;=A>>CA@CC>:ACCD@CDBDDBB<ACCDCCD>@>CCCD
@31J
AATAAATTGTCGAAAATACCTTCAACACCCAAATTAATACCAAAAGTTACCAAAACTGCAGACAAGCATAAAGATGTCATCATCAACCAAGAAGGAGAAT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJGIJJJJJJJGJJIIGIIJJJJHHHHHFFFFDDFEEEEDEEDDDDDDDDDDDDDD
@31K
CAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTT
+
@@CDDFFFHHHFHIGIJJIIJJJJJJIJJJJJJJGIIGIJJIIJJIJJJIIIIIFFHIIIIIHEHHHHFFFCEEEEDDCDDDDDDBDBBDCDDDDDDDDCD
@31L
TAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACC
+
@@?ADDDFHHHHFEIGIIHIHIJJIIGIIHGIJIIJIJJIDGIHIGIJJJGGIJGGIJJJIIEIGHEEHHEBCDDDDDDDDDEDEEFEEDBBDDDBDDDDD
@31M
GGAAGAAGGCATTTGCAGCTCCAGACTCAATTAGAACAGCTCCAAGAAGAAACATTCAGACTAGAAGCAGCCAAAGATGATTATCGAATACGTTGTGA
+
CCCFFFFFHHHHHJJJJJJHJJJJIJJJJJJIJJJJJJJJIJJJJJIJJJJIJJJJJJJJJJJIJIIJJJJJHHHHDEFFFFFEEDDECDDDCCBDDD
@31N
CGGGACTCGAGTGATGATTGGGAGATTCCTGATGGGCAGATTACAGTGGGACAAAGAATTGGATCTGGATCATTTGGAACAGTCTACAAGGGAAAGTGGC
+
@@@D?@BDDFFHBBEEBHBDHE8AFBFEHEGDEHII@HGCGGIIEGHEHHB;CGDEHICHHDIIC;CEAEHDCDE>DAA;@;>@;;>@CCDB9?AA@@AB
@31O
GAGGACAAGTGCAAGCCTATGTCCTATGAGGAGAAGCGGCAGCTCAGCTTGGACATCAACAAGCTCCCCGGCGAGAAGCTGGGCCGCGTGGTGCACATCAT
+
??@DDDFFFFHHHGGHGHIHIIJGHGGIFGIIBFG;@DHBHGDDEGDCHIBFFHIIIJHGHEFFBDFA<>@B?B<B@CDDDD@BD>BB59<BBADDDDACC
@31P
GAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACT
+
CCCFFFDFHHHHHJJJJIJJJJIJJJJI@HGIIJIIJBGHEIIIFJJJJJJJJJJJIIHIIJHHHHHHEFFFFECECEDDDDDDBDDDDDBBDDDDDDDB
@31Q
ACGGGAATGCGGGGAGATGATCGCTCCGACAGCAGGACCGGGTGGAGTGCAGCTGGGAGTAGGAAGCTAGCGTTTGGTACGGGGCAGAGCTTGGAATGCGC
+
0((2(((())((08(((0..))(0(('5''''.)..(((',3','((((+2(((((+(+(((++(((+86())(&(((++&&)&)&&((+(+++((((+&&
@31R
GCTGTATGTTTGAAAAGGGCCCCAGGCAGTTTTATGATGACACCTGTGTTGTCCCAGAAAAATTCGATGGAGACATCAAACAAGAGCCAGGAATGTATCGG
+
CCCFDFFFHFFHHJJJHIIIIIJJIIIIHCGIIIJIJGEIJJJJJJIJIIIIJJIJIJJJJJJJJJHHHGHFFFEFDCEEDDDDCDDDCDDBDCDCDDEDD
@31S
GTTGGTGTCAGCCAGGAGGGTCCTCCAGGCCTTCCGCCTCAGCCTCCACCACCAGTTGCTCAACTGGTCCCCATTGTGCCCCTGGAAAAAGCTTGGCCAGG
+
?=@D7ADDHHFH+ACGEF?@FEGGHIEH3?;BGCFAHGGGIGGG@BA>FFACCHG=C>EHECDE@@D3>ACCCC@>5;@CCB@BBAACCB9A>C?BACA<2
@31T
CAAGGATATGCACAGACCACCCAGCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGC
+
CCCFFFFFGHGDHIJJJJJJIJJJJIEGJJJJIJIIIJJJIGIAGCHGGIGGIJGGIJGIJIGGHHHHFDDFFDDEEEEDCDDDDDDBBDDDDDDDDBDDD
@31U
GCTGGCCCGCTCATTGCCAAAAATTCACCGCAGTGCATCAGAACCCTCCTTGAATCGGGCTGGTTTCCAAACAGAGGATTTTAGTCTATATGCTTGTGCTT
+
CCCFFFFFHHHHGJJGJJJJIJJJJJJJJJJJJIEHJJJJIIJJJJJJIJIJJJJHHHFFDDDACDDDEDDDDCDDDDDDDDDDCDEDDEEEDEECDDDDD
@31V
CCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGC
+
@@@BBADDHDHFDIJEGEHGHJEEEF?BBGGIJJIIGDFGHHB@HGIJDHCHE@CDC@F@CFGHCHIHHGFHFDFEF@BCCB:;@?AAC@CCDDC>@B
@31W
AAGCTGGGCCGCGTGGTGCACATCATCCAGTCACGGGAGCCCTCCCTGAAGAATTCCAACCCCGACGAGATTGAAATCGACTTTGAGACCCTGAAGCCGTC
+
1=8B=D:B;DDAF@FF)C?CEGEEBDA@GD0?BD?FEB@@EDFFFE?B;?7@AAACABCA;;;@/35;8@?@@:AA>@8@<BB@4@B8@@B@B@BBBB<05
@31X
CTGGGGCTCTCCCAAATGCTCCACATTGCCAGTCAGATCGCCTCGGGTATGGTGTACCTGGCCTCCCAGCACTTTGTGCACCGAGACCTGGCCACCAGGA
+
;@@DDAADBDFHFE@EEFFHGH>BHEHGEHGIF@F>DHIG6@DFHHI=:CGHCD@CGAGG@AAHEEFBB;@6>AAECCACCCCCC?=?>?B?AC<AAB@8
@31Y
CTCTTCTGGATGACCCTTCAAATTCTCATTTTATTGCCTGGACTGGTCGAGGCATGGAATTTAAACTGATTGAGCCTGAAGAGGTGGCCCGACGTTGGGGC
+
CCCFFFFFHHHHHJJJJJJIJJJJJJJJJJJJJJJJJJJJJIJJJJHJJIIJJJJJJHJJJJJJJJJHHHHEHFFFEFEDEEEDCBDDDDDDDDBBDDDDB
@31Z
CTTTCCCCTCGCTCCTTGAAGGTTACCCCTTGGGAAGGCTTGTGCCCCATGCCCCATTACAGGCTTACACCCAGTCTGATCAGGCGGAGTTTTTGATGTAT
+
;??A+=AB+)))<A@E4A<AE>2<<??E))?9?DD?;)09)700*0)(7=C37)(-7;)...=1;)777(.9;?;>55(-(5>>('))0((44+)8>>:>B
@320
CTTTAAAGCAAGAGAAAGAACAAGTTTCATTGAGATGTAGAGAGCTAGAAATCATTATTAACCACAACAGGGCAGAAAATGTACAGTCATGTGATACTCA
+
C@@FFFFFFHHHHJJJIIIIJGJIEHIIJJJGIICEGFIIIGHHIJJIFIIGIIIGIIIIIJJIIIJHGGIIJHGGFFFDDFEEEEBCCE@>ADCFDDDC
@321
GACGGTTTCGCCGGCAGTCTCGATGATAGTATTTCTGCTGCAAGTACTTCTGATGTTCAAGATCG
+
@@@DFFFFHHGHFIAGHHIGIGEIGGGFEBFFGIADGIIIFIJJ=CEGHGGGGIJIIJGFEHFHB
@322
CCTCAATCTTGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGGACCTGGGAGCTACCCCATGCAGCCAGT
+
-0-8@@?=8).)298;11//(1:13)97=3==91(3=)=)3)66=1)6)8330=3>;8.37==;==8===((9',5;02;<0(0:(228<66872:<<75+
@323
CAGACTAGCAGCGGACAGTACATTGCCATTGCCCCAAATGGAGCCTTACAGTTGGCAAGTCCAGGCACAGATGGAGTACAGGGACTTCAGACATTAACCAT
+
CCCFFFFFHGFHHIJGIJGGIJIGGGJJJJJJJJJJIIJGHIFHIJJJIIJHJJGIJJJHHHHGHFFFFFCEEEEDCDDDEDDDDDDDDDCCBDDDDDDDD
@324
AAAGAATTGGATCTGGATCATTTGGAACAGTCTACAAGGGAAAGTGGCATGGTGATGTGGCAGTGAAAATGTTGAATGTGACAGCACCTACACCTCAGC
+
CCCFFFFFGGHHHJJJJJJJJJJJJIJIJJIJJJJJJJJIIJIJGHJJJJJJDHHGGFHIIJJDAGHIIGGEHHHHHFCHFFFFDCBDCACC?CC?@CC
@325
CAGAAAACCAAGTCATACCAGTGCTGTCTCAATTGCAGGAAAAGAAACTCTTTCATCTGCTGCTAAAAGTGGTACAGAAAAAAAGAAAGAAAAACCACA
+
CCCFFFFFHHHHFIJIIJJJJIIIJJIIIJJJJJIJJJJJJJIJJJJJJJJIJJJJJJJJJJJJJJJII=DHCHGIHFHHHFDDDDDDDDDDDDDDDDD
@326
CAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCT
+
@@@FFFFAHHHHHFIGEHIGEHGEEGCH?BG9D9CBFHBH9BB:<DG;B=FGIIDG)@GH;GCCEHF=7;@CEA;C>C@>;>@ACDC(8955>A98A<<C
@327
CTTCCACCCACATGCCAAGGCAATCTCCTTATCATGGGGACTGAGGATGCCTCCTCCTTGCCTGAAGCCAGTCAAGAGGCAGGGAGCAGAGGCAATTCCTT
+
@@CFDFDDFFFDHBDHHGGIIBHGGHIIGIIIEHGHCHCHGGEFHGAHCDHCEDEHIGIIDD=7@ECEEEDDFCF>CCDBD???<28<?<?BBBBC>4>@C
@328
GTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACC
+
@@@BADDADDHFFGGGBGIEHICHHHIIIIIICEEHIBBFHIIEGBB9;DGBBGGEFGFHIGCHGHEHEADFDEBECA;AACC@ACCCDDDDDA>ABDDDB
@329
TGACCCTGGAGGAGGGACTGCCATTGGCTGTGCAGGAGTGGGAGCACACCAGCAACTTTGACCGGATGATCTTTTATGAGATGGCAGAAAGGTTCATGG
+
??8DDDD>?2A?;A1?6A8CFGG<?C<C?8):?F?A;?)??D(-@B(=2@6=97=6AEEFEDD<=938;5;35>A>>>>,5:@>?BB09:A8(+>(>>A
@32A
GAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACC
+
C@CFFFFFHHHHGIJIIJJJJJJJIJHJJJJJGIIJIIIJJJIJJGIIJIJIGHHFFFFFCEEEEEEDDDBDDDDBBDBBDDDDCDDD@CCCCDDDCDDD
@32B
GGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTTCAAGTCAATATAGCCAACAGAGCAGC
+
=81ABDDDF?3DDF@E4<:CFGC:FCEEF@9CG9DFF?FDFIC@GFFFI@(=C@;@E.@E4@>E;=?>B?566(;@B-5@B;;@;3:@@B@BBB53A<B
@32C
GGAAACCATAGAACCTGTCAACATACTAGATGTTAAAGATGACTGTGGCCTCCAACTAAGGGTCAGCGAGGACACCTGCCCACTGAATGTTCATTCTTA
+
CCCFFFFFHHHHHJJJIHJJJIJJJJJJJJJJ@GHIJJIHJJJJJHIIJJJJIIJIIGIJJJEHIIIIFHGFFFEDCEEDDDDBDDDCCCCDEEEEEED
@32D
TCCAACTAAGGGGCAGCGAGGACACCTGCCCACTGAATGTTCATTCTTATGACCCCCAAGGAGAAGGCAGGGGGGATCCTGATCTGTCCAAGCCTAAAAAC
+
-;((<).)=4.@(@?8;3(-((:).0).((9=61)<.7>8)/3)8=1>9863.).;5=/=;(97((.,,99;'))5&+(++(+(5(52((+828(8(8(2&
@32E
CGGGAAGATCAGAAGCCAGTCATGGATGACCAGCGCGACCTTATCTCCAACAATGAGCAACTGCCCATGCTGGGCCGGCGCCCTGGGGCCCCGGAGAGCA
+
@@CFDFFFHHHHGJHGIJJ@GIGHJG@GIIJJJJIJIAHGIIICGGHGIJJHHHFHHBEFFFEEEDEDDCDDDBDDDD@DBDDDDDDDDDDDDDBBDDDD
@32F
CCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGT
+
CCCFFFFFGGHHHJIJJJJJEGHIJJIIJJJJJIJGJJJJIIJJIIJIJJJIHHFHHHFFFFFFDEEEEDDDDDDDDDDDDBDDDDDDDDDDDDDDDDDD@
@32G
CTGGAGTTTGTCACCAGTGGAGGCCGGATGGACCCACCCAAGAACTGCCCTGGGCCTGTATACCGGATAATGACTCAGTGCTGGCAACATCAGCCTGA
+
@@@A?ABDBHFHABDFFHGIGCGFBGIIEGGCABBB@@DDC=CF=@@FFA>@CA;65?77;??CAA>3;@>>5@@@:A5@C>@C?9>AA9ACDDDCBC
@32H
AACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGG
+
+??DDBDDD+C2AE@3ACFAAEIAEDCDDIC>@;DD;8DBDD?DDD=CBBB@DDD@C=@@ADCDACA;?DA@A==???=>?AAAAA>AAA?>>?><><AAA
@32I
GAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGAC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJHHHHFFFFEEEEEEDDDDDDDDDDDDDDDDDDDDDDDDDDDDDEDDDCD
@32J
CGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCG
+
@@@DDDD<FHDD?GGIG@8C:CAEHIDG?H6?BFGA<BA0AEGGAE>:9B;BCCDD3;@A;ACCCCCB<@CCCC@5&599A@29?<??@:(:ADCA>>>A&
@32K
CTCAGGTGGAGTCATGCTTATATGGAGCAAAACTACTGTAGAGCCCACACCTGGGAAAGGACCTAAAGGTGTATATCAAATCAGCAAACAAATCAAAGCTC
+
CCCFFFEFHHHHHIJJJJJJJJJJIIJIIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJHHCECEDFFFFFFEEEEEEDDBDDDDDDDDDDDD
@32L
GTGAAACTCTGAGAAACAGCACTCATAGTAGCACAGCTGCAGACTTACTACAAGCCAAACAACAGATCCTCACTCATCAACAGCAGCTTGAAGAACAAGAC
+
?@<DDEDEBDFAHBHHIGGIGIIIGHAEE@9<GAFBDDGGHHDHAEIG>>*B?986BCEH8;=FFIGI@EHHAEH;CDDC@C>B@@6>@??A@@C?:?9AC
@32M
CGGGAGCCCTCCCTGAAGAATTCCAACCCCGACGAGATTGAAATCGACTTTGAGACCCTGAAGCCGTCCACACTGCGTGAGCTGGAGCGCTATGTCACCTC
+
@@CFFFFFHHHHHJJJJJJJJJJJJJJJJJIJJHIIHIIIJIJJJJJIHHHHFFFFDDECEDDDDDDDDBCDDDDCBBBDDCCDDBBCBDDDDDEEEDCCB
@32N
GCGTAGAGTCGCTGGAGCGGGCGGAGCTGTGCGAGAGCCTCCTCACTTGGATCCAGACATTTAATGTGGATGCACCATGCCAGACCGTGGAAGATTTAACG
+
?784=0+=,<:@DEEI<AFEA@@ADA@6;;AA@?>??(9>55==A?A3>3>A>=AAA2<A>B:AAABAA34><>AA>>:>AAA?<<55<>7>>>A>AAD><
@32O
CAGGAGCTGCAAGCCATGCAGATGGAGCTGCAGAGCCCTGAGTACAAGCTGAGCAAGCTCCGCACCTCGACCATCATGACCGACTACAACCCCAACTACTG
+
@@@D=BDDADHBH;?@FBGCHABHBECFC?C9CC?*)::BGG?BGG*??DGEFEEHGDCHII;@:BBBBB>9;C>@;AC>@?=9>>AC@:<59@8??@>C:
@32P
GCCGGCAGTCTCGATGATAGTATTTCTGCTGCAAGTACTTCTGATGTTCAAGATCGCCTGTCAGCTCTTGAGTCACGAGTTCAGCAACAAGAAGATGAAAT
+
?<<BD?DDDDD<?@CEA?FEF4CFIE>D<E*???B?D?DD<BDDBBDDDEDEED4?B@ACCCCEDC;CCC?7=C>??19=;;>A>>>>=;35<:3>>AA>A
@32Q
GTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGC
+
CCCFFFFFHFHFHJJIJJJJJJJJGEIIIIJIJIJJIJJJHIIIHJIEHHIIIIJIIJJJJJHHFHFDFFFECEEEACEDEDCDDDCDD?BDDDCDDDDDD
@32R
CGCTCATTGCCAAAAATTCACCGCAGTGCATCAGAACCCTCCTTGAATCGGGCTGGTTTCCAAACAGAGGATTTTAGTCTATATGCTTGTGCTTCTCCAA
+
CCCFFFFFHHHHGIJJJJIIJJJJJJHHIIJJJJJJIIIJJJJJJIJJIJJJJJGIEHHGGHFFFFFEEDCDDDDDDCCDDEEEEDEEDBCCDDCCDDDD
@32S
TCACACTTTGTCAGATGAGAAATGGGATGTTATTAACTGGAGGAGGGAAAGACAGAAAAATAATTCTGTGGGATCATGATCTGAATCCTGAAAGAGAAAT
+
CCCFFFFFHHHGHJIJJJIIJJJJIJJJJIJJJJJJIJJJGIJGIIJHIJJJJJJJJJJJJJJIJIJJHGHHFFFFFDEEEEEEDDDDDDDDDDDDCDDD
@32T
CTTCTGAAGAAATAAAACAGTTAATGGGGACAGTCGAAGAACTTCAGAAGAGAAATCATAAAGACAGCCAGTTCGAAACTGATATAGTACAACGAATGGA
+
CCCFFFFFHHHHHJJJJJIJIIJIJJJJJJJJJJIJJJIJJJJJJJJIJJJIJJJJJJJJJJIJJJJIHHHHHFFFFDDEEDCDEECDDDDDDDDDDDDD
@32U
CGGATGGAAGGCCTCTACAACCCCACGTCAGAGTGTGGGATTCTGTTACTCTATCCACACTGCAGATTATTGGACTTGGCACTTTTGAGCGTGG
+
+=;7==1+7<++2<2?@BBAB77<1@?:5:A*000*08829>37=8)>A78.8=ABBAB7A7AAA3A>@9?@:)(635;>?;5;;;=88====;
@32V
GTCACCACAACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACA
+
???DDDDD3CDBDE3AEECFEEFIIICEEBDEDB?9?DDEEDADDDDDDDCCDDBDEII;CAE=;CADDCDDDDDDAAA@?????????AAAAAAAAAA
@32W
CCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCAC
+
@@@DFDDED>DFBHACFHICBGCHGGHGGE=F):DHG@8)?D;BF?9?3B@8=FBHGGG;4=@@GA=EE;=DDACC.>C@@CC>>@CCCB<<<B:A>CAAB
@32X
GCAAAAGGAGCAGAAATAAAGACAACAAATGAAGTTGTTTTGGCTGTGGAGTTTCACCCAACAGATGCAAATACCATAATTACATGCGGTAAATCTCATAT
+
@@@BDFFDAFFHH;CEFF>C>@FGIIDHDEHIEHIEHDGGE@DGHIFHIGAFFGH@GFGC2@AG@CEHFEHDFBDDFCEEDECCA3;>83;@C3>>@>ACE
@32Y
CTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGC
+
@CCDFFDDFFHHHIJIIGIJJIIJIIJECHJGJJJIJJGFIIJIJGGJIGGJJIFHJJJIGIJIJIIFFEFHFDDFCCEEDDBDBBDDDDDDCCCDDDDDD
@32Z
GGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACAC
+
CCCFFFFFFHHHHJJJJJJJJJJJJJJJGHIJJJJJGIIIIJJJJJIJJJJJJJJJJIJJJJJJJJJJHHHHHFFFFFDDEEDDDDDDDDDEEDDDDDDD
@330
TGGTTATCGAGGAAAGGACTGTAGAGCTAATGTTTACCTTCTTCCGACCGGGGAAATAGTTTATTTCATTGCATCAGTAGTAGTACTATTTAATTATGAGG
+
@CCDFFFFHHGHHJJIJIJJJHIIIJJJJJJJIJJJJJJJJJJJJJJJJJJJHFFFDEECFEEDDEFEEEDDDEDDDDEDFEEEEEEEEEEEEDEEEDDDD
@331
CTAAACTGGACATATGGTTATTGCGGAAAGGCCTGAAGGGGTAATTTTTTCCTTCTTCCGACCGGGGGAATAGTTTATTTAAGTGTATCAGTAGCAG
+
;3-(()).)):)))264)98))))(2((-=(((:9);6)((0()/))9<'833;:).6>''',93'3&)&(((3::(58((((+++(+((6(26((+
@332
CCAACGGCGAGGATCACTTCAGCTCTGGCAGTTTTTGGTAGCTCTTCTGGATGACCCTTCAAATTCTCATTTTATTGCCTGGACTGGTCGAGGCATGGAAT
+
>><1A<=0)0):):?51?07=A=B<0=>AA<9//=5A66=.))77==A;))).;;;>>5.;(>@=>B;>;>?3>>?359(55(,9;88:0&5;&(+2+833
@333
GTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGC
+
CCCFFFFFHHHHHJIJJJJJIJIJJIJJJJJJJJJJJJIJJJJJJJJIJIIIJJJJJJIJIJIHHHG>CDFFFFEECEEEEDDDACDDDDDDDDDCDDD
@334
CCCGAAGCCATACAGCCCCCGGCAGGAGAGCACACGCGTGATCCAGCTGATGCCCAGCCCCATCATGCACCCTCTGATCCTGAACCCCCGGCACTCCGTGG
+
@@@;B@@?FHD3AE?EHGGBHFIDFF<18((==BFGG8E<BD>DA;;..6;ACC=A@BBBB1,9::(4:CC?@BC@3(:@>>4@CBBBB3009B<>?B?<<
@335
GACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACAC
+
CCCFFFFFHHHHGIJJJJJJJJJJJIIEHIJJIJJEHHIGIJJIJJIIJIJJDIHG@FFGICFGIIIAHHHAHFFFFFDCCEBDCDDDDDDEDCCDDDD
@336
ACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCCTGGGTGT
+
1;?DDDB?><BDFBB3C2<?FAGEE92ABEGIEDEFF<FG;?@DGC;))0??B*<FFF@EEEA>EA);@B3;7;8'93=<@BB?@BBB8(:4>((2?@350
@337
GCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATAC
+
CC@FFFFFHHGAHGJJIIJJIJJJIGIJGIJIGIGGIGIJIIJGGIJJGGIJJIJIHCHHF@DCEEEEEEEDDDDCDC>CDDDBBDDDDCDDD@ACCCCDD
@338
CGGATTCTTTTTTCACCATTCTTCCACCCTGGAAACTCTATACACACACAGCCGGAGGTCATACTGCATCAGAACCATGAAGAAGATAACTGTGTCCAG
+
@@;DBDDFBHHGDGFDHGHIIEHHIIIIEIHIIIIIFGHHCHGGCCHGEAGHIIGBEB?C@CBBEEE@CEDDDCCBB@CD@>CDDDCCCD@AACCCDDD
@339
TCAGAACCCTCCTTGAATCGGGCTGGTTTCCAAACAGAGGATTTTAGTCTATATGCTTGTGCTTCTCCAAAAACACCCATCCAGGCAGGGGGATATGGTGC
+
CCCFFFFFHHHHHJJJJJJJJJJJIJFHJJJJJJJJJIJJHIIIJJJJJJJJJJJIJJIGGJJJJFHHHHHFFFDDDDDDDDDDDDDDDDDDBBDDDDACC
@33A
AAAACACTTGGTAGACGGGACTCGAGTGATGATTGGGAGATTCCTGATGGGCAGATTACAGTGGGACAAAGAATTGGATCTGGATCATTTGGAACAGTCT
+
CCCFFDFDGFDCFHBHIHIGICHCIIIAGII@ECHIIIIHIIGIIIIIAHGIGGGIIGIHE4CEEHHEBC@CCCACA@CDDD@>@>9C@@;@>C>ACDCD
@33B
GCAGAGTCCTTCCAAGAAGCAGAAAAAAAAGAGAAAAACGTCAAGCAGTAAACATGATGTGTCAGCACACCATGATTTGAATATTGATCAATCACAGTGT
+
CCCFFFDAFHHFHHFHIJG:FHEEGHIBIEHCGGHIIIIGGHGGICGIHGIFHFHHFECC>7;>>>CEC??ADDC@CDD@CCEECCAD@CC3::CCCCCA
@33C
CTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCT
+
@@@FFFDFHHFDDHAGEGGGIGCHEEIGGGGIIHHAEGIGGIDDEHIHIECGIEE@FHGHIJ@HHF@@;;AACEDDDD@DCDDDA@BDDBDBDDCDDACD>
@33D
AGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTAC
+
CCCFDDDEFFFHGGBGEGEGHJJIGIIIJFGICAHEHJJEHJIGGGIAFFHGGDDHH@EBDFACECC;@CCC@AACDDCCDCCDCC>A@>CCD?@@5<BD
@33E
GGCGAATTTGGAAAAGTGGTCAAGGCAACGGCCTTCCATCTGAAAGGCAGAGCAGGGTACACCACGGTGGCCGTGAAGATGCTGAAAGAGAACGCCTCCCC
+
@@@DADDDHFFAFFGE?FHAHBCGBFEBGFIIIIIIIFGGGHCDFEGGH-;6C=@C<7=A>??BDEC=A@B;;2;BBA>@AC@CCCA>?CCCC-<5(5?B@
@33F
GCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACC
+
;=?DDD?DFFFDH<FBGGIGIGACFHIGAH@FGIIIEDDHIIGEHGIGHI@GEHGGCHGIIICEDEEECBD;@CCCCBCCCCCCCDCCCA?@??BCAC:?
@33G
GGTTACCTATGGGACTGAAGGACTGCAGCAGTTACAAGAATTTGAAGCTGCCATTAAACAAAGAGATGGCATTATAACCCAGCTCACTGCTAATTTACAAC
+
B@BDFFFFHHHHHJGIIJJJJIIJIJJJJIIJJIIICIJJJJIEGGIIHIGHIJJIGHHGIGGFHHGGIGGIHHEHHEFFFFE>CCEDCCDCDCEEDDDD:
@33H
TTCAAACATCAACAACAGGGACCAGATAATTTTTATGGTGGGACGAGGATACCTGTCTCCAGATCTCAGTAAGGTACGGAGTAACTGTCCAAAAGCCATG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJIDHIJIIJJJJJGIJJJJJHHHHHHFFFFFFFDEEEE>CDDDDD??CDDDDDDDDDDCBDDDD
@33I
ACTCGATCCGCCTGCCTGCGCACCTGCGCTTGCAGCCAATTTACTGGAGCAGGGATGACGTAGCCCAGTGGCTCAAGTGGGCTGAAAATGAGTTTTCTTT
+
?@;DDDDDDHFFFGI3A<E?@FHIIGDBHB:@8BEG;FGIIIGGEEG7CGG<CEEB?C@A5;;?C?@BC>?<9:ACC;@C@B?BBCC@A@CCCCCCCCCC
@33J
AAATCTTTAAAGCAAGAGAAAGAACAAGTTTCATTGAGATGTAGAGAGCTAGAAATCATTATTAACCACAACAGGGCAGAAAATGTACAATCATGTGATAC
+
;;1B::BBDF><:;3?@3+<CE?AEE@FHF9?C?B?E9:D*?**090?)9?39?DF:<?@BFD<=C>.5@;56CE((5'();@3;.(6(((-(55>(-;(5
@33K
AAAAAAGAAAAGCACAAAAGGAAAGAGGAAGTGGAAGAGAATAAAAAAAGCAAAGCCAAGGAACCTCCTCCTAAAAAGACGAAGAAAAATAATAGCAGCA
+
@C@FFFFFGHHHGJJJJJJJJIJJJHIJHIIHGIIJJHIIJIJJJJJJJHHHHFCDFFFDDEEDDDDDDDDDDDDDDDDDDDDBDCDDDDDDEE>CCABB
@33L
GCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGT
+
@@;ADD;BDFFFFBIFF9CA8FAAF<EFFAFFFDFFA@GIFIF>GGIEFIBFIBFF3BCA;F@EF9=;A;>89?8??>ABB@@:38<?<B?@@>A:3:AB(
@33M
GAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACC
+
@@@DFFFFGHHHGJJJJIJJJJJGIIJJJIJIDIJJJJIJJJJJJIIJIIJJHHHFFFFF@CCEEECDDDDDDDDDDDBDDDDDDDDDDCDDDEDDDDDD
@33N
CAAAAGCCCACTGACGCTCCACCGAAAGATGATTTTTGGATACCAGAAACAAGTTTCATACTTACTATTATAGTTGGAATATTTCTGGTTGTTACAATCCC
+
CCCFFFFFHHHHHJIJJIGIIGIJIJJJJJJHGHIJIJJJGIEHJJJJJIJJGIIJJGHHGHHHFFFFFFF>CCDEEEACCDFE>CDDCCDDBDDDDDCDD
@33O
CTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCC
+
@@@FFFDFFHHHHJJJIIJIIBGHJJIIJJJIIGHIEHGJIDGGGGIHIGIJJJIHHIIHEHHFFFFFFBCCECDDDDBBBBBCCDDCCDDBBDDDDDD
@33P
CTCCCTCCATCGCAGTCCATACCAGATAGCAGCTACCCCATGGACCACAGATTTCGCCGCCAGCTTTCTGAACCCTGTAACTCCTTTCCTCCTTTGCCGAC
+
@<<DFFFFHFHDDGDCFD@HFHDGHEHDCGEDEFHBHEHGCHIBGHBGBB>GCCHEIGBHBECCECC>CACCCCCACCCACCCACC@AC::?CCCACCBBC
@33Q
AGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAAC
+
BC@FFFFFHGGHHJJIIIJJJJJJGIJIJJJFIJJJJIJJJJIIJJJJIIJJDHIJIHIJJIIJIHHGHHHFFFFFFCCEEEEDDDDDACDDDDDDDDDDD
@33R
CTGAGACTCCTGCTCAGTGTAGCATTAAGCAGGAACGAATTTCATATACACCTCCAGAGAGCCCAGTGCCGAGTTACGCTTCCTCGACGCCACTTCATGTT
+
CCCFFFFFHHHHHJJJJIIIIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJIJJJJJIJJJJIJIHHHFFDEEDDDDDDDDDDDDDDDDDDDDEDDE
@33S
CTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTT
+
?@;DDDEDHHHHHIGGGEDHFHGIIIGHIIII9?FGAFHEGIIHHIIIIHIHIGIIIIEIIIII<EEF>CCCEDA?CDDDD>CCCAA<<BC?BDDA?CD4:
@33T
GAAAAGTGCCTGTACAATGTCAGTGCCTATGATCAGAAGCCACAAGTGGGAATGAGGCCCTCCAACCCCCCCACACCATCCAGCACGCCAGTGTCCCCACT
+
@C@BFDFFHGDHCGGEGGIFHIGACHHIIGHHIIIDHGGIIJG@BGBDEGCCBEF@CGHGEHHCGGGGGHB@@BDDBDCDDC>9?B-<?BDAC>ACCDDD8
@33U
ATCATGGTCTCTGTCTCCCCGCCTGAAGAGCACGCCATGCCCATTGGGAGAATAGCAGACTGTAGACTGCTTTGGGATTACGTCTATCAGTTGCTTTCTG
+
CCCFFFFDHFFHHJJIJJJJGIIIIJJJFIJGIJJJJJJJJIIIJJIJFGIIJGIIJJHEHFEHFFFFFFEEEEEDDDDDCD?BDBDDCDEEDDCDDCCD
@33V
TGAGGAGGAGCGAGCCCAGCGGCTGGCTGAGCTCCAGGAGCAGCTCAAAGCCGTGCACGAGCAGCTTGCAGCCCTCTCTCAGCCCCAGCAGAACAAACCA
+
=??:?B?AFABFDAFG?C?F?CF@GGI9B2BF77@@FEE=GBHFHEDEBBCAACB>@C?8=????>CCBC3>@?<?(934>:@?@B8?@9239CCCBBBB
@33W
GCCAGCCTGTCCAGGGGTATGGCACTGGGGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACT
+
=<7AA1<=?+<ABB>A617=A32+::?@))?:;?=?B<A<09<;=BA<).=>>7.).8>7;5==A@@9((,(.,;?5;3-;9(553;((,533833;73:3
@33X
CTGAAGACAGACATGGAACGTCACATCAACGAGGAGGACACAGTGCCTCTTTCTCACTTTGATGAGAGCATGGCCTACATGCCGGAAGGGGGCTGCTGCA
+
CCCFFFFFHHHHHJJJJJJIJJJJJJJJJJJJJJJJJHIJJJJIIIJJJJJJJIJJJJJJJJJHHHHHFFFFFEEEEEDDDDDDDDDDDDDDDDDDDDDD
@33Y
GCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGT
+
@C@FFFFFHGGGHJJJJJJJIJJHJCHGIJJJJIJIIJEGGGGGECGIIHIIIJIGIGIIGHIEHIIJHHHFFDDDEEDCDDCCCDCACBDDDDDDDDDA:
@33Z
AGCAGCGATAGCTCCTCGGACAGTGACAGTTCGACTGATGACTCTGAGGAGGAGCGAGCCCAGCGGCTGGCTGAGCTCCAGGAGCAGCTCAAAGCCGTGC
+
CCCFFDFFBHHFFGIIGGGDIEGBFHGGIHIIGGHEHGHEIGGDGH@CGI;A;1@EEBEDCABA@@B=>@<CBBBCDAC::A+8AB?<?CCCC><<<B9<
@340
CTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJIJJGIIIIIJJJJJJJIJJJJJJJJJJIHJHHHHHHFFFFDDDDDDDDDDDDDDDDDDDDDDD>
@341
GGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTAC
+
@@@DDFFFDDFAHIIIGIIIIHIHIJJIHFFHFGGIGIGGGGGIJJDGDGIGGIJGGIGHEAACEDCFFCCEEECDDDDDCDDDDBDBDCDDCDDDDCC
@342
CGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCA
+
@@@DFADDDDFHHIGHGHIJJIIIIEIIIJJJIDHIJIJJJIIIJIJIGIJJIJJHFEHFFDDDDDDDDDDDDDDCCDEDDDDCDDDDDDD?BBBDDDD
@343
TGAGAGAACGAGGTGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCC
+
=1+2?A=>=A8=))2<2+++<21):*1?A=>5:8=<A>AA04:>A>>BB=>B;>A>7=;>@=(6;>>>6'3',99:0811+(3+3=???????5;5;3(28
@344
CAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTAC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJIJIJJJJIJJJJJJJJJJJJJJJIJJJJHHFBDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDACDDEDD
@345
CAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTCCTCCCCTTGGAGGGGCACAAACGATCAGTA
+
?<@?DD>A;:AACAA:<ACAA<FB9AAA?:?BE<E<:99DGI6B?F?0B;?DBF;=8AB>8B@1?6)..7;76;?>@2?;(=BB6>B0?<BB9&(+&+>4
@346
GGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCC
+
@@=DDF?ACFDHHGGHEIII@GEEGGG?GIBDGIGEIDB=D>FHEGDEHFGBHECEA>@?C>7>ACCCE@CDCCCAA@BBDCCACDC>>4@AC<ABDDDD
@347
TACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGC
+
@?@FFFFFHHHDFFIIGIIDGIGHIIICBGHDIGIIDHIIFHFBHB>FDHIJ<GBFIJ>=@AFCH;CEHCHGFEF@DFEEE?CCCDC?A?=?BBDB@AB
@348
AGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJIJJJIJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJHGHFFFDCDDDCDDEDDDDDDDDDDDDDDDDD
@349
GAACACTCTGCCATCCCCCAGCAGCTGGGACCTGCAGCCAGAACTTGCAGCTCCACAGGGAACTCCGGGACCCTTGGGTGAGGAGAGGAGAGGGTCTGGG
+
@@@DD?DDHF8FAE?CEHFGGCCHB31?CEDEEIAFGEGGI9DB94DFGDGHG37=;@D7EAAH>E?<8/;?B?CCCAB=(+++8A2<AB2<892(9393
@34A
AAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGT
+
@@@DDBFDHHHHBHGIIIHGHGDGHIIFHIIIIII@DDAGHIIIIIIHBGGGGGGHIGIGHGGGHHFDEEFFDEECCD@DBDDDDDDDDDDDC>>:ACDD(
@34B
GGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCC
+
@CCFDDDFHHHHHGIJJIJJJJJJIJJJIIJGHIIJIHIJJIJJJJGIIIJJJJJJI=CFIGGGIHGGHGFFFFDEEECDDDDDCDDDDDDDDDDDDDDDD
@34C
AATTTTGGAAATTTCAAAGCTAAAAGATTTACAGCAGTCTCTTGTAAATTCAAAGTCAGAAGAAATGACTCTTCAAATCAATGAACTTCAAAAAGAAATTG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJHIIJIJIGHJJJJJJJJIHIJJJJJJJJJIIJJJJJJJJJJJJHHHHHHHFFFFFFDDDDDDDC
@34D
CGAGGACGGGCTGCATAGGGAAGGGAAGCCCATCAACCTCTCTCATCGGGAAGACCTGGCTTACATGAACCACATCATGGTCTCTGTCTCCCCGCCTGA
+
B@@DFFFFHGHHHIEIJJJIJJIJIIHEIIGIIJIIJJJJIJIIIGHEHEEHBEEEEEDECDDDDEDDCDDDDDDCDDDD@A>CCCDCDDDDD9@BDDD
@34E
ACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGT
+
CCCFFFFFHHHHHIJJIJJIJJJJJJHIJJJJJJJJJJJJJJJJJIIJJJJJJJJJJJJJJJHHHHHFFFFFFEDDDDDDDDDDDDDBDCDDDDEDDD9>>
@34F
GAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGAT
+
??<DDD??BD3<AAACA++<@@CEEID?:DA@?D<9B8BDED<8BBBCBDCADE>ADA><?A@>>>??>>A5:3;AA>>A>9>?>>><>?><<>AAAA?A
@34G
CCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATG
+
CCCFFFFFHGHHGJJJJIIJIIJJJJJIJJJJJJJJIJJJJJJJJJJJIJJJIIJIIJJJJJJHHGFFEFEEEEEEEEDDDDDDDBDDDDDDDDDDDDCDD
@34H
CTCAAACTGGAGTGGGCATATGGTTATCGAGGAAAGGACTGTAGAGCTAATGTTTACCTTCTTCCGACCGGGGAAATAGTTTATTTCATTGCATCAGTAGT
+
CCCFFFFFHHHHFHIJJJJJJJJHHIIJJJJJJJJJIHIJIGIJJIJJJIJJIJJJJJJJJJJJJJJHHFDDDDDDCDDCDDDDDEEEEEDDDEDDDEEDB
@34I
CTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAAATGGATCCT
+
???DB?8B?D+A<C@<ADBEEED<4?C?)1:D9:?BD*?D9D8B<@D@CC@=AD;>CACC=;=/?(.6;>@>?@==AA>:AA<:5,383(8<(+44>AA?>
@34J
AGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACC
+
CCCFFFFFHHHHHJIIJJJJJJJJJIJJJJJJIIJJJJIIJJJJJIIIIJJJGGHFFFFFEBCCDEEDDDD?BDDDDDDDAB<CCDDDDDDDDDEDDDDDD
@34K
GTTGTCCCAGAAAAATTCGATGGAGACATCAAACAAGAGCCAGGAATGTATCGGGAAGGACCCACATACCAACGGCGAGGATCACTTCAGCTCTGGCAGTT
+
=:?D:A:BDDHHFA@?:AAHEHB>BE@>CC>C?9FFFBAFHG>9D@DDHICDF;@4@@;;DHAHDE@?D@CCCBBB=B5959><9@4:43>>::(4@CB(:
@34L
CAGGTGTTCATTTATGTGTTATTGATGACTCCAATGAGCATATGCTTACTGTATGGGACTGGCAGAAGAAAGCAAAAGGAGCAGAAATAAAGACAACAAAT
+
@@@FADDDGDDHFGHIEFIHGIGGD<HHIIJIEHJJJGJJJIFIJJIJJJIHFGIIIGGGIJGJJIIIGIJJJJJJHGGHFBEFFEECEEEDDCDDDDDDD
@34M
CGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJGJJJJJJJJJJJJJJJJJHHHHHFFFFDEEDEEEDDDACCDDDDDCDDDDDDDDDD
@34N
CTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGATATACTTCGTTGGGTCGGGGAGAACAAAGAATGGTTTT
+
@@@ADEDDHHFFFHEHGA;@EDBDFEHGIFHIIAFHIIIIIGGIGGIIHGIIEGGGIIIIEHEHEA>?CCBBDCCCB=;?BBB@B>ACACBCCBCCC>ABB
@34O
GGAATTTAAACTGATTGAGCCTGAAGAGGTGGCCCGACGTTGGGGCATTCAGAAAAACAGGCCAGCTATGAACTATGATAAACTTAGCCGTTCACTCCGCT
+
@C@DFFFFFHDHHFHIIGGHGIE>GIID=AAFHEHJGAHIGHJJJJGIJJJJIHHHFBFFFABBDDDDCDCDCACCCCDDDDCDDCDCCDBD?ACDDCB>5
@34P
GTATTTCTGCTGCAAGTACTTCTGATGTTCAAGATCGCCTGTCAGCTCTTGAGTCACGAGTTCAGCAACAAGAAGATGAAATCACTGTGCTAAAGGCGGCT
+
C@CFFDFFFHHGHIJJGGHGJIJIJJJJIIJIJIGHHIJJIHIJIGGIJIJIJIIJJJJIJGGJJJJIIJJJHHHHHHFFFFFFCDECCCCDDDDCDDDDD
@34Q
GAGAACTCAGCGACACTACCTGGGCCATACAGACTGGGTGAAAAGCCTTGCTATACATCCTGACAAAATTAGGATTGCAACTGGACAGATAGCTGGCGTGG
+
?;;BD8B+C:+C:1EE3?AEBEE=EDB9319??0??)00.8?D*8(8=;@9=CCCAC)).77=)7AA?A));(6>66(;>;;5>A9:1:5>A:>>?7;&&)
@34R
GGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATAC
+
CCCFFFFFHHHHGJJJIIJJJJJIGGJJJJJIGIJJJJJJJIJIJJJIIGFGIIJIJIJJJHHFFFFDEEDEEEDDDDDDDCDDBDCDDDD@ADDCCDADD
@34S
GCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCAT
+
@C@FFFFFHHGFHGGHIJJJJJIJCFHIHHIIIJIGHIIJIJJJJJIGIIJIJJJIJJJJJGHFIIEHHGFFFFDDBDDDDDDDDDEDDDDCDDDDDDCD
@34T
GGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGC
+
@<?DDDDDFF3AF?;F<E@<@+A81ACFEEEG=D>FGFFGF@F3?B:DF7BF9=FE37CA7=CE;7(?@B;>;A>;>;@AB@@:A>:::?5???BB33?
@34U
GGTCGTACAAACTGCATCAGGAGATATGCAAACATATCAGATCCGAACTACACCTTCAGCTACCTCTCTGCCACAAACTGTGGTGATGACATCTCCTGTG
+
BC@DFDFFHHHGHGIIJIJJGIJJIJJJJJJJIJJJJJJJJIJJJJJJJJJJJJJJJJJIJJJJIJJHHHHHHFFFFDEE>CE=BDDDEDDDDDDDDDCC
@34V
CTTATTCAAACATCAACAACAGGGACCAGATAATTTTTATGGTGGGACGAGGATACCTGTCTCCAGATCTCAGTAAGGTACGGAGTAACTATCCAAAAGCC
+
CCCFFFFFGHFHDGGHGIIIIJJJJJIHIGIIIHGJJIJIIJHGHIEIH>FGEGGGHHHEHHHFFFBFFEECECECDD;@AB=5;<AACACCDDDDDD>8A
@34W
CAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGAC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJIJJIJJJJJJJJJJJJJJJJJJJJIJJGJJJJJJIIJJJHHHHHFFDDDDDBDDDDDDDDDDDDDDDDDDDDD
@34X
GGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCAC
+
@@@FFDFFHFHBFIGIJGGHHGGFHGIJGII@GHIGIIIIIIJIIJJFIJGGI8:CEFEDECEEC>CDEDDDDDDBBBDD?BBD<?ADDDDCDADDDDED
@34Y
GTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACA
+
C@CFFFFFHHHHHJJIIJIJJJJJJJIJGIJGJIJJJJJJJJJJJJIJJIJJJIJJJJJJJJJIJJJHHHEHFFFFEEDDDDDDDDDBDCCCCDDDDDD
@34Z
AGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATAT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJIHIJJJIJIIIJJHHHHHFFFFFFEEDDDD@DDDDDDDDDDDDDDDDDDDDDDDD
@350
CTTGAAGAACAAGACCACTTATTAGAAGATTATCAGAAAAAGAAAGAAGACTTCACAATGCAAATTAGTTTCTTGCAAGAGAAAATTAAAGTATATGAAAT
+
CCCFFFFFHGHHHJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJIJJJIJJJJJIJJJJJJJJJJJJHIJJJJJHHHHHFFFFFEEEEEECDFFEFEEDD
@351
CCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCT
+
CCCFFFFFHHHHHJIIJIJIJJJIJIJIIIJJJJJJJJJJJJJIJJJ7CHHHHFFFFFFEEEEEEDDDDDDDDDDDDDDEDDDDDDDDDDDDDDDDDDDDD
@352
CCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGG
+
CCCFFFFFHHHHHJJJJJIJIJJJJJJJJJHIJJJJJJJIIIIIJIJJJJJIJJJJJJJJJIIHHHFFFCFFEEFEEEDDDDDDDDDDDDDDDCDDDDEDD
@353
TTACAAGAACAGATTGTGCAAAAGAACCAAGAAATAAAAAACATGAAATTAGAGCTGACTAATTCTAAGCAAAAAGAAAGACAGTCTTCTGAAGAAATAA
+
CCCFFFFFHHHHHIJJIIJJJJJJJJJJJIJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHHHFFFDEEEEDDDDDDEDDDDDDDDDDDD
@354
CCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGACCCATGGATGAAGGACCAGATCTTGATCT
+
C@CFFFFDDH>FHEHJJIGDHGIIIIJJJJGCFE?BBHGIIIIGGBFGIJJIJJJIHIIJJJDFCEDCDDBADDECDDDDDDCAB??ABBDDCDDDDDE
@355
CTTCCTGATGTGAACCTTATTGGGGAGCATTCTGATGCAGCAGAGCTTGGAAGGATGCTTCAGCTCATCTTAGGCTGTGCTGTGAACTGTGAACAGAAGC
+
???DDDD:ABD:DCE:<?CFF@@3F8@:;?E<BDD<DF4DD000B3?<BD<B@DDDDCDCC==7A;;@?==?;=@D>;;;;(>9;;;;A>;AAA>?:AAA
@356
CTGGGCTTCAGGGGGCTGGGGGCGCCGCTTGCCTTGGAAAGGTTTCTTCTTCAGGAAAACGGGCAAGAGAAGTGCATGGTGGGCAGGAGCAAGCCCT
+
==7?AAAA;+@7A<)?A==?AA06AAA@=6=5;5=;;;;===55;====:8::??:<:;?5;7;=;832;83+883889+325930)22899;;<;;
@357
GGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTT
+
?71ADDDDFDHHHIEGBBGFHGDEGGGFCEGCHHIGGGGHDHGGIIIGECGGIE@E>;CDFEFGCAE>CEEE>@3?CDC@ABB@BBBBBCCCDCCCC@AC
@358
CTTCTGAAGAAATAAAACAGTTAATGGGGACAGTCGAAGAACTTCAGAAGAGAAATCATAAAGACAGCCAGTTCGAAACTGATATAGTACAACGAATGGA
+
CCCFFFFFHHHHHJJJJJJJHHJJJJIJJJJJJGHIJJJJJJJJJJJJJJJJJIJHIJIJJJIJJJJJHHHHHFFFFDDEEEDDEEDCDDDDDDDDDDDD
@359
CGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCG
+
CCCFFFFFHHHHHIJIJHHIGHJHIIIJJIJJJJJIJJJJJJJJJHHGFFFFDEFEEEEDDDDDDDDDDDDDDDDDBDDCDDDDDDDDDDDCDEDDDCDDD
@35A
GAGAAACTTCTGTTAGTAAAACACACAGGTCTGAAGACAGGGCCACAGGAAAAGAGAAAAAGAAAAAGGAAGCAGAGGAAGAGGAAGAGGAACTCTCCAAC
+
;;<5?94@?>>1?@18):.>)8(66>5:>2)).):)>1>3((:?1(((.((0).(..)86.'8<>0:59(8(67=9;<7(35;;3(,(,((2+2+3+2:82
@35B
GGGAGACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTT
+
<@<DD<DDDHHDHFD9<CFHHBFFGG:DGDFHAB=FFHIIIACGGEEHDEDCCCBB@CCCBC@ACCCC@A>@CBBCACCCCBBB05<<?>BB@CCC:@>:A
@35C
ATAAAAAACATGAAATTAGAGCTGACTAATTCTAAGCAAAAAGAAAGACAGTCTTCTGAAGAAATAAAACAGTTAATGGGGACAGTCGAAGAACTTCAGA
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJIJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJFHHHHFFFFFFDDDDDDDDDDDDDDDDDDDD
@35D
GAAAAAGAAAGAAGACTTCACAATGCAAATTAGTTTCTTGCAAGAGAAAATTAAAGTATATGAAATGGAACAAGATAAAAAAGTAGAAAACTCAAATAA
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJGIJJJJJIJJJIJJJJJIJJJJJFHIJJJJJJIJJJJJJJJJIHHHHHFD@CEEEDDDDDDDDDDD
@35E
CAACGGGGAGTTCAAAATGACGGACCCCGATGAGGTGGCCAGGCGCTGGGGCGAGCGGAAAAGCAAACCCAACATGAATTACGACAAGCTGAGCCGGGCCC
+
CCCFFFFFHHFHHHIIJJJIIIIJJIGGIGHJJIFBFGIJGGIJHFBEDDCDDBBBBB@BDDCBDDDDDDBDBDDCDDEEDDDD@<BDA@CCDCCDDDDDD
@35F
GAATCTTTTCATGTTTTATATTTTGGGGAAATAAAACACACGGGCATCGCAGCGACCTGGTGGTTTTGGGTTGGAGGGGCGGGTATTGGGTGAGAGTATTT
+
+11++2,2+,,,,2A,7=,3,,,,3)))?0:*:**111)0)0)0((8)'-(''''-',5(.(,,((,(,3(5'&((+0&)&)&&&(+((++&++(((+(((
@35G
CCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCC
+
@@@FFFDFHHHGHJEHHGEHGGIDGHIGJJJJIGFGIJGGIJJGHGGIEIIHIJJJJGIIIIFHHFFDFECCDDDDDDDCDECDDDDDDD8?BDD@CCCCD
@35H
CCCCTTCCCACCACAAGGCTTTAAGCAGGAGTACCACGACCCAGTGTATGAACACAACACCATGGTTGGCAGTGCGGCCAGCCAAAGCTTTCC
+
@@@DDDDDHFHH?GIIHBGHIIIIIEHHIIIFFHHGIGHIIIIIFHEGHGII@CGHH;CEHHHEDEDCACCBCCCBBBB@BB@BCCCCCCCCC
@35I
CTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGT
+
CCCFFFFFHHHHHJJJJGJJJJJJJJJJJJJJJJJJJIJJJJJIJJJJJIJJJIJIJJJJJJJJJJIHHHHHHFFFEDEDDBDDDDDDDDDDDDDDDDDDA
@35J
CAAGATTGGAGACTTCGGGATGGCCCGAGACATCTACAGGGCGAGCTACTATAGAAAGGGAGGCTGTGCCATGCTGCCAGTTAAGTGGATGCCCCCAGAGG
+
@<@DDDDABHHDFGG?C@A1@C<CCBD??@GDBHCF<B?;FH;'55:;?@;??@;;;CA=5>;?2<@CC>C@CA:>:?>@4::::4::>>CBCC<>@<<?<
@35K
CTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCC
+
@@@DDDDDHFFHDGHGIJ@BFGIEDGGCGHGIGGGGIEGGBBH@DHHIGCFHIIEEHGIECEEHHDFFFFCEDCDBD:;BDDBCACDCDDDBDBC?CCD
@35L
CCACTCTTTCCCCAAATTCTCGCCTCTATTGAGCTGCTGGCCCGCTCATTGCCAAAAATTCACCGCAGTGCATCAGAACCCTCCTTGAATCGGGCTGGTTT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJIIJJJJJJJJJJJHHHGHHFFDDCDDDEDDDDDDDDDDDDDDDDDDDDDDDDD?CB
@35M
AGAAGCGGCAGCTCAGCTTGGACATCAACAAGCTCCCCGGCGAGAAGCTGGGCCGCGTGGTGCACATCATCCAGTCACGGGAGCCCTCCCTGAAGAATTCC
+
CCCFFFFFHHHHHJIJJJJJIJJJJJJJJJJJIIIIJJJJJJHFDDEEDDCDDDDDDBDD?BDDDDDDDDDDDDDDDDDDDBDDDDCDDDDDCCCCDDDDD
@35N
CTGTATGTTTGAAAAGGGCCCCAGGCAGTTTTATGATGACACCTGTGTTGTCCCAGAAAAATTCGATGGAGACATCAAACAAGAGCCAGGAATGTATCGGG
+
CCCFFFFFHHHHHJJJJIJJJIJJJJJJIJIJJJJJIGIJJJJJJJIIJIJIJJJJIIJJJJJJJIHHHHHFFFFFEEEEEDDDDDDDDDDDDDDEFEDDD
@35O
GAAACTCTTTCATCTGCTGCTAAAAGTGGTACAGAAAAAAAGAAAGAAAAACCACAAGGACAGAGAGAAAAAAAAAAGAGGAATCTCATTCTAATGATCA
+
@@@D?ADBFD,2ACACFGFFI?IHFHFHI<F+CCA?111:?DBFB8BDB=FF5CF@666.67?=;.;BACCCB;85@309822(:444++:4(4+4@4+(
@35P
AATTGAAATACTCAGACAAGAAGAAAAAGAAAAGGGTACACTTGAACAAGAAGTTCAAGAATTACAACTTAAAACAGAATTGTTAGAAAAACAGATGAAGG
+
@@@FFDDFHGHHFBGGGDHGB;AFHIGIIGCCIIII:DGIIGIEGGGGIIIGG8CGGCHHIIIIIIIIGDGHHE@AD@DFDFCCCC@CACBBACDCC>CCD
@35Q
CTTGATCGTCAGCTGAAGAAAACTACAGAGGAACTAAATGAAGCTTTGTCAGCAAAGGAAGAAATTGCTCAAAGATGCCATGAACTGGATATGCAGGTTGC
+
@@@DDBD=AD?FH>BFHHIHAFGGHFF>EC@?81?D>BABGCEHIGG9?<?DFGID9>BH9CGIGG4@@;CHEBA)=@C>@DCCC6>;ACCC@>AC?<@9(
@35R
GTCGTACAAACTGCATCAGGAGATATGCAAACATATCAGATCCGAACTACACCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATGACATCTCCTGTGAC
+
@@@FDDFFHGHGDGIGFHIFHGGHIECGIBGIIJJGGGJJIJJIIGIIHHIIIIG@GHIIIJIGIGIGGIFHAEFFFEFFEE>ACDCDCCCCDDDCDCDDC
@35S
CCTTTACAAGAGAGTCAGGAGTCTTACACAACTGGGACTCCCAAAGCAACATCTTCTCACCAGGGCCTTGGAAGCACTTTGCCTAGAAGGGGAACCAGGA
+
@@@DDDDDBDBDBGEE9<?@;CGGIIIGEGIFFH?C1:8BDF>GB@FBDDHIIC8C@BFHEIIG>EEEEEEEE@B;ACCCCCC;;;;@><8:=?<B82?@
@35T
GGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTT
+
@@@FFFFFFDHHHIIIIJGIIJJHIGIJJJJ@HEFHF@HDFGFGGIEHGHIJIGHGGHGG>EHHHGHFFFFDCCDBDDDD@DDDDD@C>CCCABD(59?C
@35U
GTCCTCCAGGCCTTCCGCCTCAGCCTCCACCACCAGTTGCTCAACTGGTCCCCATTGTGCCCCTGGAAAAAGCTTGGCCAGGGCCACATGGGACAACCGGG
+
;?81B?AB?CBD<B<BFBBA@FECGBFBEFFF?BG@:9<DFGCFFFFI@CCFCF@FD=CCAED9AA>@BBDCCACA=;>A5;:<<B<B::??98??B@>BB
@35V
CAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCT
+
@@@DFFFDHF>FHIHIIIIIIBFDHHIIIIIIIGIDDHGGHIIIGIIIIIGHIGEGGGIIEHFHGHDFDFDCCCCECCCDDEDDCDDB@BDCDDDDD?BA
@35W
TACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCT
+
@@@FFFFFHHGHHJJJJJIIIIJJJIIJIJJJJJJGIIJIJJJFHIJJIJJHGHCEEFFFFFFEEEECEDDDDDDDDDDDDDCDDCDDDDDDDDBDDDDDD
@35X
CTTACTACAAGCCAAACAACAGATCCTCACTCATCAACAGCAGCTTGAAGAACAAGACCACTTATTAGAAGATTATCAGAAAAAGAAAGAAGACTTCACA
+
@@@DDADDFHFHHIII<GIBFCHIIIGHIIGGCEHGGHIHGIGDIIEGIGGIEIHHHBFHCEHADAHHGFCHHDHCEDEEECCC>@BCACBC?CC>@C5@
@35Y
CTTCTCACCAGGGCCTTGGAAGCACTTTGCCTAGAAGGGGAACCAGGAATGCCATAGTTCCGAGAGAAACTTCTGTTAGTAAAACACACAGGTCAGCAGAC
+
=81=:=ADD?A+@AA?2<<<<32CFCE<?<?*?D9CF;)))90(0B?8.8BDI;....7@DA:A'55;>A@A6>ADAB3>>;55>?=<3558+++3(+2(2
@35Z
AGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGC
+
@@@FFDFFHGGHBGGGIDGGHGIJIJJHIJJJEIIGGDHIFIIIIJIJHGIIJIJJJJJJIJJDEEEC;C@DFEEEE>CCECCDDCCACBDDCCCDDDDB
@360
TAATGATCAAAGTCCACAAATTCGAGCATCACCTTCTCCCCAGCCCTCTTCACAACCTCTCCAAATACACAGACAAACTCCAGAAAGCAAGAATGCTACTC
+
CCCFFFFFHHHGGJIJJJJIJJIJJJJJIJJJIIJJJJJJJJJIJJJJJJJJIJJJJJJJJJJJJJJHHHGHGFFFFDEEDEDDDDDDDDDDDDDDDDDDD
@361
CCTGGCTTACATGAACCACATCATGGTCTCTGTCTCCCCGCCTGAAGAGCACGCCATGCCCATTGGGAGAATAGCAGACTGTAGACTGCTTTGGGATTACG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJHHHHHHFFFFDEEEEDDDDDDDDFDDDDDDDDDDDDDDDDDD
@362
CCGAGTCGTCCATGTACAAGTACCCTTCTGACATCTCCTACATGCCTTCCTACCATGCCCACCAGCAGAAGGTGAACTTTGTCCCTCCCCATCCATCCTCC
+
CCCFFFFFHHHHHJIJIJJJHHJIHIJJJJJJJJGGIJJJJJJJJIIJJJJIJJHJJJJJJJJIJIGIGGFH=EHFFFFFFECEECEDDDDDDDDDDDDDD
@363
TTTCTTTTGAAAATATGACTGTTGGAGAAGAAAGTAAGCAAGAACAGTTGATTTTGGATCACTTACCATCTGTAACAAAGGAATCATCACTTAGAGCAACT
+
@C@FFFFFFHFDFIJJJIIFIGHHHIHGGGGGIHJJIGEIEHJFHHI<FFCFGHIJEIGIIJEIIIIEIIII;CEGHHHAHFFFEFCCCCEEECCDCC?AC
@364
GTGATTCCCTGTGGAGGCACAGTTGCGGCAGCTGCCCTAGAAAAGAGAAACTATTGCAGCTTGCCAGGACCTTTGAGGGCCAACAGCCCACCCTTGAGGTC
+
@B@FFFFFHGHHHJIHJIJJJIHGJIJGIIIGFGIJIGIIIIJIECGCFHIJ@EIFGFHGFHBBDFFDBDDCDDCD?CBBDDDD@??BDD<@BBDD>CC39
@365
CGTGGATAATGTGCACCATAACCCTCCCACCATTGAACTGTTGCACCGCTCCAGGTCACCTATCACGACAAATCACCGGCCTTCTCCTGACCCCGAGCAGC
+
@@@D?DDDF>BCF<FGG;HEHGHDGIGIIGE??D4FCHG?G9<?F>?DFFII>CAFA>EC=;@7..5ABBBC>>C@?BBBBBCC>:>>@>CABB>&0<09<
@366
TCATTATTAACCACAACAGGGCAGAAAATGTACAGTCATGTGATACTCAAGTAAGCTCTTTATTAGATGGAGTTGTGACTATGACAAGCAGGGGTGCTGA
+
@?@FFDFFHHHHFADHGHEGGGGGGIJGIGIGIJ>FGDHG9?<DGIJGHHEFHHIEGIEGIEIG>FFCHG=E@HG=ACCEEEDFDDDD?ACDBD8?BDC>
@367
CTGGGGAGAGGGACGATGTCTGTCTCAGCCCAGGAGTTTGGCTGAGCAGTGAGATGGATGCTGTAGGCTTGGAGCTGCCTGTACAAATAGAGGAGGTCAT
+
CCCFFFFFHHHHGJJIJIGIIIGIJJIIJJIJJJIIGIJJJJJJJJIIJCHIIJHHHGFHFFFFEFEDEEDDADDDDDDDDDDDEDDCDDDDDABB<ACC
@368
CGGGACTCGAGTGATGATTGGGAGATTCCTGATGGGCAGATTACAGTGGGACAAAGAATTGGATCTGGATCATTTGGAACAGTCTACAAGGGAAAGTGGC
+
@@@FDDFFHHHFFHGIJGIIIIIJEGEDHHHFHGGGEEGGGHIICHBFHIFHGGIIFIIJGG=@@CCECECBDEDFD@CEBEDCDDCCACDDABBDCDCD
@369
CAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCT
+
CCCFFFFFFHHHGIIIJIJJIJIGIHIGJIJIJFIIJJIJJIJJJJJIJIJIJIJJJIIJIGHGHGFFFFEECACEEDDD@CACDDDDBDCDDCCDDBDA
@36A
GGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCAC
+
@@@DFDFFHFDDDHGDGHIJJI@GI<CHEGIB?DFBAFDBHHIJIJIJGFHGIJCCCEADCEEHHFBD???95>CCCCD??@BCB@CCCDDBB5<::ABCC
@36B
CTTTCTGAACCCTGTAACTCCTTTCCTCCTTTGCCGACGATGCCAAGGGAAGGACGTCCTATGTACCACCCCCAGATGCCTGAGCCAAACATCCCCTTCCC
+
@@8AB?=22=CDFE<22<AAA<A?F<FB<F4<*CGE6F?087???..-(..-(.=A5>(?;7....66(5',38?<,((5,>39:AA99?<A:9<?<8??<
@36C
GGGTGACAGTGCTTATAAACGAAGACAAAGAGTTGGCTGAGCTGCGAGGTCTGGCAGCCGGAGTAGGCCTGGCTAATGCCTGCTATGCAATACATACTCTT
+
=@@4=;?DFFHFDEHEGEFBDHICGE@EFH9???FAGABFGEGGHE@@F@CHB>GGH@?EE6>5>@CCCC?BBCCCCCCCCCBCCAC>@CCCCCDBCACCC
@36D
CAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCC
+
CCCFFFFFHHHHHJJJJJJJJJJHIIJJJJJJIJJJJJJJJJJJJJJJJJJJHHHHHEFFFFFEEEEEEEDDDDDD@CDDDDDDDDDDDDDDDDDDDDDDD
@36E
CCTGACCCCGAGCAGCGGCCCCTCCGGTCCCCCCTGGACAACATGATCCGCCGCCTCTCCCCGGCTGAGAGAGCTCAGGGACCCAGGCCGCACCAGGAGA
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJHHIJJJHHFFFFEDDDDDDDDDDDDDDDDDCDDDDDDDDDBDDDBDDCDDDDDDDDDDDDBDBBDDDDDDDDB
@36F
TATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTT
+
CCCFFFFFHHHHHJJJJJJIJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJHHFFDEEEEEDDDDDDDDDDDDDBBDCDDDDDDCDAC
@36G
CGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCC
+
BC@FDDFFDHHFHGHHHGE?FFHHIHGCHGEHIJJJFGHGEHJIIIIJHHEHEFEBBFBC;>@ADDDDDCDBBDDDDDBDB?BDCC>CDEDDDCCDDDDD
@36H
CAATCACAGTGTAATGAAATGTACATAAATAGTTCTCAGAGAGTAGAATCAACTGTGATTCCTGAATCTACAATAATGAGAACTCTACATAGTGGAGAAAT
+
CCCFFFFFHFFHHIIJJJJIJDIIJJJIJJJJJJJIJIJJJJJHHIIIJJJJJJJJJJIJJJJJJJEIJJJIIJIIJHIGIIGEIGGGGHHGCDFFDDEE>
@36I
CAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATAT
+
C@CFFEFDCDHDFHGHICFHHHGHGIJIJGGGGGEHIDFEHIIJGEHIEEHGHJEFBHIJEHJIGGFHFDFCDFCDECEDDDDCDBCCDDC@:@>@DDD
@36J
TGGAAGTGGTGCAAACAGAAAACCAAGTCATACCAGTGCTGTCTCAATTGCAGGAAAAGAAACTCTTTCATCTGCTGCTAAAAGTGGTACAGAAAAAA
+
@?<D1A=BF=A>DGGIIIGGFEECFG?2:?FF99?BFD>DBGDC<GEHGIIEG;?FHGCDFACE@=7@CHIIIE3.?;;@DEB@.6@@C>CDCC@=B?
@36K
ATTCTTCTGATAAAGTATCTAAACTAGAAGGTCAAGTAGAATCTTATAAAAAGAAGCTAGAAGACCTTGGTGATTTAAGGCGGCAGGTTAAACTCTTAGA
+
@@@DDD?DFB?CDFE,<CID<AECHHCDE@D2A?BE?C??1:C9?CFHH@@??FBFG<DFIDBCBGIG@F.;@CGEHIIGEHC:;@?BCCCC>C::4>:4
@36L
CTCGATGGAGTGGGTCCCATCAGTTTGAACAGTTGTCTGGATCCATTTTGTGGATGGCACCAGAAGTCATCAGAATGCAAGATAAAAATCCATACAGCTTT
+
BCCFBFFFHHHHHJIJJJJJJJJGIJJHIIIIHIFFIJJJIIIJJJGJJJFGGFHJJJIJJJJIJJHIHHHEFHHHFFFFFFEEEEEEDDDDDDDDDDDDD
@36M
GACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJIJJIHHHHHHFFFFFFEEDEEDDDDDDDDDDDDDDDDDDDDDDDDDD
@36N
GTTGGGGCATTCAGAAAAACAGGCCAGCTATGAACTATGATAAACTTAGCCGTTCACTCCGCTATTACTATGAGAAAGGAATTATGCAAAAGGTGAGCAGC
+
@@@FDDDDHHHGHFIIJJIJJJJIJHEHHIIGIIGEHHFHIIGIJI@GGIHB7AGGGIJIGIABDFEFFFFDACCEECDDCDCDEDDECDDCB5@CDCCCD
@36O
AATTCAGATGACATTATGCCAGTTGCTTTAATGGAAACGAAGAACCGAGAAGGGTTAAACTATATGGTACTTGCTACAGAATGTGGCCAAGGTGAAGAAA
+
@@@DFFDDHFHHHIIGADG:FHCHEEHIIIIGGHEIGIIIII<F>FGDDHBGGI@FGEHGIIGIEHF7=??B@>CD>@CEE@@>>@ABCBBBACC@C@CC
@36P
ATTCCACAAAGCCACAACTGGCTATTGTTACCCAGTGGTGTGAGGGCTCCAGCTTGTATCACCATCTCCATATCATTGAGACCAAATTTGAGATGATCAA
+
CCCFFFFFHHHHHJJJJJJJJJIJJJEIIJJJJJJIIJDHGIJJJJJJJJJIJJJJIIJJJJJIJJIHHHHHHHFFFFFFDEDEDDDDDDEDDDDDEDED
@36Q
CCGCGATGTGGTGTGGGGGACGCCAGTGGCTTGGTAGTTCCCCACCCGCCGGCGCCACCGGGTAGCCAGGCAGACCCCTCCGGGACGGCCGGGCGTTCCTG
+
17++2)002222++?A<1:)08)0<'8AB=(.-().=.)7=>=;@<',''3'0&&)&0(&&&)&((+(+8(8(+(+++(&()0&0&&&&&&)09.&)23(3
@36R
ACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGT
+
CCCFFFFFHHHHGJIJJJGIIJJJJJHIJJJJJJJJJJJJJJJJJIJJJJIJJJJJJJIJJJJJJJJHHHHFFFFFDEEEEEEDDDDDDDDDDDDDDDDDD
@36S
GTCCGCAGTTGGAATTGTGACTGTCATATGTGAACATCTGGCTACAGTTGGGATGGTGACTCATTTCTAAATCCAGCTCATAGGAAGGTGAAGACTCTCCT
+
B@@DFDDFHHHDFIJJIIJJJIJIJJIFGIEHIGIIJJJIHIHGGIIHHIJIICFGFGGIGIJHJJJIJIIFIHHGFEHFEDFFCDED>>@CCDDDDDCDD
@36T
ACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCAC
+
@@@FFBD?BHHDDFBBFEFHIIGG:FGC?G?DFGGHGGEGIADHE<FHDG<B9?BFGHGGIA@FHCCGHHA?AHEFEFDCC@CEBC?BCCBBCB8?BBB@?
@36U
CAGCAGAACAGAAGGCTGTATGTTTGAAAAGGGCCCCAGGCAGTTTTATGATGACACCTGTGTTGTCCCAGAAAAATTCGATGGAGACATCAAACAAGAGC
+
@@@FBDDDFFDHDGGHIIFHIIFHHGGIIIGHGHHHIIIIGIIFHGIIIIIGHIEHIIIGCHGGIEHGHFCBFFFEAEED>CCDCDCDDDDDCDCBDCCBC
@36V
CCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGAC
+
;?@DDDD;F:CD<EGFFIFEIIEEGGEFFFFIIFIEFFIIIIIIFIIIFIDFCCEGEEFEFGCFDCEACA;>@>;ACBC?9>BB7?B@@BBB>BDDEAB<
@36W
GCGAGAGGGAGACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTAC
+
@@@DFFFFHAH>FHGBHHDHGEFGH<B>FGGHFHG@FFGGGGFGCCC>>CDB>BB@CBDDDDDCCDCCDDCDDDAC>CCBDCDBCDABDBDBDDDD@?A?
@36X
CAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCT
+
@@@DDA?A;ADDFAFBHIIIE@B+CCFHCHIHEDFIIIEIEGEHEHEBHCH@CFGGI@CAHIFEHE=DEECCCCC@CC>CCC>@>><?B93:?@ABBBAC
@36Y
CTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTC
+
CCCFFFFFHHHHHJJJIJJHIJJIJJJJJJJJJJJJJJJJJJJJJJIJIGIIEEHHHHFFFFFFFEEEDEDD@CDDCDDDDDDDDDDDDDDDDDDDDDDCD
@36Z
CAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGG
+
C@CFFFFFHHGHHIJJJJJJJIJJJJIJJJJIJJJJJJJJJJGIJJJIJIEHIJJJJJJIIJIIIIJJJHHHHFFFFEDEEEEDDDDDDDDDBDDDDDDDD
@370
CTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCT
+
CCCFFFFFGHHHHJJJJJJJJJJJJJJJJJIJJGHIJJJJJJGHIJJJJJGIJFIJJJJJJJHHHFEFFEEDDEDDDDDEEDDDDDDDDDDDDDDDDDDDD
@371
CTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCT
+
@@@FFFFFHGHDHIJGGHHIJJEGGBHIIJDHIGJJIJJJGIJJJGHHGIIGIICACFGIJIGIJ@DEEEEDFFCBB>A>@>CDACCCCC@CDDCDCDCC@
@372
AGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCAC
+
;;=AAAAA==;7>+211@7?<A?AA<BBBBABBAA=AA<<>ABB:A>3AB;<AA<A>;59=6>>;?-;3==B????=6;0;9<=;<;83833:<????=3(
@373
GTCCATACCAGATAGCAGCTACCCCATGGACCACAGATTTCGCCGCCAGCTTTCTGAACCCTGTAACTCCTTTCCTCCTTTGCCGACGATGCCAAGGGA
+
BBBFFFFFHHHHHJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJIJJIJJJJJJJJIHHHHFFFFFFEEEEEEDDDDDDDDDDDDDDDDDDDDDDDDDD
@374
GCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACC
+
C@@FFFFFHHGGGIIJIIIJJJJJJJIIJIIIIJGHJJGIIIIIJJJJIJJGJIJJJJIJJGGIJEEEEEFFFEEEEDEEDDDDADDDCDBDBBDCDDCD
@375
GGACAGTCGAAGAACTTCAGAAGAGAAATCATAAAGACAGCCAGTTCGAAACTGATATAGTACAACGAATGGAACAAGAAACACAAAGAAAGTTAGAACA
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHIJJJJJJJJJJJJJJIJIJJJJHHHHFFFFFEEEEEDDDDDDDDDDDCCDDDDDD
@376
CCCAACGACCCAAGCCCCCTGCAAGTGGCTGTGAAGACGCTGCCTGAAGTGTGCTCTGAACAGGACGAACTGGATTTCCTCATGGAAGCCCTGATCATC
+
:7+?+7<+000<AAA=<<A):=?7?*?:?A;A*:0/=B7=7'-=.>3=7...7=A>.).;3;7((;3'9'(,95(9;?>+(+8?::3998289838=:8
@377
CTAGCAGCGGACAGTACATTGCCATTGCCCCAAATGGAGCCTTACAGTTGGCAAGTCCAGGCACAGATGGAGTACAGGGACTTCAGACATTAACCATGAC
+
>=77;?<@<7)<0<AA<<C+*11:*:7=>=;;;:<?B=5377?<A>B=A9A>A;AA4>=;AAAA>.>))).6>9>??=1((,59??(95;?>?;=?=;??
@378
GGCAGATCCAGCTGTGGCAATTCCTCCTGGAGCTGCTCTCCGACAGCGCCAACGCCAGCTGTATCACCTGGGAGGGGACCAACGGGGAGTTCAAAATGACG
+
C@@DFFFFFBBHGIII@@FDFHHHEHGAF@ECGBHGGIIIF?FBG<A7AG@G=CBDFFCECA>@DCCCCCBB<<@=99<?ABCCBBB<@BCCCDAC@CCC8
@379
CCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGGTACAACCAGCCCAGCCTAGGATATGGACAGAGTA
+
@@CFDDFBDFFFADGDEHEIGBGEFFDHICDB;BGICHEFGGFGBHEDFGGHICCHIIGFHHCDC&05ACACDD?A@??<<B<>CC@>CDCCCCCD>A4:
@37A
GTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTAT
+
BBCFFFFFHHHHHJJJHJJJJIJJIIGIIHJJIIJJJJJJJIIJJIHIJIIJIJJIHHHHFFFFEEECEEEDDDDDDDDDDDDBDDDDDDDDD@AACCDDD
@37B
AGAACAGCTCCAAGAAGAAACATTCAGACTAGAAGCAGCCAAAGATGATTATCGAATACGTTGTGAAGAGTTAGAAAAGGAGATCTCTGAACTTCGGC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIIJHGIJIGIEHFHHHFFFFDDDEEEDEDDDDDD>@DD
@37C
CTAAAGGTGTATATCAAATCAGCAAACAAATCAAAGCTCATGATGGCAGTGTGTTCACACTTTGTCAGATGAGAAATGGGATGTTATTAACTGGAGGAGGG
+
CCCFFFFADDHHHJJJIJJJJJJJJJJJJJJJJJJJJJIIJJJJJIJJJFHFGIJJJIIJJJJJGGIJIIGGGIIJIHHHHFEDDFFFEECEEECBD?DDD
@37D
CAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCT
+
@CCFFDDFDDHDFGHEGDFGGFGBFGGCFIHIIIGICGGCIIHIIIICGCHI>FEGGGIEE=;BBEEC@C??=?BB@?CCD>>CCDCAACDBACDDDDC
@37E
AGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGG
+
@@<DFDDAHDDHDAFGIFIFGEFHGGIDE?FHHI@GEAD<B<@BGEHCEGGIGHI:@AF@DGGA=EEFCEDDFFC@;>>CEECCA@CDDCDC?CB>CCDC?
@37F
CAACAACAGGGACCAGATAATTTTTATGGTGGGACGAGGATACCTGTCTCCAGATCTCAGTAAGGTACGGAGTAACTGTCCAAAAGCCATGAAGAGATTA
+
CCCFFFFFHGHHHJJJJJJJIJIIIJIJJFHIJGGGEGHHIIIIHGGHGGIIGIGIIHGFAEHHF@CEFDD?=>ACDCCCDDDDDCABDCCCDDDDDDCD
@37G
GAAAGTGGCATGGTGATGTGGCAGTGAAAATGTTGAATGTGACAGCACCTACACCTCAGCAGTTACAAGCCTTCAAAAATGAAGTAGGAGTACTCAGGAA
+
C@CFFBDEHFHHHFHGHGHHHEHIEHHGHIGGGHIIIIJHIEGGIGIEGHEFHIIIGIIJJIFGGGGIGCHHHEHHHHHFEEFEC@ACC@;>CCCDCCDB
@37H
TATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTC
+
;?8BDDDAF>FFFFFEFD8?<CGFDBFFEBGFICGFD>?:B9D<4BF<FECFC@8=;@;C48(6@@=C<'9>@=?AB>;5@5:89<?<9:@@A>:::4+:
@37I
CTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATG
+
CCCFFDFFHHHHHJJJJJJJJJJJJJJJJJJJIIIJJJJJJJJJJJJJJJHHHHFFFFFEEEEEDDEDDDDDDDDDDDDDDDDDDEDDDDDDDDDDDDDDD
@37J
GCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTTATGGGCAGG
+
CCCFFFFFHHHHHIJJJIJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJGIJJJJJJJJHHFFFDDDDDDDBDCDDDDEDDD9>>BDDDDDDDDDD
@37K
GGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTT
+
C@CFFFFFHHHHHJJJJJJJJIJJJJJJJJJJJJJIJJJJJJIJJJJJJJJJJJJJFIJJJJJJJJJHHHHHFFFFFFEEDDDDDDDDDDDDEDDDDDDD
@37L
CTGTTTTCCCCTGCCTTCCTTGCAGAGGCCATGGAGGACGAGGAGAGACAGAAGAAGCTGGAGGCCGGCAAAGCCAAGCTTGCCCAGTTTCGACAAAGAA
+
CC@DDFFFHGHGFIIGIIIHGIJICHBDEDGHHIHGDH@F@@G@CGIJIDIIIJIGEHHFEBBBCCDB=?BD?CACD?BDDDDCCDBACDDBDBBDDDDD
@37M
CGGCGCTTTCCCCGCAAGATGGACGGTTTCGCCGGCAGTCTCGATGATAGTATTTCTGCTGCAAGTACTTCTGATGTTCAAGATCGCCTGTCAGCTCTTG
+
?@@DD>DDHD<DAH6@EG3CFHFFHIGGHIGHHGGEEEECCCCCCECDDCACDCDECCCCCCCCC>CCDECCCD>CCCEEDCCCCBBBBBCCCCCCCCCC
@37N
GGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGC
+
@B=DFFFFHHGGHJJJJJJJJJJJJJIIIIIJIJGIJJGIJJJJJJJJJJJJIIJIJGIJJIFFEEHFFFFCEEEEDCCEDDDDEDDDDDBDDDDCDDD
@37O
CCAAGCCCTCGAGCAGTTATTCCCATGTCCTGTATAACCAATGGAAGTGGTGCAAACAGAAAACCAAGTCATACCAGTGCTGTCTCAATTGCAGGAAA
+
CCCFFFFFHHHHHJJJJJJJJIJJJJJJJJJJJJJJJIJJJJJIIJJHHIFHIJJJJJJJIJJJJJHHHHHHFFFFFFEEEEEEDDEDDEDDDDDDDD
@37P
CTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTT
+
CCCFFFFFHHHHHJGIIHIIJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJHHHHFFFFDEEEEEEDDDDDDDDDDDDDDDDDDD
@37Q
CAATTACCATGTTCATTCCTTCCGATGTTGACAACTATGATGACATCAGAACGGAACTGCCTCCTGAGAAGCTCAAACTGGAGTGGGCATATGGTTATCG
+
=8=BDADDFBA?DDFEFIIEDBE<FC@GIHHIIBFE<C?BFFGE@D?9?3B;@DBDFFGIEDFII;CEF@?EFFFBB);;;(666??B;;;@A@(5,::<
@37R
GCTCAGTCTCTGAAAGATGAGATCGACGTGCTGAGACATTCTTCTGATAAAGTATCTAAACTAGAAGGTCAAGTAGAATCTTATAAAAAGAAGCTAGA
+
CCCFFFFFHHHHHJJJIJJJJJJJJJJJJIJJJJJIJJJJJJJJJJIJJJJJHIJIJJJJJJJJJJJJEHJIHHHHHHHFFFFFFEEEEDDDDDDDDD
@37S
TCATAACATTGCTTATTGCTCGTAGATTTGAAGCATTCTTACCCCGGAGTTTTGAGGTTGACCAACCACACAAAAAAAGCCACTTTTTAATTTTATTTATT
+
-(8>36))@@)))):)))@2@-(((()<44)1):))..>.).))(-0-7(<.=(((.<(<?3>?/=9=6/,,=35;22'(2++8<:6</(+++8(+82:((
@37T
CCCAATTGAAAAGAGAAATAAGGTTAATGAAAAACAGAGAAGCTGCTCGAGAGGGTCGCAGAAAGAAGAAAGAATATGTGAAATGCCTGGAAAACCGAGTT
+
@<@D?DDE?CFBD@EHDGHHIIIEE?F@HGHIGIDBFGCFHGCHI>9BG:@9A(<5C;EAEBDDBA@@3;A;>ACCEE;>;@@::3>CC?<@@CCBB@B2<
@37U
GCGCCTAGAGGGAAAGCGAGAGGGAGACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGC
+
@@@DDDFDFHGHHJJIJJDGGHIIIIGJJIJJJHIJDIHIJJIIBHF>BDCEDDABDBBDDD@CCBB@BDDCBDDDDDDDD@CCCDDCCDDCDDDBDDD
@37V
CCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCAT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJIJJJJJHHHHFFDDDDDDDDDDDDDDDDDDDDDEDDDDDDDDDDDDDDDD
@37W
GGAGAAGCGGCAGCTCAGCTTGGACATCAACAAGCTCCCCGGCGAGAAGCTGGGCCGCGTGGTGCACATCATCCAGTCACGGGAGCCCTCCCTGAAGAATT
+
@CCFFFFFHHHHHJIJIJJJJJJGIIJIIJJJJJJEIJJJIJGGDDDDDDDDDDDBDBD<BD8?CCDDDDDDDDDDDDDDDDDDBBDDCDDDCDDDDCCDD
@37X
GAGCACGCCATGCCCATTGGGAGAATAGCAGATGTGCAGCACATTAAGAGGAGAGACATCGTGCTGAAGCGAGAACTGGGTGAGGGAGCCTTTGGAAAGGT
+
CCCFFFFFHHHHHJJJJJJJJEHIIIIJJIJJJJIIIJJIIJJJJJJJGIJJJJJJJJJJIJJGHHHFFFFDDDDDDDDDCDDDDDDDDDDDDDDDDDDDC
@37Y
GAAGTTGTTTTGGCTGTGGAGTTTCACCCAACAGATGCAAATACCATAATTACATGCGGTAAATCTCATATTTTCTTCTGGACCTGGAGCGGCAATTCACT
+
BBCFDEFDHHHGFIJJHHJGIFHIJJGHIJJJGGHGIIIIGJJJJJJJIIJGHGIIJIGIGIIJIIFHHGHFHHDFFFFFEDEEEDDBDCDDCDDDDCDDD
@37Z
CAGAGAGCTAGACAGACAATAGCTGAACAAGAAAGTAAACTTAATGAAGCACATAAGTCCCTTAGTACAGTGGAAGATTTGAAAGCTGAGATTGTTTCTGC
+
@@@DDFFFHHGGFIGHIJIIIIJJIJJIIIJ@FHDGHIHIGHIJJIIJIIGIJIIGBBFGHIIIGDGIHC7@C=CEHEHFHHFFCBDDECEE@CAAA@C@C
@380
GCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGC
+
:>=AA>+7AA+<7<AABBAA72?ABBA;3??;AA><400?BAA>7<>?AB7ABAB7=;BAB>A?;A7==>?@@35<<;>?=;;;=;=9=39;=;3(++2;
@381
CCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGG
+
1:8==ADDD:<<AG@FB<<<E@C12<<2C911C99:DGBGI@B;60090B88D;88B=;FF><:1?;36..;;AD3>6>893<9<9?<?5988(+444::<
@382
TGGACTCGCCAGAGACATCTATAAAAAATGATTACTATAGAAAGAGAGGGGAAGGCCTGCTCCCAGTTCGGTGGATGGCTCCAGAAAGTTTGATGGATGG
+
:=;::=DA:DFFH@BG?BF<EB<CA?G@?GCDDDBA??9?GBHH>G3BGBH64;;;=?C>@B@?6;;@;A>,;;?(>83?>1(::?CC4>@>:@@@3@:?
@383
GATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGCAGGCATATGG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJHGJJJJJIJJIJHHFFFFDDDDDDDDDDDDDDDEDDDDDDDDDDDDDDDDDDDDDED
@384
GAATCATACAGCCAAGCTCCAAGTCAATATACCCAACAGCGCAACAGAAACGAGCAACAAACTGAATCAGGAGATATGCAAACATATCAGATCCCAACTAC
+
7(0-=)@)2=@?77)(:<6)9)2.)))28>8)@)2(1<((-:9-9>()).:1''5;)(.(..))).(((.(.,3(5;1(5(32((5((7,++(2((6+2(+
@385
CGGACGTTGAGTGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCG
+
;(((<3-@((.)2>8)9((8/5;(:;;?<<513=)<3)<'--;=?93'-');=9=;;=1=((690-,,(,82(7(,&0&56(2022(8:(+(+((5++2:5
@386
CCCCAGCCCTCTTCACAACCTCTCCAAATACACAGACAAACTCCAGAAAGCAAGAATGCTACTCCCACCAAAAGCATAAAACGACCATCACCAGCTGAAA
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJIJJIJJIJJJJJJJJJJJJIHHHHFFFFEEEEEEDDDDDDDDDDDCDCDDDDD
@387
CCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTTATGGG
+
C@CFFFFFFHHHHIJJIGGHGGHHJFHIJJIGJIJJGGIJJJJIJJJJJIJIIJJJHIHHGGGHGHHFFDDBDDDDDDDDDD>CCDDDDDD9>5?CDDDDD
@388
AAGCCATTATGATGATGGAGGAATCTGTTCAACATGTTGTCATGACAGCCATTCAAGAGCTGATGAGTAAAGAATCTCCTGTCTCTGCTGGAAATGATGCC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJIJJJJJJJJIIIJIJIJJJJJJJJJIJJJJJIJJJJJJIGJEHIIIJJJJJJJHHHGHFFFFFFEEEEEEDDDDD
@389
GGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATC
+
C@CFFFFFHHHHHJJJJJJJJJJJJJIJJJJJJJJIJJFHIJJJIJJIJJJJJJJIIIDHHHHHHFEDDEEEEDDDDDDDDDDDDDDDDDCDDDDDDDDDD
@38A
AGCTGCTCGAGAATGTCGCAGAAAGAAGAAAGAATATGTGAAATGCCTGGAAAACCGAGTTGCAGTCCTGGAAAATCAAAATAAAACTCTAATAGAAGAGT
+
@C@DBFEDHHHHFGJEGIGIHIJJIIGICGIAHIJGGGGGGGICFHGIJJEIJGHIGEGHHHHFFBBEBDEACCECCCDDDCCDDDCDCDCCCDDCCCC?D
@38B
CCATGCTGGACCTTCTGCACGTGGCTCGGGACATTGCCTGTGGCTGTCAGTATTTGGAGGAAAACTACTTCATCCACCGAGACATTGCTGCCAGAAACTGC
+
CCCFFFFFHHHHHJFGGGIIIEGHIGJIIIIJJJJIIJFGDGGGGIFHGG8@FGGEI>GHCHFFCFFFECEEEDEDC?B@@:=C@CCC>CC@4@ACDD@CD
@38C
GCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACT
+
@@@FD=?DHFDHFIHIFIGIIIGGHIIIIIIIIGE@FGFIGBGIEGGDHIIGGGCFHGIGIHCEEECHBE?ECCCC@@CDCACACCCCA@CCCCCAC?ACC
@38D
CTTCAAGAAAAATTTGCACAACTTGAAGCAGAGAATAGCATTCTTAAAGATGAAAAGAAAACCCTTGAAGACATGTTGAAAATACATACTCCTGTTAGCC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJHHHHHHFFFFFFEEEEEEEDDDDDDDDD
@38E
CGAGAGGGAGACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTAC
+
CCCFFFFFGHHHHJJJJIJJJJJJJJJJIJJGHIIJJJJJIJHHHHEHFEFDDDDDDDDDDDDDDEDDDDDDDEDDDDDDDDDDDDBDDDBDDDDDDDD
@38F
CAGACTAGCAGCGGACAGTACATTGCCATTGCCCCAAATGGAGCCTTACAGTTGGCAAGTCCAGGCACAGATGGAGTACAGGGACTTCAGACATTAACCAT
+
CCCFFFFFHHHHHJJJJJJIJJJJJJJJJJJJJJJIJJJJJJJIJJJJJJJJJJJJJJJHHHHHHFFFFFEEEEEDACDDEDDDDDDDDDDDDDDDDDDDD
@38G
GTCCAGCCTGCACCCCTAAAGCACGGAGGGCGTTGAGCGAATCACCCGATCCCGAGGCGGGGACCGGCCTTGAGACGGCTCTAAGGGGGGGGCCGTTGCCG
+
1112+<+<A+@<<++<A+3?<@AB:A)1?))0.-<=A)'-5'-.7>('''',;(','&&&0-&&+&05;-((+(((()))58((((()000-&&&)&(&(&
@38H
GAGTCGGAGAGCTCCAGTGAGTCCAGCTCCTCTGACAGCGAAGACTCCGAAACAGGTCCTGCCTAATCATTGGACACGGACTCTTAATAAAACGGTCTTC
+
BB@DDDFFHHHGGIJGIGHIJHIJJIJIJJJJJJJJJJJIJIIJJIJJJJJIGHHH?DFFFFEEEEEDDDEDDDDDDDDDDDDDDDEEEDDDDDD<?@CD
@38I
GCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACT
+
1::<<+<3?4+?7?CCA)3?AA;ABA@A1???A77***0?A><ABABBBAB9=>)=>>=;5<B2;:A((55>>@@(55;;>3;>55,5:9>?9=>=9;??3
@38J
TGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTC
+
CCCFFFDFHHHHDHIIJJIIJHHIJGIDEDCGHGFHHIJIGGIIIJIJFGIIIJGGIJICHHIFHFFDDCDBDDDCDDCDDDDD?CCDDDDDDDDDDDDCD
@38K
CTGCATCAGGAGATATGCAAACATATCAGATCCGAACTACACCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATGACATCTCCTGTGACTCTCACCTCT
+
CCCFFFFFHHHHHJJJJIJJJJJJJJJIJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJGHHEHHFFFFFFECEEEEDDDDDDDDDDDDDD
@38L
ACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGT
+
CCCFFFFFHHHHHJJJJJIJJJJJJJJJJJJJIJJJJJJJJJIHIIJJJJJJJJJJIJJJJIJJHGHFFDDDDDDDDEDEEEEEDDDDDDDDDDDDDDDBC
@38M
CTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTAT
+
CCCFFFFFHGHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJHHHHHHFFFFEEDDEDDDDDDDDDDDDDDDDDDD
@38N
CAGCAATGTGAGCAAGAAGGAGCCAGCGCCCATGAAGAGCAAGCCCCCTCCCACGTATGAGTCGGAGGAAGAGGACAAGTGCAAGCCTATGTCCTATGAGG
+
C@CFFFFDFHFHGIGIJEFHJGIGJJIIJJJGIJIJGIJJJIJJIJGGHIJIGGE=AEFFFFFDD>@DDDDDBDDBCDBCCDCDCDDDCDDEDEDDDDDDC
@38O
GTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACT
+
@?@DA?DDFDCDD>EFG;GGI:CHH>BCGBGIDFIIIIFIIDFFG=GCFFF*=BFFFII@FEF46@D@=2AED9BBCCC=AABBA:@;@ABBBABB?BB@B
@38P
CTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGC
+
@<@DFFDFHFHHHIGIIGHIEIIIIJIHCFGHIIBADHIEIGHGIGIGH@FHIJGIIIIJJJAGHGG=A;CEF@?DCABED@DBB=B@DCBCCCDDDCD@<
@38Q
CTGGGGGGCAGTTGGAGTAGTATAACCAGTGGGAGGCTGTCCATAAGAAGTTGCATAGGCGGTCTGCCCATAGGTTGCAGTGGTCTGAGCCTGGGTATAGC
+
@BCFFFFDDDDDDDDDDCDDDDEEEDDDDCCDDDDDDBDDDDDEDDDDDDCDDDDEDDDDDDBDDCDDDDDDDDDDDDDDACD@CCDCDDDDDDD<CDEDD
@38R
AGACTAGAAGCAGCCAAAGATGATTATCGAATACGTTGTGAAGAGTTAGAAAAGGAGATCTCTGAACTTCGGCAACAGAATGATGAACTGACCACTTTGGC
+
CCCFFFFFHHHHHJJJJJJIJJJJJJJJJJJJJJJJJJIJJJJIJHIJJJJJJJJJJJJJJJJJJJJJJIJHHFFFEEEEEDDDDEDDDDDDDDDDDDDDD
@38S
GGACAAGATGCTTGTGGCTGTGAAGGCCCTGAAGGATCCCACCCTGGCTGCCCGGAAGGGTTTCCAGAGGGAGGCCGAGCTGCCCACCAACCTGCAGCATG
+
1+:AD::==C4A?<2<CEF@AEF99E3ABCE@CDC)*00?*9?@29??.76=6;;-5=A'..;(66(66=33,;1</&&))99(+(29<889>8<>((((+
@38T
GAAAAGCCAAAATTTGTGCAGTGTTTAGCATTCTTGGGGAATGGAGATGTTCTTACTGGAGACTCAGGTGGAGTCATGCTTATATGGAGCAAAACTACTGT
+
C@@FFDFFGHHGHJJJFHHJIFGEHIJJJJJJIJJJJIIIJJJJCHJJJHIIJJIJJJJJIIJJJJJJ=DHEHHHGFFFFFFEEEEECEDDDDDDDDCDCD
@38U
TAAAAGAGAAGAGAGGGAAAATTGGGAAGAGGGAAAGTAAGAGAAAAGAAGAGATAGAGGGGGAGGGAGGAGAGGGGGGGAGGGGGTGGGGGAGGAGGAA
+
((((()()))))()-((-(()).24(()(1((((((())0))00)..)-()).)))...('-',',''',((((+)0886&05&)&&&0&)5&&)(()((
@38V
ATGAGCATATGCTTACTGTATGGGACTGGCAGAGGAAAGCAAAAGGAGCAGAAATAAAGACAACAAATGAAGTTGTTTTGGCTGTGGAGTTTCACCCAAC
+
CCCFFFFFHHHHHJJJJJHIJJJJJJJJJJJJJJJJJJJIJJJJJJIIIJJHJJJJJJJJJJJJJJJHHFHHFFFBFFEEDEDD?CDCDCCDDDDDDDDD
@38W
CTCAACTCATACACCGAAACCTGACCGGGCCTTCCCAGCTCACCTCCCTCCATCGCAGTCCATACCAGATAGCAGCTACCCCATGGACCACAGATTTCGCC
+
@CCFFFFFHHHHHJJJFIIJJJJJIJJIJJJGIIJJIGIHGGIIJJIIGIHHGHFFFCACECDDDDDDDCDDDDDDCDDDDDDDDDDDDDDDDDDDCDDDD
@38X
CAGGACTTGATTAGAGACCAAGGATTTCGTGGTGATGGAGGATCAACCACAGGTTTGTCTGCTACCCCCCCTGCCTCATTACCTGGCTCACTAACTAACGT
+
?@@DA?DDBHHHHBEHHE=E;AB:9FD<EEHD??FHHHGGGFGIGGIIGGHIGBFHC@;CHADEGCHFBCBBBBBC@C@>ACCCCBBCCCCCCCCCCC>BC
@38Y
TTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAAC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJHJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHFFDDEEDDDDDDDDDDDDDDCDDDDEDDDCDDDD
@38Z
CACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAAT
+
@@@FD?DBHHFDHJJJEGIAHGIGIII@EHGGIIEFHG;DDGGEHGI?FGGEHHJIE;CGHEHFBDAC?ACC?CBCDDDABDA@C:CCDDACDDCACC@CC
@390
GGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTT
+
CCCFFFFFHFHHHJJJJJJJJJJIJJIJIJJJIIJJJIIJHHIIJJJJJIJIIIJJJJIJJIJJJIIHHHHHFFFFFFEEDDDDDDDDDDDDEDDDDDDD
@391
GTTATTACTATGATAAAAACATTATGACCAAAGTGCACGGCAAAAGATATGCTTACAAATTTGACTTCCACGGCATTGCCCAGGCGCTGCAGCCACATCCG
+
@=@DABEDADDHBHHGHGHGICH>HHFHIIICC1?EHF=:F?DHGGFHGEHHGGGDGHGGIECFGGGIIIIHEFDCECCCCCBB=@BB=<C?CBBCC:>?B
@392
GACCGGGCCTTCCCAGCTCACCTCCCTCCATCGCAGTCCATACCAGATAGCAGCTACCCCATGGACCACAGATTTCGCCGCCAGCTTTCTGAACCCTGTA
+
@@@FFFDFHGFHGJJJFEHCEGFIIIIIJGIGGEBGBGEIIGGIDGGGIIFJIGEEEHFHFFFD@AE?ABDDCDDDBDDB>D@BDDDDDDCCCDDDDCCD
@393
AGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACC
+
CCCFFFEFHHHHHJJJJJJJJJJJJJJJJJJJJGIJJJJJJJJJIJJJJJJJHHHFFFFFECEEEEEDDDDDDDDDDDDDDDDDDDDDDDDDDDEDDCDDD
@394
AAGCAAGTCCTGGGATTGCAGAAAGGACAACAAACAGGGGGTCGTGGAGTGCTTCCTCAAGGGAAGGAGCCTTTAGCAGTGCCCTGGGAAGGCTCTTCAGG
+
@@@DFDEDFFHHHIGHHGHJJCHIGGGHHHIGGGGHHIJII;AFAHIHG?ECFFDFDEEDEEDBDDD2?A@DDDDCCDD>CACDCDDDDDDDDDDCCDEDD
@395
GGTTAATGAAAAACAGAGAAGCTGCTCGAGAATGTCGCAGAAAGAAGAAAGAATATGTGAAATGCCTGGAAAACCGAGTTGCAGTCCTGGAAAATCAAAAT
+
BCBFFFFFHHHHHJJJJJJJJIJJJJJJJJJJJJGIJJJJJJJJJJIIJIJJJIIJJHIIJJGJHHHHHFFFFFDDBDBBDDDDDDDDDDDDDDDDDDDDD
@396
CCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCTTAGGATATGGACAGAGTAACTACAGTT
+
CCCFFFFFHHHHGJIIJIJEHGIIICHHIIGJJIJGJJJJJIJJJJJJIJIJJGGI=BEFEEEDDDDDDBDDDDDDDDDDDDDCDDDCD:@CDDDDDCCC
@397
CCCATCTGGCGATGGTGAGGATGGGTTTTTCTCTTCCATGTTATCATCAGGTGGCTGGAGAGAGATATGTCTACAAGTTTGTGTGTGATCCAGAAGCCCTT
+
CCCFFFEBFHHDHJGFGDFGDCGIJCDDHHIIGHIJIJIJGIIIIJIIJII8EH<FHHHGEICH??EFFBEFEFECEECDDAA===ACDDDACCDD?BD?C
@398
CCTTTGGAGTGCTGCTATGGGAAATCTTTTCTCTTGGATATATGCCATACCCCAGCAAAAGCAACCAGGAAGTTCTGGAGTTTGTCACCAGTGGAGGCCGG
+
@@@DBDD?FFFHDGHIIIIGHIIIEHGGGIIGIIGIGEGHIEHFGEHGHEHIIIIIIIIG@BGGHEGED@CAHH@HDDDF>BC@AC;ACCBCCACA@@BBB
@399
GAAAAATCAAGAGGAAATGTGAAGTTGACAGTCTAGAGTTCAGAAGAGGAGTCCAAACTGGAGATATCTATTTGAGGATAATAATACCTACCTTCCCTGC
+
CCCFFFFFHHHHHJIJJJJHIJJJJJJJJJJJJJJJJJGIIJJJJJJJJJIJJJJJJJJJJJJIJJJJJJJJJJJJHHGHHFFFFFFFEEEEEEDDDDDD
@39A
CGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCT
+
CCCFFFFFHHHHHJJJJJJJJJIIJJJJJJJIIIJJJJJGIJJJJJJJJJJJJIJHJIJJJJJJJJHHHHHHFFFFDDDDDDDDDDDDDDDDDDDDDDDDD
@39B
ATTGAAAAGAGAAATAAGGTTAATGAAAAACAGAGAAGCTGCTCGAGAATGTCGCAGAAAGAAGAAAGAATATGTGAAATGCCTGGAAAACCGAGTTGC
+
BBCFFFFFHFHDHIJJJJJIHHIJJIJJJJJJJJJJJJJJJJJJJJJIJJJGIIHJIIJJJJJHHHHGFFFFFECEEEEDEDDDDDDDDDDDDDDDDDD
@39C
AAGTCAAAGAGGATATTCTTTTTGTGAAACCATCGAATAAAGGGAAGCAGGTATAGAAAGGGAGAGAGTTTTAAGAAAAGAGAAGGCTAAAAAAGGGAGA
+
(-(2()2)))9(())2)2)))))((.)))).().(1:=1))).(.<(())(())))))).(((''(((.))).)).)6((((((,7((((,(()&(((&&
@39D
CAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATAT
+
CCCFFFFFFHHHHIJJJIJJJJJJJEIJIJJJJJJJJJJJJJJJJJJIJJJJIIJJJJJIJJJIEHHHFFFFFFEEDDEDDDDDDDDDDDDDDDEDEED
@39E
CAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCC
+
CCCFFFFDHHHHHJJIHIJJJJJJFIJJJJJJIJIJIIJJHHIJJJJJJIJJJJJHHHFFFFFFEEEDBBDDDDDDDBDDDDDDDDDCCCDDDDDDDDDD
@39F
CTCAACTCATACACCGAAACCTGACCGGGCCTTCCCAGCTCACCTCCCTCCATCGCAGTCCATACCAGATAGCAGCTACCCCATGGACCACAGATTTCGCC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHHFFFDDEEEEDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDD
@39G
TGGGAGATTCCTGATGGGCAGATTACAGTGGGACAAAGAATTGGATCTGGATCATTTGGAACAGTCTACAAGGGAAAGTGGCATGGTGATGTGGCAGTGA
+
CC@FFFDFHHHHHJJJJJJJJFIIJIJJGIIJJIJJJJJJJJJJIIGGHIGIJIIIGJJIJJIJFHJJJJIHHHHFFF?BCDCEED(5>CC@CC?CDACC
@39H
GTTAGAAAAGCAAGTCCTGGGAGTGCAGAAAGGACAACAAACAGGGGGTCGTGGAGTGCTTCCTCAAGGGAAGGAGCCTTTAGCAGTGCCCTGGGAAGGCT
+
@@@DDBDDBCCBFFEHHEDCB;<F>HHBCB??;?;DC?GDDGD?BB@@4;:-99;?.;;@C>C>@@>>CBA9?<5??BACC>:ACACCCCCCBBB8AB<8(
@39I
CAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATT
+
@@@DD?DDHFFDFGHHHDEHIGGEHGJIGGFHJJIGGGHJIEFHJIIIIGGIJDGI7=DGGGECGHGGE=BDDFCEEEED=ACDDDDBDB?BDCB@A>DCD
@39J
ATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCC
+
?;<BBDDFABBFBGDEFFFAFFEHIHHHGGGGIHIDBDF<BDHFEB1?;;BA;CHE;ADFFB?CECCCCCACACCCACA@AC5@CCC:A::B>C>:@AB
@39K
CTGTTTGTCTGCCCGTCAAAAGCTTTACGATAGTACTGGAAAGAAGAGGGGAGCAGCAAGTGTAATTTGAGAAAAACTGGATTAGAAGCTGAAGAAAATGG
+
;(;@())<)).))((-(((4@).)<@))-(((()))0)):)<(<>))(.<';-'6.(6>)).:..)))6((6(-9,'(-((,((7;2((,++((5:+82(8
@39L
CTTCTCTACTCAGAAACCTTAAACATCGGCATTATCGTCCTGCGTGCAACTGTAGGAACAACCTTCATAGGCCATCTCCTCGCGGGAG
+
0(-(22)9>8):1).).(.))2)2).1((:@8:6)>(07?3:>/(75:;?7))))).)(6)(5).68)6).)(93(..(7('38'&&)
@39M
AAAAATAATAGCAGCAACAGCAATGTGAGCAAGAAGGAGCCAGCGCCCATGAAGAGCAAGCCCCCTCCCACGTATGAGTCGGAGGAAGAGGACAAGTGCA
+
@CCFDDDDFHDHAH<BHEIIEIGEHHGGGGHIIEGIC>FGGIIJJJIGBHHIIEIG9DHGHEFFDDD@CCB@5?@C@CC@@?5<BDA?BDDBDDDDCDDD
@39N
GGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACAC
+
@<@DFDFFCFHFHGDFBHHIEHIIJGGGHEEEHEABGEEGEFGCHGHGDDFCHIJHHGGDHAFIIGEGFFEFHFFFEFDDCCA?CDDDDDACDCDDCCDA
@39O
GGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACAC
+
CCCFFFFFHHHGHJJJJIIJJIJJJIJJHHIIIIJIEIIJJJJJJIJJJJJJJJJJJJGIJJJJIIJIHHHHHFFFFFDDDEDDDDDDDDDEEDDDDDDD
@39P
CCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAG
+
@@@D?DD=CADDFII9FHGCHGGCEHIEGIIECG?DG9?FHIEHBB?BGGGIIIIIIGHEEHIIHFHEFFEED@C?C;;>A=(;;@BBCCDEDC@ACDC
@39Q
CTTCTGAAGAAATAAAACAGTTAATGGGGACAGTCGAAGAACTTCAGAAGAGAAATCATAAAGACAGCCAGTTCGAAACTGATATAGTACAACGAATGGA
+
@@<DDDDEFDHAFGEFHICH>FH>AHDGG;EEDFDGGBEGHEGGGGE9DDDGGGHGBHIIIIGGCHIHCHFHHBBFFDCCC@;C;@>@C>CCCBDDBCCC
@39R
AGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCAC
+
@@@D?DADBHDA?FAGIIIFBGB8?CEHIBBFD?FGCFIGGGF2B<B8=D@FGIBEBEEC=AACA>;>@ACACCAC@BB95??BBA?<??9>CBCCCCC>C
@39S
CACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCG
+
::1=D2=;CF?B+<EF9CBE9<<AG<FAGG3:ED<<*:CA<4?D<DD@6.-7-8/)@ADD4==7...7?=;;@;)7?B>A;65>@;?1:@B>:99<?<29
@39T
CTGCACAGGGCATGGATTACTTACACGCCAAGTCAATCATCCACAGAGACCTCAAGAGTAATAATATATTTCTTCATGAAGACCTCACAGTAAAAATAGGT
+
@?@AFDBDFFFDFEHECHDIIICHCHHIEGGIEHHGGHIGIGIHECDGHHIGEIHIFH@@D7@GGC@CCCEHHHCE>CEEFFEECECDCCCDCCCDDDAC,
@39U
CACAGATTTCGCCGCCAGCTTTCTGAACCCTGTAACTCCTTTCCTCCTTTGCCGACGATGCCAAGGGAAGGACGTCCTATGTACCAACGCCAGATGTCTG
+
@@<DDFDDDHBHFEGGG<EHEIGHCHIIIJJGA?GCD<DGGEBGDGHGHIDB@A@BEDDCCC@CBDDA?@BDB?;@BDDCD>CD@@CBBBD<@?CCCCCD
@39V
CTTGAAGACATGTTGAAAATACATACTCCTGTTAGCCAAGAAGAAAGATTGATTTTCTTAGACTCCATTAAGTCCAAATCCAAAGACTCTGTGTGGGAAA
+
CCCFFFFFHHHGHIJJJJJJJIJJIIJJIIIJJJJIIJJJJIJGIJJIJIJJJJJJJJIJGGIGGGIJIIJJHIIGIGGJHGHHHFFEDFEEE@ADDDDD
@39W
CCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCT
+
???DDD8D?D;DD1CE)<CFE>A@DDE?B?@??:??;DD:04@=@(=;A;?ACD;>@3?3>;;@A25>(5',,5(55>:>A>(9<18<>9<3:>:A>>38(
@39X
ATAAATCCAACTACAGTGAAAATGAAAAGTTCTGTCTTTGATGAAGACAAAACTTTTGTAGCAGAAACATTGGAAATGGGTGAGGTTGTTGAAAAGGATAC
+
CCCFFFFFHHFHGIIEGHBHIGIGGIGBGIIIGIGGHJJJHIJIJGIJJJJJJIJIIGDGGIHIJJJIIJEGJGIJFGDF?BABECECAAEDDDDCBBCAC
@39Y
CTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACC
+
@CCFDAFFHHGHGIIIFEHIIIEIIGGGHHIIHIIIGHHICGHEGEEEIGGIIGIF9AABFDDEFEEDDC7AC@CDDCDDD?(9?<@@@>@CC@:@>:ACC
@39Z
CCTCCCTCCATCGCAGTCCATACCAGATAGCAGCTACCCCATGGACCACAGATTTCGCCGCCAGCTTTCTGAACCCTGTAACTCCTTTCCTCCTTTGCCG
+
@@@DFFDFGHGGFIBGABFEHIIIIIIIIG@EHICHHGIIHCDGDGHGIHEEGBHGII@EH><ACCECDCCCCDDDDC@C>CC>CCC@AC@CDCDDCDDB
@3A0
AAAAATTCGATGGAGACATCAAACAAGAGCCAGGAATGTATCGGGAAGGACCCACATACCAACGGCGAGGATCACTTCAGCTCTGGCAGTTTTTGGTAGCT
+
???DB?BDCDDB:AAEDDE::E:AE32CCEDE@BDDEE0?B>D6DADD1BDADDD@.=7=ACCD<?6==8;AA>AAAAA>AAA3:>>>?9:AA>0;(44>(
@3A1
TTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGC
+
?@;B?:AADFDBD?FFBFEEHECH@GGG9BEF9?E?CFHGHB6B?@GHIE@@;C@FEGDDHHEHAC=A@7?CEC@>C>C>ABB;(;?5::;>:<BCBB?B<
@3A2
GGATTTTTCAAAAGCAGATTCAGGTGTTCATTTATGTGTTATTGATGACTCCAATGAGCATATGCTTACTGTATGGGACTGGCAGAGGAAAGCAAAAGG
+
CCCFFFFFHHHHHJJJJIJJJJJJFGHIJJIJJJIIHIGHIIJJJJJJJJJJJJJJHJJJGJJJJJJJJIJHIJJJJJJJJHGHHFFFDEEEEDDDDDD
@3A3
CCTATGGGCAGACCGCCTATGCAATTTCTTATGGACAGCCTTCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTAT
+
CCCFFFFFGHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJIJJJJJJJJIJHHHHHFFDDDDBDDDDDDDDDDDDDDDDDDDDDDD9BC
@3A4
CAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGT
+
CCCFFFFFHHHHHJHJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJHHHHHFFDDEEDDDDDDDACCDDDDDDEEDDDDDDDDDDDDDDDD
@3A5
TATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCC
+
@@@D=DDDGFAHHIIIIIIGHEGHIIGCHCFHFIIIEHEHIGIIG<D>EEFGEHGGFDC@EACE=EEEBBCDDEA>CECEDA5=C?9?ACCDDDC?@DADB
@3A6
CCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGT
+
CCCFFFFFGFHHGEIEGIJJIJJIIJJJJJJGHGIIHGIJJIIIJIJJJJGJIGGIJIJGJHGJGHHFFDCCDC@ACDDDEEEDDDDDDDDDDDDDDDDC
@3A7
CCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTC
+
CCCFFFFFHHHHHJJJEHIIJJJJJJJEGIJJJJJJJJJJJJIJJIJJJJJJJJJJJJJJJJJJJHHHFFFFDEEEEEEDDDDDDDDDDDDDDDEDDDDDD
@3A8
ATGGAACAAGAAACACAAAGAAAGTTAGAACAACTCCGGGCAGAGCTGGATGAGATGTATGGGCAGCAGATAGTGCAAATGAAACAAGAATTAATAAGAC
+
@@@DDD??F;CD?BFFGDEE?FE?AEH@?GGGCF>FGD6?@FAFCDDFAE@@F7CFFEFIFFFFEB?DDB>@C6@@BBBBBAAB>AB@@BBB@BADB>:A
@3A9
CAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGC
+
CCCFFFFFHHHHHJJJJJJJJIIJJGIIJJIJIJJJIJFHIJJJJJIIJ@GFHHHHHHFFFFFFDDDEDDDDDDDFDDDDDDDDDDDDDDDDDDDDDDDD
@3AA
CTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGC
+
@@@FFFFFFHHFFGCGIIJGGIJIIF@FG@GCDDHGHGCHIJEHIJC><FHGEGCGIJHGHJIEIEHHHFDDBDDEEA@CDEDDDDDDABDDDDDDBCDD
@3AB
CCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTAT
+
C@CFFFDDHHFFFEIIJIJJIIGGGFCHGIJEGIEICGIGCCGCFHGGJGG@HIGDCEFHEGIICGGHHHHGFEFFCCAAAEBCD@CCD?CDDABDDBBBD
@3AC
CAAAAGATATGCTTACAAATTTGACTTCCACGGCATTGCCCAGGCTCTGCAGCCACATCCGACCGAGTCGTCCATGTACAAGTACCCTTCTGACATCTCCT
+
CCCFFFFFHHHGHJJIIJJJJJJJJJJJJJJJJJJJJIJJJJJJJIJJJJJJJJJJJJJJIJIHFDD@DDBDDDFDDEEEDDCCDDDDDDDDEDDDDDDDD
@3AD
AGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCC
+
@CCFFFFFHFHDHJJJIJIJHHIEFIJJIGGIJIJDIIGEIIIGGIJJIJGIIHFIIHIJEGCHIJIGHHHGHFEDDDEDDDDDCDDDDDCDCDDDDDDDD
@3AE
GGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCAC
+
CCCFFFFFHHHHHJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJIJJJIHHFFDDDDDDEDDDDDDDDDDDDDDDDDDDDDDD
@3AF
GGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCC
+
=;@DDBDBFAHBHEIBGIHIIBHGGIDIIIHGGGGBIIGDGI;CFGGGIEIEHHE>E>C@C@CECADCCC?CCCCCCCCCCCCCBBBBBB?ACC@BB@BB?
@3AG
GTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAAC
+
C@BFFFFFHHFHHJJJJJGIJJJJJIJJJJJJJJJJIJJJJJJJIJJJJJJJJGGIJIJJIJJHHHHHEFFFFFDEEDDACDDCDCDDDDEDEDDDDDD
@3AH
CGAGGATACCTGTCTCCAGATCTCAGTAAGGTACGGAGTAACTGTCCAAAAGCCATGAAGAGATTAATGGCAGAGTGCCTCAAAAAGAAAAGAGATGAG
+
????D1++ADDCAEE@E?C3AE>ECEA@CF32@CEA1:)00?4B0?DADAD>D83=B=BC:A7@@AECECA;=56.77;;AAAAA@>?;5(:=?9:>>:
@3AI
CAGCAAAGGAAGAAATTGCTCAAAGATGCCATGAACTGGATATGCAGGTTGCAGCATTGCAGGAAGAGAAAAGTAGTTTGTTGGCAG
+
?;;D12BB8DDDDDB::C?F?43<C<?F>C?@CEEFADE>9D?<4:D;009)9?D;48B8=BC;=6AC37==;ACA37??(?A@6>@
@3AJ
CGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCA
+
@BBFFDFFFHHHHJGJJJJJJJJJIJJJJJJJIJJJJJJJJJJJJIJHJJJJJJJHHHHHFDDDDDDDDDDDDDDFDDEDDDDDDBDDDDDDDDDDDDD
@3AK
CGGGAAGGACCCACATACCAACGGCGAGGATCACTTCAGCTCTGGCAGTTTTTGGTAGCTCTTCTGGATGACCCTTCAAATTCTCATTTTATTGCCTGGAC
+
@@CFDFFFDHBFFHBHGGGDIIIDAHGGIEGHIIFGIIGGGGEHHHHBBDB@DDB;@CCCCCCD>:@>CD>A@BCCDDDDDDCCDA@CDEEDD<>CCDBBB
@3AL
TCAACCTCAATCTAGCACAGGGGGTTACAACCACCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGC
+
CCCFFFFFHHGHHIIIJJIJJIIJCGIIIJJIJJJJJJJIIIJJJJJIIHHHHHHFF>CFEEEEEECCDDDDDDDDDADDDCDDD<BDDDDDDDDDDDDDD
@3AM
CCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCT
+
CCCFFFFFHHHGHJJIJJJJJJJJHJIIJ?FHIGIJJGI2BFHIJJJJJJJJJIJIJJJJJJIJJHHHGHHFFFFDDDBDDDDDDDDDDDCEDDDDDDCDC
@3AN
CACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACC
+
@@@DFFDBHHHHFHIHIIJJJG@AFHIDGIGHHGGHIIEGGEHBGCHFFGHGGGD==CCBDBECCEC@CDC>CCCADDDC@@BDDCDCDCC>:@CDDDDD
@3AO
CTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTTATGGGC
+
@@@FFFADHBHHHIGIJICFHIEIIIIJIJJGGHIIIJJJJJJIJJJJJJJJJJJIIJIIJJHHHHFFDDDDBDBDDDDBB>CDCCDDDD390<CDDDDDB
@3AP
TTACAACTTAAAACAGAATTGTTAGAAAAACAGATGAAGGAAAAAGAGAATGATCTTCAAGAAAAATTTGCACAACTTGAAGCAGAGAATAGCATTCTTA
+
@<@D?DBDFFFBFGHIGHGIIHDFH>EHHHIIIFHGDCFDDHGGIGEIIIIHGIIIIGIHIIIIIIIGGGGIAEH;EFDFFDDCEECDDCDDCCCACDDC
@3AQ
GTCTGAGACTCCTGCTCAGTGTAGCATTAAGCAGGAACGAATTTCATATACACCTCCAGAGAGCCCAGTGCCGAGTTACGCTTCCTCGACGCCACTTCATG
+
B@@FFFFFGHHFHJJIJJJGGHHIJJJJJJJFJJJIIFGICHGHIJJJJJJIJJIIJIJIJIIJIIJJCCCEHDDDDEEDDDBDCDCDDDDDDDDCCDDDD
@3AR
GCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGAC
+
@CCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJHHHHHFFFFFEEEEDDDDDDDDDDDDDDDEEEEDDD
@3AS
GTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCC
+
CCCFFFFFGHHHHIJFGIEGIIFIJJIJJJJIJGIHIIJJJJAHHIJIHHHHHHHFFFFFFEDDEDDDDDDDDDDDDDDDDDDDDCDDEDDDDDDDDDD
@3AT
CTGGAGGAGGGAAAGACAGAAAAATAATTCTGTGGGATCATGATCTGAATCCTGAAAGAG
+
B@BFDFFDHHHHHJJJJJJJJJJJJJJJJIJIIJJJIJJJJJJJJJJJJJJJJJJJJJJI
@3AU
CGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCG
+
CCCFFFDFHHHHHJJJJIIJHIJHJJJIJJIIIJJJJIIJJJJJJHHHFFFFEEEEEEEDDDEDDDDDDDDDDDDDDDDDDDDDDDDDDDCCDEDDDDDDD
@3AV
GTTACAAGAATTTGAAGCTGCCATTAAACAAAGAGATGGCATTATAACCCAGCTCACTGCTAATTTACAACAAGCAAGAAGAGAAAAGGATGAGACAATG
+
+=?7BDDDFF?2CAAEGFEFCFIBHHEHEFGEFGFEEFCGIFCGF9B?BFEFFF8BFF<FDB)=FF>FFGDEC@?=CEE>D@DC<;;>@,;;;@5@9@>B
@3AW
CCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACT
+
CCCFFFFFGHHHGJIJJJJJJJJJJGGIIIJJJJJJJJJJJIJJJJJJJJJJIIJJIJIJJIIJIGIJHHHHHHFFFFFEEEEEDDDDDDDDDDDDDDDDC
@3AX
CGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCC
+
CCCFFFFFHDHHHBHIHHIFHHGIJJJIJJJJJIJJIJJIJJJHJIJJHHHHHHFFFFFFEECDDDDDDDDDDDDBDDDDDDDDDD>@CEDDDDCDDBDD
@3AY
TAGAGAGCTAGAAATCATTATTAACCACAACAGGGCAGAAAATGTACAGTCATGTGATACTCAAGTAAGCTCTTTATTAGATGGAGTTGTGACTATGACA
+
B@@FDDDFHHHGFIJJJJIIJGIJGIJJJJJJJJJIJJJJJIJFBGIIJFGEGIIIIJJIJIIGGIIIJGGGIIJFFHHEFHFFEFDEDEDEEDDDDCDD
@3AZ
CCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGAGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTAT
+
@<=AB:=DFF;?DFE;ABBGEIDFEDBBF@GEEG*0?DFCFBAF:AFEBE>EFDDDDDCCCC>@;ABDBA@>?BBBB@@B<BB@A>@A??<8<<@B9@@B>
@3B0
CTCCTGTCTCTGCTGGAAATGATGCCTATGTTGACCTTGATCGTCAGCTGAAGAAAAATACAGAGGAACTAAATGAAGCTTTGTCAGCAAAGGAAGAAATT
+
1?8BDADDFF<CD<C:EF9F9FB>?CFHF@FH9CDFFC4*?@)??GEEF@<DFEFII(..=F>)8((86;@DEEEFAE;?BDDB@BC(;;6>9=;==A95:
@3B1
CCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAAC
+
@@@DD>DDDHHDCFCGIBFEIGI@BHIDHGEG@C?CDDGBFFDFFEGGGHHGGDEHIII@CFHGEEBEDEEECDCECDC>CCCA@CACC:@C@CCCBCC?
@3B2
CTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJIJIJJJJIJJHHHHFFFDFFEEEEEEEDDDDDDDDDDDDDDDDDD
@3B3
AAAAACTCAAGGAAGAACTAGGACTAATTTTAGAAGAAAAGTGTGCTCTACAGAGACAGCTTGAAGACCTTGTTGAAGAATTGAGCTTTTCAAGGGAAC
+
CCCFFFFFHHHHHIJGIJIJJJJJJJJJJJIIIJJJJJJJJDHHHIIJJJJJJIIIIJJJIJJJJIJJJIJJHHGHHHFFFFFFEEEEEEDDDDDDDDD
@3B4
AAGGCTTCCTGGCTCATCCCAGCAGAACAGAAGGCTGTATGTTTGAAAAGGGCCCCAGGCAGTTTTATGATGACACCTGTGTTGTCCCAGAAAAATTCGAT
+
CCCFFFEFFHHHFIGEGHIJGIIJJJJIGBDEDGIJFB>GHFHGIJGIJJJJIJIIEEGHEC=CEHEHFC>@@?CEC>@;>>?B?ACDDDDDDCBDCCDD@
@3B5
CCCTAATCCAGGCCTTTGAAAAAATGACGCATGGAAACCTGAATAAGGTCCTCAGGGCCAATGCGCCAGATGTCATGACCCATGAGGATGGACAGCCCTGC
+
;<<@5.2@)):)2()))))3)2(2@)))-:?(0())....<>19.6.)//<)))):(=3(().),',''.(--((((((,8((5((7((5+(+((+8((((
@3B6
GCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATAC
+
?@@D?DDD?<FHHGBDG=GG9FHIEGIGGH??F?BBG>GHGIEF;FCCHIIGGIIHH=AHD@77@;CCCCC?3>C@@:@@@BBBBB<>4@@DC>AC>@CAC
@3B7
CGCTATTACTATGAGAAAGGAATTATGCAAAAGGTGGCTGGAGAGAGATATGTCTACAAGTTTGTGTGTGATCCAGAAGCCCTTTTCTCCATGGCCTTTCC
+
CCCFFFFFHHHHHJJJJJJJIJIJJJJJJJJJJJGHIIIJJHIIJIIHGIIIJJJJJJJJIIIIFHGGGIHHHHHHHFFFFDEEEECDDDDDDDDDDDDDD
@3B8
GACAAAAATAATTCTCCACAATATTCACTTCTATAGCATAATTCAGTACAGAATTAATCATAAGATTCTTACTGTAAAAGAAAAAAGGACATCCTAATAAT
+
:11?A7+2?A+<?27<?A+?A3+,<3<2++22+:*:1:<**1**1**0?A000***0=*/****9=<)))//.)))/)).;(.>2,',.(.6((((-(5;(
@3B9
GGAACCTCCTCCTAAAAAGACGAAGAAAAATAATAGCAGCAACAGCAATGTGAGCAAGAAGGAGCCAGCGCCCATGAAGAGCAAGCCCCCTCCCACGTATG
+
=<=AA;AA?<++<7<@<@?A;A8A;ABBBBBBBBBBABA=ABBAABBAB>>A>A;ABB;>AAAA9=@@@@@===3;;??===?==9;;;9;59<<=;;<=;
@3BA
GCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTAT
+
C@CFFFFFHHHHHIJJJIJGHIJJJJEGHIJJJJJJJJIIIJJJJJJGIJJJIJJIGIJIIJJIIIJIHHHHHHFFFFFDEEDECDDDDDDDDDDDCDDDD
@3BB
CAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJIJJJJJJJJJJJJJFHIIJJIJJHIJJJJHHHFFBDFFEDEDBDDDDDDDDDDDDDDDDDDCDDDDDDDDDDDD
@3BC
ATCCGGTTCTCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACAAGTT
+
==1<7A00<>C>C7?<+23<@@??:3=8;7*:=:1))=A*==A=/=4.>7><;)=56A>=B;>AAA@;<>@@(.5;;?=;35;>:>9>=:(9()5.&02:8
@3BD
CCCCGATGAGGTGGCCAGGCGCTGGGGCGAGCGGAAAAGCAAGCCCAACATGAATTACGACAAGCTGAGCCGGGCCCTCCGTTATTACTATGATAAAAAC
+
CCCFFFFFHHHDFJJJJJJJJJJJJJJJJJJJHFFDDDDDDDDDDDDDDDDDDDEEDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDEDDEEDDEEDDDDD
@3BE
TGATGACACCTGTGTTGTCCCAGAAAAATTCGATGGAGACATCAAACAAGAGCCAGGAATGTATCGGGAAGGACCCACATACCAACGGCGAGGATCACTTC
+
@@CDDFFAHHHHDEGHHIJJIJIHGHGBEHFFDHIJJJGIFIGEGGAHIIJHIGGBCCEGH;C>EHGFF/?;;6;?A@@C@CDCC88@D>BBDB9>BC>CC
@3BF
GGCTCATCCCAGCAGAACAGAAGGCTGTATGTTTGAAAAGGGCCCCAGGCAGTTTTATGATGACACCTGTGTTGTCCCAGAAAAATTCGATGGAGACATC
+
@@CFFFFFGHHHHJJIJJJIJIJJJJJIJJJIJJJJJJJJIJJJIJJJIJJJHIIIIJJJJIJJJHHHHHFFFFFEDDEEDDDDDDDDBDCDDDDDDDDD
@3BG
GAGCTCCAGGAGCAGCTCAAAGCCGTGCACGAGCAGCTTGCAGCCCTCTCTCAGCCCCAGCAGAACAAACCAAAGAAAAAAGGAGAAAGACAAGAAGGAA
+
<@@DDADFFHHAHIGIBGGBHGIGIDGECGIIGF@F@GIHIIGBCGICEEHGIGIGFEFDFFBBC>CEBCCBBCCC?C<?B>BBBBCC>?CCCB?CCBBC
@3BH
GGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCC
+
BCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJHIJJJJIJJJJJJJJJJJJJHIJJJJJJIHHHHFFFFDDEDEDDDDDDDDDDDDDDDDDDDDDD
@3BI
CTCAAATAAAGAAGAAATACNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN
+
<<<??@@???@??>??@@??#################################################################################
@3BJ
AGCAGATGTGCAGCACATTAAGAGGAGAGACATCGTGCTGAAGCGAGAACTGGGTGAGGGAGCCTTTGGAAAGGGCTTCCTGGCCGAGTGCTACAACCTC
+
?<?DADDADDD??E:2AC?F:443+3232:C9CE=D;?DAEDD9@D?6;)==>@78==>5A:9?7?AAA;A;?9(5;<5::>9?=2-)(2(4>AAA4<99
@3BK
TACCAACGCCAGATGTCTGAGCCAAACATCCCCTTCCCACCACAAGGCTTTAAGCAGGAGTACCACGACCCAGTGTATGAACACAACACCATGGTTGGC
+
CCCFFFFFHHHHHJJJIIJJJJJJJJJJJJJJJIJJJJJIGIJJJJJJJJJJJJJJJJJHHHHHFFFDDDDDDCCCFFEDEDDDDDDBDDDDDDCCDDD
@3BL
AGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCC
+
@@@FFFFFHHHFHIGHHJJJJJJJJJIJJJJJJJJJJJHIIJJJJJJJJJHHHHHHFFFFFEEEEEDDDDDDDBDDDDDDDCDDEDDDDDDDDDDDDDDD
@3BM
TGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCT
+
CCCFFFFFHHDGHJJJJIJJJJJJJJJJJIJJJJJIJIJJJJJJJJJJIGHIIJJJJJJJJJJJJJJJHHHHHHFFFFFFEEEEEDDDDDDDDDDDDDDDD
@3BN
GAAAACACTTGGTAGACGGGACTCGAGTGATGATTGGGAGATTCCTGATGGGCAGATTACAGTGGGACAAAGAATTGGATCTGGATCATTTGGAACAGTCT
+
CCCFFFFFHHHHHHJJJJIJJJJJJIJCDBGHIIJJJJIIHIJJJIJIGIIIIJJIJIJJIJAEHHED?DFEDEDEEDCDDCDDCDDDDEEECDDCDCDD@
@3BO
AGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCC
+
CC@FFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJIJJHIIJJJIJJJJJIJJJJIJIJJJJHHHHFFFDDDDDDDDDEDEEEEFDDDDDDDDDDDDD
@3BP
CTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAA
+
?@@?+BDD?DF?<FDGEE9AC@E9F9C9EDG3?C9?FA?BF393?B@FIB8B=CDCDF=@1=@==?/=3>(;>>>A(35??@?9(,::;>:::4+:@:A<
@3BQ
GTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGC
+
@@@FFDFFHHFHFJJJIJIHGGJIICGIIIJJJJIIJJJIGIJJIIHIIIDIFHECHF;@BCFEEEECEDCCDDDDDD:@CC@ABDD?B@DDDDDDDDD
@3BR
GGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGC
+
BC@DFFFFHHHHHIJJJJJJJJJJJJHJJJJJJJJIJJJJJJJJJJJJJJJJJJJIJJJJJJHHHHHFFFFEEEEEDDDEDEEDEDDDDDDDDDDDDDD
@3BS
TGGAGACTCAGGTGGAGTCATGCTAATATGGAGCAAAACTACTGTAGAGCCCACACCTGGGAAAGGACCTAAAGCTGTATATCAAATCAGCAAAAAAATC
+
7((282291@<<.48?>94)8>>>)9=@?))2()1;9===)):9)0))6)((7<56;<)8((.=((6<>537;8)...6==1:8;>>0977(;0(555((
@3BT
AATTTGTGCAGTGTTTAGCATTCTTGGGGAATGGAGATGTTCTTACTGGAGACTCAGGTGGAGTCATGCTTATATGGAGCAAAACTACTGTAGAGCCCAC
+
@@BFFFDDHHGHFJJIGGIJJIIIIJJIGEGHGEIIHIEFHIJIIJJGAHGGIGGHIEBFHCG@CGGGGIIIGAHFHEHFFFFF@CACEDBDCDCDBDDD
@3BU
CATCAACAAGCTCCCCGGCGAGAAGCTGGGCCGCGTGGTGCACATCATCCAGTCACGGGAGCCCTCCCTGAAGAATTCCAACCCCGACGAGATTGAAATCG
+
CCCFFFFFHGHGHJJJJJJJJJIJJIHIGIGIIIHFFDCDDDDDDDDDDDDDCCDDDDDBBDDDDDDDDDDDDDDDDDDEDDDDDDDDDDDDDDDDDDDDD
@3BV
CGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGG
+
BB?DFFFDHHHGGIIJJGIHHIHJJJIEHGGCGIICHGGGIGIIGCGHGGGGGFGHGGIJIJIHHHHCBB@;A;ACACEDDDCCCCDDDDCDCCDDDDDDD
@3BW
CCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCT
+
CCCFFFFFDFFHHJJIJJJJJIJHGIJHHIGIJJJJJIIJJJJJIIJDGIIJCHIAHIGIJJJJJJHHHHHFFFFFEEEEEEDDDDDDDDDDDDDDDDDD
@3BX
TTAATGGCAGAGTGCCTCAAAAAGAAAAGAGATGAGAGACCACTCTTTCCCCAAATTCTCGCCTCTATTGAGCTGCTGGCCCGCTCATTGCCAAAAATTC
+
CCCFFFFFHHHHFHIJJJJJJJJJJJJJJJJJJJIIIJJJJJJJJJJJJJJJJJJJJJIJJJJJHHHHHFFFFFEECEEDDDBDBDDDEDDDDDDDDDDD
@3BY
TCTCAAAAGGAAAAACTCAAGGAAGAACTAGGACTAATTTTAGAAGAAAAGTGTGCTCTACAGAGACAGCTTGAAGACCTTGTTGAAGAATTGAGCTTTTC
+
???DD>;=2+22<AA@E??;@+<CDAFEC@E;EDDEI@EDEID3B>DECDDEEDBBBB8B>C=)8=ADC=CDDDD>D>;@A@A>AAAA;>AAAAAAAAAAA
@3BZ
CAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTC
+
??@:?BDACFD???8CEEC;FE??CF??BBDDBFCCBFDEDF?HGB@HEHHGIGGHIIEGFHIIA?AA?DDECCCC@AAA?ACCCACCCCCC@>><C>??
@3C0
GGAGTGGGCATATGGTTATCGAGGAAAGGACTGTAGAGCTAATGTTTACCTTCTTCCGACCGGGGAAATAGTTTATTTCATTGCATCAGTAGTAGTACTAT
+
:;+?277A<CB@C=C,2<@BAC=AABAA>>AB=BBBB::AB==A=ABABBBBABBA><<<A:=6=:==??=;>?:>?>9(9>?:=??=?:??+3:??????
@3C1
GCTACTCCCACCAAAAGCATAAAACGACCATCACCAGCTGAAAAGTCACATAATTCTTGGGAAAATTCAGATGATAGCCGTAATAAATTGTCGAAAATACC
+
8=1D?3?+2AF:;F;F?G;:<<AAACE>AFEI<FG@@B?<DBFFCBDFCFFF=7==AFEF?67?CE)))..?@:;@6@BC9>@;@BA>>3(,2???<+44@
@3C2
TGAAATGGAACAAGATAAAAAAGTAGAAAACTCAAATAAAGAAGAAATACAGGAAAAGGAGACAATCATTGAAGAATTAAACACAAAAATAATAGAAGA
+
CCBFFFFFHHHGGJIJJJJJJJIFHIJJJJJJJIJJJJJJIIJIJJJJJJIJJJJJJJJGIIIIJHHHHHHGFFFFFEEEECEABDDDD?CDEEDDDDD
@3C3
CATTACATCCCGAATCGCGGAAGCAGTTTTGAAACCCAGTGGGGCGGGGGAGGGGGGATCGGGATTATCGACGGGAAAAGGCAGCGGAAACATATTGGCGG
+
(08((98).)<((((2(--<3(3<))0..0((09:(-5()))(5',,&&)&05&&&&&)+&&&))8/+(((&&&&&&+(((((((&)&&&((+(((+(+0&
@3C4
GTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAAC
+
B@@FFFFFHHFFHIJJJJHIJJJJIJJJFIJJJJIJJJJJJJJJJJIJJJJJJJJJIJIJJJIHHHHHEFFFFFDEEDDDDDDDDCCEDEEDEDDDDDD
@3C5
ATTAAAACATGAAGCAGAAGTTACAAATTACAAGATAAAACTTGAAATGTTAGAAAAAGAAAAGAATGCTGTGTTAGACAGAATGGCTGAATCACAAGA
+
@@@DD;DDBAFFDF>F:CFG?:AAEEFIEHIIIEE@DDFFFEEFAFAFGAFFIEGAFFFFFFCEFFA;FCE777=CAA7?EBB@@@BA@BAA;@@ABBB
@3C6
AAGAAAACTCTTGAGCTAAAGGATAAATTAACAACTGCTGATAAATTACTAGGAGAATTACAAGAACAGATTGTGCAAAAGAACCAAGAAATAAAAAACAT
+
@CCFFFFFGDADD<FBFGEIEECGFGGIDHHIGGGIGGIIIGIHIIEHIIIGGGGHIIEIIIC@GH>H>FIHG=@CGHGHHHFFFFD@ECDCDCDCDDB?C
@3C7
CAAGATAAAACTTGAAATGTTAGAAAAAGAAAAGAATGCTGTGTTAGACAGAATGGCTGAATCACAAGAAGCTGAATTAGAGAGGCTGAGAACACAGCTTC
+
CC@FFFFFHHGFHIBHHJJJHIIJIJJJJJIIJGIIIJIJEDDGGGGIJIJIJGHJJIGIJIIJJJIIEHCGGFFHHHHFFF?BCDDBDBDDDDDBDDDDC
@3C8
AAGGGAAGGACGTCCTATGTACCAACGCCAGATGTCTGAGCCAAACATCCCCTTCCCACCACAAGGCTTTAAGCAGGAGTACCACGACCCAGTGTATGAAC
+
C@CFFFFFHHHHFGIJIIJHHIJJJJJJJJJGIJIGJJJJIJIIJJIIIJIIJJJJIFHHHFFFFDDEEEDDCDDDDDD<ACDDDDDDDDDDCDCDDDDED
@3C9
GCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCC
+
CCCFFFFFHHHHHJIIJJJJJJJJJJJJJHJJJJJJJJJJIJJJJJJJJJJJIJHHHHHFFFFFFEDEEEEDDDDDDDDDDDDDDDDDDDDDDDDDBDDD
@3CA
CTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTAT
+
CCCFFFFFHHHHHJJJJJJJJJJJJIJJJJJJJJJJJJJJJHIIJJIJJJJHCHHHHFFFFFFEEEEDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDD
@3CB
AGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCAT
+
++1AAA70?AA?7<?)?55=ABABBA>A=A4=A=>A17>8=>B9>AA>>>A99ABAAAAA;?9>;>55;;;??>=9===>=95=;9?7;?===?;;88<<3
@3CC
CAAACCCAAGCCCTGTCTTCCAAAGCGACCAATACCAGGCTACATCCCAGGCTGTGGTTACAGAGAAAACAGGCCATGTGAGCCACCGCTGGCAGGGCGG
+
;(-=((((2.->82()22)9)9>8))(-1(7=))0)))((.).)//<9)6(6(;<.))-=8>1.)).(.((.(,,(72,,5;55;((&&)&&(52&)(&5
@3CD
CTTGAGTCACGAGTTCAGCAACAAGAAGATGAAATCACTGTGCTAAAGGCGGCTTTGGCTGATGTTTGAGGCGTCTTGCAATCTCTGAAGATCATGTGGCC
+
CCCFFFFFHHHHGIIJJJJJJJJJJIJJGIJJJIJJJJJJIJJJJJJIJIJJIFHHHFFFFFCEEEEDDDDDDDDDDDDDDDDDCDDCDA@CDDDDEDDDD
@3CE
CCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTG
+
@CCBDFFDHHHGHHGHIIIIIJJJJJJIEFHGIIJJJJJHIJJJGJJIIIJJIJIEGGGIGGGEGHHEHHCFDDFDD?B=ABCBDDCCCDCCC?CDDC@CC
@3CF
GAAATCTTTTCTCTTGGATATATGCCATACCCCAGCAAAAGCAACCAGGAAGTTCTGGAGTTTGTCACCAGTGGAGGCCGGATGGACCCACCCAAGAACTG
+
@;?DDDDDF>:C<<F@FEFIBDF@E9C@BFEI=C?DGGB9?BF3B3DF6?BF8B9=).B;=;C=@=D:=76).=;=;5?<3'98<>:589?B>B@BBBB>A
@3CG
CATCCCCTTCCCACCACAAGGCTTTAAGCAGGAGTACCACGACCCAGTGTATGAACACAACACCATGGTTGGCAGTGCGGCCAGCCAAAGCTTTCCCCCTC
+
?<8A=A:B;DFFFBFFIIEF?EDEFF<CFFGEED?DFFGIGIFFF?C@FFCFE>DF>DEECE=BDBDA>@@8@>=(5@??=BB??@<<9?B::ABB@B@9@
@3CH
AGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACC
+
:;14:3BD<DB1A3AEEE+3+??@@EEEE><D*9*9B:):0*9B?36??CBC(7AC>D:AA:74@C)7?A;;(.6;;@>=3>>33;AA9A>A>:<?<9>(<
@3CI
CAGCTGCAGACTTACTACAAGCCAAACAACAGATCCTCACTCATCAACAGCAGCTTGAAGAACAAGACCACTTATTAGAAGATTATCAGAAAAAGAAAGA
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHHHFFFFFFFE>CEEEDEEDDDDDDDDDDD
@3CJ
AACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACT
+
@@@DDDDDDBHFHIIIIID<EEHHHIGHGIIHIIGGIGEHIGIIIIFFHIIGIIGIGGGIGIEGIIIHHFFEEEEE>BCCCADECCCCCACC?<ABBB@
@3CK
GGTTCATCCTGCTGGAGCTCATGGCGGGGGGGGACCCCAAAGGCCTCCCCCGCCAGAACCCCCCCCGGCCGGGGCCGGCCTCCCCCCCGGGCGCGCGGGGG
+
@@@D=D;DF8?D3+AA<AFCGF<BE@?0'96&))&((((((+++(+22(57&&&))(((2&057&0&&)5&&&&&&&&&0&+8(09>&))&&&&&&&&)&&
@3CL
CAGTAGTAGTACTATTTAATTATGAGGAGAGAACTCAGCGACACTACCTGGGCCATACAGACTGTGTGAAATGCCTTGCTATACATCCTGACAAAATTAGG
+
@@@DDFDDFHHHHIIGIIGIIJIIEHIEIHEGHIEGHIFHG>DHHIGCHHIIJGDHGIGGGGIGCAAEHGHDFFFFFEEEDEDCCDCDDDCCCDDDDDCCD
@3CM
TGGATGCTGTAGGCTTGGAGCTGCCTGTACAAATAGAGGAGGTCATAGAGAGCTTCCAAGTTGAGAAGTGTGTAACTGAGTATCAGGAAGGCTGCCAGGG
+
@@@DD>DDBABFBHBBCEB?FDEHGGIIGFGGI<FBFHH;D?FH<?9BFG<F?FG=BFGG@@;786@77=@;(7AAE;3)7;@66;66(;?;(,5,,55;
@3CN
AAGGAAAGTGGAAAAAACCTGAGAACTTCCTGATCTCTCTCGCTGTGAGACATGTCTGAGACTCCTGCTCAGTGTAGCATTAAGCAGGAACGAATTTCAT
+
CCCFFFFFHHHHHJJJIJJJJJJJJJJJJJJIJJJJIJJJJIJJIGGGIJIJJJHIJJJGIIJJJJFHHHHFFFFFFFEEEEEEEDDDDDDDDDDDDDEE
@3CO
CCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGT
+
BCCFFDEFHHHHGJJIJJJJFGIIJJIJJIJJJJJJIIJJJJIJIIJJJJIJHEHHFHFFFFFFEEEEEDDDD@CCDDDDDDDDDDDDDDDCDDDDCDDDC
@3CP
GGGAAGGACGTCCTATGTACCAACGCCAGATGTCTGAGCCAAACATCCCCTTCCCACCACAAGGCTTTAAGCAGGAGTACCACGACCCAGTGTATGAACAC
+
CCCFFFFFHHHHHJJJJIIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHHFFFFEEDEEECDDDDDDDDDDDDDDDDDDCCDEEEDEDDD
@3CQ
CAAAGACCCTGATGTGGTGGCCCGGCTGTGGGGCGTTCGCAAGTGCAAGCCCCAGATGAATTACGACAAGCTGAGCCGGGCCCTGCGCTATTACTATAAA
+
CCCFDDAEHDDF?GFHIDC;CEEFHF@ADFEGBHIBEHEBBCC36>CC@BBBBCC?C@>C>AC:887;BB<CC:8@CBBB>B<BBABBBB<CD4:CDCC(
@3CR
GATTTCGCCGCCAGCTTTCTGAACCCTGTAACTCCTTTCCTCCTTTGCCGACGATGCCAAGGGAAGGACGTCCTATGTACCAACGCCAGATGTCTGAGCC
+
@?@DDDFFFHDDDF=BEGGI>BFGIIGEHIGIIGGIGCH<FHHIIICGGHIIEH7?BDECCC?AA@7?<=8;<?>@A4@CCC@B?BBB9A@@@@DCCCCC
@3CS
CCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCC
+
CCCFFFFFGHHHHJIFGGIJIIJIJJJJIGIJGIIIIEEHIGIBHIIAGHGHIJJHIJJIIGGIGJJJGHHHHFFFFFFDEECEDBACDDDDDDDDDDDDD
@3CT
CGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTAT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHFFFFFFDDDDDDDDDDDDDDDDDDDDDDDDDDCCDDEDDDDEDDE
@3CU
CCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCAT
+
@@@DDDADDHF><EFGGECGGIG9ACBA9<C3:?D9F@DF>9GEC@;80?DB3B=(=CF;;AHEABB>>7=.6>66;5;;/;@=<<?ABB<@<@2(4:@C:
@3CV
CTCCAACTTTGCTTACCTCTTGGCCTCTAAACTTAGCCTCTCACCAAGGGAGCATCCCCTCAGTCCTCACCATGCCTCAGGAGGTCAGGGCAGCCAGAG
+
@??DAADDFBF?FGHBDGHHEEHEDFGIIIIIGIIIIGGIIIGIGGIIIIIGIIGHFGIGEIIIIIEHCEEHHEEEEECCCCCBBCC?ABBBBBBBBBB
@3CW
CAGCTTTCAGTCAGATGTATATGCATTTGGAATTGTTCTGTATGAATTGATGACTGGACAGTTACCTTATTCAAACATCAACAACAGGGACCAGATAATTT
+
@CCFFFFFHHDHHHCEHFHHHDFHCHGHIGHGCHIFBCFFGCGGIGGICBGHC<?DDBGGEGGGDDGG48C@@AF@GGGEHCHGFFHE?=BBDEBCDDDEE
@3CX
CCAACCCCGACGAGATTGAAATCGACTTTGAGACCCTGAAGCCGTCCACACTGCGTGAGCTGGAGCGCTATGTCACCTCCTGTTTGCGGAAGAAAAGGAA
+
CCCFFFFFGGHHHJJJJIJJJJJIJJJJJJJJJJJJJJIJIJJJIIHHGEFFFFD>CBDDDDDDDDDDDDDDCDDDDDDDCDDDDDDDDDDDDDDDDDDD
@3CY
GTCATAGAGAGCTTCCAAGTTGAGAAGTGTGTAACTGAGTATCAGGAAGGCTGCCAGGGACTGGGCTCCAGGGGCAACATTTCCCTGGGTCCTGGAGAAAC
+
?@?B?D?;AF=FFHIG@HBII>?@;FB<A9AFFBFB4C@?C@FE@@HB>DF>;BF?9;;7<F@@@=E6D;;;A</9=;?C>;;@CCC?79?BC>:2291>9
@3CZ
CGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTT
+
=??DDFFDFDDFHFIBBGHIIICE=FHAHIIEGGGIDHHGGGGGGCGEGG@FBEGGIIEHEFBDC@CB>@AEE?BCBACCCCCBB39@CC<CCCCCCCCAC
@3D0
GTAAATACAGTTATCCCCAGGTAACTGAGAGCTACACCATGCAGCCAGTAACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACT
+
-;98(2=96:.691):>>1(=8@)..;)949>?<))2)=?<??9)7=>=):8)).<199;99)3;>1=7:3((.).093=7(.:9=19;7-:(633278;&
@3D1
GGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATC
+
CCCFFFFFHHHHHJIJJJJJJJJJJJIJJJJJJJJJJJGGIIJJJJJJIJJJJJJJJJHIHHGHHFFFDEEEEDDDDDDDDDDDDDDDDDDDDDDDDDDDD
@3D2
CCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCT
+
@<@BD=DB?CFHDBBBGHIECDFGH>@AE0?CDGBBGF@F9BFAFEDFECCGIGIGGIGIGHCHHCAEHHE>BEECCC=BBBB>AB?CCCCDC@AAC?CCC
@3D3
CCTGTATAACCAATGGAAGTGGTGCAAACAGAAAACCAAGTCATACCAGTGCTGTCTCAATTGCAGGAAAAGAAACTCTTTCATCTGCTGCTAAAAGTGGT
+
CCCFFFFFHHHHGJJJJJJGHIHIJJJJIJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJHHHHHFFFFFFFEEEEEEEDDDDDD>CC:
@3D4
GCCTGTACAATGTCAGTGCCTATGATCAGAAGCCACAAGTGGGAATGAGGCCCTCCAACCCCCCCACACCATCCAGCACGCCAGTGTCCCCACTGCATCAT
+
CCCFFFFFGHHHGJJJHHJJJJJJJJJJJJJJJJJJIJJFHIJHIJJGIJIIJJJJIJJJJIJHDDDDDDDDDDDDDDD>BDDDCDEEDDDDDDDDDDDDC
@3D5
GTCTGAGCCAAACATCCCCTTCCCACCACAAGGCTTTAAGCAGGAGTACCACGACCCAGTGTATGAACACAACACCATGGTTGGCAGTGCGGCCAGCCAA
+
CCCFFFFFHHHHHJJJJIJJJJJJJJJJJJJJJJIJJJJJJJJJJJGFIIJJIJJJJHHHECHEFFFFFEDDDBDDDDDDACDDDDDACDDDDDDDDDDD
@3D6
CTCTTCACAACCTCTCCAAATACACAGACAAACTCCAGAAAGCAAGAATGCTACTCCCACCAAAAGCATAAAACGACCATCACCAGCTGAAAAGTCACAT
+
@@@FFFDFHHGHGGIJGGIGGIGIIJJJIIIGHIJJJJIJJIGGIIGIIJIIIIIGJJIIIHJJJGIHHHHHEEFFDD@CDDDDDD<CDDDDDDDDEDDD
@3D7
GTAAACTTAAAGCACTTAATGAAGAGCTTCATTTGCAAAGAATAAATCCAACTACAGTGAAAATGAAAAGTTCTGTCTTTGATGAAGACAAAACTTTTGT
+
@BBFFFFFHHHHGJJJJJJJJJJJIJJJJIJJJJJJJJIJJJJJJJJJJJJIJJJIJHHIJJJJJJJJJJHIJJJJJJJJJHHHHHGFFFFFDEEEEEDD
@3D8
TGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTT
+
CCCFFFFFHHHHHJJJJJJJJIJIJJJJJJJJIJJJJJJJJJJJJJJIJJIJIJJIJJIJDHHHHHHHFFFFFDDEEEDDDDDDDDDDDDDCDDDBDDD@C
@3D9
TGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCT
+
@@<:BDD=DDFF?B;?DF<CFFHIF@DFBFF;FGFBCC?FFFA=F=FF@CA@EIIEEAC=BDDBDCC33>5=@BAB><,5>@:AB::AD@(>@??83:AA
@3DA
CTCTGCCACAAACTGTGGTGATGACATCTCCTGTGACTCTCACCTCTCAGACAACTAAGACAGATGACCCCCAATTGAAAAGAGAAATAAGGTTAATGAA
+
@@@DDFFFFHHHHGDEDEEB<@FGHCBHHEFIDFFGGIHGHEHIIIIIIIBHGFECGGC>CGCGIGDEGIIFFBDF?@?AC;;;?C?;ACAA@ACCCCCC
@3DB
ATAATCACTGCCCAGCGTCCTCCGAGTCCCACCCGAAGCCATCCAGCCCCCGGCAGGAGAGCACACGCGTGATCCAGCTGATGCCCAGCCCCATCATGCAC
+
@@@DDDDDDBAF3EEEBG?<CD?D<GB?B?CF>G:?@0;=FBC@F3=;;;ABDCB:@B@???A?@88B;&)8>>@B@?BBA>@AAB:8<@BBBBBB>>>AA
@3DC
CTGGCAGCCGGAGTAGGCCTGGCTAATGCCTGCTATGCAATACATACTCTTCCAACCCAAGAGGAGATTGTAAATCTTCCTGCCTTCCCTCGGGAAAAACT
+
=@?1;?BADH?D?<A9BEB<:)??9:D<:94:?:BGHGGHGF><8?D===FH>78=AH?C@2>C2;;@D>(;;>>CCAAC:5;=C>C:(>5829508985@
@3DD
CAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGAAACTACAGTTATCCCCACGGACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCC
+
::++?)00<22ABB:=)):==)?;:?00090*0<A>>;A3)=B>)/)=3)7).7>=;='''3,'(,,(5;'99;922(+(+(+32+((53+8338;??97
@3DE
GAGTTTTCTTTAAGGCCAATTGACAGCAACACGTTTGAAATGAATGGCAAAGCTCTCCTGCTGCTGACCAAAGAGGACTTTCGCTATCGATCTCCTCATTC
+
@BCDDFFDDHGHFHGIJIIIGGJIJJIGIIIJIHIJJIJJJJGHIJJIIIIIIIGGIJIIJJIJIIIJJJHGHHHFFFFEEEDDDDDDDDABDDDDDDDED
@3DF
GGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTC
+
@@?BDDDDHHHHHJGIGIIIIGIIJ@HGIJJJGIJGGIJIJJJJIGIIHJHJJJGGJIGGIIIJJFCH>EHDEDDDDDEEEDDEDECDDCDDDDDCCDCD
@3DG
GAGGAAGTTTGAATCGATTGTGTCGCTCTGCTTGTGGTTGTCCACGTGAAAGAAAGGGCTCGGGTCGTTTAGCGGGGAGGGGAGGAGTGGGAGGGGCTTCT
+
79((((.)2)2))228((3(.)33(.((1)8@8).)()((0))..7:(6()<73)).((((',5(',98((((',&&&)&)0)&)5((2(((+&0&&&(((
@3DH
CCAAGAACTGCCCTGGGCCTGTATGCCGGATATTGACTCAGTGCTGGCAAGATCAGCCTGAAGGCAGGCGCAACTTTGCGATCATTTTGGCGAGGATGGA
+
000-2()2).;<()98;5>;5);;)))((((5)).<>?)).)0)).9576(.6)..))60))83(==5''''3'(((,,',+206656;5()558&++8/
@3DI
TGGAATTCTTCAGGGAGGGCTCCCGTGACTGGATGATGTGCACCACGCGGCCCAGCTTCTCGCCGGGGAGCTTGTTGATGTCCAAGCTGAGCTGCCGCTTC
+
CCCFFFFFHHHHGGIGGEHIJJGFGFGIIJJJJIIJGIBGIIHGGGHJJIGFDDDEDDDDDDDDDDDD7B9ACCDDDDD@BCDCDDBDCDDDDDCDBDBDD
@3DJ
TGTAAAATGAACAAGGAGGACTTCCTCCGCGCCACCACCCTCTACAACACGGAAGTGCTGTTGTCACACCTCAGTTACCTCAGGGAAAGTTCACTGCTGGC
+
@@@DFFFFFHHGHJJGGJGHIIIJJFIJGGHIJIJJJJJJIJFIIJJJJIJIHFEEECBEFFC@CEEEDDDDDDDECCDDDDDDDDDDB@CDDDDDC@CCB
@3DK
AGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGC
+
CCCFFFFFGHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJDHIJJJJJJJJ
@3DL
GTGCCCAGCAATCAGGTGGTCGTACAAACTGCATCAGGAGATATGCAAACATATCAGATCCGAACTACACCTTCAGCTACTTCTCTGCCACAAACTGTGGT
+
?=?DDDFFHHHDHHGIGGHFHGDGECGGJC??FGGIGIJGGIGIJIIJJGIGJJCHEDGHIICHFHGGGFFFFFDDAE@ACDDDDCDDDDABDD9>>:@C?
@3DM
TCGGGGTCTGGGCCATGGCGCCTTTGGGGAGGGGTATGAAGGCCAGGTGTCCGGAATGCCCAACGACCCAAGCCCCCTGCAAGTGGCTGGGAAGACGCTGC
+
+1=<A<<??@=;3AAA=A>A)1:)*:?=4)<A'5-:7777>7=A2==).;)6;<96=???===(8=05;11+28(5;;;29(38=?=9<&8(32;395;5.
@3DN
CCCACCTCAGTCTTCCAAGTAGCTGAGACCACAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACC
+
@?@?DDD?DAF<<CDDFBF?ABFE+<CABFB;GC?)10@@F07B3CFFAF@CF?=2@;??).7@@BDB:A6;@ABBA;;A3,>>A@9?<<B09<B>::<
@3DO
CAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTAC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJIJJIIJJJJJJJJJJJIJJJJJJIIJJJHHHHHFFFFDEEEEDDDDDDDEDDDDDDDDDDDDDDDDDDDDD9BDD
@3DP
CTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTC
+
CCCFFFFFHHHHHJGGJGHGIIIIJJHHGIIJJJFGIIIGIGGIIIIIHIJJJJBHHGHIIJICEIEIIHGHHFEDFFFEDEDEEDADDDCCDCDDCCCCD
@3DQ
AGAAGCCACAAGTGGGAATGAGGCCCTCCAACCCCCCCACACCATCCAGCACGCCAGTGTCCCCACTGCATCATGCATCTCCAAACTCAACTCATACACCG
+
CCCFFFFFHHHGFHIJJJJJJIJJIJJIIIJIJJJJJJJJIIJHHHHHFFDFACDBDCD@CCDDDDDDDDDDDDDDDEDCDDDDDDDDCDDDDDDDDDDDD
@3DR
CCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJHHHHHFFFFFEDDEDDDDDDDDDDDDDDDDD
@3DS
GGATCACTTCAGCTCTGGCAGTTTTTGGTAGCTCTTCTGGATGACCCTTCAAATTCTCATTTTATTGCCTGGACTGGTCGAGGCATGGAATTTAAACTGAT
+
<?@DDEDDFFHHDIFEDEGIG:FDHG:G:CFHHHBDB@F<:??FHGFHHIIHEF??BG>==BBCDACGG@EH@DEE97A45=>8=>AB>@>ACADA:@C4:
@3DT
CACAACACCATGGTTGGCAGTGCGGCCAGCCAAAGCTTTCCCCCTCCTCTGATGATTAAACAGGAACCCAGAGATTTTGCATATGACTCAGAAGTGCCT
+
CCCFFFFFHHHHGEHIIGIIIIIGGGIIJJJJIJIJGGGIIJIJIIJEEEDHHHFHHFFFFFFDDEEDDBBDDDCCDCCDDEDDEDDDDDDDDDDDCDD
@3DU
CCCCAGGCCATCCGTGGATAATGTGCACCATAACCCTCCCACCATTGAACTGTTGCACCGCTCCAGGTCACCTATCACGACAAATCACCGGCCTTCTCCTG
+
CCCFDFFFHHHHGGFFHIIIJIIIHJJJJJIJJIJJJJJJJJJJJJJIIJJJIJIJJJJIJFHFFFFFEEEEEDDDDDBBDDBDCCCDDDDDDDDDDDDDD
@3DV
CTCATCCCAGCAGAACAGAAGGCTGTATGTTTGAAAAGGGCCCCAGGCAGTTTTATGATGACACCTGTGTTGTCCCAGAAAAATTCGATGGAGACATCAA
+
8=+4AAD=<D;BDEEEEIE>BD@<F+A<B9CBECEFADDDCCD<DDIDDDCEA4@CEEIIE;CCC>C?3.7?D@DAAA?AA??;55=A3>?A9:(544:4
@3DW
CTTTGTGGATGGCCTGATGATCCACAGCGGAGACCCTGTTAACTACTACGTTGACACTGCTGGGCGCCACGTGTTGCTCAGACAGGGTGTGCTGGGCATC
+
11:1D=BDFFHFFIGIIGCHAE@EGDGGIGGIFDHIIDBDHHFB=CBCFCC@FCGGIIECAE)5;?/;@>=5<5?@<@ACCA(838?3<)8>:AC<8???
@3DX
GGAAAGCAAAAGGAGCAGAAATAAAGACAACAAATGAAGTTGTTTTGGCTGTGGAGTTTCACCCAACAGATGCAAATACCATAATTACATGCGGTAAATCT
+
CCCFFFFFHHHHHGIJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJHIJHIDHIJIJJJJJHHHHFFFFFEDEEEEDDDDFECDEDDDD=@DDEDD
@3DY
GACAACTAAGACAGATGACCCCCAATTGAAAAGAGAAATAAGGTTAATGAAAAACAGAGAAGCTGCTCGAGAGGGTCGCAGAAAGAAGAAAGAATATGTG
+
@@@DDDFFHHGGFDGHGIGIGIIIIFGIIIFEIIIIIEIIIIIGIIIIIABHEGGHGIEIHIEHGGAHEHD?B(9;;>28;;CDDDBC?ACCC?CDEE@D
@3DZ
CTCAGGAGGCAGTTCCGTTCTGATGTCATCATAGTTGTCAACATCGGAAGGAATGAACATGGTAATTGGCCGACCGCGCATAAACATTTTAATATATTCTC
+
@@;BDDADFFBBABFHIHIIIE>HG4BBFHGBG4?DGHCDGHGCHHIIIIGGHBDBCF@CDFFGEHG=CHE4?DC@B??@BBCCACCCEDDCCDDDDEE:@
@3E0
CTCATTCTAATGATCAAAGTCCACAAATTCGAGCATCACCTTCTCCCCAGCCCTCTTCACAACCTCTCCAAATACACAGACAAACTCCAGAAAGCAAGAAT
+
@@CFFFFFHHHHHJJJJJJHIJJIJJJJJJJJJIJJJJJJJJJJJJJIJFIJJJJJJIJJJJJJJIIJIHHHGGFFCFDFEEEDDDDDDDDDDDDDDDDDD
@3E1
CAAGAAGGAGAATATATTAAAATGTTTATGCGCGGTCGGCCAATTACCATGTTCATTCCTTCCGATGTTGACAACTATGATGACATCAGAA
+
C@CFFFEFHHGHHJJJJJIJJJJJJIIGIJJJJIJGIIJJIJJJJJIJJIJIJJGHHHHHHFFFFDDEECDDDDDDDCDC>CDDDDDDDDD
@3E2
CCCAGGCAGTTTTATGATGACACCTGTGTTGTCCCAGAAAAATTCGATGACATCAAACAAGAGCCAGGAATGTATCGGGAAGGACCCACATACCAACGGCG
+
CCCFFFFFHHHHHJJJJJJJIJJJJJIJJJJJJJJJJIJJJIJJJJJJJJIJJJIJJJJJJJJJJJJIJHHHFHHGFFDDDDDDDDDDDDCDDDDDDDDDD
@3E3
GGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGC
+
?@:BDDDDFFHBFEGGGG<FHDGIEEGBHGHIGGEGDDBBGIGIGEFGGGIGEGEHGAHGDHFAAE;;BB?@CCCCC@ADCAAAD@::>CBBBCCCCCB
@3E4
GAGAAATTAGAGCTGTCACAGAGACTGTCTGATCTTTCTGAACAATTGAAACAGAAACATGGTGAGATTAGTTTTCTAAATGAAGAAGTTAAATCTTTAA
+
B@@DDDDFHHDHHIJIIGIIGIGHJJJIHJIIGGGIIIJIIIGHGHJGGIJHIGCFI@?FHJ=CCHGGIHIFHHIJJHIHHHHGFFFEEFFFEEEDEEED
@3E5
AAGACTCTGTGTGGGAAAAAGAAATAGAAATACTTATAGAGGAAAATGAGGACCTCAAACAACAATGTATTCAGCTAAATGAAGAGATTGAAAAGCAAAGG
+
CC@DFFFFHHFFFHIIIIJJJIIIJJJIJJJJJJJJJJJGIIJJJJGIJJIJJIJHGIJIJJIJJJIIGHHHGHHHFFFFFFDEEECEDDDDDDDDDDDDD
@3E6
CCCAGCAGAACAGAAGGCTGTATGTTTGAAAAGGGCCCCAGGCAGTTTTATGATGACACCTGTGTTGTCCCAGAAAAATTCGATGGAGACATCAAACA
+
CCCFFFFFHHHHHJJJ3CHIHJJIJJJJJJJJJJJJJJJJJJJJJHIJJJJJJIJJJIJJIJGHJHHHHHFFFFFEEEEEDDEFEDDDDDDDDDDDDD
@3E7
CCGGGAGAGATGCTGGAAGAAACTTCTTAAATGACCGCGTCTGGCTGGCCGTGGAGCCTTTCTGGGTTGGGGAGAGGAAAGGAAAGTGGAAAAAACCTG
+
CCCFFDFDHHGHHJJJIIJJJIIJJJJJJJJIIJJJJJJIIIJJIIJJIHJHHFFFFDECCEDDDD;?BDDD?B<BDBDDDDDDDD>CCCCDDDDDDDD
@3E8
CAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCC
+
CCCFFFFFGHHHHIIJIJJJJJJJJJJJIIJJJJJIJJJJJJJJJJJJJJJJJJJJJJIHHGHHHFFFFEEDDDDDDDCCDDEDEDDCDDDDDCDDDDDDD
@3E9
TCAGAAGCCACAAGTGGGAATGAGGCCCTCCAACCCCCCCACACCATCCAGCACGCCAGTGTCCCCACTGCATCATGCATCTCCAAACTCAACTCATACAC
+
CCCFFFFFHHHHHJGHIJHJIIJHHJJJJJJGIJJJJJJJJIJJHHHHFFFFFC9ABDDADDDDDDDDDDDDDDDDDDDEDDDDDDDDCDDDDDDDDDDDD
@3EA
GAAAAATTCGATGGAGACATCAAACAAGAGCCAGGAATGTATCGGGAAGGACCCACATACCAACGGCGAGGATCACTTCAGCTCTGGCAGTTTTTGGTAGC
+
CCCFFFFFHHGFFHIJJJJJJJJJIJJIJJJJJJJJJJJGHGIJIJFIJJGIJJFGIIJHHHHFFFCDB=BDCCDDDDDA@CCACCDDC?9@CCDDDDDCD
@3EB
CTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHBEFFEDCEEDDCCDDDDDDDEEDDDDDDDDDDDDDDDEDDDD
@3EC
CTCTCCAACTTTGCTTACCTCTTGGCCTCTAAACTTAGCCTCTCACCAAGGGAGCATCCCCTCAGTCCTCACCATGCCTCAGGAGGTCAGGGCAGCCAG
+
::??DDDDDHDHDIIGFCFIGAHEGBEBGEHIGEHIICFGBHGGGAHIDFIFIBG==FCFH;AH;=EEFHFEEDB>@@CE>>C:;;?=C<?BBB@@B<A
@3ED
CAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCATCCAGTCACTGCACCTCCATCCTACCCTC
+
CCCFFFDFHFHGHIIEIIIIIIJJJJJIGI?FGGIGHIIIIIJJJJIIGH9BDHHIJIIJIIJIIJHDHHFFFDFFEEEEEDACCDDDBDDDDDDDDDDDD
@3EE
TTTGTCACCAGTGGAGGCCGGATGGACCCACCCAAGAACTGCCCTGGGCCTGTATACCGGATAATGACTCAGTGCTGGCAACATCAGCCTGAAGACAGGCC
+
C@CFFFFFFHHHHIGIJJIJJEGGIGIIIIJGIJJIIJJIIIIIGHGIJIJICHHFHHDFDCDDDCDDCDDDDDDDDDDDDDDDDDDDDDDDDDDDCDDB@
@3EF
GTGAAATGCCTGGAAAACCGAGTTGCAGTCCTGGAAAATCAAAATAAAACTCTAATAGAAGAGTTAAAAACTTTGAAGGATCTTTATTCCAATAAAAGTGT
+
CBBFFFFFHHHHHJJJJJJJIJHIJJJJJJIJJJJJJJJJJJJIJJJJJJJJJJJIJJJJJIJJJJJJJJHHHHHFFFFFFEEEEEEDEEFDDDDDDDCCC
@3EG
ATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCA
+
CCCFFFFFHHHHHJJJJJJJJJIJJJJJJJJIJJJJIIJJJJJIJJJIJIJJJJJJHHFFFFDDEEDDDDDDDDDDEDDDDDDDDDDDDDDDDDDEDDDD
@3EH
CAGCAAGGTACAACTATTCTTCAGTATGCACAGACCTCTGATGGACAGCAGATACTTGTGCCCAGCAATCAGGTGGTCGTACAAACTGCATCAGGAGATAT
+
C@@FFFFDDHHGFHIIIIJIGEGIFIIIJDGHEHGIDGGIIGHJJIJIJIJJJJJGIJIIIJIJIJGIJJJJJ>EFEHEBBACDEDDDCCCDDCCDDDDDE
@3EI
GGATGAGACAATGAGAGAATTTTTAGAGTTGACAGAACAGAGTCAAAAATTACAGATTCAATTTCAGCAATTACAGGCTAGTGAAACTCTGAGAAACAGC
+
@@@FDBDFGFDFHEGFHEIGIHGHIGGHBEHDFCGGGGIDGG?FEEGIHIGIFHCHBFCCFHGGAGHAGAGGIGGGC?EEH>B?@DFC@CCEECCCACDB
@3EJ
TCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAA
+
CCCFFFFFHGHHHJJJJIIJJJJJJJIIJJIJJJJJJJJJJJJIGIJJJIJJJJJJIIJJJJHFFFFDEEEEDDDDDDDDDDDDDCDDDDDDCDDDDDD
@3EK
CAAATTCTCATTTTATTGCCTGGACTGGTCGAGGCATGGAATTTAAACTGATTGAGCCTGAAGAGGTTAGTTTAATAGATTTTAATTAGGACACTCAGAC
+
CCCFFFFFHHHHHJJJJJJJJJJIJJJJHHIIJIIJJJJJJJJJJJJJJJJJJJIJJJIJIIJGHI?EHHHHFFFFFFEEEEEEEEEEDDDDDDDDDDDD
@3EL
CAGAGATTTTGCATTGACTCAGAAGTGCCTAGCTGCCACTCCATTTATATGAGGCAAGAAGGCTTCCTGGCTCATCCCAGCAGAACAGAAGGCTGTATGTT
+
@@CDBDDFHFFFDGIJIIIGIJIIGHHIJGIJJIJJJIJJGEGHIJJJJIJJJJJIIJJJJJJJIGIJIJIJJJFHHHEDFFFFDDC;AC>BBDBDDEEDD
@3EM
GGAATTGTTCTGTATGAATTGATGACTGGACAGTTACCTTATTCAAACATCAACAACAGGGACCAGATAATTTTTATGGTGGGACGAGGATACCTGTCTCC
+
CCCFFFFEHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHH?EFFCEDDDDB?CCDDDDDDDD
@3EN
AGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTAACCTCCTACCAGCTATTCCTCTACACAGCCGACTGGTTATGATCAGAGCAGTTACTCTC
+
+1+<7+2@<27+?C372++@33?22+?A=1@:3?A>7=A??*)0000>==B*.(..8>4>B77.7>>>(=;A4'9'.(-(5((-;95;595(,,,,(533
@3EO
CCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGT
+
@@@DDDADDHGDFIIIHIGGDHGIIGGGGDDEHGGIIGIIIEIGHIHIIEHHICHGGIIGIHGGHHDFFABA>A>CCCCDDDCDDDDD<?BABBDDBDC
@3EP
GAAAGCCTTACAGAAATCTCCAGGACCTCAGCGAGAAAGGAAGTCATCTTCATCCTCAGAAGACAGGAATCGAATGAAAACACTTGGTAGACGGGACTCG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHHHFFFFFEEEEDDDDDDDDDDDDDDDDDDDD
@3EQ
GGGAGGTGAGCAGTTTGTACCAGACTATCAGGCTGAAAGTTTGGCTTTTCATGGCCTGCCACTGAAAATCAAGAAAGAACCCCACAGTCCATGTTCAGAA
+
<?@DDD+<<DFDFFF<EGHEHFEIG><BFFF3;FAFFIIBF4BFDGEEEIFFIFIFE7B@@@@CCEE77=CA>EEBDDDB@CC;>B?ABBBB@AA>@@AB
@3ER
CAAGAGTACATCCAAGCCATTATGATGATGGAGGAATCTGTTCAACATGTTGTCATGACAGCCATTCAAGAGCTGATGAGTAAAGAATCTCCTGTCTCTGC
+
C@CFFF:BFHFHGGIJJJJJJJJJHHIGIIIHJIJIJEHIGGIJJIJIIGHJIIJIIHIJJIGGGIFHHGGE@7CEGEAECHHFFFEFDACEEEEDDDDDC
@3ES
GGTGGGACGAGGATACCTGTCTCCAGATCTCAGTAAGGTACGGAGTAACTGTCCAAAAGCCATGAAGAGATTAATGGCAGAGTGCCTCAAAAAGAAAAG
+
@@@FDDDDFAFHHJJJIIJHIIEHHIJGIIGIGHEGIJBDCHGIIH@HIJJHIJJIJJIGHHHHFDFFFECEEDEEDDDD@DCCCCDCDCCCDDDBCDD
@3ET
GGTAGCCGAGCCGGGCGACCTAGAGAACGAGCGGGTCAGGCTCAGCGTCGGCCACTCTGTCGGTCCGCTGAATGAAGTGCCCGCCCCTCTAAGCCCGGAGC
+
@@?DDDFDFFHFHIJJJGJIJJIJJJJIIJJJJHFBDBDDDDDDDCD@BDBDDDBCDCA>ABD;@BDDDDDDCDDCD@C@ACBBBDDDDDDDCCDDBBB>9
@3EU
CTGGCTTACATGAACCACATCATGGTCTCTGTCTCCCCGCCTGAAGAGCACGCCATGCCCATTGGGAGAATAGCAGACTGTAGACTGCTTTGGGATTACGT
+
@@@FFFFFHHHGHIGGIJIGGGGIJHHHIJJHIHIJIGGJJDIIJIGHJBHGGHGHIJGECEFEAB?BDCAECEDCDDCCCDDECCDDDDDDC>8:>ACB?
@3EV
GACTATGACAAGCAGGGGTGCTGAAGGATCAGTTTCTAAAGTAAATAAAAGTTTTGGTGAAGAATCAAAAATAATGGTGGAAGATAAAGTTTCTTTTGAA
+
CCCFFFFFHHHHHJJJJJCFHJJJJJJJJJJJIJJJJJJJIDHIJJIJJJJHIIJJJGHIIGIJJJHHHHHFFFFFFAEDDDDDDDDDDBCDDDDDDDBC
@3EW
CAGAAGTCATCAGAATGCAAGATAAAAATCCATACAGCTTTCAGTCAGATGTATATGCATTTGGAATTGTTCTGTATGAATTGATGACTGGACAGTTACCT
+
@@@DDD=AFHDDDEBGIGA>CBGGGGEGGBFHECAEEF@GI<CGCB?G>BGB<><BE?@BAEGEGCGEEBE@AA@@>DAAAAGAAEA=AHFD>BD;>A>@@
@3EX
TATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCC
+
CCCFFFFFHGHGHJIGIJJIJJJJJJJJJHIJJJJJJJJIJJJJIIJJJJJJIJJIJJJJJJGEHFHGFFEFFFACCEEEDDCDDDDDDCDDDDDDDDBDD
@3EY
CTGAAGCAGAGGAAACCTCGGATTCTTTTTTCACCATTCTTCCACCCTGGAAACTCTATACACACACAGCCGGAGGTCATACTGCATCAGAACCATGA
+
CCCFFFFFHHHHHIJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJIJJHHHFFFFDDDDDD?CDDEDDEDDDDDDDDDDDDDD
@3EZ
CAGGTATTAATGGAAAGACTCAATCAATCTGATTCTATAGAAGACCCTAACAGTCCAGCAGGAAGAAGGCATTTGCAGCTCCAGACTCAATTAGAAC
+
BBCFDDFFHHHHHIJJJJIJJJGIJJJJJJJIIIJJJJJJJJIIIIJJIJIIIIJJJJGIJIGHIIJIIJJIIJHHHHHEFFEFDDECC>@DDDDDC
@3F0
GTACAGAAATCCGTTCAGGCCGGTCAGGCATCCCCTGCCTGGAAGGGACCATAGTGAGAGATGCCTTATATTCCTATATTCCAGGCCAGGAC
+
7((-(.)24))2(2)<@)..;8-1=()))(0))(7<=(()).<)653=(3:)).8:)<;>()83.9=(6(6=>;6;(7;;=1(5;8;6;(8(
@3F1
GGAGTGGGTCCCATCAGTTTGAACAGTTGTCTGGATCCATTTTGTGGATGGCACCAGAAGTCATCAGAATGCAAGATAAAAATCCATACAGCTTTCAGTC
+
@@CFDDFFFHHHHIJJJJJJJJJJJJIIIIJJJJJJJJJJJJJJFHIHGIIJIJJJJJJJGGIJJJJJJJIIHHHFHHFFFFFEEEEEDDDDDDDDCDFD
@3F2
CTCATACACCGAAACCTGACCGGGCCTTCCCAGCTCACCTCCCTCCATCGCAGTCCATACCAGATAGCAGCTACCCCATGGACCACAGATTTCGCCGCC
+
CCCFFBDFHHHHGJJJJJIJJJJIJIGIGIGIIIJIIJJGIIJIJGIJFFHEE?DFCDEEEEDDDDDDDCBDDDDDDDDCCDDCBDDBDDDDDDDDDDD
@3F3
CTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTTATGGGC
+
CCCFFFFFHHGFDIJJIIHIJJIJJJJJJJJJJJIGIJIJJJJJJIIIJIIJJJIIGHIJIIHGHHHFDDDEDDDDDDDDDACCDCDCDD9<9BCCDDDDD
@3F4
CAGGCACCAACTAGCCTAGAGCGTATACAGGGTGCTTTGGAAGAAGTCCAGAGAGAGTGACGGATACGGGGGAGATAGTGGAGAAAGGGAGTGAAAATGTC
+
07(<3((((.:1))))2.9>11((2()9)))(2:=1)).))))())0)0)).(.(6(.).)('''')(,'3'00&(52((+(+(+(++68&((((32((+:
@3F5
TATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCC
+
CCCFFFFFHHHHHJJJJJJJIJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJIJJJJJHHHFFDDDDDDDECDDDDDDDDDDDDDDDDDDD
@3F6
CTTCTGGATGACCCTTCAAATTCTCATTTTATTGCCTGGACTGGTCGAGGCATGGAATTTAAACTGATTGAGCCTGAAGAGGTGGCCCGACGTTGGGGCAT
+
CC@FFFFDDHHHHIGGHGFHIIEHIJJJIJIJID@GGHJIJIIG?DEHGIJEGIJJJJJIJJIJIJGHEHHHHFFEFFDCAC6=@BBDDDDD9B@?<BDDD
@3F7
CCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATG
+
CCCFFFFFHGHHHJJJJJIIJJIIJJJJJJJIIIJJJJJJIJJIJJJJHIIIJJJJJJJJJJJHHHFFFFFEEEEFEDDDDDDDDDDDDDDDDDDDDCCDD
@3F8
GTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACT
+
@@<DDDDDHHF>?EBCCEF?C=C4ACHG@@F@C?GH>GHDD?DB?GHHB@FHGDC3BFHAEHIICDECEEHEE@D:;;>ACA@@>DCAC>A:9:?59=B<<
@3F9
CAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGC
+
@@@FDDDFHGHAFHIJJJJJJJJJJJJJJIIIIEHHGIIIIIJIIJJIJIIIJJJIJJJGJIIJIGHHEHFHFFFFFECCDDDDBDDEEEDDDDDDDDD
@3FA
GTTTGAGGCTGAGGAGATGCAGATTCAGAACACACAGCTGATGAATGGGTCTCAGGGCCTGTCTCCTGCAACCCCTTTGAAACTTGATCCTCTAGGGCCCC
+
CC@FFFFFHGHGHJJJJJJJJIIJIJJJJJIJJJJJJJJJJIIJJIJJJEHIJIJJJIJIIIJJJJHHHHHFFFFDEEEEDDDDCCDDDDDDDDDDDDDDD
@3FB
CTTCAGCTCATCTTAGGCTGTGCTGTGAAGTGTGAACAGAAGCAAGAGTACATCCAAGGCATTATGATGATGGAGGAATCTGTTCAACATGTTTTCATGAC
+
@?@DD?ADDF?ABE@2+2A3CFA?BEHH>2<A<E94?*:C@;19??3)099?F**/*9(/8)84B@).8)/)))(-(=7.777;7?7.;@(.6(,-(5(5(
@3FC
AGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACC
+
CCCFFFFDHHHHHJJJFIJIJJJJJIJIJJJGIHJJIJIJIJJIJJJJHGJJJJIIJJJJJGIJJHHHHFFEFEEEEECCDDDDDDDDDDAADDBDDCCDD
@3FD
CCATGGACCACAGATTTCGCCGCCAGCTTTCTGAACCCTGTAACTCCTTTCCTCCTTTGCCGACGATGCCAAGGGAAGGACGTCCTATGTACCAACGCC
+
CCCFFFFFHGHHHJJJIJIJJJJJJJJJJJJJJJJIJJJJHIJJJJIIJJJJIIJIJJJHHHFFDDDDDDDDDDDDDDCDBDBDDDCDDDDEDDDDDDD
@3FE
AATTCTTGGGAAAATTCAGATGATAGCCGTAATAAATTGTCGAAAATACCTTCAACACCCAAATTAATACCAAAAGTTACCAAAACTGCAGACAAGCATA
+
@@@FDDFDHDBDBHAFHDHFHHEIIGHHIIEHIIGHIIIFD@GGIGDDBFDDCCCGGBFHEHIIGIHCHHFHFFEC;;ACC@CBB?CDCCCCBDCDA<CC
@3FF
GTCCACTTGTGGAAGAGGAAGAGAAAGTGCCTGTGAGGCCCAAGGACCCTGAGGGGGTTCCTCCTCTCCTGGTCTCTCAACAGGCAAAAGGGGAGGAGG
+
=>=7A=2AC22@A<;A=+33<++2?;<CABBAA@A7=31??AA=)=//79>7A<<A<@=;;>>=;35;>????>=:;(,;5;;<089++(2005;5;09
@3FG
TGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTC
+
@C@DFEDDFFHHFEGGIIGHJGEHJJIGGGHGIIIIGJGIGHIGIGIJIIIJJIGGGIJGGGIEEFFDCEDDDDCDDDCDDDDDDDCC@CACCCCDD@BDD
@3FH
GAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACC
+
==???BD;FFD>HBHGIGFHGFHBHGIHCGGIFHEG;FHDFD8?D;@G@GE@=<5.;?.?6;ADCFC;@C:?@=/8???BB+9AACC<@44>AACCCA8<
@3FI
CAAGAGCCAGGAATGTATCGGGAAGGACCCACATACCAACGGCGAGGATCACTTCAGCTCTGGCAGTTTTTGGTAGCTCTTCTGGATGACCCTTCAAATTC
+
@CCFFFFFHHHHHJJHHIJJIIIJJJJJJJJJJIIJJJJJJJJJHHFDEEEEEDDDDDDDDDDDD@?CDDDBD?CCCACDDDDDDCDCDDCDDDCDDDCD@
@3FJ
CCTAACGTTGCAACTGGGAGACTTCCGGGGGCCTCACTGCTCCTAGAGCCCTCTTCGCTGACTGCCAATATGAAGGAGGTACCTCTGTTCAGGCTACGTC
+
@CCFFFFFHGGHHJJJJJIIGHJJJJJJIIJJIJJHHGHHFFFFFFEDCEDDDDDDDDDDDDCDDDDDDDDEEEDDDDD2>CDDDDDDDDEDDDDDDDDB
@3FK
CAGCAAACTTCCATATCCTGTTGCCAAGTCTGGGAAGCGAGCTCTAGCTGGAGGTCCAGCCCCTACTGAAAAGACACCCCACTCAGGAGCTCAACTTGGGG
+
@@@DD?DDHHDFHE<:?C<FACE<@HBB2<?C@F3??DF@??@FBDFD4BF2(<-=@FHHGHE=CHEC@DE@DCCAC?>;?????CAA@??@AA?:::@<@
@3FL
CAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAAC
+
CC@FFFFFGHHHHIJIJJJIJJGIIJIIJIJGIIJJJJJIGIJJIJJJJJJJJIJJIIJGIJJJHHGGHFFFFFFEEEEEEECDDDDDDDCCDDDDCDDDD
@3FM
AGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGG
+
CCCFFFFFGFHHHJIGIIJJJJJIIGHIIGIJIIJJJJJJIJJJIJJJJJJIIJIJIIJJJGIIHGHHHDF:@DFFCEEEEEACCDDDDDDDCDDCCDCCB
@3FN
AGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGAC
+
BC@FFFFFHHHHHJJJJJJJJJGHJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHHFFFFFEEEDEDDDEEDDDDDDDDDDDDDD
@3FO
GTCAAGTCAGACTCGGCCTAAAGGAAGTGTAGGCCATCCGGCTTGAAGCTTAGTGGCAGTGCTTACACCTTCAACCCTGGTCAATTGTTTGGACAAACTTC
+
--;?(=.@)))))3(=(((<)).)2).@)):@.=)=))(((-((7(<>1).)).)((.(:>)<)<))):))6.=(('(((-(((,(((((((,;(((+(((
@3FP
GGTAACCTGGGGCTGGAGGGAAGCTGTACTGTCCCACCTAACGTTGCAACTGGGAGACTTCCGGGGGCCTCACTGCTCCTAGAGCCCTCTTCGCTG
+
@@:DDBDDFF?AFEGIBFCHFHGHGACFHHGIIIIIGGGHIDFFHG>BHIIGHIIIBEEAE=BDCBC@@<?C?CCCCCC?A@A>ABBCBC>@<@5>
@3FQ
CTGGGCCGCGTGGTGCACATCATCCAGTCACGGGAGCCCTCCCTGAAGAATTCCAACCCCGACGAGATTGAAATCGACTTTGAGACCCTGAAGCCGTCCAC
+
@@@FFFBDFADDC?C@BBHGGIGDA9??<9DHIGHI<FHEHEEHHCEFFFFFD3@AEC:8;28;;BBBCCC>AAC?2>B?AC><8:?ACCCCCCBC<@@BA
@3FR
GGATAACATTCATGATACTGTGATTATTTGTCTTGTTTTGTTGTTTTTGTTTTGTTTTTTTAATCTTCTAGAAAGGAATGTTTTTGATTTTCGTTCTCCA
+
CCCFFFFFHHHHHJJJJJJJHIIJJJJJJJIIJJJJJJJJHIJHIJJJJIJJJJIJJJJJJJIHHHHGHHFFFFFEEEEEEEEDDD@DDEDEDDDDDDDD
@3FS
CACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATG
+
@CCFDFFFHHHGHHHIIJJJIIJJJJJJJJJJJJIJIJJGIIIJJJJJIIIJJJJJJIHHFFDDDDDDDDDDDDDDDDDDDDDDDDDDCDDDDBDDDDDDE
@3FT
CTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATG
+
CCCFFFFFHHHHHJJIJJJJJJJJJIJJJJJJJHIJJIJJJJJJJJJJJJHHHHFFFFFEEEEEDDEDDDDDDDDDDDDDDDDDDEDDDDDDDDDDDDDDD
@3FU
GACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTG
+
@@@FDDFFHFFHDHIIJIIIJIGIIGJJJGGGHGGIJIHIJIIFIIIGGHHGHGIGHGHGHHHGFFFFE?CEEEEDDDDDDDD5??B?ACCCC@BBABBCB
@3FV
TCTAAATGAAGAAGTTAAATCTTTAAAGCAAGAGAAAGAACAAGTTTCATTGAGATGTAGAGAGCTAGAAATCATTATTAACCACAACAGGGCAGAAAATG
+
=:?DA;BD?FDHHDIIIIECHIEHICHB>?FH@CDBAGCDFGFDFDE<F<??GIEBFHHCGEHGBGBAD@@CHHGEA@DD?AHEBB;5;>A=;?8;?CA@C
@3FW
CGTACCACAGGCGCAGTTATTCTCTTAATCGCCCACGGGTTTACATCCTCATAACTACGCTACCTAACAAACTCAAACTACGAGGGCAATCACAGTAGCAT
+
00(-(()2((.:>35-().4))=81:>?))((1<=1((((-())))))./81)83<9.(-,,,(66(39-3,(508;;(3((,&&)&2(++8(65+(++38
@3FX
ATCCAGAAGCCCTTTTCTCCATGGCCTTTCCAGATAATCAGCGTCCACTGCTGAAGACAGACATGGAACGTCACATCAACGAGGAGGACACAGTGCCTCTT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJIJJJJIJJIJJJJJJJJJJJJJJJHHHFFFFFEEEDDDDBDDBDDDDDDDDDDDDD
@3FY
CTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTT
+
CCCFFFFFHHHHHJJJJDHIIJIIJIJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJIJJJJJJJJIHHHHFFFFDEEEEEEDDDDDDDDDDDDDDDDDCD
@3FZ
CTTCAACACCCAAATTAATACCAAAAGTTACCAAAACTGCAGACAAGCATAAAGATGTCATCATCAACCAAGAAGGAGAATATATTAAAATGTTTATGCGC
+
CCCFFFFFHGHHHIJJIIIJIJIJJIJIIGIJJJJJIIGGIJJIJIJJJIIJJHICHCEHJJJJJJJJJIIHFGGFFFFEDEEDFEEEDDED@DDDDDDDD
@3G0
TGCAAAGAATCCCACGGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN
+
13;8>>44.)9>?1(((####################################################################################
@3G1
TCCAGAAGCCCTTTTCTCCATGGCCTTTCCAGATAATCAGCGTCCACTGCTGAAGACAGACATGGAACGTCACATCAACGAGGAGGACACAGTGCCTCTTT
+
C@CFFFFFHHHHHJJJJJJJJJJGIIIJJJJJJJJIIGIIIHHJJGIGIJIJIJJJJJJJJIJJJIIJHHHHFDFFFEEDCDDDD?BBCDCBDDDDDDDDD
@3G2
TTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGC
+
CCCFDFFFHHHDHJJBGHIHIHJJIIIIGIIGIJIJJJIGIJIJIIIJJJJIJJIJGGJJJJJCEH?CEEFFFFCACCE@ABD;CCC?CDDDDDDDDDD?B
@3G3
AACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCC
+
CCCFFFFFHHHGHJJJJJJJJJIJJJJIJEGHIJJIJJJJJIIJJJJJIDDHIIJJGGIIIJIJJIHHHHHFEEFEEEDCECDCDCDDDDDDDDDDDDDDD
@3G4
CCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGC
+
@@@DAD:BDHFHHG;@EEHIIIIGHGGGGGGIIDGGGEGIGIIEGIIIIGAFGHIEIIIGIG>GICHFEHHEEEE@BCCCCCB:?BBCCDDCCCDC:A4>C
@3G5
GTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGC
+
@@@FFDFFHFFHHIIGGIJJIHIDHGGGHIIJJJJGIIJGHJGIJIDD@EIGHEH;C@7;BDBECECECCACDD?AB?5:>CCCBDB?9<@CCD@DDDC
@3G6
GTACAACGAATGGAACAAGAAACACAAAGAAAGTTAGAACAACTCCGGGCAGAGCTGGATGAGATGTATGGGCAGCAGATAGTGCAAATGAAACAAGAATT
+
@@@FDFFFHHGHGJJJJJJGIJIJJGGJJGIIJADHIIJIJJIJGGIJIIFIGIJJJHHHHGFBEFFFCECEDC??DDDCCC:AADDDCDDDDDCDDDDDD
@3G7
ATTTTCTTCTGGACCTGGAGCGGCAATTCACTAACAAGAAAACAGGGAATTTTTGGGAAATATGAAAAGCCAAAATTTGTGCAGTGTTTAGCATTCTTGGG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJIJIJJJJJIJJHHHFFFFFFEEEEEEDDDDDDDDDCCDEDDDDDDDDDDEDDEEDDD
@3G8
GTCTAATGAAGAACAGGGAAGCAGCTCGAGAGTGTCGTAGAAAGAAGAAAGAATATGTGAAATGTTTAGAAAACAGAGTGGCAGTGCTTGAAAATCAAAAC
+
CBCFFFFFHHHHHJJJJJIJJJJJJJJJIIHIHHFIIFHIIJJJIJIJJJIIIIJJJIIJJJJJJHHHHHHFFFFFEE@CDDDD;@@CCCBDDD@@CCDD8
@3G9
GTTCAACATGTTGTCATGACAGCCATTCAAGAGCTGATGAGTAAAGAATCTCCTGTCTCTGCTGGAAATGATGCCTATGTTGACCTTGATCGTCAGCTGA
+
CCCFFFFFHGHHHJJJJJJJJJJIJJJJJJJJJJIJIJJIJFHIGJJJJJIJJJJIIJJJJJJJIJJJJJJJJJJJIIJHHHHHHHFFFFFDEDDDDDDD
@3GA
CAACAAGAAGATGAAATCACTGTGCTAAAGGCGGCTTTGGCTGATGTTTTGAGGCGTCTTGCAATCTCTGAAGATCATGTGGCCTCAGTGAAAAAATCAGT
+
B@CFFFFFHHHHGJIIJJJJJJIHJIJJJJJIIJIIJJJJIIIEHGAHIIIGGHGFDDDDDDDDDDCDDDDDDDDDDDDDDDDDDDCD:AACDDDDDCCC@
@3GB
GGAATGGCTGGGGGGGTCTCACGTGGCCCCGGGGGAGGGAGGGGGGAAAGAAGGGGAAGAAGGGCAGCAGGAGGAGGGGGAAGGGATGAATGCAGAGGG
+
00-2(..6)-((5@36&&(((((2(2&(+&&&&&&&&)&)6&&&5&&&(+((3(07/7<(+86526&((+(+80((0&)5&)((02(((((((((((+&
@3GC
GGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATC
+
@@@DDDDDDHHFFIGGGI?=9GBFBFHGIIIIIIHIIIDHGHIIBHGGGHGGGGIIII7@CHFHFEBDCCC@CBBBCCCCCCBBB>@CCCCCCCCCBBCAA
@3GD
AGCGGCAGCTCAGCTTGGACATCAACAAGCTCCCCGGCGAGAAGCTGGGCCGCGTGGTGCACATCATCCAGTCACGGGAGCCCTCCCTGAAGAATTCCAAC
+
@@@DFFFDFBFHDGJGHJEFECGIGIIGGICGEBD@A:5@EE6CD;?CC?C8?B9<B(<:>C>CCDDDC@ACA::0>B59@BD9ABDC@9>>4?CCCDCDC
@3GE
GAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCTAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGC
+
CBCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJ4BGIJJJJJJJJJHHFFFFDDEEDDDBCDEDDDDDDDDDDDDDDDDDDDDDDDDDDDDD
@3GF
TCGAAACTGATATAGTACAACGAATGGAACAAGAAACACAAAGAAAGTTAGAACAACTCCGGGCAGAGCTGGATGAGATGTATGGGCAGCAGATAGTGCA
+
@@@FFDAEDDFHHHDEHIIJHBGGGEIIGGDIIJGIIJGFHIHGIJFDFGEGHIIEHICCCE@BEBDFFCCE2>@C;C@C;A;AC??CBBDBDDDCCCCC
@3GG
CAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCAC
+
@@@DDAD?FFDBHGEGFHGIIIFGGG>GHIIGGGIIGIEGGAHGHEI9FG@FHGDGGHFFEDFF@CECECCCBBBBCCCCCCCCCCCCCCCCCCCBCBBBB
@3GH
CTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTAC
+
CCCFFFFFHHHHHJJJJJJJJJJJIJJJJJJJJJHHJJJJJJJJJJJJJJJJHHHHHHFFFFFFDEECCDDEDDDDEDDEDDDDDDDACDDDDDDDDDDDD
@3GI
GGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJBGHJJJJIJFIIJJJJJJIJHHHHHFFFFFFEEDDDDDDDDDCDDEDDDDDDD
@3GJ
CCCAGGCAGTTTTATGATGACACCTGTGTTGTCCCAGAAAAATTCGATGGAGACATCAAACAAGAGCCAGGAATGTATCGGGAAGGACCCACATACCAACG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJIJJJJHHHHFFF@DFFDDDDDDDDDDDDDDDDDDDDDD
@3GK
GCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATAC
+
@@@FFFFFHGHHGJIJIEHGIIJJGIIJFEGHIIJIIJCHGIIJIJJIJJJJJIIIJGFEHHHFFFFDEDEEDDDDDD3=:CCDCDCDDCCCDDDDDCDDD
@3GL
CTAGAAGCAGCCAAAGATGATTATCGAATACGTTGTGAAGAGTTAGAAAAGGAGATCTCTGAACTTCGGCAACAGAATGATGAACTGACCACTTTGGC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJHIIHIJJJJJGIJJJJJJJJJJIJJJJJJJJJJJJJJHHFFFFEEEEEEDEDDDDDDDDDDDDDDD
@3GM
ATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGT
+
@@@DFFFFFAHDCEBFFEGGHDDHGIIIIIGFHEHIIGEHCHGEEHGAFBBH@DCEHEHFFCEDD?==@>CC>>@CA@>>CB>CDDDC>C>ACA?A<?BD0
@3GN
CTCCTCCAAGATGAAGGGCTTCTCGTCCTCAGAGTCGGAGAGCTCCAGTGAGTCCAGCTCCTCTGACAGCGAAGACTCCGAAACAGGTCCTGCCTAATCAT
+
CCCDFFFFHHHHHIIGGEGEHHJEIIJJJJJJJJ@GGGBHIIGGIJJIG3=FFGGIAHIIHHHHHFFFFFDDDDDAACDDDDDDDDDDCDDDDDDDDDDDD
@3GO
TTCCCCTAGAGCAGCTGGGGAGAGGGACGATGTCTGTCTCAGCCCAGGAGTTTGGCTGAGCAGCGAGATGGATGCTGTAGGCTTGGAGCTGCCTGTACAA
+
8;?D;DDDD<D8+2C;+AF:3)):1?)):)8B848?09?D*B887==C(;=CA;A:?=(.77@(,',,5:3>>35(:55>A4(+57><><9((+:(4:>A
@3GP
CAAGGATATGCACAGACCACCCAGCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGC
+
CCCFFFFFGHHHHJJJJJJJJIJJJJJJJIJJJIJJIJJJJIJIIJJIJIJJIJIJIIIJIJIIHHHHFFFFFFEEEEEEDEDDDDDBDDDDDDDDDDDDD
@3GQ
CAAGGAAGAACTAGGACTAATTTTAGAAGAAAAGTGTGCTCTACAGAGACAGCTTGAAGACCTTGTTGAAGAATTGAGCTTTTCAAGGGAACAGATTC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJGHFGIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIHHHHHHFFFFFFEEDDDDDDDDDD
@3GR
CATAATTACATGCGGTAAATCTCATATTTTCTTCTGGACCTGGAGCGGCAATTCACTAACAAGAAAACAGGGAATTTTTGGGAAATATGAAAAGCCAAAAT
+
CCCFFFFFHHHHHJJHIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHHHFFFFFEDDDDDDDDDDDDDDDDDEEEEDDDDDDDDDD
@3GS
GTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCC
+
CBCFFFFFHHHHHJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJAHIHHHHHFFFBDEEEEECDEEDDDDDDDDDDDDDDDEDDDDDDDDDDD
@3GT
AACTGATTGAGCCTGAAGAGGTGGCCCGACGTTGGGGCATTCAGAAAAACAGGCCAGCTATGAACTATGATAAACTTAGCCGTTCACTCCGCTATTACTAT
+
@CCFFFFFHHHHHJJJGHIIJIJIJJJJJJJIIJJJJJIIJIJJJIIJIJHHHHFEBFEEEDEEDDDDDDADCDDDDDCDDBBD?CDCDCBDDBDDEDDE@
@3GU
TCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAA
+
CCCFFFFFDFBDFHFEG@HGGGGGHGIBDHGGGIICEGGIGD>GIGGHGHGEGHCBGIIIAHFFD<BCCECCCCCCCBCC?C<>CACCECC@:@CCCAB
@3GV
CTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCT
+
<?@DDDBDBDFHDGIIIIIIGEGGHIGGAGEFHHE>DCHHIGH?G@DDFGGHIEHGIIAD;7==DGIFFFB??BCCBBCCACDAC;:CA@CCCCCCCCCCA
@3GW
GGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTC
+
CCCFFFFFHHHHHJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJIJJJJJJHHHFFDDDDDEEEDDEDEDDDDDDDDDDDDDD
@3GX
AAAGGAGACAATCATTGAAGAATTAAACACAAAAATAATAGAAGAAGAAAAGAAAACTCTTGAGCTAAAGGATAAATTAACAACTGCTGATAAATTACTA
+
<1;1AAAADDF:<FBFF<A?4CHHH<A@<AEEGH9C@911:4BDGDD;?3?F?BF3==<BFH@A;=DGEE@9?>C=AB7;)7@A>66.>CC;ACCC;:;A
@3GY
CTGCCCTGGGCCTGTATACCGGATAATGACTCAGTGCTGGCAACATCAGCCTGAAGACAGGCCCAACTTTGCCATCATTTTGGAGAGGATTGAATACTGC
+
CCCFFFFFGHHHHJFHGIJJJIGHIIIIIIGIIGGHIIIJJJJJJIIJIIJIIJIIJJIJJJGHHHFEFFEEEDEECDEFEDDCCCDDDDDDDDDECDED
@3GZ
CAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTAC
+
@@@ADDFFFHAFHHCIIIICEGAHGDGCH@FHGC>FGHHGGHEHEHIIG>CFHGGDGHCEF,3=A>CC@BBBBB@BBBCCC>C@AC>@CCCBC>+:C@:@>
@3H0
GGAAACCTCAAGCTGAGAAAGTTGATGTGATTGCCGGCTCCTCCAAGATGAAGGGCTTCTCGTCCTCAGAGGCGGAGAGCTCCAGCGAGTCCAGCTCCTCT
+
??@?=DDDDFFFFF>AG:ACG<<A:,+<CA994<?:8@6609?09899/)88).-;F2@;7@-55;B?>B>((38'50(+>A@(+()059?3+>>@:4934
@3H1
AAAACCGAGTTGCAGTCCTGGAAAATCAAAATAAAACTCTAATAGAAGAGTTAAAAACTTTGAAGGATCTTTATTCCAATAAAAGTGTTTGATTCCTA
+
CCCFFFFFHHHHHJIHIJJIIJJJJJJJJJJJJJJJJJJJJJIIJJIJJIHGIJJJIIJJJJJJIJJJJJHHHHHGHHFFFFFFE>AEDEDDDDDEDD
@3H2
GGAAGACTCGATCCGCCTGCCTGCGCACCTGCGCTTGCAGCCAATTTACTGGAGCAGGGATGACGTAGCCCAGTGGCTCAAGTGGGCTGAAAATGAGTTTT
+
@<@DDDDAHD:C?FHD=FBGA@@3?FHE>BG>G0DGIIIG@AFE@@CH>EGH3AA?E?B1(5(6;5;;?@C25,::?A4>C@::@8(+5<A:@:A(44:>:
@3H3
CAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCT
+
??<BDAADDDDCCB>AEEFI9F3+A::?C?CDEDEDIEDDDDEIIC3B?B@2;CD;@AD>AAADADD@;>@>@????3;:>>>AA>A5>AAA?>(39>?>
@3H4
CTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTAT
+
CCCFFFFFHHHHHIJJJJJJJJIJGJJJIJJJGGIJJJJJJIJJIJJJJJJIJJIIJJJJIJJIGGHFFHGHHEFFFCEDEEDDCBBCBDDDDDDDDDDDD
@3H5
GAAATAACCAGTCATGAGCAGGGCTTCTCTGTGGAACTGGAAAGTGAAATTTCAACCACAGCAGATGACTGCAGTTCAGAGGTAAATGGTTGCAGTTTTGT
+
@@@FFFDFHHFFHIJHGIIJJFEGIIGJIIJHIGHGIGIJGIIJ?DGHIJJIJJIJIJJGGGIJHIJGIIIGCHHHHFFCFE>ACCEEE>@BDDDCDDCB9
@3H6
ATCAGATCCTGGGCCCGACCAGCAGTCGCCTAGCCAACCCTGGAAGCGGGCAGATCCAGCTGTGGCAATTCCTCCTGGAGCTGCTCTCCGACAGCGCCAAC
+
CCCFFFFFHHGGFHJJJJJJJJJJJHIJJIGIGIJJJIJJJIJJIIIHHFDDDDDDDDDDDDCDDDDDDDDDDDDDDCB@CACCCCCDDD5>BDDDBDDDB
@3H7
CCTCCTGTTTGCGGAAGAAAAGGAAACCTCAAGCTGAGAAAGTTGATGTGATTGCCGGCTCCTCCAAGATGAAGGGCTTCTCGTCCTCAGAGTCGGAGAGC
+
CCCFFFFDDFHHFIHJJGGIHIIIIJIJJJIJJJIIJIIJGHIIIJIJHIIIIJJJJIFEHFDEFEDEECDDDDDDDBDD>C@??BDDDCCD>CDD@D@BD
@3H8
CTGCAACCTATGAGCAGAACGCCTATGCAACTTCTTATGGACAACCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCC
+
0;3(().(2;)))2)=)8))(((2:)@><<>3=9<)6;11=):..=5><9?<???;>;;=?>8)8<):=76)9=39'3,25;3;;:;0:852287((++
@3H9
CATTAAGGAACGAATTTCATATACACCTCCAGAGAGCCCAGTGCCGAGTTACGCTTCCTCGACGCCACTTCATGTTCCAGTGCCTCGAGCGCTCAGGATGG
+
@@@FFFFFGGHHHJJJGHHDHHGIIHGIJJJEGIJJGIGGIGHDDH@FHGDHEEGEIGHGHGFFDDBDCCCACC@CCADDAAACDDBBBBBD?@@CCCDCD
@3HA
CCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGAT
+
@@<D;DDDFFBABGHBHIIIIIDEHBDHGIHGG<GIIGIGDEFDBFD>FGIIDHIIIIIB=;@F;CE;DAE?BDDEFCCEEC3@A>ACCCACCCBBB93?C
@3HB
CACTTCCCTTGTGGGAATGTCAATTACGGCTACCAGCAACAGGGCTTGCCCTTAGAAGCCGCTACTGCCCCTGGAGCTGGTCATTACGAGGATACCATTCT
+
CCCFFFFFHHHFHJJIIJJIJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJHHFFFEEEEDDDDDDDDDDDCDDDEEDDDDDDDDDDDDDEE
@3HC
CCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTTATGGG
+
@C@FDDEEBDFBFEEGBEEBHAEGIEIBHFGEFIIIIGIIIIIHIIIHGGHGGGGCEECCDC@>EAEDEBDC=ABDBD@BDDCC@>A:>AB9958?@@CCD
@3HD
TGAAGGTTCAGTTTCTAAAGTAAATAAAAGTTTTGGTGAAGAATCAAAAATAATGGTGGAAGATAAAGTTTCTTTTGAAAATATGACTGTTGGAGAAGAA
+
CCCFFF2AFHHHHJJJJJJJJJJJJJJJJJHIJJJJFHIJJJIJJJIJJJJJIJJJBFHHJJGGIJJJHIJIJJJJJHHHHFFGFFFFFFDEDEEDDDDD
@3HE
GACAAGTGCAAGCCTATGTCCTATGAGGAGAAGCGGCAGCTCAGCTTGGACATCAACAAGCTCCCCGGCGAGAAGCTGGGCCGCGTGGTGCACATCATCC
+
@CCFDFFFGHFFFIJIBHHIIIICFIGEADGIGHIGIIICDBBFGHHGGFHIGAHE;EEEAEEDEF>BBDDD@;CC@CDD??<>@59B(83@4:ACCDCC
@3HF
CAAGGATATGCACAGACCACCCAGCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGC
+
CCCFFFDDHFFFFIJGIJJIJJJJIJJIIGIIEIJIJIIJJJJGFHHIJIJJJGIIGHGGIEHGGHAEBC?CDBEEEEECCEDDDD@D@BBDD@CBDDDDD
@3HG
CCTACCCTCTGTCAGTGTCTCCCATGGAGAATAATCACTGCCCAGCGTCCTCCGAGTCCCACCCGAAGCCATCCAGCCCCCGGCAGGAGAGCACACGCGTG
+
@@@BDDDAFHBFDHGCECH<F<?;FFBAGHIIIDIBHIIGIGIIGHBFGGFBHIG8;C@GE=@HBDDBBACACBCCCBBBBB9@><>B<?BBABCBBB><@
@3HH
CTGTGTCACATGGTGTGAATGTCTCTTTTATTCAGGGGATTTGAAATAACAAGCCTCTTTCTAAAAAAGCTTTTTTTTTTTTCTCTTTTCTCTCTTTCCGC
+
@@@DBDDDHFHFH<ACB<CCGG@A?EFHDHCBGFHFEE?GFBGIHEEDHH?FFEGGIIIE=DGGEHGIFECFHHECBBB9>@(43:((4(+(((++4(((0
@3HI
GGAAAATGAGGACCTCAAACAACAATGTATTCAGCTAAATGAAGAGATTGAAAAGCAAAGGAACACTTTTTCATTTGCTGAAAAAAACTTTGAAGTTAACT
+
C@CFFFFFHHHHHJIJJJJJJJGIHIIHGIGGIIIIIIJJIJJIIJIGGGIJJIIIJJJIIIHIGIJJIJIJGHHGFEHHFFFFFDDDCDDDDDDDCDEAC
@3HJ
CGACAGAGCGGCGGCGGTGTCTGGCCAGGCGGTAGGCGCTGCCTGGCCGCGGCGGGGGAGATGTTCAGCGGAGAGGCGCTGGAGGGGGCGGGGCTGTGGG
+
???DDDDDDDDDDDIDD,5=A@A@3=>?????3::?A73&0)83+8285797&59<?&5)&(++:(((()&&)02((&&&&0+8()5>&)5&0&058>()
@3HK
CGACGAGATTGAAATCGACTTTGAGACCCTGAAGCCGTCCACACTGCGTGAGCTGGAGCGCTATGTCACCTCCTGTTTGCGGAAGAAAAGGAAACCTCA
+
@<<DD@D1<:CFDHG@C3CEEHH>?:C::?FD*?FDG:6@7B3;BG@F;/;??CC3@6@3>C883@>CA:>??CCCCCC>9@0-98?C<CB??9?@A<3
@3HL
CTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTT
+
C@@FFFFFHHFHHJJGGCHIHIIIJCHIJJJJGIIIIJJIJIIIFHGHIEEGIGIJIGIIJJIJJJJHHHHFFFFDDCEECEDDDDDC?CDBDDDDDDDCD
@3HM
TACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGGGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCT
+
?<??B;:+==<DDE>E@;C?8)13??D@BBD?D@@BBD8B9.8)'--573AA=?>7=(,4,.;>>;A;A>>>?55>:>,535>D((:>38<2<<??82<<A
@3HN
ATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACCAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCA
+
@@@DADDDBHBF?:EHDBIEEEHIGEIIGGIDEH@FHGI@BHIIIID@BGHHGHI'=@FHGCHGIIFFDFBEAECC>ACCCCCCCCBBCBBCCCCCC(>A
@3HO
GCCTTCCTACCATGCCCACCAGCAGAAGGTGAACTTTGTCCCTCCCCATCCATCCTCCATGCCTGTCACTTCCTCCAGCTTCTTTGGAGCCGCATCACAAT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJFHJJJJJJJIJJJIJJJJJJJJIJJJJJJJJJJJJJJJJJHHHHHHFFFFFEEEEEEDCDDDDDDDDDDDDD
@3HP
AAGTCGGAGAAGGGGTTGGAAGAGGGGTCTAAAGAAGAGGTGAGAAGGGGAGTGGGGAGGGGGGGGAGGGGGGTGGGGGGAGAAAGGGAGGGGGGGGGGC
+
11++++))))+++))2))11*?)1)0))))**0/0())(().)..))(''''(((('('''&&)0&&&&&&&&&0&&&&&&&&++58((&&)&)&&&&&&
@3HQ
ACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCC
+
CCCFFFFFHHHGHJJIJJJJJCFGIJJJJJJJJJJJJJJJJJJJJJJIIJJJHHEHHHFFFFFFEEEEEEDDDDCDDDDDDD@BDDDDDDDDDDDDDDD
@3HR
GCCATTTAAGGAGAGGGGGGGAGGAACCGCGGACAAAGGTTGGGACGCGAGGGGTAACTACACCTCCGAGCCGGCCCGAGAGGCCGGATGGGTCTGTTGAC
+
(-0:(2)2@@<<((((<(8)))&0(((+0&)0&)6((2+3((&&+()&&&)5&))&+22((+(3(++085&&&05-&)&)&&+(+)&&&)((((+(+286(
@3HS
AGGAGAAAAAGAAAAAGGAAGCAGAGGAAGAGGATGAGGAACTCTCCAACTTTGCTTACCTCTTGGCCTCTAAACTTAGCCTCTCACCAAGGGAGCATCCC
+
B@CFFFFFGGHHHJJJJJJJIJJJJJJJJGIJJHGGJJJGHIJIIEGIJJGIIGGHIIIGIIIJGHHDHFFFFFFEEDECDDDDCCDDDDDDDDDDDDDDD
@3HT
AGCCATTCAAGAGCTGATGAGTAAAGAATCTCCTGTCTCTGCTGGAAATGATGCCTATGTTGACCTTGATCGTCAGCTGAAGAAAACT
+
CCCFFFFFHHHHHIJJJJJJJHIJJJIJJJJJJJJIJJJJIJJJJJJJJJJIJJJJJJJJIIJJJJJIJJJIIJJJIJHHHHHFFFFF
@3HU
TGAAGAGCTTGATTTGCAAAGAATAAATCCAACTACAGGGAAAATGAAAAGTTCTGTCTTTGATGAAAACAAAACTTTTGTAGCAGAAACATTGGAAATGG
+
0(((2)(:2@..=@@8@14.61().9.>66>?)>))).)(1:?))<)<>??6=??1>>?@17)).)>.;);3>?063:?1=8=1.=(.:(..54;(5--38
@3HV
GTTGAATGTGACAGCACCTACACCTCAGCAGTTACAAGCCTTCAAAAATGAAGTAGGAGTACTCAGGAAAACACGACATGTGAATATCCTACTCTTCATGG
+
C@CFFFFFHHGHHJJJJJJJJJJJJJJJJJJIJJJJJIJJJJJJJJJJIJJJJJJJJIJHIJIJJJJJJJJJJHHFFDDECEEEEEEFEEDDDDDDDEEDD
@3HW
GGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJIJIJJJJJJJJJJJJJJJJHHHHHHFFFFDEDEDDDDDDDDDDDDDDDDDDDDDDDDDDDDDD
@3HX
ACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGT
+
@@@FFFEDFBFFDFEGHHBH@GGGIIEHHIIIIBE?CHGBD>BBFGGIIDIGHIIFEIG@EEEFFAC@CEFFFCA<@@BBBB<A??>BBCC@>CCCBC355
@3HY
CCAGCAGAACAGAAGGCTGTATGTTTGAAAAGGGCCCCAGGCAGTTTTATGATGACACCTGTGTTGTCCCAGAAAAATTCGATGGAGACATCAAACAAG
+
@CCFFFFFHHHHHGIJGHIIIGGEEHJJJIJGGIEIJIJIIIIJEHIJIIIGIIJGIIIJIDHGEEAEHEDFDEFEEECEDEDDDD<ABCACDCDC@BC
@3HZ
AGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACT
+
@@@FFFFFHHHGHHIJJJJJIIHIIIIJJJJJJJJIJJJIJIICGIJJJIJJJGJJGHGHFFFFDEEDCED?BB?CCDCDDDDDDDDDCCDDDDDDDDDDD
@3I0
ACAGACTGTGTGAAATGCCTTGCTATACATCCTGACAAAATTAGGATTGCAACTGGACAGATAGCTGGCGTGGATAAAGATGGAAGGCCTCTACAACCCC
+
CCCFFFFFHHHHHJJIIJIGIIIJJJJJIJJJIJJJJIJIGGIGFIGHIFHIJJJIHEGJJGJJJJIIJJAEHDCEFFFEEDEEEDDDDDDDCDDDDDDD
@3I1
CAAAAGGCTGTGTCTACTTGGAACGGATGCATTTCATTCACAGGGATCTGGCAGCTAGAAATTGCCTTGTTTCCGTGAAAGACTATACCAGTCCACGGAT
+
?@?DDDDD<D<CD<F:CFCHAAFHG<EG@E<D@FI*9DH4?BD;FHII3BB*9BBFEG;7=FF=@EGC=CEE;EB;?B=C;;AACA>>>CCCC(,55;=>
@3I2
CCTGTGTGTAGATATTTCAAAAGGCTGTGTCTACTTGGAACGGATGCATTTCATTCACAGGGATCTGGCAGCTAGAAAGTGCCTTGTTTCCGTGAAAGACT
+
+1++?7A>+<A<A4A>B<>?<+7=7<77+2<?<A9AA9@?3=)?==BAA7=A?A/9=)=7=<AA<=))77;77)3=>?)7.;@@>>;>=35;5(,599>==
@3I3
AAGGGAAGGACGTCCTATGTACCAACGCCAGATGTCTGAGCCAAACATCCCCTTCCCACCACAAGGCTTTAAGCAGGAGTACCACGACCCAGTGTATGAAC
+
+:=+<++<+2?=<?CACCB7@4A<<5)014?5?AB<A?<?A;A38==<37.;>==AAB(-=(;=@<(;>;=;5-;>=85((5999,&&))22++888:?88
@3I4
CACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGAC
+
CCCFFFFFHHHHGJJJJJJJIJJJJJJJJJJIJJJJIJJJJIJJJJJIJJJIJJJJIJJJIGJJJJIHHHHHFFFEEDEEDDDDDDDDDDDDDDDDDDDDD
@3I5
GGCAGTTTTATGATGACACCTGTGCTGTCCCAGAAAAATTCGATGGAGACATCAAACAAGAGCCAGGAATGTATCGGGAAGGACCCACATACCAACGGCT
+
===7<;>@,2<AC,,<3ABA;@C=+3++<?AA@1?>))1:750??AB)0))97<?B==2))().8(====)).)75'''3(;(;5;98=:9(55(28;=&
@3I6
CCAACTACTGCTTTGCTGGCAAGACCTCCTCCATCAGTGACCTGAAGGAGGTGCCGCGGAAAAACATCACCCTCATTCGGGGTCTGGGCCATGGCGCCTTT
+
?=1D?DDDDFAA:E9E<C?F:3<A32AF8:?EB9*111:?GGII;F90))((08BFFA<B99;?',;;>@@<?B2@;AD8&5))(33<<<(3(+()&)99@
@3I7
CAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTTATGGGCAGG
+
@@@BDDDBFDFFHJIJIGIJJJEHEHCGBHGEHGEHGFDD>F<??@AGBD@CGD=@GGGGCHGEHE>AC?;AB@DBBDCACCD@@<A+5<BCDDDDDDCBD
@3I8
GTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGC
+
C@@FFFFFGHHFDHJFHDJFJJJIJJJJJGIGIJGIJGHEFGIIGIGFIGIIIJIIGGGGIIEFEFE?CFCEDEDEEEEEDDDDDDCCDDDDDCBDDDD
@3I9
GAAATCTTTTCTCTTGGATATATGCCATACCCCAGCAAAAGCAACCAGGAAGTTCTGGAGTTTGTCACCAGTGGAGGCCGGATGGACCCACCCAAGAACTG
+
=;+<?A4A=7AC=2,<CBBAA?,333+3?;@+2?;;;?BBB9A9AB1AA:2=BB4>=<75ABB4A777A;A>>9).(;;=@====??==:=;;<<8288::
@3IA
CACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATG
+
C@@FFFDFHHHHHJJJJJJJJIJJJJJJJIJJJJJIJJJJJJJJJJJJJIJJJIJIJJJJIJJJHIIJJHHGHHHFFFFFECEEDBDDDDDCDDDDDDDDD
@3IB
CCTGAACCCCCGGCACTCCGTGGATTTCAAACAGTCCAGGCTCTCCGAGGACGGGCTGCATAGGGAAGGGAAGCCCATCAACCTCTCTCATCGGGAAGACC
+
??@DD??AFD<FAG:E9:B;DF@1B<FDEB>DF3B9C@DF28;9@A;8BB>;9@6@B68?:A>A8((+2&8?7122<A(4>38A<(9>>@>@AB<<B@(93
@3IC
CCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATAC
+
CCCFFFFFHHHHHJJJJJJJJJJJJIJIJJJIIJJJIJJJJJJJJJJJIJJJJIJJIJIHHHHFFFFEEEEEDDEDEDDDDDDDDDDDDDDDDDDDDDDDD
@3ID
GGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCAC
+
@@@DABDDAHD>BDEEDGIGGGFIIIIIGGGIIIIIIGGGIIGGD><FHIHIIGEEHIBG@GGCEHC>CDFDCDCCCDDACCDDDCDDDD:A?ABAD?BDD
@3IE
CTTTGAGAGCTGGATGCACCATTGGCTCCTGTTTGAAATGAGCAGGCACTCCTTGGAGCAAAAGCCCACTGACGCTCCACCGAAAGATGATTTTTGG
+
1::2A@;2?7=;A<C+?+A77<+32?A<?:?1:@A9B4:?:??7:;A2A9/9<>=A7.).>A9;((.6A;>)7<@<</;(,3628;;(3:(+3+35.
@3IF
CTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJHIJJJJJJJHIJJJJJJIJJJJJJJJJJJHHHFFFFEEDDEDDDDDEEDDDDDDDDDDDDDDDDDDDD
@3IG
GAGAAAACTAATGCGCTATTCACAAGAGTTAAACACTCAGTGGGGGGGGGGGCCACGAGAGAGGAGAGGTGGGGGTGGTGTGGGGTGGGGGGCGTCCTGGG
+
((((()22))2)))2(--())))2)()().)2)22(1))))).((.&&&&&&&&+(&&&)&(((+((+((((0)&)&&)(+((5-00&0)&&&&)&)++3+
@3IH
CCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAAC
+
CCCFFFFFHFBHDGIIDHIIIJJIGGIGHIHGIHGIFGBHEGGFGBHHHJIGIIJJJ<FGIIIJEFHHFFECFFECEEDC@;ACCCDDCCCDACDDBCCD
@3II
GCTCAAGGAAAAGTACTGCAAGCAACAGTAGTCGATGTTGAATCGGGTTCTAAAGGAACGGGCGGAGAGATACCACTGGTTAGCGTAAAAGTTGGCGATA
+
(005@?<51;1>?12)).36))(3;7(3;<19)((()231)0))0(50(069>3:)(.('-3'55;,;75/(+(++((+66:<(08((+((+3(::5-&0
@3IJ
GAAAGAGTTTCTTTTCCTGCAATTGAGACAGCACTGGTATGACTTGGTTTTCTGTTTGCACCACTTCCATTGGTTATACAGGACATGGGAATGACTGCTCG
+
@?@FADDEHHADHEEHGGGIEGIDGEGGII9;CEGGI?DFHEGGIII@FGIDIGIJIBEHIHHHGIGIGJJJI>EEH).7==BDFFEEDCAB-->A@?A>?
@3IK
CTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAA
+
CCCFFFFFHHHHHJJJJJHIIJIJJJJJIGJJJHIIIIJJJJCGGGJJDIJJJJJIEDGHICHEEEFDEEEDCDDDDDDDDBDBDDDDDDDD(+>@CCCD
@3IL
GAGTAGGCCTGGCTAATGCCTGCTATGCAATACATACTCTTCCAACCCAAGAGGAGATTGAAAATCTTCCTGCCTTCCCTCGGGAAAAACTGACTCTGCGT
+
@@?DDD?DF?CBDCFBF>CF:<?:FHFEBB?FEHBFB?GDDGBGEHE<???B?DDF@8BC;CF7@EH=7@E>>E7??DEB@A<;BBBC?@A@::>@::>0)
@3IM
GTCTGAGCCAAACATCCCCTTCCCACCACAAGGCTTTAAGCAGGAGTACCACGACCCAGTGTATGAACACAACACCATGGTTGGCAGTGCGGCCAGCCAA
+
@@@DDEFFGHFGHJJGGIDGIIGIIJIJJJJGGIJJJIJEHIEHGI?BDEFFGIJEHFHECHEFDCEDFCCDDBDDDCCDCC?=CDBDDDDDDDBBBDAC
@3IN
TAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGA
+
??:BDD>AFFDFBGGBHA@DEF?DGEGDDFBBB<BDBGHB@FGIEIIII=?AEDFFEB>C;A@DCCAABB?BBCCCCC?@>ACCBBCC<AABCCCCC@CC
@3IO
CACGACCCAGTGTATGAACACAACACCATGGTTGGCAGTGCGGCCAGCCAAAGCTTTCCCCCTCCTCTGATGATTAAACAGGAACCCAGAGATTTTGCAT
+
BCCFFFFFHHFHHJJJJJJJJJJIIJJJJJICGHIIJGHGIJIIJIIJJHHHHHFFFFFFEDDDDDDDDCDDDFFDDDCDDDBDDDDDDBDDCDDDDDDD
@3IP
CTGACATCTCCTACATGCCTTCCTACCATGCCCACCAGCAGAAGGTGAACTTTGTCCCTCCCCATCCATCCTCCATGCCTGTCACTTCCTCCAGCTTCTTT
+
@@CDBEFDDHFHHIIJJJGHJIJIJJIJIJIIIJIJJGIGHIIIH?BEHGGIJIIJGBDHJJIIJIJJIGEHHHBB@DFEEEEDEDEDDCDDCACCDCDDD
@3IQ
ACACCATCCAGCACGCCAGTGTCCCCACTGCATCATGCATCTCCAAACTCAACTCATACACCGAAACCTGACCGGGCCTTCCCAGCTCACCTCCCTCCATC
+
CCCFFFFFHHHHHJEGIGJGIHIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIIIJJJJJHHFFFFEEEDDDDDDDDDDDDDDDDDDDDDDDDDDDD
@3IR
CACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGAT
+
CCCFFFFFGHHHHJJJJIJJJJJJJJJJJJJJJJJJGHIIJJJJJGHHIIJJJHIJIJJJJIHHHHFFFFDDEEDDDDDDDDEEDDDDDDDDDDDDDDDDD
@3IS
CATAATTACATGCGGTAAATCTCATATTTTCTTCTGGACCTGGAGCGGCAATTCACTAACAAGAAAACAGGGAATTTTTGGGAAATATGAAAAGCCAAAAT
+
CCCFFFFFHGHGHJJHIJJJIJJJIJJJJJJJJJIJJJJJJIJJJJIJJJIIJHJJJJJHHHHHFFFFEEDDDDDDDDDDDDDDDDDEEEEDDDDDDDDDD
@3IT
GAAAAATTCGATGGAGACATCAAACAAGAGCCAGGAATGTATCGGGAAGGACCCACATACCAACGGCGAGGATCACTTCAGCTCTGGCAGTTTTTGGTAGC
+
C@@DDDFFGHHDFEFHEHEGHGEEBGGIGF;?EFGGGHI?FFFGGBDAHI>=@FEHGHC>AA=?DFBBDDB>CCACCCCA>@>@CDDC?B3:A@?@DACDC
@3IU
GTTATTCCCATGTCCTGTATAACCAATGGAAGTGGTGCAAACAGAAAACCAAGTCATACCAGTGCTGTCTCAATTGCAGGAAAAGAAACTCTTTCATCTGC
+
C@CFFFFFHHHHHJJJJIIJJJJJJJJJJIJJHIJFGGIJJIJJJIJJIJJJJIIIJJJJIJHHIJJIJJJIIJJJFHHHFFFFFDEEEEDDDDDDEEDDD
@3IV
ATCCTGAACCCCCGGCACTCCGTGGATTTCAAACAGTCCAGGCTCTCCGAGGACGGGCTGCATAGGGAAGGGAAGCCCATCAACCTCTCTCATCGGGA
+
B@CFFFFFHHHHHJIIJJJJJJHIJJJGIHGGIIJJJJGIJJJJJGIJJHGFFD>BDBBDBCCDDDDDDDDDDDDDDDDDDDDDDDDCCDDDEDCDD@
@3IW
CATCAACAAGCTCCCCGGCGAGAAGCTGGGCCGCGTGGTGCACATCATCCAGTCACGGGAGCCCTCCCTGAAGAATTCCAACCCCGACGAGATTGAAATCG
+
@CCFFFDFGHHHHGIJGHGGIGIIGIIIIIGGGIGBECCCDDDDDDDDDDDDDDDDDDDBDDDDDDDDDDDDDDDDDDDEDDDDDDBB@B@DDDCCDCCDD
@3IX
AGGAGAAGCGGCAGCTCAGCTTGGACATCAACAAGCTCCCCGGCGAGAAGCTGGGCCGCGTGGTGCACATCATCCAGTCACGGGAGCCCTCCCTGAAGAAT
+
CCCFFFFFHHHHHJJIJJJJJJJJIJJJJJJJJJJJJJJJJJIJHFDCDDDDDDDDDDDDBDD8?CDDDDDDDDDDDDDDDDDDBDDDDDDDDDDDDDDDD
@3IY
CGAGCAGCTTGCAGCCCTCTCTCAGCCCCAGCAGAACAAACCAAAGAAAAAGGAGAAAGACAAGAAGGAAAAGAAAAAAGAAAAGCACAAAAGGAAAGAGG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJIJJJJHHHHHFFFFFEEEEDDDDDDDDDDDDDDDDDDDDDDDDDDDDD
@3IZ
CATAATTACATGCGGTAAATCTCATATTTTCTTCTGGACCTGGAGCGGCAATTCACTAACAAGAAAACAGGGAATTTTTGGGAAATATGAAAAGCCAAAAT
+
CCCFFFFFHHHHHIJHHJIJIJJJJJJJJJIJJJJIJJJJJJJJIJJJJJJJJJJJIJJGHHFHFFFD?CDDDDDDDDDDDDBDDDCEDEEDDDDDDDDDC
@3J0
GTCATGCTTATATGGAGCAAAACTACTGTAGAGCCCACACCTGGGAAAGGACCTAAAGGTGTATATCAAATCAGCAAACAAATCAAAGCTCATGATGGC
+
@@@DDFFFHHGFHHHIGGIJJGGEHIHGIJIIJJIJCGGEHGHIJHGGGIIJIIGIEHH)==CFEGIIIJGEEHDFFDDDBBEEDEDCDACCDDCDDDD
@3J1
CAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGG
+
CCCFFFFFHHGHHIJJJJJJJJIJJJJIJIJIJJJJJJIJJJIIIJJJJJJJJJJJJJJJJJJHHHFFEFFFFEEFDDDDDDDBDDDDDBBDACCCDEDDD
@3J2
AGCCTTTAGCAGTGCCCTGGGAAGGTTCTTCAGGAGCCATGAGGGGCGAAGACAGAGGAACCCCCATGGTTTAGAGTTATGATAAGAATCCTTCCCCT
+
7;(-;16;)):))6:44)((-.;(9);).2)):33(<(9=<)6)13(-''',):==03(,;5''33;6;(+((++(5((62:</:((22(36/6(((+
@3J3
CAGCTGCAGACTTACTACAAGCCAAACAACAGATCCTCACTCATCAACAGCAGCTTGAAGAACAAGACCACTTATTAGAAGATTATCAGAAAAAGAAAGA
+
@@@FFDFFHGHGHIGIJJIJIIJJIIIIJIJGHGG@GHIGIJCHEHGGIGGGIFGGGHCGIJHIIIGDE?EAE?DEFFFDA@CCEECECCCDDDDDDDAC
@3J4
AAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGGGCTTACACCGCCCAGCCCACTCAAGGATATGC
+
;??BBD3=D:CFCEFFBEABCAEEADFGCG<???DFFDBGFDEFE1CCA@FF;@BA>@;;9?>?9AA(5???:@AB<-9<9>?BB7<B?9>A@@<4:>A3
@3J5
TGAAGAGCAAGCCCCCTCCCACGTATGAGTCGGAGGAAGAGGACAAGTGCAAGCCTATGTCCTATGAGGAGAAGCGGCAGCTCAGCTTGGACATCAACA
+
@@@DD?DDDHHHHGHGIGDEGFG):?FGE<?DGHHI@?CHIEHIIG..7=77==;?@CC>;CCCCC>CA@=??CCB@BBB@CCCCCC:?@>@>C>@@CC
@3J6
CAAACTCCAGAAAGCAAGAATGCTACTCCCACCAAAAGCATAAAACGACCATCACCAGCTGAAAAGTCACATAATTCTTGGGAAAATTCAGATGATAGCCG
+
=?;A?DB?FH?;CC@CB???HF<:<9CA;B@?8CGIDE?GHDHB<F66?A;=@FC@C@EH@;A???C:@??3;AAC>@@@@=B>BC@CAC>C:@CEDCCC<
@3J7
CTTTGCGCAACTTCCCCTATCATAGAGGAACTTATCCCCTTACATGATCAGGTCCTCATAAGCATATTCCTTATCTGCTGGCTAATGCTGTAGGCCAAAAT
+
0-0((2050(())).)@2(::<.6)))(2(.2).)0.9=<1))9)039>)))..)/.6/<3).;)89;>=8).8))..):(,..((-(--(-(,(7,,(((
@3J8
CGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGG
+
@C@FFFFFHHHHHJJJJGIJJJJJJJJJGJJJIJIJJJJJJJJJIIJJJJJJJJJJJJJJIJJHHHHHFFFFDCEEEEDDDDCDDDDDDDCDDDDDDDDDD
@3J9
CAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGG
+
?@?DDBDDHDHDDEHIIDEFGGDAHGDDGIDH>?3FHC@@<FGFDGHHIIEDC?2=BFGIGC@GIDC3?=C?AHEE3==>ABBBC@CCCDCC?C>>AACCC
@3JA
CGAGTTCAGCAACAAGAAGATGAAATCACTGTGCTAAAGGCGGCTTTGGCTGATGTTTTGAGGCGTCTTGCAATCTCTGAAGATCATGTGGCCTCAGTGA
+
BC@FDFFFHHHHHJJJJJJJJJJJJJJJJJJIIIIJJJIJJIJJJJIJJJIIGIHEHHHHEFFDDDDDDDDDDDDDDEDDDDDDDDDD>CDDDDDDDCCC
@3JB
AGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACC
+
@@@ADDDB3A@0?:AAEGI8???GGFCFF>CBFD9FFFECEFFEFB@FF@EEC2>5;@BD@>@@ACCBBBA3;@;5?22<<@<@BA>A8>AA@AA>A@B??
@3JC
AGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAA
+
BCBFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJIIJJJJJJJJJIJIHHHHFFFFEEEEEDDDDDDEDDDDDDDDDDDDDDDDDDEDDDDDDDD
@3JD
GAAAAAGAAAGAAGACTTCACAATGCAAATTAGTTTCTTGCAAGAGAAAATTAAAGTATATGAAATGGAACAAGATAAAAAAGTAGAAAACTCAAATAA
+
@@@DFFFFFDHDHIIJGGJIIIJIIGHIIGEIIGIHFHGHFGIGDGGHGIJJHGJIFGGIIIJIJJIJGIGIGGDGHEHFEFD;@CEEDCCCDDDDDDD
@3JE
CTTCGGCAACAGAATGATGAACTGACCACTTTGGCAGATGAAGCTCAGTCTCTGAAAGATGAGATCGACGTGCTGAGACATTCTTCTGATAAAGTATCTA
+
@@??D>ADHHGHH@AFFHGGDHEBHBBGHIIIIIGGGGHIIIIICHIGBCHCGEGIIGIIIHGEGGIAHHBE?=CEACCCCCCDEDDDEECDDABCFCDF
@3JF
GCAGTGTGTTCACACTTTGTCAGATGAGAAATGGGATGTTATTAACTGGAGGAGGGAAAGACAGAAAAATAATTCTGTGGGATCATGATCTGAATCCTGA
+
CCCFFDDDHHHHHJJJJJIHJJGHHIBHHIJIIIJHJJJJIJJJJJJJJCHIDFHGIJJJJJJJJJJHGHGHGFFFF@DECDEDDDACDDDDDDDDDDDD
@3JG
CCTACACCTCAGCAGTTACAAGCCTTCAAAAATGAAGTAGGAGTACTCAGGAAAACACGACATGTGAATATCCTACTCTTCATGGGCTATTCCACAAAGCC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJGHIJIJHIIJIJJJJJJIIJIJJIJIJHJHHGHHHHFFFFFFEEEEEEDDDDDDEEFDDDDDD@
@3JH
CTCAGCGACACTACCTGGGCCATACAGACTGTGTGAAATGCCTTGCTATACATCCTGACAAAATTAGGATTGCAACTGGACAGATAGCTGGCGTGGATAA
+
CC@DFFFFHHHHGJFIJJIJIJJIGIIGIIJHIHHGIJIJJIIJIJIJIJIIIJJJJJJJJJIIHHHHHHFFFFFFEEDEBDDDCCCDDDDBDDDDDDED
@3JI
TGCAGTTCAGAGGTAAATGGTTGCAGTTTTGTGATGAGAACAGGAAAGCCTACAAATTTATTAAGGGAAGAAGAATTTGGTGTTGATGATTCTTATTCTG
+
CCCFDFFFFHHHFEEFHIIGEHGIJHFEIIIIJGIIIJIIIGGGHIJIJJJIIJJJJJIGIIHHJJIGCGGIJHEFHHHF?BBDBCCEEFEEDEDDEDFE
@3JJ
AAACCAAGTCATACCAGTGCTGTCTCAATTGCAGGAAAAGAAACTCTTTCATCTGCTGCTAAAAGCGGTACAGAAAAAAAGAAAGAAAAACCACAAGGAC
+
==??D??:22A4<<:<EEDF?<333<CBF??<<:11:??910)B9:0BB?90??B<9<B?BEIB=(--'-:77.==).333(55>35==90(++2<??8>
@3JK
CTGAAAGATGAGATCGACGTGCTGAGACATTCTTCTGATAAAGTATCTAAACTAGAAGGTCAAGTAGAATCTTATAAAAAGAAGCTAGAAGACCTTGGTG
+
CCCFFFFFHHHHHJJJJJJIIJJJJJJJJIJJJJIJJIJJJJJIJJJJJJJJIJJJJJJFHIJJFHIJJJJJJHHHHHHFFFFEEEEEDDDDDDDDDDAB
@3JL
GAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGAT
+
BB@FFFFFHHHHHJJJGJIHIJJJJJJJHIJJJJJJJJJJJJJIJJJJJJJJJJIJHHFFDEEDDDDDCDDDDDEDCDDDDDDDDDDDDDDDDDDDDDBD
@3JM
GAAAAACAGGCCAGCTATGAACTATGATAAACTTAGCCGTTCACTCCGCTATTACTATGAGAAAGGAATTATGCAAAAGGTGGCTGGAGAGAGATATGTCT
+
???DD;DD?AFF;FEBBGFFHHCBCHEEHI4FHGCGF3DFFBH<GHIAED@GICH@C;CDCD=@ECA;=CEE;.;?C>>A.;?B=@B9?><BB15:ACCDD
@3JN
CTTACAGAAATCTCCAGGACCTCAGCGAGAAAGGAAGTCATCTTCATCCTCAGAAGACAGGAATCGAATGAAAACACTTGGTAGACGGGACTCGAGTGATG
+
CCCFFFFFHHHHHJEHIIIIIIII>FGIGHIIJJJIJGJJGGIJJJGIIJHIGIJIJJJIIIGEGIFHHEHFFFFFDEECDAA@CDBBDDDDDDBD@BACD
@3JO
CAGTACGCCCCGAGGGTCCTGACGCAGGCTTCCAACCCCGTCGTCTGCACGCAGCCCAAATCCCCATCCAGCACGCCAGTGTCCCCACTGCATCATGCATC
+
=??=ABD10<@DA@CECD?DBDDDIIIIIIDCDDECADIIDDD??;>;@A=9>;?9????>>>A??<>?>>A?>&9<??4:>AAA?>?2:>AAAA>AA>A>
@3JP
CACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGAC
+
@<<DDDB=DBHFFBGEEEG>@FH>4:33EFE9DBCFGDG@BAFGB9BBDFDGHCF<@CGIGCEDEA@7=>C=<=6;;AB>,=;A@<CCCCC:>?AC:>@CC
@3JQ
CAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCC
+
@@@DDDDDDFFBFGFDB9CG@CEEHIGEGG@FHD@GHHGEGDGCC=BFCHG@@88@EHGGGAE37?@@D@76;@8??;??5?A??AB?:;>A@C9:<>@B
@3JR
CCTACTCTTCATGGGCTATTCCACAAAGCCACAACTGGCTATTGTTACCCAGTGGTGTGAGGGCTCCAGCTTGTATCACCATCTCCATATCATTGAGACC
+
111==:=DAD<2<+C;EEII@:<:3AF3<F+C?:8?:9:9*0?9DDE9?3*/009D;C=87.-'@@@=CDDDD6;;;)7666;3>A;;A>3>;;AA:9>8
@3JS
CTTTTTCATTTGCTGAAAAAAACTTTGAAGTTAACTATCAAGAGTTACAAGAGGAGTATGCTTGCCTTCTCAAAGTAAAAGATGATTTAGAAGACAGTAA
+
@@@DDFFFHHDABG>FGEGGIIIIEG?FHGFGECFFGDFIGHIGIEHGG>FDBGEIHAF>CHIGFGECC>EEHBD;@DDF;?CAC>CDCCCFCC?C?:>@
@3JT
CAACAAGCTCCCCGGCGAGAAGCTGGGCCGCGTGGTGCACATCATCCAGTCACGGGAGCCCTCCCTGAAGAATTCCAACCCCGACGAGATTGAAATCGACT
+
CCCFFFFFHHHHHJJJJJJJJIJJJIJJJJJJEFFBCEEEEDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDEDDDDDDDDDDDDDDDDDDDDDBDD
@3JU
CAAGGTCATTGTCAAAGTCAAGACAGAAGGGGGGTCAGCTGAGCCCTCTCAAACTCAGAACTTTATCCTTACTCAGACTGCCCTCAATTCGACTGCCCCGG
+
@@@BDBDDFD<,<CGD>AEIHBEECE>FCCE6)5)6?CCCCCBC><<0<>CCCC@:@>@C?:ACC@C::@C>CCCC>>ACCCBCBBACCCBD?@BCABB>B
@3JV
CAGCAATCAGGTGGTCGTACAAACTGCATCAGGAGATATGCAAACATATCAGATCCGAACTACACCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATG
+
@CCFFFFFHHHDFFHHJGEGCEHGEIIJIJJGFGHGGIGHGIGGIGGGIJJJGGIGHJ?H@GCHGHHFGGFFDECCEEECCCCCCDDDDBDDDDDCDDCD
@3JW
CCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGG
+
@CCFFFFFHHGFHIJJJJCHGIIEHIJJJJGIJJJJIIJIIIIIJGGIIJJIJJGIDAHGIIHGGGGHFFFFEDEECACDDDD>CCDDDDDDDDDDDDDDD
@3JX
CTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGT
+
@CCFFFFFHHGGHJIJJJJJJJJJIJIJIIIIJIEGGHGIJJIIGIIJJJJJJIJJJIIGIJIJIJGHFHFDDDDDCDDDDDDDDCDDDBDDDDDDDDDCA
@3JY
TGCAAATACCATAATTACATGCGGTAAATCTCATATTTTCTTCTGGAACTGGAGCGGCAATTCACTAACAAGAAAACAGGGAATTTTTGGGAAATATGAA
+
:?;DDDA?F>?<FGA:C<<AC+@1C@F4*?1:E941111119*:0*:*00**998-'-54.7..)7?B@B366;>9((,5(,5?>5@B8=>2><A4:4(:
@3JZ
GGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTC
+
@@@FFADFHHFFGIHIJJFIHFHHIJHIGIJIJJIJIIICHIJIGIIJJJJJIEIJIIIAEGHEHFHHGFFFFDBECCCCDDDDACC@=?BBD?BDCDCDC
@3K0
GACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTG
+
:8=;BDDBF3:CA;C:C33E3)A3F:1C):*?:B9?DFBDFF4?888=(;()=FEEE@;?=?A7;?);@D3;>>CA?;;?@;B<???@4>@:::?8<@?<8
@3K1
CTTCAGCATATTCTGAAGCAGAGGAAACCTCGGATTCTTTTTTCACCATTCTTCCACCCTGGAAACGCTATACACACACAGCCGGAGGTCATACTGCATC
+
@@CFFFFFHGFGHJIGIJIGIEHIGEEHJIIHHFHIJGIJJJIIIJIIIJGGIIJIGIIIIGJIHH5<BFDDEEEE@DBDDBDDD>BD?CDDEDDEDDDD
@3K2
AAAAAAGTAGAAAACTCAAATAAAGAAGAAATACAGGAAAAGGAGACAATCATTGAAGAATTAAACACAAAAATAATAGAAGAAGAAAAGAAAACTCTTG
+
;?@DDD?DC?:CFFF<CFG?A??<@<EBGEFAFCG@DG?FFFFFE?DFE<CEEFCIGAF@@=DFFFI=ACEDDBDBADCCC;?A>BBBB3<B??:3>@BB
@3K3
GTTTACAGAATGAAATGAGTCAAAAGATAGAAACCATGCAGTTTGAAAAGGACAATTTGATAACTAAGCAGAATCAATTAATTTTGGAAATTTCAAAGCT
+
CCCFFFFFHHHHHJJJJJJJHIJIJJJJIHIJJJJJJJJJJJIIJIJJJIJJJJJJJJJIJJJIJJJJJHHIJIJJHHFHGHHFFFFFEEEEEEEDDDDD
@3K4
GAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGAC
+
@@@BDFFDFDDDDHIFIGIIHHGGEGIIGGIIIJDGGHGGGJGCEHDGIGIGHHHHFFFFDEEEEEDDDDDCBBDBDDDD@AB8??ACDDDDCCCDDACCB
@3K5
CAAAGCTTTCCCCCTCCTCTGATGATTAAACAGGAACCCAGAGATTTTGCATATGACTCAGAAGTGCCTAGCTGCCACTCCATTTATATGAGGCAAGAAGG
+
CCCFFFFFHHHHHJJJIIJJJGGIJJJJJJIJJJFIIJJJJJIJJJJJIIJJJIJJIJIIEHIJCGIGIJHHHHHHFFFFFEEEEEEADEEDDDDDDDDDB
@3K6
CAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAAC
+
@@CDBFFFHHBFHIIIF@GEB@EBF;BEAFAGGHIDECHICDHGAEBFGI@@@<CGH;;@CDDHEHGHHFCEDFBCCE@ECCCBBAB@@CCCCCCCCCCCC
@3K7
CAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGT
+
BC@DFFFFHHHHGJIJJJIJJJIIIJJJJIJIJJIJJIIIJJJJJJJJIJJIIJJJHFHHHFFCCECCBCCDDDCDDDDCDDCDEDDCDDDDDCDDCCDDD
@3K8
AGGACCCACATACCAACGGCGAGGATCACTTCAGCTCTGGCAGTTTTTGGTAGCTCTTCTGGATGACCCTTCAAATTCTCATTTTATTGCCTGGACTGGTC
+
CCCFFFFFHFHHHJJJJJIJIJJJJIJJJJJJJIJIIIJJJIIEHIHHHFDFFDEEEEEEDDCCDDDDDDDDCDDDCDDDCDEEEDDD@CCDDDBDDBBCC
@3K9
CACATCTGAAGACCAAAGTTCATCACCCCGACAATCCGCAGCAGGTTGGAGTTTGGGTGGTGGATGAACCCCTATAAATTATCATGGTACTGATGGAGGGG
+
(8(((.:@@)>.))<(().)).)))):((((((():.;((<=??1=))')).):)(-7='=9(,(:3927/2(,,:(5((8+((++((+4(8(+3:<7<3&
@3KA
GTGGATGCACCATGCCAGACCGTGGAAGATTTAACGAATGGGGTTGTGATGGCCCAGGTTCTTCAAAAGATAGATCCTGCATATTTTGATGAAAATTGGCT
+
==7AAAA3+<AABB;=7+++@=A?8=BBA*7?AB4:;;;9*)=<66';4.=)372=A5A)>;?@>>?>3<>>;;;5;=?;9>39>??==???=38:88;;?
@3KB
GGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGC
+
@@CFFFFFHHGHGIHIJGIJJJJIJJII@FHGIJIIJHIJGJGIJGGEIGEFGIGGIIIJGH=HCDFFFEACCCDDDDDDDDDDDDDDCCCDDCDDDDDDA
@3KC
GGAAAAAGAAATAGAAATACTTATAGAGGAAAATGAGGACCTCAAACAACAATGAATTCAGCTAAATGAAGAGATTGAAAAGCAAAGGAACACTTTTTCAT
+
?=:BDDDDHHFBH4CFHGGAEHA4C:AA3FFFDHDGCACFG9BG?FD@??88D8)8B<:=CE4=@GH4@@)7()=7=;@D@7(;@A9>?(((,>A>CCCCD
@3KD
TTGAAGCAGAGAATAGCATTCTTAAAGATGAAAAGAAAACCCTTGAAGACATGTTGAAAATACATACTCCTGTTAGCCAAGAAGAAAGATTGATTTTCTT
+
CCCFFFFFGHHHHIJJJJJJIGHCHGGJJGIIJJJJIIJGGGIIIIJEIGIGGGIEHIIIJGIGIIGHIJJJGDHIHHHH?DFFDEEDEEEDCDCCCDDD
@3KE
GCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTT
+
@<?ADFBDDHHFFBGGHEDCI<EBBBEBEDH>EEG??9CGF@?F<BCH<??FEIH=;A@CE;CE@B?BDA;>A;?;ACAAA<??8;3:??CCCC?ACCCA
@3KF
TGAATACTGCACCCAGGACCCGGATGTAATCAACACCGCTTTGCCGATAGAATATGGTCCACTTGTGGAAGAGGAAGAGAAAGTGCCTGTGAGGCCCAAGG
+
@CCFFDFFHGFHHIJEGGHIIJJGIJIIJJIJJJJJIIIGHJJJJJFEHHGHHFFFFDEDACECE>ABCDDBDDBBDDBDDDC+:CAACDDECBDDDDDB?
@3KG
GAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGT
+
CCCFFFFFHHHHHJJJJIJJJJJJJJJJJJJJJJJJJJJJJIJJJJFHIJJJJJHGHFFFFDDEEDDCDDDDDDDDDDD@CCDEDDDDEDDEDDDDDDDA
@3KH
CGACAAAGAAAAGCTCAGTCGGATGGGCAGAGTCCTTCCAAGAAGCAGAAAAAAAAAGAGAAAAACGTCAAGCAGTAAACATGATGTGTCAGCACACCATG
+
CCCFFFFFHHHHHJJJJJIJJJJIJJJJJJJJIJJJJJIJJJJJJIJIJJJJJJHFDDDDDDDDDDDDDDDDDDDCCDDDDDDDCD@CDDCCCDDDDDDDD
@3KI
TGGTTATTAGCCAGAAGGAGATATTTTAGGACTACGAGCTGAAAAAGACTCTCAAAGGGTGGATCTCTCGGCGACTAGGAGGGGGACTTGGGGGAAAAA
+
+1+772<?,,+27C+2+<77++3@B>?+2+2:AB;):)4:**0*0)77)73=3=A8)8(8;'6=7).))'((,/','(,(85)&0&&+(3+(&&&)+32
@3KJ
CTAATTTTAGAAGAAAAGTGTGCTCTACAGAGACAGCTTGAAGACCTTGTTGAAGAATTGAGCTTTTCAAGGGAACAGATTCAGAGAGCTAGACAGACAAT
+
?@@DD?DDDFHBCAF?C:+<3C?AC,CHHHHHE?FHCFGHDHEHIC@9??BDFHHIIIGAAG=CHDFIGIIGCCGHFHHBC@;?>@CBCCC;>@C;ABB?>
@3KK
GTCCGACTCATCTAGAGATGATGGAAAGTGAGTTGGCTGGGAAGCAGCATGAGATTGAAGAGCTAAACAGAGAGCTGGAAGAAATGAGGGTTACCTATGGG
+
CCCFFFFFHHHHHJJJJHIIHIJJIJJJ@FHIIJGJJJJJJJJJJJJJJJJJJIJJJJJJJJJJIJJHHHHHFFFFFEDECBCCCCCDDD?BDDDDDDDDD
@3KL
AAACAGGAACCCAGAGATTTTGCATATGACTCAGAAGTGCCTAGCTGCCACTCCATTTATATGAGGCAAGAAGGCTTCCTGGCTCATCCCAGCAGAAC
+
@@@FDDFDFFHGHJJJBHHIJIJJJJJEIJIIGJJGC:DGIGGHGAHDIHHHGJJJIJGIEHIEGHGGCGHGEHHGFFDFDECCDEDDDDDDBCDDCC
@3KM
CAGCAAACAAATCAAAGCTCATGATGGCAGTGTGTTCACACTTTGTCAGATGAGAAATGGGATGTTATTAACTGGAGGAGGGAAAGACAGAAAAATAATTC
+
==;AA<@AA;+<AA<<<3A=<CAA3<7@C<?AABBBBBB>AB<BA?<?99A4=A7*9?<A2>A<AAB78AB>BB>AAAA@=@<@=;>>?=:;9=9=>?=>>
@3KN
CTCCAACGAGTACCAGCTGATTGACTGTGCCCAGTACTTCCTGGACAAGATCGACGAGATCAAGCAGGCTGACTATGTGCCGAGCGGTGAGGACCTGCTTC
+
:1:D1:?B7FBDHIIIDG9:C:+<FB+2?@F>3C:C<?BGB4B*?GHFHGDF8?@B'5'5?>A=A@D?/6;26@C>C>;-;8',85&0)((+++(+98:4:
@3KO
GAAATCACTGTGCTAAAGGCGGCTTTGGCTGATGTTTTGAGGCGTCTTGCAATCTCTGAAGATCATGTGGCCTCAGTGAAAAAATCAGTCTCAAGTAAAGG
+
CCCFFFFFGHFHHIJJJIIGIJIJJJJJGGIIGIFHHIGIJJJJJHHHFFFFFCCEDDDEEDDDDDDCCCDDDDDDCDDEDDDDDDDDDDCCDDC@CCDCC
@3KP
CACAACACCATGGTTGGCAGTGCGGCCAGCCAAAGCTTTCCCCCTCCTCTGATGATTAAACAGGAACCCAGAGATTTTGCATATGACTCAGAAGTGCCT
+
C@CFFFFFHHHHGHIJIJJJHJJJJIJJIIJJJJJJJJJJJJJJJJJIJJJHHGHHHHFFFFFDEEEDDDDDDDDDDDDDEEDDEEDDCCCCDDACCCC
@3KQ
TCCATCGCAGTCCATACCAGATAGCAGCTACCCCATGGACCACAGATTTCGCCGCCAGCTTTCTGAACCCTGTAACTCCTTTCCTCCTTTGCCGACGATGC
+
CCCFFFFFHGHHHIJJJJIJJJJIJJJJJJJJJJJJJJJIJJJJIGIJJJIJIIJIHFEFFFFEEEEEDDDDCDEDEDDDDDDDDDDDDDDCDDDDBDDBD
@3KR
CTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCT
+
C@@FFFFFHHGHGIIJJJJJJIIJIJJJJJIIJBGFHGJJJJHHHIIJJJGIJIIIJJGIIJHHGFFFFEEDDDDDDDCCDDDDDDDDDDDDBCDCCDDDD
@3KS
CTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTTATGGGC
+
CC@FFBDFHHGHHJJFGIEFHIHIJIJGIJJJJJGIIJIJJJGJGIJIJFIIJID=ACGCCGHGGHHFDDDC?BDBDDDBBACDDCEDDD395?CCACDD?
@3KT
CCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGT
+
@@@DDDDDHHHF<EFB3AF>CACFHEBFIIEDFGGC=BGIIGC=@FA@@CCCA3==?CDEEE;?@@CCAACBB;;@C>CB?<868:ACBBBCCA>ACB8?4
@3KU
GTCTGAGCCAAACATCCCCTTCCCACCACAAGGCTTTAAGCAGGAGTACCACGACCCAGTGTATGAACACAACACCATGGTTGGCAGTGCGGCCAGCCAA
+
@?@DDDBDFHAFHIGIIIIGGIIIIIIIIIIIGGGGHIIEHIIGII9BBFBHG<@EBHH=AEEB?@C>CEA=A;@@@CCACCB@CC?3:>>B>@BBBBAC
@3KV
CTGAAAGTATTTTGGTCTTCTGGAGACACGGGACAAGGCTTGCAGCCAATTTACTGGAGCAGGGATGACGTAGCCCAGTGGCTCAAGTGGGCTGAAAATG
+
CCCFFFDAFFFHFGIGIGGGIIIIGGGEGHIIGGJIJGIFGIGJJJIIIIJJJHHHG@GEHHHH=DFFEDACDDDDDDC@CB<@CCCACCDBCB<CCCAC
@3KW
CTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGC
+
@C@F=DFDHDFFBGHE>ABEEHEHAGHGCGIGHIIIIGIIIGHIIIGCFHIGIEEGICFHCEDGGE?EHC>B3?;>A>@3>3@AAB@=9A@CC@?CB>CA
@3KX
CCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCAC
+
CCCDDFDFFHFHHJIGJIJGIIIIJJJIJJIJHGGIHIJIJGEGIGGE@FHHGGIJHHFFBEFEEACE>?CDDDDDCCDDDDDDDDDDDDDDDCCCDDDDB
@3KY
AGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAA
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJIIIJJJJJJJJJJJJHHHHFFFFEEEEEDDDDDDEDDDDDDDDDDDDDDDDDDEDDDDDDDD
@3KZ
TGAAAGCCTTACAGAAATCTCCAGGACCTCAGCGAGAAAGGAAGTCATCTTCATCCTCAGAAGACAGGAATCGAATGAAAACACTTGGTAGACGGGACTCG
+
@@<DDD>DA<<A?FH@H<CHCC<CFEHEGE>FGHI8D<BGG?G9?BDEFHIIIIDD3=@=@F@;CC;?6??BDE>B3;AC>@BB@@A>,,55:?B@<B8?<
@3L0
ACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGG
+
1+:B;A:=C:AAB>AEEC3<;B:<<CD>A>@EBE9DDEDBDBDDDDDED<?DDD:3BDE<B;2@7ADD<?;CC7>@D>>@>>A;;A;(,>>A???>9;5;
@3L1
CATGAACCACATCATGGTCTCTGTCTCCCCGCCTGAAGAGCACGCCATGCCCATTGGGAGAATAGCAGATGTGCAGCACATTAAGAGGAGAGACATCGTGC
+
C@@DDDFFFHHHFHHGIIIIJGIGHIIJJJGGIGGIJJIIJJJGIIGIJJJJJJJJJJJHHGEEFFFFCEECCCCDDDB?CCDCCCCDA@??DDCDCDBBD
@3L2
TGAATGGCAAAGCTCTCCTGCTGCTGACCAAAGAGGACTTTCGCTATCGATCTCCTCATTCAGGTGATGTGCTCTATGAACTCCTTCAGCATATTCTGA
+
CCCDFFFFHHHHHJJJGJIGGIIJJIJIJJJJJJIJJGJJJIJJJIJJJJJJJJJJJJIJJEIJCGHHFEHHFFFFFFFEEEECEEDDDDCDCCEFEED
@3L3
GATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGC
+
CCCFFFFFHHHHHJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJGHJJJJJJJJJJHHFFFFDDDEDDDDDDDDDDDEDDDDDDDDDDDDDDDDDDEDDD
@3L4
CTTAAAGATGAAAAGAAAACCCTTGAAGACATGTTGAAAATACATACTCCTGTTAGCCAAGAAGAAAGATTGATTTTCTTAGACTCCATTAAGTCCAAATC
+
C@CFFFFFHHHHHJJJJIJJJJJJJIJIJJIJJIIHGIJJJJJJIJIJJJJJIIJJJJIIIIJIJIIJIIIJIHHHHHHHFFFFFFEEEEEEEEEDDDDDD
@3L5
TTGCCTTCTCAAAGTAAAAGATGATTTAGAAGACAGTAAAAATAAACAGGAATTAGAGTATAAAAGTAAACTTAAAGCACTTAATGAAGAGCTTCATTTGC
+
CCCFFFFFHHHHHJFHJJJJHHGGIIJIIJJJGIIJIIJGIJJJJJIJJJGIJJJJHJIIJIJJJIGIIJJIGIJJIIJGHHHHHHFFFFDFEEEDDEEEA
@3L6
GGGAGACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTT
+
BCCDFADFHHHHHGIGGIJIIJIEHGAFHFCHIIIHIGGIGFIIIHBHFFFDDDDDCDDCDEDDDDDCCCDDDDDCCCCDDBBDDDDDDDDDDDDD@CCDD
@3L7
ATAAGTTCCTCAGGGCCCATGGGCCAGATGCAATGATCCTTGTGGATGGACAGCCACGCCAGGCCAAGGGTGAGCTGGGGCTCTCCCAAATGCTCCACATT
+
<@@FFFFFHHFGHHGIHEGHGHIEGGGIIIIJIJIJJIIIBFHHD>FHFEGGCHHEGGBCHHFDEDFFFD6=BDCCDDBDDBDCDCCCCD>ACACD@?CCD
@3L8
CAAACAAGAGCCAGGAATGTATCGGGAAGGACCCACATACCAACGGCGAGGATCACTTCAGCTCTGGCAGTTTTTGGTAGCTCTTCTGGATGACCCTTCA
+
CCCFFFFFHGHHHJIIJJIHHFHIIIFHJIIJJIIIJIIJJGGIIIIIBEDCDDDCCDDCCCDDDDDDCD<CDDDDD8>@CCDDDDCCDC@CDDDDCDDD
@3L9
CCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCAT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJIJJJIIJJJJJJJJJJJJJJJIJJJJJJJJJIHHFFFFDEEEEEFEEDDDDDDDDDDDDDDDDCDDDDE
@3LA
CTACAAGCGAACCCCTTAATAAGAGCAACTAATGTCTCTTCGGGGGGGCTCTGGGGCTGGTTCAAGGACAACGAACTATGAAGGAAAGGCTGGATCCTTGG
+
;(759))2(-(:((3(<1))2:)).)).())).))00).0)9(-'95&5&+2++()&&)0((+(+((+2(((0(+&(((+(((++(+(((+(&(((++(4+
@3LB
AAACAAGAGCCAGGAATGTATCGGGAAGGACCCACATACCAACGGCGAGGATCACTTCAGCTCTGGCAGTTTTTGGTAGCTCTTCTGGATGACCCTTCAA
+
?@@?DABDDHDHFFHIIGAFDAEFGCHGGHHICHEIIICEHGGHEHGFBCCC??CCCACCC>CC<3@C?<@CA?BBBCC>CCCC3:AC:@@>>C@CC<CC
@3LC
CAAGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGC
+
==+<+<?7A>@7+77+<AA+3<?7;<?*?5=*11?AA3=<A>>23*9(==BAA8==>>;A>>2>AA;AA;AAA3>>@@@;3',/;>5(,:=3;>;88??
@3LD
CACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGT
+
CCCFFFFEFHGHDGGIIGGEGEHGIGGIJJGIIJIJJIGGIIIGDCHGGFHIJJGIIJJHHGHGFFD8=BCDDDBDADDDDDBBDDDCCCDDDDDDDDDD3
@3LE
GGGGAATCTACCCCAACCCCAACGTCCCCCGCCATCCTAACACCCACGTGCCTTCACACTTAGGCAGCTACTACTAGAAGCTTACTCATCAGTGGCCTTCT
+
@@@D78B;FDHFD;DE=FAGB@FE?FC@CG>GADBFEGGGGGEHGCCHC?EE>ACCCCCCC>;ACC??CCCC>::5:4>A>@CC@A@ACCA>>AABBCC@@
@3LF
CCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJIJJJIJJJJJJJJJJJBGIJJJJJJGIJIIJJJHHHHHHFFFFEDCEEDDEDDDCDDDDDDDDDDDDDDDDD
@3LG
CAAGATAAAAAAAGTAGAAAACTCAAATAAAGAAGAAATACAGGAAAAGGAGACAAACATTGAAGAATTAAACACAAAAATAATAGAAGGAGAAAAGAAA
+
@@@DDFFEFGHHGJ<CFGHGIGIGDHGHI@GGDGEGHIIGGHHIIIJJJIHGIJGI)66CE?HEHGFFFFFFCCCCDDDDDDDEDA@AC@<<<ADDDDDD
@3LH
CAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGT
+
@@?DFDBDHHHHGIEGIIIIJJGIIJIIGGCCHGHJIGFEGGIJJJDHIGGGIICGHHGGHFF=ACCCDDDDCD><ACCDDDDDCDDCDDDDDDCCCDDDD
@3LI
TGTAGGAAGTGGCCTGTGTAGTGCTTCAAGGGCCAGGCTGCCAGGCCATGTTGCAGCTGACCACCCACCTGCAGTGTACCGCCGGAAGCACCAGGAGCTGC
+
CCCFDDFDHCFHHIIE<BEEHABHIGGGGBGIGFGC?FIGEGGHEGGGIIIIGIGI@GIIIIIIIEHHFDFDFE3>>@CC8??=@>B>BCCBBBBBBBBCA
@3LJ
ACTCAGCAAGGTACAACTATTCTTCAGTATGCACAGACCTCTGATGGACAGCAGATACTTGTGCCCAGCAATCAGGTGGTCGTACAAACTGCATCAGG
+
CCCFFFFFHGHFHIJIJJJJJJJJJJJIIIJJJJJIJJJIJIJJJJJJJIJJJJJJJJJJJJJJJJIIIJJJJJJHAEHBDFDEDDDDDDDDDDDDDD
@3LK
ACTTAGAGCAACTCAACCAAGTGAAAATGATAAACTTCAGAAAGAACTCAATGTACTTAAATCAGAACAGAATGATTTAAGGCTACAGATGGAAGCCCAAC
+
CCCADFFDDDDHHDGGBHGGGFHHGHGEEGIIIIIJDGHHEGGGHJICEGGGHICGGDGFHHGIIGHGGGCH>DHGIEHHHHFEECDFFEDCCEEBDDBDD
@3LL
ATTAACTGGAGGAGGGAAAGACAGAAAAATAATTCTGTGGGATCATGATCTGAATCCTGAAAGAGAAATAGAGGTTCCTGATCAGTATGGCACAATCAG
+
CCCFFFFFHFHHHJJGGHIIJJJIJJJJJJJJJJJIJIJJJJJJJJJIJJJIJJJJJJJIIGI<GIHHEHEFFFDBEECDEEEEDDEEEDDDCDDDDDD
@3LM
AAGAATTCCAACCCCGACGAGATTGAAATCGACTTTGAGACCCTGAAGCCGTCCACACTGCGTGAGCTGGAGCGCTATGTCACCTCCTGTTTGCGGAAGA
+
CC@FFFFFFFHHHIIJJJJFIGIHIJJIIIIGIGGGHGIIIJJJJJJIEIHHFFFFDDCCCDBB@DDCCDABDDDDDDDDDDDDCDBCCACDDDDDD@DD
@3LN
CCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGAC
+
CCCFFFFFHHHHHJJJIJJJJJJJJJJJJIJJJJJIIJJJJJIJIJJJJJJJIJJJJJJJJJJJJJJHHHHHFFFFCEEEDDDDDDDDDDDDACDDDDD
@3LO
GGGACGCGCGTGGCAGGCAGTCGCTCTGTGCGGCCGGGAGGGGGCGGTACGCACGGTCCGCGCATCCCTACACCCCCCCGCCGGTGCGGGGGCCGGAAGGT
+
0(((-((((00(56)0=(0())7'-6(;.:34'--''''','&&&)&&&&&&2&&&+2&)&)&&))((((+(+(5&&0&0&&&&)&&)&&)&&&)))00((
@3LP
AGAAAGCAAGAATGCTACTCCCACCAAAAGCATAAAACGACCATCACCAGCTGAAAAGGCACATAATTCTTGGGAAAATTCAGATGATAGCCGTAATAAAT
+
@@@DDDADDD2A<CFHBGIGFHIGHHB=FGEHCDGGEB?<GBGDGGACF@F@>CDHG@(=AE>E=BEDE>@;>A;ABCCC>>5;@A>;@@CCB8@@B>:CC
@3LQ
ATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCC
+
CCCFFFFFHHHHHJJJJJJIJIJIJHIIJIHIIJJJIJJJJJIJJIJIJAHHIJHGHHFFFFDDEDDDDDDDDDDDDDDDDDACDDEDCDDEDDEDDDD
@3LR
ATAATTTTTATGGTGGGACGAGGATACCTGTCTCCAGATCTCAGTAAGGTACGGAGTAACTGTCCAAAAGCCATGAAGAGATTAATGGCAGAGTGCCTCA
+
@CCDDFFFHGHHHCDGIIGFHIIGIJJJIJGGIJJJJJIEBHIGIJJJE=FHHIDHCEHHHHEHFFFFFDEEEEECCDCDDDDDDDDCBCDBB:@ACCDD
@3LS
GTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTAC
+
CCCFFFFFHGHHHJJJJJJJJJIJJJJJIJJJJIGHIIJJJJIJIJIIJJJJJJFHIJIJIJGGIJHHHHHFFFFEEEDEDCDDDDDDDDDDDDDDDDDDD
@3LT
CTGGGCCGCGTGGTGCACATCATCCAGTCACGGGAGCCCTCCCTGAAGAATTCCAACCCCGACGAGATTGAAATCGACTTTGAGACCCTGAAGCCGTCCAC
+
CCCFFFFFHHHHHGHIIJJIJJJJJJJJJJIJIJIJJJJJJJHHHHHFFFFFFEEEEDDDDDDD@B@BCDDDDDDDDDDDDDDDDDDDDDDDCDDDDDDDD
@3LU
CCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGAC
+
@CCDDDDFDFHFHEIIFIGFHIGIIHIIIIBHHIIIEFGIIIGGIIIGIIFHIIIIIIIIIIEHGEHHGHCEFBDDCEDDDD?BBBBCDCCDEDD@CCB>
@3LV
CAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATAT
+
@@@BDDDD+AF?<EEEBEFCHGGEH@E?;FF>FBF??CGHIII@F9?FBF@DG=CCCFHGHIIIFFH;@DE>;@A;;>CAC?BC?BCCCCCC:CCCCDC
@3LW
GCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGC
+
CCCFFFFFHGGHGJIJIIJJJJJIIIJJJEIIJIGHJJJJFIJIJJJIIIJJJIIIJJIJJHIDHHHFHHFFFFEDCDEDDDDDDDDDCCDDDDDDDCDB
@3LX
CTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCT
+
?@@D;=BD8D<DC8C@<?GG?@C7FG?90:??@:D6?===27@FF<).77@CE==)=>?)71??B36>A3>>B@BAA:?7<9?@@@BBB3<89A:@BB4:9
@3LY
TACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTT
+
CCCFFFFFHHHHHJIJHHIJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJIJJJJJJIJJJJJJJJIHHHHHFFFFEEEEEEEDDDDDDDDDDDDDDDDDE
@3LZ
TAATGGCAGAGTGCCTCAAAAAGAAAAGAGATGAGAGACCACTCTTTCCCCAAATTCTCGCCTCTATTGAGCTGCTGGCCCGCTCATTGCCAAAAATTCAC
+
=@@1::DBDFF:AGF@GBFHEF:12CGD?@BC<B9:3BFFEFGFEGEFF<BFFFBFFGI<CEEFFF:AC7?;;@>ACA@BB@:8?8:>A>:@>@8<@B(>A
@3M0
GGGAAGCAGCTCGAGAGTGTCGTAGAAAGAAGAAAGAATATGTGAAATGTTTAGAAAACAGAGTGGCAGTGCTTGAAAATCAAAACAAGACATTGATTG
+
@@@DDDDDHFFHF@EEGFHHEG<EFEEGIGHGFGGGGIIGIIHIIEHIFBCGHIGIIIHGGGH@DHFHHHD3;B;>CCC>>@@CC;??999>>A>3;@A
@3M1
GCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGC
+
@@@FDDF?AHHHHIIEIIIIBGIGII?>GCHEHGIIIICFAGG=GIIIIIGEHIIIIIII;EEGHHCFHHHFB@BBDCEE@CDBCDDDDDBCBA?BDDB
@3M2
AAACAGAAACATGGTGAGATTAGTTTTCTAAATGAAGAAGTTAAATCTTTAAAGCAAGAGAAAGAACAAGTTTCATTGAGATGTAGAGAGCTAGAAATCAT
+
???;DA+=ADABD32A+A3AFEDEEECFA>C<BBC?:?EB**9CDEEIIIEEDD<DCDA@B@.BC(=CDDAC;===CE)7(=;ACDDDD?@AAAAA>AA>A
@3M3
GGAAAGTTCACTGCTGGCCTATAATACAACCTCTCACACCGACCAATCCTCACGATTGAGTGTCAAAGAAGACCCTTCTTATGACTCAGTCAGAAGAGG
+
@@@FFFFFHBADDHGGJBHGGGGGEHGJGAHHEHGGIGEHEIBHEHIEFBG@FGGHIA@EAECEAEEFEFDEEEDEDDDDCACCCDCDDC:@@ACA9AB
@3M4
CCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGCTCATTCCGACAGGACCACCCCAGTAGCATG
+
<<<8@<:<<<1>?7=1)))3(:6131<=<..)1991=>33.<>5?33>1)6)9.(<>1:/'';;===?0()..:3;89;<</25,2;/2:8:(++(/::(2
@3M5
CTTAAAACAGAATTGTTAGAAAAACAGATGAAGGAAAAAGAGAATGATCTTCAAGAAAAATTTGCACAACTTGAAGCAGAGAATAGCATTCTTAAAGATG
+
CCCFFFFFHHHHHJJIJJJJIJJJJJJGIHHHIIIJJJJJJJJJJJJJJJJJJJIJJJIHIJJJIJJJJJJHHHHHHFFFFDDEEEEDEDDEEDEDDDDD
@3M6
AAAAACATCACCCTCATTCGGGGTCTGGGCCATGGCGCCTTTGGGGAGGTGTATGAAGGCCAGGTGTCCGGAATGCCCAACGACCCAAGCCCCCTGCAAGT
+
CCCFFFFFHHHGHJJIJJJFGGIIIIGIJIJJJFGGIJJIJJJIIGDHF;ADFFFFFFEDDDDDCCDDDDDBBBDDDDDDDDDDDDDDDDDDDDDDDDDD@
@3M7
CCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTTATGGG
+
@@@DDF>;FFDFDGGGIIIDHIIIGIIIGCHIIGIHIDGFCHGGH?DBHIIEI1=CEH=CHECE>EHB4=>C(;??A?@=BB5@C@CDCBB39@BCACCCB
@3M8
TACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAG
+
CCCFFDEFHGHHHGEB?EFHGGIFFGIIGHGIIGGIGGCEFHIFHHJIJIIEHIJJHCHIJIJJIJGHHHHFFEBCCEEEDACCCCD?C?AB@DDD<C
@3M9
TGTCAACATACTAGATGTTAAAGATGACTGTGGCCTCCAACTAAGGGTAAGCGAGGACACCTGCCCACTGAATGTTCATTCTTATGACCCCCAAGGAGA
+
CCCFFFFFHHGHHJIIJEHJJIIJIIJJGGHFAFHJIIJJJJJJJJIF09?FHIGGFIIJIGIIHGHHDFFFFFEEEAECCECDCDDDDDDDDDDDBDD
@3MA
CGATGCCAAGGGAAGGACGTCCTATGTACCAACGCCAGATGTCTGAGCAAAACATCCCCTTCCCACCACAAGGCTTTAAGCAGGAGTACCACGACCCAGTG
+
CCCFFFFFHGHHHJJJJJJJJJJJJJIIJJJJJJJJJJJJIIJJJJJJ/8CGIJJJJHHHHFFFFFDDDDDDDDDDDDDDDDDDDDCDDDDDDDDDDDDCD
@3MB
GTAACTGTCCAAAAGCCATGAAGAGATTAATGGCAGAGTGCCTCAAAAAGAAAAGAGATGAGAGACCACTCTTTCCCCAAATTCTCGCCTCTATTGAGCTG
+
C@BFFFFFHHHHHJJJJJJJJJJJJJIJJJJJJJJJJJFHIJIJJJJJFJJJJJIIIIIJIJIIIJJJHHHHHHFFFFFDEEEEEDBDDBDDDDEDDDDDD
@3MC
CCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGAC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJIJJJJJJHHHHHFFFFFEEEDDDCDDDDDDDDEDEEEEEDDD
@3MD
TGAGCCAAACATCCCCTTCCCACCACAAGGCTTTAAGCAGGAGTACCACGACCCAGTGTATGAACACAACACCATGGTTGGCAGTGCGGCCAGCCAAAGCT
+
C@CFFFFFHHHHHJIJIGIIJGIJJJJIJIJIJIIJJJIJJJJ;DHHIJJJJJJJJCE=CHFHGFCFFDDBDDDDDCDDDDDDDAACBBDDDDDDDDDDDD
@3ME
CACTCTCTTATTCCCTAGATTTCGCCGCCAGCTTTCTGAACCCTGTAACTCCTTTCCTCCTTTGCCGACGATGCCAAGGGAAGGACGTCCTATGTACCAAC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHHHFFDDDDDDDDDDDDDDDDDDDDDDDDDDEEDDDD
@3MF
CCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTTATGGG
+
===A<7<=A82<;?=@9?++<3,<7@BBBCBBA<>?1?:35A?5A*9=4AAA6<BAABAA)==>;==<@<3=22;;;;=:==5;;883:;2+&&+3838?9
@3MG
ATTTCGCCGCCAGCTTTCTGAACCCTGTAACTCCTTTCCTCCTTTGCCGACAATGCCAAGGGAAGGACGTCCTATGTACCAACGCCAGATGTCTGAGCCA
+
?@@DDDAD@CDD@?EBBE@G?EBEGGDDEDGHABDBG?DE>;DFCC9CH<G'-==7A@7?BA=ABB=??,8?BC@A5;>ACCB8>BB>?CC>A@C@CA>3
@3MH
GTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACC
+
BB@FFFFFHHHHHJJJJJJJJJJJJJJJJIJJJJJJIIJJJJJJJJJJJJJIJJJJHIJJJJJJJHHHHGFFFFFFFEEEEEEDDDCDDDDDDDDDDDDDD
@3MI
GCCGGACAAAAGGCCGGTGATTGCGGAAATCAGCAAAGACCTGGAGAAGATGATGGTTAAGAGGAGAGATTACTTGGACCTTGCGGCGTCCACTCCATCTG
+
;8;(5>?@@?179>3(<8/())<39(7((0;;)336=)).=130=>???9?83=8).:3(69(;((3(,(,:((7<0(((36(3&&50)568;62+8/:5(
@3MJ
GGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACAC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJIIJJJJJJHIJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJHHHHHFFFFFDDEEDDDDDDDDDEEDDDDDDD
@3MK
GTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGCACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGC
+
CCCFFFFFHHFHHJJEGIJJIIJIJGIIJIJIJJIJJJJJJJJJJJIJJJJ>AHEEEEBDFFFFDEEEEEEDDDDDDDAADDDDDDDDBBDDDDDDDDD
@3ML
ACCAGGAGCTGCAAGCCATGCAGATGGAGCTGCAGAGCCCTGAGTACAAGCTGAGCAAGCTCCGCACCTCGACCATCATGACCGACTACAACCCCAACTAC
+
CCCFFFFFHHHHHJJJJJJJJJIJJJJJJJJIJJJJJJJJJJJJHIJJJJJJJJJJJJIJIJJJHHFFFFDDDDDDDDDDDDDDDDDDDDD>@DDDDDDDD
@3MM
ATTAGTTTCTTGCAAGAGAAAATTAAAGTATATGAAATGGAACAAGATAAAAAAGTAGAAAACTCAAATAAAGAAGAAATACAGGAAAAGGAGACAATCAT
+
CCCFFDFFHHHHHJJJJJJJIJJJJJJJFHIJJJJJJJJJJJIJJJJJJJJJJJJGIJJJJJJJJJJJJJJJJHHHHHFFFFFFEEEEEDDDDDDDDDDDD
@3MN
CTTCAACACCCAAATTAATACCAAAAGTTACCAAAACTGCAGACAAGCATAAAGATGTCATCATCAACCAAGAAGGAGAATATATTAAAATGTTTATGCGC
+
CCCDDFDDFHGHHGIIJIIGIGHIIIIFGIIJJJJJJJIIGGEGHIGIEGIIIHFHIFHIIEHJIJJIJIJHEGHFFFDEEEEDFFEEDDDD@DEDCCDDD
@3MO
CCTATGTTGACCTTGATCGTCAGCTGAAGAAAACTACAGAGGAACTAAATGAAGCTTTGTCAGCAAAGGAAGAAATTGCTCAAAGATGCCATGAACTGGAT
+
7@?BDBDD?A<DD<4A+<AF?;E@92+93A?CF>?9?FG?@D9B;D?DFFCF@F:BFC<84=B@=FEF@@=;>EF7);B3;7;@A33.(;>A@AAB;@A3(
@3MP
CTTGTTGAAGAATTGAGCTTTTCAAGGGAACAGATTCAGAGAGCTAGACAGACAATAGCTGAACAAGAAAGTAAACTTAATGAAGCACATAAGTCCCTT
+
?;=B=B;A,?4ADAE4AEFCCF4EBE?2C@?EDAEEFB9?DDIDDEB<D??BDDIA<B>8=BCEACCCDA@.=?CD>=A@>ADD@AAAA:>>A(->>>>
@3MQ
CTCCCCAGCCCTCTTCACAACCTCTCCAAATACACAGACAAACTCCAGAAAGCAAGAATGCTACTCCCACCAAAAGCATAAAACGACCATCACCAGCTGA
+
CCCFFFFFHHHHHJJIJJJJIJJIIIJJJGHIJJJIJIJIIIIEGIIJJIIIJIJIJJJJGGIJGIIGEHHEFFFEEEDEDDDDBBDDDDDCDDDDDDDD
@3MR
CCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGT
+
CCCFFDFFHHHHHJIJIIJJAHIJJIIJJIJJJJJJIJJIJJJJJJJJJIIIHHHGHHFFFFFFCEDEEDDDD;ACDDDDD?@@DDDDDDDDDDDDDDDDC
@3MS
CTCGTAACACAACTAACAAAATTTGACATCACCTACTCCCTGAATCTCCCACCCATCGGAACTAAAATTACCAACTTTAGCCAACTCTTCGAATCACTACC
+
(;<(2-@(6)@1-:?@).48(36))2;4)))).):;)9=>))))0))0))0(<'7))(-;(')).8)<))8)3),(.(..6(-,((,(,(((,((,(((+(
@3MT
TGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACC
+
CC@FFFFFHGHHHJJJJJJJJJJIJJJJJJJJJEGHJJJIIJIJJJJJIJIJHHHHHHFFFFFDEEACEDDDDDDDDDDDDDDDDDCCDDDDDDDDDDDDD
@3MU
AGCCAAGCTTGCCCAGTTTCGACAAAGAAAAGCTCAGTCGGATGGGCAGAGTCCTTCCAAGAAGCAGAAAAAAAAGAGAAAAACGTC
+
CCCFFFFFHHHGHJJJHIJIJJJJJJJJJJJJIJJJJJJIJHIHIJJJIJJGIJJJJJHHHEHFFFFFEEEEDDDBDDDDDDDDDDD
@3MV
AGAGGACAAGTGCAAGCCTATGTCCTATGAGGAGAAGCGGCAGCTCAGCTTGGACATCAACAAGCTCCCCGGCGAGAAGCTGGGCCGCGTGGTGCACATC
+
@@?DBEDFGD?C?FEFGHDDHHIGGEGHGFGABGGGEIIBHGGGFDFGHGIG?ADCGAAEEHHCFFCECCBB??D>99CCCCCBBBB<B<@BB@CDDDCD
@3MW
CATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCT
+
@@??;B+AAF?CA?F<?FEDGDGGIHEB@HA???DDGH>FAG?BF@HBGC@?FA>CABB8;@@4-=?EC?CE@DE@CC;A>-5>;@C55:>@C<CA?C9?A
@3MX
GCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCC
+
?<<ADDDBFBFFFBF<CF4:AFD@FBGAF3?DFE>FFIGC@GFIFIIEIIIFII7CFGDEDCEII;A?ACBDDDD;>@;ABBB?=@BB?1<@?3>>BDBB>
@3MY
CTGTGAGCAAGATGCGCATGGCCACCCCGCTGCTGATGCAGGCGCTGCCCATGGGAGCCCTGCCCCAGGGGCCCATGCAGAATGCCACCAAGTGTGGCAAC
+
CCCFFFFFHHHHHJJIJIIJJJJJJJJJJJJJJIIJJJJJIJIJJJJHHHHFFFFEDDDDDDDDDDDDDDDDDDBDDDDDDDDDDDDDDDDDCDDDDDDDB
@3MZ
CGCCCATGAAGAGCAAGCCCCCTCCCACGTATGAGTCGGAGGAAGAGGACAAGTGCAAGCCTATGTCCTATGAGGAGAAGCGGCAGCTCAGCTTGGACATC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJHIJJJJJJJJJJJJJJJJJJIHHHHHHFFFFFEEEEEFEDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDD
@3N0
GGGAGGGTTCTGATGCACTGCGGTGAATTTTTGGCAATGAGCGGGCCAGCAGCTCAATAGAGGCGAGAATTTGGGGAAAGAGTGGTCTCTCATCTCTTTTC
+
?@<;DDDACFDDDGIGIIIBEGEFDHIIIIFHBGIEGIEGIIIDIIHFFDEFEEECACDCCDBDD?B@BCDD>CBD79?A?C>AB@@C@ACCDDCDCCCDC
@3N1
CACTTTTTCATTTGCTGAAAAAAAACTTTGAATTTAACTATCAAGAGTTACAAGAGAAGTATGCTTGCCTTCTCAAAGAAAAAGATGATTTAGAAAACAGT
+
>77<<AA8C,<CC<,<+27A<=CAAAB=:0?=*000?*00*9*09A5=8=A>7)).).)....).=.(=;3.77.(..(6>5(,((5(,,,;;9>(,,23:
@3N2
GTGATGACATCTCCTGTGACTCTCACCTCTCAGACAACTAAGACAGATGACCCCCAATTGAAAAGAGAAATAAGGTTAATGAAAAACAGAGAAGCTGCTCG
+
?1:DDADDB?FDFFIFAFFHIEFI<EGI@CGIC<?;CFFGBGBGFBBGFF@F>DFFFDEEGIIGF;;DEFFCA>C7;?B;?CCACABB=>ABB@A>@ABB?
@3N3
CTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGC
+
CCCFFFDFHHHHHJJJJJJJJJJJJJJJJJIJIJJJJIJJJJJJJJJJJJJJJJJJJJJJJJHHHHHHFFFFEDDDEDDDDDDEDEEDEDDDDDDDDDDD
@3N4
CAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCG
+
;((:;=?1>438)<@?)8@>)(<5888639=)3=9916.0:39;<79>:61)<69836:=888>??55>3)9;=0365=39;3;/2'((2(+86((28+62
@3N5
CCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATT
+
@@<?DDDEBHHFADBGBFCHGECCG?EBBBHIGAHHII?DDDFEGI)8@GAFHGGICHHGIGG=D==@7??EEHE>BDECAAC>CBBAB?<CC@CCB>:@@
@3N6
AGGAAGAGAAAGTGCCTGTGAGGCCCAAGGACCCTGAGGGGGTTCCTCCTCTCCTGGTCTCTCAACAGGCAAAACGGGAGGAGGAGCGCAGCCCAGCTGCC
+
@CCFFFFFHHHHHJJJGJHIJJJJJJJJIIJJJJJJJIJJJJAGHIIJHHHGGFFFFCDEEDEEEDDDBDDBDDDDDDBDDDDBDBADDBBDDDBDDDDDD
@3N7
CGTCAGAGTGTGGGATTCTGTTACTCTATCCACACTGCAGATTATTGGACTTGGCACTTTTGAGCGTGGAGTAGGATGCCTGGATTTTTCAAAAGCAGATT
+
BCBFFFFFDFFHHJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJIJIJIJJJJJIIIIJJBHHEHHFFFFFFEEEEDDDDDDDDDDDDDDDDDDD
@3N8
CCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGGCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTCCTCCCCTTGGAGGGGCACAAACG
+
1:;A+00<DD?AAE322<CCF<+<CBEBEC31:1:9)0?D?0BD<9DEIADI;@=@8@66@==7-=/5>'55255>A>;(,,8??=93(29?5><>8>(9
@3N9
CGGCTCCTCCAAGATGAAGGGCTTCTCGTCCTCAGAGTCGGAGAGCTCCAGTGAGTCCAGCTCCTCTGACAGCGAAGACTCCGAAACAGGTCCTGCCTAAT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJDHIJJJIIIJJJJJGHIGHIIJHHHHHFFFFFEEEDDDDDDDDDDDDDDDDDDACDDDDDDDDD
@3NA
TTACAAGCCTTCAAAAATGAAGTAGGAGTACTCAGGAAAACACGACATGTGAATATCCTACTCTTCATGGGCTATTCCACAAAGCCACAACTGGCTATTGT
+
CCCFFFDDHFHHFHJJJJIFGIFHGHIJGHGHIGGIIIGIIIJIGIIEEBFHIGGJIJJJIIJGGHGEHGHFFHEDFDFFEDBCCDDDBDBCDDDDCDDDD
@3NB
CTACGGGCAGCAGAGTCCTCCCCTTGGAGGGGCACAAACGATCAGTAAGAATACAGAGCAACGGCCGCAGCAAGATCCGAATCAGATCCTGGGCCCGACC
+
:?:4=)1<8)++2:CA4A+222C3?)C*?BF8:((0.=(;@=(@=)>.).?C=7?7@???>(93'2',)))(++9((+2(+8(((4>>:(490(<>@0).
@3NC
CTCAACCAAGTGAAAATGATAAACTTCAGAAAGAACTCAATGTACTTAAATCAGAACAGAATGATTTAAGGCTACAGATGGAAGCCCAACGCATTTGCCTC
+
@@@DDDFFDHFHFIGIGJIIIEIJIGG>HHGIFGHIIJJJJGFIIJJEDHIHIIBHIIJGGIGIJJIJJGIJGJGGHIGHHHHHFFFFBDDDDDDCDCDDD
@3ND
CTCGGATTCTTTTTTCACCATTCTTCCACCCTGGAAACTCTATACACACACAGCCGGAGGTCATACTGCATCAGAACCATGAAGAAGATAACTGTGTCC
+
CCCFFFDFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJIJJIJJJJJJJJJIJJJJHHFDCEEEEEEDDDDDDDDDDDDDDDDDDCDDDDCDDDDDDD
@3NE
TGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGG
+
CCCFFFFFGHGHGIJJJJJGHGIJHJIIIGGHJIJJJJIIJIIJIJIEGHIIJJHHHEFFFDDEDEDDDCCDDDDDDDDDDCCDDEDDDDDDDEDDDDDDD
@3NF
GGAAGATGAAGATTTCGGATTTCGGCTTGTCCCGAGATGTTTATGAAGAGGATTCCTACGTGAAGAGGAGCCAGGGTCGGATTCCAGTTAAATGGATGGC
+
CCBFFFFFHHHGHJJJIJJJJJJJJJJJIIGIJJHHGHIBFIFGIIJIIGHHIJGIJIJIEHHHEDFFEDDDDBDDACDDBDDDEEDDCCDDDDDCCCDD
@3NG
GCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAA
+
CCCFFFFFHGHHHJIJJJIJIJJJJJJJIJJJJJIJJIJJJIJJJIJJIJJIJIJJJIJJIJJJJJJJJHHHHFFFFFEEEEEDDDDDDDDCDDDCDDDD
@3NH
AGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAA
+
??<DDD4+C?CD:C+<A@B+A<C@A?)):1)0:?9?BB9BCBD>@>>CAD<8:.=;(;(6.>A@;,5;;>A>>A(:=????98<<2<>(4:A<8<><??
@3NI
CCTATCACGACAAATCACCGGCCTTCTCCTGACCCCGAGCAGCGGCCCCTCCGGTCCCCCCTGGACAACATGATCCGCCGCCTCTCCCCGGCTGAGAGAGC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJHHFDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDBDDDDDDDDDDDDDDDDDDDDD
@3NJ
TGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCAC
+
@@@DDDDDFBDBFGHB<<?CFHIH@AHHIIGACGIGHEE<@G9DDDD<9?@AA@<ACEEEC@C>DC;ABBBB=@CC@CCCA>C;>CBCCCCACCA>A>C
@3NK
CCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGAC
+
C@CFFFFFHHHHGJJJJJJJJJJJJJJJIJJJJIJJJJJJJJJJIJJJJJIJJJIJJJJJJJIJJHHHHHFFFFFEDDDDDDDDDDDCDDEDDEEEEDDD
@3NL
GTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGCAGGCATATGGGCAACA
+
C@BFFFFFHHHHHJJJIIJJGJJJJIJIIIJJJJGIJGIIJJJJJJJJJJJJHHHFFFFEEEEEECDDDDEDDDDDDDDDDDDDDDDDDDCDEDDDDDDB
@3NM
ACACTGCGTGAGCTGGAGCGCTATGTCACCTCCTGTTTGCGGAAGAAAAGGAAACCTCAAGCTGAGAAAGTTGATGTGATTGCCGGCTCCTCCAAGATGA
+
;?@DDDD?FFFF;FBAG@D@FCFB@?DFFFFFIIIFIFIFFIFIFIIIICEFFFFFDDDDDCCC>@>BBABBBBBB5>ADD>@B=9<BBBBBBBBBB@BA
@3NN
AACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCC
+
?;=DD?DDHDCDCGHIBDAB:@F@CGHCHED?FFH?B;F;CCAGHCFCGE;@AEC==B@??;B;6>;;;>>?C=;(:5>>:A89<@?>CCBBB?<?C:AB
@3NO
CAGTGCGGCGCCTAGAGGGAAAGCGAGAGGGAGACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCA
+
@C@DFDDFFDHHHBGIIIIGHJJJIGGGGGGJGEHHHDFDDDDBD=CDDDDBBB@BD@BDDBBDDDDDDDCCDBBBBDDDDBBDDCDCDDCDDDCCECDC
@3NP
GGAGAATATATTAAAATGTTTATGCGCGGTCGGCCAATTACCATGTTCATTCCTTCCGATGTTGACAACTATGATGACATCAGAACGGAACTGCCTCCTG
+
;8:ABDDBHF?DDEF<A?FEHGH<B?@8:?:?<ABGGHIGAA@FFC9=C@8=CDAH;4-59...;>C;A66@CCDCDCC>@A@@@9?=BBB@4+3>C8CC
@3NQ
CCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCT
+
CCCFFFDFHHHHHJJJJGJJJIJJJJJJGDGHFHJJJIIJ?FGIIJJIJIJJIGJJJJJIJJIJJDHHHHGFFFFDDDDDDDDABDDDDDDEDDDDDDDDD
@3NR
GTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACT
+
?=@DFFFDDHB<CGGBH>C>GGGIIIHHHGHBGHIIGAAGIGHGGIIB@GEHGHIGIIGIIIIIIGFFFEHFBCC?:@CCBCCCCCBCBBBBCB>ACACC
@3NS
TGCTGAAGACAGACATGGAACGTCACATCAACGAGGAGGACACAGTGCCTCTTTCTCACTTTGATGAGAGCATGGCCTACATGCCGGAAGGGGGCTGCTGC
+
CCCFFFFFHHHHHJJJJJJJJJJJIJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHHHHHFFFFFEEEEEDDDDDDDDDDDDDDDDDDDDDD
@3NT
CCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCT
+
@@@DDDDDDHDHAHGGGAHHGHEHIIIIIDDFGHIIGIIIFGII4DHGGIGGHGIIIIIIIIGGIFHHEEFFFDDBCCBBBDBCDDDDDDCEDDDDDDDCD
@3NU
CGGATGGAGAGGCCAGACAACTGCAGCGAGGAGATGTACCGCCTGATGCTGCAATGCTGGAAGCAGGAGCCGGACAAAAGGCCGGTGTTTGCGGACATC
+
@@CFFFFFFADDDIJIIIJJJIIJIIGGIJJIJI@G9BBHIJIGGGEHHGGEEFFFDFFFFEEDCCDDBBDBD=BDDDBDDDDDD>B>BCCCBDBBBDC
@3NV
CCACATACCAACGGCGAGGATCACTTCAGCTCTGGCAGTTTTTGGTAGCTCTTCTGGATGACCCTTCAAATTCTCATTTTATTGCCTGGACTGGTCGAGGC
+
@@@DDDDFDHBDFG@FHEHFCHEHIGIIBB?*?C>B3B==8@CBG=AE>==BCDFDF?@>;@;=5;=C>CCA(>CA;>BDCC;::44:88<@AB:39B<B.
@3NW
CTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTAT
+
CCCFFFFFHHHHHJJJJJJIJJJJJJJJJJJJJJJJJJJJJIJJJJIJJJJJJJJJJJIJJJJJJJJHHHHHHFFFFEEDEEDDDDDDDDDDDDDDDDDDD
@3NX
CGATGCCAAGGGAAGGACGTCCTATGTACCAACGCCAGATGTCTGAGCCAAACATCCCCTTCCCACCACAAGGCTTTAAGCAGGAGTACCACGACCCAGTG
+
=<=?A?A=8AAA+<AA+?3?<?=@A*1??AA<??08=:/*=/))=84)7>AA=AB7AAAA5)77).3;(.5;=(593;:?((558238=3:(29005;=::
@3NY
CCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGA
+
CCCFFDFFHGGHHIIJJJJJJJJJJJJJJJJJGHIJJJJJJJJIJIJJJJJJJIJIJJJJJJJJJHHHHHHHFFFFFFDDDDDDDDDCDEEDD
@3NZ
CAGAACATTGTTCGCTGCATTGGGGTGAGCCTGCAATCCCTGCCCCGGTTCATCCTGCTGGAGCTCATGGCGGGGGGGGACCTCAAATTCTTCCCCCCCGC
+
@@@?DDDDDFDHFGG<GIFA?FA?EHDF;F39DHCDH9BDHAEEHIIG@=;AEHEEE@D>;A6>A;A3>@???0505&&&)83(+4(((:(+((++0005&
@3O0
CCAGCACGCCAGTGTCCCCACTGCATCATGCATCTCCAAACTCAACTCATACACCGAAACCTGACCGGGCCTTCCCAGCTCACCTCCCTCCATCGCAGTCC
+
CCCFFFFDHHHHHIIJJJJJJJIIIJJJHIIIJJIIFIJIJJJJIJJJJJJJIJIJJJJJHHHHHFFDDDDDDDDDDDDDDADDCDDDDDDDDDDDDD@CD
@3O1
CAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCT
+
@CCFFFFDHDFHFIJJIIJJJIJEGIGJJGIJIGIBGIGGIJJIIJGIJIIGFHHIJIJJIGHEHHFEEDCECEEEEDEECEDDDDDDBBDCDDDDDDBD
@3O2
CACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGC
+
CCCFFFFFGHHHHJJJJJJJJJJJJJJJJJJJJJJJIJJJIJJIIJJJJIJJJIJIJJJJJGIJJGHHFHHFFFFFFEEEDEDDDDDDDDDDDDDBDDDDD
@3O3
CACCCAGGGAGCCACCTCCACAGCCCATCATGCCTTCAGTATTCTCTCCAGACAACCCTCTGATGCTCTCTGCTTTCCCCAGCTCACTGTTGGTGACAGGG
+
@C@FFFFFGDHHHJIJIIJJGGHIJJIJJJJIIIJEGHHHEGIJGIGGIIJHJIJJJICGHJJIGHGHHFFDEBEDEEEEE@BCCCDDDCCCD?BDDDD?B
@3O4
ACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGG
+
CCCFFDDDFHHHFJJHIJGGGGIGHIIIIJJJJJJJJJJJJJIJJJJJJIJIIIIIJGIJGEGGIJFIGGHHHFFFFDEECEDDDDDDDDDDDDDDDDDD
@3O5
TACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCT
+
CCCFFFFFHHHHHJJJJJJJJIIIJJJJJHIJJJJJJJIJJJJJIJGHIIGHHHHHHBDFFFEEEEEEDDDDDDDDDDDDDDCFDDDDDDDDDDDDDDDDC
@3O6
CGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTT
+
;;+B;?DDDED?;??DDEE><A+A+3AA?;ECECD>1?D9BDDBD<DDEE@8*?DCBDIA;7A>?@A>66;@>??=;AAA>:9???;>A<83><+2+3:>A
@3O7
ATTCTTATGACCCCCAAGGAGAAGGCAGGGGGGATCCTGATCTGTCCAAGCCTAAAAACCTTGCTCCTTTACAAGAGGGTCAGGAGTCTTACACAACTGGG
+
=??DBB>,=,AADEA)A::<C;33?@)::?)800:?=AAAA>83>AA8>><<99A>:3)29>:AA34>:A4>>A((+()2>233+83>A>AA>:4<+4(9>
@3O8
GGGAGACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTT
+
@CCDFFFFHHHHHHJIIIJJIJJJJJGIJJJGIJJIJIJJJJJIJHHHFFFDDDDDDDDDFDDDDDDD@CCDDBDDDDDDDDBDDDDBBDDDDDDDCCDED
@3O9
CCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGC
+
CCCFDDEDHGDFFGJJIJIGIIIGEHGF@BFGFHGEHHGGFGGGIGIJJIGIEHJCHIHGIGEHGCHHEHGCCDEFFEE@?=@BB?BDDEEEDDDCCCC>A
@3OA
CTCCCTGATTTATGACGACGGCCTCTCAGAGGAGGAGACACCGCTGGTGGACTGTAATAATGCCCCCCTCCCTCGAGCCCTCCCTTCCACATGGATTGAA
+
@<?:BD?DFFFDFIE:E:F<DGA?FBDGF?DE@@@B?8BBFEBFEFF)7?;@;@ADABDABAAB??BBB@BBBB59>BB??B@BBBBBB@@ABBA>@BBA
@3OB
ATTTCTTCATGAAGACCTCACAGTAAAAATAGGTGATTTTGGTCTAGCTACAGAGAAATCTCGATGGAGTGGGTCCCATCAGTTTGAACAGTTGTCTGGAT
+
CCCFFFFFHGHGHJJJJIJJJJIJJIJJIJJJJEGHIJJJJJHJJJJJJJJJIJJIJJIGIJJHIIJIFHGGIAHHHFFFFFFFEEEEEEDDDDDDDDDDD
@3OC
CCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTAT
+
CCCFFFDFFHHDDGIIIEEAHIIGIEHEHGIIFE@FGIIIHHDHIGBHEHCEHEFDDBCCE@CCCDC@CDCDDDDDDDDDD?B@CCDCD8ABBABACCDCD
@3OD
CAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJGJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJIIIHHHHFFDDDDDDDDDDDDDDDDDDDDCDDDCEDD
@3OE
ACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCAC
+
CCCFFFFFHHHGHGHGIIIGIGIHIJJIIIJJJIJGIJIJIJJJIIIIJGHFHIGIIIHHHGFFFFEAECCEDDD;@CC??CCCDD:<ACDDCCDDEDDCD
@3OF
GAGAAAGTGCCTGTGAGGCCCAAGGACCCTGAGGGGGTTCCTCCTCTCCTGGTCTCTCAACAGGCAAAACGGGAGGAGGAGCGCAGCCCAGCTGCCCCACC
+
;==;<A7A4A@7+22?4A1?<7+<7A7:A)??A1A?=AA>B;>73)7)7)=A7)7?3)73;3;=5(;=3;=(,',5((&++8)0999<<(8;??;188809
@3OG
GTCAAAAATTACAGATTCAATTTCAGCAATTACAGGCTAGTGAAACTCTGAGAAACAGCACTCATAGTAGCACAGCTGCAGACTTACTACAAGCCAAACA
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJIIIHIJJJJJJJJJJJJJIIJJIJJJJGJJHJJJGIJJJJHHHHHFFFFFFEDEEDDDDDDBD
@3OH
GAGAAAGGAATTATGCAAAAGCTGGCTGGAGAGAGATATGTCTATACGTTTGTGCGTGATCCAGAAGCCCTTTCCTCCATGGCCTTTCCAGGTAATCAGCG
+
;<18=)6=@7.69:1>4949@()=:5>;=??73(15):8>.<:))0)00:=;(.)-(--3;818333=>===)388;59(.(7;70496(,(,(,(,,5(8
@3OI
CAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGC
+
@@@DDDDDHBH?FHGEGEE@FFBA;FHBGGDFGIIGGIGGIIIIIGIIIIIIIIIIIIIIIIIGGHHHEDDECCCCCCCCCECCCCCCCCCCCCCCCECB
@3OJ
CCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGC
+
+:?=DD<BDDDBB@<DCBFED?A2<<?<*:??*:?CD<?;93?9?DID@DDID@B886@CCDIIC?==?=7;7;@>@??=???>A>35:9AA>>>A<8><<
@3OK
CCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTAT
+
@@@DDFBBFHDBB<GHFDBH<DEABHF:F;?;FHBBGGDAFGEHEHIEH@CHEH?B;@CACAC@C>C>5>;C<A?<??BA?AA:@>@@??C??BBB??C>A
@3OL
CAAATCAAAGCTCATGATGGCAGTGTGTTCACACTTTGTCAGATGAGAAATGGGATGTTATTAACTGGAGGAGGGAAAGACAGAAAAATAATTCTGTGGG
+
CCCFFFFFHGGHHDIIHIIJJJJGJEFHHHIIIGHIJJHIJIIIHIJHJJIHIICHHHJIJJJJIJIJGHIGHHGFFFFEEECCDDDD?CCDD>CDDDDD
@3OM
GGAAAAGAAAAAAAGAAAAGCACAAAAGGAAAGAGGAAGTGGAAGAGAATAAAAAAAGCAAAGCCAAGGAACCTCCTCCTAAAAAGACGAAGAAAAATAAT
+
@@CFFFFBFHGGGGIGIJIJGGHHEDHIEGHIEFGGIIC8BEHGECDFHIEGIIHFDDCDDDDDDDDDBDDDDDDDCCCDCDDDDBDDDBD?BCDDDDDD>
@3ON
TGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAAT
+
CCCFFFFF8FHHHIJJJJJJJIJJJJJJJGIJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJHHHFFFFEEEEEDDDDDDDDDDDDDDDDDDCDEDE
@3OO
CTTGTGCCCAGCAATCAGGTGGTCGTACAAACTGCATCAGGAGATATGCAAACATATCAGATCCGAACTACACCTTCAGCTACTTCTCTGCCACAAACTGT
+
CCCFFFFFHHHHHJJJJJJDHIHHJGHJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJHHHFFFFFEEEEEEDDDDDDDDDDDDDDDDDDDDC
@3OP
CGAGTTGCAGTCCTGGAAAATCAAAATAAAACTCTAATAGAAGAGTTAAAAACTTTGAAGGATCTTTATTCCAATAAAAGTGTTTGATTCCTAAGAAAGA
+
@@@DBDBAD>HHFBFEG?BGHECCH>HHIEH<CFHCE>GH@BGCF:DDEDCH@DFCHGGIEA3CFHGGIGGIIECGE@EE.=7?CCCDFDCACCCC;CAC
@3OQ
CAATCTGATTCTATAGAAGACCCTAACAGTCCAGCAGGAAGAAGGCATTTGCAGCTCCAGACTCAATTAGAACAGCTCCAAGAAGAAACATTCAGACT
+
?@@DDFFDHHHFDHIIEIGGGDHGIIIGIEHGDGGGHHCGHHGIFIEEGHIIIIIGIIGHIIGIHIHIIGGIEHAEFCDEFEFECEEDDCCDDDCAAC
@3OR
GTGCCCGCCCCTCTAAGCCCGGAGCCCGGCGCTTTCCCCGCAAGATGGACGGTTTCGCCGGCAGTCTCGATGATAGTATTTCTGCTGCAAGTACTTCTGAT
+
@BBFFFFFHHHHHIIJJJJJJJIJJJJJJJJHGHHFFFFDCDDBDDDDCCDD@BBDBDBDDDDDDDDCDACDCDEDCDEEECDDCDDACCDCCDDCCCDAD
@3OS
CAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCTTCCCACTAGTTACCCACCCC
+
C@@FFFFFHHFFHIJJJJIIJIHGJGGGIJIIGIGHIJJIIIHIFHIJJJJJIHIIGJJJJEHHEHFFFFFDDEDBBDD5>CDCD@BDCCDDCCDDBDDD
@3OT
GAAGCTGGGCCGCGTGGTGCACATCATCCAGTCACGGGAGCCCTCCCTGAAGAATTCCAACCCCGACGAGATTGAAATCGACTTTGAGACCCTGAAGCCGT
+
C@CDDDDDHFFHFIGIICCFHHIJIJJJGIJFGHIJGIEGHGIFHHGFFFFFCEEDEEDDDDDDB?BDBD>BDDDDDCCD?@BDDC@??CDA??<>CAA<9
@3OU
CAAGCCCTCGAGCAGTTATTCCCATGTCCTGTATAACCAATGGAAGTGGTGCAAACAGAAAACCAAGTCATACCAGTGCTGTCTCAATTGCAGGAAAAGA
+
@@@DFFFFHHGHHIIHIIIIIC>HCGDFHEGHIFIIGHIAHIFHEH?FHBCHIIIIIGIGIGGHIGEAEHFHHFFF@DCDCCEDCDDDEDCDDDDDCDDD
@3OV
ATTTTAATCATGAGATTTTTGGACAGCAAAATAATGACTTTACCCCTCCTGATGTGAACCTTTTTGGGGGGCATTTTGATGCAGCAGAGCTTGGGAGGGTG
+
;1;(8)=)))))..)):@?1(8))333)=@)9.;))))1<?))9=(7(<)))03)/)8)9)<)8>'5=?'0&)+6(+((+(((+(+(((+(8+6(2(0&(+
@3OW
CTGACCGGGGAAACCCGGGGGCCAGAGGCCCACAGCGAGAGGAGAAATAGGAATCTCTGTGAGGGCAGAAACCGCCAGGGGGCGTGGCACGTCTCTCAG
+
+1:++2)0<)))++1:))))-'-((6=;,5(55(,(,',8&+((((((((+((33((+88(3(++0(&+((+(&&)&&+050&&09-&((&(+(+4:(+
@3OX
CTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATG
+
CCCFFFFFHHFHHHIJGIIJGIGGGEGHJIJIIDHIIJIJJJIJJIJIJIHHFHFFFFFDEEEECDDDDDDDDDDDDDDCDDDDDEDDDDDDDDDDDDDDD
@3OY
GGAGCACAAGACAGTCCGACTCATCTAGAGATGATGGAAAGTGAGTTGGCTGGGAAGCAGCATGAGATTGAAGAGCTAAACAGAGAGCTGGAAGAAATG
+
?@8?7D8D;DHFBBFDFBEHEI@B9?999D?9?*:?B9DGGGG4DBD?BDECAF9=@ECC;=@CC>E:>CCEE@@;>@>6>3;;;;;<:5<(>C@CCCC
@3OZ
ATTGAATTCCTGAAGGAGGCACATCTGATGAGCAAATTTAATCATCCCAACATTCTGAAGCAGCTTGGAGTTTGTCTGCTGAATGAACCCCAATACATTAT
+
@@CFFFFFHFFH>HBEHIJGHGGGGIIHIJJIJIIIJIJJJJIIJJJGIIICEHGIIEHIIJICGGHG3CGGFGEHHHEFFFDFCEDEDDDDDDDCDCDDD
@3P0
GAGGTAACCAAGCGAGAGAAATTAGAGCTGTCACAGAGACTGTCTGATCTTTCTGAACAATTGAAACAGAAACATGGTGAGATTAGTTTTCTAAATGA
+
=?@D=BDBFDHDHIDGGHIIGIGHBHIIEE?<DDDF>BFDHGIIIGHIGGHGIGCHIIGCHGIIDGECGDEH>7=?;..?@:@@@>;>CA>ADC;>>:
@3P1
CTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGC
+
C@CFFFFFHGHHGDEGIJJJIJJJJJJJJJJJJJJIJJIFIIIJFIJJJJJJHGHHHGFFFFFDCC6@CDCDDDBBDDDDDDDBDDDDDDDDDCDDDDDD
@3P2
GGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACAC
+
@@@DDDDFHFHDHJGBHEHFHIGGHGJGIGIIJJJJIIJJJFGGGGDGGGIIJJI<B@FIIIJEHGAGEHEHH@DDEFDCCCCDCCDCCDACDDDDDCDD
@3P3
CTTCCACCCACATGCCAAGGCAATCTCCTTATCATGGGGACTGAGGATGCCTCCTCCTTGCCTGAAGCCAGTCAAGAGGCAGGGAGCAGAGGCAATTCCTT
+
:+14AD?DD1B12+<++2<?3C92994C?E:EDEEE936B@D@39(/**(=CBCDDA)>AAC.).7))==6.)).63>=;5=/'582((,208(8>>4>>>
@3P4
TGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJIJJJJJJHJJJJJJJJJJJJJIJJJJIJJJIJJHHHHHFFFFFFEDEDDDDDDDDDDDDEDDDDDDD
@3P5
TGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCT
+
@C@FFFFFHDHHHJIJJJIJJIIIJJJJJJIIJJJIHJJJIJJJIJJJGJJJIIIIJJJJJIJIJJJIHHHHHGFFFFFFEEEE@CDDDDDDDDDDDDDDD
@3P6
ACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCA
+
?@@DDADFBFFDHIJIHIGHGGHGCGGGGGIIJDGHIJJJIFHG?FGGHJIHIIJIJJGHJJJGFCEABDDFDFEEDDDDDBBDCCDDACCCCDDDDDD
@3P7
GCACACGCGTGATCCAGCTGATGCCCAGCCCCATCATGCACCCTCTGATCCTGAACCCCCGGCACTCCGTGGATTTCAAACAGTCCAGGCTCTCCGAGGAC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJHHFDDDDDDDDDBBDBDDDDEDDDDDCDDDDDDDDDDDDDDDDD
@3P8
CGAAACCTGACCGGGCCTTCCCAGCTCACCTCCCTCCATCGCAGTCCATACCAGATAGCAGCTACCCCATGGACCACAGATTTCGCCGCCAGCTTTCTGA
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHIJJJJJJHHHHHFFFFFEEEEEDDDDDDDDDDBDDDDDDDDDDDDDDDDDDDDDE
@3P9
GCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAA
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJHHHHFFFFFEEEEEDDDDDDDDDDDBDDDDD
@3PA
AAAAAAGAAAAGCACAAAAGGAAAGAGGAAGTGGAAGAGAATAAAAAAAGCAAAGCCAAGGAACCTCCTCCTAAAAAGACGAAGAAAAATAATAGCAGCA
+
@@@FFFFDHH?FHIGGIDGGIDGHIHGIHIBDFDEFDGGGIIJIJIIIIFEEHEEFFFFDDDCDDDDDDDDCC@CDDDDDDDDDDDDDB?CC@CCCC>AD
@3PB
GACAAATTCAGGCAGTACTCAGCAAGGTACAACTATTCTTCAGTATGCACAGACCTCTGATGGACAGCAGATACTTGTGCCCAGCAATCAGGTGGTCGTAC
+
@@CDFFFFHHFHF@FGGHGGHGHGIJJGHJJJJIEFIIJJJJIIGGIJJIIADHHIJEHEBHIJDEIJIGICHGGIFAEHHFC(.;ACECCC;@@3;=8?<
@3PC
CACGAAGAAGAGCTTTCCAAACTGAAGGAAGATTTAGAAATTGAACATCGAATAAATATTGAAAAACTTAAAGATAATTTAGGCATTCACTATAAACAGC
+
@@CFDDDDHHGHHGIJJGGFGIIIGIGJIGIGHHIHIJJIGIIJJJJGIJJJIJJJJIIIIJJJIGHIJJJGHGHHGHFFFFFFEEEEEEDDDDDEDDDD
@3PD
CAAGTTTGTGTGTGATCCAGAAGCCCTTTTCTCCATGGCCTTTCCAGATAATCAGCGTCCACTGCTGAAGACAGACATGGAACTTCACATCAACGAGGAGG
+
;@@=DAA?F8FF:CCGG<AA?BEGEF@G>?<9??F?C;D?CFBB??93??4999DF<CB@F>F;C=;7=@=7ACA?BD@;A36(.>5>B;ABBB??2=28.
@3PE
CAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTAAAGTTATCCCCAGGTACCTG
+
@@@FDFDDGGFBHGGIIIIIHGIEGGGIIIIGIIGGGGIGGFFFHGGFHIEGIHCEHFFEFEEEEDDCDDDDBCA>CCA@CDDDBCDDDDCDDDB>ACCCC
@3PF
GGAAGCCCTGCTCATCAGCAAATTCAACCACCAGAACATTGTTCGCTGCATTGGGGTGAGCCTGCAATCCCTGCCCCGGTTCATCCTGCTGGAGCTCATGG
+
=<=A+?A8=7+2<@?7@+?BAB??CCCBA;A11:AB3*?*00*:)4((.9)83)=A-5>A9>A@@3)6>;>55;=====850;??;8=3:;(8;;1:;;;:
@3PG
CTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCT
+
?@;AB+=ADF;FF:<CFAFFEFBCFFFDFIEF?BFFFFBEFCDFF?DFBFA;@FEDFIEDEECE1?2@?C@@?.=BAB(5@@>95<@BBBBBBB433::9A
@3PH
CACAACACCATGGTTGGCAGTGCGGCCAGCCAAAGCTTTCCCCCTCCTCTGATGATTAAACAGGAACCCAGAGATTTTGCATATGACTCAGAAGTGCCT
+
@@CFFFFFHHHHHGHIJJJJHIJJJIIJJJJJJJJJJJJJJJJJJJJIJJJHHHHHHHFFFFFDEEEDDDDDDDDDDDDDEEDDEEDCCDDDDDCCDDD
@3PI
CTATTCTTCAGTATGCACAGACCTCTGATGGACAGCAGATACTTGTGCCCAGCAATCAGGTGGTCGTACAAACTGCATCAGGAGATATGCAAACATATC
+
:?1AAA;D:C:D<E>A?+CCFDFABC@FEIA;<:?3?D?:?C?DD:99B99BDIC?@D@38BC-=;'(65=?A).?7)77;AA@>3>>>BDAA<<AA>>
@3PJ
TGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACAC
+
CC@FFFFFGHFFFIIJJIHIJJJIJIJJJGICHGJJIIIFJIGIIIIIIJJJJJIJJIIIJJJJIJFIHHHHFFFDFFEDDEDDDDDDDCCDEEDDDDDDD
@3PK
CAGCGTAGAGTCGCTGGAGCGGGCGGAGCTGTGCGAGAGCCTCCTCACTTGGAGATCCTGCATATTTTGATGAAAATTGGCTAAACAGAATCAAAACTGA
+
CCCFFFFFHHHHHJJJJJJIJJJJJJHFFFECEDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDEEEDDDDEDDDDDDDDDDDDDDDCDDDDDDDDDD>
@3PL
GAAGCCGTCCACACTGCGTGAGCTGGAGCGCTATGTCACCTCCTGTTTGCGGAAGAAAAGGAAACCTCAAGCTGAGAAAGTTGATGTGATTGCCGGCTCCT
+
CCCFFFFFHGHHHJJJJJHJIJJJJJJJJJJJJJJGJJJIJJJJJHJJJJIJHFFFFEEEDDDDDDDDDDDDDDCBDDDDDDDDDDCDEDEDDDDDDDDDD
@3PM
GGCTTCTCGTCCTCAGAGTCGGAGAGCTCCAGTGAGTCCAGCTCCTCTGACAGCGAAGACTCCGAAACAGAGATGGCTCCGAAGGCAAAAAAGAAGGGGC
+
@@@DDFFFFFHHFIIFGICHHIGH8DHGGIGHFHFHGGICHHCBFHGIIIDHIIG;AHBHCEFD>ABBCCCC9CCCACABB>@B&+<ABC?<<(<A@<@B
@3PN
CGTGCTGAGACATTCTTCTGATAAAGTATCTAAACTAGAAGGTCAAGTAGAATCTTATAAAAAGAAGCTAGAAGACCTTGGTGATTTAAGGCGGCAGGTT
+
:?:B=;A?+<?DFBBGG>HGIGCCBHIIB<?EHB?EGE>?CB;:DFG<BBGHIIGG@HIIC@8@;B=8@FCHGEGGEGEHF3?=;?3;BCECCBB?>@BC
@3PO
CAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTACGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGAC
+
@@@FFFEFHHHHHIJJJDHIIIJJJJJIIJIIIJIIJJIII9?FHGGIJJJGIGIEHGHFFHGEDDEFFEE?@CABDDCDDDBDDDDDDDDDCDCDBCD@B
@3PP
CCTGTACAATGTCAGTGCCTATGATCAGAAGCCACAAGTGGGAATGAGGCCCTCCAACCCCCCCACACCATCCAGCACGCCAGTGTCCCCACTGCATCATG
+
CCCFFFFFHHHHHJJIJJIJJJJJJJJJJIJJJJJJJJGIIJJJJJJJJJIJJJJJJJJJJJHDDDDDDDDDDCCDDD:@BDDDDDCDDDDDDDDDDDDDD
@3PQ
ATAATTACATGCGGCAAATCTCATATTTTCTTCTGGACCTGGAGCGGCAATTCACTAACAAGAAAACAGGGAATTTTTGGGAAATATGAAAAGCCAAAATT
+
8?8DD;A:=A:C@8)1@A<F<F<FEFGD9:D??F?::?9???B8)?FA;;=D@C;=A>?7@BDBA>665?;5=9::::?=8?B8434:>AA>+++3+(2:4
@3PR
GGACACACCATGCTCCCCATTCGCTGGATGCCTCCTGAAAGCATCATGTACCGGAAGTTCACTACAGAGAGTGATGTATGGAGCTTCGGGGTGATCCTCTG
+
=@?:=B=@:AFH>GHGIDCC?AACF@A8?CBFHIBD90???;FG?DFH9D?8AG@AA@C@GH>?777@?DBCCC;>C;B>CC=5;A>=BB<05@C>>:AA>
@3PS
TGTCCAAAAGCCATGAAGAGATTAATGGCAGAGTGCCTCAAAAAGAAAAGAGATGAGAGACCACTCTTTCCCCAAATTCTCGCCTCTATTGAGCTGCTGGC
+
@B?DDFFFHHHHGGIHIJJJIIJJJCGGIIJIE?EHIJJJJJIJJIJJJJJJJJJIIIBHIIJIJJJHHHHHGFFFFFEEEDDDDDDDDDC>@CDDDDDCD
@3PT
ATGAATTGATGACTGGACAGTTACCTTATTCAAACATCAACAACAGGGACCAGATAATTTTTATGGTGGGACGAGGATACCTGTCTCCAGATCTCAGTA
+
@@@DDDDDFFHBDHJEDBFFFEHGHGHHGIIGGIJJGHHJGGIHEFC=?FFHIJEIGIGIGGIGGE=FGAAHDDCAD;ACDCD:>CCDC::>C@CCDDC
@3PU
CCTAATCACAGCAGTCCTACTTCTCCTATCTCTCCCAGTCCTAGCTGCTGGCATCACTATACTACTAACAGACCGCAACCTCAACACCACCTTCTTCGACC
+
:::B;D>DF>FFFF@E:<@<CEAF:FCA9FHFACGGBB9:D4?FD>FG>DB)99?DC4?BBF4=B=@CFF8@@(',9BCCC=>ABB@?@BB(,>AAB2229
@3PV
AGGACCCGGATGTAATCAACACCGCTTTGCCGATAGAATATGGTCCACTTGTGGAAGAGGAAGAGAAAGTGCCTGTGAGGCCCAAGGACCCTGAGGGGGTT
+
CCCFFFFFHHHHHIJJJIJJJJJJIJJJIGIJJJJJIJJJJJJHIJJIJJIDEHAHFDDFDEEEEDDDDACDDDDACDDDDDDDDDDBDDDDDDDDDDD<B
@3PW
CAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTC
+
@@@FFFFEHFHFHIJEGHGGJJJIJIIHIGIIJJJJIJJIIGJJGIJIJGIIFHIIJJJJJJJIJHHGFFFFFEEEEEECCDDDCCDDDDDDDDDDDDDD
@3PX
GGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACAC
+
CCCFFFFFHHGHHJJJJJJJJJJJJJJJHIJJJJJJIIJJJJJIJJJJIJJIJJJHJJJJJJIJJIJJHHHHHFFFFFDDEEDDDDDDDDDEEDDDDDDD
@3PY
GATGAAGTAAAAAGAGAATGATCTTCAAGAAAAATTTGCACAACTTGAAGCAGAGAATAGCATTCTTAAAGATGAAAAGAAAACCCTTGAAGACATTTTG
+
1:==DDBD?DDDDEE3EE<+A<?C?<FCCFFDC3:CD?C41:??B?B39*098;DDCDA=>=8=@ACCDACD)7ADC@AADDDDD?@;(;3(5;;;(5;>
@3PZ
GAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGAC
+
@@@FDFFFHDDFHIJEGIJIEGIJJGIIGIGEHI>EHFHHHCHGJIGIJIHG@?ABBDEFEA6>>@CDDCDDBDDDDD@?BDDBCCCDDDDCD@CCCDDDD
@3Q0
GCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATAC
+
@C@FFFFFHFHHHJIGIJJEIIIGHIJJJJGJJJJIGJJIJJIIGGHIEHHHHIGCEHHHFFFFFEEEEEDDDDAAAD>C?BBDDDDDD>@@CDCCCDDED
@3Q1
ATGTGGCCTCAGTGAAACAATCAGTCTCAAGTAAAGGCCAACCAAGCCCTCGAGCAGTTATTCCCATGTCCTGTATAACCAATGGAAGGGGTGCAAAC
+
9<1<=)<().41>:<?1)2();?;.))2)84@8=6))(191=/6?<;5><?37-;9)>:);3>;39>7)8>6;68;==;73=;;(-9((,/',2(5:5
@3Q2
GGACAAGGCTTGCAGCCAATTTACTGGAGCAGGGATGACGTAGCCCAGTGGCTCAAGTGGGCTGAAAATGAGTTTTCTTTAAGGCCAATTGACAGCAACAC
+
?@?DDDABFDBFFHBFFBEEFHDEHEHB@BDE=:??FH<D???BBDGD=F;1=FGEAGHGGC>E;;B?;BEC6>CC>@CC;;;;C9<BCCC>CCA<9<??@
@3Q3
CCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCG
+
CCCFFFFFHHHHHJJJJIJJJIJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJIIIHGHFFFFFEEDEDDDDDDDDDDDDDDDDDDDDD
@3Q4
CCAAAATTTGTGCAGTGTTTAGCATTCTTGGGGAATGGAGATGTTCTTACTGGAGACTCAGGTGGAGTCATGCTTATATGGAGCAAAACTACTGTAGAGCC
+
CCCFFFFFHHHHHJJIJJIJJJIJJJJJJJJJJJJJJJJIJJJIJJJJJJJJJIJJJJJJJJCGIIJGIJJJHHHHHHHFFFFFDEEEEDDDDDDDDEDDD
@3Q5
AGAGTCGGAGAGCTCCAGTGAGTCCAGCTCCTCTGACAGCGAAGACTCCGAAACAGAGATGGCTCCGAAGTCAAAAAAGAAGGGGCACCCCGGGAGGGAGC
+
@@BFDEFFHHHHHJJJJJJJJJJJJJIJJIJJJJJJJJJJJJJJJJJJJJJJJHHHFFFFFFEEEDDDDDBDEDDDDDDDDDDDDDDDDDDDDDDDDDDDB
@3Q6
GAAACCTCAAGCTGAGAAAGTTGATGTGATTGCCGGCTCCTCCAAGATGAAGGGCTTCTCGTCCTCAGAGTCGGAGAGCTCCAGTGAGTCCAGCTCCTCTG
+
CCCFFFFFHHHHHIJJHHIJHHJJGJIJJIJJJJJJJJIIJJIJJJIGIJIJJJIJJIIEIHHHHFFFFFDEDDBB=BBDDDDDCDCDDDDDCCCDDCDCC
@3Q7
ATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCA
+
CCCFFFFFHHHFHJJIJJJIJJJJJJJIIIJJJJJJJJJJJJJGHIJIJJJJJIIJHHDFFFDDEEDDDDDDDDDDEDDDDDDDDDDDDDDDDDDEDDDD
@3Q8
GGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGC
+
@C@FFFFFHH8FB@BGBGIIIIIIIDBGHHGGBFGIEHIIIFGEGGHIIGIICHGHEHGEGIGHFFHFDEFECECEC@CDCCDCE>@C:?<BBC:>C?B
@3Q9
GAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACC
+
CCCFFFFFHHHHHJJJIHIJJJJJIIJJJJJJIIJJJIIJJJIJJJJJJJJJHHHFFFFFDEDEEEEDDDDDDDDDDDDDDDDDDDDDDDDDDEDDDDDD
@3QA
CCACCCCTCAACCCCTGTTTTCCCCTGCCTTCCTTGCAGAGGCCATGGAGGACGAGGAGAGACAGAAGAAGCTGGAGGCCGGCAAAGCCAAGATTGAAGA
+
@@@DDDDDFHHFHG@?FFHHGIIIIFFIIDBHGBHI>GHDFHIGFGGGCFB;FHIHFEE9;;@CCCCCCCC<@CC99?B?BBBBBBCCBCCBBCCCCA@C
@3QB
GTTGCTTTAATGGAAACGAAGAACCGAGAAGGGTTAAACTATATGGTACTTGCTAAAGAATGTGGCCAAGGTGAAGAAAAGTCTGAGGGTCCTCGAGGCTC
+
++:ABDBBDC4C4+A::A)+38C9<11:C)1:?888B???/??4?*>B<BBC=8=)..)67).=CC2;=;?)7((6(.;55-;;>(5<=859>>'05>982
@3QC
CGATGCCAAGGGAAGGACGTCCTATGTACCAACGCCAGATGTCTGAGCCAAACATCCCCTTCCCACCACAAGGCTTTAAGCAGGAGTACCACGACCCAGTG
+
CCCFFFFFHHHHHJIJJIJJIJJJJJIIJJJJIJJJIJJJJIIIIIJJJJJJIJJJJHHHHFFFFFDDDDDDDDDDDDDDDDDDBD?ACDDDDDDDDDDCD
@3QD
AGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACT
+
@??DDFDEHHFHDGFHJIIJJJIIIGGIEHGHIIIIIGB@GIEHGIGIJJFGGIIIEG@DDHEEHHHACEDFFFEEECCDDCDDCDBDBBDDBBCCDDDDD
@3QE
GGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATAC
+
CCCFFFFFHHHHHHJJJIJGJJJJJJIJJJJIJJJJIJJJIJIIIJGJJIJJJJJJJJJJJHGFFFFEEEDDEEDDDDDDDDC@BDDDDDCDBDDCCDDEC
@3QF
CGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTC
+
CCCFFFFFHHHHHJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJIJJJJJJIJJJJJJJJIHHHHFFFFFDDDDDDDDDDDDDDDDDDCDDDDDDDDDD
@3QG
CGCAGAAAGAAGAAAGAATATGTGAAATGCCTGGAAAACCGAGTTGCAGTCCTGGAAAATCAAAATAAAACTCTAATAGAAGAGTTAAAAACTTTGAAGG
+
@@?DF??DCHDAFIIGIDHCHFC<HFFEDHECF@GDFCGHGIH6BFHGCHI>BBDAD@@CCDD@E@AHH;=C;;;CE;?>@>6;CDCDFCC:CCAA>>>>
@3QH
ATGAACTATGATAAACTTAGCCGTTCACTCCGCTATTACTATGAGAAAGGAATTATGCAAAAGGTGGCTGGAGAGAGATATGTCTACAAGTTTGTGTGTG
+
@@@FFFDFHHBBDHIIIIIG<FGEECEHHIIGGGGADHIDGGIIEIGGGBGEHIIIIGIGHIEHCDADHHGEEEEBB?ACE;;>@CDD@CCCECDD?<AB
@3QI
TCAGTTTCTAAAGTAAATAAAAGTTTTGGTGAAGAATCAAAAATAATGGTGGAAGATAAAGTTTCTTTTGAAAATATGACTGTTGGAGAAGAAAGTAAGC
+
@CCFFFFFHHHHHHIJJJJJJJJIJJJJIFGIJJJJJJJJIJJJJJJJJFHIJJJJJJJJIHGJHIIJIJJJJJJJJJHHHHHHFFFFFEEEEEDCCDDD
@3QJ
GGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGG
+
@CCFFFFFHHHHHJJJJJJIJJJJJJIJJJJIJJJIJIJJJJJIJJJJJJJJHHHHFHHFFFFFDDDDDDDDDDDDDDDDDDDDDDDEDDDDDDDDDDDDD
@3QK
TTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGC
+
@@@DADDDHHFDHJGGIIIHDGHC>EEHGIGGEGGIJGGDGIIIIG:FFFDGGI@E>CDAAEDAEEAA??@B>CCECEECCDD;ACCDCCDCCDBDB@?<A
@3QL
GAAAAATTCGATGGAGACATCAAACAAGAGCCAGGAATGTATCGGGAAGGACCCACATACCAACGGCGAGGATCACTTCAGCTCTGGCAGTTTTTGGTAGC
+
?<<DBD8AADDADE@E@1BD3C>DC;3C@ED?;DDCDCE<D>DDDD6@CDC8=161;A>3?AC?DD>?8??93(89>:::::>:>>>43<(+(:<>?8>A>
@3QM
GTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTAC
+
CBCFFFFFHHHHHJJJJJJJJJJJGIJJJJJJIJJJJJJJJIJJJJJJJJJJHHJIIJJJGGHHHHHHFFFFEEEEEEDDDDDDDDDDDDDDDDDDDCDED
@3QN
GGAGACATCAAACAAGAGCCAGGAATGTATCGGGAAGGACCCACATACCAACGGCGAGGATCACTTCAGCTCTGGCAGTTTTTGGTAGCTCTTCTGGATG
+
?<@DDFDFHFHGHJJJGGJJJJGGIJI?EFGBGIAGIJJBH@GCHBE<BHHGJIDBDDDBDCADCDDCADDDDDDCCB3@CDDBD8@CCCCDCCCCC>CC
@3QO
TTAAAGGATGGGCAAACAGGAGGGAGACTGGAGCGACCAAGAAATGGTCCTGATGATCTGTGGAATTTAATGACCCAGTGCTGGGCGCAAGAACCCGACC
+
1:=AA7+?C>+=AAABBCBC>AAA8A8:*=?9?;)8.'-.==>7))77=77>))..)).;)7>;>6;(6;(;5;;;9;(:5;=?=5&)05;33(+05559
@3QP
CCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGT
+
C@@FFFFFDHHGHJJGIIIGHIJJJIJJJGHJIJIJJJIJJJIGJJIJJGHIH?ECHHFFFFBCCCEEEDDDDCCDDCDBDBDDDDDDDDDDDDDDCBDDC
@3QQ
ATCAACCTCTCTCATCGGGAAGACCTGGCTTACATGAACCACATCATGGTCTCTGTCTCCCCGCCTGAAGAGCACGCCATGCCCATTGGGAGAATAGC
+
@CCFFFBFHHDHDGGIJJFDGIGIIJJJFIIIIAFHCGHIIIIIGGIJI8==BHFHIG;;FEHGFFFFECCEECBDDB=BCDCDC?CCCDB?BBCDDC
@3QR
AAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTAC
+
CCCFFFFFHHHHHJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJFHIIJJJJGHGHFFFFDEECDDDDDDDDDDDDDCCDDEDDDDEDDEDDDDDDDCDD
@3QS
ACCAGATAGCAGCTACCCCATGGACCACAGATTTCGCCGCCAGCTTTCTGAACCCTGTAACTCCTTTCCTCCTTTGCCGACGATGCCAAGGGAAGGACGTC
+
@@@DDBDDFFDHHAFIIICHH9CEF>DHEGG@GHAFHHIHGIEEHGE@HG@EHIA=C?HCABDDDCCCCCCCCC>>CCB?@B3<BB<:CBBBBBB@@B>9@
@3QT
CTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGG
+
BBCFDFFFHHHHHJJJJIJJJJJJJJJJJJIJJJJJJJJJJJJIJJIJJJJJJJJJJJJJJJJJJJJJJHHHHHHFFFFFCEEEEDDDDDDDDDDCDDDDD
@3QU
ACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCT
+
@??DDA?DF?B<2C<AB@GHIBCHIG@HIED=CA?GB?FD@@BFB@GCH=2C=C=777);;;7?@(;;.;@@3;A>>;A;;>>CB?<<4>@ACCBBB<@?
@3QV
TAGAAATTGAACATCGAATAAATATTGAAAAACTTAAAGATAATTTAGGCATTCACTATAAACAGCAGATAGATGGTTTACAGAATGAAATGAGTCAAA
+
@<@DFDFFBDHHFHHGIIJIGIIJJG>EHEHDHGIIJG<GDHIJIIIEEGIGGHIGCHGIIICHJCHGAHEG==EHGIHEEHHEC@DFDDEECCEECCD
@3QW
GACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTG
+
CCCFFFFFHHHHHJJIJIJIJJJJJJJJJIJJJJIJIJJJJJJJJIJJGJJIIJJIJJHHHHHHFFFFFFEEEEEDDDDDDDDDDDBDCDDDDDDDDDDDD
@3QX
CAGATTTCGCCGCCAGCTTTCTGAACCCTGTAACTCCTTTCCTCCTTTGCCGACGATGCCAAGGGAAGGACGTCCTATGTACCAACGCCAGATGTCAGAGC
+
:11+=:DD3C:8D@:C+9C:CE?B>*??D900:900??*/?D<B/8=.B=@8ADA'5;;>3>;???=>75<8,,28:>A4++::>>859>-<4>(:(+(49
@3QY
AAACAGGCCAGCTATGAACTATGATAAACTTAGCCGTTCACTCCGCTATTACTATGAGAAAGGAATTATGCAAAAGGTGGCTGGAGAGAGATATGTCTAC
+
@@@DDD?AFHHDHEHBGHHGG9FHIGIGC>AHGEEGCFCGGEEDBGGDFCHDEGGAG4.=F>9@E;@E=?>AHECEB);A>A=>A=????15:@ADCDCA
@3QZ
GCCTCTTTCTCACTTTGATGAGAGCATGGCCTACATGCAGGAAGGGGGCTGCTGCAACCCCCACCCCTACAACGAAGGCTACGTGTATTAACACAAGTGAC
+
@@@FFDFDFDBDFEB?EGGIH@ADEFAF9CFBHAFHGG3?FGIGAEEG6;@@7@>A@EEEFBCCCBBBBBCCC=B<<58>@9<293?>BDE@CC8?ACAC@
@3R0
GGACAGAGAGAAAAAAAAGAGGAATCTCATTCTAATGATCAAAGTCCACAAATTCGAGCATCACCTTCTCCCCAGCCCTCTTCACAACCTCTCCAAATAC
+
@@@DDDDDAFFBBBEHGGBBFGG@@B@BFDBEHICDDBB*BCAF)=CFGCGGG9)@:=B6)7;?DCCCCCC?BC??@BCBCCCDCCCBBCCCCCCCC3>@
@3R1
TCATCAACCAAGAAGGAGAATATATTAAAATGTTTATGCGCGGTCGGCCAATTACCATGTTCATTCCTTCCGATGTTGACAACTATGATGACATCAGAACG
+
@@@FFFBDFHHHHJIGIJHIIJEHIJIJIGGGEFIIEGEDHGBFHGIIJJIFHHHHEFFEDDBBCEEEEEEBDBBBDDCCCDACCDDDECCACACDDDDC@
@3R2
AGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCT
+
8:=A??D?CDDFFEGHFHICAFEHHG<FECECC@CCFI@?1:BGIIEHBBFDBDCDGIEC@CFCA2@G>?HC>>;BDD@AACCCCCCBBAB?CC@BCCBC
@3R3
TGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAAT
+
@@@DFFADBBFHCBBFHGHHHAF?H?<FG3??CEFE9CADBFDGBD9GCBFHDIGHDHGCHIIBHHHHHFFDFECEE@CCCCCACBBCAB>CACCCCAC@>
@3R4
GCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACC
+
@@@DFFDEHHHHHIGIIIIIIIIBHHIIIIGHIGEFHGCCDFHIIGIGHGIGHI@GHIACHIGEHH==EEFFFEEDA6@>@CDDDDDDDC?BBDBDDDDD
@3R5
CCCAACGACCCAAGCCCCCTGCAAGTGGCTGTGAAGACGCTGCCTGAAGTGTGCTCTGAACAGGACGAACTGGATTTCCTCATGGAAGCCCTGATCATC
+
@@@DD?BB@@FDFEHIHGIGBHEDBHGHE?FHB?F<FGDG:FAFAGEHCGD?.7?=CHFFE7;;.;;9>B<:>>@AC@AC@CA>34@+2<?C<9ACCCC
@3R6
TATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTC
+
@@@DADBDDBFHBHAG>B9BAHG<?F>FEGH@9CGG3CDH>8?)80???FGEFFDAAFG@=@@4@C=E<BDBBCC;@35;=;@CCCC@<?B<:(,49:4>
@3R7
TATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGG
+
@@CDDDDDHFHAHFBGHHGHGGEFCDAF@FHEHHGGHFGEHBFHIIGIEIHEHDFFFFECECCCAACCCCBBCBBCCCBBBCCCDCBBCBCCBBCCCCC>@
@3R8
TCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGAGAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCA
+
CCCFFFFFHHHHHJJJJIJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJIJJIJJHHHHFFFFFFFEEEEEEEDDDDDBDDDDDDDDDDDD
@3R9
CCACCCCTCAACCCCTGTTTTCCCCTGCCTTCCTTGCAGAGGCCATGGAGGACGAGGAGAGACAGAAGAAGCTGGAGGCCGGCAAAGCCAAGATTGAAGA
+
CCCFFFFDHHHHHJJJJJJIJGIJJIJJGIJJJJJJIJJJJIJJGHJIFIJIIIGHHFFFFDCEEDDDDDCDDDDBDDDDDDDDDDCDDCDDDDCDDDDD
@3RA
TGGCAGTGAAAATGTTGAATGTGACAGCACCTACACCTCAGCAGTTACAAGCCTTCAAAAATGAAGTAGGAGTACTCAGGAAAACACGACATGTGAATATC
+
CC@FFFFFGHHHHIGIJGIJJHGIJJIGIJJJJIJJIJCGHJIGIJJIJJIHIIJCHJJJIGIIIIFGGIIG7@EEHHHGDFFFECCDDBDDDCCEEEEEE
@3RB
CTAGAGGGAAAGCGAGAGGGAGACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGC
+
CCCFFFFFHHHHHJGHHIJJIIGIJJIJJIJJIJJJJJJHHIHEHFDFFDEDBDDDDDDDDDDDDDDDDDDDDDDDDEEDDDDDDDDDDDBDDDDDDDDD
@3RC
TCCAATTCCACAGCCCTTCCGACCAGCAGATGAAGATCATCGAAATCAATTTGGGCAACGAGACCGATCCTCATCAGCTCCCAATGTGCATATAAACACA
+
@@@?DFFDBFHHHHIIIIHHGE@DHIIGHEGIIEHFGG@CEHIIGIIGGIIIIIIIIGIIFHEDDCDBBBCCDCDDDDACDDDCCCCC>CCACCDECDDD
@3RD
CCTCCGTCCAAATCGACCTTTCCTTTCTATCCCCAACCACCCCTCAACCCCTGTTTTCCCCTGCCTTCCTTGCAGAGGCCATGGAGGACGAGGAGAGAC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHHHFFFFEEEEEEDDDDDDDDDDDDDCDDDDDDDDBDDDDD
@3RE
CTCCCACCAAAAGCATAAAACGACCATCACCAGCTGAAAAGTCACATAATTCTTGGGAAAATTCAGATGATAGCCGTAATAAATTGTCGAAAATACCTTC
+
CCCFFFFFHHHHHJJJJJJJJJJJIJJJJJJJJJJJJJJJJIJJIJJJJJJIJJJJJJJJJJJHHHHHHHFFFFFDDDDDEDDEEDDEDDDDDDDDDDDD
@3RF
ATTTTTATGGTGGGACGAGGATACCTGTCTCCAGATCTCAGTAAGGTACGGAGTAACTGTCCAAAAGCCATGAAGAGATTAATGGCAGAGTGCCTCAAAA
+
@@@DDDDDFDFHHIHIE?FHAAFGCDDFGG<BFDHEAGDHGDGHII*BDFGGG;=@DGG=CEEEHEB@BACCC>A@B9@CC@A@:<A?@BCCCC>4+>:>
@3RG
CCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTTATGGGCAGGAGT
+
@@@DDDDDDF8F??EFFIIIB9FC3AFFFAGBFFFIEFBCFGEFFB7CF;BCFFGIGGEE;AEDB>DCCCB@:;?BAA@A@:?@(05??@ABA?@BBB0<+
@3RH
CCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCC
+
???BB2+==ACDD@EDEAEAB?EBBCDB?DD;0B0?DBDDB>8/9DDEBDA8=7@D;=@@C;67:56(6?>>=@=;;555>;AA>58???<?<<4>A>AA?
@3RI
CCTCAGTCCTCACCATGCCTCAGGAGGTCAGGGCAGCCAGAGAGCATCCCACCTGCTCCCTGCTGGAGCAAAAGGCCCCAGCAAACTTCCATATCCTGTTG
+
???DDDDAF>DD?FGEBG@BEG3?<GEHIFFGBFGECHGGI@??@FCFGHHGEGIAFGDGAD;3=>;BD?D>;>?ABBB<7<?CCBC@ACCCC@ADCCC:A
@3RJ
CCTCCCTGAAGAATTCCAACCCCGACGAGATTGAAATCGACTTTGAGACCCTGAAGCCGTCCACACTGCGTGAGCTGGAGCGCTATGTCACCTCCTGTTTG
+
@@@DDFFFGHHHHIEHGGGFGGII@@GFHEIGIIEHIAHFEEGHIIGGIIIHGDEHCBECCCCCCBCCCB8?8@>CCC@B<B9?><@AADCCCBBCC>ACC
@3RK
GCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTC
+
?7?DBDD)A;B??<@>FEHE@CCE?C*?FGHFG7@@@@=;3C==@FH>D4=7CC7==;A5?;;(;3@CCCD:@>5>?(,5(389?@BCBBCCC<4>:A?@
@3RL
CCTCAGTCCTCACCATGCCTCAGGAGGTCAGGGCAGCCAGAGAGCATCCCACCTGCTCCCTGCTGGAGCAAAAGGCCCCAGCAAACTTCCATATCCTG
+
CCCFFFDEGHHHHJGHIIJJJIGI<FH?FHGHGIIJIHGIGGCDGIGHGIIJJJGHJGIGJGEFHHFEFFFEEEDDDDDBDBCCCBCCDDCDDD@CDC
@3RM
ATTTTATTATTTGGGGGGAAAAAAGAGGCCCCTCCCCGGGCCGACACAATTTGTGGGAAGGCTCCTCAAACCCCCCCCAGAGGGGGGGGGTTTTTTTTTCT
+
;07@5))2)2.)2@((('&&(((&0(((+(()(&+(&))&&&)&&)&((((+++(+&+(((((+((((5(+280&&)&&((+2:95563&)&8(28805(4
@3RN
GAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGG
+
@?@DDDFDHHHFHGIJIIJJJIJIGHICHIGGHIJIJJJIIIJIIJHHJIIIJIIIHHHFFCDDDDB?BBDDDC>CDDDDDDDDBDDDDDDDDDDDDDDCD
@3RO
CACAAAGAAAGTTAGAACAACTCCGGGCAGAGCTGGATGAGATGTATGGGCAGCAGATAGTGCAAATGAAACAAGAATTAATAAGACAACACATGGCAC
+
@@CFFFFFGHHFFFHIGIEHGHIIJJJIIGHJEIIIEFHIIIJJHIIIJJIJJIIGGIIIDHHHGHGHFFFFFDECEEDDDDEDDCDDDABDBCDDDDD
@3RP
AAGGAATCATCACTTAGAGCAACTCAACCAAGTGAAAATGATAAACTTCAGAAAGAACTCAATGTACTTAAATCAGAACAGAATGATTTAAGGCTAC
+
@@CFFFFFHGHHFGHHIIGDGHIHEHGGGIIJIIJJJJIGGGIJIIFIIHGGIIJJJFIGGIIIIICGGIGJJGIIIFEHFEHDBBBCFFECCC@C=
@3RQ
CCTGAAGAGGTGGCCCGACGTTGGGGCATTCAGAAAAACAGGCCAGCTATGAACTATGATAAACTTAGCCGTTCACTCCGCTATTACTATGAGAAAGGAAT
+
@CCFDDFFGHADCG@FHIIGCGHIGIIGIIIIIGGIIIIIIIIGGHGFEFHAEBDCCDCBEEECECECCA@BBCCCCC??B<BBCCCCDDACCCCCCCBCC
@3RR
CATCACCCTCATTCGGGGTCTGGGCCATGGCGCCTTTGGGGAGGTGTATGAAGGCCAGGTGTCCGGAATGCCCAACGACCCAAGCCCCCTGCAAGTGGCTG
+
@@@FFDDDFHDBFDHIII:CDCEGIGIIGBHD:GGHIIIII;AE-=@AHEHHDFDDDCC@A>CDBBDBBCCCCCBDB@BDDBBBDBDDDDDDDDD@@C@?B
@3RS
CTCACTTGGATCCAGACATTTAATGTGGATGCACCATGCCAGACCGTGGAAGATTTAACGAATGGGGGTGTGATGGCCCAGGTTCTTCAAAAGATAGATCC
+
1?;=:BBDHHDDCAFBHHIIGDHIIC:2CGFGHGGDIEHIG>B@A?)8@FHCHGGIIIGECHIHGEB'9835:3@:?A<<??@CCC@AAACCA@:A:>A>:
@3RT
TCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGC
+
CCCFFFFFGHHHHJIIJIJIJJIIFGIIIJJJJIGIJDHIJJJIIGHIIJJJHHHGHCDFFFFEEEEDEEDDDDDDB:>ADCCDDB@BACDDDDDDDDDDD
@3RU
GGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTAC
+
C@CFFFFFGHHHHJIJGGGIJJJJJJJJIJGGIGIJIJJGGGGGIJJJJJJIJIIHHHFHFFFFDD=?CCDBDDDCDA?CDDCDCDDDCDDDDDDCDDCDD
@3RV
CGGCAAAGCCAAGCTTGCCCAGTTTCGACAAAGAAAAGCTCAGTCGGATGGGCAGAGTCCTTCCAAGAAGCAGAAAAAAAAGAGAAAAACGTCAAGCAGT
+
@?@?BADDDBDFH?EGIEF?EGCBFHD7CCFGH@GFCEIIGE@?D?@FFGHG;=@E=?EHBBB7?;>@6>9;?CCCCB?>B9<93>>A8<<28<<ACBCC
@3RW
ATTGAAATCGACTTTGAGACCCTGAAGCCGTCCACACTGCGTGAGCTGGAGCGCTATGTCACCTCCTGTTTGCGGAAGAAAAGGAAACCTCAAGCTGAGA
+
BCCFFFFFHHHHHJIFIJJJJJIJJIGIJJHIJIJIIJJJJJJIJJIIIIJJJHHHFCFFFFEEEDEDDDDDDBDBDBDDDDDDDDDDDDDCCCCCDCDC
@3RX
CAGATTGTGCAAAAGAACCAAGAAATAAAAAACATGAAATTAGAGCTGACTAATTCTAAGCAAAAAGAAAGACAGTCTTCTGAAGAAATAAAACAGTTAAT
+
@@<DD?D=CCFHABFCDBBFF;3EFCGHGIGG>HGHIIIEEEGECGGBHGEH<BG>FFGHIAFGHHIHFEE>;;;.;@@@@ACCCCCCCCCCC<?C,;;@@
@3RY
TGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCC
+
B@@FFFDFHHHHFHHJIJIHGHGHIJJIJJJJJIIJHIJJIIJJJJIJJJJJIJIJIJEIJIIJJJJHHHHHDDFFFFEEEBDDDDDDCDDDDCDDDBDD
@3RZ
CTGGAGGAGGGAAAGACAGAAAAATAATTCTGTGGGATCATGATCTGAATCCTGAAAGAGAAATAGAGGTTCCTGATCAGTATGGCACAATCAGAGCTGT
+
BBCFDFFDHGHHHIJJJJJIJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJIJJJIIGIJJJJHHHEHFFFFFFEEEEEEEDDDDDDCCDDDDDDDD
@3S0
TACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCAATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTT
+
;=11<>;@<@A<CACA3<<+,<=A7A0+:*):?AAB7<A3:)997=?4=/=*)).).7A))8;>5).;A7.(7;53>9(.(.6;>=;95=95876&08+3
@3S1
AGGGCTTCTCTGTGGAACTGGAAAGTGAAATTTCAACCACAGCAGATGACTGCAGTTCAGAGGTAAATGGTTGCAGTTTTGTGATGAGAACAGGAAAGCCT
+
CCCFFFFFHHHHHJJJJJJJJJJJIHHIJJJJJJJJJJJJJJJJIJJJIJJJJJJIIGJJHHJFHIIIIJDHIHHHFHHHEBEEFDEEEECDDDDDDDDDD
@3S2
AACAAGCTCCCCGGCGAGAAGCTGGGCCGCGTGGTGGACATCATCCAGTCACGGGAGCCCTCCCTGAAGAATTCCAACCCCGACGAGATTGAAATCGACTT
+
:??D1++22A7D6EE1C@:0909?@@DDA/@-49(5(...-;>>>9(5,:::;6=570829<?7>A<A:39A>(>:33&55;-5;3;><>A3>AA>7258>
@3S3
CTCAGTGCTGGCAACATCAGCCTGAAGACAGGCCCAACTTTGCCATCATTTTGGAGAGGATTGAATACTGCACCCAGGACCCGGATGTAATCAACACCGCT
+
@@<?D?DDHGDHDHHGGIGAEGHIIIGGGIIIIEDGGEGGIG@>DFHD@GBFHIGGIII@ADGEHCHEHHFHFFFFCC?=ABBB;@B>@BDDACCCBBBBB
@3S4
CAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCT
+
CCCFFFFFGHGHHJJIJIJIJJJJIJHHIJJIIJJJJJJJJJJJJJJJJJJJJJJGGHGHHHFFFFFFEEEDDDDDD;CCDDDDDDCCCCCDDDCDDCDC
@3S5
GCCCAGCCCACTCAAGGATAGGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTC
+
==7?=AA;<AA3@ABB@BBB+<+?=@3=ABBBAAABABB:AA?4>>>A;ABAA>ABBBBBBB<AAAA>9>@@@@,;;;???>;=??>??;==???9;=<=
@3S6
TTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTG
+
?@@DDDDBD;BD>GEHEHCFDC2<E4BFHGCEHID9DCFDCEGGGFAAFCC7@4CCHFAHD;?CEC3;>@8;>:<9ACCCB553>AC@@ADDA@A@BBBCC
@3S7
CACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJIJJJIJJJJJJIJJJJJJJJJIHHHHHHFFFFFEDEEEDDDDDDDDDDDDDDDD
@3S8
ATGAAATGGAACAAGATAAAAAAGTAGAAAACTCAAATAAAGAAGAAATACAGGAAAAGGAGACAATCATTGAAGAATTAAACACAAAAATAATAGAAGA
+
CCCFFFFFHHHHHJJJJJJJJJJICFHIJJJJJJJJJJJJJJJJJJJJIJJJIJJJJIJIIGHIJHHHHHHFFFFFFEEEEDEEDDDDDDDDDEEDDDDD
@3S9
CTTCAAGAAAAATTTGCACAACTTGAAGCAGAGAATAGCATTCTTAAAGATGAAAAGAAAACCCTTGAAGACATGTTGAAAATACATACTCCTGTTAGCC
+
CCCFFFFFHHHHHJIJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJIIIIJJJJJJJJJJJJJJIJJJJJHHHGHGFFFFFFEEEFEDEDDDDDDDDD
@3SA
CAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGG
+
@@@FD?BDFHFDDGEGGGGGHGIGHIDEGHGHHIGHGHHEIJDGGIEIJGGGCHIG<EECEEEAECDEFF?C;ACACEEDDDDDDB@CCCDDDDAD?CCBD
@3SB
CAGATGGAGTACAGGGACTTCAGACATTAACCATGACAAATTCAGGCAGTACTCAGCAAGGTACAACTATTCTTCAGTATGCACAGACCTCTGATGGAC
+
@@@DDDDAH=CFDHE?FGFFHIIEIIIIIIIIHIGHIIICHHGIIGIIIHIIHIGBDGHGICGGGGHIHGIIIHEEGHHHHFFEB?CECEACCCDCCCC
@3SC
CGACTTTGAGACCCTGAAGCCGTCCACACTGCGTGAGCTGGAGCGCTATGTCACCTCCTGTTTGCGGAAGAAAAGGAAACCTCAAGCTGAGAAAGTTGATG
+
@C@FFFFFGHGHHJJIJJIJJJIIJIIJJJJJJIJIJJJJJJIJJJJIJJIJIHHHHHFFDFFEEDDDDDDDDDDDDDDDDDDDDDDDDCDDDDDCCDDDD
@3SD
CAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCC
+
CCCFFFFFHHHHGGIJJJJJJJJJJJJJJJJJJIJJIJJJJJJGHIIGIJJJJJJJJJJHHHHHHFEFFEEDDDDDDDDDDDEDEDDCDDACCCDDDDDDD
@3SE
GCCACATGGGACAACCGGGGAAGGAGGTCCTGTGGCCACTCTATCCAAGCCTTCCCTAGGTGACCGCTCCAAAATTTCCAAGGACGTTTATGAGAACTTCC
+
?7?DDDDBH<DHFIBHHIII<??GHIIBBAF@GDE?EH7FFIIIDHIEEHHF=77@DECCC;;;;;??B@CCCBCCCADDCCBB<<>BC?CC@CCCCCCCC
@3SF
CCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGGGTTTATGGGCAGGAGC
+
7>12+?3+22++22<2A>3,<?7<7C7+2211111?5?410?<A84A8ABBBBB4A778AA<45;555.6,,,,8,,,:(,,(9(0)&2;8(329()5(((
@3SG
GTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAAC
+
CCCFFFFFHHHHHJJJJJIJJJJJJJJIJJJJIJJJJJJJJJJJJJIJJIJJJJJJJJJJJJJHHFHHFFFFFFDEEDDDDDDDDDDEDEEDEDDDDDD
@3SH
CTGGATCATTTGGAACAGTCTACAAGGGAAAGTGGCATGGTGATGTGGCAGTGAAAATGTTGAATGTGACAGCACCTACACCTCAGCAGTTACAAGCCTTC
+
CCCFFFFFHHHHHJJJJJJJJIJJJJJJJJJJHHIJJJJJBFEGGGHJHIJHGHIJJGIFHGGGGIFHIFIJIJHHHHHFFFFEEEEDECDDDDDAABDDD
@3SI
CTGAAAATGAGTTTTCTTTAAGGCCAATTGACAGCAACACGTTTGAAATGAATGGCAAAGCTCTCCTGCTGCTGACCAAAGAGGACTTTCGCTATCGATCT
+
@?@DDDBDFFF4DFGFIIEEHC+?CF?+<3CAHFDDEI?D@BDFBGE@BFFFE<@?FFC@F@FAFFE@EFFI>??;?DD?;@>;@@BBA@@BBBBBB<?B@
@3SJ
GGAAAACAAGACGAATAAGGGCAGCAGCAGGAGGAGGAAGTGAGGTATCCAGATCCAGGTCTCCTGAGCTACATCAATGAGCTGTGTTCGCAGAAGGACTT
+
<<<???77=?1)(((((.):=;????(6((3(<;914-=<))))..)3<..8).8=3=3:=1=9);38;=19=(6;9-3-(532,,,3,('&)855((+(+
@3SK
CACCGCTCCAGGTCACCTATCACGACAAATCACCGGCCTTCTCCTGACCCCGAGCAGCGGCCCCTCCGGTCCCCCCTGGACAACATGATCCGCCGCCTCTC
+
@@@DFFFFHGGHCGDGIJGJIJIIHJIIHJJGIIGGIJIIGIIIIJIIGJJHGFFDECDDDDDDBBD7;BBDDDDDDDDBDDDDDDDDDCDDDDDDD>BCD
@3SL
CAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGG
+
@@@BDDDDDFHHDBEIBHEG;@D@GIGGCFDBFHIIIIBFFGAH?D=DEEGCGAC>FGDHIIGFE3;?B@B6@CCEA>A;AC@C?<(>ACDDD22<>>>BB
@3SM
GGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAAT
+
?<@D;DDD>FD+AEEEEFFFFICHEFIC3FCFBGFFCEDGFIEIIAFFFEIIIIIABF@AFIGIFF=CBDDDD<BB@9AABBBBBB?@BBAB@(+4@A:B
@3SN
ATTGGACCTTACTATGAAAACCATGGATACCAACCGGAAAACCCCTATCCCGCACAGCCCACTGTGGTCCCCACTGTCTACGAGGTGCATCCGGCTCAGT
+
?@<1BDDDD8AFDDE?4A:+CE;<C9<2AEGEAEACFG:FFGICF@FBAAA5@EAAEDD;@C6..5;;35;??B@@:AB5><<<>)8>:@BA@<@.5@?:
@3SO
AGTGCCTGTACAATGTCAGTGCCTATGATCAGAAGCCACAAGTGGGAATGAGGCCCTCCAACCCCCCCACACCATCCAGCACGCCAGTGTCCCCACTGCAT
+
8??D??B;AD4ADA<<<A@,ADE<EF<AAEE+AC?EEEECDD*?9?DE;D*0001BDCCBC>@AAA?</,;58?AA<AAA??-&89?+:4>A>2<;<:>:3
@3SP
GGAAAATCAAAATAAAACTCTAATAGAAGAGTTAAAAACTTTGAAGGATCTTTATTCCAATAAAAGTGTTTGATTCCTAAGAAAGAAAATATTTTTGTGG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJHIJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJIBFHIIJJJJJIJJJJHHHHHFFFFFFEFEEDDDD
@3SQ
AAAGAGATGAGAGACCACTCTTTCCCCAAATTCTCGCCTCTACTGAGCTGCTGGCCCGCTCATTGCCAAAAATTCACCGCAGTGCATCAGAACCCTCCTTG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJIJJJHIJJJJJJJJJJJIIJJJJJJJJJJHHHFFFFFFEEDDDDDDDDDDDDBDDDEDDDDDDDDDDDDDD
@3SR
CTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAAC
+
CCCFFFFFHHHHHJJJJJIIJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJIJJJJJHHHFDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDCDDD
@3SS
TGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTAT
+
@@@FDEFFHHADHGIGEBGGFHDHIEHIEHGABHH?99B@GCGIGIIGIICHCEHIHHCHEBD@DCEA@CEAB?C;ACC@C?ADDBDA@44:+:@C>@C>
@3ST
CGAAGAAGAGCTTTCCAAACTGAAGGAAGATTTAGAAATTGAACATCGAATAAATATTGAAAAACTTAAAGATAATTTAGGCATTCACTATAAACAGC
+
C@@FFDEFFHDHHJEFDGIIIIHHJIIIJIIHJJIJJJJIJJJGJJEG@HGIIIGGIGIGJIJJJJIJJGH@GGDHHHHDHFFFFFEEEDEDEEDCDD
@3SU
ATTTGTTTGAATTCAGATGACATTATGCCAGTTGATTTAATGGAAACGAAGAACCGAGAAGGGTTAAACTATATGGTACTTGCTACAGAATGTGGCCAAGG
+
;?@A?DBDFFBCFB?EC?<AHF<A4FB<F+CA<A11:?E9?9DD@D@DEGFEG?8?7@F8C@A=@E=77.7;7?))7(6@;A;>ABAA;5>>B>:?@B@BB
@3SV
TGCTCCGTGTCGATCATCTACAACCTTAACAATGAACAAGATATTCGAAAAATATGGGGACCACTCAAAACCATACCTCTCACTTCAACCTCCCTCACCAT
+
30;(2)(.(.2(2=?;8>))..82())1.)@).2).).:=3?1=63=??55...))).(-;(;().8.);36(:66=1(7;<>1-5(:2,;(;603((+:<
@3SW
CTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTT
+
CCCFFFFFHHHHHJJJICHGHIJJIHIIJIJIJJFDDGIJJGIIHIJIJIJJJIIJIJIJJEIJJJJHHHHFFFFDEDEEEEDDDDDDDDDDDDDDDDCCD
@3SX
CATGGTCCTTTGGAGTGCTGCTATGGGAAATCTTTTCTCTTGGATATATGCCATACCCCAGCAAAAGCAACCAGGAAGTTCTGGAGTTTGTCACCAGTGG
+
@?@BAB>DDDDHFF@:CF@HHIFHGGGEHIEIICD?G@GFDFDG@FAGGG9BGFBHHGGCBBGGCG@;CGECHFHHEECC>ADC(>;@CC=;>;@A9@:?
@3SY
ACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGT
+
@CCFFFFDHGHHHGGIIGHGJGIGFHIJGJIGIIHJGIIJJJIIGGGGJJJJJIIJIJJIJJFCEHHFFFFFFCABDDDDDDDDDDDDDC@CCDCCDD>@B
@3SZ
GTAAGGTACGGAGTAACTGTCCAAAAGCCATGAAGATATTAATGGCAGAGTGCCTCAAAAAGAAAAGAGATGAGAGACCACTCTTTCCCCAAGAGAATTTG
+
@@@FFFDEHHFHHIJJJJJFHIIIGGHIIIJJJIJCDGIJJJJJJIJJII8DGIJIJJJIIHJJJIIDEEHHHFFEFCCEDEDDDDDDDDDDBDDDDDDCD
@3T0
CCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGT
+
CCCFFFFFHHGHHIIJJJIJIIJJJJICHIJJJJJJJJJIJIJIJGGGGIJJHHHHHHFFFFEFEEEEEDDDD>CCDDDDDDDDDDDDDD?ACCDDDDDAC
@3T1
CTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTC
+
CCCFFFFFGGHHHJJGIJJJJJJJHJIJJJJJGIJJJJJJIJJJJJJIIIJJJJJJJIJJJIJJJJJHHHFFFEDEEEDDDDDDDDCCDDDDDDDDDDDCD
@3T2
GATCCGAACTACACCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATGACATCTCCTGTGACTCTCACCTCTCAGACAACTAAGACAGATGACCCCCAAT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJIIIHIIJJJIIIIJJIJJJJJJJJIIJJJJHHHHGDFFFDEEEEEDDDCCDDCDDDDDDD
@3T3
CCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGT
+
@@@DDDA?FBFHBBBEHEGE?DFHHCHGCHCFH?B@CB=>8CDH>@;@D@G3=.7A?ADCC;A?@6>@ACC=5(5(5;ABB2?;?CC?B<?C?C:+48<8:
@3T4
GTTCCTCCTCTCCTGGTCTCTCAACAGGCAAAACGGGAGGAGGAGCGCAGCCCAGCTGCCCCACCACCTCTGCCTACCACCTCCTCTGGCAAGGCTGCAA
+
1:=DDDDDFFA?FFEA<AAFAFHII<ACAGF8?:))?D:DGI0B1=/;A4-6?(.67;6>@?=@B??@BB>A:AB@<?B:88???3>:::@><<@B?B(:
@3T5
ACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGT
+
@@@DDBDDDDDFHGIIGGGGEHGGGHIIIIIIIIIGGDEHIIIGGGICHHIGIHIGIIIEFDHFDD?BBCDDABDDBDDDDDBDCDD@CCDDCDCDDDCD
@3T6
AAAAGAAAAGCACAAAAGGAAAGAGGAAGTGGAAGAGAATAAAAAAAGCAAAGCCAAGGAACCTCCTCCTAAAAAGACGAAGAAAAATAATAGCAGCAAC
+
@CCFFFFFHHHHHJIJJIJIJIJGIJGIGCDHGJJJJJJJJJJJJJIJJJJJIJIHHGEFFFFEEDEDCDDDDDDDDDDDDDDDDD<?A@ACCDDDDDDD
@3T7
TATTAATGGAAAGACTCAATCAATCTGATTCTATAGAAGACCCTAACAGTCCAGCAGGAAGAAGGCATTTGCAGCTCCAGACTCAATTAGAACAGCTCCA
+
CCCFFFFFHDFAHIGIHEFIGBEAHHIGIIIIIIIGHGDGICIIHIIGIEGHIII@HIGEHGHGGEHGIEIGHGHHHHCFDFFFEEEEEC;A@CCB@>CC
@3T8
CCTTTCTATCCCCAACCACCCCTCAACCCCTGTTTTCCCCTGCCTTCCTTGCAGAGGCCATGGAGGACGAGGAGAGACAGAAGAAGCTGGAGGCCGGCAA
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJIIJJJJJJJJJJJJJJJJJJIIIJJJJJHHHHHFFFFDBBDDDBDDDDDDDDDCDCDDDBDDDDDDDDD
@3T9
GTCACATCAACGAGGAGGACACAGTGCCTCTTTCTCACTTTGATGAGAGCATGGCCTACATGCCGGAAGGGGGCTGCTGCAACCCCCACCCCTACAACGA
+
@B@FFFFFHHFHGGIJIJGIJGIJFHGIJGGIIJIIJGIJJIFHIGHGGIIIGIIIIIGIJIIIIHFDFDDBDDBBDDDDDDDDDDDBDDDDB??CCC@B
@3TA
CTTCATGAAGACCTCACAGTAAAAATAGGTGATTTTGGTCTAGCTACAGTGAAATCTCGATGGAGTGGGTCCCATCAGTTTGAACAGTTGTCTGGATCCAT
+
@@@FFEDAHHFHHIHIJIIIGIJJIIIIGEEGHGIIJJ@FHHIJIHGHIHCGIIHIBFCDDFB=B==FCGGIEEEEEEDEFBB@CACC>@CCCDCCCDDCC
@3TB
ATGAGGCCCTCCAACCCCCCCACACCATCCAGCACGCCAGTGTCCCCACTGCATCATGCATCTCCAAACTCAACTCATACACCGAAACCTGACCGGGCCTT
+
CC@FFFFFHHHHHJJIIJJJJJJJJJIJJJJIJJJBGIJHEHCEFFFFDCEEEEDDDDDDEDDDDDDDDDDCDDCDDDDDDDDDBDDDDCDDDDDDDBDDC
@3TC
CCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATGACATCTCCTGTGACTCTCACCTCTCAGACAACTAAGACAGATGACCCCCAATTGAAAAGAGAAAT
+
@@@@DDDDHFFFHI>DEHH?FAGII;EFF??1?<EFHGG@DFFGI>GH<FHGGG@FHG?FH<FHBEHI>DADAEGEHEH=>@BDBC@C@>@CCAC59<AC>
@3TD
TCCACAAATTCGAGCATCACCTTCTCCCCAGCCCTCTTCACAACCTCTCCAAATACACAGACAAACTCCAGAAAGCAAGAATGCTACTCCCACCAAAAGC
+
@@CFFFFFHHGHGIGIIJJIGFGHJJJIIJJIJGJJJGHJIJIJJIIIIIJJGIJJJIIIJJJJJHHHHHFFFFFDEEEECDADDDDDDDDDDDDDBBDB
@3TE
CCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJIIIJJJJJJJJJIJJJJJJJHHHHHHFFFFFEEEDEDDCDDDDDDDDDDDDDDD
@3TF
GAAGAATCAAAAATAATGGTGGAAGATAAAGTTTCTTTTGAAAATATGACTGTTGGAGAAGAAAGTAAGCAAGAACAGTTGATTTTGGATCACTTACCATC
+
@@?DBDDDHDD?F:A?B9<<3<C>CB???BBBBBFFC@F>@GEF@4?B*9*?90?FE9BG9BBC3)/=;)==@77==??3A;);?D@C>>A;3;:53;A>(
@3TG
CCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGA
+
@@@FADFDHFHHHEGEIJGIIJGGJHGGGIIJGIJJJJ@GIGFHHIIGGCFGHJJFIGHJIIJGECEEHHFF;;BDECCCCDBB@BDDDDEDCCDE@DC@
@3TH
GTTCCACAGACCAGGAGAAGATTGAATTCCTGAAGGAGGCACATCTGATGAGCAAATTTAATCATCCCAACATTCTGAAGCAGCTTGGGGTTTGTCTGCTG
+
@@@DDAB?C;FF?@7;++<ACHH<A<2C9C>E?G@DF8@==F30BBD*/9B388=CFI>;;@@CFF==;>AEAE=;37;3;@>@C>BB(9,8?B9:@3:@:
@3TI
CCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTAT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJIJFHJJJJJJJJJJJJJJJHHHFFFFFEEEEEDDDEDDDDDDDDDDDDDDDDDDEDDCDDDDDDDDDDD
@3TJ
GCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGT
+
@@@DDEFFHDHDFGEEHBH8AGGE@?GICHIECFHGEBHCFBFHCHGHIIHGHIGIHICHCG@>E>GCEEBBAB?CDACAC>:ACBDDDCBA@ACCECCC(
@3TK
TTCCCTTGGACAGTGGCCCCTACAGCCCGTTTGGGGGGCAGAGCAACGGAACTGCGGGAGATGCCGTGGCACCGCGCAGGCCGAGACGGGCCTTGGGTACG
+
0(78(.)64)2.5<)<(((36((.<).8((()(-(-<0&61-223((&)22&+((&&&&)&((++&)0)0((())&)0&&&()5)&)()00&+2(86(((&
@3TL
CAGGAGTCCTACCCTCTGTCAGTGTCTCCCATGGAGAATAATCACTGCCCAGCGTCCTCCGAGTCCCACCCGAAGCCATCCAGCCCCCGGCAGGAGAGCAC
+
CCCFFFFFHHHHHJJJJJJGJJHHJJJJJJJJJJJJIGJJJJJJJJJJJJJJGJIJJJJIJJIIHHHHHFFCDDDDDDDDDCCDDDDDDDDDDDDDADDDD
@3TM
CTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACC
+
@@@FFFBDHHHHGGHIGGIGGIEHHJIJJIJIJJBFHHIJDBFGHIGIJHEIIJIJIGHHHHFFDB;ACCECBBBDDCCBCC<CB>CCCDCC@CDDCDCDD
@3TN
GTCAAAGTCAAGACAGAAGGGGGGTCAGCTGAGCCCTCTCAAACTCAGAACTTTATCCTTACTCAGACTGCCCTCAATTCGACTGCCCCGGGCACTCCCTG
+
@@CFFFFFHGHHHJJJJJJJJJJD9BBDDDDDDDDDDDDDDDDDDDDDCDDDDDDDDDEDDDDDDDDDDDDDDDDDDDEDDEDDDDDDDDCDDDDDDDDDD
@3TO
ATGTATGGGCAGCAGATAGTGCAAATGAAACAAGAATTAATAAGACAACACATGGCACAGATGGAGGAAATGAAAACACGGCATAAGGGAGAAATGGAGA
+
++:4=4:+A;;1+ABAAE:<A4AFDA>A<@CBECCDEECDEDEED9?D807;?9BCEC)8)=AC9AD1=CDDA=;?A@6=@>?3>AAA9533<9>:>A?9
@3TP
TGTAGAGCTAATGTTTACCTTCTTCCGACCGGGGAAATAGTTTATTTCATTGCATCAGTAGTAGTACTATTTAATTATGAGGAGAGAACTCAGCGACACT
+
@;?DDFFDDHHHGHGBHDHHHIEHD?FEDBAH>HGGGCGGCHC@FHGGGICHIIHFFECEEAEC?CBE@@C>CCCEDDC@CDDDD18?CCA>>459@>BC
@3TQ
GTGACTATGACAAGCAGGGGTGCTGAAGGATCAGTTTCTAAAGTAAATAAAAGTTTTGGTGAAGAATCAAAAATAATGGTGGAAGATAAAGTTTCTTTTG
+
@@CFFFDFHAHFHJGIIIIICFGHIJGIIGIIJIGIIIEIJIIFHIJIJJJIJFHIGIJ6CDGEGGHHGFHHFFFEFEE;@CACC=CACCD@CCDDDDDD
@3TR
CTGATTGAGCCTGAAGAGGTGGCCCGACGTTGGGGCATTCAGAAAAACAGGCCAGCTATGAACTATGATAAACTTAGCCGTTCACTCCGCTATTACTATG
+
CCCFFFFFHGHHHJJJIJJGHIIIJJJIIJIJJJJIGIJJIJJJJJJJJIHHHFFFFFCECEEEDDDDEEDDDDDDDDDDDDDDDDDDDDBDDDEDDDDD
@3TS
GCCTGCAGTCAAGAACAGCCCTTTAAATTCAGCTATGGAGAAAAGTGCCTGTACAATGTCAGTGCCTATGATCAGAAGCCACAAGTGGGAATGAGGCCCTC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJIIIJJJGIIJJJJJJJJFGIJJJJJJJIIJJIHHHHHFFF?CEDDEDDDDDDDDDD
@3TT
CTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCC
+
CCCFFFFFHHHHHJJJIJJJJJJJJJJIIJIJIJJJJJJJJJJJJJIJJJJJJJJHIJJHHHHHHFFFFFEEEEDDDDDDDDDDDDDDDDBDDDDDDDD
@3TU
GGAGAAAATTCTGGAGTTTCTGCTGCTGTCACTTCTATGTCTGTTCCAACTCCCATCTTTCAGACTAGCAGCGGACAGTACATTGCCATTGCCCCAAATGG
+
@@@FFFFFHHHHHIJJHIJJJJJJJJJIJJJJJJJJGIJIJJJIJJJJJGHIIIJJIIJJJJJJJJJJIJJIIJHFFDEEEEFEDDDDDDDDDDDDDDCCC
@3TV
CAGTAAGGTACGGAGTAACTGTCCAAAAGCCATGAAGAGATTAATGGCAGAGTGCCTCAAAAAGAAAAGAGATGAGAGACCACTCTTTCCCCAAATTCTCG
+
CCCFFFFFDFHHHIJHHIIJJIJIJJJJIJJJJJJJJJJJJJJJJJJJJJIJFHIJJJJJJJJJJJJHHFHFFFFFFCDEDDDDDDDDDDDDDDDDDDEDD
@3TW
CAGGGCCCATGGGCCAGATGCAATGATCCTTGTGGATGGACAGCCACGCCAGGCCAAGGGTGAGCTGGGGCTCTCCCAAATGCTCCACATTGCCAGTC
+
CCCFFFFFHGHHHIJGIJJJJJJIJGHIJIJIGHIIIIGGGJIIGGGIIJGGJIDIJIHH=B?DEFEEDDDDDCDDDDDDDDCDDDDCDDDDDDDDDD
@3TX
GACATCTCCTGTGACTCTCACCTCTCAGACAACTAAGACAGATGACCCCCAATTGAAAAGAGAAATAAGGTTAATGAAAAACAGAGAAGCTGCTCGAGAGT
+
CCCFFFFFHHHHHJJJJJJJIJJJJJJJJJJJJJJJIGGIIIEHGIJJJJJIIIIIJJIGFGGHGIIIHHHFHHBDFFFFD<BCAACCDDDDDCDB?BBB:
@3TY
TTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGC
+
@C@FFFFFHGHHFIIGIJIJGHHIIBGHIIHHGHHHIGEGIGIJJJJJFJIGIJCHIJIIIJJHHHHHFFF;BFECEEEDDDDDDDDBDDDDDDBDBDDD?
@3TZ
GCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGT
+
CCCFFFFFHHHHHJJJHIJJJJJJIFIIJJJJIIJJJJJJJJJIJJJJJIFJJJJJJJJJJIIJGIIIHHHFFDEDEDDDDDDDDCDDDDDDDBDDDDDDA
@3U0
CTAGAAGGTCAAGTAGAATCTTATAAAAAGAAGCTAGAAGACCTTGGTGATTTAAGGCGGCAGGTTAAACTCTTAGAAGAGAAGAATACCATGTATATGC
+
@@@FFEADBFBDFEHGDFFHIHFGHEIHAFAFE@FEHIFCBGGCGGICHEB?FH@GHHGGHBDC@CECECD@CDAC@CC>A9A?C?CCCC:AC>:B>CCC
@3U1
TGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGG
+
@B@FFFFFHHHHHJJJIJJJIJJJJIJJJJFGHIJJJJJFHIIJJJJHIJJIJJJJJJJJJHGHHFFFFDEEEEDDEEDDDCDDDDDDDDDDD
@3U2
GAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGAC
+
CCCFFFFFGHHHHJJJJJJJJJJJJIIJIJJJIJIIJGIIJJIIJJIGHIGIFHGFFFFCCEBEEEDCCCDDDDDDDDDDDDDDDDDDCDDDDDDEDCDDD
@3U3
CATCTGTCGAAATGCACCATGAAGCTTTGAGTGAAGCTCTTCCTGGGGACAATGTGGGCTTCAATGTCAAGAATGTGTCTGTCAACGATGTTCGCCGTGGC
+
1=84====ADDC?E<EB3AA+CFE<A9CEE11:CE4*?**1**0:B6)BDDB9<888'1@;AA7..=AA))).))...;;@(63((,(((,(((''')&&&
@3U4
CTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGAC
+
CCCFFFFFHHHHHJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHHHHFFFFDD=BDDDDDDDDDDDDDDDDDDDDDDDDDDD
@3U5
ATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCC
+
??8BB;BDDB+2C<<<EEIBF?CFI@?8FE3:?CE91?91?*B6:0?@@??@C8B==78../87A=C@DAD>A))?7;A@6>AA>AA????>:;55>(,5<
@3U6
CTCCGGTCCCCCCTGGACAACATGATCCGCCGCCTCTCCCCGGCTGAGAGAGCTCAGGGACCCAGGCCGCACCAGGAGAACAACCACCAGGAGTCCTACCC
+
CCCFFFFFHHHHHJIJIJJJJJJIJJJJJJJGIJJJJJJJHHFFDDDDDDDDDDDDDDDDDDDDDDDDDDDDDBDDDDDDDDDDDDDDDDDDDACDDDDDD
@3U7
CAGATTTCGCCGCCAGCTTTCTGAACCCTGTAACTCCTTTCCTCCTTTGCCGACGATGCCAAGGGAAGGACGTCCTATGTACCAACGCCAGATGTCTGAGC
+
CCCFFFFFHHHHHJGIIJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJIJJJIIHFFFDEEEDDDDDDDBDDDDDDDDDDEEDDDDDDDDDDDDEDEDDDD
@3U8
CAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTT
+
BCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJHHHHHHFFFFFEEEEEDDDDDDDDDBDDDDDDDDDDDDE
@3U9
CGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCG
+
@@@FDDADDADHFGGGGGIIGCGIIIICC=@@FGGII@FF4@AECEEEDEFFEC;@CCCCCC>ACDDB@@C>C?59-9>BB<A@B?BDD>+::CCACCDDD
@3UA
CAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTTATGGGCAGGAGTC
+
@@@BDDDBDHAC<E:CC?AICF>GIGHBAFFDABFGG9FGEEIGGGGB8B8B4@F@F;FB;=BB>?BACC?B;?A>@ACDC@<>@B<?C:@C?89>>@8+3
@3UB
TGATGACTGGACAGTTACCTTATTCAAACATCAACAACAGGGACCAGATAATTTTTATGGTGGGACGAGGATACCTGTCTCCAGATCTCAGTAAGGTACGG
+
@@@ADDDE<?FDBGIBFHHICHHCHHIGI3CFHAGGG=?88D6BBF8@9B?FH@?BD>CCF@;A@GE/?<>C:AC3@;(;;;::(>3>@CCAC>:A(::>B
@3UC
CACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGT
+
@1;?DDDD>?8DAC@E?18?E8CFE@GDF?GF;?09B8???D8.8<CBD>CFCDCCECDEEAE?;49,39>:>AB<28?@?BBB<:9>:@AAAABB>??A:
@3UD
CAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCC
+
CCCFFFFDFFHHHJJJIJJJJJJJJJIJIJJJJJJJJJJIBFHIJJJJJIIJJJJHHHFF?DFFDEEDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDD
@3UE
TTCCAGTTAAATGGATGGCAATTGAATCCCTTTTTGATCATATCTACACCACGCAAAGGGATGTATGGTCTTTTGGTGTCCTGCTGTGGGAGATCGTGACC
+
@@;DDDD?FDFFFI<<CC:3F;:A?<C4+++2:?:C):*9?F<??**:9DB)??6AFF3;(.5.@EEF.==ECBDBDCC;.6(;AB@55;98'5:9(8A24
@3UF
GGCCCAGCGTGGAAAGCGAAGGCGCTTTTTGATCCTTCGTTGTCGCCTCTTCCTATCATGGTGAAGCGGAAGTCAGAGAGCGTTGGCTTGTTTTCCCAGT
+
0(((((2(02((-)2()3((1((:(33()<;;8)))9)(.)85)-((-'.).))).);(((..(-9:3'','((((((+(8)&+52(32&(+(++(2((+
@3UG
GGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGT
+
CCCFFFFFHHHHHJJJJJIJJJJJJJJJJJJJIJJJJJJJJJJJJJJGHJJJJJHHHFFFFDEDEDDDDDDDDDDCDDDDCCDDEDDDDDDDEDDDDDDD>
@3UH
CAAATTCAGGCAGTACTCAGCAAGGTACAACTATTCTTCAGTATGCACAGACCTCTGATGGACAGCAGATACTTGTGCCCAGCAATCAGGTGGTCGTACA
+
@@@DDDDD??FFD<AD@FHG@FIII+<CHHIG<@GFCGGGH?FGH@@GGFDDHIGIICGHIGHIEFGGIIEHGGA@ECHHHDDCCB@CCC;A=@CB@BBB
@3UI
CGCAGAAAGAAGAAAGAATATGTGAAATGCCTGGAAAACCGAGTTGCAGTCCTGGAAAATCAAAATAAAACTCTAATAGAAGAGTTAAAAACTTTGAAGG
+
CCCFFFFFHGHHHIJJJIJJJJFJIJJJJJJJJJJJJJJJJJJGGIJJJFHJIJJJJJIJJIJJJIHHHHHHFFFFFFFDEEDECDDEDDDDDDDDDDDD
@3UJ
GTAGAGAGCTAGAAATCATTATTAACCACAACAGGGCAGAAAATGTACAGTCATGTGATACTCAAGTAAGCTCTTTATTAGATGGAGTTGTGACTATGAC
+
:1:<7?2??@A8A<ABB<C<C<,3,?7<CA<1)@?5?<45?B>=A=AA<A9<*=?98=>>>=A>B38ABABBBA>A3=ABB>;>>);.6;>;;;(-;;5-
@3UK
AAAGCTTTGAAGGTGAAGATGGCGATGTGATTTGTTTGAAATCAGATGACATTATGCCAGTTGCTTTAATGGAAACGAAGAACCGAGAAGGGTTAAACTAT
+
CCCFFFFFHHHHHAFHIIIJIJJJJJJGIIJJJIHIIJJJ*:DGIIFIJJJJIJIJJJJJIJJJJJJJIIJJJJHHHHFFFEEDDBDDDDDDBDDDDDDDD
@3UL
AGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAAC
+
CCCFFFFFFFHFHIJIJJJJIJIIJJIJJJJJIIGIJJJGGIIJJJJIJJJJIIIJJJGGIJJJJHHHHHHFFFFFFEEDEDCDDDDDDDBCDCCDDDDDD
@3UM
GGGAGACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTT
+
?<???D?:@D?DCF=A<EF1E*?@CFDCB1(/B/((75@C@)7@A8=<4;.==<BBBA;:;@>B>A>@@@@BB?<@:?A9@300&)(8<-<?83(:++4>B
@3UN
CCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATG
+
<8=ADD;AD>BD:2CEI<+<<AF@<A<CDE>E<C:4:1:DFD9DDD?9*09BB;B9C<C;44;<:5;;.6)...;;A;>8>?6,(59<<<;?8<>>A>AAA
@3UO
GCTGTATGTTTGAAAAGGGCCCCAGGCAGTTTTATGATGACACCTGTGTTGTCCCAGAAAAATTCGATGGAGACATCAAACAAGAGCCAGGAATGTATCGG
+
@@BFDDDFHHHHHJIIIIJJJIIJJGIIHHIIJJIGGIGIHJIICHBFHGICEHJJIHHJGGIJGEAEHGA@?DFDEEEECBDCCBCBCDDBDCD@CCDDD
@3UP
GCTACTTCTCTGCCACAAACTGTGGTGATGACATCTCCTGTGACTCTCACCTCTCAGACAACTAAGACAGATGACCCCCAATTGAAAAGAGAAATAAGGTT
+
+1=D?A:DBB=<:EE@?:??<<FC3+<22<CGF<C9C::1111?:DFFI@8?F<*B/9B;=FCFD7C@=.@===>=AED>1;A66;AB>BB=A>:::AB55
@3UQ
CTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCT
+
CCCFFFFFHHHGHJJJJJJJJJJJJJJJJGIIJJJJJJJIJIJJJIIJJJJJJJIJJIJJJJJJJJJHHHHHFFDDDDDDEEEDDEDEDCDDDDDDDDDDD
@3UR
CCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGT
+
@C@FFFFFHFHBDHGEIGIJ?GFHIEGHEBDGGHGGGHIIJFCGHGIGIGHGFHEHHEFDDFFFCECEEDDBD>ACDDDDB@BBBCCDDDDCDCDDDDDD>
@3US
GCTGGGCCGCGTGGTGCACATCATCCAGTCACGGGAGCCCTCCCTGAAGAATTCCAACCCCGACGAGATTGAAATCGACTTTGAGACCCTGAAGCCGTC
+
CCCFFFFFHHHHHJHIIJJJJJJJJJJJIJJJJJJJJJJJJJHHHHFFFFFFEEEEEEDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDB<B
@3UT
GTTCACACTTTGTCAGATGAGAAATGGGATGTTATTAACTGGAGGAGGGAAAGACAGAAAAATAATTCTGTGGGATCATGATCTGAATCCTGAAAGAGAA
+
???B?+?:;D3:A<<A:ACEECADF?FIDFB9*9C4??:?DC*?@:DDD6;D;38==;>==;;A>CC=3==?=?2;;>(6;>AA(;>3((-5:>AA999>
@3UU
CTTAGCCGTTCACTCCGCTATTACTATGAGAAAGGAATTATGCAAAAGGTGGCTGGAGAGAGATATGTCTACAAGTTTGTGTGTGATCCAGAAGCCCTTTT
+
@<@?DDDDHH>DFFGIIIGGGIIEEEHGHGHIIFHADHGIIIGIIIIIIDHGHHHGGGHA@@;EEEFHDDF@DDCACDEECD=;?5>>>>@:CCCBDDDDC
@3UV
GGGACTTCAGACATTAACCATGACAAATTCAGGCAGTACTCAGCAAGGTACAACTATTCTTCAGTATGCACAGACCTCTGATGGACAGCAGATACTTGTGC
+
@@@DDDAFDFDFHIEIIHGJJHH@FHCHHGIJIJIIIIDCHIIHJGHGD99DHIIHHIIIIEHIAGGIIJGIIIIFIEHHCEHFDEFFDDC9ADACDDDDD
@3UW
AGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACAACGCCCAGCCCACTCAAGGATATGCACAGACC
+
<@@BDDDDHB6C?FEDGH>FAFGIIII>CG@B@BBHBDCHIIIGIIIFGII@CE>BBEE@@>>>C>C>>CCBBBBBBBB?BBBCCCCC8>:ACCDCA?CBB
@3UX
CCAGGGCCTTGGAAGCACTTTGCCTAGAAGGGGAACCAGGAATGCCATAGTTCCGAGAGAAACTTCTGTTAGTAAAACACACAGGTCAGCAGACAGGGCC
+
???BD)ABD<D<:C:E?E3<:?FE922:::E)0CDDIDD;B23//??C=./8=CDAA8A;7=?..;;76>AA.;@AA>>??/<??AAA9552382+28(8
@3UY
AGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCAC
+
CCCFFFFFHHHHHJJJJJEHIJJJJJJJJGHIJJJJJJJJJJJJJJJJJJJJJJJIJJJJIJJJJHHHFFFFDEDEEDDDEDDDDDDDDDDDDDDDEDDDD
@3UZ
GTCCTTGACCTCGGCAAGGCCTTCAATTCCAACTAGCCCACATTGGCCCCGATGGACAAAGCCCTGAGCAACTGATCAGCGACCTGCTTCAAGGTGGAAA
+
1+:++<A4<<+2+)<71+<+++2+*1@*1:**17*1)0?=1)***1=A2''-55A))7()7)..).5>9((((-(-((,('',&)(+((((+(+(((++8
@3V0
CAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGG
+
?@@BDFDDFHGDD@@FFHIIEEEE@CHCHDDB?DB?DGDED;BGGGHHHIEBHGDHICBHEF>DGHIIGHHGCB=(?CCCEECACCDC:?CAB@<50?>@B
@3V1
AGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACC
+
@<?DDDBBBDFHGIIGB@CEFGHIGFGIIGIGGIIDHGGEGGGIIFIIIDHGEHGFDBDFEEEDEDDDDDDBBDD>BDDDBD?CCCAC?>CCDCDDDDCDB
@3V2
CACCAGCTGAAAAGTCACATAATTCTTGGGAAAATTCAGATGATAGCCGTAATAAATTGTCGAAAATACCTTCAACACCCAAATTAATACCAAAAGTTACC
+
BCBFFFFFHHHHHJGIIJJJJJJJJJJJJIIIIJJJHIIFHIJJJIIJIGIJJJJJIJJEIJIIJJJJJHHHHHHBDFFDDDEDDDDEEDDDDDDDCDDDD
@3V3
CGGGCAGATCCAGCTGTGGCAATTCCTCCTGGAGCTGCTCTCCGACAGCGCCAACGCCAGCTGTATCACCTGGGAGGGGACCAACGGGGAGTTCAAAATG
+
1?@D;D8B?FFBFFB<?@?AFFGIFIE?E>D@ADGFFEBDDGI@@FFFEFIABBAABD@95>A@AAB>@?:>??<?<BB>9@18??@BB-52>@ADBBAA
@3V4
CTCTACAACCCCACGTCAGAGTGTGGGATTCTGTTACTCTATCCACACTGCAGATTATTGGACTTGGCACTTTTGAGCGTGGAGTAGGATGCCTGGATTTT
+
CCCFFFFFHHHHHJJJJJJGIFHGHJJJJJJJJJIJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJHHHHHFFFFDEDBDDBD@CCDCDDDDDDDDDDDD
@3V5
CAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCC
+
?;<7DDAD1ACD4EEE3):8?D8?30?D?B<DB4**0-)8.=AC;@78@.=7A7=A=A=(7;@AA>@@??6=359?=??55:>:<><AAAAA:>::3(2<
@3V6
CTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGACTGCATCAGGAGATATGCAAACATATCAGATCCGAACTACACCTTCAGCTACTCCT
+
CCCFFFFEDHHHHJJIIJJJCHIHJJJJIJIGGJIIIIJIJJJJIJJIJJJJJIJJIIEIJJJHHHHHFFFFFFCEEED@DDDCCCDDDDDDDDDCDDDDC
@3V7
AATCAGCGTCCACTGCTGAAGACAGACATGGAACGTCACATCAACGAGGAGGACACAGTGCCTCTTTCTCACTTTGATGAGAGCATGGCCTACATGCCGG
+
@@@FFDDDFADFHIBHGICGGCGIIH?EFGGGHGIGICCHGIIIIIIGGGIGDAEHEEEEEHFBDDCBCCDEDEEDDDDCC@CDDDDDBDDDDDDDCCDD
@3V8
TGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTAT
+
C<@FFFFFFFHHFIGJIHHIJIJJIIIJJIJJIGGIIJJJJJIGHGIJJIIGIJJJJJIEIIHHFFFDEEDEEDDDCDCCCDCCDDDCDDDDDBDDCDDD
@3V9
GTGAGATGGATGCTGTAGGCTTGGAGCTGCCTGTACAAATAGAGGAGGTCATAGAGAGCTTCCAAGTTGAGAAGTGTGTAACTGAGTATCAGGAAG
+
@@@DFFFFHHHGHJJFHHIGGHHHIIIDHGIJIHIJJJGIJJIJJ>FG?FHGIIHIEGGJIJJJJHCDHGGHFH7?7?@CDBEC@C;ACDD@C;AB
@3VA
GTGGATTTCAAACAGTCCAGGCTCTCCGAGGACGGGCTGCATAGGGAAGGGAAGCCCATCAACCTCTCTCATCGGGAAGACCTGGCTTACATGAACCACAT
+
@?;DDBDDBDHFDHBFHG@<CD3A<CBCFE@@BHIBGIID87;FG>7@EGH?E;BBBA@A@>?BCCCC>AC@@?B@B>0<CCCCBBC?:>AC:@CCBBB?C
@3VB
CAGCGGCTGGCTGAGCTCCAGGAGCAGCTCAAAGCCGTGCACGAGCAGCTTGCAGCCCTCTCTCAGCCCCAGCAGAACAAACCAAAGAAAAAGGAGAA
+
@@@FDADF>?DFD>GG@FGHIHE=;:?B@D@D@?;FFF0AFFG8BHBE=?EB=D;BC=6=;?>AA5>C8=?B?C<AA<A?B<8?8A3989A?@?8?8<
@3VC
GCCAAGGGAAGGACGTCCTATGTACCAACGCCAGATGTCTGAGCCAAACATACCCTTCCCACCACAAGGCTTTAAGCAGGAGTACCACGACCCAGTGTATG
+
1;8DDBDDDFDFFFIF>E;BFCF<EB:E;8?60@;DGF>9B<<FFIFI=@F)8@AE;=?976<B=BC@@CB?>AA:ABB@8?9>::;@8059@<?:A(:B>
@3VD
CGCCCATGAAGAGCAAGCCCCCTCCCACGTATGAGTCGGAGGAAGAGGACAAGTGCAAGCCTATGTCCTATGAGGAGAAGCGGCAGCTCAGCTTGGACATC
+
@@;DD:DDFDHFBFFGFAEHBC8ECH?;@?BDBEG0B@B?@@DAEHI=26ACE=C<BB>??ACC>.;C>>@@5>35<<?C9;<9BB@<CA>AC49<CC(4@
@3VE
GCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGC
+
@@CFFEBDFFHHGGJGEGEDBHDAGHGGIIIJIIICFEGGHHGIJGIIIGIIJEGAHGEEH9CCEHHGB>?BCED?ECDDCAA@CC@@ACDDDCDB@BCCC
@3VF
CCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTC
+
@C@FDFFFFHHFGJGDCFH@EGEHJEGEGGGIGGJJGJGIIIJGGIJGIGIIGGGCEHEHIGJJJBHEFFCEACDEECDCDCCCDDDCDDDDDCDCDDCDD
@3VG
CTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACC
+
@B@FFFFFGFHDFJIJJJJJJJJJJJJIJJJJIJIJJJJJJIJJJIJJJJJJJGHHHHFFFFFD>AEEEDDDDEEDDDDDDDDCDDDDCDEDDDDDDDDDD
@3VH
TCCCAGCAGAACAGAAGGCTGTATGTTTGAAAAGGGCCCCAGGCAGTTTTATGATGACACCTGTGTTGTCCCAGAAAAATTCGATGGAGACATCAAACA
+
CCCFFFFFHGHHHIJJJIJJIJJJGHIIIIIJIJJJJJIIJIIJJJIIIJIIIGHIJJIIIIIHHHHHCFFFFFFEDEDEDDDDDEBDAABDDDDDDDD
@3VI
GAAGAAATTGCTCAAAGATGCCATGAACTGGATATGCAGGTTGCAGCATTGCAGGAAGAGAAAAGTAGTTTGTTGGCAGAGAATCAGGTATTAATGGAA
+
@@CFFFFFDFDFHGIAFGIHIGHEGGBEHGGGBDGHCDFE8CFBHIGIJJJ@BFBFG@GDFDHIG7@@@>GH;@CEAEBB;@C@CCEC>C@@ACDCCCA
@3VJ
AAGAGAATAAAAAAAGCAAAGCCAAGGAACCTCCTCCTAAAAAGACGAAGAAAAATAATAGCAGCAACAGCAATGTGAGCAAGAAGGAGCCAGCGCCCATG
+
BC@FFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJHHHHFFFFFFEEEEEEDDDDDDDDDEEDDDDDDDDDDDDDDDDDDDDDDD
@3VK
ATTGGATCTGGATCATTTGGAACAGTCTACAAGGGAAAGTGGCATGGTGATGTGGCAGTGAAAATGTTGAATGTGACAGCACCTACACCTCAGCAGTTAC
+
@@@DDDDAFFFFF>EFG@HE?EEFF<BEHFEFFFIEC=F*?D;DCFF9B49B9FG2?F8C=CDA4@@AEBE:@.===?A;@2?@>@C9ABB>?>A?5:>:
@3VL
TGAAATTAGAGCTGACTAATTCTAAGCAAAAAGAAAGACAGTCTTCTGAAGAAATAAAACAGTTAATGGGGACAGTCGAAGAACTTCAGAAGAGAAATCAT
+
??@ABD?DDHFHFEBEHF???FEHFCFGHH>G@GEHIHEEGDGDHIICHG?9D@?FIIII?GF8C@FIIID;@CEHHD=DAA>;A@>CCCCAC?<CC@>C>
@3VM
AAAAATTCGATGGAGACATCAAACAAGAGCCAGGAATGTATCGGGAAGGACCCACATACCAACGGCGAGGATCACTTCAGCTCTGGCAGTTTTTGGTAGCT
+
@@@DFDBBDHAFHGGHGIIIIGEHEGGGIIIG@FFBFAFHABHGEHHBDG;6;FCDCH@3=AA;9<>=8659>ACCC@C>>CDDCDDDB<:A@BB9<A>CA
@3VN
CCAGAAACAAGCCCACCAGCTTGTGGAACCCAACGTACGGCTCCTGGTTTACAGAGAAACCCACCAAAAAGAATAATCCTATAGCAAAGAAGGAGCCACAC
+
CCCFFFFFHHHHHJJJJJJJJJJGIJIJIJJJJJJGJJJIIJJJIJJHIJJIIGGHFHHHFFFDDDDDDDDBDDDDEDDDDDDEDDDDDDDDDDDDDDDDD
@3VO
GTTTTTGGTAGCTCTTCTGGATGACCCTTCAAATTCTCATTTTATTGCCTGGACTGGTCGAGGCATGGAATTTAAACTGATTGAGCCTGAAGAGGTGGCCC
+
??;+AA?D+ACDAC:E@>@:CBEC<ACCE;:C??CDCD?::?D>>D9?BDDDIDD98BC@4@;@=CC>A;@ADDDA;A@A@A;;;5(;=?A>A59(52(28
@3VP
CAAAAATAATAGAAGAAGAAAAGAAAACTCTTGAGCTAAAGGATAAATTAACAACTGCTGATAAATTACTAGGAGAATTACAAGAACAGATTGTGCAAA
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJIIJJJJJHHHGHHFFFFFEEEEEEDCCDEDD
@3VQ
GGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTAC
+
7++<??;2?<AA8==BB@B>B<*?=BB;A4:AABB?A>*0==B>BBB>BB9AABA>B;=AA9(..7.;=>>@@@;=?>=========;2:=798;;?=?
@3VR
CCAGGAATGTATCGGGAAGGACCCACATACCAACGGCGAGGATCACTTCAGCTCTGGCAGTTTTTGGTAGCTCTTCTGGATGACCCTTCAAATTCTCATTT
+
@CCFFFFFHHHHGJJJGIJJJJJJJJJJJIJJJJJIJJJJHHHFFFFFFEEEEEEDDDDDCCDDBDD?CDDDDDDDDDDCDDDDDDDDDDDDCDDEDDEEE
@3VS
TGAAAACACTTGGTAGACGGGACTCGAGTGATGATTGGGAGATTCCTGATGGGCAGATTACAGTGGGACAAAGAATTGGATCTGGATCATTTGGAACAGTC
+
0-3((@)@3)=8@;??>195(-28)1@4.(==.).<<>9>5(99:1:>3)337=?;=8>=8.36=0;3639=;9=8=7;((--4,,:(,28;66(:8/2:(
@3VT
CCAAGCCCTCGAGCAGTTATTCCCATGTCCTGTATAACCAATGGAAGTGGTGCAAACAGAAAACCAAGTCATACCAGTGCTGTCTCAATTGCAGGAAA
+
@@@DFFFFHHGAFIIIFHHEHJJJJIIGIGJGFGGIIIIGIIDDFI;?FD??BFEHII@CHIJJJJHG>CEEFEFEE@CCDEEEC>CCCDDCCCDDDD
@3VU
CCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGG
+
?<?1B:A2C:DD>EE9CE3<CFBF<+A<9CC*:?9?DDDD@DDDI@BDDEIDDB28<=;'@84A5=6?@?@@6;@DEA>8;=8<?(9(+5&8>+:>>++48
@3VV
GGGGGGGTAGGGAAAGAGTGTAGATCTCGGGGGTGGGGGTATGATGAAAAAAAAAGGGGAGAAGGCGATGGGGGGGGGGGGAGGGGGGGGGGGGTGGGG
+
(;(=?'&)08--(++(82+6626:62((+(&))&&)0&0&&((((((((+())0&&((&&)&(++(&&)&&(+&)5&)&&&)&)0069&555)&&)00&
@3VW
CTCCCACGTATGAGTCGGAGGAAGAGGACAAGTGCAAGCCTATGTCCTATGAGGAGAAGCGGCAGCTCAGCTTGGACATCAACAAGCTCCCCGGCGAGA
+
CCCFFFFFHHHGHIHJJJJJJJJJIJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJIJJHHFFDDDDDDDDDDDDCDDDDDDDDDDDDDDDDDDDDDDD
@3VX
CTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGG
+
CCCFFFFFHHHHHJIHIIJJJJIJJJJIIIJIJJJJJIFIIJJJJJJJJIIIIIJHHHGHFFFFEDDDDDDDCDCDDDDCDDDDDDDDDCDDDDDDDDDDD
@3VY
GGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGC
+
@?@?;DAAF8FHDFG>DFFG>@EG?GCGH@HGIICHGGGFBDEHI;FGGHII@FFG3CG@A@ACEAEEED?CC@ACC;A@@CAC@:>::<55?>CCCCB
@3VZ
CAAAGTCCACAAATTCGAGCATCACCTTCTCCCCAGCCCTCTTCACAACCTCTCCAAATACACAGACAAACTCCAGAAAGCAAGAATGCTACTCCCACCA
+
@@@:A=ABDFFHB@GIIICFBBHGIGIGFBF?9?CCCFCGGGGIGCGHIGF@=@BCFDEG@H@GAEEE=A?@D@@;;>C@<ACCCC@ACC@>>ACBC<@B
@3W0
CCAGAGACCTCCTGCTCCTGAGGCACCCAAGGAGATCCCACCAGAAGCTGTGAAGGAGTATGTTGACATCATGGAATGGCTGGTGGGGACTCACTTGGCC
+
?=<BD?++=<+ADBA>B<CCEECDE;CEC;D;D=DDD*?@DDDDI3B@=BEE;CE>AAA;CDIA>CCDACDAA>;63>3.;;'5;5;??&(+:3+::4+:
@3W1
CGTGGGAGAAATTGTAACGAGAAACCAACAAATGTCAGGAAAAGAAAATTCATTAACAGAGATCTGGCTCATGATTCAGAAGAACTCTTTCAAGATCTA
+
@@@ADD;2@DDFDIFGIIFIDIFICEG@BCE@9??D<FGFFFIEFFFF)=CFF<FGGEAFI3=DAAEEF>?).;@:BC>ACCBB3;@BBBBB@>:@BDB
@3W2
GGCGCCTTTGGGGAGGTGTATGAAGGCCAGGTGTCCGGAATGCCCAACGACCCAAGCCCCCTGCAAGTGGCTGTGAAGACGCTGCCTGAAGTGTGCTCTG
+
CCCFDFDFDFDH@FG<AFHCHIIEHGGIFIIAG9BFHIGGGGGGIIIIFIHHFFED?CDDDBBBCCD:ACDBD?C>A@A?5955>ACDCCC4:4@>CDCC
@3W3
AAGGAGGTGCCGCGGAAAAACATCACCCTCATTCGGGGGCTGGGCCATGGCGCCTTTGGGGCGGAGTATGAAGGCCAGGTGTCCGGAATGCCCAACGACCC
+
8=;D>DD++22<)@C@C?;DAD3?9/)/(8B8BCC>88//9='5<=<9>3<&7<?<A:93-&)5&)+3>(4:>9<8(2(+++4><??30(:33><?>8505
@3W4
TGGAACGTCACATCAACGAGGAGGACACAGTGCCTCTTTCTCACTTTGATGAGAGCATGGCCTACATGCCGGAAGGGGGCTGCTGCAACCCCCACCCCTAC
+
@<8B?DABFHFHHIIGAHIIIIDBHHIIIGBDEEGGHIIIGFHGEDDFHGICHEG@CFHFBAHEHFAECED?AB@BB@B@BBB:@ACC@@>BB<B<BBB@B
@3W5
CAGATTCAGAGAGCTAGACAGACAATAGCTGAACAAGAAAGTAAACTTAATGAAGCACATAAGTCCCTTAGTACAGTGGAAGATTTGAAAGCTGAGATTGT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJIHJJJJJJJJJJJJJJJJJJJJHJJJJIIJGIIJJDEHHHHFFFFFFEEEEEEDDDCDDC
@3W6
CTCAGCGACACTACCTGGGCCATAAAGACTGTGTGAAATGCCTTGCTATACATCCTGACAAAATTAGGATTGCAACTGGACAGATAGCTGGCGTGGATAA
+
CCCFFFFFHHGHHJJJJJJJJJJJJJJIGIJDHHJJJJEHIJJJIJIIJJJJJJJJJJJJJJJJJHHHHHHFFFFFEEEEEDDDDDDDDDDDD@BDBDED
@3W7
CCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGAGTTTATGGG
+
=+:A:B32AAADA93<<AA+3ACD<EFFI<BE1CE<CD*?DDI)?9*8(70;81=@@@7.)7?CA;A6'9<;=???>78?18>>:(:>A<2(+++4>:4:>
@3W8
CTGGGAAGCGAGCTCTAGCTGGAGGTCCAGCCCCTACTGAAAAGACACCCCACTCAGGAGCTCAACTTGGGGTCCCCAGGGAGAAACCCCTAGCTCTGGG
+
@?@D+B?DHFAFAAEEGDEE@GF>;?@FH?FGHBA8938BDHE*<))8;@<5'677;=?B;?@CACCC@C@B?BBBB<8?B899B?>8+9(8?C@ACACC
@3W9
CTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTC
+
@C@FFFFFFDHGHEGJGGIIIGIIHIJJJJJJJGBDHIJGGCC?B@FGEHIGHEC9CAGAFHECEC7CH>DDDDCBCDDDDCDCB?D?AB>ACA>ACCDAC
@3WA
CAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJGJIHHHHHHFFFFFEEEEEEDDDDDDDDDDD@DDDDDDDDDDDDDDDDD
@3WB
CTTCAGACATTAACCATGACAAATTCAGGCAGTACTCAGCAAGGTACAACTATTCTTCAGTATGCACAGACCTCTGATGGACAGCAGATACTTGTGCCC
+
@@@ADDDADAFHHIID>GBGHDEEGHIGBFFGHIIIIIEBEGGC?D@DEHDGEB@FAGHGI<FGIIIDCHE@;CEGHCHFEHED?CEC@CCCAACCCCC
@3WC
AGATGATGGAAAGTGAGTTGGCTGGGAAGCAGCATGAGATTGAAGAGCTAAACAGAGAGCTGGAAGAAATGAGGGTTACCTATGGGACTGAAGGACTGC
+
=?=:=:D:+2=AD:AE:AE@F@D@1?A+C?CBEDA@B@@BDB@?<DCDBDCDED3.=B;;ACDDIEDEDDD@CDD=ADAAAAAAAA????5(::99>??
@3WD
CTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTAT
+
CCCFFFFFHHHHHJJJJJJJJJJJJIJJJJJIIJJJJIJJJBHIJJJJIJJHFEFHHFFFFFFEEEEDDDDDDDDDDDEDDDDCDDDDDDDDDDDDDDDDD
@3WE
GGCAAAGCTCAAACAAAGAGCCCCGTACCCCCATTGTCTGAAGGCAATGCTGGCAGGCGGCTCCATTATCATGCTCTTACGGGAAACTTTATTAAAGCCAC
+
07(((2)2))22)2(::96)22(2(((-::((-)))00))00))((9.77=;95)(--33,,',,,:5=2;=0;3(522/2&&&&+((4++++(((++(++
@3WF
TGTGACAGCACCTACACCTCAGCAGTTACAAGCCTTCAAAAATGAAGTAGGAGTACTCAGGAAAACACGACATGTGAATATCCTACTCTTCATGGGCTATT
+
@@@DFFDDDDFHHEGIIIGHIIIIGCHEEHIEDGGGCGEHGGHDGGG<BFDBG?BBGGG@EHIGHJ@GE<ADD>?CDDDDCEE>@CCCCCCDCCCBBCBCC
@3WG
CAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCAC
+
?<?DDFADFFHDHGHIJIIIIHIJIIIJIID<FHHGGHGGHGGEIHGIJJEBHGAGGHIG>AEEHFHHBDCBDFCEAEDDBDCDDDDDDDBBABB?CBDDD
@3WH
GAAAAACTTGAGGCAACCAAGCGAGAGAAATTAGAGCTGTCACAGAGACTGTCTGATCTTTCTGAACAATTGAAACAGAAACATGGAGAGATTAGTTTTCT
+
:=:7+@)?<27C=+2+22<=<?<+:)01:==7*0**:9009*09?*>B;=A)>==B7=A=7>7....7.=>;77).)(;5>>3-;5(,;=8>;9;559=>3
@3WI
GATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCC
+
CC@FFFFFHHHDHEGGIIJJIIGIJGGGIIHIGEAFHHIJJJFGHHJJJJIIIIIHIJJJJHHEHEHFFFFDEFEDDDE;ACDBDDDDDDBDDDDDDDD?B
@3WJ
CGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCG
+
@<@DFF?BFHD?FBFGGII@DEHCB??:DFCBD3DD<)=AFFGCACAE>B@DACEEE>A:@AAACACA?::>?AC<>@B-?AB<BBBC@:+:>ACCCCCCD
@3WK
GATCAAACTTATAGATATTGCACGACAGACTGCACAGGGCATGGATTACTTACACGCCAAGTCAATCATCCACAGAGACCTCAAGAGTAATAATATATTTC
+
==::B?+2AA?CFHICFHH?A<::@<<:C1CGDDGIDG=FDFDF<9?8BBG988BB/;@8=E;AAEHEED;?CC96;@;=5@(-,(,,,5,;;5@D;;;::
@3WL
GTTGCTCTGCTGTCTTGTGTTTTTGCAGCCTCTACAACCCCACGTCAGAGTGTGGGATTCTGTTACTCTATCCACACTGCAGATTATTGGACTTGGCACTT
+
B@BFFDFFGGHHHJJJJHEIIJJJIHJJJJJIIJJIJJJJIIIIIIJIBHCG=CHHAGIEGGIHGHHGHEFFFFFDDEEECDCCDDDEDDCCCDDDDCDCD
@3WM
GAAAGTTAGAACAACTCCGGGCAGAGCTGGATGAGATGTATGGGCAGCAGATAGTGCAAATGAAACAAGAATTAATAAGACAACACATGGCACAGATGG
+
;7<:BADDA?<2:?+C+:+@DEE6EE9DE9C??DA*0*09B<)?(8.688B3AC/8@ACD:4ACDDCD;;77?A;6@A@A>A>5;(,:395:5(55:AA
@3WN
CTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIIHHHHHHFFFFFFDDDDDDDDDDDDDDDDDDDDEDDD9@BD
@3WO
TCCAGAAGCCCTTTTCTCCATGGCCTTTCCAGATAATCAGCGTCCACTGCTGAAGACAGACATGGAACGTCACATCAACGAGGAGGACACAGTGCCTCTTT
+
@BCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJIJJJJIIJJJJJJJJJJJJHHHHFFFFFEEDDDDDDD@DDDDDDDDDDDDDD
@3WP
TGCGTCCCTTTCTCCATAAAATTCTTCTTAGTAGCTATTACCTTCTTATTATTTGATCTAGAAATTGCCCTCCTGTTACCCCTACCATGAGCCCTACAAAC
+
1:+22<?<?BA4,222?4ABA@A7A><@<A7:1@A@4?=*?:::=:00=A*=*7?=?BB97?<<>>A4)=>=A>)=)77AA9((((.;>5;3(5;555((5
@3WQ
CTTGTGCCCAGCAATCAGGTGGTCGTACAAACTGCATCAGGAGATATGCAAACATATCAGATCCGAACTACACCTTCAGCTACTTCTCTGCCACAAACTGT
+
C@@FFFFFHDHHHJJJIJJIIJCFHHIGJIJIJJIIJJJJIIIIJJJJJJIJJJJJIJJJIIIJIJGHHFFFFFEEEEEEDDDDDDDDDDDDDDDDDBDD@
@3WR
CTCGGGTATGGTGTACCTGGCCTCCCAGCACTTTGTGCACAGAGACCTGGCCACCAGGAACTGCCTGGTTGGAGCGAATCTGCTAGTGAAGATTGGGGACT
+
??8A=)A?<C?DD+AA:,A+<:+AFB?:):1:D9C9B?:?*?09B;6?DD<8B;B@@DD@@7=C?)=;))5=(6>;63;<(;(((5(:>AA4:>A?<>(51
@3WS
CCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTTATGGG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJIJJJJJJJIJJJIJJJJJJJJIIJJJJJJJJIIJHHHHHHFFDDDDDDDDDDDDDCDDDDEDDDABBDDDDDDD
@3WT
CGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCT
+
CCCFFFFFHHHHHJJJJIJJJJIJJJJIJJJGIIJJJJJIJJJJJJJJJJJJIJJIIJJJJJJJJJHHHHHHFFFFDDDDDDDDDDDDDDDDDDDDDDDDC
@3WU
ATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACC
+
=1+2<=@A+22<=3?<1A?<7<C++)15AB;*11:::=*:><=ABA<=BA=B<=B4A=2>=6'-',7..76>(.6(6-;;>;-;9535;5,,,59((+389
@3WV
CTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTAT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJIJJIJJJJJJJJGHIJJJIJJJH?EHHHFFFFFFEEEEDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDD
@3WW
GACCACTGCAACCTATGGTCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTG
+
@@@FDFFDGHBHHCIIAECHHIJGIGBGGGGHBFHGIIGHJJIJJIGG=FBEFGGCECGHIFHHGFHFFFFFDAACCEDD@DDB@BDDDDDDCCBDDDD<8
@3WX
CCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATAC
+
CCCFFFFFHHFBFHEEHGIIJJIJIGGGIJIJJJJIIIGIIIFICHIJIIIHJJIGJIIHHHHFFCFEEBCEDCCDDDDDDDDCDDCDCDDDD>?@BDCCC
@3WY
CTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJBHJJJJJJJJJJJJJJJIJJIJJJJJJJJJJJJJJJJJHHHHFFFFFFEDEEEEEDDDDDDDDDDDDDDDDDD
@3WZ
GCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGC
+
CCCFFFFFHHHHHJJJJJJJJJJJJIJJJJJIJJJJJJJJJJIJJHJJJJJJJIJJJJJJJJJJJHHHHHHFFFFFFEEEDEDDDDDDDDDDDDDDDDD
@3X0
CGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTT
+
@@@FDADBHHHGHGIIGGGIIEIEB;FGGGIIGHGIGDEGBFHGEHHIIIGHHHJIFIJFACED@D@DCCD@@@BDDCCCCCC@B8>CAC8ACCCB>CACD
@3X1
GCACAGACCACCCAGGCATATGCGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGC
+
=11=22<?C>=?<=9+@=+3+<+)1:?AB<B9AA?773<=;1;=)7>4>.-==AA5(=>)=.=;;;37);>@@>@:;(;;(:3,,953(,:823:::(29
@3X2
CTTTTCTCTTGGATATATGCCATACCCCAGCAAAAGCAACCAGGAAGTTCTGGAGTTTGTCACCAGTGGAGGCCGGATGGACCCACCCAAGAACTGCCCTG
+
@<<ABDDFHFHDFAGDDFHIICEEGHIBHB>CGGCCCHHCGGG?DGC9B?FF@FB=B<F;=@GG>GGGG76;AC9<'9;B9CCBBBBBBB?29<>ACCB>A
@3X3
AGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAAC
+
;@?DDDABDHFHFIGHEDDIIIGEGGHGIIECFFFHHDEHDFEHGCCHCHID@@@@>==@@@CHIHHBEEEEFF>DDC;>CEC>;ACC??BDCDDDBBC@A
@3X4
ACCAACTTCAGTTATTCAGAAATTTTTTCTTAAATAGCATTTATAAGTCCAGAGATGAAGCAAACAACAGTGGAGTCATAAATGAAAGCTTTGAAGGTGA
+
CCCFFFFFHHHHHJJIJIHJIJJJIJJJIJJJIJJJJJJIIIJIIIIFIIJIJJJJJJJHGGIJJJGCHGCHGGFHHHGFFFFFFFEEEEEEDDDDD?CD
@3X5
TTTAACTCTTGGTCATCAGCCTTATCCAGCTCATTCCAACCTTGATGTGTTAAACTATGTGCAAACAGGAGGGAGACTGGAGCCACCA
+
CCCFFFFFHGHHFHIJJJJJJJJJIJJIJJJIJJJJJJJEIJJJJJJFDHHIIJJJJJJJJIJIJJGIJIIJJHHEEFFFEEEDEDDD
@3X6
CCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTTATGGG
+
CC@FFFFDHGFHFGIJIIGEHGIIJIGEGHIIIIGGIJJJJGIIJGGGIGGHIJJDGHIIIHEHHHHFFDDCABBBDDDDDD:CCCCDCDB?B9<CCDDDB
@3X7
GGCGTTCGCAAGTGCAAGCCCCAGATGAATTACGACAAGCTGAGCCGGGCCCTGCGCTATTACTATAACAAGCGCATTCTGCACAAGACCAAGGGGAAACG
+
+:?D:?DDFFAF?EEBDFFIFIIIIIIEEBBBFFDFIFEIFIIFIIFIIEBDDCC>@B@@BBAAA>AABBB98?BBBBBDABA:A@83?@BBBB?B59BBB
@3X8
GGAGTTTGAGGCTGAGGAGATGCAGATTCAGAACACACAGCTGATGAATGGGACTCAGGGCCTGTCTCCTGCAACCCCTTTGAAACTTGATCCTCTAGGGC
+
;8??A?BDBBDF:<3CEE;AFH499F>?1:11?DEFF)B9@*9?F<B<DFF2)8;FC7.=1@757?AA:=:;7;BDCCCBA3@>@AAAA@@@@A:(:>:19
@3X9
GGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCC
+
@@?DDFFFHHDFHIJGIIGIJJJJHGHHHIGIJJEHIJIJJGIJIIJIJJI;BEEHHFFDFF@CCECEECDDDDDCDDDDCDDDDCDCB:>CDDDD<BDD
@3XA
CAAACTGCATCAGGAGATATGCAAACATATCAGATCCGAACTACACCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATGACATCTCCTGTGACTCTCAC
+
CCCFFFFFHHHHGIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIIJJJHHHEHH@DFFFEEEEEEDDDDDDEDDDDDDD
@3XB
GGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGC
+
@@CFFDFFHGFHHIGDDEG?EGCFHDGGIIIGGHIHGEHGGIIGIJGFHHEFFEFCDDC@CAEEDDDBCDACCC;=BBBDDDDDDDDDD@ACECCCCCDDD
@3XC
CAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCAC
+
CCCFFFFFHHHHHJJJJJJJIJJJJJJ@GHIIJJJJJJJJJJJJJIIIJIGIJJJJJIJCGHHHHHHHBDFFFFDE@CDDBCDDDDBDDDDBBDDCDDDDD
@3XD
TCCAAATCCAAAGACTCTGTGTGGGAAAAAGAAATAGAAATACTTATAGAGGAAAATGAGGACCTCAAACAACAATGTATTCAGCTAAATGAAGAGATTG
+
@@@DFFFFHHGHHGHHHIIHGHHIJEHIIIIHJJIGIIIJIJIIJJIJJFIEIIHGIIIIJGGJJJJIIIHHFHFFFEFFEEEECEEDDDECDDDDDDDD
@3XE
CCAAAGCTTTCCCCCTCCTCTGATGATTAAACAGGAACCCAGAGATTTTGCATATGACTCAGAAGTGCCTAGCTGCCACTCCATTTATATGAGGCAAGA
+
CCCFFFFFHHHHHJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJIJJJJJJJJJHGIIJHHHHHHFFFFFEEEFEEEEEEEDDDDDDD
@3XF
TGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTC
+
@@@FFDADHBFBHEHIIBIIGIGGCEHIH<BGHIIGCBDHHCHIGHGIDHBHCFHAGHIIGGGEFDFCAECBCACCCA?ABBBCBCCC@CCCCCCECCA>C
@3XG
GGGGCGTTCGCAAGTGCAAGCCCCAGAGGAATTACGACAAGCTGAGCCGGGCCCTGCGCTATTACTATAACAAGCGCATTCTGCACAAGACCAAGGGGAA
+
@@@DADDAFDDHHJGHHIIGGAFDHHH(<FGBFC@GCHIHGAE?;?CDDDB?BD<??<B<;BCCCCEDCDCCDCBBDBD>CDCD@CCD?C?CCBABDD9B
@3XH
AAAGATTGATTTTCTTAGAATCCATTAAGTCCAAATCCAAAGACTCTGTGTGGGAAAAAGAAATAGAAATACTTATAGAGGAAAATGAGGACCTCAAACA
+
5;33=6@6)29@8;:)@4>)@))).=;).@9.<@8:>?8;899.=9))).)0(0.)9>?3=111:63)))))8>636::=;(()83(69;>(9((699(8
@3XI
GGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATG
+
??<DDDDBBBFHHGC@FGGHEIHGIIGIIIHG>F?BFHCFCDEHIIIIDGGA@CEEE<DEA?>?BDDCA>ACCADDCDDDDDBDB@?B?@@?CDCCDDCAC
@3XJ
CCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTTATGGGCAGGAGT
+
7:=7A<A++?=A>74,,<CC77<73?<A@A3?@3@=3:*:?A0:.758ABA).=A>AB474':51><==6====859353;>25,0&88338:((9.59<8
@3XK
ATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHHHHFFFFFFFDDDEDDDDDDDDDDDDDDDDDDDDD
@3XL
CATCCTCAGAAGACAGGAATCGAATGAAAACACTTGGTAGACGGGACTCGAGTGATGATTGGGAGGTTCCTGATGGGCAGATTACAGGGGGACAAAGAATT
+
><7AAAAA=BA8=C=@+<=3@C7?+<2<?**11:?<31?07004))<9);(')./=A.===A5((',.;>;3(;;;(;53,55(,:9(8300&288(9;:(
@3XM
TTTCTTTTGAAAATATGACTGTTGGAGAAGAAAGTAAGCAAGAACAGTTGATTTTGGATCACTTACCATCTGTAACAAAGGAATCATCACTTAGAGCAACT
+
CCCFFFFFHHHHHJJJJIJJJJJJJJJJJJJJJJGHJJJJJJIJJIJJJIIJJJJJJJJJJJJJJJJJJJJJIIJJHHHHHFFFFFEEDEEEEDDDDDDDD
@3XN
CGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCG
+
BCCDFFDDHGHGHIJIIGGIGGEGIIFJIIIGIJIGEGHGIGHIIEEHFFFFEEED@CEDDDDDDDDBBDCCCDABBBBDBAB<B?ACDC:ACDDCDDDDB
@3XO
CCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTA
+
CCCFFFFFGGHHHJIJJJJJIJJIJJJJJJJJJJGJJJIIJHIEHIJJIJJJJIJIGIIHGHHFD?BDDDDDBDBDDDDDDDDCCDCCDDDDDDCBDDDD
@3XP
CAGACGTGGCGACCCGCTGAATTTAAGCATATTAGTCAGCGGAGGAGAAGAAACTAACCAGGATTCCCTCAGTAACGGCGAGGGAACAGGGAAGAGCGTCG
+
==72<82+?C8)7?AA<AA0?*:?=A??A*07*9=ABBB9'4;4455=@9>>>>>35;;(;899;=95;(59(383(&&&-9&)59(++88(+(++35&()
@3XQ
GGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATAC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHFFFFEEEEEEEDDDDDDDDDDDDDDDDDDDDDCDDDED
@3XR
CTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTAC
+
@@<DD?BD<=AA4?AE;<ACBFCA9CHA3A+CFDG:?FFIFDFFB=FFFED@E>EEA>BDB>@D?@6.;@@@BAABBBBBBBBB@<@:::A@:?B(858@B
@3XS
TACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGC
+
CCCFFFFFHHHHHIJJJJJJJJJJJJJJJJJJJJIIJIJIGIIJJJJJJJJJIJJJJIIJIJIJJIJHHHGFFFFFFEEEDDDDDDDDDDDDDDDDDDDD
@3XT
GGAAACCTCAAGCTGAGAAAGTTGATGTGATTGCCGGCTCCTCCAAGATGAAGGGCTTCTCGTCCTCAGAGTCGGAGAGCTCCAGTGAGTCCAGCTCCTCT
+
CCCFFFFFHGHHHJJGIIJJIHHJJJJDHGIIJJJJJJJJIIJJJJJIJJJIIIJJJJIJJIHHHFFFFDFCEDDDDBDDDDDDDCDCDCDDDDDDDDCDD
@3XU
CAACAAGCTCCCCGGCGAGAAGCTGGGCCGCGTGGTGCACATCATCCAGTCACGGGAGCCCTCCCTGAAGAATTCCAACCCCGACGAGATTGAAATCGACT
+
CCCFFFFFHHHHGJJJJIJIJIJJJJJJJIIJHFFFDEEEEDDDDDDDDDDDDDDBBDDDDDDDDDDDDDDDDDDDEDDDDDBDDDDDDDDDDDDDDDBDD
@3XV
TGAATGTGACAGCACCTACACCTCAGCAGTTACAAGCCTTCAAAAATGAAGTAGGAGTACTCAGGAAAACACGACATGTGAATATCCTACTCTTCATGGGC
+
@CCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJIJIJJIJJJJJJJJJEHIJIJHIJJJJIJJJJJJJJHGFFDEEEEEDEEFEEDDDDDDDEEDDDD
@3XW
ACAAATTCGAGCATCACCTTCTCCCCAGCCCTCTTCACAACCTCTCCAAATACACAGACAAACTCCAGAAAGCAAGAATGCTACTCCCACCAAAAGCATA
+
@CCFFFFFHHHHGGJIHIIIIGIIIIG?FHIJIGIIIIJIJGGIEGIIJJIJIGHGAAGGHIIIJHHHHHFFFFCCEECCC@CCACDDDDDDBDDCBCDD
@3XX
GCCAACACCTGGCAAGAGGGAGCATATATTAAAAGGTTTATGGGCCGTCGGCCTATTACAAAGTTCAAACCTTGAGATGTTGACAACTATGATGAAATTA
+
05;(-2(-2))22.=?2(.(394(::8)36<>>>.())<))0).((<-'5''-'.;1)6))).((..((-,(-(-,(,(,:;0;3(((++(28<::2((2
@3XY
ATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCC
+
?1;;=)=DFDB;1?EC<AHBGEB@?FEG9<????BG@C;FFBAF66=@;4(=?AE:A7);;>BCB;'9??/9?8B8??BBBAAB@>>((:::9981?8?@
@3XZ
AAAGAATCTCCTGTCTCTGCTGGAAATGATGCCTATGTTGACCTTGATCGTCAGCTGAAGAAAACTACAGAGGAACTAAATGAAGCTTTGTCAGCAAAGG
+
?=;:B==D8AD:?2AAEB><CEFCD<C<+AFC?9?9CE<?:?1:C?B?BDD;8@DBDIIIEEI;=88==AA@@DAD>?ADA;;A;;>>;@6>>;>-,>A<
@3Y0
GTCCTGTATAACCAATGGAAGAGGTGCAAACAGAAAACCAAGTCATACCAGTGCTGTCTCAATTGCAGGAAAAGAAACTCTTTCATCTGCTGCTAAAAG
+
1=7<<=@=72?<?72<@<A3?+<=ACBCBBAB>B<??B<3?507?A=?BBBBB4=9.=4>>BABB4>AAABBA)5>@@?>);@5;3>.65;=>?=;?99
@3Y1
CCTGTCTCCAGATCTCAGTAAGGTACGGAGTAACTGTCCAAAAGCCATGAAGAGATTAATGGCAGAGTGCCTCAAAAAGAAAAGAGATGAGAGACCACTCT
+
CCCFFFFFHHHHHJJJJJHJJJJFHJJJIJFGIJJJIJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJGGHIHHHHHHFFFEEEEDDDDDDDDDDDDDDDDD
@3Y2
CTCCTGTCTCTGCTGGAAATGATGCCTATGTTGACCTTGATCGTCAGCTGAAGAAAACTACAGAGGAACTAAATGAAGCTTTGTCAGCAAAGGAAGAAATT
+
CCCFFFFFHHHHHJJJJJJJJIJIJJJJJJJJJJJJJJJJJJJGHJJJJJIJJJJJJJJIIJJJJJGIIJJJJHHHHHHFFFFDFFEEEEEDDDDDDDDDD
@3Y3
GCAGAAGGTTGCTTCCCATTGCTAGAAAGTGGTGATTCCACACTGGGGTCTTCCAAAGAAACCCTTCCACCCACATGCCAAGGCAATCTCCTTATCATGGG
+
@CCDFFFFFHGHGJJJIJJJJJJJJIIIJAEGCEFGIJIIJJJJJJIJDDHHJJIJJJJJJJJIJJJJJHHGHFFEEEEEEDDDDDDDDDDDCDDDEEDDD
@3Y4
AAAAGTTTTGGTGAAGAATCAAAAATAATGGTGGAAGATAAAGTTTCTTTTGAAAATATGACTGTTGGAGAAGAAAGTAAGCAAGAACAGTTGATTTTGG
+
@@@FFDEFHHHDFGIIJJCHFHGFHIIEIIJHHIHGGIIJIJIFHCGGIEIEGIJIJGIIJJIIIGIGGGJJIIHFH=EH@CCF@CEEECCDDCCDCCDD
@3Y5
CTCCCCGGCAGTGCCCCCTCCCACCAAGGTTGTGGCCCCGCCCTCATCCAGCGACAGCAGCAGCGATAGCTCCTCGGACAGTGACAGTTCGACTGATGACT
+
@@@FDDDFHHFDHIIIBEFHHEEHIIIII@AGHIIGHIII@=DFFECEEC@CB?BDDDDDDBB@BDABDDCCDDCBB<B<?CDC3>A>CC?BD@BCCCD>@
@3Y6
TACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCT
+
CCCFFFFFHHHHHJJJJJJJJIJJJJJJJJJJJJJJIJJJJJJJJJAGIIJJHHHHHDEFFFEEEEEEEDDDDDDDDDDDDDDFDDDDDDDDDDDDBDDDD
@3Y7
CAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGC
+
BCCFDFFFHHHHHJJJJJJJJJJJIJIJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHHHHFFFFFFDDDDDDDDDEEEDDEDEDDDD
@3Y8
CCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTT
+
CCCFFFFFHHHHHJJJJJJJJJJJJIJJIJJJIJJJJJJJJJJJJJJJJJJJJJJJBFFFEEEDDDBDDDDDDDDDDDDDDCDDDDDDD>ACDEDDDDCD
@3Y9
CGAGACATCTACAGGGCGAGCTACTATAGAAAGGGAGGCTGTGCCATGCTGCCAGTTAAGTGGATGCCCCCAGAGGCCTTCATGGAAGGAATATTCACTTC
+
+=;=DD:DCDDDFD91+CD@<:DFF@DB??DG?8?BDF?EC@F;7@C7)=7C27.=?=77.7?3@?<>>='';5558<AB>5(::@@??@AABDD>B>@@A
@3YA
AGAATGATCTTCAAGAAAAATTTGCACAACTTGAAGCAGAGAATAGCATTCTTAAAGATGAAAAGAAAACCCTTGAAGACATGTTGAAAATACATACTCCT
+
@@@FFDDFFFHHFGEGFGIFCFGHHGI<ACFHIEEH<FICHEGGIIGIJIIIGGIDH?FF<CFFHHGIIIBGHGHHHHGFFC@@:6@CCCEECCDDCCCCC
@3YB
GAAGAAATGACTCTTCAAATCAATGAACTTCAAAAAGAAATTGAAATACTCAGACAAGAAGAAAAAGAAAAGGGTACACTTGAACAAGAAGTTCAAGAATT
+
@@CFFFFFHHHGHJIIIJIJIJIJJJJJJIHIIIJJIJJJJGGIJIIJIIJIIJJJIJIGGGIJJJIJIJJIHG=ADFFFFFCEEEEDDDC@CDDEDDDDD
@3YC
GTCCTACCCTCTGTCAGTGTCTCCCATGGAGAATAATCACTGCCCAGCGTCCTCCGAGTCCCACCCGAAGCCATCCAGCCCCCGGCAGGAGAGCACACGCG
+
??<DD?DDHHHHHDHBEHGDHHGIBHHHGAGHGIDHHGGGGECGHDGEH?BDEGAFFF;DHHDGEH89?8AAC@CBD@A@?@B59<9>988<?A:A?BDBD
@3YD
CTTAGAAGAGAAGAATACCATGTATATGCAGAATACTGTCAGTCTAGAGGAAGAGTTAAGAAAGGCCAACGCAGCGCGAAGTCAACTTGAAACCTACA
+
C@CFFEDFHFHHGIJEHIIIJIJGGGIJDIIJJHHIGGFHIIFHHCHEHIIEEGGHGHHBHGICHIGHJGGGGDB?CBDDD?ADDDDDDDDDDDDDCD
@3YE
GACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTG
+
C@@FFFFFHHFFFGIJJJJJJHJJJGIGGIIJJIJJJJIGGIIIJGGIGGGIGIHIIIIJIFFFDCDEDDDCDDDDBDDDCDDDDDDD0<ADCBDDDDD@C
@3YF
CACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCC
+
CCCFFFFFHHHHHJJIJJJJJGIJIJJIGJJIIJJJIJIJJIJJJJIJJJJJJJIJIJJJJJJJJIJJHHHHHHFFFFFECEEEDDDDCDDDDDBDDDDD
@3YG
AACAAGTTTCATTGAGATGTAGAGAGCTAGAAATCATTATTAACCACAACAGGGCAGAAAATGTACAGTCATGTGATACTCAAGTAAGCTCTTTATT
+
@@??DBDDHHFHHE4C@F>?CIHIIIIIGGEHHFGIIIIIGGCHIDHHEHIICB@FBBFHIGH@FEGEC=C=@EEA7?A>EH;;;;BBC@>AAE>CC
@3YH
GAAGAACTTCAGAAGAGAAATCATAAAGACAGCCAGTTCGAAACTGATATAGTACAACGAATGGAACAAGAAACACAAAGAAAGTTAGAACAACTCCGGGC
+
@BCFFFFFHHHHHIJIJJJJIJJJJJJJIGJJJJJJHIJJGIJJJJJJJIJJCIGIJJJJIGIJJJGIJGHHHGFFFFEDDEEDCCDCDDCDDDDDDDDDB
@3YI
CGTCCATGTACAAGTACCCTTCTGACATCTCCTACATGCCTTCCTACCATGCCCACCAGCAGAAGGAGAACTTTGTCCCTCCCCATCCATCCTCCATGCCT
+
;@?DDDADFFHHHEHHGCCDGIJCFDEHIGIGHAGEHHEBHGIIIEIEHG@EHGGGJIGIEHIIHG(.=@;AEF@==CHC>B?AE@@AC@CB>>>5>:>AC
@3YJ
CAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCC
+
@@@DDFFFGBHHHJJGIGJIIJJJJJIFIJJIIIEGIIIJ?FGHGGGHIJJIGGGGIJJGEHGHCEFFDEEDBDABCD>ACD@CACCDDCDDDDDCCDB>B
@3YK
GCAGAGAATAGCATTCTTAAAGATGAAAAGAAAACCCTTGAAGACATGTTGAAAATACATACTCCTGTTAGCCAAGAAGAAAGATTGATTTTCTTAGACTC
+
@<@DFBDEFDDFHEHAFGBEFD@?E@HHI>BGEGGGIIDF@FEGGGG@DGBGIGHGHIBEHGFHIIGIIGHGIIIEEHHHFDEFFECCDEEEDCCACCCCC
@3YL
CAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGG
+
@@@DFFFFHHHHHJGIIIJGIIIIJJJJJGIIIGIGIHEGGIJJJJIJJJIFIIGIGIJJIIJJJJJJHHHHHFFFFCEEEEEDDDDDCDDDDD@BDBCDD
@3YM
CCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGT
+
CC@FFFFFHHDFHGIBFGBGHHEHGGIGGGEGGCHGIIIGGIGGGIIHIIFIHEHFHHFEFFFFEEEEEDDDD;@CCCCBBABDDCDDDDDDCDDDDBBD:
@3YN
TTCTTCAGTATGCACAGACCTCTGATGGACAGCAGATACTTGTGCCCAGCAATCAGGTGGTCGTACAAACTGCATCAGGAGATATGCAAACATATC
+
@@@DDBDDDFHFFIIIEHIIIIIFGHDEHIIIBCGEFHGGCGHIIEGIGHIEEFHGI8BGBHHAHIAHGEEEFECD?B;@BD@@CCCEDD=;@ACC
@3YO
TTCTTATTCTGAACAAGGAGCACAAGACAGTCCGACTCATCTAGAGATGATGGAAAGTGAGTTGGCTGGGAAGCAGCATGAGATTGAAGAGCTAAACAG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJGH=CHIGIIIIIJHHHFFFFEEEEEEDDDDDDDDDDDDDDDDDD
@3YP
ATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCC
+
@@@DFDDFFFFHHIJJJIIGHHGIIJIIBIIIHIIHIAGGIIJIJJGGI55@GGEHHHBBDFDDBCDDDDACCDDDCDCBDCACCCCCDCDCCA@CDDD
@3YQ
CCATCCAGCACGCCAGTGTCCCCACTGCATCATGCATCTCCAAACTCAACTCATACACCGAAACCTGACCGGGCCTTCCCAGCTCACCTCCCTCCATCGC
+
CCCFFFFFHHHCFGIIGIJJJJJJJJJJJJJJJJJIJJJJJJJIJJJJJJJIJJGIIJJJJJHHHFFFFFCDDDBDDDDDDDDACDDDDDDDDDDDDDBD
@3YR
ATGTGTTATTGATGACTCCAATGAGCATATGCTTACTGCATGGGAAGGGCAGAGGAAAGCAAAAGGAGCAGAAATAAAGACAACAAATGAAGTTGTTTTGG
+
+:=2?2A,?74<=A4C,<=+<C7+7A+++2<7A4+**1**:7)?3*))8>AA1=A.=AABBBBBAA2=(()).)7;;7;33;3;(;2;;59999=399==;
@3YS
TCTTAAATGACCGCGTCTGGCTGGCCGTGGAGCCTTTCTGGGTTGGGGAGAGGAAAGGAAAGTGGAAAAAACCTGAGAACTTCCTGATCTCTCTCGCTGTG
+
CC@FFFFFHHGHHJJJJJJGIGIIJJIIHIJJIJJJJIJJIIHIJJJGEBBCDEEDDDADDDCCDDDDDDDDDDDDDDDDDDDCDDDDDEDDDDCDDBDDD
@3YT
AGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACT
+
@@@BDBDDFFDHBB@EFHHGEEEFDBDB?<CBFFHIADHGEHIHFGGDFHEHIED=7@DHEHEHEAEHE>DDD>CCC>CDACCABDDDA9?ACDDDDDB
@3YU
CGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCT
+
CCCFFFFFHHHHHJJJJJJJJJJJIJJJJJJGIIJJJJJHIJJJJJJJJIJJJIJIJJJJJJJJJJHHHHHHFFFFDDDDDDDDDDDDDDDDDDDDDDBDC
@3YV
CAGAAGGCTGTATGTTTGAAAAGGGCCCCAGGCAGTTTTATGATGACACCTGTGTTGTCCCAGAAAAATTCGATGGAGACATCAAACAAGAGCCAGGAATG
+
@@@DDDDDFHFFFG:EGG9FFB3A;FGFG=GGGHGHIIIIIIIC?BFHGGGI=FCFEHEHGGC?@EA>>?;?>B>A@>>?C>CCCCABBCC@??CBBBB:3
@3YW
AAAAATTCACCGCAGTGCATCAGAACCCTCCTTGAATCGGGCTGGTTTCCAAACAGAGGATTTTAGTCTATATGCTTGTGCTTCTCCAAAAACACCCATCC
+
BCCFFFFFHHHHHJJIJJJJJJJJJJIIIIJJJJJJJJJJJGJJJGIIJIJJJJGJIGHHHHFFFFCFEEDFEEEEEDBDCDDDDDDDDDDDDDDDDDDDB
@3YX
AAACTCCAGAAAGCAAGAATGCTACTCCCACCAAAAGCATAAAACGACCATCACCAGCTGAAAAGTCACATAATTCTTGGGAAAATTCAGATGATAGCCGT
+
CCCFFFFFHHHHHJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHHHFFFFFFFEEEEEEEDDDDDDDDDDDDDDFEDDDDB
@3YY
ACTTAGAGCAACTCAACCAAGTGAAAATGATAAACTTCAGAAAGAACTCAATGTACTTAAATCAGAACAGAATGATTTAAGGCTACAGATGGAAGCCCAAC
+
C@@FFFFDDHHHGGIIGIIIJHGIJHJIIEGIIJJJIIJHGGIHIIGHIIJJIFHGIIJIJJJJIGHIJIJJIHDHGIHHHHHHFFFFDCECEDEDDDDDD
@3YZ
CTTGAATCGGGCTGGTTTCCAAACAGAGGATTTTAGTCTATATGCTTGTGCTTCTCCAAAAACACCCATCCAGGCAGGGGGATATGGTGCGTTTCCTGTCC
+
CCCFFEFFDHHFHJJIIIIJJGIIJJJJJHIIJJEGFGGIJJJJJJJJGGIGGIIJIIJJJJGIIHHHFEFDFEDDDDDDD><CCDC:ACDBBDDDDD@CD
@3Z0
CTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGC
+
@@@?DDDAFFFDF<GHGGEE@FHD?EBFGGIIIGIIIIIEIGGGGEHGIGGIIECAGHGIIIGAEEFHHEDE;?@CCCCCDCCCC?BBBBC?CCB?AC:@
@3Z1
CCCGAAGCCATCCAGCCCCCGGCAGGAGAGCACACGCGTGATCCAGCTGATGCCCAGCCCCATCATGCACCCTCTGATCCTGAACCCCCGGCACTCCGTGG
+
CCCDFFDFFHHGHJIFIJJJEHIJIIIJJIJIJJJJIJEDFFFEECEDDDDDDDDDDDDDDBDDDDCDCDDD?BDCDEDDDCDDDDDDDDDDDDCDDB8?B
@3Z2
CAGGAGATATGCAAACATATCAGATCCGAACTACACCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATGACATCTCCTGTGACTCTCACCTCTCAGAC
+
@C@DDDFFHHHHGIIJJIHIHIJJJIJJGGEGEHGIJIJIGIIIJJJJJIJJJJJIIIJJEIJHHGCHIHHHGCEHCEFFCACEDEECCCCBDDDDDDDD
@3Z3
TGAAGAGATTAATGGCAGAGTGCCTCAAAAAGAAAAGAGATGAGAGACCACTCTTTCCCCAAATTCTCGCCTCTATTGAGCTGCTGGCCCGCTCATTGCC
+
CCCFFFFFHHHHHJJJJJJJHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHFFFEEEEEEEDDDDDDDDDDDDDDDEDDD
@3Z4
GAAAGACAAGAAGGAAAAGAAAAAAGAAAAGCACAAAAGGAAAGAGGAAGTGGAAGAGAATAAAAAAAGCAAAGCCAAGGAACCTCCTCCTAAAAAGACG
+
@<?DDDD8BBDCFGCGHHEGBCBGI@?DGDBDCB?FDHBH@?FHGGHFGG@F@EEGAE9CHHEDEDCB;?ACCCCBCC9<BC@BCCBCCC?ACCCCBBAB
@3Z5
CAGACCTCTGATGGACAGCAGATACTTGTGCCCAGCAATCAGGTGGTCGTACAAACTGCATCAGGAGATATGCAAACATATCAGATCCGAACTACACCTTC
+
CCCFFFFFHHHGHJJJJJJJJJJJJJJJGHIJJJJJJJJJJIJBGHHHIIJJJJJJIJJIIJJJIJHEHHHHFFFFFDEEEDEEDCDDDDDDDDDDCDDDD
@3Z6
CAGCCAATCTCTAAGTGTATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGCACCTTCCCAGTAGCATGGGTGTTTATGGGCAGG
+
;;;8>5))28.)).)2.).:)@8>)):9((.4=9>7(.<1))<39=(5==1(86;>8=;?1.=5'''(.7((((.643-:=(,8265(3'+8(8:/66(09
@3Z7
GTCAGCCAGGAGGGTCCTCCAGGCCTTCCGCCTCAGCCTCCACCACCAGTTGCTCAACTGGTCCCCATTGTGCCCCTGGAAAAAGCTTGGCCAGGGCCAC
+
@@@DDFFFFFHHGHEHHIIJIBGCHHIIGIJJIGGGGIIGJGIJJJJGICHIJIGCEHGHHHA@DFFEEECEDEDDBDDDDDDDDBCCCBDDDDDDDDDD
@3Z8
CATCACAATACTGGACCTCCCCCACGGGGGGAATCTATCCCAACCCCAACGTCCCCCGCCATCCTAACACCCACGTGCCTTCCCACTTAGGCAGCTACTAC
+
??1=:2=A?+22AEEI@:<<AFA@F:E0)'6&6=>8A(>++>3<075?0+<+<(02707&&8A?AA:<:A85>(5>?12:4>(+(2(+(:>A(((+(+((4
@3Z9
CATCAGAACGGAACTGCCTCCTGAGAAGCTCAAACTGGAGTGGGCATATGGTTATCGAGGAAAGGACTGTAGAGCTAATGTTTACCTTCTTCCGACCGGGG
+
CC@FFFFFHHHHHJJJJJIJJJJJJJJIJIJJJIGHIJGIEHIJJJJJIJJEGGGHIGIJIJHGHGFFF@DFEEEEDECDBDDDDDDDDDDDDDDDDDDDD
@3ZA
GGAGGAAAACCACTTCATCCACCGAGACATTGCTGCCAGAAACTGCCTCTTGACCTGTCCAGGCCCTGGAAGGGTGGCCAAGATTGGAGACTTCGGGATGG
+
8;?+4=AD>?DDAA+CC@@FFD:<<C@?D?DDI*0?B9*9BBB?B*3B)))/8).=3=@C>AAC?C2?<.)7('.58;9:5,(,(:?A932:A(29;>)80
@3ZB
CGACGAGATTGAAATCGACTTTGAGACCCTGAAGCCGTCCACACTGCGTGAGCTGGAGCGCTATGTCACCTCCTGTTTGCGGAAGACAAGGAAACCTCA
+
@C@FFFFFHHHHGIGGGIJIJJJIJIJJIIGIJIIIIIJJJJIJGHGHHIJHFGHHEFFDDDDDDEEACDCDDDDDDCDDBBBDDDDDDDDBDDDDDDC
@3ZC
GACAGCAACACGTTTGAAATGAATGGCAAAGCTCTCCTGCTGCTGACCAAAGAGGACTTTCGCTATCGATCTCCTCATTCAGGTGAGAGTCTGGACTCTTG
+
@@CFFFFDHFHFDCGGIBAEH>FGIIDHHEHIIGGIHCGHI@HHIIGGIBFHIGIBGHIGHDBHHGGHDBFDCCEEA@C>AAC@CAAA>:@A@CABCC>>>
@3ZD
CACGAGAGCTGATGGCACTAACACTGGGTTTCCAAGATATCCAAATGATAGTGTATATGCTAACTGGATGCTTTCACCCTCAGCGGCAAAATTAATGGAC
+
BCCFADFFGHHHGJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJIJJIJJFIIIJIJJJJJJJJJJJJJJJJHHHHHHFFFFDDDDDDDDDDDDEDDDD
@3ZE
GTGATGAGAACAGGAAAGCCTACAAATTTATTAAGGGAAGAAGAATTTGGTGTTGATGATTCTTATTCTGAACAAGGAGCACAAGACAGTCCGACTCATCT
+
@?@FFFFFDFHHDFFHGJFHBEEGEHIC<ACEHHAB>;:??FFIEHHGCGBF?D=BFI:C>AGGFHIAD;EDEHCHFAD==?@>AE;C?-5>?;BDDDC@C
@3ZF
CGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTAT
+
@C@DFFDFHHFDFIIJBBHEIGJFCFEHIGHIEHGIJJIJFIJIIGGIJIIHGII=BDFDF@BDCDBDDBBBCCDCCCCCCCDCD?CD:>ACDDCDDDCDD
@3ZG
GTCACTTCCTCCAGCTTCTTTGGAGCCGCATCACAATACTGGACCTCCCCCACGGGGGGAATCTACCCCAACCCCAACGTCCCCCGCCATCCTAACACCC
+
@<<DDDDFFAFHHGIGIHEIED9FEGGEGGACCHIGHDFHGGIIIEGHIGI@GBEBA?BB@BDDDDDDDBBDDD9????ABBBDB@DDB?CDACCD@CDB
@3ZH
CTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGC
+
CCCFFFFFGHHHHIJJJIJJJJJJJJJJIIJJJJGJJJJJJJJJJJJJIJJJJJJJJJJJIJJJJHHHHFFFEFFEEEECEEDDDDDDBDDDDDDDDDDD
@3ZI
GCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGT
+
?;1A4===C??CDA::+,:+,,<<CAB><FCEEI9ECBDEFECDDD?=BDD;D9C;3(=)877=@7@7ADA<?(6;6;3(55>:5>A>>??<9=5:>4+::
@3ZJ
GAAAAAGAAATAGAAATACTTATAGAGGAAAATGAGGACCTCAAACAACAATGTATTCAGCTAAATGAAGAGATTGAAAAGCAAAGGAACACTTTTTCATT
+
?7?A:A?1DCDFFIF9F<BHHAF@EAF@GE;?FEF@FFCFFFFIIF>BDFFF@BFFGFFEBEEGGII==C7=EAEC=AA=@9@@AB>AA??=ABBBBBBDE
@3ZK
GGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTT
+
@@@AD8D?CBFHHGGEHGFG<?CAAFGHDGDHEFFEHGIHGDADDFCCHGEDHGI8;EGGIF>EEEED:@;BCC>BB?BB?@BBBB@>>C@A@?B3908<
@3ZL
CCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTAT
+
CCCFFFEFHHHHHJJJJJJJJJJJJJJJJJIJJJIIJJJJJJJJIJJJJJJHHHFFFFFEEEEEDDDEDDDDDDDDDDDDDDDDDDEDDDDDDDDDDDDDD
@3ZM
TACAAGTACCCTTCTGACATCTCCTACATGCCTTCCTACCATGCCCACCAGCAGAAGGTGAACTTTGTCCCTCCCCATCCATCCTCCATGCCTGTCACTTC
+
<?<?DDABDD?A3C<E<++3<+A?<FCEE>ED>@EED@91*::*:BBB@8)0?D/?BC8=B@CCDI>)7.7).5;A>ADDDAA>>A>5(--5(;,5(:(:>
@3ZN
TATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCC
+
@@@DDDDDHB?FFIEDGGIIIGHGIGEHBFHGHIIGIIIIEHAHH@?@FHHEH>GAFHGGIIHEE?AEBCE@DDCCCC@CBBCCCCA?CCCCBBC;?<AAB
@3ZO
GGTAAGAGCATGCTGGTGCCCTGTAAAAACTTAATCCTTAAGAAATTTTCACATACTGGTTGTAGAAATTTATTATGGGAAAAAGGGGTGCCAAAAATATG
+
8((2>):@)9))2.)9).)..).2<8>88()).;.)21.=)>88).<)0.)))0))))).0<'9)))8))8=)8))8)().(.65/(',3(,,(,(,(,(7
@3ZP
GGGAGACTTCCGGGGGCCTCACTGCTCCTAGAGCCCTCTTCGCTGACTGCCAATATGAAGGAGGTACCTCTGTTCAGGCTACGTCACTTCCCTTGTGGGA
+
CCCFFFFFHHGGAIIGIGIJJJIJIIJJJGIIJIJJIJHHHFFEFDEEDEDDDDDDC@CCDDDD<ACDDDDCDDDEDDDDDDDDBBDCDCCADCD:ABDA
@3ZQ
GTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJHJJJJJFJJJJJIJJJIJJJJJJJHHHGHFFCDDDDDDDDEDEEEEEDDDDDDDDDDDDDD
@3ZR
CACTACCTGGGCCATACAGACTGTGTGAAATGCCTTGCTATACATCCTGACAAAATTAGGATTGCAACTGGACAGATAGCTGGCGTGGATAAAGATGGA
+
CC@FFFFFHHHHHIJJJJIGIIJJIFGGIJIJIJJJJJJIIJJJJJIIIJIJJJIJIHJJIIIIJJGIGIJHIHHFHHFFFFFDDBDDDDEDDDDDDDD
@3ZS
AAATAAAACAGTTAATGGGGACAGTCGAAGAACTTCAGAAGAGAAATCATAAAGACAGCCAGTTCGAAACTGATATAGTACAACGAATGGAACAAGAAAC
+
CCCFFFFFHHHHHJIJJJJJJJJJIJIJJJJJJJJJJJJJJIIJJJJIJJJJJGJIJJJJJJIJJJHHHHFFFFFFEEDFEEEDDDDDD>CCDDDDDDDD
@3ZT
TGCCAGTCAGATCGCCTCGGGTATGGTGTACCTGGCCTCCCAGCACTTTGTGCACCGAGACCTGGCCACCAGGAACTGCCTGGTTGGAGCGAATCTGCT
+
<@@BDDDB<=22<CBEFE?BBCFH>F11):??*1)B;3BF??@@F/?CAFHB@FEGEGGBH=@;;>A;?;?BB2?9@>((::95:(0>999-05<>>@>
@3ZU
AAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCAC
+
CCCFFFFFHHHHHJJJIIJJJJJIJJJJJJJHIIJJGIJJJJJJJIIJIJIIHGHFFFFDEEEEEEEDDDDDDDDDDDDDDDDDDDDDDDDDEDDDDDDDD
@3ZV
CACTCTTTCCCCAAATTCTCGCCTCTATTGAGCTGCTGGCCCGCTCATTGCCAAAAATTCACCGCAGTGCATCAGAACCCTCCTTGAATCGGGCTGGTTTC
+
@@@FFFFFHHHAFHIIJFEHGGHGIHIIGGAFC<CHGIJIHIGIEHIIJGIJJJGIIIEECEHEFDDAACDECC@CDDDDDDDDDDDDCABD@BDDDCCA@
@3ZW
AATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACT
+
CCCFFFFFHHHHGJJJJJIJJJJJJHIJJJJJJJJJJJJJIJJJJJJJIEGIHHHHHHFFFFFFEDEDDCCDDDDDDDDDDDDDDDDDDCDDDDDDDDDDD
@3ZX
AATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCC
+
?@7DDDDDFFDFHIIIIIICEFHIIIIIGFHHGIIIGAFDCGGHGEH<CGHCEHEDDEEDDCCCCCCBBBBBBB?@B@BCCCCCBCCCCCDCCCCBBCBB@
@3ZY
CACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCC
+
@@7?BBDD>FBDDEIIGGIGEGGGGGIGIDHGIGGHIIIIAHBHEEHEIIGIIIGHDGGIDE7.=CHEEEHHHFBCEEBCCCCCBBC>@ABB?BA?CBBB
@3ZZ
CTTTGTCAGATGAGCAATGGGATGTTATTAACTGGAGGAGGGAAAGACAGAAAAATAATTCTGTGGGATCATGATCTGAATCCTGAAAGAGAAATAGAGGT
+
??<:=22==2CD<:+2A<AAF<<?F<99+<92AEE?:CD;D?D;D;?99?)8.=BCE@78A@==C;5A)-6).?;7?A>366@A>355>(;9,5555,59,
@400
TATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTAC
+
@@CFFFFFHHGDFIHEHIGJHHHIIDHIIJIHHGHIIIGHIJJJJGGIEHHHIIIIFICFIIIJJIJJHHHFHFFFFFEDDDDDDDDDDDDDDDEEDDDDD
@401
CTCTGATGGACAGCAGATACTTGTGCCCAGCAATCAGGTGGTCGTACAAACTGCATCAGGAGATATGCAAACATATCAGATCCGAACTACACCTTCAGCT
+
@?;DBDDBF8FDD9;E>E@E@<HAEHGGG@;BE>BDAG:?F:?DFC;FGIGGEHBCFE>@FA;;CEH<>EEC@@;B;?B;.(6=B=><>@>9>CCAC@CC
@402
CTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACT
+
@@@DDFDFHHHHHIIIEIIGGAHHGGGIIIIIGIIEGHHGGEHIFIIIIIIIIIGHGGIIGHHEHHCEFFFECDDDDDDDCBBC@CCDDDDEDCDCCDDDD
@403
CTTTTCTCCATGGCCTTTCCAGATAATCAGCGTCCACTGCTGAAGACAGACATGGAACGTCACATCAACGAGGAGGACACAGTGCCTCTTTCTCACTTTG
+
@@@=BB=B?DDCD9E>B@@FEH?AE<F@HE>1:CEFHAD@D>9B?9BDG<?;DGGF88@=FCCD;;7)=BEDD8==?25?=;,:3@@CCCCCCCCCCCCC
@404
GAAAACACGACATGTGAATATCCTACTCTTCATGGGCTATTCCACAAAGCCACAACTGGCTATTGTTACCCAGTGGTGTGAGGGCTCCAGCTTGTATCACC
+
CCCFFFFFGHHDHJFGGGIIJHGIIGIJJJIJGI<HGGIGIIJIJJJIGHHIJJEHGGIJJJFIIGGEHHHHFFFF;AAC@CDD:ADDCCDDDDBDDDEDC
@405
CGACTACAACCCCAACTACTGCTTTGCTGGCAAGACCTCCTCCATCAGTGACCTGAAGGAGGTGCCGCGGAAAAACATCACCCTCATTCGGGGTCTGGGCC
+
@@<DFFFFHHHFHAHIIIHAAFHCHHIGGGHHEGHGIGEHBBGHIEHEFHIGIIHJGEIFGIIDFAE6A@@DDDBDBACDCCB??ACDDDBBB5>CDDDBD
@406
CTACAAGGGAAAGTGGCATGGTGATGTGGCAGTGAAAATGTTGAATGTGACAGCACCTACACCTCAGCAGTTACAAGCCTTCAAAAATGAAGTAGGAGTAC
+
@CCFFFFFGHGFHIIIIJHIICFFHJIIJJJJGIJJJJIIGIIHIIJDGIGGGGGIGEHGGIJIJGIHJJHHHHHGEFFFFFEEEEDDDCDCCDDDCC9?C
@407
TGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGC
+
CCCFFFFFHHHHHJJIIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJIJJJJJJJIJJJHHHHHHFFFFFFEEEEEDDDDDDDDDDDDDDDDDD
@408
GTAACTGTCCAAAAGCCATGAAGAGATTAATGGCAGAGTGCCTCAAAAAGAAAAGAGATGAGAGACCACTCTTTCCCCAAATTCTCGCCTCTATTGAGCTG
+
?=?ADDDD?FFDHIHHIIIIIGB?CBFHGGEDGCHHHG:DGH@BGHIIIG1BFD=B@HGE@=@FHIGIFEHEEFEEE=CCCCC@CCBBBBBCCCDCCCAC>
@409
GAAAAGTGCCTGTACAATGTCAGTGCCTATGATCAGAAGCCACAAGTGGGAATGAGGCCCTCCAACCCCCCCACACCATCCAGCACGCCAGTGTCCCCACT
+
CCCFFFDEBDFHDHGIBHIEHHIEDEEAHCDHEHGGHGGGHBGGIH?DHIGCBDEHJJGIIIGHIIJIIHFBDD<@BDCC?CDDDB9@B@BDCDDDDDCDD
@40A
CTTGATTAGAGACCAAGGATTTCGTGGTGATGGAGGATCAACCACAGGTTTGTCTGCTACCCCCCCTGCCTCATTACCTGGCTCACTAACTAACGTGAA
+
@@CFFDDFFDHFDIGGEHDGGGIIFGHAEBHGGEHIIJJJJJEIIHGIHGGHHCAHCGIEGIJFBDBDDDDDDDEEDCDDDDDDCDDDDDDCCDDDDDD
@40B
CACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACT
+
@CCFFEFFHHHHHJJJJJJJJJJJJJJJJJJJJIJJJJJJJIJJJJJJJJJJJJIJJJIIHHHHHHFFFFFFEEEDDDDDDDDDDDDCDDDEDE
@40C
CTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGGTACCCACCCCAAACTGGATCCT
+
1>7A++2+2?CB)?<<?=?@=?7:1:?A;BB35:0?B?99=>BBB39)=8)9>7(..77=;=A:(;(>5((.(6=;-((5,,559===5222;?(+(3(33
@40D
CCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGG
+
@C@FFDDDHHGFHIGGABCEFHIIEFHDHHCDGI<C:FHIEHGGGHIIBHDHHIGFHGBAFA@==?BDFCDCAC@DEE?8;;@9ABBB?BBBB:>CC:>>B
@40E
CTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACT
+
CCCFFFFFHHHHHJJJJJJGJIJJJJIJJJJJJIIJIJJJIJIIIJIJJJJIJIJIJIJJHHHHHHFFFFFFEDDCDDDDDDDDDDDDDEDEDDDDDDDDD
@40F
CTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAA
+
CC@FFFFFGHHGGEHIJGJJJJCHJJJJCGDGGIHHIJJIJJIJJIGGIJJJIGIGJFGHICHHHFBDCEECDDDDDDBDDBCACCCDDEDDD>CCCCDD
@40G
GTGGAGCCTTTCTGGGTTGGGGAGAGGAAAGGAAAGTGGAAAAAACCTGAGAACTTCCTGATCTCTCTCGCTGTGAGACATGTCTGAGACTCCTGCTCAGT
+
@BCFFFFFHHHHHJJJFHIJJJFHFHHGIJJJIIIJGHJIJIIJJJJJJJHHHHHHFFFFFFDEEEDDDDDDDBDEDDDDDDEDEDDDDDDDDDDDDDDDC
@40H
GGAGGATCAACCACAGGTTTGTCTGCTACCCCCCCTGCCTCATTACCTGGCTCACTAACTAACGTGAAAGCCTTACAGAAATCTCCAGGACCTCAGCG
+
@@@DDD?DFDHFHGDHG<EFGGF<E>HGIGGEBE>GGGADGIIGIIBEGIF<A>>CDE@BDCAA>?=@ACCBA@(,:@ACCCCCA@C>9?BBCCCC><
@40I
AGAGCCAGTAAGAACTAGGGAGGGGCGGGGGACGGTGCCAAAGCATGAGACCGGGTGGGCACCAGAGGCTGAGAGAGGGGGAGCAGGAGGAGGGCGGGGGG
+
(00(((2(3))2))))2))()(-((((.''&&&&&)(&((((+((+((((+()-70557(5((+((((((((((4(+()&)&)&(+((+&+8&&&&&))50
@40J
GGAGATTGAAAATCTTCCTGCCTTCCCTCGGGNNNNNNNNNNNNNGCGTCTNNTNNNNNNNNNNNNNNNNNNNNNNNANNTGTATGAAGGAACAGCAGTGG
+
=;;;A+=AB:A<DEEEECBF@E9F3?FFEF?D#############00-<;@##-#######################,##,,++<AA<:>8988<<<>A>A
@40K
CCGCTATTACTATGAGAAAGGAATTATGCAAAAGGTGGCTGGAGAGAGATATGTCTACAAGTTTGTGTGTGATCCAGAAGCCCTTTTCTCCATGGCCTTTC
+
CCCFFFFFHHGHHJJJJJJJJIJJJJJJIJJJJJJGHIGIIJJJJJJJGIIJJJJJJJJIIHHIIHIGHEHHHHHFFFFFDEDEEDDCDDDDDDDDDDDDD
@40L
CCTCTCTCAGCCCCAGCAGAACAAACCAAAGAAAAAGGAGAAAGACAAGAAGGAAAAGAAAAAAGAAAAGCACAAAAGGAAAGAGGAAGTGGAAGAGAAT
+
CCCFFFFFHHHHHJGJJIJJJJJJJJJJJJJIJJIGJJIIIHGIIJJIIIGIJEHIIJIHEHHEDDEEDDBCDDDDDDD?CCBCCD??B:@CDDDDDDDC
@40M
GGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCA
+
(-3@?@)8)=>?<><<()2@1=>84.8>@?1@3@??9<>??;??89=<=31=18>8=>??15>?@8))=;9;;;??<=;;>;=:77;'7;;575&)2//:
@40N
GTTTTGGCTGTGGAGTTTCACCCAACAGATGCAAATACCATAATTACATGCGGTAAATCTCATATTTTCTTCTGGACCTGGAGCGGCAATTCACTAACA
+
C@@FFFDDHHHHHHGEHIIIIJJIJJJJJJJJJJJIJJJIJJJJJGJJJJIJIAGIJIJJJJJIGGHJIHHHHGHEEEDEBCEEDDDDDDDCDCDDDCC
@40O
CCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCT
+
?@@FDBDDHFHA?G<EAGHEB;EHEFHDGEIIIGEEC:FGHGFGHIIIHGHGFFFFFFFCD@CA;AB=?B?BCCCCCC>CCBBCBBBBBCCCCC::>CCBC
@40P
GTCCGGAATGCCCAACGACCCAAGCCCCCTGCAAGTGGCTGTGAAGACGCTGCCTGAAGTGTGCTCTGAACAGGACGAACTGGATTTCCTCATGGAAGCCC
+
?=8BBD:@A<FHDHB?FBC<CGHC@GDHA:68?9?/9=;=B(=.8.=='>EHB?;;ACA(6.;ACCCA>@(,,(<@=0002+3?4:>4>(+>>4:C@((8?
@40Q
CCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCC
+
@CCADEFDHHHHHIGHGGIIHIGIHIJJGIEHHIGGJIGIIIIDF8DBFHIGCHIEH=EIIEFEFD@?DEEEDDDBDCC@CDDDDDDDDDDBD@CCDDD@C
@40R
CCCTTCCGCACCCGCCTCGGACTCTATTGGGCCCCAAATTCTCACCAGTCCGTCTCCTTCAAAATCCATTCCAATTCCACAGCCCTTCCGACCAGCAGATG
+
@CCFFFFFGFFHGIAGHIIIBFGIIJJJFJJJJJJGJIEECCHHIGIGGHEHHEDDFFFEEEEECCDDDEDDEDDDDDECCBABDDCCDD>@BDD@DD@CC
@40S
TGCATCTACAAACTAAACTCATACACCGAAACCTGACCGGGCCTTCCCAGCTCACCTCCCTCCATCGCAGTCCATACCAGATAGCAGATACCCCATGGACC
+
;(;(:).)<.)22;.:))846=<><<?8??2(..:=:6==?8==>83=>??:7)8(66(,).,(9(9<<5,8,,,;;75;(+(++63(+6;::85(28<55
@40T
CCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGT
+
@@CFDEABHHHDDGIGIGAHIHIGCGIIIJIIBGGGGCEGHIIIJIGEHGAFHIGHGHGIGEGCHEFBCDCCCDDCCDDDDACCCDCC?@?CCDBCDDABC
@40U
CAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCC
+
CCCFFFDFHHHGHIJJIIIGGJGIJJJJJJJIJJJIJJJJJJJJIJGHJFIEIGIJIEIGHHGHHDFFFEEDDDDDCDC>CDEDD@CCCDCCDDCDDDBDD
@40V
TTTTAGTCTATATGCTTGTGCTTCTCCAAAAACACCCATCCAGGCAGGGGGATATGGAGAATTTGCAGCCTTCAAGTAGCCACCATCATGGCAGCATCTGC
+
@@CFFFDDHHGHHIIIHGGFHJIIIIJJJJIIJGIGHIJIGGHEIGIJIDE8AEEFFEHEDFFFFFEECDDDCDD>;ACDCDDBB>?ACCDDCDDDDDDCD
@40W
CCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTAT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJGGJJJJJJJJJJJJJJIHHHFFFFFEEEEEDDDEDDDCDDDDDDDDDDDDDDEDDDDDDDDDDDDDD
@40X
CAGCGTCCACTGCTGAAGACAGACATGGAACGTCACATCAACGAGGAGGACACAGTGCCTCTTTCTCACTTGATGAGAGCATGGCCTACATGCCGGAAGGG
+
CCCFFFFFHGHHGJJJJJIJJJJJJJIGIJJIGIJJIJJJJJJIIJIJJJJJIIJIIJHGGHHFFFFFFFEECEEEDDDBDDDDDDDDDDDDDDDDDDDDD
@40Y
TATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTAC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJGIJJJJJJAHIJJJJJJJJJJJJJJIJJJJJJJJJJJHHHHHFFFFFEEDDDDDDDDDDDDDDE;ACDDD
@40Z
CCTGTACAATGTCAGTACCTATGATCAGAAGCCACAAGTGGGAATGAGGCCCTCCAACCCCCCCACACCATCCAGCACGCCAGTGTCCCCACTGCATCATG
+
<@<D;?ADF<F?DBD<,<CHF4CEACEFHCFBFFEFFI?CFBEFEBDFEB?@D;DFE9@FFEEB>?BBBBBBB@AAB@B5?@B:>A@ABBB<BB@BBBBBB
@410
ACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGT
+
@@@FFFFFHHHHHJJJJJIJJJJJJJJJJJIJJIJJJJJJJJIJJJIJIJIJJJJJJIJJGGHGGHGFFFFFFDDDDDDDDDDDDDDDDDDDDDDDDD9@B
@411
GTTGACATCATGGAATGGCTGGTGGGGACTCACTTGGCCACTGGGGAGTCAGATGGAAAACAAGAGGAAGAAGGGCAGCAGCAGGAGGAGGAAGGGAT
+
?@@DDDADFFHHBGGI@GHIFBHIG<:DDDD9?9D9<?@;DFGIJGFFC;;CCGGICEHE);?@32?;@ABC35;<5,8??958<029(+928ABD19
@412
ATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCA
+
@@@FFFFFHHHHGHIIIDGGIIFIGJJJJIGIAHIIJGHIJJJJJFIJJCEHIJJJIJJJJJJJJHGHFFDDEDDDDDDCDDDDDBCBCDCDDEDDD>CC
@413
CCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTTATGGGCAGGAGT
+
@@@DBBD?FFHBA?<EFH@<CHGGG@E?FHGBDEG@HG9CFH@GEA?=B8B=F@FG@C@GGHBDB??6=?BBBBBC>C>C;@BB(0)<?@@:A@?959BB(
@414
CTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTAT
+
CCCFFFFFHHHHHJJJIJJJJJJJJJJJJJJJJIJJJJJJJGHJIIIIJJJHCEHHHEFFFFFEEEEDDDDDDDDDDDEDDDDDDDDDDDDDDDDDDDDDC
@415
CCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGG
+
C@CFFFD>CFHHFI>FGDGIGHHIHIIIEEGGGIEEGE:DDCCFGEHFHGEEE>=EEFFF@CEECECCBCC5>CCCCCCCECCDCCCCCBCACCCCCCC
@416
GAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTG
+
@<<DBDBDF?ADFEFFGGEIGIGIGICGHIIFECEGI3B?DFFEHII>FFHGIIIEHGEEGHHFHEEEEEBEB2;??ABDD?CCDEEDDC:8<>DDBDBCC
@417
AGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCC
+
CCCFFFFFHHHHHJIJJJJJJIJJJJJIIJJJJJJJJJJIGFHIIJJIIJJJIIIJJJGIJJJJJHHHGFFFDDDCDDDDDEDEEEEEDDDBDDDDDDDDD
@418
CAAACTTATAGATATTGCACGACAGACTGCACAGGGCATGGATTACTTACACGCCAAGTCAATCATCCACAGAGACCTCAAGAGTAATAATATATTTCTTC
+
?:8B:DD;?:=2<2A<<E<AA1<@F?<1:CEB*:D???DBB<909*9??DBBCD@;AC@===7=ADDD).76@;;@?AA355>=::(5,55>5;;5>;A>:
@419
GAGACATCAAACAAGAGCCAGGAATGTATCGGGAAGGACCCACATACCAACGGCGAGGATCACTTCAGCTCTGGCAGTTTTTGGTAGCTCTTCTGGATGAC
+
??;?DDDDB<?+A:?@?CFGFIECFDCD?EFACCG?;??FEDBF<FFAFF5;B6B<?@BAA9?BBBBBA(>ABBB9?34(42<B?>A:>>AAB>BBBBB(>
@41A
GTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTAC
+
@:?DDDDDFFB>?E<A<AF@GG@HE@ABGC@FGGFIFEDGEFECFDF9C@FFFF@7@77=CEEAECEA?;;;@@B;A>A?;;>8??9??B?<?8<AA+:@:
@41B
GGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTT
+
@@?DDFFFFGFFHICHJJJGFHIJJJGGGFHJJIJJJIJJJJJJJJJJJIJJJJJIJJJGGIJIJIGHHHGHFFCBFDC>@BBDDEDDDDEDEDDDDCDCD
@41C
TTGGCCTCTAAACTTAGCCTCTCACCAAGGGAGCATCCCCTCAGTCCTCACCATGCCTCAGGAGGTCAGGGCAGCCAGAGAGCATCCCACCTGCTCCC
+
8??1BDDDFFDHFGIIFGCHIIFGCHGGIIB=?AGGIGGIEH@;9?FFGGIIGEHCHCGHGGEEG5=?EDEE=<BC?BBB?<@CCCCB>?B?CBCCAB
@41D
CCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGCAGGCATATGGGCAACAAAGC
+
CCCFFFFFHHHHGJJJJJJJJJJJJJJJJIIJIIFHIGIJIJIJJJIIIJIHHHFFFFFEEDDDDDDDDDDDDDDDDDBDDCDDBDDDCDDDDDDDDDDDC
@41E
CACCTGCTCCCTGCTGGAGCAAAAGGCCCCAGCAAACTTCCATATCCTGTTGCCAAGTCTGGGAAGCGAGCTCTAGCTGGAGGTCCAGCCCCTACTGAAA
+
@@?AAD:BBF;<FBEB<F?FE9;E;GGB@EHCGBH9DHHD<B9FGFHI9F@E>GB@@C47@FEICGEB14936(65;;AC;<@BC@>C>885?B<C:3:>
@41F
CCAAAGTTGGTGTAAGAGCCGGCTAACACCTTAGGGGAGGTGAAGATTATAGATTTGGGGGAAAGTGGACAGACTGTATGGGGAGGATTAGAAAGAATTA
+
000(-)2)2)(((.).)).3((((()2))(20)))(-(0'-(.)).)).)8)))))))-'','(((((((,7(,((((((+(((&)((+(4(((+(+(((
@41G
ATGCAGGATGCCACCAAGCATGGCAACATGACAGAGGACCATGTGATGCACCTGCTCCAGAATGCTGACCCCCTGAAGGTGTACCCGCCACTGAAGGGG
+
+==AAA3A<ABB<AB+2=+<++?=AA9AAAB>3A*1)):057=*0**9??7=A>B)=)=>)8;>>).7=32==@(.(>(-;(5;;587'''+83+88&&
@41H
TGGAACGTCACATCAACGAGGAGGACACAGTGCCTCTTTCTCACTTTGATGAGAGCATGGCCTACATGCCGGAAGGGGGCTGCTGCAACCCCCACCCCTAC
+
CCCFFFDDD?DFHIGIIB=AAGEHFIIIIGHIIIIIIIIIHIIIIHGEDHCGGIIGIGGGGIEHHHHGHFFC<>@BBCCBBBCCCCCCCBBCBC>BBBB@B
@41I
CTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTAT
+
@@@D?BDDHFF<FHAE=CAEDFEGGIEAFCGDD?B>9B;FE-;CCCAGGGHE===AEEE;7))66>CC==5;ACCC@@>>C@CCBBBBBB0??@@CBB?C@
@41J
CAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGAC
+
CCCFDFFFGHHFGJJJJJJHHGIJIIIJJJJIJJJJJJJJJJJJJIJJJJIHFHHHHFFCFDDDDDDDCCCDDDDDDDDDDDDDDDDDDDDDDDDDDCD
@41K
CGGGACTCGAGTGATGATTGGGAGATTCCTGATGGGCAGATTACAGTGGGACAAAGAATTGGATCTGGATCATTTGGAACAGTCTACAAGGGAAAGTGGC
+
;@;14@;?CCF<+<AEGD?A:C=?F>EFGFEDFF<?8BAG<BBB<B8B92.BCEFICF:777==D?>CEEEB??;?>>>>A9(-((->@A?B5(<?,5:2
@41L
CTGGACAGTGACCTTATTCAAACATCAACAACAGGGACCAGATAATTTTTATGGTGGGACGAGGATACCTGTCTCCAGATCTCAGGAAGGTACGGAGTAAC
+
<??DDBDD<+2<:?E>EE?F>@EC:EB<<<;EEDDIIDDCDDCCAADC9B;?B>/8BAC=A4=A8);@AAA;.365>>(55;>AA(:==?(3>5><929>+
@41M
CCCGAAGCCATCCAGCCCCCGGCAGGAGAGCACACGCGTGATCCAGCTGATGCCCAGCCCCATCATGCACCCTCTGATCCTGAACCCCCGGCACTCCGTGG
+
CCCFFFDFHHHHHJJJJJJJJJJJJJJJJJJJJJJJIJHFFFFEEEEEEDDDDDDDDDDDDDDDDDDDDDDDDDDDDEDDDDDDDDDDDDDDDDDDDDABD
@41N
CAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATAT
+
@CCFFFDFHHHHHIIJIDIEIGIJG@GEHIHIIHGJGIJGIIIIDB?FGHIJJJJJGJJJEIGIGFHHFFFFDFEEEEDDCDDCDBDDDDDC>>ACCCD
@41O
GCATTTATAAGCCCAGAGATGAAGCAAACAACGGGGGAGGCATAAATGAAAGCTTTGAAGGTGAAGATGGCGATGTGATTTGTTTGAATTCAGATGACATT
+
:+=17<?@CC<+2<A3723+<ACCAA7A+A5:)0)?'=4'(-=;;>;7);;6>>;;5;>>3>;55:=>59==5&)8+4:?;??==3+88(+++3+:83:?8
@41P
CCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGG
+
CCCFFFFFHHFHHIJIIIJJJJJJJJJJIJGHGIJJJJIGIIJJJJIJJJJJJJJJJJJIJJJHHHFFFFFFEEEEEEDBDDDDDDDBDDDDDCCDDDEDD
@41Q
CACACTGCGTGAGCTGGAGCGCTATGTCACCTCCTGTTTGCGGAAGAAAAGGAAACCTCAAGCTGAGAAAGTTGATGTGATTGCCGGCTCCTCCAAGATG
+
@?@DFDADFHHGGIGHGGGEHIIIEGCGGHIGIIEIGHIIIEGGIIGIGIIIFCHFFDFFFCEEC@CDDCC;@@CC@>AADDD@>@BD9B<??CCDC<AC
@41R
GAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCC
+
CCCFFFFFFHHHHJIJIJIIJJIJJJJHGEHJIIIJJJJJIJJJGGIEHIIIHHHHHHEFFFFEEACEEEDDCCDCDEDDDDDDD>ACDDDDDBDDDDDDD
@41S
CACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACC
+
CCCFFFBDFFHHHIJJIJJIJIJJEEGHIGGHCHHIGGGGHGEHGGHEGDDDGIIICCHGIIGGIJEHFGEEFEDDD?BBBDDDC>C>CDEEDDDDDDDDD
@41T
GGCAAAAGATATGCTTACAAATTTGACTTCCACGGCATTGCCCAGGCTCTGCAGCCACATCCGACCGAGTCGTCCATGTACAAGAACCCTTCTGACATCTC
+
;8+AD?;DD>A<A4A<B?<FF?EEFII<4AEE<8888:B<?9?D@D;/8BBB88C;;ACC>D;5:4>88>?',,58B>>5(;4>(9><>2>?A:(:4:4>A
@41U
CAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCAC
+
CC@FDDBDFFHGFIGIIHIIIJJJJJDGHIHIJJIGGIGIIJJJGIIIIJDCHGHGHHCCFFFFFED@A@;@CDCABD?<BBDDDDDBCCDDDDDDBDDDD
@41V
TGGCAACATGACAGAGGACCATGTGATGCACCTGCTCCAGAATGCTGACCCCCTGAAGGTGTACCCGCCACTGAAGGGGAGCTTCCCGGAGAACCTGAGAC
+
:=?14BADDB<:DB3++23A:CD9F?FDE9BCEICBCDEDDCEIDBDEDD8BDAB3AA@DDI@DAEDAD<=>A((;A???=8?AAA?>>0;>>A><<3<>>
@41W
GTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCC
+
@BBFDFBDHHGHGIJIIJHJIIGGHIIJIJIGHJIGIJJIJJJIJJJIHFGHHGGFFFFFFECDEDDDDCDBDDDBBDDDDDCCCCCCEDDDDDDDCDD
@41X
GCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGC
+
CCCFFFFFHHHHGJFIJIJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJIIGIJJIJJJJJJJJGHHHGHHFFFFEEEEEEEEDDDDDDDDDDDDDDDCBB
@41Y
TGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACC
+
?;@;DDAD?ADFHIIIIICHG>BCHHGBGEB>H?8??FHGB@==;FCGIIIGHFH>;ACCEECCCC3@CCDCA@C>CCDCAC@C?85>CCCC@@??B<>CC
@41Z
TAATGAATGTGGCAATAAATGAACTGAATATAAAATTGCAAGATACTAACTCTCAAAAGGAAAAACTCAAGGAAGAACTAGGACTAATTTTAGAAGAAA
+
@@@DDDD>?ACFDGIEGIHIIGHIEEHGAFGGEIIIIIEIIIIGHI<?FHGDBGDGBFFGHHIIIGDGGHGIGHGGEHFFHDF@DE@CD@>BECDAACA
@420
GTGATTGCCGGCTCCTCCAAGATGAAGGGCTTCTCGTCCTCAGAGTCGGAGAGCTCCAGTGAGTCCAGCTCCTCTGACAGCGAAGACTCCGAAACAG
+
B@@FFFFFHHHHAGIIHGIIJIIJJJJJJJJJJJJIJIJIJJJJJFHIJJIGHHFHFFFDFCECEEEECDDDDDDDDDDDDDDDDDDDDDDDDDDDD
@421
GAAAGTGGCATGGTGATGTGGCAGTGAAAATGTTGAATGTGACAGCACCTACACCTCAGCAGTTACAAGCCTTCAAAAATGAAGTAGGAGTACTCAGGAA
+
@@@FDDDFHHHHHGHIIIHIJHIJHICIIJIIGGGGIJIEEFGHHFIGIIJIGIIIIJEGIJBGHGIJGJJJJCHHHHHEFEFFACEEDE;?CDDDDDDD
@422
TTTAAATTCAGCTATGGAGAAAAGTGCCTGTACAATGTCAGTGCCTATGATCAGAAGCCACAAGTGGGAATGAGGCCCTCCAACCCCCCCACACCATCC
+
@@CFDFFFHDHGGIIIJGIGGIJIHGHGHGEHIJGGIJJJEGHIIIJGGIIIJIIJJJJJIHIJBCHHACFIGAGHHGHGFFFFDDDDDDDDDDDACDD
@423
CAGACAAACTCCAGAAAGCAAGAATGCTACTCCCACCAAAAGCATAAAACGACCATCACCAGCTGAAAAGTCACATAATTCTTGGGAAAATTCAGATGAT
+
@@@FDDFDFFHFHIGJIIIJIGIGFGIHEHIJIJGJJJJJJIJFIGHGGIBGH@GCEEGGGEFCCDFFDF;;@@>@CECD>CDDCDBCDCA@CCCDDDCC
@424
GGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGC
+
BC@DFFFFHHHHHJJJJHJJIJJJJJJJJJJJJJJJJJJJJIIJJIIJJJGHIIJIJHHFFFDDDDDDDDDDDDDDDDDDDDDDDDDDDDBDDDDDDEDDD
@425
GACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACAC
+
@C@DDF?BCFHG?GHGIEHIIIIIGI?AEHGB<@??DGCHGHIIA@BB?8?AHGIIIFGC@FGI@G@EEEHHE>BDCFCCEC2>C?CCCCCDCCCACCC
@426
ATTACAGTTAATGAAGATCAGATAAAGTTAATGAATGTGGCAATAAATGAACTGAATATAAAATTGCAAGATACTAACTCTCAAAAGGAAAAACTCAAGG
+
????DD?ADDAAA<EE4233<CFC<FEFCFID@EF<::CE)?DECEDD<<@DBDAED>@D>DEB<<C8B==<A)7@;@77=ADACCA(?@DD@@>A(>>A
@427
CCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATG
+
CCCFFFFFHGHGHJEGIJJJJIJJJIJJJJJFHECHIJJIJJIJJJJIIIIIJIIJIGJIFGIEHHFFFFDDEEEEEEDDDDDDDDDDDDDD<?CDDDDEC
@428
GTCATCATCAACCAAGAAGGAGAATATATTAAAATGTTTATGCGCGGTCGGCCAATTACCATGTTCATTCCTTCCGATGTTGACAACTATGATGACATC
+
CBCFFFFFHHHHHJJJGIIJHIHIJJIIJJJJJJJJIJIIIJJJIJJGIJIJIHGGHFFFFFCDEEEEFEEDDDDDDDBBCCCDDDDDDDCDEDEDDDD
@429
CTTCACTACTCAATCTGATGTGTGGTCTTTTGGAATTCTGATTTGGGAGATTTTAACTCTTGGTCATCAGCCTTATCCAGCTCATTCCAACCTTGATGTGT
+
9;((@;>=@@<=91;<;8@=))38;>8@@==??).<:>?<1:<>:127=(33=?>;??>3=>9)8=;69=>9??0>?@@@;).;;??==3==9<:<;=:;6
@42A
TGGAGGACGAGGAGAGACAGAAGAAGCTGGAGGCCGGCAAAGCCAAGCTTGCCCAGTTTCGACAAAGAAAAGCTCAGTCGGATGGGCAGAGTCCTTCCA
+
BCCDFFFFHHHHFJHIIIJJJJJJJJJJJJJJJJJJJJJJJJJHHHHFFFFFEEEDCEEEDDDDDDDDDDDDDDDDDCDDDDDDDDDDDDDCDDDDDDD
@42B
CCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCT
+
;@?BDDD;FBDFFGGHIAFFE@CF?EBHEBFHEBFH??FHGFDACHG?DABFACH;FB@C=@CCEH?>E>:BBD@;;;>>>>CCAB=?CCB>AA?BCA?C
@42C
CAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCC
+
@@<=D?DDFDDFAHGII@FGIIGIGIIGHGFEHIIIFIHGGHEGHIFC?FGEHHD>A>HBDF@DFEEECECCFCACCCACCCBBCC<BBCCCCCCBBBC
@42D
GTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACC
+
CBCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJHHHHHFFFFFFFEEEEEEDDDDDDDDDDDDDDDDDD
@42E
CATCTCCTGTGACTCTCACCTCTCAGACAACTAAGACAGATGACCCCCAATTGAAAAGAGAAATAAGGTTAATGAAAAACAGAGAAGCTGCTCGAGAATGT
+
CCCFFFFFHFHHHJJJJJJJJJJJJJIGJJJJJJJIJJIJIJJJJIJJJIHIJJJJJJGHFGIGIJJIHHHHHHHFFFFDDEEDDDDDDDCDDDDDDDDDC
@42F
GATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCC
+
CCCFFFFFHHHHHJJJJJJJJIJJJJJIJJJJJHGIIJJJJJJJJJIGHJJJIJJJJJJJJHHHHHHFFFFDFFEEDDEDDDDDDDDCDDDDDDDDDDDDD
@42G
CTACGCTTCGGGCATGCTAAATTTTACCTGACACGGAAGCTCACTGCGAAGGGAGATAAATGGAGCTTCGGGGCGGTCCTAAGAGGGATCCTGACGTATGG
+
-((23==(--((0()()2)).)))..:)83))):((7=?(.)9)..)-''''-.',))).(.((67;>>;''3&)&80&(((+(+(0-65(++2(&+2+(2
@42H
GGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGC
+
@@@DFFAFHHHGHJFIJJJJJIIIGEFHGGHJJJGEHJIJJIGIGIGJGHIDIIIIIJIJJIFFGHHFFFECECEECCCDCDEDDDDCDDDDDDDCDDD
@42I
CCTGACACAGAAGCTCTTTCCTGTTTTCTTATCCCAGTGCTTCGTTCCCTGGCCCGGCTGAAGCCCACTATGACCCTGGAGGAGGGACTGCCATTGGCTGT
+
@@@D?DDFFDHHFIBGIEIHHCHABEGIJGIIJJGHG@BEGHIJBFHGIED2DFHIEEEGGCHHHFBBBD>;ACEE?C?BA?BBB?B?8ACDC@@CCCCB8
@42J
CTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGAC
+
C@CFFFFFFHHHHIJGGJIJIJJJGEIJJIGIEIIJIJJIJJIIJJJJJIIJIJIGIGIIJJIJJHHFHDFFCDECEEECEEDDDDDDBDCCCD
@42K
GGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTAC
+
@@CFFF=DF?DDDHGBF<FHGIGGHIIIGIGI@DCHGGHGIEBGCGGCHGIBHICHEHEEE>BDDCA@AACDDDC??:ACDD@CDCCE=:AA?<ACDDCCC
@42L
ATTTCATATACACCTCTAGGGAGCCCAGTGCCGAGATACGCTTACTCGACGACACTTCATGTTCCAGTGCCTCGAGCGCTCAGGAAGGAAGAAGACTCGAT
+
8;9@5)@<)@).).6()):)8)38(-229).35((((0)0(7((../(('5'5/90..(.==1(-39=((-:('3;7&&8592(+(+67((+((536/22(
@42M
CCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGC
+
CCCFFFDDHFFHFIHIIJJJJJJJJJJJJJIJJIIJJGIJIJJJJIJJJJIJJJIIIJJJJJJJJHHHHHHFFFFFFDEEDDDDDDDDDEEDDDEDEDCDD
@42N
GGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCC
+
@CCFFFDFGHHHHHIIJJJIJJJJIJIJJIIJIHJJJFHIHIIIJIJIJJJJIJJIIIJIIJIJJGHFHHFFFFDCEDEDDDDDCDCDDDDDDDDDDDDDD
@42O
CCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJIJJJJJJIJHJJJJJJJJJJIJJJJIJIIJJJJJJIJHHHFFDDDDCDDEDEEFEEDBDDDDDDDDDDDDBDC
@42P
CCGAACTACACCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATGACATCTCCTGTGACTCTCACCTCTCAGACAACTAAGACAGATGACCCCCAATTG
+
<;?D;D??CFDCFGHIEE>AGFHIC?FHDEBEH@FGCH??DFA?FGDFHDH@DHEBHGBECBFG@F=;@;D@=?AEH?@;;>CC@C@6>;>>?@;;?CC>
@42Q
GCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACA
+
@CCFFDDDHFFHHJJJJIGGGJJJIIGIIGIIJJJJJGGIJJJGHJFIJJIIIIHHFHFFFFCECEEEDDDDDED@BCDDDC@CCDDCCDDDDDD9@BDD
@42R
CGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCT
+
>7=<A<+2+@>@<CBBA<>;<+3<7CB<<7@1?7A?:A>BB=:?B==*05A>:(..8.)8AABA5A=AA7>=;>5=695==;>>9=335,,5=9:<83+9;
@42S
ACCAGATAGCAGCTACCCCATGGACCACAGATTTCGCCGCCAGCTTTCTGAACCCTGTAACTCCTTTCCTCCTTTGCCGACGATGCCAAGGGAAGGACGTC
+
CCCFFFFFHHHHHJJGJIJJJJJGJIIIIIJJJJJJJJJJJIIJJJJIJJJJJJJHHHHHHFFFFFFEEEEEDDDDDDDDDDDDDDDDDDDDDDDDDDDDD
@42T
GGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATC
+
@<<DDADDDH?FHIEHHIGEAH>GHGFIIIGDHBGB>DDFHIBFEGCHGH@HIGHHII)==CEEAB;?AACCC?AB?=CC@@B<?CCC>CCCCCCCBBCCC
@42U
AGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACT
+
17+7?A7AC@BCAC=@=3?ABCB7+7A<A+2:=1?:?<4==A>BABBBB<..55A=>>=BB?>A?AAA@@@@@@@@>>>=>????=;9;=====<=<<9;9
@42V
GTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAAC
+
@@@=DDDDHADDHIIIII@FIIIGIIHGDHBFHIEBHIIIIIGIIIGGIIEGHIIIIIIIIGHHHEFHFFFFFFCBECCCCCCCC:@CCCDCDACCCCC
@42W
ATTTATAAGTCCAGAGATGAAGCAAACAACAGTGGAGTCATAAATGAAAGCTTTGAAGGTGAAGATGGCGATGTGATTTGTTTGAATTCAGATGACATTAT
+
@@@A?BDDHHHDHGIGIGFBEEHE@AFAFGDF?CEFEFGGHIIGGAFHGFDGHGHDEGGGHCHFHIEIIIG<E???CBDDEECCCCCD@CAAC@C>@CCCD
@42X
GTTTCGCCGGCAGTCTCGATGATAGTATTTCTGCTGCAAGTACTTCTGATGTTCAAGATCGCCTGTCAGCTCTTGAGTCACGAGTTCAGCAACAAGA
+
@@@FFF<DHFFHGIJFIIGHIGIJJGHIJIJIJFGIJJJJCDGGIGIJJJJGIIJJJJJIIHGHFFEFFFEEEEECDCCCCBBDBBDEDDDDDDDDD
@42Y
GCTTACAAATTTGACTTCCACGGCATTGCCCAGGCTCTGCAGCCACATCCGACCGAGTCGTCCATGTACAAGTACCCTTCTGACATCTCCTACATGCCTTC
+
@@@DDDDDHDDFFIIBEEHGIA:@CGIGHIEG@;@;BDEGG?9?FD?@FHBHGHB<9(7=,;55@>-;>;:C>:CCCCCCACD:AAA>ACCCCCCCCCCCC
@42Z
CCTGGCTCACTAACTAACGTGAAAGCCTTACAGAAATCTCCAGGACCTCAGCGAGAAAGGAAGTCATCTTCATCCTCAGAAGACAGGAATCGAATGAAAAC
+
=;=1?=+<<22??CAB9@;A+7?=2<=CA>>A*@AB4*110?*0?;A;***/:AA/ABB26=2AAB?=>?>?9?>)6;35363;>;;:=:?:9>?>??==8
@430
GCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACA
+
?;:DDDD3CFDHDEHGHEGIIF@HGIGGICHGBFGDHHGHHIGEGB@;@CGEIDA=EEEEEE;;6>;A5>A;AC3>B>A>::@C>3@>>?ABBBB05?A4
@431
GAAACATTTGAAATGGGAGAGGTTGTTGAAAAGGATACAACAGAACTCGTGGAAAAACTTGCGGTAACCAAGCGAGAGAAATTAGAGCTGGCACAGAGACT
+
83-((2.=))9).::68)<35(>(6@<83=@?99;)1<::><(<.:1=(0.'76:369;3.)-':'5=3.==<(3;;5;<<((,(,++82(((+(++((3:
@432
CACATACCAACGGCGAGGATCACTTCAGCTCTGGCAGTTTTTGGTAGCTCTTCTGGATGACCCTTCAAATTCTCATTTTATTGCCTGGACTGGTCGAGGC
+
@@@DDDBDBAFFAFHBGHBEFDHIIIGEABBBDGG=@=CCFHGIDCEFEEHFCDEFCDCCECECCCCCCCCCD>DDEDA@AA5>ACCBA<CBBCA<BBB>
@433
TGGAATGTAAACTGATTGAGCCTGAAGAGGTGGCCCGACGTTGGGGCATTCAGAAAAACAGGCCAGCTATGAACTATGATAAACTTAGCCGTTCACTCCGC
+
CCCFFFBDHHGHHJIJIJJJJGJJJIJEHIFGIIJJBGGHBGGIJIJJJJIJJHHHHHFFFFDDDDDDDDDDEDDDDCDDEDCDDCDCDDDBBDDDDDDDB
@434
GGGCCCTCCGTTATTACTATGATAAAAACATTATGACCAAAGTGCACGGCAAAAGATATGCTTACAAATTTGACTTCCACGGCATTGCCCAGGCTCTGC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHJJJJJJJJJJJJJJJJJJJJHHHHHHFFFFFFFEEEEDDDDDDDDDDDDDDDDDDD
@435
ATGATCCGCCGCCTCTCCCCGGCTGAGAGAGCTCAGGGACCCAGGCCGCACCAGGAGAACAACCACCAGGAGTCCTACCCTCTGTCAGTGTCTCCCATGG
+
@<@DDDD;DH:CFFDB??F@F?@F@GH???7BB=FHGFEHIIIF;CBE>A@8@B@B?9?@C?@B?<<8<?(233>::@<8>?9:A>@AC:(4::CC<><A
@436
CTGCTACCCCCCCTGCCTCATTACCTGGCTCACTAACTAACGTGAAAGCCTTACAGAAATCTCCAGGACCTCAGCGAGAAAGGAAGTCATCTTCATCCTC
+
C@CFFF4AFHHHHIJJJJJGJJJJJIJIIJIIIGIJJJJJJJHGGIJHGHJHHHEEFFFFFFFEEDEDDDCDDDCDBDBDDDDDDDCDEECDDEEADDCD
@437
TGCCCCCCAGGCATACAGCCAGCCGGTCCAGGGGGATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTC
+
8=7A;DDDADDD3<CEDDC):8C8008?DB/3?6/;85(=A>;A@(;66(6--;5>>>>A?<?(5>(5,4::44>+4+8<>>?>>??>:<>34:>A4>>9>
@438
AGGACCTAAAGGTGTATATCAAATCAGCAAACAAATCAAAGCTCATGATGGCAGTGTGTTCACACTTTGTCAGATGAGAAATGGGATGTTATTAACTGG
+
@@CDFFFFHHHHHHHGIIHJJIIJJJJIJJJJIJIJIIJJJJIJJJJIIIJJJJBFFCFHIIEGIJJIGHHGIFGIHEHFHGFFFDDCCEDEDEEDDDC
@439
AATTGGATCTGGATCATTTGGAACAGTCTACAAGGGAAAGTGGCATGGTGATGTGGCAGTGAAAATGTTGAATGTGACAGCACCTACACCTCAGCAGTTAC
+
C@CDFFFDHHHHH@GHIGJJIE@DGHHIJIJJGHIJJGIICGGGEIGIHGBDHBFHCHIFHGIGIGHHEGGAGEAA;;AE;;BEFE@@ACCDACCCD:@(5
@43A
GGACCATGTGATGCACCTGCTCCAGAATGCTGACCCGCTGAAGGTGTACCCGCCACTGAAGGGGAGCTTCCCGGAGAACCTGAGACACCTTAAGAACACC
+
C@@DDDFFHGHGHIGIJJIJIJJIJGGHIIJIJJJJ)1?DHIJFDFBFIHIIIIEGHIGIHHGFBACECDDDDBDDBDDDDDDD@CDDDCDDDDDDDCCD
@43B
AATACAACCTCCCACACCGACCAATCCTCACGATTGAGTGTCAAAGAAGACCCTTCTTATGACTCAGTCAGAAGAGGAGCTTGGGGCAATAACATGAATTC
+
CCCFFFFFFHHHHIIJGIJHJJJJJIJJIJJJIJFIGGHGDHGGCHIJIJIJJJJIHHHHHHFFFFFFEEEEEEDDBBBDDDCDDDDDDDDDDDDDDDDEC
@43C
ATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJIJJJJJJJJJJJJIJJJJJJJJHHHHHFFFFFFEEEEEDDDDDDDDDDDDDDDDDDDDDDDEDDDDDDDDDD
@43D
CGGGAAGGACCCACATACCAACGGCGAGGATCACTTCAGCTCTGGCAGTTTTTGGTAGCTCTTCTGGATGACCCTTCAAATTCTCATTTTATTGCCTGGAC
+
@@@?DD?DAHFDFIIIIIIIIEB@GGHHIEFHIGAH3=@ED@=AAHCD7;BEFDD;@>@5>>CCCACA@ACCDDC?AA@A:>@:CADC>CDCACACA@A?B
@43E
CTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGAC
+
<@@FFFFFFFHGFBHGIHIJJGEGGHEHJJJIIJH2BDCGFB8B<=CADGG@FEGIEGAAE3=A?@DBBB?;ACCC>B0<ABBA<BBCD@>>CACCCDC
@43F
CCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATT
+
CCCFFFFFHHHHHJJIJJBHIJJJJJJIIIJJJJJJJJDHIJJJIIHIGIJJJJJJJJJJIIJJJGIJJHGHHHFFFFFDEEEEEDDCDDDDDDDDDDDDD
@43G
AGGACTTTCGCTATCGATCTCCTCATTCAGGTGATGTGCTCTATGAACTCCTTCAGCATATTCTGAAGCAGAGGAAACCTCGGATTCTTTTTTCACCATTC
+
?@@D7?DDAFAFFF9FHECHECHGGIIA9CECCFAGFGBGHI@HGCHIIEHIG>AHCGHGHI<FDEEC;CDCEHEE??BDEEC<BBACDCCCBCC@@>@@@
@43H
AAAACAGAGAAGCTGCTCGAGAGTGTCGCAGAAAGAAGAAAGAATATGTGAAATGCCTGGAAAACCGAGTTGCAGTCCTGGAAAATCAAAATAAAACTCT
+
CCCFFFFFHHGHHIJIJIIHHDGCEFFEHIGGGIIHIIHGGGGIJIJGGEGGEGHGIIIGGGEFCED9>=AECCCCCCCCDDCDDDCACDDCCDDCAC>A
@43I
GTGCAAACAGAAAACCAAGTCATACCAGTGCTGTCTCAATTGCAGGAAAAGAAACTCTTTCATCTGCTGCTAAAAGGGGTACAGAAAAAAAGAAAGAAAA
+
@?@DDF?DHB??>GHGGABH@BFGI@GGC?949:C><GGGHGGGC@GIIIIIIC>GGHGFGBC@FGGGIGGGHIHE1?>9BCCCCEC?BB@=5??@CBCC
@43J
AGACAAGAAGGAAAAGAAAAAAGAAAAGCACAAAAGGAAAGAGGAAGTGGAAGAGAATAAAAAAAGCAAAGCCAAGGAACCTCCTCCTAAAAAGACGA
+
7+=A<A7A;ACC+<??CCBB>AAAAA>:AB>ABB<78AA7>BBBBBB.==BBABBBBAA>;A>@;';5=?9(55=:((328892(3838;=8:39805
@43K
TCACGAGTTCAGCAACAAGAAGATGAAATCACTGTGCTAAAGGCGGCTTTGGCTGATGTTTTGAGGCGTCTTGCAATCTCTGAAGATCATGTGGCCTCAGT
+
@CCFFFFFHHHHHGIJJJJJJGIJIJIIJJIIIFIGGIHIJGGIIIDGIGGGECHHGFDECFCACE@B@BDDDDDDCCDDEDDDCDDDDCDCCDDDDDDDA
@43L
CAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATG
+
@@@FFFFFHHHGHJIGIIGEIIHIGGIBGGIJJJJJFDFHDGB@FDHGGCHIGGHII8@CHHJ>GGG>CECED?BBBDDDDDDDDDDBBDB<<@CCCCECD
@43M
GCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCT
+
?@@:A:?ADFH>CBEEHHHIGHGHHIIGHEEEEHIBHGFGHIAGHGFFGDCDBEHIIAAA;FGDED@ECCA7BDC>>?BCAA;>::>ACACCCC>@C???C
@43N
AGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGAC
+
<?=BDDDDHHBHAHGGGGIIGEAEHGEGED3C@>GG>FHIEEHCGEGD@BFA=CDHGIIIG?EGHIGGHEEFFFFFFCEECC@ACDCCCAC@@9@A??B<>
@43O
AGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACT
+
@CCFFDFFGGHHDIHIJJJJJJJJJGHJIJJJJJJJ:00?DFHIJIIIIIIIJJIJGIJIJIJHHHEHHFFFFDEEDEDDDDCDDDDDDDBDDDDDDDD
@43P
ATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGG
+
:>7A<2<A+?+<2A<+?177C7<27+1?AB=;:?;7?4?<7098=A97*/8)<B=1.(..===.=A;>)...7>>7=@@@;;=5(,,,5=9(,,,,(++(8
@43Q
CAGGAATCGAATGAAAACACTTGGTAGACGGGACTCGAGTGATGATTGGGAGATTCCTGATGGGCAGATTACAGTGGGACAAAGAATTGGATCTGGATCAT
+
@?;DADDD8<AF>EGHIIGFIG@A9<+<CFBB0??F?FG?DH@FG?F@D2CFFG@@FCGI@GGFHHB1?DB@CC;>3(=?@B=>:9AA:@C:@CACCC<BC
@43R
CCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCT
+
CCCFFFFFHHHHGIJJJJJJJJJIJIIJGHIIJJJJCGHGIIJIJJJIIIIHIJJJJGIJIJJJIIGHFHHGFFFFFDEEDEDDDCDDCBBDDBBBDDDD
@43S
CAAGAAATAAAAAACATGAAATTAGAGCTGACTAATTCTAAGCAAAAAGAAAGACAGTCTTCTGAAGAAATAAAACAGTTAATGGGGACAGTCGAAGAACT
+
@CCFFFFFBHHHHJJIJJJJIIJJHIIHIJJJJIGIIJIJJJIJIJJJIJJJIJJJIEHJJJJJJJGIHHFHHHFFFFDFEEEEDEBDDDDDDDDDDDDDD
@43T
CGGGAAGGACCCACATACCAACGGCGAGGATCACTTCAGCTCTGGCAGTTTTTGGTAGCTCTTCTGGATGACCCTTCAAATTCTCATTTTATTGCCTGGAC
+
CCCFFFFFHHHHGJIJJIJJJJJIIJJJJIGIIJJJJJJJIIJHHHHFDFFFFDDDDDDDCCDDDDDDDDCDDDDDDDDDDDDDDEEEEEEDDDDDDDD?B
@43U
TTTAAACTGATTGAGCCTGAAGAGGTGGCCCGACGTTGGGGCATTCAGAAAAACAGGCCAGCTATGAACTATGATAAACTTAGCCGTTCACTCCGCTATT
+
?;?DDDDDHDFH?EHGIGHGC9ABC9FEGHAF??FDFHIII<;CHG@@GADEEHCHEEE?BCCCCAACCCCCCC@CCCCCCCCCC<5<C9>@ACBBBBBC
@43V
CAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATG
+
@@@:DDBFGHGGHIIIHIEHEHIAHHIB?GHIIIEFHIB9GEDGGHGHIEBDGHA)...==@ECE@DEEH26=CCBBCBCACCC>CCB@CBCA@CCCCDCC
@43W
CATGAAGAGCAAGCCCCCTCCCACGTATGAGTCGGAGGAAGAGGACAAGTGCAAGCCTATGTCCTATGAGGAGAAGCGGCAGCTCAGCTTGGACATCAAC
+
C@CFFFFFHHGHGIIJJJJJJJJIJEIIHGG?DFHHIJGGHIGEGGGIIEGGEFEHFFFFFCDEECEDEDCC?AAC>@D>B>BDDDDDDDDDCDCCCDDD
@43X
TGACACCTGTGTTGTCCCAGAAAAATTCGATGGAGACATCAAACAAGAGCCAGGAATGTATCGGGAAGGACCCACATACCAACGGCGAGGATCACTTCAGC
+
CCCFFFFFHHHHGIIJJJJJJJJJJJJJJJJJJJJJDIJJJJJJJJJJJJJJIJJJJJHHHGJJHDHFFFFDDDDDDDDDDDDDDDDDDDDCDDDDDDDDD
@43Y
CAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCAACAAGAACGCAGGATGGAAACAAGCCCACTGAGACTTGTCAACCTCAATCTAC
+
;;38>????:>?4>@)63)@>)).6:597:(((.;?1(<?1)))0.<(966=)<)<''39':).(998==7;5;7(;(3(5<5;(:,(5(6665::;/6/+
@43Z
GGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTAC
+
CCCFFDDFHHHHHIGGIIJIGIJJJIJIJJIJJJJJJIJIJJJIJJJJJJJIIJIHHHHHFFFFDD>BDDCDDDCDD@CCDDDDCDEEDDDDDDBDDDDDD
@440
CGAAGAACTTCAGAAGAGAAATCATAAAGACAGCCAGTTCGAAACTGATATAGTACAACGAATGGAACAAGAAACACAAAGAAAGTTAGAACAACTCCGGG
+
?@@7;A>:ADFHDFGIIGEHGFFHIIIIGAEFHIGGGGHIDIICHBFIEIIII8DFEFGGCF<@AHHGHHCEEEEEDECCCC@CC;-;;AC:AC?>CC?9>
@441
CACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACC
+
CCCFFFFFHHHHHJJJJJJJJJJJJIJJJJJJJJJJJIJJJJJJJJIJJJJJJJJJJJJJJIJJJJHHHHHFFFDDDDDBDDDDCDDEEFEEDDDDDDDDD
@442
GGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCC
+
@CCFDFFFHHHHHJJJJJJJJJJJJIJJJJJJJJIJGHIJJJJJIJJJJJJJJJJJJ@GIJIJJJGFHHHFFFFDDEEDDDDDDCDDDDDDDDDDDDDDDD
@443
ACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGT
+
@?BFFFFFHHHHHIIJIIIJJJJJJJJJIJJJJJJJ3BFGHFIJJJJJIJJJJIJIIJJIJJEIHFHFFDDDDDDDCDDEEFEFDDDDDDDDDDDDDDDDC
@444
AACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCT
+
(;5=(<:=@?:<16):7==8<?><)=66;).:<9>7);>39:;>??<;7>:=>97;;;8816)8>?;9;>>)86)9==???<>;070;08;0;<<;8:96:
@445
GCATGAGATTGAAGAGCTAAACAGAGAGCTGGAAGAAATGAGGGTTACCTATGGGACTGAAGGACTGCAGCAGTTACAAGAATTTGAAGCTGCCATTAAAC
+
=;;A<A8A+?+<C7C7;=A+?3A7?+227<:@371?7?=:7=?509)0*9AA*9;7.=(.8>BA9)(7).)==77;>@;>5>@6>33;>=;;355(:=9>?
@446
CTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJIJJJJFJJJJJJJJJJJAGIIJIIHHHH?DFFFFFEDEEEEEDDDDDDDDDDDDFDCDDDDDDDDDDDDDDDDD
@447
CTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATCCAGCCAGCTTGTCCAGGGGTATGGCACTGGGGCTTATGATACCACCACTGCTACAGTCACC
+
@C@FDEDFFHDFFIEHFHIHIJJJJJCHIDHG:6D;8)***/*8-.8C))..7@7=@>=4,);((((6>?(''395:5(((55(:0(2(((+4::@(4:A:
@448
GCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATAC
+
;??DFFDFBFBFFHHGHGHIHCHIIIGGECEHGDFHIIIIIIGGBHIEHIIGHFEGEDHHHCEBFFFCEDCCCC@CBD?BCCCDCDDC?><CCDDCCACCD
@449
TGATGACATCTCCTGTGACTCTCACCTCTCAGACAACTAAGACAGATGACCCCCAATTGAAAAGAGAAATAAGGTTAATGAAAAACAGAGAAGCTGCTCG
+
@@?DDF;BFDDDBHGGHIHIIIIIIIIIIIIIAGCHFEGGGGHIGIGIGIIIIIIIGGHGGIIDGHIIHEHHHFDDCDFFFDCDEDBCCDDDCACCAAC?
@44A
TTTGTGGATGGCACCAGAAGTCATCAGAATGCAAGATAAAAATCCATACAGCTTTCAGTCAGATGTATATGCATTTGGAATTGTTCTGTATGAATTGATG
+
@@@FDFFDDFFDHIHDGIHHCEHGFHHEEHHGIGGFHIJIIIGJIHIGGBGFHIJIIAFGHGFGE@FE;FHGCHIIJGEEFBAEECBE;;;@@DAACCAC
@44B
GAAATCATAAAGACAGCCAGTTCGAAACTGATATAGTACAACGAATGGAACAAGAAACACAAAGAAAGTTAGAACAACTCCGGGCAGAGCTGGATGAGATG
+
CCCFFFFFHHHHHJJJIJJJHHHIIIJAHHIIJJJJHHIIJDIGIJJJJJIJJIIJJEHIJJJIIJFHHHFGGFFFFFEEEDDDDDDDDCCDDBDDDCCCD
@44C
TCACAACCTCTCCAAATACACAGACAAACTCCAGAAAGCAAGAATGCTACTCCCACCAAAAGCATAAAACGACCATCACCAGCTGAAAAGTCACATAATTC
+
CCCFFFDDHHHHHJJIJJJJJIJIJJJJJJGGHIJIIJJJJIIJJGGIJJJJJJGIJJJJJGGIGIIHHHGFFDDDD@CCCADDDDDDDD>ADDDDDDDED
@44D
CTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTAC
+
@;=DD;D?C:DFH@:AACGIBCCECHIIGEGB@F@DEHEHCGGBGHIGCHIIDHEHB?BB>@BBACC>CACDCCCCECACACCBCBB>CA>C:882<>8CC
@44E
GCTCTCCGACAGCGCCAACGCCAGCTGTATCACCTGGGAGGGGACCAACGGGGAGTTCAAAATGACGGACCCCGATGAGGTGGCCAGGCGCTGGGGCGAGC
+
@@@FFFFFGHHHGIIIJGIJIJJJJJJIJJJIIJJIJJIIIJHFFFFDDDDDD@BBDADECCDDCCDDDDDDDDDDDCDDABD@BDDDDDDBDDDDDDBDB
@44F
GTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTAC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJGIJJJJJJJGHHHHHHFDFFEEEEEEDDDDDDDDDDCDDDDDDDDDEED
@44G
CGTGAATATGGCATTCTCTCAGTCCAACCCTCCTTCGGAGTTGCACAAGGTCCACGGATCCAGAAACAAGCCCACCAGCTTGTGGAACCCAACGTACGGCT
+
@@@D?DDDFFDFFGHEGBEGGFBEFHHGEHIGGGIIEHD@BGGDGDHIGGHEIIIIIIEGHEHHFCDCDEECCCBBB?BCCCACBAACBBBB?BBBB@@@B
@44H
CAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCC
+
@?@DDA?DHDD:<EFCDBC<CEHAB+CBEEHF?A=@FH<DFBB9B;??<?BF?CCGIHEECA7@CDAGHA=AHE@BBC;;A;6=@@CCA;A@>@@@C((59
@44I
CAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCT
+
@@<DDD>D?DFDFGEHIJJGIEEGIIIIC>GCHJJJIJJIIEEDGHGI@@FHIJIIIIIHHHFEFCEFECEC?CACBACC@@DDDDCDD@CCBA>CCDDD
@44J
GTTGTGACTATGACAAGCAGGGGTGCTGAAGGATCAGTTTCTAAAGTAAATAAAAGTTTTGGTGAAGAATCAAAAATAATGGTGGAAGATAAAGTTTCTTT
+
?@@DFD?>BAFDFIIIIGIIGIA??BGGGIEIGEIIHFGEGD?G?B9BFHIEBDEHIGIA>E@EEGAACE;=;CBD?CEE@A.;5;>>BCCCCCBCDACCC
@44K
GTCGCTGGAGCGGGCGGAGCTGTGCGAGCGCCTCCTCACTAGGATCCATACATTTAATGTGGATCCACCTTGCCAGAACGTGGCAGCTTTAACGGAAGGGG
+
;-(-3-(-(.)8(3(0-<';3).))'-'','33'((,,77((,(5(3((++(+3(82(+:((+3(((58(((+8+8:((5+((&(((+8:<</6&+()208
@44L
CGAGGAGGGAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCA
+
=<8ADDDD)<<?FBBBGF@9CF9?GG>DGDF@@@BAFEC@FDDFFECDFEFF=EE>?@;79;@38<92;?9?BA@@@A@B:AAA?><BBB?@@?@B8<?
@44M
AAAGGAATTATGCAAAAGGTGGCTGGAGAGAGATATGTCTACAAGTTTGTGTGTGATCCAGAAGCCCTTTTCTCCATGGCCTTTCCAGATAATCAGCGTCC
+
@@@DDD8D<CFHBHIIIGIHIICHHI@HGGGH@GEGHIIAGHIIIG9?B@FFGCHGGIIIGIEHEGBDHHEHEHFEEDEECCCCCCECCCCFCCCC@B5?@
@44N
TGGGAACATAAAAAGTATACCTGCCAAATCAGCTGATCTTGACCTCATTAGCTAGTCCCATAGTCAAATGTTGAGTTTAACTGGTTTAGACTTTTTTTTCT
+
?;@DDADDBH84C<E<CEFHICCEECDHCHB99CB3:C?<4D9:B<BFF<?FGHDB?F>FHC>88=8@FAGG4:CDEE=;?A?>);@B;C;;C@CC?BBCC
@44O
ACTTGATTAGAGACCAAGGATTTCGTGGTGATGGAGGATCAACCACAGGTTTGTCTGCTACCCCCCCTGCCTCATTACCTGGCTCACTAACTAACGTGAA
+
@@CFFFFFGHHHHJJJJJJIJJJJJHHJFGFHIJJJIIJJJJJJJJJJJEHIIHIIJJIJJIIJHFDDDDDDDCDEEDDDDDDCDDDDDDDDDDDDCDDD
@44P
GCAGTGTGTTCACACTTTGTCAGATGAGAAATGGGATGTTATTAACTGGAGGAGGGAAAGACAGAAAAATAATTCTGTGGGATCATGATCTGAATCCTGA
+
@@@DBDDDFFFFFIBFEG4CIHA?FHHEFIEHIIIFEIFFDEGFIIIEIBFEIFEFFDFFIFIEEIIFFFFFFEDDD?BBCCCBBABBBBEBBBBBBBBB
@44Q
CCAGGACCTCAGCGAGAAAGGAAGTCATCTTCATCCTCAGAAGACAGGAATCGAATGAAAACACTTGGTAGACGGGACTCGAGTGATGATTGGGAGATTCC
+
?@?DDDDDHFHHHGGIJIGHGGGGFGIGIIIGIGIGGHIIIJJGHJJIJIIIGIIJJJIJJIIJHGHGEHDCFFDCCBACDBD:?CEDDFEDDDDDBCDDE
@44R
CCCCGAGCAGCGGCCCCTCCGGTCCCCCCTGGACAACATGATCCGCCGCCTCTCCCCGGCTGAGAGAGCTCAGGGACCCAGGCCGCACCAGGAGAACAACC
+
@@@DDFDFFDD<FGIIIFHIGH@@DFH@AGCE@AHEBFFFFDCED;??BB:<9?CCBBB557?AC@B?ACCC?38?B@BDA@BBB359<?B<A@8AC9C?@
@44S
CTTACTATGAAAACCATGGATACCAACCGGAAAACCCCTATCCCGCACAGCCCACTGTGGTCCCCACTGTCTACGAGGAGCATCCGGCTCAGTACTACCCG
+
???D7ABB<CDC:E;A3+A3C4<<+<<@):?:D)?6?@)?*9?DC0@@D;=(-=16;..;6;;;??8=5>A35:<;:6&2214:35;;??3>:>>>AA98.
@44T
GGGCAGATTACAGTGGGACAAAGAATTGGATCTGGATCATTTGGAACAGTCTACAAGGGAAAGTGGCATGGTGATGTGGCAGTGAAAATGTTGAATGTGAC
+
CCCFFFFFHHHGGHIJJJJIJJJIIIJJJEHGIIJIJGJJGIIGIJJJJIIJJJJJJGIIJJC@FIGJIHH?CEHF;@CBEC>AEDDDCACDACDDCCCAC
@44U
GGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGA
+
@?@=BDDDBFHHBEG@EDCE>FDEE@EF@H;;GH<FGGGGB8D<BDHGGGH;BFHCH@H@:@GHH2@=DHEEH@@EEF>@>C35(;>(=C;BB95?CC@C
@44V
CTACTCTTCATGGGCTATTCCACAAAGCCACAACTGGCTATTGTTACCCAGTGGTGTGAGGGCTCCAGCTTGTATCACCATCTCCATATCATTGAGACCA
+
@C@FFFADHFFHHJJIIJIJIIIGIJHIJJIJJJIJJJGIJIJGIJJJJJJGHIFGBHGEGEGHIIGHGGHHFDDCCCEEEEAEECDDDCDEDCCCDCDD
@44W
CGACGTTGGGGCATTCAGAAAAACAGGCCAGCTATGAACTATGATAAACTTAGCCGTTCACTCCGCTATTACTATGAGAAAGGAATTATGCAAAAGGTGGC
+
@BBDDFFFGADFHGIJIJIIIIIIIJFIG@DCCAH@FGIIGHIIHGGGGIHGIFCHGGGHGHHFGDFDACCCCDDCCCDDDCBBDDCCACDEDCCCD@@B?
@44X
GGCATGGAATTTAAACTGATTGAGCCTGAAGAGGTGGCCCGACGTTGGGGCATTCAGAAAAACAGGCCAGCTATGAACTATGATAAACTTAGCCGTTCACT
+
?7@BD>8;DDBHFIBEHG<EH@?AC>FFFGHIEI?EFCCCFEDGBEHIIIIAEEHEFACE>BACCC<=?@BCCCCC@ACCCCAACCCCCCCC>C@@BC?CC
@44Y
CTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTTATGGGC
+
CCCFFFFFHHGHHJJJJJGIJJJJJJIJJJJIJJJIJJJJJJJIJIIJJIIIIJIJJIJJJJHGHHHFDDDCDDDDDDDDDCDDDDEDDD9>9BDDDDDDB
@44Z
GCCACAAACTGTGGTGATGACATCTCCTGTGACTCTCACCTCTCAGACAACTAAGACAGATGACCCCCAATTGAAAAGAGAAATAAGGTTAATGAGAAAC
+
CCCFFFFFHHGBHHCFHJJIJGHIEIIIJHHGIJJIIIJJIJGICGGIJIJJJIIGIJIGCHEIJIJGGHEGHHFFFFBCCCEDDDDD;ACDDDDDDDDD
@450
CGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTT
+
@@@;DDDDFFFFFIIIIFIEGIFI@GFIICIFIIIIIIIIIEIIIEIIIIIIIIIIIIIFFFFBDDBDCCCCCBBBBBBBBBBB@35AABBABBBB>?ABB
@451
GGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGC
+
=++=4ADADD4<CEEE@EDCAF?@ECDEB<)@??<D;BD199D??CB<BCDCC>3@@845?9;>@@((;5;A<(:;5(>559((832<;8+2<>>>>AA<1
@452
AAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTAC
+
@@@FFFFFHHHHHIEIIIJGIHIIJJJJJJHIIJJIIIJIIIJJI@FHIJJGIEFHHFFFFDEEEDDDDDDDDCCDDD@CDDEDCCDDDDEDDDDDDDCDD
@453
CTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJHJJJJJJJJIIJJJJJJHIIJJJJJJJJJHHHFFFFEEDDEDDDDCEEDDDDDDDDDDDDDDDCDDDD
@454
CTCACCTCTCAGACAACTAAGACAGATGACCCCCAATTGAAAAGAGAAATAAGGTTAATGAAAAACAGAGAAGCTGCTCGAGAGTGTCGCAGAAAGAAGA
+
@@@FFDEFDFHHGIIAFHHIIIEGE@HHCHAG@:GFGIGEDFGFDBFGFEFGGGBFHHIIIIEGHIIGEAEFFCBDB>CB;'59(,5>?<??<CCC>AC>
@455
GGCAGAGGAAAGCAAAAGGAGCAGAAATAAAGACAACAAATGAAGTTGTTTTGGCTGTGGAGTTTCACCCAACAGATGCAAATACCATAATTACATGCGGT
+
@@@FFFFDHHHFFGIJJGIIEIJJJJJIJJJEGIGIEIJJGJIJJHHIGGIJIJJGJCFIHICHHHHHGHEFFDDCEEEDDCCDDDDCDDDEEDDDCDDDB
@456
CTCAGTCGGATGGGCAGAGTCCTTCCAAGAAGCAGAAAAAAAAGAGAAAAACGTCAAGCAGTAAACATGATGTGTCAGCACACCATGATTTGAATATTGAT
+
CCCFFFFFHHHHHJJJJJJGIJJJJJJJJJJJJJJJJJJJJJJIJJJHHHHFFFDDDEDDDDDDDDDDDDDD@CDDDDDDDDDDDDDDDEEDEDDEEEEDE
@457
CAAATTCTCATTTTATTGCCTGGACTGGTCGAGGCATGGAATTTAAACTGATTGAGCCTGAAGAGGTGGCCCGACGTTGGGGCATTCAGAAAAACAGGCC
+
@@@D?DDDHADDHIGIFEIIGCHBDEGECHGGGHFFGGHIFIJIJGBHIGHBFIIIIIIJGJCCDE?CHEFDC:8;?B@BDD@9CACDACCDDDDDDDB?
@458
TGGATCATTTGGAACAGTCTACAAGGGAAAGTGGCATGGTGATGTGGCAGTGAAAATGTTGAATGTGACAGCACCTACACCTCAGCAGTTACAAGCCTTC
+
CCCFFFFFHHHHGJIGIHIJIJJJJIIGGJJFHIIJJJJBFFHG?DHHHID@BGIIGIGHDCEIG@@EGGGA@GHHHEEDFFFEEEEECCDDDDCBDDDC
@459
CCTCAGTCCTCACCATGCCTCAGGAGGTCAGGGCAGCCAGAGAGCATCCCACCTGCTCCCTGCTGGAGCAAAAGGCCCCAGCAAACTTCCATATCCTGTTG
+
?@?DDADB?FFBDEGHG;AI>G@G<C?2:?E?8?DD=FHGGEGHGIGGHHHIACHC>==EAHD7=7;BEBE;>@?B=?@?@B?CA@@A@CCD@4(4:(:@A
@45A
ATGGCAGTGTGTTCACACTTTGTCAGATGAGAAATGGGATGTTATTAAATGGAGGAGGGAAAGACAGAAAAATAATTCTGTGGGATCATGATCTGAATCCT
+
8?@AD3+2A,2<CBFF<CFF9FA:,3CHH+<+*?<@<C?9):?:BFE4*0B?B@B6?FA/=.@3)=7AAEE26?B:?).6@AC@;3;=>>@@BDBBB:>(5
@45B
GGAAGGACCCACATACCAACGGCGAGGATCACTTCAGCTCTGGCAGTTTTTGGTAGCTCTTCTGGATGACCCTTCAAATTCTCATTTTAT
+
CCCFFFFFHHGFHHIJJJGGGIJIGIIIHIIJIGGIIIIGEHIBEHAEHHFFDDEEE>CDDDDDDCDDDDC<<CCCDCDDCDDDEEEEEC
@45C
CAGCAACACGTTTGAAATGAATGGCAAAGCTCTCCTGCTGCTGACCAAAGAGGACTTTCGCTATCGATCTCCTCATTCAGGTGATGTGCTCTATGAACTCC
+
@@CF?DDDFFDFFEHHIICFGIEGIEHHIIIGGIIGBGHCEHIEHIIIIGHCG;FHHIHEHIIIGHFGFFFFFCEEEECCC;>3;A>;@@:ACCDCDCCCC
@45D
GTATGCTTGCCTTCTCAAAGTAAAAGATGATTTAGAAGACAGTAAAAATAAACAGGAATTAGAGTATAAAAGTAAACTTAAAGCACTTAATGAAGAGCTTC
+
CCCFFFFFHHHHHJJJJJJJHHIJJJJJJJJJJJJJJIIJJJIIJJJJJJJJJJJJJIJJJJJJGHIIJJJJCGIJIIIIHHHGHGFFFFFFEEDEDEDDD
@45E
TGAGAGACCACTCTTTCCCCAAATTCTCGCCTCTATTGAGCTGCTGGCCCGCTCATTGCCAAAAATTCACCGCAGTGCATCAGAACCCTCCTTGAATCGGG
+
?=;BDBA?FFHDHGIIHBEAFE@DFEH@GGGIAF>FFGGIIGH3<FF=FHHGAAHIG;CEHACD=?B@C>C?@8>?>ACCACCCCCABB?BCCCAC>ABBB
@45F
TACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCT
+
CCCFFFFFHHHHHJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJAGIIIJHHHHHDFFFFEEEEEEEDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDC
@45G
CCAGGCAGTTTTATGATGACACCTGTGTTGTCCCAGAAAAATTCGATGGAGACATCAAACAAGAGCCAGGAATGTATCGGGAAGGACCCACATACCAACGG
+
CC@FFFFFHGHHHJJJJIIJIJJJFIGHIJJJJIJIJJJJJEIJIJJJIGIIIIJJJGGGJJGJIJJJIGFEEDEFDEFDDD@DDDDDD@BDDDDDDDDBB
@45H
CTCCATATCATTGAGACCAACTTTGAGATGATCAAACTTATAGATATTGCACGACAGACTGCACAGGGCATGGATTACTTACACGCCAAGTCAATCATCC
+
;599=<).@4@<>@?>?;<@(9<>>>:<@8?81.)6=>>?=83)03>893:)=(0<77797>9;))6(-9>77)39=;6;99=(3;<<<55;===5;(3:
@45I
CCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCAT
+
CCCFFFADHHGFHFHIIGDHGIIIIJEHIIGIFHIGGIIGGIIEHJIEIIIJGEHIJGGGIIJIB<B>BDA@CEEEEEDDDDDDBBDBBBBDDDD>CCCDD
@45J
CCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGGTAAGGCCAT
+
@@@FFDDDHHHFHGHIJEHGHJJFHEHIJIJJJJIJFIIHBGCFDFHIGIIJJIIJJIIHCGHIIIIIIHFFFF?DECEEECDDDCCDDDDD:ACCCDDDD
@45K
GAAAAGTTCTGTCTTTGATGAAGACAAAACTTTTGTAGCAGAAACATTGGAAATGGGTGAGGTTGTTGAAAAGGATACAACAGAACTCATGGAAAAACTTG
+
@@@F?DBDFHDFFIJJIGIIGIJJJJIJGIEHGIIHGGDGGHJJJEGHIIGIDDGDG@?CFEBFHGHHJJJJFHDHHHFFDF@CECCCDDDDCDDDD:@AA
@45L
CTTTAAAGCAAGAGAAAGAACAAGTTTCATTGAGATGTAGAGAGCTAGAAATCATTATTAACCACAACAGGGCAGAAAATGTACAGTCATGTGATACTCA
+
@CCFFFFFGHHHFGIJGIJJJJJJIIJJJJJIIJIIGFHIJIIIJJIIIJJIJEGIJJJJJJJJJJJGGGJIIFFHFFFFFFDDEEDCCEDDDEEEDDDD
@45M
CTCAAAACTAACTCAAAAAGCCGGAATCCTAGTCAAGGTGGCCAAAAGAGCAGAAGGAACGGGCGCAAGATCACATTAACATCCAAGCAGCCTTATTACA
+
0((2=@)(2))2))).9;(((.(((1(:)).8<)37))))(7(<>)(.9)7).)8>:().''5''''3,8((,5(((+((8(43((5+(+(2(2((+(++
@45N
GAGAAAAGGATGAGACAATGAGAGAATTTTTAGAGTTGACAGAACAGAGTCAAAAATTACAGATTCAATTTCAGCAATTACAGGCTAGTGAAACTCTG
+
@@@DDBDDBHHFHEH9E9AFHC@FAGHDGHGDHHI?DGHIEHIGCACBGHBG<FGGGGIFGE>AC=FHIBHGIGIFHHBEACEEECCC3>@CCCC>:;
@45O
CCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTAT
+
CCCFFFFFHHHHHJJIJJJJJJJIJJJJJJJJJJGIJJJGIJJJJJJJJJJHHHFFFFFEEEEEDDDEDDDDDDDDDDDDDDDDDDEDDDDDDDDDDDDDD
@45P
AGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACC
+
<;?DADDDFD<?0@<<CCCDCD>GE<D@DA<FD*?DHDF@F@@DHCFGH8866A/5?>;BC66;ACCCCCC;BBBB@@8<?B8<CCA>@:>44::4:3><<
@45Q
CTCAGCCCCAGCAGAACAAACCAAAGAAAAAGGAGAAAGACAAGAAGGAAAAGAAAAAAGAAAAGCACAAAAGGAAAGAGGAAGTGGAAGAGAATAAAAA
+
CCCFFFFFHHHHHJJJJIJJJJJJIJIJJJJJIIIHJJJIJJJJJJJJJJJJJJIJJJHFFFEEEEEDDDDDDDDDDDCDDDDD@CDDDDDDDDDDDDDD
@45R
GGAATGTATCGGGAAGGACCCACATACCGACGGCGAGGATCACTTCAGCTCTGACAGTTTTTGGTAGCTCTTCTGGATGACCCTTCAAATTCTCATTTTAT
+
CCCFFFDFFHFFHJJJJJJJJJJJJJJJJIJIJIJEHFFEEEEEDDDDDDDDDDDDDDDDDDDDACDDDCDDCDCDCDDDCCDDDDDDDDDDEDEEEEEDD
@45S
GCCAAGGCAATCTCCTTATCATGGGGACTGAGGATGCCTCCTCCTTGCCTGAAGCCAGTCAAGAGGCAGGGAGCAGAGGCAATTCCTTTTCTCCTCTGTTG
+
???BDD?=?FBCFFG@FAAA@>E<3BFFAA<:83*?DB?B;)9?@FFF@@BEG@FBB=@=7=DAGDA(5/?=<<2=3???89?CA5>CCA:(4>:<:@>AC
@45T
CTCAAGTAAGCTCTTTATTAGATGGAGTTGTGACTATGACAAGCAGGGGTGCTGAAGGATCAGTTTCTAAAGTAAATAAAAGTTTTGGTGAAGAATCAAA
+
CCCFFFFFHHGHHJJJJIJJJIJIJGJFHIFEHIIJJJI@HIJIGIJJJFHGFIJGJJFIGHIJJJHJHHGHHEHFFFFFFEEEEEED?BCCDDDDDDDD
@45U
CGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCG
+
@@CFFDDDHBHDFFG<EDHIHIJJJJJIJIGEHIIGFHJJEHIJJHHDFFFFEEDEECCCDDDDDDDDDDDDDDDDDDDDDDDDDDDDCDCDDEDDDDDD@
@45V
CAAGTGCAAGCCTATGTCCTATGAGGAGAAGCGGCAGCTCAGCTTGGACATCAACAAGCTCCCCGGCGAGAAGCTGGGCCGCGTGGTGCACATCATCCAGT
+
@@CFBBDD?HFHHIIIFIIIIIIIIIIIIIIIIIIIIIEIIIIFHGIDFFGIIGCCHGGACEFFFCBBBC@BC9:@CBBBBBB<@B28ACCCCCCCCCCCA
@45W
CTCCTCACTTGGATCCAGACATTTAATGTGGATGCACCATGCCAGACCGTGGAAGATTTAACGAATGGGGTTGTGATGGCCCAGGTTCTTCAAAAGAT
+
CCCFFFFFHHHFDGIJHHIJIIJJIJJJFIJJJDHGJGIIIJJIGIDHGFDFGGHEHHIEIIJGIHGHHHBDAC@CA;5?CBDDDCCDCDDECDCCD@
@45X
GAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCC
+
@@@DDDDDDAFFDGFB8AC@D@FGGIG<DBFHDHFEHGGE@ACD@@DGHICEHFE?DF@?BC@>@EC@/28@AB<9B<ACCCBCACDD>ACDDD@BBDDBD
@45Y
AGACAGACAATAGCTGAACAAGAAAGTAAACTTAATGAAGCACATAAGTCCCTTAGTACAGTGGAAGATTTGAAAGCTGAGATTGTTTCTGCATCTGAATC
+
:=:=B:DDBF:DA<2<:??<?ACFGEH9FEHD@C?CBDF<FGFG<?FFFIIE@B?BBBFBB88;===C@==FE@DC;@>=A7A;B?BDDC>@BC>;;A;AB
@45Z
ATAAAGACAGCCAGTTCGAAACTGATATAGTACAACGAATGGAACAAGAAACACAAAGAAAGTTAGAACAACTCCGGGCAGAGCTGGATGAGATGTATGGG
+
@@@DDBDDHFHACF<CFH=GGGEBHGG@FEGH@FHGFIIIIGBD@FFHGHI>FHIED>DGHGIII@EHEHHEEEEDCCB@BBBCC??<@A@C@AC:@ADCB
@460
CTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTC
+
<@@DDDDDHBFFHHEEGIDGIIIEHIDBDCGGHIBEHIGFGGIGII@HHEGGGHEHIG@G@HGGIIHHHEEA>AC25>35>5:>BBC?CB:@CCCECCCCC
@461
GTTTTGGCTGTGGAGTTTCACCCAACAGATGCAAATACCATAATTACATGCGGTAAATCTCATATTTTCTTCTGGACCTGGAGCGGCAATTCACTAACA
+
BB@FFFFFHHHHHIJIIJJJJJJJJGIIGIJJJJJJJJJJJJJJJJIJJJIJJFHIIIIJJJJIIIJJIHHHHGGFFFFFEEEEDDDDDCDDDDDDDDD
@462
CTTCAAATTCTCATTTTATTGCCTGGACTGGTCGAGGCATGGAATTTAAACTGATTGAGCCTGAAGAGGTGGCCCGACGTTGGGGCATTCAGAAAAACAGG
+
@@@?DDBBDFHF?EGHG<EHCDA?FH3AAC@CH@HBGEHIEFFHHHHBDDDGFEEG@;CA>@G=@A:AC)6;@BD98,8;89?B79BCC:AA>:@<?<<9<
@463
CTGAGACTAGTCAACCTCAATCTAGCACAGGGGGATACAACCAGCCCAGCCTAGGGTATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTAC
+
?8+B?=B>D3<AD:A222<F??FF<F<AF;@?)?)00?9D8/((.--=6A57A)7(7777);AD((...;>AAA>;-(;;555=???5(44>:22<002>A
@464
GCACAGACCACCCAGCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGG
+
@@@FFFFFHHHHHIHIIIGGIJIJJIJJJJJJJJHJIJGJJGJJJJJJJJJJJHIJJJJIJHHHHHFHFFFEFFDEEDDDAADCDDDDDDCCDDCDDCCDD
@465
GAACAAACCAAAGAAAAAGGAGAAAGACAAGAAGGAAAAGAAAAAAGAAAAGCACAAAAGGAAAGAGGAAGTGGAAGAGAATAAAAAAAGCAAAGCCAAGG
+
@@<DDDFFDBFBFEHGEGHDHGEAGGEHGGIEHAGHIGIIBGHDHGGIIGGCEGCCHHEF?;BCECEABBB;@C:>C@BDC>CCCCCDD<<CCC?AB?ABB
@466
ATCTGGATCATTTGGAACAGTCTACAAGGGAAAGTGGCATGGTGATGTGGCAGTGAAAATGTTGAATGTGACAGCACCTACACCTCAGCAGTTACAAGCCT
+
@@@BFFBDDHHDHIIIGABHIHFHIGGIIHGAHHGHGGIIGI?FBFHDGHGBF?FCHGIIDG>GGIIGCGGEEC@AEEE@@@@CCEA@>@ACCCACCC9?C
@467
GCCCTTCCGACCAGCAGATGAAGATCATCGAAATCAATTTGGGCAACGAGACCGATCCTCATCAGCTCCCAATGTGCATATAAACACAATAGAACCTGTC
+
@@@DDFDBFHDAFGGGIEEHGGEHIG?FDGGICFHGIGECGIGI<F2ACGBBEEHFAAAEDCD@A>@ACDCDDD>AC@CAADDEDCDDBDDDC@CDDD:>
@468
CGCAACGGCTCAACCACCTTAGTCTACCCCGCCGGTGGGGGGGACCCAATTAAAGACCGAGACCTATTGTGATTTTTCGGTCAACGATCGGGCGAGCGTCG
+
0955(0((8-(.2::3-3(:))28)=)3((-76(''-''-'&)&02288(5(++(((+&)&&&+(+3625((++2::(002&)+(&+(+)5&&)&0-0&(&
@469
CTGGTTTACAGAGAAACCCACCAAAAAGAATAATCCTATAGCAAAGAAGGAGCCACACGACAGGGGTAACCTGGGGCTGGAGGGAAGCTGTACTGTCCCAC
+
@@CFDEFFHHHDHGIIIIBHG@FHIIE>BA<DAFFDB<<:?BGH;DD;F;9=F@E=C;;4==BDF>'9>A5(5?B8/'88(8?5922+(+(+4(++>@3:<
@46A
CTGGCTCACTAACTAACGTGAAAGCCTTACAGAAATCTCCAGGACCTCAGCGAGAAAGGAAGTCATCTTCATCCTCAGAAGACAGGAATCGAATGAAAAC
+
@CCFFFFFGGHHHJJJJJHIIJJJJIJJJJJJJJJJJJJIGIIIFJIJIJIIGIGIJJJJJJGHHHHHHHFFFFFFEEEECEDDDDDDDCDDDDDDDDDD
@46B
CAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGAC
+
CCCFFFFFHHHHHJJIJJIGIJJIIIJJJJJIJIJJFIIJJFIJGEHIJGGGIIJIJJJJIIIGHHEHGFFFFDCEEEDDCDCDDDDEDDDDBDDDDDDCD
@46C
CAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGG
+
CCCFFFFFHHHHHJJJJIJJJJJJIJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJIIJJJJJJJJJHHHHFFFFEEEEEEDDDDDDDDDDDDDDDDDD
@46D
GGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACAC
+
CCCFFF?DDFHFHJJIIIJIJJJJIJIIFHHHGHIDHGHIIIJJJJJJJJIJJJJIJJIIJJJJJGIEHFFHHFFFFFDDCEDDDDDDDDDDEDDCDDDD
@46E
CTTCATCCTCAGAAGACAGGAATCGAATGAAAACACTTGGTAGACGGGACTCGAGTGATGATTGGGAGATTCCTGATGGGCAGATTACAGTGGGACAA
+
@@@DBD?BDCDHDGBHIIIIHIIGGCCFGIIICGGGFGCDBFHGHIB:?AE=;=A8=@;=D@;@;CE;9;?;?ACCEEEABCBBCCACCC;>C<<<?<
@46F
TGGTTATCGAGGAAAGGACTGTAGAGCTAATGTTTACCTTCTTCCGACCGGGGAAATAGTTTATTTCATTGCATCAGTAGTAGTACTATTTAATTATGAGG
+
@@@DDDFFHHFHGJIJJEDGEHGIIIJFIJJJIIGGIJIJIJJIIJGIIIJJHFFFEEE>BCEDDEEDEEDDCDDDC>CDFFEEDADDEDDDECEEEDDDD
@46G
CCACTGCATCATGCATCTCCAAACTCAACTCATACACCGAAACCTGACCGGGCCTTCCCAGCTCACCTCCCTCCATCGCAGTCCATACCAGATAGCAGCT
+
@@<DDFFDCFHHHIBF@<BHGHGGBGICH>F??GGCHBDGHGDHIII>BAGBEGHHHEE?BD@D:AE>A;===@CCCBB788A@ADCCCCA?CCCCCC<?
@46H
CAAATTCTCGCCTCTATTGAGCTGCTGGCCCGCTCATTGCCAAAAATTCACCGCAGTGCATCAGAACCCTCCTTGAATCGGGCTGGTTTCCAAACAGAGG
+
CCCFFFFFHHHHFHIIJIIIJIJJJJIJJJJIGFHGIIJIIJIJJIJJJJJJGIIGCEHFFFFFFEEDDDBDDDDDDCDDDBDBDD?CDCDEDDDDDDDD
@46I
ATGAACTGAATATAAAATTGCAAGATACTAACTCTCAAAAGGAAAAACTCAAGGAAGAACTAGGACTAATTTTAGAAGAAAAGTGTGCTCTACAGAGAC
+
C@@FFFFFDHHHHJJIJIJJJJJJIJIJJJJJJIIGIJJIJJJJJJJJIJJIIIJIGGEIIJIJJJJJIJJJIIFEFHHHFFF@BDCEEDEEEDDDDDD
@46J
GGCCGAGATGAAGCTCGTTCATCGGGACTTGGCAGCCAGAAACATCCTGGTAGCTGAGGGGCGGAAGATGAAGATTTCGGATTTCGGCTTGTCCCGAGATG
+
@@@FFFFFGHHHHIGIIIIIFI@FHIIIFIEHIIIIIIIIIIGIIIIFHGGGIIGHEHFFFDBD;@@<@ACCDCCDDCDD?BBDCCDBDB9<>CDB5<.8:
@46K
GAAGCCATCCAGCCCCCGGCAGGAGAGCACACGCGTGATCCAGCTGATGCCCAGCCCCATCATGCACCCTCTGATCCTGAACCCCCGGCACTCCGTGGATT
+
?@@DADBDBHFBDGIIIIIIGGIG;BFG@GIIIII@GCEEHHFFDFFFEEECCABBCB?CCCCAACCCBCCCCCDCCCACCCCCCCCBB5@?ACBABB?CC
@46L
CACCCCCTTCCCACCACAAGGCTTTAAGCAGGAGTACCACGACCCAGTGTATGAACACAACACCATGGTTGGCAGTGCGGCCAGCCAAAGCTTTCCCCCTC
+
@@CFFFFFHHHHHGIJJJJIIIIJJJJJJJJJEIBGHIJJJJJJFEE=CDHGJGJIHHHHDFFFDEEEECDDDDDCCC=BDDDBDDDDDCCACCDDDDD@D
@46M
CTTCAAATTCTCATTTTATTGCCTGGACTGGTCGAGGCATGGAATTTAAACTGATTGAGCCTGAAGAGGTGGCCCGACGTTGGGGCATTCAGAAAAACAGG
+
@@@DDD>DDBFFHIIGGGIGHGGGIGGFHIIFEB?CD@FDHE9DDGIIIIGHH<FHIBCHGI9;E3)==7?;@BDCCCBBB99>B>BCCA:@ACCCCBBCB
@46N
AACTGACACTACCACCAGATCACCAACGCCGGCGCCAGAATGGGGCGAACCAAAATGACCGGCGAAGTAGGGGAGCACCTCGCCGGGGCTTTGAAAAAC
+
(-(2-:)96:)<9).(((.);=>@)((((1-7--''''3).:=?5'',,006687((+((&&&&&))(+2280&)&(((+2(08&&556&((+4+(3+0
@46O
AGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGG
+
@@@FFFFFHHHHHIIII>BH:FHGIIBGGIGHHGHIGGGGHGIHGIIGGIIIIGGIIIIIIIIIIHIGHHFD><A@DBDDCCDCDCBDDBCDDCDCADDCD
@46P
GAACTGGCCTGGGCCTGTATACCGGATAGTGACTCAGTGCTTGCAACATAAGCCTGAAGACAGGCCCAACTTTGCCATCATTTTGGAGAGGAGTGAATACT
+
((((-))(.=3@(2.-(<>4..)<3(1<)1.).>????;1>).<>?3(<)<>1.<(<?3)<>?5((--9(;668=1(((:--(-:5;2(82((,8:52(((
@46Q
CTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTC
+
@@@DDDDDD?FFHIEHGCIGGHGGDHCHEHHFEDHIIBDHIIIBCDEDHIIIIIICHCFEHEGGHGGGHF>?E?@DFFF@@@C@EBAB?C@ABCCBCCCDA
@46R
GCCAATTACCATGTTCATTCCTTTCGATGTTGACAACTATGATGACATCAGAACGGAACTGCCTCCTGAGAAGCTCAAACTGGAGTGGGCATATGGTTATC
+
<@@?DDDDF<BDDGB?F<HGHIIDH;BFHGHGCA<<FEG9?CHB:CD<?*3:?DD<;D-8=FCE@=@FEG:DDEEEFF@;BDC3@(6?B<=;@@CC(>A55
@46S
GAAATTGAAATACTCAGACAAGAAGAAAAAGAAAAGGGTACACTTGAACAAGAAGTTCAAGAATTACAACTTAAAACAGAATTGTTAGAAAAACAGATGA
+
CCCFFFFFHHHGHJIIJJJJJIJJIJIJJJJJJJIJJJDGIJJJJIJIIJJIJJJIIGGGIJJJJJJIJIJHHEHHEFFFDDEDEEEDDDDDDDDDDDDD
@46T
ATGAACGATGATAAACTTAGCCGTTCACTCCGCTATTACTATGAGAAAGGAATTATGCAAAAGGTGGCTGGAGAGAGATATGTCTACAAGTTTGTGTGTG
+
1;;9??1>>??<=?=<<>>.@7=-8=9=1:<=2==;???=<8:><1>????;>?==>3=?>?9;8=9?9=?0=)336;;;3=7==?==:(5;==;5,8;7
@46U
CCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGC
+
CCCFFFFFBHHHHJJIJJJJJJIJJJJJJJJJJJJJJJJJJJJIJJIJJJJJIJJIJJJJJJJJJJJJHHHHFFFFDEED@CDDDCDDDDDDDDDDDDD
@46V
AGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCT
+
@@<DDFFFHHHGFIJJIGGCEGIDGHGHHJJJJJJIGJIIEHIIJIDHIJJIGGHIJGHHEDFFDEDECCCCDDDDCC>CCDC?AABDDBDDCDDDACDD
@46W
CCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTAT
+
CCCFFFFFHHGFHIIJIJJJJJJFIIHJJIIJJJGHJJJIIJJJIJJJJJJHGHFFFFFDEDCEDDDEDDCDDDCDDDDDDDDDDCDDDDDDDDDDCCDDD
@46X
GTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACA
+
8=?DD2B;DBD:CCE7EE@D=C<ED>EED;C?*11?DDA?9B**8B*)?DD<B=CCC>C4@D;@C57.7=)(;AD7;;>=>;;>?;959>>5>AAA>AA
@46Y
TCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAA
+
;8;18@9@((89/->(8@@9?<)..@@>9>96.>393?36????<?93:>;;=?891.;-.65=?'=3608=>:;733;2557=5(,;=6:6:<:2:(2
@46Z
GCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGC
+
CCCFFFFFHHGHHJJJJJIJJIJJJJJJJGHIJJJJJJJIJIIIJIGJIJJIHIJIIJJJEGGIIEHHHGHFFFFFFEEEDDDDDDDDDDBDDDDDDDD
@470
CAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGC
+
CCCFFFFFHHGHHJJJJJJGIJJJJJJJJIJIIIJIJJJJJJJIJJJJJ@EGIJJJJJJJJIIJJGIIHHHGHFFFFFEEEEDCDDDDDDDDDDDDDBDDD
@471
AGAACTCAGCGACACTACCTGGGCCATACAGACTGTGTGAAATGCCTTGCTATACATCCTGACAAAATTAGGATTGCAACTGGACAGATAGCTGGCGTGG
+
C@CFFFFFHFHHHIJJJJJHIGIHJIIJI>GDHJIGIIJJJGFFGIIIEBHGGFHEHGJJGJGGEHHHHEDEEFFFEEEDDCDC?CBCCCCCCDD@B@@D
@472
GCCCTCAATTCGACTGCCCCGGGCACTCCCTGTGGAGGCCTTGAGGGTCCTGCACCTCCATTTGTGACAGCATCTAATGTGAAGGCCATTCTGCCCTCTA
+
<;??:B;2AF?C<CB@>?ADFEEIFFI;DCF?G<DF=A=;BF@=..;-76@A>AC=B;?)6>;;6;35>;?BBBBB:@@DE@>:((58?ABDDBB?>@?B
@473
GTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGAT
+
?@@ADDDDHFD;:A<<E<:CCAG@@<CE8CGHEH>C@D@?G9D??9?FD@G=GHI9@@=FC;@D3?ACE??>BE:>>@@C;>>CC?@@=;8?B?444@>>>
@474
CGGGGAAGGAGGTCCTGTGGCCACTCTATCCAAGCCTTCCCTAGGTGACCGCTCCAAAATTTCCAAGGACGTTTATGAGAACTTCCGTCAGTGGCAGCGTT
+
CCCFFFFFHHGHHIIJIJJJJJIJJJJJJJJJJJJJJJJJJJJJJGGIJIJJJIJHHHHHFFFFFFFDCEDDDDDDDDDCDDDDDDDDDDDCCDDDDDDDD
@475
GTCAAAAATTACAGATTCAATTTCAGCAATTACAGGCTAGTGAAACTCTGAGAAACAGCACTCATAGTAGCACAGCTGCAGACTTACTACAAGCCAAACA
+
CBCFFFFFHHHHHJJJJJJIJJJJJJJJJJJJJJJJJJJIHIIJJIJJJJIJJJJJJHIJJIJJIJHIIIJGIJIJIHHHHHFFFFFFEDEEABDDDDDD
@476
GTGAGGGCTCCAGCTTGTATCACCATCTCCATATCATTGAGACCAAATTTGAGATGATCAAACTTATAGATATTGCACGACAGACTGCACAGGGCATGGAT
+
@@@F?DADFDFA>GIIIIIIIIIGBDGHEGHD?FGGED@>GEHDAED?GHIIH@DFF<BB@CCFHEHEIE@GDHIEH@CDFDDECD>AA5@=?BBBC?ACC
@477
CGATGTCTGTCTCAGCCCAGGAGTTTGGCTGAGCAGTGAGATGGATGCTGTAGGCTTGGAGCTGCCTGTACAAATAGAGGAGGTCATAGAGAGCTTCCA
+
CCCFFFFFHHHHHJJJJJJJJJJHHIIJJJIJJIJJGIGIHIIJJJIJJJIJIJJJJJJHIJIIJIJIFHGHHHFFFEFFBDD=CDCDC@CCBDDDACC
@478
AACTAAGACAGATGACCCCCAATTGAAAAGAGAAATAAGGTTAATGAAAAACAGAGAAGCTGCTCGAGAATGTCGCAGAAAGAAGAAAGAATATGTGAAAT
+
CCCFFFFFHHHGHIJJJJJIJJJJJHJIIGHJGGGIIJJJDGHGIJJJJJJJJJJIJJJIJIIDHIHHHFFFFFDDDDDDDDDDDDDDDDDDDEE@DCDDC
@479
CGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTAT
+
CCCFFFFFHHHHHJJJGHJJIJJIJIHIJJJJJJJJJJJJIJJJJJJIIJIJJJJADFFFFFDDBBDDDDDDDDDDDDDCDDDDDDDDCCDDEDDD@4@CC
@47A
AGATGATGGAAAGTGAGTTGGCTGGGAAGCAGCATGAGATTGAAGAGCTAAACAGAGAGCTGGAAGAAATGAGGGTTACCTATGGGACTGAAGGACTGC
+
CCCFFFFFHHHGHEGHGIIIIJJJJJJIIIJJIJIIGIIGJIJJIIIJJJJJJJJFIJEHIIJIJIIIJGGFHHFDEFEEEEEECDDDDDDDDDDDDDD
@47B
GAAGATAACTGTGTCCAGAGGACCCCCAGGCCATCCGTGGATAATGTGCACCATAACCCTCCCACCATTGAACTGTTGCACCGCTCCAGGTCACCTATCAC
+
@@@DDDDEFHDFFIIIGGIGGHGGHGIJEGIIGJGHIGHIEEGIFB?=FGIJGEEDGHI@CHE?EBEED@AA@CECEDDCCA6=8?@D>C@@::4>ACC@>
@47C
TTCTGAAGAAATAAAACAGTTAATGGGGACAGTCGAAGAACTTCAGAAGAGAAATCATAAAGACAGCCAGTTCGAAACTGATATAGTACAACGAATGGAAC
+
CC@FFDEFFHGFHJIJIIJHJIGGGIGID@GHFGIJJGGHIGGGEGGIIJJIIGG<FHHHIJIIGGIJEE>AHEFFEC>CE;@CDCDDCCCDDDBDDDCD>
@47D
ACTATTCAGAGACCTTCTCCCTTTATTCCAGCTGTCTAACTGACAAGACCTTTCTCTCTTTCTTTCTGCCTCATGCTCTCTCCAACAGGCTTGCAGCCAAT
+
CCCFFFFFHHHHHJJJJJJIJJJFIIJJJJJJJJIJGIIJJJIJJJIJJIJJJJJJJJJJJJJJJGJIJJIJIJIJGIGHHHHHHFFFFDEEDDDDDDDCD
@47E
CCAGAGATTTTGCATATGACTCAGAAGTGCCTAGCTGCCACTCCATTTATATGAGGCAAGAAGGCTTCCTGGCTCATCCCAGCAGAACAGAAGGCTGTATG
+
@@CFFDDDDFFHHIGIJJIJJGIGHGI<A<FHHIIGIGGIJIJJGGGGIIHJJGGIIGHCDFGHIIIIGGIJJJHGGHHHFDFFEDEEEDDDDDCDDADDD
@47F
TCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACC
+
@CCFFFFFHHHHGJJIIIIJIJJJJCHHJJIJI*BGIHIIJJIJJGJDHIJJJJJJGIJJJJHHEHFEFFFFEDEEEDDBBDDDDDDDDDDDCDEDDDDDD
@47G
AAGAAAGACAGTCTTCTGAAGAAATAAAACAGTTAATGGGGACAGTCGAAGAACTTCAGAAGAGAAATCATAAAGACAGCCAGTTCGAAACTGATATAGT
+
@CCFFFFFHHHHHJJJJJIJJJJJJJJJJJJJIIJJJIJJJIJJJJJJJJIJJJJIHIJIJJJJJJJJJHHHHHHFFFFFDDEEDDDDDDDDDDDDEEDE
@47H
CTCAAAGCCGTGCACGAGCAGCTTGCAGCCCTCTCTCAGCCCCAGCAGAACAAACCAAAGAAAAAGGAGAAAGACAAGAAGGAAAAGAAAAAAGAAAAGC
+
@@@FFDDFFFHHFIIGHHGIGIIJJJJJIDGIJIIJJGGIJJIJJJJJJJIJJIHHEEFDDEFEECDDDBDCDC<CDBDDDB?CACCDDDDDD@BDCDC?
@47I
GCTGAATCACAAGAAGCTGAATTAGAGAGGCTGAGAACACAGCTTCTATTTAGTCACGAAGAAGAGCTTTCCAAACTGAAGGAAGATTTAGAAATTGAAC
+
CCCFFFFFHHHHHJJJIJJJIJJJJJJJJJJJJIIJJIJJJJJIJJJJIJJJJIJJIIIJJIJJJJJHHHHHHFFFFFFEEEEEDBDDDDDDDDDDDDDD
@47J
AACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGG
+
@?@D??DA:ADHDGH@FGEAEHEGIFGAHIIIIIDG@F*BD@FFGHG>FHGIIGGG@DGG;?EECE>>BECACBCCBB=A?AA;;>ACCCBBBBBBB?::9
@47K
GACCACTTTGGCAGATGAAGCTCAGTCTCTGAAAGATGAGATCGACGTGCTGAGACATTCTTCTGATAAAGTATCTAAACTAGAAGGTCAAGTAGAATCTT
+
@;1?D=DDAABCDD;E4<E@?<<A9<9?<<A*:CF**1:**1:0?@F67B;F4BF;CC4./7.7@CC@EAA.73=);?37;B@>666(;5(--->;;>>@;
@47L
GAAATTTAAACCACAGCAGCTGACTGCAGTTCAGAGGTAAATGGTTGCAGTTTTGTGATGAGAACAGGAAAGACTACAAATTTATTAAGGGAAGAAGAATT
+
++1?<+?,<A<>;A;37A;++3++2++<A:=<7?B=?B>?**0**08>AB*=<?=/.))9))>AB33.(.=().)=A@>>>??(6((.63;;;;5,,,5:;
@47M
CTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGC
+
@@@DDAD:AC?FFIB4E9AEEGEDFBGCGFBF<@FGBG=FFBGDFEFIIFEEFE@EADC;CEEIEEECA3?@;?@@;@>AD<A>;?==?2>ABB9999:>
@47N
ATTTAGTCACGAAGAAGAGCTTTCCAAACTGAAGGAAGATTTAGAAATTGAACATCGAATAAATATTGAAAAACTTAAAGATAATTTAGGCATTCACTAT
+
@CCFFFDEFDHHHGGGIJGJGGIJJJJIGAHIGIJJJJIJJJJJJJJJJGIIGGIJIIGIIJIEHIJGHJJJGHHHFFFFDDEEADED@EDDDDDDDDDD
@47O
CCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGCCAACCCAGCAGCTGTGGACAGAAGAGTAGCTTTGGTCAACAAAGCAGCTATGG
+
(0-:50<1:>1=)))29).))).)))):))<.)6=.;987;=<<168()9<==3=>?>:6:).3<>?0=));7=8;?3=(66=,(:<3;35((8;;;527;
@47P
GGACAGCAGATACTTGTGCCCAGCAATCAGGTGGTCGTACAAACTGCATCAGGAGATATGCAAACATATCAGATCCGAACTACACCTTCAGCTACTTCTCT
+
7<@BDBDFHFDCFGGIFFGHGBBEHIICHGB1CEFHGDHGHGIGBHDEBBF<@FG@GEGCCC>DG@=AAHHHFDB@B?BCBC@@CA?C?CACCC@CCACCC
@47Q
GGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTC
+
@@@DFFFEFFFHHJGEIGGIIJGJJIJJIIIIGIGIJGJIGFHGGIIIIJGIJGIGHGHIIIIGIEHJAEHDFDDDDDEEEDDEDEDCDDDDCDDDDDDD
@47R
AGGAAAAGAAAAAAGAAAAGCACAAAAGGAAAGAGGAAGTGGAAGAGAATAAAAAAAGCAAAGCCAAGGAACCTCCTCCTAAAAAGACGAAGAAAAATAAT
+
1??;DB??:;AC:8EC<EF@?GICF@CF7)???DDB)9800/?98(.BFDFCCA@AD9.6>A>>?;;(59>?55<9??9@AABA:@B9<358-3<<<?BBD
@47S
GCCGAGGGTATGGGCAGCACAAAGGCCATGAGACAGGGCAAGTCCGGACATGGTCAGGGGCCGAGAAAAGGGCCAGGGCGCCTGGAGCAGAGAGGAAGAGG
+
0-(22(-8-2))2.(<;??@)(()):(030)0>9:76(0<=;/);(-'53.3)).)67=<''3,7,89(3(6(((++&()&8:3(8(+(2((++(+((+89
@47T
ACTCAACTCATACACCGAAACCTGACCGGGCCTTCCCAGCTCACCTCCCTCCATCGCAGTCCATACCAGATAGCAGCTACCCCATGGACCACAGATTTCGC
+
CCCFFFFFDHHHHJJJJJJJJJIJJJJJIJJJJJJJJJIJGIIJJFIJJIHHHHHDFFDBEEDEDDDDDDDDDDDDDDDDDDDBCDDCDDDDDDDDDDDCD
@47U
GTGATGTGCTCTATGAACTCCTTCAGCATATTCTGAAGCAGAGGAAACCTCGGATTCTTTTTTCACCATTCTTCCACCCTGGAAACTCTATACACACAC
+
@@@DDDFFGFHGHJGIGIIJIJFGIGIEH@HIIDAIHIIJGGHGGEBHECHIIGIIIIIJGGIIIIHJFHHEFEEEFFFCEDAEDCCCDDACCEDDBDB
@47V
ATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGC
+
=?<B?=DDFBFFFD3A3<@AHIF@BEGGEIFEFFF;D;?GGFGFFE@FFF:FFICFFEBECDA>C7?>=@?BC;;A;;3;3>ADB(>A3>A@BBBBBBBB?
@47W
CTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGC
+
@?@FDFFFHHBFFIGEAGEEHGHIIIIGGHGH@GGHIIIIIECHIGGEDCFHIGGIGI@GA@EGEHCEHFC>?CFCCEECDEDCABDB2<CCCDDDA>>A
@47X
TTCCATATCCTGTTGCCAAGTCTGGGAAGCGAGCTCTAGCTGGAGGTCCAGCCCCTACTGAAAAGACACCCCACTCAGGAGCTCAACTTGGGGTCCCCAGG
+
@@@DDBD>FHHF?CFGIH<EHHICDF@FH;FCAGDFEH?BFEGDDC7FGHBEGGIGHGCEAECA>C<BDECA(3;AACCA<?9A>:9CCCC@BBBB<ACB?
@47Y
CCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCG
+
@?@DDFDBHHB=FHBCFGGHIHHHIGGG@1?GHIIIICHGIDHCGGIHGIIIIDI>FHICHAFGHAAHGHFBDBBEA@7ABDBDCDDC3>CCCACCA<CCB
@47Z
CAACATTTCCCTGGGTCCTGGAGAAACCCTAGTACCTGGGGATACGGAGAGCAGTGTGATTCCCTGTGGAGGCACAGTTGCGGCAGCTGCCCTAGAAA
+
CCCFFFDDHFHGFIJF>GHGIJHIIICHIIIGFEIGHIGGHDHHIHGGIEHGHHFC=DDEHGIHGH>EFEFEB;@CDDDDDBD<?<?CC9ABD??:>C
@480
CCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTGAGTTGCTAAGAGAGAAAACCAAATAAGA
+
CCCFFFFFHFFHHIGEGIGHIEIIIGGGIGIHIIGE@>FDCHHIGIDFHHHHGHIIAEGHIIIBEEBBD?7@CCCEEDDECCCA?@BCDD=?BBDDDDAC
@481
AGATTTTGCATATGACTCAGAAGTGCCTAGCTGCCACTCCATTTATATGAGGCAAGAAGGCTTCCTGGCTCATCCCAGCAGAACAGAAGGCTGTATGTTTG
+
@@@DDDFDBFHHHIJIIJJDIEICFHHGHDHIIJIIGIJIGFIIIIJIGIJGIIIHGGBEGGIJEGICCIGADDGH>CHDFFFFCECEEDDCBAACCDEE<
@482
CTCCATCCCCTGCACTTCCCTTTCTCCCACCAACTTCTGACCCACCAGACCACCCACCCAGGGAGCCACCTCCACAGCCCATCATGCCTTCAGTATTCTCT
+
CCCFFFFFHHHHGJJJJJJJJJJGJJJJJJJJJJJJJJJJJJJJJJJHIIJIJJJJJIJJHHHFFFDEEEBDDDDDDDDDDDDDDDDDDDDDDCCDEEDDC
@483
CTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGC
+
CCCFFFFFHHHGHJIIIJJJJJJJJIJJJJJJIJJJJJJJJJJJJIJJJJJJJJJGHJJJJJJIGHFHHFFFFFFDEEECEEDDDDDDBDDDDDDDDDDD
@484
GGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTAC
+
@<@DDDFFHGHHGIIGHIIIIIIIIIGGIDFGAFBHGIHEEHIHIDDHHIIGIIIIIIIIDFHAEEFFFEECEECEECDDCD@@DDDBDDDDDCCDCCC
@485
CCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTAT
+
CCCFFFFFHHGBFIJIJIJIGJJJIJJJJJJJJJJIJJJIJJJJHIIJJIIHHHFFFFFEEEDEDDDEDDDDDDDDDDDDDDDDDDDDDDDDBDDDDDDDD
@486
CGCCATGGCTTTGAACTCAGGGTCACCACCAGCTATTGGACCTTACTATGAAAACCATGGATACCAACCGGAAAACCCCTATCCCGCACAGCCCACTGTGG
+
CCCFFFFFHHHGHBGHIJJJIJFHHJJIJJJJJJJJJJJJJJIJJJJJJJJJJJJIJJJJGIIIJJJJJHFFDDEEDDDDDDDDDDBDDDDBBDBDBDDDD
@487
CCTGGAAAATCAAAATAAAACTCTAATAGAAGAGTTAAAAACTTTGAAGGATCTTTATTCCAATAAAAGTGTTTGATTCCTAAGAAAGAAAATATTTTTGT
+
C@@DDFFFHDHHHJIJJJJJGGIIJIJIIIJIHIIGIJJGEGIJJIGGHIHGIGHIJJIIIGIJIJJGG7@@CHGGJJJGGHFEFFFFDDDCCCEEDEDD;
@488
CGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTT
+
@CCFFFFFGHHHHJJJJJJJJGIJIIJJJJJIJJJJGHIIJJIJJIJJJHIIJJJJJJJHHHHFFFFFEDDEEDDCBDDDDDDDD=BCDCBDDDDD@CDDD
@489
GGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCCATTCCTCTACAC
+
8:;DD??:CA?:ABG?CCEFHHHGGHEGGGGE?9E8:):BDDCG?GF8D8DEBCH.==CFIIIII;CGE:CAEE>B@7=ACCC=;;?(5@CCC@CCCCCC
@48A
CAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCAC
+
BCCDDFFFHHHHHGIJJJJJJJJJJJJIJJJIJIIJIIJIJJIJIJIGIJJJFIIIJIIEGHGFHGHH?BCFFFDDCECDDDDDDDBBCD?BBABDDDDC?
@48B
AAGAAGCTGAATTAGAGAGGCTGAGAACACAGCTTCTATTTAGTCACGAAGAAGAGCTTTCCAAACTGAAGGAAGATTTAGAAATTGAACATCGAATAAAT
+
@@@FDDFFFABHDHGGGG;@FCFHIIC>AEGCGGGHGIIJEGHDHIIGEDGGH<GGHHIG@GHIIHGEEEEFA@DEFFEEC@CEECCDDDDACBCDCDDDE
@48C
ATGCACAGGAGGAGAAGCAGGAGCTGTCGGGAAGATCAGAAGCCAGTCATGGATGACCAGCGCGACCTTATCTCCAACAATGAGCAACTGCCCATGCTGGG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJIJJIJJJJJJJJJJJIJJJJJIJJJIJHHHFFDDDDDDDDDDDDDDDDDDDCDDDDDCDDDDDDDDDDDD
@48D
AGAGAAGTGCATGGTGGGCAGGAGCAAGCCCTAAATAGCCCCAGAGGGATGCACAGGGAGGGGAACACTCTGCCATCCCCCAGCAGCTGGGACCTGCAGCC
+
=?@?DD?=AD>FHB2C=GGEA@CFHH@H@DH>D)B?F<FC3?F@FDF>87;FE@CEEE1'9A3/;;A<::::5:>C??ABB<?B?8?>:C@B?@CCBCCC@
@48E
AAAATACATACTCCTGTTAGCCAAGAAGAAAGATTGATTTTCTTAGACTCCATTAAGTCCAAATCCAAAGACTCTGTGTGGGAAAAAGAAATAGAAATACT
+
CCCFFFDFHHGHHIJJJIJGIIIJJJJIIIIJEHIJFIICCDHBCEGGHIJEGGFGHHG@GIGIGIJJIEE>DEGGE=DEHDFCFF>>CCC@CCCCCCCAC
@48F
GTTTACAGAATGAAATGAGTCAAAAGATAGAAACCATGCAGTTTGAAAAGGACAATTTGATAACTAAGCAGAATCAATTAATTTTGGAAATTTCAAAGCT
+
@@CFFFFFHFHHHIIIIIIDHHHBEFGHGFHGGHIIIIIGIFHIIGIIIIIEIGGHHIICEGFCAHFHIIIIIIIHFHHHEHHFFFEDEEEEE;CDDC?A
@48G
GTGAATATCCTACTCTTCATGGGCTATTCCACAAAGCCACAACTGGCTATTGTTACCCAGTGGTGTGAGGGCTCCAGCTTGTATCACCATCTCCATATCAT
+
@B@FFFFFHHHHHJJJJJJJJJIJJJJJJJJJJJJHJJJJJJJIIJIIJJJJJIJJJJJIGHIFHHGIJJJHHGFFFFFFC@CEDEDDCDDDDCDDDDDDE
@48H
GAATCATCACTTAGAGCAACTCAACCAAGTGAAAATGATAAACTTCAGAAAGAACTCAATGTACTTAAATCAGAACAGGACTTGATTAGAGACCAAGGATT
+
@@CFFDFFHHGHGFIGIGIJIJJJHGJIJFHHJJJJIJEIIJGIIJIIJIIGIJIIIGIHGFHHIJJJJJJJJJIIJJGHGGFFFFFFDEEEECDDDDDDD
@48I
CTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJIJJIJJJIJJJJJHGHHHFEFFFFEEEEEEDDDDDDDDDDDDDBDDDDDDDDDD
@48J
TGGCTTACATGAACCACATCATGGTCTCTGTCTCCCCGCCTGAAGAGCACGCCATGCCCATTGGGAGAATAGCAGACTGTAGACTGCTTTGGGATTACGTC
+
@@@DBFFFHHHHHJIJJIJJJIIJGIJIIIIIJIIIIJJJJJJIGGIJJGGJJJJJJJJJHHGGHFDFEEEEEEDDDDD>DDDDDDDDDDDDDDDDDCDDD
@48K
GGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTAC
+
811++A+ACCD;;:CF@:<F:EF>FHH<2:E?F3CCG=GEEE1888==@8FEECAE)==C;;>B@C3355(;5595?5<>>A@A>ADD>:@A?B@BB@@@>
@48L
TGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTGAGTTGCTAAGAGAGAAAACCAAATAAGAATGAATGT
+
??7;D?A??<DF?FF?D@@AECC><CEFBCB@GIFFFDF)*0BF>>FBADBDFEE';'5@(.?)7A?@?>:3;>>>AA;???@3(,9<:535>5(44>@>+
@48M
TGAAGGATCAGTTTCTAAAGTAAATAAAAGTTTTGGTGAAGAATCAAAAATAATGGTGGAAGATAAAGTTTCTTTTGAAAATATGACTGTTGGAGGAGAA
+
==7+?;AA8>A2@C@B>>,?,3,,<=AACB?A@BAA???BB?7*?*?BBBBABABA*9ABBB28>4ABABB7>AAA7(A>A)7?;;);>6>>@@>(;;2,
@48N
TGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCC
+
@@@DFFDDHFFHDDEEHIGHBHIHIJFGIHCGGCCEHICHDBGBFGFGHFGGEGDG=FGEGGGE@=CCEH=A7?BBECCEE>>?@BDCABDDD?CBD<@B
@48O
CAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJHIJJJJJJJJJJJJJJJJJJJJIJIJJIIJJJJJHHHHFFFFFFEEEEDDDDDDDDDDDDDDDCCDDCEDDD
@48P
ATTTATTAGAAGCTTATCCATCCCTATTACTTTTTTAAATGGCATTAGTTCTGTGTGCTATTGGTGTTTATTTGCATCCACCTGTCCAGTTGCTCTGCTGT
+
CCCFFFFFHGHHHJJJJJJJIIHIIJJJJGJJJJJJIJJJJJIIIJIIIJIIIGHGGHGGIJGG8@GHIHIJICIHHGHHHFFFDEEEEEEDDCCCCDAC@
@48Q
TGAAAATCAAGAAAGAACCCCACAGTCCATGTTCAGAAATCAGCTCTGCCTGCAGTCAAGAACAGCCCTTTAAATTCAGCTATGGAGAAAAGTGCCTGTAC
+
CC@FFFFFHHHHHJJJIJJJJJIIJIJJIJJIJJJJJJJJJJJJJJJJJIJJIJJIIIIJJJGJIJJJIHHHHHFFFFFEFEEEEEEDDDDDCCDDDDDDC
@48R
CGGGCCTTCCCAGCTCACCTCCCTCCATCGCAGTCCATACCAGATAGCAGCTACCCCATGGACCACAGATTTCGCCGCCAGCTTTCTGAACCCTGTAACTC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJHIJJJJJJJJIJJJJIJJGIJJJJJJJJHHHHFFFFFEEECDDDDDDDDDDDDDDEDDDDDDDDEDED
@48S
AGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGAC
+
@C@FFFFFHHGFHIGIJIJJJICHHIIJJIEHIJJJJJJJEHGIJIEHGBDGGIICGIBGEHIFAHIJHHHHFFDFFEDDCDDDDDECDDDCCCDDA9?BB
@48T
AAAATAGGTGATTTTGGTCTAGCTACAGTGAAATCTCGATGGAGTGGGTCCCATCAGTTTGAACAGTTGTCTGGATCCATTTTGTGGATGGCACCAGAAGT
+
@CCFFFFFDFHHBHJIJJJJJJJJJJJJJJJJJIJJIIJJJJIJFGIJJJJIJJJIIIHJJJJIIJIGIHIIIJHHHHGDDDEF?CDACCBCDC@BBDDDC
@48U
AAGTCATACCAGTGCTGTCTCAATTGCAGGAAAAGAAACTCTTTCATCTGCTGCTAAAAGTGGTACAGAAAAAAAGAAAGAAAAACCACAAGGACAGAG
+
CCCFDFFFHGHHFHHJJIIIIJJGIFIGIIIJJIJDIJIIJJIIIFEIIJIJJJJIIIHGDFHBGGHIGGGIIHFFFEEEDEDDB;?BBDBBDDBCBCD
@48V
CCCAGCCCCATCATGCACCCTCTGATCCTGAACCCCCGGCACTCCGTGGATTTCAAACAGTCCAGGCTCTCCGAGGACGGGCTGCATAGGGAAGGGAAGCC
+
CCCFFFFFHGHHHJIJJJIJIJJJGIJJJJJGIJJJJIJJIIGIJJAGE?EHHFFEFFFEEEEEECDBDCDDDDDBDDDDDDDDDDDDDDDCDDDDDDBDD
@48W
CTTATTCAAACATCAACAACAGGGACCAGGCGCTTTGTCCTCCATGGGAGAATAATAAATGATGTGGCAAGGGCTTACTCTCCATGAGAGGAATGTGTGAC
+
1=8D1A=DB?DD?:<2<E;AFFA:+221::)1C6?BB9?0B9/009?8BD'.)>78==7)7A))=).(.7,,,,;6@;35(((5>5,,::?(5(4>(:(>(
@48X
CAGGGACCCAGGCCGCACCAGGAGAACAACCACCAGGAGTCCTACCCTCTGTCAGTGTCTCCCATGGAGAATAATCACTGCCCAGCGTCCTCCGAGTCCC
+
1??::DBBFF?DFD?C@??CD?F7:BBE;0?;1?;=CFC78;;@==@7@3?7A7A.7?B@>@A((.>3=?55AB;AB<@@ABB@28<+258@A9&0(3::
@48Y
GGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJIJJIJJJJIJJJJJJJJIJJJJJJIHHHHHHFFFFDEDEDDDDDDDDDDDDDDDDDDDDDDDDDBDDDD
@48Z
GAAAAACTCAAGGAAGAACTAGGACTAATTTTAGAAGAAAAGTGTGCTCTACAGAGACAGCTTGAAGACCTTGTTGAAGAATTGAGCTTTTCAAGGGAAC
+
CCCFFFFFHHHHHJIJIBHGHIJIJJJJGJJJIIIJJIIJJJDGIGGIJGIIJIIIDHIJIJJIJJJIJJJJHFHHHHFFFFFFEEEEEEDDDDDDDDDB
@490
CCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAAC
+
@@@DDDDDDHHDHGFHIJJJJJGHGIJIJJIJJJIIIJIIJJIIJJDHGGGGHHIHIJJJIIIJJHGGEFDFFFEEDEEEEDDDCDDDDCCDDDDDDDDD
@491
AGAGGACAAGTGTAAGCCTATGTCCTATGAGGAGAAGCGGCAGCTCAGCTTGGACATCAACAAGCTCCCCGGGGAGAAGCTGGGCGGCGTGGTGCACATC
+
==1AAA<ACCBB=CB?BC>3473?4,?C4=AABAA=ABA<AAA;><.8.=A=A>)..)7.7A=A=@@);99='8=9;2;(+((+(&)&50;=123((88?
@492
GTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCC
+
BCCFDFFFHFHHHGIEHIGIIIHIIIJJJJGIGIJIJJJJJJJJJJIJHHHHFFHFFFFFFEDDEDDDDDBBDDBDDBBBBDDCDDDCEDDCDDDDD@D
@493
CCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAATGTGACTCTTTCCTCAGGTTCATTCCGACAGGACCACCCCAGT
+
CCCFFFFFFGHDHIIIJIJJIGIHJJJJIGIIFIJIGIGIIIHIGIGGJJJBGGDHEHIJCGHHHGHGFDDFFFECCEEDEEDEC?BBBB?BBBBDBDDDA
@494
GAACCTGTCAACATACTAGATGTTAAAGATGACTGTGGCCTCCAACTAAGGGTCAGCGAGGACACCTGCCCACTGAATGTTCATTCTTATGACCCCCAAGG
+
<;?DDDDDCBFHDEHGGFHEEH@FEHHIGIII>EHHGIGGC@FGEGGDFGBBBF;9BAFHGIGGFEHFBDDEEACCCCC@CDDDEADDCCCCCC<8=BB<<
@495
GCCATGGCGCCTTTGGGGAGGGGTATGAAGGCCAGGTGTCCGGAATGCCCAACGACCCAAGCCCCCTGCAAGTGGCTGTGAAGACGCTGCCTGAAGTGGGC
+
@@<DDDDD<CFF?FG<EGA@F)??@CFCB@DB=F;==@88;;A8:;7?D@BBCB=>B:@?<7?5=@7<??>@4::8<<2+4::3>9@099(+++(4+:(2(
@496
CCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGT
+
CCCFFFFFHHHHHJJHIJJJIIIJJJJJJHJJJIJJJIIIJJJJJJJJJJJJHHHHHHFFFFEFEEEEEDDBDCCDDDDDDBDDDDDDDDDDDDDDDDDDC
@497
GGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGCCAATATAGCCAACAGAGCAGC
+
=?1ABDBBA:AFFEI>E??B;<A:;F2?EDGFGDCBGE?F9FGIEB(?@-B=FCF>@=CEF@E;AEEDBBB(;>;;5(5;?A>5@BBBAB8?<BBBB@?
@498
GGACAATTTGATAACTAAGCAGAATCAATTAATTTTGGAAATTTCAAAGCTAAAAGATTTACAGCAGTCTCTTGTAAATTCAAAGTCAGAAGAAATGACTC
+
CCCFFFFFHHHGHIIJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJIIIJIIJJJJIJIIIIJHHHHHEFFFFFDEEEECEDDD
@499
CCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACAAC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJHHHHFFFFEEEFEEEDDDDEDDDDDDDDDDDDDDDD
@49A
TAAACACAAAAATAATAGAAGAAGAAAAGAAAACTCTTGAGCTAAAGGATAAATTAACAACTGCTGATAAATTACTAGGAGAATTACAAGAACAGATTGTG
+
CCCFFFFFHHHGHJJIIJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJIJJJJJJJJJJJJJGIHHHHHHFFFFFEEEEEEDDDDDDDDDDD
@49B
AAGAAAAACCACAAGGACAGAGAGAAAAAAAAGAGGAATCTCATTCTAATGATCAAAGTCCACAAATTCGAGCATCACCTTCTCCCCAGCCCTCTTCACA
+
;?@DDDDDDHHFF@GHBBHIIIEHHIIGIIIII<FEBFGHEAEHIIDHGGF<??AHEE@BEEECCCCCCBDC:BCCCCCCCC>CCCBCBBBBCBCCCDCC
@49C
TGTAGAGCCCACACCTGGGAAAGGACCTAAAGGTGTATATCAAATCAGCAAACAAATCAAAGCTCATGATGGCAGTGTGTTCACACTTTGTCAGATGAGA
+
1?:BDDADB;+A<<<CGFFFFIIIEEIIEFDF?1:0?:DFE@F<BF@>FEF>D9==8FCCFFF;7..=@C>;AC?;@.7>>.6;;(5>35-5;5::>5:5
@49D
GGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTT
+
CCCFFFFFHHHHHJJJJJJJJJJHIJIJJJJJJJJJJJJJJJJJJJJIIJJJJJJJJIIIJHHHHHHFFFFFDDDDDDDDDDDDDDACDDDDDDD9<0?C
@49E
CACAATACTGGACCTCCCCCACGGGGGGAATCTACCCCAACCCCAACGTCCCCCGCCATCCTAACACCCACGTGCCTTCACACTTAGGCAGCTACTACT
+
C@CFFFFFHHHHHJJJJJJJIIJJJJIDDDDCDDCCDDDDDDDDDBDDDDDDDDBBDDDDDDCDDCCDD?BB?BDDDDDDDDDDDDDCCA@DDCDCDDC
@49F
GCCATACCCCAGCAAAAGCAACCAGGAAGTTCTGGAGTTTGTCACCAGTGGAGGCCGGATGGACCCACCCAAGAACTGCCCTGGGCCTGTATACCGGATA
+
CCCFFFFFHHHGHJJIJJJJJJJJJJJJJIIJJJJGJHIIJIJGGIJJFHJJIGGGIIEEHFFFFDDDDDDDDBDDCDDDDCBBBBDDDCCDEDDDDDDD
@49G
CCAAGGTGAAGAAAAGTCTGAGGGTCCTCTAGGCTCCCAGGAATCTGAATCTTGTGGTCTGAGGAAAGAAGAGAAGGAAC
+
@?@FDD:B?AC>;CCGGH@HCHIAHAC@BEGBDHCFFDDDG?C@FDDGIIFHEH8BF.8BF=FH=D>D)=7=CEDFFDE9
@49H
CCCCCCTCAAAAATAATAGAAGAAGAAAAGAAAACTCTTGAGCTAAAGGATAAATTAACAACTGCTGATAAATTACTAGGAGAATTACAAGAACAGATTGT
+
@;;D?DD<FHHFHFGEHIGFFGC@AGGIIIIEHAHEEHGIEECHIGEHIIIIIGIGGGHGIA@DCEEEAEDBEEEEAACCCAA@CCC@CCCCCCCC?>C@4
@49I
CACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCA
+
@;;BB;AB=ADHFIIBGFC?ED=GDFH;9CF;E;FHEHGGHGBADCAGGICGIGGBGHDGEHCACHE?C;;BACC7?@=?@?9?<@<,5@>AC44:::?>
@49J
CCCAAATGGAGCCTTACAGTTGGCAAGTCCAGGCACAGATGGAGTACAGGGACTTCAGACATTAACCATGACAAATTCAGGCAGTACTCAGCAAGGTACA
+
@@@DDDDDBAFHHGIGGIGFHEGGGGBHEHGHIGIICDHGIJJJDFFHEGGGGGGGIGEHGGIGHIJIGHIHHHHHFFFECCCD>CE@@CCCDDCDCCCD
@49K
CTGTCCAGTTGCAATCCTAATTTTGTCAGGATGGATAGCAAGGCAGTTCACACAGTCTGGATGGCCCAGGTAGTGTCGGTGAGGTCTCTCCTCATAATTA
+
?;?D+ADD:+A:C@EEE>:AF><BA3C4C>AEF7;E*?<D@D>)))09?999?6//9*8)==C>3=2@CC=;7)7.)9',5(.(-((5>3:(9>AAAA>A
@49L
CCAAAGTGCACGGCAAAAGATATGCTTACAAATTTGACTTCCACGGCATTGCCCAGGCTCTGCAGCCACATCCGAC
+
@@@DFFBDFHDDHIGHGBHEFHHJCIIIDGGGHHIIFFHEFDGHBHGGIJC>@FEHIJIAHHFEEFFEDBCC>A=?
@49M
GGGGGGGCTTGCTCTTCATGGGCGCTGGCTCCTTCTTGCTCACATTGCTGTTGCTGCTATTATTTTTCTTCGTCTTTTTAGGAGGAGGTTCCTTGGCTTTG
+
@?@FFDDDDDD?BCCDDDECCDDDDDDDDCDDDDDDDCDDDDD@CDDCDDDDCACDCDADDDEEEEDCDCCBC?ABDDDBDC@CD<?B8<CCCDDDDDDDD
@49N
CCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTTATGGGCAGGAGT
+
CCCFFFFFHHHHFGHIIGIIGJIIGIIIGHIEIIJJJJIGHJIIGIIIJHH@FHGHIJJIHFHFFFFDDDDDBDD@ACCCECDD390?C>CDDDBCBB?@<
@49O
CTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGC
+
@@?D?;=AFBFDFDHD?:FH@DBG@A1:?C???9:?BD??FD9??F*?BFB=;FEC@=@CD;DHC=E?=7;?;?;;;>AC@>@>;@BB9<5(>:<?<CAC
@49P
CGTTCGCAAGTGCAAGCCCCAGATGAATTACGACAAGCTGAGCCGGGCCCTGCGCTATTACTATAACAAGCGCATTCTGTACAAGACCAAGGGGAAACGGT
+
CCCFFFFFHGHHHJJJJJJJJJJJJJIJJJJJIJJJJJJJJIJJJJIIHHHFFDDDDDDEDDEEDDDDDDDDCDDDDEEDEDEDDDDDDDDDDDDDDDDDB
@49Q
TGAAGAACAAGACCACTTATTAGAAGATTATCAGAAAAAGAAAGAAGACTTCACAATGCAAATTAGTTTCTTGCAAGAGAAAATTAAAGTATATGAAATGC
+
@@@BDFBDF>FHGIIHEICHGHI>EEEDH@GFHHIIG;CDHII9FHEIC@@F?FHDGHGGCDGGGHC@=D:CEGGACE@>CDDFFCCCE;@CACCACCDDD
@49R
GCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTC
+
CCCFFFFFHHHHGJJJIIFJJJJJJJJJJIGJJJJJJJJJJJJIJFJJJJJJJIJJJJJIJJIHGHHHFFFFFDDBDDDDDDDCEDDDDDEDDDDDDDBD
@49S
GCACCATGCCAGACCGTGGAAGATTTAACGAATGGGGTTGTGATGGCCCAGGTTCTTCAAAAGATAGATCCTGCATATTTTGATGAAAATTGGCTAAAC
+
???DD>BDAD<<:2C12A@FI;F9B>EE@?;D??DDI866DC8BEEC@@@=C=3).?=?==?;@;7.;6;A>@5=3->A>:35;5,:>:5:5:(++(+(
@49T
AGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCC
+
@@@FFFFFHHHHFIIJIGEIGJGGGIIIIJIJJJJJJIJJJDFGIIJJJGIIIIGJEHGJJGIJIHFHEFFFDDDDBDCD>ACDEEDEDDDDDDDDDDDDD
@49U
TGAGCAACTGCCCATGCTGGGCCGGCGCCCTGGGGCCCCGGAGAGCAAGTGCAGCCGCGGAGCCCTGTACACAGGCTTTTCCATCCTGGTGACTCTGCTCC
+
@BCFFFFFHHHHHJJJJJJIJJJJJJJJJJJJJIJJJHHFFDDDDDDDDCDDDCDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDCDCDD:ACDCDCDDCDD
@49V
CAGGAGCCGGACAAAAGGCCGGTGTTTGCGGACATCAGCAAAGACCTGGAGAAGATGATGGTTAAGAGGAGAGACTACTTGGACCTTGCGGCGTCCACTCC
+
@C@DFFFFHHHFHIJJJIJJJJ@FDGHJJGIJJIJIGHHGHHHGDDEFDEEDEDCDCCDDDDCCDDACDAB?B?CCC9@CCDDDCDDDDDCBDDDDDDDDD
@49W
GGGAAGCCCATCAACCTCTCTCATCGGGAAGACCTGGCTTACATGAACCACATCATGGTCTCTGTCTCCCCGCCTGAAGAGCACGCCATGCCCATTGGG
+
@CCFDFDFHGGFHJJJIJIIIIIJJIJIIGHGIJJIJJIJIJJJIJJIJIGIJIIJJJGHHHGHHHEEFHFFDDDDDDCDDDDDDDDBDDDDDCCDDDD
@49X
TTCAAACATCAACAACAGGGACCAGATAATTTTTATGGTGGGACGAGGATACCTGTCTCCAGATCTCAGTAAGGTACGGAGTAACTGTCCAAAAGCCATG
+
C@@DFFFFHHHHGGJIIGGIGIGHIIGHGGGIGIIJIGGHIJBGGAGHBFHIIIEDHEEEEEEEDBCCDEDCEE@CCDB;;?CCCA>CCDDDDDAADCCC
@49Y
CTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCAC
+
@B@FDFFFHGHHHJGGIJJIIIGBGHHIJJJJJJIIIGGIIIGHHJJEIIIHGIIIIGIGCGIJIGHHHHFFFCDDDDBDCDACCDDDEED@BBDDDDDDD
@49Z
CAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCC
+
CCCFFFFDHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJHHJJJJJJJJJJIJJHHHFFBDFFEEEDDBDDDDDDDDDDCDDDDDDCCDDDDDDDDDDD
@4A0
CTCCTGGAGCTGCTCTCCGTCAGCGCCAACGCCAGCTGTATCACCTGGGAGGGGGCCAACGGGGAGTTTAAAATGACGGACCCCGATGAGGGGGCCAGGCG
+
=?1=AD?D=+++:A2A?E13<C?EF1E:)?BDD:7BB==8/8B4=C7;(.(-5<'',(,,8=;<&58A((+4:(4(489-998<?&)5(4>(5>3.(8<89
@4A1
CCGAAACCTGACCGGGCCTTCCCAGCTCACCTCCCTCCATCGCAGTCCATACCAGATAGCAGCTACCCCATGGACCACAGATTTCGCCGCCAGCTTTCTG
+
CCCFFFFFHHHHGJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJEIJJJHHHHHFFFFFFEEEEEDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDD
@4A2
CCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATG
+
@@@DDFFFHHFHGIEHIGHGHIGGGGGECCHDFGIIGGHHHIIGGIIGHIIJJIIGDEHIIEI<BHBDCB>CCDDEDCC>B8@B@BDDDBDDDDACDCCDD
@4A3
GGCTCATCCCAGCAGAACAGAAGGCTGTATGTTTGAAAAGGGCCCCAGGCAGTTTTATGATGACACCTGTGTTGTCCCAGAAAAATTCGATGGAGACATC
+
:<?DDDBDHGGBDGIJGGF?FHC>EGGGEGGFGGHIJHEGGJIJIIIGIBCH@FGGCHIHHGFGIFHHHEF>D=@CCC@CBDDDB=>:?CDDDD<?0?:C
@4A4
CCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTTATGGGCAGGAGT
+
CCCFFFFFHHHHHJJJJIJJJJIJJIJJJJJJJJJJJJJJJJJJJJJJJIJHGIJJJJJJIHHFFFFDDDDDDDDCCCCCDDDD5<9@DDCDDDBCDDBD?
@4A5
CTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGGTTATGGGC
+
@C<DFDDDFH?DFCBGGGCGHGBGBHDGGHIJAEHICEF@ADEECDHGEGBA=FH@@=DGGIHHHGE4=>=ABBA?<@B@BCCCDDCCBD?<&5?CDDDD?
@4A6
CGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCT
+
CCCFFFFFHHHHHJJJJJJIIJHHJIJJJJJGHIIJJJJFHIJJJIIJJIJJJJJJJJJJJJJJJJHGHHHHFFFFDDDDDDDDDDDDDDDDDCCDDDBDA
@4A7
ACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGG
+
CC@FFFFFGHDHHGHIIJJDIIJJHIIIIHGHHJJBHJIJIJGHIIJFGIIIGIIIJBHH>BCCCDBDDCCDDDDCDCDDEDCCCBDDDDDDDDD@CDCEC
@4A8
GGAAAGTGAAATTTCAACCACAGCAGATGACTGCAGTTCAGAGGTAAATGGTTGCAGTTTTGTGATGAGAACAGGAAAGCCTACAAATTTATTAAGGGA
+
@@@FFFDDFHHHHJGIJJJJJGIJIJFHIJJJJJIJIHIIJIHIFHGEGII?DHHIIIHIIJ@FHEGEHGIGIIHGHHHFFFFFEEEDEECDDEDDDDD
@4A9
CTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTAC
+
@@@DDDBDHGHHGFGGEEEHGHIGIIGHIGGGIG?GHJIGEHGCHIGCHJIJHGGEEHFDFFFD?CCCCCCDCCDA@CCDDDDD???@C:CCCDDD?@BDC
@4AA
CGGGAAGGACCCACATACCAACGGCGAGGATCACTTCAGCTCTGGCAGTTTTTGGTAGCTCTTCTGGATGACCCTTCAAATTCTCATTTTATTGCCTGGAC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJIJIJJJJIJJJJJIHHHHFFFFFFDDACDDDDDDDDDDCDDDDDDDDDDDDDDDDDEEEEEDDDDDDDDD?A
@4AB
TGATGGCAGTGTGTTCACACTTTGTCAGATGAGAAATGGGATGTTATTAACTGGAGGAGGGAAAGACAGAAAAATAATTCTGTGGGATCATGATCTGAATC
+
@@CDDFFFFHHFFGIJIIJJJJIIHIIIJDGHHICHGGGIIIJJHFIIIJDEGGBGGAFEHGIFGIEHFHHGFFFFFEEDEE@CDDBDDDDDDDDDDDDCC
@4AC
CCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCT
+
CCCFFFFFHHGHGIIIJJJJIIIIIJJJJJJIJIGIIJDHIIIFIIJIJIGIJIIJJGIEIIEGIJHGGFFHFDFFFEEECEDCCCBDCDDDDDDBBDDD
@4AD
CAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCC
+
@@@FDDDDFHHHBEC@BEAFBGIICD9CFEEGGEHH<DFHIIC*/BFH;B8=<C=FHIIIIC>EHB>D2@>A@A@;>>@D?B855,5:>>4>CDCDC:AA
@4AE
TTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGC
+
CCCFFFFFHHHHHJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIIHHHHHFFFFFFECCEEEDDDDDDDDDDDDDDDDDDDDD
@4AF
ATTCAGAAATTTTTTCTTAAATAGCATTTATAAGTCCAGAGATGAAGCAAACAACAGTGGAGTCATAAATGAAAGCTTTGAAGGTGAAGATGGCGATGTG
+
@CCFFDFFDFFHHIEIJJIIGJEHJGGIHGGGGC9CFB@38:9BFG@GHIH;F8?2B=CFDFHECHGHGHGGIGHEHHECB7@D7>CC@@:AC?B=@?<:
@4AG
AGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGC
+
@CCFFFFFGHFHHIIIIIHGJJJJJJJJIJJJJJJJJJIIJJJJJJIJJIFIJIHDHHFFFDDDDDDDDDDDDBDDDBDDDDDDDDDDDDDDDDDDDDDDD
@4AH
GTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAAC
+
CCCFFFFFHHHHHJJJJJHJJJJJJJJJJJJJJJHIJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHHHFFFFFFDEEDDDDDDDDDDEDEEDEDDDDDD
@4AI
GAGAAGATGATGGTTAAGAGGAGAGACTACTTGGACCTTGCGGCGTCCACTCCATCTGACTCCCTGATTTATG
+
CCCFFFFFHHHGGGHIJJIIJJJIJJJJJJJJJJJJJJJJJJJJJJJJJHHHHHFFFFFFEEEDEDDDDEDED
@4AJ
GGGGAAATAGTTTATTTCATTGCATCAGTAGTAGTACTATTTAATTATGAGGAGAGAACTCAGCGACACTACCTGGGCCATACAGACTGTGTGAAATGGTT
+
@@@FFFFFFFBDFHIGGIJGJJFIGIIEACHFGGBEHFGIIGHIJIIIJGIGDGGEIIFFGIIGG@BGHICAHHHHFFFDEEEEEDDDDCCA<CDCDCD3>
@4AK
CCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTGAGTTGCTA
+
??;A?B2=A:ADD@:A?C1FE8<CF81:?D9*1:DD>9??;DDC>8DDDEBCAB>C@.@==C3;@A)7;=@DDD@>>A@?:,',559(9::>>++4((4
@4AL
AAGAAGGAAAAGAAAAAAGAAAAGCACAAAAGGAAAGAGGAAGTGGAAGAGAATAAAAAAAGCAAAGCCAAGGAACCTCCTCCTAAAAAGACGAAGAAAA
+
CCCFFFFDHGHHGIIJJJGIIJJIJIJJJJJJIJJJJJJJJJJJJIIIJGIIGJJIJJIFDDDDDDDCDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDD
@4AM
GAAATCATAAAGACAGCCAGTTCGAAACTGATATAGTACAACGAATGGAACAAGAAACACAAAGAAAGTTAGAACAACTCCGGGCAGAGCTGGATGAGATG
+
@@<DDADD?FHFFG;AGD>F<CAFBBB@EFEF?EFFIECB?GB;BFFFEFIGCA>@FCF@CGHEEAA?=??ACDEEDBA>CB>B=8=@BCCCC8CCCCCCC
@4AN
GAGGCCCTCCAACCCCCCCACACCATCCAGCACGCCAGTGTCCCCACTGCATCATGCATCTCCAAACTCAACTCATACACCGAAACCTGACCGGGCCTTCC
+
@CCFFFFFHHHGHIJJJJJJIJJJJJJJJJJJJEHIJJGHAEHGFFFFDDEEEEEDDDEDDDDDDDDDDDDDDDDDDDDDDDDDDDBDDCDDDDDDDBDDD
@4AO
CGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCG
+
CCCFFFFFHHHGHIJJJJIJFHIIJJJFJGIIJJJJJJIJJIJJJHHHFFFFEEEEEEEDCDDDDDDDDDDDDDDDBDDBDDDDDDDDDD@CDEDDDDDDB
@4AP
TATACCAGTCCACGGCTAGTGAAGATTGGAGACTTTGGACTCGCCAGAGACATCTATAAAAATGATTACTATAGAAA
+
35(-864;))2)=8((2:268;81):=>>8)1(=8).0=)))((---(3)<5>1==>;)6=><>=>?=????;?>>=
@4AQ
TCAGTGGGCGTAAGTCGGGACAGTGCTTAATGTGCGGCACAGGAACTGCAGCTACTGTGGGGAAAAGAACCGGTATAATGGCAAGCCCCCCGGCTTCGTT
+
00(22).(--(0-(2)29((((()).>=)0)).0)(((''.).6((..6)<.:))8.).(3,3'630(,((,&&&((((,(2(8-(+(&06508-&()(+
@4AR
TAACTGTCCAAAAGCCATGAAGAGATTAATGGCAGAGTGCCTCAAAAAGAAAAGAGATGAGAGACCACTCTTTCCCCAAATTCTCGCCTCTATTGAGCTGC
+
@@@BBDDAHFHDDAHJHIIEFFIBCEEGHEHGBFGDD9CCFEIIHIIGHHHGGEBFBBFFEGGIIGCHCHHGHACEFEAACEEEDBB>B=CDDD:5ACCC?
@4AS
GCTTGCTCTTCATGGGCGCTGGCTCCTTCTTGCTCACATTGCTGTTGCTGCTATTATTTTTCTTCGTCTTTTTAGGAGGAGGTTCCTTGGCTTTGCTTTTT
+
?@@DD3?DDHDAFD<CFGHGIEBGBFBCC>GCHIIIBHEHGID@BDGGHGGHFHGHGGGGHCEEDH=AE?A@@BDECA?ABB5=A@CCCCCC?CCCCCCCC
@4AT
CTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACC
+
@@@FDFDBFHHFFHIJDGIIIIJJGHGGJIJIJIIIIJJJIIEIFJJIIJEGIIIFGFFEFFFEC@CCE@@CC@@AA@A?BDDBDBDCCD>CCCDCCCD@C
@4AU
GGGAGACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTT
+
@@CDFFFFHHHHHJJIIIIJJIIFHIDGIDHHJHIHIGIJJJIJJHHHFFFDDDDDDDDDEEDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDCCED
@4AV
TTCAAATTCTCATTTTATTGCCTGGACTGGTCGAGGCATGGAATTTAAACTGATTGAGCCTGAAGAGGTGGCCCGACGTTGGGGCATTCAGAAAAACAGGC
+
CCCFFFFFHHHHHJJJJJJIJJJJJJJJJJHHIJJJJJJJJJJJJJJJJIIJJJJIJJJJJJIIJJJHECHFFFDDDDDDDDDDDDDDDEDDDDDDDDDDD
@4AW
TTTTAGGACAGCAAATTAATGACTTTACCCTTCCTGATGTGAACCTTATTGGGGAGCATTCTGATGCAGCAGAGCTTGGAAGGATGCTTCAGCTCATCTT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJGJJJJJJJIIJJJJJJJIJJJIJJJJJJJJJHHHHFFFFFEEEDDDDDDEDDDDDDDDDDD
@4AX
CCTGTCTCCAGATCTCAGTAAGGTACGGAGTAACTGTCCAAAAGCCATGAAGAGATTAATGGCAGAGTGCCTCAAAAAGAAAAGAGATGAGAGACCACTCT
+
CCCFFFFFHHHHHJJJJJJJJJJHIIJJJJEGHIIJJJJJJJJJJJJIJJIIJJIIJJIJJIJJJAG@DHGHHHHHHFFFEEEEDDCCDDDDDDDDDDDDD
@4AY
CCAATATGAAGGAGGTACCTCTGTTCAGGCTACGTCACTTCCCTTGTGGGAATGTCAATTACGGCTACCAGCAACAGGGCTTGCCCTTAGAAGCCGCTACT
+
CC@FDFFFHGHHGIFCEHHHJIIDHIJJJIJIIIGGIIJIIIIJJJFHIJIHJJFGIIJJJIIJJGFFHHFFFFFECDDDDDDDDDDDCCACCCDBDDDDC
@4AZ
CTTATATGGAGCAAAACTACTGTAGAGCCCACACCTGGGAAAGGACCTAAAGGGGTATATCAAATCAGCAAACAAATCAAAGCTCATGATGGCAGTGTGTT
+
?;?B;BDDHAHFDG3AGFFDHHBEFGGHFDFFHIEDHHHECGBBBDFFGGCDA(<@;CHHAGIEH>HHHEEE@DEACCCCCCCCCCCACC@CC?@?C;>?A
@4B0
CCAGTGCCGAGTTACGCTTCCTCGACGCCACTTCATGTTCCAGTGCCTCGAGCGCTCAGGATGGAGGAAGACTCGATCCGCCTGCCTGCGCACCTGCAATG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJHIIJIJJJHHFFDDDEDCDDDCDDDDDDDCDDDDDDBDDDDDDDCDDDDDDDDDDDDD
@4B1
CAAAAATTCACCGCAGTGCATCAGAACCCTCCTTGAATCGGGCTGGTTTCCAAACAGAGGATTTTAGGCTATATGCTTGTGCTTCTCCAAAAACACCCATC
+
@<@;DDDD<FFHD8AFEBG<EH@B<GCHF>F?;?FGEGH@F6?@F;@7.)@GHIEC=;=?.;;?DEC(;3;.(;@>;35=AACCCCACC?CB8>8??@?33
@4B2
GGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATAC
+
CCCFFFFFHHHHHJIJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJIJIIHHFFFFEEEEEEEDDDDDDDDDBDDDDDDDDDDDCDDDED
@4B3
CAGCAAACTTCCATATCCTGTTGCCAAGTCTGGGAAGCGAGCTCTAGCTGGAGGCCCAGCCCCTACTGAAAAGACACCCCACTCAGGAGCTCAACTTGGGG
+
(-;159488)9:@)6))6<=).2)).2().96):>913--0(5=?81>1<7(<((-(-(.-35760.69;(.:(=;>;''8'302(,:(2(+(5((++(25
@4B4
GGAGAAGATGATGGTTAAGAGGAGAGACTACTTGGACCTTGCGGCGTCCACTCCATCTGACTCCCTGATTTATGACGACGGCCTCTCAGAGGAGGAGACAC
+
@@?DDFFDHGBHHHCFGGHBIGCHHGHIGGIGGIIIGGIIGGIIIIAEHHHHHHFFEFFFEEEEDDDCCDEDDDDDDDDDDDDBBCDDCAA?AD@@B?BDD
@4B5
CTGGGCCGCGTGGTGCACATCATCCAGTCACGGGAGCCCTCCCTGAAGAATTCCAACCCCGACGAGATTGAAATCGACTTTGAGACCCTGAAGCCGTCCAC
+
@@@?DDD8C?CFAGEEGEHGGCGDGGIDDFE@BBGGGIIIGCEC?AEECEEDCCDCCC@BBBB@BBBBCCCCC:4+<<<BCCC@B>BBCCCC:A?><<>B>
@4B6
CACAACACCATGGTTGGCAGTGCGGCCAGCCAAAGCTTTCCCCCTCCTCTGATGATTAAACAGGAACCCAGAGATTTTGCATATGACTCAGGTAGGCCTGC
+
CCCFFFFFHHHHHGHJJJJIHHJIIIJJJJJJJJJJJJJJJJJJJJJJJJJHHHHHHHFFFFEDEEEDDDDDDDDDDDDDEEDDEECCCDDDCCCDDDDDB
@4B7
CAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCC
+
CCCFFFFFHHGHHJJDIJJJJJIJJJJJJJJIIIJJJIJJJIJJJJJJJIJJJJHHHHHFFFFFFFEEEEDDDDCDDDDDDDDDDDBBDDDDDDDDDDD
@4B8
AGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACC
+
CCCFFFFFHHHHHJJJJJIJJJJJJIIJJJJJJGIIJJHJJJJJJJIIJJIIHHHFFFFFE@CEEEEDDDDDDDDDDDDDDDDDDDDDDDDDDDEDDDDDD
@4B9
CCTGTAACTCCTTTCCTCCTTTGCCGACGATGCCAAGGGAAGGACGTCCTATGTACCAACGCCAGATGTCTGAGCCAAACATCCCCTTCCCACCACAAGGC
+
CCCFFFFFHHGHGGIEBGIIIHIIIIIIIIIGIGIIIGGIIBHIIIA<GHIEHHFAHFEEFDDDBDDDEDC:@CC?CCCBADDDDBDDCDD<ABD?BBB?A
@4BA
CTAAACACTCAGAAGCGCAGGAAATAGACACCGGCTGAACTGTCCTGCCCGCCCGCGACCTTGGCGTGAACGCCCTACCATCCCTACGCATCCTTTACAT
+
(8-(())<).2@))).(2(2(-6@@)=.)))--((7=(.<?)))):=).(;'-'''''3;&((((&)&+(((08::22:(8(((((+&0+(0(++++(+(
@4BB
AAATCTTTAAAGCAAGAGAAAGAACAAGTTTCATTGAGATGTAGAGAGCTAGAAATCATTATTAACCACAACAGGGCAGAAAATGTACAGTCATGTGATAC
+
CCCFDDFFFHHHHGIEHIGGJJHIIIJJHGGGDHII@DCGH<FI@EHIGGIIHJIIJIIGGGCHGCGIDGGEEGGBEHDFFFECEDEDADCCCECACDEFD
@4BC
TTTCAAAGGCTAAGAATCAGATTTTAAAATTGGATTTTTGACAGGACTTGAGGGAAAAAGCTGCTTCTCTTTGAATATTTGTTATATCCCACTGTGGTCTC
+
075((9)))(3@:)8.))).<).2))))2)9))1@=))2-(6)0-6(9.)96)--9()(-.))).)))).:3))).)).))..((...(((,,4-((,:53
@4BD
GTGGAATTCTCCTTAAAAAACAGCATGTTCTAGAAAAGCCATGCTTTGGAGGTGCTGTAGGCTTGCAGCCAATTTACTGGAGCAGGGATGACGTAGCCC
+
@B@FDFFFHHHHGIIJIJJJJJIJJIJJJJIIJHIJJJJJJJJJJJIJJIJJFGIIJGIIIJJIIGHHHGHFFFFFFEEEACCDDDDDCDCDDDDDDDD
@4BE
GGCGGCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGG
+
:+=++0)?;<)))<<=A1*:*7?<4?=??<)==A*7**07<A:'.(=--6>3)..6>>>;(6=59==''(+8;;8(3;??;1:=8(+3;:8(2189;;0+(
@4BF
TACAAGTACCCTTCTGACATCTCCTACATGCCTTCCTACCATGCCCACCAGCAGAAGGTGAACTTTGTCCCTCCCCATCCATCCTCCATGCCTGTCACTTC
+
?@@DDDDDHFFH>FHHGGIIF<FBCB@GBAFEHIIGIII@D@BFE;GGDDGIGIIGGG)8BFEGG>@7@DGEGHHEEDEEECA@@CCCA>CCC>,::AACC
@4BG
TAAGCAGAATCAATTAATTTTGGAAATTTCAAAGCTAAAAGATTTACAGCAGTCTCTTGTAAATTCAAAGTCAGAAGAAATGACTCTTCAAATCAATGAAC
+
@@@DFDDDFHFDHGIIHJIHIJJGGIJJCHGHIHIHIIJGIIFHGGGHGBFIBBFAGHGDDEHIJIIJIGGGEGGIDHGGFEEEFGFEFFFFFDEECECDD
@4BH
CCACATCATGGTCTCTGTCTCCCCGCCTGAAGAGCACGCCATGCCCATTGGGAGAATAGCAGACTGTAGACTGCTTTGGGATTACGTCTATCAGTTGCTTT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJIIIJJJJHHHGHFFDFFFDEEDEEDDDDDDDDDDDDDDEDDEEEDDDDD
@4BI
CAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCC
+
CCCFFFFDHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJHHJJJJJIJJJJJJJHHHFF@DFFEEEDDDDDDDDDDDDDDDDDDDDDDDDDDDCDDDDD
@4BJ
ATGACATCTCCTGTGACTCTCACCTCTCAGACAACTAAGACAGATGACCCCCAATTGAAAAGAGAAATAAGGTTAATGAAAAACAGAGAAGCTGCTCG
+
CC@FDFDFHHHFHHIIIGJJJJJJIJIJJJIIIJIJJJJJJJJJIJJJJJJJJJJJJIGGGGEHGIIIHFFHCEBBFFFDFEEDDDDDDDDDDDDDDD
@4BK
GATTTTTCAAAAGCAGATTCAGGTGTTCATTTATGTGTTATTGATGACTCCAATGAGCATATGCTTACTGTATGGGACTGGCAGAGGAAAGCAAAAGGAGC
+
CBCFFFFFHHHHHJJIJIJJJJJCFHIIJJJJJJJFIIIJJIJJJJJJJJJJJJIJJJIIJIJJIJJJJJBGGIJJIJIJHHHGFFFDEEEEECDDDDDD@
@4BL
GTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGAT
+
@@CDFFFFHHGHHIIGIG@EACEHIIIJJJIIIJIIIIIJJFEGGIGIJHIJJJJIJIIIIJJGHHHHHDEFDEDEEECECCA?CABDBDDDDDDDDCCC@
@4BM
ATTGACAGCAACACGTTTGAAATGAATGGCAAAGCTCTCCTGCTGCTGACCAAAGAGGACTTTCGCTATCGATCTCCTCATTCAGGTGATGTGCTCTATG
+
CCCFFFFFGGGHGBHJBHEHHIIGFGJGIIJJIIJJIIJJJGIGIJJJJJJJJGGEII>GHIIGDHFFHFDFDEBCCDDCCCDED@5>>@CCCDDDCDDE
@4BN
CCATGCTGGACCTTCTGCACGTGGCTCGGGACATTGCCTGTGGCTGTCAGTATTTGGAGGAAAACCACTTCATCCACCGAGACATTGCTGCCAGAAACTGC
+
@CCFFFFFFGHHGGIJIJIJJEEGEHHGIJHHEIIJJJGGFHJIEG=FHI;CFHHGGCGEEAHDEFBBDDEEEEDDDDDDDDBDCCDCCDDBDCACDCCCC
@4BO
CACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATG
+
=>=1++++2<>7C9,222+3A<=A3<?>C==<A@4@71?;:;A:=A5;A9A<A<>7AA;;))8.>=A)==A))))67>@>(.5;;5;;>(;;=33:;=9;(
@4BP
AGGAAAGCCTACAAATTTATTAAGGGAAGAAGAATTTGGTGTTGATGATTCTTATTCTGAACAAGGAGCACAAGACAGTCCGACTCATCTAGAGATGATGG
+
@C@DFFFFHHHFFHIJJIIJJJJJJIJJIHIIIIIJIGH?DHGIJIIJJJJJJIGIJJJJJJIJIGEHIHIIHFHFEEFDFDDDDDCDDDDDDDCCDCCDD
@4BQ
CTGGGGGGTCTCTGCGGACGAATGCTGAATTGTTAGCCAAAGATTGAAACAGGATATGAGGAATCCTGGGCCTTCCAGTGTGCACTTGAGCGGGGGTGGCG
+
7((:-((,,0+(3:6&)1&&&&+5+26((++(+(+(5(2/+(3((+++66(((++:22(265((((+(((+82((+6(+++(((+((+(++&0&&&)0-7&
@4BR
AGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACC
+
@@@FFFFFHHDFHJBHGDEGIIGIGGGJIIIGIIIIJIJIIDHGGGHIIGGIGGGCHGHIJJJIJHHCEFFFFECDCC.;>CCDD<CCCDDDBB9ACCDDA
@4BS
TTTGAAATGAATGGCAAAGCTCTCCTGCTGCTGACCAAAGAGGACTTTCGCTATCGATCTCCTCATTCAGGTGATGTGCTCTATGAACTCCTTCAGCATAT
+
CCCFFFFFHHHGHIGEHGGHGGIJFGGIGHGIIJJJJJIIGJJDGHIGGIGHGGGGDDFCEHGECDFHFHHEDFCFDEFDEDDEEEEDCDDDDDDDDDDDC
@4BT
GTTACAAATTACAAGATAAAACTTGAAATGTTAGAAAAAGAAAAGAATGCTGTGTTAGACAGAATGGCTGAATCACAAGAAGCTGAATTAGAGAGGCTG
+
@B@FFFFFHHHHHJJJJIJJJIIIJJJJJJHIIJJJJJJIJJIIJJJJJJJJHIIIIJJIHIJGGJIIJJJIJGHHEHGFFFFFDCCEEDC>CCDDDDB
@4BU
AAGTGGAACTGGGGTGGAAGGGTAGCATCTGTCTTGTTAGTTTTGGAGTTGGTGGAGGGGGGGTTGGGATACTTCTTGGTGTATTTATTGGGGTGGGGCTG
+
((-(())))))2(((((():(1:.()))0))))))).)))0)))0())))/.(((((-',')&&&)&&(+((((((+(+((((++((((((()&)&&&&&&
@4BV
CCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATAC
+
@CCFDFDFHHHHHIJJIGIJIJJJJJIIGIIIJJJIIJJJGDIIIIJJJJJJJJIJJGHFGHGFDFFEECECEEDEDDCDDDDDC?CCDDDDB@BBDDDD
@4BW
GAAAAAAAGAAAAGCACAAAGGGTAAGAGGAAGTGGAAGAGAATAAAAAAAGCAAAGCCAAGGAACCTCCTCCTAAAAAGACGAAGAAAAATAATAGC
+
5(55=?(5;(.2.).@1<;1))(().<)3(6=7<18.))069.)9))/35''(9690(((,(9(-6((7;558(86</2&+(&&06977/8(+6:26:
@4BX
ACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACT
+
@@@DDDDDDDHHFEGGIEDHGHGGCFCFGFEGIIIGGIIIIIIIEHIIIIGGIGHHIIHGHCEE@GHFEEHHDBBBD@BBCDEEEAADDDCDACDCC@CCA
@4BY
CCACGACCCAGTGTATGAACACAACACCATGGTTGGCAGTGCGGCCAGCCAAAGCTTTCCCCCTCCTCTGATGATTAAACAGGAACCCAGAGATTTTGCAT
+
CCCFFFFFHHHHHHGHIJJJGJJIFIJJJJJJIJIIIJGFHEHJJJJIIHHHEDFFFFEEEEDDDBCCCCCDDDDDEDCCDDBDDDDDDDDDCDDDDDDED
@4BZ
TTTCGCCGCCAGCTTTCTGAACCCTGTAACTCCTTTCCTCCTTTGCCGACGATGCCAAGGGAAGGACGTCCTATGTACCAACGCCAGATGTCTGAGCCAA
+
@@@DDDD<<?<<DAGE@E<F>F881:?D?DFCFCFFI<<@BD@4=@9FFBEF??;?BA@@7@9;?BBB288?AAA4>3:@B7255>5?>>+::>B>:?99
@4C0
GTGAAATGCCTGGAAAACCGAGTTGCAGTCCTGGAAAATCAAAATAAAACTCTAATAGAAGAGTTAAAAACTTTGAAGGATCTTTATTCCAATAAAAGTGT
+
???BDDFFHHHFBEBHIEFHGHAFEHIGIJEGGG@FGEGABDCBGCHCGIEDHICEGE@ADFHA@EHEGCHHHHHFFFD@D@ACC>CC>CCA@@C>>>CCC
@4C1
ATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTAT
+
@@@DDDFDHFHHFBHBHIHIGCCECHGIIEHFGHIIGBGBFADFDEGGAHGBHIF;CHBAFA@:9=<AAAD@CCCCDDC>CDCC>89A<CDDC@2>A+:C>
@4C2
GCATATTCTGAAGCAGAGGAAACCTCGGATTCTTTTTTCACCATTCTTCCACCCTGGAAACTCTATACACACACAGCCGGAGGTCATACTGCATCAGAACC
+
CCCFFFFFHHGHHJJJIJJEHIJIJJJJJJJIJJJJJJJJJJIJJJJIIJJJJIJJJJJJJIJIHHGHHHFDFDDBDDDDDDD?ACDEDDEDDDDDDDDDD
@4C3
GAGGATTTTAGTCTATATGCTTGTGCTTCTCCAAAAACACCCATCCAGGCAGGGGGATATGGAGAATTTGCAGCCTTCAAGTAGCCACCATCATGGCAGC
+
@@@DDEFFHDHFHIJGHIJJIJIIIGGGHHJJJJJJIJJJJJIIJJIJJGDHIJJD=EHHHFFFFFEEEEDE>CBDDDDDDDCCCDDDBBDDDDDCDCDD
@4C4
GACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTG
+
@@@DDDDDFHHHAGG@HGHIAFEC;FFGG@FGICGHHGHECGIII@@=C(=CFEGGHEHHEEHHEEEEDDCCACCCCCCBBBB9BBBBAC@CCC<AB?8<A
@4C5
TATAAACCTAGCTAAGGCCATCCCCCTATGAACAAGCGCATATATTATAAACTTACACTCTAAAATTAAAAATGCACTAACCCACTACTTACCATAACAA
+
(--:(=)9=;)9):))))289<(83(--:)))2)))10(</-)).)0)0))))))/))..).<6:).;>1:>0).)).;9;976;7(6170,5;(5;(,(
@4C6
CGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCG
+
CCCFFFFFHHHHHJJJJHIJGHIHJIJJJJJJJJJIIJJIIJJIJGHHFFFFEEEEEEEDDDDDDDDBDDDDDDDDDDDBBDDDDDDDDDDDDEDDDDDDD
@4C7
CCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGC
+
BCCFFDEFHHHHHJJJJIJJJIJJJIIIJJIJIIIJJJJJJJJJJJJJJJJJJIIJJJIJJJJJJFHHHHHHFFFFFFEDDDDDDDDDEEEDDEDEDCDD
@4C8
CTGTGCCATGCTGCCAGTTAAGTGGATGCCCCCAGAGGCCTTCATGGAAGGAATATTCACTTCTAAAACAGACACATGGTCCTTTGGAGTGCTGCTATGGG
+
@==ADB?DFDD<FH@EHFEF?A3<???FGF@E?FD?DBGIIIHGCGI3BB?BHCCCHA>=>DC=C;@CGCHHEF;?7?;;6;;6@C?AC(,5(::,>AC@<
@4C9
CGGAGAAACGGGGAGAGGTGGGGAGGGGCGTGCCAGCACTGGCCACCGCTTTCAGCACCCGTCCCCCGTGGAGCTACCAGGCCAACCCCTGCTCATGCCCC
+
-(;8=0(.)(-8((:(=(:81(((-07'59?36=;:8;93-2(;;<02&&&2+(2(+22()&2&&(0)))&+(+((+8:<8(((+(&&&22((42+2((+(
@4CA
TACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJHHFDBDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDCCDDE
@4CB
CTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTC
+
@@@DDDDDDF?CFEICFGEG>FDEHEGGH@E;C;?FHGIH<<)?BFDBFCFDGICCG@HGGFIIEGACHEEB?C=CCC>CCCC>C>CC??<9?:A:49:>C
@4CC
GAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCAC
+
@@CFFFFFGFFGHJIIGIIJJJJJJJJIIIJGGHHIEHGIJIJHGIIFEBEGGAEHEDEEEECC>CCDCDACDD?BDDDDDDDDDDDDDDCB>CDCADC
@4CD
GTACCAACGCCAGATGTCTGAGCCAAACATCCCCTTCCCACCACAAGGCTTTAAGCAGGAGTACCACGACCCAGTGTATGAACACAACACCATGGTTGGC
+
@?BDDFFFHHHHHJJJIIJJJJIJIJJJJIIIJJIIJJJJJJJIIGIJJIJJJIHGGIJHH>AHEFFFDDDDDD>CCCDEDECDCDDDDDDDDDDCABDD
@4CE
ACAATGGAAGAGTGGAGGTGGGGGGGGCGTGGAGATGGTGAGTGGGGGGGGGGGTGGGGTATTAGTGGGGGAAGAGGGGGGGGGGGGGGGAGGGGGTGAGG
+
+++4+++++++3,2+++2+++@)003&&&)05(((+3((+(((+(())))0580&&&&&&&((((((((&&&&((+())&)))&0&)00&&)&&0)&)(((
@4CF
GTCCAAGCCTAAAAACCTTGCTCCTTTACAAGAGAGTCAGGAGTCTTACACAACTGGGACTCCCAAAGCAACATCTTCTCACCAGGGCCTTGGAAGCACTT
+
?@;D;AADF?AFF@AF;AC:CHDGBE>9FBB9??)1*1:?9*:B?BD<<B<?/78..(@28==C77C7))=(67)).;;36(6-((,,,55>?B:?B99:>
@4CG
GGTCGTACAAACTGCATCAGGAGATATGCAAACATATCAGATCCGAACTACACCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATGACATCTCCTGTG
+
??:AA@BDF?A;A?>?F<FA?3AAAFGCHH@<EHDH*1?CHBFGB??DHAF>BCFGA;=FHGIC@D@EACHE@E?BDDC@;>A6;@>>;@;:C:>@:A:@
@4CH
CATTGCCAAAAATTCACCGCAGTGCATCAGAACCCTCCTTGAATCGGGCTGGTTTCCAAACAGAGGATTTTAGTCTATATGCTTGTGCTTCTCCAAAAAC
+
@@<DDFFFGDFHGC>FGEHIIIEDF@FHIIGGHEHICCHHGHG@FHGI@EGE@E@E>EE>=;?@DD>A;ACD9@C;5-;A:;ADCA:@CCC>AA:?C?<5
@4CI
AGGAAAGGACTGTAGAGCTAATGTTTACCTTCTTCCGACCGGGGAAATAGTTTATTTCATTGCATCAGTAGTAGTACTATTTAATTATGAGGAGAGAACTC
+
@@<ADD;D?FHFHIB<EHHDBHGHGG@FHCFGEGGIGIFGGGEFFEDEC==AHCHFAB:?BE;@6>AC66@35>>B>>@BDC@ACA5@;@@?CBB7<CCCC
@4CJ
ATTATGCAAAAGGTGGCTGGAGAGAGATATGTCTACAAGTTTGTGTGTGATCCAGAAGCCCTTTTCTCCATGGCCTTTCCAGATAATCAGCGTCCACTGCT
+
@CCFFFFFHAFFDCCF>FGGIG;FHGIIIIIDHGICBFADHICHDDHHHI<BDDEIIIGIIIIIIEH;CEHCEFFFFFCD7>ACECECC5@@BCBBCCCCC
@4CK
GGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAAT
+
@@@DDDDDDDDACE@FEDIFFHHEDHI@?F@GGFGAHEIEHIHGBBDHEHIEGBFGAGCHGA@DEBEHEDECCA>;CC>>A>;@AAC@<CCC>:>ACCCD
@4CL
CTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTC
+
CCCFFFFFHHHHHJJIJJJEHIJJJJJIIIJJJJJJJJJJJJJJJJJJJJJJHHHHHHFFFFFFFEEEDEDD@CDDDDDDABDDDDDDDDDDCCDDDDDDD
@4CM
AGAAGATTATCAGAAAAAGAAAGAAGACTTCACAATGCAAATTAGTTTCTTGCAAGAGAAAATTAAAGTATATGAAATGGAACAAGATAAAAAAGTAGAA
+
CCCFFFFFHHGHHGJJJJJJJJJJJJJJJJJJJJIJJJJJJJIJJFHIJJJJJJIJJJJJJJJJJJJJAGHIIJJJJIHHHHFFEFFDEEEEEDD@CDDD
@4CN
GCCCAGTGGCTCAAGTGGGCTGAAAATGAGTTTTCTTTAAGGCCAATTGACAGCAACACGTTTGAAATGAATGGCAAAGCTCTCCTGCTGCTGACCAA
+
@@?DBDBDCFHFHGA:A3;BF@?CFHIGGH:CBGIGGD<CHGHEBDGHHGCE<DABCCBFGAFGIIIECEHAEE>B@67;>@CACCA@A:ACCCCCA?
@4CO
GGAAGAGAATAAAAAAAGCAAAGCCAAGGAACCTCCTCCTAAAAAGACGAAGAAAAATAATAGCAGCAACAGCAATGTGAGCAAGAAGGAGCCAGCGCCC
+
@@@DFFFFFHHGHJJIIJJIJGIJJJJJGIJIJJJJIJGIJJJJJJGJJJIHHHHFFFFFEEDEEEBDDDDDDDDDDCDEDDDDDDCCBDD@BDDDDDDD
@4CP
AGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACT
+
<:?DBBADHABHHIE>FHGHGGIGDHBHBHGIGG@DGGGECGFGEGGHGGGEG@HG7@EGGAEHF7??EDEFD>@CEACCCCC==ABBCBBBCCCB??B
@4CQ
TATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATC
+
CCCFFFFFFHDFHIJJJJIJJIJJJJJJJJJJJJJIJJIJJJJJJJIJIJIJIIJJJJJJJJJIHHHHHFFFFFFEEDEEEDDDDDDDDDDDCDDDDDED
@4CR
CACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGC
+
@@@FFDDADHGDHGGIIJGGIJIJJIJJJJJIJJJIIJIIJJJIIIJJJJJIJJJJJJGIGHGGHHHEHHFFFFFDDACCCDDDDDDDDDDDDCDDDDD
@4CS
GCAGCTACGGGCAGCAGACTGCATCAGGAGATATGCAAACATATCAGATCCGAACTACACCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATGACATCT
+
@@@FFFFFH>AHHGDGGHIGGEEHIGE>GGCDFDCBIIIGIGGGGIDHHGGGBHGEGGIIHGHFHFDDFFFEEDECDEDDCDDDDDD>CC<@CDCEDCCCC
@4CT
GCATAAAACGACCATCACCAGCTGAAAAGTCACATAATTCTTGGGAAAATTCAGATGATAGCCGTAATAAATTGTCGAAAATACCTTCAACACCCAAATT
+
8==DDDDDFFFF><F:EDFHEEEGEGFFCFBF>?BF<?DDFF<@FFFIIBFIFIF4.=@=CFFEAA<?CCDB;@;;<;@?;@@BBB@BBBAB?B<??B@A
@4CU
AGAAACCCACAGCTGCAGAGGTCTCTGTTCGAGTCCCTAGAGGGCCGGCCGTGGAAGGGGGACACGTGAATATGGCATTCTCTCAGTCCAACCCTCCTTCG
+
CCCFFFFFHHHHHJJJJJJJJHFHIJJIJJIJJIJJJJJJJJJJJJJJJJHEFFDEEDDDDDBDDDADDDDEEEDDDDDDEDDDDDACDDDDDDDDDDDDD
@4CV
TACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCT
+
<@@DD:BBF<:CFFFIEFIIIIEFE@DFFICIEFF@?DBFF>FEFIIIA@4?;?EDDDDCCCBBB@BBBEABBB?BBBBBBBBBBBBBABB<B?BB@<ABB
@4CW
CAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGC
+
CCCFFFFFGHHFHHIIJFJJJJIIJIJJJJJJJIJJGJAFGIJIJIIJJCGHHHGHHHFFFFFFDDDCDDDDDDDDDDDDDDDDDDDDDDDDCDDDDDDC
@4CX
CGATGCCAAGGGAAGGACGTCCTATGTACCAACGCCAGATGTCTGAGCCAAACATCCCCTTCCCACCACAAGGCTTTAAGCAGGAGTACCACGACCCAGTG
+
CCCFFFFFHHHHHJJIJIJIJIIIJIIGGIGIGGIJJIJJIIIIJIJJJIJIIIIJJHHGHFFFFFDDDCDAABDDDDDCDDDBDD<ACDCC?BBBDDDCD
@4CY
GACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATAT
+
CCCFFFFFHHHHHJJJJJJHHIJJJJJJJJJJJIJJJJJJJJJIIIJJJIJJJIJJJJJJJJJJJHHHFFFFFEEEEEEDDDDDDDDDDDDDDDDDEDEED
@4CZ
AAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGCAACTACAGTTATCCCCAGGTAC
+
@@@DBDDDFFHHHG?FGHGI@H>DCBEHHIIIC<DG@BFGHE<FB;FA;A@EEHHFHD?BEA;C;AC;A>C555@7:>(5<9?:4:4>:@@@CCB???+>4
@4D0
GCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJIJJJJJJJJHHHHFFFFFEEDDDDDDDDDDDDDBDDDDDDD
@4D1
CAAGAACCCGACCAAAGACCTACTTTTCATAGAATTCAGGACCAACTTCAGTTATTCAGAAATTTTTTCTTAAATAGCATTTATAAGTCCAGAGATGAAGC
+
CCCFFFDDHHGHFIJIJJIHJGJJJJJIIJJJJJJJIJIJIIIJJJJJIIJJJIJIJIJJJIIJJHHFFFFEEDEEECDCDDECDECDDDDDDDDDDDDDC
@4D2
GGTGTATATCAAATCAGCAAACAAATCAAAGCTCATGATGGCAGTGTGTTCACACTTTGTCAGATGAGAAATGGGATGTTATTAACTGGAGGAGGGAA
+
B@BDDFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJGIIHHIJJJJJJJJJHIJJIJJJJJJJJJJJJJHHHHHFFFFFFFEEDBDDDDD
@4D3
CAGAGACCTCAAGAGTAATAATATATTTCTTCATGAAGACCTCACAGTAAAAATAGGTGATTTTGGTCTAGCTACAGAGAAATCTCG
+
@@@D?DDDFFD+AC;ACGB>HFIBHB9C?9?CEF<***?E@GD*?D?9FEF<<D<D3?BF?<FB408=7@==FF@A;)7;=.=;;B9
@4D4
TGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGG
+
888DD?+AD2AD?@?<@@:F)?E8CEAEEIIIEIID*09909DDDID=;@ADICAC@CAD3=>3;?AAD;;@@>@???(,8>>>>A>A<<<<>9<>>>A>?
@4D5
CCTGACCCCGAGCAGCGGCCCCTCCGGTCCCCCCTGGACAACATGATCCGCCGCCTCTCCCCGGCTGAGAGAGCTCAGGGACCCAGGCCGCACCAGGAGA
+
CCCFFFFFHFHFHJIIHGGIJJIJJIHAGIJJJHHFFFFEDDDDDDDDDDDDBBDBDCDDDDDBDDDDDDDDDBCDDDDD?BDDABBBDDDDDDABDDDD
@4D6
CGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCC
+
CCCFFFFFHHHHHJIJIIJJJJJJJJJJJJJJIIIJJJJJJIJJJJIIJJJIJJJIHHHFFFFDDEEEEDDDDDDDDDDDDDDDDDDDDDDDDDCDDBBDD
@4D7
GCTCTATGAACTCCTTCAGCATATTCTGAAGCAGAGGAAACCTCGGATTCTTTTTTCACCATTCTTCCACCCTGGAAACTCTATACACACACAGCCGGAGG
+
@@@FFDFEHHHHFGIIGIJJJJJJJHJGIHGIIIIGGCFHFHEHGHHIIJIIJJIIGIJGIIIIGGHJCHEFFFFDEEEAEEDDFCDCDDB@DDDDBB>BD
@4D8
CGGAAGTTCACTACAGAGAGTGATGTATGGAGCTTCGGGGTGATCCTCTGGGAGATCTTCACCTATGGAAAGCAGCCATGGTTCCAACTCTCAAACACGG
+
8=@DDDDDFFFFFBA@CFBE3ACEHAFDCGIIFBEFD@GI6?8?BFBBAFCF9CEDE=@E;AAAAEDBDDD>BCCA;=A@?5>ABEA?AB::>@@>2<9@
@4D9
GGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTC
+
C@@FDFDEHHDHDIJJJJEHHIIJIJJJGIJIIEGHIIGHIIJIJJJJJJJJJGHIJIIHJIHHEHDAEEFFFDECEDCDDDB@CCD@BDDDDBBDDDADD
@4DA
CGGGGAAGGAGGTCCTGTGGCCACTCTATCCAAGCCTTCCCTAGGTGACCGCTCCAAAATTTCCAAGGACGTTTATGAGAACTTCCGTCAGTGGCAGCGTT
+
@;@DBDD?DFFD<ADC<CGGHGIIGD:D9F9?FHIEDDG;D9?FD99CC@AF;BBAEEAEED;@CDE?6;>BBC;C:>:>@CA@::5AB85@>C8?<?B22
@4DB
GGAAGACCTGGCTTACATGAACCACATCATGGTCTCTGTCTCCCCGCCTGAAGAGCACGCCATGCCCATTGGGAGAATAGCAGACTGTAGACTGCTTTGGG
+
CCCFFFFFHHHHHJJJJJIJIJJJJJJIJJJJIJJIJJHHJJIJIIIJJJJJJJJJJJJJHGHGFFFEFEEED??@BCDDDDDDDDDDEDDDDDDDDDDDD
@4DC
ACTAAATGAAGCTTTGTCAGCAAAGGAAGAAATTGCTCAAAGATGCCATGAACTGGATATGCAGGTTGCAGCATTGCAGGAAGAGAAAAGTAGTTTGTTGG
+
+1+A:?DAC<DDBEE:<C?<AC3ADD@E9EE9?EE<?4C@D*1*0??DB<DE<*933BDDC:BE<BCACD@)==)7=?3;5.?@@(>(;>;>>;;>A(59<
@4DD
TGCGGAAGAAAAGGAAACCTCAAGCTGAGAAAGTTGATGTGATTGCCGGCTCCTCCAAGATGAAGGGCTTCTCGTCCTCAGAGTCGGAG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJIIIJJJGHIIJJGIIJJJJJJJIIJJJJJJJHHHHHFFFFDEDEEDDDDDDDDDDDCDDDDD
@4DE
ACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGT
+
@@@DDAFF<FDFHEDFHIGB@FCFGG@DGEHEGGIIECHIIGIG@CBHBEGAAAG@DGH=C>ACB>DCB;?CC@ACCDB@DBBDDBBDCDCCCBBBDDDDC
@4DF
CGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGG
+
CCBFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHHHFFFFDCEEEEEDDDACDDDDDDDDDDDDDDDDD
@4DG
CCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTAT
+
@@@ADD>DHHHB?B><??B:@G6ECGCG;?@FDHDACFG8/?FG>GG>E;CEHCB;BD@CAB;@ACC@CCC;?B9?@;??8??:>CDC8<CBBBBBCCCCC
@4DH
TGTGAAGTGAGGGTTCTGGCAGGGTTGAGAGAAAAAAAGAGGCCAAAAATCAAATGGAAAGGGCCAAAAGTGAACAGGAGGGGGGGCAGGAGGGGGGACGG
+
0(0(8))))))28(.()2)3)((()25))()().)00('-3((-6(.(...))))))))).(,(((,,,,,,,,(((((+)&&))0)&)&(()&&&)&)05
@4DI
CAGCACGCCAGTGTCCCCACTGCATCATGCATCTCCAAACTCAACTCATACACCGAAACCTGACCGGGCCTTCCCAGCTCACCTCCCTCCATCGCAGTCC
+
C@CFFF8DHFHHGJJJJJIHIJIIJJJJJIGGGIIJIJJFGGIJJJJJIDHIICGGIGGJEHHHHFDDDDDDDDD@CBCDDABDDDBDDDDDDDDDDDDD
@4DJ
CTACAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTAT
+
@@@?DDDDFFFF?GE8<EFFF?F?GFFIE@DE>F<F??3?A'5.))6=C3=;?7.;;?DDB;@BBCC@B5;>3>A@>A5>(::A?@BBB>(((2<A<<3:@
@4DK
ACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCT
+
??@DDDDDDFBDH@F@EG9F<4:ABE;F*?EHHEGC>D:?:?BBHHIIGAH@GDAA;CFH)==CE@??CEECD@DDC;@C@CCCCCB@?C55>A5<?:ABC
@4DL
CCTCTCTCATCGGGAAGACCTGGCTTACATGAACCACATCATGGTCTCTGTCTCCCCGCCTGAAGAGCACGCCATGCCCATTGGGAGAATAGCAGACTGT
+
BCCFFFFFHHHHHJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHFFFFFEEDDDDDDDDDDDDDDDDDDDDDDDDDDDDDD
@4DM
TTCATTTATGTGTTATTGATGACTCCAATGAGCATATGCTTACTGTATGGGACTGGCAGAGGAAAGCAAAAGGAGCAGAAATAAAGACAACAAATGAAGTT
+
CCCFFFFFHHHHHIJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJIJJJJJJGHHHHFFFFFEEEEEEDDDDDDDDDDCD
@4DN
CACCGGCCTTCTCCTGACCCCGAGCAGCGGCCCCTCCGGTCCCCCCTGGACAACATGATCCGCCGCCTCTCCCCGGCTGAGAGAGCTCAGGGACCCAGGCC
+
:;+AB@DDDAHDHGGGHGIGHG><DFGE6:DAFHEB;@E'9?DBCB@BBBBCBAB93>C@>28?-0;-8@A>?BB9><@?BCCB?8@@CCA??@@?BA<8<
@4DO
GGGCGAGCTACTATAGAAAGGGAGGCTGTGCCATGCTGCCAGTTAAGTGGATGCCCCCAGAGGCCTTCATGGAAGGAATATTCACTTCTAAAACAGACAC
+
?;1BB@@D<A<A?FGEH<FHI=BCGDDBFB9?FGIE@??9BD/BFG@8=FH7CHG>E@EE=;;B=C>@CACA-;;=<?>>AC;@>C>>:@:>C@?<>@BC
@4DP
CTTCCCACCACAAGGCTTTAAGCAGGAGTACCACGACCCAGTGTATGAACACAACACCATGGTTGGCAGTGCGGCCAGCCAAAGCTTTCCCCCTCCTCTG
+
CCCFFFFFHHHHHIJJJJJJJJJJJIJJFGGIIJJJJJJJJCHHIJJJJIJIJJJJJJHHHHHFFFEEDEEDDDDDDDDDDDDDDDDDDDDDDDDDDDDD
@4DQ
TTTTTAAATGGCATTAGTTCTGTGTGCTATTGGTGTTTATTTGCATCCACCTGTCCAGTTGCTCTGCTGTCTTGTGTTTTTGCAGCCTCTACAACCCCACG
+
CCCFFFFFHHGHHIGIIIICHIGECGHHHIIII?B?FFHHIIGIIIIGCEHIIFHIIIIGGGIIIECHEDCFGG@A@DEEHEDFFF?CEEEEDDDDDDBDD
@4DR
AGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACT
+
@@CFFD<DF@FHCGGGGHHIGIJIIJJJIIJGIIJIHGIJJIIJJGIIIIJFHHHGFFCFFCDEDBBBBBDDDDDDDDDCDACDDDDDDDDDDBDBDDDDD
@4DS
AAGGATTTCCAGAGGGAGGCCGAGCTGCTCACCAACCTGCAGCATGAGCACATTGTCAAGTTCTATGGAGTGTGCGGCGATGGGGACCCCCTCATCATGGT
+
=@<A:BDDAF>FFIF@::@GB@@?DHHCFHFFHIIEICAFGBHIGBHICHG<DCAGAA)=EA?CECDD@A6;;>@B?BB>BBBBB<>BB<@<9@:A>AAA4
@4DT
TGGACCACAGATTTCGCCGCCAGCTTTCTGAACCCTGTAACTCCTTTCCTCCTTTGCCGACGATGCCAAGGGAAGGACGTCCTATGTACCAACGCCAGATG
+
?@@DDDDAHHHGHIIGHGGGGIGIHGHIGGIICHHII@B?FCGGICHGIGHGGGIIIGEF8>>@?BCC@B@BDBBB?BB<BB@CCC>::@CCDDDD@B<>A
@4DU
AGAAGCTGGGCCGCGTGGTGCACATCATCCAGTCACGGGAGCCCTCCCTGAAGAATTCCAACCCCGACGAGATTGAAATCGACTTT
+
;81:=AABF?FDFEG?C:?BDBE<BH@FBBFDHIIEIB/@85@E;???>DDC;A>>CACCCC?;',,;7;;&<A>>@CCC785?BC
@4DV
AATCAGATTCCTCTCCAGCACCGACTTTAAGAGGCGAGCCGGGGGGTCAGGGTCCCAGATGCACAGGAGGAGAAGCAGGAGCTGTCGGGAAGATCAGAAGC
+
@@@DDFDABHHGGIIIHIHGEFHIIIIIIEHAGGBGGIAAFHIGDD58ACDB3>ABCDB>C:@ACCDBDD?BB@C>>AA2?22>44?@B59<?>:>@@A?9
@4DW
TGAAAAGCCAAAATTTGTGCAGTGTTTAGCATTCTTGGGGAATGGAGATGTTCTTACTGGAGACTCAGGTGGAGTCATGCTTATATGGAGCAAAACTACTG
+
CCCFFFFFHHHHHJJJJGIJJJIJJJJJJJJJJJJJJJJJJJIJJJJJJJIIJJJIJIJJJJJJIJJJICGHHGEHFFFFFFECDDECCDCDDDDDDDDDD
@4DX
GCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGT
+
@@@DADDDBFDDFEGIIGHIEGHHGEAF>E:99DG9B:BFB<FDEFAHHI@BFEEDD@GHE7CGHCCCA;BB999=?;A:@A:::<29<<<(4:3:CCCC4
@4DY
AGCAGAACAAACCAAAGAAAAAGGAGAAAGACAAGAAGGAAAAGAAAAAAGAAAAGCACAAAAGGAAAGAGGAAGAGGAAGAGAATAAAAAAAGCAAAGCC
+
=:?DB3?D:?CFF=:A<<C?A<?<+:CGF9DD?FAD):8?BBB@;BBFF@8=@=D9A>>CBBDD1.6;=?=2??<(9<(599<<9>@BBBBBB-89AAB??
@4DZ
GGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCT
+
@CCFDFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJGHIJJJJJJIIJJJJJJJJJGGIJIJJIGIHHHHHFFFFEDEEEDDDCDDDDDDDDDCDDDDDDD
@4E0
TGAGGAACTCTCCAACTTTGCTTACCTCTTGGCCTCTAAACTTAGCCTCTCACCAAGGGAGCATCCCCTCAGTCCTCACCATGCCTCAGGAGGTCAGGGC
+
@C@FDDDEDFHHHJJGGHGHIGHHGIIEAHHGCFAGHGIIGGHI9BFDGEDHHHGEBBB=;8;=DHGE?=?EAD@C;@?CECCEDCCCCD@??5?@ACBD
@4E1
TCGATGGAGACATCAAACAAGAGCCAGGAATGTATCGGGAAGGACCCACATACCAACGGCGAGGATCACTTCAGCTCTGGCAGTTTTTGGTAGCTCTTCTG
+
@@@DADA>AAAD<F@FAHEI@ACAFCEGCAGA?D9D=<6G>FIIIBHIIIEHGB>7CDHD@?:@?CCB>3@@(4AA>ACC:9?<ACCB<@@CA>:@@@@CC
@4E2
GAATTTTTGGGAAATATGAAAAGCCAAAATTTGTGCAGTGTTTAGCATTCTTGGGGAATGGAGATGTTCTTACTGGAGACTCAGGTGGAGTCATGCTTAT
+
@@@FFFFFHHHFHIHGHIGGIIGIIGJJIIJIJDGHIJFFFFHIJIJJJEGIIJHGEIJIJJJIJJJJJHHDHHFEFDCBCEEECCAB@?CCDCDDDDDD
@4E3
CCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATGACATCTCCTGTGACTCTCACCTCTCAGACAACTAAGACAGATGACCCCCAATTGAAAAGAGAAAT
+
@@@FDBDDABDFDGCIIDDEFEGGEBDHCEGE=E@@GGEG@HIGGHIIGGDH@D>FGGBHIIIIGGHGHIIA;@DH??A>B7@BBCBCC@CCCDC?CCAAC
@4E4
CTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCC
+
CCCFFFFFGHHHHJJIIIIIIJJIJJJJJJGJJJJGGIGIJJJJJJJIJJJIFIIIIJHHGHGFCEEFFEEEEEDDDDDDDDDDDDDDBDDBACCCCDD
@4E5
TTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGC
+
@C@FFFFFHHHGHGHIJJJJIJJJIJIJIIIIJJJJIJIJJJJGJJIIJJJJJJIJJIJIIIIHHHEHFEFFFFEEEEDEDDDACDDDDDDDDDDDDDDDD
@4E6
GTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGC
+
@@@FFFFFHHHHHIJIJJIIIJJGJGHIJJJIIJIIJJJIIJJJJJJIJIHIHFHHHFEFFFFEDEDCECDDDDDDDD@ACDDDDDDBDDDDDDDDDDD
@4E7
CACCGCAGTGCATCAGAACCCTCCTTGAATCGGGCTGGTTTCCAAACAGAGGATTTTAGTCTATATGCTTGTGCTTCTCCAAAAACACCCATCCAGGCAGG
+
CCCFFFFFHFHHHJJJIJJJJJJJJJJJJJJIIJJJJJHIIJJJJJIJJJJJIJJJJHHHHGHHFFFFFFFAEEEECCCDDDDDDDDDDDDDDDDDDDDDD
@4E8
AGAACAGATTGTGCAAAAGAACCAAGAAATAAAAAACATGAAATTAGAGCTGACTAATTCTAAGCAAAAAGAAAGACAGTCTTCTGAAGAAATAAAACAGT
+
@C@FFFFFDHHDHIIGHGJIHIIGIIEHHIJJJJJJJJJJIIJJJIJJJIIIIJIIIIIIGJJJJJJJGHHFFFDDEEEACEECDCEDDDDDCDDDDCDD>
@4E9
TAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACT
+
CCCFFFFFHHHHHJJJJJJIHHIIJJJJGIGIJJJJJJJJJJJIJJJJJJJJJIJJIJJIJJJJJJJHHHHFFFFFEEDEEDDEEDDDDDDDDDDDDDDD
@4EA
CTTCATCCTCAGAAGACAGGAATCGAATGAAAACACTTGGTAGACGGGACTCGAGTGATGATTGGGAGATTCCTGATGGGCAGATTACAGTGGGACAA
+
CCCFFFFFHHHHGJIFGIGGIJJJJIIIIEHIJJJJJJIIGGIIIIJJEEDHGCGA@;EHHGIJHHHEBCEDDCEEEDEDDCBDDDCCCDCCDDBDDD
@4EB
CTTTCCTGTATATTAAACCACGTTTTTGGCTTTTTCCTTCCTGTCCTTCCCCATCTGGCGATGGTGAGGATGGGTTTTTTCTCTTCCATGTTATCATCAGG
+
@@?A?DDFFHFHFDCECEHGIIHEGGDHGEGIIIGIGEIIIIIIIIIIIIIIIEGGBHEEEBHBAC7?D@>BBB6=BBBBCCCCC@@3>A:@B>+:>CCCA
@4EC
CACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGAT
+
CCCFFFFFHHHHHIJJJJIJJJJJJJJJJJJJJJJJFHHGIJJIJBGIJJJJIIIIIJJJJIHHGHFFFFEDDEDDCDBCDDEEDDDDDDDDDDDBDDDDC
@4ED
TGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTC
+
<@<DFFFFHFHHHIIIIIEGGGBFHII>EE?FEGIIIIIGIIII>DFGGHFIIGIGIIICHIIHHFFDDECB>ACACDDBDDBDADACCDDDDDCDDDDDD
@4EE
GGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTAC
+
@@CFFDDFGGHHHJIJIIHIJJJJIJJJJJJJJJIJJJJJJJJJJIJJIIIJJJJHHHHFFFFFDD3>ACDDDDDDDCCDDDDCDDEEDDDDDDDDDDDDD
@4EF
AGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAACCAGCTATGGGCAGCAGCCTCCCACT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJIJJJJJIJJJJJJJJJJJJJJJJJJIJHIIJJJJHHCHHHFFFFDDDDDDDDDDDDDDDDDDDDDDDDBD
@4EG
AAAAAAGAAAAGCACAAAAGGAAAGAGGAAGTGGAAGAGAATAAAAAAAGCAAAGCCAAGGAACCTCCTCCTAAAAAGACGAAGAAAA
+
CCCFFFFFHHHHHJJJJIJJIJIJJJJJGIJFGHIJIJJIJJJJJJJJJIHHHHHFFFFDDEEDDDDDDDDDDDDDDDDDDDDDDDDD
@4EH
AAAACAGTGAAAACTTTATAGTAGTGGTTGATTCCAACTTGGTTGAAAAGATCTGTGCAGAAGAGGGGAAATAGAGTGACATGAGGGGTGGGAATTAAA
+
+1+<7=+,2+2<7+++,,3,3,,,,37+22++***1***1*1*:)****00*0**00*0*)).)(.-'''()))..7;).).((.((''''&+((++((
@4EI
ACTGGCTATTGTTACCCAGTGGTGTGAGGGCTCCAGCTTGTATCACCATCTCCATATCATTGAGACCAAATTTGAGATGATCAAACTTATAGATATTGCAC
+
@@@D?DEDFHHFFDEHG>GFEHACFHGHGGGIIIIGIIGGBFEBFHIIII@EHEBHCHEGIIIIIIGGDGIHHHEHDFFFFFCCA@>AC>C>C@C;>ACC@
@4EJ
GTGTTAGACAGAATGGCTGAATCACAAGAAGCTGAATTAGAGAGGCTGAGAACACAGCTTCTATTTAGTCACGAAGAAGAGCTTTCCAAACTGAAGGA
+
@@@FFFFFHHHGHJIGJJJJJJJJJIIJIIIGIJJIIJJJJIJJIJJJJCHIGGIJIJJJJJGHIJGHIJIIHHFFFFEEEEEDCCDEDDDDDDDCDD
@4EK
CAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCT
+
@@@DFEFDHDHDFIGIIGDGGHIJJCGHIIJIJJJJIHIIIGIIJJJIIHHHFHFFDEFFEEEEEDDDDDBDDDDDDDDDDD?BBDDDCCDDDCDDDDBC
@4EL
GCCTGTCAGCTCTTGAGTCACGAGTTCAGCAACAAGAAGATGAAATCACTGTGCTAAAGGCGGCTTTGGCTGATGTTTTGAGGCGTCTTGCAATCTCTGA
+
@@@DFFFFHHGHHFIIIGHHIJJJHGJIIJIJJJJIJJJJGJJJJJJJIJJJIJJJIIIJIIJFFDEEECDDBDCDDEDB?BDBD<BBDCACCCCDDDDC
@4EM
CCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCGGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCT
+
@@@DADBDHDF8CCBDHBGEBGEECBHHCBF?GHEGGCHI?HGHBDHHHEHCD@CHGHGI'@=EEEEBD@ACCC>CACACBCCCACBBCB@B<BBBB<?C
@4EN
GCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGC
+
@@CFDDFFHHFHHJGGIBHJGCGGDFFEGGGIEHGIJGG;?GGGGCHHHIJGEHIGI@FHIIIEGGHHEHHEHE?CEEEAEDECEDCDDDDCCDDDD?BD
@4EO
GTGGCAGTGAAAATGTTGAATGTGACAGCACCTACACCTCAGCAGTTACAAGCCTTCAAAAATGAAGTAGGAGTACTCAGGAAAACACGACATGTGAATAT
+
@@@ADDD=ACFFDHGIIGHIGIC?AFHCG+ACGFH>FGHIGAGGHD?GHD9FAFHEFFHGGEHGGGH)=@@@CE7AHE=?B;@@C3.=@BBBBC@@@>BAA
@4EP
CATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATAT
+
@@<BDDDDDFHHFEFCEHHIIB@8CGFFHGG;DB?FDHIIICHCGHGEHGHHGGDEFHGIDHGGGAEEEA?EEABABCBBC>@@CC@@CCCC:@>>>A@CC
@4EQ
CAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGC
+
@@@DD?D?CFFHHHHGIIIEHIIFGGGHG>?DCGGIGHIIICHHBGI@FGCHGEIGICHIIGHHFHHHDBBDCECCECCCCDCCCCCCCACCCCCCCDCB
@4ER
CAACAAGCTCCCCGGCGAGAAGCTGGGCCGCGTGGTGCACATCATCCAGTCACGGGAGCCCTCCCTGAAGAATTCCAACCCCGACGAGATTGAAATCGACT
+
CCCFFFFFHHHHHJGIJJJJJJJJJJJJJJJJEFFBDEEEEDDDDDDDDCDDDDDDDDDDDDDDDDDDDDDDDDDDEDDDDDDBBDDDDDDDDDDDDDDDD
@4ES
CTTCCACGGCATTGCCCAGGCTCTGCAGCCACATCCGACCGAGTCGTCCATGTACAAGTACCCTTCTGACATCTCCTACATGCCTTCCTACCATGCCCACC
+
CCCFFFFFHGGHGHGJJJJGGJJJJJIJJJGIIIIJJJJJJJGGGHHFHFFFFFFFEECEEEDDDDDDADDDDCDDDCDCCCDDDDDDDDDDCDDDDDDDB
@4ET
GGCTTCCTGGCTCATCCCAGCAGAACAGAAGGCTGTATGTTTGAAAAGGGCCCCAGGCAGTTTTATGATGACACCTGTGTTGTCCCAGAAAAATTCGATGG
+
@@@B=ADEDHHHHIIEGDCHGHIGECFHIFGIFIG1???:BFBDHHGCCGGCGG;@@CEC@@G@>EAEEHFE;@=;;@A6>B=;@CCCBCCC<AA>?:CCB
@4EU
CTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGC
+
CCCFFFFFHHHHHJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJIJJJJJJJJIJJJIJIIJJJJJJJJJHHHHHFFFFFDEEDDDDDDDDDDDDDDDDDD
@4EV
GCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCC
+
CCCFFFEFHHHHHJJHIJJJJJJJJJJJJJJJJJJJJIJIJJIJJJJJJJJIJJJJJJJJJJJJHHHHHFFFFFEEEDEDDDDDDDDDDDDDDDEEDEDDD
@4EW
TGTAAGAGCACCCTGCCGTGCTAGAGCTGCAAAAAGAGGGCAGTCCACACCCCCTACCACCACAATGGCAGTTAGAACCATGGGGGGCCCGGAGCCAACC
+
(0--(@)2))(2<8:(632(((2)))..@<<>37<5536/9<=)..>>???'5''-..;=,(6(68((((,(-7,550((,3,(())0-&&)&&&(+3(&
@4EX
CAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGC
+
CCCFFFFFHHHHHJJJJJIGIJJJJJJJJJFHIJJJJJJJJJJJJJJJJJJJJIJJIJJJJJJJJHHHFFFFDEEDEDDDDEDDDDDDDDDDDDDDDEDD
@4EY
GGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTC
+
??<BDDD:DDCCDEDEEB@<:CDFEEFAADD?DDIDEDDBDDDE@9<BCDAC@CD>@7@CDA;CA?)=CDD>@DA>@@A??5>>>A????;5<88<?4::
@4EZ
CAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATAT
+
C@CFFFFFFFHHHEGIIDHIJGJJJJJJJJJJJJJJJIJJFGIJGGGGGHGHGHIIJJJJJJJJHGHGFFFDEFEEEEEDDDDDDDDDDDDDCDEDEED
@4F0
GGAACCTCCTCCTAAAAAGACGAAGAAAAATAATAGCAGCAACAGCAATGTGAGCAAGAAGGAGCCAGCGCCCATGAAGAGCAAGCCCCCTCCCACGTATG
+
CCCFFFFFHHHHHJJJJJJJJJIJJJJJJJJJJJJIIJJJIJJJJJJJJJBGHIIJJJJJJIHGHHFFFDDDDDDDDDDDDDDDDDDDDDDDDDDDD?CDD
@4F1
AGATCAGATAAAGCTAATGAATGTGGCAATAAATGAACTGAATATAAAATTGCAAGATACTAACTCTCAAAAGGAAAAACTCAAGGAAGAACTAGGACTA
+
1;?DDDD?DAD>D+<CE2<<?@A<CEEFDEF<FEFEFAEA3C@D9D<?<90:<D9??@?BDD>*B8@==CCEEDIIEIIACA;;>7??@AA>6AA>A>;>
@4F2
GTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTAC
+
@@@DDFFFFDBHHHHIJIGGEGHEDEGGGIGJGGIDIDHIFIG@HGIJIIII>FHHGIJCHCAEEAEHF>BD>@CCCEDDBDDBDBBDCCBDDBBCC:ADC
@4F3
AAAAGTTCTGTCTTTGATGAAGACAAAACTTTTGTAGCAGAAACATTGGAAATGGGTGAGGTTGTTGAAAAGGATACAACAGAACTCATGGAAAAACTTG
+
CCCFFFFFHHHHHJJJIJJIJJIJJJJJJJJJJIFIJJJJJJIJJJJJIGIIJJJJFHGHJFHIJJJJJJJJJHDHGHFFFFFEEEDDEDDDDDDDDDDD
@4F4
CTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTAC
+
CCCFFFFFHHHHHJJJJJJJJJIJIJJJJJJJJJJJJJJJJJJIJJJJJIJJHHHHHHFFFFFFDEECEDDEDDDDEDDEDDDDDDD@CDDDDDDDDDDDD
@4F5
CAGTAAGGTACGGAGTAACTGTCCAAAAGCCATGAAGAGATTAATGGCAGAGTGCCTCAAAAAGAAAAGAGATGAGAGACCACTCTTTCCCCAAATTCTCG
+
CCCFFFFFFHHHHIJFHIJJJIJJJJJJJJJJJJJJJJJJIJJJHIJJJJIJFHIJIIJJJJJJJJJHHHHFFFFFFEDEDDDDDDDDDDDDDDDDDDEDB
@4F6
GATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCC
+
@@@FFFFFHFFDFGHEIJJEFHIIHGIGGIJJJHHJGJIEBFHHIIJIII;EGHCEEEDBB?A??@?CACD@CACCCDAC@DCCA@@@ACCDCCDC@CCB
@4F7
AACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACC
+
CCCFFFFFHFHHGGIIJIJIBHIJIIGIJIIIIIHBGDHHGEIJAGHIIIIJIHCHHFFFFEEDDCDCDDDDDDDDDACACDDCDDBCDDDDDDCBDCDDD
@4F8
TATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTT
+
CCCFFFFFHGHHHJJJJJIIJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJIJIIJJJJJIHHFFDEEEEEDDDDDDDDDDDDC8ADCDDDDDDDDCC
@4F9
TAACAACTGCTGATAAATTACTAGGAGAATTACAAGAACAGATTGTGCAAAAGAACCAAGAAATAAAAAACATGAAATTAGAGCTGACTAATTCTAAGCA
+
@@@FFEDFHFHHHIIGGJIGIGHHIIGEEGIEHICDHIJHJJJJJBHIJIHH@DGGGIAHCHGGEHJJJGHHBDFFCEEEECEEDDDDDDDCDCDDACCC
@4FA
TGATGATTGGGAGATTCCTGATGGGCAGATTACAGTGGGACAAGGAATTGGATCTGGATCATTTGGAACAGTCTACAAGGGAAAGTGGCATGGTGATGTGG
+
CCCFFFFFHHHHHIJJJJJJJJJJJJJJIJJJJJJGHJJIJJJ)BGHIJJJIJJJJJIJJJJJJJJJIJJHHGHHHFFFFDDEDE;@CDDDDD5>ACDBCD
@4FB
GCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATG
+
@<@DFDDDBCDHFB<ACDGA@FCDHBDBHIBC<?FA??BFGHEFBBB9DGIBDAHF;@@@CHHEE@>B@;;>;>;55>>CCCCCCC@AACBC9?C<?C44@
@4FC
GGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATC
+
BBCFBDEDHGHHHJJFHIJJJJJJJJIJJJJJJIIJJJJJJIIJJJJJJJIJJJJJIJIJJJJJJIHHHGHHFFFEFFEEDEEEDDDDDDACDDDDDDDDD
@4FD
GAAAAGTTCTGTCTTTGATGAAGACAAAACTTTTGTAGCAGAAACATTGGAAATGGGTGAGGTTGTTGAAAAGGATACAACAGAACTCATGGAAAAACTTG
+
@@@ADBFEHDFFFHGHIGJJJJJGIGIGJJJJJIJFIIGIIJJIDGIIHGCIGHHIIFGIJBBFHIJIIIJGIGFEHHFFEDEEECAEDCCDDDDDDDDDD
@4FE
TATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGG
+
1=;<+<=A=A=<A;2<<87<)11@?A=>BB>BBBB7?B>B>=A05=6=A;;=A>>@>>>>;@B@;;;;;==99=::;921;(83338(88(29;88?????
@4FF
CCCTCTCTCAGCCCCAGCAGAACAAACCNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNAAGAGGAAGTNGAAGAGAAT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJI#####################################################++8?BDDDD>#+8??@BCDC
@4FG
CGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGG
+
??@DBDDDHBFDFGHHB@FEGG<FHGGIGIIGIHIGIIGIIHIDB?>DBDHGB@FGGHGGCG@?EEEEFFFFD;@CC@CCDDDCACCCAACCCC<?AACDA
@4FH
TGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTAC
+
=@<D?DDDHDDHFIIIIGHIIIFGGGGGHE??FHHEGIGDGGGGHIICCH@BH@@GCAGG@CA?CEBFFA@>@CCCCCC@>@BBCBBBBACCCCACCCCC
@4FI
CAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGC
+
CCBFFFFFHHHHHJJJJJJJJJJJJJJHHJJJJJJIJJFHIJJJJJJJJJJJJJJJJJIJJJJJJJHHHHHFFFFDDDDDDCDDDDDDDEDDDDDDDDDDD
@4FJ
CATCAACCAAGAAGGAGAATATATTAAAATGTTTATGCGCGGTCGGCCAATTACCATGTTCATTCCTTCCGATGTTGACAACTATGATGACATCAGAACGG
+
CCCFFFFFHGHHHIIIJJJJJJJIIIJJJJIEGIIGIJJIJJHHIJJIIJHHGGHHHFFFFFFFEEEEEEDBDDDDCDDDDBDDCDDDDEDDDDDDDDDDD
@4FK
CACACCATGCTCCCCATTCGCTGGATGCCTCCTGAAAGCATCATGTACCGGAAGTTCACTACAGAGAGTGATGTATGGAGCTTCGGGGTGATCCTCTGGG
+
CCCFFFFFHGFGHJGGHIIJJIJIGGJIGGHIJJJJIJJJJJJJJDEHIGGHGIIJIGIIGGEEEHHF;B?CECEEEC@CDBCDDDDD8<?CDDDBCCCD
@4FL
CTGGAGACTCAGGTGGAGTCATGCTTATATGGAGCAAAACTACTGTAGAGCCCACACCTGGGAAAGGACCTAAAGGTGTATATCAAATCAGCAAACAAATC
+
@@@DDDDDHFHFH<FHHGBFGFHGIIGIGIGHCFIGIIEGEIDHIGHGIGIIEGIGDEAGIIGIGIGHHHFEECEE7>;AD;C;@CAC@CACCCCABBBAC
@4FM
CAATCAGGAGGTCGTACAAACTGCATCAGGAGATATGCAAACATATCAGATCCGAACTACACCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATGACAT
+
<?<?B>BB+<?2<@FFFBFFGII@<?CEB??@?9DDG<FGIBG<B?8?DF??CF7(;FCAE;DA=AAEA@>?;>?;>BC;6;;=BB95@,55,5@::@4>:
@4FN
ATTGCCGGCTCCTCCAAGATGAAGGGCTTCTCGTCCTCAGAGTCGGAGAGCTCCAGTGAGTCCAGCTCCTCTGACAGCGAAGACTCCGAAACAGGTCCTGC
+
@@@BD??@DHFDDBHIGBGEGGDB>FF??BGGHIIGGGIDGGBGGB6EEHHEHFFF?BBB@CCCEACACCCCCCACC5;@BB<CCCCBBBBBA<ACCCCCC
@4FO
GTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACA
+
@@@DDDDFHFHHHJGHGIIIGIIJIGGGIGGIIIHHIIJJJGIJGGHIHIJGJEGHIJJJIJIGIJIHFEHHEEFFEEEDDB?CADDDDCCCCDDDDDD
@4FP
CCACACCTGGGAAAGGACCTAAAGGTGTATATCAAATCAGCAAACAAATCAAAGCTCATGATGGCAGTGTGTTCACACTTTGTCAGATGAGAAATGGGATG
+
@?@DD?DDDDHGHGEEH@GH?EEECFDCFCEBEDHCE9CFHIIHGHIGBDACEFHIIEHIIBHGGII7@=?AEA?A>?B@DEEECE>;>>@CCDDDCA<>@
@4FQ
ATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCT
+
CCCFFFFFHHHHHJJJJJJHIJJJJJJJJJJJJJJJJJJJJJJJIIJJJJJJIJJJHHHHFFFFFEDD>@DDDDDDDDD:ACDDDDDDEEDDDDDDDDDDD
@4FR
CTCTGTTCGAGTCCCTAGAGGGCCGGCCGTGGAAGGGGGACACGTGAATATGGCATTCTCTCAGTCCAACCCTCCTTCGGAGTTGCACAAGGTCCACGGAT
+
CCCFFDDEHHHFHJJJJJJJJJJJJIIJJHJJJJIJJJJGFFFD>BDDDEEEDDDDDDEDDDDDACDDDDDDBDDDDDDDBD@CCDCDDDDD@CDDDDDD>
@4FS
CTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJIJIJHHHFFDDDDDDDDDDDDDDDDDDDACDDDEDDDCD
@4FT
AAAATGTTTATGCGCGGTCGGCCAATTACCATGTTCATTCCTTCCGATGTTGACAACTATGATGACATCAGAACGGAACTGCCTCCTGAGAAGCTCAAACT
+
CCCFFFFFHFHHFJJJIHHIIIJJJJJJJJJJJIJJJJIJJJJJJIJJJHIEEHHHHFFFFEFFEECEEEDDDDDDDDBCCDDDDDDDDCCDDACDDDDDD
@4FU
CGCCTAGAGGGAAAGCGAGAGGGAGACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGC
+
@@@DDD;;DFADBFBB@E?F@EEGD@=@<<GIAFE;FHGGGEGBE<5?B;ACBBBB@@CCC>:5??58>BC7>@>BCCCCE@ACAA>CDCC@AB<@CC>C:
@4FV
AAAATGACGGGTGGGAAGAGGTTAGTTGTCGAAGGGCACAGGGAGGGAGAAGGGGGGGGAGCGGCCCTAAAAGGGGCTACTGCGAAGGTTACCGCGGGT
+
(-0@3.9):((0(2(()(1(()()())1):=((-(((--6).((''-','().,,'&)&&05-&)&&+((+(((+0&&(+(+400&))++(82&&&)&&
@4FW
TGGCGCCTTTGGGGAGGTGTATGAAGGCCAGGTGTCCGGAATGCCCAACGACCCAAGCCCCCTGCAAGTGGCTGTGAAGACGCTGCCTGAAGTGTGCTCTG
+
???DD68AD>DD?:2@@1:?EEACB@DD@DDD?BBDE?D6@BCEACAADDDDDDD==@@>??8895:A>AA???13:A:>>05>9??AA<>A44:344:>>
@4FX
GGGCCACATGGGACAACCGGGGAAGGAGGTCCTGTGGCCACTCTATCCAAGCCTTCCCTAGGTGACCGCTCCAAAATTTCCAAGGACGTTTATGAGAACTT
+
@@CFFFFFHHHHHJJJJJJJJJIJJJJJJHJJJJGIJJJJJJJJJJJJHHHHFFFFFEEEEE>CCDDDDDDDDDDDDDDDEEDDDDDDDDDDDDDDDDDDD
@4FY
GTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCC
+
@@@DDFFFHHGGFIJJIIIIIIJEGIJIGGJIJGIE>GEHIIIGIIIIJJJJJJGIGGGHEFHHHFCCBDCECDD?BBDD>@CCDDDCC@CDDDDDDDDDD
@4FZ
CGCCTGTCAGCTCTTGAGTCACGAGTTCAGCAACAAGAAGATGAAATCACTGTGCTAAAGGCGGCTTTGGCTGATGTTTTGAGGCGTCTTGCAATCTCTG
+
@CCADDDDDDHHDGIGIGIDFHGIIIIIIGGE>@GEHGIIIIIIIIGGIHIFGIEHGIICFGGHBBDEECCCDBDDEDDDBD@?<@>BBDA@@@ACDCED
@4G0
GTTCACTCCGCTATTACTATGAGAAAGGAATTATGCAAAAGGTGGCTGGAGAGAGATATGTCTACAAGTTTGTGTGTGATCCAGAAGCCCTTTTCTCCATG
+
CCCFFFFFHHHHHJIJIIJJJJJJIJJIJJJGIIGIJJIJIIBFHIJIIJIIGIJIJIJJIHIIJJJH?AHH>C;BDCCEDEEEDDDDDDDDDDDDDDDDC
@4G1
CTCTTTCATCTGCTGCTAAAAGTGGTACAGAAAAAAAGAAAGAAAAACCACAAGGACAGAGAGAAAAAAAAGAGGAATCTCATTCTAATGATCAAAGTCC
+
@@@FDFFFHHHF<?FGBGGGGE3CE<A<HHHIIGCDGGIDGDDHIIHIIIIIIIIHHIGFEA=BFDB@@BBC<528?@:@@CCDEECDDCCACCC>A>>3
@4G2
TATATTAATATGTTTATGCGCGGTCGGCCAATTACCATGTTCATTCCTTCCGATGTTGACAACTATGATGACATCAGAAGGGAACTGCCTCCTGAGAAGCT
+
--02>4)@)).6848.).2(-@((:(3(3=19><=3)6)=1=)).<=;>:6-'6=:8>?@=;.67.==(==8;1;7;<=(5,,8;60,+2+(22:((+(8(
@4G3
CAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTTATGGGCAGG
+
?@@DB?BD?CBFDFEGEBFIBHIIIEGE;FHCFHHEEGFHIGE@@@AFGFDGGE=@@EHI@@D:AB9;>;=A==BBBB5ACCCCC?A(00??>CCCB8?@9
@4G4
CCTGAAGGTGTACCCGCCACTGAAGGGGAGCTTCCCGGAGAACCTGAGACACCTTAAGAACACCATGGAGACCATAGACTGGAAGGTCTTTGAGAGCTGG
+
@@@DDADFACFFHEHGEFGGIIGHIGH:?@GIGGHGGIGEHH@FGIJEHFHFHFFDDCEEEEEDDACCC?>@BACDC>@CAACCAB3>>@CCD8?ABDCC
@4G5
GTAAAAATAAACAGGAATTAGAGTATAAAAGTAAACTTAAAGCACTTAATGAAGAGCTTCATTTGCAAAGAATAAATCCAACTACAGTGAAAATGAAAAGT
+
@BBFFFFFHHHHHJJIJJJJJIJHIJJJJJJHIJJJJJJJJJJJJJJJJJIJJGIIJJJJJJIJJIJJIIIJJJJJIJIJHGHHHFFDDFFEEEEEEDDDD
@4G6
TGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTC
+
?@@DDBDFHFF?FFHIGIIIIGGEFHIHIIIIHIIIIIIIEEHEHIGIDHIGIIIGIHIIIIIIIIIIHEHHD<ACBCCDDDCDDCDCCDDDCCDDDCDDD
@4G7
AGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAAC
+
@C@FFDDFGDFHHJIIJEFIH@HIIGIJIGHGGHGGGGHGG@GHEHJIGGGGGGHGGHEHGGGJJHFAEEHFDDFFECCE@EECACCCCDBDCCCD@BDDB
@4G8
ATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCA
+
?B@FDFFFGHHGFGJJIJJIJJJJIJIJJJIIJJJIGGGGIJJJJJIJJJJIIJJJJGGHCGIIJHHFBEDDEDDDDDDDDDDDDDDDACDDDECCD@CD
@4G9
ATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTT
+
CCCFFFFFGHHHHJIJIJJJJJJJIJJJJJJJJJJJJIJJJJDIHIJJIJJJJIJJJIJJIJJJIIJHHHGFFFFFFECEEDDDBDDDDDDDDDDDDDDDD
@4GA
GAAAATGAGGACCTCAAACAACAATGTATTCAGCTAAATGAAGAGATTGAAAAGCAAAGGAACACTTTTTCATTTGCTGAAAAAAACTTTGAAGTTAACT
+
=<=D+==:=D<DHEH@CEIE???FHA2<<A:1:CGI>9:?1:0:8):99DDB??8BD;888C=688==E;.==7C>=??C;@?DC?B@CA>>>@;A@A:5
@4GB
GGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGC
+
@@@DFFFFHHHHDHJJJJIJIJJIIJJJJJJJIIJIIGHIIGIJJJJJJJJJJJGGDDGHJJFHHGHFFFFCEEEED>CDDDDDECDDDDDDDCDDDDC
@4GC
GCATTCTTGGGGAATGGAGATGTTCTTACTGGAGACTCAGGTGGAGTCATGCTTATATGGAGCAAAACTACTGTAGAGCCCACACCTGGGAAAGGACCTA
+
?@@+BDFDHGFFHIBHIJIIGHIJJJJJJII>FFGGIIJIJBGHEDGHGFEGIIJIIIIGGGHGGGIIIJHHFHECHEFFEDCDBDDDDDDDDDDDADDD
@4GD
CCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTTATGGG
+
@@@;DD3BFFDFF+CFEFIHDHFFD4C4EF9EDGDDA9D9DG8DBFD6:6<F/;==EE=@EEEFDEC??C???@B?@BBBBBBBA4>ABB?(058<>>4:8
@4GE
GATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGC
+
@;@DDBDDFFHFD@ABHHC@CHHEHEGGHEAFBBGB??FHCGI>G>F>FHGIEGIIIGDCFHCHGIIGEEFFEEDECDCCCCCBCCCC@;<CBBABB?B??
@4GF
CCATTCTATACCAACACCTATTCTGATTTTTCGGTCACCCTGAAGTTTATATTCTTATCCTACCAGGCTTCGGAATAATCTCCCATATTGTAACTTACTAC
+
1?@DD;DDFA?DFBGIGIIDGIGFH@HHHGI?EGG:FDC@?GDHEHHIEIIHH8EHGI4BFHFHIIIEHG@BE7?;B@A@C;C;?CCDEE>@C;>AA:>>A
@4GG
CAATTATATTATCACCTACAACATAGCCTCCATGAATATCATTAACCTGTTCTTATACCTTATCCTAATTAACTTGACTAGAAGCACACAAACCCCC
+
-(-(())28.6)>).2)29)))(3=1>8)=(=)).).)))))293).0()).).0<<1=3).)<>;=9.)8)))))/.))).=).8).((,(.(,9;
@4GH
AACAAGCCCACCAGCTTGTGGAACCCAACGTACGGCTCCTGGTTTACAGAGAAACCCACCAAAAAGAATAATCCTATAGCAAAGAAGGAGCCACACGAC
+
CCCFFFFFHHHHHJJJJJIJIJJJJJJJJJHIIHJIJIJIJJGHIJJJJJIJJJJHHHFFFFDDDDDDDDDEDDDDDDEDDDDDDDDDDDDDDDBBDBD
@4GI
CCCACATACCAACGGCGAGGATCACTTCAGCTCTGGCAGTTTTTTGGTAGCTCTTCTGGATGACCCTTCAAATTCTCATTTTATTGCCTGGACTGGTCG
+
@@@FDFFFFDHHGJJJJJJIIIIIIIJAFHIIDHCGIGGIIJI@EABDCCCCAEE;A@CCDDDDDDDCCCDDDDCCC@CDEEEDD@>ADDD??CAB>A<
@4GJ
CATGGAACGTCACATCAACGAGGAGGACACAGTGCCTCTTTCTCACTTTGATGAGAGCATGGCCTACATGCCGGAAGGGGGCTGCTGCAACCCCCACCCCT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJIJJJJJJJJJJJJJJJJJHHHHHFFFFFDDDDDDDDDDBDDDCDDDDDDDDDDDDD
@4GK
GGAAGATGCAGAGGCGCCTCCAAGTTTCAGTGGCGCTCAGTTGGACTCAAGTCCTTCTGGTTCTGTTGAGGATGAAGATGGGGATGGGCGGCTTCGGCCCT
+
CCCFFFFFHHFHFIJIIIIJJJIIIIIJJJHIJJIJJJJJHJJJJJJJJIIHIGJHHHHHHFFFFDEEEEEACCCCCCCCDDD@BDDDDBDDDDCDDBBDB
@4GL
CAGACTGTGTGAAATGCCTTGCTATACATCCTGACAAAATTAGGATTGCAACTGGACAGATAGCTGGCGTGGATAAAGATGGAAGGCCTCTACAACCCCAC
+
BCCDDDFDFHHFHJFIIJJJGDHJIIIIJIIIJJIIIJIIJJIJJFHGIIIIJJFICEHIHJJJGGEIH;AEAHFFD@BEECACEDDDABDC@AA@BBDDB
@4GM
GTTGAAAAGGATACAACAGAACTCATGGAAAAACTTGAGGTAACCAAGCGAGAGAAATTAGAGCTGTCACAGAGACTGTCTGATCTTTCTGAACAATTGA
+
C@BFFFFFHHHGHJJJJJJJJJJJJJJJJJJJJJJJJJJJHHIJJJJJJJJJJJJJJJJJJJJJJHHHHHHFFFFFEEEEEEDDDEDDDDDEDDDDDDDD
@4GN
GCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACT
+
@@@FBDFDFFHHGJIGIEFHEHIJJIGIIIJIJJJJJJJIGHGIJJJIJIJIIJJJCHICGICGAHFHDFFEEDEEECDDDD?CDD@CCDDDDD@DCBCCC
@4GO
TGCATTTGGAATTGTTCTGTATGAATTGATGACTGGACAGTTACCTTATTCAAACATCAACAACAGGGACCAGATAATTTTTATGGTGGGACGAGGATACC
+
CCCFFFFFHHHHHJHIJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJIJJJJJJIJJJJJJJJJJIJJJJJJHHHHHHHFFFFCEDDBDDBDBBCDDD
@4GP
CGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTAT
+
CCCFFFFFHHHGHJJJJJJIJJIJJJIJIJJGIJJJJJJJJJIHJIIIIIIJJJJHFFFFFFDDDDDDDDDDDDCDDDCDDDDDDBDD:ACDDDCDDEDDC
@4GQ
CTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJIJJJJJJJJJJJJHHHHHHFFFFDEDDDDDDDDDDDDDDDDDDDDDC
@4GR
CCTGGTTTACAGAGAAACCCACCAAAAAGAATAATCCTATAGCAAAGAAGGAGCCACACGACAGGGGTAACCTGGGGCTGGAGGGAAGCTGTACTGTCCC
+
@@@DBADDHHHHFG@HGGGGIIIIIIIGIGGGGIIIIEGDHGEGGIIIICGGGGFC;CHIIHHEED>3=C@@C=ABBBBB:ABBBBBBBCC:ACDCECCC
@4GS
CTCCTGTTTGCGGAAGAAAAGGAAACCTCAAGCTGAGAAAGTTGATGTGATTGCCGGCTCCTCCAAGATGAAGGGCTTCTCGTCCTCAGAGTCGGAGAGCT
+
B@BFFFFFHHHGHGIJIJJJJIJJIJJJIIIJIJJJJIIGIGIJIJICHGEIBDHIIJHHFFFFFEEEEEBCDDDDDDDDCDDDDDDDDCC:A>BBBBDBD
@4GT
GGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGC
+
CCCFFFFFFHHHHJJJJJIIJGGIIJIJJJIIIJIIJJIJJJJJJHIJJJJGIJJIJHHDFFDDDDBCDDDDDDDDDDDCDCDDBCBDDDDB@BDCDEDBD
@4GU
CAGTAAGAATACGGAGCAACGGCCCCAGCCAGATCCGGATCAGATCCTGGGCCCGACCAGCAGTCGCCTAGCCAACCCTGGAAGCGGGCAGATCCAGCTTT
+
-(-==>??>?=)(83=3@).=:>-=4(3(((00:7=('7-'7)==?;)<0(.:35=59'(8(5;(89(&)8:66/5589/(265895&&)0(+86(2(+(+
@4GV
TTGAAAAGCAAAGGAACACTTTTTCATTTGCTGAAAAAAAACTTTGAAGTTAACTATCAAGAGTTACAAGAGGAGTATGCTTGCCTTCTCAAAGTAAA
+
@CCFDFFFHHHHHGGHGJIIJJJJIGIJJIIJJJJIJIJJIIGIEIJIECHHJJGIIIJIIHHHHHFEDBDDDAD;>>C@DEDDDDCCDDEDDD>ACD
@4GW
CGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGG
+
BC@FFFFFHHHHHJJJJIIJJJJJJJJJJJJJJJJJJJJJJJJIJIJJJJJJJJJIJJJJJJJHHHHHFFFFDCCEDEEDDDACDDDDDDDDDDDDDDDDD
@4GX
CCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJHJJJJJJJJJJJJJJJJIIJJIJJJJJJJHHFFFDEEEDDEDEEFEEDDDDDDDDDDDDDDDDC
@4GY
GGAACGGGGCTGTTCATGGGACCAAAGCTCTTACCATATCTACTCTGAGACTGAATGTAACCGAATGGGAAAACAACATTCCTTCATGCTTTCTGGATCCC
+
:+1+=@@)00<<<22CEEB+)1)1C;D)?9D9?9*9BB4*1*?B<?C)=))/8@/))/))))--',)).(.((.;,,(,(((,:A((((((5(5((+>4<9
@4GZ
TTTAGAGTTGACAGAACAGAGTCAAAAATTACAGATTCAATTTCAGCAATTACAGGCTAGTGAAACTCTGAGAAACAGCACTCATAGTAGCACAGCTGC
+
?@@DDFEDBFDFDBGBEHIEEHCHGGHIIEHIJJJJGEHHICHFFGDGGHHIHIIGGFD>FGHIGEGCFGGF=CH9D;;==EED>DF;@AC>ACCBD>?
@4H0
CCAGGCTCTGCAGCCACATCCGACCGAGTCGTCCATGTACAAGTACCCTTCTGACATCTCCTACATGCCTTCCTACCATGCCCACCAGCAGAAGGTGAACT
+
-0(((2(2=..))22:@?@<9=55=/7(83--075.)>)>3>?.;3>;?>;136).<)..9.;336=89=83;<;;9<3((3;;;5/((+2622/++:526
@4H1
GGATGACGTAGCCCAGTGGCTCAAGTGGGCTGAAAATGAGTTTTCTTTAAGGCCAATTGACAGCAACACGTTTGAAATGAATGGCAAAGCTCTCCTGCTGC
+
CCCFFFFFHHHGHJJJIJJJIJJJJHHJJJJJJJJJJJJJFIIJHJJJJJJJJJJJJJIJJJJIJJJIHHEEFFFFDCEEEECDDDDDDDCDDDDDDDDDD
@4H2
TTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGC
+
=@=DDDDFDD2CFBGGGGBHHIADFGHCEBG?FH>FAD>FBBGGIGBBHBGIBE@F;FGGEEGAECAE?BBDBDE6;@C@CBBCC?C9:5>ACB?A9<12<
@4H3
TATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTC
+
@@CFAEFFGDDDHIEHGIGEGHGHGJJJBFFIIBGECFHGEGGGIIIIJHHHJIEHEHCGGCGDGGFHFDF@D?BDDCCC<CCBDCDCB5@CCDCCCD@C
@4H4
CCTGCTGCTGACCAAAGAGGACTTTCGCTATCGATCTCCTCATTCAGGTGATGTGCTCTATGAACTCCTTCAGCATATTCTGAAGCAGAGGAAACCTCGG
+
CCCFFFFFBFHHHJJIIIJIEHIIIJJJIJIJIIJGGIIGIGFEIAFIBFIIIFFGIJIJIIIIJGHIJIHHGHHGFFFFFFFEEEEECBDDDDCBDDDB
@4H5
NTCAGCTTGGACATCAACAAGCTCCCCGGCGAGAAGCTGGGCCGCGTGGTGCACATCATCCAGTCACGGGAGCCCTCCCTGAAGAATTCCAACCCCGACG
+
#11=:2=BBD?CBEFFEFG=C3A<<<?CGFG?76@@;=@=@;==8939858AB:>:5@5@:A:+4(+00005;8?38???>@>@:3>>BB>@><9<9&05
@4H6
CCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCGAGCCCACTCAAGGATATGCACAGACCACCCAGCAGGCATATGGGCAACAAAGC
+
@@@DB:A;=??D;FADE@<AFB:1?;@86):BB*99*9BDFFB9''5'-:???BC9@A>>ABB355(;:(5358<28-(++<?8<B>@@BBBBBB1?B2(3
@4H7
CTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGC
+
CCCFFFFFHHHHHJJJGJJJJJJJJJJJJJJJJIIJIIJJJGGGIIJJIJJJJJIJJJGGJJJJJHHHHFFFDFFEEEEEEEDDDBDDBBDDCDDDDDDD
@4H8
CTGGGAAAGGACCTAAAGGTGTATATCAAATCAGCAAACAAATCAAAGCTCATGATGGCAGTGTGTTCACACTTTGTCAGATGAGAAATGGGATGTTATT
+
@@@DDBDDHFDDFHEGBGH<C::?EHIIB>AFEHEHDHHHHG@BG<B?GBF39D?BBEG@F)88@@FH;C)@GCEHEECE@DE;;>CCCCCB?;?@CDEC
@4H9
CAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTC
+
@?@DDD:BFFBBFFBDBD:ABAEFECA;FECBAFFF@BFBGEFF?FEDFI??BBFE@;CF-=CDEFFFE>BBDDDBCB@A@@B>AB>?@9<:@BA5:<?><
@4HA
CCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATG
+
CC@FFDDFDDH>FBGGIGIGIIBEHIIGICH@GGGIBEB*?DHGEHGIGIIEIEHC=BCABEAAEHFFEF>>CEEECEDB8=?BB?BBB?BDB?CACDDEC
@4HB
CAAAGTGGATGCGGCCTGCAGACAGGATTGCCCGCTTTGCCGAATCGTGTTGGCCGGGGAATTGGGGGCGAGGCGGGGTTTCCTGCGGGAGGGCCGCGAGG
+
0(((2.)4).)(058;((2)))((.(:8)0)))09(((0))''';9(.((..()),'''''(((,/5&&&&))&&&&5&)(8652(&&&&&&002&5-)&&
@4HC
CATGGTTGGCAGTGCGGCCAGCCAAAGCTTTCCCCCTCCTCTGATGATTAAACAGGAACCCAGAGATTTTGCATATGACTCAGAAGTGCCTAGCTGCCACT
+
CCCFFFFFHHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHHFFFFDDEEEDDDDEEDDEEDDDDDDDD@ACDDDDDDDDDDDD
@4HD
CGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCA
+
B@BDF@DFFHHHHIGGGIGIIJJJJJIIJJJIIJJJJJIJIIJJJJJIIIJJFJJHHHGHFDDDDDDDDDDDDDDCCCDDDDDDDDDDDDDDDDDDDDD
@4HE
GGAGCGGCAATTCACTAACAAGAAAACAGGGAATTTTTGGGAAATATGAAAAGCCAAAATTTGTGCAGTGTTTAGCATTCTTGGGGAATGGAGATGTTCTT
+
CCCFFFFFHHHHHJJJJJJJJJIJJJJJJJJJJJJJJJJJJIJJJIJJIJJJJJHHHHFFFFFEECEECCEEDDDDDEDDEEDDDDBDDDDDDDDDEDDED
@4HF
ATTGTTACCCAGTGGTGTGAGGGCTCCAGCTTGTATCACCATCTCCATATCATTGAGACCAAATTTGAGATGATCAAACTTATAGATATTGCACGACAGAC
+
+:=AAAAAAA>C@@A+<?<C<73?C=2@A7@@>BA?AA73?B=BAA=AB??B??ABBBB<>BB>ABBAA=AA;;=AA@>@?@@@>>;>@>>;;3;=6==?=
@4HG
GCCCTCTCTCAGCCCCAGCAGAACAAACCAAAGAAAAAGGAGAAAGACAAGAAGGAAAAGAAAAAAGAAAAGCACAAAAGGAAAGAGGAAGTGGAAGAGA
+
CC@FF@FFHHHHHJJJIJIIIGHIIGICHHIGHIBGGCHIIJJJIHHGGHHDFHHHIGIEEHHHFDDDDDDDBCDDDDDDBBDDDCDBABD:ACDDCBDC
@4HH
CGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTT
+
@CCFFFFFHHHHHJJIJJJJJJIIIJIIJJJJIIJJGHIJJJJJJIIJJJJJJJJJJJIHHHHFFFFFEEDEEDDDDDDDDDDDD=@CDDDCDCDD>ACDD
@4HI
TTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJIGJJJJJJIIJJJJJJJJJJJJJIJJHHHHHFFFFFFECEEEEDDDDDDDDDDDCDDDDDDDDD
@4HJ
GGTTTCGCCGGCAGTCTCGATGATAGTATTTCTGCTGCAAGTACTTCTGATGTTCAAGATCGCCTGTCAGCTCTTGAGTCACGAGTTCAGCAACAAGA
+
@@?DBB;:8C@CFEHIG<?:DD??FH?FCF<FFGIIFIIGGBCAFEBAF;FG=@FCCCGE4=;ABDDC>@@3@@CCC@>;@@B8888>;:5:?B??<C
@4HK
TCTTTGGAGCCGCATCACAATACTGGACCTCCCCCACGGGGGGAATCTACCCCAACCCCAACGTCCCCCGCCATCCTAACACCCACGTGCCTTCACACTT
+
@CCFFFFFHHHHHIIJJIJJIIIJJJJJJJJJJIIJJGIJIFDDBDCDDDDDDDDDBDDDBBBADDDBD;@DBBDDCCDDCDDDDBDBDDDCCDACDDDD
@4HL
NTGTCTGAGACTCCTGCTCAGTGTAGCATTAAGCAGGAACGAATTTCATATACACCTCCAGAGAGCCCAGTGCCGAGTTACGCTTCCTCGACGCCACTTC
+
#1=DDDFFHHHHHJJJJJJJJIJGJJJJJJJJJIJJJJJJJJJJJJJJJIJJJJJJJJJJJJIJJJJJIHFHGGFFDDDDDDDDDDDDDDDDBDDDDDDD
@4HM
CTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGT
+
CCCFFFFFHHHHHJIIJJIJJJJJJJJJJJJJJIHIJJJJIJJJIJJJJJJJJJJJJJJIIHJJIJJHHGHHHFFFFDEDDDDDDDDDDDCDDDDDDDDDD
@4HN
GTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTAC
+
CCCFFFFFHHHGHJJJJJJJJJJJIIJJJJJJJJIJJJJJJJJJJJJJIJJJFHJJJJIJJGHHHHHHFDFFDEEEEEDDDDDBDBDDDDDDDDDDDCDED
@4HO
GCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGT
+
@CCFFDFFHHHHHJJIIIIJIIJJJGIIJJJJJJIHIJIJIJJJJJIJJJJJJJJIJJJJJJJJJJJHHHFFDDDDDDDDDDDDDDDDDDDCDDDDEDDD@
@4HP
TGGACGGTTTCGCCGGCAGTCTCGATGATAGTATTTCTGCTGCAAGTACTTCTGATGTTCAAGATCGCCTGTCAGCTCTTGAGTCACGAGTTCAGCAACA
+
;@<DDADDBAFHFB6F>ED?BDGGGHGGGICHACGGIA@EEFFHHI=@ACC@AE>>A?CCDEED77;;9>@CCC@CCCCCCCCCCCCB?B8@CDC:CC<B
@4HQ
GACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTG
+
=?@DDDDAFHFBDGIIHGIIIFIIE:F?FGIIIIGHGIIIIIIGICHHGGIEEGIIIIHHAEEEDEEEEDCCCCC?>AC??=;@<<A@CCAC>CB?@BBC<
@4HR
CCTCAGTCCTTACTATGGCTCAGGAGGTCAGGATAGCCTGTGAGGATCGAACCTGCTCCGTGCGGGAGCAAGAGGCACCAGCAAACTTCCAGGTCCAGCTG
+
0-0(2;@1)<)2))))))3:)<)8.(3973:1))))..)(0)))(9))((0(').;631'.;'',9'39/7((875((+28((2+2(((43+(++((+(+2
@4HS
ATTACTTACACGCCAAGTCAATCATCCACAGAGACCTCAAGAGAAATAATATATTTCTTCATGAAGACCTCACAGTAAAAATAGGTGATTTTGGTCTAGCT
+
@@@A?ADDHDBHAED@EHBHBFHCHICCFEEG*:?CAFB@?BD)9DGGDDG>FFC=FHGI@FCGGIEDG@7=AEHHHFBDEE;@C(6(;@DC;??>@@C<C
@4HT
CCCACTAGTTACCGACCCCAAACTGGATCCTACTGCCGAGTGCCGAGTCAATAAAGCCAACACCGGAGCAGCTACGGGCAGCAGACTGCATCAGGAGAT
+
=+:2AA;+@,,<A1))?87?+=A3**11:ABAB****)0((().'-4-)).)))..>@3)=(,(''',,((5+8:3;&050(8((++(38(3(+33988
@4HU
CCTCCACAGCCCATCATGCCTTCAGTATTCTCTCCAGACAACCCTCTGATGCTCTCTGCTTTCCCCAGCTCACTGTTGGTGACAGGGGACGGGGGCCCTTG
+
????DD;?=?DD:AEEI4F?A<F<A2ACFEFIACEED3:?3BDI>=DE>D>4*BB>@CA@BCCEID;@;AD3?ACACDD(;;@>>>=;8??:9>;>7;1<<
@4HV
CTGGATGACCCTTCAAATTCTCATTTTATTGCCTGGACTGGTCGAGGCATGGAATTTAAACTGATTGAGCCTGAAGAGGTGGCCCGACGTTGGGGCATTC
+
CCCFFFFDFHHHHJJJJJJGIJJJJIJJJJJIJJIJGIJIJFHIIJJGIIIIIJJGIJJEIJJJJIIFHGGHFFDFDED>ADDDBBB@BB?BDDDDBCCD
@4HW
GTGAGCCCCCCCCTGAAGGCAACTCTACCAGCGCCCTGACACAGAAACTCTTTCCTGTCTTCTTATCCCAGTGCTTCGTTCCCTGGCCCGGCTGATGCCCC
+
553=?7@((((<-(-)0:7(:(09).)0361(''5'-.8383==;=(.(:(((7;1(-(,:=2;;=((,7;26/2:85((+3:+((28(&))&)((+(+8(
@4HX
GGATGCTTCAGCTCATCTTAGGCTGTGCTGTGAACTGTGAACAGAAGCAAGAGTACATCCAAGCCATTATGATGATGGAGGAATCTGTTCAACATGTTGTC
+
@@CFDDEDDHHHFFIGFGIGDFHG;EFBEHBBHEFCBHC9G>FGIIIGD@GDF9?DBDH?FHEGECHI@GH>GC;DAHHGE;?@@DBCC>AD>>=C>CCCD
@4HY
CCCAACTACTGCTTTGCTGGCAAGACCTCCTCCATCAGTGACCTGAAGGAGGTGCCGCGGAAAAACATCACCCTCATTCGGGGTCTGGGCCATGGCGCCTT
+
1:14BA2ADBDDD<A:A2C<FFII;<<<FC9C;1*::DDE>?DBB0BBDDC0(888;';:?<?=;;?::(><<?=25>:>?>9&)(++((+++:><>&)09
@4HZ
AAAAAACCTGAGAACTTCCTGATCTCTCTCGCTGTGAGACATGTCTGAGACTCCTGCTCAGTGTAGCATTAAGCAGGAACGAATTTCATATACACCTCC
+
@CCFDFFDHGBDHCIIAFHCFEHGHIIIGIE@FF@DGCDCGG@FFGHGFGDHIICGHIIIC@DDEEHIEFFHFHFFDFEAAB;==CCACC@DDECCCCB
@4I0
CTTTCTTTGTGTTTCTTGTTCCATTCGTTGTACTATATCAGATTCGAACTGGCTGTCTTTATGATTTCTCTTCTGAAGTTCTTCGACTGTCCCCATTAACT
+
1:7A<722+2<2@=C@CB=>C?CB<CACBBC9A?BB@=:AA*111:A>BA<9A=89??=B*.8ABB<>B>)/.)8.>==A7==76(=<<......5;=55;
@4I1
CGAGCAGCTTGCAGCCCTCTCTCAGCCCCAGCAGAACAAACCAAAGAAAAAGGAGAAAGACAAGAAGGAAAAGAAAAAAGAAAAGCACAAAAGGAAAGAGG
+
CCCFFFFFHHHHGJJJJJIJJJJIJJJJJJJJJJJJJJJJJJIJJJJJJJJJIIJGIJHHHHHFFFFFEEEEDDDDDDDDDDDDDBDDDDDDDDDDDDDDB
@4I2
AGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAAC
+
@@@DDFFDBFHHFIGGII@IHGGCHHGIIIDHIIIIIIIIIICHIIIIFFGGEHH>HIIIIIIIIHHHEHCD@DFFFCECE>CCBCCCCCBCC>CCBCCBC
@4I3
GACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTG
+
CCCFFFFDHHHHHJJIJDHIJIJJJJJJJJJJIJJJIJJIJJIJIIIJEIJGIJIJJIHHFHHHFFFFFDEEEEEDCDDDDDDDBBDDCDDDDDBDDDDCB
@4I4
CTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJGHIJJJJJJJJJJJJJJHHHHFFFFFEEEEDDDEDDDDDDDDDDDDDCDDDDEDDDDDDDDDDDDDDD
@4I5
CACAGAGACCTCAAGAGTAATAATATATTTCTTCATGAAGACCTCACAGTAAAAATAGGTGATTTTGGTCTAGCTACAGTGAAATCTCGATGGAGTGGGTC
+
C@CFFFFFHGHHHJJEGAFCGHIIIJJJJJJJJJJJJJJJJJJJJJIIJIIJJJJJJJIFHIJGIIIJHIIJJJJJJJJHFHHHHHFFFDFEDCBABBDBC
@4I6
AGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCAC
+
CCCFFFFFHGGHHJJJJJJJJJJJJJJJIJJJJJJIJJJJJIJJJJJJJIJJIHHHFFFFEEEBCEEDDDDDDDDDDDDDDDDDDDDDDDDDDDDDED
@4I7
CCGGGCCTTCCCAGCTCACCTCCCTCCATCGCAGTCCATACCAGATAGCAGCTACCCCATGGACCACAGATTTCGCCGCCAGCTTTCTGAACCCTGTAACT
+
?=@718@B?<?::+<<AAAEFCC;FFIEFDEAGD6BBGEIFCD>;C4C>B4@@7=EEE=AFFE?B.;?@>;;;@=6??@B<<BAB:@>:4:3<BB<B>A::
@4I8
ATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCC
+
@@@FDFFFFHGHFIJIJIIJJGIIIHIJGIIIJJGIIJJJJIJJJEEBBAGGHIDEHHDEDE?BCDDDDCDDCCDDDDDDDD@CDDDCDDDDDDECDDD
@4I9
GCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACC
+
CCCFFFFFHHHHHJJJJJJJJJJJHIIJJJJJJJJJJJJJJIJJGHIIHIIIIJJJJJJJJIJJJJJJHHHEEFFFFFEEEEEDDDDDDDDDDDDDDDDD
@4IA
AGAAAACCAAGTCATACCAGTGCTGTCTCAATTGCAGGAAAAGAAACTCTTTCATCTGCTGCTAAAAGTGGTACAGAAAAAAAGAAAGAAAAACCACAAGG
+
CCCFFFFFHGHHHJJIJJJJGGGGIHIIJJJJJJGEIIJIJJJJJJJJJJJJJIJJJJIIIJJJJJIJGHIBEIJJHHHHHFDDDDCCDDDDDDDDDDDDD
@4IB
GGAAAGTGAAATTTCAACCACAGCAGATGACTGCAGTTCAGAGGTAAATGGTTGCAGTTTTGTGATGAGAACAGGAAAGCCTACAAATTTATTAAGGGA
+
CC@FFFBDHHHHHJJJJJJJJJJJJJIJJJJJJJJJJJJJJIIJFHIIJJIGHJJJJJJJJJHHIJJJJJJJJJHHHHHFFFFFEEEDDEDEDEEDDDD
@4IC
CGAAACCTGGCCACCAGGAACTGCCTGGTTGGAGCGAATCTGCTAGTGAGGATTGGGGACTTCGGCATGTCCAGAGATGACTACAGCACGGATTATTAC
+
939(-8>.=3>1)(2.2(;:>>;))))8).1=3=13-==?).)/:8;>6)<)).<:75(,3)6==8/'(-7;82(,(,8((2,62(((()55-0226=;
@4ID
CTTGAAGCAGAGAATAGCATTCTTAAAGATGAAAAGAAAACCCTTGAAGACATGTTGAAAATACATACTCCTGTTAGCCAAGAAGAAAGATTGATTTTCTT
+
@BCFFFFFHHHHHJJIIJIJJIJJIIJJIIJIJJJJJJJJJJIJJJIIJJJJIJIJJJIIJJJJJIIJIIIJJGHGFHHHGDFFFEEEDEDDDDEDEDEDD
@4IE
AGACAGGAATCGAATGAAAACACTTGGTAGACGGGACTCGAGTGATGATTGGGAGATTCCTGATGGGCAGATTACAGTGGGACAAAGAATTGGATCTGGAT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJEHIJJJJJJJJJJJJGHIJJJJJJJJJJJJJJJJJHHHHHFFFFEEEEEEBCDDDDDDDDDDDDDDDDDDDDDD
@4IF
CTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJIIJJJHIJJHHHHHFFFFFFEEEEDDDDDDDBDDDDDDDDDDDDDDDDD
@4IG
GCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGT
+
?<:ABDBDBAFFFHHD>GEE<GI@GFFGHC<CFE>HD@FHFDCHGEHGIGGHDFGFCDF=FHGGIIIF;CFFCABCBA@CCCACC<9CBCBCC@CCCCCC>
@4IH
CAACCACCAGGAGTCCTACCCTCTGTCAGTGTCTCCCATGGAGAATAATCACTGCCCAGCGTCCTCCGAGTCCCACCCGAAGCCATCCAGCCCCCGGCAGG
+
@@@D?D;B;<D;<F;?4AE;AFHCB999?1?1??FA?GBG>F>@BB??F<B??B?F===@A1;BA=E8B4BCC@;;;8>882;?(+32>CC??5@5<>59.
@4II
GAAGAAATTGCTCAAAGATGCCATGAACTGGATATGCAGGTTGCAGCATTGCAGGAAGAGAAAAGTAGTTTGTTGGCAGAGAATCAGGTATTAATGGAA
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJIJJJJJJJFHHGIJIJJJJIIIJIJJIIIJJIJ=CGHIIJIJHHHHFFFFEEEEEE;@CDDDEDDDD
@4IJ
CCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAG
+
CCCFFFFDHHHHHJIIIGIJJJJJJJJJJJJJJJHIJJJJIGJJIJJIJJJJJJJJJJJJJJJJGHHHHHFFFFFFECEEEDDDBDDDDCDEEDDEDED
@4IK
GGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCCCTGGTTATAC
+
+:??DA?BDDDD:CEB<AF:CC<CBB4CF;?BDDEIED;D@D<<BB>D9DDCC2@;<@=@'''59);A>>(6>>>AA5;(-::((5,,9=&09<<(4>:>:
@4IL
CAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGC
+
?@<:1BDDDHHDHHI=FHGHCEHHBEB):?CD?FDGGH<DGIGEIII<CEACBGHCH;DHCHEC=@EEC>ADBDD>CAB?BC;9?CCCCACCCCACCCCCA
@4IM
AATGAGGCCCTCCAACCCCCCCACACCATCCAGCACGCCAGTGTCCCCACTGCATCATGCATCTCCAAACTCAACTCATACACCGAAACCTGACCGGGCCT
+
@;=DD?>DHFFAFHIIIFIGIDFHGICIIGI@DHCH;AHIHAEACDDFFD>CEDDCCCDDCCCCCDDC@BCDCCCCCDCCDCDDBBDDDD3<?CCD<<B>8
@4IN
CACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCT
+
C@CFFDDFFHGHFEHIIDHGHIIGGHEGIIIIIGII@DGGGIIGGDEAGHGHIEHHHGFFFFFCCECCECCCCECCCCDCCCCCCBCCC:@ACCCBBBBBB
@4IO
CCTTATTCAAACATCAACAACAGGGACCAGATAATTTTTATGGTGGGACGAGGATACCTGTCTCCAGATCTCAGTAAGGTACGGAGTAACTGTCCAAAAGC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJFHIJJJJJIJJGJJHHHHHHFFFFFFEEEDECEDDD>CDDDBD?CDDEDCDDDDDDAB
@4IP
GTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCC
+
@?@DBDFF?DHFFGGIIIGCHFGHICDDGGGIIEI?DBFHIIIEEE@EEGEEEEDF@CCBBCEEEDEADCCC?CBC>AACCCBB8?9ACCCCBBCCCCCCB
@4IQ
ACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGT
+
@@@FBADFDHHHHGI@EHA@8FEGGDGGIIFEHIIIIIIICHIIIIICHIIIIIIIIGHHHHHFFFBECEEEEEC@CCBCBBBBBBCCC>>ACABCBBCB@
@4IR
CACCATCTGAGCTGTCCAAGATGGCCGGCGAAAGGAGTGTTCCGAAGACAGGAGCGGCGATTCGAGTCAGAGACGTCGAAAGGGCGGAGAATACAAGCGAT
+
7(((2))2.)4)))2):>?4(8)3)2(((00(7<(.:)(8)6.''75'6.8((,(,;75&&(((+(+++8:((((())&(+&((()&0&5(+88:<<(2(2
@4IS
CATCCCCTCAGTCCTCACCATGCCTCAGGAGGTCAGGGCAGCCAGAGAGCATCCCACCTGCTCCCTGCTGGAGCAAAAGGCCCCAGCAAACTTCCATATCC
+
@@@FFDFDDFHBFHDFGGDHEEHEHDIIIIIIFHECGHGGHII;BDDDHHIDHIIIII@@C)=?ECCDDDD26;;?CC?BDB?B@@BD??A::ACC@@ACE
@4IT
CTGTGTCCAGAGGACCCCCAGGCCATCCGTGGATAATGTGCACCATAACCCTCCCACCATTGAACTGTTGCACCGCTCCAGGTCACCTATCACGACAAATC
+
?;=ADDBDDFHFDHIGDHGBB1CGHIGHG1B@GEEFHIBBEGHGFDGEIGIIDCDGHBCAAEEEDDB;;BCCACBB:=?:@C(:@CACCACCC@@<@BCAC
@4IU
ACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJIJJJJJJIIJJJJJJJJJJJJJIJJJJHHHDBDDDDDDDDDDDDBDDDDDDDDDDDDDDDDDDDCDDDE
@4IV
ACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJIJJJJJJJJJJJHHHHHFFFFFFFEEEEEDDDDDDDDDDDDDDDDD
@4IW
CCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGT
+
@CCFFFDFFHHHDHIIBGHEFGHIJJJIGGGHIGIIJJIJJHIGIIGCGIJJHHHFHGDFFFFFDDCCEDDBB>ACDDDDDB?BACDDDDDCDCDDDD??:
@4IX
AGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCAC
+
CCCFFFFFHHHHHJJJJJGHIIJIIJIJJBGHJJJJJIIJJJJJJJJJJJJJJJJIIJJJJJJJJHHHFFFFEEDEEDDDEDDDDDDCDDDDDDDDEDDDD
@4IY
CGTGCGGCTGAGGACGATCCGCCAGTGAGCGCGGAGACTGCTTCCACTTCGGGCGGGGGAGCCCCGGACCGAATCGGCTCTCTAGGCCGTGGAGCTTGCCG
+
BCBFFFFFHHHHHJJJJJJJJJJJJIJIJIJJJJHFFFEEEEEDDDDDDDDDDDDDDDD@BDDDDDDDDDDDDDDDDDDDDDDEDDDDD@BDBDDDDDDDD
@4IZ
AGGATCTATTGTACTAGGCCCATAAGTAGTTTCTGTTTCCACAACTGAAAACCTCAAACAACAGCCTTACTCAGGAACAGCAACCACCGATCTAGCTATAC
+
0-0:()))))2..).))4))28))3)32))2)):)))2)).)8(:)0)))..9))))0<7((..(.))))8).)))(.()(..6(3,(',',((((,(++(
@4J0
AAAAAGACGAAGAAAAATAATAGCAGCAACAGCAATGTGAGCAAGAAGGAGCCAGCGCCCATGAAGAGCAAGCCCCCTCCCACGTATGAGTCGGAGGA
+
7@<ABD?DF@@D?EGEDE?DCBHHEHHGIIIIGEEHIFHGHGIIIHHDGBFGGC=CEGHFDEBDCCCCCCCC=???@BBBBCA@BCCCCC4>>>.<@<
@4J1
GGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCC
+
CCCFFFFFHHBHFIJJJJJJJJJJJJJJIEEGGIIJJJIIIIIJJJFIJGIJEHFEHEFFFDFDCEDEDCCDCDCCCCDDDDDDBDDD9>ACDDDDDDBDD
@4J2
GTCCACTTGTGGAAGAGGAAGAGAAAGTGCCTGTGAGGCCCAAGGACCCTGAGGGGGTTCCTCCTCTCCTGGTCTCTCAACAGGCAAAACGGGAGGAGG
+
CCCFFFFFHCFHFGHFHHFGGDHEHEEAFHIJIFGHIEHJIGIJIDIIIEHGIGIEHDBEDEDDDDDACDCD:ACCCDDCCDDDDDD?CA@?B9>B??@
@4J3
CCAAAGTGCACGGCAAAAGATATGCTTACAAATTTGACTTCCACGGCATTGCCCAGGCTCTGCAGCCACATCCGACCGAGTCGTCCATGTACAAGTACCCT
+
8+1A?B,=+A?2@<?@;3A+<+<9CEE>C<4*:CD@<00?09BD;D<;ABB@C@D;(6@A777=?A6;>@@A;3;,3,'5(()2888::4>:B>>4:AA:A
@4J4
TGCCTCCTGAGAAGCTCAAACTGGCGTGGGCATATGGTTATCGAGGAAAGGACTGTAGAGCTAATGTTTACCTTCTTCCGATCGGGGAAATAGTTTATTTC
+
11+27@3<2ACBBB==@B7ABA+3+)1:?8;)?:?70=?*:=5(/0'==52(.)6A4)..)=A>.).7;7>>@>>3((6,',''''&00;(33(388::;:
@4J5
CTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGC
+
CCCFFFFFHHHFHHIIIIJJJJJJJJJJIJJIJIJJJJJJJIJJJJIJIJJJJIJJJJIJJJJJJEHHFDEFBEF(>@EEDEDDDDDDDDDDDDDCDCDD
@4J6
CACGCGTGATCCAGCTGATGCCCAGCCCCATCATGCACCCTCTGATCCTGAACCCCCGGCACTCCGTGGATTTCAAACAGTCCAGGCTCTCCGAGGACGGG
+
;??A?DDDHD8FBADGC<HDB<@GGGFHGIIEEGGDHIG@GGEFGGHFHGIIGDEGBBDCA?CCCB<?@BCCCCDCC:<ACA@C:382<AC?@@@B@BBB<
@4J7
CCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGAT
+
CCCFFFFFGHHHGGGHGIIJJJJJJIJJIJIGGIJIIIEEEHIABGEHIIGFFDHGHIGIIGIHGE9EEHCEDDFFF@CCECCCDDDDDD@9A?=>BBB?>
@4J8
CTTTGGAGAAGTGTATGAAGGAACAGCAGTGGACATCTTAGGAGTTGGAAGTGGAGAAATCAAAGTAGCAGTGAAGACTTTGAAGAAGGGTTCCACAGACC
+
1?<B?DDAD82,<CBB4,3<3AAFEC8A22@3?3C9B@CC>90?)00*B*9BDCEDDDEECDCC=.=;AC7.7=@?)=A>??AD)?;6>'6;=3;>>=><?
@4J9
CAAAAATGAAGTAGGAGTACTCAGGAAAACACGACATGTGAATATCCTACTCTTCATGGGCTATTCCACAAAGCCACAACTGGCTATTGTTACCCAGTGGT
+
CCCFFFFFHHGFHIIJJIGIJJJJJJJJJJJIJJGIIJBGIIJJIJJJIIJJJJIJIJJJJJJJJJJJJJHHHHFDFFDDEEDDDDDDDDDDDDDDDACDA
@4JA
NTTGAAAAGGATACAACAGAACTCATGGAAAAACTTGAGGTAACCAAGCGAGAGAAATTAGAGCTGTCACAGAGACTGTCTGATCTTTCTGAACAATTGA
+
#1=DFFFFHGHHHJJJJJJIJJJJJJJJJJJJJJIJJIJJHGIIJJJJIJHIIJJJIJJIIIIIHHHHHHFFFFFEEEEEEDDEDEDDCDDEDDDDDDDD
@4JB
GACGAGGAGAGACAGAAGAAGCTGGAGGCCGGCAAAGCCAAGCTTGCCCAGTTTCGACAAAGAAAAGCTCAGTCGGATGGGCAGAGTCCTTCCAAGAAGC
+
B@@FFFFFHHHHHJIIGIGHGGGIHJJGIJIFHIJIJJJJJIJIIIIJHFHHFFFFFACDCCCDD?CAACCCACDDDDDBBDDDBD>@CDDDDDCCBDDD
@4JC
CGGACCTAAATTCGCTCATTGGATACTCTTCAATAAGGCAGATAGCGCGCGTAGTAGCATCCAGTCTCTCTCAAACCCCCGGAAGCTGAACCTTGGGAGCC
+
7((((()2..)).(8>(-2>@))2..=))=)):)):)))(((.<))--''--9',:)((((.(--((7(((,(,,(7;<-&5::-8</(826((((((+&(
@4JD
CTGGCTATTGTTACCCAGTGGTGTGAGGGCTCCAGCTTGTATCACCATCTCCATATCATTGAGACCAAATTTGAGATGATCAAACTTATAGATATTGCACG
+
CCCFFFFFHFHHHIJJJIIIJEGEHJGIGIGIIIIJJJJHJIGFIIJIJJJJIIIJJIJIJJJFHGIIIIJHHGHHHFDDFFFEEEEEEDCACDEEEDDDD
@4JE
CTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTC
+
CCCFFFFFHDHGHIJJJIGGHIIJJJJJIJJJJJJJJJJJJJJJIIJIGIIIHHGHHHFFFFFFFEEEDDDD@CCDDDDB?BDBDDDDDDDCCDDDDDDCC
@4JF
CACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTC
+
CCCFFFFFHHHHHJJJJJIJJJJJJJJJJJJJJJJJJJJJJJCHIJJJJJJIJHHHHHFFFFACEEEEDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDD
@4JG
GGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGT
+
<@<BDDADHHHH?ECFHDHGHHHEDHIIIIICFEGFDHDGHEHGGII@BECHICHECBDD=?@AECCCCCCCCCCCCCC>,>@@CC3(>4>ADCCC@C<?4
@4JH
CCCAACCCCAACGTCCCCCGCCATCCTAACACCCACGTGCCTTCACACTTAGGCAGCTACTACTAGAAGCTTACTCATCAGTGGCCTTCTAGCTGAAGCCC
+
CCCFFFFFHHHHHIJJJJJJJJJJJJJJJJJJJJIJJGIJJJJJJHHHHHHFFFFFDEEEEDDDDDDDDDDDDDDDCCDDDCDDDDDDDDDDDDDDDDDDD
@4JI
GTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGACTGCATCAGGAGATATGCAAACATATCAGATCCGAACTACACCTTCAGCTACTTCTCTGCC
+
@@@FDFD:C?FHHDHIEGIIFGDHG@@FGIGIEIGGIGIGIEHE<FC==CBFHIIGGHGIGGEHC=EHFDF@ECCCBCC@?CCCCCACC>CCCCCC>CCC
@4JJ
CCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJIJJJJJJJHHHHHHFFFFEDCEEEDEDDDCDCDDDDDDCDDDDDDDD
@4JK
AATAATAGCAGCAACAGCAATGTGAGCAAGAAGGAGCCAGCGCCCATGAAGAGCAAGCCCCCTCCCACGTATGAGTCGGAGGAAGAGGACAAGTGCAAGC
+
@C@FFFFFHHHHGIJJJIJIIIHHIJIJIJJJJJJIJJJJJJJIJJJJJJJIIJJIJJJHHHFFFDEEDDCDDDDC@@D:>@@BDBBDABDDDCDCDDDD
@4JL
CGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCC
+
@@@DD;DAAFDFA)@A@@E81?F?B8??B@GEBDGGF?@6CFF6ABFECEFFE>B>BD@B>;;=?A>?BA>;=@BBB@?9<@BBBB3>@AB::AAB<BBB
@4JM
GGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCAC
+
<@@FFFFFBHFDFIG?CGHIIFGGHGGG@HCFHB?<A99BDFAHGGICHEGBG4:?;;<;;@@@ADDDCACCDACBD?B@BDD<AB8?CCCD8>C@C:AC
@4JN
CCACCGAGACATTGCTGCCAGAAACTGCCTCTTGACCTGTCCAGGCCCTGGAAGAGGGGCCAAGATTGGAGACTTCGGGATGGCCCGAGACATCTACAGGG
+
7==7AAAA7ACB>BB?BCBB3CABBBB<AABAB?==?A?AA>=7==AA<ABBBB2;(;:AA@@@>>>>>;;5,---8==='58;99;;9;=<;;;=(388+
@4JO
CAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTC
+
C@@FFFDDFFHGFIEGHIGIJJJJIJJIJIFIGGGGGJHIIJJJIJJIJJFGGGHJJIHGGIIJJJHFGFFFFFFEEEECEDDDDDCDDDCDCDDDDDDDD
@4JP
GACATCTCCTGTGACTCTCACCTCTCAGACAACTAAGACAGATGACCCCCAATTGAAAAGAGAAATAAGGTTAATGAAAAACAGAGAAGCTGCTCGAGAAT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJIJJJJJJJJJHIIIJJJJHHHHHHFFFFFFEDDEDDDDDDDDDDDDDDDDD
@4JQ
CGCATCACAATACTGGACCTCCCCCACGGGGGGAATCTACCCCAACCCCAACGTCCCCCGCCATCCTAACACCCACGTGCCTTCACACTTAGGCAGCTACT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDBDD?BDDDDDCDDDDDDDDDDDDDDDC
@4JR
CTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJHJJJHHHHHHFFFFFDDEEDDDDDDDDDDDDDDDDDDDDDDDDD
@4JS
CCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGGAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCAGGCAGCCAGT
+
??14ADD>BD,<2ACEEBE6)0?9D<DDD=)6BBBCCD<C@>=)=)=;)@;@=(62??;);6(;6;;>-5==7((:5(:?=(,&8>(9>8((((++28(2(
@4JT
GACTGCACAGGGCATGGATTACTTACACGCCAAGTCAATCATCCACAGAGACCTCAAGAGTAATAATATATTTCTTCATGAAGACCTCACAGTAAAAAT
+
@CCDFFFFGHDFFGGIGFHHIIGGIIJIJJGIJGDBGGGIJIJJIJFGIJIIJDGJIGGC@DHIJIGFGHEHHHHFFFFFFECEDEEDDDDDCDDDCCD
@4JU
GGAATCATCACTTAGAGCAACTCAACCAAGTGAAAATGATAAACTTCAGAAAGAACTCAATGTACTTAAATCAGAACAGAATGATTTAAGGCTACAGATGG
+
CC@FFFFFHHHHHJJIJFIJIJJJJJJGJICFHGJJIIIJJIJJJJJEIJGIIJIJGIJJJJIJJJJJJJJJJJJJJJHHHHHFFFDFFFFEECCEDDDDD
@4JV
AGACAATGAGAGAATTTTTAGAGTTGACAGAACAGAGTCAAAAATTACAGATTCAATTTCAGCAATTACAGGCTAGTGAAACTCTGAGAAACAGCACTCAT
+
CCCFFFFFHHHHHJJJJJJJJJJHHJJJJJIJJJJGJFHIJJJIJJJIJJJJJJJJJJJIJJJJJJJJJJJIJJIG=CEHHEFFFFEEEEEDDCDDDDCDC
@4JW
ACTAAATGAAGCTTTGTCAGCAAAGGAAGAAATTGCTCAAAGATGCCATGAACTGGATATGCAGGTTGCAGCATTGCAGGAAGAGAAAAGTAGTTTGTTGG
+
CCCFFFFFHHHHHJJJJIJJJJIJJJIJJJJJIJJJJJJJIJJIJJJJJJJJJJJIIIIJJIJJJGIJJIJJJIJJHHHHHFFDFEEEEE>CCCDDDDDDD
@4JX
CCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTGAGTTGCTAAGAGAGAAAACCAAATAAGAATGAATGTGTTT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJIJJJJJIIJJJIJ@EGHHHHHHFFFFFFDDEEDDBDDDDDDDDDDDDDEDCDBCD
@4JY
CCTGTCCAGGGGTATGGCACTGGTGCTTATATTACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCC
+
CCCFFFFFHHHHHIJJJJJJJJJFHIJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHHFFFFFFEEEDEEDDDDDDDDDDEDDDDDDDCDD
@4JZ
AGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGC
+
@@@FFFDE?BAFDGHEGGEFIIIIIGHIGDGGII>GEGCHGIFHIIIIIIIB@>EAECACA?DD@@CCCA>CCCCCCCBD@B@>?@CDDD@BD
@4K0
CTTGGACCTTGCGGCGTCCACTCCATCTGACTCCCTGATTTATGACGACGGCCTCTCAGAGGAGGAGACACCGCTGGTGGACTGTAATAATGCCCCCCTCC
+
?@@DDDFFHDHDHGHBHIGIJJJJJJIIGIHHIGJJJIGIIJIJGJIHHFFDBDACCACACB?BBBDBDDDD@BDBB9?BBCDD@CCCDDDDDDCBBBDDD
@4K1
CGACAGGGCTATCAACGACTTGGAGGGGGCATTTCACAGCAGTGACTAGGGGCATCCCTTGAACAGTAGTAGTTGTCTGCTCTTAGAGCCGGGGGTAAAGG
+
0(052-9((((.22).55(--2<2)((0((-.9>):)))()().)8>16)('''((((794((((,(,,((,,(,,((+((+5/(((+(()005&)&((5(
@4K2
GAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACC
+
@@@DFDDBFFHFHJGGGIEHIGHIJIIGGGIIAEGGIFHHCGHGIGHIJIBHHHHFFFFFBCCEDCCCCCDDDDDDDDDDBBDDDDDDCDDCCEDADCBD
@4K3
GCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGC
+
@@@DDDFFFDFHFGIIBHIIIGGIIGHIIIIHIIIGCHGGGDGGDFGGEHIGGGCGIIDHGIFGEEHGHGFDEDBABAE>>CDDCBC@CCD@B?C>@ADD
@4K4
CTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGAGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTAT
+
@<<BDDADFD3ABF@F;1:?BFFD?BD;DB@B;99?F<D6'-5=@=?@D@E9)6==;;?;)..>AB@@BB>5>::@5>BAAAA:??28?B<<<BBBB?@B3
@4K5
GAAATGTTAGAAAAAGAAAAGAATGCTGTGTTAGACAGAATGGCTGAATCACAAGAAGCTGAATTAGAGAGGCTGAGAACACAGCTTCTATTTAGTCACG
+
78=BDDDB??C?FEG?;:AEFBDDDHDCAF9CGC@EFGAB?FGEBDBHI9BDGFD@BFCCF@CHG@GGECCE7CH<?;?DCC;A;>>CC;@A@CC@@C>?
@4K6
CCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCT
+
@@@FFFFFHHHHHJJJIIIJJJJJJJJHGIJIIJJJIJJIIIJJJIIDHHJIJJIIIIJIIJJJJHHHHHHFFFEFDEEEDEDDDDDDDDDDDDDDDDDC
@4K7
CTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACT
+
CCCFFFFFHHHHHIJJJJJJJJJJJJJJJJJJJJJJJJIJGJJJIJIIJJJJIJJJJIJJHHHHHHFFFFFFDDDDDDDDDDDDDCDDDEDEDDDDDDDDD
@4K8
GGGCAACAAAGCTATGAAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTT
+
((-=3=<<(>.):))@):@@@<4)86)9.-=:@?1=:>)<<)<97<<>)097)6=1:>8::77>?>?>>?0=7);1.(93'(,53287'(++6:(3222:
@4K9
CAAGCCTTCAAAAATGAAGTAGGAGTACTCAGGAAAACACGACATGTGAATATCCTACTCTTCATGGGCTATTCCACAAAGCCACAACTGGCTATTGTTAC
+
???D7BDDDD>D:E@<CDE3?<C:33<+?C9EE<CED3??6)?@@DD<49@=BB:8B=@EEC4==@A;ADDCC.)7);?>>(6(5;==>AA?=:>AA5(5>
@4KA
GATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCCCTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGC
+
<@7DBD+==CCFAF?DF@EAFFC?F=C?2:C;)8CD9B?9B<DFE<F;BC>C8CB@)@FAE<E)66@2=>E@BB;?B6@3(6;,5@(->??BB???28?<<
@4KB
GGACAAGTGCAAGCCTATGTCCTATGAGGAGAAGCGGCAGCTCAGCTTGGACATCAACAAGCTCCCCGGCGAGAAGCTGGGCCGCGTGGTGCACATCATCC
+
CCCFFFFDHHHHHJIJJIJIJJJJJJJJIJJJJJJJJIJJJJJJIGIIIJJJJJJJJIJHHHFFFFFDDDDDBBDCCDDDDDDDBDBBD8?CCCDDDDCDD
@4KC
ATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGAT
+
@@@DFFDDFDHHHGGBBGG7EEFBFHGADF@?@FGEGIIIEAEGHIGGIAFHGII;5=CAEHF>C;??=?CC5@>>CC?8,3:ACB?CCDDC<ACCACCCC
@4KD
ATTTTCCTCTGGACCTGGAGCGGCCATTCACTCACAAGAAAACAGGGAATTTTTGGGAAATATGATAAGCCAAAATTTGTGCAGTGTTTAGCATTCTTGGG
+
0(0((2)2=>:4)(.:??(3=2=/(:6;>888).)7)6=<<<<(<?9(..;:>;;?86=(;)838((.(3:((,9;633,,(5557(75:626:2:;:526
@4KE
CTTACAGAAATCTCCAGGACCTCAGCGAGAAAGGAAGTCATCTTCATCCTCAGAAGACAGGAATCGAATGAAAACACTTGGTAGACGGGACTCGAGTGATG
+
CCCFFFFFHHFHHJJJJIJJJJJIIJJIGHIJJJJJJIJJJJJJIJJJJJJJJJJJJJJJJIJJJIHHGGHFFFDFDDECECDDDDDDDDDDDDBB@ADDD
@4KF
CTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTT
+
CCCFFFFFHHHGHJIJJGJIIJJJIHHIJJIJIJJJJJJJJIIJJJIBIIGIJJJJGJIIIHGHHHHFFFFFFDDDDDDDDDDDDDDDACCDDEDDD9<5?
@4KG
CCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCT
+
CCCFFFFFHHHHHJJIJJJJJJJJJGIIJJJIGIJJJGHIIJIIJIJJJJJJJJJJJJJJHHHFFFFDEEEDDDDDDDDDDDDDDD>BDDDDDDDDDCCDD
@4KH
CCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTT
+
@CCFFFFDHFDFHIJIGICEEFCHEHHIJIEGGIJJJIIFGGAFHIIIJIJIIGIJJJJFGHIHHHHHFEF@DCEECC>A@CDCCEDDD@CCDDDDCB?AC
@4KI
CTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTAT
+
C@@FFF?DHGFBFHEEHIIIIIIIGHCFGDFHHIIIIIIII:ACEGHIIIEH=CE>CDDFFCDCDEDDD??C;CCA>A(5>@CCBB?BBBB?@B<:?BCCA
@4KJ
GACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTG
+
@@@FFDDFHHHHHJIGGDGHJJGJJJJJIIHGGHGIIIJFIHGGHGICCFGHIJGEEGHFHHFGFFFDFDACECEC?CDDDDBDBBBBD@CCACBDBBDD?
@4KK
GTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACC
+
81=?A8;3D?+2+<<AA@AA:AFDC;9C:EE*CDD*:<D>*?99*9?)?D<<6<A).)8@@CE;AD=;ACADDDA?A6(;36>555;A??>>:>><9?><<
@4KL
CTCCTTCGGAGTTGCACAAGGTCCACGGATCCAGAAACAAGCCCACCAGCTTGTGGAACCCAACGTACGGCTCCTGGTTTACAGAGAAACCCACCAAAA
+
=;@DDDDDDD@CCEDH@FA::ACFAE:?FDHCGCCG@CHIIIBAHHII;C7.).=;;7?;9;9;;?@A@@B6383>?,4?9@>>@ACCCC?8@?B8ABB
@4KM
GGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCT
+
+11=D?BD=CD8D<B:CBEF3CAACF;BDFF>EE?EEDEEIDIDDIDDDIB?CACEEADE<A3AAD4@CCC?DC@DA@D;>;@;>?35>AAA>:>A:A??
@4KN
AGATTGAGCCAGCGCCCATGAAGAGCAAGCCCCCTCCCACGTAAGAGTCGGAGGAAGAGGACAAGGGCAAACCTATGACCTATGAGGAGAAGCGGCAGCTC
+
(--((:;4))@.@;3(2?))=@@8>7)=.(-036=61=?95=>((<)..5:=5=((900((,9;5((,7;(86(:(((++:6;(:62+(((((555&8(+(
@4KO
AGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTC
+
+:=DB>DDHHFHG@GEIG9FHIIIII@GC?FDCAFGIIIIGBEHDGIHICGIEHIGEFG:D==@CCECE5?BCE@>@>>?C;@BB@B8;B8?<<:AC>(:A
@4KP
TATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTAC
+
CCCFFFDFGHHFHGJJIJJJJJJIIJJJJGGHIIJGIIIJJJFIIJJJIDIJJGGIGIHIIJIG@GHGGGHEEDDFFFEECCDDDDDCDDCDDDDEDDDDD
@4KQ
AGATGACCCCCAATTGAAAAGAGAAATAAGGTTAATGAAAAACAGAGAAGCTGCTCGAGAATGTCGCAGAAAGAAGAAAGAATATGTGAAATGCCTGGAA
+
@<@FFFEDHBDFDEGGIGEEGCFCDEAHIIE?FBFGHGIIIIHGEHDFHGHB=CDGHHGHGII77A6?9>>;6A?C?CCCC?:>@C;BADC@CCCCCBBC
@4KR
GACATCTCCTGTGACTCTCACCTCTCAGACAACTAAGACAGATGACCCCCAATTGAAAAGAGAAATAAGGTTAATGAAAAACAGAGAAGCTGCTCGAGAAT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJIJIJJJJJJJIJJJJJJJJIJJJJJJJJJJJJGIIJJJJJHHCHHHFFFFFFEDDEDDDDDDDDDDDDDDDDD
@4KS
AAGCCCTTTTCTCCATGGCCTTTCCAGATAATCAGCGTCCACTGCTGAAGACAGACATGGAACGTCACATCAACGAGGAGGACACAGTGCCTCTTTCTCAC
+
CCCFFFFFHGHHGJJJJJJJJJJJIHIGIIJJJJHIJGJIIJJIJIJJJIJIJJJJJIJIJGIIJIIHHHHHHFFFDDDDDDDDDDDCCDDCDDDDDDDED
@4KT
GTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGC
+
@@@FFDF?FHHFHIGGCEHGGHIIEHIIICFIHIIGIIIBGFCGIIIFHHIIG=CFGEEHHGGEHEH;CEDCBBCECCCECCDDDDDDDDDCDDB?CDD
@4KU
GGCATGGTGATGTGGCAGTGAAAATGTTGAATGTGACAGCACCTACACCTCAGCAGTTACAAGCCTTCAAAAATGAAGTAGGAGTACTCAGGAAAACACG
+
CCCFFFFDHHHHHIJIJJEGIJJJJJJJJJJJJGIJJJJJJIJJJJFIJJJJJIGIHIJJJJIIJJIJIIJJJHHHHHEHFFDFEEEEEEEDDDDDDDDD
@4KV
GCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCC
+
CCCFFFFFGHHHHJJJIJJJJJJIJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJHHFGHFFFFFFDEEEEEDDDCCDDDDDDDDDDD>BDDDDDDBDDDD
@4KW
CAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATG
+
@@@FFADDDDDHDHIBHBBHHE@FHGD9C<C<DCGHGII@FGFFGGHIAH9FGHCEG@FGGCGGC>@CEHEDBADB??BC>3@CACDBAC@CBC:>4>CDC
@4KX
CACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGAT
+
@@@DBDDDDDAHD?EG:FHEIIEEHGIIIGIDHIGE??FAGCFHG?DHGDHGIGIIGBIHGAHFFCBBB>ACCC?BCB@ACCDDCCCCBBBBBB?@CCCC@
@4KY
AGGGAGACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCT
+
?;+4B8822<D@@F;EBG811?:?8:?08@/B87C=85;==7.=D@AF<9;;5>'3'5>5,>A>B55:@5(>4+(2+@3((4&5&))(+()22<93>B3(+
@4KZ
GTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACA
+
@@@DFFFDHHHHHJJJJJGIJJJJJJJDGIIIIJJJJJJJIJJJJIJIIIHIJJIJIJJJIJIIJJEEHHHGFFFFDEDDDDDDBBDBDDDDDDDDCDD
@4L0
CCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTC
+
CCCFFFFFHHHGHIJIJJJJJJGIJJJJJJJJIJJJJJJJIJJJJJHIGDGIJJJIIJHHFFHHHFFFFFFEEEEEDDDDDDDDDDDDDDDDDDDDDDDDD
@4L1
CTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAAC
+
CCCFFFFFHFHGHIJGIGDGIJIIIJIJGIGJJFGHGHJJJJIGJJIIJJIIJJIJGGIHHHFD>@DDDDDBDDDDB@DDDDDCCCCDDDDCDCBDDCCDC
@4L2
GCCAAGGGAAGGACGTCCTATGTACCAACGCCAGATGTCTGAGCCAAACATCCCCTTCCCACCACAAGGCTTTAAGCAGGAGTACCGCGACCCAGTGTATG
+
CCCFFFFFHHHHHJJIJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJIHHHEFFFFDDEDDDDDDDDDDDDDDCCDDDDDDDDDDDDDDEEE
@4L3
CTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGC
+
CCCFFFFFHHHGHJJGIJIJJJJJJIJJJIJJJIJJJJJJJIGIJJIGIIJIJIHGHGGHJIJIJHHHHFFFDFECEEEEEEDDDDBDDDDDDDDDDDDD
@4L4
GGAATTTTTGGGAAATATGAAAAGCCAAAATTTGTGCAGTGTTTAGCATTCTTGGGGAATGGAGATGTTCTTACTGGAGACTCAGGTGGAGTCATGCTTAT
+
@C@FFDFFHHHHFJJJJJJJIJJIGIIGHIJIJJJIJJJFGGIGJJJJJJIJIJIJIGJIJIIHHIJJJEHHHHHHEFFFCEEEEC@CBDD@CDEACDDCC
@4L5
CAACAAATGAAGTTGTTTTGGCTGTGGAGTTTCACCCAACAGATGCAAATACCATAATTACATGCGGTAAATCTCATATTTTCTTCTGGACCTGGAGCGGC
+
@@@DDD>DF?4C?BGHGBEDGGGECF@9F:EEGFGHEIIIIIGIGHGHI@FGHGII@FDHGIIICHI:EEEDFFDFFDDEDEC@C@CCCCBCCCA?BCBB9
@4L6
CCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGAC
+
@CCFFFFFHGHHHJJJJGHIIIJJIGJIJJJJJJJJJJJJJJIJJJIEHJFHIIJJIGGIIGIJJHHHHHFFFFFEEEDDDDDDDDBCDCDDEDEEEDDD
@4L7
GGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTAC
+
<;;DBA+2<3<:A2?<+2A3A:<AFDE>BE9;?B<DDC@?@7B@=C78A73.==@?=(=)7?DA@@?85;=9>A9:((,>AA;>AADD>:::08<>>>4:A
@4L8
GGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGC
+
CCCFFFFFHHHHHJJJHIJHIJHIJJJJIJJJJJIJJIJJJJJJJJJHHHHFFFFFFFEEEEEEDDDDDDDDDDDDDDDDDDDDDDDDDCCDEDDDDDDDD
@4L9
CAGGTGGTCGTACAAACTGCATCAGGAGATATGCAAACATATCAGATCCGAACTACACCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATGACATCTCC
+
??@D=B;A?D<CAFEFGDEHIG@FGFGGI<FB@AGHIEHGI<FGIHEGGGGIIDGIIIIIGHIIEEEEFHB>CEEECC:AAB;@@;;?<?AACCCCA:>5:
@4LA
GACAGTCCGACTCATCTAGAGATGATGGAAAGTGAGTTGGCTGGGAAGCAGCATGAGATTGAAGAGCTAAACAGAGAGCTGGAAGAAATGAGGGTTACCT
+
?<@DDDDEBFHFHBHIIIIIIIGGIGBFGHIICFEHHIIIIGHIIIGGIGIIIIGCGIIIGA@G@EEEHHFFF@DDDA=@AC<CCBACACCCCC8<ACCC
@4LB
CCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGT
+
@@?DDBBDBDB?DEBG@?@F:::DD?G;6D@BFHCG@=FC>GHADHGCDDDCA77?77;;?;;;;@>>@;55=5;@ACCB<51,+::92?0393@:ABBBC
@4LC
CCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTC
+
@CCFFFFFHHHHHIID<EGIGG<FHIDCEE@HIDEABHEG?DDHGGICDFEHBB=CDHGGHHEHHHCCD?@@CCEACA@AACCC?5>@CCACCCECBCCCC
@4LD
CTCCAACTTTGCTTACCACTTGGCCTCTAAACTTAGCCTCTCACCAAGGGAGCATCCCCTCAGTCCTCACCATGCCTCGGGAGGTCAGGGCAGCCAGAGA
+
+:=++22+@>@+<+227<+=+<7A7+<++<77=@<7A<:AB>=AB7;=8<2>:=>AABABA>;=A).=35A>)).).)'33''',5;=955()289<=7(
@4LE
CTCGCGCAGGATACGGAACTGAGAAGACGCCTACGGCTCAAAGGGAACTTGGGTAAATATGGAACACATTTAACGTGGCAATAGATTTTAAGTGTGCAAA
+
0((2((((-(:))22(((()1)))))<)7=((()-7''-8))))-7((.).)(,..=((-(--3(,73::((((,(75&+((+(+62(++(+(((++(((
@4LF
GAAGGATGCTTCAGCTCATCTTAGGCTGTGCTGTGAACTGTGAACAGAAGCAAGAGTACATCAAAGCCATTATGATGATGGAGGAATCTGTTCAACATGTT
+
+112<AAAA+22<2?+<A<+33<3<++22@7<A::A41:?*?BB7A=**=0==>=A99?4/.)98A).8>>77=ABBB>>A7A;@()6(66>5;>955;5;
@4LG
CATGCCCACCAGCAGAAGGGGAACTTTGTCCCTCCCCATCCATCCTCCATGCCTGTCACTTCCTCCAGCTTCTTTGGAGCCGCATCACACTACTGGACCTC
+
=;+?1<<7ACCBBBCB7=<)@<A5**11*:AA=;;=:0>=A=/=57===A)>BBA/8>47.=).=AA>))7>;;>;3(.6;=',333(:(++8+:(+8;(8
@4LH
CTTGAAGACCTTGTTGAAGAATTGAGCTTTTCAAGGGAACAGATTCAGAGAGCTAGACAGACAATAGCTGAACAAGAAAGTAAACTTAATGAAGCACATA
+
CCCFFFFFHHHHHIJJJJJJJJJJJJJJJJJIJJJIJJJIJJJJJJJJJIJJJJJJJIJJJJJJIJJJJJJJJHHHHHFF7@DFEEEEEEDDDDDDDDDD
@4LI
CTACACCTTCAGCTACTTCTCTGCCACAAACTGCGGTGATGACATCTCCTGTGACTCTCACCTCTCAGACAACTAAGACAGATGACCCCCAATTGAAA
+
???DD:DB=CDC?EAEIE>>EE<E3CBFEF@@E*::C?DD9BDBE@DDDADBB<B48B@CCDC@7=@)7=;A=?A@);@?;;A>@;>>>?=?9>A(::
@4LJ
CTACTGTAGAGCCCACACCTGGGAAAGGACCTAAAGGTGTATATCAAATCAGCAAACAAATCAAAGCTCATGATGGCAGTGTGTTCACACTTTGTCAGATG
+
@@@DFDBDHDDHGHDHAHFGGGIJJIDGEFFDFCEGEGHFHIDBGHHDAGCBEGDHCGD=@GHCDEH7=CEEAEHDFFF;>AC>ACDC@CCCCCD:>CCCD
@4LK
CTGAAGACAGACATGGAACGTCACATCAACGAGGAGGACACAGTGCCTCTTTCTCACTTTGATGAGAGCATGGCCTACATGCCGGAAGGGGGCTGCTGCA
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHIJJIJJJJJIJIJJJJJIJHHHHHFFFFFEEEEEDDDDDDDDDDDDDDDDDDDDDD
@4LL
ACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGC
+
CCCFFFFFHHHHHJJJJJIJJJJGJJIJJJJJJJIJJJJJJJJJIJIIJJJJJIIJJIJJIIJIJIIGEHHHFFFFDEDEDBDDDDDDDDDDDDCDDDDD
@4LM
CAGTTATTCAGAAATTTTTTCTTAAATAGCATTTATAAGTCCAGAGATGAAGCAAACAACAGTGGAGTCATAAATGAAAGCTTTGAAGGTGAAGATGGCG
+
@;?BDDDD:DBHHGIHIGIIIIII<<HGHHGGGGBGEFGDCFHHGCHIICHGIGGI8BGCEBFHE>CAEGEEGGFECCAE;BDEDE;AC;ACCCACCC?B
@4LN
CCCAAGAACTGCCCTGGGCCTGTATACCGGATAATGACTCAGTGCTGGCAACATCAGCCTGAAGACAGGCCCAACTTTGCCATCATTTTGGAGAGGATTG
+
@@@FFFFFFDDFHIGJEGGIIIHHIJIJIIJIJJJJGJIJIIHIJGJIIJJGIJJGGIIJIGIGHGHHEEFFDDDEDDDDDDDDCDDFEDDCC:@B?CCD
@4LO
CAAGGATTTCGTGGTGATGGAGGATCAACCACAGGTTTGTCTGCTACCCCCCCTGCCTCATTACCTGGCTCACTAACTAACGTGAAAGCCTTACAGAAATC
+
@CCFFDFFHHGHDIGGHGIIJIJJJJJJJJJJJJIGIJJGGIIJIJJJJJJJHFEFFCEDEEEDDCDBDCDDDDDDDDDDCDABDDDDDDDDDDDDCDDDD
@4LP
CCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAG
+
CCCFFFFFHHHHHJJJIJIJJJJJJJJJJJJJJJIIJJJJJJJIJJJJJJJIJJIJIJJJJIJJHHFGHHFFFFFFCEEEEDDDDDDDDDEEEDDEDED
@4LQ
AAAGGAAAGAGGAAGTGGAAGAGAATAAAAAAAGCAAAGCCAAGGAACCTCCTCCTAAAAAGACGAAGAAAAATAATAGCAGCAACAGCAATGTGAGCA
+
CCCFFDFFHFHGHIIEFIEGGGIFHHHIJJJJJJJJJJJJJJJJJJJJJJIIJIIHHHHHFFBDDDBBDDDDDDDDEEDDDDDDDDDDDDDCDADDDDD
@4LR
GCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGC
+
@C@FFDA?CFHHFGFIGBHIIEDFHGGIIIIIGGGGIEAGAHGHHHIEGGGGEGEEFEHEAACHCHEEDCDDEEA?CCCC9;A>CD@@CEDDDDC?BDCCC
@4LS
TGATTATCGAATACGTTGTGAAGAGTTAGAAAAGGAGATCTCTGAACTTCGGCAACAGAATGATGAACTGACCACTTTGGCAGATGAAGCTCAGTCTCTG
+
CCCFFFFFHHHHHJIIJEGIIJIGHEHIJJJIIIJJJJIJJJJJJJJJJJJJJIJJJJJJJJIIIIHHHHGHFFFFEEEEEEDDDDDDDDDDDDDDDDDD
@4LT
CCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTAT
+
CCCFFFFFHHHHHIJJJJJJJJJJIJGIJIJIJIIJJJJJJJJJJJJJJJJHHHFFFFFEEEDEDDDDDDDDDDDDDDDDDDDDDDEDDDDDBDDDDDDDD
@4LU
CAAGAAAGTAAACTTAATGAAGCACATAAGTCCCTTAGTACAGTGGAAGATTTGAAAGCTGAGATTGTTTCTGCATCTGAATCCAGAAAGGAACTAGAATT
+
CCCFDFFFFFHHHJJJJJIIJJIJJJJJJJJIJJJJJJJJJJJJJJJJJHIJJJJJJJJJJJJJJJJJIIGIJJJIJJIJJGFGHHHFFFDEEA@CEDDCD
@4LV
AATAAAGACAACAAATGAAGTTGTTTTGGCTGTGGAGTTTCACCCAACAGATGCAAATACCATAATTACATGCGGTAAATCTCATATTTTCTTCTGGACCT
+
CCCFFFFFHHHHHJJJJIJIHHIIIJJJIBHIHIIIIHIJJJJJJJJIJJJJJIJIJEGCGIGIJJJJFGFHEHFFDDEFDEDDDCDDFEDDDDDDDCBDD
@4LW
GTCATGTGATACTCAAGTAAGCTCTTTATTAGATGGAGTTGTGACTATGACAAGCAGGGGTGCTGAAGGATCAGTTTCTAAAGTAAATAAAAGTTTTGGTG
+
:11A1?=:ADD??:2A<2,3CEB?A<AA@CCF?ADF@C?EE9:?DFBDEI9?0???BDDD'5A=A4.==6=?DD@@A@A>;6@6>@@B>>>>>-5>A=85<
@4LX
CCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACT
+
@@@DBDDDFFHHFG4C?FH?HGEHGECDGFH?GGEHGIDD3BG?9DFFGECHGCHEHGEGG;CCHDEHFHFHEF?>=D;;;AACA>?;;<299@?A?A@CC
@4LY
GCATCAGGAGATATGCAAACATATCAGATCCGAACTACACCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATGACATCTCCTGTGACTCTCACCTCTC
+
@@@DFFF<DHDFHEGFC>EHEFEHHIGIIFIIICGGFGGHGIGIEGHIIIIIFIGEHIGGAGIGHCH@CE.;EEEFFCEFDEECDECCCC@>CCDDDBDC
@4LZ
CCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGATATACTTCGTTGG
+
CCCFFFFFHGHHHIJJJJIIJJJJJGIJIHIJJJJJJJJJJJJJJJJIJJJIJJGGIJJIJJJIJHHHGGFFFFFEEEDDDDDDDDBCCDEEDDDDDCCDD
@4M0
GTGCCTAGCTGCCACTCCATTTATATGAGGCAAGAAGGCTTCCTGGCTCATCCCAGCAGAACAGAAGGCTGTATGTTTGAAAAGGGCCCCAGGCAGTTTT
+
CCCFFFFFGHHHHJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJHJJJJJJIJJJJIJJHHHHHHFFFFFFEEEDDDDDDDDDDDDCDED
@4M1
CCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGC
+
CCCFFFFFHHHHHJJJJJJJJJJHIJJJJJJJIJJJJJJJIJJJJJJJJJJJJJJJIJJJJJJJHHHHHHFFFFFDDDDDDDDDDDDDDDDDDDDDDDDDD
@4M2
CCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTTATGGG
+
CCCFFFFFHHGHGIJIJJIHIIJJJJJJJJJJJJJIJJIJJJJJJIJJJJIIIGGJIIEHJHHHHHHFFDDDDDDDDDDDBDCCCDDDDDD399BDDDDDD
@4M3
CTTTCTGCGACATTCTCGAGCAGCTTCTCTGTTTTTCATTAACCTTATTTCTCTTTTCAATTGGGGGTCATCTGTCTTAGTTGTCTGAGAGGTGAG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJIJJHIJJJJJJJJJJJJJJJJJJIJIJJJJIJJJJJJJHABEEDDDEDDDEDDDCCCDDDDDDDCBDD
@4M4
CAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAAC
+
CCCFFFFFHHHHHJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJHHHHHFFFFFFEEEEEEEDDDDBDDDDDDDDDDDDDD
@4M5
ATTCAATTTCAGCAATTACAGGCTAGTGAAACTCTGAGAAACAGCACTCATAGTAGCACAGCTGCAGACTTACTACAAGC
+
CCCFFFFFHGGHHJ@GHBFHIIJJIIHGIIJIJJIJIJ@BGGIIGGEEEGEII@HIGHEGHBGH>FGGCFHIJI@EH=CE
@4M6
CAATTACCATGTTCATTCCTTCCGATGTTGACAACTATGATGACATCAGAACGGAACTGCCTCCTGAGAAGCTCAAACTGGAGTGGGCATATGGTTATCG
+
@@@ADBBDDAFDBFFBB4?4CB@E?1CA@DD>BFFAD9@C>ED@D>@?DBE?FECE@>FB=;AF@CAE@@C7;;?@?3;BB>@(;??;=3;(;@((5((5
@4M7
AAAAAGTAGAAAACTCAAATAAAGAAGAAATACAGGAAAAGGAGACAATCATTGAAGAATTAAACACAAAAATAATAGAAGAAGAAAAGAAAACTCTTG
+
@@CFDFDEGFFHHJJGGHIIJIJJJJIIJJJIJJJJGIIJJJGIJJJJJJJJJJJJJJJJJJJJJJJJJIJHHHHHFFFFFFDEEDEDDDDDDDDDDDC
@4M8
CTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGT
+
@@@DDDF<DFHHAHGHGIGGGII9EEGHIIGGHIBG?FGEHIIG9@DEBFCFEEGB@FACCCGHIIBC?CC>>B@@B?@@>>@=AA:@CCC@AABCC89<4
@4M9
TGGGTGTGGAGAGGAGAGGGTCTGGGAAGGTTATAAACCAGGTATCTCTACATCAGGATGGCCATCTAGGAGGCGCTGGGCCTCCTGGGCACTGCCTGGTG
+
@CCFDDDDHFHFHIIIJJJJFHHIIJJJJJEHIJJJJJJJJJ9BHIIJHIIJJFIJJJEIIIHHHHHFFFFFDDDDDDDDDDDDDDDDDDCDCDDDDDD4?
@4MA
CGTCCTCAGAGTCGGAGAGCTCCAGTGAGTCCAGCTCCTCTGACAGCGAAGACTCCGAAACAGCACCATCATCACCACCATCAGCAGATGCAGCAGGC
+
@?;DD?DDFA?<A@@FE6;FGHGAF@BD>FGG@FDB@E>FDE9FBBBEEBAAD=DDAEFDEECCAA@?CCCF:@ACCBBB:?C:A:?C@CCCCC???>
@4MB
CTATGTCCTATGAGGAGAAGCGGCAGCTCAGCTTGGACATCAACAAGCTCCCCGGCGAGAAGCTGGGCCGCGTGGTGCACATCATCCAGTCACGGGAGCCC
+
CCCFFFFFHHHHHJIJDHEGIGIJJJJGIIIJJJJIHIIGIGIIJJJJGHIJJIFEDDBDDDDDDDDBDDBD;BD<@C@ACDDDDDDDDDDDCDDD@>@BD
@4MC
NATAATCAGCGTCCACTGCTGAAGACAGACATGGAACGTCACATCAACGAGGAGGACACAGTGCCTCTTTCTCACTTTGATGAGAGCATGGCCTACATGCC
+
#1=DDFFFHHHHHGIIIDEEFEIIIIIIGGGGFEIGGIIGBGHIDGIEHIIIDHEHGHFGEHFFFFCCCE@ECCAACDD>ACEC@@BC@>BBCDCDCACDD
@4MD
CGAGGACGGGCTGCATAGGGAAGGGAAGCCCATCAACCTCTCTCATCGGGAAGACCTGGCTTACATGAACCACATCATGGTCTCTGTCTCCCCGCCTGA
+
CCCFFFFFHHHHHJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHFFFFFEEEEDDDDEDDDDDDDDDDDDDDCDDDDDDDDDDDDDDDDDD
@4ME
CCGCCTGATGCTGCAATGCTGGAAGCAGGAGCCGGACAAAAGGCCGGTGTTTGCGGACATCAGCAAAGACCTGGAGAAGATGGTGGTTAAGAGGAGAGACT
+
?;1:4AD>DB+CC<?E>@3AB<CF>FDFEDEADAA0@DD>8?;(85AAA45??3?@6;8;AA>A:9>:59+:<>2+(23(4:((48084>>(:<++(2<94
@4MF
GTCCCATCAGTTTGAACAGTTGTCTGGATCCATTTTGTGGATGGCACCAGAAGTCATCAGAATGCAAGATAAAAATCCATACAGCTTTCAGTCAGATGTAT
+
CCCFFFFFHHHHHJJJJJJJJJIJJJJJJJJJIJJJJHIJJJIJJIJJJJJJJJJJJIJJJJIJJJJIIIIJJJJJHHHHHFFFFFFEEEEEEEDDDDDEE
@4MG
GGGGCCCTTGCCTCAGTGGGGCTGGGGCTGGCAAGGTCATTGTCAAAGTCAAGACAGAAGGGGGGTCAGCTGAGCCCTCTCAAACTCAGAACTTTATCCTT
+
@;@DDD?DHFHFHHG>CE;BGGGHGAGGGGIICGIB?B@FGI@GHIIIHIGIIFIIGEHHFEEC758<<@CCC?CCBCBC?ACC>@CCCCCCCCC@CCCDC
@4MH
CTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGC
+
@CCFDFFFHHHFHIEIFHIJJJJJIJIJGJJIGGJJIIGIJJIGJJJIIIEIJJJICHGHHGEHGHHHCF@DBEDCCCECDEDDDDDDDDCDDDDDDCDD
@4MI
CAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATAT
+
@??DDDB?A<:C?EHIIAEBHGGHFHG9FFHEAHGGBAGGG3?BBGCGGIIE@.=8BFGHF@EGEHFHEEE<@B@AC;;;ABB95?CCCCAC(:>CCDC
@4MJ
CCCCACAGTCCATGTTCAGAAATCGGCTCTGCCTGCAGTCAAGAACAGCCCTTTAAATTCAGCTATGGAGAAAAGTGCCTGTACAATGTCAGTGCCTATG
+
@@@FFFFFHHFFFIEHGIJJJJIJJJJGGGEHIIJJIJIJIJJGGIIJIJJIIJJJJJJJJJIIJIJJGHEEHFF@DEDEECEEFEDDDEED>CCDDDDC
@4MK
CCCACTGCATCATGCATCTCCAAACTCAACTCATACACCGAAACCTGACCGGGCCTTCCCAGCTCACCTCCCTCCATCGCAGTCCATACCAGATAGCAGCT
+
CCCFFFFFHGFHHJJGIJJJJJJIJJJJIJJJIJJGCHIIGJGIIJJIEGGGEIHHHHHFDDFFECEEDDDDDDBDDD@B@=8?CA>CCDCCBCCDCCCBC
@4ML
GGAAGATTTGAAAGCTGAGATTGTTTCTGCATCTGAATCCAGAAAGGAACTAGAATTAAAACATGAAGCAGAAGTTACAAATTACAAGATAAAACTTGAA
+
@@<DDDDFFDDHHJJJIGHHGEIFGHJGIIIJGHIGBFFHIJJGGHHEEHIHI>FGIIJGIIFIIECFHHGIIIEHGHHGHHGEFFFFFDEEDECDDDDD
@4MM
GACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTG
+
CCCFFFFFHHHHHJJJJIJJJJJJJIIIJJJIJJJJJJIIJJJJJIJIJJJJJJIIIJJJJFFFDDDEDDDCDDBDDDDDDDDDDDDD9@CDDDDCCDD@C
@4MN
GACCCAGTGTATGAACACAACACCATGGTTGGCAGTGCGGCCAGCCAAAGCTTTCCCCCTCCTCTGATGATTAAACAGGAACCCAGAGATTTTGCATATG
+
@CCFFFFFHHHHHJJJIJJIIJIIJIJIEHIJJJIHGIJJIIJIIIIJJIIJJJIHHHHDFFCEEEEEDDEEDDDDDDDDDDDBDD?BCDDDDDDDEDDE
@4MO
CTTCAGCATATTCTGAAGCAGAGGAAACCTCGGATTCTTTTTTCACCATTCTTCCACCCTGGAAACTCTATACACACACAGCCGGAGGTCATACTGCATC
+
@@<D?DD?B?FHHCGEHGGHIGGEHHEEHIHIIGGIIIIIEIIIEGCDG@F>BGHGGIIIIGHI>=ACEEDEEEDE?AA@?AABBBBB8<@ACCACCCCC
@4MP
TGGACAGTTACCTTATTCAAACATCAACAACAGGGACCAGATAATTTTTATGGTGGGACGAGGATACCTGTCTCCAGATCTCAGTAAGGTACGGAGTAACT
+
CCCFFFFDHFHHHJIJJJJJIJIJJJJJJJJJJJJIIJJJJJJJIJJJIJJJJFGHIHIIIHHEEFFFFEEEDEEDCDDDDDDDCDDDD:ACDDBB?CCCC
@4MQ
CTCGATAAGATTTGCCTGAACCACGGGCTGTACCTTGATGCGCGGGATGTTATATCAAACGTTATTCCGGAGAACAAGAGCATGTAAGAGTGCCAGGAACC
+
00-((2(()9))))).2.4<).(((-3=?6()0>)7).7)98(';=/,()).((.:=((('7((,77,(',&&+68(+6(2((+++((+(((+(5:88<88
@4MR
GCTTCCTGGCTCATCCCAGCAGAACAGAAGGCTGTATGTTTGAAAAGGGCCCCAGGCAGTTTTATGATGACACCTGTGTTGTCCCAGAAAAATTCGATGG
+
CCCFFDFFHFFFHJJJJJEEGHHIIHEHIDHIJIGGGHIIIGDGGGGEHIIIIGGHDHGHHJJGHFEHGHFFDFDEEEEEDCCCDC@ACDDDDDDBEEED
@4MS
CTCTCACCTCTCAGACAACTAAGACAGATGACCCCCAATTGAAAAGAGAAATAAGGTTAATGAAAAACAGAGAAGCTGCTCGAGAATGTCGCAGAAAGA
+
??+:1+=A?>DD>EBEEI<EA+:<F@EEE99?EE=DDD?BA<D>BBDD<D@8=8=B=C@@@CEIIAA8A3?>3?>A>>AAA@????A>359?80>AAAA
@4MT
CTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTT
+
8?@?ABDDFFH?DBGI@GGF3F>EABDD>FEHIIEGCEGIGBGHB3BFC>BFC?AB848;DA=C?CEDCD;;BAC@?=;?<@?BB=?B:@CCCCC@BA<5?
@4MU
CACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAAT
+
@@@DDDDDFFFFBEGBGIE+AFGE4A9?CB@GGEGIIEEEBFFFGDEFCEEAEFIFDEFFFF><B?@@B>>@BBBB@@BBB9>AABBBAB3@>4@BBBAB:
@4MV
GCTCCAGAAAGTTTGATGGATGGAATCTTCACTACTCAATCTGATGTATGGTCTTTTGGAATTCTGATTTGGGAGATTTTAACTCTTGGTCATCAGCCTT
+
<=<AAA+727?2<7A?AB9@BB=9ABCBBB474:AABABBBAA<<<0??4?BABBA?>0>BBABAA=>BBA9A=;A>AAA>A;>;>@>@(.>(.;(;55;
@4MW
AAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTAC
+
CCCFFFFFHGHHHIHIIJJIJHJJJJIJJJJJJIJJIJJJIJJJJAFHIJJJJHHHHFFFFDEDEDDDDDDDDDDDCDCCDCDDDDDDDDEDDDDDDDACD
@4MX
CCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTAT
+
C@CFFFFDHHHHFJIIJJJGGIIJJEGHHGJJJJDHHIJJJJJJGJGIGIIHGEDDFFFDEEEEDDDEACDDDBDDDDDDBBDDDDEDDDDDBDDDCDDDC
@4MY
GGCAAAGCCAAGCTTGCCCAGTTTCGACAAAGAAAAGCTCAGGCGGATGGGCAGAGTCCTTCCAAGAAGCAGAAAAAAAAGAGAAAAACGTCAAGCAGTA
+
:8=DDD>DHFD?FHEHIIIIIACCFGC8?GIC;DGIA;DFG@*9DG<AA;EHHBEE;@;>C>A;;;=?A?><5?CCBB@@BB?<CCCBBB<8<B@:?CAC
@4MZ
CCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGC
+
CC@FFDFFHHHHHJJJIJJJJGGGHIGIJJIIJJJGIIJJJJBGIJIJJIJIGJIIIJGIEHIIJJIIHHHHHFFFFFFEEDEEDDDCDDDCDDCDDDCCD
@4N0
ATTTGGTGTTGATGATTCTTATTCTGAACAAGGAGCACAAGACAGTCCGACTCATCTAGAGATGATGGAAAGTGAGTTGGCTGGGAAGCAGCATGAGATTG
+
CCCFFFBDFHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJGIIGIIJHHHHACFFFFFEEEDDDDDDDDDDDDDDDDDDD
@4N1
TGGAAACTCTATACACACACAGCCGGAGGTCATACTGCATCAGAACCATGAAGAAGATAACTGTGTCCAGAGGACCCCCAGGCCATCCGTGGATAATGTGC
+
?@@D?DDDHHFHFGGIIHHG?3CFABG6F):DFHGGIEDFFHEHIDFG@C@G@CH>DDCGH?A7?ACB@;@BCBCCBBBB?BBBB33<98?B7ADCCC>>A
@4N2
ATGCACAGACCACCCAGCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTAT
+
@@@FDFFDFHGGDGIIGIGCHIIJJEIIIIIJJJIGGEEGIJGGGIIGGGGIEGIFIJJJJHEEEHEEFDFFFBCEECCBBBBBDDDD@C?CCCCDDDCD@
@4N3
CCTCCATCCTACCCCCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCT
+
CCCFFFFFHHHHHJJJJJJJJJJIJJJJIJJJJJJJJJJJJJJJJJJJIJJJJJJHHHHHFFFFFFEEEEEEEDBDDDDDDDDDDDDDDDDDDBDDDDDD
@4N4
TTTTCTTAGACTCCATTAAGTCCAAATCCAAAGACTCTGTGTGGGAAAAAGAAATAGAAATACTTATAGAGGAAAATGAGGACCTCAAACAACAATGTATT
+
CCCFFFFFHHHHGJJJJJJJJJJJJJJJJJJJJIJJJJJIIHIIJJJJJJJJJJJJIJJJIJJJJJIJJJJJJJHHHHGFFFFFEEEEEDDDDDDDDADDF
@4N5
GATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGC
+
CCCFFFFFHHHHHJJJHIJJJJJJJJJJJJJJJJJJJJJJJJJJHIJJJJJJJJJJHHFFFFDDDEDDDDDDDDDDDEDDDDDDDDDDDDDCDDDDEDDD
@4N6
GCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGT
+
CCCFFFFFHHHHHJJJJJJJJJJJJHIHJIIJJIJIIJJJJJJJJJJJJEHIJJJJIJIJJHHIJIJIGHHFFDEDEEDCDDDDDDDDDDDDDDDDDDDDC
@4N7
CCTATGGGCATCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAAC
+
;;(5()):7;)2..)2:3193>>7)):;>31@=>??<?>????376))-86.6;7;?=?>909=;19886;==>>;3;;6;=0;7=5<;/(20:)56<<=:
@4N8
CTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACC
+
CCCFDFFFHHHHHJJJJJJJJJJJJJJJHHIJJJJJIJJJJJJJJIIJJJIJJEHHHHFFFDFE@CEEEDDDDEEDDDDDDDDDDDDDDDDDDDDDDDDDD
@4N9
GTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTAC
+
?@@FDEFFHGFDBDAGGBDGEBFC>FGBFFGIIGIIIIGGHE>FHCBEHCBCGCEGHECHGE=ACCEEF7?C;AAA@CC;;;>BBA@<ACB?ABACCCDDC
@4NA
GCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJIIJJIJJJJIJHIIJIJIJJIJJJHHHHHHHFFFFFEDEEEEEDDDDDDDDDDDDDDDDDD
@4NB
CAAGCCTTCAAAAATGAAGTAGGAGTACTCAGGAAAACACGACATGTGAATATCCTACTCTTCATGGGCTATTCCACAAAGCCACAACTGGCTATTGTTAC
+
CCCFFFFFHHHHHJJJJJJHIJJJJIIJJIJJJIJIJJJJJIJJJJHIJJJJJJIJJJJJJJJJJJJJJHHHHHHFDFFFEEEEDDDDDDDDDDDDDEDDD
@4NC
ATTTGATAACTAAGCAGAATCAATTAATTTTGGAAATTTCAAAGCTAAAAGATTTACAGCAGTCTCTTGTAAATTCAAAGTCAGAAGAAATGACTCTTCA
+
=;?DDDBDD??B??FEGBCC:ADHHIGHHE>FECGDHCC?CF?FCBGBFHB?FHIE>F>AGHII<8BGGGGIEEH@CC>7C=====EEE@EECCC>;@CD
@4ND
CTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCC
+
C@CFFFFFGHGDHJIJIJIGGIIJIJJIIGIJGGIJGGGEGIJIFBGIIGIHFHG=?DDFFFECEEEDEDDDDDDCDDDDCCCCDDDDDDDDDDDDBDDDD
@4NE
GACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGT
+
CCCFFFFFFGHHGIJIIJJJIJJJJIIJJJJIIIFHGJIJIJJJEGIIGGGIJIJJJHABDCDDCD?BDDDDDDDDDDCDDDDDDDACBDC>CCCDDDDDE
@4NF
ATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATG
+
@<@DD8BDFBBDHHIICHIBHH@FE?F@EGGGIIBHG><FDBGDF<FGG?CHEACGHIIA7@@EGCEEE?D=BC??CAB=;;>>;C:::@C5:@CCCCCCC
@4NG
CTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCC
+
CCCFFFFFHHHHHJJIJJJJGIJJJJJJJJIJJJJJIIIJJGHIIJJJJJIIHIJHIJJHGHHHHFFFFFEDEEDDDDDDDDDCDDDDDDDDDDDDDDD
@4NH
ATGCATAAATCTGTGGTGTGAGGGAATGAGGGGTAGGGGGGGGAGATGAGGGGAAATGATAGAGATTAGGATTTGTGGAGGGGGAGAAGGATGTGGGGGGG
+
+1+2+,,+2,2,,,,22<7+,+3+)+2++*1111)))0)(&&&&)&++((((&&&(+((+(((((+((+((++(((+(((+&&&)&)(((((+++(&)&0&
@4NI
CAACCGGGGAAGGAGGGCCGGTGGCCAATCTCTCAAAGCCTTCCCAAGGTGACCGCTCCAAAATGTCCAAGGACGTTTATGACCACTTCCGCCAGGGGC
+
000-=83(<8?;(@(3((0(776368).).;)))))).)6)))))))6(.6.-(,/'3',5(2(((+(826(82&&28+((((((++56:)&2583&)0
@4NJ
GTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGAT
+
@?@FFFFDHFF?AFGIIGIGEGBGHEHGBFHGGHIGGIIHIGHGGGIIBHDHIGIIIIIDECHGHHEHGFFFFDFCDEACCECCC=ABB?BBBCCCDDCCD
@4NK
ACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCT
+
@@CDDFFFDHFHGGGHJBFGHEGHEFHGHJBHIJFGEHEGIJ;@@FHHGJGHH7AHFFD>CECEEECEDBDDD:>@AAC@CCDDDDB?BDDDDBDDD@AC
@4NL
CCTAGAGGGAAAGCGAGAGGGAGACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGC
+
B@CDFEEFHHHHHJJIJJJJJHIGIIJHIIJIJHIIJJJIGHHHEEFBDBDEDDDDDDDCDDDBDDD?CDDDDDDCDDCDCDDDDDDDDDDDDDDDDDDDB
@4NM
GAATTGTTCTGTATGAATTGATGACTGGACAGTTACCTTATTCAAACATCAACAACAGGGACCAGATAATTTTTATGGTGGGACGAGGATACCTGTCTCC
+
CCCFFFDFHHHHHJIJIJJJJJJJJIIJJJJJHIJJJJJJJJJJJJJJJJJJJJJJIJJJGIJJJJJJJJJJJJGHHGECEFFDDDDDB?CCDDCCDDDD
@4NN
ACGCCAGCTGTATCACCTGGGAGGGGACCAACGGGGAGTTCAAAATGACGGACCCCGATGAGGTGGCCAGGCGCTGGGGCGAGCGGAAAAGCAAGCCCAAC
+
CCCFFFFFHDHHHIGGIIJJIIJJIIGGIJIJIIGJGHGIIJIIHHHGGFFFDDDDDDDDCCD:ABBBCBDDD>BBDDBDD@@@BB>@BDDBCCCDDDDDB
@4NO
ATTCACCGCAGTGCATCAGAACCCTCCTTGAATCGGGCTGGTTTCCAAACAGAGGATTTTAGTCTATATGCTTGTGCTTCTCCAAAAACACCCATCCAGGC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJIIIJJJJJJJJFHIJJJJJJJJGIIEHHHHHHFFFFFFFFEEEEEECDDDDDDDDDDDDDDDDDDDDDDDD
@4NP
GTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCC
+
CBCFFFFFHHHHHJJJJJJJJJJJJIJIJJJJJIJJJJJJJJJJJJJJJJAHIHHHHHFFF@DEEEEEEDEEDDDDDDDDDDDDDDDFDDDDDDDDDDD
@4NQ
GTAAAAGATGATTTAGAAGACAGTAAAAATAAACAGGAATTAGAGTATAAAAGTAAACTTAAAGCACTTAATGAAGAGCTTCATTTGCAAAGAATAAATCC
+
@@CFFFFFBFFFBEGHHHIDGIIEEIJJIIEHIJJIIBGGHGH>DBF<DIIJJ<BFDHGIJIJJGGGGHIGH<@DHCGC7CAAEFBF>DDDBCECCCCDCD
@4NR
CCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGT
+
CCCFFFFFHHHHGJJJJJJJHIJJJJJJJIJJJJJJJJJJJJJJJJJJJJJIHHHHHHFFFFFFEEEEEDDDDACDDDDDD?BDDDDDDDDDDDDDDDDDC
@4NS
CCCCACTCAGGAGCTCAACTTGGGGTCCCCAGGGAGAAACCCCTAGCTCTGGGAGTAGTTCGACCCTCACAGCCTCGTAAAAGGCGGTGTGACAGTTTTGT
+
CCCFFFFFHHHHHIGGIJGHIJJIIFHIIIIIJJIIIHHIIIJJGHIGGIHIJGG@EHHEHFFFFCCDDDCCBADDBABDDDDDDDD9@B@CDDDCCDDD?
@4NT
AGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACC
+
@@CFFADDFFHHDIIJIIFGHIJIIJIIIIGJIIJIIDEHEGIGIGIBHJJICE8?BDFDCEECDCCACDC@DDDBDDDB<<ACDDDDDACDCDDACDDDD
@4NU
GAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGAC
+
@@@FFFDFFHHHGIJJJJIFFHJJIJJJIJJJIJIJJJIGIIJJJIJJJJIIHHHHFFFFDEBEEEDDDDDDDDDDDDDDDDDDDDDDDDDDDD@DDDDDD
@4NV
CCGTGGAGCCTTTCTGGGTTGGGGAGAGGAAAGGAAAGTGGAAAAAACCTGAGAACTTCCTGATCTCTCTCGCTGTGAGACATGTCTGAGACTCCTGCTC
+
BBCBDFFFHHGHHJJJJJGHJIJJIJIIJIJIJJJJIJFHIIIJJJJJJHGHGFFFFFFECDEDEEDEDDDDDDDDDDCCCCCCDDECDDCDCDDDDCDD
@4NW
CTGGACAGATAGCTGGCGTGGATAAAGATGGAAGGCCTCTACAACCCCACGTCAGAGTGTGGGATTCTGTTACTCTATCCACACTGCAGATTATTGGACTT
+
@@@DDDDDFHFDDHGIIIFGG?BF<EHIGGDFHBGHIGIGGEGIIEGEEHIIEHIGH=C.??D;7;@CDCCCC;CCCCC;CC>@9@A@ACAACCDACCC>:
@4NX
TGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGGTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGC
+
@@<DDEDEHBFFFIIDBHHIIDHIIIEEIIIIGIIIIFIEIEGIGIIFHGI3@GCFFHGIGAEHHEHHHDEDDFCC>ABECDCDDA>CCCDAC@ABDDD>
@4NY
CTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTT
+
CCCFFDFFHHGHFJIGGIIJIJGGGFHGCEFIGGIIIIJGIJIJJJGGGHHHIJJIIJJIJGCHHHFFFFEFFACDDDDDDDDDDDBBDDCDDDDDD+9>B
@4NZ
CCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTAT
+
@@@D=D::C<AAC:AD;;CFBGEFGDE@;FF@@@GAGFGDD<8?AFEEIIIF??B>BBDACC;AAA;A(>@BBBB9<;BB?8?4>(4>1<<?B@B@39::4
@4O0
CAACAACAGGGACCAGATAATTTTTATGGTGGGACGAGGATACCTGTCTCCAGATCTCAGTAAGGTACGGAGTAACTGTCCAAAAGCCATGAAGAGATTA
+
CCCFFFFFHHDHFGGHIGJHGIGIIJJII??EF@FDADGGHGGHFCCGFEGGIGIJJHEEACHED7@DBB=A?ACCDD@CCCCDDCBA?::@CCCDDDDC
@4O1
GTCACGGGAGCCCTCCCTGAAGAATTCCAACCCCGACGAGATTGAAATCGACTTTGAGACCCTGAAGCCGTCCACACTGCGTGAGCTGGAGCGCTATGTC
+
CCCFDDDDDFHHHJJJJJCHHHGIJHGIIJIIIJGGHGGHIJIGEHHFHFBEFDCCEDDCBBCDDDCDDD@;@?CD@CCCD<@B?C@CCA@CD@BDDCDD
@4O2
CAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGC
+
:=?D:ADBA?BD?EBDHGHEGGEAEHIIG@B:?CG?FCHA@BDGFEFHGIH@B=C;=;@CEHICCG>??;C?DC>;C>?;A;?@BC5>5@A>>@CC>>C
@4O3
AATTCTCGCCTCTATTGAGCTGCTGGCCCGCTCATTGCCAAAAATTCACCGCAGTGCATCAGAACCCTCCTTGAATCGGGCTGGTTTCCAAACAGAGGATT
+
CCCFFFF1DHHHHJJJJIJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJIJJJHHHHHFFFFFFDDEDDDDDDDDDDDDDDDDCDDDDEDDDDDDDDDDD
@4O4
TGACCAGCGCGACCTTATCTCCAACAATGAGCAACTGCCCATGCTGGGCCGGCGCCCTGGGGCCCCGGAGAGCAAGTGCCGCCGCGGAGCCCTGGACAC
+
((0(86.(-(---@?<?38))):?3???1)=)7..))).(<6).)8.3(6-'3383,,(+(5&&0&))85&865;6(+:(&))0-)0855+226(+(+(
@4O5
TGATAAACTTCAGAAAGAACTCAATGTACTTAAATCAGAACAGGACTTGATTAGAGACCAAGGATTTCGTGGTGATGGAGGATCAACCACAGGTTTGTCTG
+
@@CFFFFFHFFHDBHGGAHGIGHHGEHGIGIIIIJEIGGGFEGFGEIIJIJIIJEGHJGHGHI2CFHGEHHG@CEHHHFFFFCECEEDD?BBBACDD9@CD
@4O6
CGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCG
+
CCCFFFFFHHHFHJJJJIIIGGIHIJJJIJIJJJJJJFIGHIJJJHHHFFFFDEEEEEEDDDEDDDDDDDDDDDDDDDDBDDDDDDDDDD@CDDDDDDDDD
@4O7
TGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTAC
+
@C@FFDDDHFFHGJJJJIJJIIJJJFIJJJHIIIHEIJJJGHIJIJIIJJIIIJHIJIJGIFHEHFDFFDEDCEDCDCCCDCDDDDDDDBDDDDCDDDDC
@4O8
GGTTCCTCCTCTCCTGGTCTCTCAACAGGCAAAACGGGAGGAGGAGCGCAGCCCAGCTGCCCCACCACCTCTGCCTACCACCTCCTCTGGCAAGGCTGCA
+
BCCFFFFFHHHHHJJJJHIJJJJJJJJJJJJJJJJIIIGJJJJJJJGHIIJHHHFFFFDCEDDDDDDDDDDDDDDDDDDDDDDDDDDCCDDDDDDDDDDD
@4O9
CAGAGTCAAAATTACTATACCATTTGGAGAATATGAAAAAATCATCCTCATCAAACCCCCGACATTAAGCTTAGATGTTAGTACAGCGGTCAAGCGTCAAT
+
00(-()).)22))=9=).=))))396)23)())))).;2(00.)0:=))))03<?156''-''''.6)))69(6(((-(-6(-3;=('''&)((+(+(&)+
@4OA
GGAAGACCTGGCTTACATGAACCACATCATGGTCTCTGTCTCCCCGCCTGAAGAGCACGCCATGCCCATTGGGAGAATAGCAGATGTGCAGCACATTA
+
CCCFFFFFHHHHGJJGJIJJJIIJIJJJJJIJJJIJIJGIIJIIJJJIJJJJJIJJJIIJFEEHFFFDFEEEDDDBDDDDDDDACCDDCEDDDBDDDD
@4OB
CTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJHIJJJJJJJHIHJIJJJHIJJJJJJJJJIHHHFFFFDEDDEDDDDDEEDDDDDDDDDDDDDDDDDDDD
@4OC
TTCCTGTACCAGCAGCAGGGCCGGCTGGACAAACTGACAGTCACCTCCCAGAACCTGCAGCTGGAGAACCTGCGCATGAAGCTTCCCAAGCCTCCCAAGCC
+
:?14=A=,=<AC<E;FFHCE;+@E?FF<BGGGEAHIG@DGEFGEHECAG;=DE)6.((;B).6>@A?B3;5=98=BBB:ACCACA39@C??<>988<9ABB
@4OD
CAGCACGCCAGTGTCCCCACTGCATCATGCATCTCCAAACTCAACTCATACACCGAAACCTGACCGGGCCTTCCCAGCTCACCTCCCTCCATCGCAGTCC
+
@@@DDD<DF?F<CBABGIIEGGGHBHIIHFHGH@GHIFEIIIIGHIIIEGGIIIFIIIIGFFHHHB>C?BBCCCCCCBCCCCBCBBBCCBCCCBBBB<AC
@4OE
GGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATC
+
@CCFFFDFHHGGFIGHGIJFIJDCDHGIGIIDHGGGHHBBFGBD@GGFCGHIIJJJGIIIFGHHHEBFCEEEEDDDCCDCDDDDDDDDDDCDDDCCBDDCC
@4OF
GCAAGAACAGTTGATTTTGGATCACTTACCATCTGTAACAAAGGAATCATCACTTAGAGCAACTCAACCAAGTGAAAATGATAAACTTCAGAAAGAACTC
+
????D:3BDDDD?,A:A?:8CF@BFCF929F?C4??EA<DD9;B?D<@>4B>BDD<DBBBCD=8@>@=@CCCC4?A7ACC@>A;A@A:;A@AA3;;>3>(
@4OG
CACAAACATTAGTAGGATGGGTGAGCCATATTCATTAAGCCATAGTGGTCCATAGTTCATTGTTGAGCAAGTTTTAGCCCTGCAGTTTTCACAAAAAGAAT
+
=>+2+2?A@,<<AC,+=+<++37+<9+?+****:1?=*:7*:=<=*0==9**09AA>?<9)787(.)...)).77>>)).)...).)(5.;(((((,',5(
@4OH
CACTAACAAGAAAACAGGGAATTTTTGGGAAATATGAAAAGCCAAAATTTGTGCAGTGTTTAGCATTCTTGGGGAATGGAGATGTTCTTACTGGAGACTC
+
@@@FFFFFHHHHHIJJIJGDHHIJJJJJJGGIJCIIIIJJIJJJIIIIJJGCGIJGFECGIJJJJJGEHHFHHFFFCEEDEDCCDDEDDDDCDDCBD?CD
@4OI
CCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTT
+
@<@DB:A)<?BAD?FHB9CGHEG@FCEEHEBF?FHGI@>?BFFEI?DFHGIG@GGHCECEDAA?EEE?>@D@@>ACC;@6>CC>>>;?CCCAC>:9?BBCC
@4OJ
CTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGC
+
CCCFFFDDHHHHHJIJJIJJJJJJJJIJJJIJJHIIJIJJJJIJIJJJGJJJJFIJJIJJJIHHHHHHDFFFEDDCEDDDDCCDDEEDEDDDDDDDDDDD
@4OK
GGCCGGTGTTTGCGGACATCAGCAAAGACCTGGAGAAGATGATGGTTAAGAGGAGAGACTACTTGGACCTTGCGGCGTCCACTCCATCTGACTCCCTGATT
+
@@<DDD@D@FD>FEA<G:DGHIIIB@FCDBDFCGGIBFBHI>BFE;@F;===C2A=A=7???CACC@CCCCA>@@6@95<<CCCCCC>>CCC@C>ACC9@C
@4OL
CTGATTGAGCCTGAAGAGGTGGCCCGACGTTGGGGCATTCAGAAAAACAGGCCAGCTATGAACTATGATAAACTTAGCCGTTCACTCCGCTATTACTATG
+
?@@DDFFFGHHHGIJJIIIAGGHHJJIIIIJJJJIIJJIJIJJJJJJEGGHHHEFFFEEEEEECDDDDDDDDDDDDDDDDBDCDDCCDDDDDDDEDDDDD
@4OM
GCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCT
+
CCCFFFFFHHHHHJIIJJIJJJJJJJJGIJJJJJJJJJIJJJIJJJJJIJHIGIJHHHHFFHFFFFDEEDDDEDDDDDDCD@BDDDDDDBDDDDDDDDD
@4ON
CCCCCTCCTCTGATGATTAAACAGGAACCCAGAGATTTTGCATATGACTCAGAAGTGCCTAGCTGCCACTCCATTTATATGAGGCAAGAAGGCTTCCTGGC
+
=+=;+??AC;<=7?B=2,?7<A9?3<ABA6AA)1:?=AB<*0??A9<*7*=>=*0.8A48A)=)/>AB>B3A3AAA;>)7)).),;@@;(-5;;===;?(9
@4OO
GCCGCTTCTCCTCATAGGACATAGGCTTGCACTTGTCCTCTTCCTCCGACTCATACGTGGGAGGGGGCTTGCTCTTCATGGGCGCTGGCTCCTTCTTGCTC
+
?@@BFFADHDFFHIIGIIIIGFHHGGEHHD<?DG@G@FCDHIIHGHIBFHBAF>GGGHGGGCEBDDBD@B=BD:::A:>CAAD>>>B9B?CDCC>@:(:@C
@4OP
CAACAAGAAGATGAAATCACTGTGCTAAAGGCGGCTTTGGCTGATGTTTTGAGGCGTCTTGCAATCTCTGAAGATCATGTGGCCTCAGTGAAAAAAATC
+
CCCFFFFFHHHHHJJJJJJJJJIJJJJJJJJJJJJJJJIJJJJIJJHIJJGIJHHFDDDDDDDDDDDDEDDDDDDDDDDCDDDDDDDD>CCDDDDDDDD
@4OQ
CAAAGAAAAAGGAGAAAGACAAGAAGGAAAAGAAAAAAGAAAAGCACAAAAGGAAAGAGGAAGTGGAAGAGAATAAAAAAAGCAAAGCCAAGGAACCTCCT
+
??;:B22:DDDDD@3;;EEBFEIF3CBCE>DE>BD;???DDCDE;C;C;6@AADCDDD3=>ADAA>3;@;;;53>AAAA?>>?>AAA?8<><8832<????
@4OR
ACGGAGTGGCCGAGTTCGGCCCGTCGTTATGAGGCTTGTTAGGCCTAACGGAGGAAGGATAGAGGGACATGAAGGAAAAAAGGGGGGAGCAGGCGGGTGG
+
;0(8(:-((-((0-(2)((((((-(-((0.))))-()-.)))))))..((','',,(((((((,('&(((((((+++(5(&&+(&)&&&&(+(&&)&&)&
@4OS
CTAACTCTCAAAAGGAAAAACTCAAGGAAGAACTAGGACTAATTTTAGAAGAAAAGTGTGCTCTACAGAGACAGCTTGAAGACCTTGTTGAAGAATTGAGC
+
@@@B;2ADD<=<A;E?ACFHG<FHIIC9A?CFAFHFHEHFDBGD@G4B?FF;?BF>)/=BGGIIGFG;)=@;=?;C>>6?;BACCCCCCBACCCC@CCCCC
@4OT
AACTTAATGAAGCACATAAGTCCCTTAGTACAGTGGAAGATTTGAAAGCTGAGATTGTTTCTGCATCTGAATCCAGAAAGGAACTAGAATTAAAACATGA
+
C@@DADFFHHGHAHGIIFIGHH>EHHAGHIGIIGCGA<E9FHIHEAFGFGGGH<9EGBHIBHGIIIIIIGGGIIGCGGEHFHHGBEFF@CCECEEDDDD>
@4OU
CACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCC
+
CCCFFFFFHHHHHJGIIJJJJJJJJJIJJJJJJJIJIJIIJJIJJJJJIJJJJJJJJIJJJJJHIJGIHHHHGHFFFFFEEDEEDBCDBDDDBDDDDDBB
@4OV
GTGAATATCCTACTCTTCATGGGCTATTCCACAAAGCCACAACTGGCTATTGTTACCCAGTGGTGTGAGGGCTCCAGCTTGTATCACCATCTCCATATCAT
+
CCCFFFFFHHHGHJJJJJJIJJJJJJJJJJJJJJJHIGGIJJIJJJIJIIJJJJIJJJJJGII7@.BEHJIHGHFFFFFFEEEEEDDDDDDCDDDDDDDEE
@4OW
AGCAACTCAACCAAGTGAAAATGATAAACTTCAGAAAGAACTCAATGTACTTAAATCAGAACAGAATGATTTAAGGCTACAGATGGAAGCCCAACGCATTT
+
CCCFFFFFHHHHHJJFGIIJIJIJJJIJJIJJJIEHIJIJJJIJJJJIJJJJJJIJJJJJJJJJIJJIIIJJIJIIJIHGHHHHFFFFFDEDDDDDDDDDD
@4OX
ATCACTTAGAGCAACTCAACCAAGTGAAAATGATAAACTTCAGAAAGAACTCAATGTACTTAAATCAGAACAGAATGATTTAAGGCTACAGATGGAAGCCC
+
CCCFFFFFGHHHHJJJJJJJJJJJJIJJJJJJJJJJJJJJIJJJJJIJJJJJJJJJFIIJJJJJJJJJJHIJIJJJJJHHHGHHFFFFFEEEDEEDDDDDD
@4OY
CACAAGGACAGAGAAAAAAAAAAGAGGAATCTCATTCTAATGATCAAAGTCCACAAATTCGAGCATCACCTTCTCCCCAGCCCTCTTCACAACCTCTCCA
+
CCCFFFFFHHHHHHIJJJJJJJJIIJJIJIGHIJJJJIIIHIGGIJHHHHHHFFFFFEEEDDEDBDDDDDDDDDDDDBDDDDDCBDDDDCDDDDDDDDDD
@4OZ
CAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCT
+
@C@FDDFDDDHDAGGGIHIHIEHICC;FHGIGI8@DEC@FG>;BBCHGIEGG@CDAECHGHFFFFDEECECCACCACCDDDBD>9A@ACCBB@D@BDDDDD
@4P0
GGAGTGCTTCCTCAAGGGAAGGAGCCTTTAGCAGTGCCCTGGGAAGGCTCTTCAGGAGCCATGTGGGGAGATGACAGAGGTACCCCCATGGCTCAGAGTT
+
==;;+2<<C@?AC?CA377;?=++<<A@=7==@ABBBBB>ABAA=5A57>B>878>AAA(.7>7>AA6(3'(6=(;;(-;9>??===38;929=?===(8
@4P1
GAGCTGACTTAGCGCCCGTCCCTAAGGGCTCTGGGACTTGGAGAGACATCACTAACTGATGGCTCCTCCGTAGTGCTCCCAATCCTATGGCCAAGACTGCT
+
;3(33.2664@))((@2-(---1.)..(10..<3)<.(.))9))--).)<>3>36.).<..<3=73036,(7((7((,,,;<(,(,:(((+8<(+++(++:
@4P2
CCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGT
+
@<@ADDD?ACFBDHGEA=DG1:CFGGIIE?DHDG<DDHH===FHDGDGGEIHEAEEH>;@?3;B@DCCCCC??(;@A>:5<(5=?AC<?BB?CC@:>?8<+
@4P3
TTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGACAACAAAGCAGCTATGGGCAGCAGC
+
+?;A+::BDADDD:2C<E:CF<<:AF@A;9+21?*C?*1???:8D6DD:A>2)@C=3)=3((.6)..77;?AD>A(6.;(5=;(,:9?(5(5(9(35<>2<
@4P4
GGGGAATCTACCCCAACCCCAACGTCCCCCGCCATCCTAACACCCACGTGCCTTCACACTTAGGCAGCTACTACTAGAAGCTTACTCATCAGTGGCCTTCT
+
??<DDDAD?FD<?CGEGD:@B=DG?FHGGGFB>(78==CHHAC@@;EEH=6;@>A@CC>?ACCCCC???C:C5@>>>ACCC@CCACCCCCCAD@><AC::@
@4P5
TGATGACTCCAATGAGCATATGCTTACTGTATGGGACTGGCAGAAGAAAGCAAAAGGAGCAGAAATAAAGACAACAAATGAAGTTGTTTTGGCTGTGGAGT
+
@@@DAEDFHGHHF@@GHGCIEIIIEHHIIIIIFHEIIIIIGIGIIICGIBHGGHGHB@FGIIIGIIIICHGEHGFFFFEFCEE>AE@?CCDBCD?(:ACA:
@4P6
TGATGACACCTGTGTTGTCCCAGAAAAATTCGATGGAGACATCAAACAAGAGCCAGGAATGTATCGGGAAGGACCCACATACCAACGGCGAGGATCACTTC
+
@@<B:DD?CDDHDBHIFIGCGIFEHGHICFHHG@FGHECDHFHIIICHCDHGIGIEGGGEGCEEC@EF:?BBCC?@BBBCACCCCBBBBBB@<@?CBCCCC
@4P7
GCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGG
+
;<?DBDDDFAFFHGG@EHII>EHGGIGH<FGGICHHCHCH?DDHH9FFHHAFGCEHAGEHEFEECEE>DCCCBB@BBCCCC@B<?BBBBBBCCCBCCCCCC
@4P8
AGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCAC
+
@;?BD??BDBAB?AC;DA)<F@F=;E;9?1???BDDFI>G@<0?BB?;D3C===FB>:@F7C@;=EEB;;??>;;;;AA;C:>;@CAC:@C@C:(:A>@9A
@4P9
GCTTCTCGTCCTCAGAGTCGGAGAGCTCCAGTGAGTCCAGCTCCTCTGACAGCGAAGACTCCGAAACAGGCCCTGCCTAATCATTGGACACGGTCTCTTA
+
8+?AD;A:CDADD::AE:A3@)1?BC*CDED:??B?D?D3D?BD?D>=88=<A6AA</7.;?;?=<3(,5(88<5==3:54444>AA:::<55(+)>:>:
@4PA
AGACTCTGTGTGGGAAAAAGAAATAGAAATACTTATAGAGGAAAATGAGGACCTCAAACAACAATGTATTCAGCTAAATGAAGAGATTGAAAAGCAAAGG
+
BCCFFDFFFHFHGIJGIJGIJIHIJJIJGIJJJJGIIHGIGGGIEHGIJIJJJJJJJJJIJJIIJJEHIJHFHHGHFFDFEFD>AECCDDDDDDDDDDDD
@4PB
CAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGAC
+
CCCFFFFFHHHGHJJJGGIJJJJIJJJJJGIIHIGIJJJJJJJJIIJIIGGIJIJIIIJJJIIJJGGGEHHGGFFFDDDDDDDDDDEDDDDDDDDDCDDD
@4PC
CTCCGACAGCGCCAACGCCAGCTGTATCACCTGGGAGGGGACCAACGGGGAGTTCAAAATGACGGACCCCGATGAGGTGGCCAGGCGCTGGGGCGAGCGG
+
@@@FDDD?DDDDHGGIIBFHGIGIDFG@HGIGIEHCGEHBABEFFEACCCBBBACADCCCC>C?@BBBBBCBB;@AC98?ABCBB89@09>8B>>B><B@
@4PD
CCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGTTACGGGCAGCAGAGTGAGTTGCTAAGAG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJFHIJJJJJJJJIJJIJJJJJHHHHHFFFFFDDDDDDDCB:A@CDDDDDEDDDD
@4PE
CTAAAAACCTTGCTCCTTTACAAGAGAGTCAGGAGTCTTACACAACTGGGACTCCCAAAGCAACATCTTCTCACCAGGGCCTTGGAAGCACTTTGCCT
+
@B@FFFFFHGHHHIHIIJJIGHJHGHHEFHIIJGGEGGHH>FHIJJGGHGII@EHIJIGGGIJJJACHGHFHFHFFDDDDDDDDDCDDDDCCDDCCCD
@4PF
CAGATACTTGTGCCCAGCAATCAGGTGGTCGTACAAACTGCATCAGGAGATATGCAAACATATCAGATCCGAACTACACCTTCAGCTACTTCTCTGCCAC
+
@@@DDDD;FHCDDE@GEGDAEDFCG+<11?E:C;F@GG>DDHG@??D@HCHGEG:BFCAGCHGGHIGEHHE=CBBDCCCE>CCACCCCCCCCCCACAACC
@4PG
GGATGCTGTAGGCTTGGAGCTGCCTGTACAAATAGAGGAGGTCATAGAGAGCTTCCAAGTTGAGAAGTGTGTAACTGAGTATCAGGAAGGCTGCCAGGGAC
+
@B@FFFFFDHHHHJIJJGGIJJGGIIHHHIJJGIGIJICGHGIIEGJJIDHEHGIJIJIHGH>FFDHDGGHEEHHGGDD;@DFFDEEEDBDCBDDDDDD?B
@4PH
GCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGC
+
CCCFFFFEHHHHHGJGJJIEIIJJJGHFCHIDDGDHIGHIIGADHHCHHEGGHGIIIGEGGGHIIIGIJFHFEE@CFEDEDEEEEDDDDDDDDDDDBCDD
@4PI
CTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCC
+
@@@FFF>D?HHHHGGEHIIIBBGGIIIGHIEGIGGIGIIHHHIIFIDHGGGIGGIEHADHEHGHFECFFBCECECBBCCB@BBCCCCCCBBBB?CBCCC
@4PJ
CGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCC
+
C@@FFFFDHHHHHFHIEHJHHHIIJGIGGGGIIIIJIJJJJHIGIJJJHGHHHHFFFFFFEEEDDDDCCDDDDDDBDDDDDDDDDD:ACDDDDCDDDDDD
@4PK
TGAAAATGAAAAGTTCTGTCTTTGATGAAGACAAAACTTTTGTAGCAGAAACATTGGAAATGGGTGAGGTTGTTGAAAAGGATACAACAGAACTCATGGA
+
@@CDDEFFHHGHHHHGGDCEHGHGEHGGGGHGHIJJIGHIJE3CCFHCGIJIJJIIJGIHIGGGG>A>CF>E@G<EEHEB?D>>>CE@A=?CAAAACDCD
@4PL
CACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCC
+
@<?DDDDDHAHDFIGEH?@FGG@AEHIEIGGCGH@FHGDHDD@FGCBFHG@DEGAGGBFFC@C;@E;C>CHAECEEEEDCC;AC?@C@;?9??9?B92<?
@4PM
CGTGGATTTCAAACAGTCCAGGCTCTCCGAGGACGGGCTGCATAGGGAAGGGAAGCCCATCAACCCCTCTCATCGGGAAGACCTGGCTTACATGAACCAC
+
@@=DDFFFHGHHFHIJHGJJJJIGIIJJJJIDHIJIJIIJIGGIIIGGIIHHHFDFFDDEEEDDDDDDDDDDEACBDBBDDDDDDDDCBDDCEDDDDDDD
@4PN
GAAAACACTTGGTAGACGGGACTCGAGTGATGATTGGGAGATTCCTGATGGGCAGATTACAGTGGGACAAAGAATTGGATCTGGATCATTTGGAACAGTCT
+
@@@DFFFFGHHGDHHIIJIJ>ECGIEH:??DGCAFHHGEGIJIDGIIBHIIIDHHGCHHGIH)=CE?BEFFEEECCCCCA@CCCA::9>CDDDDDDDCCDC
@4PO
CACTTTTGAGCGTGGAGTAGGATGCCTGGATTTTTCAAAAGCAGATTCAGGTGTTCATTTATGTGTTATTGATGACTCCAATGAGCATATGCTTACTGTAT
+
CCCFFFFFHHHHHIJJJHIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJFGGIJJJJJJJJGHHIIJJHHHHHHHFFFFFEEEEEEDDEDEEDDDDDEE
@4PP
TGCACATCATCCAGTCACGGGAGCCCTCCCTGAAGAATTCCAACCCCGACGAGATTGAAATCGACTTTGAGACCCTGAAGCCGTCCACACTGCGTGAGCTG
+
CCCFFFFFHGHHHGHIIJJIHJEHIJJJIJJIJIJJGIIIFIJJJJJIJGGHFFFFCEEEDEDDDDDDCDDDDDDDDDDCDDDBDDDACDDCCDBDDDDCC
@4PQ
CACGGATCCAGAAACAAGCCCACCAGCTTGTGGAACCCAACGTACGGCTCCTGGTTTACAGAGAAACCCACCAAAAAGAATAATCCTATAGCAAAGAAGGC
+
@<;DD1DDDDAFA3FC@F;GE?F@8)CC?;:*?90?G6BD;@0==F6;/@E)?>=)()773;3;@9(;((5;BB@2,',8@BABB=A3:@@:3:?93<9<(
@4PR
CTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGT
+
@@@FFFFFGHGFHIIHJJIJGCEHIEHHIDGHFGIGCDFFFGHFHGGFGHGHJIJE@EHIGIIGGGEEHHBCACDDDDDDDDCCDCBDDA@DDCCDDDCCD
@4PS
GAACCCTCCTTGAATCGGGCTGGTTTCCAAACAGAGGATTTTAGTCTATATGCTTGTGCTTCTCCAAAAACACCCATCCAGGCAGGGGGATATGGAGAATT
+
CCCFFFFFHHHHHJJJJJJJIJJHIJJJJJJJJJJJJJJJJJJJHIJJJJJJJJJJIJJJJJIJJJHHHHFFFDDDEDDCDDDDDDDDD@BDDDDDDDDDD
@4PT
GCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCC
+
@@@DFFFFHFDHHJJJIIJFHGGGHIIDHEHHIJJHDGHEHJGEHHJJHBDEA@EDHII7CHIGHGHGEHHEFFFDAEDCDDCCDDCCCDCCBDDBD>AC
@4PU
GATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCC
+
@@@D=BDDHFHDF>BE>DCEFHIIB9GG>CE@?9*;CD=;D<FAFD@CB=BCEGEF@EGGGECHHHD;BBD7?CC>CA@?AC;=C>;>>?A<@@?AAB??B
@4PV
CCCTGGACAACATGATCCGCCGCCTCTCCCCGGCTGAGAGAGCTCAGGGACCCAGGCCGCACCAGGAGAACAACCACCAGGAGTCCTACCCTCTGTCAGTG
+
CCCFFFFFHHHHHJJGGIGIIIHJJJIJIIJGGHEBFGHIIIIGHHHHHFFFDDDCBDBBDBBBDDDDDDDDDDDBDBBDDBDCDDDCDDDDDCDCDCCDC
@4PW
CAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCT
+
CCCFFFFFHFHHHGGHIJJJJIIHJJJJJIJJIJIGGGIJIIJIJGIIIIJJJCEHIIGIIHHHHHFFDCEDEE>CDDFECEDDDCC@BD?CDCCBDDBD
@4PX
CTTTTGTAGCAGAAACATTGGAAATGGGTGAGGTTGTTGAAAAGGATACAACAGAACTCATGGAAAAACTTGAGGTAACCAAGCGAGAGAAATTAGAGCTG
+
CC@FFFFFHHHGFHIGGHHHIJIJJGHGHIEGGJIJJIJIIGGHCHJIJJJIIBFGHIJJIIIGHIGGAHEEEHFBCEDCEDDCB=>BDDDCCDCCDDCDD
@4PY
TATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGG
+
CCCFFFFFHGHHHJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJIIJJJJJJIIJIJHHHHHFFFDDDDDDDDDDDDDDDDDDDDDDDDDDDD9BCDD
@4PZ
CAACCACAGGTTTGTCTGCTACCCCCCCTGCCTCATTACCTGGCTCACTAACTAACGTGAAAGCCTTACAGAAATCTCCAGGACCTCAGCGAGAAAGGA
+
C@CFFFFFGHFHHIIJJIIJJIJJJJIJJJIIIJJJJJJIGIGJJJIIJIIHHHHGF;BFDECDEDDDCCCDDDDDDDDDDDDDDDDDDCD<BBDDDDD
@4Q0
CAACCAGGAAGTTCTGGAGTTTGTCACCAGTGGAGGCCGGATGGACCCACCCAAGAACTGCCCTGGGCCTGTATACCGGATAATGACTCAGTGCTGGC
+
>+1?=A;1<AC2+,22A<=C>=><2+22<::=AB)?11?<A0(<)>=A=AAA1.6..=A>7;=);;7=;=;-(5>?3=:=6;???3(+8(3;8(+3+2
@4Q1
TCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAA
+
C@@FFFFFGGFHHJIIJEHHIIIFIJIIIDIIFGIJJIJIIIGIGGGIHIIIJIJCHGGHIGFHFFDECEECCDDDDDBCBDDACCDDECDDCDCDDDD
@4Q2
TGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGG
+
@@CFFBBDHBHDFHBGGBGHEBHCHIIIIGIIIIGGHGHBCG>FGIBH@@GEHIHEE?BDD;?ADDACC;>CC>@CCCDC?5>AC>CAAADDDDDCDBD??
@4Q3
ACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJIJJJJJHHHD?BDDDDDDDDDDDDDDDDDDDDDDDDDDCD@CD@CDDE
@4Q4
TTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAAC
+
CCCFFFFFHHHHHIIJJJJJJIJJJJJJIJJIJJIJJJJJJJIJJJJJJJJJIJJHHHFFFDDEEEDDDDDDDDDEDDDDDDDDDDBDDCDDDDEDDDDDB
@4Q5
TCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATG
+
CCCFFFFFGHHHGJJJIIJJJJJIIJJJIIIIJJJJIIJI;FGGIJJJIJI=CEEHHFFFFFFEEDDDDDDCDDDDDEDDDDDDDBDDDBBBDDDDDDDDD
@4Q6
GGGGAGCCCCGGACCGAATCGGCTCTCTAGGCCGTGGAGCTTGCCGTCCCACCTCCGTCCAAATCGACCTTTCCTTTCTATCCCCAACCACCCCTCAACCC
+
;<?=1ADDBD6)<:?DA@DB8??D0B3B=B>@CAADDDDDDDD@A@@???A??????????AAAA????>AAAA>AAAADDAAA???>?????>>>?A>>>
@4Q7
TGGACTTGGCACTTTTGAGCGTGGAGTAGGATGCCTGGATTTTTCAAAAGCAGATTCAGGTGTTCATTTATGTGTTATTGATGACTCCAATGAGCATATGC
+
@C@DDDFFHHGHHJFGHGGII@EDFHCFHIJJJJJIJJJIJIJIEHGIJJIIGFGIJIJGFHHIIJJGEHCH;CADFFFFFEEEEEDECCDDDDDDDCDDD
@4Q8
GAAAGCGAGAGGGAGACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGC
+
@C<DFDD?C?CFFIIGHHHIGIGHH?GHF@BFG>BF@C85=A;=?;B?CCEEC@B@;=BBCDDB>BCCCCDDDCCDCCCC>@CD?CC9>?CB@BBBDBDB@
@4Q9
CCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTC
+
=1?DBD1=?FFFB@GIA:A?FFHHCFFFFF;BFFEFFII>?FF;?DFDFIIDFAFFCFGFFEE>7?EFFDDBB==;;;ABB(>(5:5(;>:5:A9?82<
@4QA
CCTGGCTTACATGAACCACATCATGGTCTCTGTCTCCCCGCCTGAAGAGCACGCCATGCCCATTGGGAGAATAGCAGACTGTAGACTGCTTTGGGATTACG
+
CCCFFFFFHGHHGIJJJIJEIIJJIIFHIIIGIIJJJJJIJGIJGIIGHJJJJIIJIGIHHHHHGFFFFDEEDEDDDDDDDCDDCCDDDDDDDDCDDDDDD
@4QB
CTCAAGTAAGCTCTTTATTAGATGGAGTTGTGACCATGACAAGCAGGGGTGCTGAAGGATCAGTTTCTAAAGTAAATAAAAGTTTTGGTGAAGAATCAAA
+
@@@FFFDDFHHHFIIJJJJJJEHEHFHIHIEFHJGIIIJJEDDEIIJJI@AGGIGIGHHHJDCCEHGEEFGGEHFFFFFFEECEEEED5?@CDCDDCDDD
@4QC
CTCAATCAATCTGATTCTATAGAAGACCCTAACAGTCCAGCAGGAAGAAGGCATTTGCAGCTCCAGACTCAATTAGAACAGCTCCAAGAAGAAACATTC
+
@CCFDFFFGGHHHHJJJIGHJJJIJGGHIIIJIJJHIJIJIJIJHHGIIIICHIJJIJJIJJJIJJGJIJJIJHECEHHFFFFFEEEEEDDDDCCCCCC
@4QD
AACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGG
+
@CCFFFFAFFFDHIIGIJGIIJJIIJIJJGIIJIIJIIFGEHIGHGIBCDHGEGICHIIJEHBHHF>@B?;>ACDDDDDDDDDCDDDDDCDDDDDDDDCDD
@4QE
CTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATG
+
CCCFFFFFHHHHHIJJIJJJJGJJJIJJJHJGIJJIJHIJJJJIJJJJJJJJHHHHHHFEF@CEEEEEEDFDDEDDDDDDD@CDDDDDDDDDDDDDDDDDD
@4QF
AGAGGACTTTCGCTATCGATCTCCTCATTCAGGTGATGTGCTCTATGAACTCCTTCAGCATATTCTGAAGCAGAGGAAACCTCGGATTCTTTTTTCACCAT
+
CCCFFFFFHHHHHJJJJJJJJJJJIJJJJJJJJGGJJJHJJJJJJJJJJJJJJJJJJJJJJJJJJIJJIJJJJJHHHHFFFFEDDDDDDDEDDDDDDDDDD
@4QG
TTTCTTTTGAAAATATGACTGTTGGAGAAGAAAGTAAGCAAGAACAGTTGATTTTGGATCACTTACCATCTGTAACAAAGGAATCATCACTTAGAGCAACT
+
@@@DDDDDFAFHDD4BF>E9H@EF;?@G@DHHI>E<B4DFE>D39;?DBF<09B49(?CG9BCF;F;;FEC77=7=E;9?EDEED>@>AC:@>>(;5>;=>
@4QH
AAAAAAGAAAAGCACAAAAGGAAAGAGGAAGTGGAAGAGAATAAAAAAAGCAAAGCCAAGGAACCTCCTCCTAAAAAGACGAAGAAAAATAATAGCAGCA
+
CCCFFFDFGHHDHGHIIJJJIBGIJ@GCDFF?BFGIGGHIJIIIJIJJJJGGHHEEFFFDDEEBDDDDDDDDDDDDDBDC>BBBDDDDD?CDCDDDDD@B
@4QI
CTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACC
+
BCCFDFFFHHHHHJJJIJJJJJJJJJJJIJJJJJJJJJJJJJJIIIJJJJJJJBHHHHFFFEFE@CEEEDDDDDEDDDDDBDDDDDDDDDEDDDDDDDDDD
@4QJ
GTGCTGAAAATGAGTTTTCTATAAGTCCAATAGACAACAACACGCTTGACTTGAATGGCAAAGCCCTCATGATGATGAAATAAGAAGACTTTCTCTATCG
+
;(73<))))9=:41)2))38)3@==))))3)))2=@)(.1((:(((<97))0)).)337>?>;>3:;/(.))))).).)))..(6((:(6((7((((,((
@4QK
CAGATCCGAACTACACCTTCAGCTACTTCTCTGCCACAAACTGAGGAGATGACATCTCCTGTGACTCTCACCTCTCAGACAACTAAGACAGATGACCCCC
+
+=;?=DDBBA6D<?A<ACGAD>4CHE*?EG>?F<D@DAD38<<*9B*?FA?4B<B3CAF4@)=)=@;;DFE9??;@BBB>@;;;@@ABB?;>3(,:@?BB
@4QL
GTGGAATTCTCCTTAAAAAACAGCATGTTCTAGAAAAGCCATGCTTTGGAGGTGCTGTAGGCTTGCAGCCAATTTACTGGAGCAGGGATGACGTAGCCC
+
@@@FDDFFFHGHHJGIIIJIJIIIJIJJJJJJIJJJJEHIIJJJJJJGIGIIBGIIIGIIEFHIIJHHHHHFFFFFFEDEEDDDDDDDDDDDDDDDDDD
@4QM
CCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTC
+
@?<?DDD?CDFFB>GI1??+9<A??C8*:EFEI@?9?409BDC8B>D?DBB<FB=<FF:CFIEA@E=C?B3.66;>>;>;>;->?:>@@A::5:@A?A@B9
@4QN
GACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACT
+
:::AA=7<CA+<+2@<ACBAA@@@>4?B;AA3:=??B=3?0:=AB<;=B*?>(58-<(6-4459)7>@@;6;;65;-5=?=3559559=32(3(++3:3(+
@4QO
GGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACAC
+
@C@FFFFFHHHHFJJJJJJIJIJJJJIGACFGHIIJGGGIGJIJIIIJGGEHGIIFIIIDHHIIJIJIHEFHGFFFFDDDECDDDDDCCCCDDC@CCDDD
@4QP
AGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGG
+
@<@DDBD;AD>FBDA;FEFGEGHGIBE>@G??CDHGGEC?@?<?FH?F@HEFHGGH<B@DHEH:CEGFECADD>8/=?>;;ACCCCB@CBC@CCA:ADC@C
@4QQ
CAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCGGCC
+
@@@DDFFFDHDHDHIJJIJJHJJEHGGHGHIHGGIIII@GHDIIJIGGIJJJGHGH?CDEFDFDEDCEEDDDDDBB@CDCA@BD?BDDDDDDDBDD?BD><
@4QR
CCGAAACCTGACCGGGCCTTCCCAGCTCACCTCCCTCCATCGCAGTCCATACCAGATAGCAGCTACCCCATGGACCACAGATTTCGCCGCCAGCTTTCTG
+
C@@FFFDDFFFFBGIHIGI@D;GHEGBGGG;DBGHGDCGH@CGEA;@D=DEFCHHBBEFDDCAACECBBB???CCABBBB>CCC@CBB9@<<5?CCACCC
@4QS
TGAAGACAAAACTTTTGTAGCAGAAACATTGGAAATGGGTGAGGTTGTTGAAAAGGATACAACAGAACTCATGGAAAAACTTGAGGTAACCAAGCGAG
+
@C@FFFDEFHHGHIADHFDHHIIGGIIGIGJJIJJJJJJCACHGBHIIFGIIJGIGIIIBHJGIIIJGHCHHGG@EDFFACE@CCDDCDDDDDBBB?B
@4QT
GAAAAACTTAAAGATAATTTAGGCATTCACTATAAACAGCAGATAGATGGTTTACAGAATGAAATGAGTCAAAAGATAGAAACCATGCAGTTTGAAAAGG
+
@?@FBDDEFDFFDB?EGGCHIIIIFGEEHGIEDGHIIIGIBCGDHGIGGE9?DBFF<FHIIIII:FCG=@GGGIGE;E>?ECEFFC@>;C>C@CC@CCC=
@4QU
CTTAAATCAGAACAGGACTTGATTAGAGACCAAGGATTTCGTGGTGATGGAGGATCAACCACAGGTTTGTCTGCTACCCCCCCTGCCTCATTACCTGGCTC
+
CCCFFFFFHHHHHGIIHIJIJIJJJJIIJJJJIIJEEHIJFGGIBGHIIIIIIJJIJJJJIJIJIAHHFDFFFFFFEEEDDDD@DBDCDDDEEDDDDDDCD
@4QV
CTCCGCTATTACTATGAGAAAGGAATTATGCAAAAGGTGGCTGGAGAGAGATATGTCTACAAGTTTGTGTGTGATCCAGAAGCCCTTTTCTCCATGGCCTT
+
:?@7D?DDHDHDBDF><2<C@<<C@9C@BGHB@B>?C*1)B??F88/7?B(/B<F)=C@7@CCE>=E;A7.(6?DEE@A;>;>@;;;;>:A>CA>:,(:::
@4QW
CCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGG
+
@CCDDDFFDFBHBEEFGH@DGHHHHH@>DHIAHEHIIGIABBGGHG@GGEGICB:;A;EEGD>AA>CEDED@CCACACCE>CD5>CC@CBBC<?CDDCDDD
@4QX
GCACCTCCATCCTACCCTCCTACCACCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGC
+
@@@DFFFFHHFHHIIIJIIIGIHIIIJEGGEDGGIEHGHJGEGEHIGGGGBFGGGHDHIGEDGGHEEEEHFCFEDFDCEDECDDCCCDA@BCB@?>BDD
@4QY
CCTCATTACTATTCTGCCTAGCAAACTCAAACTACGAACGCACTCACAGTCGCATCATAATCCTCTCTCAAGGACTTCAAACTCTACTCCCACTAATAGCT
+
?@<;:DDDAFFB,AFFI<<?GD@FGFAFEEADF9?@?3CDG<)8?88?F).<;4(5=7@.7)77??B>?>BDA@@AA@>;>>;>A:>>:?259?A>(:A3>
@4QZ
TTTTCTTAGCCTCCATTAAGTCCAAATCCAAAGACTCTGTGTGGGAAAAAGAAATAGAAATACTTATAGAGGAAAATGAGGACCTCAAACAACAATGTATC
+
;535@:8).)<97???4>86))6>@<>??<7=)2<87:1.<:=?<6=16<836)07;):6=3=?@8)>9.).;7>>8:1)).6=07;=7<87;726<(5;(
@4R0
AGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCT
+
CCCFFFFFHGHHGGJGIGJJJJJJJJJGIGIJJJJCGIJJJJJEGIGIJJJJIJIJJJJIIJHIIIIJGHHHHHFFFFFEDEEECDDDCDDDCDDDDDEDD
@4R1
CCGATGTTGACAACTATGATGACATCAGAACGGAACTGCCTCCTGAGAAGCTCAAACTGGAGTGGGCATATGGTTATCGAGGAAAGGACTGTAGAGCTAAT
+
CCCFFFFFGHGHGJJJJJJJJIJJJJJJIIJJJJJJGIIJIJJIJGJJGIIJJJJJIGIIDHFGGJIHHGGHFDDFFFDDDDDDCDB@BCDADDCCDDDDC
@4R2
CCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTTATGGGCAGGAGT
+
@@@?DDD?DF8FF>FEGEFI9EGHIFFIFFICGFIIBEBA<B>GFFEEFCE=@FGIIGEC68<D?DDC@CCBB?85>@BBABB?A@9?BBABBBB?592<+
@4R3
CTTAAAGATAATTTAGGCATTCACTATAAACAGCAGATAGATGGTTTACAGAATGAAATGAGTCAAAAGATAGAAACCATGCAGTTTGAAAAGGACAATTT
+
CCCFFFFFHHHHHJJJJIJJJJJJIJJJIJJJJJJJJJJJJJJIGIGIHIIJJJJJJJJJIJIJJIJJJJIJJJJJJJJHHHHHFFFFFFFEDDEDDDDDD
@4R4
AGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAA
+
@@@DDFFDFHFFFIGGIIJFIJIJJDEHHCFFEGHIIGHGIIIJEGIIIIJJHHHEBBBFDEEECBCCDCCDDDDDD@CDBDDDDDDCDDEDDDDDBDB
@4R5
TGAAGAGCAAGCCCCCTCCCACGTATGAGTCGGAGGAAGAGGACAAGTGCAAGCCTATGTCCTATGAGGAGAAGCGGCAGCTCAGCTTGGACATCAACA
+
@@@D=DDDDDHFHHG?@@GAHIHC@C?*C:1060?DF?=2C9@6@=.)==7=?6A3;;;..7;6>;>AC@;;ACCB@80)8(:4A3@AA?AC>:(4:94
@4R6
CAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCC
+
@@?BDDDDFFDA?:22A:CEAFEF:FFDGFFF@:DDD?DEE@?BFFFF==FFF@@C>EFIF>E).=?BDB@2;@@BB2;=9??BBB?B<;:@@A?AB950
@4R7
CTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTC
+
CCCFFFFFHHHHHJJJJJJJJJJJIJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJIJIJHHHFFDDDDDDDDDDDDDDDDDDDCDDDDEDDDCC
@4R8
AAGAAGGATCCAGCGCCCATTAAGAGCAAGCCCCCTCGCAGGGATGGGGCGGAGGAAGAGGAAAAGTGGAAGCCTCTGTGCTATGATGGGAAGGGGGAGCT
+
(-((2)(9)))2))(-;=(;.).)).:3<<51.-0((((''''-.((6('35&75((++668(+(+58((+++(((+(((((42::++(2+89205&&)06
@4R9
CGTCCACACTGCGTGAGCTGGAGCGCTATGTCACCTCCTGTTTGCGGAAGAAAAGGAAACCTCAAGCTGAGAAAGTTGATGTGATTGCCGGCTCCTCCA
+
@@@DDDDDHHGHHACFGIJJCEGHIIIGFHGGHIGIJJJJIIIJIJGIIIIHHHGFDFFF@C>CECA>CC?ACDCAACD@A;@CDEDCDD><>B?ACDD
@4RA
GATTGTTTCTGCATCTGAATCCAGAAAGGAACTAGAATTAAAACATGAAGCAGAAGTTACAAATTACAAGATAAAACTTGAAATGTTAGAAAAAGAAA
+
CC@FFFFFHHHHDHHJJIGJJJGIHHIIJJJJIIJIGGIIIJJIIIJIJJIJJJJJIJJJJJJJJIJJJJIJIJJIJJHHGHHHFFEFFFFEEEDDDD
@4RB
AGAAAAGCTCAGTCGGATGGGCAGAGTCCTTCCAAGAAGCAGAAAAAAAAGAGAAAAACGTCAAGCAGTAAACATGATGTGTCAGCACACCATGATTTGA
+
CCCFFFFFHHHHHJJJJIJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJHHHFFFFFEDDDDDDDDDDDDDDDDDDDDDCCDDDDDDDDDDDDDDDEEDE
@4RC
TACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGC
+
CCCFFFFFHHHHHJIJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJIJIJIJJIJIHHHHFFFFFFCEEDDDDDDDDDDDDDDDDDDDD
@4RD
GGCAAGAAGGCTTCCTGGCTCATCCCAGCAGAACAGAAGGCTGTATGTTTGAAAAGGGCCCCAGGCAGTTTTATGATGACACCTGTGTTGTCCCAGAAAA
+
@@@?DD8D>>=FFFBE?3A3?FHIGCFC<FF>E>FH9DEI?FHD>?BB<D@G@BHFG;FHIGCCHFHD;?BD>;;CD>CCCC7?>C>@CBC355:@AC@<
@4RE
GATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCC
+
C@CFFFFFHHHFHJJJJEIJIJJIIIJJJJDIIGGHIIJIJJJGIJJJIJJIIJEHHGHGJFHHEHEFFFFDFFEDCDD>CDDDCCDDDDDDDDDBDDCDD
@4RF
CAGACACATCCTGGTAGTTGTGGGGCGGAAGATGAAGATTTCGGATTTCGGCTTGTCCCGAGGTATTTATGAAGAGGATTCCTACGTGAAGAGGAGCCAGG
+
059((:).)))@1)).)..).(:(-(5=????=16=;)9=83===8/54(';<;3(,,3)&&&)((52(6+(+((++++8(8(8/&(((22+(+(2(28;6
@4RG
GTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACT
+
@@BFFFFFGHHGHIJIJJJIJGIJJJJIJJJJJJJJJJEGHGIJJIIJJJJJJIJJJJIJGIIIIIGHEHHFFDDDBDCDDDDDDDDCBDDDDDDDCCDC
@4RH
TTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAAC
+
CCCFFFFFHFFHGIJJJIGGI4CGIIIIIGGAHFCHGCGGBFGIIGHHDHIFHIIJFDEGI@GHGFGFDBDEBCC@ACCDDDD?BCD@CDDDEDDDC@4>C
@4RI
CGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCG
+
CCCFFFFFHHGHHGJJIFHIHHIHIHIGIJJGHIIGHFIJFHIJIHHEBFFFEDFEEEECCDDDDDDBDDDCCCCBBBDBDDBDDDDDCD@CCDDDDDDDD
@4RJ
CAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTTATGGGCAGG
+
CCCFFFFFHHHHHJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJIJIJJJJJHHFFDEDDDDDDDDDCDDDDEDDD9<>BDDDDDDDDDD
@4RK
CGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGG
+
CCCFFFFFHHHHHJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHHHFFFFDCEEEEEDDDCDDDDDDDCDDDDDDDDDD
@4RL
TGCTTACTGTATGGGACTGGCAGAGGAAAGCAAAAGGAGCAGAGATAAAGACAACAAATGAAGTTGTTTTGGCTGTGGAGTTTCACCCAACAGATGCAAAT
+
CCCFFFFFHHHHHJJJJJJJJIIJIJJIJJJJJJJJJIIJIJIJJJJJJJJJJJJJJJJJIJJJJJHHHHHFFFDBEECBACDECDDDDDDDDDDCDDDDD
@4RM
GAACACAACACCATGGTTGGCAGTGCGGCCAGCCAAAGCTTTCCCCCTCCTCTGATGATTAAACAGGAACCCAGAGATTTTGCATATGACTCAGAAGTGCC
+
@CCFDFFDHHHGFGGGGEABFEFGHGHEHGIEEGIJGIIJGIICFCHGGIHHCCC>@CDFFFFEEEDCDBDDDDDD?CCDCCD@>CADEC@C>ACDCCC@A
@4RN
CGGATAATGACTCAGTGCTGGCAACATCAGCCTGAAGACAGGCCCAACTTTGCCATCATTTTGGAGAGGATTGAATACTGCACCCAGGACCCGGATGTAAT
+
@@@DDFFFHHGGHIGGIJIGIGGGIJIJIJJJIIGIJGHIIIJJIIJIJIIJGDGIGGIIGIHIDH=EH@EFEBDFFECEECEDDBDD@BDDDDBBDDEDD
@4RO
CGAGGACGGGCTGCATAGGGAAGGGAAGCCCATCAACCTCTCTCATCGGGAAGACCTGGCTTACATGAACCACATCATGGTCTCTGTCTCCCCGCCTGA
+
@@CFDFDAF>AFABBEBCFF>?@@BHHBFHEGHIIGDFHG<B@CFHGGIIEH;B;C@A@CCBACA;;@C>B<?<:5>>>C::AC>>4::AAC>B>>>BC
@4RP
TCTCAGTAAGGTACGGAGTAACTGTCCAAAAGCCATGAAGAGATTAATAGCAGAGTGCCTCAAAAAGAAAAGAGATGAGGGACCACTCTTTCCCCAAATTC
+
@@@FDFFBBDFDF@@EFFGEEHHIA?FCGHIDCCDDCGFCHCF<?DHB*?FFBDFHGGIEHIIHGIG<EGEAEE;@CDFCCBDD?BCCCCCDCDDCDBCC4
@4RQ
ACCTTATTGGGGAGCATTCTGATGCAGCAGAGCTTGGAAGGATGCTTCAGCTCATCTTAGGCTGTGCTGTGAACTGTGAACAGAAGCAAGAGTACATCCA
+
CCCFFFFFHFHHHGGIFGGGIIJHFJJIGIIJJIIIJGIIGFEHGIIJJJIGIIHHIIJJEIJGCGEEHHFGHEF@BDDFCCCECCCCCCCBCCCDDDDD
@4RR
CTCTGTTCGAGTCCCTAGAGGGCCGGCCGTGGAAGGGGGACACGTGAATATGGCATTCTCTCAGTCCAACCCTCCTTCGGAGTTGCACAAGGTCCACGGAT
+
?88=D=?B=C?CB>EG<FFA:EFBF:)??8?7B8=(@6'-';@BCC<?;(5>;?(>>;>>:>:,,,5:4>9;8?<94:<9BB?AB@4:@888+:3:>?9BB
@4RS
AAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCAC
+
CCCFFFFFHHHHHJJJGEHIJJJIIGJIIJIIIJIIHIJJIJIJFHJIIJHGHHFFFFFDEEEEEEEDDDDDDDBDDDDDDDDDDDDDDDDDDDDDCDDDD
@4RT
CGGCAATTCACTAACAAGAAAACAGGGAATTTTTGGGAAATATGAAAAGCCAAAATTTGTGCAGTGTTTAGCATTCTTGGGGAATGGAGATGTTCTTACTG
+
@?@DDDDDHHF??AGHG;EFHHHGIIH<AGGIEHIII=DHGCGHEGDDF>CGGIEFGG>=@;DGD=?CE>CABEECEEECC<;8?CC:<3>5;>;ACCAAC
@4RU
TGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTAT
+
@@CFFFDFGHGGHJIIGIGGIIGGGEGGHIGHGGGIGIIIDHIJIJFHH;FGGGIIHGHHEFFFDCCECCADDDDCDCDDC?BDD?BDDDD:BCACCCCD
@4RV
CAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTTATGGGCAGGAGTC
+
@8=D7=2BFFDFF>EEFBD<E:F@?FC+CFGEIGBBGI3@A@G8@BFF;8.=@@CDCFFIA=ADDD?@@CBB==>ABBAA>??(')2?4>>B?@B<>??3>
@4RW
CTCATTTTGTTAACTATTCAGAGACCTTCTCCCTTTATTCCAGCTGTCTAACTGACAAGACCTTTCTCTCTTTCTTTCTGCCTCATGCTCTCTCCAACAGG
+
?@@?DFFFF?FFBBGHIIIIGHBGGEEGIIIIIBGCEHEB<?B9CB*?DFH<BF>FDFEHGII>G==FG>CCHGGDGGA@EEHC>C;?@CD@CAEC@CBAD
@4RX
GAAATGTTAGAAAAAGAAAAGAATGCTGTGTTAGACAGAATGGCTGAATCACAAGAAGCTGAATTAGAGAGGCTGAGAACACAGCTTCTATTTAGTCACG
+
B@@DDFDDHHHHGJJJJJJJJJIIJJJJGHGHJJJJJJJJJJJJJJJJJJJJJJJJIGIJJIJJJJJIGEIHHHHFFFFBCEDDDDDDDDEEEEDCDECB
@4RY
ACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGC
+
<=@;;DDDHDFFBHEGIIIIBHGIGCGGGIICFDHGHAD@=GIII@D;CHGEHGGG@?AHHHEFFDECCECCCC;ABBBBAACCC@:A:AC@CD@:ACBBB
@4RZ
CTTTCGCTATCGATCTCCTCATTCAGGTGATGTGCTCTATGAACTCCTTCAGCATATTCTGAAGCAGAGGAAACCTCGGATTCTTTTTTCACCATTCTTCC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJIFHGJGFHJJJJJJIJJIJJJJJIJJJJGHIIJJJJJJJJJJJJIJJHGHGFFFDDDEEDDDDCDDDDDDEEEDD
@4S0
CCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGC
+
@@?DFFFFHFFFFHIIIJJJIGIEHGDGIGHGEGIEGIEIJJCDGIEHIJJHGGIIGIJAHIA=?CEHAEC>CB>A>>B@B@BDDDDCCC@CCDDCBDDDD
@4S1
AAAAAAATGAGTATGAAACCAGAGACTATTAAAGTTCCGAAGGAAGAGTAGAAAAGAATGTATTTAAAAGATGGAAAAAAGGTATTTCTAGGGGTAA
+
++8+4))2+++2:,<<A9+<8)1:?3B?:4**::?9**08;((().((/)/./=77(.)).).)))).37,).(.;;(,''(((((((((,((&)&3
@4S2
GAGATTTTGCATATGACTCAGAAGTGCCTAGCTGCCACTCCATTTATATGAGGCAAGAAGGCTTCCTGGCTCATCCCAGCAGAACAGAAGGCTGTATGTTT
+
@C@FFFFFHHHHHJIJJJJJJJJJHIIJJJJJJJJJJJJJJIIJJJJJIIJJJJJJJJIJJJJJJJJJJJJJJJIHHHHHFFFFEEDDEDDDDDACCEEEE
@4S3
CTAGAGGGAAAGCGAGAGGGAGACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGC
+
@@;DDDDDHHHAHIGHEFCG@GFDDH0DGHGIIIDH?EAABEHEHFB?BC@C=@BCCCCCCCBBBBBCBCB;@CCCCEEC@ACCCDCCCCB@>:>CCCBC
@4S4
CACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACC
+
CCCFFFFFHHHHHJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJIIJJJJJJJJJJJJJJJJJJJJGHHHHFFFDDDDDDDDDDDEDEEFEEDDDDDDDDD
@4S5
AGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACT
+
?@CFBADDFDA>DGGIBDHEHIGGFHFEGH<;BEH?BG>FHIIEEAGGCBBBCGIII=.>7..=?=??BEDCCDE@(;;;A(>AAA?C:1(5<AACABCB8
@4S6
CAGCAGAACAAACCAAAGAAAAAGGAGAAAGACAAGAAGGAAAAGAAAAAAGAAAAGCACAAAAGGAAAGAGGAAGTGGAAGAGAATAAAAAAAGCAAAGC
+
?<?A=DD>+?2<:<:A;EE;<F>A>DEDEDCDD>;BD3BCDC;9DDCD>=ADD@A>CCC3;?@?A@AAA?A?????,:>>AA??333>A>:>;502>>33(
@4S7
CGTCCTCAGAGTCGGAGAGCTCCAGTGAGTCCAGCTCCTCTGACAGCGAAGACTCCGAAACAGCACCATCATCACCACCATCAGCAGATGCAGCAGGC
+
CCCFFFFFHHHFHIJJIIGIJJJJIBHIIIJIJJJIJJJJJJJJJJJJJIEIIIJJHHHFFFEEEEDDDDDDDDDDDDDDDDDDDDDCDDCDDDDDDD
@4S8
GTCAGATCGCCTCGGGTATGGTGTACCTGGCCTCCCAGCACTTTGTGCACCGAGACCTGGCCACCAGGAACTGCCTGGTTGGAGCGAATCTGCTAGTGA
+
@?@DDFFFDDHAHAHHFHGGGCFHCHEBHGGHGIIIIIIGGIII@?F@GDB@AA8B=CHGFFFFCCCCCBCCCCC@CA>CBCCCCCBBCBCDAC@CA@C
@4S9
CCTAGAGGGAAAGCGAGAGGGAGACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGC
+
:?<:BABDFAD::2CCA8C<8C?CFFE<@D:BFFC(=(.8;@A='59(.6;>?=?;AB@:>A58=@08>899>;>@@:::4>A@AA44:>?28@>AB>A<9
@4SA
CATTCTTCTGAAGAATTAAAACTGTTAATGGGGACAACTGAAGAACTTCAGAAGAGAAATCATAAAGTCAGCCAGTTCGAACCTCATATAGTACAACGAAT
+
8((((22)):)9)))):><>))))29.=>>?((@5@(..)91))0<?=1)93=<><)99=;?81;:8.)89);>>))6(6(('.((6(-(5;;3;7<2;2(
@4SB
CTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCT
+
CCCFFFFFHHHHHIJJJJJIJJJJJJJJJJJJJIJJJJJJJJJJIJIJJJJJIJJJJIJJJIHHHFFFFDEDDEDDDDDEEDDDDDDDDDDDBDDDDDDDD
@4SC
CCTAAAGGTGTATATCAAATCAGCAAACAAATCAAAGCTCATGATGGCAGTGTGTTCACACTTTGTCAGATGAGAAATGGGATGTTATTAACTGGAGGAGG
+
@@BFFFFFCDCFHJJIJJJJJJJJJIJJJJJIJJJJJJJJJJJHIJIJJJIIFHHIJJJJJJJJJIJJJIJJIIJJJHHHHHCDDFFFEFEEEEDCDD?BD
@4SD
GCAGGAGTACCACGACCCAGTGTATGAACACAACACCATGGTTGGCAGTGCGGCCAGCCAAAGCTTTCCCCCTCCTCTGATGATTAAACAGGAACCCAG
+
8?1B:=22<C4<CE1EEA?F<?*:?B?ED4CDB@DDCD>B8?DDD98B==CA?A:??<5(;;>>A:>A3:,838?9<3:>A:>BDAA>((9828<?;?>
@4SE
CCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGGGCT
+
@@?DDFDFB?FDHIIIIIICBEDFBACFGHEDGGIHGHIIIIIGGHFCDHIFHIIGGIIGF?5???DEC@C?AB=??B:ACCCC?805>49<9>9?A(059
@4SF
AAAAATTCACCGCAGTGCATCAGAACCCTCCTTGAATCGGGCTGGTTTCCAAACAGAGGATTTTAGTCTATATGCTTGTGCTTCTCCAAAAACACCCATCC
+
CCCFFFFFHHHHHJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJFHJJJJJJJJJJHHHHHFFFFDFEEEEEEEEEDDDDDDDDDDDDDDDDDDDDDDDD
@4SG
CTCTGTTCGAGTCCCTAGAGGGCCGGCCGTGGAAGGGGGACACGTGAATATGGCATTCTCTCAGTCCAACCCTCCTTCGGAGTTGCACAAGGTCCACGGAT
+
@@<B?2ADCFBDAGBGBB<CDG>BH@?F?0?@F==;;;4-5?;>CCC@DDC;5?CCAA@>@CC>,,,:ACB;BBBCC>2589+9>3>@>?88>A@C@7.&5
@4SH
GGGACCAACGGGGAGTTCAAAATGACGGACCCCGATGAGGTGGCCAGGCGCTGGGGCGAGCGGAAAAGCAAGCCCAACATGAATTACGACAAGCTGAGCCG
+
CCCFFFFFHHHHHGIHIJJJJIFIJJJJJJJJJJJJJJJJHIJJHHHHFFDDDDDDDDDDDDDDDDDCDDDDDDDDDDDDDDDEEDDDDDDDDDDDDDDDD
@4SI
TACTACAACCCTTCGCTGACGCCATAAAACCCTTCACCACAGACCCCCACAAAGCCCCCCCTTATCCCATTACCCTCGCCATCCCCGCCCCGACCTTAGCT
+
((8(-<.)<-((@@1(-((:(@13-=.):?(<(.))..)((9.(<>1=''-;()).(,,'3'((,((5;=((+5::(&&&+(+++8-8&)&5&&)&(5:6(
@4SJ
GCATTCTTGGGGAATGGAGATGTTCTTACTGGAGACTCAGGTGGAGTCATGCTTATATGGAGCAAAACTACTGTAGAGCCCACACCTGGGAAAGGACCTA
+
@@@BDFFFDFADHIGEGEE;A@CDGHCGHJGHEGIIIJJGGGIFICBGHGDHEGHGGI@>CCBGGHIEDGHEEAEAECEFFDDDDDADDD?CBA@?BDA>
@4SK
GATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTTAT
+
@@CDFFFDDHHGHEHJJIGIIGGHGIIIIJJIIIJJJJIGIGHGJIGGHHJIJGBGGJEIICEHGHHHFFFDDDDBDDDDDDDDDDCCCCDCDD359?ACC
@4SL
GGGTATAGCTGACATCAGTGGGCTGTCCATAGGTTCCATAGCTTTGTTGCCCATATGCCTGGGTGGTCTGTGCATATCCTTGAGTGGGCTGGGCGGTGTA
+
B@@DDFFFHHHHHJJIJJJGIJIJJJJJJJJJJHIJJJJJJJJIJJIJJJJJJJJJJJHIHJJCGIEHIJEHHHHHHFFFFFDEAACDDDDDDBBD5@@C
@4SM
CAGCAATCAGGTGGTCGTACAAACTGCATCAGGAGATATGCAAACATATCAGATCCGAACTACACCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATG
+
@@@FFFFDHFFADGIIIFGGHJJEIIJEGGHIIJGIGIIGGGGIGGIGEEFGEGGHHICHIBHEGAEEHEDEEEFEEDCECCDDDC@B<AA>::?9?:@@
@4SN
CTCTCAGACAACTAAGACAGATGACCCCCAATTGAAAAGAGAAATAAGGTTAATGAAAAACAGAGAAGCTGCTCGAGAATGTCGCAGAAAGAAGAAAGAAT
+
CCCFFFFFHHHHHJJJJJIJJJJJJJJJJJIJJJJJJJJJJHIJJJJJJHIJIJJJJIJJJJJJIJJHHGHHDFFDDDDDDDEDDDDDDDDDDDDDDDDDC
@4SO
GGGAGACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTT
+
@CCFFFFFHHHHHIJHIIJJJJJIJJIIJIJJJIJJJJJJJJJJJHHHFFFDDDDDDDDDEEDDDDDDDCDDDDDDDDDDDDDDDDDDDDDDDDDDEDDED
@4SP
CACCACAGTTAGCAGAGCGGCCAGCCAAAGCGTTCCCCCTCCACTGAGGATTAACCAGGACCCCAGAAATTTAGCAGACCACTCAGAAGTTCCTTGCTATC
+
;5(=93(28).):@6)()(2((((--.))0=((7(0=19941))/)8)(..).:.<6((.(6(95(,(,((((,83,(((++(385//(5(5(+((+5((5
@4SQ
TGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGAC
+
<@@FDD@ADFFDDB1EAFFFBHAHB<FFDCGIBADH=27CFECC@G>7=AAA=CHCBFBD;>AABCC?BB::A@CBBCB?<AA>C@@>:4:@3<<:::ACC
@4SR
CCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTAT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJIJJJJJIJHHHFFFFFEEEDEDDDEDDDDDDDDDDDDDDDDDDEDDDDDDDDDDDDDD
@4SS
GACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCC
+
@<;AD8AD8=AF:CFECG<,A@CEFE@B):?68949B67(8CFE2@F37)7.).7.).7)?B>6>AA336;-;;(5;;:(5,8ABBB3((+8(08>:+++
@4ST
CAACAGCTCACTGCAGCCTTCACCTCCCATGCCCCAGCAGTCCTCCCACCTCAGTCTTCCAAGTAGCTGAGACCACAGACCGCAGGATGGAAACAAGCCC
+
@@@DDDEFHDHFFGIIGIJJIIJJDGDHIEFIIIEIEGHEBFGHGGIIIIEEHCHIIAHHIIG@EDDCGHFHEBCEF>CCDBDDDDDDDBCCDCCBABDD
@4SU
CTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGC
+
?@<DDDFFFHGHGJHIJJJEIJEGIIJFGGIIJIIFHHEIJFIIIGHIIBHGIIIGGGEGIJJJJEFFHFFF@BCCECECEEDDDBBBDACCCCBDDDD@
@4SV
CACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAAT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJHIIJJJJIJJJJJJJJJGJJIJHIJIJJJJIJJJJHHFFDDEDEDDDDDDDDDDDDDDDCDDDDCCDDDDDDDDD
@4SW
GGGAAGACCTGGCTTACATGAACCACATCATGCTCTCTGTCTCCCCGCCTGAAGAGCACGCCATGCCCATTGGGAGAATAGCAGATGTGAAGCACATTA
+
+8814AD:A<+<;EEEIB?4+A<FE=9+:91**:1DDIIIA90*:8)?A;BDI3867;A//;/5;9).(6;;;(;(,;>(::A:9((,((,4>><>A34
@4SX
CCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCT
+
@@@BDDDAF>?DHBEIIG@HHHGGGEGFHIAGEGIIIIGCFH>GHHDHGECGGIIIGECAEEHIDGH>?ACEBE?CCC>@ACACCBBCCCBCCCBBCBBC
@4SY
TACCTTCTGCTGGTGGGCATGGTAGGAAGGCATGTAGGAGATGTCAGAAGGGTACTTGTACATGGACGACTCGGTCGGATGTGGCTGCAGAGCCTGGGC
+
C@CFFFFFHHHHHAFHIGIJJJDHHJGGIJIJJIFIJJGJEIGIIIHIGIJI.=FHHIFHIICHIIJHGFDDDDABDDDBD>CDDBDDCC:AABCBDDD
@4SZ
TATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCT
+
@?@?DBDDAF?FFG>GAFHBBCEF?EHHHIIDB9@FHH@F@*9?DGGHHFGI9FGFH==DAE6AA>>?7;??>A=;>-;;A:A>8=@=?<<<A@CC:>9>
@4T0
GGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATAC
+
<@@BDDDDBHDHAHDE<CED@H@HF?DHGGIIIGGGII=FHIIIGGFGGIIIIDHI<GCGGB4=9C;@ACCCCCCCCCCCCCCBBBAAB??BACBCCCCEC
@4T1
CGAAACCTGACCGGGCCTTCCCAGCTCACCTCCCTCCATCGCAGTCCATACCAGATAGCAGCTACCCCATGGACCACAGATTTCGCCGCCAGCTTTCTGA
+
@?@DDFFDHHBBHEH>EGGHIBDGCDGGHIGEGIGGIICHHHI@FFA7@EHGEE;=CDFFFDEEEC@ABCCCCCC@BBBCCCC>?BCBBBBBBCCCCCC@
@4T2
CTGATGTCAGCTATACCCAGGCTCAGACCTCTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACT
+
=??D;DB,=?DCDC<EBEE=FFID+<C@;EBEIID>CDAE>B@DDIDIIDDA8@DCDD>;=CD?DD3?DAA@A1;=A??<>>9:<:>A>AAA>AAAAAAA>
@4T3
CTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTAT
+
CCCFFFFFHHHHHJJJIJIJJJJJJJJJJJJJJIJJJJJJJFHIJJJJJJJHCEHHHFFFFFFEEEEDDDDDDDDDDDFDDDDDDDDDDDDDDDDDDDCDD
@4T4
CTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTAC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJHIJJJJJJJJJJJJJJJJHHHHHHFFFFFFDEEEEDDEDDDDEDDEDDDDDDDCCDDDDDDBDDBDD
@4T5
CCTACAAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGT
+
@@@FFFFFHF>DFIJJIIJGIGGGJGHJGHIIJIJJGIIJEGDEHIGIFGEEHIEACHHIIJGEGIGDECEEEFDDAC?DD@C@?CCAACCDDDDDD?@
@4T6
CAGCTTTCTGAACCCTGTAACTCCTTTCCTCCTTTGCCGACGATGCCAAGGGAAGGACGTCCTATGTACCAACGCCAGATGTCTGAGCCAAACATCCCCTT
+
C@BDFFFFGHHGGIHJIJIIIIIJIJJIJIJJJJJJJJJIIJJJJJIIJJJJJJJIFHHHFFFDEEDEEEDDDDDDDD?CCCCDDDDCDDCDDDDDDDDDD
@4T7
CTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGT
+
?81==2==D32<2<<EA<:CFI?F<F;F@):8)00?BDIDI??D*9D8B9D?C<=BC>47...7@3@;.?7.??;7(..,'3;252((,,5>A4((+++(+
@4T8
TGGTTATCGAGGAAAGGACTGTAGAGCTAATGTTTACCTTCTTCCGACCGGGGAAATAGTTTATTTCATTGCATCAGTAGTAGTACTATTTAATTATGAGG
+
BCCDFFFFHHGHHJJJJJJJJHIIGIJJJJJJIJJJJJJJJJJJJJJJIJJJHDFFDEECEEDDDEEEEEDDDEDDD@CDCFDDDEEEEEEEEDEEECDDD
@4T9
CCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTCCATATGGCACTC
+
?1=B7BD3DD?CDD>E<1<C<CEE3CEBBC@DEI<49?<0?D6B8DCCA498=BC4.=3=(6=;AA?7=1.;?;;;;3;>>AAA>>>>(5>:;A;:<,:<A
@4TA
GGCTTACATGAACCACATCATGGTCTCTGTCTCCCCGCCTGAAGAGCACGCCATGCCCATTGGGAGAATAGCAGACTGTAGACTGCTTTGGGATTACGTCT
+
@@@DFEFFDDDHHIJJJJCECGDFHHIJBFHDHHCHIGGEHGFHGEHC>GIJAHGJJJ<DCCEAHEDFFC>CECAB3(5;AACC@CCCC>ADBC>@C@AB?
@4TB
GATAAAGTTAATGAATGTGGCAATAAATGAACTGAATATAAAATTGCAAGATACTAACTCTCAAAAGGAAAAACTCAAGGAAGAACTAGGACTAATTTT
+
@@@FFBEDFHDHHGIIICIHHHHGHGCDEAEHGGIJIAHGJI@FGGGIGA;BFF@GGGF<FFFHGGC;BFHIIEC@=EHHHHEDFB@D>CA@;?CDADD
@4TC
GGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCA
+
@@@FFFFFHHDHHIIIEHJJGGIJJIIIIJCGIJJIIIIJIJIIGIG?FDFGIIJJGJJJGIGGIIEEHHGHFFFFFFEEEECDDDDDDDDDBDDDCD@C
@4TD
CTCACCTCTCAGACAACTAAGACAGATGACCCCCAATTGAAAAGAGAAATAAGGTTAATGAAAAACAGAGAAGCTGCTCGAGAATGTCGCAGAAAGAAGA
+
@@@FDFFFHHGHHJJJHHIGHGHHIEHIIJEIJJJDHIGIEGHHJJJIGEHJJICHGIHGIJCGHAEHAEEFFFFFFCCD??BDCC>A??BBBDDACBCC
@4TE
GGAATTTAAACTGATTGAGCCTGAAGAGGTGGCCCGACGTTGGGGCATTCAGAAAAACAGGCCAGCTATGAACTATGATAAACTTAGCCGTTCACTCCGCT
+
C@CFFFFFGHFFHFHHIIGGGIIFIJHGIHHI<ECFGHHHIIEGGGAGHGHJGFHHHDEEFDDDDBDDCCDDDDACDCDEDDACCDDCCDBDCDDDDDBDB
@4TF
GTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGC
+
C@@FFFFFHHHHHJJJJJJJJIJJJGIIJJJJJJJJJJJJJJJJJJJJJIJIHHHHHF@DFFFEDEEEEDEDDDDDDD>CCDDDDDDDDDDDDDDDDDD
@4TG
CTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCT
+
=>+2??<A=C=<ACBBCBBB=>A):;??7?ABBAA8<B>9=A>3=A==ABBA>>;>>A@@@=@2;;>@55;;=??3;==:====;<9;;;;;=?=?;=:?3
@4TH
GTTTTGGCTGTGGAGTTTCACCCAACAGATGCAAATACCATAATTACATGCGGTAAATCTCATATTTTCTTCTGGACCTGGAGCGGCAATTCACTAACA
+
C@CFFFFFHHHHHJJGHJJIJJJJJJJJJJJIJJJJJIJJJJJJJJJJJIIJJIIJJJCHIJJJJJJJJHHHHHHFFFFFEEEDDDDDDDDDDDDDDDD
@4TI
CGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCT
+
???=DFFDHFHFFEBHBGIIGIIIIGDADAGHEGGGJFI9BEGEIEEBC<D;FEG8;CGGIIDHGGEHGHHHFDFDDDDDABACCDCC?CDCAA@<ACDDD
@4TJ
CCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGCCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGGCAGGACCACCCCAGT
+
=7:=A077+<++@<+<@A<<3A32A=;A<*?A>7=)0:?A<=*00==3(-=A3AAA2((6))7-:=@==((5(5-;;(5((,('3)030(+((()&9;(
@4TK
GAGAGGGAGACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGT
+
CCCFFFFFHGHHHIJJHIJJJJJJJJJHJIIJJJJJJIJJJIJJHDHHHFEDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDC
@4TL
CTCTGATGGACAGCAGATACTTGTGCCCAGCAATCAGGTGGTCGTACAAACTGCATCAGGAGATATGCAAACATATCAGATCCGAACTACACCTTCAGCT
+
CC@FFFFFGHHHHJJIJJJIJJFHHIIJJJJJJJJJJJHIIFHIGHHHIJJJIJJJIJJIGGGIJIGHGHHFFFFFCEFEDEEDBDDDCDDDDDDCDDDD
@4TM
GTCCAGTTGCTCTGCTGTCTTGTGTTTTTGCAGCCTCTACAACCCCACGTCAGAGGGTGGGATTCTGTTACTCTATCCACACTGCAGATTATTGGACTTGG
+
@???DDBDFFFFDG9FH<:<EIDAAFHIIIEHG<GHEGGIEIIAFFHIIADCFCC(5-;BB;BC>DC;ACCC@CCCCCA>A?5@C>C>@@@CDCC>AC@CC
@4TN
CTTCAAATCAATGAACTTCAAAAAGAAATTGAAATACTCAGACAAGAAGAAAAAGAAAAGGGTACACTTGAACAAGAAGTTCAAGAATTACAACTTAAAAC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJIJJJJIJJJJJJJJJJJ>FHJIJJJJJJJFHGIJJJJHHHHHFFFFDEEEEEEEDDDDDDDDDDDDDC
@4TO
ATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCC
+
@@?ADDDDHHHGHAAACBCGHGGCGGH@*?B>?):DFFG>B6::4FE=CECEHAABCF>BCC>C>6',828?B?2?@B<?CA>?AAAAC@>ACDB?<A?B
@4TP
GGGAGACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTT
+
@CCDFFFFHHHHHIJJJJJJJJIHIJGIJJJJJIJJJJJJJIJJJHHHFFFDDDDDDDDDEEDDDDDDEDDDDDDDDCDDDDDDDDDDDDDDDDDDCCCED
@4TQ
CTCCGTTATTACTATGATAAAAACATTCTGCCTAAAGTGCTCGGAAAAAGTTATGCTTACAAATTTGACTTCCACGGCATTGCCCAGGCTCTGCAGCCAC
+
===<;+<277@B@,<,?,,3<+@@3+?+2<<<*?>7*11?*11))849A0*=4>4<)>).===>8)77.)).7)7-/''3(5((--,(52,,:(9>?=;<
@4TR
CGACATGTGAATATCCTACTCTTCATGGGCTATTCCACAAAGCCACAACTGGCTATTGTTACCCAGTGGTGTGAGGGCTCCAGCTTGTATCACCATCTCC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHIDHHHHHHHFFFDDEEEDDDDEFEDDDDDDDD
@4TS
CATCCAGTCACGGGAGCCCTCCCTGAAGAATTCCAACCCCGACGAGATTGAAATCGACTTTGAGACCCTGAAGCCGTCCACACTGCGTGAGCTGGAGCGCT
+
@<?DDD8AA?D<@CFEBGGEEFFGFI@BD?GDDDGFFFAADF@A@B8??A??;?@@69??B@;??:?9???B:A?@BB<?BA@?B:<<9BBBABB@BB@B?
@4TT
CGGCGGGGAAGATGTTCAGCGTAGAGTCGCTGGAGCGGGCGGAGCTGTGCGAGAGCCTCCTCACTTGGGTCCAGACATTTAATGGGGATGCACCATGCC
+
>==AAAAA4=;=>>8A=AABA(;:;=7>6939=(;;7==&07&05(3++(0&0)0(838;38(88;8;(28;?38;9:??7;88(29(&2(+8=2383:
@4TU
AGCTGAGAAAGTTGATGTGATTGCCGGCTCCTCCAAGATGAAGGGCTTCTCGTCCTCAGAGTCGGAGAGCTCCAGTGAGTCCAGCTCCTCTGACAGCGA
+
CCCFFFFFGFHFFGDHHGHJIJJIHGIIIGIIJIIJJJJJJJHJIIIGGIJEGGIIGIIGG?AHFFDACDDCCDCDDCCCCDDDDCDDCDDCDDDDDDB
@4TV
CCTCCTAAAAAGACGAAGAAAAATAATAGCAGCAACAGCAATGTGAGCAAGAAGGAGCCAGCGCCCATGAAGAGCAAGCCCCCTCCCACGTATGAGTCGGG
+
=+122<A4?=AAABA01@CCBBB;B@?7*:?*??AA):=>B73=A9?BA9=BBABB==53=<A=@@@@>>5;(5;>:9=====-9;0(20++3983+809&
@4TW
CAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGC
+
=??D4ABDDD?:DEA:C@CEDA?BC@FBEAE1:D?D:B9BDDCDDD?DEIID=38B@A@CD>AC@C>D@;CA>AD@;(6;9333,:;>>>5>:>DA4>A
@4TX
GAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACC
+
C@CFFB??F@FHHGIIIIIIIIIGGIIIIIIIBDHIIHIIIIGGBGGBGEHGGGHFEEFF>AAECCECCCCCCCBBBBCBCBCCCCCBCCCCCDCCCCBC
@4TY
AGATGGGGATGGGCGGCTTCGGCCCTCACCTGGGCTTCAGGGGGCTGGGGGCGCCGCTTGCCTTGGAAAGGTTTCTTCTTCAGGAAAACGGGCAAGAGA
+
@?@?BADBAFBFHIEGIGAGGEIIIBEIAGAHGIFHHA;BBECBBBBBB@@BB88@8<B@BCCACC>@ABBCCCCC>CCC:A>@CBC?ABBBB9@BCBA
@4TZ
ATTACCTGGCTCACTAACTAACGTGAAAGCCTTACAGAAATCTCCAGGACCTCAGCGAGAAAGGAAGTCATCTTCATCCTCAGAAGACAGGAATCGAATG
+
?@<DDDDDBHDFDHB<CGEADGGAEFEBC?F9:FFABBHGCGGGGGGG8BF@DD@FA8@@@DHH>A?.;BE>>;;>6>CACCACFCA?CC?(9A@9<:AC
@4U0
CCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCTGAAGCCAGCAGCCACT
+
===AAAAA87?+,+2@B9+<=ACA17?=A7@AABA7?77A:<AB4=*<?ABAA*>7)=A>A3)>B>BBA;)=A)..=>7;>(.;(9(-5=259==229=<:
@4U1
TTCTCCTCTTAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGAC
+
CC@FFFFFHFHHGJIGIJGIGIGHGGGGJIJIGGEFHIDHJEGGEHHGIIIJIJJJGGIJHGHEHDFFD=BBACDCDBAB@BBBDDCCDCDDCDDDDD
@4U2
TTCGAAACTGATATAGTACAACGAATGGAACAAGAAACACAAAGAAAGTTAGAACAACTCCGGGCAGAGCTGGATGAGATGTATGGGCAGCAGATAGTGC
+
CCCFFFFFHHHHHJJJGHIIIGGIIJJJJJIJJJJJJJJIJJJIJJJJEHIJJJJJJJJJJJIIHFFDFCEEEBDDDDCDDCDDEDDDDDDDDDCDDCDC
@4U3
TGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTC
+
B@@FFFFFHGHHHJIJGIIJIIGHGHJJJJJJJJIJJJJJJJIJJJJJIJJIJJJIIJJIIJJJJJJJHGGFFFDDDDDEEEDDEDEDDDCDDCDDDDDDD
@4U4
CAATCATTGAAGAATTAAACACAAAAATAATAGAAGAAGAAAAGAAAACTCTTGAGCTAAAGGATAAATTAACAACTGCTGATAAATTACTAGGAGAATT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJIJJIJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJIJHHHHHFFFFFFEEDEEDEEDDDDDDD
@4U5
AAAGCATTCGCCCGGTGGCACCTATCCCAGAGTCCAGACACAGAAACTCTTTCCTGTTTTCTTATCCCCGTGCTTCGTTCCCTGGCCCGGGTGGAGCCAAC
+
(((<>)):).(((<(-<(=)=?;3)))).:(.>).))<=?1>())).9)))/))/))8=?31)).)))(,','7=>5(((75,((7(,))&&))+22(((+
@4U6
TTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAAC
+
@@@FFFFFFHHGHJIJJJJIIJJJJIJJJJIGEHIIIJFGIJ@GDIIJJIGIIIJHHEFBFDBEEEDDDDCCCCDEDDCDDDDDDDDDDDDDDCDDDDDDD
@4U7
CATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACT
+
CCCFFFFFHFHHHJJJJJJJJIHIJJJIIIIHIJJJJJJJJJHIIIIIJJJJIIJJJJJIIJJJJJJJHHGHDFDFFEEEEEDDDDDDDDDDDBDDDDDCC
@4U8
AACCTCCTCCTAAAAAGACGAAGAAAAATAATAGCAGCAACAGCAATGTGAGCAAGAAGGAGCCAGCGCCCATGAAGAGCAAGCCCCCTCCCACGTATG
+
==@DDD;DBFFDAEFEGGHG<GDF@CBF?DHGIGBHCHGB@B?(??8=FC@CEDG@@G@6==EHEAD9AC>?CCCC@C<<A<5<?A@99><89252<>?
@4U9
TCCAGCGACAGCAGCAGCGATAGCTCCTCGGACAGTGACAGTTCGACTGATGACTCTGAGGAGGAGCGAGCCCAGCGGCTGGCTGAGCTCCAGGAGCAGCT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJGIIJIJIJJJJJJHHHHHHFFFFFFDEDDDDDDDDDDDDDDDDDDDDDCDBDDCDDDDDBBDDDDD
@4UA
GGGAAAGACAGAAAAATAATTCTGTGGGATCATGATCTGAATCCTGAAAGAGAAATAGAGGTTCCTGATCAGTATGGCACAATCAGAGCTGTAGCAGAAGG
+
??@DDDD8D>B;?BGAFHHH9HGE3<CEC3?8C9DA@FHIGI9??9FGHBD;@9DBF=F=C=FG@FH@@EHHGI@E>CH<;;;)7@A@;@A>>@ACC;:>B
@4UB
CAGAGACCTTCTCCCTTTATTCCAGCTGTCTAACTGACAAGACCTTTCTCTCTTTCTTTCTGCCTCATGCTCTCTCCAACAGGCTTGCAGCCAATTTACTG
+
CCCFFFFFGHHHHJJJJJIIIIIIGGIIHIIJJIGIIHIJGDHIIJJJJJJEHHJJGJIJI@CAFHJJBCAGGDEGIJHHGHFFFFDDECCBACCDDCEDC
@4UC
GCAAAAGCCCACTGACGCTCCACCGAAAGATGATTTTTGGATACCAGAAACAAGTTTCATACTTACTATTATAGTTGGAATATTTCTGGTTTTTACAATCC
+
???ADFDEDFHHDGH@GGHGIIDHHGIGG;FGHGGIIGEBDGBGDHEHGIIFHHDEIHFAEHHHBCFFFED@@CBCCC;>CCDD>3(:(5((,((,>:>?C
@4UD
ATTGAATCCCTTTTTGATCATATCTACACCACGCAAAGTGATGTATGGTCTTTTGGTGTCCTGCTGTGGGAGATCGTGACCCTAGGGGGAAACCCCTATCC
+
CCCFFFFFDHHHHJJJGHIJJIJJJJIJJIJJIJIJII?FHIIIJJJIGIHIFIJIIIIJJJJIIJGGFFHFDEFDCECDDDDDDDDDBDDDDBDDDDCDD
@4UE
AGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACT
+
CCCFFFFFHHHHHJJJIJJJJJJJJJIJJJJJJJIJJJJJJJJJJJJHIJJIIJJIJJJJJIIHHEEHFFFFFAEDDEDDDDDDDDDDDDBDDCDDDDD
@4UF
CAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTAC
+
BC@FFFFFGFHHHJJJJJJJIIIEIGHJGIJJJJJJJJJIJJJIIIIIJIJIJJHHHHFFFFFDEEDE@CDCDCDDDDDDDDDDDDDDDCCCDDBDD@DDD
@4UG
CGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACCCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTT
+
?+1B?D;??>D8DDC::E@?A:C++22<CAE;E;:8:9D*??4BD)00?B6B8BC8BA<5A(6;).6;.(6=5?;,5,(,(,585))(:<<A39>8>9::A
@4UH
CCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTTATGGG
+
CCCFFFFFHHHHHJJJJJJHHJJJJIJJJJJJJJJJJJJJJJJJJJIJJJJJJFIIIJHGIHHHHHHFFDDDDDDDDDDDDDCDDCDEDDD9@BDDDDDDD
@4UI
AACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACC
+
CCCFFFFFHHHHHJJJJJJJJJJIJJJJJJJJJJJJJJJJJIJIHGIIJJJJJHHHHFFFFEDEEEDDDDDDDDDDDDDDDEDDDDEDDEDDDDDDDCDDD
@4UJ
ATGAGGAGAAGCGGCAGCTCAGCTTGGACATCAACAAGCTCCCCGGCGAGAAGCTGGGCCGCGTGGTGCACATCATCCAGTCACGGGAGCCCTCCCTGA
+
=1=A2+++22A=<)===1:@@;37?B1?77A>BB;00>B*=>AA6A:9=6;=;3;9(5;9;7;&))88;=:??;8;8=8?=8::5;5;;3;<;<<9<?;
@4UK
CAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAAC
+
CC@FFFFFHHHHHJJJJJJJJJJIIIJJJIJJJJJJJJJJIJJJIJIEHIJJJJJJJJJJJJJJHHFHHFFFFFFEEEEEEEDDDDDDDDDDDDDDDDDDD
@4UL
GGAGAATATATTAAAATGTTTATGCGCGGTCGGCCAATTACCATGTTCATTCCTTCCGATGTTGACAACTATGATGACATCAGAACGGAACTGCCTCCTT
+
CCCFFFFFHHHHHIGGAFIIGGHJJJGGHHJIJJIGJIIJJIGIIDHGHIHIGIJJJHEHFBEFDEDCDEECCCDCDCCDDDDDDDDBDDDCCDCDDDDD
@4UM
GTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTAC
+
C@CFFFFFHHHGHJJIJIJGIIIIJJIIIGIJIJIGIJJJJJJGIIIJJJJJII=CGHIIIJGJJIHHHHHFFFFEEDDEDDDDDDDDDDDDDDDDDDDDD
@4UN
GGAGAGAGATATGTCTACAAGTTTGTGTGTGATCCAGAAGCCCTTTTCTCCATGGCCTTTCCAGATAATCAGCGTCCACTGCTGAAGACAGACATGGAACG
+
CCCFFFFFHHHHHJJJJJJJJJJJJIJHIFIJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJIIJIJJJJJHHHFFFFFEDECEEDDDDDDDDDCDDDD
@4UO
CAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGACACTGCACCTCC
+
8=@7DADDAFFHF>GGFGDGGEHIAHG@FIEGGEHGGII;BFH9=FGHDHGCCHCCEF15).;?AA;A=19=>A?BB<9AA@A@?BB(8(<3>@A@?CBC
@4UP
AGATGACCCCCAATTGAAAAGAGAAATAAGGTTAATGAAAAACAGAGAAGCTGCTCGAGAATGTCGCAGAAAGAAGAAAGAATATGTGAAATGCCTGGAA
+
?@?BDD?DB;CDHBE?CFD@A1CF@F>FCCBDE9?9:?FDGG6BFG>9DGH=FHGHEA8CB@@?EA9=?A>C;;;5;?CC>9>A>C55>AC:>>CCCB?C
@4UQ
CTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCT
+
?<@FDDDAFFBBHEBFEHFHIIGGGCHFD9D?@@A7@GI>B@FG>C77@EHGC=EAHA??@?B;CECC@AC;-;>CCCABAAB=@<?A<@BA<CC@CC@>C
@4UR
GTGCTTCCTCAAGGGAAGGAGCCTTTAGCAGTGCCCTGGGAAGGCTCTTCAGGAGCCATGTGGGGAGATGACAGAGGTACCCCCATGGCTCAGAGTTATG
+
?@@FFFFFHHHFDGIIIJJJJJJJJJIIJJIBFHIJEHJJIIDHIIGGIGGIIIGCGGHIHIGGFEFC@CEDEDCCDCCDDDDDDCDD@<C@CACCDDED
@4US
CTTTTATTCAGGGGATTTGAAATAACAAGCCTCTTTCTAAAAAAGCTTTTTTTTTTTTTTCTCTTCTCTCTCTTTCAGCTATTCCCCTACCAAACCGACT
+
@@@FFDFBDFDHHDGIJIJEHHGIIHIEH@?BFCHHIJIJGJII@FCCDGGGGHFDDBD;333+>4(4:34>:@:(::3(4>@CC(3((+((+(2<9&&&
@4UT
GAAAAACCACAAGGACAGAGAGAAAAAAAAGAGGAATCTCATTCTAATGATCAAAGTCCACAAATTCGAGCATCACCTTCTCCCCAGCCCTCTTCACAACC
+
@@@?B>DBFBHD??EHIIGCFF=B??BGGGIIIE9CFFAGAGIIGIIGGHGHHFHE=@>@BBDC@A>ADABBCCCC?AC?@CCA>CB@?BCBC>>>CAC<?
@4UU
TGAGAACTCTACATAGTGGAGAAATAACCAGTCATGAGCAGGACTTCTCTGTGGAACTGGAAAGTGAAATTTCAACCACAGCAGATGACTGCAGTTCAG
+
CCCFFFFFHHHHHIJJFHGJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJI9BGHIJIJIIJJIFGHIJJIIJJJJHHGHFFFEEEEEEEEDDDDDDED
@4UV
AAAGAAAAAAGAAAAGCACAAAAGGAAAGAGGAAGTGGAAGAGAATAAAAAAAGCAAAGCCAAGGAACCTCCTCCTAAAAAGACGAAGAAAAATAATAGC
+
@CCFFFFFHHGHGJJGJJIJJJJJJJJIJJJIIIIBFGGGIIIIIIJJJJJJHHDFFFFEEEEDDDDDDDCDDDDDDDDDDDDDDDDDDDDDDBCDCDDD
@4UW
CTCACCTCTCAGACAACTAAGACAGATGACCCCCAATTGAAAAGAGAAATAAGGTTAATGAAAAACAGAGAAGCTGCTCGAGAATGTCGCAGAAAGAAGA
+
C@CDFDEDHFHHHGIIGHGGIEEHHJHJJGIEHGGDDGGFIEHGEBDFBHFGGIHGGGIHDEHIJIJHFHGEFFD@DACC?BD@CC>C<ABBBCDCDDCC
@4UX
GTTCATTCCTTCCGATGTTGACAACTATGATGACATCAGAACGGAACTGCCTCCTGAGAAGCTCAAACTGGAGTGGGCATATGGTTATCGAGGAAAGGACT
+
C@CFFFFFHHHHHIIJJJJJJJJJJJJJJJIJIJIJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJHHHEH@DFFDEEEEEDCCDDDDDDDDDDDDDDD
@4UY
CTGCCACTCCATTTATATGAGGCAAGAAGGCTTCCTGGCTCATCCCAGCAGAACAGAAGGCTGTATGTTTGAAAAGGGCCCCAGGCAGTTTTATGATGAC
+
CCCFFFFFHGGGHJJIIJJJJJJJJJJJIGHIIJJGJIJJIJJJJJIJJHJHIDIHIGDGGJJEHIIJIGHHHHHGFFFDDDDDDDDDCDEDDDDDDDED
@4UZ
GGAAAATTCAGATGATAGCCGTAATAAATTGTCGAAAATACCTTCAACACCCAAATTAATACCAAAAGTTACCAAAACTGCAGACAAGCATAAAGATGTC
+
CCCFFFFFHHHHHIJJJJIIIIIJJIJIJJJHIJJJJJJJIJJJIJJIIJJGIJJJJJJJJJIJJJHGEHHHFFFFFECEEEEDDDDDDDCDDDCDDDAC
@4V0
GCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAG
+
@@@DDBDFDFHDHGGGIIIJEIIGGEEHEHJJGGIGGGEGGIEHEHHHGGGHGIEIGGJFACHHFFDD;;A@CCCBBDBDDDDBD?CDDCCDACCCDCD
@4V1
TAAAAATCCATACAGCTTTCAGTCAGATGTATATGCATTTGGAATTGTTCTGTATGAATTGATGACTGGACAGTTACCTTATTCAAACATCAACAACAGGG
+
@@@FDFFFFHHFDIIIIHIIIGHD>@HGEFGHHGIIGIGGIIIFHEEDFGDG@DDHGIIDGIGBCGCBF>=FFHEGEHCHGIIIGDHFAC@DFFCB;AEDB
@4V2
TCAGAACCCTCCTTGAATCGGGCTGGTTTCCAAACAGAGGATTTTAGTCTATATGCTTGTGCTTCTCCAAAAACACCCATCCAGGCAGGGGGATATGGTGC
+
@@@FAEFFGHHHGJIIFGIIJJIJJJCGGGHGGIGGHHGIHDHHIGJHHIE=CEG;@FH;DEHI@EFHHHHBFE;ADDDDDDDDD<(<@DBDDBACDD>C3
@4V3
AGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACC
+
CC@FFFFFFFHFFGHGIIIGGIIJIHGJJIIGGFGGHIIJIEHIGIEGGIGIEEEEDDDDCFCCECEDDDCDDDDDBDDBA?ACDDDDDDDDACDDDDD@?
@4V4
CAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCT
+
???BDDDA;CDB3E?E?+AF:C22A?)?;E>8DDAE>DAD>DDII>6;BBCCCECECCCDE===;=;???66>AAA55-;555;>A98=25,,5<>>??>
@4V5
GAACACCTCATTAGGTGTCTACGGTTAGAAATGGTTGGTATCAGGGTTTCTGGACTGTGCGAGCCAACAGAGCCCTGCCGGGGTTTGGGAAGATTTCTATT
+
-(((22(2()2.)299));:@=(32(=3>3=).)))-(-)0:))0()(-<<>;)=96.6)'5''').,7=5(:=3;;;823'&&&+22&+((++((+(+(+
@4V6
CTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTT
+
CCCFFFFFHHHHHJIJJHHIJJGIJIJIJJJIJJIIIJIGJJJJFIIJIHIIJJJIJJJJJJJJJJIHHGHFFFFDDDEEEEDDD:@CCCBDDDDDDDDDE
@4V7
ATGAGAAGAGGACCCAAAAAGCAATTGGAGATCATGCGTGTGTTTCTGCTGTTACAATCAGTCAGTCCTATAGACTGATGTATCTTCGAGGCCCGGATTTG
+
75-(()6)1.:((2(((2.;8(97>3;9?<>?))1:)-((0.0)))0.)9=)38=<3;)9)).6..:.:)..)).)).6(.((.(((,((',,()))))4:
@4V8
CTAGAGGGAAAGCGAGAGGGAGACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGC
+
?@@ADDDDDDHFHI7FHIGHG@:?DE<DDF?BGEHGIIEGBHFBCDE?BCC@5=?CCCCCCBBBBBBCBBB@BCCCCCD@CCCCC>@>C?@BCCCCCCBB
@4V9
GCCAAAGATGATTATCGAATACGTTGTGAAGAGTTAGAAAAGGAGATCTCTGAACTTCGGCAACAGAATGATGAACTGACCACTTTGGCAGATGAAGCTC
+
@@@DFFF>FDADFBFAHGHIHIG?FB<CAE9CF:?CFHIII;BGHB?DBFBGIIEHIIGGIHEIDCEHFGA7?CDFDFCEE>A;@CCCCCB1:>CCCCCA
@4VA
GGCGCCTTTGGGGAGGTGTATGAAGGCCAGGTGTCCGGAATGCCCAACGACCCAAGCCCCCTGCAAGTGGCTGTGAAGACGCTGCCTGAAGTGTGCTCTG
+
CCCFFFFFHHHHHDHICGEGGGJIJJIJIIGFHHIIIIGIJJJJIJJJIJFHFFEDDDDDDBDBCCDCCCDDDBCCDDCC>B@>BDCCDDDCD:@CDDCC
@4VB
GTTTATTTCATTGCATCAGTAGTAGTACTATTTAATTATGAGGAGAGAACTCAGCGACACTACCTGGGCCATACAGACTGTGTGAAATGCCTTGCTATAC
+
BB@FFFFFHHHHHJJJJJJJGJIJJIIIJJJJJJJJJJJJIJJJIHIIIIIJJIJJIJJJJJIIJJJJJHHHHHFFFFFEEECEEEDDDDDDDDDDEEED
@4VC
CCTGATGGGCAGATTACAGTGGGACAAAGAATTGGATCTGGATCATTTGGAACAGTCTACAAGGGAAAGTGGCATGGTGATGTGGCAGTGAAAATGTTGA
+
??@DDBDBDF>FAG<EAHBACE=DCAHGE;CD<BG9??<FEG?FB?9D@FHEHIG8=BG:FHIIGGEED)=CEEEEE;;66@;@@9=?(;;ACC3:,;@:
@4VD
CTGGGAGATCTTCACCTATGGAAAGCAGCCATGGTTCCAACTCTCAAACACGGAGGTCATTGAGTGCATTACCCAAGGTCGTGTTTTGGAGCGGCCCCG
+
???;1A1=D?CDD>+A3<E>FCEECFFF3?EE9E<?9*:?3;BDEDED9?D:@AAA1==;@CCA?CD@?;@A@DD@@<6;9;;9<=?2'5=?9?;95>;
@4VE
CCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGT
+
@@CFFFFFHHHHHJJJJFGJEGFHIIIHGIIJGIIJJJJIJGIJJJIIJIIJHHHFHGFFFECFCEEEEDCDD@CDDDDBD??BDCDDDDDCCCCDDDDB@
@4VF
GTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCC
+
@@@DDDDDF<:C?AA?;@CECBDFEHHGEHG@BGGG?<DFHIIB@DI@FH>A;DCH>GHFFFEEA>@@1?B;>=@??BC@>AC@A:ACC>:?:>9?>AA28
@4VG
CAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGG
+
CCCFFFFFHHHHHJJJJJJJJIJJJJJJJJJJHIJJJJJJJJJJJJJJJJJJJJJJJIJJJJHHHEFFFFFAEDEEEEEDDDDDDDDDDDDDDDDDDDDDD
@4VH
CACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJIHIJJJJJJIJGHFFDDEDDDDDDDDDDDDDDDDEDDDDDDDDDDDDDDDDDDE
@4VI
GCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGC
+
CCCFFFFDHHHHHJJIJJJJJJJJJJJJJJJIJJJIJJJJJJJJJJJJJJJJIJJJJJJJJJHHHHHHFFFFEEDDEDDDDDCDDDEECECDDDDDDDDDD
@4VJ
GTTTTGGCTGTGGAGTTTCACCCAACAGATGCAAATACCATAATTACATGCGGTAAATCTCATATTTTCTTCTGGACCTGGAGCGGCAATTCACTAACA
+
=+?B?AD;FDFFDIB<?GDEFI@BBCGFGEFFIFAD>GFCEFIEBFBFBDCEIAFFG>FDECEECFE@AEFEEFBDBDDDC>>@@BB6?BB>:AA@>AB
@4VK
CGAGTCAGCTGCGCGGGCCCCCGGATCCCCCGACAGAGCGGCGGCGGTGTCTGGCCAGGCGGTAGGCGCTGCCTGGCCGCGGCGGGGGAGATGTTCAGCGG
+
CCCFFFFFGHHHHJJJJJJJJJJJJJHHHHFDDDDDDDDDDDDDBBD557@ACDABCBD?BD7@BB>75059A:>A<B999@59>BD0)))((+:((+()&
@4VL
CAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGAC
+
CC@FDDFFHD?FBHIGGBEGHGJGGGEGHIGEFF?GFCGIGDHIIGHBBFAGBDGIJGIGHIIIGIGGDC@CEC<B@AA:@BDDDDDCDDDDDC>C@AAC
@4VM
ATTATGACCAAAGTGCACGGCAAAAGATATGCTTACAAATTTGACTTCCACGGCATTGCCCAGGCTCTGCAGCCACATCCGACCGAGTCGTCCATGTACA
+
CCCFFFFFHHHHHHIJJJJJJJJIJJJJIJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJHHHDFFFFFEEDEDDDDDD@DDDDDBDDDDDDEDEEED
@4VN
GATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTAGGGGCAGCAGCCTCC
+
??<?D>?D?DFAD@FB<?+AD<FDDC;CGG@@4CFE??C?BDADG6BBC9.>87=7C(=D9A7)=AA;BC@.;>@CCA6(5(((5:(5<@?=9?@B1239<
@4VO
CATTTTATTGCCTGGACTGGTCGAGGCATGGAATTTAAACTGATTGAGCCTGAAGAGGTGGCCCGACGTTGGGGCATTCAGAAAAACAGGCCAGCTATGA
+
CCCFFFFFHHHHHJIIJJJJHJIGIIJJJJJJJJIJJJIJJJIJIGJIJJJJJJIDIIGGGIIGFDDDDDBDDDCDDDDEDDDDDDDDDDDDDDDDDDDD
@4VP
GTTTCACCCAACAGATGCAAATACCATAATTACATGCGGTAAATCTCATATTTTCTTCTGGACCTGGAGCGGCAATTCACTAACAAGAAAACAGGGAATTT
+
CBCFFFFFHHHHHJJJIJJJJJJJJJIJJJJJJJJJJJJDGIIJJJJJJJJJJJJJJJJJJJJJJIJJIIHFFDDDDDDDDDDDDDDDDDDDDDDDDDDDD
@4VQ
CACGTTTGAAATGAATGGCAAAGCTCTCCTGCTGCTGACCAAAGAGGACTTTCGCTATCGATCTCCTCATTCAGGTGATGTGCTCTATGAACTCCTTCAGC
+
BCCFFFFFHHHHHJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJHHHHHFFFFFBDEEECEEEDDDDEDEDDDDDDDDDD
@4VR
TGGAAATGGGGGAGGTTGTTGAAAAGGGTACAACAGAACACATCGAAACACTTGAGGTAACCAAGAGAGAGAAATTAGAGCTGTCACAGAG
+
?<?D;;4BDD+0<<C<EE:)8?DB*?D)0*9@A??;8*)).(8)()8@/@9A3)7=;).7;;36>((;(((,,5(5,5:(:>>+44:(4>>
@4VS
CTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCT
+
?@@DDABDFFHFHHGGGIGIHIGIGFGHGGIJIIIIIIGGIJHFHHIIIIECFEAGIJGJFBEHH@BDFEED@CBBCCDD@@C?CDDBBDDBDDCD?>:?C
@4VT
CTGCAGTTCAGAGGTAAATGGTTGCAGTTTTGTGATGAGAACAGGAAAGCCTACAAATTTATTAAGGGAAGAAGAATTTGGTGTTGATGATTCTTATTCTG
+
CCCFFFFFHHHHHJHGIIJJJGHIJIIIJJJJGHHJIIJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJGJIJJHHGGHHFF@DDDDEDDEFFEDEDDEDFE
@4VU
TGAGGAGAGAACTCAGCGACACTACCTGGGCCATACAGACTGTGTGAAATGCCTTGCTATACATCCTGACAAAATTAGGATTGCAACTGGACAGATAGCTG
+
::+ADDA3<2ADBB<E<8328?9?E>??DD=36??)?B8??89=.8B@DC;4=AE@;C@;A>;=CDD>;77?>6>@;>:5;;>A>;>>AAA?<?>A>>:>>
@4VV
ACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACC
+
CCCFFFFFHHHHHJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJIIJJIJJJJJJJJJIJJIJJJJHHHHHFFFDDDDDDDDDDDDEEEEFDBDDDDDDD
@4VW
GCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGC
+
@@@DFDDDHFDAFIGBHIGIGIJJJJGJGHIGIJJEHGGGHHGGGGGGGCBHHIGJGCAHICGGAEEEHHFFDBBACABDCCDDDDDDCDDDDDD>C@AB
@4VX
AGAAATTGCTCAAAGATGCCATGAACTGGATATGCAGGTTGCAGCATTGCAGGAAGAGAAAAGTAGTTTGTTGGCAGAGAATCAGGTATTAATGGAAAGAC
+
?@???BDFDDB?FHECHBEFIIIGHBHHG?ACHBGGHGICACB?FB9?D9DFHBBFD?=B==C7@C=FFEGHGEEAHCBDFFDC@C66;@>>CCCCCCBCC
@4VY
CAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATAT
+
@@@FFFDDDFHHHJIEBHEG@FGCGFEHGHHJJIEIIJAGHHGIGHEGIHGGEBDHHGAHIJB@EHFFCCFBCFECCEEACBB9??@CCCCD(:@C>CC
@4VZ
TTTGAAAATATGACTGTTGGAGAAGAAAGTAAGCAAGAACAGTTGATTTTGGATCACTTACCATCTGTAACAAAGGAATCATCACTTAGAGCAACTCAACC
+
@CCFDDEFHHHHHIJJIGJJJIIJJJJJJIIJJJJJJJJJJJIIJHIJJJJJJJJHIJJJJJJJJJJHIJIJIIIJHFHFHFFFFFFECDECEDDDDDDDD
@4W0
TCCCCTTCCCACCACAAGGCTTTAAGCAGGAGTACCACGACCCAGTGTATGAACACAATACCATGGTTGGCAGTGCGGCCAGCCAAAGCTTTCCCCCTCCT
+
@@@DDDDBDH<FHBDH;?FC@?E@D@C<FFHC?CF9BF;@FGG=C==/=C.=;=.7@C@@?A>AEDD;?<>;ACC:?@@:=8828ACC3+(+44A9555?C
@4W1
CTAATTCTAAGCAAAAAGAAAGACAGTCTTCTGAAGAAATAAAACAGTTAATGGGGACAGTCGAAGAACTTCAGAAGAGAAATCATAAAGACAGCCAGTTC
+
@B@DDDDFHHFHGJIGIGGGGIJIIJGIIIIJJIIIJJIIHHJIIDIHGEIGGGGGDGHIACHGHAHHCHHFHFFFFDEEEEEEDDCCDCCCDDDDDDC>C
@4W2
CTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTC
+
@@@DFFFDHHHHHJJJEIJEFHGICFIJIJJGJIIIJIHIIEGHDEGIIJJJIJEEHIIJJJJIDGHFEFDADDDDDDDDCCCAB?CD?B:ACACDCDC:@
@4W3
GCAGGGCTTCTCTGTGGAACTGGAAAGTGAAATTTCAACCACAGCAGATGACTGCAGTTCAGAGGTAAATGGTTGCAGTTTTGTGATGAGAACAGGAAAGC
+
CCCFFDFFHHHHHJJIJJJIIIJHIHIFGHJIIJIIIIJJGIJJIJJIIJIJJIHJJHGHIGACD8@ECGIJEEHHHFEFFFDBECDEDDDDDDCDBDDDC
@4W4
CGGTTCATCCTGCTGGAGCTCATGGCGGGGGGGGATCTCAAATCCTTCCACCCACTGCACCCCCCCCCACCCCCCCCGCCCTCCCCCCCCGGCCTAGCGG
+
:+12A;AABB?<@A>>C+=AA==A++?6(-,&&&)&+(++((+(+++(((++&(((+(+388;;=&&&&))&&))00-&05&+229-0&)&&)&)+(()&
@4W5
GAATTATGCAAAAGGTGGCTGGAGAGAGATATGTCTACAAGTTTGTGTGTGATCCAGAAGCCCTTTTCTCCATGGCCTTTCCAGATAATCAGCGTCCACTG
+
@@@FFFFFHHHGHJJFHIIJJJGIIIJJIJJJJIJJJJJJJHIGIGGHHFHJJJJJJJJJIJJJJIIIJJHHHHHFFFFFFEEEECEDDDDCCD?DDDDDD
@4W6
AGGGAAAGCGAGAGGGAGACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGC
+
@@@D?DFFHFFHHIJIBBHIIGIGIDHHIIGIFCFGAGEACECHHFDFDDDCAC>AA=@@D:@DDDBB7CDDCCDCCDCCDDDCDCB?ACD?C><B@BD
@4W7
CAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAAC
+
CCCFFFFFHHHHHJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJIJJJJJJJJJJHHHHHFFFFFFEEEEDEECDDDBDDDDDDDDDDCDDD
@4W8
CAATACTGGACCTCCCCCACGGGGGGAATCTACCCCAACCCCAACGTCCCCCGCCATCCTAACACCCACGTGCCTTCACACTTAGGCAGCTACTACTAGA
+
@CCDFDDDHFFDDIJIHJIJEGGED9B@AC8@CCB<?B?BBBB<<@ABB5A8BBD8<C@CC@?CCDDBBD188ACACCCDDCCC@CDCDDD@CACACDD@
@4W9
CAGAACAGGACTTGATTAGAGACCAAGGATTTCGTGGTGATGGAGGATCAACCACAGGTTTGTCTGCTACCCCCCCTGCCTCATTACCTGGCTCACTAACT
+
@@@FFFFDBDDHHGGIIIEGIFGGIJIICEGEGEDFHGHFHGIGJHCGGIIJJIIGIFIGIGHHGFFHHEFFFDDDD?BBDDCDEDDDDDDBCCDDDCCDD
@4WA
AAAACATTATGACCAAAGTTCACGGCAAAAGATATGCTTACAAATTTGACTTCCACGGCATTGCCCAGGCTCTGCAGCCACATCCGACCGAGTCGTCCATG
+
@@@DDDDDHBFFHIIIGIH,AFEGIIIIGIIIIIHGIIIIIIIGGIIIIIIIIIGIIIGIDIIHHHHHEEDECCCCCCBB@BCCCBBBBBBBBCBBBBBDC
@4WB
GGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTT
+
??<1==+22A3A3CF@EEGEFEFIAEE???F=FFEDC<B*B9DEECGDDFCEEFFF=FCEFC9@=@D:EECE9@>3;>A@@==;=2=2;::A@::?:@BB
@4WC
GAAAGTGAGTTGGCTGGGAAGCAGCATGAGATTGAAGAGCTAAACAGAGAGCTGGAAGAAATGAGGGTTACCTATGGGACTGAAGGACTGCAGCAGTTAC
+
?@@DA2=:CCADBGIIGIEGGDA;BEDGEEGFEGIIG?DGGHFHABDHGIIFGHGIIGIIGGI@HGBEHDFHEEDEB>AAB;>ACCBBCBCA?AB?CCC:
@4WD
AGCTTTCCCCCTCCTCTGATGATTAAACAGGAACCCAGAGATTTTGCATATGACTCAGAAGTGCCTAGCTGCCACTCCATTTATATGAGGCAAGAAGGCTT
+
@@<DDDFDDFFDDHGEGIGFGFFHDBDHIF<?F?;@DGIB@DEEFGIIDGDBBGG>FBCEHFFHGGH@EIFHFHHFFFFFFECC>;>;@??BBBAD?ABAC
@4WE
CAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCC
+
CCCFFFFFHHHHHJJJJIJJJJJJIJJJJJJJJIJJJJJJJJJJIJJJIJHIIJJJJJHHHHEFFFFFFEEDEEEDDDDDDDDDDDDDDDDDDCDDDDDDD
@4WF
CCAGGACCTCAGCGAGAAAGGAAGTCATCTTCATCCTCAGAAGACAGGAATCGAATGAAAACACTTGGTAGACGGGACTCGAGTGATGATTGGGAGATTCC
+
@@@DBDFDDHDDBGBG@AF@CD?BGGGBGIIIIGIICEHIIIBHIEGHBEIGB8@FFHGIIGICEEEE?A@D@?B@CBBA<AB5<CDA@B;>A@?B.?CCD
@4WG
CTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTT
+
@@@@DFDDFFHGHIGGDEGGGGG@ECAHGEBGIFGCGHHJJIIE?FGHHGDHI:BEBGGG>CEH=CEFFFCEFDB@BDDBDABBBBDD@>@@>AAAB(0)<
@4WH
CTAGCTGCCACTCCATTTATATGAGGCAAGAAGGCTTCCTGGCTCATCCCAGCAGAACAGAAGGCTGTATGTTTGAAAAGGGCCCCAGGCAGTTTTATGAT
+
CCCFFFFFGGHHHIIJJJIJIIIFHGJIJJIJJIJIGEGGGIGGIJGIJJHHHJIIGIJJJJIAGGIIIHHEHHEDFFD@A?CCBDDDDDDD<ADDCDDDE
@4WI
CAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATAT
+
???DDDDDA<AFDFHIG:?EIEHIID@FHGEGEGEAFDFFFGGGCHICFFGIIDHGGGCHIIIDHFEHEEEDEECCCCCACBBC;<CCC>5@CADCEDC
@4WJ
TAATCAACACCGCTTTGCCGATAGAATATGGTCCACTTGTGGAAGAGGAAGAGAAAGTGCCTGTGAGGCCCAAGGACCCTGAGGGGGTTCCTCCTCTCCTG
+
@CCFFFFFHGHHHJJJJJJJGGEIFHHIIGGDEGDGIJIBFFFEFEHGHIGGIGIIIGHHHGHEEDFFFDDDDDDDDDDDDCCDDDDDDDDDDDCCCCDDD
@4WK
CTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCC
+
CCCFDFFFHHHHHIGGHHIGIJIIJIGGIJIHHGHI?FHGIGGG@@GHIJJHFFGHEDEFEECCEACCAC??BCCDCD@ACCCCDD@BDBDDDBBBDDCDD
@4WL
GGACTTGGCACTTTTGAGCGTGGAGTAGGATGCCTGGATTTTTCAAAAGCAGATTCAGGTGTTCATTTATGTGTTATTGATGACTCCAATGAGCATATGCT
+
@CCFFFFFHFHHHJJJGHEIEGHEHEGHIIIIIIIJJHGIJIJJJJJIIGGIDGHGHHG@FF;DEGIJFHHAEHHFFFEFDEEEEEEDDDDDDDDDDDEDE
@4WM
CGGAGTAACTGTCCAAAAGCCATGAAGAGATTAATGGCAGAGTGCCTCAAAAAGAAAAGAGATGAGAGACCACTCTTTCCCCAAATTCTCGCCTCTATTG
+
@CCDFDDEHHHHHJJJJJIIJJIJIJJJJIJJJJIIJIJJJJDHGIJJJJJJJJJJJJJJJIGIIGHGIHHHHFFFFFFEEEEDDDDDDDDDDDDDDDEC
@4WN
CTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTAT
+
CCCFFFFFHHHHHJJJJJJJJJJJIIIJJJJJJHIJJJJJJHIFIGGIIGHH?EHHHFFFFFFEEEEDDDDDDDDDCCDDDDDDDDDDDDBBDDDDDDCDD
@4WO
CACAAGTGGGAATGAGGCCCTCCAACCCCCCCACACCATCCAGCACGCCAGTGTCCCCACTGCATCATGCATCTCCAAACTCAACTCATACACCGAAACCT
+
@@@ABDDDBDCFDFHEEFHDFEGGIIIIGGGGIIEEHJAGD>@?E>44?>9>CEDDAACDDDC@CCCCCC>@A@>CCCC?>ACDDA>>@CDCCCB9B<B??
@4WP
CTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCT
+
@@@DFDDDDHHHGIIJIIJIJJJIHIGHIHGGIDFEIIJGIJFHHIGIIJIJJIIIJGHIIGGHHEFFFCCDDCBDDDCCDDDDDDDDBDD?BDDDDCDDC
@4WQ
GTGCAAACAGGAGGGAGACTGGAGCCACCAAGAAATTGTCCTGATGATCTGGGGAATTTAATGACCCAGTGCTGGGCTCAAGAACCCGACCAAAGACCTAC
+
==?:BDDDFDHAFGA1@CDHGAHCEHIGHIIHEEHIGFHBGDHIIIBHDHH4BGCBGEHIIGEECEHDB;>;@@@BC=ACC>>CCBB@BBBBB@C?<CCCA
@4WR
GACCCTTCAAATTCTCATTTTATTGCCTGGACTGGTCGAGGCATGGAATTTAAACTGATTGAGCCTGAAGAGGTGGCCCGACGTTGGGGCATTCAGAAAA
+
>==AAAAAB@B>=+4A?2?CBCB?+@>4@33+2?:111::04899=ABABB>><A=ABBBBBAB93>A>=>>=);=>>====76=999;;&+83::??==
@4WS
AAATGGGGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACC
+
???DBB+2<8AD>CE188+CEE?<EC?E>@DBDDD9;?DBDBBD(7ADC@;/@A===A;A37;A;A;;?;;8?9=5<+8<>3>>A8A>AAAA(:<9<8912
@4WT
GTCGTCCCCTGGCTCAAGGCAGATCCAGCTGTGGCACTTTATCCTGGAGCTGCTGCGGAAGGAGGAGTACCAGGGCGTCATTGCCTGGCAGGGGGACTACG
+
=1:DDABDFFD8BA>?GF?BAG?CFGHIA<911C;):?FHB?DB99/9??2CH@FAFB84:B;?D?=(6;AAAB:5?'50?43@C3><83<BBB9&583><
@4WU
CCAGATAATCAGCGTCCACTGCTGAAGACAGACATGGAACGTCACATCAACGAGGAGGACACAGTGCCTCTTTCTCACTTTGATGAGAGCATGGCCTACAT
+
@@CDDEDFHFBCFHFFBBDBEH9GEEHGHIIHIIIIIEE@GGGIGGGHHHIG?AEBHH@CEF=?CDDC;;@CCACC>CCCDDDCCCCAABC::<?CAC<AC
@4WV
TGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTC
+
@@CFFFFFHHHHGJJJJJJIIIJJJJJJIGIIJIIIJJIJJIJIJJGIJGJJIJIJJIJGJJJFHFFDDEDDDDD?CDDDDDDDDDCDDDDCCDDDDCDDD
@4WW
TGGAGATGTTCTTACTGGAGACTCAGGTGGAGTCATGCTTATATGGAGCAAAACTACTGTAGAGCCCACACCTGGGAAAGGACCTAAAGGTGTATATCAA
+
CCCFFFFFHHGHHJJJJJJJIIJJIJJHGIJJHIJJJJJJJJIJIJHJJJJJJIJJJJJJJEGFHJJJIJJHGHHHFFFFEEEDDDDDDD>A>CDFDDED
@4WX
CTCCTCCTAAAAAGACGAAGAAAAATAATAGCAGCAACAGCAATGTGAGCAAGAAGGAGCCAGCGCCCATGAAGAGCAAGCCCCCTCCCACGTATGAGTCG
+
@?@BDBDAFD?CAF7EDA)A8FAEH;FEECBBCDHGGIGGCGACFD>FB;BCFGICCDHIGAC==<ACC??CCC:=?CC?BBBB>BB@8389((+9>C(49
@4WY
CAAGTGCAAGCCTATGTCCTATGAGGAGAAGCGGCAGCTCAGCTTGGACATCAACAAGCTCCCCGGCGAGAAGCTGGGCCGCGTGGTGCACATCATCCAGT
+
;=?D=B;?F<BF:CGFFI<?:C?AB3E1FB@?:@@FF?@BFF3*8868==@77CA@E3(7.7?9/398=BB>B?A>38<2509&0<++(:4+(((4(4>+(
@4WZ
CTCCAGGTCACCTATCACGACAAATCACCGGCCTTCTCCTGACCCCGAGCAGCGGCCCCTCCGGTCCCCCCTGGACAACATGATCCGCCGCCTCTCCCCGG
+
C@CFFFFDHDDHFIJHGIIJFGGIJGHIJJIJJJJIGII@FFEDHGJJIIGECBBADDDB@B?=8;BDDDDD@ABACBBBDCCCDDBDD9>B<@CCDCDDB
@4X0
GGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTTCAAGTCAATATAGCCAACAGAGCAGC
+
CCBFFFFFGHHHHJJJJJJJJJJJJJJJJIJJJGIJJJJJJJJJIJJJJJJJJJJJJJJIIJHFFHHFFFFEEEEDDCDEDEEDEDDDDDDDDCDDDDD
@4X1
CCCCTCAACCCCTGTTTTCCCCTGCCTTCCTTGCAGAGGCCATGGAGGACGAGGAGAGACAGAAGAAGCTGGAGGCCGGCAAAGCCAAGCTTGCCCAGTTT
+
CCCFFFFFHHHHHJIJJJJJJJJJJJJJJJJIJJJIJJJIJJJJJJJIIJIIIJGHHHFFFFFEEEDEDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDE
@4X2
ACTGACCACTTTGGCAGATGAAGCTCAGTCTCTGAAAGATGAGATCGACGTGCTGAGACATTCTTCTGATAAAGTATCTAAACTAGAAGGTCAAGTAGAAT
+
1:+<+?AAB>B77=@BAAAA@?7@3A3++711?=1=?<*?=A>:0?3)4:A<=A<A2>A94.=AB===>AAA>=..7?>?@@@@@@>??=53;=9=5=:??
@4X3
GAAGACCCTTCTTATGACTCAGTCAGAAGAGGAGCTTGGGGCAATAACATGAATTCTGGCCTCAACAAAAGTCCTCCCCTTGGAGGGGCACAAACGATC
+
@C@FFFFFHHGHHIJJIJEHJJJJIJJIGIJJGIJJJJJJJJJJIIIIJIJJJJJJIGIJJIJJJJJHHHHDDFFFFDDCEDDDDDDDBDDDDDDDD?B
@4X4
GGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTT
+
CCCFFFFFHHHHHJJJJJJJJJJHJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJIIJJHHHHHHFFFFFDDDDDDDDDDDDDDDDDDDEDDD>>9BD
@4X5
ATTTGGTGTTGATGATTCTTATTCTGAACAAGGAGCACAAGACAGTCCGACTCATCTAGAGATGATGGAAAGTGAGTTGGCTGGGAAGCAGCATGAGATTG
+
@@@FFFBDHHHHHJHIIJJJGIIGGIJJIJJJIGIIJJJJIIJJJJJJJJJBHIJIJGHAGADHIJGIGHHHCEFFFCEDEEDDDBCDDDDDDDDDDDDDC
@4X6
CAATCACCTGAGCTCACCATAGGCTAATAGAAAACAACCGAAACCAAATAATTCAAGCACTGCTTATTACAATTTTACTGGGTGTCTATTTTACCCTCCT
+
<<;==94;@>)24))9;(26@>)2)2=4;8<:<:>71=?;3=(<<737>?888>;?3)36)=1>??86::=3.=;;>8(.=7;'3-:=======:8<5;/
@4X7
CAGGGACCCAGGCCGCACCAGGAGAACAACCACCAGGAGTCCTACCCTCTGTCAGTGTCTCCCATGGAGAATAATCACTGCCCAGCGTCCTCCGAGTCCC
+
;::AD:AD?<::<<C<??GEGE?:FDBB?86;;;DFBAF8=)8@8C;@67?E37?DDB;?;@>66;;5=AB@B>B55AB5:?B>980225<>95.9+<AB
@4X8
CTCCTGTGACTCTCACCTCTCAGACAACTAAGACAGATGACCCCCAATTGAAAAGAGAAATAAGGTTAATGAAAAACAGAGAAGCTGCTCGAGAGTGTCGC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJIJIJJJJJIJJIJIJIIIHIIJIJJJJJGIIHHHGHHHFFFEEEDEDDDDDCCBDBDD@@>CB@
@4X9
GAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCAC
+
B@@FFAEFHDFHGIJJGJJJIIJJIJJGIJIIIJJJFHGIIGIJGIEGHGGIIHGHEDFEDEEEDCDEDDCDDDDBBDDDDDB?BACDADCDCDCDDED
@4XA
GGACAGATAGCTGGCGTGGATAAAGATGGAAGGCCTCTACAACCCCACGTCAGAGTGTGGGATTCTGTTACTCTATCCACACTGCAGATTATTGGACTTGG
+
@@@DDD3+C<CCBF7F@@E1A9ACCG@?GIIIC3B?BBFF>F<?FFF6FCFEFDE77?=AD=;BDDBDCA@>;>AABBB3@?<@:A9:@B@>BBA>:>AAB
@4XB
CGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCG
+
@CCDFFDDHHHHHJJIIAFG@FGCHHGHIFGFGIGJJJIGHIIIIHHBDFFFEDFEEECCCCCCDDDDDDCDDDCDBDDDDDDDDBBCDD>CCCDDDDDDD
@4XC
CATTGAACTGTTGCACCGCTCCAGGTCACCTATCACGACAAATCACCGGCCTTCTCCTGACCCCGAGCAGCGGCCCCTCCGGTCCCCCCTGGACAACATG
+
@@@DADDDBHHHHIIIIFIGHEIACGC>BD<DGGIEGG:DHGICGIHIIIBEHFEEE>>BEDEDCD>@BCDDBBBDD<B@BB59<<A@B<?BAD>?8?9:
@4XD
TAAATAGGAAAGGGTACATGCTGTTATTTAGAAAATGATTATTATTGTAAAAGATGCGGTGGGGTAATCTGATTTATGTTGTAAGAACTTGGTACGTGTAT
+
-5(=(@:)2).28(():..=>?8=).)9))26).61.:)))))).))))0))00)))0(-'-'53')).<:).)).))..(.(((-(((-((,((',3(((
@4XE
TGTGGTGATGACATCTCCTGTGACTCTCACCTCTCAGACAACTAAGACAGATGACCCCCAATTGAAAAGAGAAATAAGGTTAATGAAAAACAGAGAAGCTG
+
BC?DFDDFHHHHHJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJIJJJJIJJIJJJJJJJJJIJJJJEHHHHFFFFFCEEEEEEDDDDBBDCDDDDDDD
@4XF
CAGGACCTCAGCGAGAAAGGAAGTCATCTTCATCCTCAGAAGACAGGAATCGAATGAAAACACTTGGTAGACGGGACTCGAGTGATGATTGGGAGATTCCT
+
@@@ABD??ADHHHHI@FBFEGHHIGE@EGDGABDHDBGHFHGGHGF=FBFCFHGHHGEIGIEIIGEE?A??CBDC<35?@<@59@CA35>C?ABBB?A@CC
@4XG
GTCGGATTCCAGTTAAATGGATGGCAATTGAATCCCTTTTTGATCATATCTACACCACGCAAAGTGATGTATGGTCTTTTGGTGTCCTGCTGTGGG
+
@?@DDDFFHGGFHIHGEH@DF>CFHICHCHIGGEGIIIGIEDDGIIGIIBHECEII=BF@FHEG.7AC;==CEB.7@DD>ABC@?C@;A@CCDDDB
@4XH
CGCCCCTCTAAGCCCGGAGCCCGGCGCTTTCCCCGCAAGATGGACGGTTTCGCCGGCAGTCTCGATGATAGTATTTCTGCTGCAAGTACTTCTGATGTTC
+
?<@DDDDDDBF4:AFGGGIGIIAGEG<@5;F@=D<EBDAC>CCCCBB853:<<B68BB7CA>394>CC>CC:>>4@@@CCCC@>>((44:>ACC4:>@A3
@4XI
GCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAATGTGACTC
+
@@@DFFFFGHHHHIIGEHIJJIIIIJIJGJJJIJIIIIJJIJIGIJIIGIGGIJIJIJJJIIIJJJHGFGFFFEFEBBEDDDBDBD=BDDDDCCCCDEDDD
@4XJ
CAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGG
+
C@CFFFFFHGHHHJJJJJJJJIJJJIJJIJIJJJIJIIIJJIJJJJJJJJJEIIGJIJIJJJJIEIJJHFGHHHFFFDDEDDDDDDDDCEDDDDDDDDDDD
@4XK
CTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTAT
+
CCCFFFFFHHHHHJJIIIJJJJJJIJJJJJJJJJJJJJJJJFHIIIIJJJJHEHHHHFFFFFFEEDEDDDDDDDDDDDDDDDDDDDBDDDDDDDDDDDDDD
@4XL
GGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCT
+
@@@DDBBDADFFHIIIIIIGGHG=?AEEHGIGGGIGGIIEIIIIGIBFDFHIIIIIGGIHIIIGII=DE?EHHHHCEEEECCCACCCB@AACCCCCCCBC
@4XM
AGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGC
+
@CCFFFFFHHHHHJIJHGHIIJJJEGJIJIIIJJIJJJIJJGIJIJJJIIIGHGIJJJJJJJJJHHHHHFDBDFCECEEDDDCBBDDDDDCCCDDEEDEDD
@4XN
GAAAAAGAAAAAGGAAGCAGAGGAAGAGGATGAGGAACTCTCCAACTTTGCTTACCTCTTGGCCTCTAAACTTAGCCTCTCACCAAGGGAGCATCCCCTC
+
@BBFFFFFHHHHHJJJJJJJJIJIJJJJJHIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHHHFFFFFFEEDEEEDDDDDDDDDDDDDDDDDD
@4XO
CTTTTTTTTTTTTTTTTTCTTCTTGTCTGAGTATTTCAATTTTTTTTTGAAGTTCTTTGATTTTAAGAGCCATTTTTTTTGCCTTTAATTTTAC
+
===AAAAAAAAAAAAAA6).)).>;(((-5---;;;(5(59;59;:75&8:(3((++33(3:3(+58((+83:=;883&50(+4::3((+33((
@4XP
CTGAAAATCAAGAAAGAACCCCACAGTCCATGTTCAGAAATCGGCTCTGCCTGCAGTCAAGAACAGCCCTTTAAATTCAGCTATGGAGAAAAGGGCCTGT
+
;;?DDBDBDH?FFH@GHGEF@?AGECGC@?GDHGIGHBEGA@GI:?DB8DFGGGGGIAGGE@@@EHFE=@DC@D@C@@CA;;>@CC>BCBCCC(88?BB:
@4XQ
CTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTC
+
CCCFFFFFHHHHHJJHIIJJJHJIHGHJJJJJIFIJJJIJJJJJIIJJHIJIJJJIJIIJIJJJJJJHHHFFFEDEEEDDDDDDCCDDDDDDDDDDDDDCC
@4XR
GACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTG
+
@@CFDFFFHHHHHJJJIJJJJJIIJIIGGIHIIJIJJJIJIJIJIIGHJJJIIIJGHIGHHHHHFFFFFFECCEEDDDDDDDDBDDBBDDDDCDDDDDDDD
@4XS
ACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGAC
+
@@@D;BBBHHH?B>HHGIGIIIFGGHBDGIGGIGHIGGHHEGGHIICFF@HIIIFIGGHHEFEDEDCD@CB8@BCCCCB?B<?BBBBB?>ACC3@CCCCC
@4XT
CTCACTTTGATGAGAGCATGGCCTACATGCCGGAAGGGGGCTGCTGCAACCCCCACCCCCTACAACGAAGGCTACGTGTATTAACACAAGTGACAGTCA
+
@CCFFFFFHHHHGIJJJJJIIGIJJJIJJJJJJJJJJJJJJIJIJJGIHGHHFFCACDDDBDDDDDDBDDDDCCCB2?3<BDDDDCDDDB:@ACCC@CC
@4XU
AACAAGCTCCCCGGCGAGAAGCTGGGCCGCGTGGTGCACATCATCCAGTCACGGGAGCCCTCCCTGAAGAATTCCAACCCCGACGAGATTGAAATCGACTT
+
CCCFFFFFHHHHHIJIJIJIJJJJJIJJIJJHHFBDEEEEEEDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDEDDDDDDDDDDDDDDDDDDDDDDDDD
@4XV
CACAAATTCGAGCATCACCTTCTCCCCAGCCCTCTTCACAACCTCTCCAAATACACAGACAAACTCCAGAAAGCAAGAATGCTACTCCCACCAAAAGCAT
+
@<?DDA?BF1C?@EGIIII@FE>EBG?GDEEH??CD<G><FAHIIGF>FBCHC8=BF;FFGGH;@EHE;ACB;;?AA>A@@ACCCCCCB?B8<9?<98AC
@4XW
CGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTT
+
@<@DFFFDDHGFHGIIIGIBCEBD?GGBGGGGHEHEFGGIGGEGIEGHAGI>BFGIIIIFHEHFECFCCCABEB@AB>CCCACB:39CC?@CCCCCCCCAC
@4XX
GGACTTGGCACTTTTGAGCGTGGAGTAGGATGCCTGGATTTTTCAAAAGCAGATTCAGGTGTTCATTTATGTGTTATTGATGACTCCAATGAGCATATGCT
+
CCCFFFFFHHHHHJJJJJJJHHJIJGIIJJJJIJJJJIJJJJJJJJJJJJJJIJJJJJJCGHIJJJJIHHHEHHHFFFFFFEEEEEEEDDDDDDDDDDEDE
@4XY
TACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTT
+
@@@FDFDFFDHHHIF@AEDHHIIIIHGIIIIIIIIIIIIIIIGDDGGIEHIIIIIIIGIGIIIIECHHEEEFC@B@CCEEEDDDDDDDCDDDDDDDDDDD
@4XZ
GCGATGGGAACCCCCTCATCATGGTCTTTGAATACATGAAGCATGGAGACCTGAATAAGTTCCTCCGGGCCCATGGGCCAGATGCAATGAACCTTGTGGAT
+
7:;+???A+==+@?AAA97AB:4@A<<@?4=AA9A*:::**77**)=;>1(3=AB).=A))=)7=)--49=@==>?===59(9;9;3;(+(+8(+8(88((
@4Y0
TTCTATAGAAGACCCTAACAGTCCAGCAGGAAGAAGGCATTTGCAGCTCCAGACTCAATTAGAACAGCTCCAAGAAGAAACATTCAGACTAGAAGCAGCC
+
@@@FDEFFHDHHHIJJJEIGGH>EGHHCHHGEEEGGIGIGIEIFIIDGHGHHBHGGGIIHGGIIGIJIGIIFEEHFFFFFCCCEA@CAC@>CCDCCDDDD
@4Y1
CCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGAT
+
CCCFFFFFHHHHHJJJIJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJIIJIIIJJHHHFFFFFEEEEEDDDDDDDDDDDDDDDDDDD
@4Y2
GAACACAACACCATGGTTGGCAGTGCGGCCAGCCAAAGCTTTCCCCCTCCTCTGATGATTAAACAGGAACCCAGAGATTTTGCATATGACTCAGAAGTGCC
+
CC@FFFFFHFGADHGIFEHHGIHBFHIIIIIIIIIIIEHIIGGEIIIIIIHHHHAABCEFFFFEEEDDDDDDDDDDDDDDDC>CDCDECDDDDDDDDCCCD
@4Y3
GGGAAAGCGAGAGGGAGACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGG
+
CCCFFFFFHHHHHJJJJJJJIGJIHIJJJHIJJIJIIIGIIHFHHFFFDDEDEDDDBDDDDDDDDDDDDDDDDEDDDDDDEDDDDDDDDDDDDDDDDDDDD
@4Y4
CTCAAAGTGCGGTAGGGCCTTTTGTTGTCCTGCTGTGGGATATCATGACCCTAGGGGGAAACCCCTATCCTGGGCTTTCTCCTGAGCGGCTGTTCAACCTT
+
<;;?@?)<6)(((2(2-)(-24:>18>))...))00.)(6))>>))9)<>7?1;375''5==7==(56(:370;(8;(,705:;<(+&085&+(++3:/2+
@4Y5
TGCTAATTTACAACAAGCAAGAAGAGAAAAGGATGAGACAATGAGAGAATTTTTAGAGTTGACAGAACAGAGTCAAAAATTACAGATTCAATTTCAGCAAT
+
C@@FFFFFHGHGHJJJIJJJJGGJCGHIJJJJJJJJIIJJIJJJJIJIJJJJJJJJJJDGHIIJJJJJJJJHAEHHHFFFFFEDEEEEDDEEEDDEDDDDD
@4Y6
CAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACC
+
CCCFFFFFHHHFFG>GBFECHIIIGGGHIIIIIGIIIIGHIIIDGHIIGIIIGEHGDHFHFHHFFFFECACCDDDDD@BDDC@>AACDA<ACDDDDDEE>@
@4Y7
GAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTC
+
@?@FFFFFDHHHGJJJIJJIIFGJGGGHHIFHGGIIJJEHGIIIJJIJIHEIFHEGIIJHIEHGGIHEHFHHHFFFDDDDDCDCC@CCDDDDDD?BDDD@C
@4Y8
CCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATAT
+
:?;D?D?AFFDDBGHDHBEGHEE<FC;EEFE9?:CGD@6BAEBDFEGGI=@>AE;=@E?<DDC9;==@;89CCCCCB:@CCCCCC<CBBC?B5?A@AA>A>
@4Y9
AAGCTTTCCCCCTCCTCTGATGATTAAACAGGAACCCAGAGATTTTGCATATGACTCAGAAGTGCCTAGCTGCCACTCCATTTATATGAGGCAAGAAGGCT
+
CCCFFFFFHHGHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJIJJIIJJJJJHGIJJJJJJHHHHHFFFFFFEEEEEEEDDDDDDDDDDDD
@4YA
GGCTTCCTGGCTCATCCCAGCAGAACAGAAGGCTGTATGTTTGAAAAGGGCCCCAGGCAGTTTTATGATGACACCTGTGTTGTCCCAGAAAAATTCGATGG
+
B?@DDFFEHDHFHGGIJJIIIHIHGGHGHGIJGGGFHHHHHIJCGIGGHIIJJIGHGGIJHIJHHHHGEEEFEFF>C>ACEDDCDCDCBCDDDACC@AACD
@4YB
CTAAAGGATAAATTAACAACTGCTGATAAATTACTAGGAGAATTACAAGAACAGATTGTGCAAAAGAACCAAGAAATAAAAAACATGAAATTAGAGCTGAC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJIJJJJIJJIJJJJJJJJJJJJJJJJIJJJIJIHJIJJJJJIJJJJJJJHHHHHFFFDDDDDDDDDDDCDDDDDDD
@4YC
CCTGAGTACAAGCTGAGCAAGCTCCGCACCTCGACCATCATGACCGACTACAACCCCAACTACTGCTTTGCTGGCAAGACCTCCTCCATCAGTGACCTGA
+
@@CFDFDFHHHDDGIIIFH;DGECHIIIJJIJJJJJJFIJGIIIFIFEGHHHHFFFFDDDCDCCACCCCDDCDCBDD<CCCCDDCDDCACC@:>CCD@CD
@4YD
CTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATG
+
???DD4:=DABDDEEEEB:)@ED>?CDDDCIEE*??DD?8??D@6;A8@C7C;?@DDDDAAAA;AAD>>=;?<39??8<>??A4:AA?<>??<??A<>AAA
@4YE
CAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGGCAATATAGCCAACAGAGCAGCAGCTACGG
+
???DDDD;?A:22CEEBE@C+A;F;F8?C??D*:CDEDDDD6DDD?2BCE)/88@;;=CA6=AD13.??7.(6@>;A5>A>AA=8?<>>:>988>1(:>?;
@4YF
AAAAAGACGAAGAAAAATAATAGCAGCAACAGCAATGTGAGCAAGAAGGAGCCAGCGCCCATGAAGAGCAAGCCCCCTCCCACGTATGAGTCGGAGGA
+
?@@DDDBDF<FDAFF@:8CE<F9?B*8CCD>FF>F9*:9BDDD>;FF;2B=((8@;;@EBB9BDCA@@CB?B@B<?@BB@B9<9BBA3@>4:<@..9?
@4YG
AAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCAC
+
CCCFDDEFACFFHGGGHGHIIJJJGIGGFFHIIGGGBHGGDGA>GHGFGGIIGDEDFBCBACECEEEDC@DDDDDB?B?B??C?CDDDDDDCECACCDD<A
@4YH
GTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAAC
+
@@BFFFFFHGDFFIGIJJHEGIJJJGGJJJJJGIJIJJIJIIJGGIFCFHGJIJEIIJIJJJJHHHHHFFFFFFDECCDCDDDCC@CDDBCDDDDDDDD
@4YI
AAGGAACCTCCTCCTAAAAAGACGAAGAAAAATAATAGCAGCAACAGCAATGTGAGCAAGAAGGAGCCAGCGCCCATGAAGAGCAAGCCCCCTCCCACGT
+
C@CFFFFDHHHHHIJGIJIGGIGIBHIIJIEIIGGHGHIJJJIIEHIIJJJIIIIIFHIIIJHHFHFFFDDCDBDDDDDC>CB?CDDDDDDDDBDDDDDB
@4YJ
AGTTTGGAGAGGAACACCAGTGAAAAGGGGATATGACGAGAGCGGAGGTGATCGGGGGATAGAAGGGGGGGGGGGGGGGGGGGGGGGGGGGATGAAAGAGC
+
((0-5)(.)2(((((()2(()2)))))(1/(().0))(((((('-'''(..).(59/')&((((+2)00&&&)0&)&&00&0&&&)&))&&&&((((((((
@4YK
CAGTAAGGTACGGAGTAACTGTCCAAAAGCCATGAAGAGATTAATGGCAGAGTGCCTCAAAAAGAAAAGAGATGAGAGACCACTCTTTCCCCAAATTCTCG
+
CCCFFFFFCFHHHIIFHIJJIHHIIJJIGIJIIGHIJJJJJIHIJIJJIJIJDHIJJJJJJJJJIJJHEHHFFFFFFACEDCDDDDDDDDDDDDDCDDDDD
@4YL
GCAGAAGAAAGCAAAAGGAGCAGAAATAAAGACAACAAATGAAGTTGTTTTGGCTGTGGAGTTTCACCCAACAGATGCAAATACCATAATTACATGCGGT
+
=8=B1===CAF;<F;:C?<<<3A;<AFG>??:C:9???FDBHBGHDDH@FDB;88B(8C8=)===@@=CAHB?6;(;3@>6;5;ACC;::>;5@D;5300
@4YM
CTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTC
+
B@CFFFFFHHGHHJJJJJJGHJJIJJJJIJJJJJIJJIJJIIIJIJJJJGJJECHHHHFFFFFFFEEEDDDD>CDDDDDD@DDDDDDDDDDDDDDDDDDDD
@4YN
CCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGG
+
@@<DDDDDFFDFHJGGHGHFEIGDHIHIIAFGIIIIIIGIJJGIBFHIJGIGHHHGIGGGGHCCEHHHFBCFDDEDECDDCDD@CCCDCBBA9>C@DD@CD
@4YO
ATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCA
+
@@@FFFFFGGHHGGGIJJIJJJDHIJIJIIJJJJJJGGIJJJFIJJIJJIIIJJJIIIGJJJJJIJHHHFFFDCEEEDDDDDDDDDDDDDBDDDDDDACC
@4YP
CCAAGCCATTATGATGATGGAGGAATCTGTTCAACATGTTGTCATGACAGCCATTCAAGAGCTGATGAGTAAAGAATCTCCTGTCTCTGCTGGAAATGATG
+
?@?BBDDDHDFFAGH@DFFBHB;G@GBBCHGIGDDHBD4CBGI<?B9D<@???9B?DBDA2)88B;@@AHA@==@=@EHHHHH?C>77;;>C@;;@CC5;>
@4YQ
TGACTTGATTAGAGACCAAGGATTTCGTGGTGATGGAGGATCAACCACAGGTTTGTCTGCTACCCCCCCTGCCTCATTACCTGGCTCACTAACTAACGTG
+
@@CDDEA?DFDHDGHFHIGIIFCGHHIHGG)?1CDBGGAD?BDHIDC@?D?8=BD@FGCFEHGIICEADDDABDDDCEC@@::ABCA@CCC9@CCDD?92
@4YR
GTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGC
+
@?@DDDFFGFFHFGIEGGGHGEFHIFHEGGGGCHIEF?FGFHGHEHGIJJIGCGIG@@AHGHHFBHFCEBDEC>C@;>CD>@CCCDACDBBBCCDCCBBBB
@4YS
TTTTGTGGATGGCACCAGAAGTCATCAGAATGCAAGATAAAAATCCATACAGCTTTCAGTCAGATGTATATGCATTTGGAATTGTTCTGTATGAATTGATG
+
@@@FFDDFDFFHFHJEFGDHGHEIIG9GIEIGCFHG?FHHGHGGGBFHDGGHIJIIGGGIGGHCHFFGGCHAEDEEGEAAHFHFBDDDE@>ADEDEECDEC
@4YT
CCTCAGCAGTTACAAGCCTTCAAAAATGAAGTAGGAGTACTCAGGAAAACACGACATGTGAATATCCTACTCTTCATGGGCTATTCCACAAAGCCACAACT
+
<@BFFFFFGFHHFIJIJJJJJJJJJJJJJJEGHIIIICGHIIIIIJJIJJJJJIHIIJHIJJIJIJJIJHHHGHHFFFFFEEEEEEEEDDDDCCDDDDDDD
@4YU
CAACTATTCTTCAGTATGCACAGACCTCTGATGGACAGCAGATACTTGTGCCCAGCAATCAGGTGGTCGTACAAACTGCATCAGGAGATATGCAAACATAT
+
CCCFFFFFHHHHHJHGIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJBFHHHIHIHHHHFFFFFFEEEEEDDDDEDDEDDDDDDE
@4YV
TTTGTGGATGGCACCAGAAGTCATCAGAATGCAAGATAAAAATCCATACAGCTTTCAGTCAGATGTATATGCATTTGGAATTGTTCTGTATGAATTGATG
+
@CCFDEFDHGHHDGGHHJJJEHIIJJJJJJJFIIIHIJIJJJIIJJJJJIJIJIIIJJGJEFGIIIGHEIIIEIIJJJHHHHHHFFFFDEFEEDDDEEDD
@4YW
ACTCATCAACAGCAGCTTGAAGAACAAGACCACTTATTAGAAGATTATCAGAAAAAGAAAGAAGACTTCACAATGCAAATTAGTTTCTTGCAAGAGAAAAT
+
@CCDFFFFGHHGHIGJJJEEIJJJIJHGBGIGGHHIJJGF?GGIIIHJIIJJJIIIEAGGCGHECCHGGEHCHHHHHFFFFFFEEEDEECCCCCCBDDDDD
@4YX
CCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGT
+
@@@DFFFFHFBHHIGHJIGICGEHIIIJGHIIGIHIJJGHHEICHIJJIAEEH7?EEEDECBADCEEEEDDDD5@CDCDBB<@8<CC?DDD?CCDDCBBD@
@4YY
CTCCATCGCAGTCCATACCAGATAGCAGCTACCCCATGGACCACAGATTTCGCCGCCAGCTTTCTGAACCCTGTAACTCCTTTCCTCCTTTGCCGACGATG
+
CCCFFFFFHHHFHIJJJJJJJHIJJJJJJJJJJJJJJJJJIJJJIJJJIJJJIJJJHHFFFFFDEEEEEDDDDDDEDEDDDDDDDDDDDDDDDDDDDDDDD
@4YZ
GAAAAGGGCCCCAGGCAGTTTTATGATGACACCTGTGTTGTCCCAGAAAAATTCGATGGAGACATCAAACAAGAGCCAGGAATGTATCGGGAAGGACCCAC
+
@CCFFFDFHHGFBGGIGGHIIIIJIJIGIGFHJIIGFBG@BHGIIGIIIJJJIIJHIGHHHIGHHHGHHFFDDCACEEBDDDCCCFDCBDDDDDBDDDDB?
@4Z0
CACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTG
+
@C@DBEDFFHGHFJJIIJJJJJJIIIJJIGIJJJJIJJGIIIJIGIIJJJJIJJEHJEIGHIIHHE:EHHEHAEDFFFFC@B@CDBDB?BDDBCBDDBCDD
@4Z1
GCTCAAAGATGCCATGAACTGGATATGCAGGTTGCAGCATTGCAGGAAGAGAAAAGTAGTTTGTTGGCAGAGAATCAGGTATTAATGGAAAGACTCAATC
+
???;??DDB+CDDEABAADEEB3<ACE<9EC?CEADE@)?D:D>@D??DBCDE@?9=BBB<CCACA@ACD=C;A?A@@A);3;;(66@>3>?>>A>AAA:
@4Z2
GTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGAT
+
@@@DFFFFHGFFDFHIJIJIJJIJJJJIJIIIJJGIJJIGIIIIJJJJJIJJJJGIJIJJJJJJHHHHHFFFFFEEEEEDEEDCDDDDDDDDDCCDDEDDD
@4Z3
CTGTTAGTAAAACACACAGGTCAGCAGACAGGGCCAAAGGAAAGGAGAAAAAGAAAAAGGAAGCAGAGGAAGAGGATGAGGAACTCTCCAACTTTGCTTAC
+
;@;DDDDDAFBFFIEFGIIF<FEFFIF9CBBDCFG@DGF@?B??2?FFFFFCFCEFE=AEFACC>@@?=@@B;=?=?>ABAA@BBB@BB>>ABB@AABBBB
@4Z4
CCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGAC
+
CCCFFFFFHHGGHJGJJJJJIIIJJJIIJJJGGIJBHGIIHIIJJJJJJJJJJJIHHGHGJIJJJJJHHHGHFFFFEEEEEDDDDDDDDDDDDDDDDDD
@4Z5
GTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGC
+
@@@DFEFDACFDHHG@FFHICFHIGGEFACGGIIDHIIIIID9<FG@FHIIIIIIIIIIIIEHEFGHFFFFDEDCECCCC<@CACDDEDB?CCC?CCCCDB
@4Z6
GTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCC
+
?@@D?DD;FFCFHHHGG>ACGEIIECHGIIIDGICCFGE=DH>BFEHFHI-;CCCCHEE@B7?CACACACCCCCCC@<<C@CCCCCC5:@CC@8?<?8<
@4Z7
GCAAGAGAAGTGCATGGTGGGCAGGAGCAAGCCCTAGATAGCCCCAGAGGGATGCACAGGGATGGGAACACTCTGCCATCCCCCAGCAGCTGGGACCTGC
+
@<@D=BDDHH2ABF>FEEB=GHGEBGGCGHGGG@D?@EFGHIICGG==FC@A;@GGE3;??DBDDCC@==A@C3>3:>:?BB@B7@A9<?CC<?A@B?C?
@4Z8
AGACAACAAATGAAGTTGTTTTGGCTGTGGAGTTTCACCCCAACAGATGCAAATACCATAATTACATGCGGTAAATCTCATATTTTCTTCTGGACCTGG
+
C@@FFFFFFHHHFIIHGHIEGIIIJJJCGIJIJDIIIIIIIGICHC@FHHJIJJJIJJDFGGIJJJJGFFH9?AECECCEDDDEEEEDDDDCCDDDDDB
@4Z9
GCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGAC
+
@@CFFFFFHHHHHJJJJJJJJJJIJJJIJJJIJJJJJJJIJJIJIIJJJJJHIJJIIJJJJIJJIHHFHHFFFFFEEEEDDDDBDDBD<AADDEEEEEDDB
@4ZA
CCGGCATGCCCAACGACCCCAGCCCCCTGCAAGTGGCTGTGAAGACGCCCCCCGCCGTGTGCTCTGAACAGGACGAACTGGATTTCCTCATGGAAGCCCTG
+
(;;8(:;8>???5=5(5@;(-86((0;=5(.=.0)67(5691;1):85'',,''''&))+++8:2(:;;56:(20088<=2(+3:65(+8:/6;569<3(+
@4ZB
TGACATTATGCCAGTTGCTTTAATGGAAACGAAGAACCGAGAAGGGTTAAACTATATGGTACTTGCTACAGAATGTGGCCAAGGTGAAGAAAAGTCTGAGG
+
@B@FFFFFHHHHHGCFGGHHIIIEHIJJGCGHJIGJEEHAFHGHGEHEIJIGHIJGHGGECHIJIHEEEHFFFFEFFDCBCDDD5>CDCDDDDDCCCCDDD
@4ZC
CCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTG
+
CCCFFFFFHHHHHJJJJJJJJIJJJJJIGIJJIJJJJJJEGIIJJJJJIJJJJIJJJJJJJJIJJJHHHHHFFFFDDDDDDDDDDDDDDDEDDDDDDDDDD
@4ZD
TACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGC
+
?@CFBDDFDHHHDEHGGGGGHIGHIJIJJJEDFIIJJJIJIGIGGIIGGIJJFGIIJJJJIAFEHJCEHEEEFF@DCDC@CCCC@CD?BCBBBBBB<AB
@4ZE
CCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATGACATCTCCTGTGACTCTCACCTCTCAGACAACTAAGACAGATGACCCCCAATTGAAAAGAGAAAT
+
@@@DFFDDFHHFHGIEHGGGIAGGBHFHCEH?FGHGGCDGFHDFGHBGDGHGGIIIIHIGIIGIIIIIIIGEEHHHEHFCFEFFCBBCCCCCCCCCCCCCC
@4ZF
CACCAAGGGAGCATCCCCTCAGTCCTCACCATGCCTCAGGAGGTCAGGGCAGCCAGAGAGCATCCCACCTGCTCCCTGCTGGAGCAAAAGGCCCCAGCAA
+
@@@?DDB7?:D@DHHHBBCEECH@FGGHGHADEGG@B:?D<FD79DG@CHGBEGGCCG;?A>;???BBCCCC@CC@CCBCCC9?ABCC39<82<>@@?CC
@4ZG
CAAACATATCAGATCCGAACTACACCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATGACATCTCCTGTGACTCTCACCTCTCAGACAACTAAGAC
+
CCCFFFFFHHHHHJJIJIIIJJIIJJJIIIJIJIIIJJJJJJJJJJJJJHIIHHI=CHIIJJJIJJJIJIHFFHHEEFFFFFEDEECEDDDDDDDDDD
@4ZH
TTCAGGCAGTACTCAGCAAGGTACAACTATTCTTCAGTATGCACAGACCTCTGATGGACAGCAGATACTTGTGCCCAGCAATCAGGTGGTCGTACAAACTG
+
@CCFFDFFHDHGGIIHJIIIIAEHIGIJIIIJJJIJIDHGIIHIJJJJJIJJGGIJIJIJJJIJICHGIGIGGIIHHHHHFFFFFC>CCBCD;ABBDDBCD
@4ZI
CTTTCTGAACCCTGTAACTCCTTTCCTCCTTTGCCGACGATGCCAAGGGAAGGACGTCCTATGTACCAACGCCAGATGTCTGAGCCAAACATCCCCTTCCC
+
CCCFFFFFHHHHHJJJJJJJJJIJJJJJJJJJJJJJJJJJJIJJJJJIJJJJJJJHHHFFFFFEEEECEDDDDDDDDDDDEDDDDDCDDDDDDDDDDDDDD
@4ZJ
GGGAAAGCGAGAGGGAGACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGG
+
@@@DFFDADFAHAA1CC@E=F:D@DHGAF;9/B9@'5;ACB;A>EDDBCBCC@CCCB@BBBCC<58>0>ACC:>>CCCACA>CCCAB@AC9>@99BB<A<8
@4ZK
GAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTG
+
@@CFFFFFHHHHHJJJJJJJJIJJJJJJJJJJJJJIHIJBFFHIIIJJIIHIGGIIHIEHIHHHHHHFFFDEEEDDDDDDDDDDCDEDDDDBDDDDDDDDD
@4ZL
CCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJGHJJJJJJJJJHHJJJJJJJJJJJIJJIJJJJJJHHHHHHFFFFDDDDDDDDDDDDDDDDDDEDDDDDDDD
@4ZM
CAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCC
+
CCCFFFFFHHHHHJJGEHIEGGHJAGIJJJJJIJGHIHJIIJJIFGIJJJJJJ@GHIIFIJCEEHHDEFFFEECCBDBDDDDDB?BDDDDDDDDDDDDDD
@4ZN
GGAAACCCCTATCCTGGGATTCCTCCTGAGCGGCTCTTCAACCTTCTGAAGACCGGCCACCGGAGGGGGAGGCCAGACAACTCCAGCGAGGGGATGCACCG
+
8??D;22=)+A+<A4+:A?3AA422A3?E>?)0:)89*9*/?D8==3BACEI7.'59?',>;>'''8&559&282((((38((+:49&009&&)&+(((3&
@4ZO
GGGTATGCCACTGGGGCTTAGGATACCACCACTGCTACAGTCACCACCACCCAAGCCTCCTATGCAGCTCAGACTGCATATGGCACTCAGCCTGCTTATCC
+
5(0(-.=).)2).=(2@32))2)9@?<:.((:32:<)7=)09)3:.<;7>?86.(;;6:>?8399>3=)33=))(.66=;5(-,7;(:5(78(7;(822:<
@4ZP
GTTACGCTTCCTCGACGCCACTTCATGTTCCAGTGCCTCGAGCGCTCAGGATGGAGGAAGACTCGATCCGCCTGCCTGCGCACCTGCGCTTGCAGCCAATT
+
@@@DDB61;FFFFBF?FG)?DGDFC4?DFBG@GFFFBFB@D:F;@EEEEF>?.;;B1=>@;AA:5;;??<8?BBB@3(8--<99AAB--95?<>A@??BBB
@4ZQ
AAAAGATTTACAGCAGTCTCTTGTAAATTCAAAGTCAGAAGAAATGACTCTTCAAATCAATGAACTTCAAAAAGAAATTGAAATACTCAGACAAGAAGAA
+
CC@FFFFFHHHHDIEIEHHIJJGCHHIIIJJIJJCGIJGIGIJGHGGGHEIIIIIGHIHHJHIIGIGHGIHGIJIIIJJHGHHEHFFFFFFACEE@CDAC
@4ZR
AGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJIIJJJJJJIIIIJJIJJJJHHHFFFFFEEEEEEDDDDDDDDDDDDDDDDDDDDDDDDDDDDEDDCDDD
@4ZS
TGAGATTTTAGGACAGCAAATTAATGACTTTACCCTTCCTGATGTGAACCTTATTGGGGAGCATTCTGATGCAGCAGAGCTTGGAAGGATGCTTCAGCTC
+
@@<BDDDD<F88C<FFHH<EHGD9EHAHIIB?<FGIIEE>BC9?FGBHF<?B9?FH@G:B@8=FEADHD=C)=A=;?@2?DC@CCC?;?A:<:>>@:@AC
@4ZT
CTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTAT
+
@@@DDDBDB3DC?@GHEHGI>GGGBGHGG=DBDFCFHEGG8;@F@CAEGIGE?;?EE?BEBCDCCCC=BBCCCCCCCCBCCCC>?<@BB@@B<?BCBBCCC
@4ZU
GAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTG
+
@CCDDFDFDDHDHIJGIFIGHJGHIGGHJIEGIIIJGJG?FGCHIGIIHHGGCIGICGEEIHHEHHFFFDDE@CDDDDDC@AACDEDDDDCBDDDDDBDCC
@4ZV
TTTTGTGGATGGCACCAGAAGTCATCAGAATGCAAGATAAAAATCCATACAGCTTTCAGTCAGATGTATATGCATTTGGAATTGTTCTGTATGAATTGATG
+
?@?DD?:;F+AFF@:<CE<CDHCEFHEFBF4C>GIBFFFFFCGF@DFEEC???BB<<BFE:FFE4@7@;4=.77@DE@3?;=C:B>7;B;>AAAAD3((5;
@4ZW
AAACCAAAGAAAAAGGAGAAAGACAAGAAGGAAAAGAAAAAAGAAAAGCACAAAAGGAAAGAGGAAGTGGAAGAGAATAAAAAAAGCAAAGCCAAGGAACC
+
@@@DADDDFHDDB?EGGHGE9AGDBFE9EACGDH;GGEGGIBFHGFAAFCFHI>=AHEHEDDEE>A;;>AC>>BB<AACCCCCBBB??C>CC<?C?BBCBB
@4ZX
CACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGG
+
@@@FFFFFGHHHFJJEGIEHIGGHHIGIIJJIIGGIIIJGHIJGIGGIFIHJJJGEEFHHHDFDDECDEECDDDDDDDDDDDDCCC>CDDCCDCDCCD>BB
@4ZY
CAAGATGAAGGGCTTCTCGTCCTCAGAGTCGGAGAGCTCCAGTGAGTCCAGCTCCTCTGACAGCGAAGACTCCGAAACAGGTCCTGCCTAATCATTGGAC
+
?@?BBDAEHFFHGEHGIGIIIEHIIIIIGE>FGGEDEBFHHI?FGGIIIIEGDCGIDGGGDEC<BBC?CCDDDDBDDDDDBCCDD@@A4@CDCDDEDD@C
@4ZZ
ATGGAACAAGAAACACAAAGAAAGTTAGAACAACTCCGGGCAGAGCTGGATGAGATGTATGGGCAGCAGATAGTGCAAATGAAACAAGAATTAATAAGAC
+
CC@DFFDDBFHHGIIJIJEEGFIGGHHIIJBEHHIHIJIJHGEBGBCHGFHJCG;DED.7=CEEHE?DB@6@ECDDDDDDDDDDCDD?AC@CDDEDDAAC
@500
CGAGCAGCTATGGACAGCAGAGGAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCT
+
?;+AB:D>DDDD3:CEEEDA<C+<FDBEEIIDEEEEIDDDDEIII<9BDDDCDIDCDDCCCCACDDC7@D;A;?=?@????=:>(:>>?AAAA>A>><28(
@501
CCTCCAACTAAGGGTCAGCGAGGACACCTGCCCACTGAATGTTCATTCTTATGACCCCCAAGGAGAAGGCAGGGTGGATCCTGATCTGTCCAAGCCTAAA
+
@<@DDDA?FDH?ACEGG>FGEBAH?9:8??BBBDBG>9?B?FEH@C@=FHBB@=@F@;BE5=ADBBECB?@BBB(5/<>CCC@:AAC:4>>C@:8?CCCA
@502
CGAGAGGGAGACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTAC
+
BC@FDFFFHHFFHIGJJGIIGIGIJJJIDHH?CFB@FGGIIIFFHEHFDEFCCBBCBBDDBDDDDEEDDDDCCECDDDBBCCCDDDB@DDBDDDDBADD
@503
CCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGT
+
CCCFFDFFHHHGHJJJIJJJFHIJJJJJIJIJJJJJJIJJJJIJJJIGIJJJHEHHHHFFFFFFEEEEEDCDDCDDDDDDDBDDDDDDDDBDDCDDDDDDC
@504
GGTGCATCAAGCAAACTGGCATACCCCCATTAGTGCCAGCATCAGTAATCTACTTAGAAGGACTGATGGGGGGAACCGGGAGTTGGACCAAATGAGCCGGT
+
7(73()691));()2.2);())8))2383):3)28<88.():3..9)))0.0<)9)))))(.(<=))).3('))562-&)&)++((+58:6<(((((()0)
@505
CTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTT
+
@@@DDBDD?F?DBEBFHIIIDE<<C<AH<C@?FGC??BHHIGDCDH@HD?BFEGIA8;B@@=7(7?E;;;??;A<;BB=B<?B?=B<<:>CC>>AB?+9)2
@506
CAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCC
+
CCCFFDFFHGHHHJIIIJJJJJJJJGHJJJIIIIIJIIIJIJIIJJIJJJIIIJJJJIJIIJJJJJJJHHHHHFFFFEEEEEEDDDDDEEDDDDDDDD?BD
@507
TGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTT
+
@@@FDDFFGHHHHJJIJJGJJJJJJJJIIJIJJIIJIJGGGIJJIJJJIJJJJJIEGEGGHGHIFIIEEHEHFFFFFFEEEDDDDBBDDDDDDEDDCDCDD
@508
CTTAGGAGTTGGAAGTGGAGAAATCAAAGTAGCAGTGAAGACTTTGAAGAAGGGTTCCACAGACCAGGAGAAGATTGAATTCCTGAAGGAGGCACATCTG
+
@@@DDD?DBFFHHIIIIGIDBHGEGHGEID@FGCHGIIIIIIGIIEGGGGGGIIGEII<FDGHGIIIIDDHFFHFDEFFFFCACCCCECBBBCBACCCCC
@509
AGAATCAACTGTGATTCCTGAATCTACAATAATGAGAACTCTACATAGTGGAGAAATAACCAGTCATGAGCAGGGCTTCTCTGTGGAACTGGAAAGTGAA
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJIIIIIIJJJIJIJJJJIIJJJGJJJJJJJJHHHHHFEFFFFEDEEEDDDCDDE
@50A
AACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJGIJJJJJJJJJJJJJJJJJJGIIJJJJJHJJJJJJJJHHHHHFFFFEEEEEEEDDDDDDDDDDDDDDDDDDD
@50B
CTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGC
+
CCCFFFFFHHHHHJJJJJJJJJJJIJJJJJJIIJJJJJIJJJJIJJJJIIJJJJJIJJIJJJJJJHHHHFFFFFFEDEEEEEDDDDDDDDDCCDDDDDDD
@50C
CAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCAC
+
CCCFFFFFHHHHHIJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJHHHHHFFFFDEEEEDDDDDDDEDDDDDDDDDDDDDDD
@50D
CACATACCAACGGCGAGGATCACTTCAGCTCTGGCAGTTTTTGGTAGCTCTTCTGGATGACCCTTCAAATTCTCATTTTATTGCCTGGACTGGTCGAGGC
+
@@@FDFFAB?FDDBEHGI>@GHGIIGGGHIGF9CGHH==CHA@EDEEEEE@E@BCC?@ACCCCCCDDDDDDCCCEEEECFCCCCCCDDD=CBD@C@<>B<
@50E
GCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACT
+
B@@FFFFFHHHHGJJJJEEHIJJJJEIJFHIJJIJJGIJJJJJIIJIFJIJJIJGIGGIIJJIGIHGGFFFFEDEECCDDDDDDDDCDDDCDDD@CCDDDC
@50F
CCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGGT
+
:;;;DDDDAFFF<?F;@FE33AD>DCEF?*?DF99?BCF@FFB@F>AAFC7@AAAE@E9BBB?;(6>AA5;ABA5>,,5<(5:@:5(>A>:A(9?B<>&0
@50G
CAGAAACATGGTGAGATTAGTTTTCTAAATGAAGAAGTTAAATCTTTAAAGCAAGAGAAAGAACAAGTTTCATTGAGATGTAGAGAGCTAGAAATCATTAT
+
=;<7AAAA3222<+A++237>B<C,?CB+?BA+?A9A<==ABB<?BBB7A?AB3=)>3>=<;=>BBABBBAAAA>;7AA>AA)))7=2>@(>>@9>=;=;;
@50H
CCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCCACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGGAGCATGGGTGTTTATGGG
+
1==+2+?27?A>+?C<<?,?<>=+3@<7A;ABB>ABA):?=AAA<4;58)(=484>;AAAAA/=1(.6;====:=(9;9(388;?;;987:389
@50I
GACATCTCCTGTGACTCTCACCTCTCAGACAACTAAGACAGATGACCCCCAATTGAAAAGAGAAATAAGGTTAATGAAAAACAGAGAAGCTGCTCGAGAAT
+
??@DDDDDH<?CFFHIIGCFG<BGGHGHHHIHIIDGGHHIHC9BFGHHHGIIBHGFAHEGCFAG>ACGEE=>EHDEEEEECCCC;;?CCCCCCCCBBBBBC
@50J
ATTTGAAGCTGCCATTAAACAAAGAGATGGCATTATAACCCAGCTCACTGCTAATTTACAACAAGCAAGAAGAGAAAAGGATGAGACAATGAGAGAATTTT
+
;??D;D;?3B?DD3CEE@>EFE;;C@FFF9;CE<EFDD9CDBD>9BA?9BEEDE?DDD<B4B(6ADDCC=7@;ACDDAD>9>>AA:>?;>A>AAA?AAAAB
@50K
GCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTC
+
@@@FFFFBHHDHHJJFIBBHHIJJHIEABDFHIJIJ=DGD@GE@FGIHIJJEHAHIJGJFIEGHEHCHDFFEEDCAABDCC@>>@ACDDCDDDDDDDDDD
@50L
AGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACT
+
?@@FDDADHHHHHGG<EHGHICFHGIGEIIIIIIIIIFAE>EC<CHAFEG>C@GIIHHFDBECBD>AACC@;ABBCCCC;CCCCCBCCCCCCC@?ABBBBB
@50M
TATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTC
+
@@@=DDBBFFDFFIEEDAHIEBE?GHGIGG4DB?FA?@DGEIB?FHBBFGHIH@GIIECHGGECHGHEBB?>BCBCCCACA>C@9ABC<@A:A>C@@@4>
@50N
AGCTTTCCCCCTCCTCTGATGATTAAACAGGAACCCAGAGATTTTGCATATGACTCAGAAGTGCCTAGCTGCCACTCCATTTATATGAGGCAAGAAGGCTT
+
?<+4==AD8D8CAEEE::AC:AF9<4AC@188CD=8BDD?9*0?D@DD>/8?BB>BCBE<7=@:A;==;@:AA7.7?@:@@@;@>@BDAA??==9?><=A=
@50O
CAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATG
+
CCCFFFFFHHHHHJJIJGGJJJIJJJJHIJJJJJJIJIJJJJJJJJJJJJJJJJJJJJIJJJJIJIIHHHHFFCDDDDDDDDDDDDDDDDDDDCDDDDEDD
@50P
AAGGAAAGAGGAAGTGGAAGAGAATAAAAAAAGCAAAGCCAAGGAACCTCCTCCTAAAAAGACGAAGAAAAATAATAGCAGCAACAGCAATGTGAGCA
+
@@@DDDDD+AF::CCGCHEFEE:F@HHIIE:F??FHI@92?FCGGHAAEFG;=DCCHHFHB?),3=13>CC@<@CCC>35:9<C<??89?:A:3:4(:
@50Q
CGCGAAGTCAACTTGAAACCTACAAGAGACAGGAGGATCCAAAGTGGGAATTCCCTCGGAAGAACTTGGTTCTTGGAAAAACTCTAGGAGAAGGCGAATTT
+
?@@DDD?AFFBF<FBEGBBECH@BFIIIGIGGE@DE1DD>BF<BBFGGIIG;CHHDAAH<CBBEDE@A;;;>C@ACC>CCBBCCCCCCCC<?C@BB95@?C
@50R
CCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGT
+
@@CFFDFFHHGHGGIGJIIJHIIIIJIJJHJJJGIJIJJJJJJJJIJJIJJJFEHFHHFFFFFFEEEEEDDDDACDDDDDDDDBDDDDDD?CDDDDDDDDC
@50S
GCAAAAGGTGGCTGGAGAGAGATATGTCTACAAGTTTGTGTGTGATCCAGAAGCCCTTTTCTCCATGGCCTTTCCAGATAATCAGCGTCCACTGCTGA
+
@@CFFFDFFFHGGII>EDGEGE@HHIHIIIIGIIGHIDBF3BBECHIIIIAGGIGIIGIIGEH;EHCHEEEHHFDFDDDDEECCAABBB;?CC:@CCC
@50T
CTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCC
+
@@@FFFDFDFFBDHGGEHBDDHGHIJJBHIHIDHGGGGICBGHHGBFGGI>FHIJ@@EHHIEAACFCEEBDCEEEDDBB2=AC3<@<?BDDCDDCAC>?BD
@50U
TGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGAT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJHJJJJJJJJIJJJJJJJIJJJJJJJJIJ>EHHHFFFFDDEEEDDDDDDD;BDDDDDDDDD@CDDDDDDDE
@50V
CCTGGAACTGATGGAGGGAGGAGACCTTCTTACTTATTTGCGTAAAGCCCGGATGGCAACGTTTTATGGTCCTTTACTCACCTTGGTTGACCTTGTAGACC
+
;-(-(2@1):>8=8>=?8@@5@16=1:<>1=<8?>??8>37<5=99)9<1=5-335)686;==95(-:;==(:75;506=((3769</655(6:(42(:<:
@50W
CGGGATGGCCCGAGACATCTACAGGGCGAGCTACTATAGAAAGGGAGGCTGTGCCATGCTGCCAGTTAAGTGGATGCCCCCAGAGGCCTTCATGGAAGGA
+
@@@DDDDD>;F8C8:C3CFB?BEGIDF6@.@@4CDF@FFFF@@EEFF<??D>;@BAC>>B;@=A>AABDB,;A::A<B?<<0<2?@?BABBBABAA>AB8
@50X
TGGACAGTTACCTTATTCAAACATCAACAACAGGGACCAGATAATTTTTATGGTGGGACGAGGATACCTGTCTCCAGATCTCAGTAAGGTACGGAGTAACT
+
@@@DD?DBFHHFHEIIIGIBHEEE<?HEGGDGHIFIGGCEHGHEIEE<DB@GH9DCF88@BBB>BEE@DCCCC;;@CCC?AC-,,5::A:>5=>2989:(4
@50Y
CCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGC
+
@@@DBBDFHGHHHGIJIJIIJJJIJIJIJJJGGFGIIIJIGDGGIGIGGIGGIIIIJJJIIIJIIGHHEEHDFEFFFEE@CBDDBDDDACCDCADDCCCDD
@50Z
CCAACTTCTGACCCACCAGACCACCCACCCAGGGAGCCACCTCCACAGCCCATCATGCCTTCAGTATTCTCTCCAGACAACCCTCTGATGCTCTCTGCTTT
+
@@@DAADFHHGHHIJIBHIJJEECHIIIIJJJID;DGHJJFGGIIDGHGJGEEHGEHHHEHCDFADDEEAC>@CC@CDDCDBB<B9:@CAC:>>CCC@CCD
@510
ACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGC
+
CCCFFFFFHHGHHJIJJIJIFGIIIIJIJIJFEHIJIIIIJGGIJJIJIJJJJJJJJIGJJJJJIEFHFFFFDDEEDDDDDDEDDDDDDCCCDDDDDDDDC
@511
ACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCT
+
CCCFFFFFHHHHGJJJJIJJJJJJJJJJIJJIJIIJIGIJJIJJJJJIBFHIJIJIFIIJJJJJIHHHHHHFFFFDEEEEEEDDDDDDDDDDDDDDDDDDD
@512
GCTCTGGATGGGCGCGGGCTCCTTCTTGCTCACATTGCTGTTGCTGCTATTATTTTTCTTCGTCTTTTTAGGAGGAGGGGCCTGGGCTTTGCTTTTTTTAT
+
;8;=9)):))9>:8((2<57(3)=>?=?<?;=)))/<>;).)8..<))8)))))8==0.919((,,4;;/(:;6'2+5&&086+/5(+62/6<:555&58:
@513
GAAAAAGGAAGCAGAGGAAGAGGATGAGGAACTCTCCAACTTTGCTTACCTCTTGGCCTCTAAACTTAGCCTCTCACCAAGGGAGCATCCCCTCAGTCCTC
+
CCCFFDDFGHHFHJJIIJJJJJGECHIEGEGGIIGGIGHIGIJJJJGIIDHHHJIJGIJIIIIGIIIG?EHHGDEFFFEDEDBDDDDDDCBDCDDDDDDDD
@514
CTGCTCCCAGTTCGGTGGATGGCTCCAGAAAGTTTGATGGATGGAATCTTCACTACTCAATCTGATGTATGGTCTTTTGGAATTCTGATTTGGGAGATTTT
+
@@@BBBBDAFCBHEG+CEFDGGGECGGGG@GE?9DBB>BG@FHGGI@BHG@<FHEIGGG@DHGICEH=;CEC7?=AE>@<CCC@CEEACCD@CDDDBCCDC
@515
CTCTTGAGCTAAAGGATAAATTAACAACTGCTGATAAATTACTAGGAGAATTACAAGAACAGATTGTGCAAAAGAACCAAGAAATAAAAAACATGAAATT
+
CCCFFFFFHHHFHEIGIIJFIIJJIIJJIIIGGJEGHIECHIIGIJIJJJJJJGIJJII@FHGHIJDHHJIJJ<EHFHHFF@DEFDEEDEDDBD>CCDDD
@516
CGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCA
+
@CCFFFFFBHHHHIJJJJJJJJJJIJIIJJIJJIJJJJJJJIJJEIJHGIJJIGGHHHHGFDDDBDBBDDDDDDDDDDDDDDDDDBDDDDBDDDBBBDD
@517
TGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTG
+
@C@FFFFFHHFHGGGHJJJIICGHJJJJJIBHIIJJIJIJIJIIIIJGJJIJJJJJJJJJIJJHHHHHFFFFFFEDEEEDDDDDCDDCDDDDDCCDCCDDB
@518
CACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGC
+
CCCFFFFFFHHHGHIJJJJJJJJJJJJJIIJJJJJJJJJJJJJJJIJJJJJIIIJJJJJIGHFFFFFEEEEEEDDDDDDCCDDDEDDDDDDDDDDDCDDDD
@519
AAGAAAACTACAGAGGAACTAAATGAAGCTTTGTCAGCAAAGGAAGAAATTGCTCAAAGATGCCATGAACTGGATATGCAGGTTGCAGCATTGCAGGA
+
@@CDFFFFHHHHHJJJIIJIJJGJJJJJJIJJGHIJJJJJJJJIIJJJJJJIIJIJJJIGIJIIIEGGIGGIGIEHHGFHFF>@CEEEEECDCCCDDB
@51A
CTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGC
+
B@@FFFFFDHDHHJJJJJJJJJJJJIJJIHIGIJIJJJIJJJJIGGIIGIIJJJJIIJIIIGIJJHHHHFFFFFDEEEECEEDDCDDDBDDCDDDDDCDD
@51B
GCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGC
+
@@@DBFDFFDDDHFIBHEEFHBHEGCGGGGIIIGHGIIEGIGBGIGGGFEGEGCCHAEHEBEEDDDDDABB?BDDDDDCD?ACCACDDCCDBB?BBDDBBB
@51C
GCAGCTTGAAGAACAAGACCACTTATTAGAAGATTATCAGAAAAAGAAAGAAGACTTCACAATGCAAATTAGTTTCTTGCAAGAGAAAATTAAAGTATATG
+
CCCFFFFFHHGHHJJJIJJJJJJJJJJIJJJJJJJJIJJIIJJJJIJJJJJJJJJJJJJJJJJJJJJJIJJJIHHHHHHHFFFFFEEEDDCDDDD>CFEDD
@51D
AAAACACTTGGTAGACGGGACTCGAGTGATGATTGGGAGATTCCTGATGGGCAGATTACAGTGGGACAAAGAATTGGATCTGGATCATTTGGAACAGTCT
+
@C@DFDDBHFHHHHIEGEEHEIE@D?:?GHDF@B?FGFB???B@FGIEGIGIGBCFA@@EDCE?E=CDECDA@CCEECCCACCCCCBCDEEC@CCA?ACA
@51E
GTCCTCCAGGCCTTCCGCCTCAGCCTCCACCACCAGTTGCTCAACTGGTCCCCATTGTGCCCCTGGAAAAAGCTTGGCCAGGGCCACATGGGACAACCGGG
+
=?8A;:2BC?D;<:+2<<AC@3C?A;)1:CC8:D??:?DD?D<B;B?8/8.8B;@;8=87==@(5=;@D??>;>6.(;>555',,,55:5(<3288(+0;?
@51F
GGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATAC
+
CCCFFDFFHGHGHJJJIGJJJJJJJJIJJIJJJGJIJJJJJJJJJJIJIJJJJFIJJJJJJHHFFFFEEEEEEEDDDDDDCDC8ADDDDDDDBDDCDDDED
@51G
CCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGACCCATGGATGAAGGACCAGATCTTGATCT
+
?@@D1:=2=A;<ABBGG@FFACA?E?<9C9C9CCGCFC@?DB?0BD89?BBD?FEFA@F<ABAB8CDD;;;;5==A?A@B@:>@ABBB@B?BAAAB4::@
@51H
CCTCAATCTAGCACAGGGGGTTCCAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGT
+
==1??++@>BBABBB;3+)?1:)177:?;=507/7((...7=9.88/7=)(.=>>AAA37)).7((;>;(;;1>=?>?99=(,'28=388+8;?3::;;9+
@51I
CCCCTTTGTTGGCAGGGAGGCTTCCAGCCTGAAAGCACTCCCAGTTCGGATGCTGGACTTGCAGAGCTGGCTCCTCTGCAAGGACAAGGGTTAGAAAAGC
+
>=1<72<72<++2<?<1<3)+?@3A:7=A>5;*0:?B=*=A=)9>A)<6-56=A>A>27>AA@>3;;3;(5>;=;=?????35,;===;;+298883((2
@51J
CCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGT
+
C@@FFFFFHHHHHJCHEGIIJJJEGGGHEBGCBHIIHHFIIIJJIIJJIGJEHIIICGIGGIJJGHHFFDC@BCB>CDEC@@@CBBDD@?BBBB?B@?<4
@51K
CGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGGCAGCTATACCCAGGCTC
+
@@;DDAD8CFHD?FBAB@@FBCCEHIH9?:CD?GH=BC8FBGGGHCH@F@FG2@C@@D>DCE3?>7);3;>;;;;?@B=A>>C(,5<@AA;@ACCAB?<<?
@51L
TACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTT
+
<<?DBDDDFFB<FF;;<CCI@CFA+A@CEFEFAD@G;???0???F<FD@FAFAFFCEFFI;CEFI;CCAEFDB;?>;;AA>6>ABBBBA<99=;8&0>>>
@51M
TGGCAAGGCCATTGTCAAAGTCAAGACAGAAGGGGGGTCAGCTGAGCCCTCTCAGACTCAGAACTTTATCCTTACTCAGACTGCCCTCAATTCGACTGCCC
+
1:=1?=?A++++<A,,,<CBAC@@A@B3<@7*?<0)50&2888::8=((++(83(++8(83883:?=(+8(88;3:;8::?88999389:?::<;<85338
@51N
GCTGGATGAGATGTATGGGCAGCAGATAGTGCAAATGAAACAAGAATTAATAAGACAACACATGGCACAGATGGAGGAAATGAAAACACGGCATAAGGG
+
CCCFFDFFHGHGGIGIGGEGIIIJGIJJIGIIJJJJJIJJGGIIIJIJJIJIJHIJJJJJJGIJJJJIJJGHHHHHFFFFEEEEEEDDDDDDDDDDDDD
@51O
CTTCCAGCCTGAGAGCACTCCCAGTTTGGATGCTGGACTTGCAGAGCTGGCTCCTCTGCAAGGACAAGGGTTAGAAAAGCAAGTCCTGGGATTGCAGAA
+
@CCDBDBAH?BHHGGBED>>GBFHDCHIEBEGCGIIIE@<?FGDFGHD@FFEHIGGGCGGIICGGEHECC=@?@DCCECBEC?CD@AA>?ACCCCAC@C
@51P
CACGGGCCCCCCGCCGGCGTCAGCGTAAAGCCCAGAGACCTCCTGCTCCTGAGGCACCCAAGGAGATCCCACCAGAAGCTGTGAAGGAGTATGTTGACATC
+
@CCADDFDDFHHDEGIGIIGIHFHDBDDDEDEDDDDDDDDDDDDDDDDCCDCCBDBDDD@BBDB@BDCDDABDDDBDDCCA@CD>CDBBCCDDCDDCDDDD
@51Q
AAATATTACAGTTAATGAAGATCAGATAAAGTTAATGAATGTGGCAATAAATGAACTGAATATAAAATTGCAAGATACTAACTCTCAAAAGGAAAAACTC
+
CCCFFFFFHHHHHJJJJHIIGIJJJJJJJJJJJJJJJJJJJGIIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJHHHHHFFFFFEEDED
@51R
CCTGTGACTCTCACCTCTCAGACAACTAAGACAGATGACCCCCAATTGAAAAGAGAAATAAGGTTAATGAAAAACAGAGAAGCTGCTCGAGAGTGTCGC
+
CCCFFFFFHHHHHJIJIJJJJJJJJJJJJJIJJJJIJJJJJJJJJJJJHHIGIGIHIIIJJJJGIIJJJHHHHHFFFFEEEEEDDDDDDDDBDCC@DDD
@51S
GGGAGACTTCCGGGGGCCTCACTGCTCCTAGAGCCCTCTTCGCTGACTGCCAATATGAAGGAGGTACCTCTGTTCAGGCTACGTCACTTCCCTTGTGGGA
+
@@@DFDDFHFHDHGGIGHGGGIHIIIAGHGHIGIGGIIHFHC>B>CCEEEACCDCCDCDCC<AB(:>A@CCCCDCCC@<?CCB<??BDCCD?CDD>@<<1
@51T
ATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTGTGGACAGCAGAGTAGCTATGGTCA
+
<??DBBB:+AFBHIDHGGEAGHH@GHHI9C@DCFEGHIIIEDGGHGFGGIGGG;BF;FGG@EHGIAA'=9><A?A;-5;>CCB955??::AAC:>>A+:@
@51U
CTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCC
+
@C@D;DDDDHHFHGHGGIGIGCHGJJJFIIIGGGAHGHHIIIGIIJFHGGIIJJJ@GHGJJHG9CEFFB;BCEE=C@B@A@ACCBDDDBDDCDCCCDCDDD
@51V
CACGAGTTCAGCAACAAGAAGATGAAATCACTGTGCTAAAGGCGGCTTTGGCTGATGTTTTGAGGCGTCTTGCAATCTCTGAAGATCATGTGGCCTCAGTG
+
@@CF7@BDFHHHHIGEHICHGGGIIIIIH@FGGHGHHGGIICHBIIIIIIIIGH?CHEDFF>?AECC8?B?CCCCCACCECCCCC@CCCCDCCBBCA@C@C
@51W
CCCCACTGCATCATGCATCTCCAAACTCAACTCATACACCGAAACCTGACCGGGCCTTCCCAGCTCACCTCCCTCCATCGCAGTCCATACCAGATAGCAGC
+
CCCFFDFFHHHHHIIJIIIGJJJIJJJJJJIIJJJJJIJJJJJJJJJJJJJJJJJHHHFFFFFEDEEEDDDDDDDDDDDDD@DBDDDEDDDDDDDDDDCDD
@51X
CACAACTTGAAGCAGAGAATAGCATTCTTAAAGATGAAAAGAAAACCCTTGAAGACATGTTGAAAATACATACTCCTGTTAGCCAAGAAGAAAGATTGATT
+
7?;DDDDDB3D??ABA<AEHCFBHIIIII9CHHG<EHIIGICEDHGG6?DGGGGE@H8</8.=FGIGCGGHEGEHEECEEDBB@CE?CC.>ACCCA>C@AC
@51Y
CGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCT
+
@CCFDFDFHHHHHDIIJIGHIGIIIIIJJIJGGHHIJIJJIDGIJEIIHGIJGGIFDHGIJJIJHEHEHHHEFFFFDCBDDDDDDC>CCDDDCCCDDDDDD
@51Z
ATGAACTATGATAAACTTAGCCGTTCACTCCGCTATTACTATGAGAAAGGAATTATGCAAAAGGGGAGCAGCTAATACAGCATTAAAATTCATTGAAATGT
+
?@@BAD>DHHHDHEGHIIGGIIIIGHBFEFEGHHIGGHEEIIIAFCEGHIEDGGGII@FHGGHI(;BHBBCBCCEEEEDDC?CCCDDDCCCDEDC@CCCCE
@520
CTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTT
+
@@@DFFFDHAD?DBGIJJIGGCHGG@FHGHGIEHGCF;DEHECGIFIEIFEHE<FGGBE?EEBEAAH>@CEDD<ABB?;<<?B@DB<8ACADD:@AD>9>B
@521
CGCCAGCTTTCTGAACCCTGTAACTCCTTTCCTCCTTTGCCGACGATGCCAAGGGAAGGACGTCCTATGTACCAACGCCAGATGTCTGAGCCAAACATCCC
+
CCCFFFFFHHHHHIJJJJIJHIIJJJJJJJIJIJJIJJJJJJJJJIJJIJJJJIJJIHHHFFFDDDDDDDEEDDDDDDDDDDDDDCDDDDDDDDDDDDDDD
@522
GTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACA
+
CC@DFFFFGGHGHJFEEHGGIDGGHIJJJDHJJEHHIJIGHIJHIJJCHIGIJJJIICGHIJJGIIGH@HEFEFFFECCDDDDDDDDDCCCCA>>ACCD
@523
CTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTT
+
@@@DDD8B?FFDF>EFGG;<BGB>EHEFGHGEH@:EFGD;8DDE<BCG>@BD??AEGIIEIH;AEEH<DE?A;AA>>@B959?BBB78@:AC:4><?(5&+
@524
CTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGC
+
@@@DBDDAFFFDFGH@HGBEEGGGGG@GFFHEHIGCHGIGGI>BFEFHEHHGDE@GAH@FIC@DHFHEH;CD;;7>AC>A;3;;>A??<9>CCAA<?AAC
@525
GTCTCGAAAGGCGAAGCGGGAGGAGAAGGGGGGGCCATCTGGGGCACCCCCTCTGCTTAACACCACCTCTGGCAAGGCTGCAAAGAAACCCACAGCTGC
+
(5(-;)41(:<?(22(-894(<=1-...(<'')&&)+(+(3((&&&++(&&)&++2++6((5((((++++8::5:985::86;<<=<<=<9<5<;<===
@526
ACTGGACCTCCCCCACGGGGGGAATCTACCCCAACCCCAACGTCCCCCGCCATCCTAACACCCCCGTGCCTTCACACTTAGGCAGCTACTACTAGAAGCTT
+
?;?B12=AAA:AC6@E:?8100:9=AAA>A?<8=2:0)(+82+8=5<9&-0)(><::A8(+8<&&&)&&2>:>:>443>:+(+(+((+++(+(4(44+>A:
@527
GGAAGACCTGGCTTACATGAACCACATCATGGTCTCTGTCTCCCCGCCTGAAGAGCACGCCATGCCCATTGGGAGAATAGCAGACTGTAGACTGCTTTGGG
+
B@@FDFFFHHHHGJIIIIEGIJIIIGIIIJJIBGIJJJHIJIGEHGGHDGIIJIJIIJGGEEHEFFFBCACEDABBACDDDDDCBAC@CCDDDCDDDDDDD
@528
CTGATGGGCAGATTACAGTGGGACAAAGAATTGGATCTGGATCATTTGGAACAGTCTACAAGGGAAAGTGGCATGGAGATGTGGCAGTGAAAATGTTGAAT
+
?<?AAD;;DD?D+<<AE?CE??A+CBEEEA>EDIDIDDDE4D<BDDBD9DDD9@9BDCECEIDCADDA).);=?6;)6.;>.;@=>>>:;>>>AA;;>:>A
@529
CCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGAC
+
@<@D;DDDDB?FFGIIDGIGGIGIIIIEIGGGCEH:DGHGCGBFH9DFEEB=CBF;FFHGGAC@.=C;?CEEFFDD:;6>;=;A?@=8;;?BC@@C@CC
@52A
CTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACC
+
?@@BADDD<FDFFIIIIIJIIJDGGEDGGGHIAFCFCGHIIG>FHIG5;=CGIIJIIHE'9B;@A>>;CB3;@CCADCC(5>>>@?BACCDCC>ACDD@CD
@52B
CGGGCCCTCCGTTATTACTATGATAAAAACATTATGACCAAAGTGCACGGCAAAAGATATGCTTACAAATTTGACTTCCACGGCATTGCCCAGGCTCTGC
+
CCCFFFFFHHHHHIJJJJIJIJJJJJJJJJJJJJJJJJJJJJJHIJJIIJIJJJIJGIIHGHHHHFDFFFFEEDEEEEDDDDDDDDDDDDDDDDDDDDDD
@52C
GAGGAGGAGCGAGCCCAGCGGCTGGCTGAGCTCCAGGAGCAGCTCAAAGCCGTGCACGAGCAGCTTGCAGCCCTCTCTCAGCCCCAGCAGAACAAACCAA
+
C@@FFD<DDHDHHIDGGDHGIIFGGHHCGIIIHIIHG?@GGHEC>ACFBCD>>BD?3==8;=<BACDBDA>A?CB39AC>@A??BBDBDBCC?CCB?BB?
@52D
GCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCC
+
CCCFFFFFHHHHHJJFHIIJJJJJJJJIIJJJJJIIJJJJJIJJJIJIIGJJJJHIIJJJJJJJJJHHHHFFFFFECCEDDDDDDDDDDDDCDADCEEEDE
@52E
CCGGATGGACCCACCCAAGAACTGCCCTGGGCCTGTATACCGGATAATGACTCAGTGCTGGCAACATCAGCCTGAAGACAGGCCCAACTTTGCCATCATTT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJHGJIJJJJIGIJJJJJJJJJIJIHHHGHFFFFECEEEEDDDDDDDDDDDDDDDDDDDDDDDDDDEE
@52F
GAGGATACCTGTCTCCAGATCTCAGTAAGGTACGGAGTAACTGTCCAAAAGCCATGAAGAGATTAATGGCAGAGTGCCTCAAAAAGAAAAGAGATGAG
+
CCCF??DDFFHHAHEHGEHGIIEIIIHIIICECHEIIFFHIIIHIIIIIIHIIIIIIGIIIIIGHIFHGIIBA;CEHFFFDFCECCCCCCCCCCCCCC
@52G
CGTCACATCAACGAGGAGGACACAGTGCCTCTTTCTCACTTTGATGAGAGCATGGCCTACATGCCGGAAGGGGGCTGCTGCAACCCCCACCCCTACAACG
+
BCCFFFFFHHHGHJJJIJJJJJJJJHJIJEHIIJJGHIJJIJIIJJJIIJGIHIJJJJIIIJJJJHHFFDDCDDDDDDCDDDDDDDDD@BDDDDDDDDDD
@52H
CCCCGAGGGTCCTGACGCAGGCTTCCAACCCCGTCGTCTGCACGCAGCCCAAATCCCCATCCAGCACGCCAGTGTCCCCACTGCATCATGCATCTCCAAAC
+
@@@DDDDDD?FHHGAHGEHEHGHIIIIGIHIIA7BFHGG5=@3;:B<BBACCC@@CCBCCCBCCCCC7>B@BCCCCCCBCBBACCCCCCCCCDCACCCCCB
@52I
CTATAACATTACTGCACGCCACCTACTCCTTCATCTACATTGATGCGCCACCCTAGAAATTTCTTCTTTCAACCTTCCCTCTACCCTTATCACTTTCACA
+
0((--.))):9))):))((;35@<;<>;).193)).))))))))0)8=?=3('()..):))))))))).3).<==)=)((67;5(((-((,(,(,(7(7;
@52J
TCATTATTAACCACAACAGGGCAGAAAATGTACAGTCATGTGATACTCAAGTAAGCTCTTTATTAGATGGAGTTGTGACTATGACAAGCAGGGGTGCTGA
+
CCCFFFFFGHHHHJJJJIJJJJJJJJJJJJIJJJJJJJJJIIIJJJJIJJJGHIJJJJJJJJJIJJIIJJGIGIIIHHHGHHFFFFFFDEEDDD8=BDCD
@52K
AGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACC
+
CCCFFFFFHHHHHJJJIJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJIJJJJIJJJJJJJIIHFGHFFFFEEEEEFDEDDDDDEDDDDDDDDDDDDDD
@52L
CAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTC
+
@@@DAADDFFDB;BFEEGEHA?F@CFG@FH?EABCAG<B:B?DC>DGHGCDFGHFGGB@DHIEE>EHC>?C>>@BAACAC;;>CC:C5??<>CBCCCBB@A
@52M
ATCAACAAGCTCCCCGGCGAGAAGCTGGGCCGCGTGGTGCACATCATCCAGTCACGGGAGCCCTCCCTGAAGAATTCCAACCCCGACGAGATTGAAATCG
+
@@@DFFFFGGHFHHIJIII<GDFHHIIGIGIIGHHFDCDDDDDDDDDDDDDCCDCBBBBD5?BAB@BCDCCACCCDDCDDDDDBDDBDB@BBDDDDDCDD
@52N
CTAGATGTTAAAGATGACTGTGGCCTCCAACTAAGGGTCAGCGAGGACACCTGCCCACTGAATGTTCATTCTTATGACCCCCCAGGAGAAGGCAGGGTGG
+
@CCDDFFDHHHGFHIGGGIEIGAEHIHDHIHIIEGGIHIGGGIIIIIIHIIIGHIIIIEGIHGGHEGHFD@CFFEACAEABBDBBDBBDDCB@BB@DCBD
@52O
CTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJIJJJJJIJJJJJJJJIJJJJJIJJHHHHHHFFFFFFEDDDDDDDDDDDDDDDDEDEDDDDDDDDC
@52P
GTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTAC
+
CCCFDFFDHHHFHJIIJJJJJJHIJJEGIJIIGHDDGGIIIJHHHIIJJJJDGGHEHEGHHGIIIGHHGHGFFD@CACAEBDDDDDDCCDCCDDCDCDDDD
@52Q
GGAAAGCCTACAAATTTATTAAGGGAAGAAGAATTTGGTGTTGATGATTCTTATTCTGAGCAAGGAGCACAAGACAGTCCGACTCATCTAGAGATGATGG
+
@@@FBBDFHFHHHGGGIEHGGI@FHIGE<FGGIIFIII;C?DHGHHG>GIIIGCGGEHIIEHHIGEGIICHEEA>EFFFFFD>@BCDDDDD@C:>CCDCD
@52R
CAGCAAATTAATGACTTTACCCTTCCTGATGTGAACCTTATTGGGGAGCATTCTGATGCAGCAGAGCTTGGAAGGATGCTTCAGCTCATCTTAGGCTGTGC
+
@C@FFFDFHHGHHHJIJJJJJJJJJGGHIIIIGIGIEHJHIHIIIJJJGIJJJCIIIGGHGGIC@GIJJGHHFFFFFFFEEEECDCDDDDDDEDDDDDBCC
@52S
CGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCA
+
B@BDFDFFHHHHHJJJJGJJIIJJJIJJJJIJIJJIIJJJJJJJJIJHIIJJJJJHHHHHFDDDDDDDDDDDDDDCCDEDDDDDDDDDDDDDDDDDDDD
@52T
CAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGG
+
@@@DFFFFHHGHBGDHGIIHGGIIIHIGIIDIIGGEGEIIIIGHGIIIGHIGIIIIIGIIIGIHFHHCEEFFFFEEEEE>CCCCDDDDCDCDCACBDDCCC
@52U
ACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACG
+
CCCFFFFFHHHHHJJJJJJIJJJJJJJEHJJJJJIJJJJIJJJJJJJJIJJJGGIJIHIIJJHHHHFFFFDEEEDEEEDEDCDDDDDDDDDDDCBDDDDDD
@52V
AATTACATGCGGTAAATCTCATATTTTCTTCTGGACCTGGAGCGGCAATTCACTAACAAGAAAACAGGGAATTTTTGGGAAATATGAAAAGCCAAAATTTG
+
@?@?BDDD>FFHH@FBBHEHFHDBEHF<AFDHHBFGBHGEAB;?DG<@F@@F@EEEHIHHFHE@DEECCAABACCCBBB?A?CC>;:@>@CBBCCC?CCCC
@52W
GTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTAC
+
@@BFFFFFGFHHHJJJIJJJJJIIJGHJIJJJGJIIJJJJIJIIJJJIJGIJIGIIJJIIJCHHHHHHFFFDEDEEDEDDDDDBB?BDCDDDDDDDC@DDD
@52X
TTCGTGGTGATGGAGGATCAACCACAGGTTTGTCTGCTACCCCCCCTGCCTCATTACCTGGCTCACTAACTAACGTGAAAGCCTTACAGAAATCTCCAGG
+
@@@BDDD=AD?FDHGHBHIIGIIIICHI9?<DCFHGEGIEHIIIIGBHFEFCECFFFDEEEEDDCDDDDDDDDDDDD@BC@C?CDDCDDCDDDCDDDDDD
@52Y
CCTCTACAACCCCACGTCAGAGTGTGGGATTCTGTTACTCTATCCACACTGCAGATTATTGGACTTGGCACTTTTGAGCGTGGAGTAGGATGCCTGGATTT
+
CCCFFFFFHHHHHJJJJJJJJJHHGHIJIIJJJJJJJJJJJJJJJIJJJJJIIJJJIJJJJJJJJJJHHHHHFFFFDDEDBDD@DCCCDDDDDDDDDDDDD
@52Z
GAGCAAGATGCGCATGGCCACCCCGCTGCTGATGCAGGCGCTGCCCATGGGAGCCCTGCCCCAGGGGCCCATGCAGAATGCCACCAAGTATGGCAACATG
+
@8=DDDDDFFDAFG82C?F;FFAG:)06@B*0??DFI2A;@';;@??;AEDD=8=?65;?;?88<23=>B8A3>>4>3::@A>AB1(8++(++2>A123:
@530
TTTAGCATTCTTGGGGAATGGAGATGTTCTTACTGGAGACTCAGGTGGAGTCATGCTTATATGGAGCAAAACTACTGTAGAGCCCACACCTGGGAAAGGAC
+
@@@DDDDBF?AAF@D@11A:CEFFC<EFHIC>FGBD9?D;?*:BD?0008BD>DF)8BC<=48C@==2@CFCCF;A;;;;@D72;=;???>>???A@<<??
@531
GGGCCCCAGGCAGTTTTATGATGACACCTGTGTTGTCCCAGAAAAATTCGATGGAGACATCAAACAAGAGCCAGGAATGTATCGGGAAGGACCCACATACC
+
?@<=D<?DFHDDDHIIIBHECHIEIHE?GEIBHHGF>FHIIIGCHGHIHHHIIIGIGGIIIHEIEGHHD@@EDDDCBCE>BCFDDDDDDBBB?@BBDDCCC
@532
CACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGG
+
?@@ADF?DHH?HBGEGIIIII<>FCFGHGIIICIIFIIGGGIGGIIIIIHIGGICCGBFG@E==CHGIGEFFEDFFBECBECCA@CCCCCCCACCCB@BBB
@533
GGACAGAGTAACTACATTTATCCCCAGGTACCGGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACAC
+
1+1A1++2CFDFF>FB2<AC,AEFCBB8AAFD))):D6688B8BAF3=CEDEIC(7=AB>;77)6(6;@B;=(5>B?ABB?@A?B(8(:44>:(:(+:@3
@534
GTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCC
+
CBCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJEHJHHHHHFF@BDEEEEEEDEEDDDDDDDDDDDDDDDDDDDDDDDDDDD
@535
CAAGCCCTCGAGCAGTTATTCCCATGTCCTGTATAACCAATGGAAGTGGTGCAAACAGAAAACCAAGTCATACCAGTGCTGTCTCAATTGCAGGAAAAGA
+
?@@DDFFDFDHHHIIFGGHFHIG@FG?BB*C?DHIIEICDHBHBGE9BE9B?FIG>FBAGAF@CHGEAECEEE>DD@@CEA;@>@CCCDCDCDBDBDD?8
@536
GCGGACAGGGCCAAAGGAAAGGAGAAAAAGAAAAAAGAAGCAGAGGAAGAGGATGAGGAACTCTCCAACTTTCCTTAACACTCGGCCTCTAAACTTATCCT
+
::++<0<;<1??;=7=+22@+?31?)*11?13:=A(7=()9>B).=26==;9=7.).).566((;5(;5((((,:3((5((((+2(059;(8(3:::(8::
@537
GAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCC
+
@?@DFDFDFDFFHGGGEHG>FHIIIID<FEIIHHIIIIIGIIIEGGIGEIHHCEHHC@DD?CCEEEA:?BBDDDBD?@ACDA@CDDDCCCC>@DDDDDDBD
@538
AAATTTCCAAGGACGTTTATGAGAACTTCCGTCAGTGGCAGCGTTACAAAGCCTTGGCCCGGAGGCACCTATCCCAGAGTCCTGACACAGAAGCTCTTTCC
+
@@@DBDD;FDF=+CECFA;ACCHE?GE@FEGGFEA?DD@GCCF7?DCEEEEFFE4=CAE@A4=8;?BBB?(:>>>AB9?+:::A:9AAB89@A?>::>>@B
@539
CACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJIIJIIGIJJJIJJJJJJIGIIHJJIIJJIJJJJJJHHFFFDEEDCDDEDDEED@DDDDDDDDBDDDBD@CDD
@53A
GGTGATTTTGGTCTAGCTACAGTGAAATCTCGATGGAGTGGGTCCCATCAGTTTGAACAGTTGTCTGGATCCATTTTGTGGATGGCACCAGAAGTCATC
+
?@=BDEFDHHHCFFHIEIGJIIGGHIGIGGCHHGG>DG?CCB?@FGIIGH@?FGG>FHIIJJIJFHGIGGJJBGEEHHEHFFFFDEECDB?@CD>CDDD
@53B
TGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGG
+
@@@FFFFFHGHHHJJJJIJBHIJIIJIJJJJIIJIJJJIJJJGIGIIJFHHIIJHHHHFFFDDEDEDDDDDDDDDDDDDDDCCDDEDCDDEDCEDDDDCDD
@53C
TGAAGAAATAAAACAGGTAATGGGGACAGTCGAAGAACTTCAGAAGAGAAATCATAAAGACAGCCAGTTCGAAACTGATATAGTACAACGAATGGAACA
+
@?7B=>B8=AC<DGIC3AACCDCHIEICG9EGEH8@BF@G?FEEHG<?89BA)=BCBFC@AFC;@=C=A;==BD<>>A6;;A@(5@:@(8<@BC@:A:?
@53D
CAAAGCTAGGGAACCTATGGACAGCCCACTGATGTCAGATATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGAC
+
=+=A=3=>+?A77<AB3?AAABB=AAC=ABA977A*:=*::?ABBBAAAAA;7>>A=>2>3AA>)(7=A9>A@@@@9==',7=>???????7:88:??;+
@53E
ACCTGGCTTACATGAACCACATCATGGTCTCTGTCTCCCCGCCTGAAGAGCACGCCATGCCCATTGGGAGAATAGCAGACTGTAGACTGCTTTGGGATTAC
+
@CCDDFFFFHHHHGHIIJIIJJJJJJJHHHHHHGIIGJHJGGHIJJFEABFHJEEGIEGHHHDFFFFFDAACCCCACCCBCC>ACDDA@CADDDDDDDCDC
@53F
TACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCT
+
CCCFFFFFHGHHDGIIIJJIIDFHGIJFJGDIGIGIIIIIIJGJIGFBHEGIFHHFH@CBEFEEECEDEDDDDBDDDDDCDDDED@CC>BDBBDDDABBBA
@53G
CTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCT
+
@@@DDDDD?FFFHIGGG@GGHEBFGHGDGGGGEGBDAGHD<AHEFH7@DCHEHE=AAE@CDD=A3@C>CC;@;C>CCCB?9?B@B??AB@ABCCCCCECC9
@53H
GCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGC
+
?<?DD<?2,2AD<CEEBDCEIICCCAED:?BEBD?CDDDIII9DADDDEIAD@ACD@A@CECDCDCADDDDD@A>>:>>AAA5>AABDADAAAA???<9>>
@53I
CCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTC
+
??<B=ABAA2CFAEBFG@FGB;DFCDF??BDC<GEFCGEEGD?DBGC@@F9=<=BFGECEIEEFFFAA95766;A>;>>5;>;A?@>>>AB>@@BABBB?>
@53J
TGCAAACATATCAGATCCGAACTACACCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATGACATCTCCTGTGACTCTCACCTCTCAGACAACTAAGAC
+
@@@FBDFDHHHGGJIJGGGIGIIGIIIJJJJJIJIIJGIFHGGIIJIJIIIIIJJJIGGEIJJGIIIIIJJHHHHHHFFFFFEEDEEDDDDDDDDDDDDD
@53K
GATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGC
+
<;?D;ADD1CCFACEFBFFH>DEHHFIIIIIE@FGIIEGFF4*9BFFEEDF=8=B=C4C@@F@EEECEEEE3;@B@>>;>;AA=3;;>ABB@B@?B<@BB@
@53L
AGGACAAGTGCAAGCCTATGTCCTATGAGGAGAAGCGGCAGCTCAGCTTGGACATCAACAAGCTCCCCGGCGAGAAGCTGGGCCGCGTGGTGCACATCATC
+
@@@D?DDDFCDFFEGGBHCECHGHIIIIGIIEHI>FFEIGFGEHGEHGGDEGAHHDGGFHHAE?CDECCDB;>B@BCC>@CDDD@B>0<@8?CCDCCDDDD
@53M
GTACGATGTCATGCTGGGGTGCTGGCAGAGGGAACCACAGCAGCGGTTGAACATCAAGGAGATCTACAAAATCCTCCATGCTTTGGGGAAGGCCACCCCA
+
@@@DDDDD?C??<2<AFB:<@CDBBCGE@?D::FB@BBBB=BBB4;4;'?CFF?D@DDB;?=@A>>@ABBB:BBBBBBABBBBBBBB9?<828<@?BB>B
@53N
TGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGC
+
=@@+=BBBFFFF;FGGG>EB9FGGGB@3?CEDDFGGIII?D99BBBD@HBHHGG@DCH>DHGCA7==BDEB=;CCC?@;3;;>C3@:ACCCBB<:?9>?B
@53O
CTTTCTGAACCCTGTAACTCCTTTCCTCCTTTGCCGACGATGCCAAGGGAAGGACGTCCTATGTACCAACGCCAGATGTCTGAGCCAAACATCCCCTTCCC
+
CCCFFFFFHHGHGJJIGIJJJIIJJJJJJJIJJIJJJJGHJJFJJJJJIHIJIIIHHHFFFFFEEDCEEDDBDDBBCDEDDDCCDDDDCDDDDDDDDDDDD
@53P
AGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJHHEHHHFFFFEDEEEDDDDDDDDDDDDDDDDDDDDD
@53Q
CCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCC
+
CCCFFFFFHHHHFHIJIJJJJJJHIJJJJIJJIJJJJJJJJJJJJJJJJIJJJJJJJIJJJJJJGHHHFFFFFEEEDEEDDDDDDDDDDDEDD?CDDDDDD
@53R
ACCACAGCAGATGACTGCAGTTCAGAGGTAAATGGTTGCAGTTTTGTGATGAGAACAGGAAAGCCTACAAATTTATTAAGGGAAGAAGAATTTGGTGTTG
+
@@BFFFDFFHHHHIJJJJIIHHGJHHIIFFHIIJIHIJJJJJIIGIHGHIIHIJJIJIJIJIJIIIJJJJJGHHFHGHHFFFEFDEEEDDDDDDD<?<@D
@53S
CAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAAC
+
@<?DDDDDDB:4DHGEGHEDHG7?<FGCFADAD8CC8D8BBBDDFHGEC?F>FFCEFGCG?CHGC>CHFD;BED@C>CCACA>?BB?BA?AABCBCCCCC@
@53T
CTTGGGGAATGGAGATGTTCTTACTGGAGACTCAGGTGGAGTCATGCTTATATGGAGCAAAACTACTGTAGAGCCCACACCTGGGAAAGGACCTAAAGGTG
+
81:?D=?D@:DFFBFE?<:C:CCFHEAE)C1*:?<;1:BBF09???498D@F>DC=@B=FFAF@EEIF4)7?;=E=??D=B@@BB?BB?<<9(5:>@>>+:
@53U
ATTTTTGGGAAATATGAAAAGCCAAAATTTGTGCAGTGTTTAGCATTCTTGGGGAATGGAGATGTTCTTACTGGAGACTCAGGTGGAGTCATGCTTATATG
+
CCCFFFFFHHHHHJJJJJJIIJGHIJJJDIIFGIIIGHHIIJJJJIJIGHIIJIGHGIJJIGGIIGIIIHHHFHHFFFFFEEE>CDAD5>@ADC@CCDACD
@53V
GGGAGACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTT
+
@@@BDADDFFHHFIJGIEHHIEGDCG?DG?DFHGHJIIIIJJGIIGEFFFFDDDDDDDDDED@ACC@CCCDDCBBDDDDCDDD<BBDDDDBDDDDC@CDED
@53W
TACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJAGIJJJHHHHHBDFFFEDEEEEEDDDDDDDDDDDDDDFDDDDDDDDDDDDDDDDC
@53X
GGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCAC
+
CCCFFFFFHHHHHJJJJJJJJJJJIJJJJJJJJJJJJJJJIIIJJJJJJJJJJJJJJJJIJJJJJJJHHFFDDDDDDEDDDDDDDDDDDDDDDDDDDDDDD
@53Y
CCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGC
+
@@@:BD??FHFHDHGIIEFFCG?<AFEGE<BE:C?CCFGHB>?B9*09DHICAGGHACFGCGC==??C)).;;@B7>A6;;=(5@C?((5(:>>C@<?<?0
@53Z
TGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGAC
+
1=+@+@377@C@=+2?=11?A@<<ABABAB>AABBAB>?A*==AA=77=ABBBBBBBA>3>;3=>556=23;3;=?8;28;8((888;;9:3:78;::
@540
TTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGC
+
@@CDFFBDHFHGFIGGFHIIIGGHCGHGGIIGGBGIDHIGIIIGDA@DGHGHIIIGGHIIEIIEACC?CCFDFFE>@@CECCB?CC?BCACCCB??BBB8A
@541
CCATCCAGCACGCCAGTGTCCCCACTGCATCATGCATCTCCAAACTCAACTCATACACCGAAACCTGACCGGGCCTTCCCAGCTCACCTCCCTCCATCGC
+
CCCFFFFFHHHFHJJJJJGHJJJJJGGIJJJIJJJJJIJJJJIJIJJJJJIIJIGIIIIJJJHHHFFFFFDDDDDDDDDDDDDCDDDDCDDDDDDDDDBD
@542
GAACTCTCCAACTTTGCTTACCTCTTGGCCTCTAAACTTAGCCTCTCACCAAGGGAGCATCCCCTCAGTCCTCACCATGCCTCAGGAGGTCAGGGCAGCC
+
CCCFFFFFHHHHHJJJJJIJJGGJIJIIGGHIJFIJJJJIJIIHIFGIJJJIIJJEHIJJJJJJJJIIEHFHHHFFFFFEDEEEDD@BD<CCDDDDBDDD
@543
ACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGC
+
CCCFFFFFHHHHHJIJJJJJIJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJGHHFFFEEEEEEDDDDDDDDCDDDDEDDDCDDDDDDDCD
@544
ACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGT
+
CCCFFFFFHHHHHJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJIJJJHEHHHGFFFFFFFEEEEEDDDDDDDDDDDDDDDDDDDDDDDDD
@545
CCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGAC
+
????+BDB?<2AACA1<EEE>CBEEI**:CEAD99?DBC??DDECCDDAADCBC<8=A@DCD@7)@?>2(6;?;9?@>;/<?<<=A>>;5;A>A????<<?
@546
GTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACT
+
@BBFFFFFHHHHHIJJJJJJJEHHIIHJJIIJIIGIJJJJGIJJJJJGIIJJJJJJJJGIJJJJIIJEHHFHFFFFEEEDEEDDDEDDDCCCDCBBDDBDD
@547
CAAGAACAGATTGTGCAAAAGAACCAAGAAATAAAAAACATGAAATTAGAGCTGACTAATTCTAAGCAAAAAGAAAGACAGTCTTCTGAAGAAATAAAAC
+
CCCFFFFFHHHHGGHGGIJJICHIJJGHEIIJJJJJIIJIIJIIJIIIJJJIJJJJJJJIJIJEHIIIHHEGFFFFEEEEEDDDEDDCCDDDCDDDDDDD
@548
AGCGGCAGCTCAGCTTGGACATCAACAAGCTCCCCGGCGAGAAGCTGGGCCGCGTGGTGCACATCATCCAGTCACGGGAGCCCTCCCTGAAGAATTCCAAC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJIGJJJJIJJIJHHFFFFFEDDDDDD7@DABCDDDDDDDDDDDDDCDDDDBDBDDDDDDDDDDCDDDDDDEDC
@549
GGGAATTTTTGGGAAATATGAAAAGCCAAAATTTGTGCAGTGTTTAGCATTCTTGGGGAATGGAGATGTTCTTACTGGAGACTCAGGGGGAGTCATGCTT
+
@<@DDDA?A:D:CGHGGFBHCHIII92?99??C:C1?A<D9BBFBGHBGD<FB>DFHH1-(7==E=)==?;=)7?3?>;>9=(>A@A(9?'5+9>>CA:@
@54A
CACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACC
+
CCCFFFEFHHHHHJJJJJJJJJIJJJJJJJJJJJJJJIJJJJJIJJJJJJJJJJJ=EHHFFFFEEECEEDDDDDDEEDDDDDDDDDDDDDDDEDCDDDDD
@54B
GTCTAGAGGAAGAGTTAAGAAAGGCCAACGCAGCGCGAAGTCAACTTGAAACCTACAAGAGACAGGTAGTAGAACTACAAAACAGATTATCCGAAGAATC
+
@@@DDDFFHHHHDGBAGHIHIIGGGGGIIIFBHIDGBHBHGHCHECHHHHHGHDFB;@CCC;CCDD;@C>BDDDDACCCCD@B@CCACCCDDDBBDBCC>
@54C
CAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCAC
+
@@@DDDBDA=<AAD:C?CFACBCEGIIB<9:EFGI?CG@@)?FBF8BF4.=C8(@F@E@EEFEFFFC;BDDD;B?;(;5;;5;AAA9?B=??9<@??<?B1
@54D
CTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGCAGGCATATGGGCAACAAAGCT
+
CCCFFFFDHHHHHJGIJIIIIJIIHHGIJJJJJJJJIJJIJJJJJJJJJJHHHHFFFFFEEEEEDDEDDDDDDDDDDDDDDDDDDDDDEDDDDBBBDDDDD
@54E
CACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGAC
+
@@@?DEFFHGHFBEB@FGHGIIIGG<DB9DGCGIIGHEGBDHHEEHGGHIICG@GIIIEHHHHHFFEEBBCC;;?CCCCBCBBCCCBBCCCCCC>@CCCCC
@54F
CTGAGCCCTCTCAAACTCAGAACTTTATCCTTACTCAGACTGCCCTCAATTCGACTGCCCCGGGCACTCCCTGTGGAGGCCTTGAGGGTCCTGCACCTCC
+
@@@FFBBDHFHFDIJGIHIH@DFFGEDHIJGHGG>GEDBDBFFHGBFHGGGHEFDHHDHHIIB=BBBCCCDAA>AC;?B@BDCCCCDB<AA>CCCDC9<A
@54G
ATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCA
+
;?@DDDEFDFHAHEHDFEHGGIGIIGIEIHGG<DHHIGCFEGH>FFECG>GGHIGGFHF<?BCCECCCCC@:>>ACCA><AA?9?85?BBBB@C:>CBBC
@54H
CTGTGACTCTCACCTCTCAGACAACTAAGACAGATGACCCCCAATTGAAAAGAGAAATAAGGTTAATGAAAAACAGAGAAGCTGCTCGAGAATGTCGC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJIJIJHIJJJJJJJJGJJJBHJJJGHJJJJJIIJCHIIJJJHHHHHFFFFEEEEEDDDDBDDDDDCDEDD
@54I
CCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGTAGCAGAGTTCATTCCGACAGGAC
+
CCCFFFFFGHHHHJJJJJJJJIIIJJIJJJJJJIJIIJJJIIJJIIJIJJIJIJJJGIJIJIFIJJHHGGHEDFEDD';BCDDCDDEDEEEEDDDDDBDDD
@54J
GTCAATATTGATGACTTGATTAGAGACCAAGGATTTCGTGGTGATGGAGGATCAACCACAGGTTTGTCTGCTACCCCCCCTGCCTCATTACCTGGCTCACT
+
@?<7?;DA:CFBB<FDGCAHHEHEH?EFC=C?ACBFEFDDE:0*?9?BGGD;FH<CG;FHGG.=:@@DEA<E;?CEECBBB<@BCCC@:A@::AB8?CC:A
@54K
TTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGC
+
@?@DDD?DHFAFFBFAEGFBFEHECGGCHIHIIGEIIGAEHIIGGGD@DGGGIDEG@FEEHIIEEA3?BDEEBDC6>>CCCBB;=A<A:@@AABBCBB22<
@54L
GCATGGAATTTAAACTGATTGAGCCTGAAGAGGTGGCCCGACGTTGGGGCATTCAGAAAAACAGGCCAGCTATGAACTATGATAAACTTAGCCGTTCACTC
+
@CCFDDDFHFHHHJJJGGIGGDDGIJJIIJHGICFGDGEIIIIGHIIIJIEHHFHFGHFFFDDED@DBDDCDDCDEDDCCDCDDDDDDDD@CDDDDDDDDD
@54M
AAAAACTCAAGGAAGAACTAGGACTAATTTTAGAAGCAAAGTGTGCTCTACAGAGACAGCTTGAAGACCTTGTTGAAGAATTGAGCTTTTCAAGGGAAC
+
=?84=::D<DCDAAEEDEI3A?+CC92CCEE?C9?D*1?1::9:??09BDDDBD39/8BBB>@@@AADAEDC=?D==;CAADDD>A;>@@5;5>A?255
@54N
TTTCTCTTCTCTCTCTTTCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATG
+
@@CFFFFFHHHHHJJJIJJJJJJJJJJJJJJJJJJJJJJIIIIIJJJJJJIJJJJIJJJHIJJJIJIJJIJJGHHHHFFFFEEEDEDDDDDDDDDDDDDDD
@54O
TATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTC
+
CCCFFFFDHFHGFJGGHIJGIJIHHIHIIIGGIIJJIIIIIIGGGEHGCGHGIIGJIGIIJIGGGIIHHFFFFCCDCEDDCDDD@CAAAC?DCDDDACCC
@54P
ATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCC
+
?@@DDD>DFFFF>@C2+ADFFFIFIFC9BFCFEFGD9DGFFF;BFFI6@FF?;FFIIB>EDCFEI:=DAE@ECE@BBBDDCCCC;@>;=BBAAABBBBBAB
@54Q
GTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACT
+
CCCFFFFFHHHHHIJJJJIIJJJIJJJGIJJIJJIJIGIIJJJIJIIJJJJJIJJJJIJJJJJJJJGHGHHFFCDDDDDDDDDDCDDCDDDDDDDDDDDD
@54R
TAAAAATAGGTGATTTTGGTCTAGCTACAGAGAAATCTCGATGGAGTGGGTCCCATCAGTTTGAACAGTTGTCTGGATCCATTTTGTGGATGGCACCAGA
+
CCCFFFFFHHFHHJJJJJJJJJJJJJJJJJJJJHIIJIJJJJJJJJHIJJIJJJJJJJJJJJJJJJJJIJIJHHHHHHFFFFFFEECEDDDDDDDDDDDD
@54S
GGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACAC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJIFHIJJJJJJJJJJJJJJJJJJJJJJJJHJJJJJJJJJJJJHHHHHFFFFFDDEEDDDDDDDDDEEDDDDDDD
@54T
CTCTTGAGTCACGAGTTCAGCAACAAGAAGATGAAATCACTGTGCTAAAGGCGGCTTTGGCTGATGTTTTGAGGCGTCTTGCAATCTCTGAAGATCATGTG
+
@CCFFFFFHHHHHGIHIJJJJJJJJJJJJJJJJJJJJJJJIJIJJIJJIHIJIJIHHFFFFFDDDEEEEDBBDDCDDDDBCDDDDCCDEDDDDDDDDDDCD
@54U
CAGAGGCCTTCATGGAAGGAATATTCACTTCTAAAACAGACACATGGTCCTTTGGAGTGCTGCTATGGGAAATCTTTTCTCTTGGATATATGCCATACCCC
+
@@@ADDDDFFFF?GA3EDC9;EFEHEHG@FH@EHGDEGI3DHI@H<D0B@DEEHGFH888BFIGA7=F@DCCAE>==?C3;B@736;;@CCDCCCCCCC@A
@54V
CTGTGAGTAAAAGTCAGACGGAAGCCAATGAGCCGGAAGAGATGGAGAAGATGAAGAAGGAAGAAGTGAAAAAGTATTACATAATGGAGATATCCACTT
+
-(-<())..6:?>:;:)))28=@(:().)).2.:(7(=636))97).93)))..:9)))6(83>)))..;38==(9(-((---:=0(,5;55;2((+82
@54W
CAGGTGGTCGTACAAACTGCATCAGGAGATATGCAAACATATCAGATCCGAACTACACCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATGACATCTCC
+
@@CFADDAFHFHHJIIJJJJJIJJJFGEGIJJJJJIJIJJJJIIEHIIHIGIJJJJJJIJJJJGHHHHHHFFEEFFEDEEDDDDDDDC?BCDDEDDDDDDD
@54X
GATGTGGCCCCGCCCTCATCCAGCGACAGCAGCAGCGATAGCTCCTCGGACAGTGACAGTTCGACTGATGACTCTGAGGAGGAGCGAGCCCAGCGGCTGGC
+
:+1=42B:??8@DEEADE99CBDDDDDDII39BBDDDDDAA;)?ACC>DD<>?;>>>AAAA;=958?>A>>>>>::>><:<><??9)5;;?<>>33.059>
@54Y
CGAGGAGAGACAGAAGAAGCTGGAGGCCGGCAAAGCCAAGCTTGCCCAGTTTCGACAAAGAAAAGCTCAGGCGGATGGGCAGAGTCCTTCCAAGAAGC
+
:?;BD@BDADDB>+<;A3CA:9;88;E;8?6)79?D88B@CC@@@CEC@777?AD=?@3;3>??;=;>A>3589999><<9&22+:>A::AAAA<39>
@54Z
GGAAGCGAGCTCTAGCTGGAGGTCCAGCCCCTACTGAAAAGACACCCCACTCAGGAGCTCAACTTGGGGTCCCCAGGGAGAAACCCCTAGCTCTGGGAGT
+
@@@DDFDDFHHHFGHEIHJHIFEHFGIJGGHIJJJIJJJJJIIJJJJJJJJJIJHHFFBFFFCEEEEDD?BDDDDDDDDDDDDDDDDDBCCCDDDDCA@8
@550
GCCAATATGAAGGAGGTACCTCTGTTCAGGCTACGTCACTTCCCTTGTGGGAATGTCAATTACGGCTACCAGCAACAGGGCTTGCCCTTAGAAGCCGCTAC
+
CCCFFFFFHGHHHJIIEGHIJJJJJJJJJIJIJJJHIIJJJJIIIIIFHIJJJJIBGHIJJIIJJIGGHHFFFFFDDCDDDDDBDDDDDDDCDDCBDDBBB
@551
GGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATC
+
@<?DDFFFHHHHHIIIIICGGEHIIIIIIIBHIIIIGI<FFGIIIIGIIGFIIIIIIIGCEEEHGFB?AEDCCDDBCDCDACBBDDDDDCC>ACCCBBDCD
@552
GCAAGATAAAAATCCATACAGCTTTCAGTCAGATGTATATGCATTTGGAATTGTTCTGTATGAATTGATGACTGGACAGTTACCTTATTCAAACATCAAC
+
CCCFFFFFHHHHHJJIJJJJIJJJJJJJJJJJHJIIGGJJJJJJJJJJJHIIIIJJIJHIJJJIJIJJJJJJJJJGJJIIJJJHHHHHHGFFFFFFEEEE
@553
GTCGGAGGAAGAGGACAAGTGCAAGCCTATGTCCTATGAGGAGAAGCGGCAGCTCAGCTTGGACATCAACAAGCTCCCCGGCGAGAAGCTGGGCCGCGTGG
+
B@@FFDFFHHHHHIJJJJJEHIIIIIIJJJIIGIIIIIIJGGGHJJJJJJGHHHHHFFFFFDECEECDDDDDDDDDDDDBB@B>@@BCCCDDDBDB@DB>B
@554
CCAAGCCATTATGATGATGGAGGAATCTGTTCAACATGTTGTCATGACAGCCATTCAAGAGCTGATGAGTAAAGAATCTCCTGTCTCTGCTGGAAATGATG
+
CCCFFFFFHHGHHJJJJJJHHIJJJJJJIJJJIJJJJJJJJJJJJJGIJIJJJJJIGIIJIJJJFHIGHGIJJJIJJHHHHHHFFFFFFDEEEEEDDDDDD
@555
GTTGAAAAGGATACAACAGAACTCATGGAAAAACTTGAGGTAACCAAGCGAGAGAAATTAGAGCTGTCACAGAGACTGTCTGATCTTTCTGAACAATTGA
+
C@CFFFFFHHHHHJJJJJJJJJJJJIJJJJJJIJJJJGJIGHIIJJJJIJIJIIGIJJJJIGJJJHHHHHGFFFFFEEEEEEDDDEDDDDDEDDDDDDDD
@556
CCTGGCTGCCCGGAAGGATTTCCAGAGGGAGGCCGAGCTGCTCACCAACCTGCAGCATGAGCACATTGTCAAGTTCTATGGAGTGTGCGGCGATGGGGACC
+
CCCFFFFFHHHHHGIJIFGIJIJJIGGIIIIIJIJIIIJJJEHIJJIHHHFFFFFEEECCDDDDCDDDEEEEDEDEEEEED@B@A>CCBDDDBBBDDDBDD
@557
GCGAGCGCAGGCGGCCCTGGCGGTCAACATCAGCGCAGCGCTGGGGCTGCAGGACGGGCTAAGGACCAACCTGGGGCCCAAGGGCACCATGAGGGTGCTCG
+
;;=A+?<=)07<?:))0(9AA'=A:A;>@)7>3;,,',8'75;1()7&)888<0()&))&(38;:8(+2()889;-&5;0;<=2(2++(((4(((+(2(+(
@558
GAAAAAAGTGTCTCCGCACCAAGAAGTCACTCAAAGCCATCCACCTGCAGTTCAAGAACTGCACCAGCCTGCACACCTACAAGCCCAGGTTCTGTGGGGTC
+
@?@D?DAA<AA<?A<EEG1FEEGIFI:DDF??DGF?GBGDF@FBF@===CFIIIIDFI@===A=?@?B?@@C@@B@@;3?B@:9?B??<::@AB3:@<900
@559
CAGCAATGTGAGCAAGAAGGAGCCAGCGCCCATGAAGAGCAAGCCCCCTCCCACGTATGAGTCGGAGGAAGAGGACAAGTGCAAGCCTATGTCCTATGAGG
+
@@@FFFFFFAHFGIJJFIIJJJJJEHIFJIIGJIJJJJJJIIJJGIIJFIGIGEHHHEFFFFDCDDDDDBDDDDBDDDD>ACCDDDDDCDDDDEDDDDDCC
@55A
CCCCTTCCCACCACAAGGCTTTAAGCAGGAGTACCACGACCCAGTGTATGAACACAACACCATGGTTGGCAGTGCGGCCAGCCAAAGCTTTCCCCCTCCTC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJHHIJJJJJJJJIJJJHIJJJJJJJJJJJHHHHFFDFDDEEDDDDDDDDDDDDDDDDDDDDDDDDDDDDDD
@55B
CTATGAACTATGATAAACTTAGCCGTTCACTCCGCTATTACTATGAGAAAGGAATTATGCAAAAGGTGAGCAGCTAATACAGCATTAAAATTCATTGAAAT
+
CCCFFFFFHHHHHJJJJJJIIJJJJJJJJIJJJJJJGIJGIJJJJGHIJIJJIIIGIGIIGIGJHI@EHIGHHHFFFFFFFEEEEEEDDDDDCDEFDCDDA
@55C
CTTGGCCTCTAAACTTAGCCTCTCACCAAGGGAGCATCCCCTCAGTCCTCACCATGCCTCAGGAGGGAAGGGCAGCCAGAGAGCATCCCACCTGCTCCCTG
+
-((8@)9>?1>)96)2)>948@1><8??53;515/.)).==)<1<6)66<87:8)=:?;;9;?;9?'99=6;(9;5;7;8;(,(2,,++22&26(:((22:
@55D
GTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTAT
+
@@@FFFFFHHHHHJJJJJJJJJJJJJJIJIJIJJJJJGIIJJJJJJJJJJJIJJJJHHHHFFFFFEEDEEDDDDDDDDCDDDDDDDDDDDDDCDDEDDDDD
@55E
GCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTAT
+
@@@DD;:A8DHDF@<FGGEH4CEHC:CFHEH<CGG@AD<CFBDFDFHBGHII>>AFF@FHEHGCA>7=;)7==CB@BEECCCA@CC?@>@8<AC?CCBCCC
@55F
GTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACT
+
<@@BFFFFHFHFHJGIIJJIJHHIIIJJIGIGIJJJJJJJGJIIIJIJJGIJIJIJIJIJGIIGJJIJHHHGFFFFEEEDDECDDEDDDDDDDC?ABDDDD
@55G
TGCAAACATATCAGATCCGAACTACACCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATGACATCTCCTGTGACTCTCACCTCTCAGACAACTAAGAC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIIIGHICHIJJIJIJJIJJJHHHHHHFFFFFEEDEEDDDDDDDDDDDDD
@55H
GTTTGCGGACATCAGCAAAGACCTGGAGAAGATGATGGTTAAGAGGAGAGACTACTTGGACCTTGCGGCGTCCACTCCATCTGACTCCCTGATTTATGACG
+
@<@FFDFDFFHFHJEHEHCGGIGGHIHHGGIGIIJJGGBBHHIGDHIEBAHIIEEGGJGGHHHHHBD<6?B@D?CDDDDDCCDDDDDDDDCDDDECDDDC?
@55I
CCGAGACATTGCTGCCAGAAACTGCCTCTTGACCTGTCCAGGCCCTGGAAGAGTGGCCAAGATTGGAGACTTCGGGATGGCCCGAGACATCTACAGGGCG
+
1??14=ABDDDD:EBA2<A?<FCF@??FDEA<EEDD?DDEID@D=??@D?@(..8BDIA@C6==CAD;7ADAD@88,355=>=???;>?>>4:>:498<0
@55J
GGAAGATAAAGTTTCTTTTGAAAATATGACTGTTGGAGAAGAAAGTAAGCAAGAACAGTTGATTTTGGATCACTTACCATCTGTAACAAAGGAATCATCAC
+
BB<DDFFFFFHFFGIJJJJJJJJJJJJJJJJJIIIJIIIJJIIJJJJJJJJJJIJJIIJJIIIJJJJJJJJIIJJGGGGHHHFDFFDFFEEEEDDDDDDDD
@55K
GTTGCAGTCCTGGAAAATCAAAATAAAACTCTAATAGAAGAGTTAAAAACTTTGAAGGATCTTTATTCCAATAAAAGTGTTTGATTCCTAAGAAAGAAAAT
+
CCCFFFFFHHHHHJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHIJIJJJJJJJIJJJJJIIIJIJJEHHHHGGHFFFFFFFEEEEEDDDD
@55L
GAAAGCGAGAGGGAGACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGC
+
@@CADFFDHHHBFCFHEGIGIIHGGIJHIHGIIIFHFGGCHHGHGFFFDEEECABDDBDDC?BDB@CDDDDDDDACCDDCCCCDDCDCDDC<BBDDDB?BD
@55M
CTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCATCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATG
+
<<;?98886=((9:)..9/((((2(<=??77?=>?1>3=)73.-'==?)).(9>>0.86;(:636==1(739;;(,;78;6<::(::<<5((+82326(8:
@55N
AAACAGGCCAGCTATGAACTATGATAAACTTAGCCGTTCACTCCGCTATTACTATGAGAAAGGAATTATGCAAAAGGTGGCTGGAGAGAGATATGTCTAC
+
@@@FFFFFHGHHHJJJJIJJJJJIJJJJJJJJJIJIIIIJJJJJJJJIJJJJJIIIIJIIJJJJJJJFEHFHGHFFF?CDDEBDBDCDBBDDDECFDEDA
@55O
GTCAAAAATTACAGATTCAATTTCAGCAATTACAGGCTAGTGAAACTCTGAGAAACAGCACTCATAGTAGCACAGCTGCAGACTTACTACAAGCCAAACA
+
C@@FFFFFFHFDDGGFHIHHEHICEHHHJJIEGIGGHGIII>CGH>BHIIIIJJJGGCCHEHIG<CA=FEECAG@@@EEFGHFEFF;;@EEDCB?CCDBB
@55P
GGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCC
+
BCCDDFFFHHHHHJEHIJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJIJJJIJJJJJJJJJHHHHHHFFFFFFEEEECEDDDDDDDDDDDDDDDD
@55Q
GTTTGAAAAGGGCCCCAGGCAGTTTTATGATGACACCTGTGTTGTCCCAGAAAAATTCGATGGAGACATCAAACAAGAGCCAGGAATGTATCGG
+
@CCFFFFFHGGGHIJJIJIJJJGGIIGHIIIIIGIJJJIGHGHIBFHEHIIIJIGIEIIIIJJIGHHHHFFFFBEDEEEDDDDD@DDDCDDABD
@55R
TTTTATGGTGGGACGAGGATACCTGTCTCCAGATCTCAGTAAGGTACGGAGTAACTGTCCAAAAGCCATGAAGAGATTAATGGCAGAGTGCCTCAAAA
+
@<@DDBBD==ACA?FH<E8??FCGGI<?1?:?::?FDDF0?BGC9?D:@64-8@C4)7==AA>=??>?@>CC@AA=@CCAC;:??<BB:5>C:A@>@C
@55S
CTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACAAATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGC
+
=?1BDDDADDD<:CCE;E+AF:CEF=FD9<9*1??;9)0??;?D38B@><@8()8/))87@C26;C>>A;??.)7;(;6;AA>>A5;=(9>>>5(9((+:
@55T
TGACTGTTGGAGAAGAAAGTAAGCAAGAACAGTTGATTTTGGATCACTTACCATCTGAAACAAAGGAATCATCACTTAGAGCAACTCAACCAAGGGAAAAT
+
0(((-26=6:@<9;<<4;6)3=84>>?:7@>>;<?:;<?===>>?<<>>?>1))))0)66.<>16):936))...6);).6)839((6=7(9(((,83;;(
@55U
CACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTG
+
CCCFFFFFHHHHHJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJIIIJJJJJJJIJJJIJJGJJJIHHGHFFFFFFEEEEEEDEDDDDDDDDDDDCDDDDDD
@55V
CTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTT
+
C@@FFFFFHHGGFIJJJJIIEIJIGHIIGHIEGIJJJJJJJGHIGIIJIJHIJJIIJIJIJHHHEHHDFEFFFCBDDDBDBDDDDDDD>CDCDEDDD395@
@55W
CATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACT
+
@@@DDBE<FFHBH=@GGIIHGGGEHGDHHB3CF9:?FC=DBFHC@HIA9BFE>8=BC==C;(=DD>EHHAEFFE@>BCE@CED=A'==?=:@<9>>>CCC?
@55X
GGAGAGCACACGCGTGATCCAGCTGATGCCCAGCCCCATCATGCACCCTCTGATCCTGAACCCCCGGCACTCCGTGGATTTCAAACAGTCCAGGCTCTCCG
+
@@@?+ADDFFHHHH@FEHHEEHFGGGIDGIGEGDDHHIDFHADHIEHGGE>DA>D>EHHECBEDCBBBBBCCCB??B<ACC>@@ACBCCCA>:3?<?CCC9
@55Y
CGAGTGAGCTGCGAGACCTGCTGTCAGAGTTCAACGTCCTGAAGCAGGTCAACCACCCACATGTCATCAAATTGTATGGGGCCTGCAGCCAGGATGGCCCG
+
1:?++2A3CAA<)@E8E?3CAEE:C@EID1?@>DFDBDDDECDE9D@;(8=>C@CDDI=(;=C7;A@)?D@A@A(66.5>?>',8(,5>?><>+(48>A80
@55Z
GCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTAT
+
7?@FDFFEHFGHBGHIIBHDHGHIGGIIHBHIGHIGGIF?DFGGGIBDHGIEGGEFHFEHGEGHEEDHHHEAEEFFBEFEDCBECCBBAAD?ACDDCBCAC
@560
CCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTAT
+
CCCFFDFFHHHHHJIGIGGIGGCHGIIGGGHGDHGIGGHAHGHF?FHIGGEB=88B==CFFIC:C;C=?>7=?BE?@6>CC;A>>CC>AADBBBD@9>B@A
@561
TATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTAC
+
CCCFFFFFHHHHHJJJJJJJIIJJJJJJJJJBGIIIJJJIJJJJJIJJJJJIJIIJJJGIIJJJIJJJHHHHHFFFFFEEEDDDDDDDDDDDDDEEDDCDD
@562
AGTCAAATGTGGGTTATATAAGCTTAATAAATAACTGGATAAATAATTTCATTAAAAAAAGATTATGAAGAATGCTGAAAACAAAAGGTATGTTGGTGACT
+
CCCFFDFFHDHGGIIIGJJJJHJJJGGIGJIJIIIJJJIJJJIIIIIJIJIJJJIIIJJJGIIIIJJGIGHGFHEEFFFFECADEBCD@CCCDEDD<@CCD
@563
GTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCC
+
?@@:DDDDFFFFFF?DBGIIFEFFEFGD>GGEGICFIDFEE?FFFI:FF@FFIIIFEFIEEEFFF@DDDD?@C@@3;?B@::@BEBEBBBBA@A??9:?BB
@564
AAGGAAACCTCAAGCTGAGAAAGTTGATGTGATTGCCGGCTCCTCCAAGATGAAGGGCTTCTCGTCCTCAGAGTCGGAGAGCTCCAGTGAGTCCAGCTCCT
+
CCCDDFFFHFHHDHIIJJIIJJJDHHGGHAFIIIJHGJJF<GIGIIJJIIIIIIIIEHEHICGHEEFFFFEDD;>?BDD?BBCDDDD:ACDCCDDDDDDCA
@565
CCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACA
+
CCCFFFFFHHHHHJIJJJJHHIJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJHHFFDEEEDDDDDDDDDDDDDCDDDDEDDD:CCDDD
@566
GTGAACCTTATTGGGGAGCATTCTGATGCAGCAGAGCTTGGAAGGATGCTTCAGCTCATCTTAGGCTGTGCTGTGAACTGTGAACAGAAGCAAGAGTACAT
+
@@<DDBDBFHHHFIIGHGIFIIIIIHGIIIIIIIGBGIIIGIIIIGEEHGIHIICDHDHEGEHIICHFAEEECEEFFE<C;ADEECCCCCCCCCCA:@CCD
@567
CCGGAAGCACCAGGAGCTGCAAGCCATGCAGATGGAGCTGCAGAGCCCTGAGTACAAGCTGAGCAAGCTCCGCACCTCGACCATCATGACCGACTACAACC
+
@@@FFFFFHGHHHGJIJIJJJGIGIJJIFGGIIIIJGEIIEIJIJHGGIJJJGHGIJGGIIIGGHHHHFFFFDDDDDDDDDDDDDDDDCDDDDDDDDCDDD
@568
CCTGAACCCCCGGCACTCCGTGGATTTCAAACAGTCCAGGCTCTCCGAGGACGGGCTGCATAGGGAAGGGAAGCCCATCAACCTCTCTCATCGGGAAGACC
+
@@@DDDDFHHHHFIGIHGIICGH@DFGHIJIEGIHIIIJIIIJCHIBGHGDDCD@BB@?CCDDDDCD@BBBBDDDDDDCDDDD>C@C:AC@CCBBDBBBCD
@569
CAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCC
+
8?@DBDDDHFHDHBFHFDFFGEGHGHIGGGGHHDGGHIIIEHDGGECHDAGCEHEH?DBCB@DCCCCADCCCBC?B(5:C@>9<??<8ACCBBBC?>AA@?
@56A
TTTGGCAGATGAAGCTCAGTCTCTGAAAGATGAGATCGACGTGCTGAGACATTCTTCTGATAAAGTATCTAAACTAGAAGGTCAAGTAGAATCTTATAAA
+
@C@FFEEFAHHFFEFGGHHHHICCHIIJIIIEDGGABFGBEFGBHIFIIGGGGCGECGI>HIJGIHGIIJJEE3AHHDFEFB>ACC>CC5;>;ACDDDEE
@56B
CACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAG
+
@@@DDDB=ADAD=?EAHGHGFCIBHGIII<GBGGIIIIIFIGHII<FDGHIIG>>FHIGICHHHFFDDEECCCCCBCB?CC
@56C
CTCTACAGAGACAGCTTGAAGACCTTGTTGAAGAATTGAGCTTTTCAAGGGAACAGATTCAGAGAGCTAGACAGACAATAGCTGAACAAGAAAGTAAACTT
+
@@@DDFFFBF<FHIBGGGGEHIIIIGJFGGIJIJHHIJJJIJIGHGJFEGIFICHIJJCGHC>DHGIAHHIGH>EHHF@BFFCCCEDEDCCDDD3>@CCDD
@56D
CCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAAC
+
@@@BD;B>?DDFB<E@<E@F<F:AFD?GH@C?FBDF<G;BGIFFECF<??BBFCBFFCC@@FEB@A6:;7;BBBA@:AA;6;;=5>;>3>:ABABA9<A<
@56E
TACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCT
+
@@@FFFFFGGGHGJJIJGIDIDEEI<BFIGGGG;GDHIIIIFI;AHGCHGEAECAACBBFFFEDECCCEDDDDCDDCCCC;C>CCDDD?<B>?A?A@DDBD
@56F
CGGAAGTTCACTACAGATAGTGATGTATGGAGCTTCGGGGTGATCCTCTGGGAGATCTCCACCTATGGAAAGCAGCCATGGTTCCAACTCTCAAACACGG
+
;(081(=@9<):);4)6)...)9.:484;>1(8.=)@64?0-7)..6)<>;??(5=?83));>;7;>8.:9=0976=7;;;-:(7;=6370;53;:/+&0
@56G
GAGCAGGCGGGCCTGAGGCCGAGTCAGCTGCGCGGGCCCCCGGATCCCCCGACAGAGCGGCGGCGGGGTCTGGCCAGGCGGTAGGCGCTGCCCGGCCGCGG
+
CCCFFFFFHHHGHGGGGHIJEGHIIGHECEEDDDDDBDDDDBD@5@CDDDB5<BB9?><B;<B55>&0&)(+<(2(+885<))0?+)&&&&2(&0&5))&0
@56H
GCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGC
+
@@@FFFFDHHHHHJJJJJJJJJJJJJJJJIIIJJJJJIJIJJJIJJIGIIJJJJJJJJJJJGHHHHHHFFFFEEDDDDDDDDDDEDDDCECDDDDDDDDDD
@56I
ATTGAAACAGAAACATGGTGAGATTAGTTTTCTAAATGAAGAAGTTAAATCTTTAAAGCAAGAGAAAGAACAGGGTTCATTGAGATGTAGAGAGCTAGAA
+
+++2<A=?7A722?AC7=33+3@73+22@C721@=7@BB*?*?=A?777:*0**=*00**97>;3>B77(=8).(...)=373.6)7.5.(((,(;>=;;
@56J
ATTCCACAGCCCTTCCGACCAGCAGATGAAGATCATCGAAATCAATTTGGGCAACGAGACCGATCCTCATCAGCTCCCAATGTGCATATAAACACAAT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJHHFFDDDDDDCDDDDDDDDDDDDDCDDEECDEEEDDDDDD
@56K
TGATCCGCCGCCTCTCCCCGGCTGAGAGAGCTCAGGGACCCAGGCCGCACCAGGAGAACAACCACCAGGAGTCCTACCCTCTGTCAGTGTCTCCCATGG
+
CCCFFFFFHHHHHJIJJJJJJJJJJJJJJJJJJJJJJIJJJJHHHHFDDDDDDDDDDDDDDDDDDDDDDDDCCDDDDDDDDDDDDDDCCDD@CDDDDDD
@56L
CCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACA
+
@@@B?DD?FHHBAFFFGIGFHHICGFIHGEHCFGFGAGHGAHIGGDD>@GHHIGIICFGHEGEGF<BECCCCCCCCCCCBBCB<A>CCCCDCCC>CCCCC
@56M
CCCCGGCACTCCGTGGATTTCAAACAGTCCAGGCTCTCCGAGGACGGGCTGCATAGGGAAGGGAAGCCCATCAACCTCTCTCATCGGGAAGACCTGGCTT
+
@CCFFFFFHGHFHIIJEHIJIJJIJGIIJJIGGIGIGHIIEIJJGIHHFFDDEEEDDDCBDDBDD?BDDDDDCDDDDDCDDDDEDDDDDDDDDDDDDDDD
@56N
CCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCT
+
CCCFFFFFHHHHGJIJJIIIGGJJJIIJJIIJJJJIIGHGIJIJIJJJJJJJIIIJJEIJJJIJJIHHHHHHFFFFFEDDDDDCDDBDDDDBDDDDBDDD
@56O
GCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGC
+
CCCFFFFDHHHHHJIGJJJJIJJJJJJJJJIJIIJJIJJJJJJJJJJJJJJJIJJJJIJIJJHHHHHHFFFFECCDEDDDDDCDEDEECEDDDDDDDDCCD
@56P
CAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCC
+
CCCFFFFFHGHHHJJIJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHHHHFFFFEDDDDDDDDDDDDEDEDDDDDDDDDCDDDDDD
@56Q
CTTTCCCCCTCCTCTGATGATTAAACAGGAACCCAGAGATTTTGCATATGACTCAGAAGTGCCTAGCTGCCACTCCATTTATATGAGGCAAGAAGGCTTCC
+
CC@FFFFFHHHHHIJJIIJGJJJIJJJJJJJJJJJJJJIJJJJJJJJJJIIIDHIHGIJFHIJJJJIJIIHFHHHFFFFFFDDFACEEDDDDDDDBDDDDD
@56R
CAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATAT
+
CCCFFFFFFHHHHJIJJGIIIJJJJIIJJJIJJJJJJJIJJGIIJJJJJJJJIJJJJJJIJJJJHHHHFFFFFFEEEEEDCDDDDDDDDDDDCDDDEED
@56S
CCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTAT
+
@?@DFFFFHFHFFEFG@FFHHGHIGHJIIIGIJEIHGGGIGIIJJJGIJJIJJIIGIIIJFHEHFDDFFDCDDB?DDCCCCDC?BBDDDDDDDDDDDD5<4
@56T
CACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACC
+
@@?DBDFFHDHDFHJJIJIIJIIJIJBGGGDHHGHIJIJGGIBDEHI@DHGHIJEHIJGFHEAGHEEEE@EDFBCDDDDDDDC<ADDEEDEECBDDDDDDB
@56U
ATAATTTTTATGGTGGGACGAGGATACCTGTCTCCAGATCTCAGTAAGGTACGGAGTAACTGTCCAAAAGCCATGAAGAGATTAATGGCAGAGTGCCTCA
+
CCCFFFFFHHHHHGGJJJJJJJJJIIJJJJIIIJJJJJJJJJJJGIIJJFHIJIJIAEHHHHHHHFFFFCEEEEDEDCDDDDDDDDDDDDDDD:CCDDDD
@56V
CCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGG
+
@@@DDFFAAHDHHIJJJIGIIIEGGHDHIIDGHJJEGGIJJGIIGDHJC3@=DGHDHHHGHHFFFF>@CCCCEEDCDDDDDDD>ACA?DABBB?BDBDDDC
@56W
CAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGC
+
CCCFFFFFHHHHHJJJJJJFHIIJJJJJJJGHGIJJJJJJJJJJJIJJJJJJJIJJHIJJJJJJIHHHFFFFDEEDEDDDDECCCDDDCCDDDDCDDEDD
@56X
GCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGC
+
C@@DFFFFFFHHHJIJJIBIGGGGIIHIGJGGGIIGGEFIGDHJJIGIJIEFGHGJJIGHEDFFFEEEDCADDDBBCCCCDDDDCCDCDDCDDDACCDAC
@56Y
GCCTCCGGGAACCGCGGCCCGGAATCGGGGCGCTTCGCCCCGTGCCCCCCAGAATCAAAACCCCGGCGGCCACAGGGCTTGCCTTCCCGGATTAGGCCTA
+
7(((((0(-@(:5-59(((7('-9-)('-''''3,6&&6070&)5(5(7:-2((5((+(3(8(505&&&&05((((((++)(6(((86&&89:/((++((
@56Z
CTCCAGAAAGCAAGAATGCTACTCCCACCAAAAGCATAAAACGACCATCACCAGCTGAAAAGTCACATAATTCTTGGGAAAATTCAGATGATAGCCGTAAT
+
@<@DDFDAD?DF?FGIIIGH<EGEDFCAHGEHHFGIIIIIIDGIAGFHIGIHIGIIG>GHHE;?AAECBCEDBD>AEC?CDDDDACD>@AC5>;CDB@>>8
@570
CACAAATTCGAGCATCACCTTCTCCCCAGCCCTCTTCACAACCTCTCCAAATACACAGACAAACTCCAGAAAGCAAGAATGCTACTCCCACCAAAAGCAT
+
@CCFDFFFGHDHHJJJJGIJJHGIGIGIGHJJGIGIGGJJIJIIGHGIJJIJII@FHIGIHJJJGHFGGHFFDDFEEECCCDD@CCDDDCDDBDDBDBDD
@571
GAAAGATTGATTTTCTTAGACTCCATTAAGTCCAAATCCAAAGACTCTGTGGGGGAAAAAGAAATAGAAATACTTATAGAGGAAAATGAGGACCTCAAAC
+
+++B?B;;DBFFFH<@GAEBEAEG>F@EHH9A<CH4*C?GH@B9:<*0:0:)??A;FC;@'5=C3.).;;??@CAD;A>@C?BBC5(:(::A??55@ACC
@572
AACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCC
+
CCCFFFFFHHHHHJJJJIIIIJJJJJJJJIIIJJJIJJIIJIJJJJJJJBFGIJJJIGIIJJJJJJHHHHFFFFFEEEEEEEDDDDDDDDDDDDDDDDDDD
@573
TGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTAC
+
CCCFFFFFHHHHHJJJJIIIIJJJGIJGIIFGHIJJIIJHHIJJJJJFHIJJJIJIJJJJJHHEGFDFFDEECEDDEEDDDDDDDDDDDDDDDDCCDCDD
@574
TGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGAT
+
@@@DDDDDHHF?FHEEGB:FHGCGBHEEGIHIIGIIIIICGHGHIIGEHIEGFGC;C;C=AEHEEDEBCCA>>ACCCB@BBCA??>CCCB:?>ACCC@CA
@575
GTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACA
+
@@?DFFBBHDFHDIIFBGHHIIIHGEGIICGGIIGIIIGICHIIIIIIIIIIIIGDGHIIIIG@EGDCEEEHFEFFE@BCDDDDDDDDCCCC@CDCDDD
@576
TGTGATTGCCGGCTCCTCCAAGATGAAGGGCTTCTCGTCCTCAGAGTCGGAGAGCTCCAGTGAGTCCAGCTCCTCTGACAGCGAAGACTCCGAAACAGGTC
+
@@@DDFFFHDHFCC<GBG@EE@HIBGE?::F;D?9?B?GHD>GBF@)=@<BBHFHE7;?B@DC:>CECCC@CCCDCC>>>>??B@B5?:>C<<B@@CD?CC
@577
CAAGAAGATGAAATCACTGTGCTAAAGGCGGCTTTGGCTGATGTTTTGAGGCGTCTTGCAATCTCTGAAGATCATGTGGCCTCAGTGAAAAAATCAGTCTC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJIJJJJIJJJJJGIGHIGIIJJGCHIGHFFDDEEEDDDDDEDDDDDDDDDDDDDDDDDDDCCCEDDDDDDDDACDD
@578
AAATGAAGAAGTTAAATCTTTAAAGCAAGAGAAAGAACAAGTTTCATTGAGATGTAGAGAGCTAGAAATCATTATTAACCACAACAGGGCAGAAAATGTAC
+
?::BD;DDAF?ACFHIB?FE@@:CH@FHEB@CDG@GBDGD;GG<??DDG<D?*9BF8?<DDGHCHD@=FA;@DGHGH>D77AHEEE@=ACBB??CC>ADEE
@579
TACACCGAAACCTGACCGGGCCTTCCCAGCTCACCTCCCTCCATCGCAGTCCATACCAGATAGCAGCTACCCCATGGACCACAGATTTCGCCGCCAGCTTT
+
CCCFFFFFGHHHGIIIJJIIJIJJJJIJJIJJIIFEIJJJJJIIIIIGHHFFFFFFECEBCCDDCDBDDDDDDDCDD<CDBBDDDDDDCCBBBDDBDBCDD
@57A
GTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTAC
+
@@@DFAEAF?HHDBHHIIIIIIBGGBGHIIIII@9DDFGABFHIHIIIGGIGFB8BGGC@FF(55CCEHGHFFDFECC=AB5@CC3@CDDD?ABDCCBC@C
@57B
CAGGCTCTCCGAGGACGGGCTGCATAGGGAAGGGAAGCCCATCAACCTCTCTCATCGGGAAGACCTGGCTTACATGAACCACATCATGGTCTCTGTCTCCC
+
CCCFFFFFHHGHGJJJJJJIJJIIIIIIJIJJJIIJJIJJJJJJJJHHHHFFFFFFEDDDDDDDDDDDDDDDDDACCDDDDDBCCDCDC@CCDCDDDDDDD
@57C
TTTTTCATTTGCTGAAAAAAAACTTTGAAGTTAACTATCAAGAGTTACAAGAGGAGTATGCTTGCCTTCTCAAAGTAAAAGATGATTTAGAAGACAGTAA
+
@@@FDDDFFHHHHJJGIIGIGJJJIIIIIJGIGHJEDHGIIHIIIIIGGGCBDEHGEHIHIGHEACED@DDFFECCCCCEC;C:;@CDDDCDDDDDC:AD
@57D
CTCCGGGCAGAGCTGGATGAGATGTATGGGCAGCAGATAGTGCAAATGAAACAAGAATTAATAAGACAACACATGGCACAGATGGAGGAAATGAAAACACG
+
@;@BBD>DAAFFBBFGBFFDGCBB9?FF@DBFBD>?FGEF9BAD><DFE<CFIII@FFFFE>D@?).=?(?BD@AC@6;=?(;@A><<8??>>BB@@B885
@57E
CCATCATGCACCCTCTGATCCTGAACCCCCGGCACTCCGTGGATTTCAAACAGTCCAGGCTCTCCGAGGACGGGCTGCATAGGGAAGGGAAGCCCATCAAC
+
@@@DDFDFAHBHBHDEHIIIICEHHIGIIIIHHGECGIIBFGHIIHIIGDGDA=?CEC>BEECEEDD?BDBDDDDDD??CDDCBCB@BDB<<AAABDC>CA
@57F
CAGCAGATGACTGCAGTTCAGAGGTAAATGGTTGCCGTTTTGTAATGAGAACAGGAAAGCGTACAAATTTATTGAGGGAAGAAGCCTTTGGTGTTGCTGAT
+
73((23))2).)=>)<)..;<.4@.94.4)=28=.)--(.5.<)733)0))09:<>73=)'-;=(639);1)6)))89'(9;;>0(-3;=<3((,((5:(8
@57G
CTTCCCACCACAAGGCTTTAAGCAGGAGTACCACGACCCAGTGTATGAACACAACACCATGGTTGGCAGTGCGGCCAGCCAAAGCTTTCCCCCTCCTCTG
+
CCCFFFFFHHHHGJJJJJJJIIEHIIIJFHGIJJJJJJJIJHHGIIIJJIJJIJJJJJHHHHHFFFEEDACDDDDDDDDDDDDDDDDDDDDDDDDDDDDD
@57H
GTCGGCCAATTACCATGTTCATTCCTTCCGATGTTGACAACTATGATGACATCAGAACGGAACTGCCTCCTGAGAAGCTCAAACTGGAGTGGGCATATGGT
+
@@@FDDDFDFHBFHGHGGHHIGGFFHGIGBCGFHIIDHIGGI3BB?GFDGDHGH@BGCFHIJIGJFHEEEE@BDFFCCCEEED@CDC;5:<BB@CCACCCC
@57I
CTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTT
+
@CCFFFDFHGHGGIJJJHJJIDHIIEHGIIJJIJCIIGIIIJIIGGGGGGHHIJGIJIJIIHIJIJJHGFHFFFFACCEEEDDDCC@CDDDDBDDB@@C>C
@57J
GTTTGAAATGAATGGCAAAGCTCTCCTGCTGCTGACCAAAGAGGACTTTCGCTATCGATCTCCTCATTCAGGTGATGTGCTCTATGAACCCC
+
?:=BBDEEGD?<DFEHGGECBCCHGCGHDEEEIIBHFCGHI9BGAEH3BDEGDGADGGGIGDHIIIFFHEHG@D>7??BA@CCAACCD;?BB
@57K
GTCAATATTGATGACTTGATTAGAGACCAAGGATTTCGTGGTGATGGAGGATCAACCACAGGTTTGTATGCTACCCCCCCTGCCTCATTACCTGGCTCACT
+
?8=DBBD>CDCFDCF@D><ECDHHCHGIIBAGGGAB?E8DG0?**?DF?;698?@3.77=(6)).;=7)=A7A7;?9<?BBB2<4@>>(:>((((83((:>
@57L
CCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATT
+
@@@FFFFDHHHBDIIGIJEIIIJJJJGIGIJJJJJJJJGHJJGIIIHIJJHIIJJGIJJJJJJIJGIIGGHHFHDFFDFEEECEEDDDDDDDDDDDDDDDD
@57M
CAACACCATGGTTGGCAGTGCGGCCAGCCAAAGCTTTCCCCCTCCTCTGATGATTAAACAGGAACCCAGAGATTTTGCATATGACTCAGGTAGGCCTGCGC
+
CCCFFFFFHHHHHIJIJJHIIGGIIJIJIJJJJJJIJJJIJJJJJJIJJGIJJHHHHHFFFFFFEDDDDDDDDDDDDDECCDEEDCDDDDCCDDDDDDBDD
@57N
ACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTAT
+
:11A=B4?:CCD>BE2AEF??:CEDEEFEC8?8;99DDD3BB0BD*?DDDEEBBCCDEDICED@76AA3?;73??;@>AA(65>;>?>9==83;>>A:::A
@57O
ATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCC
+
@@@ADFFFGHHGHJJJGIIIGGGHIJJGHIGEIHIJJJJGIGGGIIIIIIJIJIGCHEGHICHGIHIFHHB?BCBDCCDEDDDDDDCDCCDDDCDBDCCD
@57P
GTCCCATACAGTAAGCATATGCTCATTGGAGTCATCAATAACACATAAATGAACACCTGAATCTGCTTTTGAAAAATCCAGGCATCCTACTCCACGCTCA
+
@@@ADEEDFFHHDEGHGHHHC<BHHIIHCE;CFGIGDFGHHCHIIIIIIIIII9DEHGHCGHCHIIGHGHICAEHHIHFHGHHFEFFDCCAECCCBBBCC
@57Q
TGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGG
+
@@@FDDBDACFHBHEHEGIIIJIF<DHGGGFHGHHGIE>FFEHEHGGDFBCCHIEEEEBFFC=CD;@CDDAC@>CCCC@DD>@C>:@CCCBCCDCDC73<<
@57R
CTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGC
+
?@@DDBD?FFDD<@BEHGD=GCHIE@+8?FG?FHGGIIGGHIGAFGCFGHHIFGII@G>==C@EHFHHFB;?BDDCC@CCECCCCB@B<<A>ACBCB?@A
@57S
TTTTTCACTTGCTGAAAAAAAGTTTGAAGATAACTATCAAGAGATACAAGAGGAGCATGCCTGCCTTCTCAAAGCAAAAGAGGATTTGGAAGACAGTAAA
+
58(8;7))28>))))):.((((2)<689)))::))091=)9)(.).)))).91(8((6)3).).=>:988..69)6=(6((((,((5((,:22(:;+6+3
@57T
TACAAACTGCATCAGGAGATATGCAAACATATCAGATCCGAACTACACCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATGACATCTCCTGTGACTCTC
+
CCCFFFFDDFHHHJIGIJIJJJIJIIIJJJIIJGIIIHGJIJJEHGGJJJGIIJJJJJJJJCHGIIIJIJHHFHHFFFCEEDEEDDEDCDDCDCDEDDDDD
@57U
TTGGAATTGTTCTGTATGAATTGATGACTGGACAGTTACCTTATTCAAACATCAACAACAGGGACCAGATAATTTTTATGGTGGGACGAGGATACCTGTCT
+
???;DDD+=DDADEDBE@EB:B<E,AFBFFIEBFE<E?CEDEEIIEBDEEDEEEE@DDDD9==7BCCDDCAADIDDAAD;=;@D@6;?;???9>>AAA>AA
@57V
CTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATG
+
@@@DDEDEHHHA?>GEEGGDHHG@FEBHEG9BG9??FDDGCH>@GHGE?AEACE>>;@:;AAACDDCCCCCBDDDB@@D8ABCCCCC<+<?<?AB<CCC:>
@57W
TTATTGCCTGGACTGGTCGAGGCATGGAATTTAAACTGATTGAGCCTGAAGAGGTGGCCCGACGTTGGGGCATTCAGAAAAACAGGCCAGCTATGAACTAT
+
CCCFFAEFHGDH?HGGHHEIIIGIJGIDIJJGIJI@BG@AEHG/?BFGBE=FBAFEEIJIHFFDDBBBDDB@DCCDDCDDDDDBCDDBABDDCCDDC>@>:
@57X
CCACAAGGCTTTAAGCAGGAGTACCACGACCCAGTGTATGAACACAACACCATGGTTGGCAGTGCGGCCAGCCAAAGCTTTCCCCCTCCTCTGATGATTA
+
CCCFFFFFHHHHHJJJJJJJJIIJJJJJJJJJJIGHFHIGIJIJJJJIJJIJJJJIJJHHHHFFFFDDDDDDDDDDDDDDDDDDDDDDDDDDDDEDEEEE
@57Y
GGAGACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTT
+
@<@FFFFFFFDHHJIIGIGIDGDGH@GHIIHGFHGHJFIHGGGIEHHHFFFDDBBDDDDEEDDDDDDCDDDDDDDDDDDDBDDDBDBBDD?BDDDEDDED
@57Z
CCAAGATATCCAAATGATAGTGTATATGCTAACTGGATGCTTTCACCCTCAGCGGCAAAATTAATGGACACGTTTGATAGTTAAGCGGCCGCTTAAAAA
+
8??DA:ADFBDFA4<CHC9IIGDBE@H::???FHCG3C<BEHI4?9?DFBFB@G:;@@@FD:==CGGE7769B@9?@A@C;>;A>CB=8;>BBBB@CC@
@580
AGGACCTAAAGGTGTATATCAAATCAGCAAACAAATCAAAGCTCATGATGGCAGTGTGTTCACACTTTGTCAGATGAGAAATGGGATGTTATTAACTGG
+
@@?BDDDFHHGG:ECFFGIIIGCGEEHFIIGBBFDGCFGHGEGFH@ADBGGCHGGGDF=FEHGHGDGGH@@EHHGIDEAHFHEFFEEA>C@CEADCDDD
@581
TGGAGACCTGAATAAGTTCCTCAGGGCCCATGGGCCAGATGCAATGATCCTTGTGGATGGACAGCCACGCCAGGCCAAGGGTGAGCTGGGGCTCTCCCAA
+
??7DBD=DHH;DFIIGIGEHFGIGGHGEAHGDD@BCAB:DEGGFHIGGEHIHI<FHH<FHBGIGFGHFEEEECCC@BBBBB,8?<>::?@3<9AACCCCC
@582
GGGAAAGCGAGAGGGAGACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGG
+
CCCFFFFFHFGFGIIGIJIJJIIJJIIIJIGGGGIGHIGIIEHHHEFFDAEEECDDDDDDDDDDDDDDDDDDEECDDDCDCDDDD@BDDDDDABDDDDDDD
@583
GGATTATAATCATGAGATTTTAGGACAGCAAATTAATGACTTTACCCTTCCTGATGTGAACCTTATTGGGGAGCATTCTGATGCAGCAGGGCTTGGAAGG
+
=:8+ADDD:?:?DAE?EEAEF4FD4<EFIIBDEC?C<CEDEIDAACDDD>@BDC@DE:?BD2=B@B<BCA/(-:;?D:7;;AA3>A(;2(355525>>A=
@584
CCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTTATGGG
+
CCCFFFFFHHHHHJJJJJJHIJJJJJJJJJJJJJIJJJJJJJIJJJJJJJJJJJJJJJIIJHHHHHHFFDDDDDDDDDDDDDCDDDDEDDD39<BDDDDDD
@585
CTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAAC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJIJJIJJJJJJJJJJJIJJJJJIJJJJJJIJHHHHFFFFFEEEEDDDDDDBDDDDDDDDDDD
@586
CCTGTCTCCAGATCTCAGTAAGGTACGGAGTAACTGTCCAAAAGCCATGAAGAGATTAATGGCAGAGTGCCTCAAAAAGAAAAGAGATGAGAGACCACTCT
+
@@@?DDBDHADHHIDIEGIIIHHAEBF6;?GDGEDGCDFDGHGCGAHGGHIEHDGDEFH@=B@@C=C=DGIHEHEEEBDEECCE=CCACCA@:?CBC9:?@
@587
GGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGCGTTT
+
??<A13?B?A2ADEIE7AC3CEE+A9F4<?:?D@EECB;D39?BBD>D9B*9@'@A;;6@3?77?CD77)7<'331=>9?<<8;??>>4>AAA<<(0;&5
@588
GTTCACTCCGCTATTCCTATGCGAAAGGAACTATGTAAAACGTGGCTGGACAGTGATATATGTACAAGGTTTAGTTCTATCCAGTATCCCTTTACTCCATT
+
-(022))))--((<)):.);))2=(</(=1().07..)<))(96(7=(-=(<3))<)<)).))).))8(.;.)(6(.((6.990(-(:7;0;;((7,3(,(
@589
ATTAAACACAAAAATAATAGAAGAAGAAAAGAAAACTCTTGAGCTAAAGGATAAATTAACAACTGCTGATAAATTACTAGGAGAATTACAAGAACAGATTG
+
@??DDDDDBFBFFGIGEHIEIIIGEHEHGE@BEHHGIFGIIGGIDEGGIIDHIEHDHDHGBAHIGICGCACGAEHGGH>EBD;BEECCACC@CCCCCCC@C
@58A
GCAACGGCCTTCCATCTGAAAGGCAGAGCAGGGGACACCACGGCGGCCGTGAAGATGCTGAAAGAGAACGCCTCCCCGAGTGAGCTGCGAGACCTGCTGTC
+
???+:)=DDDADDEAEEEIEE>+??;)1?*??D))6/B1=BBA'4=??=,&8=A(3:A:>3:A>>>99A>?510<<>9?>+8>AA(3>&0&5&8(9<AA:A
@58B
AGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACC
+
@@@FFFFFGGGAHIGIIIFGHIIIGHIDHIIIGGEHIHIJJJJJJJBGGIJJGHHFFFFFECCEEDEDDDDBDDDDBDD@BDDDDDDDBCDDDDEDDCDDD
@58C
GGACGTCCTATGTACCAACGCCAGATGTCTGAGCCAAACATCCCCTTCCCACCACAAGGCTTTAAGCAGGAGTACCACGACCCAGTGTATGAACACAACAC
+
@@;DDDDFFFHHHIIIIIIIGAFHGGIFDFFCFHHIIIIIIIIGHIIIGGIGGIIGIIIGHHEFFFFEDB=A@CCCCCBB@BCC?(++::3>CAC?BBBBB
@58D
GAAGGAATGAGGGTTACCTATGGGACTGAAGGACTGCAGCAGTTACAAGAATTTGAAGCTGCCATTAAACAAAGAGATGGCATTATAACCCAGCTCACTGC
+
@@@FFFDDDHHGBAGHHIJJEIJGJJJIEEIIJJGGHIJIIJJIIJGGGHIJIHIJJIJIGIIIIIJJGIIHHCED@>CDEEEEEADEDDDBDDCDDDCAC
@58E
CTGGAACTGATGGAGGGAGGAGACCTTCTTACTTATTTGCGTAAAGCCCGGATGGCAACGTTTTATGGTCCTTTACTCACCTTGGTTGACCTTGTAGACCT
+
@@@DDDBEHCFFHIIGJFHBHGDGIGGGIGIIGIGIJIGGE@DHAGHIGIIAABEFEFFF?CEDCDDDCCCDDDDDDDDDDDCACCDB?C@CACCCDEDCD
@58F
CAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGC
+
@@@FFFFFHGHHGGGGIIIGGDDGDCHIIIIJIEIIII@FHDHIGHHGIHEEFHHHHHCBEFFFDBDCCDCCCCC@CDDDCDDDDDDBB?DDDBBCDDDC
@58G
CGACGTTGGGGCATTCAGAAAAACAGGCCAGCTATGAACTATGATAAACTTAGCCGTTCACTCCGCTATTACTATGAGAAAGGAATTATGCAAAAGGTGGC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJIJJJJJJJJIJJIJJJJJJJJIJJJIJIJJHHHHFFDDEEEEEFDDDDDDDDDDDDDEDDEDDDDD>CDD
@58H
GCCGGGGACACGAGCCCGGGTGGTTCCGCAGCGGGGGCAGAACTAGCAGGTAGTCGGAATTCTCCAAGAGAGAACGAGGGAGACGGAAGTGGAGCGGGGGG
+
-(0((-((0(2838((((((0(-'(/)'-5=-',3'&))0((+((+(+((+(((+0&&8(5(:2:+2(((++(((&*&))0&&((&&()+(+(((&&)0&0
@58I
CTCAAATAAAGAAGAAATACAGGAAAAGGAGACAATCATTGAAGAATTAAACACAAAAATAATAGAAGAAGAAAAGAAAACTCTTGAGCTAAAGGATAAAT
+
@@<DDDDFDFDHHIIJGIIJIGGHGIIJJGGGIIJJJJIJFIGGIIJJJIJJIIJIJJJJJJJIGHJIJIIEHEHFFFFFDDEEDDCDCDDDCDDDDCCCD
@58J
GTTGCTCTGCTGTCTTGTGTTTTTGCAGCCTCTACAACCCCACGTCAGAGTGTGGGATTCTGTTACTCTATCCACACTGCAGATTATTGGACTTGGCACCT
+
C@CFFFFFGHHHHIIJJGGCGIJJJJJJJJJJJJJJJJIJJIJGHIIJIJCFGGIIIJJIJIIHHHGGHFFFFEDCCEEDDDDDDDDFDCDDDDDDDDDDD
@58K
CGACGAGATTGAAATCGACTTTGAGACCCTGAAGCCGTCCACACTGCGTGAGCTGGAGCGCTATGTCACCTCCTGTTTGCGGAAGAAAAGGAAACCTCA
+
CC@FFDDD=?FDHIIIIGIDGIGGIIIIGIIICGIIIDHHIIIIIIGIAHGEHFHHDEDCDCBBCDDDDDDDDDDDDDDA>B<>B?CCDDDBCDDBDDD
@58L
CCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTAT
+
@@<DFFBBBFFFDGGGGGHGGGGIJG@GGIIIIGBF@GHGAEHGIAGHIIJHHFFFFFFCCECCDCCDDCDDDDDDDDDBDB?C@C@CB?CBBDDDDDCD>
@58M
CGGATGTAATCAACACCGCTTTGCCGATAGAATATGGTCCACTTGTGGAAGAGGAAGAGAAAGTGCCTGTGAGGCCCAAGGACCCTGAGGGGGTTCCTCCT
+
?8?DBDBD?DDBBBFGFG>ADE<FHG6FB@*:?GBHEFA?B@DFG=C;)@>=@F(.(62=A?A@;;;;;;@>>>=(;?AA??BAB<C(9??BB<BB:>>>3
@58N
CCCACGTCAGAGTGTGGGATTCTGTTACTCTATCCACACTGCAGATTATTGGACTTGGCACTTTTGAGCGTGGAGTAGGATGCCTGGATTTTTCAAAAGC
+
@@CFFFDFHHBHCFEFGGFHHJJJJIJIJJJJJIIJJGIIIJGH@FHIIJJIGIGIJIGGIJJJJJEIGE5@D=?>ACECCCBDCDDACCCDDCDDDDCB
@58O
CGGAGGAAGAGGACAAGTGCAAGCCTATGTCCTATGAGGAGAAGCGGCAGCTCAGCTTGGACATCAACAAGCTCCCCGGCGAGAAGCTGGGCCGCGTGGTG
+
@@@BBDBABAFA;ACFE2AHECCF;FCGDIIFFDFGBCEE==@0?DFF@-;7=CEBC:BBD;BCC@CCC?3=5>A??BB5@<BBB?AB@BB?@5@30<5<?
@58P
GGATGCCTCCTCCTTGCCTGAAGCCAGTCAAGAGGCAGGGAGCAGAGGCAATTCCTTTTCTCCTCTGTTGGAAACCATAGAACCTGTCAACATACTAGATG
+
CCCFFFFFHHHHGIJJJJJJJJJIJJJIJIJIIJJIIJJJGIJGHIJJJIJJJIIJJJJJIJHHHHGBCDFFFEDEDEDDDDDDDDCDDEDDDDDDDDDCD
@58Q
CTGGGCCATACAGACTGTGTGAAATGCCTTGCTATACATCCTGACAAAATTAGGATTGCAACTGGACAGATAGCTGGCGTGGATAAAGATGGAAGGCCTCT
+
@;8D1D;;CDBAD@FBF2AFGI>:<+22<9CB<9??E<<?F@?*B39)89?G>?FGC;B8..)B=.==D=E).77=>-,99>5--55>(--:>@355559A
@58R
GGATTTTAGTCTATATGCTTGTGCTTCTCCAAAAACACCCATCCAGGCAGGGGGATATGGAGAATTTGCAGCCTTCAAGTAGCCACCATCATGGCAGCATC
+
@CCFFFFFHFHHHJJJJIJJJIJJJJJJJJJJJJJIJJJJJJJJJJJIIJJJJJGHHHHHHEFFFFEEEEEEDDDDDDDACDDDDDDDDDDDDDDDDDDDD
@58S
CAGAAGTGCCTAGCTGCCACTCCATTTATATGAGGCAAGAAGGCTTCCTGGCTCATCCCAGCAGAACAGAAGGCTGTATGTTTGAAAAGGGCCCCAGGC
+
=??DB:A=DBDDB+:C;ADED;AEEDECFAAECEEC)?@??;@DDDI9BABD>?BDA>C>)2@DAAD@D;?=;(=66?AA7;;AAAA>3=7>=??=78(
@58T
GTCCCATCAGTTTGAACAGTTGTCTGGATCCATTTTGTGGATGGCACCAGAAGTCATCAGAATGCAAGATAAAAATCCATACAGCTTTCAGTCAGATGTAT
+
?==1AD:DA?CFD>GD<E:AI:3CHH@FHGEHCB<FF?CFG*9?DFFE9?)9??DFGBECBF<B:C@CCDEECEFEEEC>ADD>:BDC@@;>AA>;@B>AB
@58U
GCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACC
+
8?@DDDDDHHFHDHC>GGGC>D>:C?EHIICCC9CEFIAADGHID:DBDHGGF@@CBFFEGHE3@CHEHHH?C7@DEDCA>;>=;@C@C>CBB3<?CCCB
@58V
CTACACCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATGACATCTCCTGTGACTCTCACCTCTCAGACAACTAAGACAGATGACCCCCAATTGAAA
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJIJJGHIJJGIJJJJJJJIJJJJJJIJIJIIJJJJJJJJJJJHHGGHFFFFFFDEEDDDDDDDCDD
@58W
TACAAACTCAACTCATACACCGAAACCTGACCGGGCCTTCCCAGCTAACCTCCCTCCATCAAAAAACATACCAAAAAAAAGCTACCCCCTCGACCACCCTT
+
(((2=4@<<46)6:<=>>?5)3=>==(6(3)1(-(5(-.)..;)(.)80.6633:>(8.:((.(.''5(,((7(7(7&)))6(+3565&&&&&&0&+()(+
@58X
CTCTACAACCCCACGTCAGAGTGTGGGATTCTGTTACTCTATCCACACTGCAGATTATTGGACTTGGCACTTTTGAGCGTGGAGTAGGATGCCTGGATTTT
+
@?<DBBA;:C?@CG:A:AE><2A*1))):;D9BB?B*0?**0999*97083=CF3))).=@=7).=DEAA=C>7)5;(3'38(5,:::,:A,::>BB:@>4
@58Y
CAGGAACCCAGAGATTTTGCATATGACTCAGAAGTGCCTAGCTGCCACTCCATTTATATGAGGCAAGAAGGCTTCCTGGCTCATCCCAGCAGAACAGAAGG
+
CCCFFFFFHHHFHIGHIJEEFHHEGIHIGHIGGGEGGDFDGGIEIIGGHGIHIIIGIIIIHHEGGIIIGEGHEHHHGFFECDEEEEDDDBCDDDCCCCCAB
@58Z
AAACAGGCCAGCTATGAACTATGATAAACTTAGCCGTTCACTCCGCTATTACTATGAGAAAGGAATTATGCAAAAGGTGGCTGGAGAGAGATATGTCTAC
+
CCCFFFFFGHHHHJJIIJJJJJJJJJJJJJJJIJJJJJJJIJJJJJJJJJIIJJIIGJJJJJJJJJJHHHHHHHFFF;@CBEDDBDCD??@CDDADDEED
@590
ATCTGACTCCCTGATTTATGACGACGGCCTCTCAGAGGAGGAGACAACGCTGGTGGACTGTAATAATGCCCCCCTCCCTCGAGCCCTCCCTTCCACATGG
+
?@;BDDDDDC?DF;EFHEICEIGIEFGHA@D99BDHEBGGBG?@CG).;BEEE?BB=AC?>CDED@ACCC5,300<<<?C9-9>>?9<B<<CCC>@@>>?
@591
CAATACTGGACCTCCCCCACGGGGGGAATCTACCCCAACCCCAACGTCCCCCGCCATCCTAACACCCACGTGCCTTCACACTTAGGCAGCTACTACTAGA
+
@<?DAADD?FHBFHG@E:CGBAB<:369A8ACCC??<<?@BB8?@788?9AB-<B2??ACC@B3>B;8?@??A<ACCA>:+3@3>A448@93@:>CAC<:
@592
TGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCC
+
???D=D:3A=CADEF<CE?BF@GA9F@D9FEFF<??B9?@>FFE3?FGADF67B=F8=>;;=CC=@>=CECEDDDDD:;AAB8;;@B>@83@4>>8<@BB
@593
GAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTC
+
BBCFFDFFFHHFHIJJJIJGIIIGIJIIIJJJJJJIJJJJJJJJJJJJJIIIGHHHHFFFFFCCBDDDBDDDDDDDDDCCDEDDDDDDDDDDDDDDDDBDD
@594
GCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACT
+
CCCFFFFFHHHGHJJJI?FFIJJJJIJJCFHIJJJJJJIJJIJIIJJJJJJJJGIJJJJIJJGIJGHHFFFFEDEEEEDEDDDDDDDDDDDDDDCEDDDDC
@595
CTTCAGAAGAGAAATCATAAAGACAGCCAGTTCGAAACTGATATAGTACAACGAATGGAACAAGAAACACAAAGAAAGTTAGAACAACTCCGGGCAGAGCT
+
@@<DDD;??DDDAAFHGBCHAB?DBGIDFEHGGFII?FAFIDGCGGHGGII>FGGCGFHGEF>==GHGHEC;?;7?BC;6;;;A>?C9A@@B@BBB>BB?>
@596
CTATGATAAACTTAGCCGTTCACTCCGCTATTACTATGAGAAAGGAATTATGCAAAAGGTGGCTGGAGAGAGATATGTCTACAAGTTTGTGTGTGATCC
+
@@@DBDFFHHGFFHEIJJHGGIIGHIGIJGIIIJIIGGGGJJJGIIGJIIIIJJJJIGI8CHGIIGEEHEFFFFDEE@DECDCDCACDCAC9?9<@CAC
@597
GAGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTATTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCAC
+
711+++2?=8=<?<2<4+2=A?4?AA4<*:**)000=)87A2//0)9>=7>>)=.8>>)7))75A:<@(,;;>999((5((((3(++(8:35;&9;?;1+8
@598
TTCATCCTCAGAAGACAGGAATCGAATGAAAACACTTGGTAGACGGGACTCGAGTGATGATTGGGAGATTCCTGATGGGCAGATTACAGTGGGACAAAGA
+
@<@DDDDDBBABFGGGIIGF@FHGB;BHGIIGHIIGGHGBA?FCGGIIDFHEHG=C@DHDG;CAEC;9>BE@@A;A@CCBCB;;@CCCC5@C@952<CC9
@599
CAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATAT
+
CCCFFFFFHHHHHJJJJJJIJJJJJHJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJHHHHFFFFFFEEEDEDDDDDDDCDDDDDACEDEED
@59A
GAAAACTCTTGAGCTAAAGGATAAATTAACAACTGCTGATAAATTACTAGGAGAATTACAAGAACAGATTGTGCAAAAGAACCAAGAAATAAAAAACATG
+
@CCFFFFFHHHHHJJJJGJJJJJIJJJJJJJJJJJJJJJIIJIJJIIJJIIJIJIJJJJIJGIIIGIGGIIEHIIJJHHHHFFFFFEEEEEDDDDDDDDC
@59B
CTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCT
+
@@@FFFDFGFHFFGGIJIJJIJIGGGHIIJJIJJIJJGHFIGIJJIJJIIEGGI>CDEGGFHFBCCDECCDCBDBDB@DBDDDACCCCCCDDCDDC@ACCC
@59C
TACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTT
+
@@@DD?DD?FFAFFII<CIIFIIIBEGGIIIIIIIIIIIIIFEGIEAFFIIIAFFIIIIIIGIIIEFFFFFDDDDCCCCEECBBBBBBB?BBB;?<>BBE
@59D
TGAAAATGTTGAATGTGACAGCACCTACACCTCAGCAGTTACAAGCCTTCAAAAATGAAGTAGGAGTACTCAGGAAAACACGACATGTGAATATCCTACTC
+
CCCFFFFFFHHHHJJHIJJJJJJJJJJJJJJJJIJJJIHJJJJJIIJJJJJJJJJJJJJJGIJIIIFHIIJJJIJHHGGFFFDDDDDACDEEEEEEEDDDD
@59E
GGGGACAGTCGAAGAACTTCAGAAGAGAAATCATAAAGACAGCCAGTTCGAAACTGATATAGTACAACGAATGGAACAAGAAACACAAAGAAAGTTAGAAC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJGJJJJJJJJJJJJIJJJJJJHIJJJJJJJJJJJIIIIJJJJHHHFFFFFEDEEEDDDDDDDDDCDDDDCCDCDDD
@59F
ATGGCACAGATGGAGGAAATGAAAACACGGCATAAGGGAGAAATGGAGAATGCTTTAAGGTCATATTCAAATATTACAGTTAATGAAGATCAGATAAAGTT
+
?@@ADD:DHFAFFAE?F?FHDCD>CFG;@D<D@FGHEIDG@D?BBFI=C=@CGAFHIGGG;CCAAEHCA;@;>BDE;@ACCC>A;5;AC;ACCCCCCC>;:
@59G
CTTATTCAAACATCAACAACAGGGACCAGATAATTTTTATGGTGGGACGAGGATACCTGTCTCCAGATCTCAGTAAGGTACGGAGTAACTGTCCAAAAGCC
+
CCCFFFFFHHHHHJJJJJJJIJJJJJJJJJJJJJJJJJJIJJDHIIJJIJIJIHHJJHFHHHHFFFFFFEEEEEEECD@CDDDBD@DCDEDDCDDDDDCDD
@59H
ATCAGCGTCCACTGCTGAAGACAGACATGGAACGTCACATCAACGAGGAGGACACAGTGCCTCTTTCTCACTTTGATGAGAGCATGGCCTACATGCCGGA
+
CC@FFFFDHHHBFHIJIIJJIJJJJIJJJII@GGHHGIIJEGIIHIJJIJIIIGGIEEFGHEDFFFFFEACCEEECDDDCCDBCCDDDDCDCCCCCC>BD
@59I
AGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGG
+
@@@DFFFFGGGHDGHIIGHGHIGHGIEGJJGJJJAGHIJIJGIEGIGEEGEGHIJHHIGIJEFGHHIJIGGDFFDFEFECCEEDDDDCCDC=B;@BBCD?
@59J
GGATCACTTCAGCTCTGGCAGTTTTTGGTAGCTCTTCTGGATGACCCTTCAAATTCTCATTTTATTGCCTGGACTGGTCGAGGCATGGAATTTAAACTGAT
+
@@@FDFFFGHHHHIJJIJIJJHIJJJJJGIJJJJJJIJJJIJGIIJJJJJJIJJJIJJIJJIJJIIJEGIIJGGDHHAEDDCDDDDDDDDDDDDEDDDDDD
@59K
GAAAAACTTAAAGATAATTTAGGCATTCACTATAAACAGCAGATAGATGGTTTACAGAATGAAATGAGTCAAAAGATAGAAACCATGCAGTTTGAAAAGG
+
??@DDDDDBADFBIEFEF@@<AEG<C@@FF>B<EEFEFEGAAE?F999:D0?DDGGEEEDFGII@FGA@FGGFD=C=C=?AEEEDBD>;;;@ACA>>;>B
@59L
TACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTT
+
@@@?BB?B??FFD;FGC:CBBCFFGE8DGFFEDEB@;?GEEBBG@GFEEDFFICFF9=8=FAE@=)??E>ABBDB;;;AA@ABABBBB;5??;620594>
@59M
GATGGGGACCCCCTCATCATGGTCTTTGAATACATGAAGCATGGAGACCTGACTAAGTTCCTCAGGGCCCATGGGCCAGATGCAATGATCCTTGTGGATGG
+
:11+2+++<7=C<7=<7CC9C3A<:@=ABA<::::AB<7*?=A;*0*<ABBB78).=78).777))(--9;7.76>;;=?95;;5(,;??=959=5;(8;0
@59N
CTGGAGACTCAGGTGGAGTCATGCTTATATGAAGCAAAACTACTGTAGAGCCCACACCTGGGAAAGGACCTAAAGGGGTATATCAAATCAGCAAACAAATC
+
?<?=D+A222ACBEA7+A+3?4A>+++++2A*1?3*:?CD<9??>9B<9*?;D;(7;B;C95;;((=(6?37??;A(938AD(;(5(-->,(5<A????4:
@59O
CCAGCAATCAGGTGGTCGTACAAACTGCATCAGGAGATATGCAAACATATCAGATCCGAACTACACCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATG
+
CCCFFFFDGHHHCGIJIEGGGGIHGJIEHGHIJGHHGGJGHIIJJJIICDBGGIGGGJJJIIGGHHHHHFFFFEDCDEECCECDDCDDDD?C@@@C98A:3
@59P
CTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACC
+
@@@DDDEFHHHBBH?HHIID@AFHGACE?FHEGGIIIIIIIIIIIGIIA;FCHGIII@EEHH?D;;>CCDEEDD38ACCAAC?CB:<>CCCCCCD@CCCC<
@59Q
GTTTTATGATGACACCTGTGTTGTCCCAGAAAAATTCGATGGAGACATCAAACAAGAGCCAGGAATGTATCGGGAAGGACCCACATACCAACGGCGAGGAT
+
@@7DDABDDFB?FG@EEIGIHBEGHHIGGIIEIH<FHGDGIGG;DGHIIIII@HGDEBCGHGGGICG;C=AEEEDCCBB@B@B?B:C:<@C7?B5<B<@<9
@59R
CCGGAAGTTCACTACAGAGAGTGATGTATGGAGCTTCGGGGTGATCCTCTGGGAGATCTTCACCTATGGAAAGCAGCCATGGTTCCAACTCTCAAACACGG
+
@@@DD@DFDHGFFIIIGCHIICEGHCFDHE@?CBHIIIIIBH?CFDBDGHGGGGE@DGHFHFFGC@CCCBCA@CEDDBD>>?>CCADDACCCCCDCC?BDD
@59S
GCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJIJJJJJJJJJJJJHGJJJJJJJIIJJJHHHHFFFFFEEEEEDDDDD>CCDEDDCDEDDEDDDDDDD>CDDDDDD
@59T
CACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACC
+
CCCFFFFFHHHHHJJJJJIJJJJJJEIIBHIGHGIIJGIJGGJJEFHIJGIJJGIJIJGFEGGIC@EEEHEFCEDDDDDD???BACDEDDCFC<@BDDD?B
@59U
ACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCT
+
CCCFFFFFHGHHGJJJJJJJJJJJJJJJHIJJIJIJJJJJJJJJIJJJFHJFIJJJGIJJJJIJIJHHHHHFFFFFEEEEDEDDDDDDDDDDDDDDDDDDD
@59V
AACTAAGACAGATGACCCCCAATTGAAAAGAGAAATAAGGTTAATGAAAAACAGAGAAGCTGCTCGAGAATGTCGCAGAAAGAAGAAAGAATATGTGAAAT
+
CCCFFFFFHHHHHJJJJIJJJJJJJIJJIJGHHIJJJJJJGHJJJJJJJJJJJJJJJJJJJJJJJJGHHFFFEFDDDDDDDDDDDDDCDDDDDEEDEDDDC
@59W
CAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCC
+
@@@FFFFFHHHHGJJJJHIHJIGIIJJJJIJJIJJJJJJJIIJIJJJJJJJIIGIGIGHHEHEFFFFFFEECEEEDDDCCDDDDDDDDDDCDDDCDDDDDD
@59X
GGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATC
+
@@@DD?AD?FFHHGGGIIIIIGIIGEADHHIJJDHEG>BFHGGIGEGGIIGIJJIGIG7CHHGHGFDDDDEEEDDBCDCDCDDD<5:@ACDDDDDC?BCCC
@59Y
CCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTC
+
CCCFFFFFHHHHHGIIFHHGJJGIJJJDGHGIIJGIHIGIJIIGIIJJIIGGIIIEGIGIJJIJJHGHFFDFDEDEEEEDD?CDDCDDDDDDDDEDDCDDD
@59Z
CTGGATGACCCTTCAAATTCTCATTTTATTGCCTGGACTGGTCGAGGCATGGAATTTAAACTGATTGAGCCTGAAGAGGTGGCCCGACGTTGGGGCATTC
+
@@???BDDDDDHFGBHII@FBDHGIIIIICADHHEGHGGE=CG>HIIFCGHIIICEEEGGIE77CHGFHHH@@E;7;>A..;;;=@8/9<<ABBBBB?CC
@5A0
AGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGC
+
@CCFFFFFHHHAHIGHIIIGEHIIIHGGIGHEHGHGIIDHEGHIIIIIIII@=FHGHIGIIGIIIIIIEFEFDEEECEDDEDDDCCDCDCCDDDDDDDDD
@5A1
GGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCC
+
@@@FB1BDHHHHHIGGDIHIFCHHG;??CFHGH@FIGIDIIIIDDEGGGG@EAA=?ECDBBDDCC@CA>>?CCDDCDCCACAACCBDDD9B@CC@CBBA??
@5A2
GTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCC
+
@<@DDDFFGHFFFGGEIGEEGGHGGGGIII9DDFE?F@FEEHE68CCGF>CCCEF:B>BCDEC@CCCCCCBBBB7ABBB?<ACCD3>>>>A4@@CBDBD
@5A3
GGAAAATGAGGACCTCAAACAACAATGTATTCAGCTAAATGAAGAGATTGAAAAGCAAAGGAACACTTTTTCATTTGCTGAAAAAAACTTTGAAGTTAACT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJIJJJIJJIJJJJJJJJIIJJJJJJJJJJIJHHHHHHHFFFFFDDDDDDDDDDCDDEDC
@5A4
CCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCC
+
CCCFFFFFGHHHHJJJJJJJJJJIJIJJIJJJJJGIJJJJJJJGIIJJJJJDHIIJJJJJJJHHGFFBEFEEDDDDDDDDEEDDDDDDDDDDDDCDDDCDD
@5A5
GCAGGAGTACCACGACCCAGTGTATGAACACAACACCATGGTTGGCAGTGCGGCCAGCCAAAGCTTTCCCCCTCCTCTGATGATTAAACAGGAACCCAG
+
CCCFFFFFHHHHHJJJJJJJIJIIJJJJJJJJJJJJJJJJJHIIJJJJHGJJJHHFFFDEEEDDDDDDDDDDBDDCDDD@CCDEEEDDDDDDBDDDDDB
@5A6
TCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAA
+
CC@DDAEDFFHDFIIJJHJJJIGIIIJJCADFCBFGGIAHHEIIJJGJBHIDHGFHGGHIIGHGF<DEC>>>CCCDC?<ABDB>C@C>@;ACDDCCCDB
@5A7
GCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACC
+
@@@DBDFFHHDDHBGIJGIIHJIGCDDEIIGIIGHJJIJJIJFCB?DHIJIIBDHIIGGHG=GIJJIIHBHHF@BCEF@CEEED=CCDDD>AA:?BCDDD
@5A8
CCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCC
+
CCCDFD>;DHDHHEHBFFEIBGGGECCCEGG<F@?DFGEHIIIDFCDHGHGBGHDGIGIGEHEHBDF>@D<CCB?;5>CCDCCDD:@BDDB<AD@CCC>AC
@5A9
CAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGAC
+
CCCFFFFFHHHHHJJJJJJIJIJJJJJJJJJJJJJJJJJIJGIJJJJJIJJJJJJJIJIJIJJJHHHHHHHFEFEEEEEEDDDCCDDDDDDDACDDDCDBD
@5AA
CAAAAGGTGGCTGGAGAGAGATATGTCTACAAGTTTGTGTGTGATCCAGAAGCCCTTTTCTCCATGGCCTTTCCAGATAATCAGCGTCCACTGCTGAAGAC
+
:==1=@A2???A<C@=;+31+<2>A11:@B<A<:7:<:7::?;AB0*?AAB9>>BB;AB9ABB>B=A6=AAAA9A@@>;7?>>@@=;;==?9;;????(9?
@5AB
CCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTAT
+
@@CFFFDDHFHBFGEHIJJEHGIJJJJJJJGIJIFHIGGJIJJIGFIIJJJFFHFEFFFEEDCCACCDDCDDDBCBBDBBBDDCDDEDD<C@B@DDCDCCD
@5AC
AGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGG
+
CCCFFFFFHHHHHJJJJJJJJIIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHHFFDDDDDDDDDDDDDDDDDDDDDDDDEDDD
@5AD
CTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTAT
+
@@@DD?DD;FHHFHII?FEGBFFHEHGHIGGHIHDGEIIIIAFCG=C7@DHH==?A?D>>DEE@C;A?@BACCCCCC:;ACCCCBB?BBBB?8<@>?@CCC
@5AE
TGGTGAGATTAGTTTTCTAAATGAAGAAGTTAAATCTTTAAAGCAAGAGAAAGAACAAGTTTCATTGAGATGTAGAGAGCTAGAAATCATTATTAACCAC
+
@@CBDFFEHHHHHHIGJGJJDIIJJIIJJHHHHIJJIJJJJJJJJJJIJIJIGHJGIJJGIJJJJJJCHIIJACGHGGIHHFFHHFFFFFFFDDEFEEED
@5AF
CTCCTGAGAAGCTCAAACTGGAGTGGGCATATGGTTATCGAGGAAAGGACTGTAGAGCTAATGTTTACCTTCTTCCGACCGGGGAAATAGTTTATTTCATT
+
CCCFFFFFHHDFHIGBHIIDIHGEGIIIIIIJGICGHCGHHIIGHIIGEDCC=C=CFGGIIIIEGHGHGHEHDHHDD<BCDBBDDDDCD:@DDEDDEDDDE
@5AG
AGACAACAAATGAAGTTGTTTTGGCTGTGGAGTTTCACCCAACAGATGCAAATACCATAATTACATGCGGTAAATCTCATATTTTCTTCTGGACCTGGAGC
+
@@@DFFFFHGHHHGHHHIGHHJJJEHHEGGGIFFHIGJJJDGEFGBBGEGHHEHII@EHIJJJJJGH>EH:<BEF@AECECBEDEDDCCCDDAACCDDBBC
@5AH
CCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTAT
+
CCCFFFFFHHGHHJJJJJJJIJJJJJJJJJJJIIGGJJJJJJJJIJJJJJJHHHFFFFFEEEEEDDCEDDDDDDDDDDDDDDDDDDEDDDDDDDDDDDDDD
@5AI
GTGGATAATGTGCACCATAACCCTCCCACCATTGAACTGTTGCACCGCTCCAGGTCACCTATCACGACAAATCACCGGCCTTCTCCTGACCCCGAGCAGCG
+
C@@FFFFFHHHHFIIJJJJJJIEHJJJJJJJJIJJJIJJIIIIIJIJFEHIIIIHGJJIIJJJJJHGFFDEEEEDDDDDDDDCCDDDCCDDDDDBDD@CB9
@5AJ
AATTACCATGTTCATTCCTTCCGATGTTGACAACTATGATGACATCAGAACGGAACTGCCTCCTGAGAAGCTCAAACTGGAGTGGGCATATGGTTATCG
+
@@@DDDDDFHHHHHIEECEAFA@@FHFHGBEBFDEFHEHBGEDBGBFDDGIGHCEHIEGHAFGEHGGGDGHHHCAB>@@>@@.;AB@CC>CCC>CACC@
@5AK
GATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGC
+
@@@FFFDDHHHHHIGJJGIJIDFHCHGGHGIIIIJE=AHIHIIGFGHIIGIJJJBHHHFFFFA?CEDDCDCDDDDDCCCC9??A?BDD@BD@B>CCCDDD
@5AL
CAGGCTTTTCCATCCTGGTGACTCTGCTCCTCGCTGGCCAGGCCACCACCGCCTACTTCCTGTACCAGCAGCAGGGCCGGCTGGACAAACTGACAGTCACC
+
CCCFFFFFHHHHGJJIIIHIJJJIIIJEHIIJJJJIIIIJGIIJGHIJIIGJJJIIDHHGHEDFFFFDDEDEDDDDDDDDD@BDBDCBCDDDDDDDDDDDD
@5AM
CCAGTTTGGATGCTGGACTTGCAGAGCTGGCTCCTCTGCAAGGACAAGGGTTAGAAAAGCAAGTCCTGGGATTGCAGAAAGGACAACAAACAGGGGGTCGT
+
@CCFDDFFHHHHHGIIGIIGIJIIJJJIIGHIJJIJGIIIJJJIJIJIIJ?FHIJJJIHIIIIEEEGHHHEEBCEFFDCCCCBDDDDDDDDDCDDDB59B>
@5AN
CTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACC
+
CC@FFFFFHHHHHIIJIJJIJIJJJGJIJJJJJJJJJJJIJJIJGIJJJJJJJJIIGHHBEFDCCDEEDD>ACCDCDDCDEDDDDDBDDDDDDDDDEDDCD
@5AO
CCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJIJJJJJJJIJJJJJJJJHHHFFFFFFEEEEEEDDDDDDDDDDDDDDDCDDDCDDD
@5AP
CAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATAT
+
CCCFFFFFHHDHHJJJJFIIJJJJJIIJJIGIJJJJJJJJJJIJJJIIJJJJJJJJJJIJJJJJHHHHFFFFFFEEEECDDDDDDDDDDDDDCCEDEEA
@5AQ
AGGACACCTGCCCACTGAATGTTCATTCTTATGACCCCCAAGGAGAAGGCAGGGTGGATCCTGATCTGTCCAAGCCTAAAAACCTTGCTCCTTTACAAG
+
???DDEFFDDHFHIJIJFI4CEFGIIJJIJJJJGGGHIFGJDGGHGCGCGCHII85;=EHEHHEFFFFFDC@CECDDDDDDDDDDDDDDDDDDA>@CDD
@5AR
CCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAG
+
@C@DDFFFHHHGFGEIEIIIJJGIJJGIEGGIGIJHGGIIICHIIGIEEGHGGIIJGIGIGGHGGIIIFCCCCDFFFDDED>BB:CBCCCCCCCCD?C?
@5AS
TGGCTTACATGAACCACATCATGGTCTCTGTCTCCCCGCCTGAAGAGCACGCCATGCCCATTGGGAGAATAGCAGACTGTAGACTGCTTTGGGATTACGTC
+
CCCFFFFFHHHHHJJJJJJJJJJJHIIIJIJJJJJJJJJJJJIJJIIJJJIJJJJJJJJIHHHHHFFFEEEEEEDDDCDCDDDDDCDDDDDDDDDDDDDAB
@5AT
GCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTTATGGGCAGG
+
?;=DB3B;C82<CACAEBEECEFDEEDEE91?1:C?D?C4BADD?<:7.(==C=A7@ADEID':4?;;??=???=<5::>>>>9=(0)29>>AA?89;>
@5AU
CTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJHIJJJJJJJGHIJIJJJIIIJGJJJJJJJHHHFFFFEEDDDDDDDCEECDDDDDDDDDDDDDDCDDDD
@5AV
GTCGTCCATGTACAAGTACCCTTCTGACATCTCCTACATGCCTTCCTACCATGCCCACCAGCAGAAGGTGAACTTTGTCCCTCCCCATCCATCCTCCATGC
+
BBBFFFFFGHHHHIJJHHIJJJJJJJJJJJJFIJIJJJJJJJIJJJJJJJJJJJJJJIJIJJJJJJJJ@GHIHHHHHHHFFFFDDDEDDDDDDDDDDDDDD
@5AW
CCAGATGTCTGAGCCAAACATCCCCTTCCCACCACAAGGCTTTAAGCAGGAGTACCACGACCCAGTGTATGAACACAACACCATGGTTGGCAGTGCGGCC
+
CCCFFFFFHHHHHJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJHHIJJJJJJHHFFFFFFFEEEEEEDDDDDDBDDDDDDDDDDCCDDDDD
@5AX
CACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAAT
+
C@CFFDFFHHDFHJJJJJJJJJJJJGEIIJIJJIJJJJJJIJJIJIJJBIIJJJJJGIIIJHHFFDECDCDCCDDDDDDDDBDCD>CCDDDDDCDDCDDDD
@5AY
CTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCAC
+
CCCFFFFFHGHHHJIJJJIICHIIJJJJJIJJJJIJJJJJJJJJJJJJIJJJJIJIJGIIJIHHHEDFFFFCEEEEBDDDDBDDDDDDDDDDDDEEDDDDD
@5AZ
GTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACT
+
=:?D?DBDFFH?BDGEGGHEG?FHIGIA+<;FHG9FEGHIGIEIIIG9?FHDFG@GB;CF@FGC=CED?CEFDCEECCCBCACCDDCCCCCCCCBABBBBB
@5B0
GAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCG
+
1?1+4ADDAFDFACA>EGEBFC@<A@HDBE+:?FEGACFEF>GAFB</B>FF@==@FFFFIIII@EE>??>ECB?3?>AACB:>A>@>>B@AA@?BBBBB
@5B1
CTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTT
+
CCCFFFFFHHHHHJJIJJJJJJJJJJJJJJJIJIJJIJJIJJJJJGJJJJJJIJJIIJJJIJJIGHFFAEDEEDDDDDDDDDDDDDD@DDCDDDCDDDDCC
@5B2
GTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGC
+
@:;DD>?D><3CDF9C<CB<<<CGE@FHEEE>@>F;?DG3:;9;3?FF:@:BCFF;;@@ACEEEFF9A;@DDBDBA.;>B>;==5;(55(:A:@BBBB@
@5B3
GAAAAACGTCAAGCAGTAAACATGATGTGTCAGCACACCATGATTTGAATATTGATCAATCACAGTGGAATGAAATGTACATAAATAGTTCTCAGAGAGT
+
;1=?;:@DCBCDFGIA:ECBHHI@H9CEG:EEB<F@GIGGHIDHB<4*?F<?B88B<BBBF8BAC7@).@C@@@===..?=:;?B@DE;B>;CDCCAC@A
@5B4
AGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGAC
+
BC@FFFFFHHGHHJJJJJJJJIFHJJJJIJJIJJJJJJJJIJJJIJJIJHIJJIJJIJIJJJJIJJJIHHHGFFFFFEEEDEDDDEDDDDDDCCCBDDDBB
@5B5
AGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCT
+
CCCFFFFFHHHHHJJGIJJJJJJJJJJJJJJJJJIGHIJJIJJJJJJJJJJJJJJIJJJJJJIIJJJJJHHHHHFFFFFEEEEEDDDDDDDDDDDDDDEED
@5B6
GGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATG
+
BCBFFFFFHHHHHJIJJJJJJJJJJJJJIJJJJIJGJIJJJJIIJJIJIJJIIJJHHFFFEDDBDDCDDCDDEDDDDDDDDDDDDDDDDDDDDDDDDDDDD
@5B7
CCTTTCCAGATAATCAGCGTCCACTGCTGAAGACAGACATGGAACGTCACATCAACGAGGAGGACACAGTGCCTCTTTCTCACTTTGATGAGAGCATGGCC
+
CCCFFFFFHHHHHJGIGGIJJJJIGJJJJJIJJJIJJJJJJJIIIDHIJJJJIJJDGGJJJHHHFFEFF@CEEEEDDDDDDDDDDDDCCCCDDDDCCDDDD
@5B8
GTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGAT
+
CCCFFFFFHHHHHIJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJHHHHHFFFFFFEEEEEEEDDDDDDDDDDDDDEEEDDE
@5B9
GTGCAAGCCTATGTCCTATGAGGAGAAGCGGCAGCTCAGCTTGGACATCAACAAGCTCCTCGGCGAGAAGCTGGGCCGCGTGGTGCACATCATCCAGTCAC
+
@@@FFFFBHDBDDEBEDDIGEEDECGGEB@EHIIIGEBDGCFEHIIGIGAGCEHGII>ACHHFBCCBBCCCCCCBBBBB<9>>8<CCCC@>CCCCCCCCCC
@5BA
CCTGGCTCATCCCAGCAGAACAGAAGGCTGTATGTTTGAAAAGGGCCCCAGGCAGTTTTATGATGACACCTGTGTTGTCCCAGAAAAATTCGATGGAGAC
+
@@@FDFFFHHHHHJJJIIGGJJIIIJJJJJHIJIDHHIGIIIIIIIJJJIJJJJJJJIJIIIGGFHEHHHFFCFFEDEEEDDDDDDDDDDDDEEEDDDDD
@5BB
CTTCCCTTTCTCCCACCAACTTCTGACCCACCAGACCACCCACCCAGGGAGCCACCTCCACAGCCCATCATGCCTTCAGTATTCTCTCCAGACAACCCTCT
+
?@@FDFDFHFDDDIIIEHCGHHGGGIIGIGGIIIIF@GFGHEGGEGGGEGGBHGII;CEEB@BBECCCECCCCCCCCCCBA@CDCCCCCCCCBBCBBBBBC
@5BC
CTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGAATGGCACTGGTGCTTATGATACCACC
+
=814B?==ABDFDEA?FGDGAEGF9H>H<CCGADCG;?;D9*:?D?FFFI?=@7@EC.=66?15;?.6>6>@>8'39>:<BBBB?BBBBBBABB::AB>4<
@5BD
GAAAAGTGTGCTCTACAGAGACAGCTTGAAGACCTTGTTGAAGAATTGAGCTTTTCAAGGGAACAGATTCAGAGAGCTAGACAGACAATAGCTGAACA
+
CCCFFFEFHHHHHJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHHFFFFFFEDEEEDDDDDDDDD
@5BE
GGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACAC
+
CCCFFFFFFDHFHJJJJJGIJJJJJJJJHIIIJJJGHIGIIJJJGHJIIJJIGIIJJJIJJJJIIJIIFHHHHFFFFEDDEEDDDDDDDDDEDDCDCDDD
@5BF
AGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCAC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJIJJJIIJJJJJIJJJJJJJJIIJJIJJHGFFFDCEEEDDCCCDDDDDDDDDDDDBDDDDDDDDDDDDDDDDDED
@5BG
GAATTTTTGGGAAATATGAAAAGCCAAAATTTGTGCAGTGTTTAGCATTCTTGGGGAATGGAGATGTTCTTACTGGAGACTCAGGTGGAGTCATGCTTAT
+
C@CFFFFFHHGHHJIJJJJJJJIIGIJJIJJJJJJIJIFGIIGJIJJJJHIJJIJIGIFJIIIGHIIIJGHHHHHFFFFFEDEEE@CDDDCDDEDDCEDD
@5BH
CACCTGTGTTGTCCCAGAAAAATTCGATGGAGACATCAAACAAGAGCCAGGAATGTATCGGGAAGGACCCACATACCAACGGCGAGGATCACTTCAGCTCT
+
CCCFFFFFHHHDHIJJJJJIJIJJJJGIJJIJJIIJIJJJJJJJGJIJJJJJJJJIIGIIJJIHHHFFFFDDDEDDDCDDBBBDDDDDDDDDDDDCDCDDD
@5BI
CCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTAT
+
CCCFFFFFHHHHHJJJJJJIJJJIJIGIJJJJJJGIJJJJJJJJHIJJIJIHHHFFFFFEEEEEDDDEDDDDDDDDDDDDCDDDDDEDDDDDDDDDDDDDD
@5BJ
GGGGACACGTGAATATGGCATTCTCTCAGTCCAACCCTCCTTCGGAGTTGCACAAGGTCCACGGATCCAGAAACAAGCCCACCAGCTTGTGGAACCCAACG
+
=8+4:ABB?AADA>BB@EE?FHIDEHGECCEGFFFEFDEG@FAD@BFFBFFIFEE;@.=@EEEFEDDDCCCC>BBB=?BBBBBBBBABB2:?@ABBBBBBB
@5BK
CAGCGTCCACTGCTGAAGACAGACATGGAACGTCACATCAACGAGGAGGACACAGTGCCTCTTTCTCACTTTGATGAGA
+
@@@DDFFABFBHGBDDHHIIIIIIEH@GIIFBFHGIFHGIDGHGGA<DEEHGIIICCEECAEECECDBEDCECACCDC>
@5BL
CCACTTCATGTTCCAGTGCCTCGAGCGCTCAGGATGGAGGAAGACTCGATCCGCCTGCCTGCGCACCTGCGCTTGCAGCCAATTTACTGGAGCAGGGATG
+
@@<DD?DDBFDFFAFGIHFBH<C<@:@<FFDG;FEGI@FB7D>F;BFA?HIG@GAHHEHFHEEACBB?C@B@=@@@CC>?@CCC@:(+:@38???BB8?B
@5BM
CAGGAAAACACGACATGTGAATATCCTACTCTTCATGGGCTATTCCACAAAGCCACAACTGGCTATTGTTACCCAGTGGTGTGAGGGCTCCAGCTTGTATC
+
CC@FFFFFHHHHHJJJGIIIGIHIEGGGEHGIIIJICGIGHIJJIIJJJJFEIJJJJJGGIIIGGHHGHHHHFFEEFEE>?;?@CDDDDDDDDDCDCDAD@
@5BN
AGCGAGAACTGGGTGAGGGAGCCTTTGGAAAGGTCTTCCTGGCCGAGTGCTACAACCTCAGCCCGACCAAGGACAAGATGCTTGTGGCTGTGAAGGCCCTG
+
@?@D;@D:CD:<C+@AFH@FB8;BEEBB@@B3B?DHH900?@CFGAF56=FHHGAAEACHHEEECBB;;,9?99<<BC@AC@DC1:8?B7234((+28<1<
@5BO
CTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTAT
+
CCCFFFFFHHHHHJJJHIHIIJIJJJJJJJJJIJJJJJJJJ@FHHEHIJIIHEHFHHFFFFFFEEEEDDDDDDDDDDDFDDDDCBBDDDDBDDDDCBD?CC
@5BP
CTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTTATGGGC
+
@@@DDFDDFGHFHIJJJHFFHGIIIJJIIJIHIHJIIIIIJIIIJGGIEIGGGGG@;DGIIIHHHGHFDDDEDDDDDDDDDDDDDCDDDB9<<BCDCDDDA
@5BQ
CTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGC
+
CCCFFFFFHGHHHIJJIJIIJJJIIIJJJIIJJJJJJJJJJJIJJIJJJJJJJIGGGIJJJIJIIHEHHFFFFFFEEEEDEECDDDDDDDDDDDBDDDDC
@5BR
TAAAGACAACAAATGAAGTTCTTTTGGCTGTGGAGTTTCACCCAACAGATGCAAATACCATAATTACATGCGGTAAATCTCATATTTTCTTCTGGACCTGG
+
@@@;BDDDHBDHFBF<?EHEFGIIBHEIIEFFH9C9CDHFGIIEFEHIECBFFACHBCGEHIGCCHGIIG>BH<<?DCCCCCDCEDEDACCCCCC>999?@
@5BS
GTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTAC
+
@=?DDDDDAHDFF@E?GFGHH>FC:A??FEHDHDGGBFHGGA??DF=CFHIHCFIG@@CG@@;7ACEHEE@@C@>>CCCBBCBBB9@B?CBBC@?CA4>CA
@5BT
CCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGT
+
@@@DD?DDA>CFBHIEDC???DAGIGIIECGIHGEGGCHC>GHCD@FDGGGGCE>AAEEEDB?DCECCCC=??5>CC@CAB?88<CCABBBC<CCCCB??4
@5BU
CCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGT
+
CCCFFFFFHHHHHJJJJJJJJHIIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIIJJJJJJJIHFFDDEEEEDDDDDDDDDDDDDDBDDDDDDDDDDD@
@5BV
TAATAAGACAACACATGGCACAGATGGAGGAAATGAAAACACGGCATAAGGGAGAAATGGAGAATGCTTTAAGGTCATATTCAAATATTACAGTTAATGA
+
@@CFFFDFGGHHHFIJIIGIJJIJJIJJJGJIJIGIJIJHGHIJJGJJIIGIGGIJIJJHGFHHDDDFFFEEEE@CCCDFEDDDDDDEEEDDDFDDDEDD
@5BW
CCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCC
+
??8?DAA2C?D?CE:@DEEBEE<BE@DDDIIDIIII@>9DBE<9?D@ACDC)=3=(84===ADCD>?D;=>@?@??>;>5>>>>A><=:><>><>>A>:><
@5BX
GAGAACTCAGCGACACTACCTGGGCCATACAGACTGTGTGAAATGCCTTGCTATACATCCTGACAAAATTAGGATTGCAACTGGACAGATAGCTGGCGTGG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJIJJJHIHIIIJJJJIJJJJJJJJJJJJJJJJJJHHHHHFFFEFFEEEEEDDDDDDDDDDDDDDDDD<BD
@5BY
TGACAGTTCGACTGATGACTCTGAGGAGGAGCGAGCCCAGCGGCTGGCTGAGCTCCAGGAGCAGCTCAAAGCCGTGCACGAGCAGCTTGCAGCCCTCTCTC
+
@@@AAD+AFFFFDIB4EF9EHCEDHFFIIABG@FEF<FE;F@FF/=B1);;?>;AAAB@?B=??9?>@AAB((5&502:?9>-53+((98>@38<3239A:
@5BZ
CAAGTTTGTGTGTGATCCAGAAGCCCTTTTCTCCATGGCCTTTCCAGATAATCAGCGTCCACTGCTGAAGACAGACATGGAACGTCACATCAACGAGGAGG
+
@@?DBDDD?F?DFHGEH@BFGIIIIICGGIIIIGEGEHGGCHIIGEIBFGHGGEDGGGIIIIIIGDGGGCHAHEEEEDDECCCCBBBBC@CA@<;?BBBB9
@5C0
CTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGC
+
CCCFFFFDHHHHHGHJJJJIJJJGJJIJJJJJJJJIJJJJJJJJIJIJIJJCHJJJJJGIJJIIJGFGHFFDBEFEEEEEEEDDDDDDBDDCCDDDDDCD
@5C1
TGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACAC
+
@@@FFFFFHAFHHGIIIJJIJJJJIJIJJGHGGGIIEBFDEHFHHIJJJJJIGJIIFHIJJIIIJJIIHFHHHCDFFFCDDCDDDCABDCDDEEDDDDDDD
@5C2
CTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCT
+
:??::=B?DFDBFFEGBGCCFECEFEGIIFBFFFG?FGIIIIEFCGIDEECFFECFCDDD=AEEFEECFDEED>BCB@A;ABDBBE<AB:@A>BA@BBABB
@5C3
GGAGTTTGAGGCTGAGGAGATGCAGATTCAGAACACACAGCTGATGAATGGGTCTCAGGGCCTGTCTCCTGCAACCCCTTTGAAACTTGATCCTCTAGGGC
+
?@;DBDAD8DFFBFIB@??GAHGGIIGIII<CGBFHGIBCEHIIEEHIIIGE=B>C<8=FA;CG7@CEA>ACDD@D>BAAACCCC:;AAC@CA@>5>AC??
@5C4
CTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCT
+
CCCFFFFFHHHHHJJJIJJJJJJJJJJJJJJJJJJBFHJIJIJJJJHHIJJIHHGHGHFFFFFDEEEEDDDDEDDDDDDDDDDDDDDDDDDDDDDDDEDDD
@5C5
GGGAAAGTGGCATGGTGATGTGGCAGTGAAAATGTTGAATGTGACAGCACCTACACCTCAGCAGTTACAAGCCTTCAAAAATGAAGTAGGAGTACTCAGG
+
@?@DADEDDDDAFGG<CAEBHGGGIF+ADCHIEEDH<?FHCF@AHICHEGG@@GIFICBEDC;ACCG>DHDGH?A?EA@BB;7>CA6;>ACC=;@CC@:A
@5C6
ATCTGAATCCAGAAAGGAACTAGAATTAAAACATGAAGCAGAAGTTACAAATTACAAGATAAAACTTGAAATGTTAGAAAAAGAAAAGAATGCTGTGTT
+
CCCFFFFFHHHGHJJJJJJJIJJJJJJJJJJIJJJJJJIJJJIJIJJJJJJJJJJJJIIIIJJJJJJJJJIJIGIIJJHHHHFFFFFEDEEEDDDDDDD
@5C7
CCGAAACCTGACCGGGCCTTCCCAGCTCACCTCCCTCCATCGCAGTCCATACCAGATAGCAGCTACCCCATGGACCACAGATTTCGCCGCCAGCTTTCTG
+
CCCFFFFFHHHHHJJJJJJJJJIJJJJJJIIJJIJIJJJIJGIJIJGIJJHHHGHFFFFFFCEEEEDDDDDDDDDDDDDDCDCDDCBDBDDDBDDDCCCD
@5C8
GCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGC
+
CCCFFFFFHHHHHJJJJJJIJJJJJJJJJJJJJJJJJJJHIJJJJJJJJJJJIIJIJIIIIIJIJJJJJGHGHGFFFFFEEEEEEDDDDDDDDDDDDDDD
@5C9
CATTAAACAAAGAGATGGCATTATAACCCAGCTCACTGCTAATTTACAACAAGCAAGAAGAGAAAAGGATGAGACAATGAGAGAATTTTTAGAGTTGAC
+
CCCFFFFFHHHHHJJJIJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJIIJJGIJJGIJJJJIIJGHHEHHFFFFFDEEDEEDDDDDDDDCDDDD
@5CA
GCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACC
+
CCCFFFFFDDFDFBBFGFIGHBE@HGIGIEFHIGIICE@FDEGIIIAGHHICCGGHGHFH@DGGHFHHHFBB@>6A@CECCACC@CCCDDDDBAAA>CCB
@5CB
GTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGC
+
CBCFFFFFHHHHHJJJIJJJJJJJJJJJJJJJJJJJJJIIJJJJJJJJJIJJJJJJJJJJJJJHHHHEEFFFFFEECECEDDDDCDDDDDDDDDDDDDD
@5CC
CAAGGCTTTAAGCAGGAGTACCACGACCCAGTGTATGAACACAACACCATGGTTGGCAGTGCGGCCAGCCAAAGCTTTCCCCCTCCTCTGATGATTAAAC
+
@@@DFFFFHABFHEBFEBFFHIIIGIIIIIIBGB?DHIIIGHGII@BFHHII=FGB>EAEH;BFDBDD=?5<<CC@>CDDDDBBBDC9:CCDC>B>CDDD
@5CD
CCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACA
+
@@CFFDFFFHHFHGHHGGIJJEHIEIGIIIIGHHBGGHGIIGIJGEHIJJIGIIGIJHIIGIGIEEEFDEEEDDDCACCDDDDCD@CCDDCCC>:>ADCC
@5CE
CTCAGCGACACTACCTGGGCCATACAGACTGTGTGAAATGCCTTGCTATACATCCTGACAAAATTAGGATTGCAACTGGACAGATAGCTGGCGTGGATAA
+
@?@?ADD?FFDAFHEBG@FHGGD?DB?BGHG9?GHAHI>B<F@FEHBFFEHIAB@FAF@DCEAECEC;3A?@D@CBAC@6>>;;>CCCCCA<83098>:@
@5CF
CCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGC
+
CCCFFFFFHHHHHIJJJJJJJJJJJJJJJJJJHIIJJJJJHIJJJJJJJJIJJJJJHIIJJJJJHHHHHHFFFFFDDDDDDDDDDDDDDDDDDDDDDDDDD
@5CG
TGAGCATATGCTTACTGTATGGGACTGGCAGAGGAAAGCAAAAGGAGCAGAAATAAAGACAACAAATGAAGTTGTTTTGGCTGTGGAGTTTCACCCAAC
+
CCCFFFFFHHHHHJJJJIJJJJJIJJJIFJJJJJIJJJIJJJJJJGIJJJJJIIJJJJIIJJJJJJJHHEHEEFCFFFEDECD?CDCBACDDDDDDDDD
@5CH
TACAGCTTTCAGTCAGATGTATATGCATTTGGAATTGTTCTGTATGAATTGATGACTGGACAGTTACCTTATTCAAACATCAACAACAGGGACCAGATAAT
+
@@@DADDDFB<?HGGGAEHCIFCDHEHGHHHEFGHIIFBDGIFGFGGGIIEBDFHHFDAEDDC/?FHBFDBFBHIGIEFGGEEGEHCHEEE;??=>BCCFC
@5CI
TGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGC
+
@@@FFFFFGHGHHIIIAGGIGHGIEHGEG@HHICHHGEBB@GGGGEGGIIIBGGIJJIGGIIG@DEEHEHFFFDFECCACEACCDD;CA:?AC?AB>>B@
@5CJ
CTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCC
+
CCCFFFFFHHHHHIIJJJJJJJJIJJHIJIJJJJJJIJIJJJJJJJHHIIIGIJJFHHGIJHGHHHFFFFFEDBEEDBDBBDDDDBCDDDDDEEDDDDDDD
@5CK
CAGGGACTTCAGACATTAACCATGACAAATTCAGGCAGTACTCAGCAAGGTACAACTATTCTTCAGTATGCACAGACCTCTGATGGACAGCAGATACTTGT
+
1;?ADD1B?DDBBCD9@ECCEFCEADEB?++1?CA9CD3?99?DD:?;D<00/9B9?<<=C:@==@77;A7=47776(=3)?;);7)(.;(6=3(5(5;:(
@5CL
CTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGAACCTGGGAGCTAC
+
:??D>AD?>;A+<?BBEEE<3C4C<<EEE9C;E@6@DB<9?-<(=@C9=;;;?>=;A=AD@A;??@@AA>A>;;;>>;AA>AA??(8(2<<9<((+2.8AA
@5CM
ATTGGGAGATTCCTGATGGGCAGATTACAGTGGGACAAAGAATTGGATCTGGATCATTTGGAACAGTCTACAAGGGAAAGTGGCATGGTGATGTGGCAGTG
+
CCCFFFFFFHHHHJJHGGIJJJJJJJJJIJFHIIIIJJJJJJJJJJIGGHIJJJJIJIJIJIJJIJHIIIHHGHHFFFFE@;C?CDDD;AACC@CCDDD<A
@5CN
ACTTCAGCGGTGGTCCAGATTGATGGCTAGGATTGTTGGTTAGTAGTTCCTTGAAACAATATTGGGGATTTATGGAGAAGCGGATGCGCCGCCTGGTGTGT
+
(-02-2.)((0(02):)).2)))2)))2;(33<=<:86((()0.).<9)3)/)/))))()).8399'(')...8=1=(.((,'',',5&)&&&&((+(22(
@5CO
GAAAACCAAGTCATACCAGTGCTGTCTCAATTGCAGGAAAAGAAACTCTTTCATCTGCTGCTAAAAGTGGTACAGAAAAAAAGAAAGAAAAACCACAAGG
+
CCCFFFFFHHHGHJJJJJJHIJJJIJJJJJJJIJJJJJJJJJJJJJJJJJJJIJJJJJJJJJIJJIJFHGCHIJIIJHHHFDDDDDDDDCDDDDDDDDDD
@5CP
ATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJIJJJJJJJJJJJJIJJJJHHHHHHHFFDEFFEEDEEDDDDDDDDDDCDDDDDBBDDDD
@5CQ
CCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGAAGCAGCTACGGGCAGCAGAGTTCATTCCGTCAGGACCACCCCAGCAGCATGGGGGTTTATGGG
+
;???1B?3=CD31<E3+A:A4?FDBEE<A<+CC;;39)1?D;0)?<??:06@@1@;CA.)).7??A3.(;'((;==?>>8=<(5,9(54<>(050<9:(4(
@5CR
AAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTAC
+
@@@DFFDDHFHHHG9BGIIGFEFEADACFGGHGIGGGGDFHHGGG@;@FDHD=HC=CEFDDDECCC>;>CCDA>C7:>(5>>@@>:C@CCACC@?C8?+>@
@5CS
GGACTTGGCACTTTTGAGCGTGGAGTAGGATGCCTGGATTTTTCAAAAGCAGATTCAGGTGTTCATTTATGTGTTATTGATGACTCCAATGAGCATATGCT
+
@@BFFFFFHGHGHJJJIJJIFHIEHEGGIIJIJJJJJJJIIIJIIJIJIIJJIIJGIJIFGIGIJJJJHGG>CHGFFFFFDCEEEDEECDDDDDDDDDEDE
@5CT
CCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGG
+
@@@ADDFFGFBFHIIIIGCHIGGHIEHIGI:?FGIIIIIIEHIIIGEHGGDGHHGGIIIGGGGEEED@BFFFEEEDDDDDBDDD9ABDDD<@?@ACCCDC?
@5CU
CCTGTGGCCACTCTATCCAAGCCTTCCCTAGGTGACCGCTCCAAAATTTCCAAGGACGTTTATGAGAACTTCCGTCAGTGGCAGCGTTACAAAGCCTTGGC
+
CCCFFFFFHHHHHJJJJJJJJIJJJJJIJJJJGIIJJIIGJJIJJHIJJIJJIIJGIJJJHHHHHFFFFFFFEDCEDDCDDDDDDDDDDDDDDDCDDDDDD
@5CV
GATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGC
+
@?@FFEFFHHGGHJJJIJJJJJJIJJJIJHHHIJGHEGICECHHFGIJJGEHIJGGHHFFFFDCDBCCDDCDDDDDDEDDD>A?CDDDDDDBDDDCEDDD
@5CW
CTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTT
+
CCCFFFFFHFHFHJIGGACIHHIGIJJJGIIJJJJIGIJGIIJJ?FHGIJIIJJCHGIGIJGHJJJGHHHHFFFFDEEDCDDDCCCDDDDDDDDDDDDDCD
@5CX
GTTCCTCAGGGCCCATGGGCCAGATGCAATGATCCTTGTGGATGGACAGCCACGCCAGGCCAAGGGTGAGCTGGGGCTCTCCCAAATGCTCCACATTGCC
+
@??B?BBB:+22CG;F;E;CCCDC??E<?EGDF<D<CFBBDBF@=>BDDFC8CF;@;@E2-?AB?=.5=B;>A=?BB@@9A>A???ABB44:@9>A@B>@
@5CY
TCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCT
+
C@CFFFFFFHGHDHIIJJJJJJJJIIJIJJEHJJIJHIIGGIGIIJIJJIJGIJIIIJJIJJHGHHFFFFEEECE6>C@CDDEDDDCDDBDCCCACDDDDD
@5CZ
GAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACT
+
CCCFFFEFHHHGHJIJJJJJJJJJJJIIIJIIJJJJIJJIJIIIIJJJJJIJJIIJIHHJGIHHHHFHEFFFFEECCCBDDDDDDDDDBDDDDDDDDCDD
@5D0
GGGACCCAGGCCGCACCAGGAGAACAACCACCAGGAGTCCTACCCTCTGTCAGTGTCTCCCATGGAGAATAATCACTGCCCAGCGTCCTCCGAGTCCCACC
+
B@@DFFFFHHHGHJJJJJHIHIHIJIJJJJJJJJJEHCHIIJJJJJGGIGHHH?ECACFDFFFEECCCDDDDEDDDDDDDDDDDDDDDDDDDDD@CDDDDD
@5D1
GGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCT
+
=;?DDDDDHHFFHGJJJIFEFGGIGEDEHIJIGCFHGGAAHIIIIIJJIJJIGJJJJGEIJJJJJJCHHCHHHGGCFFFFDEE>CD?ABDCDDDDCCDDC
@5D2
TGAAATGTTAGAAAAAGAAAAGAATGCTGTGTTAGACAGAATGGCTGAATCACAAGAAGCTGAATTAGAGAGGCTGAGAACACAGCTTCTATTTAGTCACG
+
1++<A;A4<,?>B<3CAABBB>A>+<@@BCB7@9=*14?=AB<A)?A;7?A?BA<2.>==>A>B)=A;.4)-5A;;;;>>>@@:>(55;3;;>??>(:=96
@5D3
CAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJIHIJJJJJJJGHGHHHFFFFEEEEEEDDDDDDDDACDDEDDDDDDDEDDDDDDDCCDDDD
@5D4
AAACTCTGCGTCTGCTTGGTAGTGGAAAACATGGAGAAATCTCCCGCCATGACCACAGCCAGCTGGAATAAACAAAGACACTTATGTAAATATTCCTAGCG
+
3;<5())))((0(2:18.(2))2)6))).1:<)))()(0.)))))(0''-))))).6(66(.-.))(.(((6((((-((-((((,(((((((((+((((+)
@5D5
CAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCA
+
@C@DFFDFHGHHHFJJGIIIJJIJIIIIICHJJJJIIGIIIJIGIGGGEHIJIJIIIJGGIJIIIEHHEHFFDDFFFEEDCEEDDDDDDCDBADCDDDDD
@5D6
GTGAGATGGATGCTGTAGGCTTGGAGCTGCCTGTACAAATAGAGGAGGTCATAGAGAGCTTCCAAGTTGGGAAGTGTGTAACTGAGTATCAGGAAGGCTGC
+
@?@FFFFFHFHHHJIFHIIIGIJGCEEGIGIJE?C@FD?FBHDBDBDA?FFHHII@ABEE@=@FHIGGG)56.;.?.?@@>CEECC>AA>>C3;AA@BC<@
@5D7
GGCAGTGAAAATGTTGAATGTGACAGCACCTACACCTCAGCAGTTACAAGCCTTCAAAAATGAAGTAGGAGTACTCAGGAAAACACGACATGTGAATATCC
+
CCCFFFFFHHHHHJJJIJJJHHJJJJJJJJIJJJIJJJJJJJJIJJJJJIIJJJJJJJJJJJJJJGGIIIJIJJIHHHHHFFFFFDDDBDDDDDEEFEEEE
@5D8
ATGTACCAACGCCAGATGTCTGAGCCAAACATCCCCTTCCCACCACAAGGCTTTAAGCAGGAGTACCACGACCCAGTGTATGAACACAACACCATGGTTGG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHECFFFFDDDDDDDCDDFEEDEDDDDDDDDDDDDD@CBD
@5D9
AGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJGIJJJJJJJHIIJJJJJIIJJHHHHHHFFFDDEEEDDDDDDDDDDCEEDDDDDDDDDDDDD
@5DA
CACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCA
+
@@CFDABDCBBAFBGHGHIBHF7DHGIDHIEGE@EHFHIIGD>DBDGCDBGDEBHEICDEA>EEHE@?D@77A>A5;;ACA?CB<>?:@AAACACCC>C@
@5DB
AGTCGAGAAGGGCTAAAACTGGATACCAGTATCAAGAACCAGACGCAGCTGACTACAACCTGGCTTCGCTGAGCAGTACCTTGTCCCCAGATTAGAAAACG
+
:+12?<AA8A+<772<+<+3?>?@A=ABB1?411?<ABBB9=A))<4<0>AA)8A)7)7=36>=);>=396';3;;(,595(9((,,2(8;?3(5+((+39
@5DC
CGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAACCCACTGATGTCAGCTATACCCAGGCTC
+
>+=7<7+AC+AC3A@B@@<+<22<?BB7*11?===;;;A2A>???(9AAAB5.)=>B;BABAA;>A=3)>>>(.,=;==;5;9,,5;?5,(5;9??1((+8
@5DD
TGGGCTCCAGGGGCAACATTTCCCTGGGTCCTGGAGAAACCCTAGTACCTGGGGATACGGAGAGCAGTGTGATTCCCTGTGGAGGCACAGTTGCGGCAGCT
+
@@CFF>DFHFFFFDECAEF<CDHIHF?;)??FGAGIDF>DGCFBGFH<FEIEIGGGGGGFEEBBBCCAE6>CDD;@C>C>AC:A?7?<CC@CCCCC@@B89
@5DE
CAAGAGCCAGGAATGTATCGGGAAGGACCCACATACCAACGGCGAGGATCACTTCAGCTCTGGCAGTTTTTGGTAGCTCTTCTGGATGACCCTTCAAATTC
+
CCCFFDFFHHHHGJJHFDJGIGIJJIIGIIJJJJJJJJGJJEGIFHFDECEECDDDDDDDDCCDDDCDECBDD?CDCDCDDDDDDDDCCDDDDDDDDDDDC
@5DF
AGAACAGGGAAGCAGCTCGAGAGTGTCGTAGAAAGAAGAAAGAATATGTGAAATGTTTAGAAAACAGAGTGGCAGTGCTTGAAAATCAAAACAAGACATTG
+
CCCFFFFFHHGHFGIIIGIGIEH?ECCFFGHIIJIGGGIGHGEHEIIIHGGIJIJIJJIIIJIJIHHHH@DDFFD;@>@CCBCCCA>@CDD9?B?99A>@A
@5DG
GTGAGATTAGTTTTCTAAATGAAGAAGTTAAATCTTTAAAGCAAGAGAAAGAACAAGTTTCATTGAGATGTAGAGAGCTAGAAATCATTATTAACCAC
+
B@@FFFFFHHHHHJIJJJJJJJJJJJJHHIJJJJJJJJJJJJJJJJJIJIIJJJJJJGGIJIJJIGIJIJAGGJJJJJJIHHHHGHFFFFFFFECEED
@5DH
CTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACCAGTTATGATCAGAGCAGTTACTCT
+
?@@7:ABD><CD8EE>:;:C?<AA<?*@??B@DAAGGFCCF39BFFDD(9BEDFEFF=@@7@)=)@@)))6;6''3',,;:((5(5,5>@:?A34:>>@:(
@5DI
CAAGAATGCTACTCCCACCAAAAGCATAAAACGACCATCACCAGCTGAAAAGTCACATAATTCTTGGGAAAATTCAGATGATAGCCGTAATAAATTGTCG
+
@@@DDFFFHHHGHJIJJJJIJIIHGHHJJIJIGIIIIJJJJJJJIGIJJIGGCEHIIIJJJJGIHHHHHFFFFFEEEDCCCDDCDDDDBDBEDDEECDED
@5DJ
GTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACA
+
;@<BD?>BFDDFAGHIFIIHIIGHG@GCHCHGI9?CFD<BBF>@8BFBGFDDG>=CEHGAHIIDHICECE;;?C<BCBACBA@C;=AB?CCCCCCCCCC
@5DK
AGAGAAAGTGCCTGTGAGGCCCAAGGACCCTGAGGGGGTTCCTCCTCTCCTGGTCTCTCAACAGGCAAAACGGGAGGAGGAGCGCAGCCCAGCTGCCCCAC
+
??@;DDBD+=C:CBABEGFIIIIIED@?EECCDDFD>BBEEFEDFBD;@EC>A=?;B;B@@;A@9?BBBBB?BB?B<??<8(29BBBBBB8?BBB>@BBBB
@5DL
GGATGACTCAGTGCTGGCAACATCAGCCTGAAGACAGGCCCAACTTTGCCATCATTTTGGAGAGGATTGAATACTGCACCCAGGACCCGGATGTAATCAAC
+
CCCFFFFFHHHHHJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJGHIJJJHHHHHHFFFFFFEEDDDDBDDDDDBDBCDEEEDDD
@5DM
GTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACA
+
CCCFFFFFHHHHHJGJJJJJJJJJJJJJIJJIJGIJJJJJJJJJJJJJJJIIJIJIJJJIJIJJJJJHHHHFFFFFEEEDDDDDDDDDDDDDDDDDDDD
@5DN
TGGAGTTTCACCCAACAGATGCAAATACCATAATTACATGCGGTAAATCTCATATTTTCCTCTGGACCTGGAGCGGCAATTCACTAACAAGAAAACAGGG
+
CCCFFDDDHHHHHJJJJJJHGIIIJJIJIJJJJJJIJJIJJJJ:FGHGGGGIJJJJJJJ4BGGIJIIGIIICEFFF@BDCDDDDDDCCDDDDDDDDDDDD
@5DO
CTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATG
+
CCCFFFFFHHHHHJJIJJIIJJJJJJJJJJJJJIIJJJJJJJJJJJIJJJHHHHFFFFFEDEEEDDEDDDCDDDDDDDDDDDDDDEDDDDDDDDDCDDDDD
@5DP
GGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGC
+
@BBFFFFFHHHGGIIJIIJGIGGIJJJJ>FHIIIIJJ@GIIJGIJJIJJIIIJIJFIJJJJGGGGFFFFEACEEECDDD>BDBDDDBB>CDDACCCC@ACC
@5DQ
GCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGC
+
<@@BBDEDBDFHHIIBGHHIGDEHDHGIIIIFHIGBCBGDFFCGEEFFBGGGH@FA6@CEGEA=?=ABC@CD)?AC>A?B35?><A???AC3=<>@<<<
@5DR
CACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGG
+
CCCFFFDFHHHHHJJJJJJIJJJJJHJJIJJIJJIIHIJIJJIIJJJJJJIJJJIIJJHJIIGGGIHIGHHHFFFFFEDEEDDDDDDDDDDDCCDDDDBDD
@5DS
GCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGT
+
@C@FDEFFBHDBHIIEEDGBHIIIIGGIIGIDGID@FHIGIGBDHIGBBGDGAEHIIGE@HGGIEGHHCEEFCCCCCCCCCCCCCCBCBCA4@CCCCCCC@
@5DT
CCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGC
+
@@@DDAADHFHD??FEDBCFCHB<CAFAF?BFI@FGDBED@DBBGBBDFGCACHEH@;F@AGCECEHE?EBDEDECCC?@BA<:@CCCCCCCCCAAAACB8
@5DU
CACACGCGTGATCCAGCTGATGCCCAGCCCCATCATGCACCCTCTGATCCTGAACCCCCGGCACTCCGTGGATTTCAAACAGTCCAGGCTCTCCGAGGACG
+
CCCFFFFFFHHHHJJJJIJJJJJJJJIJJJJJIJJJJJJJJJIJJJJJJJIJJJJJHHHFDDDDCCDD9?BBDDDDEDDDDDCDDCCDBDDCDDBDDDDDD
@5DV
TACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJIJJIJJIJJJIJJJJJJJJJJJIJJIJJJJJHHFFFEEDDEEDDDDDDDDDCDDDDEDDD>CCDDDDDDD
@5DW
CTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTC
+
CCCFFFFFHHHHHJJJJFHIJJJJJJJJJJJJJJJJJHIJJJJJJIJIJJJJJJJJJJJJIJIJHJJJJHHHHHFFFFFEEEEEEDDDDDDDDDDDDDDDE
@5DX
CACAACACCATGGTTGGCAGTGCGGCCAGCCAAAGCTTTCCCCCTCCTCTGATGATTAAACAGGAACCCAGAGATTTTGCATATGACTCAGAAGTGCCT
+
@@@DDFDFHHFFHIHIIGCBHFHIIIIEGGHHGEHGDHIJGIIGIGHIIEHHGGHGHEF>DDD=@CCCDBBB?CCCDDDDEEDDEEDCCC>CDA>ACAC
@5DY
CCTCACTCATCAACAGCAGCTTGAAGAACAAGACCACTTATTAGAAGATTATCAGAAAAAGAAAGAAGACTTCACAATGCAAATTAGTTTCTTGCAAG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJIJJJIJJJJJJJJJJJJJJJJIJJJJJJJJJJJJIJJJIJJJIIHHHHGHFFFFFFEDEEDCEEEDDDDCDD
@5DZ
CGCGGTGTGGTGGCAGCAGGCGCAGCCCAGCCTCGAAATGCAGAACGACGCCGGCGAGTTCGTGGACCTGTACGTGCCGCGGAAATGCTCCGCTAGCAATC
+
=+1<A0<0++22;AB==A+?8<AA??AAB=AA=A>ABAAABB4>;=6=A/<@=;=57=5;?<8;7;:;38:??7<<;<;953999?=8(8:09;;9???:=
@5E0
CAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTG
+
@CCFFFFFHHGFDHJIJGIIJJJJIJIIJJJJIIIIJIJHIIIJJIJIIIIJJJIJJEFHED>DFFFEDDEDDDDDDCCDDDCDDDCDDDDDDDDDDDBC
@5E1
CGATGGAGTGGGTCCCATCAGTTTGAACAGTTGTCTGGATCCATTTTGTGGATGGCACCAGAAGTCATCAGAATGCAAGATAAAAATCCATACAGCTTTC
+
>==A+0+<?=AB0=?=B7@AA+>7=<>2:=:@@A*?:?<??7?ABBBB59==>A(>3==26=;)7=A>7)7=>73=?@;;)>@@@@@>9-5;>?=:3;95
@5E2
CTGTTGCACCGCTCCAGGTCACCTATCACGACAAATCACCGGCCTTCTCCTGACCCCGAGCAGCGGCCCCTCCGGTCCCCCCTGGACAACATGATCCGCCG
+
CCCFFFFFHHHHHJJJJJIJJJJJJJJJJJJJJHIJJJJJJJJJJJJJJJJHHHHHFFDDDDDDDDDDDDDDDDDBDDDDDDCDDDDDDDBDDDDDDDDD9
@5E3
CACCAGCAGAAGGTGAACTTTGTCCCTCCCCATCCATCCTCCATGCCTGTCACTTCCTCCAGCTTCTTTGGAGCCGCATCACAATACTGGACCTCCCCCAC
+
CCCFFFFFHHHHHFFIJJJIJJIIIJJJJJJJIJJJJJJIJJJJJJIJIHJJJJJJJIJJJIIJJJJJJIIHHHHEFDDDDDDDDDDDEDDDDDDDDDDDD
@5E4
CGGGGGTGGGGGGGTGATGGGGGGAGGCGTGATGGGGGGATTTCAGTGGGGTGGAGGGGGGGGGGTGGGGCGGGGGGAAGGGGGGGGGAGGGGGAGGGGA
+
00-2((0-0(;01&&)(+(+/(00&&&(&)1((5((+&&&&((((+(568&)&&(+(&0070&&)088&&&)&&&05&&+(0)5&&&)&)5&&&&)&)0)
@5E5
ACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGC
+
CCCFFFFFHHHHHIIJJJJJJJJJJJJJJJJJJJJJFHGIJJJJJJJCHIIJHHHHHHFFFFFDDEEEDDDDDDDDDDDDDDDDDDDBDDDDDDDDDDECC
@5E6
GAAAAAGTTACAGAGGGGGGTAAAGTAGAAGAAAATGTGCAAGTGGGGAAGAAGTGGGGAGAGTTGAAGGTATTTGGGGAAGGAATTCAAGATCTAAGA
+
0;(53((2)2).)))((((&*&((5(+((+(((2+3(+((++((+((&+&2(((+(++&+&)(+(+(((++(((((+))(&+(6(((+((((+(+((((
@5E7
CAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGC
+
CCCFFFFFHHHHHIIHJJJJJJJJJJIJJIIJJJJJJJAGHGJIIIIJJEHHHHHHHHFFFFFFDDDEDDDDDDDFDDDDDDDDDDDDDDDDDDDDDDDD
@5E8
TCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAA
+
??@DDBDDAHDACGAH;GCHBAHHCDBGC;?C::DB???F?BG@BGBF>FH88=88=CFI;E=549B666>C;(>;A;9<59,(,,,(,5:>::>A:42
@5E9
GAAACCCACAGCTGCAGAGATCTCTGTTCGAGTCCCTAGAGGGCCGGCCGTGGAAGGGGGACACGTGAATATGGCATTCTCTCAGTCCAACCCTCCTTCGG
+
7?@DDD?BDF?FBFEH@HIEDEDHG<FFCFH>CGIBC>D??DABC6<ABH::?BB@1<'38?1<;?BBB:@:>CBCC@::@CCA>C@>A:99@???3>A<0
@5EA
TGTACTGTCCCACCTAACGTTGCAACTGGGAGACTTCCGGGGGCCTCACTGCTCCTAGAGCCCTCTTCGCTGACTGCCAATATGAAGGAGGTACCTCTGTT
+
@@@DDDDDHDHHFIIIAB?AAGAHHGIIEDDFAGEHGHIEGGHBDCCCCCCCCCACCCCCCBBCBCCC<9999ACACACCA:CC@DCCBBB2>CCCCCCCC
@5EB
CGACGAGCTGAGCCACGCCGCCCGCGCCCCGGACGGGCCCCGCCACGCCGCCGGCGCCGCCAACGCGGAAACCGCAGCCGGCCCGCGTCGCCCTGTCAACC
+
;89@30-/(6)..;)):-8(<53059-';6=8,93'',,6:-&)7-70+)))&&)7)7&))&56+550&0&(+55:&&()85500&&&&&&+5:/:(((5:
@5EC
GGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTT
+
@@@FFFBDFHGHHIJJIGIEHIJJJIJIJIIJEHGICH@HBGGHIJJGIJJIJEIGJIEGGHIIJJIHHHGGFC>CEEECA??BD@BDBDD>DDDDCDDD
@5ED
CTTGCAGCTCCACAGGGAACTCCGGGACCCTTGGGTGTGGAGAGGAGAGGGTCTGGGAAGGTTATAAACCAGGTATCTCTACATCAGGATGGCCATCTAGG
+
CCCFFFFFDFHHHIIJJJJJJJJJJIHIIJIJJJJBFFGGHJJJJHHIIHHCHFFFFEDDDCDDDEEEDDDDDCCDDDCEEDDCDDDDDDDCDDCDDDDDD
@5EE
GAGCTTCATTTGCAAAGAATAAATCCAACTACAGTGAAAATGAAAAGTTCTGTCTTTGATGAAGACAAAACTTTTGTAGCAGAAACATTGGAAATGGGTG
+
@@@FDDFFHHHDHIGDEHIHIGGEIEFHIIJJJIIJJJJJJJJJGIEDHHBGDFHIICHGBHIHJIJJJGIJGIIIIIIIIEHHHFEFFFFCEDEDCD?B
@5EF
GTGAAATTTCAACCACAGCAGATGACTGCAGTTCAGAGGTAAATGGTTGCAGTTTTGTGATGAGAACAGGAAAGCCTACAAATTTATTAAGGGAAGAAGA
+
??:DD?DDDDBBHGB?EFHCEC@C?CHEE>EFH<:C?CG:C4DCGDHGF9B@FHIGHFHE<B)=FHGGIFII;C;;A>>BDD>ACCDCCA>@??BBBCC:
@5EG
GCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGC
+
CCCFFFFFHHHHHHIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJIJIJJIJIJJHHHEHHFDFFFFFEEDDDDDDDDDDDDDDDDDDDDDDD
@5EH
CAGCAGTCTCTTGTAAATTCAAAGTCAGAAGAAATGACTCTTCAAATCAATGAACTTCAAAAAGAAATTGAAATACTCAGACAAGAAGAAAAAGAAAAGGG
+
CCCFFFDEFHHHGHHIJJJJJJJGHJJJJIIJJJIJJJJJJJIIJJHJJJIIJJJJJJJIJJIIIIJGGHIJJGIIIIJGHEHHGFFFFEEEDDDDDDDDD
@5EI
TTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGC
+
?=;:DDDDB?:DFBFCFEFHAA?@F@:AFHBFCHE>GA@EHIG@B@?FAAFGGFCCAH)@;CACEC???);3;?;.6>;>;AB?(59?:35@>AAC9<?A?
@5EJ
CAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACC
+
CCCFFFFFHHHHHJIJJJJJJJIJJJJJEHIJIJJIJJIJJJJJJJJJJJJJJJJJJJHHHHHFFFFCECCECDDDD=BCDDDDDDDD:CCDDDDDDEEDD
@5EK
CAACACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCC
+
@CCFFFFFHHGBHIJJJJIIJJIJJJJGHJIJJIJJGJGIGIIJIIFGIIIJJJEIGEDHIIJGGAC@CEHHHHFFDFFCC>CEDBCBDDBDDDBBDBDB
@5EL
CGCAAAATCTAAAAACATATACAAAAGAAGCAAGAATGAAAAACAAGGGCGGAAGTCAAAATAGGGACCACTGCGAAGGGGGCCCCTGGAGAGAAGTGG
+
0((:9/9)91<))))(()3.)4;4)2)-(23<3))98)).):((((.(((-:;''.((6=<79(((((,(((,,'0&)0)5008:9/2+8/(+(3((+(
@5EM
CCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTTATGGG
+
CCCFFFEFHHHHHJIJIIHCHIJIJJIJIJJJIIIFGGJFIIIJJIJJJJJJJGGJJJIIJFHHHHHFFDDDDDDDDDDDDDADDDDEDDD3<<BDDDDDD
@5EN
GAGCCAAACATCCCCTTCCCACCACAAGGCTTTAAGCAGGAGTACCACGACCCAGTGTATGAACACAACACCATGGTTGGCAGTGCGGCCAGCCAAAGCTT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHIJJJJJIJJJJIIEHHHHHHFFFFDDDDDDDDADDDDCDCCDDDDDDDDDDDDDDDD
@5EO
CGGCAATTCACTAACAAGAAAACAGGGAATTTTTGGGAAATATGAAAAGCCAAAATTTGTGCAGTGTTTAGCATTCTTGGGGAATGGAGATGTTCTTACTG
+
@@@FF?DDAFAFFEA>ABBGGEGGGHIEHIIIIIIIDBHGGCH@DHHIIGIGIIIHIIE4@DGG;7=>CHE>BCB;@DFC=>?@ACCCB9A>ACAA@@@AA
@5EP
CAACAAGCTCCCCGGCGAGAAGCTGGGCCGCGTGGTGCACATCATCCAGTCACGGGAGCCCTCCCTGAAGAATTCCAACCCCGACGAGATTGAAATCGACT
+
CC@FFFDDHHHGHIJIJJGJJGGIJIGEHGFIEFFFDEEEDDDDDDDDDDDCCBBBB<@BDCDDDDDDDCDDDDDADDDDDDDD>@@BDDDDDDCCDDBBB
@5EQ
GTGACCATGACAAGCAGGGGTGCTGAAGGATCAGTTTCTAAAGTAAATAAAAGTTTTGGTGAAGAATCAAAAATAATGGGGGAAGATAAAGTTTTTTTTG
+
???DB?BD42:ADCEEAEA))1:CE<?*1::??*:BDEEECCE9/BBADD*=<8=B@AD.5=@CA=>).=.7??@@ABA2=888?<>5>>ABAA38;??3
@5ER
GTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACA
+
CCCFFFFFHHHHHJJJJJJJJIJJJCIJJJJJJIGGIJIJJJJIIJJIJIHIJJIJJJJJJJJJJJJHHHHHFFFFEDEDDDDDDDDDDDDDCDDDDCC
@5ES
GCCAAAGCTTTCCCCCTCCTCTGATGATTAAACAGGAACCCAGAGATTTTGCATATGACTCAGAAGGGCCTAGCGGCCACTCCATTTATATGAGGCAAGA
+
?@@FDDDFHHBFDHHGGFHEG9EG>HHB@FG49:D?BFFHGI;BD@GEH@>GHI>BCEECHG>CHG2;;CEEEF'9>:88,9<CCDC@B@D>:>C?BBBC
@5ET
CACACCATGATTTGAATATTGATCAATCACAGTGTAATGAAATGTACATAAATAGTTCTCAGAGAGTAGAATCAACTGTGATTCCTGAATCTACAATAATG
+
CCCFFFFFGHHHHJJJJJJJJIIJJJJIJJJJHHGIIJJJJIJJJIHJJJJJJJJIJJJJJJJJJJIJJJJIJIJJIJGGIIJJJJHHHGHHFDEFFFEEC
@5EU
CCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATAC
+
@C@FDFFFHGGHDIHIGHGIGBFIIBEHECHHGHIGFGIGEC<FHBGGIG@@AFEGG;EECEEFBCB@CE>>>@CCDCF@ACCCCCC>CBBBBB@BBBCCC
@5EV
CAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCATACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGC
+
=@;A4=AD<A::ADFHBGGIIGDBFBBEGIGCGGBDHF@FH@DGC9DFHIIIEFHIECAFHGIIGEH;=AC>EBDEE@BCC6;9;>CDEE@:CCDCCCC
@5EW
CCCGAATCATCCTGCTGGAGCTAATAGCGGTGGGGGCAGCCCAATCCTTCCACCCGCCAACCCGCCCGCACCCGAGCCAGCCCCCCTCCCCCGCCCTAAT
+
((0(((:@6>@1)9)2.9;<).)28).)(-((((((--'(6-6()..3==7)=;''','2(,'8800&&&&)80)&)&(+(686-8&&(+&)&&&&0(+(
@5EX
AATGCTACTCCCACCAAAAGCATAAAACGACCATCACCAGCTGAAAAGTCACATAATTCTTGGGAAAATTCAGATGATAGCCGTAATAAATTGTCGAAAAT
+
CCCFFFFFHHHHHJJIJJJJJJJJJJJJJJJJJJJJJJIJJJJIJJIIIIIJJJJJJJJJJJJJHHHHFFFFFEFEEEEDEEDDDDDEDDDEDCEDDDDDC
@5EY
GACACCTGTGTTGTCCCAGAAAAATTCGATGGAGACATCAAACAAGAGCCAGGAATGTATCGGGAAGGACCCACATACCAACGGCGAGGATCACTTCAGCT
+
=1:DDDDFHHAFHHGGGGIDIHIGIGGEGIE8*8CGGHB<DC<DF3BFDGG@GHA=FEH:;CEHHHFFF9?BDDDDCCCCCDD??B395>(989>@@>CAA
@5EZ
AGAAATACAGGAAAAGGAGACAATCATTGAAGAATTAAACACAAAAATAATAGAAGAAGAAAAGAAAACTCTTGAGCTAAAGGATAAATTAACAACTGCTG
+
CCCFFFFFHHHHHJJJJIJJJJJJJIJJJJJJJIJJJJIIIIJJJJJJIJIIJJJIJIJIJJJJJJJJJHHHHHHFFFFFFEEDEEEDEEDDDDDBDDDDD
@5F0
CCTGAACCCCCGGCACTCCGTGGATTTCAAACAGTCCAGGCTCTCCGAGGACGGGCTGCATAGGGAAGGGAAGCCCATCAACCTCTCTC
+
CCCFFFFFHHGGGIJJIIJJJJIJJJJJIJIJJJGHIJIJJIIGJJGIHHFFDCDDDDDDDCDDDDDDDDDDDDDDDDDDCDDDDDDDC
@5F1
CAAAGCTCTCCTGCTGCTGACCAAAGAGGACTTTCGCTATCGATCTCCTCATTCAGGTGATGTGCTCTATGAACTCCTTCAGCATATTCTGAAGCAGAGG
+
CCCFFFFFHHHHHJJJJJJJJJJJJIHIJHGIIJJJJJJJJJJJJJJJJJJIJIIIJCGGIIGHIIGJHHHHHHGFFFFFFEEEEDEEEEEEDDDDDDDD
@5F2
CTCCTGGTCTCTCAACAGGCAAAACGGGAGGAGGAGCGCAGCCCAGCTGCCCCACCACCTCTGCCTACCACCTCCTCTGGCAAGGCTGCAAAGAAACCCAC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJIJJIJJJIIJJJJIJJJJJHHHHHFFFDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDD
@5F3
TGAAAGCTGAGATTGTTTCTGCATCTGAATCCAGAAAGGAACTAGAATTAAAACATGAAGCAGAAGTTACAAATTACAAGATAAAACTTGAAATGTTAGA
+
@@@FFFFFHGHHGDHFDGGGIJGGHIGIEHICGGEEHGHEFAGEGJJIHGGHGGHGHFHIGIJ>FG=FHIIGGG@HEHHFFGHFFFFFFEEEEEE@@CC@
@5F4
ATAACTGTGTCCAGAGGACCCCCAGGCCATCCGTGGATAATGTGCACCATAACCCTCCCACCATTGAACTGTTGCACCGCTCCAGGTCACCTATCACGAC
+
CCCFFFFFGHHHHIJJJIIJJJJIIIIIIJJIJGIIIJJIIIBGIIJJJIIIIJIIIIIIHHFHFFFFFDECECEEEDBDDDDCDDACDDDDDDDDDDDD
@5F5
CCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTTATGGG
+
@CCFFFFFHHHHHJJJJJJHIJJJJJJJIJJJGJJJJJJJJJJJIJJJJJJJJJJIHHHIJHHHHHHEFDDDDDDDDDDDDDCDDDDEDDD3<@DDDDDDD
@5F6
CCACTGCATCATGCATCTCCAAACTCAACTCATACACCGAAACCTGACCGGGCCTTCCCAGCTCACCTCCCTCCATCGCAGCCCATACCAGATAGCAGCT
+
?;?DDD;;F>C:?FGACGIII?<<F@BAFF?91??CC?GGB?88D28B?A:;5;5777.;>;7BAA@>;?B3=;9::1558&88?B9@BA:8:4+4(+8(
@5F7
CCACCACTGACCATGGACACTGCGGTTAATTAAGATCTCCCCCAAGACGGCTACTTTACCTTTCTGGTGCTGGAATGTAGGATTGTTCCCCGAAGGCACCG
+
7((<23(98))24)))2;??<))((2(1<)):?;.))::=9-(00(()--;'8>6):>.)863==11...:=>53(-(-(-558;(((((('&)5&2(((&
@5F8
CGCTGGAGCGGGCGGAGCTGTGCGAGAGCCTCCTCACTTGGATCCAGACATTTAATGTGGATGCACCATGCCAGACCGTGGAAGATTTAACGAATGGGGTT
+
CCCFFFFFHHHHGJIIJIIJJJIJHHHFFFEEDEEDDDDDDDDDDDDDDDDDFEEDDBDDDCCBDDDDDDDDDDDDDDBBD?CCBDDDDEDDDDDDDDD5>
@5F9
CCCAGGCCATCCGTGGATAATGTGCACCATAACCCTCCCACCATTGAACTGTTGCACCGCTCCAGGTCACCTATCACGACAAATCACCGGCCTTCTCCTG
+
CCCFFFFFHHGHHJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJHHHFFDFFDEEEEEDDDDDDDDCDDDDDDDDDDDDDD4A
@5FA
CATAATTACATGCGGTAAATCTCATATTTTCTTCTGGACCTGGAGCGGCAATTCACTAACAAGAAAACAGGGAATTTTTGGGAAATATGAAAAGCCAAAAT
+
CCCFFFFFHHHHHJJHIJJJJJJJJJJJJJJJJJJJIJIJJJJIJJJJIJJJJJJJIJJHHHHHFFFFFEDDDDDDDDDDDDDDDDDEEEEDDDDDDDDDD
@5FB
CAAGCCCCCTGCAAGTGGCTGTGAAGACGCTGCCTGAAGTGTGCTCTGAACAGGACGAACTGGATTTCCTCATGGAAGCCCTGATCATCAGCAAATTCAAC
+
=+1<=7??<<??A>2ABCA<A2A+?7::A:4:A>>B=7=0=7?B?BABBA9AB=>(''-9;>@>6>((>..;5(-5;5====25;?:9=8;?;==8+:==?
@5FC
GAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACT
+
CCCFFDFDF8BFDCGD?EGGIIEHH<CHEGIDCGIHGHCHIEGCCBBBFDD>?BHICFGHIIG;AGEFEDCC6;CCDCCCCCCCCCCCC3>??ACCAB??B
@5FD
TCCTCCTTTGCCGACGATGCCAAGGGAAGGACGTCCTATGTACCAACGCCAGATGTCTGAGCCAAACATCCCCTTCCCACCACAAGGCTTTAAGCAGGAGT
+
CCCFFFFFHGHGHIJIJHGJJJJIIJIJJJJJIHIIGHJJFHIIJJJGIHHFFFFECDEEEDDDDDDDDDDDDDDDDDCDBABDDDDDDDDCDDDDDDDDC
@5FE
AGAGGACAAGTGCAAGCCTATGTCCTATGAGGAGAAGCGGCAGCTCAGCTTGGACATCAACAAGCTCCCCGGCGAGAAGCTGGGCCGCGTGGTGCACATC
+
;?@1B;?DFB<:<CF>BFGCE?F<<C<FF?HEFI@DCA?6:DFEIFII>D@F@;;@@@CA7=AB;37@;9;>@BBB<B3?B:@?8(55>>@<(8@BBBBB
@5FF
GGAAGAGGACAAGTGCAAGCCTATGTCCTATGAGGAGAAGCGGCAGCTCAGCTTGGACATCAACAAGCTCCCCGGCGAGAAGCTGGGCCGCGTGGTGCAC
+
@@@DFFDDDHGFHIIIJIIIJEEIIHIJJJJJFIJGIIIGGIIDHGECHIJFEIIJJGHHHHFFFFCDDCEDDDDBB7<BBDDDDDDDDDBD59>8?CCA
@5FG
ACTGAATATAAAATTGCAAGATACTAACTCTCAAAAGGAAAAACTCAAGGAAGAACTAGGACTAATTTTAGAAGAAAAGTGTGCTCTACAGAGACAGCTTG
+
@@@DDDDDDDHBCGGGBHIIGHI@HIIHEGHEGHIIDAGGGEHGGCCHICGIBGHE@FG;BBHGIIB@FHIHCEHEHFF.?BDDBCCCCCCCCCACCBCCC
@5FH
CTTTCCCCCTCCTCTGATGATTAAACAGGAACCCAGAGATTTTGCATATGACTCAGAAGTGCCTAGCTGCCACTCCATTTATATGAGGCAAGAAGGCTTCC
+
CCCFFFFFHHHHHJJJIJJJJJJJJJJJJJJJJJJJJJJJJJIJIJJJIIJJIJJJJJJCGIJJJJJJIJHHHHHFFFFFFFEFEEEEDDDDDDDDDDDDD
@5FI
CCAACGGCGAGGATCACTTCAGCTCTGGCAGTTTTTGGTAGCTCTTCTGGATGACCCTTCAAATTCTCATTTTATTGCCTGGACTGGTCGAGGCATGGAAT
+
CCCFFFFFHHHHHIJJJJJJIJJJJJJJJJJFHJJJJJDHIIGIIJJGHHEFHFFFFFEEEEEDDDDDEEEFEEDDDDDDDDBDDDDCCDBDDBDDDDCDD
@5FJ
GCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCC
+
@@@FFFFFHHHGFGGGIICHGFIJJIIJCHHJIJGHGJIJGIIJJIJJJJJJHIJIJIGIIJJJIJJIHDCHFFFDDEDDDDDDDDDDDDDDDBDDDDDD
@5FK
AGTACATTGCCATTGCCCCAAATGGAGCCTTACAGTTGGCAAGTCCAGGCACAGATGGAGTACAGGGACTTCAGACATTAACCATGACAAATTCAGGCAGT
+
@@BFFFFFGHHHHJJJIIJIJJJIHIIJJJJJJJGIJJIHJJJHJIJIJJJIJJJIJJJICHIJJJJ?GFHHHHHFFFFFFDEEEDECDDDDDCDDCDDDC
@5FL
CTCTCACCTCTCAGACAACTAAGACAGATGACCCCCAATTGAAAAGAGAAATAAGGTTAATGAAAAACAGAGAAGCTGCTCGAGAATGTCGCAGAAAGA
+
CCCFFFFFHHHHHJJJJJJJJJIJJJJJJJJJJJIJJJJJJJJJJJIJJJJJJJJJCGGIJJJJJIJHHHHHFFFFFEEEDDDDDDDDADDDDDDDDDD
@5FM
GGCCGGCCGTGGAAGGGGGACACGTGAATATGGCATTCTCTCAGTCCAACCCTCCTTCGGAGTTGCACAAGGTCCACGGATCCAGAAACAAG
+
@@@FFDFFGFHHHJGGGFGIEHJJFEGGIJJJJEHEGGIGFEFHHGFFFFFDDBDDDDDDDDDDDACCDDDDACCDCDDDDDDDCCDDDDD?
@5FN
CATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATAT
+
CCCFFFFFHHHFHJIIJJJJJJJFGHIIIJJJJIBDGIJIJIIJJJJJIJJJJIJJIIJJHIIJIJHHHHFFFDDDDDDDDDCDCDDDDDCDDDDDDDDDD
@5FO
CTTTGTCAGATGAGAAATGGGATGTTATTAACTGGAGGAGGGAAAGACAGAAAAATAATTCTGTGGGATCATGATCTGAATCCTGAAAGAGAAATAGAGGT
+
CCCFFFFFHHHHHIGIJJJJJIGIBFJGIIIIJJIFHIHIIJIJJJIJIIIIJJJJIJGGIJJGIJJEHHHFFFFFFFEDDDEEEDDDDCDDDDDDDDDDD
@5FP
AGAGCACACGCGTGATCCAGCTGATGCCCAGCCCCATCATGCACCCTCTGATCCTGAACCCCCGGCACTCCGTGGATTTCAAACAGTCCAGGCTCTCCG
+
@@<=BDFFFHHHAGIG<GHGGIG@CC?G;BF9BBG;?FH@?CFGHCFGAF@GIHIE>CCEA?BAB??@CCA?A?B8@CCCDCC>BCCCCCCCA<A9CC>
@5FQ
CCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGG
+
=?@BBBDDHDD?FH>GAACGEFI>AABBHEGGEHG@=?@:@?FGIE@DDH@B@CBFCEGHG@=CGCGHHC>=BCEED?>>>;>ABCBBB=??BBCBA>@CA
@5FR
GGGAGACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTT
+
@CCDFFFFHHHHHJJIJIIGIIJEHJFGIBFHIGECHGHIJIIJJHHHFFFDDCDDDCDDEEDDDDDDEDDDDDDDDCCCCDDDDBBBDDDDDCCDCDDDD
@5FS
TGAAGTTGTTTTGGCTGTGGAGTTTCACCCAACAGATGCAAATACCATAATTACATGCGGTAAATCTCATATTTTCTTCTGGACCTGGAGCGGCG
+
CCCDFDDFHFHHFIJJIDGIDGHHGIJJJIJIGHDHHIIIJIJJIJJJJJJIJJEIIJJJ@EHDEHEHHEFGFHFFFFDEEDEEECDD?BABDDD
@5FT
CCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTAT
+
@CCFFFDEHHHFHJIIHGIIGIJIJIDGIJIJIJFHHGIIIGGGAHIJIHHHHFFEFFBACEEE<>CCCDCABBDDDDDDDBBCDDEDBDDDBDBBDDCDD
@5FU
CTCCCCGGCAGTGCCCCCTCCCACCAAGGTTGTGGCCCCGCCCTCATCCAGCGACAGCAGCAGCGATAGCTCCTCGGACAGTGACAGTTCGACTGATGACT
+
CC@DFFDDHHHDHJIJIJFGIJIGIJIJIHJJDGEGHIFBHHFFFACCEEEDD?BDBBDBDDBBBD?BDCCCD>ABDBBB@@CDCDCCCCBDBBBDDDEDD
@5FV
GGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATC
+
@BCFDDFFHHHHHJJEHIJJIJJIJIJJJJJJJJJJJJJJJIJJJIJJJJJJJJJJJJJJJJJJJIHHHHHHFFFFFFEEEEEEDDDDDDDDDCDDDDDDD
@5FW
TGGCAGAGTGCCTCAAAAAGAAAAGAGATGAGAGACCACTCTTTCCCCAAATTCTCGCCTCTATTGAGCTGCTGGCCCGCTCATTGCCAAAAATTCACCGC
+
@7<DFFFDFFDHHEIIJIIJGJGIEHHHGHGGGIIJJJII>FGHDFGIGJIIJ@EGHJGAHGIFGCEHCEFCDBCAACDDBDDDCCCCDCDDDDDCCCCDB
@5FX
GTCCTATGTACCAACGCCAGATGTCTGAGCCAAACATCCCCTTCCCACCACAAGGCTTTAAGCAGGAGTACCACGACCCAGTGTATGAACACAACACCATG
+
@@@DFFFAFFDHD@DGHHIIJHHIHEBFCGGEIGIGJJGGHIJGIIEIICHIEAEGIJGIJGHAEHFD;@@CECCDBDDDDCC;BCCDED>CDDBBBDDDD
@5FY
CGACAAATCACCGGCCTTCTCCTGACCCCGAGCAGCGGCCCCTCCGGTCCCCCCTGGACAACATGAACCGCCGCCTCTCCCCGGCTGAGAGAGCTCAGGG
+
@@???D;DFABF?81C@FF9FA?CAD??F?<DGEGE'@FHF<=?B<=989?B8?6@0+2>82<34>(:8>@9;B999:33>@><<9588@:(+24>>AC<
@5FZ
ATGGACAGCAGATACTTGTGCCCAGCAATCAGGTGGTCGTACAAACTGCATCAGGAGATATGCAAACATATCAGATCCGAACTACACCTTCAGCTACTTCT
+
@@CFDFFDHHHHHJIIJJFEDHFHJIIJIIJGJCFGDBH@GGHIJJIIIHEHHGIIIDIGIIIIJJEHHHHHHFFEDDDCCBBDDDDDDDDDCDDCDDDDD
@5G0
GGACAATTTGATAACTAAGCAGAATCAATTAATTTTGGAAATTTCAAAGCTAAAAGATTTACAGCAGTCTCTTGTAAATTCAAAGTCAGAAGAAATGACTC
+
CCCFFFFFHHHHHJJJJJJJIIJJJJJJIJJJJJJJJJIJJJJJJJJJJJJJJJJIJIJJJJJJJIJIJIJJJJIGIIJJHHHHHEEFFFFFEEEEEEDDD
@5G1
GTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCC
+
?:=?DDDDFA?DF?AFBG;AHFI>FFE>EFEEEF<DBDFG9BGCFEBDBDFFEEFFFE@F@6C=>CEFB>B<9@@?555:;@@D@AAA8>B58??BBBBBB
@5G2
CCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTAT
+
CCCFFFFFHHHHHJJJJJJJJJJJJIJJJJJJJJIJJJJJJJJJJJJJJJJHHHFFFFFEEEEEDDDEDDDDDDDDDDDDDDDDDDEDDDDDDDDDDDDDD
@5G3
TATCAGACTAGCAGCGGACAGTACATTGCCATTGCCCCAAATGGAGCCTTACAGTTGGCAAGTCCAGGCACAGATGGAGTACAGGGACTTCAGACATTAAC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJIHIJJIJJJIJIIJJJJJHAEHGFFFFEEEEEEDDDDDDDEDDDDDDDDCDDDDDDDD
@5G4
CAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGAC
+
CCCFFFFFHHHHHJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJIJHHHHHHHFFFEEEDEEDDDDDDDDDDDDDDDDDDDDD
@5G5
ACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCC
+
@;?D?BADHHFBHIIA?FHHGIIGIGGIHGECHIGIIHIIIIGGIGHBDGGHIEHBCF@AGHIIIIEEGGFFFFFFECCCCECCCCBC@
@5G6
CGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTAT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJIJJJJJJJIJFJJIIIJJIJJHFFFFFFDDDDDDDBDDDDDDDDDDDDDCDDCC>CDDEDDDDDDDE
@5G7
CTGGACAGTTACCTTATTCAAACATCAACAACAGGGACCAGATAATTTTTATGGTGGGACGAGGATACCTGTCTCCAGATCTCAGTAAGGTACGGAGTAAC
+
@<@A?DDD=ABDDFHE9AEGIIICFH?CFHGGHIIIG7DGHGIIII@HGGGIIIHCGF2@G8BH<>BCDC>;@>ACCCC@CA:>@>>ACC::>8<<923>3
@5G8
ATTTGAAGCTGCCATTAAACAAAGAGATGGCATTATAACCCAGCTCACTGCTAATTTACAACAAGCAAGAAGAGAAAAGGATGAGACAATGAGAGAATTTT
+
CCCFFFFFHHHHHJJJJJJJJJJJJIJJJJIJJJJJJJJJJJJJJIIJJJJJJJJJJJIJJJJIJJJJJJJIHHHHHFFFFEEEECEDDDDDDDDDDDDDD
@5G9
CAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHJJJJJJJGIIIJJJJHHHHHFFFFFEDEDDDBDDDDDDDDDDDDEEDDDDDDDD
@5GA
ACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTGAGTTGCTAAGAGAGA
+
CCCFFFFFHHHHHJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJIIJJJJJGJJJJJJIIJJJIJHHHHHFFFDCBDDDDCB:AACCDDCDEDDDDDDD
@5GB
CGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCA
+
B@@DFDDFFHHFFIIJIJJIIGIIIJJJJIJJIGIIHIIHGGIIIIJEGIJIJIIHHGHHFDDDDDDDDDDDDCCDDCDDDCDDDDDDDDDDDDDDBDD
@5GC
CCAAAAGTTACCAAAACTGCAGACAAGCATAAAGATGTCATCATCAACCAAGAAGGAGAATATATTAAAATGTTTATGCGCGGTCGGCCAATTACCATGTT
+
CCCFFDFDHGHGHJJIJIIIJIIJJIIJJIIJIJIGGDGIJGIJGIJEIIIIIGGGGHEDGGHGIIJJGIIJDGHGHHHFFDD?@DDDBBACCDDDDDD@D
@5GD
CAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGG
+
BCCFFFFFHHHHGJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJIJJJHHHHFFFFFEEEEEEEEDDDDDDDDDDDDDDDDDDDDDD
@5GE
ATTCAGCTATGGAGAAAAGTGCCTGTACAATGTCAGTGCCTATGATCAGAAGCCACAAGTGGGAATGAGGCCCTCCAACCCCCCCACACCATCCAGCACGC
+
@@@FFFEFFFHHDDFFHIIAFFGGHBHCHFHHHGGGEHIIIIIIFFHHHHEHIIGHIIIDFGCEEFGIGIIGIGFHEFFFFACDD=B?BB?CCBCDCCBDD
@5GF
CAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGCCAACAAAGCAGCT
+
?;=D1@DDDCDDE9BEA,<<F+AFECE>*:E41:*1?98DDDE@D*B*09;BC7B(-5':'.6;@;73(.;5;=;?5((,,(5;5:(,:?8<129<A3<>
@5GG
CCAACTTCAGTGATTCAGAAATTTTTTCTTAAATAGCATTTATAAGTCCAGAGATGAAGCAAACAACAGTGGACTCATAAATGAAAGCTTTGAAGGTGA
+
=;>A1@AA4<<,2,27,7>A+++<<AAA<<AB<4::<:*:?A*000:*0*:9=9??*0*==)=>B2=28>B9)))).=>A@BB@);56(;>55;55;;;
@5GH
CTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTT
+
CCCFFFFFHGHHFIJJJJJJJJJJJIIJJIIIJJJJJIJJJJJJJJJJJIIJJJJIIIJFIHEFHHHFFFFFFDDDDDDDDDDDDDDDDDCC>CDDD><@B
@5GI
CCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGAC
+
CCCFFFFFHHHHHJJJJJIIIJJJJIIIIIIJJIJIJHHIGIIGIIGIJJJIGIJJHJJJGIJGJHGEFHFFFFFCEEDDDDDDDDDDDDEDEEEEEDDB
@5GJ
GGACACGTGAATATGGCATTCTCTCAGTCCAACCCTCCTTCGGAGTTGCACAAGGTCCACGGATCCAGAAACAAGCCCACCAGCTTGTGGAACCCAACGT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJGHIJJIJJJJGIIIJJJHHFFFFFFEEEDDDDDDDDDDDDDCBDDDDDDDDDDD?
@5GK
CACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCC
+
C@CFFFFFGDDHHGBHGIJJJIFIJIJIHIIIJIJGIGGHGHHFHCHGEHIIIHGHI@@EHHHHHFFFFFDEECECDDDB@<8ABACCDAAB8A@BAB@CD
@5GL
CCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTTATGGGCAGGAGT
+
@@CDDFFFGHHHDFGGEIGJIJJJJIJJJJFIIIIHIJJJJJIJJJJJJJJIIIGFIIJGIFHFFFFDDDDDD@BCDDDDEDDD599?DCCDDDDDDDDD9
@5GM
GGAACGTCACATCAACGAGGAGGACACAGTGCCTCTTTCTCACTTTGATGAGAGCATGGCCTACATGCCGGAAGGGGGCTGCTGCAACCCCCACCCCTAC
+
CCCFFFFFGHHHHJJJJJJJJJJIIJJJJHJJJJJJJJIIJIJJJJJIIJJHIJJJIJJJJJJHFHHHHFFDDDDDDDDDDDCDDDDDDDDDBDDDDDDD
@5GN
GCCAGATGTCTGAGCCAAACATCCCCTTCCCACCACAAGGCTTTAAGCAGGAGTACCACGACCCAGTGTATGAACACAACACCATGGTTGGCAGTGCGGCC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJIJJJHIHHIJIJJIJHHFFFFCDEEEEDCDDDDDDDDDDD>CDDDDDCCDDDDD
@5GO
AAATTAAAGTATATGAAATGGAACAAGATAAAAAAGTAGAAAACTCAAATAAAGAAGAAATACAGGAAAAGGAGACAATCATTGAAGAATTAAACACAAA
+
CCCFFFFFHFHHHJJJJJJJJJJJJJJJJJJJJJJJ?FHIIJJJJJIJJJJJIJJJJJJJJJJJJJIJJJJHHHHFFFFEEEEEEEDDDDDDDDCDDDDD
@5GP
AGCCTCTCCAGGGGCATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCGGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTC
+
1;(2-))29);9(((-..=6.<>>5)..<<?=?:>8.7)9;>7>?8:>?>??;)=9639;(8='-9;333((-:;:(75;<:;,((+8/24::4/(52(
@5GQ
CGGAGACTGCTTCCACTTCGGGCGGGGGAGCCCCGGACCGAATCGGCTCTCTAGGCCGTGGAGCTTGCCGTCCCACCTCCGTCCAAATCGACCTTTCCTTT
+
@@@DDFDDBFDHFIGFIHJGIGHIJID@BBDBBDDDDDDDDDDBDD8BBD@CACCCCB5;@?BDBD>BCB59>;@ABB??B<B>?CCA>@?>0<CDDCDCC
@5GR
GGTGGAGTCATGCTTATATGGAGCAAAACTACTGTAGAGCCCACACCTGGGAAAGGACCTAAAGGTGTATATCAAATCAGCAAACAAATCAAAGCTCATG
+
@@@FFFFEFHHHHJJJJJJJJIJJJJJJJJJJJIIJJJJJJJJJJIJJJJJIJJJJJJIIGIJJJ@DEEEHHFHHFFFFFFEEEEEDDDDDDDDDDDDDD
@5GS
AAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTCCTCCCCTTGGAGGGGCACAAACGATCAGTA
+
CC@FFFFFHHHHHJJIJJJJIJJIJJJJIIJJJJJJJJJJJGIGJJIIJIJIJJJIJJIIJIHGGEF?BDFFEDDEDDDDDDDDDDDDDDDDDDDDDDD
@5GT
ATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCC
+
@@BFFFDFHHGHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHHHFEFFFFEEEEEDDDDDDDDDDDDDDDDDDDDDDCEDDDCDDDDDD
@5GU
GTGATACTCAAGTAAGCTCTTTATTAGATGGAGTTGTGACTATGACAAGCAGGGGTGCTGAAGGATCAGTTTCTAAAGTAAATAAAAGTTTTGGTGAAGA
+
BB@FFFFFHHHHFHGIIJJJJIJJJJJIJJJFHGIHFGHJJJJJJJJJJIIJJJI@FHIJGJJIIJIHHHHHHHFFFFEFFEEEEEEECDEDDD9?ADDC
@5GV
GAAAAGCCAAAATTTGTGCAGTGTTTAGCATTCTTGGGGAATGGAGATGTTCTTACTGGAGACTCAGGTGGAGTCATGCTTATATGGAGCAAAACTACTGT
+
CCCFFFFFHHHHHJJJHHGIJHIJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJIJJJJJJJJJ@EIHHHHHFFFFFFECEEEDEDDDDDDDDDDDE
@5GW
CAAAAGGCCGGTGTTTGCGGACATCAGCAAAGACCTGGAGAAGATGATGGTTAAGAGGAGAGACTACTTGGACCTTGCGGCGTCCACTCCATCTGACTCCC
+
@@@DFDFFHFD<@@CEFGHGGIIGGIJJEGGG@GHGGCIEIJJFHIGIGGEFHFHFFDDFDDACCCCCDDCDCCDCDDD>@B@<BBDDDDCDDCCCDDCDD
@5GX
GTAAACTTAAAGCACTTAATGAAGAGCTTCATTTGCAAAGAATAAATCCAACTACAGTGAAAATGAAAAGTTCTGTCTTTGATGAAGACAAAACTTTTGT
+
@@@FDDDFHHHDHJGGGEHIJEHFAGGBGI<DHHHGGEEFGGHHIEHEIIGCEGIIJ8E?DFGHIGCIGGHHGGGCGHHIJHFHAHE?BCBEDECCCEDB
@5GY
CCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCC
+
@<@BDD3;DFDFFIGGHIEGGG@GAFHHIDIIGG:DFGAHCFH<BBD=FGH>DHGHICDGGE6==1?B@B>CC@C?A9>5>AC@CCBBBBBBB?CCCCCC?
@5GZ
CTGAAGAGGTGGCCCGACGTTGGGGCATTCAGAAAAACAGGCCAGCTATGAACTATGATAAACTTAGCCGTTCACTCCGCTATTACTATGAGAAAGGAATT
+
CCCFFDBDF<AFBHIEIIIEGCHEGGIIGIGEIGDGHHGHGEGHGDD=AEHGEHDFFD@DC@;@CEC;AB;BCCCCCCBBBB>C:@>4@C@CCCCCC?ACC
@5H0
ATCTACACCACGCAAAGTGATGTATGGTCTTTTGGAGTCCTGCTGTGGGAGATCGTGACCCTAGGGGGAAACCCCTATCCTGGGATTCCTCCTGAGCGGCT
+
?@@?1BD?FFFBFAE:<AEHDAH9FFFI@@F>BDE*:BBFFB*BDFB@<BFF3CD=2@;C>=D=7?<',9=BB7@B<A3(;@BBBBBB@BA>9>3?A7&00
@5H1
TAGGACTAATTTTAGAAGAAAAGTGTGCTCTACAGAGACAGCTTGAAGACCTTGTTGAAGAATTGAGCTTTTCAAGGGAACAGATTCAGAGAGCTAGAC
+
@@@FADDDBHHHHFIHGHIIGGHGDHHGIIIIIIFIGIIIIIIIIIIIIIIIIIHGGGGBGGIIIIIHIIIIIIIIGHHHFFFEFEEEEEECBBCCCCC
@5H2
CACCCAGCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCG
+
CCCFFFFFGHHHHJJJJIIJJJJJJJJJJJJJJJJJJJJJJIIJJJJJJIJJJJJJHIJJJJJJJJJHHHHFFFFEEEDCDDDDDDDDDDDDDDDDDDDDD
@5H3
CGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCA
+
B@@FFFFFBHHHFIIJIJIIJJJJIIJJJJIJIIJJIJJIHIJJJIJGJIJJJIJHHHGFDBDDDDDDBDDDDDD>CDEDDDDDDDDDDDDBDDDDDDD
@5H4
TACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCT
+
CCCFFFFFHHHHHJJJJJJJJIJJJJJJJJJJJJJIIJIJJJJJJI;EHGIIHHHHG?BEFFEEEEEEEDDDDDDDDDDDDDDDDDDDDDDBDDDDBBDDC
@5H5
AGGAAAAGAAAAAAAGAAAAGCACAAAAGGAAAGAGGAAGTGGAAGAGAATAAAAAAAGCAAAGCCAAGGAACCTCCTCCTAAAAAGACGAAGAAAAATA
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJIJJJJJBGIIJJJJJJIJJJHHFDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDD
@5H6
GGGAGGTGTATGAAGGCCAGGTGTCCGGAATGCCCAACGACCCAAGCCCCCTGCAAGTGGCTGTGAAGACGCTGCCTGAAGTGTGCTCTGAACAGGACGA
+
CCCFFFDDFHHGHJJJJJJJIHHHIJJJJJJJJJJJJJJIJJJJJJJJJJHHHHFFFCEEDDDADEEDDDDBBDDDDDDCD>C>CDDCDDCDDCDDDDDB
@5H7
CTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATG
+
CCCFFFFFHGHHHJJJJJJJJJJJJJJJJJJJJHJJJJJJJJJJJJJJJJHHHHFFFFFEEEEEDDEDDDDDDDDDDDDDDDDDDEDDDDDDDDDDDDDDD
@5H8
CCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGAC
+
@@CD?DBBADHDFHGHGHGGIEIIIIIIHIIIGBHIIICGDGEFGGBB>FGGIIDFGGGHBGE@CGEHDHFDDBBBA?@BBBBCAAC@CDCADCB>BBBBB
@5H9
GGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCT
+
CCCFFDBFDDHFFEHIIBGGGGHAHHIIDAHDHGHIEEIEHHGIIIIIDHIGGIEIICHGIIAHGA@DAEFHEHEDCDEDCECCEC?;ACCCACCDDDDC
@5HA
AACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJHIJJJJJJJJJJJJJJJJJJFGIJJJJJJJJJJJJJJHHHHHFFFFEEEEEEEDDDDDDDDDDDDDDDDDDD
@5HB
CATCACAATACTGGACCTCCCCCACGGGGGGAATCTACCCCAACCCCAACGTCCCCCGCCATCCTAACACCCACGTGCCTTCACACTTAGGCAGCTACTAC
+
@@@FFFFFHGHHHHIGHGGHIGGGGGIIJIDDDDCCDDCDDDD@BDDDBD@BBDDDD8@DDDDDCCCDCDBDDDDABBDCDDD>CCCDDDCDCD?CCACDC
@5HC
ATTCCTGATGGGCAGATTACAGTGGGACAAAGAATTGGATCTGGATCATTTGGAACAGTCTACAAGGGAAAGTGGCATGGTGATGGGGCAGTGAAAATGTT
+
??;ABA?+=DDDDDAEIDFEAE<<C=@ED@@EE>DFDD<??DDDE@DADDEIEIIIII<==@CD>CDD6A=C7?C;;>@@6>@A@(;?:??5>AAA>AA;>
@5HD
CCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGC
+
CCCFFDEFGHHHHIJJJJIJJGIIJJIIJJJJJJJJJJJJJJJIIJIJJIGIJIJJIJJJIJJJIHHHGHGGFFDFFFEDDDBBBDDDEDDDDEDEDCCD
@5HE
TGATGGCAGTGTGTTCACACTTTGTCAGATGAGAAATGGGATGTTATTAACTGGAGGAGGGAAAGACAGAAAAATAATTCTGTGGGATCATGATCTGAATC
+
CCCFFFFFHFHDFGHIJJIJJJJIJJJGEHHHIGIJIIGJHJGGHIIJIJIIIJGHICHIJIJJIIIHHHHHFFFFFEFDEDEDDDDDDDDCDDDEDDDDD
@5HF
TCTGTGGGCAGAAGGTTGCTTCCCATTGCTAGAAAGTGGTGATTCCACACTGGGGTCTTCCAAAGAAACCCTTCCACCCACATGCCAAGGCAATCTCCTT
+
@@@DD>DDHFADBG?G@EBHHIIIDFEH9BF@AFHI::3:?B?DFHBFHCH@HABAFCEHIIA@EHGCHEHEC?C@DCCC?=C>ACA:<??BBC@C>CAC
@5HG
CTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTT
+
@@@DFFEDHHHGHJIIJBEIIIIJI@GGGDHHIGGEIJFGIIIJGHIGHIIIIJIGGIHGDGHIHIJGFFHEFFFDDEC@CEDDDDDDDDDBBDDDDDDDD
@5HH
ATTGAATACTGCACCCAGGACCCGGATGTAATCAACACCGCTTTGCCGATAGAATATGGTCCACTTGTGGAAGAGGAAGAGAAAGTGCCTGTGAGGCCCA
+
???BDDBD<C<DDBE:EEC3E=FEECDD:9<DB9DD<BDDDADCA@CA;;AD>;?AD@D@>A6>A;>-;?AAA?=?9=<<=<AA>>:3(:A>>>>?>??8
@5HI
AGTGGGCATATGGTTATCGAGGAAAGGACTGTAGAGCTAATGTTTACCTTCTTCCGACCGGGGAAATAGTTTATTTCATTGCATCAGTAGTAGTACTATTT
+
B@?DDFFFHHHHHJJJJJJJJJJJIIJIIJIGIIJJJJGGIHIIJJJIJJJIGIJJIJJJHFDDDDDDDBCCCDDECDDEDDDEDDD>CDDEDDCDDDEEE
@5HJ
CAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAAC
+
@@@DFFFFDHHFGHIJIGIIGHIGGIJHIGGEGGIGEHJIEIHIIGIEEHGIIJJEGHIEGIJJHHFHEDBDCDEEEDDDEEDDDDBDDCDDDDDDDDDDD
@5HK
CGCGGCACTCCGTTCTCAGAGCTGTTCTACTCATGGCCAAGAGTTGAGTGAGGAATCTGATTAGTCCTCCGATTGAGGGGAACAGAGGAAAAGAGCCCCAT
+
-(-(((((2.)((2)5)))))22))26<993=6)<)(9)79((0<>1)).).(.6).)))).))..)))),'(((((,,'''(75((+(((+((+((()+(
@5HL
GGAGGAGAAGCAGGAGCTGTCGGGAAGATCAGAAGCCAGTCATGGATGACCAGCGCGACCTTATCTCCAACAATGAGCAACTGCCCATGCTGGGCCGGCGC
+
CCCFFFFFHHGHHJIJIJJHIJJJGIJJJIJHJJIJJJJGIJIJJHGHIIJJJIJIHEDDDDDDDDDDDDDDDCCDDDDDDDDDDDDDDDDDDDDDDDDDD
@5HM
AGTTCCTGGTGCTTCCGGCGGTACACTGCAGGTGGGTGGTCAGCTGCAACATGGCCTGGCAGCCTGGCCCTTGAAGCACTACACAGGCCACTTCCTACAGG
+
1==D;DD?F?DCFGGH@FFEEAGD988DA9C>8=CF'5=:.?@37?7>CCCC;A5;(;?29<BB?A??2<?A<4>@CC<:ACC(3<?0?82@>>AACCC@A
@5HN
CTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTT
+
CCCFFFFAFHHDHIGIIAEHHGGGIGHEIGGIIIGHEEHHIIGGBGEHGGCHHGIIIHIGIIGIGHGGHHHFFFFCECEEEECCCCCCCAABBBBBBBCAC
@5HO
AGCTTTTCAAGGGAACAGATTCAGAGAGCTAGACAGACAATAGCTGAACAAGAAAGTAAACTTAATGAAGCACATAAGTCCCTTAGTACAGTGGAAGATTT
+
CCCFFFFFHHHHGFIJJJJJJJJJJJIJJJJIIJJIJJJJIJJIIIIJJJIJIIJJFHIJIJJJJIIIIJJJGHHHHGEFFFFFFE@DEEE@CDDDD?CCD
@5HP
GAAACCTCAAGCTGAGAAAGTTGATGTGATTGCCGGCTCCTCCAAGATGAAGGGCTTCTCGTCCTCAGAGTCGGAGAGCTCCAGTGAGTCCAGCTCCTCTG
+
@C@FFDFFGHGGHJFHGBHGCCHGEHEHGIHIJJJFIGHIIIIGIJJJJJIGHIGGGIJGHCHEHFFEEC7;AB:>2?BDDDDD;@CCCCCCDACDCCCCC
@5HQ
CTAGAGGGAAAGCGAGAGGGAGACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGC
+
@CCFFFFFHHHHHJJJJJJJJJIJJJIJIHIJHIJJJJJJIIHEHFFFFDEDDDDDDDDDDDDDDDDDDDDDDDDDDEEDDDDCDDDDDDDDDDDDDDDD
@5HR
AACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTAC
+
?<?BD?DDB+:C:CC+<:<@+<8FFE>ECECDBD:?BDII>B?D??BBBCEI@C@=CA=CECC;A?D;AA@A;6;AADA>>;>-598=?3:5:9<<<<AAA
@5HS
GATGGCCGTGCGGAGGATATGGGTGGCTGATGGAGCTGGCTGAATGATGTGGGGATTGGGAAGGGTCCTTAGGCAATTTTACACTAGGGAAGGGGGGAGA
+
0(8(().-<(((--:(>))1)..07(((((0)<3()().()((..))))..),','(.(((-7,,((,,((,5(4(33((+6(+((++8((((&&)05&)
@5HT
CCTGTGACTCTCACCTCTCAGACAACTAAGACAGATGACCCCCAATTGAAAAGAGAAATAAGGTTAATGAAAAACAGAGAAGCTGCTCGAGAATGTCGC
+
CCCFFFFFGHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJIJJJJJJJIIJJJJHHHHHFFFFEEEDEDDDDDDDDDDDDDEDD
@5HU
CCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGAT
+
CCCFFFFFHHHHHJJJIIIJJGJHHIJJJJJJJJIJJJJJIJJGIJJJJJIJJIIJJJJIGGIJJJJJIHHHFFFFFDEDEECDDDDDDDDDDDDDDDDDC
@5HV
GAGCGCCCCCCCGCTGTCCCTCGACCACAGATTTCGCCGCCAGCTTCCTGAACCCTCTCACCCCTTTCCTCCTTTGCCCCCCCCCCCCAGGGAAGGACGTC
+
(--(:-5(5(0((-(0(9=8))'-5=/>?53>>9=0=;/9<//;0,(,(+::5<:(+++(5(8:(2(8:(8;(+3(+:+(0&)&)5:&&((&+8(((255:
@5HW
GAAAGACAAGAAGGAAAAGAAAAAAGAAAAGCACAAAAGGAAAGAGGAAGTGGAAGAGAATAAAAAAAGCAAAGCCAAGGAACCTCCTCCTAAAAAGACG
+
CCCFFFFFHHHHHJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJCHIHJIJHHHHHHFFFDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDD
@5HX
ACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACA
+
CCCFFFFFHHHHFIJJJIJJJJJJJHJJIIJJJJJJJJJIGIJJJJJJJJIIJHHFHFFFDCEEEDDDDDDDDDDDDDDDDDDDDDDDDDDDEDDDDDDD
@5HY
CTTCTCCCCAGCCCTCTTCACAACCTCTCCAAATACACAGACAAACTCCAGAAAGCAAGAATGCTACTCCCACCAAAAGCATAAAACGACCATCACCAGCT
+
@@CFFFFFHHHHFIIJJJIJEIJJJIIGIJJJJJJJJJJJJJJJIJIJJJJJJJJIIGFFGGIGIIIHHHHHFFFDDDEEDDDDDDDBDBDDDDDDDDDDD
@5HZ
GGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATG
+
?@@D;;D=DD7C?F@<3A@C:C@FHGH>>GEB>DFEHGI@FECFE@=B;=;FGEE/=<BDCCC@B9?@C(5>C:AA@@>;<>@B<?BBB?(<3>C:<(:A@
@5I0
CCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACAC
+
@@@DDBDDD?;CFA:C<:<FADHIEHGFGHEHBHIIIIIIGIIIICGGHECFE@FCFBB@FI<EAHFHCDDEEE@C>ACCACCCC;A>@:::;CCBCCCCC
@5I1
GAAAGCTGAGATTGTTTCTGCATCTGAATCCAGAAAGGAACTAGAATTAAAACATGAAGCAGAAGTTACAAATTACAAGAAAAAACTTGAAATGATAGAA
+
:=;AA;A=BA>>C72222<?C=+<<C7C=A=CCABB*@BB5:10000?7==00=*/?B4*=.8.8.>))>BBB;7.)..))7>>@@5=;5=?55(,,,:;
@5I2
GTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGCAACTACAGTTATCCCCAGGGACCTGGGAGCTACCCCATGC
+
8:?DDAD?CFF?<4A<EF4AA3;18?F;DG99B;88D@(=@F;CC;C;;=).?7?CA?)).;3;AC@;5>@(;;(,81'5<<?9<<<?B<:(<?88399
@5I3
GATAGATCCTGCATATTTTGATGAAAATTGGCTAAACAGAATCAAAACTGAAGTAGGAGATAATTGGAGGCTAAAGATAAGCAATTTAAAGAAAATTTTA
+
B@BDFDDBHFFFHJGGIJJJHJIFHHEHIIJJJJJJJEGEGGGHIIJJJIGHCB?DGAGDGGGGIGIGHIIIEIGIEEHHEEEFDFDCEECCACCCCDDD
@5I4
GAAATAACCAGTCATGAGCAGGGCTTCTCTGTGGAACTGGAAAGTGAAATTTCAACCACAGCAGATGACTGCAGTTCAGAGATGTGATTGTCATTTCTTT
+
C@@FDDFDFHFDDEIJIJFHCCIIIJGGG@DGHIFGGIHIHHCD?DBDEGHGGIJJJFJIIIGGICHAECHEAHEHFFEDDEDE;@CDECDEDDEDDDDC
@5I5
GTGATACTCAAGTAAGCTCTTTATTAGATGGAGTTGTGACCATGACAAGCAGGGGTGCTGAAGGATCAGTTTCTAAAGTAAATAAAAGTTTTGGTGAAGA
+
??@DD>DDCDFDC@GH94C9BHD<C:,<AAA38<?B4CBF4?<9C9?@?3BB;(?7';C=;@DD>DC>>7=?CB>?@@DDCCCDCCCC@C>@;=98CC:>
@5I6
ACGGGCTGCATAGGGAAGGGAAGCCCATCAACCTCTCTCATCGGGAAGACCTGGCTTACATGAACCACATCATGGTCTCTGTCTCCCCGCCTGAAGAGCAC
+
<@@DD6)@::?FFFB><BE8C>GCGIIGBEEIFADDFAGAGFFDF<;(6@D;=@>C@EFDBDDD;@CCC>A:;;A>>@@B:;>:::ABB>908?B@BB9><
@5I7
CGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCT
+
?@@DDD?DDDDDHBEBG=FGBH<C?FEHABG:::ECHEABGIHAF@ABHI@>6@8=;@CFHDCHAHHAEEEEE:149A?B??CCCC:@CCCCCCCB8?8?C
@5I8
CTAGGACTCCAAGACAGGCATTACTCACCCAGCGCCAAACCTACCTCCTCACAGAACGCCCGCATCCCGCTTTTTTGAAATTATTGCTGCGTCGTCCGGA
+
0(-(())..;4;)(2))((..3))6<)2:(-((((-(()0(00)./.(.))(.).).5'-5'33'3(,,3',(((&&++((+((+((((+&)0502(&&&
@5I9
CAACAAGCAAGAAGAGAAAAGGATGAGACAATGAGAGAATTTTTAGAGTTGACAGAACAGAGTCAAAAATTACAGATTCAATTTCAGCAATTACAGGCT
+
CCCFFFFFHHHHHIGIFHGIJIDIHIIJJJJJJJJIIIGIJIJJJJIJHIJJJJJIIIIGIIGGHJJJIJHHHHHFFFFFFFEEDEEEEDDDDDDDDDD
@5IA
GCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGC
+
@@@DDFFAFHHFBHI?CBGHDHB?FFGGIGE??FBC?G@GBFHBBG@BHBFFHGG;@GCHHC=AEHHEB@@DBC=B>CCCCCC@CADAC>A>>@CB<ACCC
@5IB
CCCGGCACTCCGTGGATTTCAAACAGTCCAGGCTCTCCGAGGACGGGCTGCATAGGGAAGGGAAGCCCATCAACCTCTCTCATCGGGAAGACCTGGCTTAC
+
CCCFFFFFHHHHHHJIJJJJJJJIJJHIJJIIJIJIJJIJIIJIIJIHFFFFCEEEEEDDDDDDDDDCDDDDDDDDDCDCDDEDDDDDDDDDDDDDDCDDD
@5IC
AAAAATTCACCGCAGTGCATCAGAACCCTCCTTGAATCGGGCTGGTTTCCAAACAGAGGATTTTAGTCTATATGCTTGTGCTTCTCCAAAAACACCCATCC
+
?;@AAD?D<FDDHIEA@>CDFGAFAE@CFEGGICB?>DGEGGGIG=CH=F=7@E>=).?6?ADCDCD@A@>BCDCDDA?A>5>>:CCCCC@9/<??><A(2
@5ID
GCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCT
+
CCCFFFFFHHGHHJJJJJJIIIJHIIIIIJJJIJJIJJJIGIHJJJJJJJGHIHHHFHEEEHFFFFEEEECDEDDDDDDDD<BBCDDDDD@BDDBBDDD
@5IE
CACAAAACGCCCGTCTTCGCCGGATCCGTCCTAATCTCAGCAGTCCTACTTCTCCTATCTGTCGCAGTCCTAGCTGGAGGGATGATTAAATAAAAAAATGT
+
00-(28(38@8@5-(21)((((((07<(7('-916:):=>7:0..)8:3=?8.6)8;8(...(((3;6(5(,(,(,((+2&)8-(((+(5/(+((55&(((
@5IF
AACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACT
+
CCCFFFFFHHHHHJJJJJJHHIJJJIIIJJIJJIJJJJJJJJJJJJIJJIGIIIJJJJJJJJJJJJJHEHHFFFFFEDEEEDEEDDDDDCDDDDDDDDD
@5IG
CCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGC
+
CCCFFFFFHHHHHJIJJJJJJJJHHJJJJJJJGIJJJJJJHIJJJJJJJJJJJJJJIIIJJJJIHHHHHGFFFFFDDDDDDDDDDDDDDDDDDDDDDDDDD
@5IH
GAAAATCAAGAAAGAACCCCACAGTCCATGTTCAGAAATCAGCTCTGCCTGCAGTCAAGAACAGCCCTTTAAATTCAGCTATGGAGAAAAGTGCCTGTAC
+
@@@DDDDDCFDFHGBBFDEH@GCF<CGG@G??CFDHEHGHHD9F?D?DB9DAFB)8B=FGEGHDGHIIGEHHHHG@BBDFDECCC2;=?C9-;>CCCCCC
@5II
GCCTGTCACTTCCTCCAGCTTCTTTGGAGCCGCATCACAATACTGGACCTCCCCCACGGGGGGAATCTACCCCAACCCCAACGTCCCCCGCCATCCTAAC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJHHFDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDD
@5IJ
GGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGC
+
@@@BDFFFHGHHHJJGIJJIIGGHJJJI@GEHJIGJJGIHIHIGHIJJI@HHHIJGIIIDEHEHEFFFFABCCCDECDDCDDDDDDD<A>?C@CCDDDDDD
@5IK
CATGCACCCTCTGATCCTGAACCCCCGGCACTCCGTGGATTTCAAACAGTCCAGGCTCTCCGAGGACGGGCTGCATAGGGAAGGGAAGCCCATCAACCTCT
+
@@CDDDFFHGHDHGIJGIIHIIJJGGGJGIIJJIJGGGHIJJJIJJIIIHIHFHHHDBDDFDDBDDDD?BB>BBDDDDDDCDDDBDB@DDDDCDDDCDDDA
@5IL
CTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAAC
+
@@CDFDDDHHAHHIGIIIIGDEHBHGGIIGIIDHIIIIIEIIECHIIIIIGIHI@@EDHEA;BA@BA::CCBC?BBBA<ABCCCCCCC@CCAC>8A9>CCC
@5IM
GTTCCTTGGCTTTGCTTTTTTTATTCTCTTCCACTTCCTCTTTCCTTTTGTGCTTTTCTTTTTTCTTTTCCTTCTTGTCTTTCTCCTTTTTCTTTGGTTTG
+
?:;DDBDDFFDFFIFIIFHFI<3CFFFEFIDFFFIFAF@DGIAEE@FFF>?FFFFEGIEGECFF>AEECB?>B;@:;>>>;A@ABA@BBBBBAB@@B9?<?
@5IN
GACCCCCAATTGAAAAGAGAAATAAGGTTAATGAAAAACAGAGAAGCTGCTCGAGAGTGTCGCAGAAAGAAGAAAGAATATGTGAAATGCCTGGAAAACCG
+
CCCFDFFFFHGFHIJEHBHGIHIJJIIBGIIGIIJIIJIJEGGGEIGFHGGGGIDCHCE@7BAEEEDDCEDEDDDCDDDDDD>;@DDDDDDDDBDDDDCDB
@5IO
CCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATG
+
CCCFFFFFHHHHHJIJJJJJJJJJJJJJJJJHIJJJIJJJJJJJJIEJIIIIIJJIIJJJJIIHHHFFFFFEEEEEEFDDDDDDDDDDDDDDDDCDDDDED
@5IP
CACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCT
+
?@@DDDD4DHHDHGEG>;?FGIIEBEFCHG@EGEGG8@DG<DGHD@A@;C@DCCE>EE@7@3;)>A?>A>;A:5@>;:;@C>C@A?9?B(4>ACCBBA?5A
@5IQ
CTTACACAACTGGGACTCCCAAAGCAACATCTTCTCACCAGGGCCTTGGAAGCACTTTGCCTAGAAGGGGAACCAGGAATGCCATAGTTCCGAGAGAAACT
+
@@?FFDDDAHHHHAFEEGGHDGGHIIFG>GHHGEGHIGDHGGHBFEEIBBFGCBBCFD@FEHD=C@=ABD:BB?AABB?CCCCCCCA;>@C@BB@B?A>CC
@5IR
GGAAATGAAAACACGGCATAAGGGAGAAATGGAGAATGCTTTAAGGTCATATTCAAATATTACAGTTAATGAAGATCAGATAAAGTTAATGAATGTGGCA
+
CCCFFFFFHHHHHJJIJJJJJJJJIJIJJJJJJJJJJJIJJJJJJJGHIJIJJJJJJJJJIJJJJIGIJJHHHEHHFFFFFFEEECEEEEDDDDCCDDDD
@5IS
CTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTAC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJIIJJJJJJJJJJJJJJJJHHHHHHFFFFFFDEDCEDDEDDDDFDDEDDDDDDD>CDDDDDDDDDDDD
@5IT
CGTTCGCAAGTGCAAGCCCCAGATGAATTACGACAAGCTGAGCCGGGCCCTGCGCTATTACTATAACAAGCGCATTCTGCACAAGACCAAGGGGAAACGGT
+
CCCFFFFFHHHHHIJJJJJJJJJJJJJJIJJJJJJJJJJIIIJJJJJJHHGFFDDDDDDEDDDDDDDDDDDDDDDDDEEDDDDDDDDDDDDDDDDDDDDDD
@5IU
AGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACT
+
@@@DD?D7DHDFBI@4B<FHGDEDHAEHGDGIEGGI>D@?;FGIBCAHHHIGIIIIFCH7?=>CDDC9A@=??B?A<3>CCCCCCBCCCA(4>@8??BBBB
@5IV
CGACATGTGAATATCCTACTCTTCATGGGCTATTCCACAAAGCCACAACTGGCTATTGTTACCCAGTGGTGTGAGGGCTCCAGCTTGTATCACCATCTCC
+
CCCFFFFDHFHHDIJIJJJJIIIGJEHGIJJIJJJJIJJJJGIIIIGIJJJJJJJIJIIIIJIJJICFGCECEHHHHFFFDEEEEDDBDDDDDDDDDDCD
@5IW
CCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCT
+
@B@FDFFFGHHGHGIJIHIEIIGGEGIIIGGHCGGIIIGHGBHEGGGIIIGJJGHGGGHHHHHHHFCEFFEEE?CDDBB@DDDDFCCCDCCCCCDDD?BDD
@5IX
CTTAAAACAGAATTGTTAGAAAAACAGATGAAGGAAAAAGAGAATGATCTTCAAGAAAAATTTGCACAACTTGAAGCAGAGAATAGCATTCTTAAAGATG
+
C@?FDFFFHHHHHIECFHIGIIJJIGGEHFHIIEHGEIJIBGHIEGF@FCFHEDFIGIJD=@GH@EEAGGCEHHFHCDCF;A6>AC;@CC@CCACCDCA@
@5IY
GCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACC
+
@BCFDAEFHHGHHIJIJJJIHGJJHHIIJJIJJIJJJJJJJJGJGGIJJIJJIJJJJJJJJJIJJJJJHHHGFFFFFFEEEEEDDDDDDCDDDDDDDDDD
@5IZ
ACAGAATGGCTGAATCACAAGAAGCTGAATTAGAGAGGCTGAGAACACAGCTTCTATTTAGTCACGAAGAAGAGCTTTCCAAACTGAAGGAAGATTTAGA
+
?@@DBD;D<CBFFD@BEBFHC@:?D?CFFE>HHG<FHIFCGCFGIE?G=FDDD)88BBCHC=8=);155AC7?6;?;;ACC>A?@A>;A;9:9,(5>>C:
@5J0
CACAAAAGGAAAGAGGAAGTGGAAGAGAATAAAAAAAGCAAAGCCAAGGAACCTCCTCCTAAAAAGACGAAGAAAAATAATAGCAGCAACAGCAATGTG
+
?@@DDDDDHBFDDCGGGDH:CGFDHIEDHGIGIIIIIBGGGBFFBFHGGGIIGEEEHHHECEDECC?>>@BBBCCCB@CC>CCCCCBBCBBB?CCCCAC
@5J1
CACCGCAGTGCATCAGAACCCTCCTTGAATCGGGCTGGTTTCCAAACAGAGGATTTTAGTCTATATGCTTGTGCTTCTCCAAAAACACCCATCCAGGCAGG
+
CCCFFFFFHHHHHJJJIJJJJJJJJJJI>GIGIJJIJJFIHHIIJJJJIJJJHIIJIHHEHHHHFFDFEFF@CEEEEDCDDDDDDBDDDDDCCDACD@<BD
@5J2
ATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGT
+
@@@DDFEFHHHHHIGJJHJJJJIHIIIJJJIIGGGHGHGIIGGGIIIIJIJGGGEGHGGJICHEFHHHFDFFFFCCEACDDDDDD?CDDBDDDD9?BDDD+
@5J3
CAACACCATGGTTGGCAGTGCGGCCAGCCAAAGCTTTCCCCCTCCTCTGATGATTAAACAGGAACCCAGAGATTTTGCATATGACTCAGAAGTGCCTAGCT
+
CCCFFFFFHHHDFIIIJIFHIIJIJJIIJJJEHHEGCIIIJJBHICHDGHIIGHHHHHHFFFFDACDBBAB?CDDCCCDDACDAC;>>ACDD4@ACCC9CC
@5J4
CCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACC
+
CCCFFFFFHHHGHJJJJJJJIJJHHIJJJJJJJIIJJJJJJJJJJJJIJJIHJGJIIJJJJJIJJJJJHHHHHFFFFFFEEEDDDDDDDDDDDDDDDDD
@5J5
CACAAATTCGAGCATCACCTTCTCCCCAGCCCTCTTCACAACCTCTCCAAATACACAGACAAACTCCAGAAAGCAAGAATGCTACTCCCACCAAAAGCAT
+
CCCFFFFFHHHHGJJIIHGIIGIJJJJJJJJJJJJJJIJIJGGGJIJIJJJIJJJIJIJJJJJJGHHHGHFFFFFECEEEDDDDDDDDDDDDDDDDDDDD
@5J6
CCTAGAGGGAAAGCGAGAGGGAGACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGC
+
CCCFFFFFHHHHHJJHIHIJJIJIJJJJJJGIJIIIJJJJJGHHEEFBEEDBDDDDDDDCDDDDBDDDDDDDDDDDDDEDDDDDDDEDDDDDDDDDDDDDC
@5J7
TGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTT
+
=8?DDDDDBAAA?GHFGEEGGGFAGHEHIIGIG?GIDFE<?09DAFBFBF<FHFG;FHIIEHGG3=@ECFEHE;;;B>@ACABBB283;9C@:@4@ACC::
@5J8
AACATAAATACTGACCTCACCTGGAGCTTTCCCTTATGAATTTGGATACAAGTTGGCGATTTTCGGTCGAGAAAGACAGACGGCGGGCCCCGCTTCTGAGG
+
(0(2().)..=).==.2)33()).32).)).)9)))):)))))0):03)<)))))))0--:9))9'-5/5,('.6(4(((,,'35&)))0&&&&&)(3+((
@5J9
AAGCCCTCGAGCAGTTATTCCCATGTCCTGTATAACCAATGGAAGTGGTGCAAACAGAAAACCAAGTCATACCAGTGCTGTCTCAATTGCAGGAAAAGAA
+
CCCFFFFFHHHHHJIJJJJJJJJJJJJJJJIJJJJJJJJJJJIJJDGIGGIJJJJJJJJJJJJJJJJHHHHHHFFFFFFDEEEEEEDEDDDDDBDDDDDD
@5JA
TGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGG
+
CCCFFFFFHHHHHJJJJJJJIIIJJGGIIJJJIJJJJIJJJIJJIIIJ@@GHIJHHHEFFFDDEDEDDDDDDDDDDDCBCD>@CCCDCDDEDDDDDDDCDD
@5JB
GCCCTTTTCTCCATGGCCTTTCCAGATAATCAGCGTCCACTGCTGAAGACAGACATGGAACGTCACATCAACGAGGAGGACACAGTGCCTCTTTCTCACTT
+
@@@DDDDAFD?FHIIIHIICGBHEH@>AHEEFHDGE?0CBDG<BFHEGDFEEEHGHIGGIGIGIIIGIHFFADBDAAAB=2;<AA@@:ACACCCCCCDCCC
@5JC
GCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGT
+
@@@FDDDFGFDHHIJJIIGGGEHJIII>AEGHGIHIIIIIJGHEGIIIIGHGHIIAEGGIGIHE?EEFHFFDECECE;;;>CBBD@BBD?A5<BDCD?CCA
@5JD
CTCTTCTGGATGACCCTTCAAATTCTCATTTTATTGCCTGGACTGGTCGAGGCATGGAATTTAAACTGATTGAGCCTGAAGAGGTGGCCCGACGTTGGGGC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJGHJIJIJJJJJJJJJJIJHGHHGHFFFFFEEEEEDCBDDDDD@BBDDDDDDD
@5JE
CTTCAAATCAATGAACTTCAAAAAGAAATTGAAATACTCAGACAAGAAGAAAAAGAAAAGGGTACACTTGAACAAGAAGTTCAAGAATTACAACTTAAAAC
+
CCCFFFFFHHHHHJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJIJJIJJJJJJJJJJJJCGHIJJJJHHHHHFFFFFEEEEEEEDDDDDDDDDDDDDC
@5JF
ATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGC
+
CCCFFFFFHHHGHJJJJJJJJJJJIJJJJJJJIIJJJJJJJJJJJJIJJIHIIJIIJJJJIJJJJJJJHHEHFFFFFFEDEEDDDCDCDDDDBDDDDDDD
@5JG
GGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCAT
+
CCCFFFFFHHHHHJJJJJJJJJJJJGHJJJJIJJJJDHIJJJIJJJJJJIJJJJJJJJJJJJJJJJJHHHHFFFDDDCDDDDDDDDDEDDDDDDDDDDDDD
@5JH
CCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTAT
+
CCCFFFFFHGHGHJJJJJIJJJIJJJJIIIJJJGIJJJJJJIJJIIJIJGIHHGFFFFFEEDDDCDDEDDDDDDDDDDDDDDDCDDEDDDCDDDDDCDCDD
@5JI
CCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGT
+
C@@FDDDDHGHHFIJJJJIIFFHIGIJIIJIJIEGDEGGHGHEGIEHJJIGIHACHFEFDFFDDECCCEDDDDCCDCDDBD2?BDC>CBB@?CCDDDDDDC
@5JJ
CGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCA
+
@@@FF@DDHHFHHIBHIIJIDCHHIHGHJIIJJIIIJJIHHGIIJJG@FHGIEGIHHHHCDCD?BDB=??AB?C@>@CDDDDDDDBDBDDDDDDB@BDD
@5JK
CTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTT
+
CC@FDFFFHHHGHJIJIJJIJIGHIFHHJIGIJGIIJJIJJJDIJGIIJJIIIJIIIGIJJHEHHHFFFFDDFCDDDBABDDDDBDDDCCDCD@CBB3<5?
@5JL
GTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCC
+
@@@FDDEEHHDFFIJJGICCFHCGCHCBHGEIFIJJIHIIIGHIGDHIIJIIJI@HGHHHHHHHGFFB;?ACCDDDDDCDACDDEDCCDCDDCCCCCCDBD
@5JM
GTGCTGCTATGGGAAATCATTTCTCTCGGATATATGCCATACCCCAGCAAAAGCAACCACGAAGTTCTGGAGTTTGTCACCAGTGGAGGCCCGATGGACCC
+
;<<8?89;)).)())2)).).;))@).((2-8)8)):)33<:<><=11)9<19=:>3>=(3338591).8)96)(.(((.((,-57<(,(5()0)&0+48:
@5JN
GAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACC
+
=?+4=+:;8?D1<CEEA)8E<ECE<DDD9D*?0?<908B*03*9B0@'''.=6'-6;?3;;>3(6>;A>>;/8,8<(22(2(+9A:>>A:44(++43><>
@5JO
TTTTGGATCACTTACCATCTGTAACAAAGGAATCATCACTTAGAGCAACTCAACCAAGTGAAAATGATAAACTTCAGAAAGAACTCAATGTACTTAAATC
+
CCCFFFFFHHHHHJJJJJJJJIIJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJHIJJJHGIJJIJJJJJJJJJJJHHHHHHFFFFFEEEDEEEFFEDDED
@5JP
CCTGGCTCATCCCAGCAGAACAGAAGGCTGTATGTTTGAAAAGGGCCCCAGGCAGTTTTATGATGACACCTGTGTTGTCCCAGAAAAATTCGATGGAGAC
+
CCCFFFFFHHHHGJJJJJIJJJJJJJJJIIHIJJIIJJIJIJJJJJJJJJJJJIJHJJJIJJJJJHHHHHFFDEFEDEEEDDDDDDDDDDDDDDDDDDDD
@5JQ
CTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTT
+
@@CFDFFFHGDBFHGDGIIIHIHGGIIGGIIIJBHGIIDGGGHGIHIGIJJGIJIGIGHIIHHHEEEEDFDDDDABB?B<?ABDBDDDDDDDCCDBB9<58
@5JR
TGACCCTTCAAATTCTCATTTTATTGCCTGGACTGGTCGAGGCATGGAATTTAAACTGATTGAGCCTGAAGAGGTGGCCCGACGTTGGGGCATTCAGAAA
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJIIJIJJJJJJJJJJJJIJJJJJIJJJJJJJJHHHHHFFBDDEEDDDDDDDDDDDDDDDDEDDDD
@5JS
CAAAGCTTCGTACAAGGATCTGGCCTACTCTGAGGAGCCACCTAAGACCAAACTTAAGGGGAAGGCCGGCACTGCAGAAACTGGAGGGGCGGATAGATAAC
+
((7((22).())(2@)(.@)6).)2).)))2.))()((-.)(()0.9)09>:>).)./)('-'((((,3'',((,,(((,,32+(((&))5))&0(((+++
@5JT
GTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCACCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACA
+
;@@BDDDDFHHHFA;B;<AFDFF<?FH><*::?:DFGIGED:?FHGIEHI*9==B@FHFI=F;=;@==7AH>B@<=B96;?55;299,55@C3,,>C9>
@5JU
CAAAAGCCATGAAGAGATTAATGGCAGAGTGCCTCAAAAAGAAAAGAGATGAGAGACCACTCTTTCCCCAAATTCTCGCCTCTATTGAGCTGCTGGCCCGC
+
@@@FDFEDHHHHHFHHEGGHJBHIIIJGJ:EDHHIEIIGIIIHIJIJFFHGGHHJGGGHICHIIIJJJEFHEFFEFFFCDDDCCDDDCDCDDCCCDBDDDD
@5JV
CGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCT
+
@@@DDFFFHHHHHIIJJJJJIJEHIGIIIJJEEHHGIJIGIGIJGGHGHHJJJIIIIJJJJJIJIIECHHHHFFFFDDBDDDDDDDDDCDDDDDDDBDDDD
@5JW
ATTGTTCTGTATGAATTGATGACTGGACAGTTACCTTATTCAAACATCAACAACAGGGACCAGATAATTTTTATGGTGGGACGAGGATACCTGTCTCC
+
@CCFDFFFHHHHHJJJJJJJJJJJJJJJJJHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJIIJHEHHFDFDDDDDDDDDDDCCDDD
@5JX
GGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATAC
+
CCCFFFFDHFFHFIHGIIHGEHGHIGGHIGGGHIGIGGIEIGIGGGIIGIGICCGGIHGGEBHEEFFEEEEEDECDDDCDDDC?9<?CBDCDDDD>CCCED
@5JY
TGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTAC
+
?@=D?DDDH?@FHGGEHGFHADFEGIGEIH??BGD@AFHBBFGBFHG=CFHGHEIIIGHII=E=>DCB=CCEECCA>CCCCC??=?B<28::?CCACCC:
@5JZ
CAAATTCGAGCATCACCTTCTCCCCAGCCCTCTTCACAACCTCTCCAAATACACAGACAAACTCCAGAAAGCAAGAATGCTACTCCCACCAAAAGCATAA
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJHHHHHFFFFFEEEEEEDDDDDDDDDDDDDDDDDDD
@5K0
CTCGAGAGTGTCGTAGAAAGAAGAAAGAATATGTGAAATGTTTAGAAAACAGAGTGGCAGTGCTTGAAAATCAAAACAAGACATTGATTGAGGAGCTAAA
+
@;?DFDADFFCFDCGHDEEHGGIIIIEGFDCHIC?CFFIGBFGHFGECGHGC;?FAFGFH7C7=@;@CGH>AHHFDDEFA@36;@;(5>53><5895>@C
@5K1
CCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTTATGGG
+
CCCFFFFFHHHHHIJJJJJIJJJJJJJJJJJJJJJJJJJJIIJJJJJJJJJJJJJJIJGHJHHHHHHFFDDDDDDDDDDDDDDDDDDEDDD9<<BDDDDDD
@5K2
CAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJIJJJJIJJJJJIJJJJJJJJJJJJJJJJIJJHHHHFHFEFFEEDDDDDDDDDDDEDEDDCDDDDDDCCDDDDD
@5K3
CTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGT
+
CCCFFFFFHHHHHJJJJJJJIJJJJJJJJJJJJJHJJJJJJJJJIJJJJJJJJJJJJIJJJIJJJIJHHHHHHFFFFDEDBDBBDDDDDDDDDDDDDDCD:
@5K4
CTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATG
+
CCCFFFFFGHHGGIJGIJGIJJIJGGIFIIJJJGIJJJJJIJJJIJIJJJHHEHFFFFFEECEEDDEDDDDDDDDDDBDDDDDDDDDDDDDDDDDCCDDDD
@5K5
CAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATG
+
CCCFFFFFHHHHHJHIJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJHHHHHFFFFFEEEEEEEDDDDDDDDDDDDDDDEEED
@5K6
CACCTGGGAAAGGACCTAAAGGGGTATATCAAATCAGCAAACAAATCAAAGCTCATGATGGCAGGGTGTTCACAGTTTGTCAGATGAGAAATGGGATGTT
+
;=;<?A81+??7=A7CACACAB+?):?7*@?AAB7?BBBAB>ABBB>9=AB)).=)9>AAA>AA'4=A9;)7;.(.6>>53;;==?3=;?:99>=::2+8
@5K7
CACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTG
+
CCCFFFFFHHHHHIJIIJJJJJJJJJJIJJJJJJIJJJJIJJJJIJJJJJIJJJJJJJJJJJIJJHHHHFFFFFFEEEEEEDEDDDDDDDBDDDDDDDDDC
@5K8
GTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTAC
+
@@@FFFFFBHHHHJJGBHIIFIGJJJIJJJJFICDHGIJGGIGGGIGIJHHGIJFHGGGJGIIHIHHGHGGDEFFEEE@@B@CDDDDDDCDABDAACBDDD
@5K9
TATCCTACTCTTCATGGGCTATTCCACAAAGCCACAACTGGCTATTGTTACCCAGTGGTGTGAGGGCTCCAGCTTGTATCACCATCTCCATATCATTG
+
CCCFFFFFHHGGHGHHBHGHIJJIGIHHIJIJJIIJJJJJJJJGGIGIJJJJJIGDGEFHJIJIGGGGHHFHHFFDE@CE@A@CDCCDDCDDDDCCDC
@5KA
AAAGAATCTCCTGTCTCTGCTGGAAATGATGCCTATGTTGACCTTGATCGTCAGCTGAAGAAAACTACAGAGGAACTAAATGAAGCTTTGTCAGCAAAGG
+
CCCFFFFFHHHGGHHIJIIJJIGJJJGHJEGJJGIJJGHGDHJIJIIGIIIIIGIHGIGIJIJJIGGJJFIE=EHHEHHFFFFFFEEEEA@CDDCDDD?C
@5KB
GATTGAAGAGCTAAACAGAGAGCTGGAAGAAATGAGGGTTACCTATGGGACTGAAGGACTGCAGCAGTTACAAGAATTTGAAGCTGCCATTAAACAAAG
+
CCCFFFFFHHHHHJJIJJIJJJJJJJHJJJIJIJJJJJIJJJJIIJJJJIIJJJJIJIIJJJJJJJJHHHHHGEFFFFFEDEEEEDDDDDDDDDCDDDD
@5KC
GGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACAC
+
=+:BDDDDDDDD:CEED?EBDFEII@CEE99EEE<D>DADCDDDDDI;DDDEDDIBBACDEIICECDDCCDCC@@@DD@@AAA?A>?A>>ADA>>AAAA?
@5KD
CGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTT
+
CCCFFFFFHHHHHJJJJJJJJJJJIJJJJJJJJJJJHIJJJJJIJJJJJJJJJJJJJJJHHHHFFFFFEEDEEDDDDDDDDDDDD?BDDDDDDDDD>CDDD
@5KE
TATGCAAACATATCAGATCCGAACTACACCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATGACATCTCCTGTGACTCTCACCTCTCAGACAACTA
+
@CCFFFFABFHHBGGIBGGIIGIIGIIIIIIIIGIIIIIIIIIIIIIIDHIIIIIIFFHFHEHGGHIIGIIGFGHFHFFCFFFEECCCCCCACCCCCC
@5KF
CAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCC
+
@@@FFFFFHHHHHJIIIEIJIJIIJJJIJJIJGIJJI<DDHGHIFFHIEGGGG=CEDDCDHFFFEHFDDEFEEEDDB=BBDCDDDD?CDADDDDDCDDDD
@5KG
CACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCA
+
@?<DDDBB=DFHHGE@FGEIGAABDHGFII=FH@GFG<:CGG>FEH>EG@BDE6A<87@@EB;CAEBD@DE;@:@,=A??BB3,9AA@CCAC@@C@CCC<
@5KH
CAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTG
+
CCCFFFFFHHHGHJJJJJJJJJJJJJJIJJJJIJJJJJJJIJGHJIJIJJGJJHHHHFFFFEEEEEEDDDDDDDDCDDDEDDDDDDCDDDDDDDD>CCDCD
@5KI
CGAGAACTGGAGACAGAAAGAGAAAATCAGTTCGGGGTTGCATTGTGGATGCAAATCTGAGCATTATGAACTTGGTTATTGTAAAAAAAGGAAAGAAGGAT
+
00(2-(2:@<>?)(92;@<7>?<>47)))9@8>9(((-8((098)8)7=>;(<3).).;.;3)).)8..:=39(6((.3;=;7;=(;8:528(+(85(65/
@5KJ
CCTACACCTCAGCAGTTACAAGCCTTCAAAAATGAAGTAGGAGTACTCAGGAAAACACGACATGTGAATATCCTACTCTTCATGGGCTATTCCACAAAGCC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJHIJJJJJJJJJJJJJJIJJJJIJHHHHHHHFFFFFFEEEEEEDDDDDDEEEDDDDDDD
@5KK
GCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATAC
+
CCCFFFFFHHHHHIIIJIJJIIIIJJJJJEHGGIJJJIIGIIGGEIJIJJJJIIJJIJGGHHGFFFFDEEEEDDDDDDBBDDDDDDDDD:?@CCACDCDDC
@5KL
CATGAGGGTTCAGCTGGAATATACGTAGAAACACGAGAATTGTCCACCCCGGGAAGAGTAGTGATCGATATCCCCACCGGCGACAAAGTATTTGGCTGATT
+
0;--())2:(394)26)9))))338:)(8391?(8-((0:3)).0))0(7-'''5((().)..6=((,37'((,(7'',5&0&&))82(((+(((((+((+
@5KM
CTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATG
+
@@<?D;DDF:CDFHDIICF8GHEHHIG=BGCEE9B9BFGHEHIIIIGGAEEHFC;CD;>C>@;;>>CC@??A<<AB@?BBB<ACCCCBBCBB<<A?CCCCC
@5KN
AGAATGATGAACTGACCACTTTGGCAGATGAAGCTCAGTCTCTGAAAGATGAGATCGACGTGCTGAGACATTCTTCTGATAAAGTATCTAAACTAGAAGGT
+
CCCFFFFFHHHHHJJJIJJJJJJJIJJJIJIIIJJIJJGIJJJJJJJJIGIJIJJJJIIJGHIJJIJHGHHHHFFFFFFDCEEECEEEEFDDCDDDDDDDC
@5KO
AGTTGGCAAGTCCAGGCACAGATGGAGTACAGGGACTTCAGACATTAACCATGACAAATTCAGGCAGTACTCAGCAAGGTACAACTATTCTTCAGTATGC
+
@C@FFFFFHHHHHJJIJJIIJIJJJJIEFHJJJJHIJJJJJJJJJJJJJJIJJJEIJIJJIJJJJJJHIJJHGHHHHDECEFEEEEEEEEEEDEDCDFED
@5KP
CCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACA
+
@@CADF?DHHFBFBGGHIIFGIIGGEHGBFD@BDFEEDGHGIGGIIIGGIHICGFFHIDHIGIIFFEEDE@EDDDCDCCDDD<CBDDDA>CCDC(>A@@C
@5KQ
CCCATATGCCTGGGTGGTCTGTGCATATCCTTGAGTGGGCTGGGCGGTGTAAGCACTGTAGCCCTGCTGCGCTGCAGCTTGGCTATAGGTACTGTAATCCG
+
???DD>;BDDDD;E+2)1<C?AAFFE><411:?*C:9):1B?:?D?6'--.773?7;;(;..6;?=555;=838;A9A>:3894(+>:A(:>>3+:::(:5
@5KR
CCTACACCTCAGCAGTTACAAGCCTTCAAAAATGAAGTAGGAGTACTCAGGAAAACACGACATGTGAATATCCTACTCTTCATGGGCTATTCCACAAAGCC
+
CCCFFFFFHHHHHIJHIJJJJIJJJJJJJJJIJJJJJGIJJJJGIJJJJJJJJJIJJJJJJJJJHIHHHHHHHFFFFFFEEEEEEDDDDDDEEFDDDDDDD
@5KS
CTGAAGCAGGTCAACCACCCACATGTCATCAAATTGTATGGGGCCTGCAGCCAGGATGGCCCGCTCCTCCTCATCGTGGAGTACGCCAAATACGGCTCCCT
+
1=+=DDD?D:2A<<EEI>BC:;FBE@DEE9EEDECD9:DDBDDID;DDDDEBCDC());A@ADDD@@A@>;>5>A3=52(,:>A>>9???A>4<?>5;889
@5KT
GAAAAATTCGATGGAGACATCAAACAAGAGCCAGGAATGTATCGGGAAGGACCCACATACCAACGGCGAGGATCACTTCAGCTCTGGCAGTTTTTGGTAGC
+
@<@DFD?ADFDDFGBGHIGHFHCFGIIIIHEHIIAGIBG?BGHGB@G@@BHI2@DECEEEHHGD=9<BB85;?9<(:@CA33::4>C>?<3@:ABCC8@CA
@5KU
CGCCAGTGTCCCCACTGCATCATGCATCTCCAAACTCAACTCATACACCGAAACCTGACCGGGCCTTCCCAGCTCACCTCCCTCCATCGCAGTCCATACC
+
@@@FFFFFHHHHHIJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJIJJJJJJJHFFDDEDDDCDDDDDDDDDDDDDDDDDDDBD?CDDEDDD
@5KV
CACCTCTGCCTACCACCTCCTCTGGCAAGGCTGCAAAGAAACCCACAGCTGCAGAGATCTCTGTTCGAGTCCCTAGAGGGCCGGCCGTGGAAGGGGGAC
+
???D;D:=D:A?ABBAEIADI;E?<EDCB=3?))?CDEA3BD;@1B6?CBCDA9CADDCCE@;@CC5(.;@DD@;@AA;>????;>?99>8>>??>?.;
@5KW
CGATAATCCTATTTATTACCTCAGAAGTTTTTTTCTTCGCAGGATTTTTCTGAGCCTTTTACCACTCCAGCCTAGCCCCTACCCCCCAATTAGGAGGGCAC
+
1114ABDEBF>FDGH?FFGCCHDGEE@BHFECGGCEHJG0@D@GGEI9CEGFFCFHGGGGGG@>;AC9CDD(;;@:ACDDBBBBABBDD?:A:@C9.&&+8
@5KX
TTTAAAGCAAGAGAAAGAACAAGTTTCATTGAGATGTAGAGAGCTAGAAATCATTATTAACCACAACAGGGCAGAAAATGTACAGTCATGTGATACTCA
+
CCCFFFFFHHHHHJIJJJJJJJJHHJJIJJJGIIJJFIIJJIJJJJIJJJJJJJJJJJJJJJJJJJJJJJIJHHHHFFFFCEEEECCEEDCCDEEDDDD
@5KY
CCTACCATGCCCACCAGCAGAAGGTGAACTTTGTCCCTCCCCATCCATCCTCCATGCCTGTCACTTCCTCCAGCTTCTTTGGAGCCGCATCACAATACTGG
+
@@@FFFFFHHHHHJIJJIGIJJIJDFEGHJGHJGIJJJIIJJIGGIGCDGHGIFH@FHHDFHFGCGIIIHHGFDFFFFFFEE3;ABDBBDDCDDDDDDCDD
@5KZ
AGGAAGTCATCTTCATCCTCAGAAGACAGGAATCGAATGAAAACACTTGGTAGACGGGACTCGAGTGATGATTGGGAGATTCCTGATGGGCAGATTACAGT
+
CCCFFFFFHHGHHJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHIIIJJIJGIGJIEHEEEHHFFFFFFDDDEDDEDDDDDDDBDDDDDDDDDC
@5L0
TTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGC
+
@CCFDFFFHHHHHJJHGIJJJJJJJJJJJJEIJJJJJFGGIIIIJGIJJJJJJJJJIJJJJJJHHHEEDFFFFFE@CEEEDDDCDCCDDDCDDDDDDDDDD
@5L1
CACCGCTGGTGGACTGTAATAATGCCCCCCTCCCTCGAGCCCTCCCTTCCACATGGATTGAAAACAAACTCTATGGCATGTCAGACCCGAACTGGCCTGG
+
CCCFFFFFHCFFHJIJIJJJJJJJJIJJJJIJJJJJJJGIJIGIJHHHHHFFEFFFEEEECDDDDDDDDDDCDDEDDCDD>CCCC@BD>BDDDDDDDCBD
@5L2
GGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGC
+
CCCFFFFFHBFDHGIGG<FEEEHEEBEFBA@FHGIIIBBDGHGIC==FGGGIG@HGGEEFBEDDBDB=CCDD?>CCDCEDDCCA8<ABDDBBB@CCDDCDA
@5L3
CAAACTGGATCCTACAGCCAAGCTCCAAGTCAATTTAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJHJJJJJJJJJJJJIJIJJJJJIJJIJJJJJJJJHHHHFFDEFFEFEEEDDDDDDDDDDDDDDDCCDCDDDDD
@5L4
CGGACCGAATCGGCTCTCTAGGCCGTGGAGCTTGCCGTCCCACCTCCGTCCAAATCGACCTTTCCTTTCTATCCCCAACCACCCCTCAACCCCTGTTTTCC
+
@@@DFFFFFHHBFHGGGHJIGHIJJGGGIIGGG@BGGFGFGGGHAEHFFFCDCECC@B??BCC>ACDCCCDACDD@?B?B<8@DD?BDCDDDD8<4>ACCC
@5L5
CAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCG
+
C@CFFDFFHHHFHJJJIJJIIIJJIJGIHGIID@FGGIJJGGGEFHIIGGEGGCCGGEHIIGJIJCHCAEDFFFFECCEEC?BDDBDDBDDDCDCDDDDED
@5L6
CTGCCATTGGCTGTGCAGGAGTGGGAGCACACCAGCAACTTTGACCGGATGATCTTTTATGAGATGGCAGAAAGGTTCATGGAGTTTGAGGCTGAGG
+
;??DBD>4ADAD?E+2C:A+ACE>?AC<@CCDDABDDCAD@DAD>><AAAA7==@CDD@CC=A>DAA@?@@AA@?AAAADBA:9AAAA:<9=<>>>>
@5L7
CCCCAATACATTATCCTGGAACTGATGGAGGGAGGAGACCTTCTTACTTATTTGCGTAAAGCCCGGATGGCAACGTTTTATGGTCCTTTACTCACCTTGGT
+
C@@DDFFFHHHHHJJJJJIJJGIIHIJJJIIJHGGGGEEHIJJJJJJIJIGGIGGJHGIJJIGHFFCADDCCABBBDDDACDD@CCCDCCCCACCBDDDD@
@5L8
CAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCAC
+
@@@=DBDFFFHGGGGGIIIIIIIHIIIIIGIIEEIHHGI@FHHGGGGHGIIIGIFGGIIEGHHHFHHH;@BDCFCCECDCBCCCDDDBDDDBABB??BBCD
@5L9
CAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATAT
+
CCCFFFFFHHHHHIJJJHIIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJHHHHFFFFFFDEEEEDDDDDDDDDDDDDDDEDEED
@5LA
CCGCCGCCTCTCCCCGGCTGAGAGAGCTCAGGGACCCAGGCCGCACCAGGAGAACAACCACCAGGAGTCCTACCCTCTGTCAGTGTCTCCCATGGAGAAT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJIJJJJJIJJJJHFFDDEDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDD@CCDCDDDDDDDDDDDD
@5LB
CCAAAGCTTTCCCCCTCCTCTGATGATTAAACAGGAACCCAGAGATTTTGCATATGACTCAGAAGTGCCTAGCTGCCACTCCATTTATATGAGGCAAGA
+
CCCFFFFFHHHHHJJJJJJIJJIJJIIJJJJIJJJJJJJJJJJJGIJJJJJJJJJJJIJJJJJJJIHJJJHHHHHHFFFFFEDEEEEDDFEDDCDDDDD
@5LC
CGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCC
+
@??;DDDDHFFAFC<?FGAGEHED?FGCBBHFEEG@77;BBGBHIAEIEE=C?EDE>C?@CCAAC@>?CA>@BBBBBBBBBBBCCA:A@CCC>CCC<<BB
@5LD
CCTGGAAGCGGGCAGATCCAGCTGTGGCAATTCCTCCTGGAGCTGCTCTCCGACAGCGCCAACGCCAGCTGTATCACCTGGGAGGGGACCAACGGGGAGTT
+
@??DDDBDBFHDD@?@BFEDF@@?FH;??<FDHI@DG>DG2=CHIEDHAEG@EFDEA<8?>@??;?BB?CC::@>3:9>9?<18055@<?A8289>B09+9
@5LE
CTCTGTTCAGGCTACGTCACTTCCCTTGTGGGAATGTCAATTACGGCTACCAGCAACAGGGCTTGCCCTTAGAAGCCGCTACTGCCCCTGGAGCTGGTCAT
+
@BCFFEFFHHHHFIJJIJIIIJJGIJJIHHIJEHIJHIIIIJJIJIGHJIIJJJJJJGIIJIGDFGFFFFFEDCECDDDDDDDDDDDDDDDBBDDDDACAC
@5LF
CGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCT
+
@@@FFFAFFFHFHEAGGHEGCEFHHIIGIEIEHIIIIIGHI>DEHIGGIIIIDHI<FHCHIIIGCEHHHHFEFDFFCCCBCC>A?C::A@CCCAAAACBBA
@5LG
TATCTACACCACGCAAAGTGATGTATGGTCTTTTGGTGTCCTGCTGTGGGAGATCGTGACCCTAGGGGGAAACCCCTATCCTGGGATTCCTCCTGAGCGGC
+
::=:B==AAAF;A8<EH;HBHCEAC??FHDGGBF@FG@:?GD9?B99?;:8C@=@D8@@@=DHAHHE83>>BCB?@?8C@A>@><+4?:@>A9?:A9C9<9
@5LH
TGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCCGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAAT
+
717<=7<=77=<A=7C?,A<<3@=ACA=72@B==:1?:*?BBAA))0-<AB<)==7=A>;7A=7;=94=5.(;;;;555=99;>55,((+::?3(+(+88(
@5LI
CAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTC
+
CCCFFFFFHHHHHJJJJJIJJJJJJJJJJJHIJJJJJJJJJJJJJJJJJJDGIJJJJJIJJJJJJJHHHHFFFFFEEEEEEDDDDDDDDDDDDDDDDDDDD
@5LJ
CAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTTATGGGCAGG
+
CCCFFFFFHHHHHJJIJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJIJIJIIJJJJJJJHHFFDEDDDDDDDDDADDDDEDDD?@>BDDDDDDDDDD
@5LK
GCGAGAGGGAGACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTAC
+
B@CFFDDFHDHHHJIGIIGHIIIIIIIJIHIJIIJGIIJJJIHHHHFFFFFDDDDDDDD@DDDDDDEEDDDDDDEDDDDDDDDDDDD&5@BDDDDDDBDD
@5LL
GACGATGCCAAGGGAAGGACGTCCTATGTACCAACGCCAGATGTCTGAGCCAAACATCCCCTTCCCACCACAAGGCTTTAAGCAGGAGTACCACGACCC
+
@@?DDDFDHDFFFGCFGHIEGIGGHFGHHGD?DHHIDHGIGIGGHGGHIBGIAHIGHFHHFFFFFECECB@BBBBBACCCCC@@CB?<?CCCCCBBB>B
@5LM
CCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTC
+
?@@DDBDDHD3F?:C<C?FGIG?@?:DGF??BD3?D@DDFH<FBFDHC;F;@C;CGGAH7?HEEA;BD>?7;;AC:C?=@B8881(:(::4(+8?889?CC
@5LN
GGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGC
+
CC@FFFFFHHHHHJJJJIJGIJHIJJIJJJJJJJJJJIJJJJJJJJJHHHHFFFFFFFEEEEEEDDDDDDDDDDDDDDDDDDDDDDDDDBCDEDDDDDDDD
@5LO
CTACACCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATGACATCTCCTGTGACTCTCACCTCTCAGACAACTAAGACAGATGACCCCCAATTGAAA
+
CCCFFFFFGHHHGIJJJJJJJJJJJJJJJJJIJHIJCDHGIJJJJJIJJIJGIIJJJJJJJIGIJJJJJIJJJJHHGGGFFFFFFEEEDDDDDDDDDD
@5LP
GACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCG
+
CCCFFFFFHHHHHJJJJJJJJJIJJJJJJJIJJJJJJJJJJJJJJJJJJIJJJJJJIJIIJJJJJJHHHHFFFFFDCEDCDDDDDDDDDDDDDDDDDDDDD
@5LQ
CCTCTCCAAATACACAGACAAACTCCAGAAAGCAAGAATGCTACTCCCACCAAAAGCATAAAACGACCATCACCAGCTGAAAAGTCACATAATTCTTGGG
+
@@@FFFDBFHFHHJ@BHICEGGAGH@HGIGIGHEEGDGII>F?FEHIDIGGHEHJICH>GIJJDGGEEF>CCECEDDDDCDDDD:ADCDDDD>B@ADCCA
@5LR
CGCTATTACTATGAGAAAGGAATTATGCAAAAGGTGGCTGGAGAGAGATATGTCTACAAGTTTGTGTGTGATCCAGAAGCCCTTTTCTCCATGGCCTTTCC
+
@C@DDDDDFHFFAHGEHGHHD:FGGI@EHGEFGGGGHIJGGGIHIGEIGIGBIHI@>BFBFHEHGGGEEGFH?HHCADDE@BEC@CCDCC:@CDBCCDDCD
@5LS
GTTTTTGGTAGCTCTTCTGGATGACCCTTCAAATTCTCATTTTATTGCCTGGACTGGTCGAGGCATGGAATTTAAACTGATTGAGCCTGAAGAGGTGGCCC
+
@?@DDDFFFHHGHGIJJJJHCHEGGIHIIJIIIJIICGHIIJIJJIJJIFHGIIJIIGHIGIIJFHHGHFFFFEFDCEEDE@CCACCDDCDD5?A59?<AB
@5LT
GAAGATTGGAGACTTTGGACTCGCCAGAGACATCTATAAAAATGATTACTATAGAAAGAGAGGGGAAGGCCTGCTCCCAGTTCGGTGGATGGCTCCAGAA
+
@@@FFFFFHHHHHJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJIIJIIJJHHFFFFDEDECDDDDDCCDDD<@BBCDDDCDDCCDD
@5LU
GAAAACACTTGGTAGACGGGACTCGAGTGATGATTGGGAGATTCCTGATGGGCAGATTACAGTGGGACAAAGAATTGGATCTGGATCATTTGGAACAGTCT
+
@@@FDDDDFBFHCEHIGHGJEHIII?DGGDHIIIIFIGGE@FGIGHHEHIJIJJJCEGE@EGCEFH?DFFFCCAECCCCAACCCCCCDCDEEDDDDDD>AC
@5LV
GAAAACACGACATGTGAATATCCTACTCTTCATGGGCTATTCCACAAAGCCACAACTGGCTATTGTTACCCAGTGGTGTGAGGGCTCCAGCTTGTATCACC
+
@CCFFFFFHGHHHJIIIJIJJJJJJJJJIIJJJEIJJIIIIJJJJJIHDHIJIJIIIGIJIJIJIIJFHHHFF?BF;A?BCEDDD@BDCACDDCBCDEEDD
@5LW
ACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCT
+
@C@FFFFDHHHHGIIGHGGGGGIEGHHIGFHDGGGGGHIHCHGGIGHGGEAHEBF>CFGGCFHGIEEECCHHBFACDBD=ACCDDDDDDDDCBD?A@@CD
@5LX
CTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACT
+
CCCFFFFFGHHHHJJJIJJIFIGIJJJJJGJJGIJJJJJJJJFGIJHIJIIJIIJJJJIJHHHHHHFFFFFFECCDACDDDBDDD>CDDDDEDDDDDDDCC
@5LY
TGGGGACTTCGGCATGTCCAGAGATGTCTACAGCACGGATTATTACAGGGTGGGAGGACACACCATGCTCCCCATTCGCTGGATGCCTCCTGAAAGCATC
+
81+:ABD?CDA6)@1CEE>E><CCE9E*:CD>9??@?D:@DBD???DA9B8@<DIDDDDD@(91=>3;AAA????:>>?;;>8>A?AA><<AA:3:A>AA
@5LZ
ATGATGGTTAAGAGGAGAGACTACTTGGACCTTGCGGCGTCCACTCCATCTGACTCCCTGATTTATGACGACGGCCTCTCAGAGGAGGAGACACCGCTGGT
+
@@@?DDAAAB?CDBH@G;?3AC@G@CBGHIGEAGFD06@F8;@7CDGACHHFHEEDBD;A>>AACDC3>,=88559>243+4(:<8?90+(+930599>B(
@5M0
CGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCG
+
CCCFFFFFHHHHHJJJGGHIHIJHIJJIIJJFJIJJJJJJIJJJJHHHFFFFEEDEEEEDDDEDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDEDDDDDDD
@5M1
GTCACATCAACGAGGAGGACACAGTGCCTCTTTCTCACTTTGATGAGAGCATGGCCTACATGCCGGAAGGGGGCTGCTGCAACCCCCACCCCTACAACGA
+
CCCFFFFFHHHHHJJJJJJIJJJIIJJJIJJJJJJJJJJJJJJJIJJJJJJJIJJJJJJJJJJJJHFFFDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDD
@5M2
TGAAGAATTAAACACAAAAATAATAGAAGAAGAAAAGAAAACTCTTGAGCTAAAGGATAAATTAACAACTGCTGATAAATTACTAGGAGAATTACAAGAAC
+
CCCFFFFFHGGHHJJJIIJIJJJJIJIJJIHIJJJJJJJJJJJJJJJJJHIIJJJIIIIJIJJJJJJJJIJJJHHHFHGFFFFFFFEEEDEDDDDDDDDDD
@5M3
CCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGGTCATTCCGACAGGACCACCCCAGTAGCATGG
+
?1?DDADA>3<DDEEIIECDED@1C<EECE4CEEFCCFF9CD>DDI;DE>BBD?=@@DADADDDD@ADD1;@AA@DDA???8529???>?>?>4(4(+:><
@5M4
CTTATTCAAACATCAACAACAGGGACCAGATAATTTTTATGGTGGGACGAGGATACCTGTCTCCAGATCTCAGTAAGGTACGGAGTAACTGTCCAAAAGC
+
CCCFFFFFHHHHHJJJJJJJJJIJJJJJJJIJJJJJJJJJJJGHIJDHJGIJIIJIJHHHGHHFFFFFFEDEEADECD5@CDDDD?CCDEDCDDDDDDDD
@5M5
GGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGG
+
@@@FFFFFHHHHGHIJIJIHIJJJJIIDGGIDH<FGGIIGIGGBEGIJIJIJHHCEHEE>@DFBC?B;=AB?BDDBCDCCCBDDCDC@C>C>?8?B<>?A@
@5M6
CAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGAC
+
@?@?ADDDH?ACF9FHFCEDBGEDDDAFBDE<?GHGCB@BGCDH?DH?B=89?98BG9F78=F=@@E@=?CCEC9(;;<;83,5,5>@CC>4:C:::>>4
@5M7
CTTTTGTAGCAGAAACATTGGAAATGGGTGAGGTTGTTGAAAAGGATACAACAGAACTCATGGAAAAACTTGAGGTAACCAAGCGAGAGAAATTAGAGCTG
+
CCCFFFDDHDHHDHIJEHIIJDHGHHJI<CGGHHEFIIEEGGHAB@FGIIGIGGDFEFHGIIJGIIJJHHFHHHFDEFDEEDA=B?BD=??AADDDCDCCD
@5M8
GACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTG
+
:=?;:2A?FF?CFDG2<?3C??;CGB@FG@GB9DB<;BB@F@?B<FFI68===FF;;=?;EC;7?D7777;AC>CA9A>??;@9<?@844::>:8??<898
@5M9
CCAAAAGCCATGAAGAGATTAATGGCAGAGTGCCTCAAAAAGAAAAGAGATGAGAGACCACTCTTTCCCCAAATTCTCGCCTCTATTGAGCTGCTGGCCCG
+
@@@DDDDDHHHDDHAGDFCBHC:FEHIIIGEFFE9GCG>FFG@>F;9B;F8?@CHCGHIDADEGII>ECEHFEEEE@@BB<>/;>CC:A::@?ACCCBBB<
@5MA
CAACTATGATGACATCAGAACGGAACTGCCTCCTGAGAAGCTCAAACTGGAGTGGGCATATGGTTATCGAGGAAAGGACTGTAGAGCTAATGTTTACCTTC
+
C@CFFFFFHFFHHJIJJBFHIJJJIJJJJIGIJIIIJJJIIJJJJGIJJJJJ@FHIIJJJIJIDHIJJHGFFFFFEEDCCD@CDCDDDDDDDCDDDDDDDD
@5MB
AGCTGGAGGCCGGCAAAGCCAAGATTGAAGAACTCTCTTTAGCTTTTCTTGTCAGACAGCTTGCCCAGTTTCGACAAAGAAAAGCTCAGTCGGATGGGC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJHIJJJIJJHHHHHFFFFFEEEDDDDDDDDDDDDDDDDDDDDDDDDDDD
@5MC
CAGCTATGAACTATGATAAACTTAGCCGTTCACTCCGCTATTACTATGAGAAAGGAATTATGCAAAAGGTGGCTGGAGAGAGATATGTCTACAAGTTTGTG
+
@@@DD;DDHH?DHGEIHGAHCA@HC4CAGA33CB?@CDGHGHI9DB?FGG?G@FCHEDGEGGEHIEEHH=C?CHDBBB@;5=B>@CA5;(>3@AC@CDC<?
@5MD
GTATGCTTGCCTTCTCAAAGTAAAAGATGATTTAGAAGACAGTAAAAATAAACAGGAATTAGAGTATAAAAGTAAACTTAAAGCACTTAATGAAGAGCTTC
+
CCCFFFFFHHHHHIJJJJJJFHJJJJIJJIJJJIJJJJJJJJIJJJJJJJJJJJJJJJJJJJHJFGHIJJJJCHIJJJIJHHHHHHFFFFEEEECDEEDDD
@5ME
CCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGC
+
@CCFFFFFHGHHHJJJJIJJJJJJJJIIJJJJJIJJIJJJJJJJJJJJJJJJIJJJIJJJJIIJJJJHHHHHFFFFDEDDEDDDDDDDDDDDDDDDDD
@5MF
CAGAAGGCTGTATGTTTGAAAAGGGCCCCAGGCAGTTTTATGATGACACCTGTGTTGTCCCAGAAAAATTCGATGGAGACATCAAACAAGAGCCAGGAATG
+
@@?D?:B+=AAFB@FEGHEHHEHGAGFGIIEGACCHHIIG@GA@F9DGGG9F8B=CEHG>>>=CHIH=?7@=BDDC@;CAC;@C@A;<939<<9??B<?3@
@5MG
CTCCGGTCCCCCCTGGACAACATGATCCGCCGCCTCTCCCCGGCTGAGAGAGCTCAGGGACCCAGGCCGCACCAGGAGAACAACCACCAGGAGTCCTACCC
+
CCCFFFFFHHHHHJIJJJJIIIJIIIJJJJJJHIGJGIJJHHFFDDDDDDDDDDCDDDDBDDDDDDBDDDDDDDDDBDBDCDCDDBDDBDDBDACDDDDDD
@5MH
CAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGG
+
C@@FFFDDHF@FDBFHGEIB>EGEFHGHIDEGCAGEEGIEGFGHGIB@F>BCFGIIIGDHIHHDA==AADCDDCDBBD@BCBDDDDDC@@95@CCACDCDB
@5MI
CTGGACAGTTACCTTATTCAAACATCAACAACAGGGACCAGATAATTTTTATGGTGGGACGAGGATACCTGTCTCCAGATCTCAGTAAGGTACGGAGTAAC
+
@@@FDDFFHHDDHEHGIJJJIJGIJJIJIHIIIGHHGIIGIJHIGIFIIJIJIG?DGGEGGHEED>B@DCECAACCCCCCDDDDC:>CCD:ACDBDD8ACC
@5MJ
TGAATTCTGGCCTCAACAAAAGTCCTCCCCTTGGAGGGGCACAAACGATCAGTAAGAATACAGAGCAACGGCCCCAGCCAGATCCGTATCAGATCCTGGGC
+
<@<B;DDDBDADDHBFGAFHD>HGGEHIIIIII@?GDEGIIIEEGHE<GCHGCHGE@?HEEHHF>BC>A>>BBB=?<<BB?ACCCB<A88:>CCCCACCBB
@5MK
TGGAGGAATCTGTTCAACATGTTGTCATGACAGCCATTCAAGAGCTGATGAGTAAAGAATCTCCTGTCTCTGCTGGAAATGATGCCTATGTTGACCTTGAT
+
CCCFFFFFHHHHHJJJJJJJJIIJJJIJJIIJGIGHIIIJIJEIGIIHIIIIDGIIGIIJJJJJJJJJJIJJIIIJJHHHHHHHFFFFFDEEEEEEDDDDD
@5ML
CCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAAC
+
@<<DDDEDFAADFHEHCHGIIJGIGIIGGIIAHGHIIIICH@FHCBB4BGDFE@DEE@G@FAGEGEFHDF@EFC<A>@A>>C>;CCCCC:::CACDBCCD
@5MM
TGATGATTAAACAGGAACCCAGAGATTTTGCATATGACTCAGAAGTGCCTAGCTGCCACTCCATTTATATGAGGCAAGAAGGCTTCCTGGCTCATCCCAGC
+
@@?DDFFFHHGDHJIJJHCGGE?FFGHHIJEIIHIIFHIJBEHGICFFEHCHCDD>BFBFHIEGIGHICFHEIHCCHHFFFFDECEECEDBDDCCCDDCCD
@5MN
TCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATG
+
CCCFFFFFHGHHHJJIIJJJJJJIIJIJIIJJIIJJJJJJ<FHIIIIIJJJEEFHHHFFFFFFDCEDDDDDCDDDDDDCCDCDDD?BDBBDDBBDDDDDDD
@5MO
GTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGC
+
@:?DDDDDFFFFD?EBF>BFG3F<G8?DFGIIEFFAAFFCFFFAFFEFIIIFF>=;?>BD@>BCACCDCB;@BA@@B?>AAB>ABBBB9?@A????99>
@5MP
TATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTAC
+
CCCFFFFFDFBFHHGIIIIIJIJIIIIJIIGEEHIIIJIGIIIIIJJJJJIIIIJIGHC@FHGHIIEHHHHHHFFFFBEDDCDDCDBCDBCDDDEEDDDCC
@5MQ
CAGTCATGTGATACTCAAGTAAGCTCTTTATTAGATGGAGTTGTGACTATGACAAGCAGGGGTGCTGAAGGATCAGTTTCTAAAGTAAATAAAAGTTTTGG
+
CCCFFFFFHHGHHJJJJJIHIJJJJIJJJIJJJJGIIJHIGHIHJIIIJIIIJJJJIIIHII@FHJJJIHHHFFFFFFFDFEEEEDEEDEEDDCD@CDDDD
@5MR
CGATGCCAAGGGAAGGACGTCCTATGTACCAACGCCAGATGTCTGAGCCAAACATCCCCTTCCCACCACAAGGCTTTAAGCAGGAGTACCACGACCCAGTG
+
CCCFFFFFHHGFDGIJFHIEGGIJJIIJIJIGIIIIJIHJJIIIHIJIJGIIJJJIIHHHHFFFFFDDDDDDDBCDDDDDDDDDBDDDDCCCBDDDDBBAC
@5MS
CCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGCGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTTATGGGCAGGAGT
+
;??DDDB;D:AFAFG@DGED4F<3C1;E2CCCECC)C?9D)?DG@?FG2('(55=7).@?8ABDA2?C?BBB=??(:>CCDCB<39)(94>4>8+(0<(8+
@5MT
GTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGC
+
CCCFFFFFHGGHHJJJJJJJJJJIJJJJIJIJJJIJIBGIIJJJJJJJJJJIFHHFFFFEEEEEEDDDDDEDDDDDDDDDDDDDDDDDDEDDDDDDDDDDD
@5MU
GCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGC
+
??;;DADBC:CFHGEGHIIGGIC<EEHGGHEG<FGHD<BAEBFGD@A9FFH9CG=D@HC@CCAHE;A;?ECDCE9A?A>CCC@A;A>@CCC@B>C::>?8
@5MV
CCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAAC
+
CCCFFFFFHHHGHJIJIJEEHAFFHGIIIIIJJJJJIJIJIJJJIIJIHIJJIJJJJJIJGIIJHHGHFEFFFFCDEEEEEDDDDDDDDDCDDDDDDDDC
@5MW
TGCTACTCCCACCAAAAGCATAAAACGACCATCACCAGCTGAAAAGTCACATAATTCTTGGGAAAATTCAGATGATAGCCGTAATAAATTGTCGAAAATAC
+
CCCFFFFFHHGGHJIJJJIJJJJJJJJJJJJJJJJJIJJIJJJJJJGIIIJJJJJJJJJJJJIHHHHHEFFDFDFEEEEEDDDDDEDDEECCDDDDDDDDD
@5MX
CAGATTTCGCCGCCAGCTTTCTGAACCCTGTAACTCCTTTCCTCCTTTGCCGACGATGCCAAGGGAAGGACGTCCTATGTACCAACGCCAGATGTCTGAGC
+
CCCFFFFFHHHHGJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJIJJJJJJJJIFFFFDEEEDDDDDDDDDDDDDDDDDDEEDDDDBDDDDDDDDCEDDDD
@5MY
AAAGACAGCCAGTTCGAAACTGATATAGTACAACGAATGGAACAAGAAACACAAAGAAAGTTAGAACAACTCCGGGCAGAGCTGGATGAGATGTATGGGC
+
==>AA>AABAA2+<=CA>C7>+<ABB721111?AAAABB*7<*=AB>>ABB<7=B>BBB3)7>>>7AA9.)77(/''9;=59;=:(5999:38?8;;;;;
@5MZ
CACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTC
+
C@@FFFFFGD@DFGIIGIGEGGGGGEGHGGEIIIIGIEGDHIHGGJJJGIJAGHBHHHDDEF6>ACECDB@???CCDD@D?<>CCDDDD>@>CCCCDCCC@
@5N0
ATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGC
+
@@@DFFFFHHHHHJJIIIFGIIJIIFIJIJJJIJJIJIIJJGJJJJJJIHHIGIIJJJJGIJJIIIIAEHFCDFFDDFEDEEDDDCCCBDDDDDBBDDDD
@5N1
GATGGACAGCAGATACTTGTGCCCAGCAATCAGGTGGTCGTACAAACTGCATCAGGAGATATGCAAACATATCAGATCCGAACTACACCTTCAGCTACTTC
+
@@@DDFFFHGHHHIJJIJIHGHIJIHJJIJIJJIGHIFGG@FGHIGHGIFGBGIGAFIIIJJJJIIGHHHHC?DECCCEDDDDDDDDDDDDDCDDDDDDDD
@5N2
GAGAGGGAGACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGT
+
B@@FFFFFHHHHHJJJIJJJJJIIJJIGGIDGGHIIJIJJJJJJHGHHHFFDDDDDDDDDDDDDDCCDDDDDEDDDDDDDDDDDDDDDDCDDDDDDDDDDB
@5N3
GAGAAAATGGCGTCCACGGATTACAGTACCTAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACC
+
CCCFFFFFHHHHHIJJIJJJJJJJJJJJJJJJHIJJJJJJJJJJJJJJJJJHHHFFFFFEEEEEEEDDDDDDDDDDDDDDDDDDDCDDDDDDDEDDDDDD
@5N4
CGGCAAAAGATATGCTTACAAATTTGACTTCCACGGCATTGCCCAGGCTCTGCAGCCACATCCGACCGAGTCGTCCATGTACAAGTACCCTTCTGACATCT
+
@@@FFFFFHGGHHBAEGIIJJJJIJJGHIIIHHIJFIIHEFCHGGGIJJIIIGGGJGEGBEDGEEEEA;>B<8?B@@D@DCDECCACCDDDDDCDDDDDDC
@5N5
ACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGAC
+
?@@DDDFFHHHHGEHIJJJGIGHII@GHGCHGHGHIJIDFAFHIEIIDFHIIJJIIJGFEAEEHFFFB=AB;8ACDDDDB?BDB?2?@CCCCC@CCCDCD
@5N6
CAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTTATGGGCAGG
+
@@@DDDD?FH?FFGBHG<EIG@BFC+<CFH)1:?FHEHG;:*:@@?(?AD>@@GC;D;C>;=7'-=/5>6(;;;9?BB:C:5>@@?A>9BBC:(448((50
@5N7
CCCTATTACTTTTTTTAAATGCCATTAGTTCTGTGTGCTATTGGTGTTTATTTGCATCCACCTGTCCAGTTGCTCTGCTGTCTTGTGTTTTTGCAGCCTCT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJIJHIJJJIIHGIJJJJJJDGIJJJJJJJJIIIJJJJJJJJJJHHHHHHFFFFFFEEEEECC?CDDDBCEDDDDDD
@5N8
CTCCGGGCAGAGCTGGATGAGATGTATGGGCAGCAGATAGTGCAAATGAAACAAGAATTAATAAGACAACACATGGCACAGATGGAGGAAATGAAAACACG
+
?@@DDFFFGDDHFIIDGIHIGDFFGIIIIIIGIIIIIIIIDFHIIIIIIIIDHGGIGIHIHHGIHHHHHDBDFEEECCCCCCCCCDDDDDDDCDDDDDDDD
@5N9
GAAAAAGAAAAGAATGCTGTGTTAGACAGAATGGCTGAATCACAAGAAGCTGAATTAGAGAGGCTGAGAACACAGCTTCTATTTAGTCACGAAGAAGAGCT
+
CCCFFFFFHHHHHJJJJIJHGIJJJJJJJIIJIJJIJJJJIJJJJJJJJIJJIIIIJJIIJJJJJJJIHHFHGFFFFEEECEEEEDCCDDDDDBDDDDBCC
@5NA
AAAAGAAAAGAGATGAGAGACCACTCTTTCCCCAAATTCTCGCCTCTATTGAGCTGCTGGCCCGCTCATTGCCAAAAATTCACCGCAGTGCATCAGAACCC
+
CCCFFFFFHHHHGJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHFFDEEEEDDDDDDDDDDDDDDDDDDDDEDDDDDDDD
@5NB
CGCCATGGCTTTGAACTCAGGGTCACCACCAGCTATTGGACCTTACTATGAAAACCATGAATACCAACCGGAAAACCCCTATCCCGCCCAGCCCACTGTGG
+
;==A+7+?A@+<7?B77=7=AA3<3++<)?5?;?B<?7?>A;AA799=AB=*0=BA23)./)/=ABB=<A@999>>;;:;=:=>>=6&)&22899;;88:8
@5NC
CAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHHHHHFFFFFEEEEEEEDCDDDDDDDDDCDDDDDDD
@5ND
CCAAGATTGGAGACTTCGGGATGGCCCGAGACATCTACAGGGCGAGCTACTATAGAAAGGGAGGCTGTGCCATGCTGCCAGTTAAGTGGATGCCCCCAG
+
:=@;=2ABD8?AFH@CA<@@@GH=EHB?F6FDHGD<??9??61;-5-=;C>77@>C@;;@?@;8<2555>:@::9@:4+>4>:@D@+++:A:24985@<
@5NE
AGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAA
+
BCBDFFFFHHHHHJIJJJJJJJIJJJJJJJJJJIJJJJIGIJJJJJJJJIJJHHFGFFFFEEEEEDDDDDDEDDDDDDDDDDDDDDDDDDEDDCDDDDD
@5NF
GGAAGAGTTAAGAAAGGCCAACGCAGCGCGAAGTCAACTTGAAACCTACAAGAGACAGGTAGTAGAACTACAAAACAGATTATCCGAAGAATCAAAGAA
+
CC@FFFFFHHHHHJJJJJJJJJJIJJJJJIIJIFFHGIJJJGGGHIIJHHHHGFFFFEDACCCDDDDDDDCDDDDDDDDDDCDDDDDDBDDDDCDDDDD
@5NG
CATCTCCAAACTCAACTCATACACCGAAACCTGACCGGGCCTTCCCAGCTCACCTCCCTCCATCGCAGTCCATACCAGATAGCAGCTACCCCATGGACC
+
@@CFFFFFHHHHGIJJJJJIJJJJJJJJJJJJJIJJJJJJJJJJJJIJJJJJHHHHFFEFDEEEDDDD?CDDEDDDDDDCDDDDCDDCCDDDBCDDDDD
@5NH
AGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAAC
+
@CBFFFFFHHHHHJJJJJJJJJJJJJJJJJIJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHHHHFFFFFFEEEEEEDDDDDDDDDDDDDDDDDD
@5NI
CTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTAT
+
@@@FFFFFGGGGFGIGHHGIGIJIIIGJIIJIGHHIGGIJJ@AG>FAEGHJDEEEHHFFFFFFCDACDDD<CDDDDDDCDCCDCBBBDDDBDDDDCBDDDA
@5NJ
CTCAAACACGGAGGTCATTGAGTGCATTACCCAAGGTCGTGTTTTGGAGCGGCCCCGAGTCTGCCCCAAAGAGGTGTACGATGTCATGCTGGGGTGCTGGC
+
@@@D?DDDFFFFDH;E?EEE4FBGIDCGHHIGIGIIDDF?F@FDBCADAE@B/=D>A8;;?CCCCBB<<19>C@4<+4:?@B?8AA@>C>ACBB09@CCCB
@5NK
TATTTCTGCTGCAAGTACTTCTGATGTTCAAGATCGCCTGTCAGCTCTTGAGTCACGAGTTCAGCAACAAGAAGATGAAATCACTGTGCTAAAGGCGGCTT
+
CCCFFFFFHHGHHJJ<FGGJIJJIJJJJJJJJJIJIIJJJFHHIJJJJJIHIHHHIJJJHGIIJJJJJJJJJHHHHHFFFFFFEECEEEEDDDDDDDDDDD
@5NL
CAACTTCAGTTATTCAGAAATTTTTTCTTAAATAGCATTTATAAGTCCAGAGATGAAGCAAACAACAGTGGAGTCATAAATGAAAGCTTTGAAGGCGA
+
8:+4=:;??=:DC9:<AAFECDE4?1C?B@B*1@DEDDD***1*00*0*09B)939D?88B@C;BC6@@AA)=..7=>3A3).3.7;>;>@(;>>(,'
@5NM
CAGTGTGTTCACACTTTGTCAGATGAGAAATGGGATGTTATTAACTGGAGGAGGGAAAGACAGAAAAATAATTCTGTGGGATCATGATCTGAATCCTGAA
+
CCCFFDDFHHHHHJIGIJHDIIHIJHEFHIJIIJEHIJIGIJIJGHGIHII=FHIBGEHGHIJIJJJHFHHEHDFFFFFDAACDDDDDDDDDDDDDDDDD
@5NN
CAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTC
+
?<@?DDDBHHHFBHGB:<FDBFFHHGEDHI:CGH<DCDHDGDHHICF96?/?@CBHBB25@AAGHHEEHEBD>@BCCAC@CCA>>CC>ABC:CBCCABBCA
@5NO
CAAATTCGAGCATCACCTTCTCCCCAGCCCTCTTCACAACCTCTCCAAATACACAGACAAACTCCAGAAAGCAAGAATGCTACTCCCACCAAAAGCATAA
+
CCCFFFFFGFFDFIGIIJGGGIJJIGJJJIIGDEHGIJJIIIGGGGCGIGIIEEHCAFFDGGIJJHGHHHFFFFFEDCC>@AC>CDDDDDDDDBDDDDDC
@5NP
CCACTGCATCATGCATCTCCAAACTCAACTCATACACCGAAACCTGACCGGGCCTTCCCAGCTCACCTCCCTCCATCGCAGTCCATACCAGATAGCAGCT
+
CCCFFFFFHHGHHIJJJIJJJJJJJJJJJJIGIIIIJJJJJJJJJJJJJJJJJJHGGHHEDFFFDEEEEBDCDDDDDDDDDDDDDDDDDDDDDDDDDDDD
@5NQ
GTGAAATGCCTTGCTATACATCCTGACAAAATTAGGATTGCAACTGGACAGATAGCTGGCGTGGATAAAGATGGAAGGCCTCTACAACCCCACGTCAGAGT
+
@B@FFFDEHHGHGJJJJJJJJIIIJIGJGIJIIGHIJIGIJIIIIIJDCHG?DHIGIJIDG5@EHHGHHFHHHHFFDFDDCCEDDDDDDDDDDBDDDDDD>
@5NR
TACTTCTCTGCCACAAACTGTGGTGATGACATCTCCTGTGACTCTCACCTCTCAGACAACTAAGACAGATGACCCCCAATTGAAAAGAGAAATAAGGTTA
+
?@@DFFFFADBHDGEGEAHEHG>ACE>D9CEGGHGJ@?:?CCDBHG9BGGHCGIGIIGGIGGIIFFGGEHIAHIHHFB=@C@@CCAC;A?ACCCCCD:@C
@5NS
CGACGGCCTCTCAGAGGAGGAGACACCGCTGGGGGACTGTAATAATGCCCCCCTCCCTCGAGCCCTCCCTTCCACATGGATTGAAAACAAACTCTATGGC
+
@<@?BD:DADF??:E@EA?8C7DDF910)8?@1:AF;?=.7=7=@@B>?B=@=88853,5))55?B@B<BB<>3>@::3(4@<(>::>22(((44+(((2
@5NT
CAACCTTCTGAAGACCGGCCACCGGATGGAGAGGCCAGACAACTGCAGCGAGGAGATGTACCGCCTGATGCTGCAATGCTGGAAGCAGGAGCCGGACAAA
+
CCCFFFFFHHHHHJIJJJJIIIIHGFHHIHIGIJJJJJIJJGGHJJJHFHDFDCDDCDCCFDBDDDDDDDCCDDDDDDDDDDDDDDCDDBDBDDDBDDDD
@5NU
AGCAGTTATTCCCAGGTCCTGTATAACCAATGGAAGGGGTGCAAACAGAAAACCAAGTCATACCAGTGCTGTCTCAATTGCAGGAAAAGAAACTCTTTCAT
+
;=;AAAAABB4ABC+2?C>7CBBBABB>?CBAAAAA)?A?==A*=>>ABBBB;ABBB==77>BBAAAAA;=.;>;;?@>>@5>=;;;558==??:=????=
@5NV
TTTGTCAGATGAGAAATGGGATGTTATTAACTGGAGGAGGGAAAGACAGAAAAATAATTCTGTGGGATCATGATCTGAATCCTGAAAGAGAAATAGAGGTT
+
CCCFFFFFHHHHHHIJIIJJGIIHJIIJJJJJJJHIJBHIJHIJJJJJJIIJJJJJJJJIJJEHIIEHHHHFFFFFFFEEEEEECDDCACCDDDDDDDD>B
@5NW
CTCAAATAAAGAAGAAATACAGGAAAAGGAGACAATCATTGAAGAATTAAACACAAAAATAATAGAAGAAGAAAAGAAAACTCTTGAGCTAAAGGATAAAT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJIIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJHHHHHFFFFEEEEEDDDDDDDDDDDDDDDE
@5NX
CCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTTATGGGCAGGAGT
+
@@@DD=BAFD?FDHBGFHBFHHIEFAHH@;;EEFG@>FF@:@DH:FBFGGG77@@GGBGCE:A??>B==ACBB?BACC@>CCBB,9@BAC:CCB89>B<@9
@5NY
CTGGAGGAGGGAAAGACAGAAAAATAATTCTGTGGGATCATGATCTGAATCCTGAAAGAGAAATAGAGGTTCCTGATCAGTATGGCACAATCAGAGCTGT
+
BBCFDEFDHHHHHJJJIJJIJJJJJJJJJJJJJJJJHJJJJJJJJJJJJJJJIJIJJJIIHIJIIIHHHHHFFFFFFEEEEEEEDDDDDDDDDDDDDDDD
@5NZ
ATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGC
+
1;@B?D:AFD?FA?F9EGCCBF<:C?+<:FGCDFIBF=G3FF>B<??3//*8BCDA<FC@AFA=EFE:>73;;;@@@@C>:3==;>;@==?;(5<??<<B
@5O0
GTGTGATCCAGAAGCCCTTTTCTCCATGGCCTTTCCAGATAATCAGCGTCCACTGCTGAAGACAGACATGGAACGTCACATCAACGAGGAGGACACAGTGC
+
?@<B:D44A:=C:AB;ECFFH<:,A?+A;D;CEFEIFFI@BG<BGDD:?DAD<88=8BFFECFF@C@D@@93=;'?==;;;@>A?8?6/'88?<<?9?:>>
@5O1
CCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTAT
+
CCCFFFDFFHGHHBHIJJIJIJIJJIJIJJGJJJFHIJJIJJJJJJJIJJIHHEFFFFFECEEEDDCDDDDCBDDBDDDDDDDCDCEDDDDDDDDDDDDDD
@5O2
GTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGC
+
CCCFFFFFHHHHHJJJJJJJJJGGIJIJJGHJJJIJJJIGHIFIIJJJIIJJIJJJJIJIJIFHHHHHFEFFFFEEEECEEDDDDDCDBCACDDDDDDB
@5O3
ATAAAGACAGCCAGTTCGAAACTGATATAGTACAACGAATGGAACAAGAAACACAAAGAAAGTTAGAACAACTCCGGGCAGAGCTGGATGAGATGTATGGG
+
@@@ADDD?FFHHFG<CA;FHIEHIIICGHF:???FGGGGD;BHFDAFFDFH@FFBGGGGGHEHG@>ACAEEBCEF=>CBCB?93>CCACCC>:4@CC>>CB
@5O4
TGAACTTCAAAAAGAAATTGAAATACTCAGACAAGAAGAAAAAGAAAAGGGTACACTTGAACAAGAAGTTCAAGAATTACAACTTAAAACAGAATTGTT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJIJIIJJJJJJJJJJJJGHIJJJJJJJIJJJJJJHHHHHHFFFFFFEEEEEEDDDDDDDDDDDCD
@5O5
CTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTAT
+
@@@BDDDBDFFB;?@F>GE;E?EAEDGI9<??G@C?91C=@@)6@G?BDGIIE<BC7=3=7@7C;.7;=??EH;CC?A>=C>@@C<?5?9?BBB<99?A@A
@5O6
GAAGGCTTCCTGGCTCATCCCAGCAGAACAGAAGGCTGTATGTTTGAAAAGGGCCCCAGGCAGTTTTATGATGACACCTGTGTTGTCCCAGAAAAATTCG
+
@@CDDDFDFFHFFEHHIGGIFFHHGHAHGHFFFBEGIGIIGGIJIF@FGGDHEEGGIJJJJJFHHDHEDFBF@>?>;ACEA>CABADC:@:?ACA?BCCB
@5O7
CTAACAGTCCAGCAGGAAGAAGGCATTTGCAGCTCCAGACTCAATTAGAACAGCTCCAAGAAGAAACATTCAGACTAGAAGCAGCCAAAGGTGATTATCG
+
CCCFFFFFHHHHHJJJGJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJIJJIJJJJJJIJJJJJIJJJHHHHHHFFFFFCCECDBDDDD5>CCEEDDD
@5O8
CAAACTTATAGATATTGCACGACAGACTGCACAGGGCATGGATTACTTACACGCCAAGTCAATCATCCACAGAGACCTCAAGAGTAATAATATATTTCTTC
+
@CCFFFFFHHGBHIIIIIIIJJIJJJJJIHIJJJJJJJJIJJJIJJJJJIJJJIIJJJHGHJHHHHHHFFFFFEEDDDDDDDCB5>CDDDDEEEEEEFEDD
@5O9
GGCTTCTCGTCCTCAGAGTCGGAGAGCTCCAGTGAGTCCAGCTCCTCTGACAGCGAAGACTCCGAAACAGAGATGGCTCCGAAGTCAAAAAAGAAGGGGC
+
CCCFFFFFHHHHHJJJJIHIJJIIGHIIJJJJGIJIHIJJJJJJJJJJJHIJJIIJJHHHFFFFDDDDDDDDDDDDDDDDDBDDBDDDDDDDDDDDDDDD
@5OA
CCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGC
+
CCCFFFEFHHHHHJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJIJJJJJJJJJJJIJJJJJJJJJHHHHHHFFFFFFEEEDDDCDDDDDDEEDDEDEDDDD
@5OB
ACTTAATGAAGCACATAAGTCCCTTAGTACAGTGGAAGATTTGAAAGCTGAGATTGTTTCTGCATCTGAATCCAGAAAGGAACTAGAATTAAAACATGA
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJHIJJJHHJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJIJGHHHFFFFFFFEEEEDDDD
@5OC
TGTTAGTAGATCTTGTTGTCAGTCTGTGATATTGATGATCATCCTGAATTTTAAATGACAGTTGGGATTGGGATGGGTTTTGTGGTCATGGGAACATAAA
+
?@@DDFDDHBDFHHGFHGGIGIFHHGAEB?FFHH<EHIC<GGIIIIIGHIIIIIIIIHIICHHIIICHIIIEEHHII=EHFEFDBEEDEECDDDBDDCCD
@5OD
CCGGGTCAGGACGGTACGGAGTGGAACACTAAAGTCTCAGAAAGAAGGAGTTAGTGCTTGATACTTAGGAGCTTGGAAGACGAAAAGGGGTAGAAGATGA
+
11+++00<733+?1?+)1))0)))0*0)?7>>AA*9*/**0)))95)8=().))))))))..)7))7.(..((((,(-(5('86;-809&)&+83;+(5(
@5OE
TTGATGTGTTAAACTATGTGCAAACAGGAGGGAGACTGGAGCCACCAAGAAATTGTCCTGATGATCTGTGGAATTTAATGACCCAGTGCTGGGCTCAAGA
+
<@@=DDDD?FDHFIGIG<ACF>ECGHGIDGGIG@):BCG@GDH@HEE?HD3=CG@@FDHHA@E;CAGE=CHH>@D>CEECCCC@BA;>@;@C@BCBCCC>
@5OF
AATGAACTGAATATAAAATTGCAAGATACTAACTCTCAAAAGGAAAAACTCAAGGAAGAACTAGGACTAATTTTAGAAGAAAAGGGTGCTCTACAGAGAC
+
8?<D?ADADA:CFFHB<C3C<IBEFHEH@BHHIAF@GAEED9)3?DB@0BD<GHIIABF8=BF:37.@C=CD@DGHE377;BEE(5;;;>@ACCCCCCCC
@5OG
GGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCAT
+
@@@DDDD?H?FD?EAGACCG<C?@@1:CEEG;FDBG0?GHII9D99?BHH@FHII@=FFC@A7CECHHCAA?B>A=1=;3=@C@(5:@CC>CCCAC@:@C>
@5OH
TGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTCGCAC
+
1;?11DB?DD3AD;?:2+<CBCFEDDIED<DDD9D>:?D*?BD>3BDD;8BAD6;/(7)5;?>AA>;;1;?=;;>>AAA>A5:>AA?A?:(+44(+2&)
@5OI
ACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACT
+
@C@FFFFFFFHHHFIIIIIJJIIJIJIGJGJIGHIHIJFHIGIJJGGIJGHGGHIJJJHGED9;ACDC:<@BBBB@BDDDC?CDDDDCCCCCBCDCDCCD
@5OJ
GTACCAACGCCAGATGTCTGAGCCAAACATCCCCTTCCCACCACAAGGCTTTAAGCAGGAGTACCACGACCCAGTGTATGAACACAACACCATGGTTGGC
+
C@CFFFFFHHHHGIJJIIJJJJJJJJJJIJJIJJJJJJJJJIJJJJJJJIJJJJJJJJJHHEEEFFFFDDDDDDACCDEEDECDCDDDDDDDCDD@CBDD
@5OK
GTGAGCTCCGCCAACAGTTACAGGCTGAACCTACACCTGAGGAGCCTCCTTAGTAGTCTGCAGCGACTGCTTCTGCCGCCCTTAGAGAGGGCAGTGGGA
+
00(2()22)(0(((-(.)22:69<1;3@<3?7:)<79>1:)(.-(-).<))...))/.)..=)6''',3=;<(9=39'3',)(+((5(220060+6/((
@5OL
ACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGG
+
@@@D=D1A<D<D?DFHI@@FDAHFHEGG9FBDGH@GADD<@BB8=FC8CFGHIIEC=54AD<?BCCBBACACCCBCC@>CDCCCCBBCBBBBBBBBCCAC:
@5OM
AGCCGTTCACTCCGCTATTACTATGAGAAAGGAATTATGCAAAAGATAATCAGCGTCCACTGCTGAAGACAGACATGGAACGTCACATCAACGAGGAGGAC
+
CCCFFFFFHHGHHIIJJJJJJJIJIHIHIJJJJJJJIJJIJJJJIHEGIIIJJIJIJJIJJJGJJFHHHHFFFDFDEEEEDDDDDDDDDDDDDDDDDDDDD
@5ON
CCGAAACCTGACCGGGCCTTCCCAGCTCACCTCCCTCCATCGCAGTCCATACCAGATAGCAGCTACCCCATGGACCACAGATTTCGCCGCCAGCTTTCTG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJIJJJJJJIJJHJJJJHHHHHFFFFFFEEEEEDDDDDDDDDDDDDDCDDDDCDDDDDDDDDDDDDD
@5OO
CCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAAC
+
C@@DFBDEHHDHDGGGHEHGEIJIIJJJJJIGIIJJ@FHIJIIEGEIGGGIGGIEEFFFFFBCCCEECCC>ACCDBDDDDCDCDCC@CDCBDDD5>ACDDC
@5OP
GGAAAAACTTGAGGTAACCAAGCGAGAGAAATTAGAGCTGTCACAGAGACTGTCTGATCTTTCTGAACAATTGAAACAGAAACATGGTGAGATTAGTTTTC
+
CC@FFFFFHHHHHIHHIJJJJIIGHIIJIIJJJIIJJJJJIDHIIIJIJJIJJIJJJJJJJIIJJIJJJHHHHHFFFFFEEEECEDDACABCDDDDDDEDD
@5OQ
CTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATG
+
@@@?DBDDDFFD?AE@FHIFGGGHA?6CGHGHHIFII<FHGICAGIHIIIFEHHDEEEECCCCA@C@@A=CBBCB?@@BBBBCC@CC?BCBBBB?C?CCCC
@5OR
GAAAATGTTGAATGTGACAGCACCTACACCTCAGCAGTTACAAGCCTTCAAAAATGAAGTAGGAGTACTCAGGAAAACACGACATGTGAATATCCTACTCT
+
@<@DADFDFFHDDHGGIEBHABGHGICAGHIIGIIGIGDIIIIEGGGHGAFGGGDHGHIBFDGIG8@FHGAGGEEHCE=DEBC8@C;@DD@>@CDCCCCCC
@5OS
ATTTGGTTGAGAGTGTCTGAGGAGGCTACCGATTGGTTGCAATGTTTAGAAGTTCTTTTATTCCGATCTCCGCAGCAGCCTACTCCCTTGGTCCTGTACGC
+
(((2(:>5(.9(2.2))).6;3)8/3(9).((((((0(((9))))))/)))).83));9)<)6)69;'69)''95',((,8,(,,:(+2+(+(5(+++(+)
@5OT
TAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACT
+
CCCFFFFFHHGHHJJJJJJJHIIJJJJJIJJJJJJJJJJJJJJJJJJIJJJJJJJJIIJJJJJJJJJHHHHFFFFFEEDEEDDEEDDDDDDDDDDDDDDD
@5OU
CAACTACAGTGAAAATGAAAAGTTCTGTCTTTGATGAAGACAAAACTTTTGTAGCAGAAACATTGGAAATGGGTGAGGTTGTTGAAAAGGATACAACAGA
+
CCCFFFFFHHHFHJJJJJJJJJJIJJJGJJIJJJJJIJJJIJJJJJJJJJJHJJJJIHJJJIJIJJIIIJJJJ@GEIHEHHFFFFFEEEDDDDDDDDDDD
@5OV
CAGGGACTTCAGACATTAACCATGACAAATTCAGGCAGTACTCAGCAAGGTACAACTATTCTTCAGTATGCACAGACCTCTGATGGACAGCAGATACTTGT
+
B@@DFFFFHGHHHCHJJJIJIJIIJDHEGHHHIHIGEHIEHIIIJEIIIEDGHHHGGFGGJGGIIIEIGIJEHIGJJHHGHG>@CCCCCCBEACCDDDDDC
@5OW
CCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCG
+
C@@FFDFFDHFDHJJGCGIJIIJJJJJJIJGGIJFIJIIGDGIGIIJIJIJIJJJJJJIEHIIJGJGEGFEEFEFFE@EECECDDCDDDCDDDDD
@5OX
CAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCAC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJIJJJIIJJJJJJJIJJJJJJJJJJJJJJJJIJJGIHHHHHHHCEFFFFDECEDDDDDDDDDDDDDDDDDDDDDDD
@5OY
ATCCAGCACGCCAGTGTCCCCACTGCATCATGCATCTCCAAACTCAACTCATACACCGAAACCTGACCGGGCCTTCCCAGCTCACCTCCCTCCATCGCAGT
+
CCCFFDFDDAFAAHFGGHIIJJICIIIGGGCCEGGGGIJIJJJIIIIIEIGCFGGIJGHGIGHCEDDFFDDD@?CCCD@CACCACBCDDDDDBDDDDBDBB
@5OZ
CAGTTTCTAAAGTAAATAAAAGTTTTGGTGAAGAATCAAAAATAATGGTGGAAGATAAAGTTTCTTTTGAAAATATGACTGTTGGAGAAGAAAGTAAGCA
+
CCCFFFFFHHHHHJJJJJJJJJHJJJJJFHJJJJJJJJJJJJJJJJJJBGIGHIJIJJJJHIJJJJJJIHIJJJIJJJHHHHHHFEFFFEDEEECCDDDD
@5P0
CAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGC
+
C@@FFFFDHHHGHJIFIEG<FGFCFFHIIJFGIJJIJIFIJIHGGIGHIGCHHII<FHHIJIIJGFHGBBFFDEEDECDCCCCADDDDDACDDDDD>ACB
@5P1
GTTACCTTATTCAAACATCAACAACAGGGACCAGATAATTTTTATGGTGGGACGAGGATACCTGTCTCCAGATCTCAGTAAGGTACGGAGTAACTGTCCA
+
@CCFFFFFHHHFFGIJIIJJJIIJIJJJJJJIJJJIIIIJJJJIJJIHIIJIGGIGGICHHHHEFFFFFFDECDEEDDCDDDD5@A@B?B?CCCDDCDDD
@5P2
ACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGT
+
@C@DFFFFHHHHHJJJIJIJJJJJJJIJJJIJIJIJJJJJJJJJJJJIJJJJJJJJJIJJIJHHHHHFFFFFFEDDDDDDDDDDDDDDDACCDDEDDD39<
@5P3
CGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCG
+
C@@DFFDDHFHDDDBHIFHIHHGGGIIEHBGHGIGFEHGIIIGGIHGBEFFFEDDEEEDDDDCCDDDDDDDDDDCDDDBBDBBBDBDDDDCCCDDCCACDB
@5P4
CTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJHHHHHHFFFFDEEEEEDDDDDDDDDDDDDDDD
@5P5
AGATATTGCACGACAGACTGCACAGGGCATGGATTACTTACACGCCAAGTCAATCATCCACAGAGACCTCAAGAGTAATAATATATTTCTTCATGAAGACC
+
@B@DFFFFGHHHGJIJJJJJIJIJJJJJJJJIJJJIJJJJJJJJIJDIJFHHIIIJJJJJIHFHHFFFFFEDE@A6>ADDDDDEDEEEEEDDEEDDDDDDD
@5P6
TACAAACTGCATCAGGAGATATGCAAACATATCAGATCCGAACTACACCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATGACATCTCCTGTGACTCTC
+
CCCFFFFFHHGHHJJJIJIJJJJIIJJIIJJJJJJJJJJGIJJJJJIIIJIHJIIJJJJJJJJJIIIIIIHHFHGDEF@DEECDEEEDDDDDDCCDDDDDD
@5P7
CCAAAGTGCACGGCAAAAGATATGCTTACAAATTTGACTTCCACGGCATTGCCCAGGCTCTGCAGCCACATCCGACCGAGTCGTCCATGTACAAGTACCCT
+
@@@FFFADFHFFHJJIIGGHIIJIIIJJGIGIIJJGIEGHIJJJJIJIEHFCGGGG7@CAEA)7=;;6;6;A@<?B;,398<5<?<?::+:+>>4(4>CCD
@5P8
CAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGAC
+
@@@BDDFF>FHGDGHGGEH@EFHBHIGIIGIGGE?<GHIIG9:FDHGFGGCEDAC>FFHCHGDGACHHAAEHCCB;?BAB@;BCCCDCACCCCCCCCCC>
@5P9
CCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGG
+
@@@DBDDEHHDBFHIIIIIIIIGGHIIGGF:EEGGFHIIIIIIGEHGGHEGHCFGECGEEAEEEEHFFFFEC;CDAEEB@BBBA?@B@@BBBBCCCC3@CB
@5PA
CCTTGGTCTACCCCCGCTTTATGTTCCTGATTTACAGACAGAGACAGTGGCACAGAGAGGTTAAATGACTTGAAAAAGGTCTTATGATGTGTTGCAGAGCC
+
8;-((:6)))6@3:((((2())2.))2<><))<<:));((<=77=)0)))(8..)..)8()(89>=8).8;6((.:(3;((--;=<5003(,(,,76/(++
@5PB
TCTCTCATCGGGAAGACCTGGCTTACATGAACCACATCATGGTCTCTGTCTCCCCGCCTGAAGAGCACGCCATGCCCATTGGGAGAATAGCAGACTGT
+
@@?DFDFFDFHDHJGGEEHEHIGIJJGIBFGEDDGIJHHGGEHHJJJJBFHIIJEBGHIGFFFEBDFFDDDDDDDDDCCCDDDBB@?:ACACCCBD@A
@5PC
CTGGGCCGCGTGGTGCACATCATCCAGTCACGGGAGCCCTCCCTGAAGAATTCCAACCCCGACGAGATTGAAATCGACTTTGAGACCCTGAAGCCGTCCAC
+
CCCFFFFFHHHHHGIJJIJJJJJJJJJJJJJIJJIJJJJJJJHHHHHFFFFFFEFEEDDDDDDDBBBDDDDDDDDDDDDDDDDDBDDDDDDDDDDDDDDDD
@5PD
GTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCC
+
@@@FFFFF?DDFGJGGIJJJJEGGHIJJJJJJGIJEIICHGHGHEIIJJJAHEIJJIJJGHHHGHDCDBFC>CABDBDDDCCDDEDEDDCDDDCDDDDDDD
@5PE
TCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGG
+
CCCFFFFFHHHHHJJIJJJJIJJJJIJIGJJJJJJIJJJGGIIJJIJIDGHJGIIJGIJJJIJIIIHGHHHFFFFEDDDDDDDDDCDCDDEEEEEDDDDDD
@5PF
CGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTT
+
@@<?B@DDHHDBFG>GHGIGCHIE@DGEDEBCFGHBDGED<DGHD9FAHABFBABCCFGBEAA?@DFFCED@BDDDBACA>CCB@8&::??9ACD<CCCAC
@5PG
CAAGAAGAAAGATTGATTTTCTTAGACTCCATTAAGTCCAAATCCAAAGACTCTGTGTGGGAAAAAGAAATAGAAATACTTATAGAGGAAAATGAGGACCT
+
=@@DBDDDHFFHGIGHIIIJJJIJJEHIHJJIIJJHIJIIIJIJJJEHIHIGIIIBGDBGIGIJJJJGIIJJIFHHGFCFFFFFFFCEEEDDDDDDD@BBD
@5PH
ATCCAGTCACGGGAGCCCTCCCTGAAGAATTCCAACCCCGACGAGATTGAAATCGACTTTGAGACCCTGAAGCCGTCCACACTGCGTGAGCTGGAGCGCT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHHHFFFFFEDDDDDDDDDDDDDDDDDDDDDDDDDDDDDD<BDDDCCDDDDDDD
@5PI
GAGGCGTTGCCTGTACCGCCGTGAGTGCGTGGTAGCGGGAGGTGCGAGGTGAGCAGAAAAACATAATGTGCGGGGGGGGGCACGGCGGGGGCGAGAGGAGG
+
(((-((--(02)2))2)23((((0-0))709'())8=3'''',((,,3'',2((,3(((+(&+(+8(5(((&&0&&)&&5&&(&&&&)&&&&&&)&&((+5
@5PJ
AGGAGATCTCTGAACTTCGGCAACAGAATGATGAACTGACCACTTTGGCAGATGAAGCTCAGTCTCTGAAAGATGAGATCGACGTGCTGAGACATTCTTCT
+
CCCFFFFFHHHHHIIJJJIJJJJJJJJIIIHIJIJJJJJJJIJJJJJJJIJIIJJJJJIJJJJJJJJJJHHHHGFFFFFFDDDD@BBBDCDDDDDDDEEDD
@5PK
GAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGAC
+
@@@FFFFF?FHAFBBFFGG@FGIIIGIEDHIIGHGCHGIEGICGHHGIGIGIFECHDFFFECCEEEDDCDDD;BDDDDDDDDDDDCC>CD@CCCCDDDC9?
@5PL
CAAAGCTTTCCCCCTCCTCTGATGATTAAACAGGAACCCAGAGATTTTGCATATGACTCAGAAGTGCCTAGCTGCCACTCCATTTATATGAGGCAAGAAGG
+
@CCFFFFFHHHGHJIGIGIIIIJJGIJJIIJJIJIJJJGGJJJGIIIJJIJIIIJJIIIIHJJFGIGHIJHHHGHHFFFFFCEEEEBDFEDDCDDDDDDDD
@5PM
GGTTTCGCCGGCAGTCTCGATGATAGTATTTCTGCTGCAAGTACTTCTGATGTTCAAGATCGCCTGTCAGCTCTTGAGTCACGAGTTCAGCAACAAGA
+
@@@ADD?DD<FHHDEHE@GFFGGGIIEH@GGFHGIIIIIHC<FHHIIIIGGIIFHIIC>DG=EHFEEDEECCCCCC>;CC@;><:?BADCCCCBB<<C
@5PN
GAAGTAGGAGTACTCAGGAAAACACGACATGTGAATATCCTACTCTTCATGGGCTATTCCACAAAGCCACAACTGGCTATTGTTACCCAGTGGTGTGAGGG
+
@CCFFFFFGHHDFHGGIIIIIGIGEDEH?FAHHGIJIGHIIIIJIIIIIJIIGGEIIGIJGIIGIEHIFGHHEFFFBE>@CCEDDDCDDBDCD><ABCCBB
@5PO
TGGCAGATGAAGCTCAGTCTCTGAAAGATGAGATCGACGTGCTGAGACATTCTTCTGATAAAGTATCTAAACTAGAAGGTCAAGTAGAATCTTATAAAA
+
@CCFFFDDHHHHHJJJJJJJJJJJJJJIIJIIIIJIHIJGGHGIIGIGHIIIJJJIJIJGJIICHIIIJJIHGHHHEEF?BDEE@@CEEDDDDEDCDDD
@5PP
AGACAAGCTTGTGGATTTAAGAGGGCAAGTTAAACTCTTAGGATAGAAGAAGATCATGAAGGAGGAGGATAGAGATAGTTTGAAGGAAAGGGAAAGAAAGG
+
11+4+++2+2<2+2A+++<C<++A1)<))1?**1::1*:*****000********)))))).(.'-;'()..).)))76..(((.5((((,(((,,559((
@5PQ
CTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGC
+
CCCFFFFFHHHHGJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJHHHHFFFFFFEDEEEEEDDDDDDDDDDDDDDDDDD
@5PR
CTTTAAGCAGGAGTACCACGACCCAGTGTATGAACACAACACCATGGTTGGCAGTGCGGCCAGCCAAAGCTTTCCCCCTCCTCTGATGATTAAACAGGAAC
+
C@@FFFDFGHHHHHIIIIIJIJJIJJBGFGGGJIIJJJJGGIIHIIICHHIHGHEHIHHFDDDDDDDCDDDDDDCDCD5@DDDCDDECDEEEDCCDDDDDD
@5PS
CTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCC
+
@@@DBDDBHDHFFGGHDG+:ACGEHGIGG09BFHDH?<GHIEGIGD=B<FA@;@;8@CAEGHHAEEDEEEEC:6@A;??2?9A<?BCB9CCA@CC@CA?<B
@5PT
CCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTTATGGG
+
CCCFFFFFHGHHHIIBHDHFHGIGIIIIIIIIIIIIIIIIIIIIIIIGIIIIIIIIIGEHIHHHHHHFFDDDDDDDDDDD@D>ACDDDCDD(99?CACDDD
@5PU
TGTATGGGCAGCAGATAGTGCAAATGAAACAAGAATTAATAAGACAACACATGGCACAGATGGAGGAAATGAAAACACGGCATAAGGGAGAAATGGAGAAT
+
@CBFFFFFHHHHHJJJJJHHJJJJJJJJJJGJJJJJJJJIJJJIJJJJJJIJJJIJJJJJJJJIJJJJHHHHHHFFFFCDBDDDDDDDDDDDDCDDDDDDC
@5PV
AGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCGATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACT
+
?@@?DDBDDBD:?:AF@GDA3CAF:9<F?;FC8?@D0@6@F;(-.-5==;;DEE;=C=>CA>3?B.?;ACB=@;=;?(-(;ABB298?BB@?9<@B38<
@5PW
GACAACAAATGGAGTTGTTTTGGCTGTGGAGTTTCATCCCACAAATGAAAATACCATAATTACATGCGGTAAATCTCATATTTTCTTCTGGACCTGGAGCG
+
005=@7@7>>?)9:.:=)6))3()9@<7<11;).)=);)(07=(()))01=>;87>8>>=1=;;6=3==-:9=).6.9=9;===>7=49(;:5;737(5(&
@5PX
CCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTC
+
CCCFFFFFHGHGHHHIFGGG@FGHIGI?FBDHGIIJIJIJJJJJIIIJJJJFHHIJJJIJJJIJJHHGFFFFDECEECCCDDCDDCC>CDDDCCDDDDDDD
@5PY
CTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAG
+
CCCFFFFFHHHHHJJJJJJJJIJJJJJJJJJJJJJJJJIJJFHJJIJJJJJHAEHHHFFFFFFEEECDDDDDDDDDDDFDDDDDDDDDDDDD
@5PZ
ATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTAC
+
CCCFDFFFHHHHHIIJJJJHHGIIJJIJJJFEHGIJIIGGIIIIJJJJGIIJIJJIIJJJJIJJJJJIHHHHHFFFFFEEDDDDDDDDDDDDDEEDDDDD
@5Q0
CTGGAAAATCAAAATAAAACTCTAATAGAAGAGTTAAAAACTTTGAAGGATCTTTATTCCAATAAAAGTGTTTGATTCCTAAGAAAGAAAATATTTTTGTG
+
CCCFFFFFGHHHHJJJJJJJIIGJJJJJJJJIIJJJJIJJIIJJJJJJJJIJIJJJJJJJJJIIJIJI@FFGGIJIJIJJJHHHHHFFFFFEEDFEEEBBC
@5Q1
GTGGCAATAAATGAACTGAATATAAAATTGCAAGATACTAACTCTCAAAAGGAAAAACTCAAGGAAGAACTAGGACTAATTTTAGAAGAAAAGTGTGCTCT
+
CCCFFFFFHFDHGIJGIHEHIIJIIHGHIGHIIGI<CFHBGHIEHHJJJIDEGFIIIIHIJJGHDGGII@DGIJIHHGFHFFDBCCBCEECCD>CCCCCDC
@5Q2
CCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGG
+
CCCFFFFFGHHHHJJJJJJJJJJJJJJJJJFHIIJJIIIJIJJJJIJJJJJJJJJJJJJJIJJHHHFFFDFFEEEEEDDDDDDDDDDDDDDDDDDDDDEDD
@5Q3
GAAAAACCACAAGGACAGAGAGAAAAAAAAGAGGAATCTCATTCTAATGATCAAAGTCCACAAATTCGAGCATCACCTTCTCCCCAGCCCTCTTCACAACC
+
C@CFFFFFHHHHHJIJJJGIGIJJJJJJJJJIJJIJJJJJJJJJJJJJJJJHHHHH?DFFFFFEEEEDDDDDDDDDDDDDDDDDDDDDDDDDDDDEDDDDD
@5Q4
GATGACTCCAATGAGCATATGCTTACTGTATGGGACTGGCAGAGGAAAGCAAAAGGAGCAGAAATAAAGACAACAAATGAAGTTGTTTTGGCTGTGGAGTT
+
C@CFFFFFHHHHHJJJJIIIGIIJJJJJGIJIIJGGIIIGJJIIIIIGIJIIJJGDHGIIJIJJJJJIIHHHHHFFFFEEEECEECDDCDDCDDBCCCD4?
@5Q5
CGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCG
+
@;;=BD0<AA<:DC;BE@GF:?<G>GGBGB?BBFB4BDFF;FBEEEFF?8)?;6.6>ABA;;A;;@99?5:53?:09)&)+(()8283:4+:A::>34:>9
@5Q6
AGTTAATGAATGTGGCAATAAATGAACTGAATATAAAATTGCAAGATACTAACTCTCAAAAGGAAAAACTCAAGGAAGAACTAGGACTAATTTTAGAAGA
+
@@BFFFFFHHGHHJJJJJJJJJJIIJIIJIIJJJJJJJJJJIJJJJJJJJJJJJJJJJJJIIJJIJJIJJJJGIJIIHHHHHFFFFFEEDEEEDEDDDDD
@5Q7
CTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGC
+
@@@B+ADDBDDHDIIEE@FHEHDGFGBEGE@HHIGFBBBGECGD*9?F@F@@F@)=CCGHICGEEIGHE?CHC==BB93;3<9?>ACC:ACB?C<ABC>>>
@5Q8
CTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAAC
+
@@@DADADFDAAFEEA<C89:E;F;9860?DFEIDEGFFEIFFFFIIIFIEDFFFC<DC?6;<B3;?:,:>@8??<882<@?A@BAA>@BBBA:?A9@444
@5Q9
TCTGGAGTTTGTCACCATTGGAGGCCGGATGGAAACAAACAAGAACTGCCCTGGGCCTGTATACCTGATAATGACTCAGCGCTAGCAACATCAGCCCGA
+
;;<;??<?<)2(28)=))8116)(3=3((<((0))09((9(9==)<))9)6=?5976/(=3).).).=8;(6(9(5(---9;2',(,+(2226:/2(05
@5QA
AACCCCCCCACACCATCCAGCACGCCAGTGTCCCCACTGCATCATGCATCTCCAAACTCAACTCATACACCGAAACCTGACCGGGCCTTCCCAGCTCACCT
+
@<@DFFFFHHHFBBDHIIGI>FG?DFGFBF=CGHIIHGGIIID7A?EHHF@DB>;;AACACCCCCACA:>>@==BBBCBCCCC@<>58:>AC@>BC@>ABA
@5QB
ATGCCTCAGGAGGTCAGGGCAGCCAGAGAGCATCCCACCTGCTCCCTGCTGGAGCAAAAGGCCCCAGCAAACTTCCATATCCTGTTGCCAAGTCTGGGA
+
???:B?BDDDD:<A2<A?ABE<1CE;1:)1:C<9?DEDI;?D*?9B8.=).=((8@@DD)(6(;?1,>@AA=;3;--5;A5>((,5(>::>8(((499<
@5QC
CAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCC
+
CCCFFFFFHHHHHIJJJJIIIJJCGHHJJJJJGIJIIEIJIGIJJIJGGGGJHHHHEDFFFFFDEECEEEDDDCBD>ACDCCDBBBDDDDDDDD?CDDCCD
@5QD
CGGACATCAGCAAAGACCTGGAGAAGATGATGGTTAAGAGGAGAGACTACTTGGACCTTGCGGCGTCCACTCCATCTGACTCCCTGATTTATGACGACGGC
+
@?<1DDDDB?>B8FG+AEFEGCEEFCGCEFGEI9??DF@FEEFDFCEFFFF@FF:FFFIICFEE@>@>BA@@BABBBBB@AABB?ABA::ABA>@B<@B9<
@5QE
ACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCAC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJIJJIJJIJJJJIJJJIJJIHIIIJIJJJJJJJJJIJIJJIJIHHHHHHFFFFFEEEEEDDBBDDDDBDDDDDDDD
@5QF
CACGATTGAGTGTCAAAGAAGACCCTTCTTATGACTCAGTCAGAAGAGGAGCTTGGGGCAATAACATGAATTCTGGCCTCAACAAAAGTCCTCCCCTTGG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJIJJJJJJJJJJIJJFIJJIIJJJJJJJJJJJJJJJHHHHHHFFFFFFEEEECDDDDDDDDDDDDDDDDD
@5QG
CCGCCAGTGAGCGCGGAGACTGCTTCCACTTCGGGCGGGGGAGCCCCGGACCGAATCGGCTCTCTAGGCCGTGGAGCTTGCCGTCCCACCTCCGTCCAAAT
+
CCCFFFFDFFHHGJIJJIIIIGIIJIIIJHIJJJJJJDDDDD@BDDDDDDDDDDD@DD@DDBACCDDDCDD09@DDDDDDDDD>BBDDDDBDDB<AB<CDD
@5QH
CAGTCCGACTCATCTAGAGATGATGGAAAGTGAGTTGGCTGGGAAGCAGCATGAGATTGAAGAGCTAAACAGAGAGCTGGAAGAAATGAGGGTTACCTATG
+
B@BDDFFFHHGHHIJIJIGHIIHIIJHJJIEHIIIJIJJJIJJJJJJIIHGIJIJIIJJJJIIIHIIHHGHFFEEFDEEEEDDDDDDDDDDD<ABCDDDCC
@5QI
GAGAAATAGAGTTTAGTGCTTCAAGGGCCAGGCTGCCAGGCCATGTTGCAGCTGACCACCCACCTGCAGTGTACCGCCGGAAGCACCAGGAGCTGCAAGCC
+
???DD;D??+2CD?E+C:+ACCEB<+3AC;8:ECE8:DCD?)0?DD@B4B?DEB3.8==;;5A@;?;7=7;77;7>>8>=8?58A9><2<<>8>9A3>:22
@5QJ
CTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTT
+
CC@FFFFFHHHHGJJJJGJJFIJIJJJGIIJJJJJJCHIIIJIJJGEHJJJJIIJIEIIJIJJIGGFFDEEEDDDDDDDDDDDDDDABBACDDDCBDDD@C
@5QK
CGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCT
+
@C?DFFFFFFHHFJIIGIIJHJHGIJHIIEGEEHIIJJJGHIJJIEGFHHHIIIJGGGJIIIIGIIHCHFHHFFFFDDDDDDDDDDDDCDDCDCDDACDDA
@5QL
GAGAAAGACAAGAAGGAAAAGAAAAAAGAAAAGCACAAAAGGAAAGAGGAAGTGGAAGAGAATAAAAAAAGCAAAGCCAAGGAACCTCCTCCTAAAAAGAC
+
?@@DDDDDDAF>;FBG;EF>;F@FFB@@8DHAGHC>EHIIGBF=FH>FHHGH7=@:@;CE>CCDDEEDC@2<C>CCC@CC88?C@<?9?<9?CCCC:@@B3
@5QM
GGCCGGTGTTTGCGGACATCAGCAAAGACCTGGAGAAGATGATGGTTAAGAGGAGAGACTACTTGGACCTTGCGGCGTCCACTCCATCTGACTCCCTGATT
+
==7A<A00)2?77==A:07?A=A4:30?=A>)(==;A;AA=)7>A8.=)7.=ABA;1(;)...5.((;5,-;=6';;5;;<?;;<83:(3:8;??;====;
@5QN
CCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJICGGIJJFJJJJJIJJJIIJIJIJJJIJJJIJGGHEHFFFFFFEEEEFEDDDDDDDDDDDDDDDCDCCCEDD
@5QO
CCACGGATCCAGAAACAAGCCCACCAGCTTGTGGAACCCAACGTACGGCTCCTGGTTTACAGAGAAACCCACCAAAAAGAATAATCCTATAGCAAAGAAGG
+
CCCFFFFFHGHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHJJJIJIHHHHHEFFFFEDCEEEDDDDDDBDDDDDDDDDDDEDDDDDDEDDDDDDDDD
@5QP
GGGAAGCAGCTCGAGAGTGTCGTAGAAAGAAGAAAGAATATGTGAAATGTTTAGAAAACAGAGTGGCAGTGCTTGAAAATCAAAACAAGACATTGATTG
+
@@<DBDDBFHDBD<@:8CFHABHIGDD<FD@@;DDD*?9DGG9?8DDBDHEC@F>@FCD@C@@.>;=CCAD>7?;(.;;3@;>CC;?B95(5:;>:@>3
@5QQ
CACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCA
+
CCCFFFFFHHHHHJJJJJJJJJIJIIJJJJIIJIIIJIIJJJFHIIJFIJJJIJJJJJJIHGGHHHFFFFFFECEDCDCDDDCDDDDCDCDEDEDDDDDD
@5QR
CACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGAT
+
CC@FFFFFADFDDEGIGIJIJIIGIIJIIIJIIJJJEEIIJJJJJDHIGHJJGAGIJJJIJGFHEHFFFF@?CECDDDDDDCDECDDCDDDDDDDBDDDC@
@5QS
CTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGG
+
@@@DADBDHHFFFEGGHEHIIG?<AFHHGIIEGHIBGHGHIGHIGDGGGEEGIGIFGHHI@FCD7@DCGEFHFFFEDEEECC;;;>@C>CCCCCBCCC@C?
@5QT
CTACAAGTTTGTGTGTGATCCAGAAGCCCTTTTCTCCATGGCCTTTCCAGATAATCAGCGTCCACTGCTGAAGACAGACATGGAACGTCACATCAACGAGG
+
CCCFFFFFHHHHHHHHIJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJIJJGIJIJJJJIJDHIIIJJJJJJHGFHHFFFFFEEDCEBDDDDDDDDDDDDDD
@5QU
TGAAAACACTTGGTAGACGGGACTCGAGTGATGATTGGGAGATTCCTGATGGGCAGATTACAGTGGGACAAAGAATTGGATCTGGATCATTTGGAACAGTC
+
@B@FFFFFHGHHHHIJGEGHJHHIJJCGBGDHIGIIJJIIJEGHEBHGBFGIJIGIEGIHGEH?EHF?BBDCCCAAECCACCCDDCCCDCDDEDA>CBCC@
@5QV
GGAAGGCCTCTACAACCCCACGTCAGAGTGTGGGATTCTGTTACTCTATCCACACTGCAGATTATTGGACTTGGCACTTTTGAGCGTGGAGTAGGATGCCT
+
@@@FDBDDHFHHHIEHIIJIJEIIHBCF:?:CGHDGGDGIGGIHJIGGGHIGG@GCHIJJIGGHHGFEEEB>B@CDEAEEEC;?AB8=BB?A>CDCDDDDD
@5QW
CTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACT
+
CCCFFFFFGHHHHJJJJJJJJJJJIJJIJJJJJJJJJJJJJJIJJJJJJJIJJJIJJJIJHHHHHHFFFFFFEDDDDDDDDBDDDCDDDEDEDDDDDDDDD
@5QX
GCTCATCCCAGCAGAACAGAAGGCTGTATGTTTGAAAAGGGCCCCAGGCAGTTTTATGATGACACCTGTGTTGTCCCAGAAAAATTCGATGGAGACATCA
+
@@@DDFFFHABDHGD@+CGBFHDDDFEHGGHGDBAE?CCDGIIIAGGFEDG=BAGCHED@DCEEG?AE=ABDD?BCEECA>C?=?AC<C;CB9AABCCAC
@5QY
GAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGAC
+
B@BFFFFFFHGGHIIIHIIFHHIHIIHIIJGGIIDFHJJIJJJJJIIIIIGIFHHDFFFFEECCEEDDDDDDDDDDDDBBD@DDDDDDDDDDDDDEDDDDD
@5QZ
TTTTGAAAATATGACTGTTGGAGAAGAAAGTAAGCAAGAACAGTTGATTTTGGATCACTTACCATCTGTAACAAAGGAATCATCACTTAGAGCAACTCAAC
+
@@@FDDDDBFHGGGIIIGIIIJJIIJJJIJHGIGIGIJJIFIIHIJJJJIIIIGIGIIJIJJIIGGGIGHGGHGICHHHFDEDCDBCCECAECDDDDCCDC
@5R0
CCTAAAGGTGTATATCAAATCAGCAAACAAATCAAAGCTCATGATGGCAGTGTGTTCACACTTTGTCAGATGAGAAATGGGATGTTATTAACTGGAGGAGG
+
<BBFFDEFFHHHFIJJJJJIIIIJIIHGIIJIJJIIIJJIJJJIJJJJIJIIFGGIJJIJJJJIJIGHIIJIGIJJJHHHHHFFFFDDEEFEEEDCDD=@D
@5R1
GAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGC
+
B@@DFDDDHHHHGJJJJJJJJJJIJFIJIIJJJJIJJJIHIJJIJJGIIJJJIIDHHFBFDDBBBDDDDCDEDCDDDDDDDDDBDDDBDDDDDDDBDDDDD
@5R2
CGAAGAACCGAGAAGGGTTAAACTATATGGTACTTGCTACAGAATGTGGCCAAGGTGAAGAAAAGTCTGAGGGACCTCTAGGCTCCCAGGAATCTGAATCT
+
;;+ADD:=A<@?D@@3E+AEE93CE@BDE@:***?@9DDD@9*0??8?B(8BB8;C@@D7@3@@=)7).=?=5'5=@A35>A>A=???:?5,,::>AAA4:
@5R3
CAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCC
+
@@@DDFFFHGGHGJJJIBEF@FEGIICHJIIGGIJJHGGIJJJGEGIJJIJJJJIGHEHHHHFEDCEFFEEDECE?CC?CCDDDD<@DB@DCDC:@BABBB
@5R4
GCGGCCCCTCCGGTCCCCCCTGGACAACATGATCCGCCGCCTCTCCCCGGCTGAGAGAGCTCAGGGACCCAGGCCGCACCAGGAGAACAACCACCAGGAGT
+
@;?;;@DDDHDDAEDEHBFGGGC@FGGFHEHFGHCHA7;ABECCCCCBB6=BBA8AC<@B::>>A+8?BBB?<?B0095<A8?<222@>CBB?BBB?8AB?
@5R5
CCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATG
+
@<?DDD?=+2CD<FBGEEABBFCF<F<GFFII@FDDBCFB<?FF;?DAGBD>DA>>FG>F>A<EA7?B@?DD@DDD>BB>@@@BB????B<&<84:@@BBA
@5R6
CTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHH=BEFEDEEEDD>CCDDDDDDEEDDDDDDDDDDDDDDDEDDDD
@5R7
TTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJIJJJJJJJJJJJJJJJHHHEHFFFFFFECEEEEDDDCDDDDDDDDDDDDDDDDD
@5R8
CCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJGHHFFFFFEEDEDDDDDDDDCDDDDDDDDDDDD
@5R9
CTGGATATGCAGGTTGCAGCATTGCAGGAAGAGAAAAGTAGTTTGTTGGCAGAGAATCAGGTATTAATGGAAAGACTCAATCAATCTGATTCTATA
+
@@@FDFFFGHFHHBDGHGGGGCHIHIJJBGHEHFEGGH1?DBEIIIIJJGJJCHBFGGIII@FHIGGGIGGIIFGGGFFFFFFECCCEEEDCCCCC
@5RA
AGGATACCTGTCTCCAGATCTCAGTAAGGTACGGAGTAACTGTCCAAAAGCCATGAAGAGATTAATGGCAGAGTGCCTCAAAAAGAAAAGAGATGAGAGAC
+
C@@FFFFFHFHHHJJJJJJJJJIJJIJGIAFHIIIJDHHHGJHHIJJJHIEHJJJHIJIIHJIIJJJJJIJEFCEEHFFFFFEDDDDDDDBCCCDDDDDDD
@5RB
CTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCAC
+
CC@FFFFFHGHHHJIJJJJJIIHIIJIIJIIJJJJJJJJJJJIJJJIIIGJJJJIJGCGHIIHHHEFFFFFEEDECEDDDDABDDDDBDDDDDDCDDDDDD
@5RC
CAAGGGAAGGACGTCCTATGTACCAACGCCAGATGTCTGAGCCAAACATCCCCTTCCCACCACAAGGCTTTAAGCAGGAGTACCACGACCCAGTGTATGA
+
CCCFFFFFHHHHHJJJJJJJIIJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJHHHHFFFFEDDEEDDDDDDDDDDCCDDDDDDDDDDDDDDEEED
@5RD
TGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTT
+
=?<BB;?DFFHBBAFDDGIHBFBGHGD>FEIIIBGIIIIEHDDGGGEIIIEDHG=CCCEHFIIGGI@HCE>CB;?7;?ACCCBBBBB==5@CCCC>CCCAC
@5RE
CTGTGCGAGAGCCTCCTCACTTGGATCCAGACATTTAATGTGGATGCACCATGCCAGACCGTGGAAGATTTAACGAATGGGGTTGTGATGGCCCAGGTTCT
+
@@@DDFFFGDHFHJJJIJJJIJIIGGIIJHGGHIJJJIJJIIJIJJHIJIGHIIIJIIJJIAEFHFFFFFDEEEDDDDDDBBBB@;?CCC>?CDBAB4@CC
@5RF
GAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGAC
+
B@CFFFFFHGHHFHIJJJJIIIJJJJIIIJEGIJIIJJJJIJIJJJJIIIIFHHGGFFFFEEBEEEDDDDDDDDDDD@DDDBDDDDDDDDDDDCDEDDCDD
@5RG
ACCAGATAGCAGCTACCCCATGGACCACAGATTTCGCCGCCAGCTTTCTGAACCCTGTAACTCCTTTCCTCCTTTGCCGACGATGCCAAGGGAAGGACGTC
+
@@@FDDFDDHFHHBGHEIGHIGGEFDEHIGDGEICGIIGIJJJIGH@GI@FHIJIEHCEEH>BDBDFDDEACEDD>CD@DB=<BBBD>@ABBABBDBDBBD
@5RH
GTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGC
+
@@@FFFFFHDFHHHIHGIIJJJJJJ?FHIJJJIIGIIGCIIIIJJJJIHGJIIGIJIIJIJIHEFGFFFFBCE6>>;CDDEEDDDDDDDDDDCCCCCBDDD
@5RI
GGCTGAGCTGCGACGTCTGGCAGCCGGAGTAGGCCTGGCTAATGCCAGCTATGCAATACATACTCTTCCAACCCAAGTGGAGATTGAAAATCTTCATGCCT
+
(79?918<>)=(0(((-2@.).3=??((7-).)3)836:;90).6>)3=0:=));=??;1.3=(6((;=<(3;;;;2(((:59;52((++2(++6(+/(3+
@5RJ
GGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTC
+
:=8++ABDDD=ADA@EGEIEFA3<C<BHFCA9CD11*?:BFFIB08BFCFE>FF@CDF7=CFCFEEF2=E<BBCC@>@AA>ABBAA:>?>5::35>@A>
@5RK
CTCTATTGGGCCCCAAATTCTCACCAGTCCGTCTCCTTCAAAATCCATTCCAATTCCACAGCCCTTCCGACCAGCAGATGAAGATCATCGAAATCAATTTG
+
CCCDFFFFHFFHHDGJIIIJJJIIJIJIIIJGI@GHGIIIIIIIIJIJIIJJIIJIIGHGEGIJIJIIFGHFDCDEDDDDDDDD:AACCDDDDDDDDCDDD
@5RL
GAAAAGGAAACCTCAAGCTGAGAAAGTTGATGTGATTGCCGGCTCCTCCAAGATGAAGGGCTTCTCGTCCTCAGAGTCGGAGAGCTCCAGTGAGTCCAGCT
+
CCCFFFFFHHGHGJJJJIIIGIEJJJEHHIJICGHIJJJIIJJJJJJIIIJJIJIIJGGIJGHHHHFFFFDEEEDC>CD@B@BBDDDDDDCCDDDDDDDDD
@5RM
CAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCT
+
CCCFFFADHABFHGEGIIIIGIIII?BHDHBHIII?FGFGCEGIGIEIIIIIGGIGIGIEDGEHFHFFDFDDAC6;@>@ACDCDD@<B5<?CCCDDDDBD
@5RN
CTGGAAATGATGCCTATGTTGACCTTGATCGTCAGCTGAAGAAAACTACAGAGGAACTAAATGAAGCTTTGTCAGCAAAGGAAGAAATTGCTCAAAGATGC
+
CCCFFFFFHHGHHJJJJJJJIJJJJJJJJJJJJJJJIJJJJJJJJJIJJJJIJJJJJJIJJJJJJJIJJJJIJJHHHHHHFFFEEEEDEEDDDDDDDDDCD
@5RO
CAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCC
+
@@@FFDDBFBBHHGGGHDHIIIIAC<CEEH@@7F=FHGGGGIDAFCADF8DF?=CH8BFHIG@DEE@>EEHHHB3?B@ACAA>;C@CDDCACCCCACC9??
@5RP
TGGGAATTCCCTCGGAAGAACTTGGTTCTTGGAAAAACTCTAGGAGAAGGCGAATTTGGAAAAGTGGTCAAGGCAACGGCCTTCCATCTGAAAGGCAGAGC
+
@C@FFFFFHFHHFGIAGGGIGEHGGJJGHJEGFAFGHBIEGGGJICDFBBB@FHIFIHHAHHEF@DFD@C@CEABDDB??B@CCAC:@CCCDDCBDBD?BC
@5RQ
CAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCAC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJIJJJJJJIJJJJJJJJJJJJIJIJJJJIEHHHHHHHHDFFFFFDECCDDDDDDDDDDDDDDDDDDDDDDD
@5RR
GTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTAC
+
===D:?D:AD<DD3CEA+<CDFA?322+<EE::DD@)B;?B?BD?8B28.8(/8=:777)=)77A;?;@)??(;(...(553,5=??(5992(8833+4:A
@5RS
GTCTGAGACTCCTGCTCAGTGTAGCATTAAGCAGGAACGAATTTTATTTACACCTCCAGAGGGCCCAGTGCCGAGTTACGCTTCCTCGACGCCACTTTATG
+
<??BB>D=DDDDD:+<A<+3<,<FAC<EE+CC9?)))11C10?D**?*9*0**9??8)8)((-;ADDD773A@4'(5-;?3>?':A>88>55-5;A>(++4
@5RT
TCCTCCTTTGCCGACGATGCCAAGGGAAGGACGTCCTATGTACCAACGCCAGATGTCTGAGCCAAACATCCCCTTCCCACCACAAGGCTTTAAGCAGGAGT
+
CCCFFFFFHHFHHJJIJJIJJJJJIJIJIIIJJDHHJIIIHHIIIJJGJHHFFFFFEEECEEDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDD?
@5RU
CCAAAGGCGAAGGCCAAGGCCAAGGCCAAGGATAAAACCAAGGCCCAGGTTGCAGCCCCAGCTTCAGTTCCAGATCAGGCTCCAAAACGTACCGAGGCCCC
+
;(--@711(0<58>(8.(1((=;(3((((6;6)0..0)0<=161659((88>;;;..,,3306;34;(-7;26(,3,26(5(+63:(+&(22+&)005865
@5RV
CGGATGTAATCAACACCGCTTTGCCGATAGAATATGGTCCACTTGTGGAAGAGGAAGAGAAAGTGCCTGTGAGGCCCAAGGACCCTGAGGGGGTTCCTCCT
+
==?+B82A:<,<A:<;:EEGAF?EG@F@G<<<999?B949/9??=8=CB3=FEC6CDFE>A?EDB>?;B6;A@;?;;5,51,59??9(3200005+:@:99
@5RW
GGCAGGGTGGATCCTGATCTGTCCAAGCCTAAAAACCTTGCTCCTTTACAAGAGAGTCAGGAGTCTTACACAACTGGGACTCCCAAAGCAACATCTTCTC
+
??@DDDD<DDDHDHIEGGIJJIIJIJIGIIEGIIIGFGIGG@HIGFEF>GHCAHGHHGHIIEGI;AEHHCEDF?@AC@;ABCDDDDDD<>CADCDDCCC(
@5RX
CAAAACTTTTGTAGCAGAAACATTGGAAATGGGTGAGGTTGTTGAAAAGGATACAACAGAACTCATGGAAAAACTTGAGGTAACCAAGCGAGAGAAATT
+
@CCFFFFFHHH?FIJJIJJJJJJJIJJIIIIIJ?FHIJIIIJJJJJJJJJIJJJJJJJJIIJJJJJJJIJHHHHFFFFFD;@CCEDDBBDDDDD?CDDD
@5RY
CTGATGTTTTGAGGCGTCTTGCAATCTCTGAAGATCATGTGGCCTCAGTGAAAAAATCAGTCTCAAGTAAAGGCCAACCAAGCCCTCGAGCAGTTATTCCC
+
BCCFFFDFHHHHHJJJJJJJJIJJJJJJJJJJJJJJIJJIJJJJJJJIHJIJIJIIJJJHHHHHHFFEFFFFEDDDDDDDDDDDDDDDDDDDDDDDEDDED
@5RZ
GCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCC
+
@@@FFFFFDFHGGEGFHHGEIJJCFFIJJH@DHGIIIIJGIJBDEHJJJIIGIIJGIGIJIIIGHHEEEFDFFDEEEEDDDDBBCDDDDC5:ACDDCECCC
@5S0
CTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCT
+
CCCFFFFDHHHGDFHAGHGIIGAGDEEHGHBEFFDFEGH@?FFDBD?DEHIE;BFC;@GDHIICHIEEHHH=BBA3;BC3;@CCCEAD:>CCCCCCCCCCC
@5S1
CAGATAGCAGCTACCCCATGGACCACAGATTTCGCCGCCAGCTTTCTGAACCCTGTAACTCCTTTCCTCCTTTGCCGACGATGCCAAGGGAAGGACGTCCT
+
@C@FFFDDHHDHHGGHGIDGIHHIJJJICFHCFGHJEBDEGGBGHIGFHGDEGIFHHHHAHACFFDCDEEEDEC@CB>?@>???@CDDD??8<?ABB9@?B
@5S2
ACACTGCGTGAGCTGGAGCGCTATGTCACCTCCTGTTTGCGGAAGAAAAGGAAACCTCAAGCTGAGAAAGTTGATGTGATTGCCGGCTCCTCCAAGATGA
+
???DA2=)@@;ADEAED@EF<=EAD1?DDCDA@DEDCDEA:D6ADCDAD==@C?D@ADADDAAA>=;5>AAA>ABA>ADDAAA>?>>>>?><A?AA>A>A
@5S3
TGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTAC
+
@@;DDDDBFFFADF@FAH>CEFGHIII@AFDGBBDFCHE?BDGHIIC)BG@C)=CCCCCEHHHHEDEEDACACCCCADCCC@BBBBBBB@@C9A(4<:CC
@5S4
AGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACC
+
@C@DDDDDHHHHF?GIBGIEGGHIGCECHDHIIIGIIGEHIIGGGHHFGIIIEEE>C=F@HICHGHECHEHFD@DEEEDDDDCDDCDDD?A3>>?AA9<AA
@5S5
TGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTC
+
@@@AFDFFBDDHDBFFBDECEEGIGE@@HGHEDAB??@GGDEHEGDBGEDFGGIIGAGG=FFHEA@AHF>CE>>9A>CDCAD>C;AD@AAC@AA@CCAA>C
@5S6
TGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTAT
+
CCCFFFFFHHGHGJJIJEIJJJJJJJJJJJJJJJJIIJJJIJEHJJJJJIJIJJIJJJJGJGHHFFFECEEECCACDDDDD<CDBDD?CDBDDDDD:@CD
@5S7
ATGAAATGAGTCAAAAGATAGAAACCATGCAGTTTGAAAAGGACAATTTGATAACTAAGCAGAATCAATTAATTTTGGAAATTTCAAAGCTAAAAGATTT
+
@C@FFFFFDFFHGJJJJJJJIIJIIIGIJJJJJIJJGIJGIIGIGGIIJIIGIJEEGIGGGIIIIJIJJJJJJJJJIHHHGHDFFFFFEDEEDEDDDDCC
@5S8
GAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGAC
+
@@@DDFFDADHHAHIIJJIIIJJJJDIIJBHIGIDGGIGIGGICHIIJJJIIGHFFFFBEECCEEEDDCCDDBDDD>?BDDDDDDDDCDBACCCCC@CCDD
@5S9
AGGGAGTCAGGTGCATTGAGAATTGTGGTTTCAGACTGGTTGCAGAATTTGCAGATTAGACAAGAAATTTTCACTTTTTGGAAAGTTTGCCACAGCTTTAT
+
11+44)=+2:++++2<AA<+A,<33AFE<?)*::**1111:0)*000?*0?0/**?8).))..(8).=4=;).7=).=?@?)(((;6.(--(((5,>((,,
@5SA
CGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCT
+
CCCFFFFFHHHHHJJJJJJJJJHJJJJJJJJHIIJIJJJGIJJJJJJJJJJJJJJHJJJJJJJJJJHHHHHHFFFFDDDDDDDDDDDDDDDDDDDDDDDDD
@5SB
AGCCAAGCTTGCCCAGTTTCGACAAAGAAAAGCTCAGTCGGATGGGCAGAGTCCTTCCAAGAAGCAGAAAAAAAAGAGAAAAACGTCAAGCAGTAAACATG
+
=?8+4A:+=D;?D3AED<FF@BCFEE;EE@@?8CDDE4:)6(/7;=CD/C=..=47@).7...;?DDDAAAA8;39>><>>><99(+2-448<(+::>::4
@5SC
TATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTAC
+
CCCFFFFFHGHFHIJJJJJJJJJJJJJJJJJGHIJJJJJJJJJIIJJJJJJJJJJJJJIIJJJJJJJJHHHHHFFFFFEEEDDDDDDDDDDDDDEEDDDDD
@5SD
CCTCCTCCATCAGTGACCTGAAGGAGGGGCCGCGGAAAAACATCACCCTCATTCGGGGTCTGGGCCATGGCGCCTTTGGGGAGGTGTATGAAGGCCAGGTG
+
;+:<<<==@+ABB<?++23<A=BB32?)??=?==AAA@>A@=@@>>@@==;;>=?=;===3838(88+8;(5&0)5=8?==;;;+883;;?=?=9;<<;3;
@5SE
GCAAGCCCTAGATAGCCCCAGAGGGATGCACAGGGATGGGAACACTCTGCCATCCCCCAGCAGCTGGGACCTGCAGCCAGAACTTGCAGCTCCACAGGGA
+
;;?DDABDA;F<:AFDFEBEEGEEF?BEBFFIEEI<;@6?;80?BC)8.=8C;@8@;A=EEFD?7?BC;>@?;;?>><@B9A?:@:>3>@>:34<>?BB8
@5SF
CTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGC
+
@@@FDFFFHFDDHGCHJGIIJJGFHIJJIIJIIJJGGIJIIFHCHFGIICIIJFGHGGDGIGIHIJIIIHFEEHFFFFFEB@CDDDDDDDDDDDBDDDDD
@5SG
ATTCTGATGCAGCAGAGCTTGGAAGGATGCTTCAGCTCATCTTAGGCTGTGCTGTGAACTGTGAACAGAAGCAAGAGTACATCCAAGCCATTATGATGATG
+
@@@FFFFFHFHFGHEHGIIIIIGJIJHGIIJIJJIJEIIGIIJIIJGIJIGHIGGGEGHJJHHGGGIJIIJIGJGEH=AHBDFFFFEDDEDDCEDCDCCFD
@5SH
GGAAAAGGAGACAATCATTGAAGAATTAAACACAAAAATAATAGAAGAAGAAAAGAAAACTCTTGAGCTAAAGGATAAATTAACAACTGCTGATAAATTAC
+
@@@FFFFFHGFHHIJJJIJIIJJHIJJIHJJJJJJJJJJIIGIJIJJJJJJJJJJJJJJJJIJJJGJJJJHHHGFGFFFFFFDEEEDEDDDDDDDDDEEDC
@5SI
GTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACA
+
;@@;?DDDHFHHHDH<DGHIIIIA?<G@CDFB3:*???B*??<?FGH9DHEGG98=FGC@GHHIIICE>7=2;@<;;;@;=;1;?<?BCC>C@@>:@CC
@5SJ
CTTCAGCTCTGGCAGTTTTTGGTAGCTCTTCTGGATGACCCTTCAAATTCTCATTTTATTGCCTGGACTGGTCGAGGCATGGAATTTAAACTGATTGAGCC
+
CCCFFFFFHHHHHJJGIJJJJIHHIIIJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJIGIHHFFDDEDDDDDDDDEDDDDDDDDDDDD
@5SK
GAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACT
+
BBBFFFFFHHHHHJJJJJJJJIJJJJJJJIJJJJJJJIJJIJJJJJJJJJJJJJJJJIJJIJHHHHHHFFFFFECDEEDDDDDDDDDDDDBDDDDDDDDD
@5SL
AAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCAC
+
C@@FFFFFAAFHDGIIIIEGIIIHHHJJIBEDGHIIIGGIJJJJJDGEBGEEACHDFEE?>CEECACDDBDBDDBDDDBDDDDDDDDCCCCCDDDDDDDDD
@5SM
GGCGCTTGTGAGGGGATGAAACGTGGGGTCTCAGAGAAGGACCAGCGAGAGGTGCTTTCCGAGGACGCCGTCCTGAAGCCGCCCCTCCTCCGACAGGTGAT
+
((-(-(--()))(:((2(2)).((1((0(-<13)61)0777.6=1(--'',(..(.(.:8(',3'3'&50)006(+226(&&))&()2((+&)&&&+5((+
@5SN
ATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCA
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJIIJJJJJJJJJJJHHFFFFDDEEDDDDDDDDDDDDDDDDDDDDDDDDDDDDDEDDDD
@5SO
CGTTGGGGCATTCAGAAAAACAGGCCAGCTATGAACTATGATAAACTTAGCCGTTCACTCCGCTATTACTATGAGAAAGGAATTATGCAAAAGGTGGCTGG
+
BCCFDFFFHHHGHJJJJJJJJJJJJJIJIJJJJJJJJJJJJIJJJIJJJIIIJHIIJJIIJIHFFEDFFFFEEEEDEDCDDDDDDDDDEDDCDD>ABDDDD
@5SP
GTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTAT
+
@@@FFFFFHHHHHJJJJJJJIIJJJJJJJJJJJJGIJIJJJJJJJJJJJJJJJJJJHHGHFFFFFEEDEEEDDDDDDDDDDCDDDDBDBDDDDDDEDDDCC
@5SQ
ACCAGATAGCAGCTACCCCATGGACCACAGATTTCGCCGCCAGCTTTCTGAACCCTGTAACTCCTTTCCTCCTTTGCCGACGATGCCAAGGGAAGGACGTC
+
CCCFFFFFHHGHHJJJJJJJIJJJJJJJJJJIJJJJJJJIJJJJJJIJJJJJJJJHHHHGHFFFFFFEEEEEEDDDDDDBDDDDDDDDDDDDDDDDDDCDD
@5SR
CAACTATGATGACATCAGAACGGAACTGCCTCCTGAGAAGCTCAAACTGGAGTGGGCATATGGTTATCGAGGAAAGGACTGTAGAGCTAATGTTTACCTTC
+
1?@BDDDD>C?BFGEEGG@FAEGGHB><?CDHDACHB?GHDAFBHGB>F3/9/=CCA;CHGHI7CG@7CEAD>DECCAB?A3;((5(:A:>@@D;ACCCCC
@5SS
GGAGTCATGCTTATATGGAGCAAAACTACTGTAGAGCCCACACCTGGGAAAGGACCTAAAGGTGTATATCAAATCAGCAAACAAATCAAAGCTCATGATGG
+
@@@D?DDDBHHHFGHIEGGEHEHDFHGIGIEAFGGGHIGIGIIGIGIICFEHIIIIIGGIII8@=@GHDGHHEEFFEEDFFEECEECCCCCCCCCCCCCCC
@5ST
GAAAAGGAAACCTCAAGCTGAGAAAGTTGATGTGATTGCCGGCTCCTCCAAGATGAAGGGCTTCTCGTCCTCAGAGTCGGAGAGCTCCAGTGAGTCCAGCT
+
<;@?D>?AAFHF?<?@>CGGEHEH>GAEDC4?1:EEGBEGB0??D?DFHIIGIGA@FAEH=EEHA=B?BD5@C@@C-;>=BBBBBCCCCC:@AC:>@CCA:
@5SU
AGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAAC
+
CCBFFFFFHHHHHJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJHHHGHHFFFFFFEEEEDEDDDDDCDDDDDDDDDDDD
@5SV
CCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAAC
+
CCCFFFFFGGGGHJIJJJIJJJJJJJJJJJJJJIJJJJJJJJJJIJJEIJIJJIJJJIJIIIJJJHHHFDEFEFEEDEECEDDDDDDDCCCCDDDCBDDC
@5SW
GTCGTCCATGTACAAGTACCCTTCTGACATCTCCTACATGCCTTCCTACCATGCCCACCAGCAGAAGGTGAACTTTGTCCCTCCCCATCCATCCTCCATGC
+
@C@FDFFFHAFFHGGGIHIJJIIJIJGHIIJJIGDHIIIIGHIJIDHGIGI<DGHHIEHIGIIIJJDH=@HGFFEHHHHDDFFDDD@CCBCCDDDDDCA@C
@5SX
GTTCTGTCTTTGATGAAGACAATACTTTTGTAGCAGAAACATTGGAATTGGGTGAGGTTGTTGAAAAGGATACAACAGAACTTATGGAAAAACTTGCGGT
+
+1122222,227C7ABB<7AA;+++3,,@=222221)@B@*1?=7*0*00?A))((0/.)'9(.>4).-()..=A7A>37);(.56((;5,(9>9>(','
@5SY
GGAAACCTCAAGCTGAGAAAGTTGATGTGATTGCCGGCTCCTCCAAGATGAAGGGCTTCTCGTCCTCAGAGGCGGAGAGCTCCAGTGAGTCCAGCTCCTCT
+
@<?D?BBAB<CD?EDBFGI>G?FHHGIHH>99CGEFEGG>GC9BBFF??CEEE;@CG?HG@EHH;57?C@7(5>BB<BBBCCCCC:::4:@>A@CCCC9?3
@5SZ
TGTGGCTGTCAGTATTTGGAGGAAAACCACTTCATCCACCGAGACATTGCTGCCAGAAACTGCCTCTTGACCTGTCCAGGCCCTGGAAGAGTGGCCA
+
@@@DDDFFFCBFA<EGHIEHIIIDEHGGBEGIGIIHIGHBF<DD<GGHE@<=8CGIIDGDGCEEH7=EEHFFFB;@@A>C?BBB??AA3,<,:?719
@5T0
TGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGAT
+
@;@BD>DA<DDBF@FFBFA9F:3CFI@E>GGICFGD<D>FGEF9FFFEEBEFIIA=CAEAE?C>?;6;?@;6>BBB9?23;@@99?B?A<+3(:@(++3@
@5T1
CTAAAACAGACACATGGTCCTTTGGAGTGCTGCTATGGGAAATCTTTTCTCTTGGATATATGCCATACCCCAGCAAAAGCAACCAGGAAGTTCTGGAGTTT
+
@@@DDDDDFDDDHGIGIC?+AEHIIFFFHGIIIGGHIFGGIIFABCEH<BFGDGIG>FHEEH<CHIIGIG=@1=CEECDBDEEAB==?BBCC>>A@CBCCC
@5T2
GAAATAGTTTATTTCATTGCATCAGTAGTAGTACTATTTAATTATGAGGAGAGAACTCAGCGACACTACCTGGGCCATACAGACTGTGTGAAATGCCTTGC
+
CCCFFFFDHGHGHJJJJIJJJJJJJHIJIIJJJGHIJJIJJJJJJJJJIIIIJJIHGIIIJJJIIIIJGIJJHHHGEFFFEEEEEECCCDCEDCCCDDDDD
@5T3
CGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGGAGGGCTACAGTGCTTACACCG
+
CCCFF@@DDHHFDBGIIIIGHIIIIIGIIIIIFEFDG@FEBHIIHFHHFFFFEECCECECCCDCCCCABCCCCCC@BBBBCB<BBCBCCCDCCDCCCCCCB
@5T4
CAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCG
+
CCCFFFFFHHHGGJIHJIJJJJJIGJJIJIJFHJJJJIIIJJJIIIIJJJJJIHJJJGJIJIJJJJFGHHFFFFFEEDEEDDDDDDDDDBCDCDCDEEDED
@5T5
GTTGAAAATACATACTCCTGTTAGCCAAGAAGAAAGATTGATTTTCTTAGACTCCATTAAGTCCAAATCCAAAGACTCTGTGTGGGAAAAAGAAATAGAA
+
?=?DDDDBDHGHFIIIIIIGIIIIIGIIIIIIEHIICFGEGIIIIIEIHCGHGIIIIIIIIFGGGHHIGGGIIGHIEIHHHH?EEFFCDEEDDDDDDDDD
@5T6
CAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJIGJJJJJJJJJJJJJJJJIJFHHJGJJJJJJJJJJJHHHHFFFFFEEEEEEDDDDDDDDDDDDDDDDDDDD
@5T7
CGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCG
+
@@CBDFDFHHHGHGIJJGIJGHIGIIJIGIGIJJIGHGGIIIIIJHHGFFFFECBDEEEDDDEDDDDDDDDDCDD@DBBDDDDBDBBDDC>CCDDCDDDDD
@5T8
CTGTGATTCCTGAATCTACAATAATGAGAACTCTACATAGTGGAGAAATAACCAGTCATGAGCAGGGCTTCTCTGTGGAACTGGAAAGTGAAATTTCAACC
+
@@@DDDFDAF?FBHGGE@EHGIFGIGBHEGIEIEHGHHEG:CCFH@DGHGCGHIIGHBF@DFFDHDIHGHIEHHA>EHCEHFFBDDDE6>CDCACDDDD@?
@5T9
GAGGACTTTCGCTATCGATCTCCTCATTCAGGTGATGTGCTCTATGAACTCCTTCAGCATATTCTGAAGCAGAGGAAACCTCGGATTCTTTTTTCACCATT
+
BBCFFFFFHHHHHJJJJJIJJIIIJJJJIJJJCGHIJIJIJJJJIJJJJJJJJJJJJIJJJJJJJJJJJJJJJJHHHHFDFFDDDDDDDEDDDDCDCCDDD
@5TA
CGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTT
+
@<@DDDDDDFDDDGHB>?4EG4EEHHGCFE?F>FBC9CFDHIDBFGCHIII<??BFGHIEAEB=?7@D@CCABBB?BCCACC?86?@@A9<+:9?BCCCC>
@5TB
CTGGTTTCCAAACAGAGGATTTTAGTCTATATGCTTGTGCTTCTCCAAAAACACCCATCCAGGCAGGGGGATATGGAGAATTTGCAGCCTTCAAGTAGCC
+
<@@FDFFFGHHDHGHIII>FHIIIIIIIIIBFEHGGCGGDHIIIFIGIIBGHGIIIBEHIIIFIIEGHHF=BDCDCCDDDDDDD>5>C?ADCDD@CCCCC
@5TC
CGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCG
+
@@CFDDDDHBHBFIJHIGIEEHGBHHGJGEC?GHGGC<FHGGBGIGHEFFEFEC;CEEECDDDCDDCB?CCDDDCBDDBDDDBBBAA?CCBACDDDCCCDB
@5TD
GAAGAATTTGGTGTTGATGATTCTTATTCTGAACAAGGAGCACAAGACAGTCCGACTCATCTAGAGATGATGGAAAGTGAGTTGGCTGGGAAGCAGCATG
+
@@@DBDDBHHFADEFHFFGHGIGHGHIJGIIIHIIJJGIIIJJJJIIEEHIJJGIGGEIG>CHEIG@DHEHHHEFFF;?CECEEDDDBB@BDBBDDDDDD
@5TE
GGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTT
+
@@@DBDDFHHFHFHJIJJGGIEECHEGHHIJJJJJIJGIJJJJIJJFJIGIIIGIJJEEHIFHHGHGFCFCEDCBDBBDDDDDD?@DCCDDDDDD>>BBD
@5TF
GCTATTACTATGAGAAAGGAATTATGCAAAAGGTGGCTGGAGAGAGATATGTCTACAAGTTTGTGTGTGATCCAGAAGCCCTTTTCTCCATGGCCTTTCC
+
CCCFFFFFHHHHHJJJJJJIJJJJJJJJJJJJJFHIJJJJIJIJJJIJJJJJJJJJJJIJJJJHIHHEHIIJHHGHHFFFFFEEEEEEDDDDDDDDDDDD
@5TG
GAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGAC
+
@<@FFDEAHDHHFGIDHIJJIIGJJIJJJIHHCHGIHIGHGJIIIIC<EBEGEHHGE@BDECCEEEDCDDDD?=@B9ABDDDBDDDDDCA:AC@CCD@<9<
@5TH
CAGCCAGGAGGGTCCTCCAGGCCTTCCGCCTCAGCCTCCACCACCAGTTGCTCAACTGGTCCCCATTGTGCCCCTGGAAAAAGCTTGGCCAGGGCCACATG
+
@??BBBBBB<C?<2CCCEBE32:EFB:?F?:@?B9)09?9??FB;8@8=F777@E=@=?.7?=;7?BC6(666=??;5>59@:2:3>@A>9?158828@4@
@5TI
CAGATGACCCCCAATTGAAAAGAGAAATAAGGTTAATGAAAAACAGAGAAGCTGCTCGAGAATGTCGCAGAAAGAAGAAAGAATATGTGAAATGCCTGGA
+
BC@FDFFFHGHHHJJJJIGDHIJJDIJJJJJIHIHGIJIJJJJJJIJJJJJGIIGIJIJIIGJGFHHHFFCECEEBCDCDCCB@CDDDFEEDDDDDDDDD
@5TJ
CTGAGGTTTGCCAGCAGCCAGTGTACATTCCGAAGAAGGCAGCCTCCAAGACACGGGCCCCCCGCCGGCGTCAGCGTAAAGCCCAGAGACCTCCTGCTCCT
+
:=77A=A;C;@@4AAA;+33?CA2<><C=>AA4??0?353?5))==AB3)..==6<6--='','720)05))5;?5;9<8:888(+8(89;8=<(+8(8?3
@5TK
ACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCT
+
@@;;DBDDHDHDA<EF?GHIGIIID>FHEGGIIGBGHCGGIIEHGHCHEG<CCAF=GGHIHHDDDEECCCCABBCBCB:>@:ADACC,:>@C@@<ACCCB3
@5TL
CGACCATCACCAGCTGAAAAGTCACATAATTCTTGGGAAAATTCAGATGATAGCCGTAATAAATTGTCGAAAATACCTTCAACACCCAAATTAATACCAA
+
@BCFFFFFHHGHHJIJJJJJJIJGIJIIIGJIJJIJJHIIIJJIJIFHIIJJJJJJIJIJJJJJJJIJJJHHFFFFFFEEDDCEDDDDDDDDDDEECDDD
@5TM
CCACTCTTTCCCCAAATTCTCGCCTCTATTGAGCTGCTGGCCCGCTCATTGCCAAAAATTCACCGCAGTGCATCAGAACCCTCCTTGAATCGGGCTGGTTT
+
C@@FFFDFHDHHHJJJJJJJEGIGEHIGJGIGHIIIB@FEHHEGGGGIIIGIJJJIJIGGEEHGFFCDBCCDDCDDCDCB=BBDDC@ACCDDDDD@BDCDD
@5TN
CTTGATTAGAGACCAAGGATTTCGTGGTGATGGAGGATCAACCACAGGTTTGTCTGCTACCCCCCCTGCCTCATTACCTGGCTCACTAACTAACGTGAA
+
CC@FDEFFHHHHHJIDHIHGJJJIIJJJJJJJJGGJIJJIJIHJIEFCEHIJIBGIIJJEHJGEEDBDDBDDDDDCCDCCB?ACDDDDDACDDCD<AAB
@5TO
GATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGC
+
CCCFFFFFFHHHHJIIGGHIJJJJIJJJIGIJJJJJJJJJIJJJIIIIJJECHIJIHHFFFFDDDCDDCDDDDDDDDEDDDDDDDDDDBDDDDDDDDDDD
@5TP
TTCCTGGCTCATCCCAGCAGAACAGAAGGCTGTATGTTTGAAAAGGGCCCCAGGCAGTTTTATGATGACACCTGTGTTGTCCCAGAAAAATTCGATGG
+
@<@BDD8;A<DFDEFFFD?F3CCEFEI+88*?1:19?D@D>FCFE7D@BFFFCBE9C7=DEFEIEE33A>BDBB@>;ABCA@AA>?>AB@BB:(((,)
@5TQ
GGGAAAGCGAGAGGGAGACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGG
+
@@@FFFFDHDDCFGHEFEGGIJJIDHEBGEHGI@FHHIADE;CEFFFBCACCCDCD?B?BDDDDD>BDDDDCDDDDCDDCCCDCCD@CCDDDDBDDBDDBB
@5TR
CTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTT
+
@@?DDBBDHFHHDIFE@ECFHHI@@3CE1?FHICDEEHI@>@FEHEGIIGGHIGEDF;CE@@E@GHIFFAEDFBD@C@ACCCAA@>@C?C<BBB@B@BC>:
@5TS
GTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTAC
+
B@@FFFFFHHHHGEGIIHJFHIIGIGIJIJJIIJJDHGGHIIIIIIGHIFGJGHGGHGHGGCEHHHHHFDFFDDECEEDDDCD?BAABCDDDCDBDD@DDD
@5TT
GACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACAC
+
7==<=8AA0<C;A;A+?=1?AA<A4;?9A>A=;=A>BA==;<;A<5=;==<=@5;;?;5;==??==??=98==399(09;;5<=;;;;99??;:7=8:???
@5TU
GTAACAAAGGAATCATCACTTAGAGCAACTCAACCAAGTGAAAATGATAAACTTCAGAAAGAACTCAATGTACTTAAATCAGAACAGAATGATTTAAGGCT
+
BB@FFFFFHHHHHJJJJJJJJJJJJJIJJJJJJJJJJJGHJJJJJJJIJJJJJJJJJIJJJJJJJJJJJJHJJJJJJHHHHHHFFFFFECEEEEEDEDDDD
@5TV
CCATCAACCTCTCTCATCGGGAAGACCTGGCTTACATGAACCACATCATGGTCTCTGTCTCCCCGCCTGAAGAGCACGCCATGCCCATTGGGAGAATAGC
+
;?:DD?:22<A?<?EA,23)3CFD3:9*:?8DDAED><?D<???BD3D?88./.=C7A==A8)5A<49?@;6@A>35988=<(,5,++>>A?(<5(>4+(
@5TW
CTTCACAATGCAAATTAGTTTCTTGCAAGAGAAAATTAAAGTATATGAAATGGAACAAGATAAAAAAGTAGAAAACTCAAATAAAGAAGAAATACAGGAA
+
CCCFFFFFHGHHHIIJJJIIJJIJJJJJJIJHIJIJJJIJJDGIHIIJJJGIJIJJJJIIJJJJJIJJDDGGJJHHHHHFFEFFFEEDEEDDDDDDDDDD
@5TX
CCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJGHIJJJJJJIJJJJIHHHHFFFFFFEEEEDDDDCDDDEDDDDDDDEDDDDDDDACDDDDDD
@5TY
GGAAAGTGGCATGGTGATGTGGCAGTGAAAATGTTGAATGTGACAGCACCTACACCTCAGCAGTTACAAGCCTTCAAAAATGAAGTAGGAGTACTCAGGA
+
BC@FFDDDHHHHGIAFHIJEHGIJJGGIJJJJJGIIGIIIGIHHGGJCHJGIIFJJJJJJJHIEHHJJJCHJIHGHHHHFFFFFE;ACECD?CDDDCDDC
@5TZ
CAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCA
+
CCCFFFFFHHHHHJJJJJHIJJJJJJJIJJIJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJHHHHFFDDEDEDDDDDDDDDDDDDDDDDDDDD
@5U0
TGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGC
+
@@@FDDFFHHHFFGJGEGIIJIJIEGIIJGHIIGEIGHGGGEFHIIGIJIIIJGJGDAGIGGIIGH??CHFFFDFDFCEACCCDDCDDDCDDCDDDDBBD
@5U1
CCTGGACAACATGATCCGCCGCCTCTCCCCGGCTGAGAGAGCTCAGGGACCCAGGCCGCACCAGGAGAACAACCACCAGGAGTCCTACCCTCTGTCAGTGT
+
@@CFFFFFGHHHFJIJJIIGHIIIJJJJJJGIIJJJJJJJJJFIJHGGHFFFDDCDDDDDDDDDDDDDDDDDDDDDDDDDBD9?CDCDDDCDCCCCDD:@>
@5U2
ATTCTTCTGATAAAGTATCTAAACTAGAAGGTCAAGTAGAATCTTATAAAAAGAAGCTAGAAGACCTTGGTGATTTAAGGCGGCAGGTTAAACTCTTAGA
+
CCCFFFFFHHHHHJJFFHIIFJJJJJIIJJJFHIJIFHIJJJJJIJJJJJJHIJJJJJJJJJJIJJJJIJBGHIJJJJJIGHDDDDDDDDDDDCDDDDDD
@5U3
GCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGT
+
CCCFFFFFHHHGHGHIFHIHIHGIJHIIIJJJIGIGJJJJIIJJIJJJIJJJJIJJJJJJJEHJJJJJHHHFFDECDEDDCCDDDDDDDDDDDDDDDDDD@
@5U4
ATTTAAAATATTTATTGTCTAAAAGTCCGGGTGTATTCAAAGGGGATTGCTCTGTAATCTGTTTTACTACATGATGATGATCATCAATAGTACTTTATAT
+
807>())22))2))2)).98686.).))(((-:=)=)2):)))(((-9.)./))./.33))8=)))::8))..88)).)))..(((.(((6((((-(((-
@5U5
TGAAGACAAAACTTTTGTAGCAGAAACATTGGAAATGGGTGAGGTTGTTGAAAAGGATACAACAGAACTCATGGAAAAACTTGAG
+
@@@D?DFDFHHFFHIIEGIGBHGHHEHGHCFGCHGGGGI;DFGGIIIEF>DFGFGBDCEDCHGGHGGHHAAHEHFFFFB<C>@CC
@5U6
GCAAAGCTCTCCTGCTGCTGACCAAAGAGGACTTTCGCTATCGATCTCCTCATTCAGGTGATGTGCTCTATGAACTCCTTCAGCATATTCTGAAGCAGAGG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJFHHIJGIJJJHHHHHHHFFFFFFEEDEEEDEEFEEDDDDDDBD
@5U7
TTCTTCAGTATGCACAGACCTCTGATGGACAGCAGATACTTGTGCCCAGCAATCAGGTGGTCGTACAAACTGCATCAGGAGATATGCAAACATATC
+
CCCFFFFFHHFFHJJIIIIJIEHJJJJIJIIJJJIJJJIIJJJGIJJJJJIIJIHIJ?FHA>HHEHIJJHHHHHFFDFEEDDEEEDDDDCBBDDED
@5U8
GGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGAGCAGGCAT
+
@@@DFFFFHHHHGJGIIEBGHGHGIIJAEHHHDFHIDEEGHIIIJIJJGIJIIIIIJEEDFF@CDDDCDDCDDDDDADECDDDDB?ABDDDD@BBACDDDC
@5U9
CAGCAACACGTTTGAAATGAATGGCAAAGCTCTCCTGCTGCTGACCAAAGAGGACTTTCGCTATCGATCTCCTCATTCAGGTGATGTGCTCTATGAACTCC
+
?=@DDDBD?C<CDEHGGGGHABEGBGHGC@1CGC?DBGEHIEDGCGCFHI@HI(=;=CF;F@@5A;A=BDD7?A:C>;;@:>@3>>;5>CCC>@C@@C@C@
@5UA
CCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTT
+
CCCFFFFAFHHHHJJJJJHHIJJJJIHIJJJJJJJJJJJJIJJIIGGGIJJJJJJJJIJJJJJHHHHHFFFFFEEEEEEEDDDDDEDBDDDDDDDDDDDDD
@5UB
GTTTTGGTGAAGAATCAAAAATAATGGTGGAAGATAAAGTTTCTTTTGAAAATATGACTGTTGGAGAAGAAAGTAAGCAAGAACAGTTGATTTTGGATCAC
+
@@BFFDFDHFHHFIIJJJIGIJHIIJJCEGGJJGIIJJJGHGIGIJJIEIIJIIJGIIIJGGHJIIIGIIJJJHEEFHHFDFFFEEEED>CCDCCDCDADD
@5UC
TTCCAACCCCGACGAGATTGAAATCGACTTTGAGACCCTGAAGCCGTCCACACTGCGTGAGCTGGAGCGCTATGTCACCTCCTGTTTGCGGAAGAAAAGG
+
+:;D1B=AFFF?FEBF:GFEAC>9*B:?1DBCCAFFEFFCEFFEAAAAEEDDDDBCB'9=??>>?9<??B?9;AAB>AB:?@(>4:@A@9<5>><A?3>?
@5UD
CCAGGCTCTCCGAGGACGGGCTGCATAGGGAAGGGAAGCCCATCAACCTCTCTCATCGGGAAGACCTGGCTTACATGAACCACATCATGGTCTCTGTCTCC
+
CCCFFFFFHHHHGJJGJJJJJJJJJJJJJJJJJJJIJJJJJJJJJHHHHHFFFFFFEEDDDDDDDDDDDDDDDDDEDDDDDDDDDDDDDDDDDDDDDDDDD
@5UE
AGGACACCTGCCCACTGAATGTTCATTCTTATGACCCCCAAGGAGAAGGCAGGGTGGATCCTGATCTGTCCAAGCCTAAAAACCTTGCTCCTTTACAAG
+
CCCFFFFFHGHHHJJIJJJJJHIJJJJJJJJJJJIIJJJJJJIIJJJJJJIJJJDHIJHHHGHFFFFFFFEEEEDDDDDDDDDDDDDDDDDDDDDDDDD
@5UF
CGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCG
+
?@;DDDDDFDHHHFHIID@F@FIF>DDDFGGGHGH@F9=@@FEEAHFHEEEECADDCCCCCCACCCCBBCAACCC<@BBBBBBBBBBCCC:@AAAC@CCCB
@5UG
GTTACGCTTCCTCGACGCCACTTCATGTTCCAGTGCCTCGAGCGCTCAGGATGGAGGAAGACTCGATCCGCCTGCCTGCGCACCTGCGCTTGCAGCCAATT
+
@@@DFFFAHDHGHGIIJJEHHHJJIJJGGIIJIGHGIIJGIIIIIIJIHGGFFFBEFBEECDDDDDDDDDBDDDDDCCBDDDDDDDB<B@@BDCDDDBDCD
@5UH
TGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTT
+
CC@FDDFBBDFH?DHIBHHFHFHH@HIIIIIIIGIEEIIIGHEGGGGGCAHCHHF;EIII@EHEHEEA;>BEFCABCCCCC@9?BCCCBCBBB>BBB9?:>
@5UI
TGTCGGTCCGCTGAATGAAGTGCCCGCCCCTCTAAGCCCGGAGCCCGGCGCTTTCCCCGCAAGATGGACGGTTTCGCCGGCAGTCTCGATGATAGTATTTC
+
@@@FDADDHFH>DGEHIIGC?FFHIEEHIIIGIIIICHHIIIID==BCCBBCCCCCCCBBBBCC@CCCABB9@@ABB>BB9@@CCC@C>?DCBDCACDEAD
@5UJ
TGTTACCCAGTGGTGTGAGGGCTCCAGCTTGTATCACCATCTCCATATCATTGAGACCAAATTTGAGATGATCAAACTTATAGATATTGCACGACAGACTG
+
@@@FFFDDFHHHGAEGIHJIIJIIGGHJIJIFHIGCHIGGJ@FGIIHHIJIHGJJGCFCCHFFEHC@=DGGHGCHEACEFFEF@@CEEEACDDDD@DDBCC
@5UK
CACTTCTAAAACAGACACATGGTCCTTTGGAGTGCTGCTATGGGAAATCTTTTCTCTTGGATATATGCCATACCCCAGCAAAAGCAACCAGGAAGTTCTGG
+
??<BDDDDDDBDDEE@EE>EFD:3CEFEEE9EE@ED>@D@DCDICEIDEEIDD<BDDDBBCEEIIC78@CACCDCC?5?C>AD@2@A@A??>??=AA;>5:
@5UL
GATTATGTTGGGGAGAGAGTTGGGTATGGTAGCTGTGTGGGTTGGGGAGGGGGGTGAGAGTTGGGGGGGGGGCCGTGTGTGTTGGTTGAGGGTTTGAATGG
+
+++2+,22,<3?=+2)+++++2::?***)*0**0:**0))(0('-''(-'','&&&(((+((+(&)&&)00&&&&&&+((((((+((((+(((+(++((+(
@5UM
CTTCAAAATCCATTCCAATTCCACAGCCCTTCCGACCAGCAGATGAAGATCATCGAAATCAATTTGGGCAACGAGACCGATCCTCATCAGCTCCCAATGTG
+
@@@FFFFFHFHFHIIIEIIIGIIJJGIGHEGCHGHIJGGIIIJEGHDHHHFGGIGIC;FDCHIGHGGHHGFFFDDDDDD=;@BCCCCDD>CCDCDDCDD>C
@5UN
GTCTTTGATGAAGACAAAACTTTTGTAGCAGAAACATTGGAAATGGGTGAGGTTGTTGAAAAGGATACAACAGAACTCATGGAAAAACTTGAGGTAACCA
+
@@@DFFFFGFHGDFHIJJIJIHIJJIJJIJJGGIIGIIGEIJJIJGIDFHHHHIGIIJEHIIJIJDGGIJJHHCHECEEFDEEEDEBBCDCDDD:ACCCD
@5UO
CCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTC
+
@@<BDDDDFFHFDI>A1<CG;;3A9??*?EBG@?D?B9FDF@BF;?*8/BBFG=BFHIGGGECHH=.-;?3??;@CCCD;;;@C;5>CAC:@5@5>?:A99
@5UP
GAAAGTGCCTGTGAGGCCCAAGGACCCTGAGGGGGTTCCTCCTCTCCTGGTCTCTCAACAGGCAAAACGGGAGGAGGAGCGCAGCCCAGCTGCCCCACCAC
+
?<;D;BDDF8:DDA++::;3<<:8AGAG>CB?DF6'7=C9FF3=@D77CE)77?C;7?>7@9===@;?;88'382<50((&05)9881(24:988?<@58<
@5UQ
CTGACATCTCCTACATGCCTTCCTACCATGCCCACCAGCAGAAGGTGAACTTTGTCCCTCCCCATCCATCCTCCATGCCTGTCACTTCCTCCAGCTTCTTT
+
????B;?;?CDD+CE>ECBFE:CFCFE@DEIDDEEEDB=D>?DA>*?BDE9<DD9BCC=CDIID;@=ACCDC?.7))7@;.;6;;;A>>>>;=A<>AAA3:
@5UR
ATCAATTTGGGCAACGAGACCGATCCTCATCAGCTCCCAATGTGCATATAAACACAATAGAACCTGTCAATATTGATGACTTGATTAGAGACCAAGGATTT
+
?;@=DDDDFFFFD;EEGEEGFEG:?B>FEFCGFIIA@DF@FFFAECFFEE@DECEFFFF3;@B;;@(;@A@@B;>ADBDBBBBBBAAABA:???@8?84@A
@5US
ATTCAGGCAGTACTCAGCAAGGTACAACTATTCTTCAGTATGCACAGACCTCTGATGGACAGCAGATACTTGTGCCCAGCAATCAGGTGGTCGTACAAACT
+
CCCFFFFFHHHHHJIIJJJJJJCHHJJJJJJJIJJGIIIJIJIJJJJIJJJJJJJJJIIJIJJJJIJJJJJJJJJIHHHHFFFFFEE;@C>CDDDDDDDDD
@5UT
CTGGACAGATAGCTGGCGTGGATAAAGATGGAAGGCCTCTACAACCCCACGTCAGAGTGTGGGATTCTGTTACTCTATCCACACTGCAGATTATTGGACTT
+
CCCFFFFDFGHHAEGIIJCFGHIJJJIGGIJJJIBGHJJJJJJJJJJJJJJIIJJIF=>?CEFDFCEEEEEEDCDDDDDCDDCDDDDDCDDDDDEDDDCCD
@5UU
ACGAGGAGTGACTAAGAGAAACATTCTCTATGGTAGCACCTAGGAATATACATATCGGGCAGTGTTTCACAGGGGAGAGGGCCATTAAGGGCCACTTATCT
+
(((<23(()2=.2)2):@.;)))).))))))))))).2.(79)))..))90))03)0''''5)).))8)..:7,/','((,',(,(,7((((((+(+(+((
@5UV
CACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTCATCCAGCCTATGGGCAGCAGCCAGCAGCCACTG
+
CCCFFFFFHHHHHJJJJJJJIJJJJIJJJJJJJJJJJJJIJJJIJJJIJJJJJJJJJJJJJJJIIJI7AHHHHHFFFFFEDEDEBDDDDDDDDDDDDDDDC
@5UW
CCTCTTCACAACCTCTCCAAATACACAGACAAACTCCAGAAAGCAAGAATGCTACTCCCACCAAAAGCATAAAACGACCATCACCAGCTGAAAAGTCACAT
+
CCCFFFFFHHHHHJJJJJJJGJJJIIJIJIJGIIJJIJJJJJIIIJIJIJIJIJJJJJJGIIJJJJIFHHHHHFFFDDDDDDDDDDDDDDDDDDDDDEDDD
@5UX
CTTTTCTCCATGGCCTTTCCAGATAATCAGCGTCCACTGCTGAAGACAGACATGGAACGTCACATCAACGAGGAGGACACAGTGCCTCTTTCTCACTTTG
+
CCCFFFFFHHHGHJJJJJJJJJJJJJJJJIJJHJJJJJJIJJJIIJJJJJJIJJJJJJJJJJJJJIJJHHHFFDDDDDDDDDDDDDDDDDDDDDEDDDDD
@5UY
CAGGCTCTGCAGCCACATCCGACCGAGTCGTCCATGTACAAGTACCCTTCTGACATCTCCTACATGCCTTCCTACCATGCCCACCAGCAGAAGGTGAACTT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJIJJIIJJIJJJJJJJHHIJJJJJJJJJHHHHHHFFFFFFEEEEEEDDDDDDDDDDDDDDDDDDDDDD>CDDDDD
@5UZ
AGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGC
+
@@CFFFFFGHHHGJJJJJJJJJIIJJ?FHIHIJIGIJBFIIIIJJIIIJJJJJGGGGIIIGHJJJIJHHGFFFFDDDDDDDDDDDDDDDDDDDDDCCDDC
@5V0
GGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTT
+
CCCFFFFFHHHHHJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHHHFFFFFFEEDDDDDDDDDDDDEDDDDDDD
@5V1
TGGCAAAGCTCTCCTGCTGCTGACCAAAGAGGACTTTCGCTATCGATCTCCTCATTCAGGTGATGTGCTCTATGAACTCCTTCAGCATATTCTGAAGC
+
<@<?DEFFGDHHHII>FAHEGEGIJEGIEGIJIGIJJJJJJJJGEII@HHHGGGGIIIGG8@G@@7=AEHHHFHFDEFFFCECEC<CDAACCDACA>C
@5V2
GGAAAAGAAAAAAAGAAAAGCACAAAAGGAAAGAGGAAGTGGAAGAGAATAAAAAAAAGCAAAGCCAAGGAACCTCCTCCTAAAAAGACGAAGAAAAATA
+
CC@FFFFFHGHHHJJIHJJIJGGFHIIIJJIIJGHICFH=CGAFGEHGIIIIJIHFCDBBDCDDDDDCABBDBDDDDDDDDDDDDDDDCBDDBBDDDBAC
@5V3
GTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTAC
+
?+:BDDDDFBBFBG@GEGGIEFF?CHEF@BFG<GCGFEGFFIII<FFFIIIFDEFEIE<AEBFFIIACFFFDDDDA>ACABBA@AAAABBBBBBBABB@AB
@5V4
GTCACTTCCTCCAGCTTCTTTGGAGCCGCATCACAATACTGGACCTCCCCCACGGGGGGAATCTACCCCAACCCCAACGTCCCCCGCCATCCTAACACCC
+
CCCFFFFFGHHHHJJJJJJJJJJJJJIJJJJJJIJJJJJJJJJJJJJJJJJJJJIHHDDDDDDDDDDDDDDDDDDDBDDDDDDDDBDDDDDDDDDDDDDD
@5V5
CCAGTGCCGAGTTACGCTTCCTCGACGCCACTTCATGTTCCAGTGCCTCGAGCGCTCAGGATGGAGGAAGACTCGATCCGCCTGCCTGCGCACCTGCGCTT
+
BCCFDFFFHHHHHJJJJJJJJJJJJJIJJJJJJJJJJIJJJJJHIJJJJJJHHFFADDEDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDD
@5V6
CACCTGCCCACTGAATGTTCATTCTTATGACCCCCAAGGAGAAGGCAGGGTGGATCCTGATCTGTCCAAGCCTAAAAACCTTGCTCCTTTACAAGAGAGTC
+
1+1+?=+@;AA3<<A,,,<A<=AACB9+2@2<=))1;)?A5=)==A51(0.-'.7>ABBA37=7AA>?;7;;>>>>??6(-:((((595;?9>??71(2(+
@5V7
CCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIIIHHGHFFFFFDDEDDDDDDDDDDDDDDDDDDD
@5V8
CAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCAC
+
@C@DD>DFDHDHHIGHEEHIGIGBFGBFHCHII?FGIGEGC@CBFG=CFFFEG@GGIDEHBDBDE:A@AA?=AAB@CCCCAC>@@5<CAA:ACCA@ABBB@
@5V9
CACTGTGCTAAAGGCGGCTTTGGCTGATGTTTTGAGGCGTCTTGCAATCTCTGAAGATCATGTGGCCTCAGTGAAAAAATCAGTCTCAAGTAAAGGCCAAC
+
?@@?BD?DDDDDD<GGFGGGEEGG>FG<@B<<BB@AHHGFH<=;?EEH;@@D@DD;>;(>AC>;A?=;<>>:::>5>?5<@CC>@CCDA@44>::42818?
@5VA
CAAGTTTGTGTGTGATCCAGAAGCCCTTTTCTCCATGGCCTTTCCAGATAATCAGCGTCCACTGCTGAAGACAGACGGGGAACGTCACATCAACGTGGAGG
+
?8?B:=BB=ADFDG,A<2:B3:<3<8<+9+*1?49:*?D;3BB?0??09D**??*96(('-==)).=D;DEC;=76'',38?(,<<??ABB@A30++282?
@5VB
CTGTAGAGCCCACACCTGGGAAAGGACCTAAAGGTGTATATCAAATCAGCAAACAAATCAAAGCTCATGATGGCAGTGTGTTCACACTTTGTCAGATG
+
@@CDDFFFHHHHHJEHGJEGHGIJJIIGGHJJGI?GGIIIIIIJGIGEHGIJJEHIHHIJJJGIGGGIIAEFHHFF@D;@ACCEEDDDDDDACCDDCD
@5VC
CCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTAT
+
@<@D?DBDHAD;DFHG9:A:EABEFHCE=@>;DB??9FGH?F83;6/;B=;?EHDD@DE@ACC>A;>A@>?CBBCBB?B<@BAC@>:>A@<BBBBA?3:@:
@5VD
CCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCT
+
CCCFFFFFHHHHHJJIJJJJIGIIJJJJJFHIJJJJJIJJIIJJJIJJHIEGHIJJJJJJJJJJJHHHHHHFFFFDDDDDDDDDDDDDDDDEDDCDDDDDD
@5VE
CAAGAAAGAACCCCACAGTCCATGTTCAGAAATCAGCTCTGCCTGCAGTCAAGAACAGCCCTTTAAATTCAGCTATGGAGAAAAGTGCCTGTACAATGTC
+
CCCFFFFFGHHHHJJJJJHIJIIJIIJJJJJIJJIJJIIJGIJJJJIIHIJJIJJJJJJJJJJJJJJJJHHHHHHHFFFFFEEEECDDDDDCCDEDDCCE
@5VF
CCGAGACCTGGCCACCAGGAACTGCCTGGTTGGAGCGAATCTGCTAGTGAAGATTGGGGACTTCGGCATGTCCAGAGATGTCTACAGCACGGATTATTAC
+
CCCFFFFFHHHHHJJJJIJJIJIJIJJJJIIJJIIIJIJJJJJJJJJHIHIJIJJJJHHGFFFFDDDDDDDDEDDCDCDDCDEEDDDDDBBD@BDDDEED
@5VG
GAGGGATTGTAACTTATTTAAGGGTCCACTTAAGAGGAGATTAGAGGGGATCTTGTGGATTTGTGTCTCATTTGTGGCAGGTGTGGTGGGATGGAAAATC
+
++++2027+222,,22?,,3,<+3+3<+22721*:*11)114:0:*0)7(.-.).).())))))))...)=))...(((('(-5((,,(3(((+8(((+4
@5VH
CGCAGTCCATACCAGATAGCAGCTACCCCATGGACCACAGATTTCGCCGCCAGCTTTCTGAACCCTGTAACTCCTTTCCTCCTTTGCCGACGATGCCAAGG
+
CCCFFDFFHHHHHJJJJJJJJJJJJIJJJJJJJJJJJJJJIJJJJJJJJJJJJJJHHHHHHHFFFEEEEEEEDDDDDDDDDDDDDDDDDDDDDDDDDDDDD
@5VI
CTCCAACTGCCCCCCAGGCATACAGCCAGCCGGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTAT
+
@@@DDDD;A>FDFEEIFIII<1?C:CFCBGE)7?A6BBFFF5;;AEE7A@?D?@ACCBC>3;ABB;;8<@5:@BB:AA>>(4>>BB@??BBBB<@@BBBBB
@5VJ
GAGCAACGGCCCCAGCCAGATCCGTATCAGATCCTGGGCCCGACCAGCAGTCGCCTAGCCAACCCTGGAAGCGGGCAGATCCAGCTGTGGCAATTCCTCCT
+
<?BDFFFFGFHHHIBHHGHJIJJJHIIJIGHHGHIIJIJIJJJJIGHHFFFFDDD@DCCDDDDDDBC@DDDDDDDDDDDDDCCCDDDACCBCDDDCDACDD
@5VK
CATAATTACATGCGGTAAATCTCATATTTTCTTCTGGACCTGGAGCGGCAATTCACTAACAAGAAAACAGGGAATTTTTGGGAAATATGAAAAGCCAAAAT
+
@@@DDADDBDFBFEH@@CC?C?DHAHEHGEHGHEGCHGCEHEB@;BFHIGIIIEG@EEGHC@EEDDEBE@CCBBBCCCCBB:???ACCADDCCCBBCCC?C
@5VL
CAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCC
+
CCCFFFFFFHFHGIIIIGGIJFIHIJJJJJHIJJJJJFHJGIIFHIJGGIEGEEFHHFFFFFDCEEEDEEDDDDDD@CA@@CDDBDDDDDDDDDDCCDDDB
@5VM
CAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATG
+
CCCFFFFFHFHHHIHGGIIIIIJIIIIGHGHIGIIIJIJIJIJGGIJJJJIIIGEGHIJJJFJIGEEEHHHFFDDDDDBCCDDDDDCDDDD<B>AACCDDD
@5VN
CTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGC
+
@@<DFFADHHHHFHGIHEGFGGGIIIGDHIGHIEFHGGICHGGHGIJIGJIIAGIGGGIIEHCEGGFCEHEFFFFFEEEACC?CDBDDDDDDDDDBB><<9
@5VO
AACGGAACTGCCTCCTGAGAAGCTCAAACTGGAGTGGGCATATGGTTATCGAGGAAAGGACTGTAGAGCTAATGTTTACCTTCTTCCGACCGGGGAAAT
+
@CCDDFFDDHHHHJJJJJGIJIIIIJJJJIJIEIIGIJIIIGGHIFHHIJJHIJJJJJGHJJICEHFHHFFFDFCDEEEEEECDDDDDDDDDDDD<@BD
@5VP
GTCTTTGTCTCCAAGGTGGAGGCTGTCATTCACCCTCAATTTCTGGCAGATCTGCTGTCCCCAGAAAAACAGAGAGATCCCTTGGCCTTAATTGAGGAGCT
+
1=+<7A>2?AB72ACA?AC+?1A3<222?<AA7??A)1:7A=0=A<>>A<A>A4==A7=>ABBA2=>B>/6=7.);;.6;>;>;??;5;35=9=?==35;;
@5VQ
AAAATGTTTATGCGCGGTCGGCCAATTACCATGTTCATTCCTTCCGATGTTGACAACTATGATGACATCAGAACGGAACTGCCTCCTGAGAAGCTCAAACT
+
?;;DDD2B?FDFFE6F<@@E0)06BBBD9?FC>*99B<BBAFEB@FF<4(7)77ACABD))?;76;@63>;@BB3'5<85>@>>:?<>:?@B3+(::@>A:
@5VR
GCCAACAGAGCAGCAGCTACGGGCAGCAGACTGCATCAGGAGATATGCAAACATATCAGATCCGAACTACACCTTCAGCTACTTCTCTGCCACAAACTGTG
+
;;+AB::?DDDD;E+2C:<?:6C11??DCD)0:B*?D9**/7??B=B<<BC@CDDC@ACC>@)=?;?(.;>3.-5>A>:>-5>A3>A:>A>:(+2<24:4>
@5VS
GGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTT
+
CCCFFFFFHHHHHJJIJJJJJJJIJJJJJJJJIJJJJJJIJIJJJJJJJJJJJJIJJJJJFHHGHHHFFFFFDDDDDDDDDDDDDDDDDDDEDDD9<<@C
@5VT
ATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCC
+
@B@FFFFFHHHHHJJJJJJJJJJJJIJJJJJJJIJJIJIIJJJJJJJJIIIIJJJJIJIJJJIIJJJJHHHFHHFFFFFFEEEEDDDDDDDDDDDDDDDDD
@5VU
GAATTTTTTAGAGTTGACAGAACAGAGTCAAAAATTACAGATTCAATTTCAGCAATTACAGGCTAGTGAAACTCTGAGAAACAGCACTCATAGTAGCAC
+
B@BDFFFFHHGHHIJJJJJJJJJJIJIJJJJJJJJJIJIJIJJJJIJJJIJJJJJJJJJJJJJIIIIJJJJIHHHHGHFFFDFEDEEDDDDDDEEEDDD
@5VV
CTGGTTTCCAAACAGAGGATTTTAGTCTATATGCTTGTGCTTCTCCAAAAACACCCATCCAGGCAGGGGGATATGGTGCGTTTCCTGTCCACTGAAACAA
+
CCCFFFFFHHHHHJJIIJIJJJJJJIJIJJIJJJJJJEHIJJJJJJJJJJJJIJIIJJJIIJIIJJJHHFDDDDDDCCDDBDDDDDDDDDDDDDDDDDDD
@5VW
CACAAAGCCACAACTGGCTATTGTTACCCAGTGGTGTGAGGGCTCCAGCTTGTATCACCATCTCCATATCATTGAGACCAAATTTGAGATGATCAAACTT
+
CCCFFFFFHHHHHJJJJJIJJJJJJJIJJJIHIJGHHIJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJHHHHHHHFFFFEDDEEEDEDDDDDEDEDDDDD
@5VX
GGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACAC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJGIIJJJJJJJJJJJJJJJJJJJJJIJJHIJJJJJIJJJJJHHHHHFFFFFDDEEDDDDDDDDDEEDDDDDDD
@5VY
GCTTCCCAAGCCTCCCAAGCCTGTGAGCAAGATGCGCATGGCCACCCCGCTGCTGATGCAGGCGCTGCCCATGGGAGCCCTGCCCCAGGGGCCCATGC
+
?@@;:DDDHHFFHGGIIHIIIGGIGIIEEIEGIICGGIIIIIIIIEHG<GGFEEEEEEEEEB>BBBBBBBCCCA<CBBBB?BBBBBBBBB<BBB<AC?
@5VZ
TACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTT
+
@CCFFEFFHFHHHJIJAFHIJIIIGGIIJJIIIJJJJJJJIJJGHGIIJJJJIJJIHIIIJDEGIIHHHHGFFFFEEEEDECDDDCCDDDDDD@DDDDCD
@5W0
CTTCACAATGCAAATTAGTTTCTTGCAAGAGAAAATTAAAGTATATGAAATGGAACAAGATAAAAAAGTAGAAAACTCAAATAAAGAAGAAATACAGGAA
+
@@@DBDFDDFHFDGEHGG<EIHGAHBFHDGHJJGIIIJGFGIGIGIDABCHIIDDHIEGGIJHGIEEH@EHIIIHHF>EEFFFFFDDCCEDDCDDCCCDD
@5W1
CATGAACCACATCATGGTCTCTGTCTCCCCGCCTGAAGAGCACGCCATGCCCATTGGGAGAATAGCAGACTGTAGACTGCTTTGGGATTACGTCTATCAGT
+
CCCFFFFFHHHHHJJJJHIJJJJJJIJJJJJJJJJJJJJJIJJJJJJJJJJJJIJJJJHHHHHFFFFFEEDEEEDEDDDDDDDDDDDDDDDDDDDDEDDED
@5W2
CAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAAC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIHHHHHFFFFFFEEEEEEEDDDDDDDDDDDDDDDDDDD
@5W3
CGCTGCCTGAAGTGTGCTCTGAACAGGACGAACTGGATTTCCTCATGGAAGCCCTGATCATCAGCAAATTCGACCACCAGAACATTGTTCGCTGCATTGGG
+
CCCFFFFFHHHHFHHJJJJJJJJJJJJIJJJGGGIJJJJJJJJJJJJIJJGJJJJJJJJJJJJJJHHHHHHFFFDDDDDDDDDDDDDEDDDDDDDDDEDDD
@5W4
CCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTAT
+
@@CFFFDDHHHHHJBHIEIGEGGHGGDGGGGGHIFBFIGGHHGIIGGIIFGHHGDBCFFCEEEEDDCCCDCDDB?BDB?B?BBDDCDDDBCDBDDDDCAC@
@5W5
CTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTC
+
BC@FDFFFGHHHHJJGIJJJJGIJGGIGIJIIJIIJGG>?FGHGGGGJJIJEGGGGGIJJHHBGGJHHFFEDDCCDDDDDCDDDDDDDDB@CCCDEDDDAC
@5W6
TATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGG
+
?@@FDDDDHHDHHEHIEIGGIIIIDDHGGGHG?FGIICGHCHIIJIIGHHHF=>DDDFEAEACEDECCCCBDDDDDD?B?B>>:ACDDDDBBDACCCDDDD
@5W7
TGGCAAAGCTCTCCTGCTGCTGACCAAAGAGGACTTTCGCTATCGATCTCCTCATTCAGGTGATGTGCTCTATGAACTCCTTCAGCATATTCTGAAGC
+
@?;DDDDDFFA>DEEHB9E>EFHHGHII;EFGDHHGDCFGBAG9)??BBCGCCEGIGICDC;;;4.7=AAEH@HEB@3?BCA:@ACCCACACB@ACCC
@5W8
CTTCAAGAAAAATTTGCACAACTTGAAGCAGAGAATAGCATTCTTAAAGATGAAAAGAAAACCCTTGAAGACATGTTGAAAATACATACTCCTGTTAGCC
+
CCCFFFFFHHHHHJJJJJJJJIJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHHHHFFFFFFEEEFEEEDDDDDDDDD
@5W9
CAGGAGCCGGACAAACGGCCGGTGTTTGCGGACATTAACAAAGTCCTGGAGAAAATTCTGATTAGGCGGAGAGAAATAGGCACAAGGCAATGCCGGAAA
+
9(-(8(2<(--33()((((:(-00-7>))'5===?)8);=).).(.:((((70-(((,,(((,(((())5:9(6((43(+(((+((++((+((()&)59
@5WA
GGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGA
+
?1+=ABD;CDD><E>E@E+<CFE@C+ACF>EEE@EEIDDDDDECEEIIDEEABBDDD@CB6;A=CDI@DDCDD@DDDD>AA@@A>>;??58'3;??>>>>
@5WB
GTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACT
+
CCCFFFFFHHHHHJJJJJJJJCHHJJJJJHJJJJJJJJJJJIJJIJJJHIIJJJJJJJJJJJIJIIJJHHHHFFFFEEEDEEDDEEDDDDDDDDDDDDCDD
@5WC
GGCAAGTCCAGGCACAGATGGAGTACAGGGACTTCAGACATTAACCATGACAAATTCAGGCAGTACTCAGCAAGGTACAACTATTCTTCAGTATGCAC
+
@<?D?DDDAF>8;<CFBF<CB;A3A?B@9C8CF><DDGIIEDGDDFBGEHGI@DHGE=C>FHDFEGGG;;C@A?E?C;BDCBACDDD6>AC>A;@;@A
@5WD
CCTGATCTGTCCAAGCCTAAAAACCTTGCTCCTTTACAAGAGAGTCAGGAGTCTTACACAACTGGGACTCCCAAAGCAACATCTTCTCACCAGGGCCTTGG
+
@@@B?DEFHFFHHIIIJJJJIIJIIIJJJJIJIEHGGID@FGCGHGIIJJIDGHHHIIGHIJHGIIJJJGHHHHDCDFFECCCCCDDDEDDDDDDBBBDCD
@5WE
GGGGGGTCAGGGTCCCAGATGCACAGGAGGAGAAGCAGGAGCTGTCGGGAAGATCAGAAGCCAGTCATGGATGACCAGCGCGACCTTATCTCCAACAATG
+
@@@FF??BDDDB?CBDDDDDDDDDDDDBDDDBDBACCD@BBBDDCCDDDDDD?@CCCCDCDDDDDDDDDDBACDDCCBDDBD@BDDDDDCCDDCDCBDDC
@5WF
TAAACACAAAAATAATAGAAGAAGAAAAGAAAACTCTTGAGCTAAAGGATAAATTAACAACTGCTGATAAATTACTAGGAGAATTACAAGAACAGATTGTG
+
@CCFFF?DHHHHHJJJJJJJJCGIIJJJJIJIIJJJJJJIIJJJJJJJJJJJJJJJJIJJIIJJJJJJIJJJIHHHGHHFFFFFEEDEEEDDCCD3;ACCC
@5WG
CCGAAACCTGACCGGGCCTTCCCAGCTCACCTCCCTCCATCGCAGTCCATACCAGATAGCAGCTACCCCATGGACCACAGATTTCGCCGCCAGCTTTCTG
+
CCCFFFFFHHHGHJJIJJJJJIJIJJIIJJJJJJJIIJJIJIIJIEHIJJHHHHHFEFEFFEEEEEDDDDCDDDDDDDBDDDCDDCDDDDDDDDDDDDDD
@5WH
ATGGCCCTGAATGTCAAGGCTTGTCCTCCTAGGAGGGCTAGGGGTGCCCATAGGGAGGGCTCTGCCGGCCTTTTGTGGCTAGAGGAGTCTGCGGTGCTGTG
+
CCCFFFFFHHHHHJJJJJJJJJJIJJJJJJJJJIIJJIIIJJJJDFEIJJJIJJJGHHFFFDCCEEDDDDDDDDC?CDBBCB:@B2<+3:A>9@&55>A4?
@5WI
AGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJIJJIJJJJJJJJIJJGHJJHHHHHHFFFFFFECEDDDDDDDDDDDDDDDDDDDDDDDD
@5WJ
CGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCG
+
?<;D?<DDH?FH?<FH@HA:1?::?DGB0086B;)*/..6'5@;EA<8?DEB;@>;;;;C(5(-5;?BB::>:,5<@-0588(0<B?344>:3:@444:3&
@5WK
ATCAAATCAGCAAACAAATCAAAGCTCATGATGGCAGTGTGTTCACACTTTGTCAGATGAGAAATGGGATGTTATTAACTGGAGGAGGGAAAGACAGAAA
+
CCCFFFFFHHHHHJJJJIJJJIIJJJJJJJIJJJJIJFHHGGIJJJJJJJJJGIJJJJJJJJJJJJJJIJJIIIJHHHHHHF>BF?BDDDDDDDDDDCDD
@5WL
CGACTTTGAGACCCTGAAGCCGTCCACACTGCGTGAGCTGGAGCGCTATGTCACCTCCTGTTTGCGGAAGAAAAGGAAACCTCAAGCTGAGAAAGTTGATG
+
:???DD8:2:CB?GG;FA??A82<EGEFDFDGE?F?6???BF@FFA;@AD@DEEEEAE)7).;;69>'8;,599:89>>>89?ABA:A:@2>>9@BAB>AB
@5WM
CTCCGTCCAAATCGACCTTTCCTTTCTATCCCCAACCACCCCTCAACCCCTGTTTTCCCCTGCCTTCCTTGCAGAGGCCATGGAGGACGAGGAGAGAC
+
@@@FFFFFHHHHGIJGJIGHJIGHJIJJJJIJFIIJIIAEGHHEHHGIJJIJGHIJEHHGHDFFFFDDEEDEDDCAB@BDDCDDBDBB>BBD<??@BC
@5WN
AGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAA
+
BC@DFFFFHHGHHJJIJJIJJIIHIJJJJJJJJJJJJJIJJJJJIJJJJJJJHHHHFFFFEEEEDDDDDDDEDDDDDDDDDDDDDDDDDDDDDDDDDDD
@5WO
GCCAAACATCCCCTTCCCACCTCAAGGCTTTAAGCAGGAGTGCCACGACCCAGTGTATGAACACAACACCATGGTTGGCAGGGCGGCCAGCCAAAGCTTTC
+
?1:DD;8DBA;3::?CEEA@?+2CF93::?;9<DE?3:0?09*0*0(?'746(=37@C7?;CD>;=;?@>2;>AAA;?:>8'3<&5;??<0<>><<<((::
@5WP
TATTAAAATGTTTATGCGCGGTCGGCCAATTACCATGTTCATTCCTTCCGATGTTGACAACTATGATGACATCAGAACGGAACTGCCTCCTGAGAAGCTC
+
@@??DDDDCFHDAHG<CG<FE?FDGAHBGGII@FGGEGIDEACGGIDAHHECB=?ACHHEEEB@CA:;A:@>CC@CCCBBBBBCCCCCCB<AACCCCCC>
@5WQ
GCCAGCTATGAACTATGATAAACTTAGCCGTTCACTCCGCTATTACTATGAGAAAGGAATTATGCAAAAGGTGGCTGGAGAGAGATATGTCTACAAGTTTG
+
CCCFFFFFHHHHGJJJJJGIJJJJJJJIGIIJHIJIIJIIIJJIIIIIJIGIIGGIGIIEGGGIJIIGIIGEEHFBDFBECD@??CCD@DDEFCCCDCCDD
@5WR
CCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGG
+
@@?DDAADHHHHHIIIIIIIIIFGGIDGIIII>FHGGIGHIIGIIGIFGGIAHCGHEHCHHHCEFFDEEECEACDCBBD@9@@DDDDDD<A@B?<BD?C9C
@5WS
CCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCC
+
@@@DDF>D>;FFFHE@F6E;?CEGH9FDFECF;D?BD9?DDGD9BDGGG=;F>FH6@DCGHHH>8=;;;BCCBCC?=;>>CC:AC:?@?9?<<ACAC>:43
@5WT
CTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTAC
+
@@CFFDFFHGFHHHEHFHIGGIGIGIGIEGIIIJDHIDHIJJJJIJJJICHIGEEEEHDFFFFFDEE@CACCCDDDCDCDDDDDDDD>CCDDDDDDDDDDD
@5WU
CGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGG
+
CC@FFFFBFBHHHIIIECHHIGGIGIIGIIGIIIIIIIIIIIIIIGIGIIIIIGGGHIIIIIIHHHHGFFFCDCEDEEDDDD@CCDDDDB?CDCBDCDDDD
@5WV
GTTTGCTGGATGGAATCTTCACTACTCAATCTGATGTATGGTCTTTTGGAATTCTGATTTGGGAGATTTTAACTCTTGGTCATCAGCCTTATCCAGCTCAT
+
7----)<;1(=)(:.2.8).2@)96<?1.)@);)))..2)==)=:>1)-.<.;3)).=<3795(('./.>;>1)8.)..)...;)..;==8=;.9((:;5(
@5WW
GGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATAC
+
CCCFFFFFHHHHHJJJHIJJJJJJJJJJJJJJIIJJJJJJJJJIJJJJIJIJJIJJJIJJJHHFFFFEEEEEEEDDDDDCDDCBDDDDDDDDDDDACDDED
@5WX
CTTTGTTATCGGTAAGGGTGGGTGGTTTTGTGGTGTGGTTTTAGATTTTAAAGTGAAGGAGGTGTTTTTTATTTTTTAAGTAAAAATAAAATAGGAAGGGG
+
111+22+,2,+)22+2+2+<):4):):=?)00)077(<)-.-)).)7=>.))).7)).7(.4(.(,(((,((,,,,&(((+((+(((((+((((((((+)&
@5WY
GAACACAACACCATGGTTGGCAGTGCGGCCAGCCAAAGCTTTCCCCCTCCTCTGATGATTAAACAGGAACCCAGAGATTTTGCATATGACTCAGAAGTGCC
+
=1?:=AA?DD?DAEIE:EDEE@?EDEAADDDCC;BD8B3BCC<@>CDDAD==AC:=?@D>;@A36;;;?;>???9?(,:3>A:4::+4>44(+4>>AAA>>
@5WZ
CTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCAC
+
CCCFFFFFHHHGHJJJJJJJJJIJJJJJHJIGIJJJJJIGHIJJIJGIIJJIIJJJJDHIHJGHHGFFFFFEEDEEEDDDDDDDDDDDDDDDDCDEDDCDD
@5X0
GGCAGTTTTATGATGACACCTGTGTTGTCCCAGAAAAATTCGATGGAGACATCAAACAAGAGCCAGGAATGTATCGGGAAGGACCCACATACCAACGGCG
+
CCCFDDFEHHHHDIIIIIJJJJHHJJIJIJJJJIJJGHJJJIGEIIGHHIIJJIGHJJIIGGIGHIIIJHHEHHHFEDCD?BDDDDDCDDDDDDDBBBBD
@5X1
ATCTACCCCAACCCCAACGTCCCCCGCCATCCTAACACCCACGTGCCTTCACACTTAGGCAGCTACTACTAGAAGCTTACTCATCAGTGGCCTTCTAGCTG
+
@@@BDFADFHFHDIIEEDEHIH>H:FEDDGAHD?=;FHHE@EH6AAECF;?D@DECCECC;??C>>CA@C5@:::?CACC@CCCCCA:>C?BCCCCCC>:>
@5X2
GCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGC
+
CCCFFFFFHGHHHJJJJIJJIIHJJJJIJJJJJJJJJJJJJJJJJIJJJJJIHIJIJJHHHFFFFECEDDDDDDDDDDCCDDDDCDDDDDDDDCCDDDDD
@5X3
CCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGG
+
CCCFFFFFHHHHHIIJJJJJJJJJJJJJJJJJJJJJJJGIJJJJJJJJJJJIJHHHHFFFFFFEEEEEDDDDDDDEDDDDEDDEDDDDDDDCDDDDDDD
@5X4
CTTCTGATAAAGTATCTAAACTAGAAGGTCAAGTAGAATCTTATAAAAAGAAGCTAGAAGACCTTGGTGATTTAAGGCGGCAGGTTAAACTCTTAGAAG
+
CCCFFFFFHHHHHHJJJJJJJJJJJJJJHJJJJIHHIJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJCGHIIJJIJJIHFDDDDDDDDDDDDDDDDDDD
@5X5
CATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJHHHHFFFFFFFEEEEEEDDDDDDCDDDDDDDDDDDDD
@5X6
GATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCC
+
C@@DFFBD>FFDFHDBFFHIEEHIIICCHIIIECFGGHIIIAH<FEHIIIGGHIGIIIIE@?CEHHHCDDF;@CCEECEACACBCC@C@?BC@BBBBBCCB
@5X7
ACACAACACCATGGTTGGCAGTGCGGCCAGCCAAAGCTTTCCCCCTCCTCTGATGATTAAACAGGAACCCAGAGATTTTGCATATGACTCAGAAGTGCCT
+
CCCFFFFFHHFHHGHGJJJJJGIIIIIJJJIIJJIJIJJJJFIIJJJJJJHHHFHHHFFFFFFEDDEEDDDDADCDDDDDDEDDDCDDDDDDDDDDDCCD
@5X8
AGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAA
+
@@@DDDDDDHDFHIIIIEHGII@@1CCFDFHIDAH?FGG<FGIIGGIBGHGGB?EHEBEECCCCCBCCCCCDCCCCBBCBBBBBBBBCCCDAB?CBBBB
@5X9
CTCGATGGAGTGGGTCCCATCAGTTTGAACAGTTGTCTGGATCCATTTTGTGGATGGCACCAGAAGTCATCAGAATGCAAGATAAAAATCCATACAGCTTT
+
CCCFFFFFHHFHHJIIIJJJJJJJJJJJJIJJIIJJIJJJJJJJJJJJIJGIIJJJJJJIJJIIJICHIGHHHHHGFFFFFFDEEEEEBDDDDDDDDDDDD
@5XA
CCGAGTCCCACCCGAAGCCATCCAGCCCCCGGCAGGAGAGCACACGCGTGATCCAGCTGATGCCCAGCCCCATCATGCACCCTCTGATCCTGAACCCCCGG
+
@CCFFFFFHHGHHJJJJJJJJJEIIIGIJJIJIJJJJJIIHHHHHFFDBBDDDDDDDCDDCDCDDDBBDDDBDDDDDDDCCDBDDDDEDDDDDCADDDDBB
@5XB
ACCTCTCTCATCGGGAAGACCTGGCTTACATGAACCACATCATGGTCTCTGTCTCCCCGCCTGAAGAGCACGCCATGCCCATTGGGAGAATAGCAGACTGT
+
@<?DDDDBDDBFFGIEGHECC>FHG@AEFACGCGFEGEGECCAGG<DFHGHBFGGGGEG@=<CC?C@D>C@C>7;=A::<@A>CCB?@9<::A>:A<1:@4
@5XC
CAAAAATTCACCGCAGTGCATCAGAACCCTCCTTGAATCGGGCTGGTTTCCAAACAGAGGATTTTAGTCTATATGCTTGTGCTTCTCCAAAAACACCCATC
+
CCCFFFFFHHHHHJJJHIJJJJJJJJJJJJJJJJJJJJJJJJJJJJHIJJJJJJJJJHHHHFFFFFFEEEDEEEEDEEDBDDDDDDDDDDDDDDBDDDDDD
@5XD
GTTTATTTCATTGCATCAGTAGTAGTACTATTTAATTATGAGGAGAGAACTCAGCGACACTACCTGGGCCATACAGACTGTGTGAAATGCCTTGCTATAC
+
@@?DDEFDHGGDFDHHIIDFFEIEE3AEFHDGGGGGHGD@GHGBG?DGHGIEHACHBGEH>FGIIIIGIHHGGFDD@;?@AA6>ADCCC@CDCDDDDDDD
@5XE
GTACGGAGTAACTGTCCAAAAGCCATGAAGAGATTAATGGCAGAGTGCCTCAAAAAGAAAAGAGATGAGAGACCACTCTTTCCCCAAATTCTCGCCTCTAT
+
@=?DDDFF;CDFDGEHIIIIIIIIGIGHIIIIIIIHGIHIIIGFGFEGHGGGGGGGHHEEFGGGCGHFFEFDCB@C@ACEC@CCCCCBCCCCC?BBCBCCC
@5XF
GGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCAC
+
@@@ADDDD<FADFHHIHHGGGEHIGHEGIGB?F@DGHIIIFHIIFHGGIGDHGGIIIIIECECEHFB??@BBCCCCCCCBCCBCBCCCCCC@B09C@CBCC
@5XG
AAAAGTCCTCCCCTTGGAGGGGCACAAACGATCAGTAAGAATACAGAGCAACGGCCCCAGCCAGATCCGTATCAGATCCTGGGCCCGACCAGCAGTCGCCT
+
CCCFFBDDFHHHHJIIJHIIJIIIJIJJIGIGCHGFGIGIJIJJJIIJIJJJBHGDFCCACDBBBDDDD@BDDD>CDDDDCCDBDDDBDDDDDDBCCBDDD
@5XH
ATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCC
+
CCCFFFFFHHHHHJJJJJJJIJJJJJJJJJJJJJJJJIJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJHHHHHHFFFFFFEEEEEDDDDDDDDDDDDDDDD
@5XI
CACCACCCAGGCCTCCTATGCAGCCCAGCCTGCCTACGCCCCCCACCCCCCCTACCCCCCCCCCCCCCCCCCCCCCCCACCCCCCCCCCCCACCACCCCCC
+
C@@DFFFFHGGHGGGIJJJIJEHI2C)1):)1?)**)))8(<';-':B/'9''((5<()5<0))&&&0&)5&)5>0&5&&0>0<&&5)9@5&5&(((09)9
@5XJ
CCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGT
+
>==<AA+<+22AA73CAA08A)11?7A7==2A;==AABBABA>;7AAA=AA>>.=AAB@@>).7>;>@@@?;55;;>:?((;5'(58<;=7(8=?8(8;;3
@5XK
GGAAACCTCAAGCTGAGAAAGTTGATGTGATTGCCGGCTCCTCCAAGATGAAGGGCTTCTCGTCCTCAGAGTCGGAGAGCTCCAGTGAGTCCAGCTCCTCT
+
CCCFFFFFHGHHHJJHIIJJJHHJJJJIIJJJJJJJJJIJJJJIJJJJJJJJJJJJIJJJJJHHHFFFFEFCEDDDD@DDDDDDDDDDDDDDDDDDDDDDD
@5XL
CAGATACTTGTGCCCAGCAATCAGGTGGTCGTACAAACTGCATCAGGAGATATGCAAACATATCAGATCCGAACTACACCTTCAGCTACTTCTCTGCCAC
+
?8?;DB?DBFFHFGBGGHIGIBGHEC<@EFEHE?GGGE?FDB9?D9*?1D@F>@A@FH9F;F7CGIIIIFH<EDB;ACCCACC@>@CCCCA@@>CC:@AC
@5XM
GCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTGCAGTTATCCCCAGGTACCTGGG
+
CCCFFFFFHHHHHJIJJJJJJJJJJIJIJJJJJJJJJJJGHIJJJJJJJJJJJHHHHFFFFFEEEEEEEDDDCCDDECDDDDDDEDDDDDDD@CDDDDDD
@5XN
CCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAATGTGACTCTTTCCTCAGGTTCATTCC
+
CCCFFFFFHHHHHJJHGJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJIJJJJJHHHFFDDEDDDDDCEEDDDDDDDDDDDDDDDDDEEEE
@5XO
GAAAGATTGATTTTCTTAGACTCCATTAAGTCCAAATCCAAAGACTCTGTGTGGGAAAAAGAAATAGAAATACTTATAGAGGAAAATGAGGACCTCAAAC
+
@@@DDDDEHH<FHGIHGEHEBHBDHGGHBEBFHGHGHHGHIDGGIHEGB?B0?DGGEHICEAGF;@FC@@;D;@GHFHAECFEDEF>>@ACEA?=>ACA@
@5XP
CATCGCAGTCCATACCAGATAGCAGCTACCCCATGGACCACAGATTTCGCCGCCAGCTTTCTGAACCCTGTAACTCCTTTCCTCCTTTGCCGACGATGCC
+
CCCFFDDDAFHDFGBGIED@C@EADDEHGGIIBDCAFGGGEDFHCDFB9@AHBBGHHED@CBEE>ACCEA>ACCECCCCCCC@A?ACCCCC@<>@<B08A
@5XQ
CGGATAATGACTCAGTGCTGGCAACATCAGCCTGAAGACAGGCCCAACTTTGCCATCATTTTGGAGAGGATTGAATACTGCACCCAGGACCCGGATGTAAT
+
@@<DDDDDA:?DBCFIIE@FEGECFEFGC><GBFCEEGDH>?G?FHGIEEHH@HCHHCEFAC@B@77?AHHEEEEE@CC@C>@CB?BBBBA?=B>50>CCA
@5XR
GGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCT
+
@@@DFFFFHHHHHJJJIJJJJJJJJJIIJJJJIIIFHIGJJJJIJJIJJJJJJJIHJJJJJJIIJIEHHHFFFFFEEEEDDDDDDDCDDDCDDDDDDDDD
@5XS
AAATCTTTAAAGCAAGAGAAAGAACAAGTTTCATTGAGATGTAGAGAGCTAGAAATCATTATTAACCACAACAGGGCAGAAAATGTACAGTCATGTGATAC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJIJHHIJJJJJJJIJIIIGIIIJJJJJJJJIJJJJJJJIJJJJJJJGIIJHHHFFFFEEDDFEDEEDDEDEDEEED
@5XT
CTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTAC
+
CCCFFFFFFHHHHJJJJJIJJJIJGJJJJIJIIJGIIIJJJJJJJJJJJJJJHHHHHHFFFFFFDEE>CCDEDDDDEDDEDDDDDDB@CDDDDDBBDDDDD
@5XU
GGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCC
+
?1;BDDDFBHFHHGG>BB?G>AAFHEHGIIEIGI>@GGGIIAGCIIIEEHIICE?ACEDFDDFCC(;ACCBAC>@CC@C@A@C559?@>))2::4@????B
@5XV
CCTATAGGCAATCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAAACCACCCAGGCATATGGGCAACAAAGCTAT
+
59;8(@8)<68)).))22)@33?2;..--.(..0.0)>3>))<?'7-=9.<?;?636..).(66.(7(-:(9/5((,,,((2222(8/(826(((((562;
@5XW
CGAGCAGTTATTCCCATGTCCTGTATAACCAATGGAAGTGGTGCAAACAGAAAACCAAGTCATACCAGTGCTGTCTCAATTGCAGGAAAAGAAACTCTTTC
+
@@<DDFDEHADFFGGIJFIIGEHFGHGHIJIJIGIBCE??D?DFHDGIIGIJHGIIGHIHCGIIIHIICHGIIHHFC?EHFE>CDFDEEEEDDDDCCCCDC
@5XX
GGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTT
+
=??DB;AD>FFAH3?EGGGGIGIIGGICC?C:DGCEHGHIGGCHHGCHHIGGIIIIGIIFGEEGHIFAEECFDDD@BABBB>BC@C>CCCDCDC>CCCA>C
@5XY
CGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCG
+
@?@DDA<:A:CHA;C:C)2?:CDC@B@G;88?DF@G><FAFHI;@EAEEBCEC>6;AC>;@C;C>><55:@(>::00009@8<5<8??@A>ACD@:A>:>&
@5XZ
CCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATG
+
CCCFFFFFHHHHHJJJJJJJJHFIJIJJJIJHJJIIIJJJJJJJJJJJIJJJJJIGIIJJJJIGHHFFFFFEEDEFEEDDDDDDDDDDDDDDBDCCCDDDD
@5Y0
AAGAGGAGTATGCTTGCCTTCTCAAAGTAAAAGATGATTTAGAAGACAGTAAAAATAAACAGGAATTAGAGTATAAAAGTAAACTTAAAGCACTTAATGA
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJHIJJJJIJJJJJJJJJJJJIJJHIJJJJJJJJJJJJJJJJJJIJEHIIJJJHCHHHHFFFFFFEEEEEEDEDD
@5Y1
CCCGGATGAGCGGGCCCTCACCATGGGCGACCTCATCTCATTTGCCTGGCAGATCTCACAGGGGATGCAGTATCTGGCCGAGATGAAGCTCGTTCATCGGG
+
@@CDD88@B>FHA6DADGGDDDG>@@C@;AHHG@=DEA>CHC=BC3?C?@CA@C?DCCAC:5<;//28C>4@>A>CCC?&909?4>C<@4>55?AC:A305
@5Y2
ATGTTAGAAAAAGAAAAGAATGCTGTGTTAGACAGAATGGCTGAATCACAAGAAGCTGAATTAGAGAGGCTGAGAACACAGCTTCTATTTAGTCACGA
+
????BD>DD?+2<+2ACEC@EE:AB<CEDE@E*?9CDDDD8BDDIAD>DDED;BDCDDD@CCAAC7);(;C(62?A??);((6;A>>>AD;3>A>A=7
@5Y3
CAGTAAGGTACGGAGTAACTGTCCAAAAGCCATGAAGAGATTAATGGCAGAGTGCCTCAAAAAGAAAAGAGATGAGAGACCACTCTTTCCCCAAATTCTCG
+
@@@BDFFAACFFHIJCFHICHHHIHIJGGIJEGGGDHHIIEGHGIICGGGFF9=CFHIHIIJJJGGIGE?EEFEEFFCDCDDBCCCCDDDDDCDDCACDDD
@5Y4
GGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGC
+
@?<DD@DDBFCDDF>FFE@EHHEEA?GCBFBBHIGHIIIIIGDHHI@AEHEBFFFFFDCCC@EAACBBCC??AA==BB9ABBB?BBCCCDCCCCCCCCCB>
@5Y5
GAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGC
+
@<;=?DBDD7AACG93CD8?CF?BF@GFFDDFDEF@F>DB*?8B;==383=;C/55'=D2(,(5=@BABABAA@AA@B@>BB5<@??@8??A?A>8:@343
@5Y6
ACACAGCCGGAGGTCATACTGCATCAGAACCATGAAGAAGATAACTGTGTCCAGAGGACCCCCAGGCCATCCGTGGATAATGTGCACCATAACCCTCCCAC
+
CCCFFFFFHGHHHHGIJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJIJJJJJHHHFFFDDDEDDD?BDDDEDCD@DCDDDDDDDDDDDDDDCD
@5Y7
GCAGATCTCACAGGGGATGCAGTATCTGGCCGAGATGAAGCTCGTTCATCGGGACTTGGCAGCCAGAAACATCCTGGTAGCTGAGGGGCGGAAGATGA
+
@<@FDDDDFBHFHGEHIECEEBCFHFGIGIGGBFA;DFGEGGGGAFDBCGIIE<AHHGDFEFDCBEDDCCDACDCCDA>ACCCDDD@@<<B<9>1>@C
@5Y8
ATTCTTGGGAAAATTCAGATGATAGCCGTAATAAATTGTCGAAAATACCTTCAACACCCAAATTAATACCAAAAGTTACCAAAACTGCAGACAAGCATAA
+
=7=?1?4=ABCBC+++,<,?CA>,773?111:@AA?==*10?AAA9?=>A?AB9AB1(45((=;A=).)=3A@@@)6>(;>@=22(53=??==:=(55;:
@5Y9
GCCGTCCACACTGCGTGAGCTGGAGCGCTATGTCACCTCCTGTTTGCGGAAGAAAAGGAAACCTCAAGCTGAGAAAGTTGATGTGATTGCCGGCTCCTCC
+
CCCFFFFFHHHHHJJIJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJHHHHFFFFEEEEEDDDDDDDDDDDDDDDDDDDDCDEEEDDDDDDDDDDDD
@5YA
CAACAAATGAAGTTGTTTTGGCTGTGGAGTTTCACCCAACAGATGCAAATACCATAATTACATGCGGTAAATCTCATATTTTCTTCTGGACCTGGAACGGC
+
C@CFFFFFFDHHFIJJIIJIJJJJJIIIGGHJIGIGJIIIIJIJJJJJJJJJIJJIJJJJJGIIGHGEHHGFFFFFFFDEFEEEEACDDCDCDCBBDDDBD
@5YB
TGGGACTGAAGGACTGCAGCAGTTACAAGAATTTGAAGCTGCCATTAAACAAAGAGATGGCATTATAACCCAGCTCACTGCTAATTTACAACAAGCAAGA
+
CCCFFFFFHHHHHJJIJIJJJJIJJIJJJJJIJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJIJJJJJJJJJHGHHFFFFFFFDEEEEEEDDDDDDDDDD
@5YC
ACCAGATAGCAGCTACCCCATGGACCACAGATTTCGCCGCCAGCTTTCTGAACCCTGTAACTCCTTTCCTCCTTTGCCGACGATGCCAAGGGAAGGACGTC
+
@@CFFFFFAADFHIIIIIIIGGIIIIIDGCCFEGIGIIGGIIIIGGIHIIIGGGIEHHGFHFFFFFFEECCCEDDCDDD@DDDDBBDCDDDDADBD?BD@B
@5YD
AATTAATACCAAAAGTTACCAAAACTGCAGACAAGCATAAAGATGTCATCATCAACCAAGAAGGAGAATATATTAAAATGTTTATGCGCGGTCGGCCAATT
+
CCCFFFFFHHHHHJJGIJJIJJJJJJJJJJIJJJJJJJJJJIJJIJJJJJJJJJIJIJJIJIJJIJJJJJJJHHHHHHHFFFFFBEEDDDD@DDDDDDDDD
@5YE
GCGGCGTCCACTCCATCTGACTCCCTGATTTATGACGACGGCCTCTCAGAGGAGGAGACACCGCTGGTGGACTGTAATAATGCCCCCCTCCCTCGAGCCCT
+
CCCFFFFFHGHGHIJJJJJJJJJIIJIIJIJJIJJGJIIJIGHGFHFEEDFDADDBDDDDDD@BBDD3<BBDDDCDEEEDEDDDDDDDBDDDCDDDDBDDC
@5YF
CCGACGTTGGGGCATTCAGAAAAACAGGCCAGCTATGAACTATGATAAACTTAGCCGTTCACTCCGCTATTACTATGAGAAAGGAATTATGCAAAAGGTGG
+
CCCFFFFFHHHHHIJJJJJJJJJJJJJJJJIJJJJIJJJIJJJJJJJJIJJJJJIJJJHHFHFFFFDDDDDEDDEED:ACDDDDDDDDDEDDEDDDDD@CD
@5YG
CCTCTATTGAGCTGCTGGCCCGCTCATTGCCAAAAATTCACCGCAGTGCATCAGAACCCTCCTTGAATCGGGCTGGTTTCCAAACAGAGGATTTTAGTCT
+
@@CFFFFFHHHHHJIJIIJIJJIJJJJJIJJJJJJJJJGHJJJJJJHHIIIJJJJIJJHHHFFFFFEEEEDDDDBD9@BCDEDDDDDDDDADDDDEDCCD
@5YH
CAAGTTTCATTGAGATGTAGAGAGCTAGAAATCATTATTAACCACAACAGGGCAGAAAATGTACAGTCATGTGATACTCAAGTAAGCTCTTTATTAGATGG
+
@@@FDDFEHHGHDEIIIEFHGGJJJIJIGGGCFDHGIGHGHFHIJGGJIIIGHIIJJGIGIHHIIIJIJJIEHIIGHHHFFHEEEFFFEDEEDEEDEDDDD
@5YI
CAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTTATGGGCAGG
+
C@CFFFFDHHHHHJIHIJJJJIJJJJIJJJJJJJJGJJIIJIJJJFJJJIIJFIFFGGIJGIIHFFFDECDDBDDDDDCDDDDEDDD39@BDDDDDDDDDD
@5YJ
TTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGC
+
CCCFFFFFHHGGGJJIIJJJJJIJJIJGGIIJJJJIJJIJJJJJIJIJJJIJJJJJJJJIJJJHHHHHFFFFFFECEEEEDDDCDDDBDDDDDDBDDDDDD
@5YK
TACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJIJJJJJJJJJJJJJIJJJIJGHIIJJHHHHHDEFFFEEEEEEDDDDDDDDDDDDDDDEDDDDDDDDDDDDDDDDD
@5YL
AGAGGAGTATGCTTGCCTTCTCAAAGTAAAAGATGATTTAGAAGACAGTAAAAATAAACAGGAATTAGAGTATAAAAGTAAACTTAAAGCACTTAATGA
+
=?8BBD7DAFD<FDHI@EHHIII@FE2<F?H?GHCBGGAD>?DGEAGC?<DFDBBBDD?BBCCGCDHGA=8=7@CG@CHHECAEEEED;;;;;@;6>(5
@5YM
AGATCGACGTGCTGAGACATTCTTCTGATAAAGTATCTAAACTAGAAGGTCAAGTAGAATCTTATAAAAAGAAGCTAGAAGACCTTGGTGATTTAAGGCGG
+
@<@DDBBD8<???<CCAC?EFGHGI<F>BFFFAF9CBFDHHGCFFGF<;/??FD=BBBDCH@FGGICG>GEEHBH7A3@C);@C@>@3(5>>@AC>>@C@>
@5YN
GCCTTTCTGGGTTGGGGAGAGGAAAGGTAAGTGGAAAAAACCTGAGAACTTCCTGATCTCTCTCGCTGTGAGACATGTCTGAGACTCCTGCTCAGTGTAGC
+
?1?ADDBDDD><DDFBD<FEEE>3CB;*?BE:9DBDGIIIIIIFEFFF9CCA;.7=>A;C@D@78=@<3>>ABABB:,5>:>>ABBBB@>(:@AA:@BAAB
@5YO
CAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGC
+
@@@DDDDFHHHHFIJGHHIJJJIIIJGHGEHCHGIIJJJIIIJJJIJJIIIJHGIJJJJJGIJIJIGHEHHHFFFFFFC?C>BDDDDDEEDCDCDCACD
@5YP
CGACGTTGGGGCATTCAGAAAAACAGGCCAGCTATGAACTATGATAAACTTAGCCGTTCACTCCGCTATTACTATGAGAAAGGAATTATGCAAAAGGTG
+
@@@DDFFDFGFFFHIHIIJJJJJJIJIGHGHGEHJGIJJIJIIIGIJJGGIJJIIGHHHJJHHHEDDCDCEEEDEDDCDDCCDDDDDCDDDEDDDDD>C
@5YQ
GAAAATATGACTGTTGGAGAAGAAAGTAAGCAAGAACAGTTGATTTTGGATCACTTACCATCTGTAACAAAGGAATCATCACTTAGAGCAACTCAACCA
+
=<=AAAA,,2?<@@<>ABAC9733A+2@<C=CB;AB>?)?A4:74=4*=*=*9>?AB?=)=.)=.=AAA>2>>AB3=A))7>?);>?@>;;@9;;;(,8
@5YR
AGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGC
+
@?@DD?DDDBFFHE9CG@?FHGDBB?FDFECHGIIADBDGDH?G;86BGDEIIID4=;B;@@B5?A9A?;C>C;C@(;;6==CA;5:>C9C5:@C:@@D:C
@5YS
CATGCAGAATGCCACCAAGTATGGCAACATGACAGAGGACCATGTGATGCACCTGCTCCAGAATGCTGACCCCCTGAAGGTGTACCCGCCACTGAAGGGG
+
CCCFFFFFHHHHHIJJJJJHIJIJJJJJJJGJJJJIGGIJJJGIGGIFHGIHIIIIGJJJJJIJJJJIGEHHHHFFFEEE6>>CCCDBDDDDCDCCDDDD
@5YT
TTTAATTATGAGGAGAGAACTCAGCGACACTACCTGGGCCATACAGACTGTGTGAAATGCCTTGCTATACATCCTGACAAAATTAGGATTGCAACTGGAC
+
CCCFFFFFHHGGGJJIJIIJJJJJJIIJJIJJIJJJJJJJJJJJJJIJJJJJCHIIJIJIJJHHHHHHFFFFFFEEEEEEDDDDDDDDDDDDDDDDDDDD
@5YU
CCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTTATGGG
+
C@@FFFFDHHHHHIJGJIGIJJJIIIJJJJJJJJJJJJJJJJGIIJJIJIJIJJJJIIGIJGHHHHHFFDDDDDDDDDDDBDCDDCDEDBD9<BDDCDDDD
@5YV
CAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCG
+
<@@FDBEDFFHHHJJJJJJIJGJJJJJJJCFGIHGEEHGIGGCHGGIIIEHII;CGHGIGHEGHJGDH@HDBBC?C@CACDDDB==B<BAABCCCDDDEED
@5YW
AGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACT
+
CCCFFFFEHHHGHJJJJJJJIIIJJJJJEGGIIIJJJJJJIIJJJJIIJIJIIIGGIEGGHIHHGHH=BDFFFFEDEEDDCDDDDDBCBDBA?BDCBDDDD
@5YX
AGGAATTATGCAAAAGGTGGCTGGAGAGAGATATGTCTACAAGTTTGTGTGTGATCCAGAAGCCCTTTTCTCCATGGCCTTTCCAGATAATCAGCGTCCAC
+
CCCFFFFFHHHHHJJJJAFHIIJJJIJJIIIIIJJIIJJJJJJJJJJEHGHHIJJJJJIJJJJJJJJJJJHHHHGHFFFFFEEEEEEDDDDDDCDDBDDDD
@5YY
CACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATG
+
:?;DDD<DDFFFF<GB<BI<:CFEI;+AB>BFG:F:D?))/7BBFFFA8)=F=FE;DEBEDDBCC;;(5=3?,:><:>ABB@:A9>2??1<<0<B<?AB3:
@5YZ
CTTACCATCTGTAACAAAGGAATCATCACTTAGAGCAACTCAACCAAGTGAAAATGATAAACTTCAGAAAGAACTCAATGTACTTAAATCAGAACAGAATG
+
CC@FFFFFFBHHHJIJGIIJJJJJJJJIJJIGHIJGGGGIJJIIIIIIHIGIIIIJJIJIJJJJIIIEGIJIGGHIEHHEAEHEFFFFFDCEEDEEDDDDD
@5Z0
CTCAAGGATATGCACAGACCACCCAGCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACT
+
CCCFFFFFHHHGHJJJIJIJJJIJIJIJJJIJJIJJIIJJJJJJJJJIIJJIIJJIIIJJJJIJJHHHFFFFFCCCEEEEDDDCCDDDDDDDDDDDDDDDD
@5Z1
TCCCACCAAAAGCATAAAACGACCATCACCAGCTGAAAAGTCACATAATTCTTGGGAAAATTCAGATGATAGCCGTAATAAATTGTCGAAAATACCTTCA
+
@CCFFFFFHGHHHJJJJIIJJJJIJIJIIJIIJIIIIJJJDGIJJJJIJIJJGIIIIIIJJJJHEHFHGHFFFFFACDBFDDEEDADDDDDDCCDDDDDD
@5Z2
CCTTTCATTCCAACAACCCCCAAATTGTAAATCCTCTCAACCATCTCATGCCGGATGCTTCCACAAATCACGAAAATATTTGTTTAACCCATTTAACATT
+
7(((2..)))9))):;(-(3(((...))))2)2))..)))).())))<)0)05''''().:)8.).63))),9'',((((,(,(((,,(,(+((+++(+(
@5Z3
GGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGAT
+
B@?DD?DDHHHGGGIGJGHGIGHGIGHGGJJJJJIIJIHIJJJJGIJIJJIJGFHGIHGFFDEEDDDDDDDDDCDEDCDDDCBDDDDBDBBBDDCDDDCBD
@5Z4
CAGTAAGGTACGGAGTAACTGTCCAAAAGCCATGAAGAGATTAATGGCAGAGTGCCTCAAAAAGAAAAGAGATGAGAGACCACTCTTTCCCCAAATTCTCG
+
==++?AA82<A<77A27A=@ABABCBBCA>AAAABBAA9?>?<A<A>A>A<=9>>BBBAABBBAAB>;>1)>;.7>;;;(5;=-;??????====???>38
@5Z5
CGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCT
+
CC@FFFFFHHGHHJJJJJJIJJHHJJJJJIIGHIJJJIJGGIGIIJJIJJJJJJJGGIJJJJJJIJHHHHHHFFFFDDDDDDDDDDDDDDDDCDDDDDDDD
@5Z6
CAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCC
+
CCCFFFFFHHHHHJIJJIJJJJJHJJJJJJJJJJJJJJIJJJJJIJJJJJJJHHHHEFFFFFFEEEEEEEDDDDDDACDDDDDDDDDDDDDDDDDDDDDDD
@5Z7
GACATGTAGTAAGCCTATACAAGCTCTTCAACAAATAATGACCCAACAATCACATGACTAAGATAAAGTAAAACCGAGACAATGACCCATAAATGAGAACC
+
(;;(()))))2.2;)6)9)2)))2)))3.=:))(.)2=@8?3;33(((()6=)3)910/)))//..))./66))('''',(.(..(-6((5;((((,,2(7
@5Z8
GTGAAAATGAAAAGTTCTGTCTTTGATGAAGACAAAACTTTTGTAGCAGAAACATTGGAAATGGGTGAGGTTGTTGAAAAGGATACAACAGAACTCATGG
+
BB@DFFFFHHHHHJBGIIJIJJJJIIJJIJJIHHJIGIJIJJIIIGIJIJJJFJJJJIIJIIIJJGGEIICHHIHFDHGHFFF>CCEE@B@DDDDDDDDD
@5Z9
AAAAATTCGATGGAGACATCAAACAAGAGCCAGGAATGTATCGGGAAGGACCCACATACCAACGGCGAGGATCACTTCAGCTCTGGCAGTTTTTGGTAGCT
+
@+=DDFFFHHHHHIIIIIIIIIIIAHIIIIIIIIIIHIGGGHIIIIIIIIIIIIIIIIIHHHHFFCCCCBCCCBCCCCCCCCCCCCCCC<CDCCCCBCCC@
@5ZA
CCACACCATCCAGCACGCCAGTGTCCCCACTGCATCATGCATCTCCAAACTCAACTCATACACCGAAACCTGACCGGGCCTTCCCAGCTCACCTCCCTCC
+
@<<DDDD<DFBF<AFG?@CGFACCEGGDHD@CDDDHBFEIGGHDFGDGCH@DGHHDHEGHG>DHABB>DCCCCCCBB??BBCCCCA@A(:>>A4<ABCCB
@5ZB
CTATGCTAAACTTAGCCGTTCACTCCGCTATTACTATGAGAAAGGAATTATGCAAAAGGCGGCTGGAGAGAGATATGTCTACAAGTTTGTGTGTGATCCA
+
=<=1<+<,@AAB>AA4AC<)?ABB<=<))@ABB=<<**:4::7=>B>AB4*/*/88771(-4',39=;?8;==9=>:=3;(3::833:(+38(2888::;
@5ZC
CTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGC
+
CCCFFFFFHHHHGGGGIIIJJJIJJJJJJJJJGGJIJIJJJJJJIJJGHIIJFIIFHGIIJJHGFFEEEECEDDDDDDDDDDDCDDDEDDD:@CCDDDDCD
@5ZD
CCAGCAGAAGGTGAACTTTGTCCCTCCCCATCCATCCTCCATGCCTGTCACTTCCTCCAGCTTCTTTGGAGCCGCATCACAATACTGGACCTCCCCCACGG
+
C@@DFEDDHHHHDEHIIJJIFFGIGFGIIJJFHGGIIJJIIGGIIBGHHHJIIIJEHGIGGIIGGHGJIHHI=EEFDCCCDDDDDDEDDDDDDDDBDBDD@
@5ZE
CAGCTCCAAGAAGAAACATTCAGACTAGAAGCAGCCAAAGATGATTATCGAATACGTTGTGAAGAGTTAGAAAAGGAGATCTCTGAACTTCGGCAACAGA
+
??@DAD>?AFFBDHC?>D>H,3A4ABHCEH@GI@@?DB3CDFGB?B*B*0)?DGE=8=;-;@G@GCHGGI@=C;A72;B@@;666>6;>AA@?=:?@?@3
@5ZF
GGAGTCGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTT
+
:++44208D8@<A?<A+AEB?C0CD08@)/?@8B8;;A@C@=765-:4,??>39855;;555>(5:>A>::<<2+:(39:0509588>9???>>A(4::>
@5ZG
GCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACC
+
CCCFFFFFHHHHFIJJIJIJJJJJJJIJJJJJIJJIIJJJIJJIJJJGJJJJJJJJIJJIJIJJFHGHGFFFFEECDDEEDDDDCEDDDDDDDBDDDDDD
@5ZH
GCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCC
+
@CCFFFFFDHBHHGGEBFGHGGIDHEHIJGGIGGIIJIIJJJIIHJIIIIJJIJGHFEHEFFFFFEEEEEEDDCC>CCDCCCCBDDB9@BCDDDDDDBBB
@5ZI
GGGAAAGCGAGAGGGAGACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGG
+
@@<DFFFFDDFDHGHGH>EHGGIJIIJIJEHHHFF@FH8DG=>CH>D=?AA@ACCCBB;@BDDBB7@B@CDD>CC@>@CCDCDCCDDCCDCCCBDDDBDBA
@5ZJ
GACCACCCACCTGCAGTGTACCGCCGGAAGCACCAGGAGCTGCAAGCCATGCAGATGGAGCTGCAGAGCCCTGAGTACAAGCTGAGCAAGCTCCGCACCTC
+
@C@FFFD>FFHHHJIFFGEHHGHJJIGGGGIJEIJJJIIII@GCHGFHDEHFEF@CCCECCACCDDDBDDDCBDD5@CCC>ACCCBDDCDD>CD<@DDDDB
@5ZK
CCAACAATGAGCAACTGCCCATGCTGGGCCGGCGCCCTGGGGCCCCGGAGAGCAAGTGCAGCCGCGGAGCCCTGTACACAGGCTTTTCCATCCTGGTGACT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJIJJIJJJJIIJJJJJHHHFFDDDDDDDDDDCDDDDDDDDDDDDDDDDDCDDEDDDDDDDDDDDDEDDDDDCCDDD
@5ZL
CCGGGCCTTCCCAGCTCACCTCCCTCCATCGCAGTCCATACCAGATAGCAGCTACCCCATGGACCACAGATTTCGCCGCCAGCTTTCTGAACCCTGTAACT
+
CCCFFFFFGFHHGJJJIJIEIGIJGHGJIJGIJJFHIJJJJJIJEGIEHGIJIHIJJJJAEHHEFFFFCDCEEE?BDDDDDDDDDDDDDEDDDDDCCCEDD
@5ZM
CTGTCCATATCCTAGGCTGGGCTGGTTGTAACCCCCTGTGCTAGATTGAGGTTGACTAGTCTCAGTGGGCTTGTTTCCATCCTGCGGTCTTGTAGGTGC
+
CCCFFFFFHHHHHJJJJJJJJJJJJGIJJJJJJJJJJJJJIJIJIIJJIIJFHIHIJJIIIJJIJGIHHHHFFFFEEEEEEECDDDD?BDDDCDDDACC
@5ZN
CCTGAAGCAGGTCAACCACCCACATGTCATCAAATTGTATGGGGCCTGCAGCCAGGATGGCCCGCTCCTCCTCATCGTGGAGTACGCCAAATACGGCTCCC
+
CCCFFFFFHHHBFHJJJIJJJJJJJJJJIIJIIIIIJFGIJJJJIJJJJJJIJJJJIJIJJJGHFFDDCDDDDDDDDDDDBDCDDDDDDDDDDDDDB@BDD
@5ZO
CACCAGAACATTGTTCGCTGCATTGGGGTGAGCCTGCAATCCCTGCCCCGGTTCATCCTGCTGGAGCTCATGGCGGGGGGGGGCCCCAAGGCCCTCCTCCC
+
@@CFFFFFFDHHHHIIJJIJDHGJJJIJDHIJJJJIIIIGGIIJGIJJJGGHHFFFFDFEEEDEEDDDDDDDC@BD5<BD-9&&&&)(+(((8(+(2(++(
@5ZP
CGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTT
+
CCCFFDFFGHHHHJGIJJJJJIJGGIGGIIIIJJJJIIIIJJJIJGIIHIIIGHIIJJJHFFHFFFFFDDDCEDDCDCCDCDDDD=BDDDDCDDDD>CDDD
@5ZQ
ACGAAGAAAAATAATAGCAGCAACAGCAATGTGAGCAAGAAGGAGCCAGCGCCCATGAAGAGCAAGCCCCCTCCCACGTATGAGTCGGAGGAAGAGGACA
+
CCBFFFFDHGHHHJJIIJJIJJJJIIHIIIJFFIEHHIIJCGGJJIIIIJIIJIJJIEIEHHHHFFFFDDDDDDDDBDBDDDDCCCBBBDDDDD@?B?BC
@5ZR
AGAAATACTTATAGAGGAAAATGAGGACCTCAAACAACAATGTATTCAGCTAAATGAAGAGATTGAAAAGCAAAGGAACACTTTTTCATTTGCTGAAAAA
+
@@@?BD>DFFFF8FEE;3C?:F<FA?++ABEEFCEFFFIFEGIIFEDFFCFDFFB@BBBFCFEI>EFFGF9@DE;=CEA@B;?@@BC@AADBABAABBBB
@5ZS
CACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACC
+
CCCFFFFFHHHHGJJIJJJIHIJJIJIJJJJJIJJJJEIIJIJIJHJIIHIGIIJJJJJIIIJJJJHGHHHFBDDCDBBBBDCDCDDEEEEECDBDDBDDD
@5ZT
CTTGGGAAAATTCAGATGATAGCCGTAATAAATTGTCGAAAATACCTTCAACACCCAAATTAATACCAAAAGTTACCAAAACTGCAGACAAGCATAA
+
CCCFFFFFHHHHHJJHJJIJJJJJJJJJJJJJJJJHIJJJJJJJJJJJJJJJJJJJJJJJJJJIJJHHHHFFDDFFEEEDDDDDDDDDDDDDDDDDD
@5ZU
GGAGGATCAACCACAGGTTTGTCTGCTACCCCCCCTGCCTCATTACCTGGCTCACTAACTAACGTGAAAGCCTTACAGAAATCTCCAGGACCTCAGCG
+
8:?BD;DD?DDDD7<EEEB<+A@A?FFIIC@CD@D'7B=)@@;=C=A7A>DDAC=;77?AD@@?6=??AAA?AA>A:::A>A<A4>4>>18<9>AAA>
@5ZV
ATCGAATACGTTGTGAAGAGTTAGAAAAGGAGATCTCTGAACTTCGGCAACAGAATGATGAACTGACCACTTTGGCAGATGAAGCTCAGTCTCTGAA
+
8:?D?DAAFB<<<2<<AFACHHBE@CBACBGB=D<?F9?9?*??:?@:DHBBBH@78C;7FA;@=C=E==?;@@@B;A=>;>C@>;>>:5>>:::AC
@5ZW
TCCTCCTGGAGCTGCTCTCCGACAGCGCCAACGCCAGCTGTATCACCTGGGAGGGGACCAACGGGGAGTTCAAAATGACGGACCCCGATGAGGTGGCCAGG
+
C@CFFFFFGFHHFGIDIIGJHIJJIIIDHGGIIIIIIJJGIJGIIJIIHHHHFFDDBBD@BDDDDD;@?CCDEDDCDDCDDDDDDDD<BDDDC>BBABDDD
@5ZX
CAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGT
+
@<@DDDADBFHABBFH@BA:AFF@:ABG;<EGIIGI:DFH?F<@BF<76==;C;C@>=AEA<939>((,;555(>?C5>@:::AA@:>48?83:@CC@CC>
@5ZY
AAAAACATGAAATTAGAGCTGACTAATTCTAAGCAAAAAGAAAGACAGTCTTCTGAAGAAATAAAACAGTTAATGGGGACAGTCGAAGAACTTCAGAAG
+
@BBFFFFFGFFHHIJIJIJIGHGHIIHHICHHIEGGIJHIJJJJJIIIHGGFCDDHIGJIG@FIJJJJG@DHI@EEFFFEFB@CACB?B?CDCCDDDDC
@5ZZ
GAAATACTTATAGAGGAAAATGAGGACCTCAAACAACAATGTATTCAGCTAAATGAAGAGATTGAAAAGCAAAGGAACACTTTTTCATTTGCTGAAAAAA
+
;@?7DDADFDFDFGEAGFGHIE@DHEG=GGIFG>DGGCCGGHGIIDHIIIIGGIGGHCIIGHHHGIIIEEHGHCEC@CEDDEFFFCACCDEEB>A@CDDD
@600
CGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTT
+
CCCFFFFFHHHHHJJJJJJIJJJJIJJJJJJJJJJJFIJJJJJJJJJJIJJJJIJJJJJHHHHFFFFFEEDEEDDDDDDDDDDDD=BCDDDDDDDDCDDDD
@601
TGCAGGAAAAGAAACTCTTTCATCTGCTGCTAAAAGTGGTACAGAAAAAAAGAAAGAAAAACCACAAGGACAGAGAGAAAAAAAAGAGGAATCTCATTCT
+
CCCFFFBDHHHGHIIIJJJJJJJGIJCIIJIJJJJJCGH?FHGGHIIJIJJIJJIJJIJJJHHFDFFFCEEECCCCBBCDDDDDDDDCDDDDDDDDEEEE
@602
CCTGATCTGTCCAAGCCTAAAAACCTTGCTCCTTTACAAGAGAGTCAGGAGTCTTACACAACTGGGACTCCCAAAGCAACATCTTCTCACCAGGGCCTTGG
+
@CCFDFFFHHFHGIJJJJJJIJJJJJJJJIJJJJIJJIJJJIIJDGIJJHJGHHIJGIJIJJIIJJIJEHFFHHFFFFFBCCEEDEDDACBCDD?BDDDDD
@603
CCCGCTCATTGCCAAAAATTCACCGCAGTGCATCAGAACCCTCCTTGAATCGGGCTGGTTTCCAAACAGAGGATTTTAGTCTATATGCTTGTGCTTCTCC
+
CCCFFFFFHGHHHIJIIIIIBDHIIJJJGIIIJIIDGIFIIJJIJJJIJGCCGBA<EB7@BBEECECEDACDADDDDC95@ACDCDCCDEDBCDDDDDDD
@604
CTATGTCCTATGAGGAGAAGCGGCAGCTCAGCTTGGACATCAACAAGCTCCCCGGCGAGAAGCTGGGCCGCGTGGTGCACATCATCCAGTCACGGGAGCCC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJIJJJJJJJJJHIJIJJJIIJJIJJJJJJHFDDDBDDDDDDDBDDBB9BD?BDDDDDDDDDDDDDDCDDDDDBBDD
@605
AGAGGACAAGTGCAAGCCTATGTCCTATGAGGAGAAGCGGCAGCTCAGCTTGGACATCAACAAGCTCCCCGGCGAGAAGCTGGG
+
CCCFFFDFHHHDHDEFGHGHIJHIGIIIJFIJIIIJFDGJJEGGGEEFGIGIG@DHIGHHGEEFFFDEDCDBB@D@>BDCCDCB
@606
CTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTC
+
CCCFFFFFHHHHHJJJJHIJJJJJJJIJJJJJJJJJJDHIJJJIJJJJJJJJJJJJJJJJJJIJGIIJJHHGHHFFFFFEEDEEEDDDDDDDDDDDCDDDE
@607
CAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGG
+
CCCFFFFFHHHHHJJJJJJJIIJJJJJJIIIIHIIIJIIJIJIIJJJJJJIIJJJJJJJJJJHHHHFFFFFACEEFECEDDDDDDDDDDDCDBDDDDDDDD
@608
AAACTCTAATAGAAGAGTTAAAAACTTTGAAGGATCTTTATTCCAATAAAAGTGTTTGATTCCTAAGAAAGAAAATATTTTTGTGGACATGCATAAAAATT
+
CCCFFFFFGHHGHJJJJHJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJHHIIJIIJJIIIJJIJJJJJJJJIJJJJJHGEHFFFFFEEEEEEDDDDD
@609
GAGGGGAAGGCCTGCTCCCAGTTCGGTGGATGGCTCCAGAAAGTTTGATGGATGGAATCTTCACTACTCAATCTGATGTATGGTCTTTTGGAATTCTGATT
+
?<<D?D:DHDDDHG@BGDFDEHEH@::??B<BGEEG@FHIIGGFHGICF@FG>DADGIFHCHHHE>??DECC>>C;@C;CBDC5>;:A::;CCCCCEECEC
@60A
CTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTC
+
CCCFFFFFHHGHHIJJIGGHIIJJJJHHIIIJJJJJG?FHIJIJIFIIIIIJIJIIJJIIJJIIGHIIIGHFHHDFFFFEEEEEEDDDDDDDDDDDDDDDE
@60B
CTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGATCAACAAAGCAGCTATGGGCAGCAGCCTCGCACTAGTTACCCACCCCAAACTGGATCCT
+
<8;?;1.()2.>((283;343@<))):13.0)<)..)<=<=).9=>5>>().<1=;?1=6((6-:;(9/90'','88(7:=23((,5&0(++(+5//6((+
@60C
AGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAA
+
@@@DFFFFFHFBHGIIIIIIJIIGGGEGIHGIIHIGHGIIIIGEHHIGAFGIFHHGFEFDEEEDCDDDCDDEDDCDDDDDDDDDDBDDDDEDDDDDDDD
@60D
GGAGTAACTGTCCAAAAGCCATGAAGAGATTAATGGCAGAGTGCCTCAAAAAGAAAAGAGATGAGAGACCACTCTTTCCCCAAATTCTCGCCTCTATTG
+
?<@F?DDDADBFFGHEBHCGCEHGGHIFIGCEGBCFEGAHI?DHHIGHIIIGGGIIEH?GIG=FHIHIGHHHEFDFE?CE>CBACCCCC?1;@=@:>AC
@60E
GGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCAC
+
CCCFFFFFHHHHHJJJJJJIJJJJJJJJJIJJJIJJIJJJJJJJHIJJJJJJJJJJJJJJHHHHHFDDDDDDDDDDDDDDDDDDDDDDCCDDD9BCDDDDD
@60F
AGAGGACAAGTGCAATCCTATGTCCTATGAGGAGAAGCGGCAGCTCAGCTTGGACATCAACAAGCTCCCCGGCGAGAAGCTGGGCCGCGTGGTGAACATC
+
10339.(:((2))2)).).6613;8)84<>.).5<(=9=6(7-<7;;73>?);3>0)..:;?7)().339=''30&&03:</(((+0&&0&0:-(26:(8
@60G
CATGCACCCTCTGATCCTGAACCCCCGGCACTCCGTGGATTTCAAACAGTCCAGGCTCTCCGAGGACGGGCTGCATAGGGAAGGGAAGCCCATCAACCTCT
+
@@@DDDDAFF:<DFGGIFH9EBEBH:@GBAB;BBF8?FCCFIEIEHHGIHIFEHHHEEDEEB>BB6?BBBBBBBCCCCCB?BBBBBBB???BCCCCCBCCC
@60H
CCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGC
+
CCCFFBDFHHHHHHHIIJJIJJJIIJJJIJJJJJJJJJIJJIJJJIJJIJJIJJJJJJIJIJJJJHHHHHHHFFFFFFEDDDDDDDDDDCDDDDDEDDDD
@60I
CATCGAGGCTCGTTGTGAAGCCGAATCGTGCGATGCGATGTGTAGGCCTTGGACGGAGTTAGTGCCGGTTGGTTTAATGGAGGGGAAGACCCGGGACGGGC
+
0--(()((((.5(-)(2))).(-</((.((09(('('6.'.)))).).))))).,3',(-((((,(,')&&&+(((((36(+())&&2((585-)&&0&)&
@60J
GGAGAAGCAGGAGCTGTCGGGAAGATCAGAAGCCAGTCATGGATGACCAGCGCGACCTTATCTCCAACAATGAGCAACTGCCCATGCTGGGCCGGCGCCCT
+
CC@FFFFFHHGGGIJJHIIIJGGGHJJJIJJJIIIJGHGGGJEFGGEHGGGGGBHFDDEDDD>CDDDDDDDDCCCCCDCCCDDDDCDDDDDDB>@B@BBDD
@60K
GGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCT
+
?@@ADDDDHHFFHGBGIIEHGIGGGHHIIIJGHHEEEHHJIEGGGIGGIIIHJJJJ3BHHEGIG<=EEHHFDFBDECECBBAB5@CCDDCDDD?BDDDDDD
@60L
CTCCGCTATTACTATGAGAAAGGAATTATGCAAAAGGTGGCTGGAGAGAGATATGTCTACAAGTTTGTGTGTGATCCAGAAGCCCTTTTCTCCATGGCCTT
+
=:?DD?@?FBDFD>C?FH?CBF@?FEHCH@FEFFHCH:CG??DD@FCB(77==<.88=@@=@DGEGI.=CEHD;@CEECCCCCB@?CA>>ACCACCAB>@C
@60M
CAGAAGGCTGTATGTTTGAAAAGGGCCCCAGGCAGTTTTATGATGACACCTGTGTTGTCCCAGAAAAATTCGATGGAGACATCAAACAAGAGCCAGGAATG
+
CCCFFFFFHGHHHIIIJJIJJJJJJJJJJJJJIJJHIJJJJJJJJJIJJJIIGGIIIIJJJJJGHJHHHHFFFFFDDEEDDDDDDDDDDCCDDDDDDDDDD
@60N
GAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCAC
+
BBBFFFFDHHDFHEHHIFHGIIJJJJJIJJJJJJJJJHJJJJJJJJJJJJJHHHHHFFFFFEEEDDDDDBDDDDDDDDDDBCDEDDDDDDDDDDDDDDDDD
@60O
CTCTATTAGATCACATATACGCTACGAAGAGTGAGGTTTGGCCGTATGGGGTCTTCATGTGAGAGCGGGTGAGGCCAAGGGGTGACCGGTGGTCTGGGGTT
+
-((-2)2.9))):))2)2)3((:(2-2(1(2=)887<(.(77)(0((<5(-5'.)).)..)).))('',,'(,(((,(++()&&(+()0&&&&+++(()&&
@60P
AGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACC
+
??+AD?=22:C@DCACED?F<?C<??<D9@B<*?BD9;8@<D8D>DA@ADDIDC>DD2@@A(6@;@@>-;>;=?852<??12<<39>>8::A3>AA>9(+8
@60Q
CACATGTTGGAGCGCCCCGTGCCCCGCGCGCGGGAGTGGAGGCAGGGGCGGCACGTGAGGAAGGGGGGTTACTCTTCCTGCCGCAGGTCCGGCCGGGGGGG
+
10355)222()))((2:<((1(<<1((('''-'',',(((((((+&)5&&5&&)&+(288:(((&0&&))++((++2+(((+&&&&)((+&&))&&&&0&)
@60R
CTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTAT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJBHIJJJJJJJHCEHHHFFFFFFEEEEDDDDDDDDDDDEDDDDDDDDDDDDDDDDDDDDDD
@60S
CTCAAAAAGAAAAGAGATGAGAGACCACTCTTTCCCCAAATTCTCGCCTCTATTGAGCTGCTGGCCCGCTCATTGCCAAAAATTCACCGCAGTGCATC
+
@@<D;DD?D?F;F>:CFFCDGAC8CEG8CDFEE9?D9DDDE<BFEGDD:FBEGE@==7@=DD=CEHH><3>BCC>>@CCCBBBCCCCC?55<B@C>@>
@60T
GGAGAATATATTAAAATGTTTATGCGCGGTCGGCCAATTACCATGTTCATTCCTTCCGATGTTGACAACTATGATGACATCAGAACGGAACTGCCTCCTG
+
@@@DDFFFGFHHHJIIJJHEHIJJJJGJJDDGIIIIGIEGICGHIHIIGHIHHDHGGHH?D9;CDCEEDEC;C@ACDDDDCDDCCCBDDBDDDDDDDDDC
@60U
GTTGTGATGGCCCAGGTTCTTCAAAAGATAGATCCTGCATATTTTGATGAAAATTGGCTAAACAGAATCAAAACTGAAGTAGGAGATAATTGGAGGCTAA
+
@@BFDDFFHFFFHIJJFHGIJGGHJHIJJICDGHGIGJJIJIJJJJJJIHHIJIJHHIHIJIIIGHEHIJJJJIJGHEECADFC@BCEEEECACDBDDDD
@60V
GTGAAAATGAAAAGTTCTGTCTTTGATGAAGACAAAACTTTTGTAGCAGAAACATTGGAAATGGGTGAGGTTGTTGAAAAGGATACAACAGAACTCATGG
+
@@@DFFFDHHGHHIIJJIJJJJIJJJJJJJFIJIJJIIGJIIIBFHGIIIJJJJIJIGIJJJIIJBBHGICGHIHFFHHGDEFDEEEEEDDCDCDDDDDD
@60W
TGAGAAAGGAATTATGCAAAAGGTGGCTGGAGAGAGATATGTCTACAAGTTTGTGTGTGATCCAGAAGCCCTTTTCTCCATGGCCTTTCCAGATAATCAGC
+
CCCFFFFFHHHHHJJJJJJJJJJAGHIJJJJJIJIIJJJJJIJJJJJIJJJJJFHHIIIJJJJJJJJJJHHHHHFFFFFFEDEEEEDDDDEDDDDDDDDDD
@60X
AGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGC
+
@@@DFFFFHHHHHHJGHIIIIJJGIIFHGHGIJJIGIJJJIJIJJJIJIGIJHHHHGFFEEFFEEEEEDDDEDDDDDDD>CCDDDDDBBD@CDDDBBCDD
@60Y
AGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCT
+
@C@FFFFDGFHFBGHGEGIJEHIIIGIJCHIHBFDGHECHIIIGIBFCHIEIIJCHGA?D@GHGC;AA??3??DBDEECA@BBBDDCCCDDDDCACAC@BC
@60Z
GGCCGCACCAGGAGAACAACCACCAGGAGTCCTACCCTCTGTCAGTGTCTCCCATGGAGAATAATCACTGCCCAGCGTCCTCCGAGTCCCACCCGAAGCC
+
@@@FDADFGHFHGIGEGEG?FGHIIIGIIIEHIHGIGEGEGFGGHB@HAHGGIGGIJHGHHFFFFFFF@EAEBEAB8?@BDDDDDDDDDDCDDDDDD<>A
@610
CCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAG
+
1=?DBD>A32AFFB:C?A3A?FFDB?+CEF?C@?@G>B9?*0??9B?FICFID@FDF<;7FF9CCEA@C)77.?DD7;;@8,;@;9<BBBAB3@:8??8
@611
TTTAAATTCAGCTATGGAGAAAAGTGCCTGTACAATGTCAGTGCCTATGATCAGAAGCCACAAGTGGGAATGAGGCCCTCCAACCCCCCCACACCATCC
+
CCCFFFFFHHHHHJJJJIJJJJJJHJJJJJJJJJJJIJJJJJIJJJJJJJIJJJJJJJJJJJJJGHIIIJIHIJJJHHGHFFFFDDDDDDBDDDDDDDD
@612
GCCAAGGGAAGGACGTCCTATGTACCAACGCCAGATGTCTGAGCCAAACATCCCCTTCCCACCACAAGGCTTTAAGCAGGAG
+
@@@DD<B?F>FDDAAHIIIIEHGDECCGHCGAEFFIIHIGAHHGHHIG=FGCHIIIIHHCABBB2?BACBCCCCCCCCCB1<
@613
CAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGC
+
@??DDFDEDFHH?G@FHGHHIIDCHIIEGHI>FGHBGHGGIIIIIGIIIEHIIIIIIIIEHHEGACAHHGCEDFFFD>A=B>BBDDCDCACC;ADCACC
@614
CTGCAATCCCTGCCCCGGTTCATCCTGCTGGAGCTCATGGCGGGGGGGGACCCCAAATTCTTCCCCCGGGAGACCCCCCCCCGCCCCGGGCAGCCCCCCCC
+
@<@;?DDFBH>DFD=EBGECBEAHGGDGGCG>FGGGGIII@FG'35575-&2((+2+((+(+(3+(0&00&&&(+22&&)&&&&)0&)&)&)0(28&)))0
@615
GCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAA
+
CCCFFFFDFHHHGGGIGGJIIJDHHIIJJJIIIIJGHHIIIGDFDGIGGGHGGGIIIIHEHHEHHHFEFFFECCEDBDDDDDCDBDDDEEDDDDBDDDDD
@616
AGCCAAGCTTGCCCAGTTTCGACAAAGAAAAGCTCAGTCGGATGGGCAGAGTCCTTCCAAGAAGCAGAAAAAAAAGAGAAAAACGTCAAGCAGTAAACATG
+
CCCFFFFFHHHHHJJJIJJJJIJJJJJJJJJJIJJJJIJJJIIJJJJJIJJFHJJJJJHHHHHFFFFFEEEEDDDDBCDDDDDDDADDDDDDDDDDDDDDD
@617
GCTGATAGGACTTCAGAGGCTCTGCCCCTTTGTTGGCAGGGAGGCTTCCAGCCTGAGAGCACTCCCAGTTTGGATGCTGGACTTGCAGAGCTGGCTCCTCT
+
@CCFDFFEGFHHHIIIGGHIIGIIIJGIIGHIHIJJJEGHJGJIGIIGGIDFGHGGGHJIHHHHGFFFCDECC;ACBACDBACDDDDDA?CACDBCDDDDD
@618
ATGCAAATTAGTTTCTTGCAAGAGAAAATTAAAGTATATGAAATGGAACAAGATAAAAAAGTAGAAAACTCAAATAAAGAAGAAATACAGGAAAAGGAGAC
+
CCCFFBDDHHDFHJJJJJIJJJJJFIJJJJJJJJFHIIJJJIJJJJGGHJJJIIIIJJIJI@GHIJJIGIIJJHHHHHHFFFFFDCECEEDDDDDDDDDDD
@619
GGGAAAGCGAGAGGGAGACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGG
+
?@@D;DA>DF??8?:CF:F@:C?:?DBFE=A;?=;65A5@B;6A=BBBC@AA@(;;;?B@B7:8B>>@::@B:@ABA44>:@A@9?@BB<99(095>3?88
@61A
CACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCC
+
?@@BBDDBCFHFFGBHGIGIGIIIIIIEDDBFHGIGBGGGIIGGIIGHHACDBB@@DHGEHGA@EDHGDFFHEHEDBB?AAAAA?AC?BBBBBBBB?BBB
@61B
CTCCATTTATATGAGGCAAGAAGGCTTCCTGGCTCATCCCAGCAGAACAGAAGGCTGTATGTTTGAAAAGGGCCCCAGGCAGTTTTATGATGACACCTGTG
+
1??DDDDAAFBDC4CDGFCF@FFCEIDFEABFGFFFIIFCDGIE?;DGFFEBF;CFFFEFF@C;F4)7=@;;15,9=?C@?BBBAB:AB>D3;:55,5>BB
@61C
CCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGAC
+
@@@FFBDFHHGAHGIGIJJJGGGHICFFHIIIGIIJJADDGGGCDB<BFHCEIJIIIJICHHAHIGHE?EHFDFFDDB>@BDD?ACDCCCDEDDD<BDDBD
@61D
CTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATG
+
CCCFFFFFHHHHHJJJIJIJJJJJJJJJJJJJJJIIBGHIIJJJJJJJJIIJIIJIJJJJHHHHEEFFFDDDDDDBCCCDACDDDDDDDCDDDDDDD<BCD
@61E
CCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCC
+
CCCFFFFFDHHFHIHGIJGJIJIIFHIGIHEGIIIEEHIGHIEDHHIJJJFIFGGGGGIJIJGHHFFFFFCCDCCDDDDDDECDD@BBDDDDDDDDDCCAC
@61F
ATCAAACTTATAGATATTGCACGACAGACTGCACAGGGCATGGATTACTTACACGCCAAGTCAATCATCCACAGAGACCTCAAGAGTAATAATATATTTCT
+
CCCFFFFFHHHHHJIJJIIJJJJGIJJJJGIJJIJJIJJJGHIGIIJJIJJJJJIJGIIJDEHHHGHEFFFFFEEEEDDDCCDDDD>CDEEDEEFEEEEEE
@61G
GACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTG
+
CCCFFFFFHHHHHJJJJIJJJEIJIIIHIIJJIJJIJJHIIJJJJIIJJJJJJJIJJIHHHHHGFFFFFEEEEEEDDDDDDDDDDDDDDDDDDCDDD@BDD
@61H
TGGCTCACTAACTAACGTGAAAGCCTTACAGAAATCTCCAGGACCTCAGCGAGAAAGGAAGTCATCTTCATCCTCAGAAGACAGGAATCGAATGAAAACAC
+
@C@FFFFFHHHGHIIJIFGHIIIJIJIHIJJIJJJGIJJIIIJJGIJIIIIJIJJIIJGIJGIHHHHHGHFFFFFFCEEEDEDDDDDDDDDDDDDDDDDDD
@61I
ACTGTGTGAAATGCCTTGCTATACATCCTGACAAAATTAGGATTGCAACTGGACAGATAGCTGGCGTGGATAAAGATGGAAGGGTGAGTGGCATAGTGTT
+
@BBFDDADFFFHHJJJJJJJIIIIGHJIIJJJGIJIGJJJCDGHIIIGGGHIGEHGHHIJIGIGFH@BHEEEHEDFBDFFCEDD2=?B;>?@C>CC5>CF
@61J
CTGCTACCCCCCCTGCCTCATTACCTGGCTCACTAACTAACGTGAAAGCCTTACAGAAATCTCCAGGACCTCAGCGAGAAAGGAAGTCATCTTCATCCTC
+
CCCFFFFFHHHHHJJIJJJIJIJJIIJJJJJJJJJIJJIIJIJJJJJJIJJHHHFHHFFFFEFEEECDBDDDDDDDDDBDDDDDDDCDEEDDDEEEEDDD
@61K
TGGAAATGGGTGAGGTTGTTGAAAAGGATACAACAGAACTCATGGAAAAACTTGAGGTAACCAAGCGAGAGAAATTAGAGCTGTCACAGAGACTGTCTGAT
+
@CCDFFFFHHFHHJIFHIGHIJJJIJJJJJJJIGGIJJIJIIJJJJIJIIJIJJJJJFFHIIIIJIHAEBBBEEEEECCCDDDDDDDDDCCCDDDDDCDCD
@61L
GTTCAGCGTAGAGTCGCTGGAGCGGGCGGAGCTGTGCGAGAGCCTCCTCACTTGGATCCAGACATTTAATGTGGATGCACCATGCCAGACCGTGGAAGATT
+
CCCFFFFFFHFHGIIJJJJJJJIJJJJJHFFDEEEDDDDDDDDDCDDDDDDDDDDDDDDDDDDDDDEEECD:CCDCDDDDDDDDDCDDDDDD9ABDDDDCD
@61M
CCAGCCCCCGGCAGGAGAGCACACGCGTGATCCAGCTGATGCCCAGCCCCATCATGCACCCTCTGATCCTGAACCCCCGGCACTCCGTGGATTTCAAAC
+
@@@DDDDDHDDFHGDG=3CBGGIIGGG@FHIIIGIIEGEEEHHEEEDCCCCCC;AACCCCBBB?CCDCCCA@:@?BBBBB@-9399<<?B8>CCCDCCC
@61N
TGGAGATGTTCTTACTGGAGACTCAGGTGGAGTCATGCTTATATGGAGCAAAACTACTGTAGAGCCCACACCTGGGAAAGGACCTAAAGGTGTATATCAA
+
C@CDFFFFHHHHHJJIIIIGIJJIJJJEHIGIHIJJIJJJJJJIJGGGIJJJJJJJJJI=FHJJIIJJJJJHHHHHFFFFEEEDDDDDDD5@:@CDADDD
@61O
CTCCTCTGGCAAGGCTGCAAAGAAACCCACAGCTGCAGAGATCTCTGTTCGAGTCCCTAGAGGGCCGGCCGTGGAAGGGGGACACGTGAATATGGCATTCT
+
CC@FFFFFGHH>FHHIJIIIIJJJGIJJJJFJJIJJIJJIJIIIIHIDHHII>CHIDIIGGGIIGHFDDDDBBBDDCDDDD@@BDD8A?BDDEEDBCCCCD
@61P
ATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCA
+
<@@FDDBFGFDBCEBACEEBBGIIGGDH?@GIGICADGHGI<???8BGE@FH=@EHEHFFFFCCBCCCCCCCC>>@ACCCCBBCCBCCC?<<CC@CC?BA
@61Q
GTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGC
+
@?@FDDF:@@@CFH@FHGIICGGIIIIGE9FG@GGGGHIGIIEHIIFGIIIIHIFGGIGIIBGHFEHFDFFBBECECE>CCCACACADC?CC??CCCCCBB
@61R
CGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGG
+
@@<DD@DDBFB?CEEEBBFHFBCFAFCHE92+A9?EE>GHFDB*?DFEHGIIIBBG6@EEEHDE3?>?2?BB=6;@>AACCAA@35->9A:<:5<:::4:?
@61S
CAAAGACCTACTTTTCATAGAATTCAGGACCAACTTCAGTTATTCAGAAATTTTTTCTTAAATAGCATTTATAAGTCCAGAGATGAAGCAAACAACAGTGG
+
1>=<+<<==AA=@A>7?B>7+>,<+@@@BB=A))1:7=?1:<:?AAB9=<=ABBA:77=87=4>BA4=AB>>7>=BBA;A).7>>?@@@@@>(;=;2;5;:
@61T
CCGGCGCTTTCCCCGCAAGATGGACGGTTTCGCCGGCAGTCTCGATGATAGTATTTCTGCTGCAAGTACTTCTGATGTTCAAGATCGCCTGTCAGCTCTTG
+
@<@FFFFFGHHBAGIGIIIEHHIIFHH@CHIIIGHFFABCDCCCCCDCCDDDEEEDDEDDDD@CDC@CCDEDDDEEDDDEDEDCCCBBBDBDDDDDDDDDD
@61U
TTTTATGGTGGGACGAGGATACCTGTCTCCAGATCTCAGTAAGGTACGGAGTAACTGTCCAAAAGCCATGAAGAGATTAATGGCAGAGTGCCTCAAAA
+
@@@FFFFF:DFAFHGGGHIGHGIHIHDHFDCH>@GHIBD4BEGGCBDHGFHHDDHGGHIHFHFE@DDE:ACECCBC:CCD@CDBA@?B5>CCCDDDCD
@61V
CCTACATGCCTTCCTACCATGCCCACCAGCAGAAGGTGAACTTTGTCCCTCCCCATCCATCCTCCATGCCTGTCACTTCCTCCAGCTTCTTTGGAGCCGC
+
@@CFFFFFHHHGHJIIIJIJIIJJJJJJJIJJIJIJFHIJJEIJIJJIIIJJJJJIIIIJJIIIJIIGGGFHHHHFFFFFDEECEEDDDDDDDDCCDDBD
@61W
AACTCAACCAAGTGAAAATGATAAACTTCAGAAAGAACTCAATGTACTTAAATCAGAACAGAATGATTTAAGGCTACAGATGGAAGCCCAACGCATTTGCC
+
CCCFFFFFDHHBDGGCGJGBHHIIJIIFIJJIBDF@FGEGGIGIGGIEGIJIGGIJJJ>FGIIGAH@GAFGCGG3@DDEBCAAADBDFDDCCBDDDDDDC@
@61X
CTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTAT
+
@BCFDDDDFFFHHIIIBGIEHIJJHIGGIGJGIJJJCGIII;AEGIGCDHGH7ACEHCFFDDDEECEC@BCDDCCDCDCCDCDDDDDBDDDBBDDCABCCD
@61Y
AGAACGAAACCTTTGGGGGCAATTGAATTCAAACCAATCAAGCAAAAATAAACTTTACCAGTAGAAAAGGACGGCTTGAGAAAGGTTGAAGAAGGAGC
+
0(0(((0-8(6=>1=)(-((:()0:8).;)).))-<(.)9).).6>).()).8)3=>998..).)(..((,,'',''&((+(2(+2((++(((((+(+
@61Z
CAGCTCATTCCAACCTTGATGTGTTAAACTATGTGCAAACAGGAGGGAGACTGGAGCCACCAAGAAATTGTCCTGATGATCTGTGGAATTTAATGACCC
+
@@?DDDDDHDDDABGHIGIGGIFHHEGHHHIIIIIIIIIIGGIBEH>)0?DBFHGGD=AHIEHCHHHEEEADDDDBD@ACEEEDCCCC<>ACDCCCC>A
@620
CCGGCCACCGGATGGAGAGGCCAGACAACTGCAGCGAGGAGATGTACCGCCTGATGCTGCAATGCTGGAAGCAGGAGCCGGACAAAAGGCCGGTGTTTGCG
+
?@@BAADADD?C?GG>EGEGI?FFADDEHGEGGEG6FHIDGAGAD?EEA<DCCC:AC>AACCCCCCCCBCCBCCBB??BB-09>BCB98<8<B055<9939
@621
ATCATTTGGAACAGTCTACAAGGGAAAGTGGCATGGTGATGTGGCAGTGAAAATGTTGAATGTGACAGCACCTACACCTCAGCAGTTACAAGCCTTCAAA
+
CC@FFFFFGGHHFHHIJJJJJJIIGGIJCHGIIJJJ?DHCG?DHGGIFGIIJHGCDHC@EHGE@DFHCG>EHGHCEEHFDDEFCCEEEEDDCDDDDDDDD
@622
AAAAAAGAAAAGCACAAAAGGAAAGAGGAAGTGGAAGAGAATAAAAAAAGCAAAGCCAAGGAACCTCCTCCTAAAAAGACGAAGAAAAATAATAGCG
+
<<?BDDA1<3CD;2<+AE3C@E@EAD;DD3D?D?9DDDD389BD<CC@D/=?CCDA@DD@>@A???=;>?>?A>>A>=<(50020>+<<<>>AAA:;
@623
CCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCAC
+
CCCFFFFFHHHHHJJIJJJJJJJJJIJIHHGEIJJGIGGGHIGIJJFIIJIIIIJGJIIIGJJJIFHHHFDFFEEEEDEEDDDDEDDDDDDDDDDDDDDDD
@624
ATCCATACAGCTTTCAGTCAGATGTATATGCATTTGGAATTGTTCTGTATGAATTGATGACTGGACAGTTACCTTATTCAAACATCAACAACAGGGACC
+
CCCFFFFFHHGHHIJJJHIJJHHIHJGIJJIJJJJJGIJIJJIJJJJJJJJJJJJIDIIJJJIJIGIJGIIJJJJGIIIJJJGIGHHHHHDEFFDDDDB
@625
CTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCT
+
CCCFFFFFHHHGHJJIJJJIIJIIJJJJJJJIJIJJJJIIJJJJJJJIIIGIIIJGHIJJIJJJJJJJJHHHGFFFEFEDDDDDDDDDDDDDBDDDDDDDD
@626
GTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTAT
+
<?@DFDDDDDFFHEGGGGIGICHIGG@DF9DECIGGHIE>HEIGGEIIDIGHIIIFFFHFFFF>@;AECCECCBCCCCC:@ABBBCBBBCCCCCCDCCC>C
@627
CACGACCCAGTGTATGAACACAACACCATGGTTGGCAGTGCGGCCAGCCAAAGCTTTCCCCCTCCTCTGATGATTAAACAGGAACCCAGAGATTTTGCAT
+
CCCFFFFFHGFHFGIIJJJJJJJJJJJJJJJDHGIJJJFHIJJFJJJIIHGHHHFFFFFFEDDDDDCCDCEDDEEEDDACCBDDDDDDBB?CCCDDDDEE
@628
CTAAAAACCTTGCTCCTTTACAAGAGAGTCAGGAGTCTTACACAACTGGGACTCCCAAAGCAACATCTTCTCACCAGGGCCTTGGAAGCACTTTGCCT
+
CC@FFFFDHHHFHJJGGIGIIGIIIJIJJIGHGCHDGHGGJGIJJJIJJJGHJJJIJIAGIJJJJIJEHHHGHHFDFFDDD@DCDDDCBCDDDD@A>A
@629
TGAAATACTCAGACAAGAAGAAAAAGAAAAGGGTACACTTGAACAAGAAGTTCAAGAATTACAACTTAAAACAGAATTGTTAGAAAAACAGATGAAGGAA
+
?@?DD;DBFCCF>B<AEBHCGE;3A@=CGGCEADCFHIGEFHCHGGEHIIB@8BA<FHHAHGIIICHCGGICHEHB>CB;BD;@CCCC;?CACCC>:>9>
@62A
GCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATAC
+
8?@DDADDDDDFDCGIE@=FFFEF;EBEB:E1:EF>GB?D?G;DGFG@FGIIIF@CEFEAAAC?;BBC@>;ABABBB@BB:3(5>A<BBB@BA@ABBABDB
@62B
GCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCC
+
?@?=DDDDBBFHDII3A;?EDD?@<2CAEFBCGGFEG@DDDGDGH<=FG>47)5==CDCEC>6?B7@CC:@AA@A>;3>C>A@>?<;>-8<@?>@@CCC8
@62C
CTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGG
+
CCCFFFFFHGHFHIIIIJJJJIGHIJJIIJJJJJJJIJIJIJJJJJJIIHHHGHGFFFFDEDEDDDDDDBDDCDEDDDDDDBDBCDDDDDDDDDBDDDCD
@62D
GGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTC
+
?@@DDDFBHHHHFIAHBBFAEGFCHHHHGBGCBHBDEDHIIICHGIGEBGECGIGFCHIGEHIHC;@A?CE?E>9AAAC@>@CDDCA>>CDCCCCCCC::
@62E
GGGAGACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTT
+
@@@FFDDDHGHHFFHIJEBHGHIBHGFFHDFGICHGIJJJJEDGIHEHD=CCDCDBDDDDDCDDDDDCEDDDDBDDDDDCCBBDDDDB@BBDDCCCBCDDD
@62F
CATCTCCATATCATTGAGACCAAATTTGAGATGATCAAACTTATAGATATTGCACGACAGACTGCACAGGGCATGGATTACTTACACGCCAAGTCAATCAT
+
CCCFFFFFHHHHFGJIJJIJJJJFGJFGIJIFIJIEHIJIJIJGHGIIGGHHIFIJIGIGEEFHIIIIIIGHFFFF>DFCECCEEEDDCDB@B:>CDDCCA
@62G
CTGAAAAGTCACATAATTCTTGGGAAAATTCAGATGATAGCCGTAATAAATTGTCGAAAATACCTTCAACACCCAAATTAATACCAAAAGTTACCAAAACT
+
C@CFFFFFFHFHHJJJJJJGJIJJIJJJJJJJIIJJJGIIJIIHGIJIJJJIJAGIIIJJJJJIJGJJJJJGHFFFFFEEEDEEDDDDDDACDDDDDDDDD
@62H
CCAAAGCTTTCCCCCTCCTCTGATGATTAAACAGGAACCCAGAGATTTTGCATATGACTCAGAAGTGCCTAGCTGCCACTCCATTTATATGAGGCAAGA
+
??84=;?8DD>DD@@?1+3<<229CA9<?*CE<)8)1))?082B)BD@?/88B.8BB<4=CECCA)74@;=A;?7=@@AD@>A>;>;;>B>;;>?(5<9
@62I
TTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTG
+
?@;BB?DDA:?3C2A?FDBC>HBFHIEIE@49C??CDDDGCGFFA6CFFE>DC)@@;=;C>6;@@A@63/',;A(,5:?><,9>ABBBAA>A4434<??94
@62J
AACAGAAACATGGTGAGATTAGTTTTCTAAATGAAGAAGTTAAATCTTTAAAGCAAGAGAAAGAACAAGTTTCATTGAGATGTAGAGAGCTAGAAATCATT
+
=@?DADBD>C?FCFH>BEIIHGA<FEHHHCEAHCDFC@?GHHIIIGCIIEGEGH@HBBDGGHIDDEHH38@DDHCEEG=AAA=;=@D@=;>A;;ACC@CCC
@62K
GAGCTAGAAATCATTATTAACCACAACAGGGCAGAAAATGTACAGTCATGTGATACTCAAGTAAGCTCTTTATTAGATGGAGTTGTGACTATGACAAGC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJIJJJIJJJJJJHIGJIIJJGI@FGGIIJJJJJGHHHIJIJJJJIJIJIHHHHHFFFFDDEEEECEDDDDD
@62L
CACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGC
+
CCCFFFFFHHGHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJIIJIJJJHHHHHHFFFFFDDEEDDDDDDDDDDDDDDDDDDDD
@62M
TGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTC
+
7;?BDDADDF<FBCFG@GEGDF+?FGGCHI;??@D>C9GH>??>FHDCEEEA8CD>G@F;7CEEHBE?C6;?3>>C5?5<@BB?9::::+4>?>@>@:8>A
@62N
GGCCTTGGAAGAGGAGGAAGATGCAGAGGCGCCTCCAAGTTTCAGTGGCGCTCAGTTGGACTCAAGTCCTTCTGGTTCTGTTGAGGATGAAGATGGGGGTG
+
@@@DDDDD?>CD?CFHAC:A<EECC@<FGGAGBDDHGF?0.8=@==CFHAA8::7.;CB76@CCAA3;;CC@;@>5>C@A>@A>@?A>A>CC>:>@<@&))
@62O
GTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGAT
+
CCCFFFFFHGHHFHHIIJJJIJJJJJJJJJJJJJJJJJJJJJIJJDIJJIJIIIJJIIJIJIJJHGHHHFFFFFFEEEEEEEDDDDDDDDDDDCCDDEDDD
@62P
GACCTCATCTCATTTGCCTGGCAGATCTCACAGGGGATGCAGTATCTGGCCGAGATGAAGCTCGTTCATCGGGACTTGGCAGCCAGAAACATCCTGGTAGC
+
CCCFFFFFHHHGHIJJJJJEIJJJIJIJJJIJJJJIIJJJJJHIJJJJJJJGIJIGIIJIJJHGEFFFFFDDDDDDDCDDCDDDDDDDDDDDDDDDD>CDC
@62Q
GTCAAAGTCAAGACAGAAGGGGGGTCAGCTGAGCCCTCTCAAACTCAGAACTTTATCCTTACTCAGACTGCCCTCAATTCGACTGCCCCGGGCACTCCCTG
+
@?@FDFFDHHDBHIIIIIGIBHG@06?CDC@CBCCBDDACCDDDDDDCDDDCDDDCCCEDCCCC@ACDCCCDDDDDCCCDBCD?@CDDDBDBDBDDDDDCC
@62R
AGATGAGAGACCACTCTTTCCCCAAATTCTCGCCTCTATTGAGCTGCTGGCCCGCTCATTGCCAAAAATTCACCGCAGTGCATCAGAACCCTCTTTGAATC
+
@@@DDFFFHGFHHFIEEHEEGFIJJDIIEGIJEEGGGIEH@BFFHGIGIJJJJIIEGHHECHEFEFFFEDCCCC?BDD(:@:@CCDDDDDDBDDDCDDCCD
@62S
CGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCT
+
<@@DD:B;CDF:DFIFBBEFFCC<9F<9A?<CGEECGFE3?DDGIBGFICC8?BC(8.=FECCCE7A=CE?A;BD>B@=;@BB>:>>>?:@ABBABB?<@A
@62T
AGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAAC
+
8=??DD?>>F?F??AC:2CH>GICECG>FA?F9;?D9<:BF???FGDF8DB@:FAAFF>ED7=.@E:EAEF3;@DD33;>;;;;@=;??3<?A:((5<?@<
@62U
CTCTGCGTCTCTTGCTGGGAAGTGGAGCCTTTGGAGAAGTGTATGAAGGAACAGCAGTGGACATCTTAGGAGTTGGAAGTGGAGAAATCAAAGTAGCAGTG
+
@@CFDDDFDFHHHIGIAFG@BFGGIIIFIIIGIHFFFIIBD0BGFGIIIGIGGHG;D@CG;;@EAEG;AC>EB>CCEDC;>;@=ABDDDDCCC(;>CAC@A
@62V
CTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCT
+
CCCFFFFFHHHFHHIJJJJJJJFHGHIIIJJJJJJIJJJJJIJIJJJJIJJJJJIJFIJJJJJJHGHHFFFFFFEEEEEDCCDDDDDDDEDDCC?CDDDDC
@62W
GAGGCCGGCAAAGCCAAGCTTGCCCAGTTTAGACAAAGAAAAGCTCAGGCGGATGGGCAGAGTCCTTCCAAGAAGCAGAAAAAAAAAAGGGAAAAAAGGA
+
?<?DD+@A>@DD>A+9<::?*?):BDD**0*:*09BDDDB@9=())8@).;A?<@@=>=?=5(,:>A:3>>(,39(3<9>A>>?;9&&&(((289<&0(2
@62X
CAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCC
+
?<11A)10@CFDAF@=;FCFC=ADFCCDDG@*?FF@A;F>=FF;;=C>;DEICEEE575?.?B;;@C1;;,;:A?BB@B@AA:4<184::::4>A:>>??
@62Y
CTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGC
+
CCCFFFFFHHHGHJIIJJJJJJJJIJIJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJGHIIIHHGHFFFFFFEEEEEEEDDDDDDDDDDDCDDDDDD
@62Z
GTCAGGGCAGCCAGAGGGCATCCCACCTGCTCCCTGCTGGAACAAAAGGCCCCAGCAAACTTCCATATCCTGTTGCCAAGTCTGGGAAGCGAGCTCTAGCT
+
;<15>?7(@?8.8=1(((((<@)(96(=)9)>)-.)<)).<))9>?<)(.(8;=??<??>>?>;?=?>;==??<<>::><2;==<72;6(06::9<==2::
@630
CTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGGAGCTATGGTCAACAA
+
:?8BD;DD<FAFC:@182ACB?99CGEF39:*:?D?FF@*?*0?009?B8BFIC8.8(8)-665'5996@B;A>;@AB;?BBB?(9?<?@>@::>>@B>8
@631
CACTTCAGCTCTGGCAGTTTTTGGTAGCTCTTCTGGATGACCCTTCAAATTCTCATTTTATTGCCTGGACTGGTCGAGGCATGGAATTTAAACTGATTG
+
CCCFFFFFHHHHHIJJIFHIIJJJGHJJJJJJIIIJCHGIIIHJJJJJIIJJJJJJIJJJJJIIJJJJIIIIJGFHEFFDDDDDDDDDDDEDDDCCDDD
@632
CAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCC
+
@@CDFDDFGFHGHJJJJJJJJJIJJ@HHIJJJJHIGHIJJGIIJJJIJJJJJJIIJJIJIJJJJJIJJHHHGHFFFFEEEEEEDDDDDEEDCCDDDDDDBD
@633
CCCGCCCTCGCCCGAGCCAGCCCTCCTCCCTGGCCATGCTGGACCTTCTGCACGTGGCTCGGGACATTGCCTGTGGCTGTCAGTATTTGGAGGAAAACCAC
+
@@C@DFFFHFFGHIEBHIGGEFIIIIIIIIIFDHGDGGIIIIFDHGHFCHH<CB;?AC@@BDDBBBDDDCDDDCCCB???CCCCDDDE:A3?@8ACCCB8<
@634
GTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGAT
+
@?@FDFFFHDFFCEEGIIIHEGHIIIGIGJJGE@GEIIGGGIGHIGIIJJJGEGHIIGGIIGIEHEFHHFEFDEBCDACECACDDDDDDDDDDDCEEEDDC
@635
CGAATTTGGAAAAGTGGTCAAGGCAACGGCCTTCCATCTGAAAGGCAGAGCAGGGTACACCACGGTGGCCGTGAAGATGCTGAAAGAGAACGCCTCCCCG
+
:;?BD;D>?2CB??C++2ACF@333CE@1E?09:;DE>?<D?99(8/0-.88=6@.7=@@>C9;';;<A@?'3<(5,5(,:>A>::A3>A40;5<3<8>5
@636
GTCGGAGGAAGAGGACAAGTGCAAGCCTATGTCCTATGAGGAGAAGCGGCAGCTCAGCTTGGACATCAACAAGCTCCCCGGCGAGAAGCTGGGCCGCGTGG
+
@@CDFFFFHHHHHJJJJJGHHIIJJJJJJJJIIJIJIJIJIJGIIJIJIJJHHHHHFFFFFDEC>CACDDDDDDDDDDDDDDD>B<BCDDDDDBBDDD09B
@637
CCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCT
+
@?@BDDDDHFDFHGHFHB@HHABFFB>FFGIGFH@GFBEEDBGGIAC9?FB@@FE2;@FGHIGHHG;?E3??>B??AC@C@C@C?A??@C@CAC<<:9<<
@638
CATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATAT
+
@@@DFFDDD;FDCCBAEEGHGDI@EHGDEFGBBBBFBFHID?FGHGIICHHIEGA;CFCC=DHGEGA==AD?;A==BCBCCCCCCD@C:@@>:>@>C:@AC
@639
CTTCCTCCAGCTTCTTTGGAGCCGCATCACAATACTGGACCTCCCCCACGGGGGGAATCTACCCCAACCCCAACGTCCCCCGCCATCCTAACACCCACGTG
+
:=@?DDAAA?A?AFBFEFCGD::?EDEEBC<@9?FEEFFGBEF;??@F:@FFEBB-7?@BABB@BB<B;>BB??BB@@BBB>559<??:@:<A:<>B<>22
@63A
TGCAACTGGACAGATAGCTGGCGTGGATAAAGATGGAAGGCCTCTACAACCCCACGTCAGAGTGTGGGATTCTGTTACTCTATCCACACTGCAGATTATTG
+
?@<+=?AB8AD>FAF<<CFCGA:FGI8C9C9?F>@@D??FHICDBFGGEHIIGHIB=AEHC?7;7;?>(;ACC>>A>;>>::AAA>?C@?C4(3+4:C@CA
@63B
GACTCTTCAAATCAATGAACTTCAAAAAGAAATTGAAATACTCAGACAAGAAGAAAAAGAAAAGGGTACACTTGAACAAGAAGTTCAAGAATTACAACTT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJ@EGIHHHHHHFFFFFEECEEEEDDDDDDDDDDDD
@63C
TGAGGATGCCTCCTCCTTGCCTGAAGCCAGTCCAGAGGCAGGGAGCAGAGTCAATTTCTTTTCTCCTCTGTTGGTGACCTTAGAACCTGTCAACATACT
+
(((8@>)).)))().2)..)<))@<8..)()2)2))((-7((0(7(9)).)/).>>3).86..;))))...98/((.(((7;(-(-(5(,5(((((((,
@63D
GTCCCATCAGTTTGAACAGTTGTCTGGATCCATTTTGTGGATGGCACCAGAAGTCATCAGAATGCAAGATAAAAATCCATACAGCTTTCAGTCAGATGTAT
+
CCCDFFFFHHHHHJGHJJIIIJFHHIIHHIJIJJJIGHHGGIJJJJIJJJJIJIJHIIJIIJJIGIIIJIJJJJIIHHHHGFDFFFFEEDECCEDCDDCDD
@63E
TGATCCGCCGCCTCTCCCCGGCTGAGAGAGCTCAGGGACCCAGGCCGCACCAGGAGAACAACCACCAGGAGTCCTACCCTCTGTCAGTGTCTCCCATGG
+
@?<D?D:DCFD:?E<<<@?:8?:?)8??@6==BBCF>;@;@=?=2-=>?B>;=<5((<>>5<<7?<@B<@<(94>>@?8A??:444>+:::ABAA?>@A
@63F
ACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACC
+
CCCFFFFFHHHHHJJJJIJJJJJJJJJIJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHHHFFFDDDDDDDDDDEDEEFEFDDDDDDDDD
@63G
TCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGC
+
CCCFFFFFHHHHHJJJJJJJJJJJHIJJJJJJJJJJJJJJJJJJJJJJJJJJHHHHHDFFFFFEEEEEEEDDDDDDDACDDDDDDDDDDDDDDDDDDDDDD
@63H
AGAAAAGAAAACTCTTGAGCTAAAGGATAAATTAACAACTGCTGATAAATTACTAGGAGAATTACAAGAACAGATTGTGCAAAAGAACCAAGAAATAAAA
+
CC@FFFFFFGHFHGIBGHIGIJJIFGGGHJJIIJJIIGGIIEHIIJJIJJJGGIIJJIIEHIJJGJGHIIJIIGGEE=CEHFFFFFEDDEDB?CCDDDDD
@63I
ATTAAAACATGAAGCAGAAGTTACAAATTACAAGATAAAACTTGAAATGTTAGAAAAAGAAAAGAATGCTGTGTTAGACAGAATGGCTGAATCACAAGA
+
CCCFFFFFHHHHHJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJIIIJJJJJIJJJJJJJJJJJJJIJJJHHHHHHFFFFFECDEEDDDDDDDD
@63J
CACAAAGAAAGTTAGAACAACTCCGGGCAGAGCTGGATGAGATGTATGGGCAGCAGATAGTGCAAATGAAACAAGAATTAATAAGACAACACATGGCAC
+
CCCFFFFFHGHHHIIJJJJJJIJJJJJJJJJJJJJJIIJIIHIJIIJJJJJJJJJJJJJJEHHHHHGHFFFFFDCEEEDDDEEDDDDDDDDDDDDDDDD
@63K
GATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCC
+
@CCFFFFFGHHHHIJJJIIJJIJIJJJJJJIJJJHGIJJJJJIJIJJJJJJJIIJJIJJJIHEHHHHFFFEFFFEEEDECCDDDDDDDDDDDDDDDDDDDD
@63L
CTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGC
+
;;=ADADDB;DFFGB=FGHHBE@>F@?FAAH9CDGDHIC9B9DGIIGD**=B8B8=FAFHGA;C@E=EEEHC?C@>@>>ACB?@;;@6?C?C:C@@C@:?8
@63M
CACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGG
+
CCCFFFFFHDFFHIIGJJGGIIIHJEIGCHIIJJIJGIGGGIJFHFHIJIGHGHJIEFHFFEFFFFDCACACDCDBDDD<<BACCD>CDCCC@CCCDCDA@
@63N
CTCCTCTGCAAGGACAAGGGTTAGAAAAGCAAGTCCTGGGATTGCAGAAAGGACAACAAACAGGGGGTCGTGGAGTGCTTCCTCAAGGGAAGGAGCCTTT
+
::+A=BDDB:AF=???<A3AA:AFCFEAG;:?BDGDGGBD8BDG?9??D?D>CFI?2@CAA@765B8'98'3819:?::@>>:>>:>:<18?B8?<(9AB
@63O
CCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCAT
+
@CCFFFFFGHFHHGJJJJJJJIIJJJJHGHGGIJJGJGJIIJJEIIJJIJIJIIJGHHHFBFDCDDDDDBDDDCCDDDCDDDDCDCCAABCDDDDDBDDD
@63P
CTTCAAGAAAAATTTGCACAACTTGAAGCAGAGAATAGCATTCTTAAAGATGAAAAGAAAACCCTTGAAGACATGTTGAAAATACATACTCCTGTTAGCC
+
@@CDDDFDHHHDHIGGCECHGGHIIJEHIIDGEGIJIJGEIIGGIEGDHIGCEHIICBDGHIJAFEHEHIHHEHHEAEEFE@D?CE>@;AECDDDCC@@C
@63Q
CTCAGAGTTATGATCAGAATCCTTCCCCTAGAGCAGCTGGGGAGAGGGACGATGTCTGTCTCAGCCCAGGAGTTTGGCTGAGCAGTGAGTTGGATGCTGT
+
???1B2:=CBFDDE<E:2<<EAE@4??@FCAEFBG@?CCF<F1??BDFFEEADE;=@@7;AEAE:;?==@BB@?AB=B@B<B:><>A5>(4:A>ABBA@4
@63R
GGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACAC
+
@@@FDFFEHHHHHEBHIIJIJGIJJJJGEFHIGGHJCHJJJJIJFGHIJIGHIJJGHIJEHGIGGGIIFHGHHDFFFFDDEEDDDCDDDDDCDCCDDDDD
@63S
CCTGGCTTACATGAACCACATCATGGTCTCTGTCTCCCCGCCTGAAGAGCACGCCATGCCCATTGGGAGAATAGCAGATGTGCAGCACATTAAGAGGAG
+
@C@FFFDFHHGHHIJJGGJJIIIJJIHHHIJJIJIIJJJJJJIJJJJIIJGIIIJIJJFHHEHFHFFDECEEDEDDCDCD;ACCCDDDDDDDDDDDBB@
@63T
CAACTATGATGACATCAGAACGGAACTGCCTCCTGAGAAGCTCAAACTGGAGTGGGCATATGGATATCGAGGAAAGGACTGTAGAGCTAATGTTTACCTTC
+
@@@D?>?:4=D8D3C<:CI>38)?C@G9E3C*C9?4)0B9DG?9?FB<*8*(0.-=B)8CFC<).>77?E;58@@@;(.;=(5-5>>,5@A>BB>ABB(>9
@63U
CTCTTTCATCTGCTGCTAAAAGTGGTACAGAAAAAAAGAAAGAAAAACCACAAGGACAGAGAGAAAAAAAAGAGGAATCTCATTCTAATGATCAAAGTCC
+
@@CFFFDFFDFFHIIGIGEIHC:AE3ACHHCCGBA@?DHIGEDHGGGGIEACCFE;@@E?C;A?@ECA>?=@?CBDDCC>ACDD:>ACDDA:>@CC@::>
@63V
ATTGAATACTGCACCCAGGACCCGGATGTAATCAACACCGCTTTGCCGATAGAATATGGTCCACTTGTGGAAGAGGAAGAGAAAGTGCCTGTGAGGCCCA
+
C@@FFFFFHGHHGJJJGIJJJJJJIGGJHIIJIJJJJJIJJIJJIJJJIIHHFFFFFFF@CECEEEDCCD>ACBBDBDDDDCDDDCCDDDD@CDDDDDDD
@63W
AAGCTTTCCCCCTCCTCTGATGATTAAACAGGAACCCAGAGATTTTGCATATGACTCAGAAGTGCCTAGCTGCCACTCCATTTATATGAGGCAAGAAGGCT
+
CCCFFFFFHHHHHIJJJJJIGIJIJIIJJJJJJJJJJJIJJJJJJJJJJJJJJJJIIJJJJJ@FHIJGIJIHFHHHDFFFFFEEEEEEEDDDDDDDDDDDC
@63X
CAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCC
+
@CCFFFFFHGDDFGIGCHGFEEB8CDBHGE@DGHHEGIIGIIJCF@EGGGGHC?=?EEB@DF>>A;@ACCCDDDDD(:@C@CA<ABBBDCCAABACCDCDB
@63Y
CAGGAACCCAGAGATTTTGCATATGACTCAGAAGTGCCTAGCTGCCACTCCATTTATATGAGGCAAGAAGGCTTCCTGGCTCATCCCAGCAGAACAGAAGG
+
@<==DDDDFHD=?EFHGIEE>FCHEHB<EFEACHEGCGGIHIG@BGCBHIG<D>?DHCHG<CEE=G?CA@GGCC;?=@C;;@A@CCA>@9==5><?A:A?B
@63Z
GTTCGCAAGTGCAAGCCCCAGATGAATTACGACAAGCTGAGCCGGGCCCTGCGCTATTACTATAACAAGCGCATTCTGCACAAGACCAAGGGGAAACGGTT
+
CCCFFFFFFFFDBHIGIIGIHGIIIIIIIEGIJJJIJJJGGIJFEEGIHGEFEDDDDCDDDDDDDDDDAABBBDDCDDCCCCDBDDCDDDDDDDDBCBD8<
@640
CGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCG
+
@?@BDDFDFHH?B@FBGHDE<DGGHCG>G@GFHCEBB@CHAAECGE<5,9?;@@CEEEECCC5@CCCAB@(5>559<&5<AA<@B8A?CC(4>C(4@>@A@
@641
GTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCC
+
@@@FFFFEFHHHHIBC;FE>FHGGAGIII9FEIFHIDDGHIGGIIGIIIIIIIFGGGHIFFFHEGFC>;?A@CCCCBBC?CCCCECDCCCCCA??CC@CBB
@642
CCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTTATGGGCAGGAGT
+
@@@DDDDDAFHHFBHIJGIGEIJJJIIGIIIJJDGEGDG>GHIIAG;FG>FHGHIGIIIGGEHBBFB==ADDBBD@@CCC>ABB,50??CCC>??<>BB<3
@643
CCTCAGTGAAAAAATCAGTCTCAAGTAAAGGCCAACCAAGCCCTCGAGCAGTTATTCCCATGTCCTGTATAACCAATGGAAGTGGTGCAAACAGAAAACC
+
@C?DDDEDFHGFDIIIGGHHIIJGGHHHA@FFBHHIJGIII6DEGGAFEFHGHIIIDHIIC?EECHFBCFDBCBEDEEDDCC@CC;<CADDB@<CDDDCD
@644
CTCTGATGGACAGCAGATACTTGTGCCCAGCAATCAGGTGGTCGTACAAACTGCATCAGGAGATATGCAAACATATCAGATCCGAACTACACCTTCAGCT
+
BCCFFFFFHHHHHJJJJJJJJJIJJJJJJJJJJJJJJJGHIFHGGIJJJJJJJIIJJJJIIIJEIJJHHHHHFFFDFFFEEEDDDDDDDDCDDDDDDDDD
@645
ACTTAATGAAGCACATAAGTCCCTTAGTACAGTGGAAGATTTGAAAGCTGAGATTGTTTCTGCATCTGAATCCAGAAAGGAACTAGAATTAAAACATGA
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJIJIJJHHJJJIIJJJJJJJJJIJJJJJJJJJJJJJJJJJJJIJJJJJJJJJIJHHHHFFFFFFFEEEEDDDD
@646
CCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAAC
+
@@@DDDDDFFHGFGCFHBHFHIIIIDEGGIGEICHIEHIIC<B?FHIIIIHIIIIGIIIICHIGBEAE@@@D>;ADEECCCCCC@CCCCCCCCCCCBCCC
@647
GCAACCTCCCACTAGTTACCCACCCCAAACTGGACCCTACAGCCAAGCTCCAAGTCAATTGAGCCAACCGAGCAGCAGCTACGGGCAGCAGAGTTCATTCC
+
11=++222?A>B3==,?=?++++<1:=))?*1?A)0))=AB*0/=)(<A<A788A)/)=).=)7.=);',''''(((,,:>9',0-;-9<8((43::?3++
@648
TGGCAGTGCGGCCAGCCAAAGCTTTCCCCCTCCTCTGATGATTAAACAGGAACCCAGAGATTTTGCATATGACTCAGAAGTGCCTAGCTGCCACTCCATTT
+
@C@FFDEEHDFHFGHGEHGIHEHIFGJJJIFGIGIIHEHHEHIGIGGGGIEIGIIFFDECDDFFFCEEEEEEDCDCCDDDCCDC@CDDCCCBCDDDDAADD
@649
GGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAAT
+
CCCFFFFFHDHHFHIIHIIJHHHHIIIJEIJGEGIJIIJJJIIGDHIJJJIJJIJJGIIJJJJJJHHHFFFFFE@CCEDDCDDDDBCDDCDDDDDCCEDE
@64A
GACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTG
+
CCCFFFFFHHHHHJJJJJJJJIJJJGJGJJJJJJJJJJJGIJJJJJJJJJJJJJIJJJJJJFFFDDDEDDDDDDDDDDDDCDDDDDDD9@CDDDCDCDD@C
@64B
CTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACC
+
;??A;BDDFB?FHGDFHIIGGIIGGGIIIIGAFF?DFDGHG>>FFF@HAFEGIEHGHHH8?;?C?>CCCB(5@CCCCCC;>CC5>BBBCCC>ACCCDCCCC
@64C
TTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGC
+
@@@DADDD??FFFIGIIIBHEGDAHGGIIICHIIIEIGIGHGHIII<FEGBAFHHEEH@EIIH==E?EDEECEEC>CCCCCBBCCCCBCCCCCBBCBBBBB
@64D
CAGGAAAACACGACATGTGAATATCCTACTCTTCATGGGCTATTCCACAAAGCCACAACTGGCTATTGTTACCCAGTGGTGTGAGGGCTCCAGCTTGTATC
+
@@@D=DBDH?C<A?<EEGB4FH9FH<EHBFHBG<??<BEDGGHGDGEGGCD38=>@8=@:@A9@D@A;CE>HD<C?7>@(;A=3>;?B@BB@A3>@CBCD4
@64E
CTGGATATGCAGGTTGCAGCATTGCAGGAAGAGAAAAGTAGTTTGTTGGCAGAGAATCAGGTATTAATGGAAAGACTCAATCAATCTGATTCTATAGA
+
CCCFFFFFHHHHHHIJJJJJJJJJJJIJHIJJJIJJIJDHIIJJJJJJJJIJIJGIJJIJJ=FHIJIJJJJJJHHHHFFFFFFEEEEEEEDEDEEEED
@64F
CGACTGATGACTCTGAGGAGGAGCGAGCCCAGCGGCTGGCTGAGCTCCAGGAGCAGCTCAAAGCCGTGCACGAGCAGCTTGCAGCCCTCTCTCAGCCCC
+
C@@FFFFFFDHHHEHJIIIIJIIIIJGGIJJIJIIJGGIEGIEEHHHHFFFBCCDCDCDDDC@A?B=@BBC?BD<BCBDCDBDDCDDCA9CCDDDCDDD
@64G
CGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTT
+
CCCFFFFFHGHGHJJJJJJJJJIIIIJJJJJJJIJJFHJJJJJJJJIJJJIJJIJJJJJHEFHFFFFFEEDEEDDCDCCDDDDDD;@DDDDCDDDD>CCCD
@64H
TGCAGGAAAAGAAACTCTTTCATCTGCTGCTAAAAGTGGTACAGAAAAAAAGAAAGAAAAACCACAAGGACAGAGAGAAAAAAAAGAGGAATCTCATTCT
+
@@CFFFBEHHHFFJJIIIIIIIIIGHGIGIGHHHJJHIIIGGIJEGGIIJIHHIIJGHIJJGHFEEEFD@AEBCDCDDDDDDDDDDBDDAACCCCCDDED
@64I
CAGCAATCAGGTGGTCGTACAAACTGCAACAGGAGATATGCAAACATATCAGATCCGAACTACACCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATG
+
?1::BBDDBDD<CDDF<GIFFI>3C?3**1111??3?B*00?*00??D@FDEEF)8=5C@D=3?AAA3;;;7@@>AA(;ACBBA;AB9??AAA:<@?@>@
@64J
CTAGAAATCATTATTAACCACAACAGGGCAGAAAATGTACAGTCATGTGATACTCAAGTAAGCTCTTTATTAGATGGAGTTGTGACTATGACAAGCAGGGG
+
CCCFFFFFHHHHHJJJJJJJJJJIJJJJJJJJJJJJJIGJJIIIJJJIIJIJJIIJJJGHJIJJJJJIJJJJJIIJJHHHHGCDFFFFEEEEEDDDDDDDD
@64K
CAGGAAAGCCTACAAATTTATTAAGGGAAGAAGAATTTGGTGTTGATGATTCTTATTCTGAACAAGGAGCACAAGACAGTCCGACTCATCTAGAGATGATG
+
@@@DDDBDFFDFFFEFB4ABD9CBHFFADFEFGDCEFEFF8B?;DB4??4B?D<DA>B@BBF@BCFE@DAEA?AAC>?B;??=?888@B>>5:5>::A:>A
@64L
TTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAAC
+
@@CBDDDFHDBFHIGGHFGBGHIGIIEFHGE>?DHIBDFHGHIIGGGGHCGIIGFCEHCG<DHGIHEBBACCEDACAAACA?BCDD?:A>ACDAC@CCDCD
@64M
TGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGC
+
CCCFFFFFHHHGHJJIJJJIJJIGIJJIIIHIJIEHIJJJGHIIIJIIIJJJJGJIGIJIJJIIJHHHHHGFEFDCFCEECD>CBCDDDCDDDDBDDBBB
@64N
CCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGG
+
C@@FFADDHBHFHIGCBHJJGGIGHIGIEHEDBBAFHIJJIIGHJAHCFHGJICEG=CEEAEDEFCDACECC@@CADBDD09AACCCDBADDDDDD@CDCC
@64O
CCGAAGGATAGGAGAAAGAGAAAAAGGAAGCCGAGGAAGAGGATGAGGACCTCCCCAACTTTGCTTACCCCTCGGCCGCTAAACTTAACCTCTCACCCAGG
+
-((2--(.)2.))):6));.@?).@?@9)2(((:(<=<1(.6())))))((..(69=?((:(.=((((:(((',38;&&&&0(8;(8+8;5;(((++((+(
@64P
GACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCC
+
CC@FFFFFHGHHHJJJJJHIIIJJJJIIJJ@DGGIJJJJIIJJJJJJJJJJIHHHHHHFFFFFAEEEEEEDDDDDEDDDDDDD@ACDDDDDBDDDDDCDD
@64Q
CGAGCAGCTTGCAGCCCTCTCTCAGCCCCAGCAGAACAAACCAAAGAAAAAGGAGAAAGACAAGAAGGAAAAGAAAAAAGAAAAGCACAAAAGGAAAGAGG
+
CCCFDFFFHHHFHGJJJJJJHIIIJJIIIGIGIJHIIJIIIHGIIGFIIIIIIGHIJJHGFHHFFFFFACCCCBDDDBDDDDDDDDDCDDDDDBBDDDDDD
@64R
AGCTTTCAGTCAGATGTATATGCATTTGGAATTGTTCTGTATGAATTGATGACTGGACAGTTACCTTATTCAAACATCAACAACAGGGACCAGATAATTTT
+
@@BFFFFFFHGHHJJJIIIJJJGJJJJJIJJGHJHIHIGFFHIHIFIJIJGIIIJIGGIJGIIJIIGGIJIIIJIJJJJJJJJEEHHF=DFCDDCCDDEED
@64S
GGCATTCAGAAAAACAGGCCAGCTATGAACTATGATAAACTTAGCCGTTCACTCCGCTATTACTATGAGAAAGGAATTATGCAAAAGGTGGCTGGAGAG
+
@C<ADFFFHHHHHIJJJJJIJHIJJIJIJJJJJJJJIJJJJJJGGIJJJJJJJJJJJJJIIIGIGGHHHHHHFFFFFEEEEEEEDDDD;@BDDDDBDDD
@64T
CTACTTTTCATAGAATTCAGGACCAACTTCAGTTATTCAGAAATTTTTTCTTAAATAGCATTTATAAGTCCAGAGATGAAGCAAACAACAGTGGAGTCAT
+
CCCFFFFFHHHHGJJIJJJJIIJJIIIIIJJJIIJJJJJIIJJJIJJJJJJJJJJIJJJJJJJGIIIIIGIJJJJIIHHHFFFFFEFDDDEDDDDDCCDE
@64U
CCAGCTTGTATCACCATCTCCATATCATTGAGACCAAATTTGAGATGATCAAACTTATAGATATTGCACGACAGACTGCACAGGGCATGGATTACTTACAC
+
CCCFFFFFHHHHHJJJJJIJJJJJJJJJJJJJJJJJJIIIJJIJIJJICHIJJJJJJJJJJJJJJJIIJJIJJHHHHFFFFFFDDDDDDDDDDDCCDEDDD
@64V
CAACAAATGAAGTTGTTTTGGCTGTGGAGTTTCACCCAACAGATGCAAATACCATAATTACATGCGGTAAATCTCATATTTTCTTCTGGACCTGGAGCGGC
+
@;?DD8DB?DAADGF4AFA?@9EF3<9+8?EGF9<11??BFE?F49<?B?8**8=8B=FE:CFEGFE=';=;B>BBB3>BDD3>A((-;>?(9(,529;<>
@64W
ACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCT
+
CCCFFFFFHHHHHJJJJJIJGJJJJJJJJGIJJJJJJJJIJJJJJJJJJJIJJJJJJJJJIJJIIIIIHHHGFFDDDDDDDDDDDDDDDDDDDDDACDDD
@64X
AAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGC
+
;?@D?DDDF?FF?3A?FEHFFFDFFEEFG>FB**1?11?D<<?90??8)(/9B3(=C)B38@@277)7>E?AA?@(93'',(>3;@:>5,:>A3>AAAB<8
@64Y
GTACAGTCATGTGATACTCAAGTAAGCTCTTTATTAGATGGAGTTGTGACTATGACAAGCAGGGGTGCTGAAGGATCAGTTTCTAAAGTAAATAAAAGTTT
+
@@@DFFBBBFH?FB?FDFHGIIE?HHAHI<FHFHIEFCGGHC>GGCHCHGIIHHCHIEB=DEHHI5;CEGHHGHGFFFFBEEDCDEC@5>>@;ACCCC>@;
@64Z
CCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCT
+
@C@FFFFFFGHHHJIJIJJIJJJJGIJJIIIIGGIJGIJJJJJJIJJIIJJJIJJJIJJJJJIGHIHHCHHFFFFFFEEEDEDDDDDDDDBDDBDDDDDC
@650
AACCACACAAAAAAAGTCACTTTTTAATTTTATTTATTATTTCTCCTCTTAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGC
+
=?@D;A?DFH?;<@GHEGG<BC?DHBGHEGGCDHEI@???BFHHGI<BG@GB=G@;@EE8B>>?@CCCC?;=?ABB?A>5@A@C>>ACC>??AACCCCA@C
@651
CCAGCCAAAGCTTTCCCCCTCCTCTGATGATTAAACAGGAACCCAGAGATTTTGCATATGACTCAGAAGTGCCTAGCTGCCACTCCATTTATATGAGGCA
+
CCCFFFFFHHHHHJJJJJJJJJJJJJHIIIIJJJJJJJJIJIJJJJJJJJIJJIJJJJJJJJGJIJJJHHHHHHHFFFFFEEEEEDDDFEEEEFEEDDDD
@652
AGCAGCTTGGAGTTTGTCTGCTGAATTAACCCCAATACATTATCCTGGAACTGATGGAGGGAGGAAACCTTCTAACTTATTTGCATAAAGCCCGGATGGC
+
::+<A@A;+@=@?;<@<=3+<AB<C=+<2+<5)@??:1*?AB44?*0=20***=/*=7=('5;4=(77=))))).(5;;356((;(;;;-599',5&5+(
@653
ACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGC
+
CCCFFF?DHHFHHJFIJJJIGIJJIJIJIGIDGGBFHIHIJJGFHIIIHIIJJICGGIIJJJIIIIIJJHHGGHFEFFD@CEC>BBADDBBBCABDDDDDD
@654
CTCACCTCTCAGACAACTAAGACAGATGACCCCCAATTGAAAAGAGAAATAAGGTTAATGAAAAACAGAGAAGCTGCTCGAGAATGTCGCAGAAAGAAGA
+
@@CFFFFFHGFHFIIEGGIHIIGGGIJJJIIJIJIIHIJGIJJGGIIFGGIGIICHIJGGGGIHIGJHEEFFFFFFFCCCDBDDDD:5<B:@@ACCCBDC
@655
AAACTATTGCAGCTTGCCAGGACCTTTGAGGGCCAACAGCCCACCCTTGAGGTCCAAAGAAAATCAAGAACAGAGCTGTGAAACCGTAGGGCATCCCAGTG
+
<@;?DDDDFHB<CGBF@ECF=FHIIFFAEDBFG;?FD60?B=8DFHGBDFGH8@=CHHG>D;?EEEHDEEECA>CCC>>AADACBB@<?B?92399?A@>>
@656
CCCACACCTGGGAAAGGACCTAAAGGTGTATATCAAATCAGCAAACAAATCAAAGCTCATGATGGCAGTGTGTTCACACTTTGTCAGATGAGAAATGGGAT
+
@@@FFFDDHFFHHBDBHIEGGIGGHG9C:CGGJJJJIJJJIJIIEGIGHEGIIGGJGGIGIHCHHGEH7A7?AA>@DDFFEDCAEDCCCDCD@CDDDCBCD
@657
AGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACC
+
CCCFFFFFHHHHHJIJJIJJJIIJIIHHJJIIJGIJJJIEHIJJIJIIIIGIHHHFFFFFE@CEEECDDDDDDDDDDDDDDDDDDDDCDDCCDDDDDCDBD
@658
GTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGC
+
??;=BDB?+2A2CEBDE?;;9+3)1::CD?:D;;DDD*0*??BD4BCA<D;A6?C@9;A;AAA3@AA3;;;>A5:9?????<<<<<AA34:8<<8<<>1+9
@659
GCTTGCCTTCTCAAAGTAAAAGATGATTTAGAAGACAGTAAAAATAAACAGGAATTAGAGTATAAAAGTAAACTTAAAGCACTTAATGAAGAGCTTCATTT
+
0(((2168=6..=)<>@==18.(9@)<:<1=)84=<7):);):1;).<<<7>1=><?8><7=>>?@8:/=>;8>=8>>==>?;;>88==<?;=9=5:7:1;
@65A
ACCACCCCTCAACCCCTGTTTTCCCCTGCCTTCCTTGCAGAGGCCATGGAGGACGAGGAGAGACAGAAGAAGCTGGAGGCCGGCAAAGCCAAGCTTGCCC
+
CCCDFFDFHHHHHJJIJJJJIJJJJIIJIIIHJIIJJJJJDIIGIIJIJIJJJIJBEHDFBCDCEDCDDDDDDDDDDDDDDDDDDDB?CBDDBDCDDDCD
@65B
GCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTC
+
@@@FFFFFHHFGFHIGIJCGGHIGIJJJIIJIIIIJIIGGEHIJJJJJIIIJJJIJEHHHF?AEACDCCCDD;?CDD@ACDCDDDCCD?BDDDDCDCDDD
@65C
GAGGACGGGCTGCATAGGGAAGGGAAGCCCATCAACCTCTCTCATCGGGAAGACCTGGCTTACATGAACCACATCATGGTCTCTGTCTCCCCGCCTGA
+
<@@FFFFFHHGHGIJJIJJJJJJIIJJJJJIJIIJJJJJJJJJGIIJIIJHDEFFDFFDEDEEDEDDDDDBDDDDDDDDDDCCCCCDDDDDDBDDDDD
@65D
CAAGAAAACAGGGAATTTTTGGGAAATATGAAAAGCCAAAATTTGTGCAGTGTTTAGCATTCTTGGGGAATGGAGATGTTCTTACTGGAGACTCAGGTGG
+
8??7DADDFFAF?G;EGFEEFFFFCGI@FGIIIIF3BFFFCBFEC4BFAD9CB<8BD)>4=@CF@EIA(5=B;;BD>@;>ADCA@BB@?@:<:@>:AA@?
@65E
GCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCAC
+
CCCFFFFFHHHHHIJJJJJJJIJIJJJJJJIJJHIIIIFEHIIJ@FGIJIJJIJHHHHHFFFFEECEEEDEDDDDDDDDD
@65F
GCGGCAATTCACTAACAATAAAACAGGGAATTTTTGGGAAATATGAAAAGCCAAAATTTGTGCAGTGTTTAGCATTCTTGGGGAATGGAGATGTTCTTACT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJHIJJJJJJJJIJJJJJJJJJJJGIJJHEHHHHFFFFFFCEEEEDDDDDDDDDDDDDDEEDDDD
@65G
TATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGC
+
CCCFFFFFHHFDFHIJJJJIIJIJJJJJJJJJJJJJJJJJJJJJJJJIJJJHIJIIIIJJIJIIIIIHHHHHFFFFFFFFDEEDECDDDDDDDDDDDDDDD
@65H
GTTTATTTCATTGCATCAGTAGTAGTACTATTTAATTATGAGGAGAGAACTCAGCGACACTACCTGGGCCATACAGACTGTGTGAAATGCCTTGCTATAC
+
?:?DDDDBDBFBDHGFH?CCFH:CB<CDHBFH@EBBHEFF?GFCGBHEGGIIIGCFGGIGEGHIGIIIIHFFEC@C;BDCAC6;ADCCCCCCCCCCCADC
@65I
AGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACC
+
?18B?3:A+2<C?C=EEA@FE>EED4CB@><<DDDCBD81*9?;*0'@;@/A?64;;@@@@>A>AABAAAA?:6;;?????>??AAAA<::>3:::A?A<8
@65J
GTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCC
+
@@@DFFFFDADFHBGFHEGGGEDAGGGIIIDGFHGIIIII?BDADFHHHIIII@;@GCCDH9CECH:AABFDD8?=AAB>CCDCDC>C6<><B88ADDBBD
@65K
GAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCAC
+
CC@FDDFFHACBDFGGAGGCGIGIICHGDGHCHHIIGIIIIFDGGGHIGE>GGFHHHFFCEEECCCCDCCCCCCBBBBBBCCCCCB?CCCCBCCCCCEC
@65L
ATTAACTGGAGGAGGGAAAGACAGAAAAATAATTCTGTGGGATCATGATCTGAATCCTGAAAGAGAAATAGAGGTTCCTGATCAGTATGGCACAATCAG
+
CCCFFFFFHHHHFHGIGIJJJJJJJJJJJIIJJJJJIDHJJGJJJFIIJJJJJIIJJJJJJJJIIIHHHHHFFFDFEEECDEEEDDEEEDDDDDDDDDD
@65M
CCAGAAGTCATCAGAATGCAAGATAAAAATCCATACAGCTTTCAGTCAGATGTATATGCATTTGGAATTGTTCTGTATGAATTGATGACTGGACAGTTACC
+
@@<DDDDB><CFFFBEFB4BFB3CH<HB@E2C<E*?9E>*?:*1?DBF@*0??D@DG@FBDDDF@:BFF=FF788=CCAEFAEFIFF=>AEDBB:;;>@@A
@65N
CGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTC
+
@@CFFFFFHGHFHIGHGJIJGJGIJJJGGGECHGIJJJDHJEIJIJEEHIJJHGEICHIGGGGHHHADDDE@ADCCBBBCCACCDECDCDCDCDDCDDB?B
@65O
ATCAACGAGGAGGACACAGTGCCTCTTTCTCACTTTGATGAGAGCATGGCCTACATGCCGGAAGGGGGCTGCTGCAACCCCCACCCCTACAACGAAGGCT
+
C@@FFFFFHDFHFGHGIGIGHHHIIIJGIJJGGGIHIEGHGIHIGIDFGAGHGIIGIIGHGEFFFFDDBDDBCDCDDDBBBD><BDDB??@CCB??@BBD
@65P
GAAAATGTTGAATGTGACAGCACCTACACCTCAGCAGTTACAAGCCTTCAAAAATGAAGTAGGAGTACTCAGGAAAACACGACATGTGAATATCCTACTCT
+
@C@DDFFDFFDHHIFGGHJIDGHIGIGGGGIGIHGGGGGIIEHGAHEHGHGIGIGGGIJIIIGII@AGHDHIIJFHGBCDBE<ABC@CAD>ADFEEDDDCD
@65Q
GGATAAATTAACAACTGCTGATAAATTACTAGGAGAATTACAAGAACAGATTGTGCAAAAGAACCAAGAAATAAAAAACATGAAATTAGAGCTGACTAATT
+
???:BDDDHADBDADE?CFDIE@DBHF@CADEG@FHIEHBHC<C;?;BFBBFD9?BFGAFE1BGA@GHC@D@@EHEC>B?CCCE;>C>5;55,5@3:ACCC
@65R
CTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTAT
+
@@@FDFFFFHHGGFIIBHGIJIGIGIGIGHHCHGGEHIGEGGJGIBBFD>CBGHIICCGIFHGGIIJCEACEE@@BE@6=CECCD@B=BBDB@<BBDBCCC
@65S
ATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCT
+
CCCFFFFFGHHGHJJJJJJJJJJJJJJJJJJJJJJJJJIJJJIIJJIJIIJIJJIJIIGIIIJJJJJHHHHFFFFFFEEEEEDDDDDDDDDDDDEDDDDDD
@65T
GAAGGTTATAAACCAGGTATCTCTACATCAGGATGGCCATCTAGGAGGCGCTGGGCCTCCTGGGCACTGCCTGGTGGCTGATAGGACTTCAGAGGCTCTGC
+
@CCFFDEFHHHHHJJJJGIJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJIIJJJJHHHHFFFFDEEEEDDD@ABDDDDDDDDDDDDDDDDDDDDDDDD
@65U
CCTACACCTCAGCAGTTACAAGCCTTCAAAAATGAAGTAGGAGTACTCAGGAAAACACGACATGTGAATATCCTACTCTTCATGGGCTATTCCACAAAGCC
+
CCCFFFFFHHHHHJJIIJJJJJJJJJJJJIJJJJJJJGIJJJJGIJIJJJIJJJJJJJJJJJJJIJHHHHHHHFFFFFFEDEEEEDDDDDDEEEDDDDDDD
@65V
GGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGCCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGGCAAT
+
?@@D1B3?=+A<,A@F@EE:AAF<:<CEF3*:):C4?B):3BBCB?DD;B;8;FB@8=C=7@:@E8';56;BDD>A6@@B:;A>?B(58(:5@>A(+(83
@65W
AAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGT
+
CC@FDFBDFHHHGJGEGHJGGFIJJGGIFGGIJJJIJGIJJ@GIIDEHGIJJJJIJJEBAHGHHHFDBDDFDFEEEDDBDBDBBDDDDDBDCCCCC>CDD(
@65X
CTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTT
+
@@@;?:DBFHHHDCGGECFFHBFGCEHIIIIIIIDFEEEGEHEHDCGIG@HIIGIIEGGAAEHCEH@EHEA@BFDCEEEEEECCAC;;=C@A?@=BB@CAD
@65Y
ATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCC
+
@8=DDDDDBHBCCFHHBBA@?GGH9+<A<EB>BF>FGDBCD=;?8BB?@A?B;B<BG@FHE@FGE;C8(66?/,3;@A>@@>AC@CC;ACCC<>28839AB
@65Z
TGGTCGTACAAACTGCATCAGGAGATATGCAAACATATCAGATCCGAACTACACCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATGACATCTCCTGTG
+
@@@ADDDDHFFFHGB<CEFHDGCE8??GE@<?F???FBDB<FHGF?BBF;FHG@B@F@@FGIB>@G7?AEH@ADDFDB6>;;AC5=3>CCAC>ACCCCCCC
@660
GAGCAGCTTGCAGCCCTCTCTCAGCCCCAGCAGAACAAACCAAAGAAAAAGGAGAAAGACAAGAAGGAAAAGAAAAAAGAAAAGCACAAAAGGAAAGAGG
+
CCCFFFFFHHHHGIJIJJEGGGHHGGEHIGEGG>D@?DHJJGGHIIGEIJJIHIEHIEHEHEHHFDDDEEEEDDDCDDDDDDDDDDCDDDDDDDDDDCDD
@661
CAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTTATGGGCAGG
+
CC@FFFFFGHHHHIIEHIJEHIFGGJGGIJJGGEGIJJIGGIJJIIIIIHIIGD@FAHIJJJIGHFFDECDDDDDDB?CCCA@DCDD9<@DD@CDCDB?@D
@662
CAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACT
+
@C@DDAFFFHHFFGDHGHHIIJIIIEIIGGBIIIEIGEIIIDHIJICHH<FHIJIJGIJIIJIIIGHHFHHGEFF>DECABD=?BCCBDDDCCD?ABDDDB
@663
CCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTAT
+
;93?(>4=>?1(-))24)<2=@/;><(1<(;7<>>1<>???<?.-<'9/(:=?>(..6=80(6==177(5;5;5;6/,58-6565;::7<<8+268;9(++
@664
ATCAGAAGCCACAAGTGGGAATGAGGCCCTCCAACCCCCCCACACCATCCAGCACGCCAGTGTCCCCACTGCATCATGCATCTCCAAACTCAACTCATAC
+
C@CFFEFFGHGHHJJGIIIIJIJJJJJJFIJJJJJJJJJJJJIJHGHHFFFFFEE3;@BBACAACCDDDDDDDDDDDCCDDDCDDCCDDCDDDCCCCDDD
@665
GCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGAAACTACAGTTATCCCCAGGTACCTGGG
+
@@@DDDDD3:?DHI@EHEHHIEHGGIIGG>HHD?E;;C:??.BCFGGD@CCG?CA=CBDBEE@CA>33>=CA(;?55@3@CE@CDCCCBCBB>CCCAC@B
@666
CCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGT
+
??@DDEFFBHHHHGHIJIGGGHGGIGJJJGCBBBDFHGGBGGIGAGHAHGIIGGHHAA@DFFFECEECEDCDBCDCCDCA?<<@DDDDD???CCAA:A?BC
@667
GTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACA
+
?8?;DDBAFFDAFB:AEG<CF?<F<B::EGGIBFB?FF?BG>?B@F@BDFIFF;=;;@C7=C=EEFFF??A;?B8BC@@?@B?B2;@9@>A:A@??B?@
@668
GGAAACATGGCTTGCAGAAGCTCAGGTACCTGACAATGATGAGCAGTTTGTACCAGACTATCAGGCTGAAAGTTTGGCTTTTCATGGCCTGCCACTGAAA
+
CCCFFFFFHHHHHJJJJJJHIHIJJJHHJJJJJJJJJJJJJIJJJJJJJJGIIJJJJIJJJJJJJJJJIIJJHHHGHHFFFFFEEEEEEDDBDDDDDDDD
@669
GATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGC
+
@@@FFFFFHHHHGGGFEGHGIJJIJJJJFIGBEHEHIJGIHIJIGHGGEGGGGIGHHHFFFFDDDEDDCDDDDDDCDDDDDDDDDDDDDDDDDDDDDDDD
@66A
CCAAACTGGATCCTACAGCCATGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGAGCAGCAGACTGCATCAAGAGATAGGCAAACATATCAGATC
+
:=122<?+<@A7A+2?=A3<=+?+<A=@AB@@<1*:?A=?BBB))009**0/==>AA7'''--..=(..=7.)).;(6;((5;5;??295,,:=:(9>((
@66B
GGTGATTCCACACTGGGGTCTTCCAAAGAAACCCTTCCACCCACATGCCAAGGCAATCTCCTTATCATGGGGACTGAGGATGCCTCCTCCTTGCCTGAAGC
+
@@1BDFDFFFHHHGJJJIIIJIJGGIIJFGJJIIIEHGIHHEHGIJIGGGIGJJIJJJIJGJHIHFEHFHFFFDEDEEDDCDDD>CBDDDDDDDDDDDCCD
@66C
AGCGCTTTCGTGCTTCCTCATCCCAGTTCTCCGATCCCTGGCCCGGCGGAAGCCCACCATGACCCTGGAGGAGGGACTGTGGCGGGCCATGCGGGGATGGC
+
@@@DDDFFHHHHHJJJIIIJIIJJJIHIJJJJJIIJJJJJJJJJIJIJDDDBDDDDDDDDDDACDDDDADD@DBDDDDBCDDDBDB@BB?C?<BD&55?@<
@66D
GAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGAT
+
@<?DDDD?CFCHDHDFBHG@<GGG@GHA<A?BG9BGCBFEE>DDBFG>2@G@F>=;BEEEBB2;;=??ACA5ACCCC@CCC<><<B<A<B<@BCACC@B:
@66E
CACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGT
+
CCCFFFFFHHHHGIJJGJIIGIIIJJJJJJJJJJIJIGIIIJIJIIJJJJJJJIJJJIJHGFHHFFD?BDDDDCDDDDDDBDDDDDDDDDDDDDDDDDDD:
@66F
TTATAGATATTGCACGACAGACTGCACAGGGCATGGATTACTTACACGCCAAGTCAATCATCCACAGAGACCTCAAGAGTAATAATATATTTCTTCATGA
+
CCCFFFFFHHHHHJJJJJJJJJJJIJJJJJJJJJJJHIJJJJJJIJJJJIJJJIJJJJJJJJHHHHHFFFFDEDEEEDDCDDEFDEEEEEFEDEDDEEDD
@66G
CCAGCTTGTGGAACCCAACGTACGGCTCCTGGCTTACAGAGAAACCCACCAAAAAGAATAATCCTATAGCAAAGAAGGAGCCACACGACAGGGGTAACCTG
+
===AAAAA<+?A777<@=AC+<A))1)0:?=>)95ABA*=*/=83.<AAA=A95(-;@@@??;765(>(.;=?9>=359;589;299-95;<0&&09;;:2
@66H
CATACCAGATAGCAGCTACCCCATGGACCACAGATTTCGCCGCCAGCTTTCTGAACCCTGTAACTCCTTTCCTCCTTTGCCGACGATGCCAAGGGAAGGAC
+
CCCFFFFFHHGHGIJJJJJJJJJIJIJJJJJJJIJJJJIGIJIIJJJJJJIIIJJJHHHHFFFFFFFDECEEEDDDDDDDDDDBD>@BDDDDDDDBDDDDD
@66I
CTAAACTAGAAGGTCAAGTAGAATCTTATAAAAAGAAGCTAGAAGACCTTGGTGATTTAAGGCGGCAGGTTAAACTCTTAGAAGAGAAGAATACCATGTAT
+
@C@DDDFDD??FFGGFIGIIG@HHGIIIIIGGII8BFCHCHGIIIGICBGIIGHECHID<FHCGI>BBC?CDDDDCCCCDDDDCDBCDCCC>>CCCCC:@:
@66J
TATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACGGCCAGCCTGTCCAGGGGTATGG
+
@CCFFFFFHGHHHJJJIJJJJJJIJJJJJJJJJJIGIJIIJJIJJJIHIJJJJJJJJJIJHHGHHFFFDDCBBDDCDDDDBDDDDDDDDDDDDDDD9BDDD
@66K
CTGGATGACCCTTCAAATTCTCATTTTATTGCCTGGACTGGTCGAGGCATGGAATTTAAACTGATTGAGCCTGAAGAGGTGGCCCGACGTTGGGGCATTC
+
@@@FBDDDFFHHGGHHGIAHFHGCHHIIGGHJJGHIGFBGIGHIIJIJADACGHGHGIJJJDAHGIIHCEHC@@@@C>A6;ABA??BBBD???@9>99@@
@66L
GGAAGAGGACAAGTGCAAGCCTATGTCCTATGAGGAGAAGCGGCAGCTCAGCTTGGACATCAACAAGCTCCCCGGCGAGAAGCTGGGCCGCGTGGTGCAC
+
CCCFFDFFHHHHHHHIJJJJJJJJJJJIJIJJIJJIGJJGGGIIIJFJCFGGHGIJGHHGEHFEFFFDEEDDDDDDDDDDDDDDDDDBDDDB9@D8?CCD
@66M
GGTCTCTGTCTCCCCGCCTGAAGAGCACGCCATGCCCATTGGGAGAATAGCAGACTGTAGACTGCTTTGGGATTACGTCTATCAGTTGCTTTCTGACAGCC
+
<??ABDDDFDFF??F@F@FFB9F?BFBDBGHEEHGII<;BFGH=;FDCEGIGG7CAEHCC=EE>BDEEEDCCCC;A@=ACBECCC@;A>@CCCCCDCCC?B
@66N
AAATCTTTAAAGCAAGAGAAAGAACAAGTTTCATTGAGATGTAGAGAGCTAGAAATCATTATTAACCACAACAGGGCAGAAAATGTACAGTCATGTGATAC
+
CCCFFFFFHHHHHIJJJJIJJJJJJJJJEHIHJIJJHIJIIBDGIJJIJJJJJJJJJIJJJJIHJGGIJIGHJIGGFH>BFFEDD;BDCD@ACDDCDDEED
@66O
AAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACC
+
@CCFFDDDFHGHBFHGJIIIJJJEHGDHHIJGIIJJIJGIIJICCFGGEHJJJFGIGIJJFIGDEHEFGADFFFDDCE@CC@A;?=AC:>CBCACCCDCCD
@66P
CCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGT
+
CCCFFFFFHHFHHJJJJJJJGIJJJJJJJJJJJJJJJJJJJJJJIJJJJJIIHEEHHGFFFFDFEEEEEDDDDCCDDDDDDDDDDDDDDDDDDDDDDDDDC
@66Q
CTTGGTTCTTGGAAAAACTCTAGGAGAAGGCGAATTTGGAAAAGTGGTCAAGGCAACGGCCTTCCATCTGAAAGGCAGAGCAGGGTACACCACGGTGGCCG
+
C@CFFDFFGHGHHIJJJIJIJJJJIIEHGGIIGIIIIIJBFHJI?FGEGHGFHGJIJJJHFFFDECFDEECCDDDDDD@DCDDDD3>CCDDDDDD2?BBDD
@66R
CTTCAGTATGCACAGACCTCTGATGGACAGCAGATACTTGTGCCCAGCAATCAGGTGGTCGTACAAACTGCATCAGGAGATATGCAAACATATCAGATCCG
+
CCCFFFFFHDDHHJJJHGIJJJCIJIJIJIIJJIIGIJIIFEDHGJFGIIJJIJJDFGHIJGHJJJJJHFHHHHFFFEDDECECCEDDDDDDEDDEDDDDD
@66S
GCAAGAGAAGTGCATGGTGGGCAGGAGCAAGCCCTAGATAGCCCCAGAGGGATGCACAGGGATGGGAACACTCTGCCATCCCCCAGCAGCTGGGACCTGC
+
CCCFFFFFGHFHDGGIJ<CGGIIJJIJJIIIJJJFIJJJJIIJJIJIJJJIGGIJJIEHHH?BBFDDACDDDDDDDDDDDDDDDDDBCDDCDDDDDDDDD
@66T
GGGAGACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTT
+
CCCDFDFDHFDHHIJHJHIIJJIEHIFHJGGIJIIIJIJJJIJIJHHHFFFDDCDDDDDDEEDDDDDDEDDDDDDDDDDDCDDDDDDDDDDDDDDDCCDED
@66U
CTCCTTTCCTCCTTTGCCGACGATGCCAAGGGAAGGACGTCCTATGTACCAACGCCAGATGTCTGAGCCAAACATCCCCTTCCCACCACAAGGCTTTAAGC
+
@C@FFFFFGGHGHJJIJEBGHGBGDHGGGIJJIFEGIIFGHIGHGIGIIJG9EHHFFD@CC@CCDCCDDDDCABDDDDDCDDDDDDDBDDDBDDDDDDDDD
@66V
GCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCC
+
@CCDFFFFHHHFHJJHIJIJJJJJIIIIIJJJGGGIHHIIGBHGHIIJIJGEGHGIJJIJJIGIJJHHHHCECDECCCCDDDDDDCDDBDBCDDEDADDCD
@66W
CTACTGTAGAGCCCACACCTGGGAAAGGACCTAAAGGTGTATATCAAATCAGCAAACAAATCAAAGCTCATGATGGCAGTGTGTTCACACTTTGTCAGATG
+
@@@FFFDDFHFDDIJIJJIIIGIIJIIIHDHIJGHIJ:BBDFHIIIEIIHHJJJIEGIJJCFHIIDIGGHFHEFFFFFFDE;A>CCDDDDDDDCCDEDDDD
@66X
CGTCCATGTACAAGTACCCTTCTGACATCTCCTACATGCCTTCCTACCATGCCCACCAGCAGAAGGTGAACTTTGTCCCTCCCCATCCATCCTCCATGCCT
+
CCCFFFFFHHHHHJHHIJJJJJJJIJJJJIJJJJJJJJJJJJJJJJJJJJGIJJIJJJJJJJJJJJ@HIJJIJJHHHHHDFFFDECEEDCDDDDDDDDDDD
@66Y
AAAAGCACAAAAGGAAAGAGGAAGTGGAAGAGAATAAAAAAAGCAAAGCCAAGGAACCTCCTCCTAAAAAGACGAAGAAAAATAATAGCAGCAACAGCAAT
+
CCCFFFFFHHHHHJJJJJJJJJJJGHIIJJJJJIJJJJJJJJIJJJJJJJJJJIJHHHHFFFFEEEEEEDDDDDDDDDDDDDBDDDECCDDDDDDDDDDDD
@66Z
TGAAGAGGTGGCCCGACGTTGGGGCATTCAGAAAAACAGGCCAGCTATGAACTATGATAAACTTAGCCGTTCACTCCGCTATTACTATGAGAAAGGAATT
+
CC@FFDFFCCDFFGIGIGEBFGGGGFHGCGBHIJJIJFDAGFEEEGGHGGFHGFFFFEDDFCEDEEEDDDDCDDCDDDC@BBDECDDEDDDCCCDDDDDD
@670
TCATCATCAACCAAGAAGGAGAATATATTAAAATGTTTATGCGCGGTCGGCCAATTACCATGTTCATTCCTTCCGATGTTGACAACTATGATGACATC
+
@;8B=;AB?FDHDGHFHGICFBFFAHHGBBHIEGG1?DFBGGEGEGDFAAGIH=?EHEEEEEEEDEEDEDCCCC>8<??@CC::ABCC@@ACCDCCCC
@671
TTAAACTCTTAGAAGAGAAGAATACCATGTATATGCAGAATACTGTCAGTCTAGAGGAAGAGTTAAGAAAGGCCAACGCAGCGCGAAGTCAACTTGAAACC
+
@@@DFFDFHHHHGJEHGIIIHIGJJJIGEEHIIJIIIGIJJJIIIFDBGHIIGGCHGBH<BBFDEICEGDG9FAGAHHFD<>BB>=BBDCDDCDCDDDDDB
@672
CACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCA
+
@@@FFDFFAFFHAHIIIJGGIIJJIGIIJHHJGGHHIIICGHIIIJIIIGIEGIIHIJGEEHHEHHFFFFFDCCCDDDCDDBC<ACDCCDDEDDDCDCDD
@673
AGGATACCTGTCTCCAGATCTCAGTAAGGTACGGAGTAACTGTCCAAAAGCCATGAAGAGATTAATGGCAGAGTGCCTCAAAAAGAAAAGAGATGAGAGAC
+
?;1=:=B+=D<C?C:AEFACEFDF?FAEFHEH@6?CG?FAGC9DFEGD@G;8DDB<B84=F;=C=FCEEED=?EE;=@@;?).;>5=?B>1=@:ABBB>??
@674
CAAGCGGTGGGCGGTACGGGGGGCGAGTCGGGACGAGGGTAGGACGTGGCCGGGGCTCTCCGGCCCTGGGGGGGGAGAAGTTGCCGGGGGAGGTTGGA
+
(((2<8=(:=:28((-<-((0-&616118)1&&)0)6-&((286(0)((&25--&00(586&&0&08;(+0&&)&)0&(((+((+0&050&5&((+0(
@675
AATGTACAGTCATGTGATACTCAAGTAAGCTCTTTATTAGATGGAGTTGTGACCATGACAAGCAGGGGTGCTGAAGGATCAGTTTCTAAAGTAAATAAA
+
@@@FDDDDDCFHFHBED@EFHGGGG@FHHGGIGIGIJIIJDHIIII@FGFHHJJFCGIJIGIGHFHIJ;AHHH>E>CD@;AA>@CEDDDAC>CCDDEDD
@676
AGTATCTAAACTAGAAGGTCAAGTAGAATCTTATAAAAAGAAGCTAGAAGACCTTGGAGATTTAAGGCGGCAGGTTAAACTCTTAGAAGAGAAGAATAGC
+
++=?7,22@ABB7A<+++?@A++<?7,?A@@=@>>=*?@):=7?AB<****09997**9*.)987))=5'4''355;:?>>=>>559=>><=?383(+(+
@677
CTTTCGCCAACAGGTTTCCTCTACACAGCACCGGACCATGTTGCCTGGGTGCACATTCAGAGCGGCACTATCACCTGGCTGCAAGTGCCCCTGGGTCCT
+
7(((((<-2=((2(:4)):))).28)).6)88/9--((0//..)<))((.-().38)8)6)))',',,,,(,5(7(85+((+(+(++((5+(+((3(8;
@678
CTGGAGACTCAGGTGGAGTCATGCTTATATGGAGCAAAACTACTGTAGAGCCCACACCTGGGAAAGGACCTAAAGGTGTATATCAAATCAGCAAACAAATC
+
@@@FFDDFHDHHH<EBGGEGGIIIIGJJIEHJEFEHGIEIEGIJIFEA>FHG6?DGCHIGIG=C@EH;A=AACFDF@A@CDDDCCCDDDCC@CDDD?BDAC
@679
GCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACC
+
CCCFFFFFHHHHHJJJJJJJIJJJJJJJJJIJJJJJJJJJJJJIJJJJJJJIJJJJJJJJJJJJJHHFHFFFFEEEEEEEDDDDDEDDDDDDDDDDDDDD
@67A
CCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTCCTCCCCTTGGAGGGGCACAAACGATCAGT
+
@@@DDBA?DF;DAEBFAB<+AC9B;DFFC??FAGDFFGFIEIA@FFFBBD@;9>BF3CFEFIIFFFDDDD7>@>A@?BB;@A:<<@>@@@9?BBB5<<93+
@67B
TTCACTTCTAAAACAGACACATGGTCCTTTGGAGTGCTGCTATGGGAAATCTTTTCTCTTGGATATATGCCATACCCCAGCAAAAGCAACCAGGAAGTTCT
+
@@@?DDDDDDD<FGGICDFG;B<BHIIBHDFGEFFGIIICGGEIGIFCCFDGGGIHG<@GCFAFDHDFAHGICH@GIFFEEDEB>;A@.6;;??A??::>>
@67C
TGCGGCGCCTAGAGGGAAAGCGAGAGGGAGACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCT
+
@CCFFFFFHHHHHIJJJJJJIJDHFHIIFHGIJIEEFFDDCEBCDDDD8?B=BDDDDDADBDDCDD@CDDDDDDDDBDBDDDDCDDDDDDDCDDDDCDB@C
@67D
CAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGG
+
CCCFFFFFGHHHHJJJJJJJJJJJJJJJJJJJIIJJJJJJJJJJJJJJJJJGIJJJJJJJJJHFHHFFFFFEEEEEEEEDDDDDDDDDDDDDDDDBDDDDD
@67E
CTCATACACCGAAACCTGACCGGGCCTTCCCAGCTCACCTCCCTCCATCGCAGTCCATACCAGATAGCAGCTACCCCATGGACCACAGATTTCCCCGCC
+
<:;BD:BDAD:@D:@;@A922CDDAA@@??)?*99DB>BCD;AC@AC4.;5?=?9@>@>AA(5,;;A>(:<(:><??<><>>:9><8<94:4:(4(009
@67F
CTTACATGAACCACATCATGGTCTCTGTCTCCCCGCCTGAAGAGCACGCCATGCCCATTGGGAGAATAGCAGACTGTAGACTGCTTTGGGATTACGTCTAT
+
@C@DFDFFGDHHFIIJGGIIIHIJJJJJGHEHIJGGIIJIIJJGIHJIJIIIIGHIGCHIHHGFEFFFFEEEEECCC@CCDDDDDDDCCBDDDDDDBACBC
@67G
GTGAAGAGGAGCCAGGGTCGGATTCCAGTTAAATGGATGGCGATTGAATCCCTTTTTGATCATATCTACACCACGCAAAGTGATGTATGGTCTTTTGGTGT
+
=:=14=DDBFF=:EEF?E@C:)1:?19:DB?G9:::*00))(7@@;=@==7=.=@@E4?7=7;7;77766;A2(,',8?5,55>5@4::@B::AABA<B?8
@67H
GGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGC
+
1=??A:?D:CF8FB>FF4<?F:3C<:9C9C?):CABGFAFCDCF@/==BFBCCFC@AE68?B@==B?BBBBBB>A@A:@:A?A?B<?@>???12@B>(+8?
@67I
TCACAGTAAAAATAGGTGATTTTGGTCTAGCTACAGTGAAATCTCGATGGAGTGGGTCCCATCAGTTTGAACAGTTGTCTGGATCCATTTTGTGGATGGC
+
CCCFDDFEFDHHHJIEAEFFHJJIIGGHIIJIIJIJIJJIGHHHIGHGHIGI3EGI@@GEGIGIGGIIJIIGGEEECEEFFFEFFCCEEDEC;AB>CCDD
@67J
GGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAG
+
@@@DBD?;D+CAFB<GGHG@FGCFGGHFAGCEC?GGGIDGIIFGGF9D@DHIIBFF8)=8=@CGIFHHE>BDECC>CCCCCCCCBBCBB>CC@CC
@67K
CAGCGAGAAAGGAAGTCATCTTCATCCTCAGAAGACAGGAATCGAATGAAAACACTTGGTAGACGGGACTCGAGTGATGATTGGGAGATTCCTGATGGGC
+
@@CFF@DDHDHHAHIIFIEIJJGDHIJEGIEHIIIGICGGIGIIIJJJIIIHIJJJGIGFEHEEHIHEDBDDACAA>;>C>BCDDD?;CCDEDDDDDDDD
@67L
ACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGGGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCT
+
=?8:?:::=++A:EC81+???E@B<DE@3B16BD08?9B><<'-=)7(.=;;C(58<?;(66;;>;5;??9,:((5:>>;:>AA><??>?><2++2488<
@67M
CTGTGTTGTCCCAGAAAAATTCGATGGTTTTTCAAATGTTGCCCTTTCTGTAATTATTTTAAGAGGTATATGTCTCTCTACTGACCATAGGAGACATCAA
+
B@CDFFFFHHHHHJIJJJJJJJJJJIJHIIGIJJIJIIIJJIJJJJIJJJFIIJJJJJJJJJIJJJEHGIJGJJIIJJHHHHHHHFFFFFEDEDDDDDDD
@67N
CCTGAAGACAGGCCCAACTTTGCCATCATTTTGGAGAGGATTGAATACTGCACCCAGGACCCGGATGTAATCAACACCGCTTTGCCGATAGAATATGGTCC
+
@@@F;;DDDFFBBIIIE@FHCEFH@FCDEGDH@GBF9BGDDC@F*BBBFG43?FGEGIIGIGHH499>C;;;@CCCBB?8/=<CC:<0599C<ACDDCC>>
@67O
CACAAAAGGAAAGAGGAAGTGGAAGAGAATAAAAAAAGCAAAGCCAAGGAACCTCCTCCTAAAAAGACGAAGAAAAATAATAGCAGCAACAGCAATGTG
+
CCCFFFFFHHHHHHIJFHIHHIHIJGHIIJIJJJJJJGIJJJJJIJIJIIJIJJHHHGFFFFFFEDDE@@DBDDDDDBDDEEDDDDBDDDDB?CDCCCD
@67P
CCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTT
+
@C@ADFDFFF?;>GGBGIIEGHHHEIIIHIGGGEHCFHIIIIIIIIGHGG@DAHHHEHHDEFFDD@CCDDDCCCCC5ACBDDCDDCDDDCDDCCB@DB0<
@67Q
CTGAAGCAGAGGAAACCTCGGATTCTTTTTTCACCATTCTTCCACCCTGGAAACTCTATACACACACAGCCGGAGGTCATACTGCATCAGAACCATGA
+
@@@DDFFFHDHHFIGJGIGGIGIIJIIIJIJHGHIIIJJJJJJJJJJIJIIGGIIJIIIJIIJGHHFDFFDDDDDD<CACEDDDDDCCDDDDDDDDDD
@67R
GACGGTTTCGCCGGCAGTCTCGATGATAGTATTTCTGCTGCAAGTACTTCTGATGTTCAAGATCGCCTGTCAGCTCTTGAGTCACGAGTTCAGCAACA
+
CCCFFFFFHHHHHJJJJIIJJJCIJJIIJGHIIJGIJJGIJJJFFGIGIJIJJJGJJJJHEHHHHFFDDEEEEDDDDDDCD@CDDDBDDDDEDCDDDD
@67S
CTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTT
+
@?@FDDDDDAFFHIB@DCFHGHD>AAFEHAGHIGGGIIECHIEHDHGIBEHGGIGIGFDHIB@HIIAEAEHFFBB?C:@CACCCA@CCC;?AB@BB>@C@>
@67T
GAAAAGGGTACACTTGAACAAGAAGTTCAAGAATTACAACTTAAAACAGAATTGTTAGAAAAACAGATGAAGGAAAAAGAGAATGATCTTCAAGAAAAATT
+
@@@DFFDDADDHFGHIGIHJGJGIIEFBFGGBGGGGIIEEGGGJJGGHGGGGHGHGIIGHGHIIJIEHG@EGJHGHHEBEFDCEEECADC>CDCCCCCBDD
@67U
CAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATG
+
@@@ABDDDDFFD7A2+A<CIF7@8C2CDG@GEIGDFIIF8BBDCF??@3B>;DFFFFIGFIIIAECEEFFDDDBDCCAD>CCBBB?AB@BBBBB<A>:ABB
@67V
CTGGAGCGCTATGTCACCTCCTGTTTGCGCAAGAAAAGGAAACCTCAAGCTGAGAAAGTTGATGTGATTGCCGGCTCCTCCAAGATGAAGGGCTTCTCGTC
+
CCCFFFFFHHHHGIJJJJJJJJJHHIJJJJJJJJJJJJJJJJGIJJJJJJJJIJJJHHHHH>BEEFFFFDEEDDDBDDDDDDDDDDDDDDDDDDDDDDBBD
@67W
ATCAGATCCGAACTACACCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATGACATCTCCTGTGACTCTCACCTCTCAGACAACTAAGACAGATGACCCC
+
?@@B;DDDHD?FABBFGGIHIGGIIIGICGG@?DGGHEHIGHADHHII??FDFAC@==FHGCHCFEGHIDGBEHHCC?C?BCACACCCAC5>?>@>CC:@@
@67X
CAAATTCGAGCATCACCTTCTCCCCAGCCCTCTTCACAACCTCTCCAAATACACAGACAAACTCCAGAAAGCAAGAATGCTACTCCCACCAAAAGCATAA
+
CCCFFFFFHFHHHJJJJJJIHIIJIIIJJJJJJIIJIIJIJJJIJJJJJJJJIJJJJIJJJJJJJEFHHHFFFFFEEEEEEDDDDDDDDDDDDDDDDDDD
@67Y
GAACAGGGAAGCAGCTCGAGAGTGTCGTAGAAAGAAGAAAGAATATGTGAAATGTTTAGAAAACAGAGTGGCAGTGCTTGAAAATCAAAACAAGACATTG
+
CCCFFFFFHHGHHJGGJJGIIHCGHIHHIJJJJHGHHIGIIHIIJJIFGIIIIIIHJIIJJJGGHG?E7?BEFD3>ADCABCDD@;>ADD9AB9<?CDDC
@67Z
TTTTAGAAGAAAAGTGTGCTCTACAGAGACAGCTTGAAGACCTTGTTGAAGAATTGAGCTTTTCAAGGGAACAGATTCAGAGAGCTAGACAGACAATAGCT
+
@@@FDBDFHFGFDFGH@FIGIIIJJIJFGHIIGJIGGIIHHGHGGIJIJIIHJJJIIIJJJIGGHHIIGGHAEHEHHHHFFFCFDCEEC@CDCDDDCCC<@
@680
GCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTGAGTTGC
+
@;?DAAA?FHHFHIIACAIIGIIHGEFGGICGG;BFHEHIB<DEHGEICDHEDCHH;FFDHH;DGAEHFHDCDDFECBECCCBBBB;;<ABCB(44>>CCA
@681
CTCGATGGAGTGGGTCCCATCAGTTTGAACAGTTGTCTGGATCCATTTTGTGGATGGCACCAGAAGTCATCAGAATGCAAGATAAAAATCCATACAGCTTT
+
CCCFFFFFHFHHHIGHJJJJIIGGIIJIJIJIIIIJIGIEGHIIJJJIJIDHIHIJJGHGIIIIIIAHIJHHFHHHFFFFFFEEEEEDDDDDCDCCDCDDD
@682
CCTTATTCAAACATCAACAACAGGGACCAGATAATTTTTATGGTGGGACGAGGATACCTGTCTCCAGATCTCAGTAAGGTACGGAGTAACTGTCCA
+
@@@FFABDBFDFBD>CEBGHCE@BA1E@FFA:C?91?998BFEBF?F=BEHII6.=C?CA).=3?;);)(.;;>A@CC@C3>?@7',,:@:@4>44
@683
CTGAGGTTTGCCAGCAGCCAGTGTACATTCCGAAGAAGGCAGCCTCCAAGACACGGGCCCCCCGCCGGCGTCAGCGTAAAGCCCAGAGACCTCCTGCTCCT
+
???DDBB32<D:AC:CEDCEIAF2ABEFCC<9111)09BD@=)?89?@DBD>C)55A=4?D99',,088>5>>&+0+(88>A8><<><9<<>>>?3>>>>A
@684
TAAGGGAAGAAGAATTTGGTGTTGATGATTCTTATTCTGAACAAGGAGCACAAGACAGTCCGACTCATCTAGAGATGATGGAAAGTGAGTTGGCTGGGA
+
@CCFFFFFHFHHHIIJJJIAFGHIJJJIIJIJJJJJJJJJJGIJJJJJJJJJIJJGJJGJIJIGGHGHHHFFDFBDCCDCEEECD>CCDDDDDCCDDDD
@685
AACAAATCAAAGCTCATGATGGCAGTGTGTTCACACTTTGTCAGATGAGAAATGGGATGTTATTAACTGGAGGAGGGAAAGACAGAAAAATAATTCTGTGG
+
@@@DFDDFHHHHGHIEHIIEGGGIJHEEFGGBDHHHCGHGBDHIDGI>DGFH9FFF>FGHHCGIGEHDHIGEI1;=>BEDED@CC?CCDDBDDEDCCD@AA
@686
TTATCGAATACGTTGTGAAGAGTTAGAAAAGGAGATCTCTGAACTTCGGCAACAGAATGATGAACTGACCACTTTGGCAGATGAAGCTCAGTCTCTGAA
+
=@@DDB;A+A<2A@:FC4A:+<CECH+2?9:?F?)?9:B44**:0998@:@F=(=)8C;)=7777).)?;7;;@DD;(6;;55>@35-5>,(55:AB>A
@687
GAAGACCTTGTTGAAGAATTGAGCTTTTCAAGGGAACAGATTCAGAGAGCTAGACAGACAATAGCTGAACAAGAAAGTAAACTTAATGAAGCACATAAGTC
+
?<?DBDDAHHHFACAEG>CEFGHIAFHGDGHGGHCHHEHHHDGC?FIIDBAFFDCHG@BFEGH;=C@@EHII;ACAA3?BEFCCCEE:ACC<?CCC@>:;B
@688
CTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGAC
+
B@@FFDFFHFAHHIJJIIIJJJJJIIIGDFDHGIGIIGIHIGIEIGIJJAHIJDGFGHEIEHECC@HEEEHFFFFEDCA>>BDDB@CDCDDEDDEEDDB
@689
GTGAAAATGAAAAGTTCTGTCTTTGATGAAGACAAAACTTTTGTAGCAGAAACATTGGAAATGGGTGAGGTTGTTGAAAAGGATACAACAGAACTCATGG
+
B@BFFFFFHHHHGJHIIGJIJJJJJJJJJJJJIJJJJJJJJIJHIJJJIJJJJJJJJJIJJGJJJFHIJJHIIIHHHHHGFFFFEDEEEDDDDDDDDDDD
@68A
GAAACATGGTGAGATTAGTTTTCTAAATGAAGAAGTTAAATCTTTAAAGCAAGAGAAAGAACAAGTTTCATTGAGATGTAGAGAGCTAGAAATCATTATT
+
@@@DF?DBFFHHGGG@CBECFHHIECFHHHHEGFAEDHGEEEIIIIG>FAFDGEGCBFGHIGBHGIIIG>FGHEGGGG@=AEC>E;CDFFCCEC>CDDE@
@68B
AAGGAAACCTCAAGCTGAGAAAGTTGATGTGATTGCCGGCTCCTCCAAGATGAAGGGCTTCTCGTCCTCAGAGTCGGAGAGCTCCAGTGAGTCCAGCTCCT
+
=;=AAA7A@=+A<@@B=+<<AAA7ABABC@B>BABBAA0?)8=ABBBBBBB>BABBAAABA;;AA<@@>;>>@>@,/38;8;?:?=?:=8:;;:388;8:8
@68C
CCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGAT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJIJJJJHHHFFFFFDEEEEDDDDDDDDCDDDDDDDDDD
@68D
ACCCACCAAAAAGAATAATCCTATAGCAAAGAAGGAGCCACACGACAGGGGGAACCTGGGGCTGGAGGGAAGCTGTACTGTCCCACCTAACGTTGCAACTG
+
;?;DBBD8BDDDD;A:2<?FBFEE9B<EEDE>ED>B3;1?DDC@DAAACDA'5<5=AAA=????????=9188>>>3::3>>>>A<52>A<8338>:A4(+
@68E
TGGATCTGGATCATTTGGAACAGTCTACAAGGGAAAGTGGCATGGTGATGTGGCAGTGAAAATGTTGAATGTGACAGCACCTACACCTCAGCAGTTACA
+
@@@DFFFFGFGHGDGHGIC>?FFHD@EHIJIIJBFII:DC@@GHG<BEAC9BG;FDFGCGGGA:8@FHIG<7@H@E@CEEFFF@C;>C>CC3;AACC:@
@68F
CCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATG
+
@@@DDDDDBAAFAH?EFGBBD?FHB?<2??C?@EEC<??<:BEGD=B;BFEHE8(8BF>FEE>:=?B;@BBACC@BA>>';?;?A<<<?@B@78++:A:AC
@68G
CCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTAT
+
8:=?;DDDFDFFFE3CEGFIFFG:E@;D=DFF*?*9?DA9<BFFBEFF@==-?2?;?@B;6;(6;>@>A>;5<9998=8?B<B@B3:ABBBBBBB?ABBAA
@68H
CGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTT
+
CC@FFFFFHHHDHIJJJGIHGHHIGIJJJJIHGHIIHHGIGIIJIIIIJIIJIHJIJJJFHFHFDFFFCEDBCDDDDCCDDDDBB8>CDDDDDDDDACDDD
@68I
AGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATG
+
@@@DDBDDFFHHGHGIIIIIDEBFCEHIICHIIFHGICFHFEGGEFGE@FGGGEGGGGGIGGGGGHGGF@CDFCEEDCCECCC@C@ABBBBBDBCDEEED
@68J
CTGAAAATGAGTTTTCTTTAAGGCCAATTGACAGCAACACGTTTGAAATGAATGGCAAAGCTCTCCTGCTGCTGACCAAAGAGGACTTTCGCTATCGATCT
+
@@@FDDFFFHHCFHIIIIIJJJIEHIJIIJGIGIHGGGIBFFC>DFHEDHGEEIGHIIBF@FFHIJJJJICEHE?EEDEDFCCCAACCCC?BB??CDDDDD
@68K
GTGGAAGAGAATAAAAAAAGCAAAGCCAAGGAACCTCCTCCTAAAAAGACGAAGAAAAATAATAGCAGCAACAGCAATGTGAGCAAGAAGGAGCCAGCGCC
+
@@@D;?:2AA?BCFFFI8<?;EGFFFGIIFIFGDDFFFAFFFFFIFA@@@@@ECEDBB@BCB6>3>@@BB?@B<B?BAAB@>@>BBBBBA?@?@?9<<<<B
@68L
ACTGAAGGACTGCAGCAGTTACAAGAATTTGAAGCTGCCATTAAACAAAGAGATGGCATTATAACCCAGCTCACTGCTAATTTACAACAAGCAAGAAG
+
@C@DDDDDGHHHHJGEIGHHIJIGHHGIIJGGGFHGIHHIIJJJIJJJGHIJGIJAEDHIJGIJJJJJJIC@EHG>EEFFFFFF<CECDD?BBDD?CC
@68M
CAAAGCTTTCCCCCTCCTCTGATGATTAAACAGGAACCCAGAGATTTTGCATATGACTCAGAAGTGCCTAGCTGCCACTCCATTTATATGAGGCAAGAAGG
+
@@@FFFFFGHFDHGGGGGFHEHIJGIIJJJJJJIJJJGJIIJIHEDGIIFIJIIIIGCHHAHGF4@DHGIEHHEHHEFFFFDEEEEACDDACDDBDDDDC@
@68N
TCCATGCCTGTCACTTCCTCCAGCTTCTTTGGAGCCGCATCACAATACTGGACCTCCCCCACGGGGGGAATCTACCCCAACCCCAACGTCCCCCGCCATCC
+
@@@FFDFFHHHHHJJIJJJIJJIJFGIIJJIIIIGIJJJIIIJJJJIJJJJJJJJJJJJJJHHFFDDDDBDCCCDDDDDDDDDDDDDDDDDDDDDBDDDDD
@68O
CGACGATGCCAAGGGAAGGACGTCCTATGTACCAACGCCAGATGTCTGAGCCAAACATCCCCTTCCCACCACAAGGCTTTAAGCAGGAGTACCACGACCC
+
1??BD6AD=?DA?DDEBGD@EBHGGGIGI9?FFB>8?@F;@BFHCG@C@DE3=DAE=AB@BBDCCC6>A:ABBBBBBA?CCCCCCCA?B(3:>>4<@B>>
@68P
AGGACAGCAAATTAATGACTTTACCCTTCCTGATGTGAACCTTATTGGGGAGCATTCTGATGCAGCAGAGCTTGGAAGGATGCTTCAGCTCATCTTAGGCT
+
CCCFFFFFHHHHHJJIJJJIJJJJJJJJJJJJJJJIJJJJIJJJJJJJJJJJIJJJJJJJJJJJJIJJJHHHHGFFFFDEEDEDEDDDDDDDDDDDEDDDD
@68Q
AGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACC
+
CCCFFFFFHGHHHJJJJJJJJJJJJJIJJJJGIBGGHIGIJIJJHIIJJIJJHHFEFFFFDEDEEEEDDDDDDDDDBBDDDDBDDDDDDDDDDDEDCCDDD
@68R
TTATCTTAGTCAGCGGCGAAAATCTAACCTCCTTCGCATTAAACTGTTTCGGTTTTTAAGGATTTGGCCGAAGTTTCTCGGAAGACACCGGTGGATAAAT
+
;<5;?)).)...)22-((1(0(0):).9(<)(.7)(;'-'))).33))8)5;=5=(3,((:((7((,(,,5&&(+++:(2+&+&(+(+20&)&)2++((+
@68S
CTATGTCACCTCCTGTTTGCGGAAGAAAAGGAAACCTCAAGCTGAGAAAGTTGATGTGATTGCCGGCTCCTCCAAGATGAAGGGCTTCTCGTCCTCAGAGT
+
@@@DFDFAHHHHHIIBFHFHFHBGGGGIIEIIIIIIGIIGEICGBCCHIICFGHGIAGIIIEEGBHDADCACDDCCDDDDCCCBDDBCCDBDDDDCDDDD:
@68T
GGGGTATGTCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATC
+
;1--95)2)2.@86822.).69>14@1:>)-8@>?8<?>9?=??=>8.56=?;6>1(7636;3)=8>3).<:>:=8.=1).6=13(-,(:;>?(,,:63==
@68U
GTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACT
+
CCCFFFFFGHHGHJJJJJJJIEHJJJIIIIGGIIIIJGIIJIIGIJJIHIFIIIIJJIIJIIIJJJJIHHGHFFFFEEEDCDDDEEDDDDDDDDBDDDDDD
@68V
CCGCTATTACTATGAGAAAGGAATTATGCAAAAGGTGGCTGGAGAGAGATATGTCTACAAGTTTGTGTGTGATCCAGAAGCCCTTTTCTCCATGGCCTTTC
+
1;;BDDDDFFBF>FH>>GIGHCGGCFBA@@BCDGA?C?DGHIEC*?0?6D?D4=CADEGEC;CGC(7@==(77?CE;@7@C62>@CCA;@A@>ACBCA:A@
@68W
GCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAA
+
CCCFFFFFHHHHHIIJJJJJJJJIJJJIGIJJJJJJJJJJJGDGGIIJFIJGHIIJJJJGIFHHHHFFFFFEDDEDDDCCDDDDBDDCEEDDDDDDDDDD
@68X
TCTCATTCTAATGATCAAAGTCCACAAATTCGAGCATCACCTTCTCCCCAGCCCTCTTCACAACCTCTCCAAATACACAGACAAACTCCAGAAAGCAAGA
+
@@@FDFFFHGHHHHIJIJIIHIJIJJIJIJJJJJJJJJJJJJJIGIJIJJGIJIIJJJJJJJIJIGIGIHHHHHHFFFFFEEEEEBCCDDDDDDDCDDDC
@68Y
AGAAACCCACAGCTGCAGAGATCTCTGTTCGAGTCCCTAGAGGGCCGGCCGTGGAAGGGGGACACGTGAATATGGCATTCTCTCAGTCCAACCCTCCTTCG
+
@@?DDDAFDFHHFEEGHGIIIIIIDHIIDG@FHEHBEGGI>GGIGGEHIIFHFF?CCC@BBBBB?@B<?BDC@DCB>ACCCC@CCCCCCCCCBB?8@CCCB
@68Z
GCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGT
+
CCCFFFFFHHHGHIJJHIJJJIJJIHHHIIIJIHIIIJJJJJIIIIJJJHIJJJJIIJJJJJJJJJJIHHHFFDEDEEDDDDDDDDDCCDDDDDDDDDDDC
@690
CCTCAGTCCTCACCATGCCTCAGGAGGTCAGGGCAGCCAGAGAGCATCCCACCTGCTCCCTGCTGGAGCAAAAGGCCCCAGCAAACTTCCATATCCTGTTG
+
=;+@?=AAB,?BBACBBBB9@CAA+?A<:==A>7?AABBBBB3==9>=.7A>A>AB3>AABBA>>>>@@@@@@>@=;;6;;===?=9=?????;:?????:
@691
CTGAAAATGAGTTTTCTTTAAGGCCAATTGACAGCAACACGTTTGAAATGAATGGCAAAGCTCTCCTGCTGCTGACCAAAGAGGACTTTCGCTATCGATCT
+
CCCFFFFFHHHHHIJIIJJJJJIJJJIJJJJIJJJJJIIJIIJJJJJJGIJJIJIJJJJJIJJIJIJIIJJJHHHGFFFFFEEDEDDDDDDDBBBDDDDBD
@692
AGGGAAAGCGAGAGGGAGACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGC
+
CCCFFFFFHHHHHIJJFHHIJJGJJIJJIJIJJJJJIIJHIHHHHFFFFDDEEDDDDDDDDDDDDDDDDDDDDEEDDDDDDDDDDDDDDDDDDDDDDDD
@693
CCTGGGGCTGGAGGGAAGCTGTACTGTCCCACCTAACGTTGCAACTGGGAGACTTCCGGGGGCCTCACTGCTCCTAGAGCCCTCTTCGCTGACTGCCAAT
+
?@@FDFFFHHGHHIJJJJIIIGIIIJIIJJIJGIIIIJEIJIJGIIIIIHIGIIJIIHGFDCBBDDDDDDDDDDDDDDDDDDDDDDDDBBBBDCCCDDCC
@694
CCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGG
+
@@@;A?BDA;+<ACF9<AC@FB;EF>FGH>GI@GACHF>?:996:?@>;?DBF?8BG<@ABHI4(=6;;BC:.6;;;;?';8?<(5<5?95(8+:A4ADC?
@695
AGGAAACCTCAAGCTGAGAAAGTTGATGTGATTGCCGGCTCCTCCAAGATGAAGGGCTTCTCGTCCTCAGAGTCGGAGAGCTCCAGTGAGTCCAGCTCCTC
+
@@@DDFDFFDFFHFGG@FEHEGFHH@HHHHGIIIJEHGGGEEGCGGGIHJIBEEGJIIGIGG=HFHFFFFFD>>AB@B@BB@C>CC:ACCACCDCCDDCCC
@696
AGATATTGCACGACAGACTGCACAGGGCATGGATTACTTACACGCCAAGTCAATCATCCACAGAGACCTCAAGAGTAATAATATATTTCTTCATGAAGACC
+
CC@DFFFFGHHHGGHEGIGIJJGIIIDIJIIIIJEIIIJJJGIIJIJIIFHIJGEEHIJJJGHHHFDDFEEEDCC6@CCDDEEDEDDDDEDDEDDDDCDDD
@697
CTCGAGTGATGATTGGGAGATTCCTGATGGGCAGATTACAGTGGGACAAAGAATTGGATCTGGATCATTTGGAACAGTCTACAAGGGAAAGTGGCATGGTG
+
BC@DDFEFHHHHHJJJJIJGIJJJJJHIJJJJIIJIIIIIJGIIIIGIJJIJJIIJIIGJIIJIIJJIJJHGEHHFFEFFFDECCDDDDBD;ADBDDDD@C
@698
ATGGCGTCCACGGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATAT
+
@@@ADDFFHHFADDGII?HEIDGGGIHGHHEH?F@FGBGIGGBFADHIIHHHHHEHFFFACDDBBDDDDDD?ACCC@CCDDDCDC?CABDDDDD@@BDCCD
@699
CCGGATATGAGCATGAAACCTAGTGCCGCCCTGTCTCCATCCCCTGCACTTCCCTTTCTCCCCCCAACTTCTGACCCACCCGACCACCCACCCAGGGAGCC
+
;@???ADBD,C?DD@@E>?FDDC?<?HBBE@D>:**09*99BGE;;(.848FCG;@E:=EIF':>'(;(;@CC;>C?(8;'&)00&2?B?B<528()+5&2
@69A
ACCATCATGACCGACTACAACCCCAACTACTGCTTTGCTGGCAAGACCTCCTCCATCAGTGACCTGAAGGAGGTGCCGCGGAAAAACATCACCCTCATTCG
+
C@@FFFFFHHHFHHIJIJIJJFIJDHDHIECGBDBFHIEGFHJFIJEGHGHCIJGGIHHHH<EEFFFFACDDD5?CCBBBB@>@CADDDD@CDD@BBCDCD
@69B
CAAAAGATATGCTTACAAATTTGACTTCCACGGCATTGCCCAGGCTCTGCAGCCACATCCGACCGAGTCGTCCATGTACAAGTACCCTTCTGACATCTCCT
+
1==<7?<+?>27,<A<<CB>AA<3+3?,22<A4::4?A=ABBBA))=**=7*87AAA=ABAAAA'9',5,,8;=:>9=??>?;;38:388:???78838:8
@69C
GAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTG
+
@@@DDDFFFFFADGG@GHIEGIDGGHHIGHGDCGGHHGGGGIGIGHIIBFGHEIIIEGGGCAEEHGGEFDCA@@BCDDDD??>@AC@CCD>?BDDDDDDDD
@69D
CTATGAGAAAGGAATTATGCAAAAGGTGGCTGGAGAGAGATATGTCTACAAGTTTGTGTGTGATCCAGAAGCCCTTTTCTCCATGGCCTTTCCAGATAATC
+
@CCFFFFFHGDHHIJIJJJGGHIJJI<CGEGGEHIGHHGGBHGHGIIIHCGIFDGGEHGHFHIJIJJC@CHFHHHFFFFDEEE@ECBCACDDDECCCDCAC
@69E
AGCTACCCCATGGACCACAGATTTCGCCGCCAGCTTTCTGAACCCTGTAACTCCTTTCCTCCTTTGCCGACGATGCCAAGGGAAGGACGTCCTATGTACC
+
CCCFFFFFHHHHHJJJJJJJJIIIJGJJIIJJJJIJJJIIIGIIJJIIIJJIIIJJHHHHHHFFFDFFCDDDDDDDDDCDDDBDDDDDDBDDBDDDEDED
@69F
GGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTAC
+
?<@DDBDDC@DAHHGGGGEGHGCDAFDGG?F<BFDG@G?FFGIGHHDBCCHFGH>G@AEBCA=9C@B??ABEEECEECCCCCB@BB@BBCCCA@@A>AC
@69G
TGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGG
+
@@@DDDADDCFHFGEGDHG<FGHIFDFCAGGHEEHI@DEGE>GDGFEGFEHGDHE?;??DECCA@>CCCCCCCCC>>A@CC5>AC>C>CCCCCDCCCB???
@69H
GAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCC
+
@@@DDDDEFAFF6GFCADFCHFF?DHGBG@GH@GHGIIJIIDDHGEDGIGHGGH;CDDCDCCEDECCBB@B?BDDDBBDDDD>@@CAC@ACDD>BDDBBDD
@69I
CTGGGGCTCTCCCAAATGCTCCACATTGCCAGTCAGATCGCCTCGGGTATGGTGTACCTGGCCTCCCAGCACTTTGTGCACCGAGACCTGGCCACCAGGA
+
@@@DFF@DDHHHGJJJIEGHGIJGGIEHGIGIHGGGHGIIIJJIIIJBFHIJHGIJJJBIIGHFFFFFFEEEEEEE;C>ACDD=BBBDCDD@BCDDBBB?
@69J
ATTATTCATAGATCCCGGTGACTTTTGACTCCTTGCCGTTGAAAATAGTGCAGCACTCCCGATTGTAGCCCCCATTGGTATAATAATTACATCACAAGCCG
+
:+=<=A=,?,<A,,2++<<)+++2++251=A>=?***):))8**=A***/**/).().)(:-;<;7A))).53'5;(5-(-(-(((:>?(9(55;998(+)
@69K
TGGTACTTGCTACAGAATGTGGCCAAGGTGAAGAAAAGTCTGAGGGTCCTCTAGGCTCCCAGGAATCTGAATCTTGTGGTCTGAGGAAAGAAGAGAAGGA
+
??@=BDDDBFCDHCDH<C?CBHBEDHIIIIIACHEH>@:?DBGGIE89D9B<DHCCGIGHHDHC@GGE>7AHFEHFCDE;BEEE@B>ACBCBC:<<A<AB
@69L
CCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCAC
+
@@CFFFFFHGGFFFHGIIGJJIJGGGIJIJJJJGIIJJGIIJIEHIEGIIIFIGIEHHHF9??ACAEECDDDDDAC@CCDDDCDCCDBDDDDDCCDDCCCD
@69M
AGAGTTAAGAAAGGCCAACGCAGCGCGAAGTCAACTTGAAACCTACAAGAGACAGGTAGTAGAACTACAAAACAGATTATCCGAAGAATCAAAGAAAGC
+
@@@FDFFFHHHHFGIIJJGIIJJIJIGGIHCHCHIJIJIJIIGCGHIGEFHHFFEFDECCCECCCCDDCDDDDD?A@CCCDDDBD<@CDCDDDDCDD@C
@69N
CTGGCAGATCTGCTGTCCCCAGAAAAACAGAGAGATCCCTTGGCCTTAATTGAGGAGCTAGAGCAAGAAGAAGGACTCACTCTTGCCCAGCTGGTCCAGA
+
@CCFFFFFHHHHHJJJJJJJJJIJJJIIJIJJFGIJJIIJJIIJJJJJJJJJIGHIIJJJJIJIJJIGHGHFFFFFEEEEDDDDDDDDDDDDDDCDDDDD
@69O
CACCTCAGCAGTTACAAGCCTTCAAAAATGAAGTAGGAGTACTCAGGAAAACACGACATGTGAATATCCTACTCTTCATGGGCTATTCCACAAAGCCACA
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJHIJJIJHHGJJJIJIJIJJJJGIIJIIHGHIJJIJHHHHGHFFFFEEFDEEEDDEEEDDDD?CDDDB
@69P
CTTCTATTTAGTCACGAAGAAGAGCTTTCCAAACTGAAGGAAGATTTAGAAATTGAACATCGAATAAATATTGAAAAACTTAAAGATAATTTAGGCATTC
+
CCCFFFFFHHHHHJJJJJJJIJJJJJJJJJJJJJJJDHIJJJIJJJJJIIIJIIJJJJJJJJJJIJJIJIJJIHHHHHFFFFFEEEDEEEFEDDDDDDDD
@69Q
TTTGAAAATATGACTGTTGGAGAAGAAAGTAAGCAAGAACAGTTGATTTTGGATCACTTACCATCTGTAACAAAGGAATCATCACTTAGAGCAACTCAACC
+
CCCFFFFFHHHHHJJIJJJJGJIJJJJJIHHIIJJJJJJJJIGIIJJJJJJJJJIJJJJJJIIJIJJCHHIJJIJJHHHHHFFFFFFEEEEEDCDDDDDDD
@69R
CAGAGATTTTGCATATGACTCAGAAGTGCCTAGCTGCCACTCCATTTATATGAGGCAAGAAGGCTTCCTGGCTCATCCCAGCAGAACAGAAGGCTGTATGT
+
@@@=DDDD?FF<DGEF>FF<CEA:+<AAE?FF?C*?EFD9CFF<D4BDGEFFB9BDDFF;BFIF:FCF4=A(=DCEFFA.?(7;;.;6>>BB?(59,:5,;
@69S
GCCAAACAGCCCCTTCCCCCCAGAAGACTGTAAGCAGGAGGACCTCGACCCAGGGCAGGAACACTGCACCATGGTGAGAAGCTCGGCCGGCCAAAGCGACC
+
(0(((.(2)(2(;(()...<((-61))06).9<=8:).00'-.6))-'--:((('79;,,,,36((72(,(77,56(2((((((&)-0&06)02(+()(&&
@69T
TATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAG
+
CCCFFFFFHGHHHJJJJJJJJJJJJJJJJJIJJJJIIJIIDIJIIJJJJJJJJJJIIIIEHGHHHFHHFFFFEEACCECEDDDDDD
@69U
CCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGAC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJIJJIJIIJJJJJJIIJJJIJHGHHFFFFFFEEEDDDDDDDDDDDCEDEEEEEDDD
@69V
GGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJHJJJJJHHHHHHFFFFEEDEDDDDDDDDDDDDDDDCDDDCDD
@69W
CTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJIJJIJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJHHHHFFFFFFEEEEEEEDDDDDDBDDDDDDDDDDD
@69X
CCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGT
+
@?@BDFDFFHHHBHGIIIGI?FHGGIIIIIGIIIIGGIGGB@FHGIGIIIIIE=AEHHDEEFDCCEECECCCC(;ACCCBBBB=B@C<ABCCCCCCABBBC
@69Y
CTTTAAAGCAAGAGAAAGAACAAGTTTCATTGAGATGTAGAGAGCTAGAAATCATTATTAACCACAACAGGGCAGAAAATGTACAGTCATGTGATACTCA
+
?@@FFFFFFGHHHIIIIHCGEEEHACDHGIIIFGGHIEGCDHIGIICGIGIEDGGEGGGGGCHICGIIIGGGIHHGFFFEF?CCEDFEAA>>C@CDC>@@
@69Z
GGAGAAATCAAAGTAGCAGTGAAGACTTTGAAGAAGGGGTCCACAGACCAGGAGAAGATTGAATTCCTGAAGGAGGCACATCTGATGAGCAAATTTAATC
+
1::4+=B2+A::A<C4A2AAFFDE9FEFEDDA>9C?EE)?@30BDDCDDDDDDD;=C9CE@A;A@4AEECA?D(68?@A>>65>5;>>;3:?AA>>AD>:
@6A0
GAAATAAAGACAACAAATGAAGTTGTTTTGGCTGTGGAGTTTCACCCAACAGATGCAAATACCATAATTACATGCGGTAAATCTCATATTTTCTTCTGGAC
+
@@@FBDFDHFHHGJGHIIJFCHHIIFCGIIGIEIFFHGIIJJGIIIJJIEGGGGIJJIGIIJJHEIJJIIHE>E3BB3>CCDCDDDCCDEEEDDDDCDDDD
@6A1
CCTACAGCCAAGCTCCAAATCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGAGGTTATGGG
+
5;;3-)9)(=83(@)2.=))))..2.9.@@)>???)9=3.(76.).6=33'-51(.=(>91)<>?8>?9,,,(9;<<85;5;,((+6222:(+&+82:;/2
@6A2
TCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATG
+
;??DDEFD>FDHHIGA;BFHFHGGGIIGIIIFBDGF@A@<'7=C@DCEEGA?CC=C>@;B77@C;@?A?CCCACCCCC@>>C:A@@?@B<?7A@@AB9AA>
@6A3
CAGGAGATATGCAAACATATCAGATCCGAACTACACCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATGACATCTCCTGTGACTCTCACCTCTCAGAC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJHIJJJJJJJJJJJJJJJJJIIJJJJJIJJJJJJJIIJDHIHHHHHHHFFFFFEDEEDEDDDDDDDDDDDDD
@6A4
GTCGTACAAACTGCATCAGGAGATATGCAAACATATCAGATCCGAACTACACCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATGACATCTCCTGTGAC
+
1:?D::;A2CD::CDC<EBFEFFC?@A@@FEB@BEA@:D*??DD1BDCD@DDEIE>CDEIEDCA7.=;=CC).?@DD>D;>@;>A>A:A;>>5>AA:>>;:
@6A5
ACTAGGACTAATTTTAGAAGAAAAGTGTGCTCTACAGAGACAGCTTGAAGACCTTGTTGAAGAATTGAGCTTTTCAAGGGAACAGATTCAGAGAGCTAGAC
+
CCCFFFFFHHHHHJJJJJJJJJJJJHIJJJJJJJJJJJIJJJJJJJIJJJJJJJIIIJJJJJIJIIIJJJJJJJJJHHHHFFFFFEEEEEEDDDDDDDDDD
@6A6
CCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTAT
+
@@<DDDDDBBFDA>GFHHIGG>F<FBCAEGGIGGIIEHIIGEGIGIEHGIIEHIIEEAFHHIGC;;;=CCEEEF@DECECEECCCCCCC?<=<A@9055<C
@6A7
TTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGC
+
@@@FFFDEHHFFFHIDEGIIIJJJJJJGHIIEIJIHGGEEGIIGJJGIIJEIGHJIJIJIIJIHEFHGFEFFFFEAECDDDDDCCDDDDACCCDBD@DD?B
@6A8
GGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCC
+
@@CFDDFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJIIJJJJJJJJJJJJJJJJJJHIJJIJJIHHHHHFFFFDEEEEDDDDDDDDDDDDDDDCDDDDDD
@6A9
CACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATG
+
CCCFFFFFHHHHHJJJJJJJIJJJJJIJJJJJJJJJJJJJJJJJJJJIHIJJJJJJJJHHFFDDEDDDDDDDDDDDDDDDDEDDDDDDDDDDDDDDDDDDE
@6AA
CCGTAGGGCATCCCAGTGATCTGTGGGCAGAAGGTTGCTTCCCATTGCTAGAAAGTGGTGATTCCACACTGGGGTCTTCCAAAGAAACCCTTCCACCCAC
+
@@@DFDFFHHHHHIJJFEHFHHIHIIFIIJJIGIBDHIFGFHIGHHGGGIGHIJJ<FH=FEHIEHIGCEFHHGFFFEEEECEEDDDDCDDDDCDDCDDDD
@6AB
CCTCCTCCTAAAAAGACGAAGAAAAATAATAGCAGCAACAGCAATGTGAGCAAGAAGGAGCCAGCGCCCATGAAGAGCAAGCCCCCTCCCACGTATGAG
+
+:?DDDD?FFBB?+@EBEE1AE?FFFFEFGFFC@DGFFBFFEF>FFFBFFA8B=FDFF@;9;C>;<<<39?=>@BA<9@BBBBBBB3<?2<<>@B(9:>
@6AC
CAAACAGTCCAGGCTCTCCGAGGACGGGCTGCATAGGGAAGGGAAGCCCATCAACCTCTCTCATCGGGAAGACCTGGCTTACATGAACCACATCATGGTCT
+
@@CFDDDDHBFHDHIGHIIGBHIIJGIFGJIGEGIJJGGJGHJIEGEHEHFFFFFEEEEEDDDEDDDDDDBDDC@CDDDBCDDECDDDDDDDDCDDDDCDC
@6AD
CTGTAACTCCTTTCCTCCTTTGCCGACGATGCCAAGGGAAGGACGTCCTATGTACCAACGCCAGATGTCTGAGCCAAACATCCCCTTCCCACCACAAGGCT
+
+1?B:BADBD<CCEBFFF>IHCEB?EGD<G=1<FBFF1?(?B;FE-;(;==CEEF)7=15=8>;;;ADB@>:>A959?B?BB3?BBB??94<B??BBBBBB
@6AE
CCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTAT
+
@<@DDDDDH:AFA?F@BCGAGCGGGG<<F3)BGF?9BG>>FDFA;A<AE2CHHEEDEEC>>>6(5@>>>5=39<?@BB?B?88AC@@CBBB?BBBB3<@C3
@6AF
CTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACC
+
C@CFFFFFHHFFHJJJJJJJJJIJIGEHJJJJJJIFHIIJJJEIJIJJJIJIIJJIJHHEDDFECEECDDACDCDDDDDDDDDDDDDDDDDDDDDDECCDD
@6AG
CTTGTGCCCAGCAATCAGGTGGTCGTACAAACTGCATCAGGAGATATGCAAACATATCAGATCCGAACTACACCTTCAGCTACTTCTCTGCCACAAACTGT
+
@@@D1BADFDFFFIIFEGI+AG@BF@FFFIECFI@FFEFFI@FGIEFFIEEFIEBCEFIBAAEEEEE<EDBDDDCCC@AC>ABBBBBABBBBBBBBBBABB
@6AH
TGATGACTGGACAGTTACCTTATTCAAACATCAACAACAGGGACCAGATAATTTTTATGGTGGGACGAGGATACCTGTCTCCAGATCTCAGTAAGGTACGG
+
CCCFDFFFHGHHHIJJFIIIJJGIIGJIIJJIIJGIIHIIJGGDHIIGIHHGIJHJIGIGCGHJ;@E<BDB@CCCC@CDCDDDDDDCDDCCDDDDD:ACBD
@6AI
CCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATGACATCTCCTGTGACTCTCACCTCTCAGACAACTAAGACAGATGACCCCCAATTGAAAAGAGAAAT
+
C@CFFFFFHHHHHJJJJJJJJJJJJJJIHHIEHHIJJJJJJJJJJIIJJJJJIJIIJJIIIJIJJJJJJIIJJJJHHHHHFFFFDDDDDDDDDDDDDDDDC
@6AJ
CAACGGCGAGGATCACTTCAGCTCTGGCAGTTTTTGGTAGCTCTTCTGGATGACCCTTCAAATTCTCATTTTATTGCCTGGACTGGTCGAGGCATGGAATT
+
CCCFFFFFHHHHDIJJJJJJIIIJJJJJJJGIJJIJJHIIJIIJJIJJHEFFHHFFFFEEEEEECDDEEEFEEDDCCDDDDBDDBDCCD<@DBDDDDCDDD
@6AK
GTCTGAGACTCCTGCTCAGTGTAGCATTAAGCAGGAACGAATTTCATATACACCTCCAGAGAGCCCAGTGCCGAGTTACGCTTCCTCGACGCCACTTCATG
+
@C@DDFDDFHDFHCHIEAFCFAC<HFFHEDEBHFFG@?FD?FFHFFE@DDBHDHIE@;=BF=FFF@=CC;?CBEDCC;6?;??;::>;@;9@><>ACCCD@
@6AL
CAGTTACCTTATTCAAACATCAACAACAGGGACCAGATAATTTTTATGGTGGGACGAGGATACCTGTCTCCAGATCTCAGTAAGGTACGGAGTAACTGTCC
+
1:?=AD4B?CB4CE<@?A@@EE9C<:<AEE>8?;;?;DDDEBBD>DADD?DDACB//;@:7=3?;A7?AAA;>>@A>>(;(5>AA,:,;?1;+94>DA>>>
@6AM
CAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATC
+
CCCFFFDFHFHDHGIHIGIHHHIIIIIHDHGIIJJJJIJJJIAFHIJIJJJJIHHHHFFFDEEEDEACCCCCBCCCDDDEDDCDDCDDC
@6AN
TGCACAGCCACAACTTGCGCCGGGTTTAGCATTCTTGGGAAAGGGAGACGTTCACACCGGAGACCCCGCTGGCCTACTCCTTCACTGGCGCAAAACTACTG
+
(((2264:::)(8(9)=1(;((((((77766<19:8<>>().((-=??(((-6)).),''','((,,'&)0&((++(+((++(((+8((&&&)&((+66((
@6AO
GGGGGTACAACCAGCCCAGCCTAGGATATGGACAGAGAAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCC
+
(((@(83:41.-@>55@(.(-;@1=?8);):33)7>9)6.))0)..93>8>?;-3-().)::8;/;???8=>=8<850-:77;;3(3(:;+6:772((+26
@6AP
TAGAACCTGTCAACATACTAGATGTTAAAGATGACTGTGGCCTCCAACTAAGGGTCAGCGAGGACACCTGCCCACTGAATGTTCATTCTTATGACCCCCA
+
?@@BDEDEFHHHHIGIIGJIEHIIJEHHIIGHGGIHGGICGGGHIGGIGGGIIJDHIG@GGGIGHCEAA@DEDCAAA@CDCDDD;@D;>CCACCDDBBDB
@6AQ
CAGGGACTTCAGACATTAACCATGACAAATTCAGGCAGTACTCAGCAAGGTACAACTATTCTTCAGTATGCACAGACCTCTGATGGACAGCAGATACTTGT
+
CCCFFFFFHGHHHJIJJJJJJJJIIJJJJJJJJIIJJIJJJIJIGJJJII?FDHIJJJJJIJJIJJHEIJJGIG@GHHEHHHFDEFFECDDEADDDDDDCD
@6AR
GGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCT
+
CCCFFFFFHHHHHJJJJJJJJJGJJJJJIIGHJHGIJJJJJJIIIJJJJJJJJIIJJBDHIJIHH>ECHFFFFFCDEEEEDDBADDCCDDDDCCDDDCDD
@6AS
CCACACTGCGTGAGCTGGAGCGCTATGTCACCTCCTGTTTGCGGAAGAAAAGGAAACCTCAAGCTGAGAAAGTTGATGTGATTGCCGGCCCCTCCAAGATG
+
@<7D?=BDD:CFFF@?B<<FEF1EDGGFGCDFI@GCA??D;<F<'-5=EAC@AC;ADDBDDCC:A>A=@B>>(,,,5;,(5;5,:5593&05<@8?A>B:A
@6AT
CTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGC
+
CCCFF>?DFHDFHAHIFHGHGGHGI@CBFFHGHIIFGIGIHHCB<FBFIIGGIEGGGGGHIGIIIFEHEFCDAD@CCCC@DECC>A@???CCCCBC@CCA
@6AU
TTTAAGGCCAATTGACAGCAACACGTTTGAAATGAATGGCAAAGCTCTCCTGCTGCTGACCAAAGAGGACTTTCGCTATCGATCTCCTCATTCAGGTGATG
+
@@@?7BDDBFBFB:CGEGEIIDAEGFHHFGIIIIIIIIIIIFGIICEHGGGB>AGGHCHIGAF=@EEE2=AHE;;B9==CB@B=@>:A?@CCA>CC5>AC>
@6AV
ATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATG
+
@CCFFFFFHGGHGEFHHJIIJGCGFGIHIIIJJBDGIJIJJDGIFCGGIJJJEEEHGIHIIIGIGGHDEFFFFDDC@BBCDDDDDCDCDDCDDDDCDDDCE
@6AW
CGTATGAGTCGGAGGAAGAGGACAAGTGCAAGCCTATGTCCTATGAGGAGAAGCGGCAGCTCAGCTTGGACATCAACAAGCTCCCCGGCGAGAAGCTGGGC
+
BCBFFFFFHHHHHJJIJJJJJJJJJJBGIGIJIJJJIIIJJJJJJIGIGGIJGGIIHFFDCECEDDDDDCCDDDDDDDDDDACDDDDDDBDDDDDDCDDDB
@6AX
CCAAGGGTGAGCTGGGGCTCTCCCAAATGCTCCACATTGCCAGTCAGATCGCCTCGGGTATGGTGTACCTGGCCTCCCAGCACTTTGTGCACCGAGACCTG
+
CCCFFFFFHHHHHJIIJJIIIJJJJJJJJJIJJJJJJJJJJJJJIIIJJJIJJIJHJICBHFH@@BCFFCCCEEDDDDDDDCDDDDA>CCDDDDDD@BDDC
@6AY
CTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTC
+
@@<DDDDFHADFHG@FEHGGII?EFFEHG<BGC>GGIEHAFFDHCECCHHIDI@B9=5CFGGA@CH7?EBFCCCC??;;ACCCCCCCCC?>CCACCCCCCC
@6AZ
CCGGATGGAGAGGCCAGACAACTGCAGCGAGGAGATGTACCGCCTGATGCTGCAATGCTGGAAGCAGGAGCCGGACAAAAGGCCGGTGTTTGCGGACATC
+
CCCFFFFF?FHHHJJJJJJJJJJJJJJJJJJJIJIJJIIIJFHIGJJIJHHHHHHFFFFFFEEEDDDDDDDDDDDDDDDDDDDDDD5>@DDDCDDDDDDD
@6B0
CTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTT
+
@@<D?DDDFHDHHI@GG?EHIEHGIAFEGCGHGHGGEGIGGIE@?DFHGGEIII>FHIGIIGIGGHEAEHHEEDECA@CCDD@>C>ACCC<BBB?9399CD
@6B1
CCTGAATCTACAATAATGAGAACTCTACATAGTGGAGAAATAACCAGTCATGAGCAGGGCTTCTCTGTGGAACTGGAAAGTGAAATTTCAACCACAGC
+
@@<DDDDFFHFDGGGGIDIECFEHGGIBHIEH?FBEBEHGEEHICGEB<GGCHHCBFHIEGHBGDHIIIIGIGCDCAEHH@?@DECCCCCACBBBBAB
@6B2
CCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATGACATCTCCTGTGACTCTCACCTCTCAGACAACTAAGACAGATGACCCCCAATTGAAAAGAGAAAT
+
C@@FFFFDHGFHFEGIEHIIJIGBG?>D?FEFEEFHIBBCG?DHC@FAGGDH@CHIIIIJJGICGEHIFEG@EAG>AECHEFDDBBBACCCDDD>5<?C?@
@6B3
CGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCA
+
@@BFFFFFHHHHHIIJJJJIJJJJJJJJJJJJJJJJIJJJJJJJJGIEHIJJDHIHHHHHFDDDDDDDDDDDDDDCDDEDDDDDDDDDDDDDDDDDDDD
@6B4
ACAAATTCGAGCATCACCTTCTCCCCAGCCCTCTTCACAACCTCTCCAAATACACAGACAAACTCCAGAAAGCAAGAATGCTACTCCCACCAAAAGCATA
+
?+:=B;DDFF>:FBC<CGBFD?:9C1A:)CFG;?9DGF@D;FBFD>FFFII@8.)8=)(@@E@3777=?=@.7?73@;..3>A>(;ABBBBBB?@>?ABA
@6B5
TATACGGCGCAGATGGGATGCTAGTTTGGTGGGCTGAAGNANAAGATTGGTTGCCGGTCGGGGAAAGGGAGGGAGGGGGGGGGTAAAATTTTGAGGGCTGG
+
(((-2<580((((.))().:2))0)9=?3:=(<()'(.<#(#((8((6;3)(,((3'3''35&&&((+6()56&&)&)08&&&&&(+(+(3(3((+()()5
@6B6
CAGCTGATGCCCAGCCCCATCATGCACCCTCTGATCCTGAACCCCCGGCACTCCGTGGATTTCAAACAGTCCAGGCTCTCCGAGGACGGGCTGCATAGGG
+
C@@DFFFFHGHGHJ@EHIJJIGGFIGGDHIIGHIIGGHGGIICHIIGGHGGFHGFDDD?ECCEEEDDDDCDD@><AAACDDDDBBBDBB@>B<BC:C@CD
@6B7
CAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCT
+
@CCFFFDFHHHFHGGJGJJIEHHIJJHIIIJJJJJJJIJJJHIGIIJIJIJJJJGJGBGHHHFFFFFFEEEDCCBCDDDDDDECDDCDDDCDDDCCCCBD
@6B8
GGTGTTTATTTGCATCCACCTGTCCAGTTGCTCTGCTGTCTTGTGTTTTTGCAGCCTCTACAACCCCACGTCAGAGTGTGGGATTCTGTTACTCTATCCAC
+
@@BDDFFFHGHHHJJIJJJJJJIJJJJIIJJJJJJEIIJJIJJHHFHIJIJJIIJJJJIIIJIJJJJIJHFHFFEFACCCDDADDCDEDDDDDDDDDDDDD
@6B9
GGCAGGTTAAACTCTTAGAAGAGAAGAATACCATGTATATGCAGAATACTGTCAGTCTAGAGGAAGAGTTAAGAAAGGCCAACGCAGCGCGAAGTCAACTT
+
CCCFFFFFHGHHGGJIHIGGIJIGIJJIJIIJJJIFHGIJJJJJJJJJGIIGHJJIIIJGIIIJJIJICHGIGIJJIJHHHHFFDDCBD@DDDD?@DCCCC
@6BA
AGGACCTCAAACAACAATGTATTCAGCTAAATGAAGAGATTGAAAAGCAAAGGAACACTTTTTCATTTGCTGAAAAAAACTTTGAAGTTAACTATCAA
+
CCCFFFFFHHHHHJJJJJJHIJJJJJJJJJJJJJJJIJIJJJJJJJJJIJJJIJJJHJJJJJJJJJJJJJJJJJJHHFDDDDDDDDDDDEEDDDDDDD
@6BB
GGACAATTTGATAACTAAGCAGAATCAATTAATTTTGGAAATTTCAAAGCTAAAAGATTTACAGCAGTCTCTTGTAAATTCAAAGTCAGAAGAAATGACTC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJIJJJJJJIJJJJJJJJJJIIJJJJJIJJJJJHHHHHHFFFFFFEEEEDEDDD
@6BC
GGTCAGCGAGGACACCTGCCCACTGAATGTTCATTCTTATGACCCCCAAGGAGAAGGCAGGGTGGATCCTGATCTGTCCAAGCCTAAAAACCTTGCTCCTT
+
@??DDD>DHDHHDEIGIGGEDHIJIGGIJGGIEDHHHBHEGECHIIHEGIIGIEGHGEECDD)5=?CC=CCCDC5:AACC>:?@CDCDDDDBDDCD@CDCD
@6BD
CTTGTGGAAGAGGAAGAGAAAGTGCCTGTGAGGCCCAAGGACCCTGAGGGGGTTCCTCCTCTCCTGGTCTCTCAACAGGCAAAACGGGAGGAGGAGCGC
+
@CCFDFFDFHHHHHIJJJJJJJHHIJJJGIJJJJJJJJJJJJIJJJIJJJJJEFEFFEEEEEDDDDDCDDDDDDDDDDDDDDDDDDDDDDDDDDDDBDD
@6BE
GAAAAGTTCTGTCTTTGATGAAGACAAAACTTTTGTAGCAGAAACATTGGAAATGGGTGAGGTTGTTGAAAAGGATACAACAGAACTCATGGAAAAACTTG
+
CCCFFFDEHHHHHJIJJJJJJJJGIIIJJJJIJJIFHGIIGGGIJIIIJJIIJJIIJHIJGJFHIJIJJIJHGHEFHFFFCFFCECCECDDDCCDDDDDDD
@6BF
AAATGGGATGTTATTAACTGGAGGAGGGAAAGACAGAAAAATAATTCTGTGGGATCATGATCTGAATCCTGAAAGAGAAATAGAGGTTCCTGATCAGTATG
+
CCCFFFFDHHHHHIJIIIJJJIIJCGIIJJJIIJJJJJJJJJHIJJIJJGHIIHGJJJJJJJJJIIHHHHHHFFFFFEEEEEEDDDDDDDCDDDDEDEEEE
@6BG
AAAAAAGAAAAGCACAAAAGGAAAGAGGAAGTGGAAGAGAATAAAAAAAGCAAAGCCAAGGAACCTCCTCCTAAAAAGACGAAGAAAAATAATAGCAGCA
+
CCCFFFFFHHHHHJJJJJJJJJJJJJIJJJJGGIIJJIIIJJJJJJJJJJHHHHGFFFFDDEEDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDECDDDDD
@6BH
CCAGCAGTCGCCTAGCCAACCCTGGAAGCGGGCAGATCCAGCTGTGGCAATTCCTCCTGGAGCTGCTCTCCGACAGCGCCAACGCCAGCTGTATCACCTGG
+
CCCFFFFFHHHHHJJJJJJJJJJJJIJJJJJJJIJJJJJJJJJJHIHHHHFFFFFFEEEEEDDDDDCDCDDDDDDDDDDDDDDDDDDDDDDCDEEEDDDDD
@6BI
ATACTTCTTAGGGACAGCCTCCCACTGGTTATACGACTCCAACTGCCCCGCATGCATACAGCCAGCCTGTCCAGGGGTATTGCACTGGGGCTTATGATACC
+
1++2<27,?<,2++2+<+?@+7AC;+?A**1*1*):)00**=***0*(('-''())777)))((;==>((-;;((3'''((,(,3(39(&&)2+3:?((+(
@6BJ
CAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCC
+
CCCFFFFFHHHHHIJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJIIGHHHHHFFFFEEDDDDDDDDDDDEDEDDDDDDDDDDDDDDDD
@6BK
AAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJIIIIJJJJJJJJJJJJJJJJJJJJIJJIJJJIJJHHGHFFFFFFFEFEDDDDDDDDDDDDDDD@CCDDEDDD3
@6BL
GACCTAAAGGTGTATATCAAATCAGCAAACAAATCAAAGCTCATGATGGCAGTGTGTTCACACTTTGTCAGATGAGAAATGGGATGTTATTAACTGGAGG
+
@@@FFFFFHHCFFHHJIIJJIEIJFIJJJJJIJJJJGGIJJIGJJIIJJJJJBF?FHIIGGIIJJJIGGGGIIHGGIHHFHHB@BEFEADEDEEDDDCDD
@6BM
CCTACACCTCAGCAGTTACAAGCCTTCAAAAATGAAGTAGGAGTACTCAGGAAAACACGACATGTGAATATCCTACTCTTCATGGGCTATTCCACAAAGC
+
CCCFDFBEHDHDHIGIGFIEHIBHGHIIHHGFFEFIIIDDGBF?BBFFADFAFG>BHEHBAAEA@@E?E7AECCFFFCDE@;;@@B?CDDCA>>>><AC?
@6BN
ACTTGGACCTTGCGGCGTCCACTCCATCTGACTCCCTGATTTATGACGACGGCCTCTCAGAGGAGGAGACACCGCTGGTGGACTGTAATAATGCCCCCCTC
+
1+1<A7+2<C=77A0)1100?=009>70==77/9/====B>7./>==5A493',,,;>??3;=(86;2(+++()0090;;==388+83:833;839;.9;;
@6BO
CCGTGGCTATCATAAACCTATGAGGCAACCAGCCAGAAGGTCTGAACGCAGGAACATACTTCATATTAAATAACCTAGAAGGCTCCCTTACCCTACTCATC
+
(7(-:3=56)8:>):4.;)).;4.4897>(1((-.(:<)().0:)0<>5/'-(8..<?0=8.)8:3=8)6.6);99=;(.339;;55;<0,:7;5285/::
@6BP
CTACAGTTATCCCCAGGTACCTGGGAGCTTCCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTT
+
CCCFFFFFHHHHHJJJJEIIJJJJIIIJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJIHHHHHFFFFEEEEEEEDDDDDCDDDDDDDDDDDE
@6BQ
CCTACCCTCTGTCAGTGTCTCCCATGGAGAATAATCACTGCCCAGCGTCCTCCGAGTCCCACCCGAAGCCATCCAGCCCCCGGCAGGAGAGCACACGCGTG
+
C@CFFFFFHHHHHIJHGHIHJJJIJJJJIJJIJJJIJJJGIGIGIIGDHIIJJIEGGIIJGJJHHFFDDEEDDDDDCDDBDDBDDDD??BDBCDABBDD>B
@6BR
GTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAG
+
@@@FDEFDHHHHGGGFHHIIIEIHHGJEFHHGIEGEIIFIIIGCGIGGGGIHEGGGIEHHEDFA?BA?BD@@BCCDDCBCDDDDC@CC
@6BS
GCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATG
+
@CCFDFFEHFFHGIJJGJJJJJJJGIIGGIEGGIJIJIHIGIIJGGIIJJGIGJAFHIIIJIHCGIGIHHHHHFFFFFDCA?BDDD?CCCEDDDDDCDDCC
@6BT
TACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTT
+
CCCFFFFFHHHHHJJJFHJJJJJJIJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJHHHHHFFFFEEEEEECDDDDDCDDBDDDDDDDDD
@6BU
GCGTTCGCAAGTGCAAGCCCCAGATGAATTACGACAAGCTGAGCCGGGCCCTGCGCTATTACTATAACAAGCGCATTCTGCACAAGACCAAGGGGAAACGG
+
@CCDFFDFHHHHHIIIJIIJGGIJJJJGIJGJIJEGIJDHGGJJJIIGIGFFFFDDBDDCDCDEDCDCDCDBDBBDDDEECDCCBB?ACC@?BBD<<?CBB
@6BV
CGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCC
+
BC@DFFFFHHHHGHHIGHIFGGJIJJJIHGGHHCHBHIJJJJJJGIJJGHHGHHFFFFFFEDEDDDDDDDDBDDDDDDDDDDDDCDCDDEDDDDDDDDDD
@6BW
AAAAAGAAAAGCACAAAAGGAAAGAGGAAGTGGAAGAGAATAAAAAAAGCAAAGCCAAGGAACCTCCTCCTAAAAAGACGAAGAAAAATAATAGCAGCAAC
+
@C@FFFDFHGHGHJJJJIJJIJIJGIJIIJHHIEHHGIIJJJIJJJJJJGIIIGGHHHGFFFFDDEDDDDDDDDDDDBCB@DDDDDDDBDDDDCCCDDDDD
@6BX
GAAGTGGAATTGCAAAGTAATAGGATATTTATATATGGGTTTTTAGTAATACTTGCAAAGTGCCCGCGTGTACTATTTAGTCAGGATTTTTCTTGAGGAT
+
++11=BA+2=+:+,2+2,,33:,<<++,,<++<+A+**)1))))))*0***0***0*0**09*8)-'''5';;?;>@37.((6>9;;->((-(,5(,<((
@6BY
CAGCAGAACAGAAGGCTGTATGTTTGAAAAGGGCCCCAGGCAGTTTTATGATGACACCTGTGTTGTCCCAGAAAAATTCGATGGAGACATCAAACAAGAGC
+
@@@FFDFFBFHHDEEBGBF@BEDFGEFHHAECEGHGIIGFGIGBBFGDGIGHGCACGIGC=@=@CH;AHHFEFFFB>AA=5>C?CD>@<@CCDCDDB?<BD
@6BZ
AGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCC
+
@C@FFFFFHHHHGJJJIJJJIIJJJJJJIJJJJJJJJJJJJHIJJJJJJIIJIJJJJJIJJIIIIGGHGFFFDDBBBDCDCDDEEEEEDDDDDDDBDDDDD
@6C0
CACGGCGAGAAGCTGGGCCGCGTGGTGCACATCATCCAGTCACGGGAGCCCTCCCTGAAGAATTCCAACCCCGACGAGATTGAAATCGACTTTGAGACCCT
+
??@BDD?A:F<FHDGGIIGIIIG:F.;@EGEHIEHFFFF;@DE<ACBBBBBCBBB<:<CCCCCC@ABCCBBB@B3599B@ACCCC@C@89?@CCC@BCBBC
@6C1
TTCATGGAAGGAATATTTACTTCTAAAACAGACACATGGTCCTTTGGAGTGCTGCTATGGGAAATCTTTTCTCTTGGATATATGCCATACCCCAGCAAA
+
@@@?DD?3CFA;BA<EA,3AIEFFHFA@EGIFCFBEFFFIIEEFCEEIF?9*?B?DA:?=2CF9F@@FFCEEEE)7=CA3=)=;;?;@)6;;==?=@BA
@6C2
GACTGGACAGTTACCTTATTCAAACATCAACAACAGGGACCAGATAATTTTTATGGTGGGACGAGGATACCTGTCTCCAGATCTCAGTAAGGTACGGAGT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJIJJJJJIJJJGIJJIJJGHFFFEEEECEDDDDDDDDDEDDDDEDDDCCDDDDD?
@6C3
GCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTAT
+
CCCFFFFFHHHHHJJJJJJIJJJJJJJJIJJJJJJJIJJFHIJJJJIEHIJJJJJJJJIJJJJIJJJJHHHHHHFFFFFDEEEEDDDDCDDDDDDDDDDDD
@6C4
CCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGT
+
CCCFFFFFGHHHHJIJIIIJJHGGJJJJIJIJJJJIJJJIGJJIJIGIIIIJJJJGHGIGGGGJJHFFDCDEEDDDDDDDDCDDDDDD<?BCCDDCB?>AC
@6C5
CGAGAAGCTGGGCCGCGTGGTGCACATCATCCAGTCACGGGAGCCCTCCCTGAAGAATTCCAACCCCGACGAGATTGAAATCGACTTTGAG
+
@C@DFFDDHHAHHAHEFFD<:BEHGIIBBDHCDBBDH8;@<BBHGCEEBBDEECECDDDC@CCCBBD@;05-59BDAA@CC@B?BB<CC@?
@6C6
CCAGTGAGTCCAGCTCCTCTGACAGCGAAGACTCCGAAACAGCATCTGCATTGCCGGGACCGGATATGAGCATGAAACCTAGTGCCGCCCTGTCTCCATCC
+
?@?BABB>?CCFHCHHGHGGIIIIAFIGBEF@GHGEBDHHIEHCBFBHFIEHGGIBEF?DCCBB8?@CACCCC>5>@AA?>::@CC&9BB@<>ACCCCC>A
@6C7
CTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGC
+
CCCFFFFFHHHHHJJJIJJJJJJJJJIIJJJJJJJIJJJJJIJJJJIJJJJJJJJJJJJJJIJJJHHHHFFFFFFEDEEEEEDDDBDDBDDDDDDDDDDD
@6C8
CTCGATCCGCCTGCCTGCGCACCTGCGCTTGCAGCCAATTTACTGGAGCAGGGGTGACGTAGCCCAGTGGCTCAAGTGGGCTGAAAATGAGTTTTCTTTA
+
>;;A;;<?7+<A7C?7C;A7AAAA*?4?AA;=B=BAB>;8)>7=8)).7==24'53;5;==(;5(,(5=((5,3(8(382;===?8(8(834:?;::=8(
@6C9
GCTACCAGCAACAGGGCTTGCCCTTAGAAGCCGCTACTGCCCCTGGAGCTGGTCATTACGAGGATACCATTCTGAAAAGCAAGAATAGCA
+
?@@DDBDDFHHHHIIGEGDACGDDDGIGHE>DHHIIGFGCHIGGBCCFACFHECEIDC>C7=B<C@C@@CCACC@;@@CB???<A>:@@@
@6CA
GTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTAC
+
C@CFFFFFHHFHHJGIJJJJJJJJJJIIJJJJIJ@FHIIIJIJHGIJJJJJJJIGHJJIJJIHIJJHFHHHFFFFEEEDED@CCDDDDDDDDDDDDDDDDD
@6CB
GTTGATTTTGGATCACTTACCATCTGTAACAAAGGAATCATCACTTAGAGCAACTCAACCAAGTGAAAATGATAAACTTCAGAAAGAACTCAATGTACTT
+
CBCFFFFFHHHHHJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIGIJJJJIJJJJJJHHHHHHFFFFFEEEEEEDDDFEFF
@6CC
GCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATAC
+
CCCFFFFFHHHHHJJJJJJJJJIJIJJJJGHIIJJJJJJJJJIJJJJJJJJJJJJIJIHHHHHFFFFDEEEEDDDDDD;BDDDDDDDDD@CDDDCDDDEED
@6CD
ATTCCTGATGGGCAGATTACAGTGGGACAAAGAATTGGATCTGGATCATTTGGAACAGTCTACAAGGGAAAGTGGCATGGTGATGTGGCAGTGAAAATGTT
+
@@@DFFFDHFFHHGGIIIIIEGHIGIIIIEHIJIEIBIHIJJJJJJJJJICIIIIJJJDHGIGIHIJJIIHGEHHFFDDF;@CCCDCD@CD=CADDD@CBD
@6CE
AAATAGTTTATTTCATTGCATCAGTAGTAGTACTATTTAATTATGAGGAGAGAACTCAGCGACACTACCTGGGCCATACAGACTGTGTGAAATGCCTTGCT
+
CCCFFFEFHHHHHJJJJJJJJJJJHIJIIJHJJJJJJJJJIJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJHHHFFFFFEEEEE@CABCEDDDDDDDDDD
@6CF
TGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJIIHIJJJJJJJJIIJJJJHHHGFFFDDEDEDDDDDDDDDDDDDDDACDCDDDDDEDDEDDDDDDD
@6CG
AGAACAGGGAAGCAGCTCGAGAGTGTCGTAGAAAGAAGAAAGAATATGTGAAATGTTTAGAAAACAGAGTGGCAGTGCTTGAAAATCAAAACAAGACATTG
+
@@@D;DDDD=FF@;EAGIIIFID1????:DG=@>D?FGDGFE9BD@FF8BFCCFAFGI<C:@CE;=?CE.;?;;@6>(.;>(>AB@>ABBB2<@(5?A(>(
@6CH
GGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTT
+
@@@FFFFFHGGHHJJJJIJJIJJJJIIJJJJJJJJJJJIJIJJJJJJJJJJJIHJJGHJJJJJJJJJHHHHHFDFFFFCCBBDDDDDDDCDDEDDDDDDD
@6CI
GAAAGAACAAGTTTCATTGAGATGTAGAGAGCTAGAAATCATTATTAACCACAACAGGGCAGAAAATGTACAGTCATGTGATACTCAAGTAAGCTCTTTAT
+
CC@FFFFFHHHFHIJJJJJHJJIJHJIIIGIJJJIJJJJJJJJJJIJJJIIIJJGIIJJJJJJJJJJJHJJJIHFHHHFHFDFFFFEEE;@CEDDDDDDDD
@6CJ
GTCATGTGATACTCAAGTAAGCTCTTTATTAGATGGAGTTGTGACTATGACAAGCAGGGGTGCTGAAGGATCAGTTTCTAAAGTAAATAAAAGTTTTGGTG
+
@@@FFFFFHHHHHIIJIJJIJIIJJJJJJJIJIJJJIJHIIHHGIJJJJJJJJJJJIJJJ;FHIJJIIJGHHHHFFFFFFFED>CEDEEDDDDDDEDBD?B
@6CK
CTCAGCTTGGACATCAACAAGCTCCCCGGCGAGAAGCTGGGCCGCGTGGTGCACATCATCCAGTCACGGGAGCCCTCCCTGAAGAATTCCAACCCCGACG
+
C@@DFFFFHGHHHIJJJIIHJIIJIGHGEGIIJJJJJJJJIIIHFD@BBB?CCDDCDDCDDDDCCCDDDDBDDDDCDDDDDCDC>CDCDDEDDDDDDDDD
@6CL
CACCTCTCAGACAACTAAGACAGATGACCCCCAATTGAAAAGAGAAATAAGGTTAATGAAAAACAGAGAAGCTGCTCGAGAGTGTCGCAGAAAGAAGAA
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJIJJJJIIIIJJJJJJHGJJJJJJJJJJIJJHHHHHFFFFFDDDDD>ACDBDDDDDDDDDDDD
@6CM
GAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJIJJJJHIJIJHHHHHHFFFFFEDDDEDDDDDDDDDDBDBDDDDDDDDD
@6CN
AGAGCTAAACAGAGAGCTGGAAGAAATGAGGGTTACCTATGGGACTGAAGGACTGCAGCAGTTACAAGAATTTGAAGCTGCCATTAAACAAAGAGATGGC
+
CC@FFDFFHHHGHJJIGHIIGCHIJJJJJGIJFGCHHIIIGIJJJJGIIHIDHIIIJIEIIAHEGHIGECHHHFFFFFFCCEEECDDDACDDDDDCDCAC
@6CO
ATAGAATATGGTCCACTTGTGGCAGAGGAAGAGAAAGTGCCTGTGAGGCCCAAGGACCCTGAGGGGGTTCCTCCTCTCCTGGTCTCTCAACAGGCAAAACG
+
;@?DDDDDFDD?FEFG9FHHA7+3<1A@@E>GFFGI9::BDFB9*00?@=DA=B1=FEECDEI7?B@89=>>@?B<ABBBA?>@(>(4>@<@@@?@??9?5
@6CP
AGGACGTCCTATGTACCAACGCCAGATGTCTGAGCCAAACATCCCCTTCCCACCACAAGGCTTTAAGCAGGAGTACCACGACCCAGTGTATGAACACAAC
+
CCCFFFDFHHHHHIJJGIJJJJJJJJJJEGGHIJJJJJJJJJJJJIJIJJJIJJJJJJHHHHFFFEFFEEDDD?CCCDDBBBDDDD@C@CDEDEDDDDDD
@6CQ
GGGAAGGACGTCCTATGTACCAACGCCAGATGTCTGAGCCAAACATCCCCTTCCCACCACAAGGCTTTAAGCAGGAGTACCACGACCCAGTGTATGAACAC
+
CCCFFFFFHHHHFIIIJIHHIGIIIJJJGIJJHIGGGIIIIJJIJJIJIJIGIIIJJHHHHFFFFDEEEEDCDDDBD<CDDDDDDDDDDDCDDEEEDEDDC
@6CR
GCCAAAGCTTTCCCCCTCCTCTGATGATTAAACAGGAACCCAGAGATTTTGCATATGACTCAGAAGTGCCTAGCTGCCACTCCATTTATATGAGGCAAGA
+
@@@FFFFFHGFFHGGGIGGHIBG4CHIIJGHH@EHICHGGB;F)BBBFEFGIIJGIGCGCHGFGG@EGEA=AAHHHFF>;@CECEEDDDCCC:@ABBB@C
@6CS
CTGATATAGTACAACGAATGGAACAAGAAACACAAAGAAAGTTAGAACAACTCCGGGCAGAGCTGGATGAGATGTATGGGCAGCAGATAGTGCAAATGAA
+
CCCFFFFFHHHHGJJJJJJIJJJJJJJJJJJJIJJJJJJIJIHJJJJJJJHJJJJJJIIJHHHHHFDDFEC@CEDEEEDDDDDDDDDCDD3@ACDDDDDD
@6CT
CTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGAC
+
@?@DDBDEHHHHFGHGGGFGHIGHGGGIGHIIEGGGGGIIEFGAHGHGGGGIGGIGHIIGIGADGHEEHFGEDDCECCCDD@BBDDCDDECDEECDC<@
@6CU
TGAAAAGTCACATAACTCTCGGGAAAATTCAGATGATAGCCATAATGAATTGTCGGAAATACCTTCAACACCCAAATTAATACCACAAGTTACCAAAACTG
+
;(((2=>6@<))<<))):>)((;(((@1==<3))):))):3)0;?=)>33)))03''7'86=)).));=>-==53..9=(689;(-(,(,(5(7207;(((
@6CV
CTTGTTTTTATGTCCTCGTCTCCCTTTCCATCTTTCACCCTCGACTGGACTCCCTTAAGCCCAGAGATCGGTTGAGGCCTGGCCCGTAGGCGTGGGGTACC
+
0(092286(@==.9))2(;(:=446>)6).6=)3)))):(((07(7(()()6=79))):...;;7()...5(',(9,(((((,(,')55(+)&&&&&)&+(
@6CW
CACAGACCTCTGATGGACAGCAGATACTTGTGCCCAGCAATCAGGTGGTCGTACAAACTGCATCAGGAGATATGCAAACATATCAGATCCGAACTACACCT
+
@@@D?D?BFFFFFIEE3CAEFF@;FHFCCDGECFICG@91:BBFF?9?8B:FFF;FGC@;=;==D>7);AE??>BDD;6;>@(;@AA>>B<@@B?A:>?>B
@6CX
CGTCCACACTGCGTGAGCTGGAGCGCTATGTCACCTCCTGTTTGCGGAAGAAAAGGAAACCTCAAGCTGAGAAAGTTGATGTGATTGCCGGCTCCTCCA
+
@@@D:BB3C<CBDFF;F3ACFABGEBE@DDDD>BFB0BDD?DAE<FBFAECCEEEEDDD;6;6;ABBBB5;(:5:BB@(5;5:;@AB>:9<>3<<(9AB
@6CY
ATTCAGCTAAATGAAGAGATTGAAAAGCAAAGGAACACTTTTTCATTTGCTAAAAAAAAACTTTGAAGTTAACTATCAAGAGTTACAAGAGGAGTATGCTT
+
CCCFFFFFHHHHHIIJIIIJJJIJJJJIIJJJIIJIJJJJJJJJJJJIJJIJJJIJJJJHFFFFFFEEEEEEEDDDDDDDCBDDDDDDDCDDBD?CDECEE
@6CZ
TGACATCATGGAATGGCTGGTGGGGACTCACTTGGCCACTGGGGAGTCAGATGGAAAACAAGAGGAAGAAGGGCAGCAGCAGGAGGAGGAAGGGAGGTATC
+
===AAAAABBABB>2A;CAC+<;04?AA;?A7=?A*=91=>BBAAA->BBB9;>77>>3A;>>;=(5(.;=;358289:9;;;;;90258;<=;(&)(++3
@6D0
CATAAAACGACCATCACCAGCTGAAAAGTCACATAATTCTTGGGAAAATTCAGATGATAGCCGTAATAAATTGTCGAAAATACCTTCAACACCCAAATTA
+
CC@FFFFFFDHGHEIIHIJJJJJIJIIIHIIJIIIIJJEIIGIJIIIIGHHIJJJJJIIJIIJEHHHHHFFCC?CBDDCBCDDDCDDDDDDDDDBBBDDD
@6D1
CGGGAGCCCTCCCTGAAGAATTCCAACCCCGACGAGATTGAAATCGACTTTGAGACCCTGAAGCCGTCCACACTGCGTGAGCTGGAGCGCTATGTCACCTC
+
@@@DFFDDAFHHFGGIJIGEHIHIJIIIGGHIIIBHHIICHGFHJIHGCAE>;?6??=ACAC>CB?DBDBA>@DDDB<-<?CCCD??39@BBDDEE<CDCD
@6D2
GTTTTTTCTAATCAAGGGGTTAGGACTTTGCTATCTCTGAGATGTCTGCTACTTGCTGCAAATTCTGCAGCTGTCTGCTGCTCTAAAGAGTACAGTGCACT
+
@?@BDFFFGHHBDGGCGGGCAGBEB?CHEGG<DHIGIJFGHGGF*?F<<FFBFHCGC73=CGEH=AED@AAE:?BCD>BDACEEEDA@>=(5>>;B::>>@
@6D3
GAAGAAAGTAAGCAAGAACAGTTGATTTTGGATCACTTACCATCTGTAACAAAGGAATCATCACTTAGAGCAACTCAACCAAGTGAAAATGATAAACTTC
+
=:=BBDDDDHBHFIGIGGEHG4?EDH>>FGHE>EFHEBFB9?DFBC<B@DGC@FAFC3=BADG>;>@;;C>CEIGEHFEEBDDCEECCCCCAC@CD3;;>
@6D4
CTCCTTGCCTGAAGCCAGTCAAGAGGCAGGGAGCAGAGGCAATTCCTTTTCTCCTCTGTTAGAAACCATAGAACCTGTCAACATACTAGATGTTAAAGATG
+
CCCFFFFFHHHGHJJJJJJIJJJJJJIJJJJIIIIIGHJIJJJJIJJJJJIJIIJIJJJJJIJJHHHHHFFFFFDEEEEEEDDDDDDDDDDDDDEEDDDDD
@6D5
CCTCAATATACCCTTCCTAATAGCAAATGCATTGCTAATTCTTACCGAACGAAATAGTCTATGCGAAATAGAGCTGCGCAAAGGCCCCAAAGTTTTAGTCT
+
<<<??).))2@)<)2):=:)@):))=))26..=);1.;1))2)2))((0(7=5'())))./)8=;;'-(.)..)6..93''3;(865'(((56(((+((5(
@6D6
GCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGC
+
?@?DD83AFH8FFBHEGHG<DHIGECGCHEH9FBFG=?3BGGII<F?<8B6@GBCCCD;;;;7AE@AEBD3?A>9?;@33>;5;C3>@53@C3:?@029>9
@6D7
CTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACT
+
@@CDFDFDDH;;FGHGGGGHIE?CHHGHHAHIEGGHIABGACBFGHIHIIHHII;DEEEEFCF?CE>ACCB;;C><?CCAC?59@CCCCC@DDCC>A@BBC
@6D8
AGTGAGAGGACGAGGCGTAGAAAACCAACCAGGAATGACAAAGGGCGAAGGGAAACGGCAGAGAGTAAAACAGGGAAGGCAGGAAAAAGGGGCAAAGGGA
+
((8(())2(<.((-2-(1:((.0))(0((0(.(((:)))/.8))(8'''''',38((('&)(((+5((+((2(((2(((((+&(((((&((&&&((+6(2
@6D9
CCCAGGTTCTTCAAAAGATAGATCCTGCATATTTTGATGAAAATTGGCTAAACAGAATCAAAACTGAAGTAGGAGATAATTGGAGGCTAAAGATAAGCAAT
+
@@@ADABDFBAFH@GGIDGCCGHGGIE3F9AA??FFFEHGE?CB@BF?FDDFBEHHGGGEEHGGG<@C@=F7@)@=CEEEEFACCBDCCECEA5>CCCCCC
@6DA
CCAGCCCCCGGCAGGAGAGCACACGCGTGATCCGGCTGATGCCCAGCCCCATCATGCACCCTCTGATCCTGAACCCCCGGCACTCCGTGGATTTCAAAC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJHIIJJJ;BBEFFFFFEEEDEDDDDDDDDDDDDDDDDDDDEDDDDDDDDDDDDDDDDDDDDBDDBDDDDEDDD
@6DB
GCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGT
+
CCCFFFFFHHHHHJJJGHJJJIJJIHIIJJIJJIJIJIJJIJJJJJJIJJJJJJJJJJJJJJJJJJJIHHHFFDEDEEDDDDDDDDDDCDDDDDDDDDDD@
@6DC
GCTAGAAGACCTTGGTGATTTAAGGCGGCAGGTTAAACTCTTAGAAGAGAAGAATACCATGTATATGCAGAATACTGTCAGT
+
C@CFFFFFHFGHHIGHGIIJJJEGGGHGJIGIBFHGHGJIJJJGJJCHIJIBHEHFACBCCCFDFCDEDDDEDDCCC@@AAA
@6DD
TGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGG
+
@BCFFFFFGHHGHJJJJJIIIJIJJJJJJJJJJJJJIJJJJJJJJIJJAGHIJJHHHHFFFDDEDEDDDDDDCDDDDDDDD@CDDEDDDDDCDEDDDDDDD
@6DE
GAAACCTCAAGCTGAGAAAGTTGATGTGATTGCCGGCTCCTCCAAGATGAAGGGCTTCTCGTCCTCAGAGTCGGAGAGCTCCAGTGAGTCCAGCTCCTCTG
+
CCCFFFFFGHHHHJJJJJJIHHGHJJIIJJIJJJJJJJJJIJJJJJIJJJJJJJJJJJJJJJHHHFFFFFEDDDDD=BBDDDDDCDDDDDDDDDDDDDDCC
@6DF
CCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCT
+
CCCFFFFFHHHHHJJIJJJHJJJJJJJGIJJJJJIJJJJJJIHIJJJJHHHHHFFFFFFEEDEEEDDDDDDDDDDDDDDEDDDDDDDDDDDDDDDDDDDDD
@6DG
AGTTAATGAAGATCAGATAAAGTTAATGAATGTGGCAATAAATGAACTGAATATAAAATTGCAAGATACTAACTCTCAAAAGGAAAAACTCAAGGAAGAAC
+
@<=DADDDAHHDF<AEGD@ADFII<DHH@BEHGGI339F?CG<FBD9:DF94BG>?DFGEE:DGHEC4==FHD4@7CCCAH@?A?CEBB@?3@>CCC?25,
@6DH
GGCATGTCTAAATCTAGTAATTTATTAGAAGCTTATCCATCCCTATTACTTTTTTAAATGGCATTAGTTCTGTGTGCTATTGGTGTTTATTTGCATCCACC
+
@@@D7DDDHBDDHIIBBAEIDIIHIHGIIIIFCHECHGHIDGEHGEIIHIGHIIIHECGGGCHGHCGEGHG@)=.=DH@HBHF.;;?DCECEACACCCCCC
@6DI
CTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTAT
+
CCCFFFFFHGHHGJJJIIGIJJJJJJIJJGGIJJJJJJJJJ6@FGHCEGIIHEEHHHFFFFEEEEDEDDDDDDCDDDDDCCCDDDDDDDD@BBBBCDDDDD
@6DJ
TGAAGCTCGTTCATCGGGACTTGGCAGCCAGAAACATCCTGGTAGCTGAGGGGCGGAAGATGAAGATTTTCGGATTTCGGCTTGTCCCGAGATGGTTATG
+
@@?DDDBD<@ADFGGIIE@EGEE@?EF;CFBACDHDBBBDBB9BDCCFHHIIGEBB?BB<:@CA>@C@@CC>97?BC>C<9?B38:4>0&002>(4>>A>
@6DK
GGACAACAAACAGGGGGTCGTGGAGTGCTTCCTCAAGGGAAGGAGCCTTTAGCAGTGCCCTGGGAAGGCTCTTCAGGAGCCATGTGGGGAGATGACAGAGG
+
?<;D>D;DADDDD3?)81?8)::DBDD><99D=8BEACADC;A=C;ADD>@;?;76;(;AA>???>?(,:<>A>A3:>?<>AA::>45>(5&9>AAAAAA8
@6DL
GGGAGACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTT
+
???DBDDDDD>D?AECEEE7E<::CDD;@?DDDBCDACCED@C@A<:AD>@@>@??AAAADDAA>AAA>>AA?<<A>AAAA>???>???;>8<>AA>AAAA
@6DM
GGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATC
+
CC@FFDDFHHHHHJIIJJJIIJJIIJIJJIJIIIJJJJGIJJJJJJIHIIGHIJJJGIHIHHHHHFFFDEEEEDDDCDCDDDDDDCDDDDDCDDDDDDDDD
@6DN
ATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTG
+
CCCFFFFFHHHHHJJGHIIJJJJJHIJJJJIJJJJJJIJJJJJJJJJJHIIJHHHHHHFFFFFFDEDDCCDDDDDDBDDDDDDDDDDDDDDDDDDCCDDDD
@6DO
GGAAACAAGCCCACTGAGACTAGTCAACCTCAANCNNNNNNNGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGT
+
CCCFFFFFHHHHHJJJJJJJJJJJJIJJJJJJJ#1#######00?FHGHIJJJJHHGHFFFFEDDEDDDDDDDCDDDDCDCCDDEDCDDEDDEDDDDDDD@
@6DP
AGTATTTCTGCTGCAAGTACTTCTGATGTTCAAGATCGCCTGTCAGCTCTTGAGTCACGAGTTCAGCAACAAGAAGATGAAATCACTGTGCTAAAGGCGGC
+
@@@DDB?DBBFHDBGBB<4C?AHHFHHCCFHH>FHEHDHACCBBB?B>GHGDDD?DFHGE@7;@F>FGDGEE>AHCHHD?>DCECC@>CCCCCC>@>@@BB
@6DQ
CTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTT
+
CCCFFFFFHHHGHJJJJIIJJJJJJJIJJJJJJJJJIIJIJJJIJJJJJIJJJJJJJJJJJJJIJJJHHHHFFFFDEEEEEEDDDDDDDDDDDDDDDDDDE
@6DR
ATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCA
+
@@@DDDDDBHH?A;EFH:DEFHGIIEGIIIIICCDAGDEFFCGIIEGHGIIDHHIIIEG;FHGIGFFH?BACCBCA;ACC@CB@C??B:ACACDC>@:AC
@6DS
TACACCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATGACATCTCCTGTGACTCTCACCTCTCAGACAACTAAGACAGATGACCCCCAATTGAAAAG
+
@C@FFFFFHHHHGJJJJJJEHHHHIIJIJIIGJIIHIEHGFGHHJJJIIGJIDHFDHGGIJJIGGGGEHHHJIIEF>CAC;@@E@CADDDBCDC@ACCC
@6DT
CAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHHHHFFFFDEDDDDDDDCDDDEDEDDDDDDDDDDDDDDDD
@6DU
AGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJHHHHHHFFFFFFEEEEEEEDDDDDDDDDDDDDDDDDD
@6DV
CTTGCAGCCAATTTACTGGAGCAGGGATGACGTAGCCCAGTGGCTCAAGTGGGCTGAAAATGAGTTTTCTTTAAGGCCAATTGACAGCAACACGTTTGAA
+
CC@FFFFFHHHHHJIIJJJJIIJIJIJJIIJIIIIJJJIIGHIHIIJJJIIJIJIIJIJJGIIIAEHHHHFFFFFFDDDDEDDDDDDDDDDDDD?ACBDD
@6DW
TATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTAC
+
CCCFFFFFHHHHHJJJJJIJJJJJJJJJJJJFHJJJJJJHJJJJJJJJJJJJJJJJJJIJJJJJIJJIHHHHHFFFFFEEEDDDDDDDDDDCDDEEDDDDD
@6DX
CTATGATAAACTTAGCCGTTCACTCCGCTATTACTATGAGAAAGGAATTATGCAAAAGGTGAGCAGCTAATACAGCATTAAAATTCATTGAAATGTTGCAC
+
CCCFFFFFHHHHHJJIIIJJGIJJJJJJIJJJJJJJJJHHFGGJJIJJJIHJJJJJIJJ@FHIIJJJGFHHHGHFFFFFFEEEEEEDEFDDDDDDBCCDDD
@6DY
CTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCT
+
CCCFFFFFGHHHHIJJJJJJJJJJJJJJIIJJJJJIJJIIJJJJJJJJJIJJJJIIJIGIJIJIIIJHHGHHFFACDDCDEEEDDDDEDCDCDDDDDDDDC
@6DZ
GGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACAC
+
@CCFFFFFHHHHHJJJJJI33CHIJJJJGIJJJJJJIIJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJGHHHHFFFFFDDEEDDDDDDDDDEECDDDDDD
@6E0
CAGAACTCATGGAAAAACTTGAGGTAACCAAGCGAGAGAAATTAGAGCTGTCACAGAGACTGTCTGATCTTTCTGAACAATTGAAACAGAAACATGGTG
+
CCCFFFFFHHHHHJJJJJJJJIJJJJJJJJJJIIHGGIHIJJJJJJIJJJJJJIIIHGJGIJJJJJJHHHHHHHFFFEFFEECEEECDCDDDDDDDD>C
@6E1
CTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTAT
+
CCCFFFFFGGHHHJJJHIJJJJJJJJJJJJJJIIIJJJJJJHIJIIIIJJJHEEHHHFFFFFFEEEEDDDDDDDDDDDFDDDDDDDDDDDDDDDDDDDDDD
@6E2
GAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGAC
+
CCCFFFFFHHHHHIJIJJJJJJJJIJIIJJJJIJJJJJJJJJJJJJIJJJIGFHHHFFFFEE@CCEDDDDDDDDDDDDDDDDDBDDDDDDDDDDDEDDDDD
@6E3
ATTAACTGGAGGAGGGAAAGACAGAAAAATAATTCTGTGGGATCATGATCTGAATCCTGAAAGAGAAATAGAGGTTCCTGATCAGTATGGCACAATCAG
+
?@@FDFFFF?DFBEHIIIIH@FHIGIIE?DBHGHCHGHFCEDHI@GEDEGGHGGFEGHGIIHD@GDHEFHE@DFBDCCEEC@CDC5>BC?BCACBCCCC
@6E4
CGAGCGCTCAGGATGGAGGAAGACTCGATCCGCCTGCCTGCGCACCTGCGCTTGCAGCCAATTTACTGGAGCAGGGATGACGTAGCCCAGTGGCTCAAGTG
+
??@DDFDDFHHGHIEG@EGDBGHGHIIIFHGIIIIIICGGI>FAFHIIHEFFFDDEECBBCC@A>@A@@C?C9ABD<?@D:?@BBBDDDDAC>?BC@AD4>
@6E5
AGGATACCTGTCTCCAGATCTCAGTAAGGTACGGAGTAACTGTCCAAAAGCCATGAAGAGATTAATGGCAGAGTGCCTCAAAAAGAAAAGAGATGAGAGAC
+
@?@DDEFFDFHDHIGDEGHGHGIIFHIIBFGHBHHGIHGIIHHHIGHGIECEGHEHIGIIGHGGGHIIHIGCC?CCEBDCEFED@ABDD>?=?CCDCCDBC
@6E6
CTCCCATGGAGAATAATCACTGCCCAGCGTCCTCCGAGTCCCACCCGAAGCCATCCAGCCCCCGGCAGGAGAGCACACGCGTGATCCAGCTGATGCCCAGC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJIJJJJJJJIJFHJJJJJJJJJIJJJJHHHHFFFFDDDDDDDDDDDDDDDDDDD>BDDEDDDDDDDDDDDDDDD
@6E7
CAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGAC
+
@@@DDDFDFHHHHFJIGIFGGIEGIIIJGIHJGIEHGGGIGIIFHIIEHIIDHIGJ>FDEHEGGHGGGHHHFBB@CDCACDDDDCDDDDDDDDCCDDDDDD
@6E8
CCTCTACAACCCCACGTCAGAGTGTGGGATTCTGTTACTCTATCCACACTGCAGATTATTGGACTTGGCACTTTTGAGCGTGGAGTAGGATGCCTGGATTT
+
CCCFFFFFHHHHHJJJJJJJIIFGEGIJHJJJJJIJJJJJJIJJJJJJJJJJJJJJJJJJJJIJJJJHHHHHFFFFDDEC;@D@BCDDDDDCDDDDDBDDD
@6E9
GTTTCTTCTTCAGGAAAACGGGCAAGAGAAGTGCATGGTGGGCAGGAGCAAGCCCTAGATAGCCCCAGAGGGATGCACAGGGATGGGAACACTCTGCCATC
+
CCCFFFFFHHHHGJJJJJJJJJJJJJJJJJJ?GHJJJJHHJJJJJIIJJJJJJJJJHHHHHHFFFFDDDDDDDDDDDDDDDDBCDDDDDDDDDDDDDDDDD
@6EA
GGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATAC
+
CCCFFFFFHHHHHJJJJJJJJJJJJIJJIJJJJJJJJJJJJJJJJJJJJJJJJIIJJJJJJHHFFFFEEEEEEEDDDDDDDDDBDDDDDDCDDDDCCDDED
@6EB
AGTACAGGGACTTCAGACATTAACCATGACAAATTCAGGCAGTACTCAGCAAGGTACAACTATTCTTCAGTATGCACAGACCTCTGATGGACAGCAGATAC
+
CCCFFFFFHHGHHJJJJJJIJJJJJJJJJJJJJJJIIJIJIJEHJJJJJJJJJJBHHIJ).=FHIJJJJIDHIJIJIHHHHFFFFFFEEDDEEDBDDDDDD
@6EC
CACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATG
+
CCCFFFFFHHHHHJJJJJJJGIJJIIIJJJJIJJJJJJJJJJJJJJJJGIJJJJJJJJHHFFDDEDDDDDDDDDDDDDDDDEDDDDDDDDDDDDDDDDDDE
@6ED
CACCACCTCGCCCGAGCCAGCCATCCTCCCTGGTCATCCTGGTGCGTCTGCACGCGGCTGCGGGAATTGCCAGAGGCTGTTCAATTTTGGAGGAAAACCTC
+
0((((:@(8-(:(<(((1)@=?()0(:)6())(0)9=.<)/)..)'--=(=1)-''3'''(,&&&0:(2:((++88<6(2((((((++(&(+((+8((+(5
@6EE
CGCTATCTGGTGTGGTCCCCACTGTCTACGAGGTGCATCCGGCTCAGTACTACCCGTCCCCCGTGCCCCAGTACGCCCCGAGGGTCCTGACGCAGGCTTCC
+
@@@FFFFFDHHHHIJ>FHGIJIIJHEIGHIIIF?DFHIJJIEIIIGIIIJIGHGGE;CHHFFDAB?AA@BDCDDBDDBDB-<<B0?ACDCC9B<BDB<CCC
@6EF
TCTTGAGTCACGAGTTCAGCAACAAGAAGATGAAATCACTGTGCTAAAGGCGGCTTTGGCTGATGTTTTGAGGCGTCTTGCAATCTCTGAAGATCATGTGG
+
C@CFFFFEFHHHHIHHIJJJJJJJIIJJJIJJJJJJJJJJJJJJJJJJJJJJJIGHGDDDDDBEDDCEDDDDDBDDDDDDCCCDCCCDDDDDDDDDDDDDD
@6EG
GGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATAC
+
@@@DDDDDDHHFH<EE?FHIGHCHGIHIIIIIGIHIIIIIIGEGIIIFIGGEHGEBFIIGIHHEBDDADCCCCCCCCCCCCCC<<?CCBBCBBC@CCCCEC
@6EH
AGAGGACAAGTGCAAGCCTATGTCCTATGAGGAGAAGCGGCAGCTCAGCTTGGACATCAACAAGCTCCCCGGCGAGAAGCTGGGCCGCGTGGTGCACATC
+
CC@FFFFFHGHHHJJJJJJJJJIJJJJJJIJJJIJJJJIJJJJJJJJJJJJJJJJJJJHHHGHFFFFEDDDDDDDDDDDDDDDDDDDBB<BD?BDDDDDD
@6EI
AGAGATTTTGCATATGACTCAGAAGTGCCTAGCTGCCACTCCATTTATATGAGGCAAGAAGGCTTCCTGGCTCATCCCAGCAGAACAGAAGGCTGTATGTT
+
C@CFFFFFHHHHHJJJJJIJJJIIJIEEJIIIGGIJGIJIIGHIIJJJHIHIIDHIJIGIIIIIIGIIIJEIIIJHHHHHFFFFFEECEEDDDDD?CDDDE
@6EJ
TGGGCCGCGTGGTGCACATCATCCAGTCACGGGAGCCCTCCCTGAAGAATTCCAACCCCGACGAGATTGAAATCGACTTTGAGACCCTGAAGCCGTCCAC
+
CCCFFFFFHHHHHIJJJJJJJJJJJJIHIJIIIJIIJJIJJJHHHHHHFFFFFFEEDDDDDDDDDBDDDDDDDDDDDDDDDDBDDDDDDDDDDDDDDDDD
@6EK
CAATCATTGAAGAATTAAACACAAAAATAATAGAAGAAGAAAAGAAAACTCTTGAGCTAAAGGATAAATTAACAACTGCTGATAAATTACTAGGAGAATT
+
CCCFFFFFHHHHFIJJJJJIJJJJIIIIJJJJJEIJJJIJJJJJJJJJJIJJJIJJIGIJIJIJJJJJJIJJJJHHHHHFFFFFFDDCEEEECDDDDDCD
@6EL
TTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGC
+
?@?ADBDDFDDF>FEIIHEGFICGHGGIIIEAFH@FHD9FFHGGHG<FGAE>9@CHGEEIAAEEECHFD@DEEDC>ACCC@B5?ACC9A>A@A??C9B<?A
@6EM
CACAGCCGGAGGTCATACTGCATCAGAACCATGAAGAAGATAACTGTGTCCAGAGGACCCCCAGGCCATCCGTGGATAATGTGCACCATAACCCTCCCACC
+
@<?A;8?88@CC+<??+<?<EG>4DF<F;DGFI<9B99B9DDBDF<9BFAB<FE9@2@6C=<<BDDC?>3;;,,2<:@AB3,55,,(24>B3:2(28<9<<
@6EN
CAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGC
+
CCCFFFFFHHHHHJJJJJJJJJJJJIJCGHIIJJJJJJBFHJJJJJIJJJJJJJJJJJJJJJIJIIHHHHHFFFFDDDDDDDDDDDDDDEDDDDDDDDDDD
@6EO
CGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCG
+
CCCFFFFFHHHHHIJIHHHJGHIFHGIIJIJJJJJJJJIJIJJJJHHGFFFFEEEEEEEDDDECDDDDDDDDCDDDDDDDDDDDDDDDDDCDDEDDDDDDD
@6EP
CAAACGTGCAGCTATGAACAGCAGAGTGGCTATGGTCAACAAAGCAGCTTTGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCC
+
7(3(-0(2:>;))))2):)9);>1<32):@:6)21)))):=96)9371.)9:1=19'(((.;::3=?9():9)6.=98/;;<5,(,:;522;7::::/:6
@6EQ
ATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHHHFDFFFFEEEEEDDDDDDDDDDDDDDDDDDDDDDDEDDDDDDDDDD
@6ER
CAAGGAAGAACTAGGACTAATTTTAGAAGAAAAGTGTGCTCTACAGAGACAGCTTGAAGACCTTGTTGAAGAATTGAGCTTTTCAAGGGAACAGATTC
+
CCCFFFFFGHHHHIJJJJJJJJJJIJIJJJJJJJ?GHGIJJJJJJJJIIJJJJJJJJJJJJJJJJJIJJIJJJJHGHHHHFFFFFFEEDDDDDDDDDD
@6ES
CTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATG
+
@@@DDDD?<FBAFGGACF<<CHHIDEHBF@DHBFEGGGIGEGIEIIE>EGGH@ECE:A?BBDBC;@C>CC;ACDCCCB?BB>>ACCC?B8()24:??BB?C
@6ET
CTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTT
+
CCCFFFFFHGHHHJJJJJJJIJJJJJJJJIJJJJJJJJJJIJJJJJJJIJJJJJJJJIJJJJIJGHFFDEEEEDDDDDDDDDDDCDCBDDCDDDCBDDDCC
@6EU
CCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATT
+
CCCFFFFFHHGHHJJIJJFHIJIJJJJJJJIJJJJJJJGGGIJJJIGIJJIJJJJIIJJJJJJIJJJJJHHHHFFFFFFEEEEEEDDDDDDCDDDDDDDDD
@6EV
CGATGCCAAGGGAAGGACGTCCTATGTACCAACGCCAGATGTCTGAGCCAAACATCCCCTTCCCACCACAAGGCTTTAAGCAGGAGTACCACGACCCAGTG
+
CCCFFFFFHHHHGJJJJIJIJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHHFFFFFDDDDDDDDDDDDDDDDDDDD3?CDDDDDDDDDDCC
@6EW
TTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGC
+
CCCFFFFFHHFFHIJHIIIGHGIJJJIEGIJJJGIJGGIIJEHIJJGIJJJJJIJJIJJJIIJGHHEHFFFFFFEEEEDEDDD?CCCDDCDDDD@CDDDB@
@6EX
CTTTCGCTATCGATCTCCTCATTCAGGTGATGTGCTCTATGAACTCCTTCAGCATATTCTGAAGCAGAGGAAACCTCGGATTCTTTTTTCACCATTCTTCC
+
@@@DD?DAFHHFDGDBBGCG<FFECCA????F?FGEHGEG@GEGGIGGGEFBFGHGGDFHIEGEGGG>EH>DAEHFHEEEBB>@CCAC?CCCCCCCDDECC
@6EY
CTCATTCTAATGATCAAAGTCCACAAATTCGAGCATCACCTTCTCCCCAGCCCTCTTCACAACCTCTCCAAATACACAGACAAACTCCAGAAAGCAAGAAT
+
CCCFFFFFHHHHHJJJJJJIJJJJJJJJIJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJIJJJHHHHHGFFFFFEEEEDDDDDDDDDCDDDDDDD
@6EZ
GTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCC
+
CBCFFFFFHHHHHIJHIJHIJJJJJJJJJJJJJJJJJIJJJJJJJIJJHHHHHHHFFEFFFEDDEDDDDDDBDDDDDDDDDDDDDCDDEDDDDDDDDDD
@6F0
CTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGC
+
CCCFFFDEHHHHHIJJJJJJJJJJJJJJJJHIIJJJJIJIJJGIJJJJJIJJJJJJIJJJJJHHHHHHFFFFEDDEEDDDDDDEDEECEDDDDDBDDDDD
@6F1
CCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTAT
+
CCCFFFDFFHFFFIJJIIJIJJJJJGGGHIIJJGIGIIJIJJJIGIGJJGIGHGFFDFEECDEECCCDCDDDDDDDDDBBDDBDDDDDDDDDDBDDCCCCC
@6F2
CTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJGIJJJJJJJJJJJJJJJHHHHFFFFFEEEEEDDEDDDDDDDDDDDDDDDDDDEDDDDDDDDDDDDDDD
@6F3
CCAAGATGAAGGGCTTCTCGTCCTCAGAGTCGGAGAGCTCCAGTGAGTCCAGCTCCTCTGACAGCGAAGACTCCGAAACAGGTCCTGCCTAATCATTGGAC
+
CCCFFFFFHHHHHIIJJJJJJJJJJJJJJHHJJJJJJJJJJJJIJJJJJJJJJJJJJJJIJHHHHFFDDDDDDDDDDDDDDDDDDDDDDDDDDDDDEDDDD
@6F4
CATGTCTGAGACTCCTGCTCAGTGTAGCATTAAGCAGGAACGAATTTCATATACACCTCCAGAGAGCCCAGTGCCGAGTTACGCTTCCTCGACGCCACTTC
+
?@@FDDDDHFDHHIIGEGBIIIIIHHIIIIIIIDIIIGGGGGIGGHIIIICHIIHIIIGGGGICADGEGCH??EHDDBABDD?DDDDCCDDDDBDDBDCCC
@6F5
AGCTGCAGCGCAGCAAGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATG
+
5-08@<48:--8--2).-.2@7;9)1.=<3..0=9--(-6>6-=53=3>;9>;:>8663=336673,,;32235;25;322:26686266<5::6;992:<
@6F6
CTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCC
+
;;:BDDDDFAF:<+<<@BEAFAGEFC4??D<:D?D?BGI9FB9(?FCDCF)@@@DFI@@EF;?A7;@?77@C(6;=>?B<<82>::+::<@B08?1:+4
@6F7
CCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTC
+
CC@DDDFFHAHHHIDIF@EAHGHIHII:E@EHGHIIEGIIIIICHGIIII@FHHIHDIGIIIGIIHCEDFFFDCEEEEDDDDCDDDCDDCDCDCDDBDDCD
@6F8
CACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGAT
+
:??DD;BBF=CFFCE<2@<8:?9?CFBFAFEDGGIF????BFB<B9?FBCFFA7@FIF@@@CE@CE9;;;@@CCC?3;=?>A>ABB>:8@B@???@A>>3:
@6F9
GACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGTTACAGTGCTTACAC
+
:::<AA=<0@=<<+<7CB=A8?)1:0?>A08=A/8>7)>=;/-':A35,'9=;;>?5((5;55595;5=5,,,;89?0;95;=;;5+8238;8::8;888?
@6FA
GTGCGAGAGCCTCCTCACTTGGATCCAGACATTTAATGTGGATGCACCATGCCAGACCGTGGAAGATTTAACGAATGGGGTTGTGATGGCCCAGGTTCTTC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJIGIJIJJJJJJJJJJJJJJJJJHHHHHHFFFFFFFDDDDDDDDBDD@DDEDDDDDDDDCDDDDD
@6FB
CACTTCCCTTGTGGGAATGTCAATTACGGCTACCAGCAACAGGGCTTGCCCTTAGAAGCCGCTACTGCCCCTGGAGCTGGTCATTACGAGGATACCATTCT
+
CCCFFFFFHHHHHJJHJJIHIJJJJJJIJJJJIJJJJJJIJJJIJJJIIJJJJJJIJJIJEHFFFEEEEDDDDDDDDDDDCDDDEEDDBDDDDDDDDDDEE
@6FC
CAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCAC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJGIIJJJJJJIJIJJJJJJJJJJJJJIJJJHIHHHHHHHDFFFFFDECEDDDDDDDDDDDDDDDDDDDDDDD
@6FD
TGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGG
+
@@@DDADEFFHHGGHGEEGBHGGHFHIJGGCFFEEFCCHCGHJGCEGE@ACGGD?EFHEFECDDDEDDDCDCCCC@CCBAC3>ACD<A@CDCCACDDDC<@
@6FE
CTTGCAATCTCTGAAGATCATGTGGCCTCAGTGAAAAAATCAGTCTCAAGTAAAGGCCAACCAAGCCCTCGAGCAGTTATTCCCATGTCCTGTATAACCA
+
@?@D?DDDFBDBHBBAGA@DHGAF>DDFGGGEHHIGHIIG>FD??BDBFI0BFHF?CDEG=@CHDHIFHE?D<9ACC>CDCC@@CCC@A;@C@@ADD>AA
@6FF
GCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCC
+
@@@FFABDFDDHD@EAHBHCAGGGGAHGIGC>DAHIC>EGCAHIIBEHA9AHCHGHGDDCE??C56;BEBCC@?;?;@C>;A@CCCCCCCC?9>A?@<@
@6FG
CAGATTTCGCCGCCAGCTTTCTGAACCCTGTAACTCCTTTCCTCCTTTGCCGACGATGCCAAGGGAAGGACGTCCTATGTACCAACGCCAGATGTCTGAGC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHFFFDEEEDDDDDDDDDDBDDDDDDDDEDDDDDDDDDDDDEDEDDDD
@6FH
CAGCTCACCTCCCTCCATCGCAGTCCATACCAGATAGCAGCTACCCCATGGACCACAGATTTCGCCGCCAGCTTTCTGAACCCTGTAACTCCTTTCCTCCT
+
@@@D?DDDHAAFFHIGIEGIIGC<CFBBGG@<GDEFDBB>@@GIIIICF=F<=BFGA=@CGH>@BA>A>;;BCCACCCC@CBB??>ADC>CCCCCCC>CCC
@6FI
GGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGC
+
(0(=?@??3:1.:8@5((<>==::>11<<9=<<>;)9>;6==19=<53/:)9=?=);=;;==>;7(33--:<;<;;:&52(2-88+6;:(2656:;<;<&)
@6FJ
CGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCA
+
@B@DFDFFHHHFHJGIJJJJIHGHIIHJIJJJJJJJGIGIIJIIIJJIIJJJEHJHHHHHFCDDDDDDDDDDDCDCCDEDDDDDDBDDDDBDDDDDDDD
@6FK
GCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGC
+
@@@FFDDDDDFFDIIBGHIIIGDHGGEHIIIIGEGIGIIIIIIEIGHHH@DHGIIIIIIGIBHEC@AEAEHFFFF>@C>C@@@CDCCBDDDDDDCCCDD?A
@6FL
CATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGG
+
CCCFFFFFHHHHHJJJIIJJJJIJIJJJJJJJJIGJJJJJJJIJGIJJJJIJJJIJJJJIJJJIJJJHHHHHFFFFCEEDECDDDDDDDDDDDDDDDDDC
@6FM
CCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGG
+
CCCFFFFFHDDHFCH@GHGGGGIBHGIAHG??EHIGGGHIIIIIIIIIIIIHIIIIGIIIGIIGDHD@D@DDEDEDE@@6>BDDDDDDDBBDBCDDDCCCB
@6FN
CGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTT
+
@@<DA?DDHH?FHIIFIGHBHBF@78CDHIICCHICHCHIGHEBDFIGHIHBFFHE=FBAHEHDB@DE;CC>A?B;A>ACCCC=B;>CACA9@3??@ACCC
@6FO
CAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJHJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJHHHHFDFFFFEEEEDDDDDDDDDDDDDDDDDDDDEDDD
@6FP
ATGAGAACACTGCATCTGCATTCATAGCCACGAGTTTGTTATTGCTACAGGCTACTGAGCGTCGTAACAGGAAAACCACCCACAGCTGACCGGCTCGGTGG
+
BC@FFDFFHHHHHJJGIIACIJHJIHGJIIGHJJGHIIHGIIIJIJJJJIJJHIIIJJJJIJGGEEHFFFFEEEEEDDDDDDBDDDDDCCDDBDDBBB8<@
@6FQ
TGTTGACCTTGATCGTCAGCTGAAGAAAACTACAGAGGAACTAAATGAAGCTTTGTCAGCAAAGGAAGAAATTGCTCAAAGATGCCATGAACTGGATATGC
+
CC@FFFEFGGHHGJIGIIJJIIGGIIIIJIIJIIEGIIGIHGGJIEGGEIIHIIGFGGIIIJGHGIIGGIIEEHECEDDDDB@CCCDCCCCCCCCCCDCCA
@6FR
ATTCTTCAGTATGCACAGACCTCTGATGGACAGCAGATACTTGTGCCCAGCAATCAGGTGGTCGTACAAACTGCATCAGGAGATATGCAAACATATC
+
CCCFFFDFHHHHGGIJJGIJIJGJIJJJJIIIIIJJJJJJJJJIJJJJJJJJJJJJJJBCHGGIIJGIGEFHHHFFFFFFCDBECDDDEDCDDCCDD
@6FS
GACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCC
+
CCCFFFDFHHHHHJJJIJJJJJJJJJJJJJ@FGIJJJJJJJIJJJIJHJJJIHHHHHHFFFFF>CECDEECDEDDEDDDDDDD:@CDCDDDBDBBCDDDD
@6FT
GGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTAC
+
CCCFFFFFHHHHHJJJIIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJHHHGGFFFFDD>BDDDDDDDDDA?CDDCDDDEEDDDDDDDDDDDDD
@6FU
GACCGAGTCGTCCATGTACAAGTACCCTTCTGACATCTCCTACATGCCTTCCTACCATGCCCACCAGCAGAAGGTGAACTTTGTCCCTCCCCATCCATCCT
+
@@CFFFDDHHCFHIIJHIHJIIFFGHIGIIIGGHIIGGIGHGIIJGGIHJIJEHJIJJJJIJIIJHFFGHFFFF7>@CEDEEDACDDDDDDDDCDDACCDC
@6FV
GGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATC
+
C@CFFDDDHHHHHJJJJJJIIGIJJJJJJJJIJJJIJJDGIIJIIJIHHIJJJJJIJJEHHHHHHFFFDEEEEDDDDDDDDDDDDCDDDDDCCDDDDDDDD
@6FW
CACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGAT
+
CCCFFFFFHHHHHJJIJJIJJJJJIJJJJJJJIJJIHHGIIJJJJDGGGIJJJEIGGJJJIIHGHHFFEDDDEEDDDDDDDDEEDDDDDDDDDDDDDDDDD
@6FX
AACACATGGCACAGATGGAGGAAATGAAAACACGGCATAAGGGAGAAATGGAGAATGCTTTAAGGTCATATTCAAATATTACAGTTAATGAAGATCAGAT
+
CCCFFFDDHHFADIIGGEHGIDHIIIIIIGIIIGIIHGGIIDH?HHGGHIIIIIHIIICHHHHHHACEFEFFB@DE>CEDDCCCDCDDCC>@>>C@CC@A
@6FY
CTTAGAAGAGAAGAATACCATGTATATGCAGAATACTGTCAGTCTAGAGGAAGAGGTAAGAAAGGCCAACGCAGCGCGAAGTCAACTTGAAACCTACA
+
;???:==2C;:+A?2<<<:<AC:<CAC?E@?<<A:C@F<EBGGIEGC<????B?B)099?8C;3=FF@=5@BAEBDC>>:88:>@BBBABBBB@AABA
@6FZ
GGCTTCTCGTCCTCAGAGTCGGAGAGCTCCAGTGAGTCCAGCTCCTCTGACAGCGAAGACTCCGAAACAGAGATGGCTCCGAAGTCAAAAAAGAAGGGGC
+
CCCFFFFFHHHHHIJJJJFHIJJJIJIIIJJJHJJJIJGGJJJJJJJJJJIIJIGJJHFHFFFFDDDDDDDDDDDDDDDDDDDDBDEDDDDDDDDCDDDD
@6G0
CTTACTACAAGCCAAACAACAGATCCTCACTCATCAACAGCAGCTTGAAGAACAAGACCACTTATTAGAAGATTATCAGAAAAAGAAAGAAGACTTCACA
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJIJJJJJJJIJJJJJJJIJJJJJIJJJJJJJJJJJJHHHHHHFFFFFFEEEDDDDDDDDDDDDDDDD
@6G1
CTGATTCTATAGAAGACCCTAACAGTCCAGCAGGAAGAAGGCATTTGCAGCTCCAGACTCAATTAGAACAGCTCCAAGAAGAAACATTCAGACTAGAAGC
+
@@CDFFFFHHFHFGGIEHJJIJEHGHGGIIIADGHIIHIJJJGJJIGGIJJIJDHDGGIJJIIIJGIIIHJJEFHHHFFFDFEEEDEDDEDDCCDDDDCD
@6G2
TGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTAC
+
@@@DFFDDHHHGGJJJIHIJIIJGCGIJII<DGGIIIIIGGHIGIJGFHIJGHGIIJJIJGEHEFEDDFDCEEEC;@CDDDCDBDDDDDBDDDCCDDDDD
@6G3
GCCCTTCCGACCAGCAGATGAAGATCATCGAAATCAATTTGGGCAACGAGACCGATCCTCATCAGCTCCCAATGTGCATATAAACACAATAGAACCTGTC
+
CC@FFFFFFDHHHIJJJCHGGIGIIGGHHIJJGEEDFHIIIJJJJIJGCBHAGGHFDDEEDCCCCCCACD?DDA>ACDEDDEEDCDDDBDCCDDDDD<AC
@6G4
GCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACT
+
+=1+?2@+++<227=<81<7<CB9AA==@?A3?*1??77?A=>ABBBBBA4A<>=B<AA=55=AAA<A;==3>@>((.;;3;;95,5(55(55;((59=?3
@6G5
TGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCC
+
@@@FBDAEHDDFFGEEFBGIGHHHGFHHD@BFGFGEGIEGFGEGGIIGHEHHFEHHFEEFFCECECACBBDDDB??BDBACCDDCDEDACCDDB@BBD?BD
@6G6
GCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGT
+
@@@DFFEDHGGGHGFHEBHGGGIIGHGGIGHDHDBFGIJIJJIIIGGIIHEEDGGEBFFGGGHIGEDEEHFFAB>?BCDDDDADDBBCDCBDDDD>A@CC4
@6G7
CCTGACCGGGCCTTCCCAGCTCACCTCCCTCCATCGCAGTCCATACCAGATAGCAGCTACCCCATGGACCACAGATTTCGCCGCCAGCTTTCTGAACCCTG
+
CCCFFFFFHHHHHJJJJJJGIIIJJIJJJJJJIJJJJJJIGHIGIJJJIIJJIJHHFHHFFFFDEEEDDDDDDDCDDDDCDDDDDDDDDDDDDDDDDDDDD
@6G8
GCTCAGACCACTGCAACCTATGGGCAGACCGCCNANNNNNNNTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCC
+
?<=DDBDDFHHHDB@FGEGE>CAGIEDFG=DGH#0#######--7@FEHG;@AGHFFHEEEECCA6;@AD@>AC@@C>CCA:AC?BBBB<@BBA@ACCCB
@6G9
GTTCGACTGATGACTCTGAGGAGGAGCGAGCCCAGCGGCTGGCTGAGCTCCAGGAGCAGCTCAAAGCCGTGCACGAGCAGCTTGCAGCCCTCTCTCAGCCC
+
CCCFFFFFGHHHHJJJJJJJJJJJJJIJJJJJJJJJJJJIJJJGHHHFFFFFEEDDDDDDDDDDDDDDDBDDDDDDBBDDDDDCBDDDDDCBDDDCCDDDD
@6GA
CTGCAGTTCAGAGGTAAATGGTTGCAGTTTTGTGATGAGAACAGGAAAGCCTACAAATTTATTAAGGGAAGAAGAATTTGGTGTTGATGATTCTTATTCTG
+
@C@DDDDDDDFHFGAE@EHEHFHAGHIIGHGGEEIGIIIIIGGHIIGGHCGICHIIIGGE@FHIIIII?EGHAHHHHHFFF?BABCEE@>;>>CCCCDACD
@6GB
AAACAGAAACATGGTGAGATTAGTTTTCTAAATGAAGAAGTTAAATCTTTAAAGCAAGAGAAAGAACAAGTTTCATTGAGATGTAGAGAGCTAGAAATCAT
+
@C@DFFFFHFHGDHHGGHJJJJIFCHGGIGEEHGIIIGCHGHIJGGGHGHGGHIJJI@GHHGIIGGEHHC@FH;==CDH<2=A)?;;?CD?CEACCCDDCC
@6GC
CAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTAC
+
CCCFFFFFHHHHHIGJIJJGIJIIIIJJJJJIIGIJJFHIJJJJJJJJJJJJIGGHIJHHF?BDDDDDDDDDDDDDDDDDDDCDDDDDDDDBCD:ACDEDC
@6GD
GGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTT
+
@@@BDFDDFAF?FHEEAH@DHIIG<EH?GHIIIFCGGIII:9?DGHGDGHHIGBCHGGA;CFGEHDGE?EEHDBCEEDEEC7?A?6;;?CCCECCCCCC>
@6GE
CCAACCCCGACGAGATTGAAATCGACTTTGAGACCCTGAAGCCGTCCACACTGCGTGAGCTGGAGCGCTATGTCACCTCCTGTTTGCGGAAGAAAAGGAA
+
@@@FDFFFGHHHGIGIIIJIJIJIIIIJGJIJJJJJJJDIIIIJJJHHHDFFFFDDDDBDDDDBDDDDDDDDDEEDDDDDDDDDDDDDDBBDDDDDDDDD
@6GF
TTCTTCAGTATGCACAGACCTCTGATGGACAGCAGATACTTGTGCCCAGCAATCAGGTGGTCGTACAAACTGCATCAGGAGATATGCAAACATATC
+
CC@FFFFFDFFHHGIJIIGIJIIIGIGGHIJIEGEHEGIFIGEGIJJGGGIJJGIIJ@FEBEHJGEHEHFEACECFEBDDC?@@C@CEDDDDDCDD
@6GG
ACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGC
+
CCCFFFFFHHHHHJJIJJJJHIIJIJJJJJJJJJJJJJJJJJJIJIJJJJJIJJJJJJJJJJJJJHHHHFFFFFDEEEEEEDDDDDDDCDCCDDDDDDDD
@6GH
GATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCC
+
CCCFFFFFHGHHHJJJIJJJIJJJJJJIIJJIHIIJJJJJJJIJJIJJJJJJJIJJJJJJGFHHHHHFFFF>@DECEDEDDDDDDDDDDDDDDDDBDDDDD
@6GI
CACAAGGCTTTAAGCAGGAGTACCACGACCCAGTGTATGAACACAACACCATGGTTGGCAGTGCGGCCAGCCAAAGCTTTCCCCCTCCTCTGATGATTAA
+
CCCFFFFFHHGHFGIJIJJJHHJJJIJJJJIJJDHFIGHGIJJJJJIIJJIJJJFGIIHHHEHFFDDBDDDDDDDDDDDDDDDDDBDDCDCDDEDDEEED
@6GJ
CAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAAC
+
CCCFFFFFHHHHHJIJJJJJJJJJJJIJJJJJIJJIJJJGGJGJIJIJJIGIJJJIJJIIIJJJHHHHHFECEFFCEEDEEEDDDDBDDDDDDCDDDDDDD
@6GK
ATAAGTTTCGGGGTGGACGAGGCGGGTGGGCGAGAAGCAGCGAAAGGGCATTGCACAAAAGGGGGGAGCCGCGGGGGGGGGGGGGGGGGGGGGGAAAAGGG
+
(00-:))).2(0((((1)((((((-5',''(',&&&(((+(0&)&0/((((((((++((+(((&)0&&&(&&)&))595&0&&)05&&&&&)&&&&((((+
@6GL
CACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAAT
+
CCCFFFFFHHHHHJIGIJJJJJJJIIGIHIJJJJIJJJIIJIIJIJIJJJIJJIJJIJJJIHHFFDEEDEDDCDDDDDDDDDDDDDDCDDCDDDCDDDDDD
@6GM
CAGGAACCCAGAGATTTTGCATATGACTCAGAAGTGCCTAGCTGCCACTCCATTTATATGAGGCAAGAAGGCTTCCTGGCTCATCCCAGCAGAACAGAAGG
+
CCCFFFFFHHHHHJJJJJJJJJJJIJJJJJJJJJGHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHHGFFFFFEEEEDDDDDDDDDDDDDDD
@6GN
CAGATTTCGCCGCCAGCTTTCTGAACCCTGTAACTCCTTTCCTCCTTTGCCGACGATGCCAAGGGAAGGACGTCCTATGTACCAACGCCAGATGTCTGAGC
+
@CCFFFFFHHHAHHJJJJJJIJIGIIJJGIIJIJIJJJJJJJGIIGJIIJIJIIHEDFDEEEDDBABDD@BDBDDDDCDDDEDCCBBDDDBBCC@CDDDCD
@6GO
CAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTAC
+
;?<DDABAAC8FDDFD<9CD>GGIICEHHGIDGG;DHGH?GGGGH@FI17@EGCHEHEC?BDEAACCCCCCCCC@;CA?>CCCCCCC@CC><?@755<>BC
@6GP
CTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGC
+
@@@FBDFFHHFHDHB@GFFHIGEIIGIEE>?GGEBHGGHIGGIGECEGIIIIGEGGGIGAFHA>=ECCCE?EE@DFD@AACBDDDBD@BDDDCDDDDDDDD
@6GQ
ATGAGATACTGCCCACCACCCCCATCTCAGAACAGAAGGGTGGGAAGCCAGAGCCGCCTGCCATGCCCCAGCCAGTCCCCACAGCATAACAGGGTCTCCTT
+
<@@FDFDFFHFGHI@GH3C=AFHC@DHHG@>FC3DD@GGI)BFEGGG26@GBGCCE>D<A6;>;>A@AB1<A?BB(5@CB?>0889>>4::@BB333>AC:
@6GR
GCGTAAGGCCAAAGCTGCAGCCATCAACACTAGCCGAGTTTTAACTCAGGAAGACTTTCAGAAAATCCGCAGGGCCCAAATGAGAAAAGAACTTGATACTG
+
=;14=+A:C+C?+222+<C++3+<C++1C):9*):?:?8)*9DF*/?4C))..=.)84)7@EEFEF))5;,'',((,8@B3(,55>A<9<?@A@:44(+((
@6GS
CCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGT
+
CCCFDFFFFHHHFHGEEGBGGIIFHIHIHHIIIDEGIEGGGFCH=CFGHGDGF?AAECC?@D>CCACECDC==;ACCDCBDA@@BD>???8<CDCDCBB8:
@6GT
ATTTATATGAGGCAAGAAGGCTTCCTGGCTCATCCCAGCAGAACAGAAGGCTGTATGTTTGAAAAGGGCCCCAGGCAGTTTTATGATGACACCTGTGTTGT
+
@CCFFFFEHHGHHJJJIJGIJJJJJIGIIGIGIIJJJJJIIIJJJIJJEHJJJGEHIGIJIGIIGEIIHHHFFFDDCDCCEDDDDDEDECDDDDDDDDCD<
@6GU
CCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJHHHHHHFFFFFEEEDEDDDDDDDDDDDDDDDDDD
@6GV
CTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCT
+
CCCFFFFFHHHHHJJJJJJJJJJJIIIJJJIJJJJJJJJJJIJJJJJJJJJJJIJJJJJJJJJJJJJHHHHHFFDDDDDDEEEDDEDEDDDDDDDDDDDDD
@6GW
GCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGC
+
CCCFFFFFHHHHHEHIJJJJJJJJGIJJJJJJIJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJHHHHFFFFFEEEEEEDDDDDDDDDDDDEDDDDDDDDD
@6GX
CCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGAC
+
@@@DDDDDFD?CBFFA8:?BG8?ED3CFFDFFII<;DFF?GEF?9?88?FDBDF>:.@F5@DCECEEE9?C;BDB?CBBBB?BBB>>@5;>AAA30<<@88
@6GY
AGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGC
+
CCCFFFFFHDHHGGIIJIIEHFGGGGGHIJIGIGBHEIGGCHGGGIDHGG@HIIIGEGDG@=AEHHFFD@DCDCEECDCCCDBDDD=@CBDDDACCBBD>
@6GZ
CCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGC
+
CCCFFFFFHHHHHJJJJJJJJJJHHIJIJJJJGIIJJJJJIJJJJJJJJJIJJJJJIIJJJJJIHHGHHHFFFFFDDDDDDDDDDDDDCDDDDDDDDDDDD
@6H0
TCCCACCAAGGTTGTGGCCCCGCCCTCATCCAGCGACAGCAGCAGCGATAGCTCCTCGGACAGTGACAGTTCGACTGATGACTCTGAGGAGGAGCGAGCCC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJHHHFFDDEEEDDDDDBDBDACDDDDDDDDDDDDDDDEDDDDDDDDDDDBDDDDDDDD
@6H1
CCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTTATGGGCAGGAGT
+
@@@DB??DDF>?<AFF@GA@:<BFGEC>FEFFBDGCBDG@D?@0@@B@;BFF@CDE@@A;E4:8;;26==CBB??5:AAAA@@B:<@B?4@A@??<9@8@@
@6H2
TGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCT
+
CCCFFFFFHDHHHJJJJJJJJJJJIJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHHHHFFFFFFECEEEDDDDDDDDDDDDDDDD
@6H3
CAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJIJJJJIJJJJJJJJJJJJJJJJHHHHHHFFFFEEDDDDDDDDDDDEDEDDDDDDDDDDDDDDDD
@6H4
CATGATGGCAGTGTGTTCACACTTTGTCAGATGAGAAATGGGATGTTATTAACTGGAGGAGGGAAAGACAGAAAAATAATTCTGTGGGATCATGATCTGA
+
CCCFFFFFHHHHHHIIIJJJJJJJJJHJJJJJJJJIJJJJJJIJIIIIJJJJJJJJDHIFIJJJJJJJHHHHFFFFFEEEFEEEDDDDBDDDDDDDDEDD
@6H5
CAGAAACATGGTGAGATTAGTTTTCTAAATGAAGAAGTTAAATCTTTAAAGCAAGAGAAAGAACAAGTTTCATTGAGATGTAGAGAGCTAGAAATCATTAT
+
CCCFFFFFHHHAFHIGIJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJIJIJJIIJJIJJIJJJJGIGGHEFHHHHFFFFEEEEEEDDEEE
@6H6
GCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTC
+
@CCFFFFFHGHHHJJJJJJJIIJJJJJJJJJJJHIGIIJIJIJICFHJIJJJJGHHHHHFFFFCECEEEDACDCDCDDBDDDDDBDDCDDCDDDDEDDDD
@6H7
CAAAACTTTTGTAGCAGAAACATTGGAAATGGGTGAGGTTGTTGAAAAGGATACAACAGAACTCATGGAAAAACTTGAGGTAACCAAGCGAGAGAAATT
+
B@CFFFFFHHHFHIIIJJJJJGIIJJAHHIJJJCGIJJDGGIJJGIJIGIJJIJJIJIGGIIIJIJJGIGHFHGFEFEFC@CEEEDDDDD@B@BDDDDD
@6H8
GGAAGAAGGGCAGCAGCAGGAGGAGGAAGGGATGTATCCAGATCCAGGTCTCCTGAGCTACATCAATGAGCTGTGTTCTCAGAAGGTCTTTGTCTCCAAGG
+
CCCFFFFFHHHHHJIJJJJJIJIIJIIJJJJHGIGIJJIIJJIJIJJJGGIIJJIHGGJJJHHHHHHFFFFFFACCEEEDEDDCDD>CDDDDDDDDDDDDD
@6H9
CTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGC
+
CC@FFFFDHFFHFGIJIJJJJIJJJGIJJJJFIJJJJJJJIGIJJIIEGHIJIJJGGIIJJCHGGEFGHFFFDDEEEECCEEDDDBDDBDDCCDBDDDDD
@6HA
GTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGAT
+
@@@DADD;DFD;2A:?<GAGBAFFHBBFG;CBDGDDFEFDB?DF4BBFI@FFIIDF@@@CDCFEFFC=A;BDDDD>BCCCBCBBBBBB=BB?>BB:AAAB:
@6HB
AAGAAAACAGGGAATTTTTGGGAAATATGAAAAGCCAAAATTTGTGCAGTGTTTAGCATTCTTGGGGAATGGAGATGTTCTTACTGGAGACTCAGGTGG
+
@@@FFFFDHHHHHIIJGGIGGIHHHIGIJJJJJJJIEGEHGIJJFGAFFBFHGGGIIIIIHHIGEIGEHHHFFBEFDDCCEECDDCCABCBDDDDD@CD
@6HC
CACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCC
+
CCCFFFFFHHHHGIGIJJJJJIIIIIJGGHGIJIJJIJJJIJJJJJGHGGIIIJIJJJJJIJIJJJGEHHHHHHFFFFFDEEEEDDDDDDDDDDDDDDDD
@6HD
AAAAAATCAGTCTCAAGTAAAGGCCAACCAAGCCCTCGAGCAGTTATTCCCATGTCCTGTATAACCAATGGAAGTGGTGCAAACAGAAAACCAAGTCATAC
+
CCCFFFFFHHHHGJJJJIJJJIIJIJJJJJJJJJJJJJJJIJJIJJJJJJJJJJJJJJJJIJHHHHHFFFFFFECEECBDDDDBDDDDDDDDDDDCDEEEC
@6HE
CGCATCCAACCCATGAACCACAGCTTCCGCCTACAGCTTTCAGCAACCGGCATGGCCTTACCTCCTTTCCCGAAGATTCCAAGGGAAGGCCGACCCATGT
+
-5;;((.))25(=7))):22-.(():):5??((73:8>?1))))0)(('''-'((6=)8..).6/(((((-'3'',7(5;,2(+2(+(((+)&00)8574
@6HF
CAGGCCTCCTATGCAGCTCAGTCTGCACATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGG
+
BC@DFFFFHHHGHJJJJJJJJJIIJJJ3CFHJJJIJJIJJJJJJIJJIJJJJJIJJJJIJJJIJJJJJHEFEFFFFEDDECEDCCDDDCCDDDDDDDBCDB
@6HG
CGCTCCAGGTCACCTATCACGACAAATCACCGGCCTTCTCCTGACCCCGAGCAGCGGCCCCTCCGGTCCCCCCTGGACAACATGATCCGCCGCCTCTCCCC
+
@@@DDDDFD<CB?EBHGGIGGGIGHCHGHIIIGGIIIGGIIGGGHGIGGGBEEFBBC@@BBCBBBB;@BBBBC@BB<ACBBBCCCCCCBBB<>@BBACCCC
@6HH
AAAATGTTGAATGTAACAGCACCTACACCTCAGCAGTTACAAGCCTTCAAAAATGAAGTAGGAGTACTCAGGAAAACACGACATGTGAATATCCTACTCTT
+
;?@D;A222=AD?AAAF@AA<CEEBA3FF9AC?E9?1:::??::6BB9DFBD;?/98B))==C;.888@FE@A@7A>EFDBC/3;5>AB;@DA>;@B@BB>
@6HI
CCAAATTAATACCAAAAGTTACCAAAACTGCAGACAAGCATAAAGATGACATCATCAACCAAGAAGGAGAATATATTAAAATGTTTATGCGCGGTCGGCC
+
?=8;:;D;DD4+2<2CABA::33AFE;FFC+C?4;CCB8CDDDIID*?**9D<?D<DE9=(=6.88;A2A27=77..=?3;7?7?A>A3(,3>8,39;.0
@6HJ
CTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCC
+
CCCFFFFFGHHHHIJJJJJJJJJIIJJIJIGIJJIJGIIJIIEDGIGHIIIJJJJEHIJHHHHGHFFFFFEEEEDDDDBBBDDDDDDDCDDDDDDDDDD
@6HK
CTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCC
+
=?@D=ADDCF?FBEGGIGIIGHDF@A8EDFHGEEDHF?DFAGCHII@HGCHEIEGHIEHCEEHD?BB;?C@CCCCCC?C;CCCB?BB<8<<?>AACCC8
@6HL
TACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCT
+
@@@DDD;D?FHAHD;FHIIDFGG>EGDH?@68?BDF??DFHD>BDB';;EHEHHABBBECCC@;;@@;@ACC<(<<?BBB?<@B?>:@:CB<9?8<A<>9A
@6HM
ATACAGCTTTCAGTCAGATGTATATGCATTTGGAATTGTTCTGTATGAATTGATGACTGGACAGTTACCTTATTCAAACATCAACAACAGGGACCAGATA
+
CCCFFFFFHHHHHIJJJJJJHJJJJJJJJJJJJJIJJJIJJIJGGHIJJJJJJIJJJJJJIJIJIJJJJJJIJJJJJJJIJJJJJHHHHFFFBDDDDDDD
@6HN
GCTATGGACAGCAGAGTAGCTATGGTCAACAAAGAAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGT
+
@?=A=BB4?B?=FFIBGF?:<FEE:<A9<CFIII*:C*?1*9??8)889D8?F88-B=FFA.@=ECD3?A=>BDB((;@5@55>;5:A@9?9@85@AAAA:
@6HO
CTTTTCTCTTGGATATATGCCATACCCCAGCAAAAGCAACCAGGAAGTTCTGGAGTTTGTCACCAGTGGAGGCCGGATGGACCCACCCAAGAACTGCCCTG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJIJJIJJJJJJJJJJJJJJJJIIJIIIJJJJJHIJJHHHHFDDDDDDDDDDDDDDDDDDDDDDDDDD
@6HP
CGCCCAAGTGACCAGGGAAGTGTGTGTGTGTCCATGTGTATGCGTGTCCGTCTGTCCGTCTAGTGTCTGGGTTTGGCCCAAGACTGGGCCGTAGTTACAAT
+
-(02-5?7.)4)2><88(6(69@)231;6.18.)...)...))(07-09=7(89;:)7;7;??8=))).6;=/=;=>?/,3;(3;;5;8(&))86<;(4(4
@6HQ
CTCAAGTCCTTCCTCCGAGAGACCCGCCCTCGCCCGAGCCAGCCCTCCTCCCTGGCCATGCTGGACCTTCTGCACGTGGCTCGGGACATTGCCTGTGGCTG
+
??@ADDBDDFFHHEHGGH@DGHIGDHGGFHADGIIGGFGAGHDHEFEFCECCCC?BBACACCACB99<CCCC:>A?A@<<BCBB@BBBCC@CCC<CCC@BB
@6HR
GGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJIJJJJIJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHHHFFFFFFEEDDDDDDDDDDDDEDDDDDDD
@6HS
CAGCAGTCTCTTGTAAATTCAAAGTCAGAAGAAATGACTCTTCAAATCAATGAACTTCAAAAAGAAATTGAAATACTCAGACAAGAAGAAAAAGAAAAGGG
+
CCCFFFDFHHHHHGHJJJJJJJJJHHJIIJIIJJJJIIIHIJJIJIJJJJJJIJJJIGIIJJJJJIJIJJJJJFIIJJIIHHHGEDDCFEEEEBDDDDDBD
@6HT
GTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACT
+
CCCFFFFFHHHHHJJJJJJJJHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHHFFFFEEDDEEDDEEDDDDDDDDDDDDDDD
@6HU
GACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACAC
+
@@CFFFFEHHHHGJJJJJJJJJJJJJJHHIJIJJJHJIJJJJJJJJIJJJJJJJJJJJJJJIJJJJJJHHHHHFFFFFDEEEDDDDDDDDEDDDDDDDD
@6HV
GAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGGCAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACT
+
:=@DBD4:CFDHFIFGIBGEEIIIGIIIIAGEGGEIIIBGB9D3BFGFHFHECFCE2=CDHFFFFH.??:;CAC3>@9=>CCACBB9=8?<?ACCBB?BA
@6HW
GCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCC
+
???DDDDDDDB:C3<C?DFFFEDIIIFEEEEIIDIIIIDDDD@DDAC9@AADDECEEECC@DDD;?@7?>@9@?A?>;AAEAAAAAAA>>:5>AA????
@6HX
ATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGT
+
@CCFFFFFHHFFDGGHHFIGIHIIIJIIJFIIIJJGGEGFHJGIJJIIGIIGIJHHHHGFFFFDDDD@ACCDDDDDDDDDDDCDDDDDDCDDDCDDDDDDB
@6HY
CACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHIIJJJJJJJJJIJHHHHHHFFFFFFEEDEEDDDDDDDDDDDDDDDDDDDDDDDDD
@6HZ
CATCCAGTCACGGGAGCCCTCCCTGAAGAATTCCAACCCCGACGAGATTGAAATCGACTTTGAGACCCTGAAGCCGTCCACACTGCGTGAGCTGGAGCGCT
+
CCCFFFFFHHHHHJJJIJJJJJJJJJJJIJJIGIJJJJJJJJIJJJHHHHFFFFFDEDDDDDDDDDDDDDDDDDDDDDDBCCDDDCDBBBDCDDDDDDDDD
@6I0
GGTTACCACAACCACCACCCCATGATACTCTTTCACCCACAGCACAAATCCTACCTCCATCGCTAACCCCACTAAAACACTCACCAAGACCTCAACCCCTG
+
++:A?AA?+==CC7CAC9=AACC3*:?A<A>*:==?A)08))09A)/=).).=)8>8=A>AAAAA@@><=@@=??3;;9=?99====,8;33:38(8)02(
@6I1
AGTAACTGTCCAAAAGCCATGAAGAGATTAATGGCAGAGTGCCTCAAAAAGAAAAGAGATGAGAGACCACTCTTTCCCCAAATTCTCGCCTCTATTGAGCT
+
@@@FFFFFHHHHHJIJJIIJJHIJJJIJJJJJJIJIIGGFGHIJJJJJJJIJJJJGEIIGEHGIGHIIJHHHHHFFFFFEDEEEDEDDDDDDDDDEDDDDD
@6I2
CTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTT
+
?@@;D4ADD>FHD@BF??A<?FG>C<CHFHF@>BEBC9CDGEDEHGHGIIIIIFGGG<E1=A=CCE>BDD7?B=>?B?BBB9?<:;?B>>>CCDCB?995?
@6I3
GGAAGAGAATAAAAAAAGCAAAGCCAAGGAACCTCCTCCTAAAAAGACGAAGAAAAATAATAGCAGCAACAGCAATGTGAGCAAGAAGGAGCCAGCGCCC
+
@C@DDFFFHHHHHIJJJIIJJIJJJJJJJIJIIIJJIIJJJJJIJJJJIIIHHHHFFFFFDEDEEEDDDBDDDDDDD>CDDDDDDDDCBBDDDDDDDDDD
@6I4
CAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAAC
+
C@CFFFFFHHHHGIJJIGHIIJJJJJJJJJIJJJJJJJJJIJJI@DHIIJJJJJJIDHGGGIJJHGHHDFEFDDFEECEEEEDDDDDDDDDDDDDDDDDDD
@6I5
CTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCC
+
CCCFFFFFHHHHHJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJGHIJJJJIJHHIIIIHHHHHFFFFFEEEEEDDDDDDDDDDCDDDDDEEDDDDDDD
@6I6
CCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGC
+
CCCFFFFFHHHHHJJJJJJJJJJHIIJJJJJJHIIJJJJJIJIJIJJJJJJJJJJIHIJJJJJIHHHHHHFFFFFDDDDDDDDDDDDDDDDDDDDDDDDDD
@6I7
CCTGGGCCATACAGACTGTGTGAAATGCCTTGCTATACATCCTGACAAAATTAGGATTGCAACTGGACAGATAGCTGGCGTGGATAAAGATGGAAGGCCTC
+
CCCFFFFFHHHHHJJJJJHHHHJJJIIGIJJJJJJJJJJJJJJJJJJJJIJJJJJHIJJIJJJJJJJGHJJGIHHHHHFFACDDDEDDDDDDDDDDDDDDD
@6I8
CTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTAT
+
=@@DDD;B;AFHD:<CEB?;@GC?<D?DG;GDGIGH@FHGG;;F38@;CHACAEECEC?@@:?;3>CB9??(>A@ACAC>(>5(,8+8@BBBB@?C2<<@4
@6I9
ATTTGGAATTGTTCTGTATGAATTGATGACTGGACAGTTACCTTATTCAAACATCAACAACAGGGACCAGATAATTTTTATGGTGGGACGAGGATACCTGT
+
CCCFFFFFHHHHHJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHHGHFFDFFDDDDBDDBCDDDDDD
@6IA
AATTTATTAAGGGAAGAAGAATTTGGTGTTGATGATTCTTATTCTGAACAAGGAGCACAAGACAGTCCGACTCATCTAGAGATGATGGAAAGTGAGTTGGC
+
?<@DDDFDFFFDBHIIIIIJJJIGAEGGEFGIIIBGHEHIGHIEEGGIGHGEHGIIJJIIGEDGECEHIJHHFEFCBCCCEAECDECC?ACB:>:>>CA@C
@6IB
CTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTT
+
@@@D?DBFHGFDBGHIBHGFHIE3CCEDAHGGB?CF>EGCHGGEGGIEG@HGID;A>GEGCHDHCHED@CB@C9=@?BD9?AB?;?BBADCA@C>AB39<B
@6IC
GTCGTACAAACTGCATCAGGAGATATGCAAACATATCAGATCCGAACTACACCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATGACATCTCCTGTGAC
+
@BCFFFFFHHHHHJJJJJJHIJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJHHHHFFFFFDEEACDDDEDDDDDDDDDDDDD
@6ID
GTATCAGATCCTGGGCCCGACCAGCAGTCGCCTAGCCAACCCTGGAAGCGGGCAGATCCAGCTGTGGCAATTCCTCCTGGAGCTGCTCTCCGACAGCGCC
+
CCCFFFFFHHHHHJJIJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJHHFDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDCDDDDDDDBDDDDD
@6IE
CCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTTATGGGCAGGAGT
+
B@BDDFFFHHGHHIJJJJGHIIJJJJJJJJJJJIJIIJJJJIIJJGIGIEIFHGHJJJJIIHHFFFEDDDDDDDDAACCDEDDD:<9?CCDDDDBDDDDB?
@6IF
CCGAACTACACCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATGACATCTCCTGTGACTCTCACCTCTCAGACAACTAAGACAGATGACCCCCAATTG
+
CCCFFFFFHHHHHJEHJJJJJJJJJJJJJJJIJJJJJJHIJGGIIJJJJJJJJIJJIIJJJJJJIJJIJJJJHHHHHFFFFFEEEEEEDDDDDDDDDDDD
@6IG
AGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJHIJJJJJJJJIJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJHHHHFFDDDDDDDDDDDDDDDDDCDCDDDDEDDD
@6IH
CTTCTATTTAGTCACGAAGAAGAGCTTTCCAAACTGAAGGAAGATTTAGAAATTGAACATCGAATAAATATTGAAAAACTTAAAGATAATTTAGGCATTC
+
>==AAA?2?4=<4@>8<1+3?7@BB<AC@B9A<?BAAB>>:?A=?=9?A>BAABAA>A=AB77=;;ABBBBBBA;=AA@;;>?@;>3>;(5;;?>?>???
@6II
CTGGGCCATACAGACTGTGTGAAATGCCTTGCTATACATCCTGACAAAATTAGGATTGCAACTGGACAGATAGCTGGCGTGGATAAAGATGGAAGGTCTCT
+
?@?;?DDDFDD<FCF?E?CCGHHE<FHHGAFAEEGEEBGCHI>GI@FDFGHHBG>>BAGHGIIGC3@FH77@DE7?EFE9><A;@CCC;>ACC@A<?CCC@
@6IJ
GCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTTATGGGCAGG
+
@@CFFFDFGFHFDCFHEGHIJIHGIJIIIGHGIJIIIJJGHHGIIGIIJJIHHHHIHIIJJGFHEFFDDDDDDDBBDDDCDDDDD>>5?CCCDDDBCDD
@6IK
CGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCC
+
CC@FFFFFHHHHHGJJIJJJJIJIIIGIIIIHIJJJJJIIGGIJJIIIHHHHHHFFFF@DEEEDCDDDDDDDDDDDDDDDDDDDDDCCDEDDCDDDDBDD
@6IL
CCGGCCTTCTCCTGACCCCGAGCAGCGGCCCCTCCGGTCCCCCCTGGACAACATGATCCGCCGCCTCTCCCCGGCTGAGAGAGCTCAGGGACCCAGGCCGC
+
@@@DDFFFFDFFDGHHDEFEHHIHEHGGIIIIGHHB@@GEHEFABDBDDDBBBDCCCCDDBDBBD;B@CDDDD>BBB@BCDD8<ACCDCA?BDDDA??BBD
@6IM
GTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACT
+
:1=DDDAD<D=C<<A?CEDAA?C?B@E?7E88C<DD8CDDDDEI>DBA9*9BCCEI<.78=9=@C>ADCD7?5?3;(6@>6>>>;;>;5>>:=>(5=20;9
@6IN
GGAAGGGGCGACAGTGCTTATAAACGAATACAAAGAGTTGGCTGAGCTGCGAGGTCTGGCAGCCGGCGTAGGCCTGGCTAATGCCTGCTATGCAATGCAT
+
-;((==58(:-8=()0>?13)<1<1(-7(-.7)76.)>18..)6=973=?;==/,,54,:;6</;6&08&08:(+2(2:;:<558::;:(8+(((+856:
@6IO
CTGGACAGTTACCTTATTCAAACATCAACAACAGGGACCAGATAATTTTTATGGTGGGACGAGGATACCTGTCTCCAGATCTCAGTAAGGTACGGAGTAAC
+
CCCFFFFFHHGGHJJJJJJJJJIJJJJJJJJIJIJJGIJJJJJJJJJJJIJJJIDGHJIJJIHHFFFFFECEDCDDDDDDDDDDDDDDDDCCCDDDD<CCC
@6IP
CAGCACGCCAGTGTCCCCACTGCATCATGCATCTCCAAACTCAACTCATACACCGAAACCTGACCGGGCCTTCCCAGCTCACCTCCCTCCATCGCAGTCC
+
CCCFFFBDHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJHHHHHFDDDDDDDDDDDDCDCDDDDDDDDDDDDDDDDDDD
@6IQ
CACATACCAACGGCGAGGATCACTTCAGCTCTGGCAGTTTTTGGTAGCTCTTCTGGATGACCCTTCAAATTCTCATTTTATTGCCTGGACTGGTCGAGGC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJIJJJJJHIJJJJJIHHHHHHHFFFFFFEEEEEDDDDDDDDDEDEEEEEEDDDDDDDDDDDDDCDDDDDD
@6IR
AGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGAC
+
B@@FFFFFHHHHHJJJJJJJJJHIJJJJJIJJJJJJJJJJJJJJJJJJJJIIJJJJJJJGIJIJJJJJHHHEFFFFFEDDDDDDDEEDDDDDDDDDDDDDD
@6IS
GGAGCCTTTCTGGGTTGGGGAGAGGAAAGGAAAGTGAAAAAAACCTGAGAACTTCCTGATCTCTCTCGCTGTGAGACATGTCTGAGACTCCTGCTCAGTGT
+
CCCFFFDDHHFHGFAAGGIJ@FFHGGHGHGDHIJ@FGIIGGIGIIJHHHHGHFFFFDFEDDECDCACBD@B;C@CDDCACACDDACDDCCDACCDD>94:4
@6IT
CCCCTTCCCACCACAAGGCTTTAAGCAGGAGTACCACGACCCAGTGTATGAACACAACACCATGGTTGGCAGTGCGGCCAGCCAAAGCTTTCCCCCTCCTC
+
@@@FFDFFHFGHDBGGGGCHGIGHHHIIIIIHHGIIJJJHIFIJIGBBEECGHCCEHHGHFAHFE?;A>AC@;@CBDDBDBB?BDCCCCDDCDDCDDDDC?
@6IU
TGGAAACCATAGAACCTGTCAACATACTAGATGTTAAAGATGACTGTGGCCTCCAACTAAGGGTCAGCGAGGACACCTGCCCACTGAATGTTCATTCTTAT
+
;=?ADD>BFCFADB?@CFAGHBFHIIBFHF<?B?CEGDEBCCCFDD?BG=GBB@@FFEGHIIG==FHGIA=BD;C;;C@ABBC?<CCCCAC:;AA>>CC@@
@6IV
CAAGGATTTCGGGGTGAAGGCGGATCAACCACAGGGTTGTCTGACACACCCCCTGCCTCATTACCTGGCTCACTAACTAACGTGAAAGCCTTACAGAAATC
+
;(;(((:)).@((((-(.2=.(-(93(..7--(..(..-=)=)))))),95,9';((,:(,(:5(((2(86((((+(+++(289652(+(+8(+8:;62+(
@6IW
CAAATTCTCACCAGTCCGTCTCCTTCAAAATCCATTCCAATTCCACAGCCCTTCCGACCAGCAGATGAAGATCATCGAAATCAATTTGGGCAACGAGACCG
+
CCCFFFFFHHHHHJJJJJHIJIIJJJJJIJJJJJJJJJJJJJIJJIIJJJIJJJJJJJJJJJJJHHHHHHFFFFFFEEEDDDDCCEDDDDDDDDDDDDDDD
@6IX
AAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTAC
+
CCCFFFFFHHGHGIEHIJIJIGIJJJIJJJHGIJJJJIJJJJJJIGIIJJJJJHHHHFFFFDEEEDDDDDDDDDDDDDACDDEDDDDEDDEDDDDCDBACD
@6IY
CACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGAT
+
CCCFFFFFHGHHFIJJJJJGIJJJJJFGHIIIGIGIHGGIIGIJIIHIGIJJJJJIJIEGHIHHHHFFFEEDEEDD?BDDCCDEDDD>BDBDDDDDCDDDD
@6IZ
CATATACACCTCCAGAGAGCCCAGTGCCGAGTTACGCTTCCTCGACGCCACTTCATGTTCCAGTGCCTCGAGCGCTCAGGATGGAGGAAGACTCGATCCGC
+
CCCFFFFFHHHHHJJJJJJJJJJJIJJJJJJIJJJIJJJJJJJJJJIJJHHHHFFFFFFFEEEEEEEDDDDDDDDDDDDDCDDDCDDDDDDDDDDDDDDDD
@6J0
GTTGTTTTGGCTGTGGAGTTTCACCCAACAGATGCAAATACCATAATTACATGCGGTAAATCTCATATTTTCTTCTGGACCTGGAGCGGCAATTCACTAAC
+
@C@DDFFDH>BHDEFGAHHFH?HEHGAHIEGDGGHIEGGIIIIIIIIIIIHHIGIIIBHGAGGGCHEHEECEHFF>BBBBEEC@B?A>@BBBCCCACCAC>
@6J1
CCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTAT
+
CCCFFFDFHHHFHJIJJJJJJJIGJIJJJIJJJJHHIJJJJJJJJJJJIJJHFHFFFFFEEEECDDDEDDDDDDDDDDDDDDDDDDEDDDDDDDDDDDDDD
@6J2
AAGGAATTATGCAAAAGGTGGCTGGAGAGAGATATGTCTACAAGTTTGTGTGTGATCCAGAAGCCCTTTTCTCCATGGCCTTTCCAGATAATCAGCGTCC
+
CCCFFFFFHGAHHIIGIGAFHHIIGIGGJJJIGGIIJIIIJJJJDGGC?FDGEHGIEIJGIHCGIIJJJHHHHHHDDFFFFEEEDEEDCCCCDDDDBBDD
@6J3
CGATCTCTCTCGCTGTGAGACATGTCTGAGACTCCTGCTCAGTGTAGCATTAAGCAGGAACGAATTTCATATACACCTCCAGAGAGCCCAGTGCCGAGTT
+
+1=ADDDBFBBADEHCGGFEGHGGIIIGEEHHGHAFIGGEFHHB?DAHIIIE@DDDGIEGE@EIIIGG@D=CEEACHEEEDCABCB@BB;=:AAC=BB08
@6J4
GTTTCGCCGGCAGTCTCGATGATAGTATTTCTGCTGCAAGTACTTCTGATGTTCAAGATCGCCTGTCAGCTCTTGAGTCACGAGTTCAGCAACAAGA
+
CCCFFFFFHHHHHJJJJJGIIJIJJGIJJJJJJJJJJJJJIJIJJJJJIJJJJJJJJJJJIHHHFFFFFFDEEEEEDCDDDDDDDDDEDDDDDDDDD
@6J5
CCTCAACCCCTGTTTTCCCCTGCCTTCCTTGCAGAGGCCATGGAGGACGAGGAGAGACAGAAGAAGCTGGAGGCCGGCAAAGCCAAGCTTGCCCAGTTTCG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJIJJIJJHHHHFFFFEEECEEDDDDDDDDDDDDDDDDDDDDDDDDDDDDDEED
@6J6
AAGAGGTGGCCCGACGTTGGGGCATTCAGAAAAACAGGCCAGCTATGAACTATGATAAACTTAGCCGTTCACTCCGCTATTACTATGAGAAAGGAATTATG
+
CCCFFFEFHHHHGJJJJJIJIJJIJJIJJJJJJJJJJJJJJJJJIJJJHHHHHHFFFFFFFEEEEDDDDDDDDDCDDDDDDEDDEDDCDDDDDDDDDDDED
@6J7
CAGCAATTACAGGCTAGTGAAACTCTGAGAAACAGCACTCATAGTAGCACAGCTGCAGACTTACTACAAGCCAAACAACAGATCCTCACTCATCAACAGC
+
CCCFFFFFHHHHHJJJJHIJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJIJJJJJJIJJJIJJJIIJIJJIHHEHFFFFFDEEDDEDDDDDDDDDCDD
@6J8
CGGCGAGGATCACTTCAGCTCTGGCAGTTTTTGGTAGCTCTTCTGGATGACCCTTCAAATTCTCATTTTATTGCCTGGACTGGTCGAGGCATGGAATTTA
+
@@@FFFFA@FFHHIIIEBGHIIECGGGCFGIIBHFIHIIIIICHGIGIIGAFAGHGGHCHHECH@DFFFFFFCEA@@C?AC?B@@8=@?5?CBBCCCCCC
@6J9
GGAATTTTTGGGAATATGAAAAGCCAAAATTTGTGCAGTGTTTAGCATTCTTGGGGAATGGAGATGTTCTTACTGGAGACTCAGGTGGAGTCATGCTTAT
+
?<?BBDDDF?<6+2<CGEIFEBEC@G3CEGEEECFE4?FEFD;FEDFFI4DC4B;0<;(8=32@EC7C=;CAEC>;;?9?>B@ACA@@?2;>:@A@BDAA
@6JA
AATGAGTCAAAAGATAGAAACCATGCAGTTTGAAAAGGACAATTTGATAACTAAGCAGAATCAATTAATTTTGGAAATTTCAAAGCTAAAAGATTTACAGC
+
@@@FFFBDFHHGHHIIIGIJJJJEIIJIBHHJBEHGGIGJJIJJJJIJJJJJIHIJIIJGGIIIGEGJJGIJJJJIEHHHHHEDFFFEEECECEDDDACDC
@6JB
TGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGC
+
@<@=DBDDBHDHBGIIGGGHG@FCEHIIIGDI<G9FDAGDG;8@FHGCCE6@CEEEE@D)?C?>AC6@@@A;>ACC:>CC>>CCC?A?BB55?CCCCC<A<
@6JC
TTTGAACTCAGGGTCACCACCAGCTATTGGACCTTACTATGAAAACCATGGATACCAACCGGAAAACCCCTATCCCGCACAGCCCACTGTGGTCCCCACTG
+
@@@FAEDEHHHHGIIGIBHEFHE=GDHHJJDHGGIGIHGGHIHIJHIIJIGGIJGIJIGHIJGGGF@BED?CECDDBDDDDCDBDBDAC:AC<CCDBDDDD
@6JD
GTAAATAAAAGTTTTGGTGAAGAATCAAAAATAATGGTGGAAGATAAAGTTTCTTTTGAAAATATGACTGTTGGAGAAGAAAGTAAGCAAGAACAGTTGAT
+
C@CFFA?DDHGADGHIBAFHGIIGFIICBDDHCHCHG?CGEEBCDBHIIDHI@FDGCHIGCHIIIDGGIHE=CC>@CHHDCFDFFBCCCEECCCCCCCC>C
@6JE
AAGGGAAAGTGGCATGGTGATGTGGCAGTGAAAATGTTGAATGTGACAGCACCTACACCTCAGCAGTTACAAGCCTTCAAAAATGAAGTAGGAGTACTC
+
CCCFFDFFHHFHHJJJICHGIIEHIDII@GHJJJFGFGGIJIJIIIJJIEGHHGIJIGIIJIIIIJAHIGHIGHHGHFFFFFFCDCEE@ACCCC=>:@C
@6JF
TCATGTTCCAGTGCCTCGAGCGCTCAGGATGGAGGAAGACTCGATCCGCCTGCCTGCGCACCTGCGCTTGCAGCCAATTTACTGGAGCAGGGATGACGT
+
;?@FDADFHFHCFIJJJJGIIJJGGIIIIIIJIIJJIIJJGGHGFHHIGDGIGIEHEGBDBDEDBDDDDBB@CCDDDDDDDCCCD9AA<ABD<<@DDD@
@6JG
CAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGG
+
CCCFFFFFHHHHHJJJJJJJIIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIIJIJJJJJHHHHFFFFEEEEDEDDDDDDDDDDDDDDDDDD
@6JH
CAAATTCTCATTTTATTGCCTGGACTGGTCGAGGCATGGAATTTAAACTGATTGAGCCTGAAGAGGTGGCCCGACGTTGGGGCATTCAGAAAAACAGGCC
+
CCCFFFFFHHHHHJJJJIJJJJJJJJJJHIJIJJJJJJJJJJJJJJJIJIJJJEIJJJJIIIGGJIEHGHFFDDDDDDBDDDDDDDDEDDDDDD>BDDDD
@6JI
AAACAGGCCAGCTATGAACTATGATAAACTTAGCCGTTCACTCCGCTATTACTATGAGAAAGGAATTATGCAAAAGGTGGCTGGAGAGAGATATGTCTAC
+
@@@FFFFFHFHHHJIJJJJJJGIGHIIJJJIJIIIJJJJGJJIIJJJIBHIIJJIGIJIJJGGIJGIGEFGHHHFFF@CCCDDDBDDDDBBDDDDDFEDA
@6JJ
CAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCT
+
@@@DAD@DF:FC<4:4:CECCH?C9CEHEDFFBGD@>FFCEE3B@A>BD388=FAAE;@'5=@?C)??;@:5=;5;=(5:AC>;:@:((:5:<?33>9(3
@6JK
CAAATCAAAGCTCATGATGGCAGTGTGTTCACACTTTGTCAGATGAGAAATGGGATGTTATTAACTGGAGGAGGGAAAGACAGAAAAATAATTCTGTGGG
+
BB@FFFFFHHHHHJJJJJJJJJJHJHHIJJJJJJJJJIIJJJJJJJJIJJJJJJJIJJJJJJJJJIIJEHICHHHFFFFEEEDEDDDDDDDEEEEEDDDD
@6JL
CTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJIJJHHHHHHFFFFDEDBDDDDDDDDDDDDDDDDDDDC
@6JM
CTCCTCACTTGGATCCAGACATTTAATGTGGATGCACCATGCCAGACCGTGGAAGATTTAACGAATGGGGTTGTGATGGCCCAGGTTCTTCAAAAGAT
+
?@@1DDADHGFA>FFDBHHEGHIIGEHHADHHEHGHIIIIGGGIIGIIIICGHGIGIGGHHFGGGCECHH?BC<B>C@>ACA@BB:>@@A>CCCCC?C
@6JN
CAGTTAATGGGGACAGTCGAAGAACTTCAGAAGAGAAATCATAAAGACAGCCAGTTCGAAACTGATATAGTACAACGAATGGAACAAGAAAC
+
BC@DFFFFHHHHHJJJJHGIJJJIJJJJJIHIJIJIIIIIJGIJIJJJJIJJJIIJIIIJJGIJGHGHHHCHFFFFDDDBCDDDDDDCDCDD
@6JO
GATATTGCACGACAGACTGCACAGGGCATGGATTACTTACACGCCAAGTCAATCATCCACAGAGACCTCAAGAGTAATAATATATTTCTTCATGAAGACCT
+
CCCFFFFFHHHHHJJJIJJJJJJJJJJJIJJIJJJJJJJIJJJJIJJJIJJJJJJJJJJJJHHHHFFFFFEECECEDEFDEEEEFFEDEDDEEDDDDDDDD
@6JP
GAAAAGGAAACCTCAAGCTGAGAAAGTTGATGTGATTGCCGGCTCCTCCAAGATGAAGGGCTTCTCGTCCTCAGAGTCGGAGAGCTCCAGTGAGTCCAGCT
+
CCCFFFFFHHHHHJJJJJJJIJJJJJHIJJJJHHJJJJJJIJJIIJJJJJJJJJJJJJJJJIHHHHFFFFDEEEDD>ABDBDBDDCDDDDCDDDDDDDDDD
@6JQ
TGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGC
+
CCCFFFFFHHHHHJJJJIIJJJJJIJJJIJJJJJJJJJIJJJIJJJJJJJJJIJJIJJJJJJIIIHHHHHHFFFFFFEDEDEDDDDDDDDDDDDDDDDDD
@6JR
GTATTTCCAGCCTTTGTAGCTTTCACTTCCACATCTACCAAGTGGGCGGAGTGGCCTTCTGTGGACGAATCAGATTCCTCTCCAGCACCGACTTTAAGAGG
+
@?@FDADFD?FDADGHBDHHACHGIIECCFGHIG@BFHECF?CGI;B0;5A1@;A=C7@E;7??C>9@6A?:::@@CECC3?AC:A?BBBBBBBC@C>:><
@6JS
AGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCG
+
?:?BDDDD?AFBDB<AGEHIGIIICBACHC@ECFEGFGIIEDFFFFFFAFF8BDF@C@FFEFIIIFEEFFCAEDDDDC;;@AB;@BABD@AAAAA?AB@B5
@6JT
CCGTTGACGAAAACCGATGCAGGACCTGTGAGTACACAGACATCGGCCGATGCATCATCTCCAATTCACGACAACCCACCTTAGTAGAAGAAAAAAGGGGC
+
-((2(-()((((068(((-8)=753=))).69)))0).<)09.735;'''',().6.6..6(-4((7(,((''&(+&++&+++(+(++(+((+325&(2&0
@6JU
CCATGCCAGACCGTGGAAGATTTAAAGAATGGGGTTGTGATGGCCCAGGTTCTTCAAAAGATAGATCCTGCATATTTTGCTGAAAATTGGCTAAACAGAAT
+
>==+<7<+<7AB?)+4A+772?ABB*@@BA?>A??48A<49**9A=A218.>>B;ABABA=;>;7;7>;)6>@>;>@>=(-;>??=;(,(,,:??>;=?78
@6JV
TGCTTCCTCAAGGGAAGGAGCCTTTAGCAGTGCCCTGGGAAGGCTCTTCAGGAGCCATGTGGGGAGATGACAGAGGTACCCCCATGGCTCAGAGTTATGAT
+
???BD?DDFFF:<2<CB:??F?FHHIFE@B1:FFB??D;8DBFE3BF>?89==D=;FD:FE>B<;/566>@A;35?-;>:ABB2559??BAAA>ADA3++:
@6JW
ACTAAATGAAGCTTTGTCAGCAAAGGAAGAAATTGCTCAAAGATGCCATGAACTGGATATGCAGGTTGCAGCATTGCAGGAAGAGAAAAGTAGTTTGTTGG
+
?@@DDDDDBFBAFGBFH@FDHHBGGCEGBEFCCG@??CFEH>FHIEEH9BDBFGE@FFEHHIIB9=FAFIGGAGHEA>AE=@D?@@>CA(-5>;>@@,<B?
@6JX
ATAGCCGCAGTGAGAGGCAAACGGGCCATCGGGGTTGCGGATTGGAGCTCCGGTGGGTTAAGGGGTGGAAGAGAGGAAGGGGCGCCCGGTGGGGTGCCTGG
+
-0(2(:(((-2)))).(-((((((((((0)((0--'-('-'',6((.((-('','7'&((+((2&))&(((((+((((++5&&&&&)0585&05)0(6((+
@6JY
GGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCAC
+
@CCFDFFFFFDFFFEGHIIIGIJIGGGIIGEGFBHIIJIIJICG@>DEFHCHIGJEIIJJHGHCHFBDDDBBACCCDD?AB??CB>CCCACDD&5>AD<CC
@6JZ
CAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCAC
+
CC@DD?DDDHHGHJIGIJJJGHGIGIJJIJJIIGGIJIIJJJIIJJIGIEIIIJJJIGGFFDFFEEEECECBBDDDDDDCCDDDDDDCCACACAC?BBD?B
@6K0
CGAGGATACCTGTCTCCAGATCTCAGTAAGGTACGGAGTAACTGTCCAAAAGCCATGAAGAGATTAATGGCAGAGTGCCTCAAAAAGAAAAGAGATGAG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJIJJJJFHIJJJJFHIJJJIJJJJJJJJJJJJHIJJJJJJJJIJJIHHHH;BDFFFEEEEDDDDDDDDDDDDDD
@6K1
TTTACAACAAGCAAGAAGAGAAAAGGATGAGACAATGAGAGAATTTTTAGAGTTGACAGAACAGAGTCAAAAATTACAGATTCAATTTCAGCAATTACAGG
+
C@@FFFFFHHHHGIGIIHEHGHIIIJGEHGIGGIIIIGIGIIIIIIIIIGHGDEGGGGGGGGGGEG@@EHFHFFGFBDDDDCCEEDDCCCCCCDCCCCDDD
@6K2
GAAAAAATCAGTCTCAAGTAAAGGCCAACCAAGCCCTCGAGCAGTTATTCCCATGTCCTGTATAACCAATGGAAGGGGTGCAAACAGAAAACCAAGTCAT
+
?1:A?+<3:CD<D<4ABEECBA<F;88?8EC?D??8DDDDDDDDCEA>>AEA@AD7==@A@?A?D;776)7@>;>18?8;8:A:(599>A?A<<8<:A>>
@6K3
AGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGT
+
@@@FFFFFHHFHFBHGGIIJJGGIJJIIFDGHGHEHIIIGHGGGIIIGDFEHGJIGJGEHHHFBDCDDDDDCCCDBDDDCDDDDDDDDD59C@CBCCDCB@
@6K4
AAGCTGGGCCGCGTGGTGCACATCATCCAGTCACGGGAGCCCTCCCTGAAGAATTCCAACCCCGACGAGATTGAAATCGACTTTGAGACCCTGAAGCCGTC
+
<?@DDDDDH?HH?<ED?:9::DB?BHGDH@GC>@FH<54@;;7=;;;??@@;>>;C@BC>B;;2==53508@CCC:C3<()224>>8+:2?<C9A>C@BB9
@6K5
CCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGG
+
@@<DDDA?BFFFBGDHDGHHGGH=?FH<CGH9CB>DBFGDFDG16?3DB<DGGEE9.=AF8;@B=?BDFB?7;;;>D('9;@B9999<?@<??+:>:A@AB
@6K6
AGTACCACGACCCAGTGTATGAACACAACACCATGGTTGGCAGTGCGGCCAGCCAAAGCTTTCCCCCTCCTCTGATGATTAAACAGGAACCCAGAGATTTT
+
BC@DFFFFGHGHGFIDGEHHHHIIGIJJJJJJJIJJIJJIJJJDGIGGGGGHGDFFFFEEEEEEDCBDDDDDDDDEDEFEEDDDDDDBDBBBB@@BCDCDD
@6K7
AAAAGAAAGAAAAACCACAAGGACAGAGAGAAAAAAAAAAGAGGAATCTCATTCTAATGATCAAAGTCCACAAATTCGAGCATCACCTTCTCCCCAGCCCT
+
@CCFDFFDHHHFHHGGGIIJIIIGIGHFDGBDHIGGGGIHB;BDBDFCA>CAECCEECCDCACDDA5>CCAABDCCCD@C<BCACCDCCDCDDD><2ABD9
@6K8
GTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGC
+
C@CFFFFFHHGHHJJJGHIJJJJIIGIJIIJJIGIGHIHIEGIJIIJDHIIJJJJJJJGHIJJHHHHEFFFFFFDEEEEEEDDDCDDDDDCDCDBDDDB
@6K9
CAGGGCCTGTCTCCTGCAACCCCTTTGAAACTTGATCCTCTAGGGCCCCTGGCCTCTGAGGTTTGCCAGCAGCCAGTGTTCATTCCGAAGAAGGCAGCCTC
+
>>=AA;<?<2A72<<A3+?7C8<2<@B<71117?A4*1000?**93).>B;7>=7.>)));)6>A3.=)(...;((((5(------(8,''5(,(+82((+
@6KA
TGGAGTTTCACCCAACAGATGCAAATACCATAATTACATGCGGTAAATCTCATATTTTCTTCTGGACCTGGAGCGGCAATTCACTAACAAGAAAACAGGG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJIJJJJJJJIHIJJJJJJJJJJJJJJJJJJJJHJJJJJHHHFFDDDDDDDDDDDDDDDDDDDDDDDD
@6KB
CAACAAGCTCCCCGGCGAGAAGCTGGGCCGCGTGGTGCACATCATCCAGTCACGGGAGCCCTCCCTGAAGAATTCCAACCCCGACGAGATTGAAATCGACT
+
@<@DDDD==ADHFGGHDGD:@;???;FEHGEG=><6;;6ACCCCCCC;;;:ACB=805;@?<?BB?>?CA@AACACA@CBBBB59<5998:ACCC@C<?@<
@6KC
TACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTT
+
@CCDFEFFHHHHDHGEEFIIJJIJGIIIIIJIJJIJJJJJJJIFEHIIIJJIIJIIIIIIJJIJJIHHHHHFFFFECEEEEEDDDCDDDDDDDDDDDDCD
@6KD
CAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJIJIJJJJJJJJGIJJJJJJJIJJJJJHHHFFDFFFEEEDBDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDD
@6KE
CTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCT
+
CCCFFFFFHHGFHJJJJJGJJJJJJJJJJJJJJJJFHJGIIIHIJIDCHIJJGHHHHHFFFFEDECEEDDDDDCCDDCDDBDDDBA@BDCBDDDDCDDDDC
@6KF
CAGTAAGGTACGGAGTAACTGTCCAAAAGCCATGAAGAGATTAATGGCAGAGTGCCTCAAAAAGAAAAGAGATGAGAGACCACTCTTTCCCCAAATTCTCG
+
@<@4AABBFHD:CD<<CCECG@:CBFEBGFGEHA><?1?):?40?DDHIDHI88<B=B<=@@FG;2@E)?;7))..7>5((,,;=;@C(,>398<55,>42
@6KG
TCCAGCCTGAGAGCACTCCCAGTTTGGATGCTGGACTTGCAGAGCTGGCTCCTCTGCAAGGACAAGGGTTAGAAAAGCAAGTCCTGGG
+
@@@F?A?DHDHFFEBGEEGEIIEHHIFDGIIIDGGHEGDH@CEHIIID@FFHIIGDGIGGGIHIE@AC?CB@@DDEEECCC>AA;ACB
@6KH
CTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAA
+
@@@FFFFFGBHBHHGGHIBHHHGGGIIIIGGIGBDHGGIGGGIGHGCFGGIIIJGGEHIIJGGHHFDCEDEEDCCDDDDDCBCD:@CCDDD@C>ACCDDD
@6KI
TTTATTTCATTGCATCAGTAGTAGTACTATTTAATTATGAGGAGAGAACTCAGCGACACTACCTGGGCCATACAGACTGTGTGAAATGCCTTGCTATACAT
+
<@@DFDF?FBHHDGGHGHA<FAHHHHGIIIG@HHIEBFEHIBD1HDAEGAEEDBAGGHGGGHGCEHIIIEEAE@@C;?DA@6@@DCCCCCCCCACCDECEE
@6KJ
CAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATAT
+
CCCFFDEFDHHDHJIIIGGIIIJJJIIJJJJJJJIGJIJGIHIIIJJIIJHIJJJIIJJIJIIJGHHHFFFFCFEEDEECCDDD@BCDDDDDCDDDEED
@6KK
ACCTTCTGCACGTGGCTCGGGACATTGCCTGTGGCTGTCAGTATTTGGAGGAAAACCACTTCATCCACCGAGACATTGCTGCCAGAAACTGC
+
@@@DDDDBHHGH?B=EBADEHGGGIGIIGCH?FHGEHF@GHDFEGHGD@@FFHHHH?;A>ACCC@DDFCCA??@CCC@CA>C@CCB>C>::>
@6KL
AGGAGATGTACCGCCTGATGCTGCAATCCTGGAAGCAGGAGCCGGACAAAAGGCCGGTGTTTGCGGACATCAGCAAAGACCTGGAGAAGATGATGGTTA
+
@@<DDDEDHFFHAFHBFHHECHEHIGICCFHIIEGEGGIIIGGAGGHGIIGGGHHGFDC@BDCCD@=@@CDDDCCDDDCDDCDDDBCDCAACCDDCCCA
@6KM
GGACGTCCTATGTACCAACGCCAGATGTCTGAGCCAAACATCCCCTTCCCACCACAAGGCTTTAAGCAGGAGTACCACGACCCAGTGTATGAACACAACAC
+
CCCFFFFFHHHHFIJJJIJJJJJJIIJJJFIJJIGIJJJJJJJJIJJJJJJJJJJJJGIHHHHHFFFFFDDDCCDDDDDDDDDDDDCCCDEDECDCDDBBD
@6KN
CTGATATAGTACAACGAATGGAACAAGAAACACAAAGAAAGTTAGAACAACTCCGGGCAGAGCTGGATGAGATGTATGGGCAGCAGATAGTGCAAATGAA
+
@@CBDBBDDCDHHGDFGGGFFGGFGFGGCHIGGIIHHIIGGIHGDHEIHGCGHGHIIIGIEC;AED;@DDEECC>ADCCBDDDDD?CCA:5;CCCCACCD
@6KO
CCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATG
+
CCCFFFFFHGFHGIIJJJIJIJIEEGHGJJJHIGHIJJJJIJJIIIGGGHHJJJIJIJJJJIJHGHFFDFEEEDEEDEDDBBBDDDDBBDDDBD@CCDDED
@6KP
CACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCC
+
@@@FFADFAHAFFIGGHIIIGIFIIBFGGHIGGIDHGIGGGIGHIIIIIIIIEGIHIIIGGIIGIIGECEHGGGFFFFFECCCD@BDBDB?ABDBDDA@B
@6KQ
GAGGGCTCCAGCTTGTATCACCATCTCCATATCATTGAGACCAAATTTGAGATGATCAAACTTATAGATATTGCACGACAGACTGCACAGGGCATGGATT
+
@@@DFFFFHHGHHIJHIJJIJJJJJJJGIJIIIIIGGIIIGIJJIJFEHGIJIJIJJIJJJJGIJIJJIJJJGFGIHGEFDEECEECDDDDDBDDBDDDD
@6KR
ATTTCAACCACAGCAGATGACTGCAGTTCAGAGGTAAATGGTTGCAGTTTTGTGATGAGAACAGGAAAGCCTACAAATTTATTAAGGGAAGAAGAATTTGG
+
@@@FFFFFDDHHGIIIGAFGFEHHEDAFGHIHGH@FFFGHI?FDHGHBFHGH?BGHHGGIGEHHECHGGEHGHDHGHFFFDFFFEECEDDD@A?>CA@CDD
@6KS
CAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCC
+
CCCFFFFFHHHHHJJJJJJJJJGJIJJJIIIIJIJJJJHGIIJJJJJJJJJJJJJJJJJJJJJIFHHHHFFFFFFEEEDDDBBCDDDDDCDDDDDDEDDD
@6KT
CAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGC
+
?=?DDDDDHDFHHIIIFII@FHIIIIIIIIDFBGIIIIG<GHCGIGIIEHGHIFIIHGEGHIIIIHDHEEEECCCCCC@C>@CCCCCCCCCCCCCCCECB
@6KU
AACAAATCAAAGCTCATGATGGCAGTGTGTTCACACTTTGTCAGATGAGAAATGGGATGTTATTAACTGGAGGAGGGAAAGACAGAAAAATAATTCTGTGG
+
@@@DFDFFGHHGGJIIJJIIIJIGGHGHFHGIJJJJJJEGHIGGCHHGHIIJGIHIFGGIIHHIJGGIHGCDGGFEFBDDDCEEDDCDCBBDDDEDEDDCD
@6KV
CTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGC
+
CCCFFFFFHHHHHJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJIIJJJJJJIJJJJHHEHHHFFFFFFDEEDDDDDDDDDDDDDDDDDDDDDD
@6KW
CTTTCCCCAAATTCTCGCCTCTATTGAGCTGCTGGCCCGCTCATTGCCAAAAATTCACCGCAGTGCATCAGAACCCTCCTTGAATCGGGCTGGTTTCCAA
+
CCCFFFFFHGHHHJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJIJJHHHFFDEEEEEDDDDDDDDDDDDDDDDDDDDDDDDCDDDDED
@6KX
TGAAAAGCAAAGGAACACTTTTTCATTTGCTGAAAAAAAACTTTGAAGTTAACTATCAAGAGTTACAAGAGGAGTATGCTTGCCTTCTCAAAGTAAA
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJIJIJJJJJJJJJJHHHHHHFFFFDDD@CDEDEEDDDDDDDDEDDDCDDD
@6KY
CAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTC
+
CCCFFFFFHHHGHJJJJJJIJJIIJJIHJIEFHIJJIJJGIJJJJJIJIIFGIJJJJJEIIGIIFIHHHHFFFFFDEACEEDDDDDDCDDDDDDDDDDDCD
@6KZ
CTATGATAAACTTAGCCGTTCACTCCGCTATTACTATGAGAAAGGAATTATGCAAAAGGTGGCTGGAGAGAGATATGTCTACAAGTTTGTGTGTGATCC
+
@CCDDEBDDFHGHIIIHIIIDGIHHGAEHIGGGGFDFGIIHI>GFG3?DFHIDHIGIIG=CFHDHGHFGHF=BCC@A>@C@CACCAC@C9<?B??@@AC
@6L0
GGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATC
+
@@BF=DDEHHGHGIIGGIJJIJIJIIJIIDIHIIJJJJJIJGHIJJJJIJJJJJJIIIGIJIJIIJHGFHHHFFFFFFEEEDDEDDDDDCDDDDDDDDDDD
@6L1
AGGAAAACACGACATGTGAATATCCTACTCTTCATGGGCTATTCCACAAAGCCACAACTGGCTATTGTTACCCAGTGGTGTGAGGGCTCCAGCTTGTATC
+
CCCFFFFFHHHHHJJJHIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHIJJJJJJJJJJJIJJHHGHHHFFFDDE>A?CDDDDDDDDDDDDDDDDEE
@6L2
CAACAAGCTCCCCGGCGAGAAGCTGGGCCGCGTGGTGCACATCATCCAGTCACGGGAGCCCTCCCTGAAGAATTCCAACCCCGACGAGATTGAAATCGACT
+
<;;DDDD?HH>??:EH<C@?DD@HA;AAG@AH:=B(;>C;>CCAC9;AACC>A==?8@B?BC??BC>CCC>ACC:ACC?9@>BBB@BB98@:>@:>:8<<<
@6L3
GCTGCTATTATTTTTCTTCGTCTTTTTAGGAGGAGGTTCCTTGGCTTTGCTTTTTTTATTCTCTTCCACTTCCTCTTTCCTTTTGTGCTTTTCTTTTTTCT
+
CCCFFFFFHHHHHJJIJJJJIJJJJJJJJJGIJGHJGGIHIIJJJJJIJJJJJJJJJIJJFHFHHHHDDFFFEEDEEDECDDDDDBDCDDDDCDDDDDDDD
@6L4
GTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACA
+
CCCFFFFFHHHGHJJJIJJJIJIIGIJJIIJJIIIIJIJJIIGIJJJJJJJJJJJJIJJJJJIJJIIEHFHHFFFFEEDDDDDDDBBBC@CC@CDCCDD
@6L5
TATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATC
+
@C@DDDDDHDFHHGJIIEGHGG@AHEHIIGGHGCHEHFGEIGDFHDBBDGGIBHIEGGIJDGIIGEHEGFFDEFE@CEEDC?CDB==8@DBCACCCCCAC
@6L6
CAGGGACTTCAGACATTAACCATGACAAATTCAGGCAGTACTCAGCAAGGTACAACTATTCTTCAGTATGCACAGACCTCTGATGGACAGCAGATACTTGT
+
CCCFFFFFHHGHHJJJJJJJJJJJJJJJJJJJJJJIJJIJJJJJJJIJJJFHIJJJJJJJJJJJJJIIJJJJEIGIIHHHHHFFFFFEEDDEDDDDDDDDC
@6L7
AACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGG
+
@@@DADDDDABHFEFGGG:EGEGBBDEGGEGEHCGGGG?GHACECIIFGHICFIII9@==;A>AEH@BEBCACCCCB<C@??C;>A@CACBBB3?@B@CCC
@6L8
CTGCTGCCCGTAGCTGCTGCTCTGTTGGCTATATTGACTTGGAGCTTGGCTGTAGGATCCAGTTTGGGGTGGGTAACTAGTGGGAGGCTGCTGCCCATAGC
+
BCCFFFFEHHHHHIJJFHIGIGGHGGGIJJIGDGGIAHEHJJFEGGGGHIJI8=CF@CHGGHGGHIGIH'9AD;CCCDDD;ABDBDBBABBCDDDDCDDA@
@6L9
GTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACA
+
CCCFFFFFHHHHHJJJJJJJJJJIJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHHHFFFFEEEDDDDDDDDDDDDDDDDDDDD
@6LA
GGGAGACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTT
+
@?@DB8DAFFFFFFGCE?EEGII0CG:FG6?BF;;F=FFCFAECEEEFDDDC<<88A@AA5@:@BBAB@5>AB?2@>A>ABBB>@>BBBBB@@<:>::@DB
@6LB
GTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGC
+
?B@FFFFDHFHHGGHIIIIIHFJJJJIIGIJJJIJJIIGGIJIIJIIJIIHJHGHFFFFEEEEECACDDDDDCCDDDDDBDDDBDDDDDEDBDCDDBBDDD
@6LC
AAAAATAATAGCAGCAACAGCAATGTGAGCAAGAAGGAGCCAGCGCCCATGAAGAGCAAGCCCCCTCCCACGTATGAGTCGGAGGAAGAGGACAAGTGCA
+
@@?BDDDEFFBDDDDGHDCCCDFEEHFBCFBBE>?DHIIEBB;FEGIGBHACDFHIIGIEECEEE9==AA?BBDD?@C;>;;59<?A@D<?8??8A4>CC
@6LD
AGACATGGAACGTCACATCAACGAGGAGGACACAGTGCCTCTTTCTCACTTTGATGAGAGCATGGCCTACATGCCGGAAGGGGGCTGCTGCAACCCCCACC
+
CCCFFFFFHHHHHIIIIJJJJJJJJJJJJHIJJJJIJJJJJJJJJJJJJJJIJJJJJJJJJJIIHHHHFFFFFFEDDDDDDDDDDDDDCDCDDDDDDDDDD
@6LE
CAGTAAGGTACGGAGTAACTGTCCAAAAGCCATGAAGAGATTAATGGCAGAGTGCCTCAAAAAGAAAAGAGATGAGAGACCACTCTTTCCCCAAATTCTCG
+
?@@BDFFDAFHFD?@AEFBFHHHGHHHEHIIIIGCH<GH@?BBGB<FHIE6?98=BB=EHAFAE@@CHA;A>@CE>@>;6;?BA3@CCDDC<??<:A5@><
@6LF
ATTCGATGGAGACATCAAACAAGAGCCAGGAATGTATCGGGAAGGACCCACATACCAACGGCGAGGATCACTTCAGCTCTGGCAGTTTTTGGTAGCTCTTC
+
C@CFDFDFDHFFHJJIJIJJIJJGGIJJJJJIJJJIHIIIIIGHGJIIJJGJJIIJJFIHHFDDDDDDDBDDDDDCCDDDDDDDDDDEDDDDBDDDCADDC
@6LG
ACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGACTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCA
+
07(<(<5;<??9)2).@)(<><7(.2@@1:9<?=?=<<?76)93)9<3).9>(<9=3>)6>93673(..8)3.9).,'9;8;;<0;;262;=5:</:/8
@6LH
CCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCAC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJIIJJJJIJJJJJJJJJJJJJJJJIIJJJJJJIJJJHHHHFFFFEEEFEEEDDDDEDDDDDDDDDDDDDDDD
@6LI
GTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCC
+
C@CFFFFFHHHHGJJJJJJJJJJIJIJJJJJJJJIJJJJJIIJIIJJJJJJJJJJJJIIJJJJJGHHHHFFDCDDDDCD@CDEEEEFDDBDDDDDDDDDDD
@6LJ
CTCAGACAACTAAGACAGATGACCCCCAATTGAAAAGAGAAATAAGGTTAATGAAAAACAGAGAAGCTGCTCGAGAATGTCGCAGAAAGAAGAAAGAATAT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJIJJHHHIJJIIJJJJFHIJIJJJJJJJJIJJIJJFHHHGHFFDDDEDDDDBDDDDDCCDDDDDDCDDDE
@6LK
GGTGACAGTGCTTATAAACGAAGACAAAGAGTTGGCTGAGCTGCGAGGTCTGGCAGCCGGAGTAGGCCTGGCTAATGCCTGCTATGCAATACATACTCTTC
+
???BABD?CADDDED<EE@?)3ACF>ABD3C:19:C?DDD3D;9?@DAD>ACC=CADAAAD@;A>A(;;=(5<A>AAA:>59:::A3:>:>>A:4444:A(
@6LL
CAGATAGCAGCTACCCCATGGACCACAGATTTCGCCGCCAGCTTTCTGAACCCTGTAACTCCTTTCCTCCTTTGCCGACGATGCCAAGGGAAGGACGTCCT
+
@@@BDDFFBFHGHIGIIG@;FFEEIIIIIIFHCBFGAHIIGGIHCHGIIIIII@HEHDEEEEDECEECCEC>@>AC?BBBBBBBCCCBBC@A@BBBBBBBB
@6LM
TCTCATTCTAATGATCAAAGTCCACAAATTCGAGCATCACCTTCTCCCCAGCCCTCTTCACAACCTCTCCAAATACACAGACAAACTCCAGAAAGCAAGA
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJHHHHHHFEFFFEEEEEDDDDDDDDDDDDDDD
@6LN
CGTGCTGAGACATTCTTCTGATAAAGTATCTAAACTAGAAGGTCAAGTAGAATCTTATAAAAAGAAGCTAGAAGACCTTGGTGATTTAAGGCGGC
+
@@@DFFFFGGHGHJGGIIJJIJFJJGCFDCGGHIJJJIHJIIDHHIIAGHHJIJJIGGIJGHHDEGGJJJJJJIJJIIIHFHHHFFFFFFFEDDD
@6LO
AAGGAATTATGCAAAAGGTGGCTGGAGAGAGATATGTCTACAAGTTTGTGTGTGATCCAGAAGCCCTTTTCTCCATGGCCTTTCCAGATAATCAGCGTCC
+
CCCFFFFFHHHHGFJIJI<CCHGHJIJIJIIHHIIJJJJIIJIIFHIIDHHIJJJJJJJJIJJIJIJJIHEHHHHFFFFEFDDDEEECCDDD<CCDDDDB
@6LP
GATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTAT
+
@@@FFFDDFGFHHJJGIJIJIIGAEHIJJEIJJIJGIIIGJIIEHGIJJIGIJJGHJJIIJEIFGGAEHFFFFBEFDEEDDDBDCACCBDDDDCDC38CCA
@6LQ
TGAGGGTCCTGCACCTCCATTTGTGACAGCATCTAATGTGAAGACCATTCTGCCCTCTAAGGCTGTTGGTGTCAGCCAGGAGGGTCCTCCAGGCCTTCCGC
+
CCCFFFDDFHHHHJJJIJIJIJIHGHIIGIIJJJJJJIGIIGGJJJJJJJJIJJJGHGGJGFHIIIGGGCHEHECEHFFFFDDD;CBDDDDC?BBACCDDB
@6LR
TTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGC
+
CCCFFFFFGHHHHIJJJJJIJJGIJGJJGHIJGIIIJJJJJIIIGIGIJGJGIJHIIIIJJIIHEF?CFFDDCEE;@CECDDDDCCDBDDDDDDDCDDBD?
@6LS
CCTCCATGCCTGTCACTTCCTCCAGCTTCTTTGGAGCCGCATCACAATACTGGACCTCCCCCACGGGGGGAATCTACCCCAACCCCAACGTCCCCCGCCAT
+
CCCFFFFFHHHHHIJJJJJJJJJIJJJJJJJJJJIIJJJJJJJJJJJJIJJJJJJJJJJJJJGHFFDDDDBDDDDCDDDDDDDDDDDDDDDDDDDDDDDDD
@6LT
ATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCA
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJGHIJJJJJJJJJJHHFFFFDDEEDDDDDDDDDDEDDDDDDDDDDDDDDDDDDEDDDD
@6LU
AAGTTCTGGAGTTTGTCACCAGTGGAGGCCGGATGGACCCACCCAAGAACTGCCCTGGGCCTGTATACCGGATAATGACTCAGTGCTGGCAACATCAGCCT
+
BCCDFFFFHHHHHJJJJJJJIJHHJJJJJJJJJIJJJJJJIJJJJJJJJJIJJJJHHHHFFFFCDEFEEDDDDDDDDDDDDDDCDDEDDDDDBDDDDDDDC
@6LV
GGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTT
+
88:BB:A?AAF;?C,2+C<AC:AFB>H<9:CFGID@F:?BG?4B*09DD@F@B?7;.8=8==6=6=C7AEF>7@D?;.;63(,;'8@/'::(44:A>A3>
@6LW
CTCACCTCTCAGACAACTAAGACAGATGACCCCCAATTGAAAAGAGAAATAAGGTTAATGAAAAACAGAGAAGCTGCTCGAGAATGTCGCAGAAAGAAGA
+
CCCFFFDFFBHFHIIJJGGIIJIIIIE@HHIJJIJEGIJIJJJIEFFHHHJIJJHIJJJJIIJJIJJFHEFFFFFFFDEDDBBD@>:>ABDDDDDDCDDD
@6LX
CCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTT
+
CC@FFFFFFHGFFIIIGIIIJJJJIJIFHHGHIIIEHJJJJJJIGIJJJGGGEGIG=BFFEEEDDDBBBDBDDDDDDDDACCCDDDDDDCCCCDCCACAC
@6LY
CCTGAAGCCAGTCAAGAGGCAGGGAGCAGAGGCAATTCCTTTTCTCCTCTGTTGGAAACCATAGAACCTGTCAACATACTAGATGTTAAAGATGACTGTGG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJIJIJJIJJJJJJJJJHHGGHHFFFFFEEEEEEDDDDDDCDFEDDDDDDDDDDDD
@6LZ
AGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTC
+
CCCFFFFFHHHHHJGHJJJJJJJJJHIJJJJJJJJJJJJJIIIJJJJJJJJJJJJJJJJJJJJJHHHHFFFFFEEEEEEDDDDDDDDDDDDDEDDDDDD
@6M0
CGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJDHIJJJJJJJJJHFFFEDDDDDDDDDDDDDDDDEDDDCDDDDDDDDDDDDDDEDD
@6M1
CTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTT
+
?@@DDDADBDFFDGGHG:CABCDGEBHECE@GCGA>GDFGCBFFBDFEEGAF>AEGECC@AAEEDCDCEEED>@DA<>>;;>@A:>;@;>@99;;99>C>@
@6M2
GTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTAT
+
CCCFFFFFFHHHGJIJJJJIIIJJJJIJJIJFDDGGGHIJJFJIIGICHIIJIGAAEHHGFDFCDCECEEEDCBCDDCCCCDDBBB@BDDDCDCCDDDDD>
@6M3
CACCAGAAGTCATCAGAATGCAAGATAAAAATCCATACAGCTTTCAGTCAGATGTATATGCATTTGGAATTGTTCTGTATGAATTGATGACTGGACAGTT
+
81:4=DDD8DD,C,2A::CD9EECE3C92228*@*?:)::91:B<449:?DD9D*BB48/99?DBBCDCC3@CD4=:7=A=AA37=3==?D>ADA(;;A;
@6M4
CTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTAT
+
CCCFFFFFHHGHHJJJIGGIIJJJJIGGIIJJIJJJJJJJJAHHIIJJJJJHEHHHHFFFFFFEEEEDDDDDDDDDDDDDDDDDBDDDDDDDCDDDDDDDD
@6M5
TCTGTATGAATTGATGACTGGACAGTTACCTTATTCAAACATCAACAACAGGGACCAGATAATTTTTATGGTGGGACGAGGATACCTGTCTCCAGATCTC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJGJIJJJJJJJJJJJJJJJJJJHIJJJJJJJJJJJJJDHIHEFFCDDBCCDDDCDDDCDDDCDDDD
@6M6
GCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGC
+
@@@FFFFFGHHFHJHHGIIGIJGIJJJJJJIEHJJJJJJIJJDHGGIIIJGHIJIIJJICGDHIHEEHHFFFFDDABBCDDDCDCBCDCDDDDCDDDDDD
@6M7
CTCCTCTGCAAGGACAAGGGTTAGAAAAGCAAGTCCTGGGATTGCAGAAAGGACAACAAACAGGGGGTCGTGGAGTGCTTCCTCAAGGGAAGGAGCCTTT
+
C@@FFFDDHDFHHJJGGFHEFBFHIJJJJJICDHIJCGHJ>FFHIJIGHHJJIJGHEIIID@CEEEE;@;8;=?B><>A@>CDDDDDDDDBBBBBDBDCC
@6M8
CAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATG
+
@@@DFFFFHHHHHIFHIJJJJIJIIJJIJJJJJJJJJJJJJHIIJJJJIJJGIJJJIJJIJJJGJHHHHHFFFFFEEEEDEDDCDDDDDDBDDDDDCDDED
@6M9
CCTGTAACTCCTTTCCTCCTTTGCCGACGATGCCAAGGGAAGGACGTCCTATGTACCAACGCCAGATGTCTGAGCCAAACATCCCCT
+
@@@DBDDFHAHHGBGBIGIIIIIHGGGIIIIIIIGGBEEBFFHIGIBG=CG>;AECC;=B1<<>B=ACDCECCCCCC?CBBCCCBBA
@6MA
CCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHHHHHFFFFFFEEEEEDDDDDDDDDDDDDDDDDDDDDDDDD
@6MB
CAAGGATTTCGTGGTGATGGAGGATCAACCACAGGTTTGTCTGCTACCCCCCCTGCCTCATTACCTGGCTCACTAACTAACGTGAAAGCCTTACAGAAATC
+
@?@FFFFFHHFHHG2AEHHGGEDGFEHIGIIICGH?BGGDDGEG@FGGHGEIHE?DFEEEEEECCCAABCCCC@CC@>CCCBC@ABC>CBCCCC@@CCC:C
@6MC
TTATTGGCTCAACTTTCCTCACTATCTGCTTCATCCGCCAACTAATATTTCACTTTACATCCAAACATCACTTTGGCTTCGAAGCCGCCGCCTGATACTGG
+
;;?D7;DDDHBDHE@CCACEIGHG<A<CHHIIGHIIJGJGGGHCH>DEA9<FH>B@GGG@FCFGACGGIIGE4))==3?@B?AAABBB=?BD-<?4>CC:@
@6MD
GTAACTCCTTTCCTCCTTTGCCGACGATGCCAAGGGAAGGACGTCCTATGTACCAACGCCAGATGTCTGAGCCAAACATCCCCTTCCCACCACAAGGCTTT
+
@@?DFDDEFFFFHIJGGIIGIEEHGGJI;?BF>?DBFGEAHGIGHEGEG@@@AG:CH;BCCD=CD>A>ACC@??CDAB@@CBBCB?ACDBBDDDDDBB@?C
@6ME
CCGGCTCAGTACTACCCGTCCCCCGTGCCCCAGTACGCCCCGAGGGTCCTGACGCAGGCTTCCAACCCCGTCGTCTGCACGCAGCCCAAATCCCCATCC
+
?@?=+0=ADBFDF:AFD?FF@FGIB??0BBBB8*9B?FFIIIB4-4(.=>66;88?/=/(5?@>ABBB@;>@>9BB<B:@@@5&58@<<BBBBABB???
@6MF
CATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATAT
+
CCCFFFFFHHHHHIJIJJIJJJJCGHGIJIJIJJDGIIIIIJJJJJJJIJJJJJJJJJJJHIFIJJHHHHFFFCDDDDDDDDDDCDDDDDDDDDCDCCDDD
@6MG
CCAGTGTACATTCCGAAGAAGGCAGCCTCCAAGACACGGGCCCCCCGCCGGCGTCAGCGTAAAGCCCAGAGACCTCCTGCTCCTGAGGCACCCAAGG
+
>;:<22222@7><<?C=<C<+@7C=<1:@=B;=A?==448:-7->:4=<6=:5)00&(5+8<83(2+222+(+23:9(:8++3(8(+(++222(2+8
@6MH
CTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTAT
+
CCCFFFFFHHHHHJJJIJJJJJJJJJJJJJJJJJJJJJJJJFHIJJJJJJJHEHHHHFFFFFFEEEEDDDDDDDDDDDFDDDDDDDDDDDDDDDDDDDDDD
@6MI
ATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCC
+
CCCFFFFFHHHGGJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHIJJHHHHFFFFDDEDDDDDDDDDDDDDDDDDACDDEDDDDEDDEDDDD
@6MJ
GGATCAGTTTCTAAAGTAAATAAAAGTTTTGGTGAAGAATCAAAAATAATGGTGGAAGATAAAGTTTCTTTTGAAAATATGACTGTTGGAGAAGAAAGTA
+
?<@=ABDBFDFHFA<@<AF@@?:<:CAFCEEEACGHI@@<DGGD?FB909BB*9D9*?BBC=BC8B@FFEGGCCHCE;)==.==@?>@B;>;@;5;3;(5
@6MK
CAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCC
+
C@@FFFFFHHHHHIIGIIIJGGHGIIIIIIJJIJJJIIJGEHIGFFGGHIGGGFGHE?BEDFFCEFEEEDDDDDDBCACCCCDDA@BA@CDDA@CCDDDDD
@6ML
CTTCAAGAAAAATTTGCACACTTGAAGCAGAGAATAGCATTCTTAAAGATGAAAAGAAAACCCTTGAAGACATGTTGAAAATACATACTCCTGTTAGCCA
+
@@@D?DDDDF;<CEBG@EHEHIGD>FABCB@FEEGD@FHEGGGEFG<?B@?BFBBDHBGEEHGIC>CE;==7=CHEHEEC@CDDDDCCACCCCCC>@@>A
@6MM
GAGCTAAACAGAGAGCTGGAAGAAATGAGGGTTACCTATGGGACTGAAGGACTGCAGCAGTTACAAGAATTTGAAGCTGCCATTAAACAAAGAGATGGCAT
+
@<@DBFFFHHHGFEHGHGGJJHJIJIIAHIGIIFHBFADFGEFGG??DFCHI>FHGJGECEEECECGEEHHHHEFDDFFECC@ACC@@CD?A>C<>AC<AD
@6MN
CATTTATATGAGGCAAGAAGGCTTCCTGGCTCATCCCAGCAGAACAGAAGGCTGTATGTTTGAAAAGGGCCCCAGGCAGTTTTATGATGACACCTGTGTTG
+
CCCFFFFFGHFHHJJJJJJIIIJIIJIJIJJJJJJIJJIIJIJJJJIJJGIIIJJJIJJJIGJJJFGIFFHFFFDDDCD?CDDDDDDDDDDDDDDDCDACB
@6MO
AAAAAAAGAAAGAAAAACCACAAGGACAGAGAGAAAAAAAAGCGGAATCTCATTCTAATGATCAAAGTCCACAAATTCGAGCATCACCTTCTCCCCAGCCC
+
(0(25-;-@()2.(;:>:5:533?<=:<=<<37;)::></-:(,'93,0;===(,,58=(8075((66:6:2:(8/2/25(&5:6/:<52(628897-59<
@6MP
CCTACATGCCTTCCTACCATGCCCACCAGCAGAAGGTGAACTTTGTCCCTCCCCATCCATCCTCCATGCCTGTCACTTCCTCCAGCTTCTTTGGAGCCGC
+
CCCFF?DFHFFDHEGIHHIEGEAGHDAFFCEGHHGICGHHICGHEHEHGAFGIGFHIIHIGHGEHHCG@HHEHEHFFFDEBECECCCCACCCC?39?@BB
@6MQ
GACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTG
+
CCCFFFFFHHHHHJIJIIIJIJJJJJJJJIJJIJJJJJJJIJJJJGIJHIJIJIJJJIHHHHGHFFDFFFEEEEECDDDDDDDBD<ADCCAC@C?@ABDD@
@6MR
GAATTATGCAAAAGGTGGCTGGGGAGAGATATGTCTACAAGTTTGTGTGTGATCCAGAAGCCCTTTTCTCCATGGCCTTTCCAGATAATCAGCGTCCACTG
+
=71?2<,,2,2+2A1<A==+=)+<+:)1:*??A??4A?*0:0*09/9)09;>>).>9A;A)==;;AAA>AA;?;;2;>@>>@B?;=;;=??9>68(388:?
@6MS
CGCCAGATGTCTGAGCCAAACATCCCCTTCCCACCACAAGGCTTTAAGCAGGAGTACCACGACCCAGTGTATGAACACAACACCATGGTTGGCAGTGCGGC
+
??<DB:?=A<?AA<CEEF+<CF><CCEGGHFBDHIGIGGBEAG?BFFBGDHB;;@=F4=@--::BDEC;CB>(65>5==?<?<8?>>>:>?5AC?94:<9>
@6MT
CTGATCATCAGCAAATTCAACCACCAGAACATTGTTCGCTGCATTGGGGTGAGCCTGCAATCCCTGCCCCGGTTCATCCTGCTGGAGCTCATGGCGGGGGG
+
@@@DDDDDHFBAA@FFBCHIEEGCGGGGGIGCGHIEGIFIIIICHEGGBGEG9DDH@AGA>=EEBCEECCCBBB@ADDCCCCCCCBBC8:C3@:A@<5505
@6MU
CAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTT
+
?;?AB:BDDDDDDBE@EDFIDDA3A99;F;EEEI8?:09DBDDCE@DDDDDADCEE@ACAACCDDDDD@DD<;>@@@A>AA????1592<???<<>?>A>>
@6MV
CCGGGCCTTCCCAGCTCACCTCCCTCCATCGCAGTCCATACCAGATAGCAGCTACCCCATGGACCACAGATTTCGCCGCCAGCTTTCTGAACCCTGTAACT
+
<@@DDDFDHDDFCDDBCEEBHHGBDFGDDECFGGBDDHGDHEGD=GEAFBEEH@@GGEH=77;A@?BEE;CE@@=;?=BBBBBCCC>AACACBBBCCA@@4
@6MW
CCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAG
+
===AAA<<A=BA<=++2<<A?=@=7=;7<<>A=A=>AA7::*9A7A=77?BB>=2.76;=>A>BAAA>A7???@?>>>>3>===;6==:??==83888=
@6MX
CCTCTCTCATCGGGAAGACCTGGCTTACATGAACCACATCATGGTCTCTGTCTCCCCGCCTGAAGAGCACGCCATGCCCATTGGGAGAATAGCAGATGTGC
+
@@@ADDFFFDHADHEGGGIIEGH@FFH@??FGFHIIC@GIGH>?BFDCGGGH@<.BAHEBEHE>C@B>CCDDBBDCCCA@A@CCDB8<ACCDCCCDDC3>@
@6MY
CCCAGTGCTTCGTTCCCTGGCCCGGCTGAAGCCCACTATGACCCTGGAGGAGGGACTGCCATTGGCTGTGCAGGAGGGGGAGCACACCAGCAACTTTGACC
+
@@@DD?DDHA?D:A<ACACA?>GFGCADFEH>DFGIIFDIII@;BFG@GH@CGB=B>B@;@>@ACC3?(;5;>@85'05>)90889828???C<CA>@34>
@6MZ
CTGGAGCGCTATGTCACCTCCTGTTTGCGGAAGAAAAGGAAACCTCAAGCTGAGAAAGTTGATGTGATTGCCGGCTCCTCCAAGATGAAGGGCTTCTCGTC
+
@C@FDFFFHHHHHJGIJJJJJJJHIJJJIJGIJGIJJJJJIIJJJJIIGIIJGHIHHHHHGFFFFFFFEDECDDDBDDDDDDCCBCDDDDDDBBDDDDDDD
@6N0
CCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTAT
+
CCCFFFDDHHHFGJJJJJJIJJJJJJHIIJJJJJGIIIIJJJJJIJJJJIJHHFFFFFFEDCCCDDDEDDDDDDDDDDDDDDDDCDEDDDDDDDDDDDDDC
@6N1
CCTCCTGAGAAGCTCAAACTGGAGTGGGCATATGGTTATCGAGGAAAGGACTGTAGAGCTAATGTTTACCTTCTTCCGACCGGGGAAATAGTTTATTTCAT
+
CCCFFFFFHHHHHJJJJJJJJJHJFHIJJJJIJJJGIJJJJIIJJJJJJJJJJHJJIJJJJJJJIJJJJHHHHHHFFFFDDDDDDBDDDDDCDEEDDEEEE
@6N2
TTCTTATTCTGAACAAGGAGCACAAGACAGTCCGACTCATCTAGAGATGATGGAAAGTGAGTTGGCTGGGAAGCAGCATGAGATTGAAGAGCTAAACAG
+
CCCFFFFFHHHHHJJJJJIIJJJJIJIJJJJJJJJJIJJJJJJJIIFGHGJJJJGHIDHEHFCHGHGJHHHFFFFEEEEEEDCDDDDCACDCDDDDDDD
@6N3
CAGAGAGCTGGAAGAAATGAGGGTTACCTATGGGACTGAAGGACTGCAGCAGTTACAAGAATTTGAAGCTGCCATTAAACAAAGAGATGGCATTATAACCC
+
?@?BD?DD?<3+AECFB4C9FFEF;FGF<DEGEE>FGI@FFFDBG@CBBFDIIC@BCF>CFCEEDD4@E?C9;AB@;@BBCCA>A=9@>>;ABB:A>A>><
@6N4
AAAAGCAAAGGAACACTTTTTCATTTGCTGAAAAAAACTTTGAAGTTAACTATCAAGAGTTACAAGAGGAGTATGCTTGCCTTCTCAAAGTAAAAGATGAT
+
CCCFFFFFHGHHHJJJJJJJJJJJJJJIJIJIJJJJJJJJJJJIJGHIJHJJJJJJJIJHIJGGGJGHFHB@DFFFEDDDEEDDDDEDDD>CCDDDDDDDE
@6N5
CCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGAC
+
CCCFFFFFHHHHHIJJJJIIJJJJJJJJJJJJJJJIJJJJJJJJJIJJJIJJJJJIIJIIJJJIJJJHHHHGFFFFEEEEEDDBDDDDDDCDDDDDDDD
@6N6
TACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCC
+
@CCFFFFFHHHHHJIIJJJCHIIJGGGGHEEGGFFGCHGGGFFHGIJJJIGGFHIJIIGIC;BEEGHHHHFEFFFDAED@CCACCDDDDCDDCACBDDDDD
@6N7
CTCCAGAGAGCCCAGTGCCGAGTTACGCTTCCTCGACGCCACTTCATGTTCCAGTGCCTCGAGCGCTCAGGATGGAGGAAGACTCGATCCGCCTGCCTGCG
+
CCCFFFFFHHHHHJJHIJJJJJHIJJJIJIJJJJJJJJJJJJJJJJJJHHHHHHFHFFFFDDDDDDBDDDDACDDCDDDDDDDDDDDDDDDDDDDDDDDDB
@6N8
AGCCAGCGCCCATGAAGAGCAAGCCCCCTCCCACGTATGAGTCGGAGGAAGAGGACAAGTGCAAGCCTATGTCCTATGAGGAGAAGCGGCAGCTCAGCTTG
+
?<=D;2BDFFFFB;AEBBEEB?EE;DFA@GCFGFIDB)=CFIIIAEAEEE>66;@?A;;55;;>;<?:>B5,;;ABAABBBB?BBBBBBBBB?AA@93>AA
@6N9
CCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTAT
+
?@?DD:BDDBDD>GBHFBHGEEDBBHH<BFEHIIDD<GBFHBDHFBBD<?F==BFGCCGIIGEAHEG@E?>CE;;B;>C@CA=C@>;;;AC88<9>59004
@6NA
GCCTTATTACCTGGCTCACTAACTAACGTGAAAGCCTTACAGAAATCTCCAGGACCTCAGCGAGAAAGGAAGTCATCTTCATCCTCAGAAGACAGGAATCG
+
@BCF1BDFGHHHHIJJJJJJJJJJJIJJGIIJJJJJIJJJJJJJJJJJJJJJJJJJJJJIIIIJIHHHHFFFEFFEEEEEEEEDDDDDDDDDDDDDDDDDD
@6NB
CTACAGTTATCCCCAGGTACCTGGGAGCTTCCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTT
+
CCCFFFDFHHHHHJJJJGHIIJJJIIJIJJJJJJJJIIJJJJIIGIIIJIJJJJIJJJGGIJIJJJJHHGHHFFFFCEEEEEDDDDDDDDDDDDDDDDDCD
@6NC
GACTGCAGCAGTTACAAGAATTTGAAGCTGCCATTAAACAAAGAGATGGCATTATAACCCAGCTCACTGCTAATTTACAACAAGCAAGAAGAGAAAAGGAT
+
@@@DDBBDAFHFFFHIIIGHIIIEGHGHIEHIIHGEIIGHGIIGIIEHGEEHIIBHGHCEHIIGIIIIECCEIIGFHGHE;?BF<CCE@CCC?CCACD??>
@6ND
CTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTAT
+
C@@FFFFFGHFFHFGHGIGGIJEHGEEHICFFF?FHCFGGI@AH@=CHGGHF.=EEHBDFFC>@@ACABBC@CA@CDDBCCC>@B?BABD?BDBD@A?CCC
@6NE
CGAGGCATGGAATTTAAACTGATTGAGCCTGAAGAGGTGGCCCGACGTTGGGGCATTCAGAAAAACAGGCCAGCTATGAACTATGATAAACTTAGCCGTTC
+
@@@DFDFDFBHFHIIIII<HGGGHHAHGAHI9BFGGI*??FBAEDAFAGHIHHHFDDEDDDEC@B@ACB<859@CDCDCD>@:@CC:ACC:>C:@@CB@BC
@6NF
GTCCTGTATAACCAATGGAAGTGGTGCAAACAGAAAACCAAGTCATACCAGTGCTGTCTCAATTGCAGGAAAAGAAACTCTTTCATCTGCTGCTAAAAGTG
+
===AA?A@CBCBB?AABA@C;3<A3?@=BBABB;ABBBA=B)0?A9==9AA9979A=<=8>=AA>B=A;5>A>>AA>@?>@@@?>>;>@>>;==;;;=9,;
@6NG
CTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTC
+
CCCFFFFFHHHHFGHJJJJJJGIIJJJJIJJJJIJJJJJJIJGIJIIJIJJJGIIJJIJJJJJJIIGIHGHGFCDDDDDDDEDDCCDDDDDDDDCDDDDDD
@6NH
ATTACAAGAACAGATTGTGCAAAAGAACCAAGAAATAAAAAACATGAAATTAGAGCTGACTAATTCTAAGCAAAAAGAAAGACAGTCTTCTGAAGAAATA
+
@C@FFFFFHGHHGIIIJHIEIIIJGGHGHIJJIIJJJJJJIJJJJJJJJJJJIJJJJJJJJJGGIJJJHHFHHFFEDDEDCEDDDDDDEDDADCCDDDDD
@6NI
ATGATGTGTCAGCACACCATGATTTGAATATTGATCAATCACAGTGTAATGAAATGTACATAAATAGTTCTCAGAGAGTAGAATCAACTGTGATTCCTGA
+
@@CFFFFFHHFHHIIIIIIIJJJIJJJJJJJJJJIJJGIJJIJJIJIIJJJIJJJJGGIJJHIGIIJHIJJIJJJEGIGIJJJJJHFHHGDFDCFFFFEE
@6NJ
GCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGC
+
;1=DBDDBFBFBHID=;?EC?A?;F;?CG@D?D9??09:9?D9?9BG8BDHDDA@F>@;@7..).=CE?A;?C;2,626>;;@B??:AC:C>5?5:::?B
@6NK
ATGCTTCCAAAGCTTTATGTGAAGCTAAATTACAGTGTGAGTTGTGCAATTAACAGCAAAGTAGTCAGGAATAGACCTCGTGAAGCCCGCAAGGACCCAAC
+
++:??<?A+A=A+++<>4,,3<?3++3+@AB><+1:*1117**:??**::**:0**)0/=A/0))/><A35.)/.)).)5(..1).(('333285;2(55(
@6NL
GCCAAGGGAAGGACGTCCTATGTACCAACGCCAGATGTCTGAGCCAAACATCCCCTTCCCACCACAAGGCTTTAAGCAGGAGTACCACGACCCAGTGTATG
+
@@CFFFFFHGHHHIIIJJJIIJHIGGIJIIJIIJIJGIIIJJIJJIJJIJJJJJJJIHHHHFFFFDDCDDDDDDDDCDDDDDDDDDDDDDBBDBDCC@CDD
@6NM
TGACTGGACAGTTACCTTATTCAAACATCAACAACAGGGACCAGATAATTTTTATGGTGGGACGAGGATACCTGTCTCCAGATCTCAGTAAGGTACGGAGT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJIIJJJJJJJJJJJJJJJJJGHJJJJJHHFFCEEEEEDDDDDDDDDDEDDDDEDDD@CDDDBD?
@6NN
TACTGGCCATTTGATCTATAAATGCGCTGGCATCGACAAAAGAACGATTGAAAGATTTGAGAAGGCTGATGTTGAGATGGGAATGGGATCCTTCTGGGAT
+
8;15(:(@)4)::)))2:=>>@>??2(54@(1)2(.-391(.7()-3=?;.8)).8))).:().(()((...(.(:(((-5((((((,,(+(++((((+(
@6NO
TGTGAACCTTATTGGGGAGCATTCTGATGCAGCAGAGCTTGGAAGGATGCTTCAGCTCATCTTAGGCTGTGCTGTGAACTGTGAACAGAAGCAAGAGTAC
+
@@@BDEEFGHHHHIGIJIJIJJIJIIIJJJIIJJJJJJJJJJIIJJJJJJJIIJIIGIIJIJJJIJDFCEHFFFCFFFEEEEEEEDDCDDDDDDC?BACD
@6NP
CCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJHHHHHHFFFFFDDDDBDDDDDDDDBDDDDDDDDDDDDDDDDD
@6NQ
ATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCC
+
@BBFFFFFHGHHHJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJIIJJJJJJJJJJJJJJJJIIJJJJHHHHHHFFFFFFEEEECDDDDDDDDDDDDDDDD
@6NR
CCTCCCTCCTCTTCCCAATACTATTCCCACTCCTCCAGATGCTCCAAATATCATGCACAAATGAGCAGGGCCGCGGTGGGAGTGGGCGCAGTGCGCTGCTG
+
CCCFFFFFHHGHHJJJJJIIJJJJJJJJJJJJJIJJJJJJJJIGJJJJJJIJIIJJEIIJJJIIJJJJJIJHFFDD=BDDDD<<BDBBBDD?CDDBDDDDD
@6NS
CAGAGAAGCTGCTCGAGAATGTCGCAGAAAGAAGAAAGAATATGTGAAATGCCTGGAAAACCGAGTTGCAGTCCTGGAAAATCAAAATAAAACTCTAAT
+
CCCFFFFFHGHHGJJJIJJJJIIIJJJJIJJJJJJJJJJJJJJJGIIJJJJJJJIJJJJJJJHHHDFFFEECEEEDDDDDDDDDDDDDDDDDDDDDDDE
@6NT
TACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCT
+
C@CFFFFFHHGHHJJJIIJJJJJJJIJJJJGJIIIIIJIJGJIIIG@EGIEHDHHHH@DFFFCEEEEECDCCDDDDCDCDCCDCDDDDDBDBDDDDBDDBD
@6NU
AAAAAGAGGAATCTCATTCTAATGATCAAAGTCCACAAATTCGAGCATCACCTTCTCCCCAGCCCTCTTCACAACCTCTCCAAATACACAGACAAACTCC
+
?;?DDA;DF8A>BBFBHBE<CBC??FE99EF?9CDGCDDGHG=?;?G@FFGDDHA>4CGH@5;;=CE7ACHEEABEEECCCCC;@C@ACCB?BBC?A>@A
@6NV
GCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCC
+
=@@D=>DDFHHHDBHHGIGFHBDGIGIIGEFFHEGGGIIIIGEECHIIIIGIEHHHEE@BB@DDDDCCECCDCAC>A>A@:?CDDDD@BACDDCB?BBBB
@6NW
AGGGAACTGGGTTCTGCCTTCTCTGGGCTGAGGTGTTCTGTTCTCTCCCGTTTGCCTCACGGCGTGCAGGAAGCGGGCAGATCCAGCTGTGGCAATTCCTC
+
@@@FDDDEDFFDFHIGGHIIEIIJJJICFGDGC??CFGIJJIJGFIIJGGHGIGIIIHIIIIBD=ADDEDDBD@BD@<<BDDDDDDCCCDCCBCCDD@CCC
@6NX
CAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCC
+
CCCFFFFFHGHGHIJJIJIJIIJIJJJJJIIJIJJJJJJICGHJJJJJJGJIJJJHHHFFBDFFEEEDDDDDDDDDDDDDDDDDDDDCDDDDDDDCDDDD
@6NY
GACCCTTCAAATTCTCATTTTATTGCCTGGACTGGTCGAGGCATGGAATTTAAACTGATTGAGCCTGAAGAGGTGGCCCGACGTTGGGGCATTCAGAAAA
+
CCCFFFFFHGHHHIJJJJJJJJJJGJJIJJJJJIIHIIJJJIIJJJJIIJJJJJJIIIJJGGIIIIIGHHHHF7@DEEDDDDDDDDDDDBBDDDEDDDDD
@6NZ
TTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGC
+
==<A<>@ABB>>@@A=A>@A37=C,?<7ACAC>?AAA7*:?>=?A<).<A=AAB98>ABA<AA;A(7=77>9?@>..;>5===(;;;=;;;?:9=99;;==
@6O0
CCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATG
+
@<@?DDDAD;CDFHABEHGIIEGEEEGGHHGGGCHGIDCCGFEHHE;?9DDFGF@BC4BA;AABHHBB;B7;AA>@@DCBBBBCBBCAABBB?B4>>:@CC
@6O1
GAAAGGACCTAAAGGTGTATATCAAATCAGCAAACAAATCAAAGCTCATGATGGCAGTGTGTTCACACTTTGTCAGATGAGAAATGGGATGTTATTAACTG
+
@<?DDDDDFDDBFBHHG?CH@HHEHIIGEE@EGGBGCGAHGGIGIIIIBF99DGEBDHE8BFHCF@FHGHIAHGIE>CHCCDEEEEECC6=;>BCCDE;@C
@6O2
ACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCT
+
CCCFFFFFHHGHHJIJJJJHJIJGHIJIGGIJJIIGGGIJJGIJJJGIEEHIHHIJJJJJJIJJIIFEHHFFBFFDEEDEEEDDDDDDDCDDCDDDDDDD?
@6O3
CAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACC
+
@@@FFADDHHGHGDBDDGHIDGGGIHGGFHIIIEHGIIGGHIIICEHIGIBA5CDHHIEHFEHEFBDEA;@CDDDD@B@CCCBA>AABCC@CCADDACCCC
@6O4
CACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATG
+
C@CFFDFFHHHHFIJJFGHJ?EGIIGIJJIIIIGJJADHGIJIIJIEGEHEHIJGIJJFHFFDCDDDDDDDDDDDDCDDDDDDCCCDDCBDDDDDDDCCCC
@6O5
CCTGTACACAGGCTTTTCCATCCTGGTGACTCTGCTCCTCGCTGGCCAGGCCACCACCGCCTACTTCCTGTACCAGCAGCAGGGCCGGCTGGACAAACTG
+
CCCFFFFFHGHHGJJJJJJJJJJJJJHIHIJJJJJJJJJJJJIJIJJJJJJJIJJJJJJIHHFFFFFEDECEEDDDDDDDDDDDDDDDDDDDBBDDDDDD
@6O6
ACAGTTGTCTGGATCCATTTTGTGGATGGCACCAGAAGTCATCAGAATGCAAGATAAAAATCCATACAGCTTTCAGTCAGATGTATATGCATTTGGAATTG
+
@@@DDFFDHHDDDGIGIJIJIJIEGHIIJJGHIIGIIJJIFGHIHGIIJGIHIIIIIGGJJIGEHCHHIJGGIJIHHHHGAHD;B;A@BA@AACEECDCD;
@6O7
GCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGC
+
CCCFFFFFHHHHHJJJJIJJIJJJJJJIJJJJIJJJJJIJIJJJJJJJJJHIJJJJJJIJJIJIIEHHHGGFFFFFFEEEECDDDDDDDDDDDDDDDDD
@6O8
GGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATG
+
CCCFFFFFHDHHHJJJIJJJIIJIIJJJJJJJJJJJJJIJJJJIIJJJJJJJJEHIIHHHHHGFFFFDEDEDDDDCDDDDDDDDCDDDDDDDDDDDDDDDD
@6O9
AAAAAAAAGAGGAATCTCATTCTAATGATCAAAGTCCACAAATTCGAGCATCACCTTCTCCCCAGCCCTCTTCACAACCTCTCCAAATACACAGACAAACT
+
CCCFFFDDHFHHHHGIJIJIJJJGHIJGGGIIJIHIIIIGIIJIJJJJIIGGIGIJIFEFHHFFDEDDDBDDDEDDDDBCCCCCDDCCDCDDCDCDDDDDC
@6OA
CTTTTTTCACCATTCTTCCACCCTGGAAACTCTATACACACACAGCCGGAGGTCATACTGCATCAGAACCATGAAGAAGATAACTGTGTCCAGAGGACCCC
+
CC@FFFFEFHGFHGHHIJGBEGIGGHGDGHIGIGG<BDCHHIGJ@FHA:;FEHEFH>EBCDDCD@CCCEDDDDCCDCDC:ACCCCCCD@CACC<AB@BABB
@6OB
CTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCT
+
@@@DA>DDHHFDHJJJJJIIJICCCEGHIGIGG<BBGIIEHGBFGHEHII=CEFEHGHHHHIHEHE@D?CEDD@AAC@>CDCCDDBBDBDDBBCCDDCCDD
@6OC
GGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACAC
+
=8;DDD?BFBFFDIF<3E?A@@ECGFE;<<CFEEDEI@FFFCFFCGAFB>?<BDFB8@=;=3@=EEIEFEE>?>B??B@CCCA?5@BAAA@D;;>A>::?
@6OD
CTGGAAGAAATGAGGGTTACCTATGGGACTGAAGGACTGCAGCAGTTACAAGAATTTGAAGCTGCCATTAAACAAAGAGATGGCATTATAACCCAGCTCAC
+
@CCFDEFFHHDHHJJICGHJJJJJJJGIGIJIJIJJJIIJJIIIJIIJIIJIIIJIIIGGIIIJJJJJJJHHEHGHFFFFEEEEEEDDEEEDDDDDDDDDD
@6OE
CTGTGGTGATGACATCTCCTGTGACTCTCACCTCTCAGACAACTAAGACAGATGACCCCCAATTGAAAAGAGAAATAAGGTTAATGAAAAACAGAGAAGCT
+
CCCFFFDFHHGHHJJJJJJJJJJJJJJJJJJJIJJJJJDGIJJJJJJIJIJIIJJIIJJJJJJJIGHJJHHHFHFFFFFECEEEDEDDDDDDDDDDDDDCD
@6OF
CTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGC
+
CCCFFFDFHHHHHJGIJJJJJJJJJJJJJJJGIJJJJJJJJJHIJJJIJJJJJJJJJJJJJGHHHHHHFFFFEDDEEDDDDDDEDEEDEDDDDDDDDDDD
@6OG
AGGGCCTGTCTCCTGCAACCCCTTTGAAACTTGATCCTCTAGGGCCCCTGGCCTCTGAGGTTTGCCAGCAGCCAGTGTACATTCCGAAGAAGGCAGCCTCC
+
@@@BDFBFDBFH?>CBFEEH<:FFHGGD9?EFG3CF<B@G@4?;B??@DGG>GIGG>@FHGEHGA?EH5;@DBC>CCD(5>CDACC@BB@(5?91<?B3<1
@6OH
CTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCT
+
@@@DDDDD:FFFFFFBEEFFIBEG;)::BDGF366(?=3=FDFACC@DE>C@ACEECEB??DBC9@BCA>A35@A@BBB@B@?@72<?BB?BB>(::@4>A
@6OI
ACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAAC
+
:@?DDDDDFHHDHGGF@EEGHIC>GGHBFGGHEF<DFDHIIHHGD?GDFDF49?FCD@F;766CBHHEBEEDDCA;6;;@35;;=>;;:ACCCCA@A?CCC
@6OJ
CTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTT
+
CCCFFFFFHHHGHIJJIIJIIJIJIJIJJJJJJJIJJJIJJJJJJJFJJJJJJJJJJJJGIHHHHHHFFFFFFDDDDDDDDDDDDDDDDCCDCEDDD9>5?
@6OK
GAAGGCTTCCTGGCTCATCCCAGCAGAACAGAAGGCTGTATGTTTGAAAAGGGCCCCAGGCAGTTTTATGATGACACCTGTGTTGTCCCAGAAAAATTCG
+
=?;:B?DBD<:++222C<<F;<3CG@+<E;GBE3)1?DD>9?0?F?*9DBFB1FBFF;(5((5.==?=BD;337).;,(.(--5,,:@>B35>A9<2::2
@6OL
CCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTAT
+
@@?DDDDBHBFHDDHHGGAGG@FBCFGGIIIIIIEHCC=DHIIIEGGGI@F=FGC@DHHAEAECEDBBECCBBBB?ACCCCCCA?BBBCB@CCCCCBB&9A
@6OM
GTAAAAATAGGTGATTTTGGTCTAGCTACAGAGAAATCTCGATGGAGTGGGTCCCATCAGTTTGAACAGTTGTCTGGATCCATTTTGTGGATGGCACC
+
CCCFFFFFHHHDFIJJJJJJHIJJJJJJJJJIJJJJJJJJJGIIJIJHHJJHIJJJJJJJJJJJIJJJJIIIHHHHHHFFFFFFEEEBEDDDDDDDDD
@6ON
GCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGG
+
CCCFFFFFGGHHHJJJIJJJJJJJJJJJJJJJIJIIJJJJJJJGIJJJJJHJJJJJJIHHHHHHFFFFFEDDDDDDDDDDDDDDDDDDDBDDDDDDDDDDD
@6OO
CAGGGACCCAGGCCGCACCAGGAGAACAACCACCAGGAGTCCTACCCTCTGTCAGTGTCTCCCATGGAGAATAATCACTGCCCAGCGTCCTCCGAGTCCC
+
CCCFFFFFHHHHGJIJJJJJJIJJJJJJJJJJJJJJJJJIIJJIJJJJJHGGHHHFFEFFFFEEEEEDDDDDDDEDDDDDDDDDDDDDDDDDDDBDBDDD
@6OP
CATTGCGCCTAGTGCCTATTACTGGGATAGGGATGAGAGAAAATAAGGGAGGTGTCCCCATGGAGGAGGTCGCTTGGGGTTGGAACGGTTTTTGTCGCGG
+
(---9)((00()))))..2=)2<8=((26)2():1):.000)09)):6((''(.).:)(.8<9=;(,('((,',,;;;'',&&((()&(+&(+)(()(56
@6OQ
CAACAGGGACCAGATAATTTTTATGGTGGGACGAGGATACCTGTCTCCAGATCTCAGTAAGGTACGGAGTAACTGTCCAAAAGCCATGAAGAGATTAATGG
+
CCCFFFFFHHHHHJJJJJJJJJIJJJHIJJIJIJJJIJJJJIJJJJJJJJJIJIJJJGGIHHCHHFFDD=AECDDCDDDDDDDDDDDDDDCCDDDDDDEDD
@6OR
CTTCTCTGCCACAAACTGTGGTGATGACATCTCCTGTGACTCTCACCTCTCAGACAACTAAGACAGATGACCCCCAATTGAAAAGAGAAATAAGGTTAATG
+
CCCFFFFFHHHHHJJJJJIJJGHJJJJJJJJJJJJJHIJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJHHFFFFEEEEEEDDDDDDDDDDACDDED
@6OS
GTTGGCAGTGCGGCCAGCCAAAGCTTTCCCCCTCCTCTGATGATTAAACAGGAACCCAGAGATTTTGCATATGACTCAGAAGTGCCTAGCTGCCACTCCAT
+
?@@DFFDBF?FFAGHGEGHIIAFGIFEDHEHIEHIIIGEDH@=CHCFHIGIICHGHEAE;=DFFCAECACCCD@CCCAC:AA5>@CCCCC:>AACCCCCCC
@6OT
GCCCATCAACCTCTCTCATCGGGAAGACCTGGCTTACATGAACCACATCATGGTCTCTGTCTCCCCGCCTGAAGAGCACGCCATGCCCATTGGGAGAAT
+
@@@FFFFFFDHHGJJJIIJJIJIGIJIIJGGHIJJJJJGGIIJJIJJGJJIJJBDFHIIIGGIJJEHFFBDEDEDDDAADDDDDDDDDDDDDDDABBDA
@6OU
CTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACC
+
CCCFFFFFHHHGHJJJJJJJJJJIJJJJJJJJIJJJJIJIGIIJJJJHJJIJJJIIJHHEFFFDDEEDDD5;>CDDDDDEDDDDDDDDDDDDDDDDDDCDC
@6OV
CTCAAAAGGAAAAACTCAAGGAAGAACTAGGACTAATTTTAGAAGAAAAGTGTGCTCTACAGAGACAGCTTGAAGACCTTGTTGAAGAATTGAGCTTTTC
+
?@@??DDDFFHFDBGH<FGEGCBFHGEFHIC@DFBGDDDDD:DFGIGGADGG8BFHGIEFHD@FHGGC9CDEFEH>@BDCBE@BCCCCCC@>CCCCCCC>
@6OW
GTCCAAAAGCCATGAAGAGATTAATGGCAGAGTGCCTCAAAAAGAAAAGAGATGAGAGACCACTCTTTCCCCAAATTCTCGCCTCTATTGAGCTGCTGGCC
+
?@@DFFDDHDHHDHBFGFHGGIIIEHIIIIIIHGEBGFEHGGCHDHIEGAFD8CCEGDGEEHGHGHHHHHHE=BDEE@;AACB??>>@AA>A>A>ACCCBB
@6OX
CAGATTTCGCCGCCAGCTTTCTGAACCCTGTAACTCCTTTCCTCCTTTGCCGACGATTCCAAGGGAAGGACGTCCTATGTACCAACGCCAGATGTCTGAGC
+
@@?;?BDD?CFHFEHIBHIGGGCFGEBADDGHHIDFGHGI><GHIIGIFGGF@GB4;6@DC>AC??B@@BB@;?@<CC<@BDCCC@05<<B@>>4:>@CCC
@6OY
TACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCT
+
@@@DDDDFHHFDDHJIGHIIIJIIIIIJJJDHEHGIICGFIIHGII@EHGGHHHGHHDFFFFEEECEECCDDBDDDDDDCDCCBCDDD@BBABDD?BDDDD
@6OZ
CGCAGATGCCGGCAATTATGCAAAAGCGTCACATGATGTAGGGACATGTGATATGTGCCTTGTTAAATAGAATATCTGATACCACCAAAGAATGAAACAGT
+
-((=->8<8.((((()2..))))2..9(<6(-)).)).)00)-7(7))..38)))))).)8.<=?>8))8).6===(98(6(:;55;78;<278((,++(+
@6P0
GTTCGACTGATGACTCTGAGGAGGAGCGAGCCCAGCGGCTGGCTGAGCTCCAGGAGCAGCTCAAAGCCGTGCACGAGCAGCTTGCAGCCCTCTCTCAGCCC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJIJJJJIJIJJIIJIJJJHHHHFFFFFEEDDDDDDDDDDDDDDD?BBDDDDDBBDBDDDDDDDDDDDCCDDACCDD
@6P1
GTGCAAGCCTATGTCCTATGAGGAGAAGCGGCAGCTCAGCTTGGACATCAACAAGCTCCCCGGCGAGAAGCTGGGCCGCGTGGTGCACATCATCCAGTCAC
+
CCCFFFFFHHHHHFEFHIIIJJIIIGIIIGGHEHIJJDGGIGFHBFHIGJIIJIHGDIEHHF>BB=BDDDCCCCB8AB@@>9B??CDCDDCACCDCC>CCD
@6P2
CTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGAC
+
CCCFFFFFHHHHHIJJJJJJIIIIJJJJJJJIJJJIJIIIIIJJJJJJJJJJJJJJIIHHHHHHFFFFDD@BDCDDDDDADDDDDDDCDDDDDDDDDDD
@6P3
CCTTATTGGGGAGCATTCTGATGCAGCAGAGCTTGGAAGGATGCTTCAGCTCATCTTAGGCTGTGCTGTGAACTGTGAACAGAAGCAAGAGTACATCCA
+
CCCFFFFDHHHFHJJIHIIJIJIJJJIJ<>FCHJGGIIIIGDFIDIGIEICGIIJJIIHIIGIDEHJGAHEAEBDEECDEE>CEEDCDDDD@CCCDDDD
@6P4
AGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAAC
+
CCCFFFFFHHHHGJJJJJJJJJJJJJJJJJJJJIJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJHHHHHHFFFFFFEEEEDEDDDDDDDDDDDDDDDDDD
@6P5
CCGAACTACACCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATGACATCTCCTGTGACTCTCACCTCTCAGACAACTAAGACAGATGACCCCCAATTG
+
CCCFFDFDHGFHHIJIHIGIJJJJJJJJJIGGGEGBHHFHB?BHFGGIGHHEHIIIGIHHIJEIEGHGCGHIGFHFEDCDDBCEEEECDCDCBBBBDDCC
@6P6
GAAAATGTACAGTCATGTGATACTCAAGTAAGCTCTTTATTAGATGGAGTTGTGACCATGACAAGCAGGGGTGCTGAAGGG
+
???:BDD?ADD?DEDID<C<4EDEFAC@ECE>DFACEC9???CFDDC3C0BD?D@DD<<?B3BD2(BCD;'-55?A?A@99
@6P7
GGACTGGGCTCCAGGGGCAACATTTCCCTGGGTCCTGGAGAAACCCTAGTACCTGGGGATACGGAGAGCAGTGTGATTCCCTGTGGAGGCACAGTTGCGGC
+
@@@BDF<DFFFHHGDCEEGGCHIGCGIGEHHI:BDDGC>23BFC@GH@CB=C@@DGEBHEEHCD?BCCC;55;>@:@ADDC@:A@?@22(<??C>CCC9>9
@6P8
ATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCT
+
CCCFFFFFHHHHHJJJJJJJJJJJJIIJJJJJJJJJJJJJJJIJJIJJJJJJJJJJJJJJIJJJJIJHHHHHFFFFFEEEDEDDDDDDDDDDDDEDDDDDD
@6P9
CCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGAC
+
CCCFFFFFGHHHHJJJJJJIJJJIJJJJJJJJJJJJJJJIJJIJIJJJHIHHIGIJJJJIJIJIJGHHHHFFFFFEEEDDDDBDBBD?BADDEEEEEADD
@6PA
CTCGCCTCTATTGAGCTGCTGGCCCGCTCATTGCCAAAAATTCACCGCAGTGCATCAGAACCCTCCTTGAATCGGGCTGGTTTCCAAACAGAGGATTTT
+
CCCFFFFFHGGHHIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJHHHHHHFFFFDDDEDDDDDDDDDDDDCDDDDEDDDDDDDDDDDDD
@6PB
GTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGC
+
CCCFFFFFHHHHHJJJJJJJJIJJJHIJJJJJJJJJJJJJJJJJJJJJJJJJHHHHHFEFFFFEEEEEEDEDDDDDDDACDDDDDDBBDDDDDDDDDDD
@6PC
CTCAGGTGGAGTCATGCTTATATGGAGCAAAACTACTGTAGAGCCCACACCTGGGAAAGGACCTAAAGGTGTATATCAAATCAGCAAACAAATCAAAGCTC
+
@@<?AD=ADFDFBHGIIEHIIECBHFC;FE@E3C?BFFHDFFACGGGCH7DHHIFCFGIA;FA=CEIFE)=ACCACFFEECCCCCCCC?BAB>:@@C@CC@
@6PD
TACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGG
+
CCCFFFFFHHHHHJJJJJIJJ@EGHJJIIIJJDGIIJJJJJIJJJJJJJJJJJIJJJJHIIJJJJHHHHFFFDDDEEDDDDDDEDDDDDDCDDDDDDDCDD
@6PE
AGTCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGC
+
@@@DDD??AAFF;EEBHIGB<FG:3CF>1CF@C*:?<:CBFHIBHH9?BD9?DD@C<FC:3=;C;6773?A=CCDDDD;;;A;>>9;=>B<?82<>BCCA
@6PF
TAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJIIJJJJJJJIJJJJJJJJJJJJJJJHHHHHFFFDFFEEEEEEEDDEDDDDDDDCDDDDDDDDDDDDDDDDDDDD
@6PG
CAGGAGATATGCAAACATATCAGATCCGAACTACACCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATGACATCTCCTGTGACTCTCACCTCTCAGAC
+
@@@BDDFFDHHHHEHIIGIAHIIGEIIDHGEGGIIIGIIIGHIGHIIFIIGGHIIEHIIIIGC@GG7CDEEFHFAHBDFBCA>CECC@ACCBABACCC@A
@6PH
GGATCACTTCAGCTCTGGCAGTTTTTGGTAGCTCTTCTGGATGACCCTTCAAATTCTCATTTTATTGCCTGGACTGGTCGAGGCATGGAATTTAAACTGAT
+
CCCFFFFFGHHHHJJJJJJJJHIJJJJJGIJJJJJJJJJJHJJJIJJJJJIJJJJIJJJJJJJJJJJIIIIJGJHHHHFFEDDDDDDDCDDDDDEDDDDCD
@6PI
GACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCC
+
@CCFFFDFHHHHHJJIIJGJJGIIIIIIIGGHIIIJGJIGIHGIJJIIJIDGFGHGHCDFFDDCCCEDEAADCCCDDDDBC??ACCDCD@?BDDACDDBD
@6PJ
GAAAAATAATAGCAGCAACAGCAATGTGAGCAAGAAGGAGCCAGCGCCCATGAAGAGCAAGCCCCCTCCCACGTATGAGTCGGAGGAAGAGGACAAGTGC
+
CCCFFFFFHHHFHJJJJJJJIJJIJJJJJJIIJJIIJJJIJJIJIJIIJIJJJJJJJJJJHHHHFFDDDDDDDACDDCDCCDB9>BDBBBDBDBCDDCCD
@6PK
CTTGGACCTTGCGGCGTCCACTCCATCTGACTCCCTGATTTATGACGACGGCCTCTCAGAGGAGGAGACACCGCTGGTGGACTGTAATAATGCCCCCCTCC
+
@@CDADEEHBFFHGIGFGIIIGGHGGEHGFGGGGGIIIIIIIIIIIIIHHFDDDBDDCDCCBBBDDD?@ACDDDBDD9AB<CCD@CDEECCDDDDDDD<>B
@6PL
CAGGAAATGGAGACAATCATTGAAGAATTAAACACTAAAATAATCGAAGAAGAAAAGAAAACTCTTGAGCTAAAGGATAAATTAACAACTGCTGATAAATT
+
;;;5(..)))68<5)).)).28)3)=>>;=@?3>1)2<=9.)):)(0:1=33>5)<7-.)<)...6=>)8:>;>;)9)).;.(39(6(3;(-:77((:0((
@6PM
GAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCGATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTG
+
???DD3BADDB>>D@E+A@FAEAE@@D??>9DEDD<DDDEECD'@=AA8@CDCEDCDDDCC@@AA@A;@?=?2>>(9=?=995>>4>AAA:<>3.<8<<:>
@6PN
CAGCAGATACTTGTGCCCAGCAATCAGGTGGTCGTACAAACTGCATCAGGAGATATGCAAACATATCAGATCCGAACTACACCTTCAGCTACTTCTCTGCC
+
BCCFFFFFHHHHHGGGIJJJJJIJJJIJHFGEHIDHIIJJJJJIJIJJIHHIIJIIJJJJJIJJJJJIJHHHHHFFDDCEEDDDDDDDDDDDDDDDDDDDD
@6PO
CCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATG
+
CCCFFFFFHHHHHGHIIIGIIJGIIGGJJGIHIJGIJJIJGEGGIIIJGIJGGGIIEIGEGGIHHHFFFFCDEDEEDEDDBDDDDDDDDDDDDDCDDCDDD
@6PP
TTATGATGACACCTGTGTTGTCCCAGAAAAATTCGATGGAGACATCAAACAAGAGCCAGGAATGTATCGGGAAGGACCCACATACCAACGGCGAGGATCAC
+
???DDFBDDF?FFGHCECGGFGHGBHEAHBGIIGEGHDAHC@?FFGC<?GGDD@@CCHGCGGFE=CHC;EEFD;=ACBBC?B>C><CCBB@7509@BCA8C
@6PQ
CTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJHHHHHFFDDDDDDEEEDDEDEDDDDDDDDDDDDD
@6PR
CGGCGGGGAAGATGTTCAGCGTAGAGTCGCTGGAGCGGGCGGAGCTGTGCGAGAGCCTCCTCACTTGGATCCAGACATTTAATGTGGATGCACCATGCC
+
@@@DDDDD?AB8=@CF@F9CE;D:57.;46'6?5=58=B03:-5&+3+937&&&08?9<@9<3<:A>C(:@C(::28:AD(>::4:C3(48(:?(4:3>
@6PS
CCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGT
+
@@@?DDDD?HD<AE?GBFGBCGFDDAFGEAGDDFEHI>FED;@4CF>@GAHIB.7A?>BEEC;@@CCCC??;?A>CCC@BB?1?<A>98A?9?>:A>A<A+
@6PT
AAATGCAAGTCTTTCTGGACAGCATCCTGCCTCCAAGTTGTCGAACAGAAAGGCCCTTGAGGCTGAATCGGCGGGGGGGGAAGTAACTTGGTGGCAGAGGT
+
0(0(-6))..)).266))).)-36);))).())()2.9))))((0(()0)..77=(()))))(.(6))).5/',5&&&0&&&(((((+((++(+(3((+((
@6PU
GGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTT
+
::12?2<<722<=C@=+2+3<<A@27A=C5@5ABABB?B?0?=0*0=?B>BB>;(=(87.88=36=;A>===;;);;555,555''82'(3:::+38=38
@6PV
CCCACCAGCAGAAGGTGAACTTTGTCCCTCCCCATCCATCCTCCATGCCTGTCACTTCCTCCAGCTTCTTTGGAGCCGCATCACAATACTGGACCTCCCCC
+
CC@FFFFFHHGHHIJFHIIJIJIIHGIGIIIJIJJJJJIJJJJJJIIIIIHHIIHHGHIJIIIJJFHHIJHHHHFFFFDDDDDCDDDDDDDDDDDDDDDD@
@6PW
CCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGT
+
??@DDDDADHHFHIIGGB?EHCCEEGGGIIHDCGGHBGIGGIIID>FGGGGCHGGIIGHHIIGGFHGDDCAABCCFECEEFCDCB=BB??B?BABBBBBA
@6PX
GGGAAAGCGAGAGGGAGACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGG
+
?@@DBDADDFDHFAHDGGIIIIG<?DHFE8?FHHH:AG5@E5=??;B;;?C@ACCA=@?@=<CBB7>>C@ACCDDDDDAC@ACDDDDDDC?AC>@B<9AAD
@6PY
GTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGC
+
@@@FFFFFHAHHHIIIGJIJIIIJIIIGFIIJJJJIIHHGIGIJIGIIIIJJHHHFFFFEEEEDEDDCCDEDDCDDDDBDDDDDDBDCCEDDDDDDDDDDD
@6PZ
ACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCT
+
?@@F?DFFHHGHHCHIIBEHDHIIIGII?FHHCGEGE?BFFGGFFFFA0?8BDDECHCHIGIIIIIHDEHGDEDD;;A@@CCDDDDADDCCBCCCDDCDB<
@6Q0
ATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCC
+
@@@FFFFFFFHHGGGHGIJJ@FHGGHIJHJCHIJGEGIIGIGGHIIIJJFEHCHHHHGBEFFDC@ADDCCC@CCDDCCCDAD:ACACCACCEDCDCCDD
@6Q1
GAACAAGAAACACAAAGAAAGTTAGAACAACTCCGGGCAGAGCTGGATGAGATGTATGGGCAGCAGATAGTGCAAATGAAACAAGAATTAATAAGACAAC
+
CCCFFFFFGHHGHJJJJIJJJIIJJJIJJIHIJJJJJJJIIJIJJJJIIIIGHICHIJJIJHHHFFFFFEADDEEEDDDDDDDDDDDDDCDDEDDDDDDD
@6Q2
CTCAAAGCCGTGCACGAGCAGCTTGCAGCCCTCTCTCAGCCCCAGCAGAACAAACCAAAGAAAAAGGAGAAAGACAAGAAGGAAAAGAAAAAAGAAAAGC
+
C@@FFFFFHHFHHJJJJJJJJJJJJJJJGIJJJGIICFGIJJJGIJJJIGIJJJHHHHFFDFFEEDDBBBDDDCCDDDDDDDBDDDDDDDDDDDBDDDCB
@6Q3
CCAAAAGTTACCAAAACTGCAGACAAGCATAAAGATGTCATCATCAACCAAGAAGGAGAATATATTAAAATGTTTATGCGCGGTCGGCCAATTACCATGTT
+
CCCFFFFFHHHHHJIJJJJJJJJJJIIJJIJIIJGGIIIJJIJJJJJJHIEHGHIJGIIJIJIJJIJJJJJJGIHGHHHFFDD>BBDDDDDDDDDDDDDEE
@6Q4
GTGAACCTTATTGGGGAGCATTCTGATGCAGCAGAGCTTGGAAGGATGCTTCAGCTCATCTTAGGCTGTGCTGTGAACTGTGAACAGAAGCAAGAGTACAT
+
;@?BABDDD:CFDBBEHEHFEDHHGEDFE@CED;;B?BGFB?FDCHIAHFGEH=FAHIC@@E;7==C>CA;A;CC>B?@;A@A@C@;ACCCCCA?<CCC>>
@6Q5
CACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGC
+
===A7=@A3<;?ABABBBBC>+<;;:AA;AB>ABB<3?A==>ABB947>AB=AAAAA)=;=ABB>>;7>A?>@;166;>>?>=3;?>3;;>5999588;
@6Q6
GCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATAC
+
@@CFFFFFFFHGGDBHIGEHHIIJJIJGIGIAHEEGHJJFEHIGGDCGBHGGGEIFEGFHHHHFDEDDC@@@CC@?BB3;>CCDDDDDDD?CDDCDCDEEC
@6Q7
AATCAATCTGATTCTATAGAAGACCCTAACAGTCCAGCAGGAAGAAGGCATTTGAAGCTCCAGACTCAATTAGAACAGCCCCAAGAAGAAAAATTCAGACT
+
<==AAAA7<,,22,<2=ACB=++3<?+?A;?=2?**1@AAAAAA3=A>==**99*0*8.7)9>A())77>>ABAB>A;;(,'5;5(5;=3;(99;:?>59>
@6Q8
TGAAAAGCCAAAATTTGTGCAGTGTTTAGCATTCTTGGGGAATGGAGATGTTCTTACTGGAGACTCAGGTGGAGTCATGCTTATATGGAGCAAAACTACTG
+
@@@FFDFDDHFFHIJJJFHJIJIIIIJJJIIJIGIGIJJGCHGIIIJGIJHIIIGGICGGIIGIIIIJI@EHEHHHFFFEFFCCE>CECDDDDDDDDDDDC
@6Q9
CAGCAGAAGGTGAACTTTGTCCCTCCCCATCCATCCTCCATGCCTGTCACTTCCTCCAGCTTCTTTGGAGCCGCATCACAATACTGGACCTCCCCCACGGG
+
?<?DFFDBFD<CHBEFFBHE@?FFBEB?EEHIIGEFDFHIEEFFFH??@@<FHGDHIIGIICCFIGGCHEGCEDFD9;ACAACCCDC:<C?CBBB9BBB9<
@6QA
ATTATCGAATACGTTGTGAAGACTTAGAAAAGGAGATCTCTGAACTTCGGCAACAGAATGATGAACTGACTACTTTGGCAGATGAAGCTCAGTCTCTGAA
+
-(0(=4337)9:1)8(:;>)91))2;))6=><5?17)9<>;)71:>8)93<5'3(.).)88:=8=830;))).;=;=3((7(6;:39((,;(,(:8:55(
@6QB
CGATCAGTAAGAATACAGAGCAACGGCCCCAGCCAGATCCGTATCAGATCCTGGGCCCGACCAGCAGTCGCCTAGCCAACCCTGGAAGCGGGCAGATCC
+
CCCFFFFFHHHHHJJJJJJJJJJJIJJJJJJ?FHJJIJJJJGIJJJJJJJJIFHIHHGFFDDDDBDDDDBDDDDDDDDDDDDDDDDDDBBDDDDBDDDD
@6QC
GGATGCTTCAGCTCATCTTAGGCTGTGCTGTGAACTGTGAACAGAAGCAAGAGTACATCCAAGCCATTATGATGATGGAGGAATCTGTTCAACATGTTGTC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJIJJJJJJJGIIIJIJJJJJJJJJJHHJJJJJJJJIJJJJJJIIIJFIIIFHHFFFFFFEEDEEDEDDEEDDD
@6QD
TTTGGAAATTTCAAAGCTAAAAGATTTACAGCAGTCTCTTGTAAATTCAAAGTCAGAAGAAATGACTCTTCAAATCAATGAACTTCAAAAAGAAATTGAA
+
?;;B;DDFDBHDCFEIBCHEGGDHGGGGHIIIGGFHEEEFDGEGCBF@DHIIFE@FGEGAHGHIHIDHHIIIIIGIIIEDCHEEEFEEEFFF?ACEE>@A
@6QE
TTGATAACTAAGCAGAATCAATTAATTTTGGAAATTTCAAAGCTAAAAGATTTACAGCAGTCTCTTGTAAATTCAAAGTCAGAAGAAATGACTCTTCAAAT
+
CCCFFFFFHHHHHJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJIIJJJJJJIIJJJJJJJJJHJJHHHHHFFFEFFEEEEEEDDD
@6QF
TGGCATTAGTTCTGTGTGCTATTGGTGTTTATTTGCATCCACCTGTCCAGTTGCTCTGCTGTCTTGTGTTTTTGCAGCCTCTACAACCCCACGTCAGAGTG
+
<@@DADDFHDDHHGEHCFIIGGHHIBGCGGIIFGIGIIIIIIIIIHIGGEADHGGIEIICHGHHEHFH@CFGGGEGHGHHHFFFFFECCCCBCCBBBCC:A
@6QG
TACCAACGCCAGATGTCTGAGCCAAACATCCCCTTCCCACCACAAGGCTTTAAGCAGGAGTACCACGACCCAGTGTATGAACACAACACCATGGTTGGC
+
@;;BDDDDDDDDHBFHH4AEFHGGFH8FG3CD7>@:?0BB@DBFGB2BBG@FEG:=7@@=)77CC;=8>BBB=(,((((,>::(9?<@B?BAACA@05:
@6QH
CCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJHHHHHFFFFDDEEDDDDDDDCDEDDDDDDDDDDDDDDDDDDDDD9@
@6QI
CTCAGCCCCAGCAGAACAAACCAAAGAAAAAGGAGAAAGACAAGAAGGAAAAGAAAAAAGAAAAGCACAAAAGGAAAGAGGAAGTGGAAGAGAATAAAAA
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJIJJJJJJJJJHFFFDEEEEDDDDDDDDDDDDDDDDDCCDDDDDDDDDDDDDD
@6QJ
GAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTC
+
CCCFFFFFHGGHHJJJJJJJJIIJJJJJJJIJJJIJJJIJJIJJJJJJJIJJJJJIJIJJJJJJJJJHHHHHHFFFDDDDBDDDDDDDCDDDDDDDDDDDD
@6QK
AAAAATAATAGAAGAAGAAAAGAAAACTCTTGAGCTAAAGGATAAATTAACAACTGCTGATAAATTACTAGGAGAATTACAAGAACAGATTGTGCAAA
+
:=;D?DDFAHHFFCGIBHGIIHGHG;D>FHGGHFCDFHBGIIGEHIIIBHGFEHIFGGIE<FGEGHI@@F;77CCEFEH7AADCFDE;@CCCCC:@>@
@6QL
AGTAGGATGCCTGGATTTTTCAAAAGCAGATTCAGGTGTTCATTTATGTGTTATTGATGACTCCAATGAGCATATGCTTACTGTATGGGACTGGCAGAGG
+
@@?DDFFFBFFHHDD9EDEHCHIICFHI@CDFEHGG4?C?@@DGHGIG*?BGHECH?BDEG>HCHEGIGFCGFH>EBHEHCHFEE>HFDFF9A?9A??BB
@6QM
GATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCC
+
@@@?BDA?DFF<DC@FFBGECGFGHC>GE;FGCG>FHFECHI<A><3=F=<FCFHBG97DAHEHEFEEED;7@DACCCC;?>?@?>>A@@@CBB@B@BCCB
@6QN
AGAAAAGGAAACCTCAAGCTGAGAAAGTTGATGTGATTGCCGGCTCCTCCAAGATGAAGGGCTTCTCGTCCTCAGAGTCGGAGAGCTCCAGTGAGTCCAGC
+
C@CFFFFFFGHFHJJJJJGIJIJJJJJHHIHGIDFEIIIIIGIIGGIHIJJGEHGIIHEIIFFHHHGFFFDDCCDDD>@@BDD?BDCDDAC>CCDCCDDDD
@6QO
AACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJHIJJJJJJJFHIJJJJJIJJJJJHHHHHFFFFEDEDDDDDDDDDDCDEDDDDDDDDDDDDDDD
@6QP
AAAGTTCACTGCTGGCCTATAATACAACCTCCCACACCGACCAATCCTCACGATTGAGTGTCAAAGAAGGTCCTCCCCTTGGAGGGGCACAAACGATCAGT
+
@@@DDDDDB:=:<<CFFFF<<?ABA4+C@FF@@;C@FB?F:DFFCB;=FFIE;@A;=C=>AC;=BD;?;>.;@;AB??5=9?A<??-5&8??8@93?BBB4
@6QQ
CAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTT
+
CCCFFFFFHHHHHIIJJJJIGIIJJJJIJJIIJIGIJJJJJIJJIIJJJJJJGIHHIJJIJJHHHHHHFFFEFEEEDEDDDDDDDBBDDDDDDDDDDDDDE
@6QR
CAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGG
+
B@CFDFFFHHHHHJJJJJJJHIJIJJIJJJJIIJJJJJJJJJJJJJJJJIICFHIJJJGIJJHEHHFFFFFEEEEEEDEDDDDD@BBDDDDDCDDDDDDDD
@6QS
TCCTCATTGAGGTGATGTGCTCTATGAACTCCTTCAGCATATTCTGAAGCAGAGGAAACCTCGGATTCTTTTTTCACCATTCTTCCACCCTGGAAACTCT
+
@CCFFFFFGHFHFHHGHEIIGIJJIGJJIGIJJJIIIIJIJJJJJJIGGJJGIIGEGIGIIJGJAHHHHIJJJHFFFFFCDDEDEDEDDDDDDDDDDDDD
@6QT
GAACCCCCGGCACTCCGTGGATTTCAAACAGTCCAGGCTCTCCGAGGACGGGCTGCATAGGGAAGGGAAGCCCATCAACCTCTCTCATCGGGAAGACCTGG
+
???ADDAD8?DDA9?EBDDD1?DD@D*?BDDBDE@*)88(8A@AA4'-;??/3>;=A>555=A<<8-(+<22<839:A<<(9:>4>AD>A??>>8893>>?
@6QU
CGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTT
+
CCCFFFFFHHHHHJJJJJJJIJJJHJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJHHHHFFFFFEEDEEDDDDCDDDDDDD@BDDDDDDDDDACDDD
@6QV
GGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJIJJJJJJJJJJJJJIJJJIJJJHGHFFDDEEEEEDDEDEDDDDDDDDDDDDDD
@6QW
CCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTA
+
CCCFFFFFHHHHHJJJGIJJJJJJJJJJJJJJJJIJJJJJJIIJIJJIIJJIJJJJJJJHHHHFD?BDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDAC
@6QX
TGGAGAATAATCACTGCCCAGCGTCCTCCGAGTCCCACCCGAAGCCATCCAGCCCCCGGCAGGAGAGCACACGCGTGATCCAGCTGATGCCCAGCCCCATC
+
@C@DFFFFHHHGHJJJJIJIIJJJJIJIJJGEFGIJJJJJIIJGIJJJJJIJJFHHFCDDDDDDDABDDDCDBBD<BBDDDCDCCDDDDDDDCDDDDDDDC
@6QY
CACTCATCAACAGCAGCTTGAAGAACAAGACCACTTATTAGAAGATTATCAGAAAAAGAAAGAAGACTTCACAATGCAAATTAGTTTCTTGCAAGAGAAA
+
CCCFFFFFHGHHHJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJHHHHHHFFFFFFECEEEECCCDDDDDDDD
@6QZ
CTCAACCCCTGTTTTCCCCTGCCTTCCTTGCAGAGGCCATGGAGGACGAGGAGAGACAGAAGAAGCTGGAGGCCGGCAAAGCCAAGCTTGCCCAGTTTCG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJIJJJJJJJIHHHHFFFFFEEEEEEDDDDDDDDDDDDDDDDDDDDCDDDDDDDEED
@6R0
CCTTGAATCGGGCTGGTTTCCAAACAGAGGATTTTAGTCTATATGCTTGTGCTTCTCCAAAAACACCCATCCAGGCAGGGGGATATGGTGCGTTTCCTGTC
+
@@@FFFDDFHHDDEGG<ABHEHIIGIGIGGDEGEFBGBGHBGEGGDDHHDDDGHEGEHIIIGCHHHHEEDC;@>@=?ABDDD99CCCDAA@>BBBCDDD:A
@6R1
CTGTCACAGAGACTGTCTGATCTTTCTGAACAATTGAAACAGAAACATGGTGAGATTAGTTTTCTAAATGAAGAAGTTAAATCTTTAAAGCAAGAGAA
+
@C@FFFFFHHGHFJIIJJJIHGIJJGIHIIIIJIJIIIGIIIJJGG@FHEFHGGCGHDIHIIIIIGIIIIGIDIJJIIIJFHHHHHGFFFFFFECECD
@6R2
GCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCT
+
@@;DDB?==DBA?E::?AF;FAGAGG<9?CGF?9*:::9:9B?8:))?F?F8DFEFEGGC3C3C@;@;A;55?B<?BBBA53>55>,5::AA>A>B@??BB
@6R3
GTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCC
+
CCCFFFFFHHHHHJJIJJJJJJJJIJJJJJJJJJJIJIJJJJJJIJJJJJJJJJJIJJJHHHHHHFFFFFDDEDDDDDDDCDDDEDEDDDDDDDDDDDDDD
@6R4
GGAAAGTGAGTTGGCTGGGAAGCAGCATGAGATTGAAGAGCTAAACAGAGAGCTGGAAGAAATGAGGGTTACCTATGGGACTGAAGGACTGCAGCAGTTAC
+
CCCFFFDDFHHHGGJJJJJJJJIJJJIJJIJHGJJJJIJJIJJJJGHEEIIIIJJIIIJJJJGGIJJJHHHHFFFFFFDEEEDDCDDDDDBDDDDDDCDDC
@6R5
CAGGTTTGTCTGCTACCCCCCCTGCCTCATTACCTGGCTCACTAACTAACGTGAAAGCCTTACAGAAATCTCCAGGACCTCAGCGAGAAAGGAAGTCATCT
+
?@@?=ADDDDFHDHIGHGDHGA@FGIHFGGIEIEBDFEEHIIGGGGIIGCE766;=;;BB@;A;AC@@;@5>5;A<AB?CCCCCB>B@BCCBCCBCC@CAC
@6R6
GGACGTTTATGAGAACTTCCGTCAGTGGCAGCGTTACAAAGCCTTGGCCCGGAGGCACCTATCCCAGAGTCCTGACACAGAAGCTCTTTCCTGTTTTCTT
+
+=+2202?A?B?BB7A>ABAA@;2?27;):)::)0?57<*:0>A***9=;<65=A=@@=(.65>3;;(;((,,;;9;:=;(883(+33::=:358=<?::
@6R7
CTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTT
+
CCCFFFFFGHHHHJJJJJJJHHJJJJJJJJJJJJJJIJJJJJJJJJIJJJJJJJJJIIJJJJJIHHFFDEEDEDDDDDDDDDDDDDDBDDDDDDDDDDDCD
@6R8
CCACAAAGCCACAACTGGCTATTGTTACCCAGTGGTGTGAGGGCTCCAGCTTGTATCACCATCTCCATATCATTGAGACCAAATTTGAGATGATCAAACTT
+
C@@FFFFBFFFAFIIIIGFHDGHEIIGBHIGIGHFIIGGDFHIIIGIIIIIIIIIIIIIIEHECHHBEHHEHHF>B>?DCCDDDDCDDBBDDCDCDDDDDD
@6R9
CAGCCACGCCAGGCCAAGGGTGAGCTGGGGCTCTCCCAAATGCTCCACATTGCCAGTCAGATCGCCTCGGGTATGGTGTACCTGGCCTCCCAGCACTTTGT
+
:??=:BADF?FFF@?EGFC@8CGFFF@?DFBFGBE@FDFFF=@8CCAFAECD9=C=.=EEFFDDDD<>>B?=?@A?B:55;AB:@B8@888?A8<@BA@A:
@6RA
CTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCT
+
=??DDDDDF;FDHGIIGIIGGIEGIICGGEGIG?FDHCGEBGBDGGGIIEGGEAFG;4=D@@3=?;;BB@C@ACBBCCCEDA>CC@=BB<@@BACCCCCCC
@6RB
GGAACCCAGAGATTTTGCATATGACTCAGAAGTGCCTAGCTGCCACTCCATTTATATGAGGCAAGAAGGCTTCCTGGCTCATCCCAGCAGAACAGAAGGCT
+
?+1ADDDDDFFDFFFFIB<CHDCE?CFBEHEB*?EB<C?@FGEIFIGFIIIIIEGFIDBFEEIFIIFA;EFCFEEFDDDDDDDCC@AA?B@BBB9?@BB?B
@6RC
GCAAGAAGGAGCCAGCGCCCATGAAGAGCAAGCCCCCTCCCACGTATGAGTCGGAGGAAGAGGACAAGTGCAAGCCTATGTCCTATGAGGAGAAGCGGC
+
CCCFFFFFHHGHHJJJGIJJJJJJJJJJJJJJJJJJJJJJJJJJFHIJIIJHHHDEDBDDDDDBDDDD@CDDDDDDDCDDDEEDDDDDDDCBDDDDDDB
@6RD
ACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACT
+
CC@FFDFDDAD1?FHBB@FAHHICFDGAGDHB?B9DEGDFGCEGHIGGIIDGII<>HHCCHC33?CCCCB<9<B?8ABB?A<?ACC@C>4:>?9C(>@AD
@6RE
AAGGAGCACAAGACAGTCCGACTCATCTAGAGATGATGGAAAGTGAGTTGGCTGGGAAGCAGCATGAGATTGAAGAGCTAAACAGAGAGCTGGAAGAAATG
+
;<;+=;DDBBDD:C?C<EF=F@E@9B?EDD<?4?D>@?0?3DD*9?D98?B=<BADDIDIEDI@>=;A3;7;;;@@AAA@A;>3;>>35,5><?5:<A?:>
@6RF
ACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJHIJJJIJJJJIJJIJJJJJJJJJJJJJJJJJJJJJJJJJHHHHFFDDDDDDDDDDDDCDDDDDDDDDDDDD
@6RG
CGACGAGATTGAAATCGACTTTGAGACCCTGAAGCCGTCCACACTGCGTGAGCTGGAGCGCTATGTCACCTCCTGTTTGCGGAAGAAAAGGAAACCTCA
+
@@@BDDFAFHHBFHEGBHHIIGIGGIIDHIGJG@FHBFHGEGEFG;CF;BGHEEHHDFB>BD@DDCD>CC@ABCD:@ACDBD5<<<CCDDD@DCABACC
@6RH
CAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGC
+
CCCFFFFFFHHHHJJJIJJJJIJJJHICEHGICDGHHG?FHIJIIGJIIJIJIIGIGJJJGIIHHIHHHHGFFFFDDCDDDCBDDDDDDEDDDDDDCCDCD
@6RI
CAAGCCTTCAAAAATGAAGTAGGAGTACTCAGGAAAACACGACATGTGAATATCCTACTCTTCATGGGCTATTCCACAAAG
+
@CCFFFFFHHHHHJJJJJJHIIJJJIIJJJJJJJJJJIJJJJJJJJIIIJJIJJJJJJJJJJJJIJJJJHHHHHHFFFFFE
@6RJ
GTGCACCATAACCCTCCCACCATTGAACTGTTGCACCGCTCCAGGTCACCTATCACGACAAATCACCGGCCTTCTCCTGACCCCGAGCAGCGGCCCCTCCG
+
@@@DFDFFHGFFFIGAHIGEDGCCCHHHGFFGHHCGEHE?FEDGGECH>BFGACEGHIGHHHDECD@BDD@BDCCC@@@CCCDDDB5<BC?B<@BBDB9B>
@6RK
ATTTATATGAGGCAAGAAGGCTTCCTGGCTCATCCCAGCAGAACAGAAGGCTGTATGTTTGAAAAGGGCCCCAGGCAGTTTTATGATGACACCTGTGTTGT
+
@@@FFFFDHAFHHEGGBGGHAGGGIBHIGIEHEHGGGH>FHGDAFHIIIIICG@BAD@AAG>C@@CGIFHHEFDC=AB=AD@@@CA>ACACCCCC@A:?AA
@6RL
GGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTT
+
CCCFFFFFHHHHHJJJJIJJJJJJIJJJJJJJJJJJJJJJGIJJIJJJJJJJJIJJGIJJJIJJJJJHHHHHFFFFFFEDDDDDDDDDDDDDECDDDDDD
@6RM
TGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGAC
+
CCCFFFFFHHHGGJJJJIJJJJIJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJGGGHHHFFFDD?BDDDDCDDDDDDDDBDDDDDDDDDDDDD
@6RN
TTACAAGCCTTCAAAAATGAAGTAGGAGTACTCAGGAAAACACGACATGTGAATATCCTACTCTTCATGGGCTATTCCACAAAGCCACAACTGGCTATTGT
+
CCCFFFDFHHFHHJIJIIIJJJHHIIJJIHHIIIIJJJGHIIJJIIIGHIIIIEHGIIEHIJJJIGIDCHHHGHEDFFFCEDECCBCDDDBDDDDDDDDDE
@6RO
CACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGC
+
@<@DD?A=AFFF?::ACGG>:A;8CCHHI93?BFECFGH@?;D?D<BB<;2B6C@G@@EE=@A4AA?AEACED(;=;>A;--;?=:,:A:5<(:A3A(8
@6RP
TACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGG
+
@@@DFFFFHHHHHGJJJIIJJIJGIIJJJIJJJIJIJJJIJJIJIJJJFIIIJIIJIJJIJJGHIJJHHGHFFFFFFEEEDDDDBBB
@6RQ
GTCCATAGGTTCCATAGCTTTGTTGCCCATATGCCTGGGTGGTCTGTGCATATCCTTGAGTGGGCTGGGCGGTGTAAGCACTGTAGCCCTGCTGCGCTGC
+
@C@DFFFFHFHFFHIIJJIIIJIGIJIJJIGIEAFGIIJDGA6BGGBF@HGIJIJIJGJDBFHGAEHHHEHD3;8@ACCDCDD>CD@@ACAB@@A>BDDB
@6RR
CCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGAC
+
CCCFFFFFHHHHHJJIIIJJJJJJJJJJJJJJJJJJJJJJJIIIJJJIIJGIJJJJJJJJJJJJJHHHHHFFFFFEEEDDDDDDDDDDDDDCDEEEEDDD
@6RS
CTGGATGACCCTTCAAATTCTCATTTTATTGCCTGGACTGGTCGAGGCATGGAATTTAAACTGATTGAGCCTGAAGAGGTGGCCCGAGGTTGGGGCATTC
+
??@DD>DBAD:C:C@:?EADHH9CH@:CH9HF@FFICD9F?:BDFEGE=3BA3=BFFIIA@C:74=ECE@EF@9@B7>@(=?;;;?;'3)+9@@B55<>>
@6RT
CGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTT
+
@@@DFDDF?FD>FHGEDGGGBHIIGIIIIIGBHHGGHGIIGGHIIHIIEHIGFGHIGHGHHGGDDDFFDDDEEDDDBDCDCCDDB?@CCDBCDDDD><C@C
@6RU
CCTGGGGCTGGAGGGAAGCTGTACTGTCCCACCTAACGTTGCAACTGGGAGACTTCCGGGGGCCTCACTGCTCCTAGAGCCCTCTTCGCTGACTGCCAAT
+
CCCFFFFFHHHHHJJEHGGIIIIJJJJJJJJJJJJJJIIJIJJJJIJJJIJGIJJIJHHFDDDDDDDBDDCCDDDDDDDDBDDDCDCDB<@BDCDDDDDD
@6RV
GAAAGAGGAAGTGGAAGAGAATAAAAAAAGCAAAGCCAAGGAACCTCCTCCTAAAAAGACGAAGAAAAATAATAGCAGCAACAGCAATGTGAGCAAGAAGG
+
@@@DD;DDFDDFFHGFHECEHIGGAEGGIICHIFIIJIIIJIJIGGJI@HJDHHIIHHEHE<ADBDDDBBCDCDCDDC?BDB?BD?CAC@D>CA:?A9?CB
@6RW
TGTTGGCAGAGAATCAGGTATTAATGGAAAGACTCAATCAATCTGATTCTATAGAAGACCCTAACAGTCCAGCAGGAAGAAGGCATTTGCAGCTCCAGACT
+
?@=BDDDDHBDFDHIIGI3AFFHHGEFEGGGAEGDHIIEGCAGGHFGEGIA?FABGD@FEHGHFGIIHIIB=DEAHEEEECDBCCCCC@CD>;;-;5::<5
@6RX
CGGGAAGGACCCACATACCAACGGCGAGGATCACTTCAGCTCTGGCAGTTTTTGGTAGCTCTTCTGGATGACCCTTCAAATTCTCATTTTATTGCCTGGAC
+
@CCFDFFFHHHHHJIIJJJIJJJIFIIIIJJJJIJJJGIJJJIHHHHFEEFEFAB;@CDDDDDDDDCCDCCDDDDDCDDDDDCDADEEEEEDDDCDDCDAB
@6RY
GTGAAATGCCTTGCTATACATCCTGACAAAATTAGGATTGCAACTGGACAGATAGCTGGCGTGGATAAAGATGGAAGGCCTCTACAACCCCACGTCAGAGT
+
@B@DFFEDFFHGHGGJJJJIJIIJIIIIJIIGGIIIHIJJJIJJJIJGGIGJJJIIIIIJIHIIGHGIHHEHHHFFFFDDDEECDCCCDDDBDDABDDCDC
@6RZ
TGAGAACAGGAAAGCCTACAAATTTATTAAGGGAAGAAGAATTTGGTGTTGATGATTCTTATTCTGAACAAGGAGCACAAGACAGTCCGACTCATCTAG
+
@@@DDDDDBFFFDI>FF<<AA:CHF?CBBHHIFBBCGIEBD@FFGI?BGEF@BB<=CBBFCCF@@@FFFIIIA6AA?BDDD>@@@@AB?BB;=:@A>::
@6S0
GCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGT
+
CCCFFFFFHHHGHJJJHJIJJIJJJHHJJJJJJJJJJIJIJJJJJJJIIIIIJJJJJJJJJJJJJIIIGHHFFDEDEEDDDDDDDDDDDDDDDDDDDDDDA
@6S1
GTCGTACAAACTGCATCAGGAGATATGCAAACATATCAGATCCGAACTACACCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATGACATCTCCTGTGAC
+
CCCFFFFFHGHHHIJJJJIIIIIHIIIJIJJIIJJIJIJJGIJJGIIIJJJJIIGIGHJIJIIIGGIJIJHGFGFFFFFECE;?CDDEDDDDCCCCDDDED
@6S2
TGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTT
+
?@@=;DDDFHFHFIIGGBGG?FBEHEEIIIEB?@FDHIG>D???DFGEB?BFGGGI=G@GI7@@AGIF>7=CD?CDEC@AACB@B?BBBBCCCECC?ACCA
@6S3
CTCACCTCTCAGACAACTAAGACAGATGACCCCCAATTGAAAAGAGAAATAAGGTTAATGAAAAACAGAGAAGCTGCTCGAGAATGTCGCAGAAAGAAGA
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHIIJJJJJJJFHIJJIJJJJJJJHHHHFFFFFFEEDDDDDDDCEDDDDDDDDDDDD
@6S4
TGAAGCCGTCCACACTGCGTGAGCTGGAGCGCTATGTCACCTCCTGTTTGCGGAAGAAAAGGAAACCTCAAGCTGAGAAAGTTGATGTGATTGCCGGCTCC
+
==;A7+A=A)77A9+2<@A0=?ABAA9A5)?)=4:AABB<8>>A;>8=A=)5/',9(6>>>55;(;==(;555;::((8;:5(+8:8+33++(8350.008
@6S5
CCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJIIJJJJJJJJJJJJIJJJJJJHHHHHFFFFFFDEEEEEDDCDDDDDDDDDDDEDDDDBDDDDDDDDDDDDDDDD
@6S6
ATTTCCCTGGGTCCTGGAGAAACCCTAGTACCTGGGGATACGGAGAGCAGTGTGATTCCCTGTGGAGGCACAGTTGCGGCAGCTGCCCTAGAAAAGAGAA
+
CCCFFFFFGGHHHIJIIIEIIGJJIGJJFIGIIJJIJGIIJJIBHHIIIIGECFHJIJJIJJAHFHHFFFFEECEEDDDDDDBCDDDDCCDDDDDD<CCD
@6S7
GTTCAAGATCGCCTGTCAGCTCTTGAGTCACGAGTTCAGCAAGAAGATGAAATCACTGTGCTAAAGGCGGCTTTGGCTGATGTTTTGAGGCGTCTTGCAAT
+
@@@BDDAD<CFHH:FHIG?A@CDGGIGCHHIECGDDBGIGIIGIGGIIIIIC@<=CHCCGGCEFGGGCA<B@BA:A>C?9::5>@?B??CB>5>@B:@ACC
@6S8
GGGAGACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTT
+
CCCFFFFFHHHHGIJJJJJJIIHGHIFHJHIJJIIIJJIJIJIJJHHHFFFDDDDDDDDDEEDDDDDDCDDDDBDDDDDDDDBDDDDBDDDDDDDDCCDED
@6S9
GTGAACTGTGAACAGAAGCAAGAGTACATCCAAGCCATTATGATGATGGAGGAATCTGTTCAACATGTTGTCATGACAGCCATTCAAGAGCTGATGAGTA
+
CCCFFFFFHHGGHJJJJJJJJJJJJJJJJJJJJJJJJJJJJIIJIIJJJJJJJJIJJJIJJJJJJJJIIIIJIJIJIHHHHFFFFFFFEEEEECDDEDCD
@6SA
TATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTT
+
CCCFFFFFGHHHHJJJJIJIJJJJJJJJJJJJJJJIJJJJJJJJIJIJJJJJJJJJJJJEHHJHHFFDEEEEEDDDDDDDDDDDDDDDDDDDDDDDCDCD
@6SB
GGAAGAAATTGCTCAAAGATTCCATGAACTGGATATGCAGGTTGCAGCATTGAAGGAAGAGAAAAGAAGTTTGTTGGCAGAGAATCAGGTATTAATGGAA
+
7((((2)))=?<1;.6=<<=))3@=1)=)8=9.)6<;>8?7=1<(6)=7<;))>=>(.;(66:9)<(().8)).877).59():938(6--(--(9=<;;
@6SC
TTTCAAACAGTCCAGGCTCTCCGAGGACGGGCTGCATAGGGAAGGGAAGCCCATCAACCTCTCTCATCGGGAAGACCTGGCTTACATGAACCACATCATGG
+
CCCFFFFFHHHHHJJJIGHIJJJJIIJJIJJJJJJJJJJJJIJIJJJJHHHFFFFFEEEEEDDDDDEDDDDDDDDDDDDDDDDDDDEDDDDDDDDDDDDDD
@6SD
CTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJIJJJJJJJJJJIJJJJJJJJIJJJJJJJJJJJJJJJJJHHHHHHFFFFDEDDDDDDDDDDDDDDDDDDDDDC
@6SE
GGGAAGGACCCACATACCAACGGCGAGGATCACTTCAGCTCTGGCAGTTTTTGGTAGCTCTTCTGGATGACCCTTCAAATTCTCATTTTATTGCCTGGACT
+
@@@DD?ADFFDFBGB<CF@?FCEBFBGGGHGI=AFGEHECDGDG@HEHHEEEBA?ACA;;AC;CC>5>ACCCBCCCCC@>>>@3:4>DCBCC>CCCAB@BC
@6SF
TGCTTTTTCGCCTTGCTACACATTCTGACAAAATTAGGATTGCAACTGGACAGATAACTGTCGTGGATAGAGATGAAAGGCCTCTACAACCCCACGTCTG
+
-7131)9;)0-:084<6));)48)..;)6)))1):):::9:)97):>)).336=?>)).6.)--';3;.).).;))...63698(:9-((3'','06((2
@6SG
GTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAAC
+
@@@FFFFFH>AFFGIIJIIGIGGFCHIJHDIGIGBGGIIJIHCIGGFFGGIIAHBAAHIJIIIGHCEHBEEE@DDEECDCA>CCDCCDDDACCCDCCDD
@6SH
TAGCATTCTTAAAGATGAAAAGAAAACCCTTGAAGACATGTTGAAAATACATACTCCTGTTAGCCAAGAAGAAAGATTGATTTTCTTAGACTCCATTAAGT
+
CCCFFFFFHFHGDGGHIIIJIIJIGGJJJJJIIJIDIJJEIIJJJJJJJJIJIJIIJIJFFFHJJJIIIGIJIJJHHHHHFDFFFFFEEEDEDDDDEDDD>
@6SI
GCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJIJJJJJJJJJJIJJJJJJJJJCGGGJJJJJJJJJJJJHHHHHHHFFFFFEEEEEEEDDDDDDDCDDDDDDDCDD
@6SJ
CACCCTCATTCGGGGTCTGGGCCATGGCGCCTTTGGGGAGGTGTATGAAGGCCAGGTGTCCGGAATGCCCAACGACCCAAGCCCCCTGCAAGTGGCTGTG
+
@@@FDDDFDFDBFGGGG?DBFCHHEA@@D<?FDDHGEF;AF@D@EEG@;=>?ADEB76;A3;>>?BCCCCCBBB<@B>BBABBBCC98<CCAACCBBB2>
@6SK
GAAAGCGAGAGGGAGACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGC
+
CCCFFFFFHHHHGIJJJJJJJJJJJJJIJJJIJIJJHHIIJHHHHFFFEEEEEEDDBDDDDDDDDDDDDDEEDDDDDDDDDDDDDDDDDDDBBBDDDDDDD
@6SL
GACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTAC
+
CCCFFFFFHHHFHJJIHGIJJJJJJJJJJJJIJJJJJJJJIIIJJJJJIJFIJJJHGEHHGFFFD9>CDDDDDDDD><CCDDDDDDDDDDDDDDDDDDDD
@6SM
GCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGG
+
@@CFFFFDHGFFDGGEIGIHHGAFIGADHIIJJJJJEG<F>BDHHJJICGGIJDGH@DHHGGEFHDBDB>CEDDDBBDBBBDDDDACD@BBB<A@ACCCCD
@6SN
CCGTAATAAATTGTCGAAAATACCTTCAACACCCAAATTAATACCAAAAGTTACCAAAACTGCAGACAAGCATAAAGATGTCATCATCAACCAAGAAGG
+
CCCFFFFFHHHHHIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIIJJJJJJJJJJJJJJJHHHHFFFFFFEEEEEEFDDDDDDDDDDDDDDD
@6SO
GCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACC
+
@@@DFFDDFBFFC+AFHBDCFBE?F9+<AEH@?GB>GCBBA;;1:?FDAFA?9?:(=FBGG53@EHI<E??7?;@D:B@(.(6;;5-=@;(,5(<8CAA2
@6SP
GGAAAATTCAGATGATAGCCGTAATAAATTGTCGAAAATACCTTCAACACCCAAATTAATACCAAAAGTTACCAAAACTGCAGACAAGCATAAAGATGTC
+
@C@FFFFFHHGHHIJIIJJJJFGHIIJJJJIIJJJJJJIJJIJIJJIJFIJIJJGIJIGIIJJGIJHDAHFHFFFFFEEEEEEDDDDBDDCDDDCDDDDD
@6SQ
ATTGAACTGTTGCACCGCTCCAGGTCACCTATCACGACAAATCACCGGCCTTCTCCTGACCCCGAGCAGCGGCCCCTCCGGTCCCCCCTGGACAACATGAT
+
@<@BDDDDDHHHHIIIBG<GHIGI?@??CGGEHGIIIG@FB@BFGGIFGGHEEEEF?>;CCDCA@@>BCB;;@;B>8<B<509<BBBBBBB8ACABBCCC>
@6SR
GAAAAGGAAACCTCAAGCTGAGAAAGTTGATGTGATTGCCGGCTCCTCCAAGATGAAGGGCTTCTCGTCCTCAGAGTCGGAGAGCTCCAGTGAGTCCAGCT
+
CCCFFFFFGHGGGHGHIJIJJJJIJJHHIIJJJJIJJJIJIJJIHHGHHIIJIIIJJIEBHEEHFHFFFFDEECED;ABBB?@@DCDCCD@ACD>ACCCCC
@6SS
GCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGC
+
CCCFFFFFGHHHHJIIIJJJJJJJJJJJIIJJIJJJJJIJEIIGHIIJJICHIIJIJJIJGGHJIHHHHHGFFFFFFEEEDCDDDDDDDDDDDDDDBDD
@6ST
GAAAAACCACAAGGACAGAGAGAAAAAAAAGAGGAATCTCATTCTAATGATCAAAGTCCACAAATTCGAGCATCACCTTCTCCCCAGCCCTCTTCACAACC
+
CCCFFFFFHHHHHIJJJJIJIIGHIIJJGJGHGIIIJJJJJJJJJJIGGHIHHHEFEEFDCDDEEEEDEDDDCDDDCDDDDDDDBDDDDDDDDDDEDDDDD
@6SU
CAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCAC
+
@@@ADFFFHFHHHGFHIGHIJJJJGJJIGHGIFGIIICHFGGIGGIFIIGGGIJGIIGI@GEHHHFHG;CDDFFDEAECDDDCCDDDBA@D?ABDDDBDDB
@6SV
CTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTTATGGGC
+
@@@DD3DAFBDCF@GF>F4ABHGGHIIIII??FG??@CBEG)?B<FHII:@F=FHGE@;CHHHC>=<'9=?>=@;=5==<8(5>A:A@@<+5<BCCCCABB
@6SW
CAGATCCTCACTCATCAACAGCAGCTTGAAGAACAAGACCACTTATTAGAAGATTATCAGAAAAAGAAAGAAGACTTCACAATGCAAATTAGTTTCTTGC
+
CCCFFFDDHHGHFBHGHIEHIECEGHIFGGEIIGI@FEGGIIGIIIIIFIIIGHIIGEDB>FFHIIIICEIFECHH>CFFFFCECCE>@CCCCCDDCCCC
@6SX
GTAAAAATAGGTGATTTTGGTCTAGCTACAGAGAAATCTCGATGGAGTGGGTCCCATCAGTTTGAACAGTTGTCTGGATCCATTTTGTGGATGGCACC
+
CCCFFFFFHHHFHHJIJJJJHIJJJJJJJIJJJJJJJJJJJJJJJHIDFHJHIJJJJJJJIJJJJJJJJJJIFHHHHGFFFFFFEEEEEDCCDDDDDD
@6SY
CTAGAATTAAAACATGAAGCAGAAGTTACAAATTACAAGATAAAACTTGAAATGTTAGAAAAAGAAAAGAATGCTGTGTTAGACAGAATGGCTGAATCAC
+
+1>AA>AA+2<A7AA7<AAB;@A@C=?@7?CCB?BBABB;*?=B>ABB<=>=AB?<A?ABBA;'7>A>AAB>B>A>>=A>A@>>>>>3.;>@=;,;>??A
@6SZ
ACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGT
+
CCCFFFFFHHHHHJJJHHIJIJJJJJIJJJJJIJJJJJJJJJIJJJJIJJIJIJJJJJIJIJHFHHGFFFFFFEDDDDDBDDDDDDDBDCCDDDEDDD9>@
@6T0
AGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGC
+
@@@FFDFFFGGHGJHGFEIIGDFHHFDDGIGGFFHGGIJACGGFHIIEEHIIFHFHHEF@@DDEEEEE>>ACDDDDCB?CCDD@>?@<@BDDDDDDDDDD
@6T1
GGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACAC
+
???ADD:A+AD<AEBCEB<@?B?CEIID2<AECED@?CCDADD;?@;D;@DE=.88.78@C7@:=7@A?.=ACD@ADD>@A;>?;>?AA>:AAA::3>>=
@6T2
CCACAACTGGCTATTGTTACCCAGTGGTGTGAGGGCTCCAGCTTGTATCACCATCTCCATATCATTGAGACCAAATTTGAGATGATCAAACTTATAGATAT
+
CCCFFFFFHHHGHGJJIJIJJJIIHIFIIBHIIJJIIJJJJJJIEHHJGIJJJJIEGIIJGJIEHIJIIJJHHHHFFFFFDBEEEDEEDDCDDDDDDDEEE
@6T3
CCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJHJJJJJJJJHIIJJJJJJJJJJJJJJJIHHHFFFFFEEDDDDDDDDEEDDDDDDDDDDDDDDDDDDD
@6T4
CAAGAAGGCTTCCTGGCTCATCCCAGCAGAACAGAAGGCTGTATGTTTGAAAAGGGCCCCAGGCAGTTTTATGATGACACCTGTGTTGTCCCAGAAAAATT
+
C@CFFFFFGHHHHJJJJJJIJJJIJJJJJJJJJJJJJJJJJJGJJIIJIIJIJIJJJJJJIJJFHHEFFFFFFFCCEEDCDDCCCDCBCDDDDDDDDDDDD
@6T5
CTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCT
+
@@@BDDDD?FHHHIIIBEBFDFFEB@FBBFBGGGFDG@DFGGIGIEGGIGGEGGIIIDFCEHIGIIIEFFED?DCCBBC@C>>:@@CDCCCCCCC@CCCCC
@6T6
GAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTC
+
B@BFDDDFFHGCFHIHIIIIJIIFIJJJJIJJIIIHIJJIGIHIJJJJJJJJHHHGHFFFFFCDBDD@BDDDDDDDADDDCDDDCDDDBDDDDDDDDDDDD
@6T7
GCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCT
+
CCCFFFFDFHHGHIGGIJJIJIIIGHIJDH:FIEHGGIIIIJJEIJIIJGIEHADECCEH=CBBDDEACCECAA@ACDDD?-9AACC:8??BDDBA?7?
@6T8
TTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGC
+
?@@?D;2A?<<ACGE<?FE@F<FEBFFF9FBD;8::99?):B100?FBGIC<BCEG@;CE@@E()6.7.7;@3?3.66@ACB=>;>95:3@3>??C@B@B8
@6T9
CCTGAAGAGGTGGCCCGACGTTGGGGCATTCAGAAAAACAGGCCAGCTATGAACTATGATAAACTTAGCCGTTCACTCCGCTATTACTATGAGAAAGGAAT
+
@CCFDFFFHHCFFGIIIGIICGEGGJEGGIJFJIJJIJGHIIIICGGHHHHFH@D@CCCDEEEEECECDCB@BC?CCCDBBDDDCDDDDDDCCCDDDDDDD
@6TA
AGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGAC
+
BC@FFFFFHHHHHJJJJJJJJJFHIIIIJIHIJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHHFFFFFEEEDEDDDEEDDDDDDDDDDDDDD
@6TB
GAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTG
+
C@BFFFFFHHHHGIJJJJJJJJJJJJIJJJJJJJJJGJIIIJJJJJJJCFHIJIIIEGIIJHHHHHHFFFDEEEDDDDDDDDDDDEEDDDDDDDDDDDBCD
@6TC
TTAAAACATGAAGCAGAAGTTACAAATTACAAGATAAAACTTGAAATGTTAGAAAAAGAAAAGAATGCTGTGTTAGACAGAATGGCTGAATCACAAGAAGC
+
CCCFFFFFHHHHHJJJJJJIJJJJJJJJJJJJJJJJJJJJJIJJJIJJIJJJJJJJJJJJJJIJJIJJJJIJIIJHHHHHHFFFFFEDEEEDDDDDDDDDC
@6TD
TCCCTGGCCATGCTGGACCTTCTGCACGTGGCTCGGGACATTGCCTGTGGCTGTCAGTATTTGGAGGAAAACCACTTCATCCACCGAGACATTGCTGCC
+
@@@DFBDFGBFDHF?GHIGGIGGHIGGIIIIIIGBHIGIIEDBDHHGGHGHIIEHC>7AAEFGGEFFCCEE@?ABCCCCEECCCB@BBB><AA>A@CCB
@6TE
ACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTAT
+
@@@DBDDDHF?FFGHAAEEGIGE;??BDFGHIEFHIGECEGGD@DGC<?BFEFHH>GEHAGGHEHCECEEBE@=C@ACDEC@CC>;?>59?B;;>BAAC>>
@6TF
CCAAAACTCAACACCAGGTTCACCTAACCCGCCTGCGGGATGCTGAAGAATCTATAGCATGGGCTACCCATGCTTTTCTTCCTCTGTCAAAATTAAAGTGT
+
(((29.96)84))(88(-:=.;49)))28@3(((((0((''-())))))).)))<))))))((((((,(-(((,,,((,((,,6((4+(++((+(((++(+
@6TG
CACATCCGACCGAGTCGTCCATGTACAAGTACCCTTCTGACATCTCCTACATGCCTTCCTACCATGCCCACCAGCAGAAGGTGAACTTTGTCCCTCCCCAT
+
@@@DD?DDFDFF:E?F6CGD?<D?GF@DF999<FFFIDAFD9=F9CFFEEEDA;CEDC=7?EFBD;@B>>?B?;?BBB5?9,:>(::@3@4>AB>@B?@B9
@6TH
GGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGGCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTAC
+
=1=;AA7=C7A8=7A>++2@C@=;111))::007?BBB))9=25=(=>385.=)8A66):(.A((..;@(6=;;55=5-99=6,,5+82+838??=783
@6TI
AGAGACCACTCTTTCCCCAAATTCTCGCCTCTATTGAGCTGCTGGCCCGCTCATTGCCAAAAATTCACCGCAGTGCATCAGAACCCTCCTTGAATCGGGCT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJIJJJJIIJJJJHGIHHHHHFFFFFEDDDDBDDCEDDDDDDDDDDDDDDDDDDDDDDD
@6TJ
GCTGAACAAGAAAGTAAACTTAATGAAGCACATAAGTCCCTTAGTACAGTGGAAGATTTGAAAGCTGAGATTGTTTCTGCATCTGAATCCAGAAAGGAACT
+
@@CFFFFFFHGHGICFHIIIIJJJJJIJJJJJJGFGEHIIGJGIEGGGI<GHGGIG?@FFGIJGGHII@FHII@EHCEGHHHFGFDF?CDDCCCCAE=CBC
@6TK
CCCCAATTGAAAAGAGAAATAAGGTTAATGAAAAACAGAGAAGCTGCTCGAGAATGTCGCAGAAAGAAGAAAGAATATGTGAAATGCCTGGAAAACCGAGT
+
C@@FFFFFHHHHHJJJJJJJJJJJHHIIJJJJJIJIJJJIJJJJJJJJIJJJJJJJHIIIJJJHHHHFFFFFEEEEEEEEEEEDDCDDDDDDDDDDDDDDD
@6TL
CCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCAC
+
:+=DDDDD<CBB??F<BA<GF?FEC99CD??@FEGIEFFE<B;88B;F987=7=)''5=:?7(.66>>>?A>@>;@BDDAABB<BBA>33:(:A>4+:>:<
@6TM
CTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTAT
+
CCCFFFFFHHHHGGIIHJJIIJJJJJIIIHIJJGIJIJJIIIEHIIIJJJIG=CEHHEFFFFFEEEED@BDDDDDDDCFDDDDCDBBABDDBDDDDDDDDD
@6TN
CCTGTCTCTGCTGGAAATGATGCCTATGTTGACCTTGATCGTCAGCTGAAGAAAACTACAGAGGAACTAAATGAAGCTTTGTCAGCAAAGGAAGAAATTGC
+
CCCFFFFFHHGHHJJJJJJJJJJJJIJJIIIJJJJJJJJJJIJJJJJIJJJJJJJJJJIJIIJJHIJJJJJJJJHHGHHFFDFFFFEEEEEDDDDDDCDDD
@6TO
TGCACCATAACCCTCCCACCATTGAACTGTTGCACCGCTCCAGGTCACCTATCACGACAAATCACCGGCCTTCTCCTGACCCCGAGCAGCGGCCCCTCCGG
+
@@@DD>DDA8F?:::<EE>GHI@D@FEBBC<ECDGBGE6@D<F99B?@BBB8==FGIIBE??;?CE=>?9;>:(::>@CCC@@@>-55?<5<@B<5?BB<9
@6TP
ATACACCACATGTAACATAGTGGCTTTTATTCGGGATCATACGAAAAAGAAGCTCATCAGTAGAAAGCGGAGCAGGAATGCAGGAAGGGGGGTAGAACGCC
+
0(((-.2((().))2):)))33((.2))):4)121(((0..)(((((('-.).))))):6.3)).).)-,',',4;((((((,,(((()&&&&)(++()&)
@6TQ
TATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGC
+
@?@??DDFFDHHHFEHIIBHEIIGIFCFHGIIIIIFIIGHEGHGGIGGDGFGGGGGDGGEHE=EFECB?CEECB>ACC>>@C@CCC@?CCCCCBBBCBBBB
@6TR
CTAACAGTCCAGCAGGAAGAAGGCATTTGCAGCTCCAGACTCAATTAGAACAGCTCCAAGAAGAAACATTCAGACTAGAAGCAGCCAAAGATGATTATCG
+
CCCFFFFFHHHHHJJJIJJJJJJJJJJJJIIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJIJJJHHHHHHFFFFFEEEEDDDDDDDDDFFEDDD
@6TS
CTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCT
+
@?@FFDFFHGFFHIJJJIIJJIJIFHHHJJJIJJJJJJJJIJJJGIGGIIJJIIIIIIHGIIJIJJGGHEEHFFCCBDDDDCDCDDCEDDDCCDDDDDDDD
@6TT
GAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGT
+
CCCFFFFFHHHHHJJJIFIJJJIHDHIJJJJJJJGJIJJIIJJGGIGEGIJJJGHEHFFFFEDEDDDDDDDCDDDDDDDCDDDDDDDDCCDEDDDDDDDC
@6TU
CAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAAC
+
CC@FFDDFHFDHHJEGHGHIJJIGEEFEEGIGIGGDHIIJJDIGHGGHJIIJGGJGGIJGIIJBHGGEHBEDCDDEEDEEEECBDBDDCCDDDCDCDDCDD
@6TV
CTCAGCCCCAGCAGAACAAACCAAAGAAAAAGGAGAAAGACAAGAAGGAAAAGAAAAAAGAAAAGCACAAAAGGAAAGAGGAAGTGGAAGAGAATAAAAA
+
@C@DFFEFG?FHHGAFGICHGEHIAEBGHIGIIGG@FEDGBGHHIIGBEDADFAEGIIFFFFCACBCCCCBACCBCAA>CBB8A>AA>CCBB?CCCCACC
@6TW
CCCCAATTGAAAAGAGAAATAAGGTTAATGAAAAACAGAGAAGCTGCTCGAGAATGTCGCAGAAAGAAGAAAGAATATGTGAAATGCCTGGAAAACCGAGT
+
CCCFFFFFHHHHHJJJIJJJJJJJHIJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJIJIJJJIHHGGFFFFFEEEDEEEDDEEDDDDDCDDDDDDDDDDDB
@6TX
CACACTTTGTCAGATGAGAAATGGGATGTTATTAACTGGAGGAGGGAAAGACAGAAAAATAATTCTGTGGGATCATGATCTGAATCCTGAAAGAGAAAT
+
CCCFFFFFHHHHHIJJJJIJJJJJIIIIGFHJJJJJJIIGHIHIJJIIJJJIJJIJJJJJJJJJIJJGHHHHFFFFFEEEEEECDDDDDDDDDCDDDDD
@6TY
CAACTTCTGACCCACCAGACCACCCACCCAGGGAGCCACCTCCACAGCCCATCATGCCTTCAGTATTCTCTCCAGACAACCCTCTGATGCTCTCTGCTTTC
+
CCCFFFFFHHHGHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJHHHHHHFFDEFFFFEEEEEDDDDDDDDDDDCDEDDCDCDDDDDDDD
@6TZ
GGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCC
+
@@CFBDFFHHHHHIGGGGHHIIIIGGGHGIIGIEGHG<DHGGIIIIACHEIIIFGGI@FAHHIIIGHAHFFFFFBCEDCAC=ADCDCCCCCDDDDDDDADD
@6U0
CAGGAATTTTTGTTTTGTTTTGTCTATATGTGCGGCTTTTCAGCAGCAATTTAATCAGTGTGACAGAAAAAAAAATGATTTATGGCAGCTTTTACTTTTT
+
11+22<77,@7AC+?2=+@<A;22+2+?BA=<?))):8>=*****9(.8.))//=.==>A)=).7)=7>=>@/;65(,9,((+((++((388(4:??(((
@6U1
CCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGT
+
@@CFFDFDHFHDHEHIIIGIJIIIGGIGECGIIJJJDDIIIJGIIIGGJIIJIJJIDGEGCEHAEEEFFCDEBDBCDCCDFC@CBB?9??<BBDDDD@BC
@6U2
CCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGT
+
@@<BDADBFFBFDGHGEHCHGFHHHGHHIDHGIIIIIIGDHIIIIIIIIIHGHIICHIGGGGGEHBBBC>CEEEDDDCCCCCDDD>>C@B?CCBBCBBCDC
@6U3
GTCTCCTGAGCTACATCAATGAGCTGTGTTCTCAGAAGGTCTTTGTCTCCAAGGTGGAGGCTGTCATTCACCCTCAATTTCTGGCAGATCTGCTGTCCCC
+
;1::A;;BB?AC>GGG9AFHDCA><;A@<CHG<CCGEG;?C1?F>?BF>:?9?10*7087B8BD@7=C=CGGH=C27?7?@CCEE@?A:(;5(;>5@:55
@6U4
CACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCG
+
8?@DDADDDDDHFIBHBFBFIIAHII@FEGEHGEIHIIGIHDHFGGHFHAF<FHGCHE@=EHGAAECEE?D@@DDEDCA>AACC?CC?CCCCCBBCB@BB
@6U5
CTATGATAAACTTAGCCGTTCACTCCGCTATTACTATGAGAAAGGAATTATGCAAAAGGTGGCTGGAGAGAGATATGTCTACAAGTTTGTGTGTGATCC
+
@<@DDBDDHHHBDHHGIGGGIIIC@GCGHGDG9B@GGIIB>4BDFDFGHCH<8F8BDA==@D<DE@AAH1?1(7@@>>CCDCCA>C>C><C<??BC:;A
@6U6
CTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTAC
+
CCCFFFFFHHHHHJJJJJJIJJJJJJJJJJJJJJGHJJJJJJJJJJJJJJJJHHHHHHFFFFFFDEEEEDDEDDDDEDDEDDDDDDDCCDDDDDDDDDDDD
@6U7
CCAGAAGCCCTTTTCTCCATGGCCTTTCCAGATAATCAGCGTCCACTGCTGAAGACAGACATGGAACGTCACATCAAC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJHJIJJJJJJIGIJIJJJJJJJJJJJJIJJJJJJJJJIHHGHFFFFFD
@6U8
GAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACT
+
@@BFFFFFHHHHGIJJJJJJJJJJJJJJIIJIJJJJJJJIJJJJJJJJJJJIJJJJJHIIIJHHHHEHFFFFFECEDDDDDDDDDDDDDDDDDDDDDDDD
@6U9
AGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACT
+
((79(998><?943:>.><149)@84.<;8..)1(16))).()-(.96.<6()3<:();9)..)))...)=07?=355/5;5;06;;(+8((+(2(((++3
@6UA
CTGAAGAATTCCAACCCCGACGAGATTGAAATCGACTTTGAGACCCTGAAGCCGTCCACACTGCGTGAGCTGGAGCGCTATGTCACCTCCTGTTTGCGGA
+
CCCFFFFFHHHHHJJJJJIJJJJJJIJJJJJJJJJJJIJJJJJJJJJJJJJHHHFFFDEEDDDDDDDDDDDDDDDCDDDDDDEDDDDDDDDDDDDDDDDD
@6UB
CTGGCGTGGATAAAGATGGAAGGCCTCTACAACCCCACGTCAGAGTGTGGGATTCTGTTACTCTATCCACACTGCAGATTATTGGACTTGGCACTTTTG
+
CCCFFFDDHHHHHJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJIJFHHHIJIJJJJHHHHHHHFFFFFFEDDEEDDD@CDDDEDDDDDDDDDCDDDDDD
@6UC
CAATCATCCACAGAGACCTCAAGAGTAATAATATATTTCTTTATGAAGACCTCACAGTAAAAATAGGTGATTTTGGTCTAGCTACAGAGAAATCTCGATGG
+
=+7+2<>4<CCAB37?<??=+=A++222+2+?ABB>AB7:7*:?=*70*:)70*)99A**9?)=<.3/8=AABB4:.=3AA9;A).7>>>>536>(;;;-;
@6UD
CAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCAC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJDHHGHHHHHFFFFFFDEEDDDDDDDDDDDDDDDDBDDDDDDD
@6UE
CTGGAAATGATGCCTATGTTGACCTTGATCGTCAGCTGAAGAAAACTACAGAGGAACTAAATGAAGCTTTGTC
+
B@CFFFFFHHHHFHIJIIIIDEFHEHGGGIIIHIIIJJJJJFIJFIJJIGIGHIJJIHEHGHJJJJIJIIIHI
@6UF
ATGGTCTTTTGGAATTCTGATTTGGGAGATTTTAACTCTTGGTCATCAGCCTTATCCAGCTCATTCCAACCTTGATGTGTTAAAC
+
?@@DDDDEHHF?DHIJIIIFIGEHIBBG:FFHIGGHHAFGGIDGGIIGEHJJIIGEEEGHGEEHHHGHGEAGGHHGFHFHHHFEF
@6UG
GTCATAGAGAGCTTCCAAGTTGAGAAGTGTGTAACTGAGTATCAGGAAGGCTGCCAGGGACTGGGCTCCAGGGGCAACATTTCCCTGGGTCCTGGAGAAAC
+
==;<<AAA>7;AB>9+@<<33>,A7=ACB2??<ABB@3=BAB9=?ABB>0=>5;>AABA15>AA=A=AA=9AA=435=(55=55-;;==,99=;=<83;98
@6UH
GGAAAACACGACATGTGAATATCCTACTCTTCATGGGCTATTCCACAAAGCCACAACTGGCTATTGTTACCCAGTGGTGTGAGGGCTCCAGCTTGTATCAC
+
@@@FFFDDHFHFDIIEEGIHIJJJGJIGEHIJIJIGIGHGIJJGIGGGHDHI@DFIJGCFEEGEGCEEEHFHHF@@D3===>ABB@BBDDDDDDDBCEEDD
@6UI
CTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCC
+
@CCFFFFFGGFFHJJJIHGHGJJJJJICEHIJJIIJIIGIDCGCGGEIJIIFEHGGIHGHHHHHHFFFFFECEEDDDBDDDBDACA>>>BDDDBCBCCC
@6UJ
CAGTTTCTAAAGTAAATAAAAGTTTTGGTGAAGAATCAAAAATAATGGTGGAAGATAAAGTTTCTTTTGAAAATATGACTGTTGGAGAAGAAAGTAAGCA
+
@@@DBDDFGHHGHJEGGGJJGI<FHEIICGDFHGHEDGIIJDIIGHII?FHE<FBFEGEGB@@>CGIEGCFGE>DHI>EHEHGGFFDDDCCCEC;@CDCD
@6UK
GGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCT
+
BCCFFFFFFHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJIJJJJJJJJJJJJJJJJHHHHHHHFFFFFEEECCDDDDDDDDDDDDDDD
@6UL
TCAACATGTTGTCATGACAGCCATTCAAGAGCTGATGAGTAAAGAATCTCCTGTCTCTGCTGGAAATGATGCCTATGTTGACCTTGATCGTCAGCTGA
+
CCCFFFFFHHGHHJJJJJJJJJJJJJJIIJIJIIIIJIJIHIJJJJJIAHIGIIIJIJJJJJJJJJJJJIIJJIIIIJJHHHHHHFFFFFEDDDDDDD
@6UM
CTTACTGGAGACTCAGGTGGAGTCATGCTTATATGGAGCAAAACTACTGTAGAGCCCACACCTGGGAAAGGACCTAAAGGTGTATATCAAATCAGCAAAC
+
@@@DDDB?F?FA<AEBF:FEDHHIIIIICEEEAAFHCE@GHGGIGHHGHGGEGGG@FABDCGAFHEEEHEE>HD@7?A@C(;6>C;;;>@CA@ACCCCC?
@6UN
ACAGGTTTGTCTGCTACCCCCCCTGCCTCATTACCTGGCTCACTAACTAACGTGAAAGCCTTACAGAAATCTCCAGGACCTCAGCGAGAAAGGAAGTCATC
+
CCCFFFFFHHHHHJJJJJIJJJJIJJJIJIIJJJJJIIJJJJJJJJIJIJJIEHHFHFFFFFCCEEEEDDDDDDDCDBDDDDDDDDBDDDDDDDDBCCEEC
@6UO
TTGAAAATACATACTCCTGTTAGCCAAGAAGAAAGATTGATTTTCTTAGACTCCATTAAGTCCAAATCCAAAGACTCTGTGTGGGAAAAAGAAATAGAAAT
+
CCCFFFFFGHHHHJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJIJJJJJJJJIJHEHAEFFFFDDEDDDDDDDDDDD
@6UP
GGGAAAGCGAGAGGGAGACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGG
+
@CCDFFFEFFHHHJIEHJJIGIEFFGHIJIGGIJIBGGAGGHFEHDFBBCCEEDCCBDD@=B>?B>>@DDDDACDDCDDD:@CCDDDCCDDDDBDD@BDDD
@6UQ
CTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAAC
+
CCCFFFFFHGHHHJJGIJJJJJJIJJIJJJJIJIJIIJJIIGIJJJJJJIJJJJJJIJJHHGEDBBDCDDDDDDDDDDDDDDDDDCDDDDDDDDDDD>CCC
@6UR
CAAGGCTTTAAGCAGGAGTACCACGACCCAGTGTATGAACACAACACCATGGTTGGCAGTGCGGCCAGCCAAAGCTTTCCCCCTCCTCTGATGATTAAAC
+
CCCFFFFFHHHHHJJJJJGHJJJJJJJJJJJIJIIJJJJJJJJJJJJJJJJJHIJJJJHEHHFFDDDDDDDDDDDDDDDDDDDDDDDDDDDEDEEEEDDD
@6US
TGGGATTACAGTGGTACAGAAAAAAAAGAAAGAAAAACCACAAGGACAGAGAGAAAAAAAAAAAGAGGAATCTCATTCTAATGATCAAAGTCCACAAATTC
+
<@@DDDDDFFF,AF<CCFHHIFFEFFFI7BDGGEIEE:-BCCF@FE2;@E;AEEEBDDBBBBB;-((+(2:4:A:AB::@3:44+(::@:+(4>4>?@:(4
@6UT
CATGTCTGAGACTCCTGCTCAGTGTAGCATTAAGCAGGAACGAATTTCATATACACCTCCAGAGAGCCCAGTGCCGAGTTACGCTTCCTCGACGCCACTTC
+
@@CFDFFFHGDHHIIGIGEIIIHGEFFHGIIIIHGGIIIIIHIGHIIIIIIIIIIIIFHIIIIIGIIIIIH?EEHEFDCCDDDDDBDDDDBBD<BDDDDDC
@6UU
GGTCGTACAAACTGCATCAGGAGATATGCAAACATATCAGATCCGAACTACACCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATGACATCTCCTGTG
+
??=AD@DDHHFFDGGIJJGIFHIIIGHIEIIICHIJIJGGIDHIIHGHIHIJJJJGIEEHEGIIGHIJFFEEFHFFDFEEDCE>BDCA@CCCCDDDCD>@
@6UV
GGACAAGTGCAAGCCTATGTCCTATGAGGAGAAGCGGCAGCTCAGCTTGGACATCAACAAGCTCCCCGGCGAGAAGCTGGGCCGCGTGGTGCACATCATCC
+
CCCFFFFEHHHHHJJJJJJIJJJJJJJJJJJHJJJJJJJJJIJIJJJIJJJJJIJJJJJHHHHFFFFDDDDDBDDDDDDDDDDDBD<BD<@CCDDDDDDDD
@6UW
CTCCATTTATATGAGGCAAGAAGGCTTCCTGGCTCATCCCAGCAGAACAGAAGGCTGTATGTTTGAAAAGGGCCCCAGGCAGTTTTATGATGACACCTGTG
+
CCCFFFFFGHHHHJJIGIJIIIIIIGGIIEIJIJJIGIIJHJJGHFGIJJIJJJIIJFIIJJIIIIJJJIGHGFFFDDDDDDDDEDDDDDEDDC@CDDDCC
@6UX
AAAAATTCACCGCAGTGCATCAGAACCCTCCTTGAATCGGGCTGGTTTCCAAACAGAGGATTTTAGTCTATATGCTTGTGCTTCTCCAAAAACACCCATCC
+
CCCFFFFDHGHHHJJHIJJJJJJJJJJIGIJGJJJJJJJJIIJIJDHIJJIJJJJGEHGEHHFFEDDDEEEEEFDEEDBDDDDDCDDDDDDDDDDDDDDDD
@6UY
CAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGAC
+
???DBDDD44ADDEIDA4:CFEFD+?FFI;B*?D:CFCEID9BDDEEDDIABD>CECCDECEEE@CCEECC@9A@DD==>???A>A>AAA5:AAA>>A>>
@6UZ
CCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJGIJJJJJJHIIJJJJJJJJHHHFFEFFEEDDDDDDDDEEDDDDDDDDDDDDDDDDDDD
@6V0
TGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGG
+
CCCFFFFFHHHHHIJJJHIJJIJJJJJJJJJJJJJJJIJJJIJJJJJIIJJIJJHHHHFFFDDEDEDDDDCDDDDDDDDDD@CDDEDDCDEDDEDDDDDDD
@6V1
TGGGGAGATGACAGAGGTACCCCCATGGCTCAGAGCTATGATCAGAATCCTTCCCCTAGAGCAGCTGGGGAGAGGGACGATGGCTGTCTCAGCCCAGG
+
<9939=?8)44).;):9)3=>?@83.8??1))6=8).)..3><<<<93:6;=>??5);:33=:363=99?9,936/9;<;/2&52+++:<2:<86826
@6V2
GCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJHHHHHFFFFFDDDEDDDDDDDEDEDDDDDDDDDDDDDDDD
@6V3
TGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACC
+
CCCFFFFFHHGHHJJJJJJJJJJIJJJIJJIIJHHJJJJJJJJJJJJJJJJJHHHHHHFFFFFDEEEEEDEDDDDEDDEDDDDDDD:ACDDDDDBBDDDDD
@6V4
GTACGATGTCATGCTGGGGTGCTGGCAGAGGGAACCACAGCAGCGGTTGAACATCAAGGAGATCTACAAAATCCTCCATGCTTTGGGGAAGGC
+
?8:BDDDDFD<FDGBGI@:<@?E?*C?C8??D?B?DGIIE@8B;;F@/:7?=)77?D>7@;@;65-(;>;@@>A::,<55:>>>>9502<<22
@6V5
CAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCT
+
CCCFFFFDHHHGHIJJIIJJJJGGIJIJJJJJIJJJJJJIEIJIJIJJIJJJIIJJJIJJIIHHGFFFFFDECCCEDDEEDDCDCDDDDDCCCCCBDABC
@6V6
TTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGC
+
CCCFFFFFHHHHHJJIJJJJJJJJJJJJJJDGIJJJJJJJJJJJIIIIJJJJJJJJJJIJJIJHHHHHFFFFFFDCEEEEDDDCDDDDDDDDDDBDDDDDD
@6V7
CCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAAC
+
CCCFFFDFHHHHHJJJJJJJJJJIJJJIJJJJJJJJJJJJJJIJJJJJJJJJJJHHHHFFFFEEEEEEDDDDEDDDDDDDDDDDDDDDDDDDDD<BDDDDD
@6V8
ACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGGGT
+
@@<DDD>DFDDAFHABCFGEEFGGGH?AEE@E@FGDGHGBFEAGBFHGEGDBFEHGIBGG;@CAE7=?B>>@@CA8>?@A??A??:9??::>3:3>AB(5)
@6V9
GGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTC
+
@<?DDBDDFB>DFAEHIGA<AAH@FHGEGHI@GAD>?D4?F99BG?DHIBCFH@CFE.777CCGEE;A??@DEECCC@A=?=BCCCB?BBBB?<<CB4>C
@6VA
GGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTT
+
?;?DDDFFGHHHHIJBEHIJGGIIJG<EEGHFGGHDD?GHGIIIIGEGIJJIIBCGGIJJJIJIJIGHGHGH@DEFFFBEDDDDBDBDDCCCDCC>@CDD
@6VB
GAAAAGCACAAAAGGAAAGAGGAAGTGGAAGAGAATAAAAAAAGCAAAGCCAAGGAACCTCCTCCTAAAAAGACGAAGAAAAATAATAGCAGCAACAGCA
+
CCCFFFFFHHHHHJJJJJJJJJJJJGHJJJJJIHJJJJJJJJJJJJJJJJJJJJJHHHHFFFFEEEEEEDDDDDDDDDDDDDDBDDDEDCCCBDDDDDDD
@6VC
GTGGTGTGAGGGCTCCAGCTTGTATCACCATCTCCATATCATTGAGACCAAATTTGAGATGATCAAACTTATAGATATTGCACGACAGACTGCACAGGGC
+
B?@DDDFFHHHHHJJJJJJJJJGHHIJJJIIJJJJIJJJJJJJJJJJJJIJJJJJJJIIHGIHGHIIJJJJJHHHGGHGFFFFEBDDBDDCDDCDDDDDD
@6VD
CCAGAAACAAGCCCACCAGCTTGTGGAACCCAACGTACGGCTCCTGGTTTACAGAGAAACCCACCAAAAAGAATAATCCTATAGCAAAGAAGGAGCCACAC
+
CCCFFFFFGGHFHIJGIHHIJJIGGJIIIJJIJJJ@FIIJJIJJJJJFHIGHHIGEFHHHFFFDDDDDDDBDDDDDEDDDDCCDCDDCCCDDBBD?BDCD@
@6VE
CAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGAC
+
CCCFFFFFHHHHHJJJJJJIJJJJJJJJJJJJJJIIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJIHHHHHFFFDDDDDDDDDEDDDDDDDDDDDDD
@6VF
CCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAG
+
<=7=<A77?<<;A@ABAB,>CB4?BC3A+?:?<0A7?BBB=*====9>3==A<==A)>3)=A=).==;A>=7>>;;;=<;'3''2599(,:=78?;8<<
@6VG
CTGATCTGTCCAAGCCTAAAAACCTTGCTCCTTTACAAGAGAGTCAGGAGTCTTACACAACTGGGACTCCCAAAGCAACATCTTCTCACCAGGGCCTTGG
+
:?;:DBDDFA?DCCF:?FGFIBFGFIEBEHCD<?G@F?DFADD:0?D>*?F@D???<C@1;@@F6(@E7?AEAA@?BDA@AACC;AB@BB@<?B8<8,59
@6VH
CAGAAGTCATCAGAATGCAAGATAAAAATCCATACAGCTTTCAGTCAGATGTATATGCATTTGGAATTGTTCTGTATGAATTGATGACTGGACAGTTACCT
+
??8ABDDDBFFFADE?AFHI>??H:AC>A<FHBGBF>9?1C?D?F4B@*0?0?<DFGEAFFECG?FFCEC>@@F==C@@EI@E:C?EFEA=>;?;6>3>B>
@6VI
CCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGC
+
@@@FFDDDHFFGHD@?EEECHIBAGIIIGBHGIDHGGCEGDHEGHIIIGHCCFCHGHHGHHGIIICHHFHHFB>DDECC@=ABD@BDC>@@@A@AAA:@:9
@6VJ
CTTTGTCCCTCCCCATCCATCCTCCATGCCTGTCACTTCCTCCAGCTTCTTTGGAGCCGCATCACAATACTGGACCTCCCCCACGGGGGGAATCTACCCC
+
@@@FD>DB?DFHHIDEEIEGGHDDGH@HIIGIGHEHIGGIGIGIICHGIGGGHIBFFBFAGGIGEFHE@C@CCDFCCED@BBBDBDBBBB@@B@ACDDDD
@6VK
CTCCAAGAAGAAACATTCAGACTAGAAGCAGCCAAAGATGATTATCGAATACGTTGTGAAGAGTTAGAAAAGGAGATCTCTGAACTTCGGCAACAGAATG
+
CCCFFFFFHHHHGJJJIJJJJJJJJJJJJJJJJJJJJIIJJJJIJJJJHHIJJIJIHIJJIGIFHIJJJJJHHHHFFFFFFEEEEEEEDDDDDDDDDDDD
@6VL
CTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTAT
+
@C@FDFFFHGHHHIIIEHIJIJIHIIJIIJJGGHGHGHIHJ;ADHIIIJHIHEEHHHFFFDEFEEDCDDDDDDDDDCDDDDDDDDDDBDDDDDB?CBBCDC
@6VM
CTGGATCATTTGGAACAGTCTACAAGGGAAAGTGGCATGGTGATGTGGCAGTGAAAATGTTGAATGTGACAGCACCTACACCTCAGCAGTTACAAGCCTTC
+
CCCFFFFFHHHHHJJJJJIIJIJJJJJJJJJJ@HIIIIIJ?FGIIDGIIJJBFFIJJDHCHGIJJIGGIIJIIIHHHFHFFFEEEECCECDDCCDCBDDD<
@6VN
ACTAAATGAAGCTTTGTCAGCAAAGGAAGAAATTGCTCAAAGATGCCATGAACTGGATATGCAGGTTGCAGCATTGCAGGAAGAGAAAAGTAGTTTGTTGG
+
?<?BDDDDDBFHFE<@AEH?EIEHGGGHFGEGBBD>GHDFBFGE?:DBFHGDEHH@;BHIG@FB9F>GGH@>E;E3==?EC?>BBA@CC@@C@;ACABCBB
@6VO
TCTCCGACAGCGCCAACGCCAGCTGTATCACCTGGGAGGGGACCAACGGGGAGTTCAAAATGACGGACCCCGATGAGGTGGCCAGGCGCTGGGGCGAGCGG
+
@?;DD6:@C?F8CGD:8?:CG?;FDDGDB?9D88.-.(--5=:B;???>83;88>5;@B>B@+:2)58@?B90;BB>938?@?>(28)5000809955005
@6VP
GGCCGGATGGACCCACCCAAGAACTGCCCTGGGCCTGTATACCGGATAATGACTCAGGGCTGGCAACATCAGCCTGAAGACAGGCCCAACTTTGCCATCAT
+
?;?DDA8)@:A<<?2<@@C?E;1:91*?BD?B6DDD@/99B@8;@'--....7.777).,6=@?;>5;55:5:955,:>>3><<<<8<<<3>>:4>AA9:4
@6VQ
GGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACAC
+
CCCFFFFFFHHHHJJJJJJJJJJJJJJJHIJJJJJJIJJJJJJJJJJJJJJIJJIIJJJJJJJJJJJJHHHHHFFFFFDDEEDDDDDDDDDEEDDDDDDD
@6VR
CCCACGTCAGAGTGTGGGATTCTGTTACTCTATCCACACTGCAGATTATTGGACTTGGCACTTTTGAGCGTGGAGTAGGATGCCTGGATTTTTCAAAAGC
+
@@<DDDDD@ACFF>CEHGAECDHHIIGB<EEFGHGI;GHDH@DGHGHEFHGHIGIIGGBH@FHGIGEEGH=?D;=6;;>6>@A@A@A2@CCCCCCCCCC8
@6VS
GTTCAAAATGACGGACCCCGATGAGGTGGCCAGGCGCTGGGGCGAGCGGAAAAGCAAGCCCAACATGAATTACGACAAGCTGAGCCGGGCCCTCCGTTATT
+
CBCFFFFFHHHHHJJJJJJJJJJJJJGIIJJJJJJJJJJJJIIDDDDDDDDDDDCDDDDDDDDDDDDDDEEDDDDDDDDDDDDDDDDDDCDD@DDDBCDDD
@6VT
CGCCGCCTCTCCCCGGCTGAGAGAGCTCAGGGACCCAGGCCGCACCAGGAGAACAACCACCAGGAGTCCTACCCTCTGTCAGTGTCTCCCATGGAGAATA
+
CCCFFFFFHGHHHJJJIJIGIJJJJIJJJJJJJJJIJJJJJJHHFFEDDDDDDCDDDDBDDDDDDDCDDDDDDDDDDCDDDD>CDDCDDDDDDDDDDDDD
@6VU
GCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGC
+
CCCFFFFFHHHHGJJJGIIJJJJJJJJJJJJJJJJJJJJIJJJJJGIGIJIJJJJJIJJIJIIJJHHHHHHFFFEFFEECCCCDDDDDDB@DDDDDDDD
@6VV
CCCTTCCCACCACAAGGCTTTAAGCAGGAGTACCACGACCCAGTGTATGAACACAACACCATGGTTGGCAGTGCGGCCAGCCAAAGCTTTCCCCCTCCTCT
+
@@<BDBBDHDHDBGB@AF?EGGEAGGHB;E:D@DGD?@D@@=BB<=BB=<FHAGGG@DAEHFHD;CBCCC;,5>?BB8<128<??CCCCC:>>CBBBBCCC
@6VW
GAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGC
+
@@@FFFFFHHHHHIIJJJIIIJJJJJGIJJJJIIJJJJJJIJJJJJIIIJJJJJIGHFFFDDDDDDDDDCDEDDDDDDDDDDDBDDDDDDDDDDDDDDDDD
@6VX
ACCGGGCCTTCCCAGCTCACCTCCCTCCATCGCAGTCCATACCAGATAGCAGCTACCCCATGGACCACAGATTTCGCCGCCAGCTTTCTGAACCCTGTAAC
+
@@@DFDDDDFHHHHFHDAGIFIGGGGHHIGFIGII??BF@?FAHG8BF@DHEG>CEH>EHACEEFECDACC>CCCDBDDDDB@DCDDDDDBCCDDBDD:4:
@6VY
CTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCC
+
CC@FFFFFHGHGFGJJGIJIJIIJIFGGGIIJJJIGIIIJJIIFGHGJJJIEGIIDHIJHHHHGEFFBFFECEEDDDDDBBBDCCDDDDDDBDDCDCDD
@6VZ
CTGAAGCAGAGGAAACCTCGGATTCTTTTTTCACCATTCTTCCACCCTGGAAACTCTATACACACACAGCCGGAGGTCATACTGCA
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHFFFFDDDDDDBDDDEDDEDD
@6W0
GGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJFHIJJJJJJJJJJJJJJJJJGHHHHHHFFFDEEEEDDDDDDDDDDDDDDDDDDDDDDDDDDDD
@6W1
TCTCAATTGCAGGAAAAGAAACTCTTTCATCTGCTGCTAAAAGTGGTACAGAAAAAAAGAAAGAAAAACCACAAGGACAGAGAGAAAAAAAAGAGGAATCT
+
CCCFFFFFHHGHGHIIIJIJJJGIIJJJJIHGGIIGIJJJIEH:DGFGIJJIJJIJJJIIIIIHHHHHFFFDDDEDDDDDDDDDDDDDDDDDDDDDDDDDD
@6W2
GGAGATATGCAAACATATCAGATCCGAACTACACCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATGACATCTCCTGTGACTCTCACCTCTCAGACAAC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJIJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJIIIFHIJJJJHHHHHHFFFFFFEEEEEEDDDDDDDDDDDD
@6W3
CCGGCTGAAGCCCACTATGACCCTGGAGGAGGGACTGCCATTGGCTGTGCAGGAGAGGGAGCACACCAGCAACTTTGACCGGATGATCTTTTATGAGATGG
+
@@8DD?8:CDBDDFIAFIIEHIIIE3):C1?DF>BFBDFF@<9.88C.88@DD(-(---,''(;.>B;;?5?B5@BB@B>;905>::4>4:>A34(++:44
@6W4
ACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJGIJJIJJJJJJJJJJIJJJJJJJJJJJJJJIJJJIJHHHHHFFFFFFEDDDDDDDDDDDDDDDACDDDEDDD9>9
@6W5
CCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTAT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIHHHFFFFFEEEEEDDDEDDDDDDDDDDDDDDDDDDEDDDDDDDDDDDDDD
@6W6
GGATCACTTCAGCTCTGGCAGTTTTTGGTAGCTCTTCTGGATGACCCTTCAAATTCTCATTTTATTGCCTGGACTGGTCGAGGCATGGAATTTAAACTGAT
+
CCCFFFFFHHHHHJJJJJJJJFHJJJJJGHIJJJJJJJJJIJJJJJJJJHJJJJJJJJJJJJJJJJJJJJJJHIGHHHHFFDDDDDDDDDDDDDEDDDDDD
@6W7
GGAAGATAAAGTTTCTTTTGAAAATATGACTGTTGGAGAAGAAAGTAAGCAAGAACAGTTGATTTTGGATCACTTACCATCTGTAACAAAGGAATCATCAC
+
@CCFFFFFHHHFHIJJIJIJJJJIJJJJJJIGFHHFHJJHIIIJJDGGIIJIIJJIIHJIGEIJJJIIJJIIJJJIHHHFHHD;ADDDFCDECDDDDCDDD
@6W8
ATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGC
+
?@@DADDE?DFBCGBHGEHGHIIIIIGGI<GHGIIIGGIIHGCGIIIHIIIIIIIDHIIIGHHAECADEFFDBACECCCCCDCDEC@C@CACB?ACDDDD?
@6W9
CGGGTGTGAGCCATCGTGCCCGGCCTGCAAACACATTTTAATTGACAACACTAGGGCTGTTGTACAAAATAGTAATGATAGCCATGGAAGTTTTACCTTAT
+
+:;AAA?1A+<2++2?+@;;A)00:A;AAA*)9==AB?<9><<7=A9===<B>>AB>(5.).7?>>@@=..6((--;(5;((5(5(::;:5;3;;488:=;
@6WA
AAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTAC
+
@?;DD:DDHHDHH@DBB?F?F<BEGEFGIHGIIIIHDG@FHBGIIEBCFDEEHFFHHEEEBCCCCA>C@CCCACC<A<::>@@CC@:+4>>>>AB?8@>::
@6WB
GGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTC
+
C@CFFFFFGFHHHJIJJIJIIIJJJJJJJJIGIJJIIJIJJJIJJJGIJJJCGEHIJIJGIJHHHHHFHFFFEDCCEECCDDDDDDDDDDDDDDDDDDCDC
@6WC
CCTCATTCAGGTGATGTGCTCTATGAACTCCTTCAGCATATTCTGAAGCAGAGGAAACCTCGGATTCTTTTTTCACCATTCTTCCACCCTGGAAACTCTAT
+
CCCFFFFFHHH?FHEHGIJJJJJJJIJJJJIIJJJJJIJJIJJJJIJJJJJIJJHIJJJJJIJHIIIIIIJJHHHFFFFFFEEDEEEDDDDDDDDDDDDDC
@6WD
GCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATAC
+
@CCDFFDFHHHFFHDHHDEHFGHJJJJJJIJIEGGIHIGIGGIIJGGIJIIFGGIEIIHHHHHFFFFDEE>CCACCDDBDDDDBDCDCB@CDDCDCCDDDC
@6WE
CATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATAT
+
@@@DBDFFDFDHHII@FHIIIIIEBH<?CBGFGH9BDDHIHGIIICHIIGGFBD>@FHIEFHGIIIGHEFDFFACCCABBCC@@CECCCCCCCC>CCCCC@
@6WF
CTGAAGAGGTGGCCCGACGTTGGGGCATTCAGAAAAACAGGCCAGCTATGAACTATGATAAACTTAGCCGTTCACTCCGCTATTACTATGAGAAAGGAATT
+
CCCFFFFFHHGHHJJJJJJIIJJJJJJJJJJJJJIJJJIIJJJJJJJHHHHHHHFFFFFFEEEEEEEDDDDDDDDDDDDDDDDDEDDEEDDDDDDDDDDDD
@6WG
GGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATAC
+
C@@FFFFFGHHHHFJIHIJIJJJJIJIJJIIJJIJIIJJJJJJJJJJJJIIJJJJIGJJIJGGFFECEEEEEEEDDDDDDDDD?BB?CDD?ABDDCCDDDD
@6WH
CACTGCGTGAGCTGGAGCGCTATGTCACCTCCTGTTTGCGGAAGAAAAGGAAACCTCAAGCTGAGAAAGTTGATGTGATTGCCGGCTCCTCCAAGATGA
+
=71?AA8<0AA><@7+<+2)<?=7@<=A<=>A>A=?47*<4'<A(8>>BABA;>27>>7>@@@3=;;;=55;3;5;=9>5;35795-9098339?=388
@6WI
GTTTTTGCAGCCTCTACAACCCCACGTCAGAGTGTGGGATTCTGTTACTCTATCCACACTGCAGATTATTGGACTTGGCACTTTTGAGCGTGGAGTAGGAT
+
@BCFFFFFGHHHHJJJJIJJJJJJJJIIIIHJBDGGIGEHHIIIGIJJJIAHIIJIJJJJJJJHHHHHHFFFFFFEECEEECDDDDDDDDDBDBDCCDDDC
@6WJ
CCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGC
+
BCCDDFFFHHHGHJIIJJJJJJJEHIJIGIJJHIIJJIJJIJIJJJJIJJIIJJIJIIJIIJJIHHHHHHFFFFFDDDDDDDDDDDCCDDDDDDDDDDDDB
@6WK
GTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGC
+
CCCFFFFFHHHHHIJJJJJJIJJJJFHIJJJIJJIJJJIJJJJJJJJJJJJJHHHHGFCEFFFEEEEDEDEDDDDDDDACDDDDDDDDDDDDDDDDDDD
@6WL
CTCAAGCTGAGAAAGTTGATGTGATTGCCGGCTCCTCCAAGATGAAGGGCTTCTCGTCCTCAGAGTCGGAGAGCTCCAGTGAGTCCAGCTCCTCTGACAGC
+
?=?::BD:+AA?:C:2<?<3<AC?CFF>B)):)00*:DB99B<D898?DC(8=)=((--17=)=?=7?@@@/;>;;AAA,,(5,:AAA>:>>9>AA>AA><
@6WM
CTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGGCTAGTCAACCTCAATCT
+
@@@BDD?D?BDADBEB>+<:F>HIFGE3:C8):FCG@GGIAFCBFHIC?9=BC<C3CFEEB=?BCCB>6>5??;;?@B5(,5:(+2>?:@DC>8(3:@:@:
@6WN
GGACACGTGAATATGGCATTCTCTCAGTCCAACCCTCCTTCGGAGTTGCACAAGGTCCACGGATCCAGAAACAAGCCCACCAGCTTGTGGAACCCAACGT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJIIIIJJJJJJGIIJJJJHHFFFFFFEDEDDDDDDDDDDDDDDADDDDDDDDDDDA
@6WO
CCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGACTGCATCAGGAGATATGCAAACATATC
+
@@@DDA?<DACFBEE>BF9DGGFGD;EFGGGHD><:BFCHIIEF@@FDBFHDEAH@G@FA@@>ABHEDBC;6>@CC;@355A>A8?:@CC@DAC?@>C>:
@6WP
CTTCAGAAGAGAAATCATAAAGACAGCCAGTTCGAAACTGATATAGTACAACGAATGGAACAAGAAACACAAAGAAAGTTAGAACAACTCCGGGCAGAGCT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJIJJJIJJJIIIJJJJJJJJJJJJJJJIJJJIHHHHFFFFFEEEEEEEDDDDDDDDDDBDDDDDD
@6WQ
CTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACC
+
CCCFFFFFHHHHGJJJJJJIJJJJJJJJJJJJJJJJJJJJJJGJJJIJJGJIJJJIIHHBEFFDDEEEDDCDDDDDDDDEEDDDDDDDDDDDDDDDEDDDD
@6WR
GCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACA
+
CCCFFFFDHFHHHIIJJIIGHIJIJIJIJJEGHJIJJGHIIJIIJJJIEIIJJIHHFHFFFFEDEDCDCDDDDEDCDDCCCDACDDCDCDDDDDD0<BCD
@6WS
CACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCC
+
@@@B?BDDHFHBA@GEE?DIHGIGHICGCE8?DGECFCBCHCHEGI4?<DGG@B>AHCEDFC>CCH;=?7A??EEEE@?>A@ACB@C>BBB@29<@<9?B
@6WT
CAGCAGCCAGTGTACATTCCGAAGAAGGCAGCCTCCAAGACACGGGCCCCCCGCCGGCGTCAGCGTAAAGCCCAGAGACCTCCTGCTCCTGAGGCACCCA
+
B@@FFFFFHHHHFGGJIJJJJIIIIJJJJJJJJIJIJJJJJJJJJJIJJJJFDDDDDDDDDDDCD@BDDDDDDDBBDCCDCDDCDCADD?CCCBDDDDDB
@6WU
CGAGATGCAGTCCTGGAAAATCAAAATAAAACTCTAATAGAAGAGTTAAAAACTTTGAAGGATCTTTATTCCAATAAAAGAGTTTGATTCCTAAGAAAGA
+
??<B+22ADD2<A:A+CEEFD><FFIIICBDEEDECBDFCFIIIIADEIDDEDICD:@DABBC3BCEEIIEEICA;CCD;(.7??AADDDB.>A3@A?AA
@6WV
GCAGTTTTATGATGACACCTGTGTTGTCCCAGAAAAATTCGATGGAGACATCAAACAAGAGCCAGGAATGTATCGGGAAGGACCCACATACCAACGGCG
+
@CCFDFFFHHHHHJIJGHJJJHIIIIHIJJJJIIJJJIJJJJJIJIIIJHJIJJJJJJJIJIJJJJIGIGEHHHHFFDDDDBDDDDDDDDDDDCDDDDD
@6WW
TGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCT
+
@@@BDFFFHCFFHIGIIGJJJJGIJGGIIJJIIJJIIIJJJJCHJFEGHIJJJJJJJJJJJJIGGGJJHHHHHGFFFFFDEEDE>ACCDDDDDDDDDDDDD
@6WX
GGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJIJJJJHHHHHFFFFFFEEDDDDDDDDDDDCEDDDDDDD
@6WY
CAGAAAAAAAAGAAAGAAAAACCACAAGGACAGAGAGAAAAAAAAGAGGAATCTCATTCTAATGATCAAAGTCCACAAATTCGAGCATCACCTTCTCCCC
+
CCCFFFFFHHHHHJJIJJJJJJJJJJJJJJIJJJJIJJJJJJHFDDDDDDDDDDDDEEEEEEEDDDDEDDDCDDDDDDDDDDDEDBDDCDDDDDDDDDDD
@6WZ
TGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACAC
+
@@@BDDDFHDFHHGGIGIHEDHEIIIIJICBGGCHGJIIGIIJIJJGGHGHHIIIIAHEIIGHIHEGJHFEHFCFFFDABDCCDBCCDDDCCDCAAACC@C
@6X0
CCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGG
+
@@@DDDDDBHHHHIIIGBGHGGHEHGGGII@GIEGJIJEGEIIGIIIBFEHGGIJGJJJIJFGIIIHFEEEDFF<ADDB?B?ABDDCDDEEEEEC@BBBD
@6X1
ATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGT
+
@@@BDDADDHFH>BBDEGEC@GDHIGIGIIGDHGIEBHIDDDHIIIBFAABD==?AEHHFD@B?BDABC@CD@;>C@A>@CBCD>CCCCCCDC@CDBB@@0
@6X2
GTCGTACAAACTGCATCAGGAGATATGCAAACATATCAGATCCGAACTACACCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATGACATCTCCTGTGAC
+
@CCFFFFFGFGGHIJIIJJGHIHIJJJJJJJJIJJIIJJJJJJIIIIJJIIJJJJGIIJJJJJJIJJJFJHHHHFFFFFCCE>ACCCEDCDDDDDDCCDCD
@6X3
CTGGACCTGGAGCGGCAATTCACTAACAAGAAAACAGGGAATTTTTGGGAAATATGAAAAGCCAAAATTTGTGCAGTGTTTAGCATTCTTGGGGAATGG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJIJJJJIJJJJJJJJJIJHHHHHHHFFFFFEEEDEDDDACADDCDDEDDDDDEDDEEDDDDBDDDD
@6X4
CAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATAT
+
BB@FFFFFBFHFHIIIIGIIJJJJJFGIJJIGGHJJJJIJJIIJJIJJJJJJJIJJJIJJIJJJHHHGFFFFFFDEEEDCCDDDDDDDDDDDADEDEDD
@6X5
GGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCC
+
@CCFFFFFHHHHHJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHHFFFFFFEEEEEEDDDDDDDDDDDDDDDDDDBDDDDDDDDDDDD
@6X6
GGTAGCTCTTCTGGATGACCCTTCAAATTCTCATTTTATTGCCTGGACTGGTCGAGGCATGGAATTTAAACTGATTGAGCCTGAAGAGGTGGCCCGACGTT
+
CC@FFFFFHHHHHJGIJJIJJJIJIJJJJGFHEGIJJFIJJHGGHJJGGIIHIJGEBGHGIGIGHIJGHHFG:;@DEDE;ACECDDDDDABDA9<BB>@>B
@6X7
AAGAAATAGAAATACTTATAGAGGAAAATGAGGACCTCAAACAACAATGTATTCAGCTAAATGAAGAGATTGAAAAGCAAAGGAACACTTTTTCATTTGCT
+
@?@DDDDDDABHFHBED<<CHAE>;FH@<<9CG3:EBGGBA?FFIHGII9?FHG<DHIGGICHH@FG;F@ACDGIIHBEH@;9>DF@CEA>CACCCA@A@(
@6X8
AAAGAATTGGATCTGGATCATTTGGAACAGTCTACAAGGGAAAGTGGCATGGTGATGTGGCAGTGAAAATGTTGAATGTGACAGCACCTACACTTCAGC
+
CCCFFFFFHHHHHJJJJIIJJJJJJJIJJJJJJJIJIIJJIJIJ?FGHJIJJFGFHIGIJIJJ@DEHGJFIHIDEFEH=ADDFFBCBDEECCCDDDDDD
@6X9
ATACGAAAAGGTTATTAGGAAGAAGCTATGACGCAGTATCCGGGGAGCTGCACGGAAAAGATTGTGGGGCCCAGACGGTGGTTGTAAAGGGCCTGTGCTG
+
00((2((-0)-)))))))).)(().))).:))5(-00.)0)(0(---'.))))(',,'(((-(((5,''')&(+((&&&20&++&(((((((+++(((((
@6XA
GAATATATTAAAATGTTTATGCGCGGTCGGCCAATTACCATGTTCATTCCTTCCGATGTTGACAACTATGATGACATCAGAACGGAACTGCCTCCTGAGA
+
@@CFFFFFHHGHHJJIJJJJJJJJJIJJJJJJJIJJJJIIJJJJJJIIJJJJJJJIHFHFFFFFFDEEEEEEDEDDDDDDDDDDDDDDDDDDDDDDDDDD
@6XB
GGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATC
+
??7BDADDA>FAFAHGEG;EGGHGGEGIGH@BGGG@DGIBFHGAFIDFC=CCGGIGIICCHEHAEDE18;ACCBBB?CCCACA?B:>>@>:C@CCC@B94>
@6XC
CAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCAC
+
CCCFFFFFHHHHHJIJJJJJJJJJJJJJJJIIJIJIJJJIJJJJJJJJJJJJJJJJJJJGHHHHHHHHDEFFFFDECCDDDDDDDDDDDDDDDDDDDDDDD
@6XD
GGAAGACCTGGCTTACATGAACCACATCATGGTCTCTGTCTCCCCGCCTGAAGAGCACGCCATGCCCATTGGGAGAATAGCAGATGTGCAGCACATTA
+
CCCFFFFFHHGHHJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJIIJJIJHGHHFFFEFEEEDDDDDDDDDDDDDDDDDEDDDDDDDD
@6XE
GAGAAATCATAAAGACAGCCAGTTCGAAACTGATATAGTACAACGAATGGAACAAGAAACACAAAGAAAGTTAGAACAACTCCGGGCAGAGCTGGATG
+
CCCFFFFFHHHHHJJJJJJJJJIJJJJJJJJJJJJJJIIIJJJJJJJJJJIJJJJJJJJJJJJJJJJHHHFHFFFFFFEDEEEDDDDDDDDDDDDDDD
@6XF
CAGATACTTGTGCCCAGCAATCAGGTGGTCGTACAAACTGCATCAGGAGATATGCAAACATATCAGATCCGAACTACACCTTCAGCTACTTCTCTGCCAC
+
@CCFFFFFHHHHHJJJJJJJJIIIJ:CECFHIJJIJJGJHJJIJIGIGIJIJIJJJJJJJIJJIGGIJGHHHHFFFDEEEEDDDDDCDDDDDCDDDDDDD
@6XG
CCCAGGCCATCCGTGGATAATGTGCACCATAACCCTCCCACCATTGAGCTGTTGCACCGCTCCAGGTCACCTATCACGACAAATCACCGGCCTTCTCCTG
+
CCCFFFFFHHHHHJJJJJJJJJIGJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJIJJHHHFFFFFEEEEEDDDDDDDDDDDDDDDDDDDDDDDDDD
@6XH
GGGAGACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTT
+
CCCFFDFFGAFHFHGGBHGCIIJJJIGHGEFGIIJDHIJJJGIEHEBEFFFDDDDDDDDDDEDDDCCDCCDDDDDDDDDDDDBDBBDDDBDDDDDDCCCDD
@6XI
CCCCCTCCCACGTATGAGTCGGAGGAAGAGGACAAGTGCAAACCTATGTCCTATGAGGAGAAGCGGCAGCTCAGCTTGGACATCAACAAGCTCCCCGGCG
+
CCCFFFFFGFHHDHHJIFEHIIHJJJIIEHGIJFIIBGHDIJJGIGGGGIJICHIIJHEHHFFFFDDDBBDDCCCDDDDCCCDDDDDCBCD:ACDDDDDD
@6XJ
GGCTGAATCACAAGAAGCTGAATTAGAGAGGCTGAGAACACAGCTTCTATTTAGTCACGAAGAAGAGCTTTCCAAACTGAAGGACGATTTAGAAATTGAAC
+
+?;;ADBA?A2+2<A2CC?EFC>?BE422<)1)1:?*:::?D;89B9?9/9DBB*08BADADIA;AD977.7AA;.?;A(6(..(,',55,,,(,554>A:
@6XK
GAGATGAGAGACCACTCTTTCCCCAAATTCTCGCCTCTATTGAGCTGCTGGCCCGCTCATTGCCAAAAATTCACCGCAGTGCATCAGAACCCTCCTTGAAT
+
?;?ABDB?BD;FF>BD@EFDEDBGIGIEHFHIGHIIIIIGIDHB<BF@F<368CFGIIBEEEHEDEDB?CC;65;?@B?<>>C>@@CCCCBBBBB?AC@>A
@6XL
CTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATG
+
@@@DFFFFDHHHGIJIJGHIFEGIIJJJJJIIJEFHEEHHHHIJJJIFJIJJIJGGIJGHGHHE>DFFEDDDEB>CDCDCDB;@CDCA?CDDDC?CDDDDD
@6XM
CCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTAT
+
@BCFFFDFHHGHHJJIJJIJJJJJJJJFIJJIIJDHIIJJJIIJGIJJIIJFEHFBDFFEEDCCDCDECDCCDDDDDDDBBDDDDDEDDBDDDBBDDDDDD
@6XN
TGCATCAGAACCATGAAGAAGATAACTGTGTCCAGAGGACCCCCAGGCCATCCGTGGATAATGTGCACCATAACCCTCCCACCATTGAACTGTTGCACCGC
+
7?;DDDBDBHBFFHGHDAEB?G<CEFDHBFEDGH>GIHAC;?DHBHI<FHIIIG5@FH;DC==EHAEADB@D@>;?;?=B;=BBCCCA:@C@(::>ACCBB
@6XO
CTTCTGCTACAGCTCTGATTGTGCCATACTGATCAGGAACCTCTATTTCTCTTTCAGGATTCAGATCATGATCCCACAGAATTATTTTTCTGTCTT
+
CCCFFFFFHHHHHJJJJJJJJGIJJJIJJIJIIGJIJIIJJJJJJJIJJIJJJJJJJJJGJJIIEIJJJJJJJJGJJHHHGHHHHFFFFFFCCCCE
@6XP
CTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTAT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJGHJJJJJJJJHEHHHHFFFFFFEEEEDDDDDDDDDDDFDDDDDDDDDDDDDDDDDDDDDD
@6XQ
CGAGCAGCTTGCAGCCCTCTCTCAGCCCCAGCAGAACAAACCAAAGAAAAAGGAGAAAGACAAGAAGGAAAAGAAAAAAGAAAAGCACAAAAGGAAAGAGG
+
@@<:D<DD:CBA>:EFBFF;<?AFFG@F<B;FFFDD;FDE?8BB??FF=88;@9=@AC;77???@;B>>A@3;55;?=88??BBB<??<?B@>@8>A?>??
@6XR
GATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGC
+
@CCFFADFFDFDHIIIBGIHI?GEHIGGGDDHEIGIIIEHHEEDBDGFGHHIIGAHEE>BDFCCC>,;CCCBACCC;;@C?>B?CABB@BCBBACCDCCA
@6XS
CAGGTGTTCATTTATGTGTTATTGATGACTCCAATGAGCATATGCTTACTGTATGGGACTGGCAGAGGAAAGCAAAAGGAGCAGAAATAAAGACAACAAAT
+
B@CFBDDDFHHHHJJJHGHGJJIIJIIGGJJJJJJIIJJIGIGIIJGHIHIDGIIIIGIIJJGHGGIJGGIIIJJFHHHFFFFECECCCDCCDDCCDDDDD
@6XT
TCTAAATGAAGAAGTTAAATCTTTAAAGCAAGAGAAAGAACAAGTTTCATTGAGATGTAGAGAGCTAGAAATCATTATTAACCACAACAGGGCAGAAAATG
+
<??1DADDAFFF8E,<EGBA<A?DHDFC<+3A@ED@G@E?91CD?FE<FFAEBD@GFF@FGFAF@F@CFIGIECEEEFE=AACEFDDDBCBC?=>?AB9>A
@6XU
CCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJHHHHHFFFFFDCEEEDDDDDDDDDDDDDDDDDDD
@6XV
GCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTAT
+
CCCFFFFDHHHHHIIJGIJHIIIJJJJJIIJJJJJJJJJGIJJJJJIIIIIJJJJJIIIJJJIJJJIJHHHHHGFFFFFEEEEEDDDDDDDDDDDDDDDDD
@6XW
GCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCGCC
+
CCCFFFFFGHHHHJJGJJJJIIIJJJJJIGGJIIJJIJJDGDGEGIIJJJJFHGGJGGIFGIIIJIIIJHHHHF@EFFDEDDDDDDBDDCABDBDCCC@BD
@6XX
CAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGC
+
CCCFFFFFHFHHHJJJGIIEGDHHHGGJIJDGHIJJIIGJGJJIJFIHIJJIJJJJGHGHJJJJJHHHFFFFDDEDEDDDDEDDDDDCCDDDBDDDDEDD
@6XY
CGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGC
+
@@CFFFFFFDFHHJIIGGIGHGIIFHIJJGGGEG@FGDHHIIIJJJIEHHAE7@DCEHEEHEDFD8?=BBDBBDDCDCC?C@AACDCC<9A??BDDDDDD
@6XZ
ATTTTAGAAGAAAAGTGTGCTCTACAGAGACAGCTTGAAGACCTTGTTGAAGAATTGAGCTTTTCAAGGGAACAGATTCAGAGAGCTAGACAGACAATAGC
+
@CCFFFFFHDHHHJI?EHHIIJJGJJJCGCHIJIGIIIIJJJJJJJJJJJJJIIHJGGIJJJJJJJIJJIIIGHFFHHHFFFFFDDECCDCDDDDDDDDDD
@6Y0
TTCGCCGCCAGCTTTCTGAACCCTGTAACTCCTTTCCTCCTTTGCCGACGATGCCAAGGGAAGGACGTCCTATGTACCAACGCCAGATGTCTGAGCCAAAC
+
?<@DAD<DDAAAFIBEFEGDG3?8?DGGF??9?BGGA99D3<?BFCFIEFE;;=>:@?=?9;;15=?;?<1@:>4>@@@@B8@B@B8:@+:(:>>BB?<??
@6Y1
CGGAGAACCTGAGACACCTTAAGAACACCATGGAGACCATAGACTGGAAGGTCTTTGAGAGCTGGATGCACCATTGGCTCCTGTTTGAAATGAGCAGGCAC
+
CCCFFFFFHHHHHJJJJJJJJJIJJJJJJJJJJJJJJJJJJJIJJJJIJJIFHIJJIJJJJJJJJHHHGGFFFFFFEDEEDDDDDDDDDDDDCDDDDDDDD
@6Y2
GGGAGACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTT
+
@B@DFFFFHHHHHJIIIIJJJJJHIIFHIDHHIGIHJJJJJIJIIHEHFFFDDDDDDDDDDEDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDCED
@6Y3
AGAGAACTCAGCGACACTACCTGGGCCATACAGACTGTGTGAAATGCCTTGCTATACATCCTGACAAAATTAGGATTGCAACTGGACAGATAGCTGGCGTG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJFHHHIJJIIJJJJJJJIJJJJJJJJJJJHHHHHFFFFFFEEEEEDDDDCDDDDDDDDDDDDDBB
@6Y4
GGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGC
+
@@@FFFFFHFHHHGGBHIEHIGEHIJGGHGGDHHFGJFHGIGGHGBCCBFHGJGIIEEHB?@BDDDDCDCDDDDDCCADDDDCBBDDDD@DD@B:CADDDB
@6Y5
GGCAGAGGAAAGCAAAAGGAGCAGAAATAAAGACAACAAATGAAGTTGTTTTGGCTGTGGAGTTTCACCCAACAGATGCAAATACCATAATTACATGCGGT
+
CCCFFFFFHHHHHJJJJJJJJJJIIJJJJJJJJJJJJJJJJJJJJHIIHJJJJJJJIGIIHIEHHHHHHHFFFDEEEEEDDDDDDDDDDDDEEDDEDDDD@
@6Y6
TGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTT
+
@@@DDDDDBF;B<<:4CGE:AEF?<@9BE@;E@FFF8?????<*?FFE<F>?D9CDF;@8@>FEFIIFDFCE;@>B?DAACCB;;828=<@AAA>ABABBA
@6Y7
CTTTGGCTGATGTTTTGAGGCGTCTTGCAATCTCTGAAGATCATGTGGCCTCAGTGAAAAAATCAGTCTCAAGTAAAGGCCAACCAAGCCCTCGAGCAGTT
+
@@@FFFFDDDFHHGGHHFHHGIGGIEGHIIGDBHIHEGGIHIIGCBCGIDGHIIFFDGIGEB?CDDFDCCEA@;@AC@:=ABBBBBDB<?B?A>&0<BCDC
@6Y8
GCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGAT
+
CCCFFFFFHHGHHFHHFHJEIGGHIIJGIGHGGHIIIIHIEHHCEHGHIJGHC@EGGHHEHHDFFFFBEECECDDBBD@BDDDDDBDDBDDDDDCC?CCD
@6Y9
TACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCT
+
CCCFFFFFHGHHGIJJJJJJJJJJJGG?HGGHIJJIIIHIJJIJJJFHIIJJHGHGGDEEDFCEECDEEDDCDDDDDDCDDDDCCDCCABDDDDDDDDDDD
@6YA
GCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGC
+
@@@DA?DDBFHDFGII@FBG?E9@CBHEIGGEIDGIIIBIIIGHEIIGIIHIIIIGCHEHGD=@CHBEAEDEEDBCCCCCCCCBCBCACCCCBCCCCCB@
@6YB
CAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCC
+
CCCFFFFFHGHHHJJJJJJJJJJJJJHIJJJIJIJGHHGIJJJHIJJJJJJJJJJJJJJIIGHHHFFFFEEEEEEEDDDDDDDDDDDDDDDDDDDDDDDD
@6YC
GCCCTTTTCTCCATGGCCTTTCCAGATAATCAGCGTCCACTGCTGAAGACAGACATGGAACGTCACATCAACGAGGAGGACACAGTGCCTCTTTCTCACTT
+
@@@FFFFDHDHFH9CEGHGHGIIIIGFDHFDFHEHEDDFHHGGJJIJIEHIHJHHGEACDHIHIFIEHEEEEFFDCCB6?ADDCD:@CCDDDDDDDCDD@C
@6YD
GCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACC
+
=?@DFFFFHGFHHGJGGGJEFHCFHGJIIIGEGIIIJEGGEHIGIGGHEEHFFDFFFFEECEEEECDDDB?B?ADBDCD>A@BBCDDDBDCCCDDDCDDDD
@6YE
ATAGTATTTCTGCTGCAAGTACTTCTGATGTTCAAGATCGCCTGTCAGCTCTTGAGTCACGAGTTCAGCAACAAGAAGATGAAATCACTGTGCTAAAGGCG
+
@@@DFFFFGDDDHIGIIJIIIJJJJIJJIIIIJJJIIIIIGIJJGIJJJJJIJHEHDHHIJJGGGIGGIJJCIIFHHHHFFFFFFCCECCCCDDDDDCDD@
@6YF
TACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTT
+
CCCFFFFFHHHHHJJJIJJJJJJJIIJJJJJJIJJJJJJJJJJIIJJJJJJJJJJJJJJJJJIJJJHHHHHFFFFEEEEEEEDDDDDDDDDDDDDDDDCD
@6YG
TTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGC
+
@CCFFFFFHHHHHJJJJJJIJIIGEHIGEGHGHGG@HHC9FHIHIBHIIJJIIJJIJIGJIJJHHHEHEFFFFFE@CEECDDDCCDDDDCDDCBBDDDDB?
@6YH
CCCAGGCTCTGCAGCCACATCCGACCGAGTCGTCCATGTACAAGTACCCTTCTGACATCTCCTACATGCCTTCCTACCATGCCCACCAGCAGAAG
+
CCCFFFFFHHHGHJJJJJJJJJJJJJJJJHHJJJJJJJHIIIJJIJJJJJJJJHHHHHGEFFFFFEEEEEEDDDDDDDDDDDDCDDDDDDDDDDD
@6YI
AAAAATTCGATGGAGACATCAAACAAGAGCCAGGAATGTATCGGGAAGGACCCACATACCAACGGCGAGGATCACTTCAGCTCTGGCAGTTTTTGGTAGCT
+
@@?DDFDFGFGDFIGIJJDGIEGGIGHCGEHIJJJJIJ<FCFHJGE@FHE2=5CCHHG@CAEFFFDD@DD>A?A>>CCDDCCCCCDACB9@CA@DD?@CC@
@6YJ
TTCGACTGATGACTCTGAGGAGGAGCGAGCCCAGCGGCTGGCTGAGCTCCAGGAGCAGCTCAAAGCCGTGCACGAGCAGCTTGCAGCCCTCTCTCAGCCCC
+
@@CFFDFFHHHGHIJIJJJJIJJIIJJJJIJGJJEIFIJIJJJHFHHFEFEFEDCCDDDDCCDCDCBD=@BDCBBBBBDBCDCBCCDBBDDCCCDDDDDDD
@6YK
ATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCC
+
@@@FFDFFGHHHGJJJJIJGGGHEGGICHHIJIJJJIJICCBEHIJIIFGIJIIJIIJJJJJIGJJGHGHGHHFFFFFCDEEDDDDDDDDDCDDDDDCDDD
@6YL
GCCTCATTACCTGGCTCACTAACTAACGTGAAAGCCTTACAGAAATCTCCAGGACCTCAGCGAGAAAGGAAGTCATCTTCATCCTCAGAAGACAGGAATCG
+
@?@DDD>DFFBDDGEG@G<:A:<AB@AFFBGIIIFII@BDDDGFDD99*BG???FCFIA@D@E@A=>?AB36.).6;@;;A>@AB;>;;:?:55??@B@42
@6YM
CAGACATGGAACGTCACATCAACGAGGAGGACACAGTGCCTCTTTCTCACTTTGATGAGAGCATGGCCTACATGCCGGAAGGGGGCTGCTGCAACCCCCAC
+
?;;DDDA3CDCD>EBEC4,3<A;<A1C<@DD>))))?*9?D38BB8=)/8.)=C)==@@AA=AAC;;);;;;;)6>9>??;5/8;>3&((+((4><>5>95
@6YN
GAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAG
+
@@@DDDDDHGGFHGIIIGGDGIIJJJJIIGHJJIIJCHGAHGGBHGGGIGEIG;CEFDBCEE@CCEDDDDDD@BDBDDDDDDDDDDDDDACCDCCDDDC
@6YO
AAACAGGAACCCAGAGATTTTGCATATGACTCAGAAGTGCCTAGCTGCCACTCCATTTATATGAGGCAAGAAGGCTTCCTGGCTCATCCCAGCAGAAC
+
:>+?<=3;<++)<3++@+?@<@A@<+?AA**1**1*11**0*:)7?=7=*=37>/=AA)=)>)>A>AAAAB)=AA3>3.77>>;((;;=2;5;9(9;3
@6YP
GGGACCAGATAATTTTTATGGTGGGACGAGGATACCTGTCTCCAGATCTCAGTAAGGTACGGAGTAACTGTCCAAAAGCCATGAAGAGATTAATGGCAG
+
<@@FFDDDDHHDHHIIIBIIGHHBG;?CD@EHEHIGDFHFDDGHCACECHIIIAHHGECEHHAE;.;;>>AA@CCDDA?5;ACCC@A?9@AC@3>C<CD
@6YQ
TGGGAAAGGACCTAAAGGTGTATATCAAATCAGCAAACAAATCAAAGCTCATGATGGCAGTGTGTTCACACTTTGTCAGATGAGAAATGGGATGTTATTA
+
:;?D+==A?DDD;E?CEE3A3<AAC>CFC?<?C9CEEB@?8??9:?D;<*09/0??BD87)88@(@=;==;@CC>.==?3?@@7?>;:;;(,(5>A>5,>
@6YR
TGTACAAGTACCCTTCTGACATCTCCTACATGCCTTCCTACCATGCCCACCAGCAGAAGGTGAACTTTGTCCCTCCCCATCCATCCTCCATGCCTGTCACT
+
@??DDDDDCFFFHJJJGGGHJJJIJIIJJGIIGJIJJJIGIIJJIIJJJJGIFGGGIIIGGGGIIHGHHGGIIJHHGDFCEFCEEEEDCCCCDDCACACCD
@6YS
TTACAAGCCTTCAAAAATGAAGTAGGAGTACTCAGGAAAACACGACATGTGAATATCCTACTCTTCATGGGCTATTCCACAAAGCCACAACTGGCTATTGT
+
CCCFFFFFHHHGHJJJJJJJJJHJJJJJHIJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHHHFFFFFFEDECEDDDDDDDDDDDDDDDE
@6YT
CAGGTGGTCGTACAAACTGCATCAGGAGATATGCAAACATATCAGATCCGAACTACACCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATGACATCTCC
+
11=A42A=<@@<DDEGIIGDECFCHHIGIGCBFHHIIGGGGDDHIGGGEEHGBHHGIGA;=CGGCAHCCEEBBDDBA;>@A@@CC(;?5?@@CDCCCCCC>
@6YU
CATCATGCACCCTCTGATCCTGAACCCCCGGCACTCCGTGGATTTCAAACAGTCCAGGCTCTCCGAGGACGGGCTGCATAGGGAAGGGAAGCCCATCAACC
+
@<?DDDD?FFABBBAGBFEHEHBEFEEFEHIGHG@FAF8B@GEFGD=@EDA@EEEEE@D66;>>=>>;89=9;559<>@>>@?CBBB<2<2?B<8A9:>??
@6YV
AACAGATTGTGCAAAAGAACCAAGAAATAAAAAAAACATGAAATTAGAGCTGACTAATTCTAAGCAAAAAGAAAGACAGTCTTCTGAAGAAATAAAACAGT
+
@<=;DBD::CFF>FFE9@CFEFFA;@BH9E<EGEGEFBFDFDFFCCFFIF>777=D7?C)?=?E;@D>7;=@@BABBBBB::55@(5555?3>@@:>:<9A
@6YW
CTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACT
+
CCCFFFFFHHHGHJJJJJJJJJHIJJJJJJJJJJJJJGIJJJJJJJJJJJIJJIJJJHHHFFFFFEEEEDD9?CCDDDDCDDACDDDDCDDCDDCDDDDDD
@6YX
CCGACGTTGGGGCATTCAGAAAAACAGGCCAGCTATGAACTATGATAAACTTAGCCGTTCACTCCGCTATTACTATGAGAAAGGAATTATGCAAAAGGTGG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJIJHHHHFFFFDDDDDEDDEEDCDDDDDDDDDDDEDDEDDDDD>AB
@6YY
GGAGTACCAGGGCGTCATTGCCTGGCAGGGGGACTACGGGGAATTCGTCATCAAAGACCCTGATGAGGTGGCCCGGCTGTGGGGCGTTCGCAAGTGCAAGC
+
BCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJHFFFFDEDDEDDDDDDDDDDDDDDEDDCDDDDDDDDDDACDDDDDDDDBDDDDACDDDDD
@6YZ
CCTGTAACTCCTTTCCTCCTTTGCCGACGATGCCAAGGGAAGGACGTCCTATGTACCAACGCCAGATGTCTGAGCCAAACATCCCCTTCCCACCACAAGGC
+
CCCFFFFFHGHHHJJIJJJIJJJJJJJIJIIIJJJJJJIJIJJIJJHJJIJJIEHHEEHFFFDDBDA>;ACDDDDDDDDDDCDDDDDDDDDDDDDDDBBDD
@6Z0
GTGGGGGCTACGCAAGAACAAGACCAACATGAATTACGACAAGCTCAGCCGGGCCTTGCGGTACTACTATGACAAGAAC
+
@@@FFFDDHFAFDIIIIJJJIIIGGIJIJJJIJIJJIIJJJJIHHHHHFFFDDBDBDCCDD;@DDECDDEDDDDDDDDD
@6Z1
GTTTCACCCAACAGATGCAAATACCATAATTACATGCGGTAAATCTCATATTTTCTTCTGGACCTGGAGCGGCAATTCACTAACAAGAAAACAGGGAATTT
+
CCCFFFFFHHHHHJIJJIJJJJJJJJIJJJJJJJJJJJJGIJJJJJJJJJJJJJJJJJJJJJJJJJJIJIHFFDDDDDDDDDDDDDDDDDDDDDDDDDDDD
@6Z2
CACCGCTTTGCCGATAGAATATGGTCCACTTGTGGAAGAGGAAGAGAAAGTGCCTGTGAGGCCCAAGGACCCTGAGGGGGTTCCTCCTCTCCTGGTCTCTC
+
=??1B>:DFFBAD)@GE<FHCEFFCGEGID@GB>?3?>?;D?FBFFIFBF7=9@FE4@;@DEFFDDBB>@B=@@9;?BBB05?BBBBBBBBABBB:ABBBB
@6Z3
TGTTGAAAAGAGCCTGGAACTTCCTCCAGTACTCGTGCGAGGCGGCGGAGGGCCGGGCGGCCAGGTGGTGCGAGAGGGGCGTGGGGCAGGCCAAGGAGGTG
+
(8(-=6=))2(<7()((.;6))).8:))22).))1(((-:(<(-53'3,&0&&+)&0)050&)(+(45&((0&5&&85&)8&05&8&&0:-(+(26(+&+(
@6Z4
CTTTATTTCCCTTTTCATAGACAACAAATGAAGTTGTTTTGGCTGTGGAGTTTCACCCAACAGATGCAAATACCATAATTACATGCGGTAAATTTCATATT
+
@?@;D?A:2A?F>::C<<D@IE?EFFIAHAE<B1:1CBG3D:?DF:??9;09??/?82BFC=C3=E;DFEE:77?)7?BDB7@?.(33,,;5>(,;>A;BB
@6Z5
ACAGAATCAAAACTGAAGTAGGAGATAATTGGAGGCTAAAGATAAGCAATTTAAAGAAAATTTTAAAAGGAATCTTGGATTATAATCATGAGATTTTAGG
+
@CCFFFFFHHHHHJJGIJHHJGHJIGIIIJJJFIJJJJJGIJJJIIJJIJJJJJJJIJJIJJJIGIJJJIJIJIHFFHFEDFEEFFDCEDEDECDDDDDD
@6Z6
CCACGAAAAACCGCGTCGCCGACCGACCAGTCTCTAACGTAAAAAAACGATTTAGAGTAAAATCAAAACAAATGATAGCCAAACAAATTACTTATGAAAGT
+
;;(--(<;((((0(2((((-(0-';='-9(;)(6(9((((,(9((3:&0&(+((((((++(+3:<<==7(68:<((+(((++((2(+(((+4(((+(((+(
@6Z7
AACAGATCCTCACTCATCAACAGCAGCTTGAAGAACAAGACCACTTATTAGAAGATTATCAGAAAAAGAAAGAAGACTTCACAATGCAAATTAGTTTCTTG
+
?@<DFADDHFDAFIGEHDDFGIGIDGDFHBGHCEHII@@?B?DF?@HGIIIIGGADGA8C<CDGHG@BDEHECE>A;?CB77>@CC6;;@>CDD5>@DDAC
@6Z8
CTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTAC
+
C@CFFFFFGHHHHJJJJJJJJJJJJJJJJIJJIIHHIJJJJJJIHJJIIJJIHGHGFFDFEDDFDEE@CCDEDDCDEDDEDDDDCDB:ACCCDDDDDDDDC
@6Z9
AAATGAGTCAAAAGATAGAAACCATGCAGTTTGAAAAGGACAATTTGATAACTAAGCAGAATCAATTAATTTTGGAAATTTCAAAGCTAAAAGATTTAC
+
CCCFFFFDHHGHHJJJJJJJJJJIJJJJJHIJIIJJIJIJJJJJJIIJJJJJJIJJJHHJIJIIJGHJIJJJJIIIHHEHHHFFFFFFEEEECBDDDDE
@6ZA
AGATGGAGCTGCAGAGCCCTGAGTACAAGCTGAGCAAGCTCCGCACCTCGACCATCATGACCGACTACAACCCCAACTACTGCTTTGCTGGCAAAACCTCC
+
@@@AD?DDFDHAHGEIIF?GHI;ACCAFBGGG>CBHD@;9BFD@GDG@CF8@AHDHEHCACEB'9>;ACC><?8??83>@::>@ACC4(:>7AC(9?BACB
@6ZB
GTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGC
+
CC@FFFFFHHHHHJJJJJJJJJJJJCGHJJJJJJIIJJJJJJJJJJIJJJJIHHHHHFFFFFFEEEEDEDEDDDDDDDACDDDDDDBDDBDDDDDDDDD
@6ZC
GGAGAAAAGTGCCTGTACAATGTCAGTGCCTATGATCAGAAGCCACAAGTGGGAATGAGGCCCTCCAACCCCCCCACACCATCCAGCACGCCAGTGTCCCC
+
BCBFFFFFHHHHHJJHIJJJJJJJJIHIJJJIIJIJJJJJJJJJIJJJJDGHIIIJJJJIJJJJJJJJJIHHHDDDDDDDDDCDDDDDD<BDBBCCDEDCD
@6ZD
CTTGGTGATTTAAGGCGGCAGGTTAAACTCTTAGAAGAGAAGAATACCATGTATATGCAGAATACTGTCAGTCTAGAGGAAGAGTTAAGAAAGGCCAACGC
+
@@@DDADB>FD?B>F?EDHGIGGGHGI<???FFGGHDEBDHDGIGBGE@EH7CDH:>EFEEECD>B7>ACC;;@@>A@ABB<?A>CCDCCCCCB@?AB?80
@6ZE
CCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGT
+
BBBFFFFFHDFHDIJJJIIGCFHHIIJJJEIIJIEHIJEGEGIGIGJJJIIIHCEHHEFFFFFFEEEEEDCBB>CCDACDBDDDDDCDDDDDDDDCCDDDC
@6ZF
GTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGAT
+
@?@DDDFFHHHGHIFGEGDB@GEHDGGG@?FHIJGIIHB?DHFGGEHIIBGHGEIGDHHEIGIGFEEHFDFC>@DCDEEEACD?@?BBDBDD>ACDD@CDC
@6ZG
TCCACAGAGACCTCAAGAGTAATAATATATTTCTTCATGAAGACCTCACAGTAAAAATAGGTGATTTTGGTCTAGCTACAGTGAAATCTCGATGGAGTGGG
+
@<@DDDDDFDHFFIIGHAG<FHGIIGIGGIIIIIIIGGGGHIGHIIIIGHHGIIIIEFFDFHIIIIIIIIIEDHIDHIIHHHFFHEDEDDDCCDCCBABB?
@6ZH
GGATGGCACCAGAAGTCATCAGAATGCAAGATAAAAATCCATACAGCTTTCAGTCAGATGTATATGCATTTGGAATTGTTCTGTATGAATTGATGACTGG
+
@@@7DBEDFDFFDDHGGGHGIIEGGHGEGDFGIIIIIFAGHGIGIIDGIIHEGHICG>AF)=CCCAGGECCGCDHGBGGHGDEFAACCD@DFFDECCA@B
@6ZI
GGCTGTTGGTGTCAGCCAGGAGGGTCCTCCAGGCCTTCCGCCTCAGCCTCCACCACCAGTTGCTCAACTGGTCCCCATTGTGCCCCTGGAAAAAGCTTGGC
+
@@@?A?;B?:<ACEH>FH>GIIBBC9?DCCC<3BBGAFE>@16@E@GEGCAAEEE@CA;73;;3?DC@CCC>3>??C=@>CC@CCB<@ABCC?ABB349??
@6ZJ
CAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCG
+
@C@FFFFFHHHHHJHIIJJJJJJJJJJJJJJJJJJJJJJIIJJJJJJIJJJJIEGIJJIJJJJJJJHHHHFFFFFEEEEEDDDDDDDDDDDDDEDDEEEED
@6ZK
GTTGAAAAAAACTTTGAAGTTAACTATCAAGAGTTACAAGAGGAGTATGCTTGCCTTCTCAAAGTAAAAGATGATTTAGAAGACAGTAAAAATAAACAGG
+
@@@DDDDDF?DAFHIEGDHA<GEFCGIGIGGDEDFH>GDGBHDDGIDGGIIIF@GHIICEIIIBGGIHHHEEDDEEEE@CCC@CAC>CCCCCBCCCC@CB
@6ZL
CCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCG
+
C@@DFFFFHFHHGIGGHIIEGFHHIIIIIFGBHHIIJGGGIJJGHIGHIJJJIJJJJIEGIGAGHEI@AEHEBBDEEA?EDDDDDCCD:ACCCCDCCCDDB
@6ZM
CAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATAT
+
CCCFFFFFFHHHHJJJJGIIJJJJJHJJJJJJJJJJJJJJJJJJJIJJJJJJIIJJJJJJJJJJHHHHFFFFFFEEEEEDDDDDDDCDDDDDCCEDEED
@6ZN
CCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTAT
+
CCCFFFDDHHHHHJIJIEHGGIJJJEEHGIGIHIDBFIEHIJGGAFEGHGIGHEFDFFEEEEEEDDCEDCCCDDDDDDDDDD?CC@DC<8CB8<ABCDCDC
@6ZO
CTGATGGGCAGATTACAGTGGGACAAAGAATTGGATCTGGATCATTTGGAACAGTCTACAAGGGAAAGTGGCATGGTGATGTGGCAGTGAAAATGTTGAAT
+
?@@ADDFFHHHHHJGIJIHGIIGGHGGHGIJJIDH@FHIEFHFDHIJJJGHJJJIGIICIIIJFIJJIEGFEHHFFBCDFEBACCCD=CDDCDAC@@@CCC
@6ZP
GTGCAAGCCTATGTCCTATGAGGAGCAGCGGCAGCTCAGCTTGGACATCAACAAGCTCCCCGGCGAGAAGCTGGGCCGCGTGGTGCACATCATCCAGTCAC
+
+1:<AAAACB><72<@<=,337A3++2<CAAAAAAABA9A4=AA3>=AB;AB=6=5>=>A@66===:;;<8:79;<9059&&09;;(8:7;+(:=?3533:
@6ZQ
CCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGG
+
@CCDDDFDFGBHHIIGD<FEHGGHIIHGIIIIIIHEBFEGHHIIGEGHEDBFHIIEICBHIIBA?ADFDBCDDECCEA>B?BB<ABBBCB>@@>ACAACCB
@6ZR
GAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGAC
+
@@?;DDDD?F;CD:?BF?A1CFCCFHGGEHAHDFHBCBFGB9FHGCHGEAAB>>25?D@D@>6;>@CCC@>;;68;<8<?<@??CC9:32>@>A34+49>?
@6ZS
CAGCGAGAAAGGAAGTCATCTTCATCCTCAGAAGACAGGAATCGAATGAAAACACTTGGTAGACGGGACTCGAGTGATGATTGGGAGATTCCTGATGGGC
+
C@CFFFFFHGFFHIJIHIJJIJJIIIJEIJGGIJEHHGGEGGIJIIIJJJJJJJIJJJJFFCCHHGFHFFFDBC>?ACCEDEDDDDDDDDDDDDDDDDDD
@6ZT
CTCCTCCTTGCCTGAAGCCAGTCAAGAGGCAGGGAGCAGAGGCAATTCCTTTTCTCCTCTGTTGGAAACCATAGAACCTGTCAACATACTAGATGTTAA
+
@;?DFDADFFFCFEHIDCDHGHDEEE>CFGC?@F1??DHGG;=FEFHIIGGGG@FFHGIGC)7?AAAADF?;BAC>;=C95>ACC:<@@>>CCCA5>>>
@6ZU
GGAAGAGGACAAGTGCAAGCCTATGTCCTATGAGGAGAAGCGGCAGCTCAGCTTGGACATCAACAAGCTCCCCGGCGAGAAGCTGGGCCGCGTGGTGCAC
+
@@<DDDDFFHHFFHHCHGGHIGHEHIJJGIGIHHIJJJEEHIIIHIIGEHEHIJJIC;AEEHFFFF?A>ACDD@BB>BBDBDDDDDDDBDDD5>B<?CDC
@6ZV
CGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCT
+
CCCFFFFFHHHHHJJJJJJJJJIJJJJJJJJHIHJJJJJJIJJJJJJJJJJJJJJHJIIJJJJJJJHHHHHHFFFFDDDDDDDDDDDDDDDDDDDDDDDDD
@6ZW
CCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGT
+
CCCFFFFFHHHGHJJJJJJJJJJJJJJJJJJJJJJJHIJJJJJJJJJJJIJIIIJJJJJJJJJJHHHFFDDDDDDCDDEEEEFDDDDDDDDDDDDDDDDC
@6ZX
GGGAAAGCGAGAGGGAGACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGG
+
CCCFFFFFHDHHHJJIJJJJJHIJIJJJJIIJJJJGHIBHIHHHHFFFDCEEECDDDDDDDDD@DDDDDDDDEEDDDDDDEDDDCBDDDDDDCDDDDDDDD
@6ZY
CCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTAT
+
?:+A++::=B?:<AE<A?3<3+)<@?EE4DD>4**?D?*:3*900B??D4?B<D:B.8.=AACC=.7ACCCAD<688;?=>>A:3:>A5=<29<(4((44+
@6ZZ
GATTAAACAGGAACCCAGAGATTTTGCATATGACTCAGAAGTGCCTAGCTGCCACTCCATTTATATGAGGCAAGAAGGCTTCCTGGCTCATCCCAGCAGA
+
B@BFFFFFHHHHHIJJJIJJGJHIJGGIIGIJIIIIJGCHCFFHHIJJICGIHGHIIJCHGHIIGGGIGIJJJHHFHEFFFFEEEECDCCDDDDDDDDDC
@700
CCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTCCTCCCCTTGGAGGGGCACAAACGATCAGT
+
?@<D+A?AFHDFDGBGH>>FFGBHHDAGEH@:CEGDDH<9CFFHCGIGHIGGIGGHCCFHGGBBHEE;@DECCCCCBBC=C<>C?=<BBBCBBBB5@B@>A
@701
AAACAGGCCAGCTATGAACTATGATAAACTTAGCCGTTCACTCCGCTATTACTATGAGAAAGGAATTATGCAAAAGGTGGCTGGAGAGAGATATGTCTAC
+
CCCFFFFFHHHHHJJJIIIJJJJJJIJJJJJJJJJJJJJJJIJJJIJJIJJJJIIIJJJJJJJJJJJGHHHHHHFFF;@BEEDDBDCDDDDDDEDEDDED
@702
AGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGC
+
@@@FFFFFHGHGHJJJJJJHIJHIIJJGIJIIJJIJJJJJJIIIJIJJJIGHGGIIJJJJJJJJIGCGHHFFDEEEDEDCEDDCCCDCDDDDCDDDDCCD
@703
TGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGC
+
BCCDFFFFHHHHHIJJJJIJJIJIJJDIIIGIIJJJJJJIIJIJJJJJJJJJJIIJJHIJJIHHHHHFFFFDEEEEDDCDEDEEDEDDDDDDDDDCDDDB
@704
TTTAAATTCAGCTATGGAGAAAAGTGCCTGTACAATGTCAGTGCCTATGATCAGAAGCCACAAGTGGGAATGAGGCCCTCCAACCCCCCCACACCATCC
+
=<>AA4?77ABABBB7=++337A+A=7?<A<+21:::?=7A:=<=?4?:???A>3?AB;97;(.)/7=AB>>>AA7AAAA=>>@/33==;;-8982(8;
@705
CGGCTACCCCATGGAGCACAGATTTCTCCGCCAGCTTTCTGAACCCTGTAACTCCTTTCCTCCTTTTCCGACGATGCCAAGGGAAGGACGTCCTATGTACC
+
;(7((2>??919;<?()@3<1):;4;))8-(3;/3).).7:<?):=1.<9>???;??;>3313;):)).(,9=/(95;:;/((,;9(2(&006:5::://:
@706
GCAGGGCTTCTCTGTGGAACTGGAAAGTGAAATTTCAACCACAGCAGATGACTGCAGTTCAGAGGTAAATGGTTGCAGTTTTGTGATGAGAACAGGAAAGC
+
@@@DDDDEDHFFHJFHJJIGHEEGGHICFHHG>FHGIIJCHJJGIIIGHHHHHGJEGCCFDCGHG=CEHGIJCHHFHF@?@DE6@>C@A@CDDACDDDDD?
@707
GACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTG
+
?@@DDDAA?D?FFHGB?FFFE8;CFHE>FHGGDEGCHIGB?DHB<=B=FBD=CGC;@DHE)===@BDE>B;@CCCCC3;=?;@B<<??>>@>>:??B?@?1
@708
AGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACT
+
CCCFFFFFHHHHHJJJJJJJGGIJJJJJJJJJJJJJJIIJFHIJJIJJJGHIJJJJJIJJJHHHGHHFFFDDDDEDDDDDDDDDDDEEDDDDDDDDDDDDD
@709
AGAAGACCCTTCTTCTGACTCAGCCAGAAGAGGAGAATGGGGCAATAACATGAATTCTGGCCTCAACAAAAGTCCTCCCCTTAGAGGGGCACAAACGACC
+
;;<;(484;4))8))).6;.);.).<7=9<;<(1(((:?>((0-7=><>1<>)<9>1).)).)..86).(.<.;8).9=5=7(-6(35',3((8/85:&)
@70A
GTTCATTCCTTCCGATGTTGACAACTATGATGACATCAGAACGGAACTGCCTCCTGAGAAGCTCAAACTGGAGTGGGCATATGGTTATCGAGGAAAGGACT
+
@@@FFFFDHHHGHGGGHGHGEGGIIJJJIJJJIJIJJJIJJIJJJJJJJJJJGGGEHIJGGIJJJJIJHHHGF7?BFBAC>CEDCCDDDDBDDDDDDDDDD
@70B
CCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTAT
+
CCCFFFDFHHHHHJJJIJJIJJHGIIJJJJJIJIHIIIJJJJJFJJJJJJJJJJJJJJGFHGHHDFFFFEEDDCDDDDDDDDD?BCDDDCD?DB:<CCCDD
@70C
CAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCC
+
@;;AD?DB?FHH?FDFHIG?<<CGHIIHDD?:BD39090B88B?CF<B=<CA>8@DC4@=E3AA;=;7?@B>>@>=;((559?<C?25,;+:@C>CBB5@
@70D
CGAGTTGCAGTCCTGGAAAATCAAAATAAAACTCTAATAGAAGAGTTAAAAACTTTGAAGGATCTTTATTCCAATAAAAGTGTTTGATTCCTAAGAAAGA
+
BCCFDFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHH?EHHFFFFFFFEEEDEEDDD
@70E
GAAGAAGAGCTTTCCAAACTGAAGGAAGATTTAGAAATTGAACATCGAATAAATATTGAAAAACTTAAAGATAATTTAGGCATTCACTATAAACAGC
+
CCCFFFFFHHHHHJIJIIIJJIIHGFHJJIIJGGJJFJJJGJJJJJJJJJIIGGIIJIJJIJJEGGGIIIIGHHGJHFHGGHFFFFEFEDDDEDECD
@70F
CCAACCCCGACGAGATTGAAATCGACTTTGAGACCCTGAAGCCGTCCACACTGCGTGAGCTGGAGCGCTATGTCACCTCCTGTTTGCGGAAGAAAAGGAA
+
?@@FFADDHFDHHJIGGIGGHGHFCA?GHJEGGCHIJJJIHGHIIIHHFDBEF@ABCBBDCCCB@??DD;;C:@ACCCBBC>>CCD@BB@DBBDDDDBDD
@70G
GCCACCACCGCCTACTTCCTGTACCAGCAGCAGGGCCGGCTGGACAAACTGACAGTCACCTCCCAGAACCTGCAGCTGGAGAACCTGCGCATGAAGCTTCC
+
@@CDFFF@DHAHFIIIIGIIIHEHGGIIIIGIIIIIIIIGHIDIDHHGHHGEFFFFDCCEEEDDDCBDDDC?BDDDCDCADDDCBDBB>B9@BCDCDDDDD
@70H
TCTAAAGTAAATAAAAGTTTTGGTGAAGAATCAAAAATAATGGTGGAAGATAAAGTTTCTTTTGAAAATATGACTGTTGGAGAAGAAAGTAAGCAAGAAC
+
CCCFFFFFHGGHHIJIIFHHJGGCFFGHIIJGIGIIIJJGIJJFGGHIJIGIJJJIIJJJJJJIHJJGIGIIJIGHJHHHGFFFFFEEEACEE>CDDDC?
@70I
CGGATGGACCCACCCAAGAACTGCCCTGGGCCTGTATACCGGATAATGACTCAGTGCTGGCAACATCAGCCTGAAGACAGGCCCAACTTTGCCATCATTTT
+
@CCDDFFFHHHGHIIJIIIIGHIGGGGGIJJGGHFHEIIIIGFIIJIGGD@GEH@EHEHGGGFBDDF@CCECDC@;A>?CBB5?@DBCCCCDDCCDCCDCD
@70J
CTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGC
+
CCCFFFFFGGHHHHIGGHJIJGGGGJJIGIGIJIIJIJJJJJJIJJJIJGHEHHIIJJIJIIJJJJJIHHGGHFFFFFEEEDECDDDDDDDDDDDDDDDDD
@70K
GTGAGTTGGCTGGGAAGCAGCATGAGATTGAAGAGCTAAACAGAGAGCTGGAAGAAATGAGGGTTACCTATGGGACTGAAGGACTGCAGCAGTTACAAGA
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJIJJJJJJIIJIIGJJJGHJHHH@EHFFFFEDEEEEDDDDDDDDDDDDDDDDDD
@70L
CAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTG
+
C@@FFFFFHHHHHJJJIJFHIIJJJIJJJJJIJJJIIIGIII;FCHIIJJGDGHHHHFFDFEDECEEDDDCC@CC@CCDDDCACFDDEDDDDDBB@ACDCD
@70M
CCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACAC
+
C@@FFDEFHGHGHJJIGFIIJJJIJGHHFGHHIGIHJJJJGGIIJJGHGIJIEIIJGJJGIGHIIHHHDFDFFFFDCCCEEDDDDDDACCC@CCDDCDCDD
@70N
AGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACC
+
@@@FBDF??CF?DFDEHIIIBGGIGDDDCHEHGIIIIIFG@DA?FEIIBEHGEABBDDBDC>AACEC@CCCBBB?>8?B8ABBCCCA:AACCCCCCCCCBB
@70O
CAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCT
+
C@@FFFFFHHHHHEEHIIIIICHEFEFHIIIIIIIHAGGGIGCHIIIIIEGIII;FHIIIIHFHGHD?B?CECD>CDDD@ADCCDDDB?BCD>@CBBDBC
@70P
GCCCTCTCTCAGCCCCAGCAGAACAAACCAAAGAAAAAGGAGAAAGACAAGAAGGAAAAGAAAAAAGAAAAGCACAAAAGGAAAGAGGAAGTGGAAGAGA
+
CCCFFFFFHHHGHJJJJJJJJJJJJJJJJJJJJJJJJIJIIJIJIJJJJIIJJIIIJJIHHHHHFDDDDDDDDDDDDDDDDBDCDCDDBDD:ACCCDBDC
@70Q
GACAAGTGCAAGCCTATGTCCTATGAGGAGAAGCGGCAGCTCAGCTTGGACATCAACAAGCTCCCCGGCGAGAAGCTGGGCCGCGTGGGGCACATCATCC
+
=7=AA;2<<A><2<22<233<33,33@==22)1?:4:00;*=7A==A=->7A;=7.).(=2>3>;4=</,;0&&++83+2115;5;50&)&&2+83+:(:
@70R
AGACAGACATGGAACGTCACATCAACGAGGAGGACACAGTGCCTCTTTCTCACTTTGATGAGAGCATGGCCTACATGCCGGAAGGGGGCTGCTGCAACCCC
+
CCCFFFFFHHHHHJIJJJJJJJJJJJJJJJJJJJJJJJJIIJJJJJJJJJJJJJJJJJJJJJJHHHHHFFFFFEEDEEDDDDDDDDDDDDDDDDDDDDDDD
@70S
CCCCACTGCATCATGCATCTCCAAACTCAACTCATACACCGAAACCTGACCGGGCCTTCCCAGCTCACCTCCCTCCATCGCAGTCCATACCAGATAGCAGC
+
CCCFFFFFHHHHHJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHFFFFFEEEEEDDDDDDDDDDDDDDDDDDDEDDDDDDCCDDDDD
@70T
CACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGAT
+
CCCFFFFFFHHHHJJIGHIIJJIIJJJJJJJJJJFIGGGIJIIJJDHHIIJJJEIJJJJJJJHHHHFFFDCDEEDDDDDDDDEEDDDDDDDDDDDDDDDCC
@70U
CACCCCTGCTTGTCATAGTCACAACTCCATCTAATAAAGAGCTTACTTGAGTATCACATGACTGTACATTTTCTGCCCTGTTGTGGTTAATAATGATTTCT
+
CCCFFFFFHHHHHJJJJJJJJJJJJIJJJJJJJJJJJJJIIJJJJJJJJIJIJJJJJJJJJJJJGJJJJJJJIJJJJJHHHHHCEFFDEEEEEEDDDFEDE
@70V
CCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTAT
+
C@CDFFFDHHFHDGBHIJFGGIGEGFFGIIGIHEFHIIJGDDEHJJIIJJJHFFDDFFCCECDCCDDEDCDDDB?BDDB?@BB@CCDDBDDDDBDB?CCDD
@70W
AGGGGGGTCAGCTGAGCCCTCTCAAACTCAGAACTTTATCCTTACTCAGACTGCCCTCAATTCGACTGCCCCGGGCACTCCCTGTGGAGGCCTTGAGGGTC
+
CCCFFFB@BDDDDDDDCDDDDDDDDDDDDDDDDDDDDDDDDEDDDDDDDCDDDDDDDDDDDEDDEDDDDDDDDDBBBDDDDDDDCDCCDDDDDDDDDDDDD
@70X
ATTTGAAGCTGCCATTAAACAAAGAGATGGCATTATAACCCAGCTCACTGCTAATTTACAACAAGCAAGAAGAGAAAAGGATGAGACAATGAGAGAATTTT
+
CCCFFDFFHHHHHJJJIGIJJJIJIJHIJJJJIJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJIJIIIGGIIFHEHFFFFBAEECEEDDDDDDCDDDDDDD
@70Y
TTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCGGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAAC
+
@@CFFFFDHHGFDHE?CGHIIIIIIIIIIIIIIDGIIIIIIGIHCIIIIIIEGIIF/=DDB?BDDDDDDDDDDDCDDDDDDDDDDDBDBDDCCCDDDDDDD
@70Z
GAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJHHHFFFFFDEEEEEEDDDDDDDDDDDDDDDDDDDDDDDDDDEDDDDDD
@710
TGATTATCGAATACGTTGTGAAGAGTTAGAAAAGGAGATCTCTGAACTTCGGCAACAGAATGATGAACTGACCACTTTGGCAGATGAAGCTCAGTCTCTG
+
@@@ADDDDFDFFHIGBDGHHIJGEGAEHHHIIGHGIIGGHGIIIIIJGIIJJJJJIGJIJGIGGDGHEHHFHFFFFEDEECCBDDCCCCDDDDDCCDDCC
@711
GGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJIJJJJJJJJJJJJJIJJJJJJIJJJJJJJJJJJJJJJIJJJHHHHHFFFFFFEEDDDDDDDDDDDDEDDDDDDD
@712
CCTCCTCCTAAAAAGACGAAGAAAAATAATAGCAGCAACAGCAATGTGAGCAAGAAGGAGCCAGCGCCCATGAAGAGCAAGCCCCCTCCCACGTATGAGTC
+
CCCFFFFFHHHHHJJIJJJIIJJJJJJJJJJJJJJJJJIIJJJIJJFHIJIJIIJJJJIJJJHHGFFDDDDDDDDDDCDDDDDDDDDDDDDDDADDDDDCC
@713
GGGCTGAGGTGCAGACATCATTCCCTGCCCTGTAAGGCACTTAGAGCCCTGAAAAAGAGACCCATCATGGGACCAAAGACAATGAGCCCCGACGTTTCCTG
+
9(-28@((2)(2.))2<=@?):44)226=>?(.)21))(.0).)).0(<)(90)/(<()..5(()..))66.96(((..(-,(-(-,(,,7'&)&((++5(
@714
CCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGG
+
@@@D;;DDFFFFFEFEG9:AFACFEFFG<C<??BECFGIIIC?FCEFC7;DF9@=CE>?CFFB?BDDB>A@:;@?@=@@?098A@@@?@@??<@88??A3>
@715
GTGAAATGCCTGGAAAACCGAGTTGCAGTCCTGGAAAATCAAAATAAAACTCTAATAGAAGAGTTAAAAACTTTGAAGGATCTTTATTCCAATAAAAGTGT
+
?@@=BDDBHDADHGHEGDEGBH<?FCGDHGD>FDGHEAHIGIIGGGGIGIIEHCCEHIGIIIIHGIGGCDECHFA??@?D>CCCCA@CACDCCCCCCA,5>
@716
CGGCGAGGATCACTTCAGCTCTGGCAGTTTTTGGTAGCTCTTCTGGATGACCCTTCAAATTCTCATTTTATTGCCTGGACTGGTCGAGGCATGGAATTTA
+
C@@DFFFFHHHHGGHIBGHGIIIJJJICGIIJIIHIJJJJJJIIHJIJJIJIJJJIIJHHHFFHHFFFFFFFEDECCDADCBDACDDBDDDDDDDDDDDC
@717
CAACACGTTTGAAATGAATGGCAAAGCTCTCCTGCTGCTGACCAAAGAGGACTTTCGCTATCGATCTCCTCATTCAGGTGATGTGCTCTATGAACTCCTTC
+
@@@FFFFFGHGHHJIJIIJGIIIJDFGIGGIIGIHIJIJGIEIIIGG@FG;FHGIIGFIJJJIGCHH>@DEF@CDEDD;AECC>CACCCDDECDDDDDDDD
@718
CTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGAATGGCACTGGTGCTTATGATACCACCACT
+
???D??DD<A+A:<<<AE3:?<2C><C<9EE<EEE>BD*BBDDIIDB5@ACECE4=(6(;;@(.;;.6;9>''95><,55>5:>3:4>AA>>AA>:>8<?>
@719
TCTTTGGAGCCGCATCACAATACTGGACCTCCCCCACGGGGGGAATCTACCCCAACCCCAACGTCCCCCGCCATCCTAACACCCACGTGCCTTCACACTT
+
@CCFFFDDHHHHHFGIJIJJIJJIIIJIJJIIJIGIJJJGIFDDDDCCDDDDBDDBDDBDBB?BBDDDDBDDDBDDDDDDDDDDDDD??<BDDC@@CCDD
@71A
CCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCAT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJIJJJJJJJJIJHHFFFFDCEEEEFEEDDDDDDDDDDDDDDDDDDDDDE
@71B
CCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACT
+
CCCFFFFFHHHHHJIIJJJJJJJJIJJJJJJIJJJJIIIJJIJJJJJJJIJJJJJJJIIJJJIJJJIHHHHHFFFFFEDDEDBDDDDDDDDDDDDD
@71C
CTGGGACTCCCAAAGCAACATCTTCTCACCAGGGCCTTGGAAGCACTTTGCCTAGAAGGGGAACAAGGAATGCCATCGTTCCGAGAGAAACTTCTGTTAGT
+
?;;DB;A+ACC3DDEEA:C33A<+?9AAA;CEE:?8?<B?9?DDBD*?B4?B==BA7)(-;5'5(..(.37.;;6.((,55(''88=03934::44+4::>
@71D
CTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATG
+
?8??DD8DHDC=??FAAAFHIGBH;::?BGH<?*?@DAHIEDDFGGDEAC?HAAEDC@BC>;>>ACCCCCCBBC@BBBBBBBCC:CC??C???@BCC>AC@
@71E
CTGGACAACATGATCCGCCGCCTCTCCCCGGCTGAGAGAGCTCAGGGACCCAGGCCGCACCAGGAGAACAACCACCAGGAGTCCTACCCTCTGTCAGTGTC
+
@C@FDEFFHFHHDAGIJIJJIIGJGIIJJGIJIIIJIJJGIFHHIHHHHFFFDDDDBBDDDDBDBDB?CCDDBDDDB?B?B3>CCDDDDCDCCCDDDCC@C
@71F
AAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCAC
+
CCCFFFFBDHGHDIJJEHEIGEGIFHIIGIEDHGIGEIJGGGIIIIJJJGHGFHFDBEFECEEEEEEDDDBDDDDDDDDBBCCC@AACCDDCDDDDDDDDB
@71G
CCAGCGCCCATGAAGAGCAAGCCCCCTCCCACGTATGAGTCGGAGGAAGAGGACAAGTGCAAGCCTATGTCCTATGAGGAGAAGCGGCAGCTCAGCTTGG
+
CCCFFFFFGHHHGJFJGIJHJJJIJJJJJJIJIHHIJGEHGIIIIJHHHHFFFFEDEEDDDDDDDDCDDEFEDCDDCDDDDDDDDDDDBDBDDDDDDDDD
@71H
AGCCAGCGCCCATGAAGAGCAAGCCCCCTCCCACGTATGAGTCGGAGGAAGAGGACAAGTGCAAGCCTATGTCCTATGAGGAGAAGCGGCAGCTCAGCTTG
+
CCCFFFFFHHHHHJJJJJIJJJJJJJJJJJIJJJJHIIJGIIJIJEHHHHFFFFEDEDDDDCDDDDDDDDDDFFDDDDDDDDDDDDDDDDCDCDDDDDDDD
@71I
GGCAAGAAGGCTTCCTGGCTCATCCCAGCAGAACAGAAGGCTGTATGTTTGAAAAGGGCCCCAGGCAGTTTTATGATGACACCTGTGTTGTCCCAGAAAA
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJIHHHHFFFFFEEEEEEEDDDDDDCDDDDDDDDDDDDDD
@71J
CACACCATCCAGCACGCCAGTGTCCCCACTGCATCATGCATCTCCAAACTCAACTCATACACCGAAACCTGACCGGGCCTTCCCAGCTCACCTCCCTCCAT
+
CCCFFFFFGHFHHJJIJGGHEGFHHJJIJJJJIJJJJJIIIIIIIJIIJIJIIJGIIJJJGIJJGHFFFEEEEEDDDDDDDDDDCCDCDCDDDBBDCDDDD
@71K
CTCAGACAAGAAGAAAAAGAAAAGGGTACACTTGAACAAGAAGTTCAAGAATTACAACTTAAAACAGAATTGTTAGAAAAACAGATGAAGGAAAAAGAGA
+
CCCFFFFFHHHGHJJJIJJJJJJJJJBEHIJJIIJJJJJIIJJGIJJJIJJJJJJJJJJIJJJJGIGIJHHHEHHGFFFFFDDEEEDDDDDDDDDDDDDD
@71L
AGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACC
+
8+++4?D:F?AC??@EFB:D9?;B???DBDD8?B98B<8<B17@=@>@ADFIA??;7?@;57;?(;AC:>?BB@B2:>?<??BB3>3:<?B::>A@>A:@B
@71M
GCCACACGACAGGGGTAACCTGGGGCTGGAGGGAAGCTGTACTGTCCCACCTAACGTTGCAACTGGGAGACTTCCGGGGGCCTCACTGCTCCTAGAGCCCT
+
@@@FFFFDDFHFDGG@CEEGGIGIJIIGIIEIJIIGGGGCDHIFIJJJJHBEHDFBC>?AEEDDDDDD@/<@C@>=BDDBB>B?>B@A>:@>?CCCCCAD<
@71N
TTTTGGTCTAGCTACAGTGAAATCTCGATGGAGTGGGTCCCATCAGTTTGAACAGTTGTCTGGATCCATTTTGTGGATGGCACCAGAAGTCATCAGAATGC
+
?@@DD<DDHF<BACBEF<AACC:CD:A+???*?FFDGHB@DFB?DDHGHI@G8?B=B>=)8BCFA@>;CHG;C.=C=ADB?3>;A?AC>;>;@(;5A:@A5
@71O
TTGAAATCGACTTTGAGACCCTGAAGCCGTCCACACTGCGTGAGCTGGAGCGCTATGTCACCTCCTGTTTGCGGAAGAAAAGGAAACCTCAAGCTGAGAA
+
CCCFFFFFHHHHHIJJJJJJJJJJJJJJJJJJIJJJJJJJGHJJIJJJIJJJIHHFFFFFFFDEDEDDDDDCDDDDBDDDDDBDDDDDDDDDDCCDCDCC
@71P
GCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGGGCTTATGATACCACCACTGCTACAGTC
+
@<@D?B??AC3A2<FDEF@FCEE@G>FGB??EGIFF;?BFEFFFDA=@CFFBC7@7?C?EDD@A@AC5@BAB(388<ABABDE>>@BB?BBA@BABB>4@
@71Q
CTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGC
+
CCCFFFFFHHGHHJJJJJJJJJJJJJJIJJJGJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJHHHHFFFFFFEEEEEEEDDDDDDDDDDDDDDDDDD
@71R
CCGACGTTGGGGCATTCAGAAAAACAGGCCAGCTATGAACTATGATAAACTTAGCCGTTCACTCCGCTATTACTATGAGAAAGGAATTATGCAAAAGGTGG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJIJJIJJIJJJJJHHHHHFFFFDDDDDEDDEEDDDDDDDDDDDCDEDDEDDDDD>CB
@71S
GCTTATCCATCCCTATTACTTTTTTAAATGGCATTAGTTCTGTGTGCTATTGGTGTTTATTTGCATCCACCTGTCCAGTTGCTCTGCTGTCTTGTGTTTTT
+
CCCFFFFFHDHHHJJJJJJJJJJIJJJJJJIJJJJJJHIJJJFGHIJIIIJJJDHHHGHJGIJJJJIJGGGJJHGHHFHFFFFFFEDEEECCCDCCCCDDB
@71T
CATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCT
+
?8;=;DBDF;C<A:2CGF<ECBFFF@FCEEFF@FBFGF@?FGF?DGFFB>FC@FDFEFF@F/AEBA77=@?DB:BBBBA@AABB3;>A>A>:5<@B?B<<9
@71U
CACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGAT
+
@@@FFDFBFBHHH;GGHBHHIEHGIEECAHEHGIHF*?DGGII@DB?CGFHIGCCFHG@AHGEEEHD?@BC;@CA?CCBC@>CDCCCC@BBCCBB?@ACC:
@71V
CGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCG
+
CCCFFFFFGHHHHIIIIIIIFHHIJJJIJEIJJJJJIJJJJJIJJHHHFFFFEEEEEEDDDDCDDDDDDDDCDDDDDDDDDDDDBDDDDD@CDEDDDDDDD
@71W
TTTATTGCCTGGACTGGTCGAGGCATGGAATTTAAACTGATTGAGCCTGAAGAGGTGGCCCGACGTTGGGGCATTCAGAAAAACAGGCCAGCTATGAACT
+
CCCFFFFFHHHHHJJJJGIIIJJJJJJJHIIJJIIIIIJGIJIIJJJJJJJJGGI;FHGIIHDDDDDDDDDDDDDDEDDDDDDDBCDDDDDDDDDDDEDD
@71X
GCCGACGATGCCAAGGGAAGGACGTCCTATGTACCAACGCCAGATGTCTGAGCCAAACATCCCCTTCCCACCACAAGGCTTTAAGCAGGAGTACCACGACC
+
C@@DFDDFHHHGHIIIEHCHIJIIHIIHIJJJIIGGFIGIJJICHIDE@EHHGFFFFFEEEED@CDDDCDBBD?ABBDDCDDDDCDCDDDD9>@CCC@<>B
@71Y
CCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTAT
+
@@?DDDD?DFHHA>DEFGFG>?EDHCHB<?9@D>?<<>DEHHCDHC?DEHGC@8BBFHCHGIIIIGID>AAEEDDD@>C>;;;>>@CC=AC=B@<5<9<B3
@71Z
CTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTT
+
@@@DDADDFBHHHIEE@9EH::E@F<CH9CCEEFHI?F?BFD=3DA9D@FCADACCHII<GC@E45943;>;>->;;@AACCA>3,((,99<??C@AC?4>
@720
CAGGACGCGAATGAAAACACTTGGGAGAAGGGACTCGAGCGGGGATTGGGAGCTTCCGGATGGGCAGATTACAGTGGGACAAAGAATTGGATCTGGATCAT
+
(0;?(((<3-((:.)@)=((=.63((0((:>?((.)733'-''3',,,8/28&(+:(&0&)02:(30+:(++(84686:(+8;39<<=5(62:46:<:<8:
@721
CGCCGCCAGCTTTCTGAACCCTGTAACTCCTTTCCTCCTTTGCCGACGATGCCAAGGGAAGGACGTCCTATGTACCAACGCCAGATGTCTGAGCCAAACAT
+
?;<DDDDDDDDDDIIAEIE8CEEE<E?D>DDEEDDECADEDAE<DDAAADC=CDDC@<?;>=6@>????AAA>B>AAA<<;>9;?AAAA:::A>AA>???A
@722
TTTCATACTTACTATTATAGTTGGAATATTTCTGGTTGTTACAATCCCACTGACCTTTGTCTGGCATAGAAGATTAAAGAATCAAAAAAGTGCCAAGGA
+
C@@FFDFFHHGHHJIJJJIHJIIIJIJJJJIJJJJHGGIGIAGGIIIJJJJJIGIJIJJIDEIJJIGHGIHIDHGEHHDGHHHHHHFFDB5>@ACDBDA
@723
CAAAGAAAAAGGAGAAAGACAAGAAGGAAAAGAAAAAAGAAAAGCACAAAAGGAAAGAGGAAGTGGAAGAGAATAAAAAAAGCAAAGCCAAGGAACCTCCT
+
???DDAD>;DA+<<+AB?CECE@A;9?;BA?C?C?BD@:;DDD9(=3=C6@C7AAC9?AAAD9;>;A>6>;;>;>A>>:=5&(933(9>?>8(8A8<<>?<
@724
TTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGCGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGATCAAC
+
;?1;B4DAD4?C:32))11@AAFE@EA<4?D3::C3BDB@>DDEIEAD?DE;BB@)8)))--'''.,,=33(,;355(:>:?=?(98(++((43>((+4>3
@725
AGCTGCCACTCCATTTATATGAGGCAAGAAGGCTTCCTGGCTCATCCCAGCAGAACAGAAGGCTGTATGTTTGAAAAGGGCCCCAGGCAGTTTTATGATG
+
@CCFFFFFGHHHGIJBHIJIGGIIIJJIIIJJJJJJIIJJJJJJIJJJIJJJIIIGGIJIJIJFIHGHIFEEHHHFFFFDDDDDDDBDDDCDEDDDCDED
@726
CCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCC
+
@@<D;?DDHHDHDGGIIIBGEAECGIEGGHHGDB?@FGC>FFH?<DGIGIG9FCHIIDEGAEEHEDFBDF;ACAC=ACCCD@CCCCBBBBBBBBCCCA@C?
@727
TGGAATATTTCTGGTTGTTACAATCCCACTGACCTTTGTCTGGCATAGAAGATTAAAGAATCAAAAAAGTGCCAAGGAAGGGGTGACAGTGCTTATAAACG
+
@?@DDDDEDHHHHIIGIIIIHIIIEGDGEEHFGGHHIIGGH>F>GDH><D@;@BEDHHCCEBGCFAFHGHHHFFEDD?B@;=@,3<AACDCA>CCC@@AC?
@728
ACACGCCCTGTCCCTCCGCACCAACGGCTACTGCATAAGGTCTGCGGGAGGGATGGGCATCAGGCTCGGGGGCCTAGGGGGAAAGATCGGTGTAGGGG
+
1+++2)20)<2+222<+)?21)15:))::A;//**0))).))..)'-',',,',(((,,(,((,((+&0-9&&)+++(20&&)+((+((&((&(((+)
@729
GCGGCAGCTCAGCTTGGACATCAACAAGCTCCCCGGCGAGAAGCTGGGCCGCGTGGTGCACATCATCCAGTCACGGGAGCCCTCCCTGAAGAATTCCAACC
+
CCCFFFFFHHHHHIJJJJJJJJJJJJJJIJJJJJJJJJJIHHHHFFFFDDBDD?BD<?CCDDDDDDDDDDDDDCDDDDDDDDCDDDDDDDCDDDDDDEDAD
@72A
ACGAGCAATAGTTGTGACATTAACTAAGGTGATGTGCTCTATGAACTCCTTCAGCATATTCTGAAGCAGAGGAAACCTCGGATTCTTTTTTCACCATTCTT
+
@@@FFFFFHHHDHJHIIJJJJJJJJJIJJFHHJJIJJJJIJJJJJJIJJJJJIJJJJIIIJJJJJJJIIJJJIGIJHHHHFDFDDEEEEDDDDDDDDDEEE
@72B
CACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAAT
+
???DBADD;DDAD>B>CA?E<<;A<4?E@AECDA8;CD??DBDDDDDDD>BAB;BCCC@@A/5<D>3@@@>>(;;=559<<2>>>:+(:>3(:>(+9<>A>
@72C
TTTTGATGAAAATTGGCTAAACAGAATCAAAACTGAAGTAGGAGATAATTGGCGGCTAAAGATAAGCATTTTAAAGAAAATTTTAAAAGGAATCTTGGATT
+
=114A22=D?DDDEID;CF@:FEEFCBBF9C@?@?C@CD<@D9?8000?9B?*7-';C=.77.7?AAD:AA>63.6;??;5;>>>AA>:<9A:5:>34:44
@72D
GGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGC
+
@@@DFFFFGGHHHJJIJJJJIBGIJIJIHGGIJJJGIHEGGGIJEFGGIIIJIJJEIJIDHHHGHFFFFEEEDEDEDDDDDDDDDDDDDDDD:ACDDDDCC
@72E
CCTGGGTCCTGGAGAAACCCTAGTACCTGGGGATACGGAGAGCAGTGTGATTCCCTGTGGAGGCACAGTTGCGGCAGCTGCCCTAGAAAAGGGAAACTATT
+
>=+??7?ABBBBBAB>=;=A77>+<+?==A1:):=AAAAA);==A8<8)=>>AA>A7>7=A;1>A9>9>?>>/39,8;((:;=:3+33:;=0(+(88:?:8
@72F
TCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATG
+
CCCFFFFFHHHHHJJJJJJJJJIJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJIJJJJJJJJJJGHHHHHFFFFFEDEEEDDDBDDDDDDDDDDDDDDD
@72G
TGGGGACAGTCGAAGAACTTCAGAAGAGAAATCATAAAGACAGCCAGTTCGAAACTGATATAGTACAACGAATGGAACAAGAAACACAAAGAAAGGTAGA
+
;:=:DD:D;2<<C<<@+2AFAF9F@EI8??D@*1C9:D9D??9DB??/?*-8=C;@@;A=7@=.77?D)=DD27;>;666(;;?;5(9855(5=3(+4(4
@72H
ACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGT
+
C@BFFFFFHHHHHJJJJJJIJIJJJJHIIJIIJJJJJJJJJJJJJJJGGIJIJIJJJIIIJIHHHHHFFFFFFECDDDDDDDD@BBDBDCDCDDEDDC39>
@72I
CAGATCCGAACTACACCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATGACATCTCCTGTGACTCTCACCTCTCAGACAACTAAGACAGATGACCCCC
+
CCCFFFFFHHHHHJJJJJJJJJJJIJJJJJJIJJJJJJJJJIIIJJBFHIJJJJJJIJJJJJJJJJJIJIJHHHGHFFFFFEDEEDDCDDDDDDDDDDDD
@72J
TTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGC
+
@C@FDFFDHGHGHGHIGIEIJIFGEGHEHGIGGIJJJI@GGHEDHFDFEEHGIIIGHHICCCGEEDEEFFFFFCEACCEEDB@;ACC?CCDCDBDC>?BDD
@72K
CAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGG
+
CCCFFFFFHFHHHJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHGHHHHFFFDDEDDDDDDDDDEDDDDDDDDDDD
@72L
TGGAATTTAAACTGATTGAGCCTGAAGAGGTGGCCCGACGTTGGGGCATTCAGAAAAACAGGCCAGCTATGAACTATGATAAACTTAGCCGTTCACTCCGC
+
CCCFFFFFHHHHHIJJJIJJJJJJJJJIIIFHJJJJJJJIIJJJJJJJJJJJHHHHHHFFFDDDDDDDDDDDEDDDDDDEEDDDDDDDDDDDDDDDDDDDD
@72M
GGCTGAAAATGAGTTTTCTTTAAGGCCAATTGACAGCAACACGTTTGAAATGAATGGCAAAGCTCTCCTGCTGCTGACCAAAGAGGACTTTCGCTATCGAT
+
@<@DFDFFHHFBHGHIEIJEGIIIIGGIJIIGI@HHGIGEGGGHIIIHJJJJIJJJJIJJGGIJJJCHIGCHCHFFFBDFFDEACD;?CDDCB?BDDDDBD
@72N
CAAGAGTAATAACATATTTCTTCATGAAGACCTCACAGTAAAAATAGGTGATTTTGGTCTAGCTACAGAGAAATCTCGATGGAGTGGGTCCCATCAGTTTG
+
CCCFFFDDHHHHHJJJJJIIJJJJJJIJJIIJIJJJJJJIJJJJJJJIFGIJJJJJJFHIJJJJJIJIJJJJJJIIJJIGHHHF@DFFCEDDDDDDD@CDD
@72O
CTTACCATCTGTAACAAAGGAATCATCACTTAGAGCAACTCAACCAAGTGAAAATGATAAACTTCAGAAAGAACTCAATGTACTTAAATCAGAACAGAATG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHIJJJJIJJJJJJJJJJJJJJJJJJJJJHHHHHHHFFFFFFFEEEEEEDDDDD
@72P
GCCACAAGTGGGAATGAGGCCCTCCAACCCCCCCACACCATCCAGCACGCCAGTGTCCCCACTGCATCATGCATCTCCAAACTCAACTCATACACCGAAAC
+
@CCDFFDFFDDDDGIIIHGGGIGIIGHJFHIIGJJJEIIGIGIHEEFF<BB<A;@ACDD?ABA>AACDCCACADC(>@CCCBAA>CDCCCC@C>CCBDDDD
@72Q
CAAGAAGGAAAAGAAAAAAGAAAAGCACAAAAGGAAAGAGGAAGTGGAAGAGAATAAAAAAAGCAAAGCCAAGGAACCTCCTCCTAAAAAGACGAAGAAA
+
CCCFFFFFGHHHHJJJJJJJJJJJJJJJIJJJJJJJJJJIJJJJEHIIJIIGHHGJJJHHFDDDDDDCDDDDDDDDDDDDDDDDDDDDDDDBCBDDDDDD
@72R
CTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGAC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJIJJIJJJJJJJJJJJJJGIJJIJJJJJJJJJJJJHHHHHFFFFEEDDDDDDDDDDDDEDEEEEEDDD
@72S
CTGCTTGACTGTCACTTGTGTTAATACACGTAGCCTTCGTTGTAGGGGTGGGGGTTGCAGCAGCCCCCTTCCGGCATGTAG
+
C@CFFFDEHHHHHIJJJJFGDGHIJJJIJIJJJJIIJJIJGIGIIJJJ?DGGJG=AACCDDDBDBBDDDDDDDB>>BDCCD
@72T
ACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCT
+
@@@DDDDADHHFFIFIADEGHHAFCEHEGFG@GHEIGIIDEHGGIII>AFGEIIDIGIIGHIIIICG@E9CCDEC>BBB?ACCCCCCCC<AAB?B:CA>3
@72U
GTGACAGTTCGACTTATGACTCTGATGAGGATCGAGCCCAGCAACAGGCTGAGCTCCAGGAGTAGTTCAAGGCCGTGTACGAGCAGCTTGCATCCCTCTCT
+
=:+<<,??><+@=7++2+333<++322+2+***)1)1?)?A>))0(9A(.8(6))..)7.65)7))))).).6(',,,(-((8/;=(8:79(((31(+3((
@72V
CTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTAT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJIJJHGIJJJJJIJHHFHHHFFFFFFEEEEDDDDDDDDDDDEDDDDDDDDDDDDDDDDDDDDDD
@72W
CCACCCGAAGCCATCCAGCCCCCGGCAGGAGAGCACACGCGTGATCCAGCTGATGCCCAGCCCCATCATGCACCCTCTGATCCTGAACCCCCGGCACTCCG
+
@@CFFFFFHHHHHJJJEHIIJJJJIJIJGIIJJIJGIIIGFFDDEEDDDDDCDCCDDDD@BDDDBCDCDCDDDCDBBCDDEDDDDDDDDDDDDDDBDCCCB
@72X
GAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCC
+
@@@DDDDDH@FDDFHFGIJJIGIEGHFBGDGEFEHGIHGEGIIEHGEHJGHGHHCHEDDEBEEC@;C?B=@BDDDBBBDDDDDDCEDDCDDDDBDBDDDDD
@72Y
TGAAGGAGTATGTTGACATCATGGAATGGCTGGTGGGGACTCACTTGGCCACTGGGGTGGCAGATGGAAAACAAGAGGAAGAAGGGCAGCAGCGGGGGG
+
:8+B:DD:2A?<D4,A:<33+33<33:C3FF;))11C)B600*//BDE38B(.8((-'''(),((6@;;A>3=?95(,55<?9380(+0+<2(&)&&55
@72Z
CTTGGAACGGATGCATTTCATTCACAGGGATCTGGCAGCTAGAAATTGCCTTGTTTCCGTGAAAGACTATACCAGTCCACGGATAGTGAAGATTGGAGACT
+
???A=D>B88D8?EEEB>:C:3<CD<BD?C;EE?D@;DDE99?D9DBC<?9D?8==CDC=;CCEC)=7?;C>>DAAAADA@>3>?>>>ADA<AAA9:5>8>
@730
CTTATTCAAACATCAACAACAGGGACCAGATAATTTTTATGGTGGGACGAGGATACCTGTCTCCAGATCTCAGTAAGGTACGGAGTAACTGTCCAAAAGCC
+
@@@BBDDDFFFDHFFGGGGHHIIIEEFEEGGGHEGDEEGEHI?FHG=?FABGE@ECHCE;AEHEEEC>@>CC@;>@CC(55>@8;(5::;>44:@C>A?28
@731
GTTTTATGATGACACCTGTGTTGTCCCAGAAAAATTCGATGGAGACATCAAACAAGAGCCAGGAATGTATCGGGAAGGACCCACATACCAACGGCGAGGAT
+
CBCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJIJIJJJJJIJJJJJJJIJIEHHHFFDDDDDDDDDDDDDDDDDDDDDDDDDC
@732
TGAAAAGTCACATAATTCTTGGGAAAATTCAGATGATAGCCGTAATAAATTGTCGAAAATACCTTCAACACCCAAATTAATACCAAAAGTTACCAAAACTG
+
8:1BBBDA22C?FFBE<?HEE@;FBGBDFIBH<FC<FHIIIFIGI;BBGBG<?DDHHHI:=C;87==@D@E?A56;?CACC;C@;;=@>->;@C::<?<>>
@733
CATCATCCAGTCACGGGAGCCCTCCCTGAAGAATTCCAACCCCGACGAGATTGAAATCGACTTTGAGACCCTGAAGCCGTCCACACTGCGTGAGCTGGAGC
+
CCCFFFFFHHHHHJJJIIJJJJJJJJJJJJJIJJJJJJJJJJJIJJJJHHFFFFFFEEDEDDDDDDDDDDDDDDDCCDDBBDDDDDDDCD>BDDDDDDDDC
@734
GAAGACCTTGGTGATTTAAGGCGGCAGGTTAAACTCTTAGAAGAGAAGAATACCATGTATATGCAGAATACTGTCAGTCTAGAGGAAGAGTTAAGAAAGGC
+
<@@DDDBDHDD?<EFFDFIGCHEAHHBHHBFHEHIEGHHFHIIGGEIA@D@@EHCEFHEEEEEDDE>CAAAC@>CCA@@@AACCBBB@BBCACD@AA?@BB
@735
GGAAGACCTGGCTTACATGAACCACATCATGGTCTCTGTCTCCCCGCCTGAAGAGCACGCCATGCCCATTGGGAGAATAGCAGACTGTAGACTGCTTTGGG
+
CCCFFFFFHHHHHJJJJIIIIIJJJJEIIGIIEFHIIIIHHGGIIIJIGIFIHIJJJIIIHHHHFFFFFDDECCBBDCDCCCDDDCDADADCDCCDDDDDD
@736
GGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACAC
+
@<?DDDDDBBFFFGEGIB>EEB><FHIFBDCGEHII@GDFHC;B=D>FDDC<=BF==@CGGFADCGHIF:7=;@@@DECBCCCBCCA@C>>;(;:@@>@?
@737
AACTGATGGCGGGAGGCGACCTTCTTACTTATTTGCGTAAAGCCCGGATGGCAACGATTTATGGCCCTTTACTCACCTTGGTTGACCTTGTAGACCTGAGG
+
-(;-@?@<))=(>-:=(-'---)))6))<.=?8)))9,,(.;<<7,',80+2+(80(+8(+++++89<(82+(+(+8<=:(8:-(8;<2(++(((+(+(5(
@738
TTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAAC
+
CCCFFFFFHBBFHIIIGIGIGEHGJJI@FFHIGIIIFHGIGIJJIIIIIJJIIJJIIIIJJIJJJHHFDDDDEDCDDDDDDDDDDDDCCCCCDDDDACDDC
@739
GTGTAACTGAGTATCAGGAAGGCTGCCAGGGACTGGGCTCCAGGGGCAACATTTCCCTGGGTCCTGGAGAAACCCTAGTACCTGGGGATACGGAGAGCAGT
+
<?@DDDDFFHHCFHIJIIJJJJJIIJJJJIJAGFGIIJJIIIJJIJGJJIJIJJJIJ@EEIAEHEFFFB;ACCEDDDDACCDACBDB<BDDDDBBDDDDDC
@73A
TGTGAAATGCCTGGAAAACCGAGTTGCAGTCCTGGAAAATCAAAATAAAACTCTAATAGAAGAGTTAAAAACTTTGAAGGATCTTTATTCCAATAAAAGTG
+
@@@DFDFBFDHHHAHIBGEFGBEHEFGII?C?FFAGIC@?FFHDDEEHGHBG=CFDBFGFGHCFHGECGAEEECHECDCE@>@AC;>;@A;>@CDCDACC>
@73B
GATTCCTCCTGAGCGGCTCTTCAACCTTCTGAAGACCGGCCACCGGATGGAGAGGCCAGACAACTGCAGCGAGGAGATGTACCGCCTGATGCTGCAATGCT
+
<@@DDDDDHDFHFHIIIGI3:EDGGGGDGGEGI9FGD@6AGGFCB@EHEEE>CA?CBB=5<?(9::>@CC@9>@9<A>+44@C@B@9A3@A::>>>A@CCC
@73C
GGGCCCTCCGTTATTACTATGATAAAAACATTATGACCAAAGTGCACGGCAAAAGATATGCTTACAAATTTGACTTCCACGGCATTGCCCAGGCTCTGC
+
@@@FFFFFHHHHHJJJJJJJJJJJJJIJJJIJJJJJJJJJJIFHHIJJJJJJJJJIJJJJJJJHGHHHGFFFFFFFEEEEDCDDBDDDDDDDCDDDDDD
@73D
TATGACCAAAGTGCACGGCAAAAGATATGCTTACAAATTTGACTTCCACGGCATTGCCCAGGCTCTGCAGCCACATCCGACCGAGTCGTCCATGTACAAGT
+
<@@DFDDFFHFAFHGIIBGGGGGIHGHGIHGGIGHIGGIIJDGGIGIIEIJDIIIHGJIEGFHGFFDEDCCACCECCCBBBB@@>@DB8?@BDCCDEEDDA
@73E
CCTAGAGGGAAAGCGAGAGGGAGACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGC
+
@CBFFFFFHHGHHJJHJIJIJEHGIJJIJJIIJIIIIJJJJHIHHEFEFEDDDDDDDDDDDDDDDDDDDDDDBDDDDDEDDDDDCDDDDDDB@DCCDDDDB
@73F
CCAGATAGCAGCTACCCCATGGACCACAGATTTCGCCGCCAGCTTTCTGAACCCTGTAACTCCTTTCCTCCTTTGCCGACGATGCCAAGGGAAGGACGTCC
+
CC@FFFFFHHHGFIJJFIJJJJ@GHJJJJJIJJIIJJIJJGJJIIIJJJIIJJJJHEHHHHHFFFFFFCDDEEEDDDDBBDDDDDDDDDDDDBDDBDDB@B
@73G
CAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTGAGTTGCTAAGAGAGAAAACCAAATAAGAATGAATGTGTTTAGAGT
+
CCCFFFFFHHHHHJJJJJJJJJJIJJJJJJJIJJJJJJJJJJJJJJJJJJJJIJCHEHHGJJHHHHHHFFDFEEEDDDDDDDDDDDDDDED>CCCDCDCD:
@73H
ATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCA
+
@@<BDDDDHFDH?GD:E<C;?E@@HGG>8@?@DE;?@AHHG?D<DBFCHGGIDHAEFFDE=;=ACCCC@CB>>AC@;5>CCBBCA<5BBBBBCC@ACBBC
@73I
GAAAGATTGATTTTCTTAGACTCCATTAAGTCCAAATCCAAAGACTCTGTGTGGGAAAAAGAAATAGAAATACTTATAGAGGAAAATGAGGACCTCAAAC
+
@@@FDFDEF?FHDHCHGIIGIIIIGFHIIE<ABHHBHGIEHGGDGEHIIIIDFHGGHIIIIIIIIIIIIGHGIIIGHHFGHFFFEFCCCEC@BDCCDCCD
@73J
CTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTC
+
CCCFFFFFHHHHHJJJJJJJJJJJHIJJJJJJJJIIJJJJIJJJJIJJJJJJJJJJJJJJJJIIJJHHHFFDDDDDDDDDDDDDDDDDDDDDDDCDDDD>C
@73K
GTGGAGGCACAGTTGCGGCAGCTGCCCTAGAAAAGAGAAACTATTGCAGCTTGCCAGGACCTTTGAGGGCCAACAGCCCACCCTTGAGGTCCAAAGAAAAT
+
C@BFFFFFHHHHHIJIGGHIGIIJIJIIIHGIIJJGHGIIIJGJIIIIIJGIIIIHGHFFFFFFCEDEDDBDDDBDDDDDDDDDDCCCD99CCDDDDDDDC
@73L
CCAGAAGCCCTTTTCTCCATGGCCTTTCCAGATAATCAGCGTCCACTGCTGAAGACAGACATGGAACGTCACATCAACGAGGAGGACACAGTGCCTCTTTC
+
???DDD8DDDDD?A<EEE><F;+C+9CCBEEE?EEIADDD::BD?D*BDDE><BCDCC=A;AECDC@8===C;ADDA>@<??8??=?=<92:>A>>4>>A>
@73M
CTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTC
+
CCCFFFFFHHHHHJJIJIJJJJIIJJJJJJJJIJJJJJJJJJJJJJJJIIJJAEHHHHFFFFFFFEEEDDDDACDDDDDDBDBDDDDDDDDDDDDDDDDDD
@73N
AGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGC
+
?<@DDDDDHHHHHIGGGGGEIGEFGEHIIHIGHGGHEDGIIJIGIGIGIIIHIIC@GGIIIJJJFIIIGFHEHFFFFFEC@C>@C??=BBDDDDDBDCCD
@73O
CCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTT
+
CCCFFFFFHHHHHJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHHHFFFFDDEEDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDD<B
@73P
CCCAAATTCTCGCCTCTATTGAGCTGCTGGCCCGCTCATTGCCAAAAATTCACCGCAGTGCATCAGAACCCTCCTTGAATCGGGCTGGTTTCCAAACAG
+
CCCFFDFFHHGHHJIJJEHHCGGHHIIJF<GHIGIGIIGIGHIJJGGIJJJEHIAGEHEFFFFFFCCEDDDBDDDDDDDDDBBDDDBDACBCDEDDDDC
@73Q
CTGAATGTTCATTCTTATGACCCCCAAGGAGAAGGCAGGGAGGATCCTGATCTTTCCAAGCCTAAAAACCTTGCTCCTTTACAAGAGAGTCAGGAGTCTT
+
>7+?7<<2@7<<<,2@B?AC<<?CC8AC7)1?=A5A?504)).77=;4/.8/.))/8.))(;=7AA>;5=7>(>36>5=5;>5=:39(,;5,,,++9?:;
@73R
CCGCCCTCGCCCGAGCCAGCCCTCCTCCCTGGCCATGCTGGACCTTCTGCACGTGGCTCGGGACATTGCCTGTGGCTGTCAGTATTTGGAGGAAAACCACT
+
??@D?DDDFFFFHIBGGGHIIIGEGBFGGIGGHDGIIGIEGI@EHDCAE;?EC;?B>;@>B@2;B@CCCCC>@ACBA?(4>C>4:BD@@(+<2<A?922<>
@73S
CTCCCTTTATTCCAGCTGTCTAACTGACAAGACCTTTCTCTCTTTCTTTCTGCCTCATGCTCTCTCCAACAGGCTTGCAGCCAATTTACTGGAGCAGGGAT
+
@@@DDAD>FFAB8EBB>E+<AIHIIII>EF3CBGG<F<FHGFG@??FECA<D>@D>9D<DDF*8CBB>A@FFD<@C:E:A3;@;;@C>;;>>>=C?=?:,,
@73T
CAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCC
+
@@;BDADDHFHGHIIIIIIIIBHIGGIDIEHIGIIIICGIBFHG@FHGGIIDGHIHDHDF@EDEEECCBBBBCCCBB@CCCCACBBB@CC@CCA@CCCBB
@73U
GTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCC
+
?;:DD?;AD>BF:FGFDC8?FEDGD?FGICHB39??D@B=C@;A;@CG>7??AA??C7;B@C;;;>>C;;8;?=58<15<8<AA>4:4@CA@@>>95@B
@73V
GTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTAC
+
BB@FFFFDFHHHHIJJJIIJIJJEHIIJJHIJIGGIGGIJGIJJIJIJJJJIFH@GGICHGHHHHEEHFDFFEEDDEECDBDBBD?BDDDBD?BACDCEEC
@73W
CAATTGAAAAGAGAAATAAGGTTAATGAAAAACAGAGAAGCTGCTCGAGAATGTCGCAGAAAGAAGAAAGAATATGTGAAATGCCTGGAAAACCGAGTTGC
+
C@CFFFDDHFDBFEGHGHGIJFHIIJJIIJIIJIIIJJJJFGHJJGIIIGIIJFGHHIIGJJJFHEFHFFFFFEEEEFEEDDDDDDDDDDDDDDDDD<@DA
@73X
CAGACTGTGTGAAATGTCTTGCTATACATCATGAAAAAATTAGGATTGCAACCGGACAGATAGCTGCCGTGGATAAAAAAGGAGGGCCACTACAACCCCAC
+
==7AAAA@BABBB<C+,2<A7@4<=,ACBC4A+++<110:?****?*309==(.''54(=A))).))(,9'';=B?;(5',8=()&00(+(+(4:=(5;80
@73Y
CCTGTCTCCAGATCTCAGTAAGGTACGGAGTAACTGTCCAAAAGCCATGAAGAGATTAATGGCAGAGTGCCTCAAAAAGAAAAGAGATGAGAGACCACTCT
+
B@CFDDFFHHHHHJJJJJHJIGICHGGJJI?EGIIE?BFHIEIHGIIIIJIIIJGIGIJIJIIGICHCEGIHFEHHGFFDEEDE?CCCDCCD@BDDDDDDD
@73Z
CCCAGCCCCATCATGCACCCTCTGATCCTGAACCCCCGGCACTCCGTGGATTTCAAACAGTCCAGGCTCTCCGAGGACGGGCTGCATAGGGAAGGGAAGCC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJIJJJJJJJJJIJJJEGHHHHHFFFFFFEEEEDECDBDDDCDBDDDBBDDD@DDDCCCDDCBBDDBDDDD
@740
CTGCAATGATCCCTGTGAATAGACAGCCCCAACAGGACACCAGTGAACTAAGGCCCTCTCAAATGCTGGCCATCGCCAGTCAGATCGCATGGGGTATGGTG
+
(8((-9=<?)=<)<)9)))3)))))).((((((1...7)(((.)))).<)..)9651())8;;).=?))(().)8,3=<-3(-185;;((((2(00:((++
@741
GTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCC
+
;?@DDBD?FF:ADFE@GAFGD@E;CF+CHHG3?FHBFHHFDIID;@D;@FGHGIIIIIIHEH>AHC3.;?BCAABC?=AB@CCCCCECCA@CCA?AC>?@B
@742
GCAGAGGAAAGCAAAAGGAGCAGAAATAAAGACAACAAATGAAGTTGTTTTGGCTGTGGAGTTTCACCCAACAGATGCAAATACCATAATTACATGCGGT
+
B@CFDFFFFFHHHJJIJJHIJIJJJJJJJJJJJJJJJJGGIJIIHGHHIIJIIIIGHIJGGCGIJGHHHHFFFEEEECDDDCDDDDCDDDBD@CDDCDD9
@743
ATTTTGGTCTAGCTACAGAGAAATCTCGATGGAGTGGGTCCCATCAGTTTGAACAGTTGTCTGGATCCATTTTGTGGATGGCACCAGAAGTCATCAGAATG
+
CCCFFFFFHHHGHIJJJJJJIIIJJJJIIJJIIJFHIJDGHHGIJJJIIJGHIIIGHGIBGGIIJIHGJJJJHFHEHFFFFEEEDCDDDC;ADDCCDDDCD
@744
ACCAGATAGCAGCTACCCCATGGACCACAGATTTCGCCGCCAGCTTTCTGAACCCTGTAACTCCTTTCCTCCTTTGCCGACGATGCCAAGGGAAGGACGTC
+
@@CFFDFDHAHHDIIJJEIIJIJJJJJIJIDHIJJIEGGGIIIIIJIIIIIJJIIEHFEEEFFFFFFCE@ACCCCDDDBBBBBDBBCDDDD?AA@B@A@>B
@745
GCTACAGTGAAATCTCGATGGAGTGGGTCCCATCAGTTTGAACAGTTGTCTGGATCCATTTTGTGGATGGCACCAGAAGTCATCAGAATGCAAGATAAAA
+
CCCFFFFFHHHHHJIEGGIJJGIJJJFIJIGIIJJJIIJJJJJJJGIJJJJJIFIIJJJIJJIHGJIIJIJJHFGGFFFEFFECECEECDDDDCDDDDDD
@746
TTGAAATGTTAGAAAAAGAAAAGAATGCTGTGTTAGACAGAATGGCTGAATCACAAGAAGCTGAATTAGAGAGGCTGAGAACACAGCTTCTATTTAGTCAC
+
@@@DDDDDCFDFHIIIBEABEHIGIGGGIGHIHGHIIGHAGHGHGIEHIGIGEAHIIIIGGIGIHGEI@DCEEHHFEEEECAC6???ACCCC@CDDCCCEC
@747
CCTATGTTGACCTTGATCGTCAGCTGAAGAAAACTACAGAGGAACTAAATGAAGCTTTGTCAGCAAAGGAAGAAATTGCTCAAAGATGCCATGAACTGGAT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJIHHHHHFFFFFFEEECEDDDDDDDDDDDDC
@748
CTAAACTAGAAGGTCAAGTAGAATCTTATAAAAAGAAGCTAGAAGACCTTGGTGATTTAAGGCGGCAGGTTAAACTCTTAGAAGAGAAGAATACCATGTAT
+
@@@DD8DD?DAFFHCGIH<?FFEDHFAHBE9FE9EEBEHGHEFHCDDGHBBFFG<BHFD4CC3@;4,9>BCCC:@C;AC:>>;@>?CCCCC:4>@ACC>C@
@749
CCTGGCTCATCCCAGCAGAACAGAAGGCTGTATGTTTGAAAAGGGCCCCAGGCAGTTTTATGATGACACCTGTGTTGTCCCAGAAAAATTCGATGGAGAC
+
CCCFFFFFHHHHHJJJJJJJJJJJJIJJJJGHJIJJJJJJJJJJJJJJJJJJIJJFHIJJJJJJJHHHHHFFDEFDDEEEDDDDDDDDBDDDDEEDCDDD
@74A
CCTCCCACCATTGAACTGTTGCACCGCTCCAGGTCACCTATCACGACAAATCACCGGCCTTCTCCTGACCCCGAGCAGCGGCCCCTCCGGTCCCCCCTGG
+
CCCFFFFFHHHHHJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIIHIIJJJHHFFEECEEEDDDDDDDDDDDDDBDDDDDBDDDDBDDDDDDDDD
@74B
CCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJIJJJJJJJJJJJJJJHHHHHHFFFFFEEEEEEEDDDDDDDDDDDDDDDDD
@74C
CCGAGTCCCACCCGAAGTCATCCAGCCCCCGGCAGGAGAGCACACGCGTGATCCAGCTGATGCCCAGCCCCATCATGCACCCTCTGATCCTGAACCCCCGG
+
C@CFFDEFHHHHHJJJIIIGIIIJIIHIIIGEHGGJHECHI@AHFHFDABDCDCCCCDCDDCCDDDDDDDDDCDCCDCDDDDBBDDDEDDCCDDCDBBB><
@74D
TATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAG
+
=;+44=B;DD;::CEE@EIIBECCFAEE;?BAA@DCDIIE3BDDDEIE==BB@A(5=.7ACD7=CD>>>A@DDAA7?AA>>A??255>>3;;5-552<>
@74E
TGTCAATATTGATGACTTGATTAGAGACCAAGGATTTCGTGGTGATGGAGGATCAACCACAGGTTTGTCTGCTACCCCCCCTGCCTCATTACCTGGCTCAC
+
CC@FFFFFGHHHHJIJIIJJJJIGJIFIJIJJJIJJJIJBHI?DHIJJHHIJIJJJIIICGHJEHIJGEHHHEEEFFFDDDB@BDCCDDEEDDDDDDDCDD
@74F
TGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGC
+
CCCFFFFFHHHHHJJJJJJJJIGJJJJIIJJIHIJIJJJIIGIIIJJIIJIJIGIJJJJJIIIEIHHHHHHFFFFFFEEEEECDDDDDDDDBDDDDDDDD
@74G
ACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCGTCCTACCCTCCT
+
@@@?BDDDB?FHH@?CFA:AEHIIIFGAHFGCFC<FDDFEHDFGHDFB9BFCGEH@GF@GDHGHCG==?E>>BEB;A>>;ACCCCABBB99=BCCB<ABBA
@74H
AGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAAC
+
?@@FFFFFGGHHGIJJGIGIGGIIGHHGIIIJJJGGGHGGIJIJIJJJJJJIEIIIGCHGIIIJIHHFHGHFFFFFFDDECACCBDDDCDBCDDDDBBCDD
@74I
TTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGC
+
@@<DDBFFHDHHGJGGGHDHHHIJIFIFH<GEGGG@C?B;;@BFGGH6@FGGCEI>GIGCCEGCHEACBD@D;B:.;@A>A=BC=>CA9:@@CBBCBBA8?
@74J
GGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAAT
+
CCCFFFFFHHHHHJJJJJJJHJIJJJJJIJJJJJJJJJJJJJIJJJJJJJJJJJJJHIJJJJIJJHHHFFFFFEEEEEDDDDDDDDDDDDDDDDDDDEDE
@74K
CCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAAC
+
CCCFFFFFHHHHHJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJIJJJJJJIIJJJJHGHFFFFFFEEEEEEEDCDDDDDDDDDDDDDDDDD
@74L
CTGAGCCAAACATCCCCTTCCCACCACAAGGCTTTAAGCAGGAGTACCACGACCCAGTGTATGAACACAACACCATGGTTGGCAGTGCGGCCAGCCAAAGC
+
B@CFFFFFHHHHHJJJJJJJJJJJIJIJJJIJJJIJIJJJJJJJGHIJJJJJJJJJHHHHHHHFFFEFFDDDDDDDDDCDDDDDDCCDDDDDDDDDDDDDD
@74M
CACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGC
+
@@@DDDFFDHAHHIIIEHIIIIIIIGIIGIIIHGGHG>DDHEEHHGGGHIIIHIIIIIIIIIGGEA@DAHGDEFFFACECDDBCCCD>CD?CAC@CCCD@B
@74N
TGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGC
+
===<AA?ABABA;C>BC4?=<+@<7A@5=ABBBABBAA<ABABBAAAAAAAABBA;;>BABBAAAAA@@>;=3>36--;;>>?;?>9;>?9815998=;;
@74O
CACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCC
+
CCCFFFFFHHHHHIJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJIJJJJJJJJDHIJGHHHHHHFFFFFEEEEEDDDDDDDDDDDDDDDD
@74P
GGTGGCTGATAGGACTTCAGAGGCTCTGCCCCTTTGTTGGCAGGGAGGCTTCCAGCCTGAGAGCACTCCCAGTTTGGATGCTGGACTTGCAGAGCTGGCTC
+
<;?DD>DA:ABBCB3;E,CB<CEC38C+*1CE>D><?9BB<306:(0-(8).88@@;@67=7=(.?A@D@@;.;;35-((93(:55:A>5((4(3:93+9>
@74Q
AGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGG
+
@?@DFFFFGGDDD<FBBFGGEGGDHIHGIIIIIFEGIIGIDGHGGGDDGDHGHFE4BBFFHBGICHDDCEEEH?BCDECECCECCCCA?CC=BB@@@CCB
@74R
CGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHHHFFFFDCEEEEEDDDDDDDDDDD?CCDDDDDDDD
@74S
CAAGCATAAAGATGTCATCATCAACCAAGAAGGAGAATATATTAAAATGTTTATGCGCGGTCGGCCAATTACCATGTTCATTCCTTCCGATGTTGACAACT
+
?@@;DDDDHFBDAHH?GGIIIIHH3AEGBG>GHCG=FHEGFAD?DGG@?9??FC?@DG<G;BHBBB<A@@CCCCCC;AAC@;AACCCC@BBB?@CC>CCBC
@74T
CCATGTTCAGCGTAGAGTCGCTGGAGCGGGCGGAGCTGTGCGAGAGCCTCCTCACTTGGATCCAGACATTTAATGTGGATGCACCATGCCAGACCGTGGA
+
CCCFFFFFHHHHHHJJJJJJJJJJIJJJJJJJHFDDDDCDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDEEEDDCDDDDDDDDDDDDDDCDBDDD<ABB
@74U
GTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTAC
+
@@@DDADDFBDBBDBFFHCEEEH<:ABFHCAF<FHIC@DH<FH@HGGB@GEF7@DHGGIIE@AEHHFHD;@DC>@>>>A@;;:1??(9??98C<8>@:AA@
@74V
CAGGAATCGAATGAAAACACTTGGTAGACGGGACTCGAGTGATGATTGGGAGATTCCTGATGGGCAGATTACAGTGGGACAAAGAATTGGATCTGGATCAT
+
1???ADBDFH?FHHHGEBFFDHEHEFEHHB@FC?D?BBD*?BGH?BBDACD@5FGC==E;7DHHHCB?BDEDCC;@CB?@BBC?>9>ACCCCCC@ACCC?@
@74W
CTTAAGAACACCATGGAGACCATAGACTGGAAGGTCTTTGAGAGCTGGATGCACCATTGGCTCCTGTTTGAAATGAGCAGGCACTCCTTGGAGCAAAAGCC
+
CCCFFFFFHHHGHJJJJJJJJJJJJJJJJJJJIJIJJJJIJJJJJJJJJIJJJJJIJJJJIEHIJIHIHHHHGFFFFFFFDDDDDDDDDDDDDDDDDDDDD
@74X
ATTTAATCATCCCAACATTCTGAAGCAGCTTGGAGTTTGTCTGCTGAATGAACCCCAATACATTATCCTGGAACTGATGGAGGGAGGAGACCTTCTTACTT
+
@C@BDFFFHHHHHJJJJIJIJJEIJIJJJJJIJFHCFHIHGGIJGJHIJJJJJJJJJJJJIJJJJJJJJJIEHHHHFFFE@BDD@DD@BBDDDDCDDDDDD
@74Y
AGCAGCTACCCCATGGACCACAGATTTCGCCGCCAGCTTTCTGAACCCTGTAACTCCTTTCCTCCTTTGCCGACGATGCCAAGGGAAGGACGTCCTATGT
+
@@@DFEFFHHFGHGIIJJJEGID>HIGHCHGGIEGGI9FFE@GIGIIIJJJGJJBHHGHHGB@EEDF@ACE<:@BBDDDDCCDDBDDDBBDB>BDBCCDD
@74Z
CACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATG
+
CCCFFFDDHHHFHIIGIGHIJJJJJJJCGGHHGGIFHIJIJIGIIGHJJIIIGIHCHHEIIJJGGHIGIHFFEHFF>CBD>@EEC?BDDCCCDDCDDDDDD
@750
TTTTAATCTTCTAGAAAGGAATGTTTTTGATTTTCGTTCTCCAATTTAGTCCATTTTATTGCTAAAATACAAAAGTTCACGTATGAAGTTCTTGCATTCGT
+
CCCFFFFFHHHHHJJJJJJJJJJIJJJJJJJJJJJIJJJJJJJJJJJJJHHIJJJJJJJJJJJJJJJDHIJJJJJGIHHGHHFFEFFFEEEEEDEDEEDED
@751
CTTCAGGAGCCATGTGGGGAGATGACAGAGGTACCCCCATGGCTCAGAGTTATGATCAGAATCCTTCCCCTAGAGCAGCTGGGGAGAGGGACGATGTCTGT
+
CCCFFFDDHHHFHJFHIGIIJGGIJJIIIGIBFHIJJJIHIGGAHIJGICGGIJGGIJIJHHHHHHFFFFFDEEEEDDDDDDDD?B?BDDDBDDDD?CDCA
@752
CAAATAGAGGAGGTCATAGAGAGCTTCCAAGTTGAGAAGTGTGTAACTGAGTATCAGGAAGGCTGCCAGGGACTGGGCCCCAGGGGCAACATTTCCCTGGG
+
?;?D<D;+=:22@EDDEB@E+3++2<22*1*1::*CBDB1B?00?BD<?B<B88DC?B)(=;C=C@A77@'-5=?9?9(9';;>8/;???1+(44:(44<>
@753
GCCTGAAGAGGTGGCCCGACGTTGGGGCATTCAGAAAAACAGGCCAGCTATGAACTATGATAAACTTAGCCGTTCACTCCGCTATTACTATGAGAAAGGA
+
?@@FDFFF?HHCDFAHGEEGGDEHIDGHIGEFIJIIIIIHIGGGAHGEHAHECEFEEFFEEEE>@CCACCDDDDCCACCC?BD<BDD@C@DDCDCDDDDD
@754
CGTGGATAATGTGCACCATAACCCTCCCACCATTGAACTGTTGCACCGCTCCAGGTCACCTATCACGACAAATCACCGGCCTTCTCCTGACCCCGAGCAGC
+
@@?DDFFFHGFFHGGGBEIHICHICGGIJIIIJJGHHGHIIJIIJJIIJJJJIJIIJIJIIIJJHHHHFFCCAEDDDBDDDDDD>CCDACDDDDDBDDDDD
@755
AAAGAATCTCCTGTCTCTGCTGGAAATGATGCCTATGTTGACCTTGATCGTCAGCTGAAGAAAACTACAGAGGAACTAAATGAAGCTTTGTCAGCAAAGG
+
@@@FDDDDAH?FFC:FGII@EGIGFHCHEDHCGEFCCEFGGGGGIGCF@GBFB@??@A<B<CGIIECFEGCGHCAHEEHDFFED?@@@CCECD@CCAC?C
@756
GATGACCCCCAATTGAAAAGAGAAATAAGGTTAATGAAAAACAGAGAAGCTGCTCGAGAATGTCGCAGAAAGAAGAAAGAATATGTGAAATGCCTGGAAA
+
@@@DFFFFHHHHHJIJJIJGDHGIJIIIJJFHIFIIJJJIJJJIIGIIJIIIJIGIIIIJFIDEHCDEFEEEEEDDDCDDDCCDEBDDEDCDDDDDDDDD
@757
GTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAG
+
CCCFFFFFHHHGHFIIJJIHIIJJJIJIJJJJJJJIJJJJ?FHIJJIIJGIIJJIIJJJIJIGGFHHHHFFCDB<ABCDCDDEEDEDDDDDB
@758
CCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGT
+
@@@DDDDDDA:<CHB3<<::AEFHED;@?FHDG?DG0BFH<BDGHFGFABDCFF@GGGA@G@=DHHFEECA;@(;@DCDD@CBA8==<@<@BBBB<B@B:
@759
CTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTT
+
CCCFFFFFHHHHHJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJIHHHHHHFFFFFFDDDDDDDDDDDDDDDCDDDDDDDD9@BD
@75A
GCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGC
+
CCCFFFFFHGHHHJGJJJJJJJJJJJJJJJJJJJIJJJJJJJJJIJJJJJJJJJJJJJIIIHIJHHHHHHFFFFFDDEEDDDDDDDDDDDDDDDDDDDDD
@75B
GGGTCACCACCAGCTATTGGACCTTACTATGAAAACCATGGATACCAACCGGAAAACCCCTATCCCGCACAGCCCACTGTGGTCCCCACTGTCTACGAGGT
+
?<@DBDDDFDFHFIAEEEHF@GE@EHIHCHIIIIGIGHEHIIGHHFDHHIGFEGHCHDEE?AA@BCBCCB;,;<<9?<@>>CCCCB<CB<C:CCCC<<>>)
@75C
AGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTTATGGGCAGG
+
CCCFFFFFHHHHHJIJJJJJJJJJJJJJJJIJJJJJJIJJJIJJJJJJJJJIJHHJJJJJIJHGFFFEDDDDDDDDDCDDCDEDDD9<<BDDDDDDDDDD
@75D
GTCGAGGCATGGAATTTAAACTGATTGAGCCTGAAGAGGTGGCCCGACGTTGGGGCATTCAGAAAAACAGGCCAGCTATGAACTATGATAAACTTAGCCGT
+
@@CFDFFFHHHHHJIJJJJJIJJIJJIJJJJJJIIJIJJDHIGJJIGIIGIHHHFFDEECEEDDDDDBDDDDDDDDDDDDDEDDCDDDEEDDCDDDDDDDD
@75E
CCAGCTCCCTGGACCACCCGGATGAGCGGGCCCTCACCATGGGCGACCTCATCTCATTTGCCTGGCAGATCTCACAGGGGATGCAGTATCTGGCCGAGATG
+
@@<DDEDDBDBH?EFGEHEII>HIIIIGIG6AFCEHEAH>EAEEF<93>CCCCC>>@A>DCC>CB89?8>CDAACCCBCCCCBBCCCCC>CDC@<>BBCB>
@75F
CTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTT
+
@CCFFFDDDHDFAHEB;<IEHHIHEEEGHIGEFDHCCGHGEGIIGIGGCE9DFIIBGEGECD>76@;=A>EDFFFCCCCEEC>CCC:AACBBCBBCCCCCD
@75G
AAAGCAATATGATCTTCAGTTAGTTCGTTTTGAACCTTGGGCTGAATATCTCAATCTTAGCTACAAGGCTAGAGTTATATAATACAAGAAAAGTAAAATG
+
((-2()):).)2))).@))3))))))2()222(.2()).:(()07)09)).))009).)3)).71))(()).)).))))))))))))).((.(--(-(-(
@75H
TATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGG
+
??@D:BD?3+<:AA?;@<FF8AE@@CC;BF??:BDGFG9<<??AFFECCEFFFD@BDBBCB@A;@ABB(-59<??@?2<<<::+4@BBBBB<?BB?A>A>>
@75I
GATTGTTTCTGCATCTGAATCCAGAAAGGAACTAGAATTAAAACATGAAGCAGAAGTTACAAATTACAAGATAAAACTTGAAATGTTAGAAAAAGAAA
+
CC@FFDEFHHGHHJJJJIHIGIGJGIJJIIIIIIJJJJJJJJJIJJIJIJIIIIIIGIJJJJIJJIIJJJJIJJJI@GFEHHHHFFFEDFFEDEDDDD
@75J
GGATTTTTCAAAAGCAGATTCAGGTGTTCATTTATGTGTTATTGATGACTCCAATGAGCATATGCTTACTGTATG
+
?@?BD?DA:DBFBFEGFFE@I?C@3:AFE@FH@CFB1@:B?GGA?:9:::BFBDD@G<B<?@FFCBBFBFG87)8
@75K
AACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCC
+
CCCFFFFFHFHHFHJJJIJIIGJIJJIGHHIIIJIJIJJJJJJIJJJIIBFGIJJJIHIJJJIJJJHHFFHFFFEEEEEEEECDDDCBDCDDDDDDDDDDD
@75L
CTCTGCCACAAACTGTGGTGATGACATCTCCTGTGACTCTCACCTCTCAGACAACTAAGACAGATGACCCCCAATTGAAAAGAGAAATAAGGTTAATGAA
+
;?;DDDDDDDB?DEB<C;+A3<?AFBFDFFDEC??EBDDDEIEAD;:?B?DEDIDDDE>8@B@@EEC@CCDDD=@DAA;A>A=A?>AAAAAA>>>>AA>>
@75M
GAAGAAGTTAAATCTTTAAAGCAAGAGAAAGAACAAGTTTCATTGAGATGTAGAGAGCTAGAAATCATTATTAACCACAACAGGGCAGAAAATGTACAGTC
+
@@CFFFFB?FFFFEIGIJGGIEGGGIIJIGHJFIJII?DHABFHICHGHFFAGBGBFECCHIIIECEGIIGGIJJIIJHHHC?BEDBDDCAACA5>@DDCD
@75N
GAAAAGGAAACCTCAAGCTGAGAAAGTTGATGTGATTGCCGGCTCCTCCAAGATGAAGGGCTTCTCGTCCTCAGAGTCGGAGAGCTCCAGTGAGTCCAGCT
+
CCCFFFFFHHHHHJJJJJJJHJJJJJIIJJJJGHIJJJJJJIIIJJJJJJJJIIIJJJJIJJHHHHFFFFDEEEDDCCDDDB=@BDDDDDDDDDDDDDDDD
@75O
CTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJHIJJJJJJJHIIJJJJJHJJJJJJJJJJJHHHFFFFEEDDEDDDDDEEDDDDDDDDDDDDDDDDDDDD
@75P
GCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTTATGGGCAGG
+
@@@FDDDFAFFFHIGIFHHJGIHIIIJIJFGGIIIFHGIIJJII>DGGCEDGHIDGHGIEHAEHDDEB?BCDDDDBCCDCCCABD3<<BCCCDDDD?BB
@75Q
GGAATATTCACTTCTAAAACAGACACATGGTCCTTTGGAGTGCTGCTATGGGAAATCTTTTCTCTTGGATATATGCCATACCCCAGC
+
CCCFFFFFFHDHFHIIIGHBHIIIDGIIIIIIIIIIGGECFHCHIGAGGGEHIGIHDGEHIIIAHGGAFDHGIIIIIIGHHHHFFFF
@75R
CCTGAAGCCGTCCACACTGCGTGAGCTGGAGCGCTATGTCACCTCCTGTTTGCGGAAGAAAAGGAAACCTCAAGCTGAGAAAGTTGATGTGATTGCCGGCT
+
@@@FFFDDFDHFFFHGHEFHI@GGHIIIGICHIIGHDGFGGIHIGIDHGHGIIGB<>BECECCBBCCC?DDCDD>AC@BDACDDCCDCDC:>@CC>A3993
@75S
CTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGT
+
@C<DFFFFHBHHHIJIIJEEGGEIIF?GIIJIEECGIJIJJGGHIIGGIGHGEIJJGIDGIGHIEGIHFHEHHFDFECEDDBBDDDDDDDDDDC@BCDDDA
@75T
CTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTC
+
1:?DD>B:DD:AF>F?FAF:CDC?CDC??D;)/?;(8=B;87@F9F8@D;7)=9?E>?;@7?;;;6;A@9?;@A;;(:@B,,3?A>?@@?9<3>:(2284(
@75U
CACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGAT
+
@@@DBD?DDFDDFI3C?@F:@BF4?CEGGCFEGI>809B@<D@DDDDFIEFIACA9CFC@@EFCA>BDDD@B@BC???@AAA;;@BAA1;99BB?B>AB>>
@75V
CTCATACACCGAAACCTGACCGGGCCTTCCCAGCTCACCTCCCTCCATCGCAGTCCATACCAGATAGCAGCTACCCCATGGACCACAGATTTCGCCGCC
+
;??DDDDDDD8)@@8?CE;ACC1CDDD?BDD<DD?D<=B=A@CICDICEA(;=D@A@;A@A@>=>>>>5>?AAA????939:49<88<(4>A3+09;99
@75W
CCAGAAGTCATCAGAATGCAAGATAAAAATCCATACAGCTTTCAGTCAGATGTATATGCATTTGGAATTGTTCTGTATGAATTGATGACTGGAAAGTTACC
+
++:?:ADA4?B::CEE9?:A?EA+AA<AE322C4?;3C:9C?4C<?::B**909?9*9*?488BDCAB:<.8.8@7=)74=>)7))=7))=?@).6636((
@75X
GAGAAGCGGCAGCTCAGCTTGGACATCAACAAGCTCCCCGGCGAGAAGCTGGGCCGCGTGGTGCACATCATCCAGTCACGGGAGCCCTCCCTGAAGAATTC
+
@@@;DD?DAAFFDHHIGHGGEGGCFHGGGCH8BDBFCGEBH6B<BAAA;;;=?BB@6:7<B<@>@AC@CCACAC@CCCCBBB@BBBBCA8?<3<C@ACCCC
@75Y
CAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGG
+
BCCFDFFFHHHHHJJJJJJJIIIJJJJIIJJJIJJJJJJIJJJJGIJJJJJJJJJJJJJJJJHHHGFFFFFCEEDEDEEDDDDDBDBCCDDDDDDDCDDDD
@75Z
CCATGGACCACAGATTTCGCCGCCAGCTTTCTGAACCCTGTAACTCCTTTCCTCCTTTGCCGACGATGCCAAGGGAAGGACGTCCTATGTACCAACGCC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJIJJJJJIJJJJJJJJJHHHFFDDDDDDDDDDDDDDDDDDDDDDDDDCDDDDCDDDD
@760
CCCGCTCATTGCCAAAAATTCACCGCAGTGCATCAGAACCCTCCTTGAATCGGGCTGGTTTCCAAACAGAGGATTTTAGTCTATATGCTTGTGCTTCTCC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJIJHHHBEFFFFEEDEEDDDBDDDDDD@CEDEFEEDEECDDDDDDDDD
@761
CGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCA
+
CCCFFDFFFHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJIIJIHHHHHFDDDDDDDDDDDDDD@CDEDDDDDDDDDDDDDDDDDDDD
@762
CCTACGTGAAGAGGAGCCAGGGTCGGATTCCAGTTAAATGGATGGCAATTGAATCCCTTTTTGATCATATCTACACCACGCAAAGTGATGTATGGTCTTTT
+
@C@FFFEFGHHGHJIIJIJIJIDGHIHJJJGIJJJIJIIIJGJJJIJJIIGIIJJJIJJJHHGHFFFFFFDFFECEEBDDBDDDD>AADDBDDDDDDDDDD
@763
GTTCTTACTGGAGACTCAGGTGGAGTCATGCTTATATGGAGCAAGACTACTGTAGAGCCCACACCTGGGAAAGGACCTAAAGGTGGATATCAAAACAGCA
+
=:7A1+2<A88@37<+?A@@CBA3A+??B?4:?*?@<A4*1)0:)0=<<=??9**9=*=AB<AAA)=A((.6>5;(;>((.;>(-(,-55(5:;(599(5
@764
GGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTAC
+
CCCFFFFFHHHHGJJJJGIIJJJJIJIJJJJJJJJJJJJJIHGGIIJJJIJJIIJHHGHHFFFFDD=@CDDDCDCCD@CCDDDDDDDEDDCDDBDDCDDDD
@765
AGCGGCAATTCACTAACAAGAAAACAGGGAATTTTTGGGAAATATGAAAAGCCAAAATTTGTGCAGTGTTTAGCATTCTTGGGGAATGGAGATGTTCTTAC
+
@@@FFFFFFGHGGJJJJJFIIIIIGGIJGGGGIJJJJIIHEGCAEFGHIJIJJGJIIIGHHHGHHFFDFFFECEECDDDEDDDDDDDCCCDDDCEDEEDDD
@766
GTCAGAAAGCAACTGATAGACGTAATCCCAAAGCAGTCTACAGTCTGCTATTCTCCCAATGGGCATGGCGTGCTCTTCAGGCGGGGAGACAGAGACCATG
+
CCCFFFFFHHHHHJJJJJIJJJIIIJJJJJJJJJJJJJJJJJJHIJJJJJJJIJIJJJJJJJJIEHIJIHHFFFFFFEEEEDDDDD<>98?<??CCBCCD
@767
CTTCATGAAGACCTCACAGTAAAAATAGGTGATTTTGGTCTAGCTACAGAGAAATCTCGATGGAGTGGGTCCCATCAGTTTGAACAGTTGTCTGGATCCAT
+
@@@DDDFDFDFBDGBDGEGEGGEGGDGGE+A?DDECIF?DCEHFCEFCECEEGGEBDCFE@EE>F=CGG;CEHEEABC@@>B>A;;>@@A@A@CC@@>AC>
@768
CCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCT
+
??;+=D>DDDD:D??DB@BE:<3+C?BCAEAB):)???3*???*?B*0*0?B3**8=;A/A556?>76>:@=2;=5=2(5>3598;>;AA9<9>>A<(3>:
@769
GACCGGGCCTTCCCAGCTCACCTCCCTCCATCGCAGTCCATACCAGATAGCAGCTACCCCATGGACCACAGATTTCGCCGCCAGCTTTCTGAACCCTGTA
+
CCCFFFFFHHGHHJJJJJIIJIIGIJJJIIJJIIJJGIIJJJIIJJJJJJIIJGIHHHHHFFFFEDCDDDDDDDDDDDDDDDDDDDDDDDDECDDDDDDC
@76A
AATTACCATGTTCATTCCTTCCGATGTTGACAACTATGATGACATCAAAACGGAACTGCCTCCTGAGAAGCTCAAACTGGAGTGGGCATATGGTTATCG
+
@@@FDDFFHHHGHIIGHHIJIJGIEHFHGIGHGJIIJJIIJIIGGHIJGEHIJIIGIIIIIJJIGIIJJJHHE>H>@DDFCC;@CDDDDDDDDACCDDD
@76B
GGATTGTCTGGAGCGCCTGACCGTGGGATCCACGCACCTCGGGCTGCCATAGTGCTGGGAGTACAAGTCCGGACCGTGATGAGTGGAAAATGCGCGACGTG
+
1+1?12<222+22+27<)2++2))1)1)*0)*0)).(-82=A''-4(67).77>;7>>5.((--(((((,(''&&)&+0(++3+(235(((((&&00&)&2
@76C
AGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTG
+
@@@DDDFDHHHHHIIGIJJJIIJGIJJJDDFHGEHIGGGGIIHIIJIEGBHIEEHHIJJGIIEIHCEEFGFGDBDB@@ABDDDDCDBCDDCDDDDDDBBBD
@76D
GCAGGGAACTACTCCCACCCTGGAGCCTCCATAGACCTAACCATCTTCTCCTTACACCTAAAAGGGGTCTCCCCTATCTTAGGGGCCATCAATTTCATCAC
+
;==?A0?AA+>=<C+2?+AA??++51?=?B3*?**?=AAAAB3*9**909==4=>AB3AA7)77;(',').;(3(,(5-(5(-(3''8,;;388(33+4((
@76E
ATGCGGTAAATCTCATATTTTCTTCTGGACCTGGAGCGGCAATTCACTAACAAGAAAACAGGGAATTTTTGGGAAATATGAAAAGCCAAAATTTGTGCAGT
+
@<;DDDDAFHBDHCIDEHIIIIIIIGII>BFGIG@GEGIIIEIGGHG@CCFGIEHIIE>EACBBE@@CAEDDDDDD@AD@DECCC?BC?C?@CCC>ACCCC
@76F
CAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGA
+
CCCFFFFFHHHHHJJJJIJJJJJJJJJJJJIIIJJJJJJJJJJJJJIJJJJJJJJJJJHHF;BDDDDDDDDDDDDDDDDDDDCDDDDDDDDDD
@76G
CTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTAT
+
CCCFFFFFHHHHHJJJJJIJJJJJIJJJJJJJJJJJJJJJJHHJJIJJJJJHEHHHHFFFFFFEEEEDDDDDCDDDDDEDCDDDDDDDDDDDDDDDDDDDD
@76H
CCCACGTCAGAGTGTGGGATTCTGTTACTCTATCCACACTGCAGATTATTGGACTTGGCACTTTTGAGCGTGGAGTAGGATGCCTGGATTTTTCAAAAGC
+
@CCDDFDDHHDHDF?FGEGIGIIIIIIIIIIIIIIIIIIIIIIIIIIIGGGIIEIIIIGIIIIIIIFIGE=BD?B>AECCDDDDDCDBCDDDDCCDDDDD
@76I
GTCCATTTTATTGCTAAAATACAAAAGTTCATGTATGAAGTTCTTGCATTCGTTTTTTTTTGGAGCAGGCATATGGGCAACAAAGCTATGGAACCTATGG
+
@@@DFFFFHDFFFIJGGEFCIGIJJGGHIGIEGH>HICGFGHHECGA<FIDHFCEDHHGEH6/77@DECBA>>;CA@DD<5?B?:5@>>A@:>C@?CD::
@76J
CTGTGCGAGAGCCTCCTCACTTGGATCCAGACATTTAATGTGGATGCACCATGCCAGACCGTGGAAGATTTAACGAATGGGGTTGTGATGGCCCAGGTTCT
+
@CCFFFFFHGHHHJIJJJJJJJIJJJJJJIJJIJJJJJJJFIIJIIJJJIJJJIJJJGJJJEHHHFFFFFEEEDDBDDDDDDDDDBDDEDCCDDDDDCDDD
@76K
AGGAGTACCAGGGCGTCATTGCCTGGCAGGGGGACTACGGGGAATTCGTCATCAAAGACCCTGATGAGGTGGCCCGGCTGTGGGGCGTTCGCAAGTGCA
+
@CCFFDFFHGHHHJJIJJJIJJJJJJJJJJJJJGIJJJJJJHFFFFFDEDDDDDDDDDDDDDDDDDEDD?BDDDDDDDDD8ACDD@B@BBBDDDDCCDD
@76L
CCAAAGCTTTCCCCCTCCTCTGATGATTAAACAGGAACCCAGAGATTTTGCATATGACTCAGAAGTGCCTAGCTGCCACTCCATTTATATGAGGCAAGA
+
@C@DFDBDHFHHFHIBFHEGCFHHHHIIGI@EH>BHIHIIIIBHFGEIIHIIIGHGGGEGDCHIGEAGECHHEEHFF@DFEACEEDEBCCDCDDDB?BD
@76M
CCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCC
+
@@CDDED>BFFFHIHEAFGHIGBHGGGIIIIAFGDDCHGGHFG?DDHIIIIGGCHGIIGGIGBHHBF@BB@CCCDDDDDCDEDDDCDDDDDBDBDDDDCDD
@76N
CATCAAACAAGAGCCAGGAATGTATCGGGAAGGACCCACATACCAACGGCGAGGATCACTTCAGCTCTGGCAGTTTTTGGTAGCTCTTCTGGATGACCCTT
+
CCCFFFFFHHHHGIJJGGIIGIHIIIIJGIJJJGGHEHIIIJIJIGJJJJHFDDDCABCCADDDDDDDDCCCD?CDDB@D8ACDCCCDCCDCCDCDCDBCC
@76O
AAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCAC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJHHHFFFFDEEEEEEEDDDDDDDDDDDDDDDDDDDDDDDDDEDDDDDDDD
@76P
CGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCG
+
CCCFFFFFHHHHHJJJJGHIDGHDHIIIJGIIJJJIIIJJJJJJJHHHFFFFCEEEEEEDDDEDDDDDCDDDDDDDCDDCDDDDDDDDDDCCCEDDDDDDD
@76Q
GTGAAACTCTGAGAAACAGCACTCATAGTAGCACAGCTGCAGACTTACTACAAGCCAAACAACAGATCCTCACTCATCAACAGCAGCTTGAAGAACAAG
+
@@@FFFFFHHHFHGIJJJJJJJJIJJIJGJIIIJJJJIJJJIJJJJJJJIIJJGIJJIJJIJIIJIJIIIJFHHFFHDFFDFECCEEDDDDDDDDDDDD
@76R
AAACAGGAACCCAGAGATTTTGCATATGACTCAGAAGTGCCTAGCTGCCACTCCATTTATATGAGGCAAGAAGGCTTCCTGGCTCATCCCAGCAGAAC
+
@<@FDFFDHFFGHGIIJGHGHEGIEIIIIEHGEHIEFDHE@DCGGCGDGEGBFAF?=FEHGHHJGHIIIDGGHFDHB>C?DF@CEEED@BCCBCBCDD
@76S
ATCACAGTGTAATGAAATGTACATAAATAGTTCTCAGAGAGTAGAATCAACTGTGATTCCTGAATCTACAATAATGAGAACTCTACATAGTGGAGAAATA
+
@?@DDDD2A=ADDA4AFEHCFEECFBBH@FHHIIE>BE?:?FDDBG<:DGIFA::??9BDGEBD8?BB8BFGIEF>F;@=C=777C@>EAEC9BB>BB>@
@76T
GGATAACATTCATGATACTGTGATTATTTGTCTTGTTTTGTTGTTTTTGTTTTGTTTTTTTAATCTTCTAGAAAGGAATGTTTTTGATTTTCGTTCTCCA
+
CCCFFFFFHHHHHJJJJJJJHHIJJJJJJJHGIJJHIJJJJJJIJJJJJJJJJJIJJJJJJJJHHHHGHHFFFFFEEEEEEEEDDD@DDEDDDDDDDDDD
@76U
TTTTGCATATGACTCAGAAGTGCCTAGCTGCCACTCCATTTATATGAGGCAAGAAGGCTTCCTGGCTCATCCCAGCAGAACAGAAGGCTGTATGTTTGAA
+
88=1=:AABDD><4:E9@<+,3<<<BCFF4CE<E>DDEDFFACC><<?D)?DCB?;9B?C3.=).2=;@7AEI=?>9;;@;AD;;;@?A?,;>A>>A((5
@76V
GATTCAGAGAGCTAGACAGACAATAGCTGAACAAGAAAGTAAACTTAATGAAGCACATAAGTCCCTTAGTACAGTGGAAGATTTGAAAGCTGAGATTGTTT
+
+1==A@;,2?;CCC+3?CAAAC;BABA=ACBB@@7?=:*:??B>B<A>AAB70=>>AA>>ABB)8=AB>8>BBBBB>AA:5>>?>;>@>>;6>6=?;>?;;
@76W
GGACACAGTGCCTCTTTCTCACTTTGATGAGAGCATGGCCTACATGCCGGAAGGGGGCTGCTGCAACCCCCACCCCTACAACGAAGGCTACGTGTATTAAC
+
CCCFFFFFHGHHHJJJJJJJJJJJJJJJJIIJJJJJJJJJJJJJJJJJJJJJJJJJJFFFDEEEEEDDDDDDDDDDDDDDDDDBDDDDDCDB<C>CCDDED
@76X
CCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGAT
+
CCCFFFFFHHHHHJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJIJJJIJJJJJJJHHHFFFFFDEEEDDDDDDDDDDDDDDDDDDDD
@76Y
CAGCTACGGGCAGCAGACTGCATCAGGAGATATGCAAACATATCAGATCCGAACTACACCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATGACATCTC
+
@??B?DD@@1CCD<E?GFF@D3??FGCG;3?9DFD@BGDE@FBBDBDFEBA=556@)=CFEFFFFFDDBDDBC@>@BCB(5???BB:>?B@>::A:A>@4:
@76Z
AACAAGCCCACTGAGACTAATAAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACC
+
C@CFFDDFHGHBFIIJCGHGHJHEHJGIIEIGIIIJIJJIGJJI;@DGIGIJICCEHFFFFEECEDDDDDDDDDDDDCCDCDDDCDEDDEDDDDCDD:@CC
@770
CTCATTCAGGTGATGTGCTCTATGAACTCCTTCAGCATATTCTGAAGCAGAGGAAACCTCGGATTCTTTTTTCACCATTCTTCCACCCTGGAAATTCTAT
+
@;@;BDDDFA=?FHHEF>HHIDFGHGGGGAGGDEHAGCA><FAFGII@HFHGG>GI@DDC?@7B@DEEGEGHEEHBEEDDDECCCCBBBCBBCC@CCCDA
@771
CCGCTATTACTATGAGAAAGGAATTATGCAAAAGGTGGCTGGAGAGAGATATGTCTACAAGTTTGTGTGTGATCCAGAAGCCCTTTTCTCCATGGCCTTTC
+
CCCFFFFFHHHHHJIIIJJJJIJJJJJIJJJJJJJFHIJJJJIJIIGIIIIJJJJIJJJJJJJIIEGHGHHGGHHFFFFFEEDEEDDDDDDDDDDDDDDDD
@772
CCACCAGCTTGTGGAACCCAACGTACGGCTCCTGGTTTACAGAGAAACCCACCAAAAAGAATAATCCTATAGCAAAGAAGGAGCCACACGACAGGGGTAAC
+
@??DDFDDFFGHFGGBBGBEA;FFF@1?FGGI?D909B3?4?D@=B=BCAAEHGAE?9/?B7?>C:6>A>@5>ACDCDD:?B?A@C9?<>B&59?BBBBCD
@773
AGCAAAAGGAGCAGAAATAAAGACAACAAATGAAGTTGTTTTGGCTGTGGAGTTTCACCCAACAGATGCAAATACCATAATTACATGCGGTAAATCTCAT
+
?@?DDDFDDBFFHJIIIGIIIGJJIIGIJFGFBGC?FEDHHGIGGGGBFAGHCCGGCHCCHICHGHEHFHHF?CBCECCEECEACA;@?BB?BAC@@CCD
@774
TGATGACATCAGAACGGAACTGCCTCCTGAGAAGCTCAAACTGGAGTGGGCATATGGTTATCGAGGAAAGGACTGTAGAGCTAATGTTTACCTTCTTCCG
+
@C<DFFFDHHHHHJJJJJJJJJJJJJJJIIJJIIIIJJJJIJJJGJBFHICHGIJJJFHGJJJIIHHHFFFFFDC>CECCDDDDDDDEEDDDDDDDDDDD
@775
GGAGATATGCAAACATATCAGATCCGAACTACACCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATGACATCTCCTGTGACTCTCACCTCTCAGACAAC
+
@C@DBDDFDHHHHGHHEBHIIHIIIFDHIFIJGGIJIJJIJJJIIJGGEEHJJGDHIJIJIFED=CCHEGHHGEEHHFEBD@@CECEEEBCDCCDDDDDDD
@776
CTGGAGACTCAGGTGGAGTCATGCTTATATGGAGCAAAACTACTGTAGAGCCCACACCTGGGAAAGGACCTAAAGGTGTATATCAAATCAGCAAACAAATC
+
CCCFFFFFHHHHHFHIJJGHHJJJJJJJJJJJIGIJJJJJJJJJJHIIJIHIIIGIJJJJJJGIJJJFHHHHFFFF;A>CDEEEEDDDDDCCDDDDDDDCC
@777
CTGCATCAGGAGATATGCAAACATATCAGATCCGAACTACACCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATGACATCTCCTGTGACTCTCACCTCT
+
=?@=DDEFFDHH<?CFHGHIGIIIGHG<FBHHGHIGI@FG<?DFFHFDHBDHEGIEDAH>CC@FGGIGI)=A=EEEEEDFDCACCCC@CCCCC>C>>ACBA
@778
CCAGTCATGAGCAGGGCTTCTCTGTGGAACTGGAAAGTGAAATTTCAACCACAGCAGATGACTGCAGTTCAGAGGTAAATGGTTGCAGTTTTGTGATG
+
BCCFDFFFDFHHGIIIJJIIJJHIABEHIGIJIJJIG:CGIIIIIIGIIIIIGIJJIGHGCGGGGGEHGIJJHHGEHFE@DFDEABCECCEDD?CCDD
@779
CTGTGGGCGGAAGTGGGTGGAGACTTATACAAAAAGTGAGAAAAAAATATAGTAGGAATGTTTAAATAAAGAGGGTGGAAGGAAGGAAAGGAGTGCAAGG
+
+112++)+)))0)*1*1)))))*(****)))))((-.)).).7;(,'((-((((-(-((((((,5(,,9>(+(+&((&(++2+31(2+3(+(+(((5(+(
@77A
CTGCCACTCCATTTATATGAGGCAAGAAGGCTTCCTGGCTCATCCCAGCAGAACAGAAGGCTGTATGTTTGAAAAGGGCCCCAGGCAGTTTTATGATGAC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJIJIJJJJJJJJJJJJIJJJJJJIJJJJJJIJJJJHIJJGJJGHHHHHFFFDD:;@;;58ACDC:5(5;>@@
@77B
GTTTCTTTTGAAAATATGACTGTTGGGGAAGAAAGTAAGCAAGAACAGTTGATTTTGGATCACTTACCATCTGTAACAAAGGAATCATCACTTAGAGCAAC
+
=1144,:BDDD><CDAEAD?B>ED4+))2:))*1:1??:BD9BB90*98?*B<*/8)78/=A)77)===)..=)77;;;@A6;6;365->5(;>>((5>??
@77C
CTCTATACACACACAGCCGGAGGTCATACTGCATCAGAACCATGAAGAAGATAACTGTGTCCAGAGGACCCCCAGGCCATCCGTGGATAATGTGCACCAT
+
@@@DDAD?FDDHHGIID@:1C:?CCGGHGBFHIIIIIGIHIIIIDG=FG;@FGHICE@@=AEHAEEBEECCABB7?<?B?ABBBBBB4@C::4:>CCCBC
@77D
AGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGAC
+
CC@FFFFFHHHHHJJJJJJJJJHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJIHHHHFFFFFEEDDEDDDEEDDDDDDDDDDDDDD
@77E
GAGCGGCAATTCACTAACAAGAAAACAGGGAATTTTTGGGAAATATGAAAAGCCAAAATTTGTGCAGTGTTTAGCATTCTTGGGGAATGGAGATGTTCTT
+
?@@DDDDDHAHF?<B@BDEHGGIGEDHGIEGCEHIGI@FGBGHIEHGGIE@AGGIIHEH@EE;BCED@CCDC@;>CDCCCDCCBBB?BCCC<33::AADC
@77F
AGCTAGAAGACCTTGGTGATTTAAGGCGGCAGGTTAAACTCTTAGAAGAGAAGAATACCATGTATATGCAGAATACTGTCAGTCTAGAGGAAGAGTTA
+
C@@DFDEDHBCABEGA<ACHHGGIIEEHIE@D@?FGFCHCEEH@@C@FCDHIAEHCHCB@D:7?@DEAAC>ACCCCC@DC:CCC>>@>AABBB2?>@C
@77G
CGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTT
+
CC@FFDFFHHHHHJIGJJJJIGHGHGEGGIGGGHIIHIIJJJJJJJJIJJJJJJJJJJJHHHGFFFFFEDDDEDDDCDDDDDDDD@BCDDBCDDDD:ACCD
@77H
AGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACC
+
@@@?1ABD<??@CEFD=8)@@EFFBDGEB9CGF9D*??8;B?3BFFFFFEB>A;=DD>>;A6>66>A@@AA/8=?B@BB7+<1?BBBBBBBB3:::4+>8@
@77I
CAGGAGTCTTACACAACTGGGACTCCCAAAGCAACATCTTCTCACCAGGGCCTTGGAAGCACTTTGCCTAGAAGGGGAACCAGGAATGCCATAGTTCCG
+
CCCFFFDFHHHHHJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHHHHFFFFDDDDDDDDDDDDDDDDCDDCDEDD
@77J
TGGAGCCTTTGGAGAAGTGTATGAAGGAACAGCAGTGGACATCTTAGGAGTTGGAAGTGGAGAAATCAAAGTAGCAGTGAAGACTTTGAAGAAGGGTTCC
+
@@@FDDFEFFH>FEBDD<<<FBBBHHGDGFEF@FBFHHGGEEAFBHGIGGIIIBGIIHHBFCEHIIGGHIAEGHHFCH>377;;@@C>@;>;>;;@;?<A
@77K
AATACCAAAAGTTACCAAAACTGCAGACAAGCATAAAGATGTCATCATCAACCAAGAAGGAGAATATATTAAAATGTTTATGCGCGGTCGGCCAATTACC
+
?@@DDFFFHFHFDIJIJJGGGGIJGEFHABFGIJJGGDHGGFGHIEGEHHIIDGIGGHGGECGIEHHIJJJIIHFHEEFHFFFFDDD??BDDDDDDCDCD
@77L
CAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATAT
+
@C@D?EDD=DHDHIIFGGHIIGGIC@FHIIGICFHHIIGIDHGHIGIGEBGDHIIGGGIGIIIIGGHHEDF9@CEEEEDCDABDBDAACC?CCCEDEED
@77M
GTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACT
+
CBCFFFFFHHHHHJJJJJJJJHHJJIJJJHJJJJJJJJJJJJJJJJJJHIJJJJJIJJJJJJJJJJJJHHHHFFFFEEEDEEDDEEDDDDDDDDDDDDDDD
@77N
AACGGCGGTGAGGATTACAACTGTACTTATAGATGGCGAAGATAAAGATGGAAGGCCTCTACAACCCCACGTCAGAGTGTGGGATTCTCTTACTCCATCC
+
1+12707=))11):*00*0?>>A=*0**0*/=*/=)8'''-:.).7>33);)..(((-,5;;5((,8;5/&22(&(3((+++&839:8((((4::((+8;
@77O
GTTGATTTTGGATCATTTACCATCTGTAACAAAGGAATCATCACTTAGAGCAACTCAACCAAGTGAAAATGATAAACTTCAGAAAGAACTCAATGTACTT
+
@@@DDDAADDF?8EEGBGGIIGGDC@HIHIGCCGCHCFHCCHGHHGCDDFGGDFGIIIIIIII=CHGGGAHIIIIBEHHEEAADEEEBCCCCCCC;@>CD
@77P
CGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTT
+
@?<DDDDFDHGDFIIGGIIHGHEIEGHEHIJJIIJJEEGGGJIIIHHGJEIEBFGBHHIGEEHFEDECCCD@BBBC?@AC@CC=825A>CBCC?C?>ACDD
@77Q
TGGCTCACTAACTAACGTGAAAGCCTTACAGAAATCTCCAGGACCTCAGCGAGAAAGGAAGTCATCTTCATCCTCAGAAGACAGGAATCGAATGAAAACAC
+
CCCFFFFFHHHHHJJJJHIIJJJGJJJJJJJJJJJIIJJJJJJJJJJJJJJJIJJJJJJJJIIHHHHHHHFFFFFFEEEEEEDDDDDDDDDDDDDDDDDDD
@77R
AAATAATAGAAGAAGAAAAGAAAACTCTTGAGCTAAAGGATAAATTAACAACTGCTGATAAATTACTAGGAGAATTACAAGAACAGATTGTGCAAAAGAAC
+
CCCFFFFFHHHHHJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJIJJJJJJJJJJHHHHHHFFFFEEDDCEEEDDDDDDD
@77S
CCTCAGTCCTCACCATGCCTCAGGAGGTCAGGGCAGCCAGAGAGCATCCCACCTGCTCCCTGCTGGAGCAAAAGGCCCCAGCAAACTTCCATATCCTGTTG
+
CCCFFFFFHHHHHJJJIJJJIJJJJJJCFHEIJIJIJJJJIJJJJIJJJJJJJIGIGIJJJFHHHHFFFFFEEEDDDDDDDCDDDDDDDDDEDDDEEDDDD
@77T
CACCTTCAGCTACTTGTCTGCCACAAAGTGTGGTGATGACATCTCCTGTGACTCTCACCTCTCAGACAACTAAGACAGATGACCCCCAATTGAAAAGAGA
+
;<<((6=@?=>??;<)99;>4@?1.83)2=.;>.@.98;=<<?9698>1=9=8))<>).<>8=9>9;?@;?;;>>.<9=)9=86068;<8<>>55,:;<;
@77U
TGTAGACCTGTGTGTAGATATTTCAAAAGGCTGTGTCTACTTGGATCGAATGCTTTTCATTCACAGGGATCTGGCAGCTAGAAATTGCCTTGTTTCCGTG
+
;==2<<?=<2<C<=+@>23,?C4<333??A=+=:=?=11::=:77*00)00***0999*=>A>ABBBA;=A>AAB35AA97>37>;>;>>>(;?>?==51
@77V
CTCTGAGAAACAGCACTCATAGTAGCACAGCTGCAGACTTACTACAAGCCAAACAACAGATCCTCACTCATCAACAGCAGCTTGAAGAACAAG
+
CCCFFFFFHGHHHJJJJJJIJJGJJJJJJJJJJIIIIIIIIJJJJJJJJJJJJIJIJJJJJJJJJIJJJJJHHHHHFFFFFEEEEECDDDDDD
@77W
GTCACATCAACGAGGAGGACACAGTGCCTCTTTCTCACTTTGATGAGAGCATGGCCTACATGCCGGAAGGGGGCTGCTGCAACCCCCACCCCTACAACGA
+
@@@DADDFDA;?D@@@EF@EFHCEBFBHEHIHD@DDDFHF3??FB@GIIAH=<BGEGIC@AHGHGB><<=A?B===BCC>CCA?@>B3<9<>BBBACCB<
@77X
CCTTGGAGGGGCACAAACGATCAGTAAGAATACAGAGCAACGGCCCCAGCCAGGTACCTGCCCAGGATATGTAATCTCTCCTTTGCTTCCTGCACAGTTGT
+
@CCFFDFFHHGHHJJJJJJJJIJJIIJJJJJJJJJIJIJJJJIJJJJHHHHFFF?CEEEEEDDDDDDDDDDFEFDEDD@CDDDDCDDDDDCCDDDDDDDDD
@77Y
CACAAGGCTTTAAGCAGGAGTACCACGACCCAGTGTATGAACACAACACCATGGTTGGCAGTGCGGCCAGCCAAAGCTTTCCCCCTCCTCTGATGATTAA
+
@@@DFFFDHFFFHIIJIFIICCHGGIHIGJJJIJIDCIEHI>FGFIEGIGIJGBFGGGEHECEFFDCDBBDDDDDD?>CDCDDC<B>?CDDCDD>CDCDD
@77Z
GACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTAC
+
@@@BBDDDHHHFHJGHHHGGGIIBHGFGHHIGGEHIIIIIFHIIIJGIGGJJFIIHFAEHFDDDBCD>>?=>C?:?:<CCDDD:CCDCCDCDDDCDCCDD
@780
GGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAAT
+
CCCFFFFFHHHHHJJIJJJIHIIJIJJJEHJJJIJJIJIJJJIJHIIIJJJJJJJJHIJIJJJJJHGHFFFFFEEEEEDDDDDDDDDDDCDDDDD@CDDD
@781
GTGGAATTCTCCTTAAAAAACAGCATGTTCTAGAAAAGCCATGCTTTGGAGGTGCTGTAGGCTTGCAGCCAATTTACTGGAGCAGGGATGACGTAGCCC
+
@@<7BDDDFHHHHIHIICEGI?GGGEFGEGEBFFGDHAGCEDGIIGIGGGE178=EEHIIEGIIIGHHGHHFBCFFCCCECCCAC@:8C@CDDDBABCC
@782
CTCAGCTTGGACATCAACAAGCTCCCCGGCGAGAAGCTGGGCCGCGTGGTGCACATCATCCAGTCACGGGAGCCCTCCCTGAAGAATTCCAACCCCGACG
+
@CCFDFFFHFFHHIIHGJIGIIIIJJIJIIGGHGJDGIIJJGCHFD?BB<?CDDDDCDDDDDDDDDDDDDBDBDBCDDDDDDCDDDDDCDDDDDDDDDDD
@783
CACGAAGAAGAGCTTTCCAAACTGAAGGAAGATTTAGAAATTGAACATCGAATAAATATTGAAAAACTTAAAGATAATTTAGGCATTCACTATAAACAGC
+
CCCFFFFFHHHHFGGIHHIJIIIJIEGIGHIHJIIJJIIJJJJEHIJIJJJJJJJJJIJJJIJJJJJIIIJJHHHHGHFFFFFFEEEEEEEDDDDEDDCD
@784
TTTATGACGACGGCCTCTCAGAGGAGGAGACACCGCTGGTGGACTGTAATAATGCCCCCCTCACTCGAGCCCTCCCTTCCACATGGATTGAAAACAAAC
+
;;(-:.=45=83(-2(=9919=3(36<<=>(<)<'''5/.<5>??>6)8198831=6(,'7'(,(,29830+58(28<8(86::6/(8:56:(828699
@785
TGAACACAACACCATGGTTGGCAGTGCGGCCAGCCAAAGCTTTCCCCCTCCTCTGATGATTAAACAGGAACCCAGAGATTTTGCATATGACTCAGAAGTGC
+
CC@FFFFFHHHHHJGIJIJJJJJGIIJIJJJJJJIJJIJJJJJJJJJJJJHHGHHFFFFFFFFDEDEDDDDDDDDDDDDDDDDDEEDDEEDDDDDDDDCCD
@786
AGGCCCTCCAACCCCCCCACACCATCCAGCACGCCAGTGTCCCCACTGCATCATGCATCTCCAAACTCAACTCATACACCGAAACCTGACCGGGCCTTCCC
+
CCCFFFFFHHHHHJJJJJJJJJJJIJJJJJJJFHIJJHIIHHHHHFFFFEEEEEEDDEDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDD
@787
GTCCAGGCACAGATGGAGTACAGGGACTTCAGACATTAACCATGACAAAATCAGGCAGTACTCAGCAAGGTACAACTATTCTTCAGTATGCACAGACCTCT
+
C@@FFFFFDFHHHGJJJJFHIDHIJGHIIEGGIIGIIJIJJ3DHGIGIIJJJIGIJIJBFHCHGGHIIIJ7?AEHHFCEFFFEEDE@@CDDDCDCCDDDDC
@788
CTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACC
+
CCCFFFDFHHFFHIJHHIIGIJJIJIJJJJIJJIJJJIJJJJJJJJJJIJJHHIJIJHH?DFFEDDEDDDCCDDDDDDDEEDDDDDDACDCDDDDDEDCDD
@789
CACCTTCTCCCCAGCCCTCTTCACAACCTCTCCAAATACACAGACAAACTCCAGAAAGCAAGAATGCTACTCCCACCAAAAGCATAAAACGACCATCACC
+
CCCFFDFDBFHHDGIJJGEHJICFCC=CGEGHIJGHGEF?FDH@DF>FH@B@F@FFDGEH9=DEHIFEFFGGFFFFDACDDDDDCC@>3@6?@B5>AA>?
@78A
ACCGGCAGTCTCGATGATAGTATTTCTGCTGCAAGTACTTCTGATGTTCAAGATCGCCTGTAAGCTCTTGAGTCACGAGTTCAGCAACAAGAAGATGAAAT
+
+:=+<?A02<+2AA>A@,<A2<++++*:**::**:1?=??==B4*=09900===AAA<A;>)8)/).).)7=).>=/;'((;>;3;>(;;5;=(,99=???
@78B
CTTTATCCTTACTCAGACTGCCCTCAATTCGACTGCCCCGGGCACTCCCTGTGGAGGCCTTGAGGGTCCTGCACCTCCATTTGTGACAGCATCTAATGTG
+
1+7?7?<22AC=@@B++237A@C7<3<?2<71:A==7A1:84AA;7>BABB.=;;6>A;;>>@@>;=@;?;5(59?==;==;:(,98;32(333::;8:8
@78C
CGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCA
+
@@@DDDD>BFBFF@AEGBECHCEGGHDHHHG8HH8GBFDHHHGGGIIHHIIIIIGEEHHGFDCDDBADDBDDDDDFACDDCCDDC<BBDBBBDDDDDDC
@78D
CACCTGTGTTGTCCCAGAAAAATTCGATGGAGACATCAAACAAGAGCCAGGAATGTATCGGGAAGGACCCACATACCAACGGCGAGGATCACTTCAGCTCT
+
@@?DDDD>FFBADHI<<<CGII@HGDEHIG;FHHCH>FBHBEHFH@FA?/?DHGG=FCHCAEBAEEEE?DCCACCCCCC??BBBBBB>93(3:>CCAC:4@
@78E
GGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCATCAGAGCAGCAGCTACGGGCAGCAGAGTTC
+
@@@DDDDFFHHFFGGHJIIDGIIJIGGIJJJJIECGHIJJGDGHFGGHIJIIEGGIGGJJJJJIHEHCHEFFFF@CCCCB?BDCDDBDB:69?BBCBCDD
@78F
CTCAGTGCTGGCAACATCAGCCTGAAGACAGGCCCAACTTTGCCATCATTTTGGAGAGGATTGAATACTGCACCCAGGACCCGGATGTAATCAACACCGCT
+
8==AD2=DFA3:DEAFF>?:A?FGIICHBGBB;??FDGIE@BB@@FB?BBFEF@FD;@FFAEA=@CECE>E>DB?D?CC=;=98''3,;BD>>43>+<0.5
@78G
AAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJHHIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHHFFFFFFFEFDDDDDDDDDDDDDDDDCDDDDEDDD3
@78H
CTGTTGCCAAGTCTGGGAAGCGAGCTCTAGCTGGAGGTCCAGCCCCTACTGAAAAGACACCCCACTCAGGAGCTCAACTTGGGGTCCCCAGGGAGAAACCC
+
=<?ABD;D??C:<<D?B3C1CE+1?E?*:9DB*::;BDDE><3D@ADDBA;4=)8=(..?D49,'..;6(-;;?5>A?:>(3<;;>???38<9(0529>>?
@78I
AAGCAGATTCAGGTGTTCATTTATGTGTTATTGATGACTCCAATGAGCATATGCTTACTGTATGGGACTGGCAGAAGAAAGCAAAAGGAGCAGAAATAA
+
=;=A72A+,2@<A?<22?73A=ABB333+<7C@C>=1:1=7?A=AB>=B7?40=0*><0**9AA3>B>57=2=5ABBAAAAAA@@@;5666==(;5;;>
@78J
AAGGAAAGAGGAAGTGGAAGAGAATAAAAAAAAGCAAAGCCAAGGAACCTCCTCCTAAAAAGACGAAGAAAAATAATAGCAGCAACAGCAATGTGAGCA
+
?<?DD3B3CCD?3A+2<E9F@E;DBFAEEEADA:9DDB8.BC>ADC@C@CDAD;7?ADDA?@1@>/98;>=<=<:A>A:4>A????8>>>?A>ADDAAA
@78K
AGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACC
+
@@CD?B?BADCCCGGGGD@@CEHG@CFDFEHIE9?DFGE=BGG>D9'@;@8=A;<B@DC>>6;6;;CC@AC?B=?>8ABBBB<A>9CCA@CA@C@AC9A??
@78L
GTACAATGTCAGTGCCTATGATCAGAAGCCACAAGTGGGAATGAGGCCCTCCAACCCCCCCACACCATCCAGCACGCCAGTGTCCCCACTGCATCATGCAT
+
B@BFFFFFHHHHHJJJJJJJJJJJIJJJJJJIJJJFGHIGIJJJJJJJJJJJJJIJJJJHFDDDDDDDDDDDDCD??BDDDDDDDDDDDDDDDDDDDDDDD
@78M
CACGTTTGAAATGAATGGCAAAGCTCTCCTGCTGCTGACCAAAGAGGACTTTCGCTATCGATCTCCTCATTCAGGTGATGTGCTCTATGAACTCCTTCAGC
+
@CCFFFFFHHGHGIJJJJJJJJJJJJJJIGIJJJIJJJJIJJJJJJJJJJJJJJJJJJIJJIJJJHHHHHFFFFF?DEEEDEEDDDDDEDEDCDDDDDDDD
@78N
GCTCGAGAATGTCGCAGAAAGAAGAAAGAATATGTGAAATGCCTGGAAAACCGAGTTGCAGTCCTGGAAAATCAAAATAAAACTCTAATAGAAGAGTTAA
+
@@@<BDA8CF<CFBG@1@FEFHF?FG9*9:C9BB?@B9?FGII4*??DHCGHA8FEHI>7?AEEHBBD:BC3>ACCCCCCCAC@CACC@ACCC:><4:>C
@78O
AGTGTGTTCACACTTTGTCAGATGAGAAATGGGATGTTATTAACTGGAGGAGGGAAAGACAGAAAAATAATTCTGTGGGATCATGATCTGAATCCTGAA
+
?@@DADDDHDHFHIJIJHHHIEHHHHEHFHIIGGIJIIIJIJJIJJIGIJGHIJHGIIEGFHGIJIGHHFHHECEFFFDDEDEDCDCCD@CCCCCCCDD
@78P
CCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTT
+
@@<DD@<+<CFFFGIF9+A1CDGE@EE4CF<9?FDGGFFFEGFII@4??888=7/A?B;;>AC;1;?==9<?<@A?5@(44:@A:>7A3(4>@:A:@A:+
@78Q
AGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGC
+
CCCFFFFFHGHHHJIJJJJJJIJIJJJJJJJJJJJJIIIJJJJJJJJJIJJJJJJJJJHHFFFFFEEEEDDDDDDDBDCCDDDDDDDEDDDDDDDDDDDDD
@78R
ATTATAACCCAGCTCACTGCTAATTTACAACAAGCAAGAAGAGAAAAGGATGAGACAATGAGAGAATTTTTAGAGTTGACAGAACAGAGTCAAAAATTAC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIHIJJJJIJJJJJJJJJJJJJJJJIJJJJHHHHFFFFFFFEEEEEDDDDDDDDDDDDD
@78S
TTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAAC
+
@C@FFFFFHHHHGJIGGHIJJJJIJJJJIIJJIJJIJJJEHGEHHIIJJJJJIJJIIIIIJJJJJHHFFBDEEDDDDDDDDDDDDCBDDDCDEDDDCDDDD
@78T
AAGAATTACAACTTAAAACAGAATTGTTAGAAAAACAGATGAAGGAAAAAGAGAATGATCTTCAAGAAAAATTTGCACAACTTGAAGCAGAGAATAGCATT
+
BCCFFFFFHHGHHJJIJJJJJJJJJIGIIJIJJIJJJJJIJIJIJIJJJIJJIIJJJJJIJIJJIJJJJJIJHGHHGHFFFFFEEEEEEDDDDDDCDDDED
@78U
CAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCC
+
@C@FFDEFGHGDHIJIGJJJJGIGIIJJJGIJJFI>FIIIIIJGEHBHIIHIIEEGEGIEHGGEFFFFFDEDDDDDDDDCDDDCDDDCDDDDDDDDDBBDD
@78V
CCCCACTGCATCATGCATCTCCAAACTCAACTCATACACCGAAACCTGACCGGGCCTTCCCAGCTCACCTCCCTCCATCGCAGTCCATACCAGATAGCAGC
+
?@@DDFBDFHA?DGHHEIIEHIEHGICHHEHBEHE@HGCHHHADFEHGGFGFBGEHHFFFFDBBCCEEBCABB?C@?CC?B@BBCCCDCCCCABCCCCCAB
@78W
CTCCAATGAGCATATGCTTACTGTATGGGACTGGCAGAGGAAAGCAAAAGGAGCAGAAATAAAGACAACAAATGAAGTTGTTTTGGCTGTGGAGTTTCACC
+
CCCFFFFFGHHHHJJJJJJJJJIJIGJIJJJIJJJIIJJJJJJJJJJJJJJIJIIJJJJJJJJIJJJJHHHHFFFFFFFEEDEEDDDDD9ACCBCDDEEDD
@78X
CTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTT
+
@<@DADB>FDDDFEDBG+AEEE:A13AFD>AFFBBFC>F>HGIHBFGCGBHE==8=F>DAF;D@EGGECH>@D>>A@>CC>@CCA>>@C3<<?;@BBBAC@
@78Y
CTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTAT
+
?@1B1;ADACBFDHIDIGCDGGG@BGD@BDGHG?DEC>B@;--7@FB;DDHE7.=;7;>DDCB>CAA==?;3;5>@CCDCCCC@@?8@BB<?28?>B?C@:
@78Z
CTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTT
+
CC@DFDDDHFHFFGHFAGHIIJEGIBHHCHIGCHGHHIC@BGG>DEIHGHG?DFFGBBB=EACHAEHBB@BCE8>BDD?AD?BBDBDBACC@@@CB@39<B
@790
CTGGAGTTTGTCACCAGAGGAGGCCGGATGGACCCACCCAAGAACTGCCCTGGGCCTGCATACCGGATAATGACTTAGTGCTGGCAACATCAGCCTGA
+
9;5(91@<8;;1@<@)(((38:<;(--8=(()))-33=85(.(<))))=7:3:6.6/9(.(.9==;'338(50;=(((,8(3((856<85::<=3/+(
@791
TGTACAAGTACCCTTCTGACATCTCCTACATGCCTTCCTACCATGCCCACCAGCAGAAGGTGAACTTTGTCCCTCCCCATCCATCCTCCATGCCTGTCACT
+
@@@DFFFFFHHGHJJGIJGIFEIIJIJJJIJGIIJJGIIIIIJIEHIJGIJIDCHHIJIEHIGHIIJJGGGHIAEHHFBBEFECEECDDDDDDDCCCDCCD
@792
AGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCAC
+
BCCFFFFFHHHGGIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHGFFFDDEEEDDDDDEDDDDDDDDDDDDDDDDDDDDDDDDDDDDDED
@793
CCCACACCTGGGAAAGGACCTAAAGGTGTATATCAAATCAGCAAACAAATCAAAGCTCATGATGGCAGTGTGTTCACACTTTGTCAGATGAGAAATGGGAT
+
@@@FADF7DFBHBFHGHIEGEBDBBF1?FHGGAEFGGG9BBFGEGE@DDGGCGGIGADHHH=FGHIGCCC?AEE>C@DCB>CCC@CC>>A>A>A?CCCC<C
@794
CCCTGATCATCAGCAAATTCAACCACCAGAACATTGTTCGCTGCATTGGGGTGAGCCTGCAATCCCTGCCCCGGTTCATCCTGCTGGAGCTCATGGCGGGG
+
@?@DA3D?DDFHBHIIIIGDHICB;?<<8<CCCCGIH<CD@:DG@FH9B?;F8==@CAG>EHA?;@;??A?ABBB?<A>>CC:4>(42<<<@>4>C?BB.<
@795
GTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGC
+
@??BDEFFHGHHGGHIIIIIIEGGGHIIIIGHIIDIGGIGIGIIIIGIIIIIGFHHGFFFFFDEECEECCDDDDDDDDCDDDDCDDBBDBCDDDDDDCC
@796
GGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGTTCCAAGTCCATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTC
+
??<DD=D;DD?3AD>EEED:3:A9++AE10:):BD?@*?*?D>DBA*((8=))=AD4=/7).7@)7ACD:7;7@3(6>@@;5>33528??297(+9<(((
@797
CAGAACTTGCAGCTCCACAGGGAACTCCGGGACCCTTGGGTGTGGAGAGGAGAGGGGCTGGGAAGGTTATAAACCAGGTATCTCTACATCAGGATGGCCAT
+
>+1AA32<?CC<<+<7=7??==+?A@>==<:AA?;AABAA/7-7=9A>A<2;2;A='39=:7;58=95;>?:?39;;;3;?:==8=:;3+::;;?;<((+9
@798
GCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACC
+
CCCFFFFFHHHHHIJJIJJJIJJJJJJIIJIIIIIIIJJIIJIJHIIIHIGEHIJJJIJJJGIJJIJJHHHHDFCEFFCEDDADCDDDDDDDDCBBDCDD
@799
CAGTAAGGTACGGAGTAACTGTCCAAAAGCCATGAAGAGATTAATGGCAGAGTGCCTCAAAAAGAAAAGAGATGAGAGACCACTCTTTCCCCAAATTCTCG
+
@<@DDEFFDFDHHEACE?HB@HCHICDAEHB?FGE?D?G@HGIIIGBFHG=GDCFGIIEGGGGB7CGEGCE;?CC>;>?CCC@CCCCCCCCCCBBCCCDCB
@79A
GTCCCATCAGTTTGAACAGTTGTCTGGATCCATTTTGTGGATGGCACCAGAAGTCATCAGAATGCAAGATAAAAATCCATACAGCTTTCAGTCAGATGTAT
+
CCCFFFFFFHHFHGGIIJJJJJJJIIJJIJJJJJIJJGHIGIIIIIIJJJICDHGIIIJIIIJJJJJJJIJJJJJJHHFHGFFFFFFEECEDEEDACDADE
@79B
AAGACAGCCAGTTCGAAACTGATATAGTACAACGAATGGAACAAGAAACACAAAGAAAGTTAGAACAACTCCGGGCAGAGCTGGATGAGATGTATGGGC
+
@<@DDDDFHHGAAACDFHIIICEGIGIDH>GG@GIIIIIIGAHEEEGI9FGHGGEHIIIAHH>GICHH=;ABBECCB?@BCCCC<CC>>:AA::>:?<B
@79C
GAATATGGCATTCTCTCAGTCCAACCCTCCTTCGGAGTTGCACAAGGTCCACGGATCCAGAAACAAGCCCACCAGCTTGTGGAACCCCAACGTACGGCTCC
+
==7+@A7AACB?>CBC>A@AACA@?AA=CCBBBB=AAABBBABBBBBBB>A><A<AAABBBA>AAA@@@@@=@;==?>>55,9;?==;9<<<=;9;;=559
@79D
CAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCC
+
?@@DFFDFHABHHHJIIGGGGIAGHIJJJIGGG<FHG>8:DCGIGHEGGHG>FGHI>GEBEEGCHHHDE@DC@@DCECAACDDDC@A?C>ACCADDECCC
@79E
CAAGGGAGCATCCCCTCAGTCCTCACCATGCCTCAGGAGGTCAGGGCAGCCAGAGAGCATCCCACCTGCTCCCTGCTGGAGCAAAAGGCCCCAGCAAACTT
+
?8=DD1D?DDD>AEA:E?CCEE?F<C>E@BDB?D@D>DDDBB?DBDDD:166=@=CC(.7??==;@AA;3;@55555(;2959<A=>??<8><?<>>>>>A
@79F
CCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCT
+
8?@DFFFFFHHHBFEIIIIIIIIGGIGEG<DGH@GIIDH@FHDGHEIBCCCHIEBGECHGIGDGGIGECHHG@DDFEEEEDEDBC3=?CBABD=B>BCDC
@79G
GGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTT
+
CCCFFFFFHHHHHJIJJJJJJJJJJJIJJJJJJJJJJJJJIJJJJJIJJJJJJJJJIJJJIJJJJJJHHHHHFFFFFFEEDDDDDDDDDDDDEDDDDDDD
@79H
CCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATG
+
CCCFFFFFHGBFHJJJJJIJJJIGGIJJJJICHIIJJJJJIIGIIJIIIJJJJIJJIGGIIJIHGHFF@DDEEEEEEED8@DDDDDDDDDDBBDCDDCCDD
@79I
CATGTATATGCAGAATACTGTCAGTCTAGAGGAAGAGTTAAGAAAGGCCAACGCAGCGCGAAGTCAACTTGAAACCTACAAGAGACAGGAGGATCCAAAGT
+
1+:2<22,2,22<++22+?<<=AC>+?A7<B><?>;=B<AB?BBB<ABB;A<A:A475:A64,,.>@;;5=?=;=9;=999=9;5;=3(22928;=3(38?
@79J
CCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGACCCATGGATGAAGGACCAGATCTTGATCT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHFFFFFDDDEDDDDDDDDDDDDDDDDDEDDDDDE
@79K
ATACGGAGAGCAGTGTGATTCCCTGTGGAGGCACAGTTGCGGCAGCTGCCCTAGAAAAGAGAAACTATTGCAGCTTGCCAGGACCTTTGAGGGCCAACAGC
+
C@CFFFFFFHHHHHIIJIJJJIJJJIJIHGIGJJJJJGIFIJJJJJGIJJIIEHHHHHFFFFDCEECCDCDDDDDDCDDDDDDDDDDDDCDDBBBDD?BBD
@79L
GTTTGGCTTTTCATGGCCTGCCACTGAAAATCAAGAAAGAACCCCACAGTCCATGTTCAGAAATCGGCTCTGCCTGCAGTCAAGAACAGCCCTTTAAATTC
+
CCCFFFFFHGHHGIJJIJJIJIJJJJJJJIJJJJJJJJIJJJJJJJIIIIIIIJIJIJIIIJJGIHIHHFFFFFFEDECECCDDDDDDDDBDDDDDDDEED
@79M
GTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTAC
+
CBCFFFFFHHHHHJIJJIJJJJJJIJIIIJJJIIIJJIHIIJJJJJJJIJIJIIIIJJIGJHHFHHHHFDFFEEEDCEDDDDDDDDDDCDDDDDDDDDEED
@79N
GCTTGGATGCTGGACTTGCAGAGCTGGCTCCTATGCAAGGTCTAGGGTTAGAAAAGCAAGTCCTGGGATTGCAGAAAGGACAACAAACTGGGGGTCGTGG
+
9((5(())2(.;>.244@?:>)6)8))()2=3))1).))(.0.)).90(<9)).).(=9;)63==9;0.8=3)819=39(3;==<5;7(,,6;;5&5800
@79O
ATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCC
+
?@<B=DD>?;ADBEADG4EAHH@GGAGHBD@<FBFBDDGHGGHIIHIEHACHI@FHBGGFG@FGHI@@C=7??C?3?CDECC(;;;A??BBCCCCCCCCCB
@79P
GTGGGAATGAGGCCCTCCAACCCCCCCACACCATCCAGCACGCCAGTGTCCCCACTGCATCATGCATCTCCAAACTCAACTCATACACCGAAACCTGACCG
+
@@@ADDDDDFFHHGDFEFCHEGHIGIIEHIIII9FGF;DCH;AHEFBE7>>>AA@BC@>>A@AC:@@C@ACCCCDDCCC<ACCC@ACDDDDDD<AA?C9?9
@79Q
GACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTG
+
?<@DDF>DHHHHGGIJIGHIJGHGHIDEGHEIJIJJIGG@GHGGIFHIHIIIIGGHIGIJJFFFDDDEDDDCDDBB<@CBCCDCDDDD9@DDCD>A9AB@C
@79R
AGCCAGTCACTGCACCTCCATCCTACACTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGG
+
CCCFFFFFGHHHHJJIJJJIIGHIIIJJEHIGIJJJIIIJJJJJJJIIIJIIFGIGIJJIIIIIGIFHHHHHFFFFFDEEEEDEDDDCBDDDDDDCCDDDD
@79S
TGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCT
+
CCCFFFFFGDFHHJJIJJJJJJJJIJIJJJJJJJJJJJJJJJJJJJJJJJIJIJJJIJJJJJJIJJJJHFGHHHFFFFFFEEEEEDDDDDDDDDDDDDDDD
@79T
GGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGT
+
@@@DDDDDD=FHHIIIFHIGII3<CEHBBEGHEGEFC@4FGIGEEGH'4@ECHE?E=?=DE?@BCCCCCA@C>:@C>?A?35>>@CCCA:@ACCCC?<<@>
@79U
ATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCC
+
::?+ADDDDDABA8EECAF3?CEEE?CE@CDD@3BD<DB096@AA'=(@ADAC;7?@@AAA:.;AA>8=?/5<??(88<A>4(8+(>+4+>(+(+8<(89
@79V
GAAGCTGGGCCGCGCGGTGCACATCATCCAGTCACGGGAGCCCTCCCTGAAGAATTCCAACCCCGACGAGATTGAAATCGACTTTGAGACCCTGAAGCCGT
+
9<58(6>13(.(:5(:=(<9>?<9>?>86=6>>?;???;=26=??==<99;3737===<=<<<605::55:86;=;==36599<=::-8;<<;865+69-8
@79W
CTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCC
+
CCCFFFFFGHHHHJJJJJJJJJJJJIJJJJJJIJJJJIIJJJJJJIHGIJJJIJJCHIJJJHHHGGFFFFFEEEDEDDDDDDDDDDDDDDDCDEDDDDDDD
@79X
GCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGGGTTTATGGGCAGG
+
@@@FFFFDHFHDHCFGF9ECIGIHHEHIHICG<DGGHFEHGGGIFBHGIGEE@FH@CFHDHIHFDEDAA?CB?B<BCCCDADDDD(50<8>CCC?BABB
@79Y
AATCTCCTTATCATGGGGACTGAGGATGCCTCCTCCTTGCCTGAAGCCAGTCAAGAGGCAGGGAGCAGAGGCAATTCCTTTTCTCCTCTGTTGGAAACCAT
+
@@CFFDFFGGFHHEIIJDBGFGHIJJJJJJGGGIJJJJJJJIIIJIIJGIJJJJJJGIGGIIIFFGFFEDDDDBDDDDDDDDDDDDACDDACCDDDDCDDD
@79Z
TGAGAAAGGAATTATGCAAAAGGTGGCTGGAGAGAGATATGTCTACAAGTTTGTGTGTGATCCAGAAGCCCTTTTCTCCATGGCCTTTCCAGATAATCAGC
+
;@@DDBD?A?CFF<FFBGFHEGE<CG;C@GBF?DAFBG99B?GHIIIFHGHDGBC=B8CG>=C=@AGHECHEHFC;@;@>@C@BAC>;>ACC>:A@>ACCC
@7A0
GTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTAC
+
=+=AAA7??CACBBBBBBBABAB=3C;C<?BAAAAABBBAAB<7=3ABBBA2..8==A7>B7AAAA>A@;>>>>>>(6;;;====999=:=<<<=?=????
@7A1
AGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACC
+
?<;ADDDDHHFHHIGIGGIGIEGCHHCGG?E<::::C?CFFDFGFIIDAFHGG;@;=BFHGGCCH;CG?EHEDDF7?>>A(.6=BC@@A>CCBA>98ACC<
@7A2
CAGGAAAGCCTACAAATTTATTAAGGGAAGAAGAATTTGGTGTTGATGATTCTTATTCTGAACAAGGAGCACAAGACAGTCCGACTCATCTAGAGATGATG
+
@<@ADDDDH;DBHIEEHBBEBAFFHCGI<DGCG>BAGEGI::06DH*?FB?*BB<DD<CCDGIIIIGHIBDEHHHBADC@BDAC@;>CC@AC@CACCCADC
@7A3
GTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGC
+
CCCFFFFFHDFHHGJJJJIBHHGIIHIIJIIJIJIIJIJIJJJJIGIJGIJHIJJJJJJJIJJHHHHFFFFFFEDEEEEDDDDDDDDEDDDCDDDDDDDDD
@7A4
TGTGAAATGCCTTGCTATACATCCTGACAAAATTAGGATTGCAACTGGACAGATAGCTGGCGTGGATAAAGATGGAAGGCCTCTACAACCCCACGTCAG
+
@C@DFFFDHHHGFGGJJJJJIHIEGHIEGHJIJJJIJGIIIJJJJIIJJHIIJHJGGGGHGIFHIJJHHHGGHHFFFFCDDCCDDDDDDDDDBBDA?DD
@7A5
GCCAAGCTTGCCCAGTTTCGACAAAGAAAAGCTCAGTCGGATGGGCAGAGTCCTTCCAAGAAGCAGAAAAAAAAGAGAAAAACGTCAAGCAGTAAACATG
+
@CCFDFFFHGHHHJJJJJJJJJJJJIJJJJHGGHIJHJIIHEIIJICGHIGGGIIJIGHHHHGFFFFFEEEDDDBBDDDDDDD@ABBDDDDDCDCCDDCC
@7A6
CTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGAGCAGGCATATGGGCAACAA
+
@C@FD:BDFHH<?CFHEAHIIAFH@@?GFHGICBGFBDFHHHI>BHHGCGHHHEDDDEBEECECCC;CCCAAB9?@BBC<ACACBCCCC@ACBCCBBBB
@7A7
CACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCA
+
;?@DBDB?DDAH?<EBBBEGHGGHIIIGHIIFIIIEGCFEAH>FCCHGGIHIEEHIIBGGHHHCHHEEDBDC@CCB;A???BC<AC@>@CCDCECC:@C:
@7A8
ATCATGATCTGAATCCTGAAAGAGAAATAGAGTTTAGTGCTTCAAGGGCCAGGCTGCCAGGCCATGTTGCAGCTGACCACCCACCTGCAGTGTACCGCCGG
+
@C@DBFFFHHGFHGGGHHEHJEBFGIGHIIGBEHHEH?FEGGHEGGEIIJJIJIIJGGGGGIJGECHIGGCHFEEHEEFFFD;ABBDB?CACC@DC@BD@B
@7A9
GTTCGCAAGTGCAAGCCCCAGATGAATTACGACAAGCTGAGCCGGGCCCTGCGCTATTACTATAACAAGCGCATTCTGCACAAGACCAAGGGGAAACGGTT
+
?8?BADDD8:A:DBF:<ACBEBDECADFFCEEEGE>FF>@;B;;<5ABA=>;BC>@B>>ABDDBBAA@5<?BB@B<4A@@AB@<@?BB?BBB<@BBBBB0<
@7AA
AGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCC
+
C@@FFFFFHHHHHJJJJJIJIIIIJJJJJEHHIHIJICIJJJGHIJIIJJGJJGGIIIIJJJJJIIJIHHHHGFFDDDEDDDDDCDDDDDDDDDDDDDDDD
@7AB
CAAGGCTTTAAGCAGGAGTACCACGACCCAGTGTATGAACACAACACCATGGTTGGCAGTGCGGCCAGCCAAAGCTTTCCCCCTCCTCTGATGATTAAAC
+
CCCFFFFFHHHHHJJJJJGGIJJJJJJJJJJIJIIJJJJJJJJJJJJJJJJJHIJJJJHEHFFFDDDDDDDDDDDDDDDDDDDBDDDDDDDEDEEEEDDD
@7AC
GGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTT
+
CCCFDFFFHHDHHJIHIIJJGGIIIFIGJIJIGIIJJJIGGGIGHIJJIIIHJIJJGHIHGIIGIGEEHHHHFECBDFDEDDDDDDDDBCCDDDDDDCDD
@7AD
CTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGC
+
@C@FDDDD?FFFDGEIEHIIIJGIGHHDH@FFEECHEIIJJGFEGIJJIICFC>FHIJIHGGIIGH=EEFFF>CDEEDAC@CDCCA@B?ACACCBAACCC
@7AE
GCAGTCAAGAACAGCCCTTTAAATTCAGCTATGGAGAAAAGTGCCTGTACAATGTCAGTGCCTATGATCAGAAGCAACAAGTGGGAATGAGGCCCTCCAAC
+
881=4=2AACDD;;E?EC333AF@@?<ACA<?E>E9?D@DC:*:?9BDD9<9B9*??*//8B).=.=@C4.7@AC=C6(?....(6;6;@>A7?==<,9AA
@7AF
CTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGC
+
@@@FFFFFFHHBFIIJHIIIJJJIJGDGHIJGEEGHIIJIIIFDHIIGIJIGIIJEIIJJJIIIIFHHHFFFFDDECCECEEDDCDDDDDDCD@BCDCAA
@7AG
CAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGC
+
@@?DFFFFHHGHHIEGGI@DGI;F@FHFHG@FGEFAFECH;BGFEGIGIHHGGGGEEFGHHG@E=EEHECDB>CBCCEDCC:5=@?B5>A>@BCBC@A
@7AH
CCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACA
+
@@?DDBDDBHA8FB:1CFGIIIIG<CGGHB>HGGGEGGGDGG@GGHIIFGE>DHHGH@>CECCGHBDEC>@CCA>C>CC?BC?CB@CCCCDC@CC:@CCC
@7AI
CTTGGGGAATGGAGATGTTCTTACTGGAGACTCAGGTGGAGTCATGCTTATATGGAGCAAAACTACTGTAGAGCCCACACCTGGGAAAGGACCTAAAGGGG
+
CC@FFFFBABHHFHG@ECHHCHHHIGGFHIFI@FFH:DDHGDGIJJJGEHJJHDB=2BFHGJCFGHGHIIGCEA>;;5==BCCBB;?BBB<9<?>:CCC(0
@7AJ
CTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCT
+
@@@DDFFFHHHHHIIIIEHGGIGGEGGIEHGGIIIFIGIHIIIGGGEEGEGGHGGCGCGGGGIIIIIHFAEEDFBCB?CCAC:@C>ADC:>>>C>CC@>:C
@7AK
CTTTTATGAGATGGCAGAAAGGTTCATGGAGTTTGAGGCTGAGGAGATGCAGATTCAGAACACACAGCTGATGAATGGGTCTCAGGGCCTGTCTCCTGCA
+
@@CFFFFFDFFHFGGGGHHGGGEHHGGIIFCDGGCAGHDFGEHIFIGGGIIJABCHIIAGEHIIB@@;?CAEA7??BCE>CEECCDD@??B>ACC@CDCD
@7AL
ATCTAAACTAGAAGGTCAATTAGAATCTTATAAAAAGAAGCTAGAAGACCTTGGTGATTTAAGGCGGCAGGTTAAACTCTTAGAAGAGAAGAATACCATGT
+
@@@FDDDDFHGHGIF<ADAIGHA@BHBCH@HICGGFHGIGEFGIGIIGGIIDED*7??DGFG>ACEGBBCB=>CCCCACCCC:>@>><CCCC>CCCCCC@4
@7AM
CCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATG
+
@@@FFDDEHFFDHGHIJJIFIIJJJJGGIIEHGIGIICGEHIIJJJIEGIJGGIIJJJIIGGABEADFBDDDEEEEEECDDDDDDBDBBDDDBDCACCDED
@7AN
AAAGGAATTATGCAAAAGGTGGCTGGAGAGAGATATGTCTACAAGTTTGTGTGTGATCCAGAAGCCCTTTTCTCCATGGCCTTTCCAGATAATCAGCGTCC
+
CCCFFFFFHHGHHGHIJIJAEEHHIIIJJIIGHHIIJGIIIJJFIFGGGIGFHGGHGIJJJGGIJJJIJHHGDEEEFFFFECEDDDEDDDDCCCCDDDBDD
@7AO
AATCACTGCCCAGCGTCCTCCGAGTCCCACCCGAAGCCATCCAGCCCCCGGCAGGAGAGCACACGCGTGATCCAGCTGATGCCCAGCCCCATCATGCACCC
+
;?<DD>D4?DD3<CECEEDEFEEE1EEEEII?@DDDDDDIED3=ADDAIDD@@?>>?=??A<??>>?)8<(:>>3>:>A>>AA<(8<??????AAAAAAA?
@7AP
CCGAGTCCCACCCGAAGCCATCCAGCCCCCGGCAGGAGAGCACACGCGTGATCCAGCTGATGCCCAGCCCCATCATGCACCCTCTGATCCTGAACCCCCGG
+
@@@DD??DFHHFFBGIEHIGHF?<FGICF?FGIIHI=C@CEHFFHBEC?B?C@@>CC:@>>>:@?ABB@?>BCC@CA>CCCBB<?C3@CACCCCCBB@BB>
@7AQ
GACTTCACAATGCAAATTAGTTTCTTGCAAGAGAAAATTAAAGTATATGAAATGGAACAAGATAAAAAAGTAGAAAACTCAAATAAAGAAGAAATACAGG
+
@C@FDDADBFHDBGIIIIIIBHHHHBCHIHIACCD9EFCEDHI?FGGG@GIIIIGBG?FG@;=CFHEFGG@=;DHAE;C;?BC;>CE@ABC>C=AA:;@?
@7AR
TGGAGGCTAAAGATAAGCAATTTAAAGAAAATTTTAAAAGGAATCTTGGATTATAATCATGAGATTTTAGGACAGCAAATTAATGACTTTACCCTTCCTG
+
=+=DBAD;D?<A+<AE<C<?CFEFCFI<FE?E<B?E?BD<8:BDE>>?B3?DCEBDDBE=CB@BBCIEEDE47ACCCDCACA?AD;@@AAAA>A>;5;AA
@7AS
TTTCCAGATAATCAGCGTCCACTGCTGAAGACAGACATGGAACGTCACATCAACGAGGAGGACACAGTGCCTCTTTCTCACTTTGATGAGAGCATGGCCT
+
@@@BDDDDFHFHBIEHGGCEGFHAGIGI@CFCEHI>GHEBABFI@G=BFFHIGEGGB<AC<?CEFFEFFCECCEEDDCC>@@CCDDDCD@CC?CD@BDDD
@7AT
TCACTAACTAACGTGAAAGCCTTACAGAAATCTCCAGGACCTCAGCGAGAAAGGAAGGCATCTTCATCCTCAGAAGACAGGAATCGAATGAAAACACTTGG
+
?8=+=DD+ADDD;<AAEE?+AA3C9A9AC9C?E<<:C;C88;DD@@86:ADE@6@D@(.=.=7;7=;?>>;.7@AAAAA=;??3;9?AAAAAAA3<((44>
@7AU
GAACAGAATAATAACGTAGCAGAAGCTCAGGAAATAGAAACGGGCTGGGGTATGGTACTTGGGATCATGATAGTTGGCGTAGGTCTCCCATGCCTACGGAT
+
1+12+++++++2<=7+2+++,33+2222+1:*1**7**1**)0))(0(('-'))).))))))((.(5))).(.(((((,''3((,(((((+((((((&)0)
@7AV
GTCGGAGGAAGAGGACAAGTGCAAGCCTATGTCCTATGAGGAGAAGCGGCAGCTCAGCTTGGACATCAACAAGCTCCCCGGCGAGAAGCTGGGCCGCGTGG
+
B@CFFDFFHHHHHJJJJJIGIJJJJIJJJJJJJJJJJJIJJJJJJJJIJJIHHHHHFFFFFDEEEEDDDDDDDDDDDDDDDDDDDDDDDCDDDDDDDDBDD
@7AW
CTCCTCTGATGATTAAACAGGAACCCAGAGATTTTGCATATGACTCAGAAGTGCCTAGCTGCCACTCCATTTATATGAGGCAAGAAGGCTTCCTGGCTCAT
+
@@@DDFFFHFHFFIIIGIJJGIJJJJGIJGHGIHIGEGGIECIGIEIIHJIDGHHIIEHIJICHCECGEHCHGIBH>EHF?DB?DECDDCCCC>CDD3>>@
@7AX
TATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATC
+
?<@DADD>D=:AD>B:?<FFFIIIAFGEIE9@?9?8?0:?GBDFFCFE??8<BBB=3==8=;@3=CF;A?>@B?B;A@CC@?>;;=@;/;=B>A>ABA@A
@7AY
CTCAAAAAGACCCTCACATGATCCAGGGAGTGCAAGGTCGAGTGCTGTGGCTAGTTGAAAGGCCACAGCATCGTGACCGGGAGGTACACTATCAACGCAGG
+
0-((2).(-(2)()2(()));))29.)(((-())200))80().).0)))(()())./<1)((((869().(,.9(91,'',&0+(+2((((((+(&&&)0
@7AZ
CTGGCTTACATGAACCACATCATGGTCTCTGTCTCCCCGCCTGAAGAGCACGCCATGCCCATTGGGAGAATAGCAGACTGTAGACTGCTTTGGGATTACGT
+
@@@DADFFHHDFHIIIJIHIAHHEIIIIIJFEG@@C@FHIJGIGJIIEHBHA<HGEGIHIEHHHFEFD?ACC>C@>?ACD@B@@CDDCDDCCCDACCCCBB
@7B0
CCTCGAGCAGTTATTCCCATGTCCTGTATAACCAATGGAAGGGGTGCAAACAGAAAACCAAGTCATACCAGTGCTGTCTCAATTGCAGGAAAAGAAACTCT
+
1?@DDDDDFDCFFF>DG<EHIC:AFD42<CAC<EAFAEEEE76@?@FCDD2B;CFA@@EEE;AEEEC;;;>))6.(...5;;>(>AAAB@9AB5?B<94::
@7B1
CATAACCCTCCCACCATTGAACTGTTGCACCGCTCCAGGTCACCTATCACGACAAATCACCGGCCTTCTCCTGACCCCGAGCAGCGGCCCCTCCGGTCCCC
+
CC@FFFFDHHHHFIGHHJJIIJJIAHEHJJJIGBHIHGIII@FHIIGGGGIHIGHHEHGHHEFDDDDDCDDACCCCDDDDD>BCB@<BDDD<@D3>9@BBD
@7B2
TTGAGCTGCTGGCCCGCTCATTGCCAAAAATTCACCGCAGTGCATCAGAACCCTCCTTGAATCGGGCTGGTTTCCAAACAGAGGATTTTAGTCTATATGCT
+
;??DB;;AF<A:1AA@:<<C?CCBBFDGIF@DGEEIC6D?F@FC=B==FDFD@@DEEFCEDDFDB?CB@BBBB>A>@A?BB99<(3>>ADB4>>44@BB>>
@7B3
CAAACAAGAGCCAGGAATGTATCGGGAAGGACCCACATACCAACGGCGAGGATCACTTCAGCTCTGGCAGTTTTTGGTAGCTCTTCTGGAT
+
CCCFFFFFHHHHHJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJFFDDDDDDDDDCDDDDDDDDCD?CDDDDDACDD@CDDCDDDCA
@7B4
CCTTACAGAAATCTCCAGGACCTCAGCGAGAAAGGAAGTCATCTTCATCCTCAGAAGACAGGAATCGAATGAAAACACTTGGTAGACGGGACTCGAGTGAT
+
CCCFFFFFHHHHHJJJJJJJJJJJJIJJIJJJJJJJJJIIJJJJJJJJJJJJJJJJJJJJJJJJJJHHHHHFFFFFDDEEEDCDDDDDDDBDBDDDDCBDE
@7B5
GGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJGIJJJJJJJHJJJJJJJJJIJJJIJJHHHHHHHFFFFFDDDDDDDDDDDDDDDDDDCDDDDEDDCDDDDDDDDDD
@7B6
AGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGC
+
@@CDDFFFBHFFBBC>GC@HHBGG@:EG@EFCFBFGIIGEECCCGGIGGGGIGIA;BE8B?B@;@CCECC?9=?A?<@@@@CCC?CCDCCBCCCCCCCCAC
@7B7
CCATACCCCAGCAAAAGCAACCAGGAAGTTCTGGAGTTTGTCACCAGTGGAGGCCGGATGGACCCACCCAAGAACTGCC
+
@@@DDDDDFB?DC@FBHGIGIEH;EEGGECBG>>4?0??BB?DDHEH@F@BAHGHGIBEEEDEEB;?A?=A;BCAC@CC
@7B8
ATGAAAACACGGCATAAGGGAGAAATGGAGAATGCTTTAAGGTCATATTCAAATATTACAGTTAATGAAGATCAGATAAAGTTAATGAATGTGGCAATAA
+
CCCFFFFFHHHHHJJJJJJJIJJJJJJJJJJJIJIJJJJJJJHHIJJJJJJJJJJJJJJJJGIJIIJJJJHHHHHFFFFFFFEEEDEEEEDCEDDDDDDD
@7B9
AACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTAC
+
@@@FFADDFHHFGGIJIJJIJJGIIJIIIIGGHEDHIEIJJFIGIJIIIJJEHEIJJJJJFIGHHE?B@FFEDCEEEDDDD(;@CDDBBCCCDDDDDDCCD
@7BA
CAAGCCCTCGAGCAGTTATTCCCATGTCCTGTATAACCAATGGAAGTGGTGCAAACAGAAAACCAAGTCATACCAGTGCTGTCTCAATTGCAGGAAAAGA
+
CCCFFFFFBHHHHJJJJJJIIJJIIIIIJIIGIIJGGIJIJIJGHJIHI>FHGIGEECHIIIJEGIFEHGGFHFFFCDAEEEEDDDDDEDCCDDBDDDCD
@7BB
AGGAACTAAAGGTGTTTATCAAATCAGCAAACAAATCAAAGTTCATAATGGCACAGTGTTCACACTTTGTCAGATGAGAAATGGGATGACATTAACTGG
+
(0(:2(<4)4=??)@()=4@>?>4)3282.@>?78);><?8).).0)033)(0))0030/69...)6.)..31;)8)).)<>8)(8)((((..693(--
@7BC
CTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGC
+
@@<D;DDDH??BFBC?FHIGEHGEEE@FGEEF>BHFGGGIIG?3B>DFG89=FA>FHDCFAGIG;C;EH@CCC@DCC>.66;@CC=?;5<@5@C?9??CC
@7BD
GGGCGTTCGCAAGTGCAAGCCCCAGATGAATTACGACAAGCTGAGCCGGGCCCTGCGCTATTACTATAACAAGCGCATTCTGCACAAGACCAAGGGGAAAC
+
CCCFFFFFHHHHHGHIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHFDDEDDDDDDDEDDEEDDDDDDDDDDDDDEEDDDDDBDDDDDDDDDDDDD
@7BE
CAGGTGGAGTCATGCTTATATGGAGCAAAACTACTGTAGAGCCCACACCTGGGAAAGGACCTAAAGGTGTATATCAAATCAGCAAACAAATCAAA
+
?@?BA?D?FAFFHGGD@EHAHGAAGDHCGC>CFE<?:C<@B<?FDB6?)8BFABDH<F>(6CHIE>>?7.=;77?;;@BCACC>CCBBBBCC@CC
@7BF
TGGGGACTCACTTGGCCACTGGGGAGTCAGATGGAAAACAAGAGGAAGAAGGGCAGCAGCAGGAGGAGGAAGGGATGTATCCAGATCCAGGTCTCCTGAGC
+
<@@BDDDDHHD??GGIIEIIGGII=CDFEEHGIIIIGI@FHIIHHGGGIIDFHIIGIHFHHHE=;AACBBBB?B@C?@C@DCCCCCCCCCC4>>ACCCCCC
@7BG
ATTTCAGCAATTACAGGCTAGTGAAACTCTGAGAAACAGCACTCATAGTAGCACAGCTGCAGACTTACTACAAGCCAAACAACAGATCCTCACTCATCAAC
+
<@@?DDADDHGHHBEHIGIEICEAE@HAEGBDGFH@AHGIDCGCHHGHF>?GGGGGGBGGGGIBGIGDEGIIIGGHHEADFF??BECECCCCC5@?AC>CC
@7BH
CGCAGAAAGAAGAAAGAATATGTGAAATGCCTGGAAAACCGAGTTGCAGTCCTGGAAAATCAAAATAAAACTCTAATAGAAGAGTTAAAAACTTTGAAGG
+
CCCFFFFFHHHHHJJJJJGJJIHGJJJJJJJJJJJJJJIGIHIIIJJJIHIJJJJIJJJJJJJJJJGHHHHHFFFFFFFDDEEDCDDEDDDBDDDDDDDD
@7BI
ATGGGCGGCTTCGGCCCTCACCTGGGCTTCAGGGGGCTGGGGGCGCCGCTTGCCTTGGAAAGGTTTCTTCTTCAGGAAAACGGGCAAGAGAAGTGCATGGT
+
@@;DDD>DDA??FDBE@G?B?DFGHIG;FGA>GEHHCCCB@BB=5-55@<BB??33@C:ACB<:@A44:@:>A4ACC@C?39?B@>B(++9A9+:(:4@B4
@7BJ
CTGATTCAACCAATAGCCCTGGCCGTACGCCTAACCGCTAACAATACTGCAGGCCACCTACGCAAGCACCTAATTGGAAGCGCCACCCTAGCAATATCAAC
+
1++442222=2?2<E+:C3+3<AE)2):)?:B6:?98@:;@BD)8=38)4AC>:16;@2?;,3('',599((,:>A:3>9<53&5-(0+3(4>:+((:(:<
@7BK
CAAAAGATAGAAACCATGCAGTTTGAAAAGGACAATTTGATAACTAAGCAGAATCAATTAATTTTGGAAATTTCAAAGCTAAAAGATTTTCAGCAGTCTCT
+
:+:@AA==4+<>>;@+<=AABA@B4?4++<<ABABBBBB>><?ABB9A:A;A3?A4=AA<=>B===6A7777>))=>=AA>A>>)=;>>(6>>@9(5;?=5
@7BL
CAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATAT
+
CCCFFFFFHHHHHJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJIJJHHHHHHFFFFFEEEEDDDD?BDDDDDDDDDDDDDDDDDDDDCDD
@7BM
CACCGAAACCTGACCGGGCCTTCCCAGCTCACCTCCCTCCATCGCAGTCCATACCAGATAGCAGCTACCCCATGGACCACAGATTTCGCCGCCAGCTTTCT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJIJJJJJJJIIJJJJIIIIIHHHHHHFFFFEEECEEEDCDDDDDDDDDDDDDBBDDDDDDDBBBDDBDDDDDDD
@7BN
TCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACT
+
CC@FFFFFHHGHHJJJJJJJJJJJJJJJIJJJJJJIIGGIJJJJJJJJIJJJJIIIJIIIJIJIJJHGHHHFDDDDBDDDDDDDDDDDDDDDDDCDCCD
@7BO
CTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATG
+
CC@FFDEDHHDHHJJJIIGIJGHIGGIJIJIAFBDGGIJIIIIIJIHIIJHHHHFFFBDCEEEDCDEDCDDDDCBDDB@<ABDDDDDDDDDDDDDDDCDDD
@7BP
CCGCACCTCCAGCTCCCTGGACCACCCGGATGAGCGGGCCCTCACCATGGGCGACCTCATCTCATTTGCCTGGCAGATCTCACAGGGGATGCAGTATCTGG
+
;;3(-(()(.9)@@@45.8(:>=@11>??3=2)=)93''-'.99==8(..3;/','3:2632:/32622+222288<;5;((8/222)&)+8(+8((+862
@7BQ
CCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJIJJJJJJJJIGIJJIJJJJJJJIJJJJJJJJJJIJJIIHHGHFFFFDEEDDDDDDDDDDDCDDDCDDDD
@7BR
CAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAAC
+
@@?D;DDB?ADCAF9@?:CEFG?B?GGEEICAF@>DFF@F*?DDDGACFF;8C@F<C=@@=2@E5;>?A;;7;?BCAABCC<A25?5955@(,5(55@:AB
@7BS
CGGACATCAGCAAAGACCTGGAGAAGATGATGGTTAAGAGGAGAGACTACTTGGACCTTGCGGCGTCCACTCCATCTGACTCCCTGATTTATGACGACGGC
+
???:DDD?:C8FFIG9;EGGH3<CGD;CGFDFGCDDCH>F;:D)?GHB@DF@GHIIIIGIFHGH>3>B8>@??>ACCCCC:C@<CC?AA>4(:44<25<B>
@7BT
TACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTT
+
CCCFFFFFHHHHGJJIGHIJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJIHHHHHFFFFEDEEEECDDDDDDDDDDDDDDDCAD
@7BU
CTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGC
+
:?@DDBDA>CBF?G@FIIIEIHEB>;FEDHHGGF@F>FG?BDH9BGF@HGIB=C@;CCAGGG@;CAE=?E:B@;?);CCCCCCA=@C::>>999?@?BB9>
@7BV
CTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTAT
+
@@@FBDFBB?FHHIDHC@FD?FHB<FHIGGHE;FHIIGHGFHB@D>CEHGHHC?CEEEFFDDDAC;@CBBCCCCCCCCCC:>A5?@8<@BBBBBBC@BCCC
@7BW
CCAGTGCCGAGTTACGCTTCCTCGACGCCACTTCATGTTCCAGTGCCTCGAGCGCTCAGGATGGAGGAAGACTCGATCCGCCTGCCTGCGCACCTGCGCTT
+
@@<DDB?DFHF?FEFEH@FHIIGGIAFHGIGGGIGEHHGCFB@FCHIFG@A:EDFCDDAC>CABDB?<BA?CCDBA?BB@BDD<??CCBBB0<BDCDBBBD
@7BX
GTTAGCCAAGAAGAAAGATTGATTTTCTTAGACTCCATTAAGTCCAAATCCAAAGACTCTGTGTGGGAAAAAGAAATAGAAATACTTATAGAGGAAAATG
+
@@@FFFFFFGFDHGHGCHIJGJFIJGICEIEHEEIJIJJJJJHHIJJIHJIJJHIHGIA@HDGFHGHHIIGIIGHGDFFCCEFFEDDE@CECDDDDDDDD
@7BY
CGAGGACGGGCTGCATAGGGAAGGGAAGCCCATCAACCTCTCTCATCGGGAAGACCTGGCTTACATGAACCACATCATGGTCTCTGTCTCCCCGCCTGA
+
@CCDBADDAFHHHFBEEFBEGDFHGIGGGEDHGGGHGGGIIGGIIGIIGGEHBBEF@CAEC@CDCDDCDDDDDDCC@CCACCCDCCCDACDDD9<B@AC
@7BZ
GGATGCTGGACTTGCAGAGCTGGCTCCTCTGCAAGGACAAGGGTTAGAAAAGCAAGTCCTGGGATTGCAGAAAGGACAACAAACAGGG
+
@@<DDDDDBFFHHGIIBHGH>FCAFAFFHIIIDIGEHICGEG=?BFHGHBF=ADEH@@FFGFE@GDE>A?>EBCDE@AACA???=;98
@7C0
CCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTAT
+
@@@FDFDFGHHFHEIIII@BHIBGII<GIGGGHCDFHIIGIJGGG>FEECGHHHBDBDFECE:@@>CCCCDCBB??@=B<@?B>@>:><ACB8ABDD?ACA
@7C1
CTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTC
+
@@@AB:2AC??<FA?:AA3AAEHIEIEHBHIFGB3?)CGBG9*)0:8@GCFB8DFF9FEDFFFAC;@=D:?EA?@BBB?ABCCAA=>==BBB?>>?:@AA>
@7C2
GCCAAGGGAAGGACGTCCTATGTACCAACGCCAGATGTCTGAGCCAAACATCCCCTTCCCACCACAAGGCTTTAAGCAGGAGTACCACGACCCAGTGTATG
+
CCCFFFFFHHHHHJJJJJIIJIIIJJJJIJJJJJJIIGIIIIJJIIJIIJJJJJJJIHHHGFFFFDDEDDDDDDDDCDDDBDACCCDDDDDDDDDCCCDEE
@7C3
CAACAGGGCAGAAAATGTACAGTCATGTGATACTCAAGTAAGCTCTTTATTAGATGGAGTTGTGACTATGACAAGCAGGGGTGCTGAAGGATCAGTTTCT
+
@@@DFFDFDHHBHHII<HHIIIEFHIEHGGIIIIIGIIGGGHG@EFIIIIIIIGHIGIIDFG=BGEHICGGIIIIIGCHFEBABCCCCCCBCC?ACCCCC
@7C4
CAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTC
+
CCCFFFFFHHHHHJJJJJJJIJJJJJIJJJFHJJJJJJJIJIJJJJJJIJBFGIJJJJGJIJJJJJHHHHFFFFFEEEEDECCDDDDCDDDDDDDDDDDCD
@7C5
GAAAAATAATAGCAGCAACAGCAATGTGAGCAAGAAGGAGCCAGCGCCCATGAAGAGCAAGCCCCCTCCCACGTATGAGTCGGAGGAAGAGGACAAGTGC
+
?<<DDEFFDDHFHFEB>BFE:FFHEDHG>AFG@FIGAH@FCDGCGGDIIIHE>8=;C>EHGCACDD<>B@(;353:<3:5@??599?<<A<A<A<A8@>C
@7C6
TCTGGATCCATTTTGTGGATGGCACCAGAAGTCATCAGAATGCAAGATAAAAATCCATACAGCTTTCAGTCAGATGTATATGCATTTGGAATTGTTCTGT
+
@B@DFFDDHFHHGDICGHHGIIFGIJGIIIIHGGIGJJJIJJAHIGICHIEIGIIJIJJJJGDHGGEHGGGIIHGE=AE@EHFFFFFFFFDEEEEEDECC
@7C7
GGCAGTACTCAGCAAGGTACAACTATTCTTCAGTATGCACAGACCTCTGATGGACAGCAGATACTTGTGCCCAGCAATCAGGTGGTCGTACAAACTGCATC
+
CCCFFDFFHHHHHIIJJFHGIJJJJIJJJJJJJEIIJJJJIIJJJJJJJIIJIIIJJJJIIGIGJIDFHIJJJJIFHCHHHF;BD=CD>BDBDDDDDDDCC
@7C8
ACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGC
+
CC@FFFFFGHGHHJJJJJJJJIJGIIJJJIJJJJJJJIJJJIIIIIIFIJIJGGIIEHIJJIIGGGIIEBHCFFFFDDCEDDDCDCCDDDDDDDCCCCDD
@7C9
AAGGAAGATTTAGAAATTGAACATCGAATAAATATTGAAAAACTTAAAGATAATTTAGGCATTCACTATAAACAGCAGATAGATGGTTTACAGAATGAAAT
+
@;@AAB??CDF<CBAFB@HEEBHHGGGGFHG@FHGH>B<@CCDFHII9@DD@D@?*9BFE<<FHGGCC@GHICC>D=9A)=3=??C;BBCCC@@CCCCCC@
@7CA
CATCAAACAAGAGCCAGGAATGTATCGGGAAGGACCCACATACCAACGGCGAGGATCACTTCAGCTCTGGCAGTTTTTTGGTAGCTCTTCTGGATGACCCT
+
CCCFDFFFHHGHHJJJJIIIJJIIJIIJGHIJJJJJJJJJGIJFIIEHIGADDDDCABDDDDDDDCDD<CCDBCDDDDD@BBCCCCCDDCCCDACCCDDDD
@7CB
CGGACAGTACATTGCCATTGCCCCAAATGGAGCCTTACAGTTGGCAAGTCCAGGCACAGATGGAGTACAGGGACTTCAGACATTAACCATGACAAATTC
+
BC@FFDFEHHHGHJIGIHIIJIJJGGJIEDGIIIIJJIDG>DBHIGIIJIJJJHCGCHCA@GAHGEHIHJGHHFFF@EFEEEECEDCCC@CC@CDDDDC
@7CC
CAAATTCGAGCATCACCTTCTCCCCAGCCCTCTTCACAACCTCTCCAAATACACAGACAAACTCCAGAAAGCAAGAATGCTACTCCCACCAAAAGCATAA
+
CCCFFFDFDFHHHJJJGHIJJIHGIIHHGIJJGJJGEHIIGHJGHEHIJJIGIIJIJIGHHJJJJHGHHHFFFFFDEECEDDDDDDBDDDDDDBCDD>AD
@7CD
TCCTACTCTTCATGGGCTATTCCACAAAGCCACAACTGGCTATTGTTACCCAGTGGTGTGAGGGCTCCAGCTTGTATCACCATCTCCATATCATTGAGACC
+
@CCFFFFFGFHAHIJEHFHIIJEEIGGIGGGIEHGGIIJEGGHHGGIJJIIHHI>F=BFB>FECGCGEHHGDHFBDFE;@A>A@>C@CC@CDDCDCDCDDD
@7CE
CCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCG
+
CCCFFFFFHHHHHJJJJJIJJJIJJJJJIJJJJJJJJJIJJJJJJJGHJIJJJJJCHIJIJJJJJGHGHHFFFFFFDDCEDDDDDDCCDDDDDDDDDDDDB
@7CF
GGAAAGTTCACTGCTGGCCTATAATACAACCTCTCACACCGACCAATCCTCACGATTGAGTGTCAAAGAAGACCCTTCTTATGACTCAGTCAGAAGAGG
+
@@@FFFFFFHGHAGIGHIJIIJIIJGIIIJJFGIIGGGGIFGGGHIIGJJJFIIIIE@EEEEHGFHHEFFDFDEDEDDDDDDCDDDDDDDDDCDDCC<<
@7CG
TTTGTTGGCAGAGAATCAGGTATTAATGGAAAGACTCAATCAATCTGATTCTATAGAAGACCCTAACAGTCCAGCAGGAAGAAGGCATTTGCAGCTCC
+
@@CFFFFFHHHHHJJJJJJJEGHGJJJJJJJJJIJJJJJJGIGIIGGGDHIIGHGIHIIHIJIIIJIJJEHGGHIEEHEFFFFEDCEEDCDCDDDCDD
@7CH
CAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCAC
+
@?=1DD8@FFBF<E<?CD?:AFBGEHIIIIGEHII9BDGGIEICHGGEHFD@DHI;CHCEB?D>>;ACC>?B??@BACCC@>CCCCBCC>CACCCBBB@BB
@7CI
GTCCACACTGCGTGAGCTGGAGCGCTATGTCACCTCCTGTTTGCGGAAGAAAAGGAAACCTCAAGCTGAGAAAGTTGATGTGATTGCCGG
+
@@@ADBDDHFFFFGGGIICCHB9?:EHBFHGIII<GGF@HHED@FGHGECGGCH?CCDE@DCCCCCCCA@CCCCCCCCCC@CDDECCCBB
@7CJ
TGAACTTTGTCCCTCCCCATCCATCCTCCATGCCTGTCACTTCCTCCAGCTTCTTTGGAGCCGCATCACAATACTGGACCTCCCCCACGGGGGGAATCTAC
+
@@CFFFFFFHHHHIJJIJJJJIJIIJIIJJJJJJJIIIJJJJIJJJJIGIIJEHIJJJJJDIJIIJGHGHFFFFFFEEEEEDDDDDDDDDDDDDBBDDDDD
@7CK
CCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTGAGTTGCTAAGAGAGAAAACCAAAT
+
@@@FDFFFHHHHHIJIGEHIIIEIGHIIIEGEGGIJHGIHIDHGGGIIJGCH<FHIIIJGIGHIEFEDBBCBBCDCCC>CDDCCDCDCD?@BCCDDBDDBD
@7CL
CAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGAC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJIJIJJJIJIJJJJJJJIJJJJJJJJJJJJJJJJJJHHHHHFFFDDDDDDDDDEDDDDDDDDDDDDD
@7CM
CAAGGATATGCACAGACCACCCAGCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGC
+
@?;AD:DDFFD?DHGEFHGGGBHIGGIGIIEG>?CFEGHGHG@GEGA>F@BC=FCE4@GCCEGI=EHE9@;;?@:>@;>CC@CCAABBB9<@CCCBCBC@C
@7CN
CCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGT
+
@@?DD;DD:DA<D?F@3<8@)?CGC@G;?8DBF@F@BBBCF@FFFFIC;C;DA=3===B3;;7;;;>AC;?==A;>>;55(,(,+:@<8223+(:@:<<<:
@7CO
CTCAAAGCCGTGCACGAGCAGCTTGCAGCCCTCTCTCAGCCCCAGCAGAACAAACCAAAGAAAAAGGAGAAAGACAAGAAGGAAAAGAAAAAAGAAAAGC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJIGJJJJJJJJJJJIJJJHHHHFFFFFEEDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDD
@7CP
CAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCAC
+
CC@BDEFFFFFHBG@EDFHHGGHIIIIIIIIIIGIGHIFEFHBGEHIGGFFCHI;CHHEEDFDCCCEEDEDDDDDDCDDDDDDDDDDDDDDDCCA@DDDDD
@7CQ
CTCTTCACAACCTCTCCAAATACACAGACAAACTCCAGAAAGCAAGAATGCTACTCCCACCAAAAGCATAAAACGACCATCACCAGCTGAAAAGTCACAT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJGJJJJJJJJJJJIJJJJJJJJJJJIHHHHHHFFFDDDDDDDDDBDDDDDDDC>CDDCD
@7CR
CTGGAGACTCAGGTGGAGTCATGCTTATATGGAGCAAAACTACTGTAGAGCCCACACCTGGGAAAGGACCTAAAGGTGTATATCAAATCAGCAAACAAATC
+
CCCFFFFFHHHHHDHJGIIJJJIJJJJJJJJJIIJIJJJIJJJJJHHGIJJJJJJIIJJJJJJJJJJHGHHHFFFF@C@ACEDEEDDDDDDDDDDDDDDDD
@7CS
CCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGC
+
@@CDDDFAF?F?FBEHIIIIIGIHFHGGGGI@GGIIDDGGGCGHHI@FEHI<FEG@E;C@C>FEHCEE;A=A@CEBDCCCCBBBBB<?>>CCCC@CBB
@7CT
CGGCCCCAGCCAGATCCGTATCAGATCCTGGGCCCGACCAGCAGTCGCCTAGCCAACCCTGGAAGCGGGCAGATCCAGCTGTGGCAATTCCTCCTGGAGCT
+
@C@FFFFFDFHHGJIJJJHHIIGGGHIJJGIJIJIJIIJJJJJIGEHIHHHFFFFFCBCDDDDDDDDDDBBBDDDDDDDDCCACADCCDDDCDCCDDBBC8
@7CU
GTTGAATGTGACAGCACCTACACCTCAGCAGTTACAAGCCTTCAAAAATGAAGTAGGAGTACTCAGGAAAACACGACATGTGAATATCCTACTCTTCATGG
+
CCCFFFFFFBHHHJJJIJIGIJJJIJJJIJIEHJCHGCHIIJJJJJIJGEHJJFH>FGGGGIGIIIIIIJJIJGGFFCDDDEEEEDEEDEDDDDDDDEDDD
@7CV
GAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGAC
+
BB@FFFFFHHHHHJJJJJJJJJJJJJJJIJJJJJGIJJJIJJJJJJJJJJJJHHHHFFFFEEDEEEDDDDDDDDDDDBDDDDDDDDDDDDDDDCDEDDDDD
@7CW
CAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGC
+
?<8DDDDDDDDBBEB:AEA@CEFEB>EEEI:CDCDEII9B<@DDDDDDCBEEIECEEIDEIDDIIDDDD>@>?@A@AAAAAAA>AAAAA>AAAAAAADA<
@7CX
CTTAAATCAGAACAGGCCTTGATTAGAGACCAAGGATTTCGTGGTGATGGAGGATCAACCACAGGTTTGTCTGCTACCCCCCCTGCCTCATTACCTGGCTC
+
:=>;AA;A<C32ACB9+++3<3A=7?<7@=:1:57A3?:7?BA=05*0***=AA=AAB>BA<B>=A3=1.;?;;?@9>@@==90;9;8:;=?=:=??<8;3
@7CY
CCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGAT
+
=@@DA?DBAFHDFG?FF>DHEDCEH>CDHEH@GGG;DDGCGIIEGIEHIIBEC@FHIEGGGG>;@EHGIEH>BEEEE@C@AC;ACCA;@@CCCC69B@<B4
@7CZ
CGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCG
+
@@CFDDDDDAFDHEGGEGHGGHJIEGIGCEE6DAFHCF90;ABGHAHB88CEAE@CCEAA;>CCDCCBDCCCDCA>BB@B8AD>??BCCD@CCDDCDDCD5
@7D0
CCAGCTATTGGACCTTACTATGAAAACCATGGATACCAACCGGAAAACCCCTATCCCGCACAGCCCACTGTGGTCCCCACTGTCTACGAGGTGCATCCGGC
+
CCCFFFFFHHGHHJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJIJJJJJJJIJJJJJHHFFFDDDDDDDCDDDDDDDDDDDDDCDDDDDD<BCDEDDDDD
@7D1
GGAACCCAGAGATTTTGCATATGACTCAGAAGTGCCTAGCTGCCACTCCATTTATATGAGGCAAGAAGGCTTCCTGGCTCATCCCAGCAGAACAGAAGGCT
+
CCCFFFFFHGHHHJJJIIJJJJJIIIJJJJJIGGIJJJJJJGGJJJGIJHIIIIJJIGGIIJJJFIJJIIIIHHHEHFFFFFFEDEEEDDDDDDDDDDDDD
@7D2
GGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGT
+
CCCFFFFFFHGGGJJJJJJJJJJJJJJJJHIJJIJJJIIJJJJJJJJJJJJJIJJJJFGHHHHFFFEEDEADCDDDDDDDDCCCDDACD@BDDBDBDDDDD
@7D3
GCCTATGATCAGAAGCCACAAGTGGGAATGAGGCCCTCCAACCCCCCCACACCATCCAGCACGCCAGTGTCCCCACTGCATCATGCATCTCCAAACTCAAC
+
1??DDD;DDDDDFFFEGD??E@AFCDGGEFIFFEIIIIFIIEEGIAFEFECBBBCCC>>B5?'8?B?>@B,:A?9<@:@ABBAB>::3@@BBAAABAB>AB
@7D4
CCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCAT
+
CCCFFFFFHHHHHJJJIJJJJJJJJJJJJJJJHIJJIJJJJJJJJJJJJJJJJIJJIIJJJJJJHHFFFFDEEEEEFEFDDDDDDDDDDDDDDDDCDDDDE
@7D5
GGGCAGAGTCCTTCCAAGAAGCAGAAAAAAAAGAGAAAAACGTCAAGCAGTAAACATGATGTGTCAGCACACCATGATTTGAATATTGATCAATCACAGTG
+
>;:AA)?+2<?>===CAA=?3?=AC@BAA<A=47A>==B=A:==;A>AB=.>>AA>;;@?@.;666;>?====259559=(,,55;9(33+8=3(+3+++(
@7D6
AGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACC
+
CCCFFFFFHHHHHJJJJJIJJJIJJJJJJJJJJFHJIJJIIJJJJJJJJJJJHHHFFFFFEFEEEEEDDDDDDDDDDDDDDDDDDDDDDDDDDDEDDDDDD
@7D7
CTTCTGATGTTCAAGATCGCCTGTCAGCTCTTGAGTCACGAGTTCAGCAACAAGAAGATGAAATCACTGTGCTAAAGGCGGCTTTGGCTGATGTTTTGAGG
+
CCCFFFFFHHHHHJJJIGJJJJJJJJIJJJJJJJJHIJJJIJJIJJJJJJIJJJJIIIIIJJJJJIJIIJJHHHHHHFFFDDDDDCDCDDDDCDCDDBDBD
@7D8
CTGATCTTTCTGAACAATTGAAACAGAAACATGGTGAGATTAGTTTTCTAAATGAAGAAGTTAAATCTTTAAAGCAAGAGAAAGAACAAGTTTCATTG
+
CCCFFFFFHHHHHJJJJJJJJJJIJJJJJJJJJJEHGIIJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJIJHHHHHFFFFFDEEEEEED
@7D9
GCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACC
+
@@@FBDFFHHBBDFG@FHCEEGEIIIIIDGEGIGIIIIGFEEGIIHEIHEHHGFFBDDECEDDCCDDBC?@BDA?BBCDDEDBBCBDBBDDDCDDCCDDDB
@7DA
CTCAATGATATGGAGATGGTGATACAAGCTGGAGCCCTCACACCACTGGGTAACAATAGCCAGTTGTGGCTTTGTGGAATAGCCCATGAAGAGTAGGATAT
+
CCCFFFFFHHGHHHIGIHIIJJIJIJJJJJJJJJJIJJJJJJFGIIJJJJJJJJHHHIIJIHHHGIDGIHFHGD?DFEEEEEEEDDDDDCCCDCCCDCCDD
@7DB
CACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGAT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJIJJIJIJJGIHJIJJJGIJJJIIJJHHHHFFFEEDEDDDDDDDDDDEDDDDDDDDDDDDDDDCC
@7DC
GAAAAAAGAAAAGCACAAAAGGAAAGAGGAAGTGGAAGAGAATAAAAAAAGCAAAGCCAAGGAACCTCCTCCTAAAAAGACGAAGAAAAATAATAGCAGC
+
1?@FFFFDFHHHBBBDHHIGIIBHEHDGBC>D:?B?B@8BFEHCBEHH8E/=AACDB>DC?A>C;;?;A?55<CCCCC6<<59@7>CCCAA>@3>@>C@8
@7DD
CAGGTGGTCGTACAAACTGCATCAGGAGATATGCAAACATATCAGATCCGAACTACACCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATGACATCTCC
+
B@BFADFDHFHHHIJIIJJJJJJJEGHIJGIIJJJJJJJIJJJJJJIJJJJJIJJIJJJJJIJJHHHHHHFFFFFFEDEEDDDDD@CC<BDDCEDDCDCDD
@7DE
CGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCG
+
==?B=D@+A?D3C:32@@CE?DD?3B=?B)?1?3?DDCDADADCED6:<?DDAAEDAAA>AA3;AA?(8>>AAAA-59>;><<>>1(9+:>::>A>AAAA9
@7DF
ACAAGAGCCAGGAATGTATCGGGAAGGACCCACATACCAACGGCGAGGATCACTTCAGCTCTGGCAGTTTTTGGTAGCTCTTCTGGATGACCCTTCAAATT
+
=@@D1BDDHFDHFIAACE:AAG6FEGA;GGHGDDDGGIGGGIGEEHBBC@CAC;>@CCCCC@>@CCB9>CCBBBBCCA:>@CA@A>(::ACCB339:::>C
@7DG
CGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCG
+
CCCFFFFFHHHHGJJJJJJJEHGFHIJHIGHHIJJJJJJIJJJJJHHHFFFFEEEEDEEDDDDDDDDDDDDDDDDDDBBDDBDDDDDDDDDDDDDDDDDDD
@7DH
TGACAATGATGAGCAGTTTGTACCAGACTATCAGGCTGAAAGTTTGGCTTTTCATGGCCTGCCACTGAAAATCAAGAAAGAACCCCACAGTCCATGTTC
+
C@CFFFFFGHHHHIIJJJJCHGHIJJJJJIIJJJIJJJJJJIIIIIGIGJIJJJIJIJJJJIJJIJIIIJJJIJHHHHHFFFCFDDDDDBDDDCEDEDE
@7DI
GATTATTGGACTTGGCACTTTTGAGCGTGGAGTAGGATGCCTGGATTTTTCAAAAGCAGATTCAGGTGTTCATTTATGTGTTATTGATGACTCCAATGAGC
+
CCCFFFFFHHGHHJJJJJJJJJJIJJJIIJIJGHJJIJJJJJJJJJJJJJJJJJJJJJIFHIJJJJHGHHHHHFFEFFFEFEEEEDCEDEDDDDDDDDDDD
@7DJ
TGATAACTAAGCAGAATCAATTAATTTTGGAAATTTCAAAGCTAAAAGATTTACAGCAGTCTCTTGTAAATTCAAAGTCAGAAGAAATGACTCTTCAAATC
+
@@@DDFFFHFDDDEEHGIGGIGIIGGIIJJIJIJJJJJJGJJGIGHGHGHIJIIIGGHJBBHIJJGGHIGIIIIHIIGGEHFHHGHFDDFCFEDEDDCDDD
@7DK
GCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTCCTCCCC
+
@@@DDDFFGHGHHIJGIIIIGEFHIJJIIIHJJIICEHIJJJIJJGGIJIJJJICGHIJJJJGIJJHHHHFFFFFDECEDCDDDDDDDDDDDDDDDDDDDD
@7DL
CACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGC
+
CCCFFFFFHHHHHJJJJJJJJJIJJJJJJIJJJJJJIJIIIJJJJJJJJJJJJJJJJJJJJIJJIIIIHHHFFFFFEDEEDDDDDDDDDDDDDDDDDDDDD
@7DM
AAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCTCTCAAGGATATGCACAGACCACC
+
@@CFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHFFFFBFEEEEEEEDDDDDDDDDD3?CDDDDDDDDDDDEDDDCDDDDD
@7DN
ATAGCCAAGCTGCAGCGCAGCAGGGCTACAGGGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGG
+
:7>1<=A=<<+AC;;7)1)11111)?)?=0:)80>;9799A7:<A<.(5A@;.77655((;>?;(;?>?95=2,,,++2;8;83(+8;989983((3+(+
@7DO
GCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACT
+
@CCFFFFFHHHHHJJIJAHIICGIJJJJFHHIJJJIIJJJJJGGIJJJJJJGIFIJGIJJJJIJJHHHFFFFEDEDEEDECCDDDDCCDDDDDDDEDDDDC
@7DP
GTCCACTTGTGGAAGAGGAAGAGAAAGTGCCTGTGAGGCCCAAGGACCCTGAGGGGGTTCCTCCTCTCCTGGTCTCTCAACAGGCAAAACGGGAGGAGG
+
?@;ADBBDDHHADFEIIG?CDHEB;AF2C<9E?1?<:8)::B;FHIEDDHCHEHDBH/3;6;6;;5(-55:>5(:5:>@A9A@<(822<<009-)9829
@7DQ
GGGTTTTCTTTTCATCTTTAAGAATGCTATTCTCTGCTTCAAGTTGTGCAAATTTTTCTTGAAGATCATTCTCTTTTTCCTTCATCTGTTTTTCTAACAAT
+
@CCDDFFFHHHHHJJJJJJJJIGJJJJJIIIHIIJJJJJJJIJIHIGGIIJJJJJJJJJJJJJJIJJJJJGIEHJJJIEDHIIHHEHHHHFFFDFDECCEE
@7DR
CCTTTCTATCCCCAACCACCCCTCAACCCCTGTTTTCCCCTGCCTTCCTTGCAGAGGCCATGGAGGACGAGGAGAGACAGAAGAAGCTGGAGGCCGGCAA
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJGHHHHFFFFDDDDBDBDBCDDDDDDDDDDDDDDDDDDDDDD
@7DS
GAATTATGCAAAAGGTGGCTGGAGAGAGATATGTCTACAAGTTTGTGTGTGATCCAGAAGCCCTTTTCTCCATGGCCTTTCCAGATAATCAGCGTCCACTG
+
<;<;=9;@??88;48)2(=>8(3883<??@<<<:;?<<?<?8=?8.<)6.<>?;>??;;)6=;???>3):6)<)).6==??8=>8=;=;9=399<<;<===
@7DT
CGGGAAGGACCCACATACCAACGGCGAGGATCACTTCAGCTCTGGCAGTTTTTGGTAGCTCTTCTGGATGACCCTTCAAATTCTCATTTTATTGCCTGGAC
+
CCCFFFFFHGHHHJJJJJIJJJJIJJJJJJJJJJJJJJJJJJJGHHHFEFFFFCDACDCCDDDDDDDDDDDDDDDDDDDDDDDEDEEDEEEDDDCDDDDAD
@7DU
CTTACAGTTGGCAAGTCCAGGCACAGATGGAGTACAGGGACTTCAGACATTAACCATGACAAATTCAGGCAGTACTCAGCAAGGTACAACTATTCTTCAGT
+
CCCFFFFDHHFHHIJJIJJIJJJJJJJIGIJJFHGJIJJIIJIIJJJJHJIIIJJJJJJIJJIJIJJIJJJJHHHHHHFDFFFD6>CEEDDACDCFEDEDC
@7DV
CCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGT
+
CCCFFFFFHHHHHIGHJJJJJGIEIJJIIJIGHJJIJJJJJJJJJJIJJJJJIJJIIGHIIJJJJFFFDDEDCEDDDDDDDDDDDDDD@BBDDDBCDDDDC
@7DW
CAAGCTCCCCGGCGAGAAGCTGGGCCGCGTGGCGCACATCATCCAGTCACGGGAGCCCTCCCTGAAGAATTCCAACCCCGACGAGATTGAAATCGACTTTG
+
?+=BDBD?AC?DAE<ADD>B?9B@D?@<AAAD'39<;?AAAAAA>AAAA>800::8?=??=<=A?AAAAAAAA>>A>>????9>9>?A:>AAAA8>><>AA
@7DX
GGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATG
+
@@?DDFBDDHHHHGHIIHGFEHIIIIJEGHIJJIHEFDEGIHGIJGGIJJJJJIIHHFFFCCDDDDDCCBCCDCCDDCDD@BBDDDB?A<AC?CDDDCDCC
@7DY
CCTTCCGACCAGCAGATGAAGATCATCGAAATCAATTTGGGCAACGAGACCGATCCTCATCAGCTCCCAATGTGCATATAAACACAATAGAACCTGTCAAT
+
CCCFFFFFHHHHHJIIJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJHFFDEEEEEDDDDDDDDDDDCEDEEDDEEEDDDDDDDDDDDDDDDDDEE
@7DZ
GAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACT
+
@?<DDFDDFHGHGJIGIBHGGHIEHHIIJCHHIIJJJGGIJJIGHIIGEHIIGJIDGDCEDDHHGGCHEFFFFEEEEEDDDDDDDDDB?BDDBCCDDDDB
@7E0
GCGGGGCCCACTGTCCGCAGTGGGAGGCAGCGAGAACAGGGTATCACCCACCAATCACATAACCCGCGAGAGATTCTTGCTGTGGGCGGAAAGGTGGACT
+
((-51>(05=@?)):)(3</-;97(-3<(3-3''',=)..(.((-(-((,(3(,,,(((++(((+&)00&&0+((((+(++(+320(&&)5)((++(26:
@7E1
GCCATACCCCAGCAAAAGCAACCAGGAAGTTCTGGAGTTTGTCACCAGTGGAGGCCGGATGGACCCACCCAAGAACTGCCCTGGGCCTGTATACCGGATA
+
11:D;DD:=+A<3::?E9C?<AC@A?3:?9BD>DCII??DED>BB30?*?DDD(-5@8'--;AAA>=>@?==;9<?3>:>2:5(8<<2<4>4>B:9)0&)
@7E2
TATTTCTTCATGAAGACCTCACAGTAAAAATAGGTGATTTTGGTCTAGCTACAGAGAAATCTCGATGGAGTGGGTCCCATCAGTTTGAACAGTTGTCTGG
+
CCCFFFFFHHHHHJJJJJJJJJIJJJJJJJJJJJCGHIIJJJJGIIJJIJJJJJJJJJJJJJJJJJJJHIEHIJHHHHFFFFFEEEEEEEDDCDDDDDDD
@7E3
CCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTTATGGGCAGGAGT
+
@@@DDDDEHHDHHCHDBHIIIFDGG7CFHIIIDEGIIIGIIFGIB@;BDCF@FFFGEIHGIHFFDDFDDCDDBBB:AC@ACCBD590?CCCAC@DABB883
@7E4
CAGATAATCAGCGTCCACTGCTGAAGACAGACATGGAACGTCACATCAACGAGGAGGACACAGTGCCTCTTTCTCACTTTGATGAGAGCATGGCCTACATG
+
CCCFFFFDDHHBHIJIJJIJIIIJJJJJJJIJIJJJHGHIHHIIJIIGIIJJIIIIIGHHFHFFCCEFCCEEDEDECCDDDCCDEDCDDDCDDDDDDCD@@
@7E5
CTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCT
+
CCCFFFFFHHHHHJJJJJJJJIJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHHHFFDDDDDDEEEDDEDEDDDDCDDCDDDDD
@7E6
CAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGC
+
CCCFFFFFHHHHHJJJIJJFGGHIHHIJJJFHGJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJIHHHFEDFDDEDDDDDDEDDDDDDCDDDDDDDDEDD
@7E7
ACCAGCCCAGCCTAGGATATGGACAGAGTAACGACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCT
+
CCCFFFFFHHHHHJJIJIJIJIIIJIIJFHII)1CGGFGHGIIJJJJIFHGGIJGGFEHIIHHHGFFFFFEEDDDADCDCDCDCDDDDCDDDDDDDDDDDD
@7E8
TGAAGAGGTGGCCCGACGTTGGGGCATTCAGAAAAACAGGCCAGCTATGAACTATGATAAACTTAGCCGTTCACTCCGCTATTACTATGAGAAAGGAATT
+
???DADB32<AD?C?1<?:C@?:?DDA?DEBDDBB2A=CIII=AA@ACDDD;?=;??3?;A;A@A@@A?;8?3:5>????30>:A>>BAA>>>>A<?>>A
@7E9
CCAGATAGCAGCTACCCCATGGACCACAGATTTCGCCGCCAGCTTTCTGAACCCTGTAACTCCTTTCCTCCTTTGCCGACGATGCCAAGGGAAGGACGTCC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJGIJJJJJJJJJJJJJJJJJJJJJJJHHHHHHHFFFFFFEEEEEEDDDDDDDDDDDDDDDDDDDDDDDDDDD
@7EA
TATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTC
+
@@@=ADDDHFFHHIIIIAEFGHGGFGHGGIHHGIIIIIGHGHIIIIGCGDAHIIIIIIIIIGIIIEIH9CHFDEECD;ACCCCBBBBB?BBBCCCCCC9@>
@7EB
CCCTGGGTCCTGGAGAAACCCTAGTACCTGGGGATACGGAGAGCAGTGTGATTCCCTGTGGAGGCACAGTTGCGGCAGCTGCCCTAGAAAAGAGAAACTAT
+
@@@DDDDADFHGDIIJGHIIIEGHHEIIHGIIGGAGHIJJJIJIIGFFBCHGGHIGIIAEHCEFHFEEDDECCCDBB@@:>?ADDD?<ACCC8??CCCCDC
@7EC
ATTCATTTTCCCTCCATTATCATAAAATCAGATCGATATTTATGTGCCCCAAACAAAACTTTAAGAGCAGTTACATTCTGTCCCAGTAGCCCTTGTTTCCT
+
+11ADAD>CFHAHGHGEHIIEIGGGGIEGEGCEFH?3?DDFHFC9BEGGHIIIIIIEEHIHIIGCHGFD97@ACEHHCCCEFDCD;(6>;;@?=CC@5>CC
@7ED
CAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGC
+
CCCFFFFFGHHHHJJJJJJJJJJJJJJJJJJJJJJJJJABHIJJJJIIJ@EFHHHHHHFFFFFFDDDEDDDDCDDEDDDDDDDDDDDDDDDDDDDDDDDD
@7EE
TACCTATAGCCAAGCTGCAGCGCAGCAGGGCTGCAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCT
+
C@CFFFFFFFHHHHJEJJIJJIHGIJJJHIJJ08BGDFGGIJJIIJJJJJHFHHFFFFEEEEEDDDDDDEDDCCDDDDDDDDDDDDDDEDDDCB?ABDDDD
@7EF
AAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTAC
+
@@@FFFFFHHHGHJGIIIJJJJJJJJJJJJIJJGJJJJIIIJJJJGGIJJJJJHHHHFFFFDEEEDDDDDDDDCDDDDACDDEDDDDEDDEDDDDDDDCCD
@7EG
TTCTTTTGAAAATATGACTGTTGGAGAAGAAAGTAAGCAAGAACAGTTGATTTTGGATCACTTACCATCTGTAACAAAGGAATCATCACTTAGAGCAACTC
+
B@CFFFFFHHHHHJJJJJJJIIJJIJJJJJJJJEGIJJJJIJJGJIIIIHHIJJJJJJIJIJIIJJIJJJJIJJIJHHHHHFFFFFDEDEEEDCDDDDDDD
@7EH
CAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTC
+
CCCFFFFFHHHGGIJCGICEHIJGGGCGHGIJJIJJJJJJJJJJJJIJIJIJGIJJJIIJJJJJJHEHFFFFFDEEEEECCDDDDCDCCDDDDEDDDDDC
@7EI
CTCGAGAGTGTCGTAGAAAGAAGAAAGAATATGTGAAATGTTTAGAAAACAGAGTGGCAGTGCTTGAAAATCAAAACAAGACATTGATTGAGGAGCTAAA
+
CCCFDFFFDFFHHGHIJIIJJIJJIIJJJJCEIDGIGGFFIIICHIJJHBC@@F=EHCHG8BAHHBHHIGC:AEFF;?B>@6;AC>;@C:-;955<ACCC
@7EJ
CACACGACACCTACGACAATGTAGCTCACTTCCACTATGACATATCAAGAGGGGGTCTATATGCCCTAACCAGCGGCTTCATACGCTGATTTCCCCTATTC
+
(0(28;/@83()).-(2((...9).8:3)..))01)))))993.)).9)93('--,,(.:.-4(-(((((,(,6'&)587(4((()(&&+(+(+22(++8/
@7EK
TCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATG
+
=@;D?DDDA<FFHGGIIGGIGDH@HAHCHBGGGEAAF9F:@@G@B<B8DC8=FGC7@EG;=D4.77@3=C@E>?@@DC=C;@5(((5=A<@;@B5929@CC
@7EL
CAAAATAAAACTCTAATAGAAGAGTTAAAAACTTTGAAGGATCTTTATTCCAATAAAAGTGTTTGATTCCTAAGAAAGAAAATATTTTTGTGGACATGCAT
+
CCCFFFFFHHHHHJJIJJJJJJIJJJJJJJJIJJJJJJJJIJJJJJJJJJJJIJJJJJJFHHIIIJJJJJJJJJJJIJJJHHGHHGGFFFFEDEDEDDDDE
@7EM
CGGGACTCGAGTGATGATTGGGAGATTCCTGATGGGCAGATTACAGTGGGACAAAGAATTGGATCTGGATCATTTGGAACAGTCTACAAGGGAAAGTGGC
+
@@@BB?B?CFDBD@EFHIICGGIIEEFHHCD9CGDGIC:;DFGIIIBGCGFBFGGGGHIEC@EADHHHFA=;7;B;;@CCCCCCCCCCCCBBBBBB5>A7
@7EN
CTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJIJIJJIHIJIJJHHHHHFDFFFFEEEEDEDDDDDDDDDDDDDDDDDDDDDDDD
@7EO
CAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCT
+
CCCFFFFFHHHHHIJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJHHHHFFFFEEEEEEEDEEDEDDDDDDDDDDCDDDDDDD
@7EP
AAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCAC
+
@@@DADFFHDDHHIHGIGGGGGEADFHGGBFGHGIIIIDIIGGGHGGGAE>GHEEDCDE?A@ACCACCCB@BDB??BBDBBCCCCCB3>:A3>:@<?<ACB
@7EQ
TACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJFHIJJJJJJJJJJJJJJJJJDHIJJJJJGIJJJJHHHHFFFFFEDDECDDDDDDDDDDDDDDDDDDDDD
@7ER
ATCAGTAGTAGTACTATTTAATTATGAGGAGAGAACTCAGCGACACTACCTGGGCCATACAGACTGTGTGAAATGCCTTGCTATACATCCTGACAAAATT
+
CCCFFFFFFHHHHJJJJJJJJJJJJJJJJJJJJJIJJJIJJJJJIJJJJJJJJJIJJJJJJJJJJHFHEHHFFFFFFEEEEEEEEDEEDDDDDDDDDDDD
@7ES
CTATGGGCAACCGAGCAGCTATGGACAGCAGAGGAGCTATGGACAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGAGCCT
+
?=++=+=BDC;DDEIIAAF9??::1111110::)000)0/??*8=8=BD6)=)7()77=;667?(;((.(5;,,=(:A,(,5,>>?;;;<81<AA>((+((
@7ET
CAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCC
+
@CCFFFFDHHGDHJIIJIIEHIJJJGHIJJIJJJJFHHIGIJGDHGJIEHIJJJJJJJJGHGGHHFFFFDDEDEEECCDDBDDDDDCDDDDDDDDDDDDD
@7EU
ACCAGCTATTGGACCTTACTATGAAAACCATGGATACCAACCGGAAAACCCCTATCCCGCACAGCCCACTGTGGTCCCCACTGTCTACGAGGTGCATCCGG
+
@@@DDDDADBFHHIGGCHIICHEHGHGIGGGEFGGIGIIIHHG8GBHHGHIGIIECGIIGFBEE?AAB;=@->CCCABD?B?CACDEC?959)8@CCCDBB
@7EV
CGGATCCAGAAACAAGCCCACCAGCTTGTGGAACCCAACGTACGGCTCCTGGTTTACAGAGAAACCCACCAAAAAGAATAATCCTATAGCAAAGAAGGAGC
+
CCCFFFFFHHHHGJJJJJIJJJJJJJJJHGIIJJJJJJJJHIJIJIIJJIJIGHHHHHFFFFFEEEDDDDDDDDDDDDDDDEDDDDDDEDDDDDDDDDCDD
@7EW
GAAGAGGTGGCCCGACGTTGGGGCATTCAGAAAAACAGGCCAGCTATGAACTATGATAAACTTAGCCGTTCACTCCGCTATTACTATGAGAAAGGAATTAT
+
<@1BDDADH@;BFDEBGFHIIDHG:FF>FE@<FAD6==FGAGE=GGHE>EFFDH:@CCC>;ACC@@>@>@CCCCCCB??>BC@CACDC>>@CCCBBCC>CD
@7EX
CAAAGCTCATGATGGCAGTGTGTTCACACTTTGTCAGATGAGAAATGGGATGTTATTAACTGGAGGAGGGAAAGACAGAAAAATAATTCTGTGGGATCATG
+
CCCFFFFFHHHHHJIJIJHGFHFHJJIBHIJJJFGIIJGIJIHIIJGGIHGGIIGIEIIJIJJBGH@FHHHHFEDEFFEEEEDBDDEEDDDDCDDDCBDDC
@7EY
GCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACA
+
CCCFFFFFGHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHHFFFFEEEEEEDDDDDEDDDDDDDDDDDDDDDDDDDDD>BDDD
@7EZ
CCTTACAGTTGGCAAGTCCAGGCACAGATGGAGTACAGGGACTTCAGACATTAACCATGACAAATTCAGGCAGTACTCAGCAAGGTACAACTATTCTTC
+
@@CFFFFFHHHGHIJJFIIJEIIIGGGGGGGHI?EGCCHBGIGHIJGGIIJJIJJJIIIJIGIJGHGIIHGGHEHHFFFFFFFCB6@CCDDCCCEEEED
@7F0
ACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGC
+
@@CFFFFFFHHFFHJJIIIHIGJJJIIIIGFGGIJJJJJJJIJJJJJJHGBGHIIJGGIIJJIIJGIHHGHGFFFFFFEEDEEDDDDDDDDDBDDDDDCDD
@7F1
GCCAGGTGTCCGGAATGCCCAACGACCCAAGCCCCCTGCAAGTGGCTGTGAAGACGCTGCCTGAAGTGTGCTCTGAACAGGACGAACTGGATTTCCTCATG
+
@@;BD?2:2<DFFIBG@::3<AF;B?:?:??DGEFAFFI;)=87=FC5(.77)..9/98/.5;;>A(5(5@;>5(::,>9??+009&++3>@AA>A3>BB>
@7F2
TGGCAGTGCGGCCAGCCAAAGCTTTCCCCCTCCTCTGATGATTAAACAGGAACCCAGAGATTTTGCATATGACTCAGAAGTGCCTAGCTGCCACTCCATTT
+
C@CFFFDFHHHHFIIIJJJIJJJJIJJJJIGIJJJIJHIJJGGIIIJJIJBGIIJHHHHFFFFFFEEDDCEEDCDDDDDD@@CDDDDDDACBACDDDCDEE
@7F3
GAAGAGCCTAAACCTCTGCAAGGAAGATTAGTAAGCACCTGTATTCCAAAATCCAAGGCCGGTTGGGATGCCAAGATGACCTGACAACAGCAGCGTGCGGC
+
(;(((.)():;):))))294;)(3)((..)).)))).:?>1.>)):>)<)(.)).))<(7''''--3(8=(6((,9((-9-3((,(,3(3((2(&()&&&0
@7F4
CAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCACCCCAGCCTAGGATATGGACAGAGTAACTAC
+
;=@DBAD@AFFDHIGBFBECEH3C?FCHG@DG>FH@GIGGBFCAGGFHFG@=FFCHIIFFE:@?@CCCBBBBBB?BBBC@?CC:>AACA>>?AC:>@CDCC
@7F5
GAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGAT
+
?8=DDDBB;FBFFGIH>EGGI<AHADGHGGGFHDB<BDGHHEGDGIIIIIEHGIGGFHEB>ACCBBBB9>A>A@@@CCCCCBBBBBBBB?B?AACC>CBC
@7F6
GATGCAGAAGGTCCACGTTTCCAGAATAAAGCAGCCAAGGTTGGGGGACCCAACGAGCGTCTGAAGGGTTAGAGAGAAACAAAGCAAAAGGAATAGTCCT
+
0-(2(2))<;?>??4;(((.<).<))))2):>))(1():():73(<'';????((('9''7;;((,7'((,((((2(((5((2(38(2((((++((+((+
@7F7
GTGAACTTTGTCCCTCCCCATCCATCCTCCATGCCTGTCACTTCCTCCAGCTTCTTTGGAGCCGCATCACAATACTGGACCTCCCCCACGGGGGGAATCT
+
@?@FFFDEHDCFDBHEFHGDHGIGBBHBFH@CEGCHHCDBGBF@BHIGF<BFDCHDH@B==BF@EBHBHH@DF@@;;>6>>C@;;;;:?BB@95<&0<CC
@7F8
ATCCTTTCCTGTATATTAAACCACGTTTTTGGCTTTTTCCTTCCTGTCCTTCCCCATCTGGCGATGGTGAGGATGGGTTTTTTCTCTTCCATGTTATCATC
+
CCCFFFFFHHDDFGIIIIJGGHJJJHGJGHGGHIIJJIJFJJJIIGDGHIJJJJIJGHIJJJIBGHG?ACBFDEEDC;?BDDDDDCDDDDDEDEEEECDDD
@7F9
CGTGGATTTCAAACAGTCCAGGCTCTCCGAGGACGGGCTGCATAGGGAAGGGAAGCCCATCAACCTCTCTCATCGGGAAGACCTGGCTTACATGAACCAC
+
@@;DDBDACFFFDGHIIIIIIFIGGHGIEEFAHGIIIIIGGICHEGGACECHHEEEECCCCCCCBCCCCCCCECCBB@BBBCCCCBBCBCCCDCCCCBBB
@7FA
CAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCC
+
@<@@DFFFHHGFHJJGGFHGIIGGGHHAHGGIEHJEEGGIIHIGGHBIJI9@CEGGEHGC3==ACDBBBAEDDCB?>25>>55@>35,:?AACA3>?B<<B
@7FB
CTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAA
+
@@@FDFDAFHBHD<FGIGFHDEC@FCGAFBAEGGGIGGH@FGHIHI>AFDEEEIC==C@@@DDEBD<BEBECAA>@AA??ABDB>C>CCD@CD>CACDCB
@7FC
CTGCTGAAGACAGACATGGAACGTCACATCAACGAGGAGGACACAGTGCCTCTTTCTCACTTTGATGAGAGCATGGCCTACATGCCGGAAGGGGGCTGCTG
+
@@?DDF;DFHDFFIIIFGGEEGBGGGBCHIIGHAG6@FHG?BFGGIDEF@F;FHHGGICEEGHC>CEACEDEFFACBECCCCCC>C?/;B>B9@<<<BBCC
@7FD
GCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCC
+
@@CFFFFFHGDHDIGIJDIHGIIIIJJJCHHEHJJJIIIIDGJJHGIJIJJIIIJIIJGCCGIJGIGCFGHHFFFDDEDDCCACDDCDDDDDDD<ABDCD
@7FE
CAAGAGTACATCCAAGCCATTATGATGATGGAGGAATCTGTTCAACATGTTGTCATGACAGCCATTCAAGAGCTGATGAGTAAAGAATCTCCTGTCTCTGC
+
CCCFFFEFGHHHHJJJJJJJJJJJIJJJJJJJJJIJIJJGIIJJJJJJJHIJIJJJJJJJJJIJGHHIIGEHGGIEGHHGAEHFFFFFFEEEECCDDDCDD
@7FF
CAGAGATTTTGCATATGACTCAGAAGTGCCTAGCTGCCACTCCATTTATATGAGGCAAGAAGGCTTCCTGGCTCATCCCAGCAGAACAGAAGGCTGTATGT
+
CCCFFFFFHHHHHJJJIJIHIIIIJIFHJIJJIJJIJJJJGJJJJJJIIJJJIJJJJJJJJJJJJJGDHIJJJJJHHHHHEFFF@CEECDDDDBDDBDEEC
@7FG
TGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGC
+
B@CDDFFFHHHHHJJJJJJJJJIIJJJIJHHHIJJJJJJJJJJJIIGIJJJJJJJJIGIIIIIJJJJJGIGHHGHDFFFFECEEEDDDDDDDDDDDDDDDD
@7FH
CACAAGGCTTTAAGCAGGAGTACCACGACCCAGTGTATGAACACAACACCATGGTTGGCAGTGCGGCCAGCCAAAGCTTTCCCCCTCCTCTGATGATTAA
+
@CCFFFFDHFDHHGGGHIAGAFHIGGIGIIIIIBDHIIIIIIIGIGIIIGIIHG@DEGHHGAEFFDCDBDDBBCDDDDDDDDCCBDDDDDDDDEDEDDCD
@7FI
ATCCATTCCATTTTGTGAATTGTGACATAATAATAGCAGTGGAAAAAGTATTTGCTTAAAATTGTGAGCGAATTAGCAATAACATACATGAGATAACTCA
+
CCCFFFFFHGHHHJJGIJJJJJHJJJJJJJJJJJJJJJJIJJJJJJJJIIJJJIJJJJJJJJJIFIJJJJJJJJJJJHHHGHHFFFFFFDCEEDEDDDDD
@7FJ
GTCAGAGTGTGGGATTCTGTTACTCTATCCACACTGCAGATTATTGGACTTGGCACTTTTGAGCGTGGAGTAGGATGCCTGGATTTTTCAAAAGCAGATTC
+
@@CFFFFDFFFFHJGHIIIJJJJJJJJJIJJJIJJJEHIGHIGGHIGIJJJIGHJIIJJJGFEHHGHGEE=CHD>@DFEEEDEEDDDDACCDDDDCDDDDC
@7FK
GCTAAACAGAGAGCTGGAAGAAATGAGGGTTACCTATGGGACTGAAGGACTGCAGCAGTTACAAGAATTTGAAGCTGCCATTAAACAAAGAGATGGCATT
+
CCCFFFFFDHHGHIIIJIIIIIJJHGGIFEGHDDGGHICHGIJIGIJGIIIGGIGAGCDHIGIGEHGAHHEHEEDDFFFCEEEEECCBDCCA?CCCCCDD
@7FL
ACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGG
+
@@@FFADDHFHHHICHIIIIIIII@HGIIIIGECG?FHIIIIIIIIIIEHGHIICHGGGEGHGGDAEHEEEECEFDEDCEEEDDDDCCCDDCCDCBDDDD
@7FM
CAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCAC
+
CCCFFFFFHHHHHJHHJJJJJJJJJJJJJJIJJJJJJJJJJIJJJJJJJJJJJJJIJHHHFFFFEDEEEEDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDD
@7FN
AGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJIIJJJJJJJJJJJJJJJJJJJJJJJJHHHHHHFFFFFFEDEEEDDDDDDDDDDDDDDDDDDDD
@7FO
CCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTC
+
C@@FFFFFHHHGHJGGGHJIJJGIIJJIJIJIJJIJIJJJGIJGIJIIIGGIIIJJIJHHEHHEEFFFFFFCEDCCDDDBDDDBBBDDDD@CDB?BDAADD
@7FP
CCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCT
+
@@@FFFFFGHHHFGIIJIIGIGHGIIJJICFGGIEGGIIG>DHIGIJEHGIIIIJJIJJJIJJJJHHHHFEFFFFDDDDBBDDDDDDDDDDEDCACCCCCC
@7FQ
CTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATG
+
@C@BD;BDHHFDBHIJGGGHB:EEFC<DC>FGID@?FHIEHHGD:FHHHDHEEE@CBD@>A@CEDDDC@C3?BDDBDDDCDDDDCCC8?C@DBDD9A:AA@
@7FR
GGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTAT
+
CCCFFFFFHHHHHJJJJIJJJJJJIIJJJJJJJJJJIJIJJJJJJJJJJJJJIJJJJIJJJJIJJJJJHHHHHFFFFFDDDDDDDDDDCDDEDDDDDDDDD
@7FS
TGCAGTTCAGAGGTAAATGGTTGCAGTTTTGTGATGAGAACAGGAAAGCCTACAAATTTATTAAGGGAAGAAGAATTTGGTGTTGATGATTCTTATTCTG
+
CCCFFFFFHHHGHGIJJJJJFHIJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJIIIHHHHHHF?BDBDEEDDDEDDDCDEEFE
@7FT
GTTTTGGCTGTGGAGTTTCACCCAACAGATGCAAATACCATAATTACATGCGGTAAATCTCATATTTTCTTCTGGACCTGGAGCGGCAATTCACTAACA
+
:1:=:BDD?F<DF<C+A?<FHHBC;FFGEE>FGA9??9DDADGBDFD?0B*?AF:;7==;CECAEECE>CE3=AADB?@B@AB@:?8;'9:ABB3434>
@7FU
CCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATCTCAGCTATACCCAGGCTC
+
???DD;BB?:;AD9EE@>4CF43<F9;?3C):???B3)*?*99D(9?BB=>;8774ADCC9ACA3?C>3???@>==;;:>;>>>>5>>A>3;:5<?8<8
@7FV
GAAAGTGCCTGTGAGGCCCAAGGACCCTGAGGGGGTTCCTCCTCTCCTGGTCTCTCAACAGGCAAAACGGGAGGAGGAGCGCAGCCCAGCTGCCCCACCAC
+
?@?DDBDDFHF:CE?FEEHGIIIIFIIIFEHGHIG;AFGGGIGI<EGHIECCAHEED@BDCCCCBBC=BBBBB@BBB@<?5<9<@??BBB:@CBB?<9>??
@7FW
CAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTG
+
??@BDDD?BDB<F@DC?ACFFBHFEHI9F<???CFBB?FFD:;@=8@FHII=D???=;?;>CA;A>>@@;--5555:>:>@::@D@ADC@@BCB?CAC:AC
@7FX
AAGGAATTATGCAAAAGGTGGCTGGAGAGAGATATGTCTACAAGTTTGTGTGTGATCCAGAAGCCCTTTTCTCCATGGCCTTTCCAGATAATCAGCGTCC
+
CCCFFFFFHHHHHJJJJJCGGIJJJIJIJGIIJJJJJJJJJJJJIIJJFHFHHJJJJJJJJIJJJJJJJHHHHHHFFFFFFEEEEEEDDDDDDDDDDDDD
@7FY
CCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGC
+
@@@DDFFFFHHGHGIIJJGIJJJJJGEIJIFIIGGIJIJIGIGHGIDH@G>GGHB@FIGHGEIIJHHECEEDFFFFEECCEEEDDDDCCCCDBCCC>@BB
@7FZ
AAAACCGAGTTGCAGTCCTGGAAAATCAAAATAAAACTCTAATAGAAGAGTTAAAAACTTTGAAGGATCTTTATTCCAATAAAAGTGTTTGATTCCTA
+
CCCFFFFFHHHHHJJHJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHHHHHHFFFFFFE;ACEEDDDDFFDD
@7G0
CTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCT
+
@@@FDDBDDFAFFDEIGIIIIEHICHBCGABBC??DFF@@GH?DFGIIGCH@7CFHCHHGIIHHH@>2;@C9;>;;;>5@CC>>CBBDD<?<?>@ACCDD>
@7G1
GCCAATTACCATGTTCATTCCTTTCGATGTTGACAACTATGATGACATCAGAACGGAACTGCCTCCTGAGAAGCTCAAACTGGAGTGGGCATATGGTTATC
+
CCCFFFFFHGGHHJJIJIHGGIJJHIGJIIIGEHGIIJJJIJIJJJJJJJIJIIJJJJIJGEIJJJJJIGGIIHHHHHFEFFFBACCDDDDDCDEDDCDCA
@7G2
GTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCAATGGGCAGCAGCCTCCCACTAGTTAC
+
711AAAA@+2,+7?2<+AA<@AB++<A3AA>:4AA67=3?BA=?7=;=A5=;877>7==.>>>>>=>A>>>7>@((.;>;;;;=====(9;88;9;338=?
@7G3
CTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCT
+
@@@DDD:BDFAAAFEEFFF;E@9CEGFGIE@DF9?D@DFGDD9BFFIIIFFFE>AFEEFC>EFECDBDB@@?B@=?ABBDEBBBAB@B<BB??BB>ABB@@
@7G4
CATAAATGAAAGCTTTGAAGGTGAAGATGGCGATGTGATTTGTTTGAATTCAGATGACATTATGCCAGTTGCTTTAATGGAAACGAAGAACCGAG
+
@?@ABDFDHGFFDHIEHHIEGCF@FE9FBC@FGII@GEGGBFGGAFEEEHGGI@D?9=FGHCGIH>AFHE>@HGIEEEHGDFFFFCC?BCCBCB@
@7G5
CGACCATCACCAGCTGAAAAGTCACATAATTCTTGGGAAAATTCAGATGATAGCCGTAATAAATTGTCGAAAATACCTTCAACACCCAAATTAATACCAA
+
CCCFFFFFHHHHHJJJJJJJJHIJJJJJIJJJJJJJJJJJJJJIJJIIJJIJJIJIHIJJJJJJJJIIJIHHFFFFFFEEEEEEDDDDDDDDDDEEDDDD
@7G6
GAAGAGCTTCATTTGCAAAGAATAAATCCAACTACAGTGAAAATGAAAAGTTCTGTCTTTGATGAAGACAAAACTTTTGTAGCAGAAACATTGGAAATGGG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJIJJJJJJJJIJJJJJJJJJJJJGHJJJJJJJJJJJJJJJJIJJJJIJJJJJHHHHHHFFFFFFEEEEEEDDDD
@7G7
ATCGTGGAGTACGCCAAATACGGCTCCCTGCGGGGCTTCCTCCGCGAGAGCCGCAAAGTGGGGCCTGGCTACCTGGGCAGTGGAGGCAGCCGCAACTCC
+
=?@:=DD=D2<:<)88@FC+A;CAA:@DG<0?@FEED?BBA@;=6>;88)(+0057@AAA>@5<BBBB<3:9?:A281?@3>A38?702<?B-09&3@A
@7G8
ATGCTTTAAGGTCATATTCAAATATTACAGTTAATGAAGATCAGATAAAGTTAATGAATGTGGCAATAAATGAACTGAATATAAAATTGCAAGATACTAAC
+
C@CFFFFBHHGBFFHGGIEIIJIHHIGIJIDHGGHEHIHIJGGGIGGIGHHGGHGIGEEHBGIGGEGIIJJJJGEHGHGIEEHIGHIHEEHFHEECDDCEA
@7G9
CACTAACTAACGTGAAAGCCTTACAGAAATCTCCAGGACCTCAGCGAGAAAGGAAGTCATCTTCATCCTCAGAAGACAGGAATCGAATGAAAACACTTGGT
+
@CCFFFFFHHHHFHIJHGJJJIJJJJJJIJIJJJIIJJJJJJJIJJJJJIJIIIJJJJJJJJJIHHHHHHHFFFFFEEEDDDDDDDDDDDDDDDBBDDDD@
@7GA
CTGAAAATGAGTTTTCTTTAAGGCCAATTGACAGCAACACGTTTGAAATGAATGGCAAAGCTCTCCTGCTGCTGACCAAAGAGGACTTTCGCTATCGATCT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJIIJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJHHHHHFFFFEEDEDDDDDDDDDDDDDDDD
@7GB
ATTGAAAAGAGAAATAAGGTTAATGAAAAACAGAGAAGCTGCTCGAGAGTGTCGCAGAAAGAAGAAAGAATATGTGAAATGCCTGGAAAACCGAGTTGC
+
CCCFFFFFGHHHHJJJJJJIIIJJJJJJJJJJJIJJJJJJJJJJJIIIIBFFHHIJGIJJIIHGHHFFFFFEEECEEEEDDDDDDDDDDDDDDBDBBDD
@7GC
CTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAA
+
@@@FFFFFGDDDFIFHHGIJIIIIIIEGGGIEIHDG@@DFIGIIICGGJIIJCGCAAGFHGIIHEBDDDEDCA>;ACDDDD@DBCDDCAD>CC>C@C:@?
@7GD
CTGTCTCAATTGCAGGAAAAGAAACTCTTTCATCTGCTGCTAAAAGTGGTACAGAAAAAAAGAAAGAAAAACCACAAGGACAGAGAGAAAAAAAAGAGGA
+
=??ABDDEDHHHHDFGDGHI@GF@FEHGIAHIJIDHI>GGEGHIJG:DH?BFEGEGIGGAEGCHE=AHEFFB;=1?ABBBAC8A?CBBCDDDDDD<@<?A
@7GE
CCAACGGCGAGGATCACTTCAGCTCTGGCAGTTTTTGGTAGCTCTTCTGGATGACCCTTCAAATTCTCATTTTATTGCCTGGACTGGTCGAGGCATGGAAT
+
@@CDDDDDFAFFFHIEHDGEGIIIIGGEA;B??=CFIE;@@EHDHI@?EEA?>>CDDDCEEEEDDDDCC@ADDDDDCCDDDB9?><A:>5095<<@??>@:
@7GF
GAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGAC
+
@CCDDFFB>DFHDFFBGHIGHDHHGGGFHIIIHI?DGHIGCF@GDACHAGEEHFHGFBBFEDCCC@@CDDDD8?BDBBB@<A??CDA:@A>CC4:@CCC?B
@7GG
CCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGCAGCTATGGTCAACAAAGCAGCTATGG
+
7++A107AAB,2+?C<,+3+?<=@>>=42A3*1:1:77AA)00:AA32)07=;0A/::3=BA).>7>=1.;;5=((.(-5;;((,5;??:=(9>;<3:;(5
@7GH
CCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGT
+
;51=@?8<42.;)6@)8;<2(((.9<>((.<99>7<=??????<86>?>?3;;6.))63=))8;6188==,,9(6(76(;;5(36;/826:/22666826+
@7GI
CACGTATGAGTCGGAGGAAGAGGACAAGTGCAAGCCTATGTCCTATGAGGAGAAGCGGCAGCTCAGCTTGGACATCAACAAGCTCCCCGGCGAGAAGCTGG
+
@BCFDFFFHHHHHJIIIHJJIJJJJJJJHIIJJIJIJJJJHIIJJJJJJJIJJJJGIJHDDDCECDDDDDDCDDDDDDDDDDDACDDDBDBB@BDDDCDDD
@7GJ
ACACGACAGGGGTAACCTGGGGCTGGAGGGAAGCTGTACTGTCCCACCTAACGTTGCAACTGGGAGACTTCCGGGGGCCTCACTGCTCCTAGAGCCCTCTT
+
=@@?D::DFDAF@C@??CAGBHGGG>3BFIICH?BGBB<CGCADHIEA@CE??EDBBDCCCCCC?;9?>>@>=?@@>9BB<:?@>C@CACC@CA@8?CBC@
@7GK
CAAAAGGAGCAGAAATAAAGACAACAAATGAAGTTGTTTTGGCTGTGGAGTTTCACCCAACAGATGCAAATACCATAATTACATGCGGTAAATCTCATATT
+
@@BFFFFFHHHHFIGGGIJJIGJFGCIIIIAEHEBFI@GGGEEHIBFF>DBCFGHEHIIC@EEEACEHHACDDCCCFECCDCCEDCDB8??C@AACD;CDA
@7GL
AGGACGTCCTATGTACCAACGCCAGATGTCTGAGCCAAACATCCCCTTCCCACCACAAGGCTTTAAGCAGGAGTACCACGACCCAGTGTATGAACACAAC
+
CCCFFFFFHHHHHIJJJJJJJJJJJJJJIJJJJJIJJJJJJJJJJJJJJJJJJJJJJJHHHHFFFFFFDEDDDCCDDDDDDDDDDDACCDEEDEDDDDDD
@7GM
CAGGGACTTCAGACATTAACCATGACAAATTCAGGCAGTACTCAGCAAGGTACAACTATTCTTCAGTATGCACAGACCTCTGATGGACAGCAGATACTTGT
+
@@?DDDDDH<D?<FHIGEEHB?FHIGC@HCHA><BFCGD?1C9?@D>FDE9B@BD@EHGI4BGHGG@@FH@C@=7.=;CCEH@@BD@C@1?C??@CCCA>5
@7GN
TGGGCAGAGTCCTTCCAAGAAGCAGAAAAAAAAGAGAAAAACGTCAAGCAGTAAACATGATGTGTCAGCACACCATGATTTGAATATTGATCAATCACAGT
+
?@@D?D8D?CAFFFE;>?:<<C3A?CFFFI@GBFEFFCFFFEI6=;E@;AAEC;>>BDDB>BD;(;@>>A?BBBBB555>AB;>:A:::A(4:>::>@BB:
@7GO
CTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJIJJJJJHHBDFEEDEEDDD@CDDDDDDDEEDDDDDDDDDDDDDDDDDDDD
@7GP
GAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCAC
+
C@CFFFFFHGHHGGGIJIJJJJJJJFIEEIIJJJJJIIJJJJIIJIGIJJIHHHHHFFFFFEEEDDDDBDDBBDDDDCDD>CDDCDDDDDDDDDDDDDDDD
@7GQ
GTACAATGTCAGTGCCTATGATCAGAAGCCACAAGTGGGAATGAGGCCCTCCAACCCCCCCACACCATCCAGCACGCCAGTGTCCCCACTGCATCATGCAT
+
@?@FDFDFHHGGHIGIIIGIJIJJGGIIGICHIEEHHIIH@DGHIIIIIGIIJIIIGIJHFDDDDDB@CBCACCD8;@@@4>:ACCDDD?CDCDDDDCCCD
@7GR
GAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGAC
+
CCCFFFFFHHHHHJJJJIJJJJJJJJIIJJJJJJGHJJJJJJJJJJJJIJJJHGHHFFFFEEDEEEDDDDDDDDDDDDDDDDDDDDDDDDDDDDDEDDDDD
@7GS
GAAGACTCGATCCGCCTGCCTGCGCACCTGCGCTTGCAGCCAATTTACTGGAGCAGGGATGACGTAGCCCAGTGGCTCAAGTGGGCTGAAAATGAGTTTTC
+
CCCFFFFFHHHHHJJJJJIJJJJJJJJIIJJJIJJJJJJJJJJJJJJJJJJIHHHHHFFFDEEDDDDDDDBDDDDDDDDDD:ACDDDDDDDDDDDC>CCDC
@7GT
TATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACC
+
@@@B=DDDFFHDFIIG@?H@><ACFHIEECF?FEGH@8?FH88BFHIID>CAGHIA=FHGCGDDAAEDCCBAC=?@>:>ACBCBB@<AC@@C@C?@CC@CB
@7GU
CTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGT
+
B@@FFFFDHHHHHIJIIIJJJJIJJIJJIJJJIIGIHIGGIGGIIJJJJIJJJJIJJJIJIIJJGIIHHHHHHFFFFDEDDDDDDDDDDDDDDDDDDDDDA
@7GV
CTTTTTCATCCACAGGCTGTATGTTTGAAAAGGGCCCCAGGCAGTTTTATGATGACACCTGTGTTGTCCCAGAAAAATTCGATGGAGACATCAAACAAG
+
:??DD?DD?<DFA3AFEA>G4BF,AA??9A+1888DFEBG;?DFF>@F*BF8C<B8=@F3=).===.=AAA;B>B?;(;;1@>;355(8(5>ABBA?@(
@7GW
GCAGGTCCCATCAGTCTGAACAGTAGTCCGGATCCATTTTTTGGATGGCACCAGAAGACATAAGAATGGAAGATAAAACCCCATTCAGCTATCAGTC
+
5-(28(98())2.):).@??<)4)))3).(((-;>>?>??)(5/<3)7)6696;>0))).8.8.8;?;08)67(.(=<((,'(5(:(((((,(+((+
@7GX
GAAGATTTGAAAGCTGAGATTGTTTCTGCATCTGAATCCAGAAATGAACTAGAATTAAAACATGAAGCAGAAGTTACAAATTACAAGATAAAACTTGAAAT
+
@@@DDEFFHHHFDIGJJJJIIJIJIIHJJCGIHIGHGIJJCHGGIJIIEGIGHIIJJJIIIIHGEHIJJIIJJJGIIIIJHGGHHGDFCDFEECEEEDDDD
@7GY
GGGAGACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTT
+
CCCFFFFFHHHHFIJJJIJIJIHGIIFHIGHIJIJIJJJJJIJJIHFHFFFDDCDDDDDDEEDDDDDDEDDDDDDDDDDDDDDBDDBDDDDDDDDDDCDED
@7GZ
TTAGGATTGCAACTGGACAGATAGCTGGCGTGGATAAAGATGGAAGGCCTCTACAACCCCACGTCAGAGTGTGGGATTCTGTTACTCTATCCACACTGC
+
?@<DAA?BDB>FFHEBA??CCFHEHIDHIG8DHAGD?BBGDHIIIBGGHEDEE>FHAHHIIHE..?<3;(6.;=>2>C>A@@A;5@>:A>A?>9>89:>
@7H0
GTCTTGCAATCTCTGAAGATCATGTGGCCTCAGTGAAAAAATCAGTCTCAAGTAAAGGCCAACCAAGCCCTCGAGCAGTTATTCCCATGTCCTGTATAACC
+
CCCFFFFFHHHHHJJJJIGIJJJJIIJJJJJJJIHHIJGGIIGIIGIIHIJIFGHGIJJIGIGIJJJJGHGHFFDDCDDDDEDEEDDDCCCDDDDDEEEDD
@7H1
TCCAAAAGCCATGAAGAGATTAATGGCAGAGTGCCTCAAAAAGAAAAGAGATGAGAGACCACTCTTTCCCCAAATTCTCGCCTCTATTGAGCTGCTGGCCC
+
@CCFFFFFHHHHHJJJJJIJIJJJJIJJJIJEHIJIJJJJIJJJJJJJIHIIJJJIGJIJJJJIGIJGHHHHFFFFDFEDDDDDDDDEDDDDDDDDDDDDD
@7H2
AAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGC
+
@@CFFFFFFHHHHIJIIGHHHGIJIIIJJIGIFGGGIGJIJJJJJJIJHIJJJJJIJIIJJJIJIJGGGGGEHFFFDDDDBCDDEDDCDDDDCDCDDDC@D
@7H3
CTTGATTAGAGACCAAGGATTTCGTGGTGATGGAGGATCAACCACAGGTTTGTCTGCTACCCCCCCTGCCTCATTACCTGGCTCACTAACTAACGTGAA
+
CCCFFFFFHHHHHJJJJJIJJJJJGHJEHIJJJJJJJJJJJJJJJJJJFHIJJJJJJJJJJJJHFDDDDDDDDDEEDDDDDDDDDDDDDDDDDDDCDDD
@7H4
CCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGC
+
@@CFFFFFGGHHHIGGHJJJIJJJGIJGIIIIHGIJIGJFGGIIFGIJJJEHHGHHHFFFFFFFDDDDDDDCCDDDEDDDDDDDBDDDDDBDDDDDCDCCD
@7H5
AGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACA
+
@@@DDDDDBHFFHEFH@@F?C?CFBEEHGGGIIIBGHGIIIFIIIIIIGGG@FGGG>FGIGHGHDHGHBHHEEED>A@@BA25???B<ACCCC>CCCCC>
@7H6
CGATGAGGTGGCCAGGCGCTGGGGCGAGCGGAAAAGCAAGCCCAACATGAATTACGACAAGCTGAGCCGGGCCCTCCGTTATTACTATGATAAAAACATT
+
@@@DDFFFCFFFDGIGIIIIBGGIGEAHIIFHFFFEEEEDDDDDDBDCC@CCDDDBDBDDBDCCCDDDBDBDBDDDBD?CDDDEDDDCCADDDDDDBBCC
@7H7
CTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTAT
+
CCCFFFFFHHHHHJJJJJJJJJJJIJJJJJJJJJIIJJJIJFHHIJIIJJJHHGHHHFFFFFFEEEEDDDDDDDCDDDEDDDDDDBBDDDDDDDDDDDDDD
@7H8
GGCCAATTGACAGCAACACGTTTGAAATGAATGGCAAAGCTCTCCTGCTGCTGACCAAAGAGGACTTTCGCTATCGATCTCCTCATTCAGGTGATGTGCTC
+
@@@FFFDFAFHFHGGHHIJJIJJIIIHFHGHAEGIIIFHIEDHIJJJJIJIIIEIJJJJEGGIBCGHHGHFBEFCBDBB@CCCDDDEEDDD5@ACDDDDDD
@7H9
GAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACT
+
CBCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJFJJJJJJIJJJJJJJJGHIJIHHHHEHDFEFFECECDDDDDDDDDDDBDDBDDDDDDDD
@7HA
CTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCT
+
;<??;8;>BF?CD1C<FHGIIIIBGBGGIBBGCD9BDF*?B?9/9BGCDHIB@A9C;DCC2@=8C?;B?>ABA3;?>CADDCC>55=@98?B<CCA9::9C
@7HB
GGGAAGGACGTCCTATGTACCAACGCCAGATGTCTGAGCCAAACATCCCCTTCCCACCACAAGGCTTTAAGCAGGAGGACCACGACCCAGTGTATGAACAC
+
:1122<A7AC?C<AB7?2<3++22:10??>*?:000=9ABAB7==A<).;AB>BABB6A=;66=@9>;>@@=;;;1;',99558059;==38+:=??;??;
@7HC
GGGGAGTTCAAAATGACGGACCCCGATGAGGTGGCCAGGCGCTGGGGCGAGCGGAAAAGCAAGCCCAACATGAATTACGACAAGCTGAGCCGGGCCCTCCG
+
BCCFFFFFHHHHGFIJJIJJGJIJIGIJGGCBGHIJIIJIGIIJJHGFD?BBDDDDDDDDDDDDDDDDDDDDCCDDCDBBDDDDDCCAACDDDDBBDDDDD
@7HD
TCTCAGCCCCAGCAGAACAAACCAAAGAAAAAGGAGAAAGACAAGAAGGAAAAGAAAAAAGAAAAGCACAAAAGGAAAGAGGAAGTGGAAGAGAATAAAA
+
C@CFFFFFHHHHHJJFIJJJJIJJJJJEGIJIHIHIIJJIGIIJJJJIJCHJJJJJJJJFFFFEEEDDDDDDDDDDDDDDDDABD:@CDDDDDDDDDDDD
@7HE
TTGGCTGTGGAGTTTCACCCAACAGATGCAAATACCATAATTACATGCGGTAAATCTCATATTTTCTTCTGGACCTGGAGCGGCAATTCACTAACAAGAA
+
CCCFFFFDHHHHDGIGHIIIJJJJIJIJJJIJIIIIJJGIJJJICGHGII@FHIGIJJJIJJJJJDIIJJJHHEFHFFFFEDDDDDCDCCCDDDDDDCDD
@7HF
AGCGAGGGAAAGCAGCCACGGTTCTAACTGGCAAAGACGGAGGCCATGGAGGGCATTAGCCAAGGTGGGGGTTTGGAGCGGCCCCAAGAACGCCCCAAAGG
+
0(((((((0.6())2(2=)((--8))01)))().0)0)7='-3(((.)))(7='39((((6((,6((7'3&05529/(()50008562(+()&0856(+++
@7HG
GTGAAAATGAAAAGTTCTGTCTTTGATGAAGACAAAACTTTTGTAGCAGAAACATTGGAAATGGGTGAGGTTGTTGAAAAGGATACAACAGAACTCATGG
+
?:=A?DBDHAHDBF@FDBIIHIHGIIGHIIIEHDGHGFGEIGI?FGHIIHICCHEIIF?D>FHFBGEGDC7@A@EAEEH@@?>@C(6;CD?C@A>AC>CC
@7HH
CCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJBDFFEEEDDBDDDDDDDDDDDDDDDDDDDDDDDACDDEDDDDDD
@7HI
TTTCAGTCAGATGTATATGCATTTGGAATTGTTCTGTATGAATTGATGACTGGACAGTTACCTTATTCAAACATCAACAACAGGGACCAGATAATTTTTAT
+
C@CFFFFFGGHHHFGIGIGGEHH@FGIGHIJHIGJGIIJHGGGIGIJIGJJHDEHHIHCGIGGGIIJEIIJGGIIGIIHIDEEEHADDDFEDEEEEDDDDC
@7HJ
GGCAATAAATGAACTGAATATAAAATTGCAAGATACTAACTCTCAAAAGGAAAAACTCAAGGAAGAACTAGGACTAATTTTAGAAGAAAAGTGTGCTCTAC
+
?@@DDFDFHFHFHGIHGGGIJIJIIGEIIIIIGGHIGGGJHGEHIIJIIDHIGGEEHIIDFIIIGGHGIIFBHIGHEHHGFFFFFDDEEEE>C>ACDDDDD
@7HK
CCAGTCGCCTAGCCACCCCTGGAAGCGGGCAAATCCAGCTGTCGCAATCCCTCCGGGACCTGCTCTCCGACGGCCCCAGCGCCAGCTGTATCACCTGGG
+
-5;=@)93(8>>@@1.(2<(=7.@@@(6((<(..<.=>136))76'',))..63',3''((,,(((+(5&&&&&&&)((+8&00552:8:/(4628/((
@7HL
CCTGAAGCCGTCCACACTGCGTGAGCTGGAGCGCTATGTCACCTCCTGTTTGCGGAAGAAAAGGAAACCTCAAGCTGAGAAAGTTGATGTGATTGCCGGCT
+
@@<D?D:DFA@FHDHGG>EH@FGGHIDGECEFD<DGGGGGABFCEHGGHEGIIIBBB>@C@@???CCCBACC>:>:@CBAC?C+:@CA>(:>DDACC99@<
@7HM
CGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJHHHHFFFFFDDDDDDDDDDDFDEDDDDDEDDDDDDDDD
@7HN
CTATGACAAGCAGGGGTGCTGAAGGATCAGTTTCTAAAGTAAATAAAAGTTTTGGTGAAGAATCAAAAATAATGGTGGAAGATAAAGTTTCTTTTGAAAAT
+
CCCFFFFFHHGHGIII@CFFHFHGEEGFGHHIIIIIJII?DHIIJIGJGGGIJIICHGGGIJGJIJCEHEHDFFF;@?ACEDDCDDC;@CDDCDDDDDDDC
@7HO
TCCGCTATTACTATGAGAAAGGAATTATGCAAAAGGTGGCTGGAGAGAGATATGTCTACAAGTTTGTGTGTGATCCAGAAGCCCTTTTCTCCATGGCCTTT
+
@C@FFFDFHGDHGJIIIIJIGIHIJJIJIIIJJJJJDHHEGGGCCGHIIGGEGGIIJJIJJJJIJIAGEC=CCHFCFFFECEECDCDDDDDDCADDDDDDD
@7HP
AGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACT
+
CCCFFFFFHFHHHJJJJJJIJJJJJJJIJJJJJJJJJJJJJJJIHIJJJJJHHHHHFFFFFEEEDDDDDDDDDDDDDDDDDDEDDDDDDDDDDDDDDDDDB
@7HQ
GGAAAGTGAAATTTCAACCACAGCAGATGACTGCAGTTCAGAGGTAAATGGTTGCAGTTTTGTGATGAGAACAGGAAAGCCTACAAATTTATTAAGGGA
+
CC@FFFDDHHHHHJJJJJJJJJIJJIIJEHIJJJJJJJIGHIFFBGIJIJJFGIJJJIJJJGFGIGHIIJJJJJHHHHHFFFFFEEEEDC@DDDDDDBD
@7HR
ATTTGAAGCTGCCATTAAACAAAGAGATGGCATTATAACCCAGCTCACTGCTAATTTACAACAAGCAAGAAGAGAAAAGGATGAGACAATGAGAGAATTTT
+
@@CDFFFFHHHGHJJIIIEGIGHIGIGEEEIGGDHDFFHIJGG@FFHGHGFBGBFHHIFHHHHHC=FCHIIIGEAHHFFDF>>ACE@CCDDD@CABDDDCD
@7HS
CTTGGATTATAATCATGAGATTTTAGGACAGCAAATTAATGACTTTACCCTTCCTGATGTGAACCTTATTGGGGAGCATTCTGATGCAGCAGAGCTTGGA
+
@@@DDFFFFDHHHBHGGIGIFIEHIGGFGIBEGICFHIIGIIHIHIJJIDGHJJEGGIJIDGE>FDHDHIIEC8DEEDFF>DECEDDCACDDDDDDCCDC
@7HT
CCACTTTGGCAGATGAAGCTCAGTCTCTGAAAGATGAGATCGACGTGCTGAGACATTCTTCTGATAAAGTATCTAAACTAGAAGGTCAAGTAGAATCTTAT
+
@@@D=DDDB8:CACGIFF<FFFI<:?CD@HHIIIFIII<9?FE<D?BBFI*8.=CFFDGEC>CCEEF=C77?AEFEDB>>BBAAC>6;;;(5>AB;5:ABA
@7HU
CACAATGCAAATTAGTTTCTTGCAAGAGAAAATTAAAGTATATGAAATGGAACAAGATAAAAAAGTAGAAAACTCAAATAAAGAAGAAATACAGGAAAAGG
+
CCCFFFFFHHHHHJJIJJJJJJJJJJJJJJJJJJJJJJGIJJJJJJJJJJJJJJJJJJJJJJJJJCHIJJJJJHHHHHHFFFFFEEEEEEDDDDDDDDDDD
@7HV
CTGGGCGGTGTAAGCACTGTAGCCCTGCTGCGCTGCAGCTTGGCTATAGGTACTGTAATCCGTGGACGCCATTTTCTCTCCTTCCTCCTCGTTCTCTCAAC
+
@@@??DDDD?FFB>HIIDA:?CEGGEH99BDHG@ABEFEHIIIEHHFHFF7?;;@;?C>@;=5=>?ABB?BBCAC@>C4(+:CCCC:ACCBBB1?@>C4:A
@7HW
GCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATAC
+
;?@DFFFDHGHHBGGIG?@EFHIJGHHIIFGIGGIGIIGIIBFBGEGIJJGIEFBHGIEHFEHFFFFDEEEEDDCCB@2;C@CD3>39<:AACDCDCDADC
@7HX
GGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTC
+
CCCFFFFDDFHHGIIIGHIGGIGGGHGHIJIJJGIIJIGGGGIIIJGIIIIGIAGHGI@=DGGGFFHEFEFBDFCECEA=BBACDDDDDD@DBABCB(4:
@7HY
CACAGCTTCTATTTAGTCACGAAGAAGAGCTTTCCAAACTGAAGGAAGATTTAGAAATTGAACATCGAATAAATATTGAAAAACTTAAAGATAATTTAGGC
+
@@@DD?BDHDHHFIIGFDDFF@FIEHHED?EEHGIHF@FFFDBDGDEHBDGHGHGGIGGIIIIIGGIIGGIFHEHHHFDEEEECCCCCCCCCCCCDECCCC
@7HZ
CTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAACCTCCCACTGGTT
+
?@@BDDDDF<F?FHGEEH<@C>CFGIFAGABCF@@:?@@DFEA3?F@F@FB>?B:<C9CFGIAD68?,9;(6>>>AA@C;@>::@@@(,5>?A<9<8A?4:
@7I0
CAGCTTTCAGTCAGATGTATATGCATTTGGAATTGTTCTGTATGAATTGATGACTGGACAGTTACCTTATTCAAACATCAACAACAGGGACCAGATAATTT
+
CCCFFFFFHHHHHJIJJHJIJJJJIJJJGIJJIJJIJJJJHJIGIJJJJJHIIIJJJJJJJJJJJIIJJJJJJJJJIJJJJJJJHHHGFFFDDEDDCDDEE
@7I1
ATCAGATCCGAACTACACCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATGACATCTCCTGTGACTCTCACCTCTCAGACAACTAAGACAGATGACCCC
+
@<@D?DDDB?FDDGFEDBEEC?B9HGCDEEEFG9@?D@<DGGEEG4?D//9?D<@3<=BD>;@=@GC)=;CAACEEB@CD@CAC;>>>;>>>;35>@5><5
@7I2
TTTAGCATTCTTGGGGAATGGAGATGTTCTTACTGGAGACTCAGGTGGAGTCATGCTTATATGGAGCAAAACTACTGTAGAGCCCACACCTGGGAAAGGAC
+
@@@DFFFFFHHHHIIEIGGEGGH>D?HCHGCDE<FHIIDGGHIGH@?;FB0BBFFAGIEEEGGG@8CHEGAE>EEECDD;@?DCDCC?DBCCD@ACAABD?
@7I3
CTGGAGAGAGATATGTCTACAAGTTTGTGTGTGATCCAGAAGCCCTTTTCTCCATGGCCTTTCCAGATAATCAGCGTCCACTGCTGAAGACAGACATGGA
+
CCCFFFFFHHHHHJJIIJJJJJJJJJJJJGGHIJJJJJJJJJJJJJJJJJJIJIJJJJJJJJJJJJIJJIJJJJHHHFFFFEEEEEEDDDDDDDDDDDDD
@7I4
CCTTGATCGTCAGCTGAAGAAAACTACAGAGGAACTAAATGAAGCTTTGTCAGCAAAGGAAGAAATTGCTCAAAGATGCCATGAACTGGATATGCAGGTTG
+
@@@DB4D:D?CA?<??3AF4C@3<FHFF?9CG8:::?B?DBB<<FFCGIB?BB<?F9;CBFCCEA:@EF;===E@7=;337@;A;>;AB?A3(5>A@<9@<
@7I5
GCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTC
+
CCCFFFFFHHHHHIJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJIIJJJIIIJJJJJJJHGHHHHFFFFFFDDDEEEDDDDDDDDDDDDDDDDDEDEDDDD
@7I6
CCCACCACAAGGCTTTAAGCAGGAGTACCACGACCCAGTGTATGAACACAACACCATGGTTGGCAGTGCGGCCAGCCAAAGCTTTCCCCCTCCTCTGATG
+
CCCFFFFFHHGHHJJJJJJJJJJJJFGIJJJJJJJJJJIIHIIJJJJIIJJJJJJJJJHHHHFFFF@CCDDDDCBBDDDDDDDDDDDDDDDDDDDDDDED
@7I7
CACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCA
+
CCCFFFFFHHHHHJJJJJJJJJIJIJJIIIJJJJJJJJJJJJJJJJJJJJJJJJJJIIJJHHHHHHFFFFFFEEECDDDDDDDDDDDCCDDEDEDDDDDD
@7I8
CACGGTGGCCGTGAAGATGCTGAAAGAGAACGCCTCCCCGAGTGAGCTGCGAGACCTGCTGTCAGAGTTCAACGTCCTGAAGCAGGTCAACCACCCACATG
+
CC@FFDDDHFHCF@FG@FEFHIJJJIIHBDHIIJJJJJIJBG;FEGGEHDBHEBEDEEDCECCDDDDCDCDEDDADBDDDDDDDDD2@CACBBDDDDD@DC
@7I9
CCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCAC
+
CCCDFFFFGHHHHJIJJJHIJIIJIHIIJIJJJIIIGGGEHIHIJIGGHGJHIIGIJGIIJIGEGHGHHFFFFEEECEDCDCCCCCCDC?BDBBDCCCBDD
@7IA
CCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTAT
+
CCCDFFFFHHHGGJJJIJIIGIJJGIIIIJIIIJHIIJIGIJJIJJJIIJIHHHFFFFFEEECECDDACCDCDDDDDDDBDDDDDDEDDDDDDDDDDDDDD
@7IB
CATAATTACATGCGGTAAATCTCATATTTTCTTCTGGACCTGGAGCGGCAATTCACTAACAAGAAAACAGGGAATTTTTGGGAAATATGAAAAGCCAAAAT
+
@<@?ADDDHF?FDBGHEFECEDH@E4CEHIEGC<EFG9DDEGBFE@?@GEICE=)=DHAHHCE>C?CD?AA?=?BC>CCBBBBAB5:>@C@@CC@8<CCBC
@7IC
ATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCA
+
CCCFFFFFFHDFBCGEGIIGIG@HHHGIIJEEICEGGIIIIIIIIGCFHIGDHIGIJEIIIIJIIGHHHFFFDEDCEEDCCDDDDDDDDDDDDDDDDCCE
@7ID
TGAAGACAAAACTTTTGTAGCAGAAACATTGGAAATGGGTGAGGTTGTTGAAAAGGATACAACAGAACTCATGGAAAAACTTGAGGTAACCAAGCGAG
+
@@@FDFFFHHHHHJJJIFHIIEIJJIIJIJJIHIGIGJJ?FGFIFGGHJJJJJJJIIJIIIJGIIJJJHGHFEFFFFFFDEECECD;ACCACBDBDBD
@7IE
GTCACCACCACCCAGGCCTCCTATGCANNNNNNNNNNNNNNNNNNACTCNNNNNNNNNNNNNNNNNNNTGNGNANNAGCCAGCAGCCACTGCACCTACA
+
@@@DDFFFHHHHGGIEHIEHGIIGIEI##################--5@###################,,#,#,##,,8?@?BCADB@CDDC:@CCCCD
@7IF
ACTGGATATGCAGGTTGCAGCATTGCAGGAAGAGAAAAGTAGTTTGTTGGCAGAGAATCAGGAATTAATGGAAAGACTCAATCAATCTGATTCTATAGA
+
???DDD>B?8D:2?EAA:33AA3AE4<<ACE?ECEB?1:1?DED<D9?DD?D=18=C4.88@)=3=A:==CAA>67?77;;6(;;AA>;5;535;5>>;
@7IG
TTTCTTTTGAAAATATGACTGTTGGAGAAGAAAGTAAGCAAGAACAGTTGATTTTGGATCACTTACCATCTGTAACAAAGGAATCATCACTTAGAGCAACT
+
CCCFFFFFHHHHHJJJJJJJJIJJJJJJJJJJJJEHHJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJHJJIHHHHHFFFFFEEEEEEEDDDDDDDD
@7IH
CAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGG
+
CC@FFFFDHHGHHJIJJJJJJJEJIGIJJJGIJIGHJGIJJIJGHJJJJJJHIIIIDHHIGHGJJJIGHEHFGHFFFDDEDDBDDDDCCDDDDDCCDDDDD
@7II
CGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCT
+
CCCFFFFFHHHHHJJJIJJJJJIJIIJJJJJIJJJJJJJIJJJJJJJJJJJJJJJHJJJJJJIJJJHHHHHHFFFFDDDDDDDDDDDDDDCDDDDDDDDDD
@7IJ
ACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGT
+
CCCFFFFFHHHHHJJJJIGIIJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJIJJJJJJJHHHHFFFFFDEDEEEEDDDDDDDDDDDDDDDDDD
@7IK
TAATCATGAGATTTTAGGACAGCAAATTAATGACTTTACCCTTCCTGATGTGAACCTTATTGGGGAGCATTCTGATGCAGCAGAGCTTGGAAGGATGCTTC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJIJJJJJJJIJJJJIIJIJJJHHHHGHHFFFFFEEDEEDDDDDDDBDDDDED
@7IL
CAAGAATGCAGTGAGCAAAATAACCAAGAAATAAAAAACATGAAATTAGACCATACTAATTCTAAGCAAAAAAGAAACACACGCCTCTGAAAAAATAAAAC
+
((02-2)).:2@))).2.<).6).66:@?<99;86@:6/=1)0>?33<96)0).9)768).))).)9).;3:;===5(((,'',((,37=<(865(((+6(
@7IM
CAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATAT
+
@@<=BBA?=AD>C?EBG<AEFFHGCHG@?;FHEIICH@CGBHIIIIEFDBBGH=FFHIEDHIBBAACH>>;??CCCCCA;>?BC=BACCC?C5@CCDCA
@7IN
CTAGAATTAAAACATGAAGCAGAAGTTACAAATTACAAGATAAAACTTGAAATGTTAGAAAAAGAAAAGAATGCTGTGTTAGACAGAATGGCTGAATCAC
+
1???+22=DA2:C+AE4EBAFC3AF,+AAAAC9??1?E?)1???BBDDI:D<???BDEICEI;67@77856=7)=C7=7A7@;?777..6@(5=;;;A>>
@7IO
CAGAAGTGCCTAGCTGCCACTCCATTTATATGAGGCAAGAAGGCTTCCTGGCTCATCCCAGCAGAACAGAAGGCTGTATGTTTGAAAAGGGCCCCAGGC
+
CCCFFFDFHHHHHJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJIJHHHHHFFFFFFEEEEEEDDDDDDDDDDDD
@7IP
CAGGGACTTCAGACATTAACCGTGACAAATTCAGGCAGTACTCAGCAAGGTACAACTATTCTTCAGTATGCACAGACCTCTGATGGACAGCAGATACTTGT
+
CCCFFFFFHHHHHJJJJJJJJJHIJJIJJIJJJJJJJJHIIJJJJJJJJJBFGIIEIIIJGIJIJJIJJJIJIJGGHHFFFFFFEEEEDDCDDDCDDDDDC
@7IQ
CCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCC
+
C@@DDFDBFFFDHFECFFFHGIAEHBFDFHGHEGDFEEFIGHGCEHGGIJICEHIFEIIJJGHHGDDBBECEDDDBACDDEDCCCCDDDDDBBACDDC@@?
@7IR
GGAGATATGCAAACATATCAGATCCGAACTACACCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATGACATCTCCTGTGACTCTCACCTCTCAGACAAC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJGHICGIJJJJHHHHHHFFFFFFEEEEEEDDDDDDDDDDDD
@7IS
CAGATACTTGTGCCCAGCAATCAGGTGGTCGTACAAACTGCATCAGGAGATATGCAAACATATCAGATCCGAACTACACCTTCAGCTACTTCTCTGCCAC
+
CCCFFFFFHHHHHJJJJJJJJJJJJHHJHJJHIJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJHHHHFFFEEEEEDDDDDDDDDDDDDDDDDDD
@7IT
CCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCT
+
@@@DDDDD>ADBFGAFH@HHHG>F@EGFCGGG<F>>GGBF?FHGEGECHHGEGFHGGDHGFF7?;@CCCCA?2=?BCB:@AC>ABB55>C989@?CB49CC
@7IU
GCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATAC
+
@@@FFFFFHHHHGJJIJIGIIIIJIIJJJGIJIJIGJJGJIJIJJJJJJJJJJHGGIJHHHHHFFFFDEEEEDDDDDD@BDDDDCDDDDACDDDDDDDDDD
@7IV
GGTGATTCCACACTGGGGTCTTCCAAAGAAACCCTTCCACCCACATGCCAAGGCAATCTCCTTATCATGGGGACTGAGGATGCCTCCTCCTTGCCTGAAGC
+
@B@DDFFFHHHHHJJJJJCGIJJJJJJJJJJJJJJJJJJJJIJJIJJJJJJIJJJJJIJJJJJJJHHHHHFFFDDDDEDCCDDDDCDDDDDDDDDDDDDDD
@7IW
GCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCC
+
CCCFFFFFHHGHHJJJJHIIJJJJJJJJJJJJJJJJJJJJIJJIJIGIIIJIJJJHHHHFFFDDDDEDDDDDDDDDDDDDDDDDDDDDDDDCCCDDDCDDD
@7IX
GTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCC
+
CCCFFFFFHHHHHJJJJJJIJJJJJJJJJJJJJJJJJJJIJJIIJJJJJJJJJJJJJJJHHHGHHFEFFFDEEDDDDDDDCDDDEDEDDDDDDDDDDDDDD
@7IY
GCCAATATGAAGGAGGTACCTCTGTTCAGGCTACGTCACTTCCCTTGTGGGAATGTCAATTACGGCTACCAGCAACAGGGCTTGCCCTTAGAAGCCGCTAC
+
???BDDD?DFF?ADFFC:ACBCE?3AAEFFFCFFBBFD@GFFF@FCE??AFD>AFBDFGED@DC@A<?7=B76?DA@A;???B855:@B:>:;:>@BB>@B
@7IZ
CAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTT
+
@@@DDFDDHBDDFHEH9CCHGGHEHIIJJJIIIIJCHJIJJGIJIIJJEHIJGIJJJGIIJJFHHHHCEFDFFFECEDDEECDDED@CDCDD:ACCDBCC
@7J0
TTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACC
+
;==AA47++<?A1++<A?A>BBC@<A7?=?@7A**1?7?7**0?AA<AAAB=A))77;=A><;>>)55>5(',9/393;9;=59(+3+8888838:::;8
@7J1
GACGGTTTCGCCGGCAGTCTCGATGATAGTATTTCTGCTGCAAGTACTTCTGATGTTCAAGATCGCCTGTCAGCTCTTGAGTCACGAGTTCAGCAACA
+
CCCFFFFFHHHHHJJJJJJJJJIJJJJJJGIJJJJJJJJJJJJJIJJJJJJJJJJIJJJHHHHHHFFDDEEEEDDDDDDDDCDDDDDDDDDEDDDDDD
@7J2
CACAACACCATGGTTGGCAGTGCGGCCAGCCAAAGCTTTCCCCCTCCTCTGATGATTAAACAGGAACCCAGAGATTTTGCATATGACTCAGAAGTGCCT
+
CCCFFFFFHHHGGFHGGIJJIIIIIIJIJIIJJIJJFGJIJJJJJIGGIGHHHGHFHHFFFFFDEDEDDDDBBDDDDDDDEEDDEEDCCDCDDDACDDD
@7J3
CCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTAT
+
@CCFFFEDHHGFHGGIJJJIJJJJJIGIIIIIIJIIJJGIIJJJJJJIGHIHHHFFFFFEDDCEDDDEDDDDDDCBBDDBBDDDDCEDDDDDDDDDCCDCD
@7J4
ACTGGAGCAGGGATGACGTAGCCCAGTGGCTCAAGTGGGCTGAAAATGAGTTTTCTTTAAGGCCAATTGACAGCAACACGTTTGAAATGAATGGCAAAGCT
+
CCCFFFFFHHHHHJJJJJJJIIJJJJIJJJJJJJJHIIJJJJIJJJJJJJHIJJJJJJJIJJIJJHHHHHFFFFFEEEDDDDDDDDDCDDDEDDDDDDDDD
@7J5
CTTATGGATAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACT
+
CCCFFFFF4CDHFIEIIIGJIIGHIJGCGIIJJJIJJIEIGIJJJIJIGIIJIJGIIJHFFFFFFFDEDDD;?DDCBCDCC@:ACDDCDDDACDDCCDB@C
@7J6
CCGTTCTTGATGGTGTCTGCATCGTCCCTTCGTAGCAAGAAGGAGCCAGCGCCCATGAAGAGCAAGCCCCCTCCCACGTATGAGTCGGAGGAAGAGGACA
+
??@?=BBDDFACF2A;<?AEHBFAGFGIGGIGCFF1CDFIIIGIDHEGIIGIGGIIIFFHFHEECDECCAB?BBBCB;9C:?CC:A<B@BBB@??BBBBC
@7J7
CCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTAT
+
@@CFFFDDHHGHD>EFHIHBFE@GHFDHGIGGIIDHHEGFHGHGAEHIGEDCEC;BCDFEEECCCCCDCCACABCBBBB???BCC@DCBCCBCCCBC9>CC
@7J8
GAAAGAGGAAGTGGAAGAGAATAAAAAAAGCAAAGCCAAGGAACCTCCTCCTAAAAAGACGAAGAAAAATAATAGCAGCAACAGCAATGTGAGCAAGAAGG
+
;-79=)=>?5@@19)=:(3.9?94:@??;;6:91=??9?79.333:>?>?3=3>?16'6)59=/=;><79;<5;0033(5;;22/8556++::7:<<9</6
@7J9
GTTTTCTAAATGAAGAAGTTAAATCTTTAAAGCAAGAGAAAGAACAAGTTTCATTGAGATGTAGAGAGCTAGAAATCATTATTAACCACAACAGGGCAGA
+
@@BFFFFFHHHFHJIJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJIIJJJJIHIIHIGIIJIJJJJIIJJJHHJJHHHHHHHFFFFFDDEDDDDDD
@7JA
GAGAATGAGAAAGTAGGATATACTAGAATATTTGGATTTACTAGTAGATGCTGATGTGATGAATGCATAGAAGGTTGAGGAAGGCCGGAAGTGAGTCG
+
+++2+++<?2,++2,2++33,,,,,3333A++2++**:7**1**11*****0*0****:0**/****0)/)))())))))).6-((,'9''(((-(('
@7JB
GTAAAAATAAACAGGAATTAGAGTATAAAAGTAAACTTAAAGCACTTAATGAAGAGCTTCATTTGCAAAGAATAAATCCAACTACAGTGAAAATGAAAAGT
+
C@CFFFFFHHGHHIJHIJJJJHIHHJJJJJJHHJJJJJJJJJJJJJJJJIIIJGIJJJJJJIJJJJJJJIJJGIJJIHIJHHGHHFFDFFFEEDCEEDDDC
@7JC
CTCAGTGAAAAAATCAGTCTCAAGTAAAGGCCAACCAAGCCCTCGAGCAGTTATTCCCATGTCCTGTATAACCAATGGAAGTGGTGCAAACAGAAAACCA
+
CCCFFFDFHHHHHIJJJIJJJJJJHHHJGHIJJJJJJJJJJJJJJJJJJJHIIIJJJJIJFHHGHHFFFFFFFFDEEECDD@AC@BDDDDBDDDDDDDDD
@7JD
TGGAGTTTGTCACCAGTGGAGGCCGGATGGACCCACCCAAGAACTGCCCTGGGCCTGTATACCGGATAATGACTCAGTGCTGGCAACATCAGCCTGAAGAC
+
@CCFFDDFHHFFFIIIEHIIGGDEHGHHHIIECHEHEEGIEHJIGCGGEGGGHCCHEFDBDEFDD@BDCCDDCDDDDCDCACCDDDBDDDDDDDDDCDDDD
@7JE
GTGCGGCGCCTAGAGGGAAAGCGAGAGGGAGACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGC
+
?=?D?DDDDDAAHEG>D@DGHGD?D:AGGGGIGCEHECCBCBCBC@?>;88;BB8<8A?8?BB@ACCCACBBBBB(:?5@BBACCC@>CCC:@>3>ACCBB
@7JF
CCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJIJJJJJJJJJGHIJJJJJJJJJJJJHHHHFFFFFFEEEEEDDDCCDDEDDDDEDDEDDDDDDD@CDDDDDD
@7JG
GGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTT
+
===<A>A;CC8+?+??A++<33++22?>7A*74@3):??=7=A):>BBBB9:A=AAA<>A3(.=)7>37;.49',5(5;:==;=;0+83(83+2(())9;
@7JH
CCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGAC
+
@@@DDDDDFFDDFEHGEBGCG@AEGGGHGGGGHIFGGHIECGHGCD@FFBCAAFGGGHIIIGEH@@C>CECDEDDBC?B@?AA9A>;>C:;,:?9<B@B<?
@7JI
CTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJIJJJJJJJIIJJJJJJJJIJJJJIJJJJJJJJJJJIJJJJJHHHHHHFFFFDEDDDDDDDDDDDDDDDDDDDDDC
@7JJ
GGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACAC
+
?;;=BD;:=CFB??FGDA,CFFA<CF?F+2+1??;118C;FHIGG73B;9BEB28CHCCFIIICD===?=?=77..6;;=CA;?;C?>(>:55>CC:::<
@7JK
CTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCGTGGGTGTT
+
CCCFFFFFHHHHHJJJJJJJJJJJJIJJJJJJJJJJJJJIJIJIJJJJJJJIIJJIIIJJJHHHHHHFFFFFFDDDDDDDDDBDDDDDCDDD&9<BD<BDD
@7JL
CCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCT
+
CCCFFFFFHHHHHJIJJJJJJJJJJJJHIJJJJJJJJJJJJJJJJJJDHGJJJJJGHEIJJJJJJIHHHHHFFFFFEEEEDEDDDDDDDDDDDDDDDDDD
@7JM
GAACCTGTCAACATACTAGATGTTAAAGATGACTGTGGCCTCCAACTAAGGGTCAGCGAGGACACCTGCCCACTGAATGTTCATTCTTATGACCCCCAAGG
+
@@@DFBDDFH?FDEHEEHCHHGHEDDEECCCBH<C??CBFDC@GCGGEGGIIBDCHH@FA45@DCE37?@BCBAACEEECEEDED@>5;>:>>@ABB&288
@7JN
CTCCTCTTAACCATCATCTTCTCCAGGTCTTTGCTGATGTCCGCAAACACCGGCCTTTTGTCCGGCTCCTGCTTCCAGCATTGCAGCATCAGGCGGTACAT
+
@@@DDDDDDH?F<A:<E<AHC<?::CE+299<A?9??CD????::??FHD;F@;;@ECH4=.7;?499555@;;;-5:5,5>A:C:55>(+44355005>C
@7JO
GGAAGGACGTCCTATGTACCAACGCCAGATGTCTGAGCCAAACATCCCCTTCCCACCACAAGGCTTTAAGCAGGAGTACCACGACCCAGTGTATGAACAC
+
@CCDDDFFHHHHHJJJIGIGIJJJJJJJIIIFGHIIIIIIJJJJJJJJIJIIIIIJJJGHHHFFFDEEEEEDDDBBCCC>CCDDDDDDDDD>CDDDEDDC
@7JP
GGAAGAGAATAAAAAAAGCAAAGCCAAGGAACCTCCTCCTAAAAAGACGAAGAAAAATAATAGCAGCAACAGCAATGTGAGCAAGAAGGAGCCAGCGCCC
+
BC@FFFFDHHHHHJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJIIHGIHHHHFFFFFEEEEEEDDDBDDDDDDDCDEDDDDDDDDDBDDDDDCDDDD
@7JQ
CCTTCTCCCCAGCCCTCTTCACAACCTCTCCAAATACACAGACAAACTCCAGAAAGCAAGAATGCTACTCCCACCAAAAGCATAAAACGACCATCACCAGC
+
<?@D:?B:CD>BFGFF3C@?93CFGBCG<FG@;FDFEGFF?;?;?0?DFCFFFFIIIII>=7C;7=E=?AAE3;BD=@?A9?5;A@@B===@B:>A@?A8?
@7JR
CTTAGAGCAACTCAACCAAGTGAAAATGATAAACTTCAGAAAGAACTCAATGTACTTAAATCAGAACAGGACTTGATTAGAGACCAAGGATTTCGTGGTG
+
@@@DDEDDHDFDHGGIGIIIJGIGBD@FEDHHGIJJGIGGHGIIGJGIIFHHBBDGIJGCFGGBHGHGGG>CCGGCHHHEEEFDFFCA@@CCCDD;;??@
@7JS
TCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATG
+
?@<DDEFFFHHHHIIBEEGHHIIIGIIIGGHG@FHIIDGG<@GIIIGGGIIHEEHHGFFFFFFEECAADDDDCDDDDDCCDDCBDBBDDD@@D@ABDDDDD
@7JT
CCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGT
+
@@@DFDEFHHGHHJIGIJIF?FHIHIJIJGIJJIIJJJJJJJJJJJIIJJIJGEHHHHFFFEEFEEEEEDDDD;ACDDDDD?BBDDDDDDDCDCDDDDDDC
@7JU
AATCATTGAAGAATTAAACACAAAAATAATAGAAGAAGAAAAGAAAACTCTTGAGCTAAAGGATAAATTAACAACTGCTGATAAATTACTAGGAGAATTAC
+
CCCFFFFFHHHHHIJJJJIJJJIJJJJJIJJIJIJJJJIIJJIJJIIJJJJJFGIGJJJJIJIGIJJJJJIHIIFHHFEFFFFFFFEEEDEEDDDDDDDDC
@7JV
TTTTCATTTGCTGAAAAAAACTTTGAAGTTAACTATCAAGAGTTACAAGAGGAGTATGCTTGCCTTCTCAAAGTAAAAGATGATTTAGAAGACAGTAAAA
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHIIIJJJJJIIIGHIJJJJJJJGIIHHHHHHCDFFFFDEEEEFEDDDDDDDDDDEDDD
@7JW
AACTCTCAAAAGGAAAAACTCAAGGAAGAACTAGGACTAATTTTAGAAGAAAAGTGTGCTCTACAGAGACAGCTTGAAGACCTTGTTGAAGAATTGAGCTT
+
@@@FDFFFFHHFHIJJJGIJIJJIJJJJJJIGIBHJJGJGJJJJJGIJJJIIIJ?FFGIIAHJEHIGGIJJJHHHHHFFFFFEEECEECCDCDDCCDCDDD
@7JX
GACCAGCAGATGAAGATCATCGAAATCAATTTGGGCAACGAGACCGATCCTCATCAGCTCCCAATGTGCATATAAACACAATAGAACCTGTCAATATTGAT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJIJJJJJJJJJIJJJJJIIJJJHHHHHHFFFFFEEEEEEEEDDEEEDDDD?CDDDDDDDDCDDEEEDEDCE
@7JY
AGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJIIIJJJJJJJJJJJJJJJJJJJJJIIGHHFFFFFEEEEEEEDDDDDDDDDDDDDDDDDDDDDDDDDDDEDDDCDD
@7JZ
AGAAGATTGAATTCCTGAAGGAGGCACATCTGATGAGCAAATTTAATCATCCCAACATTCTGAAGCAGCTTGGAGTTTGTCTGCTGAATGAACCCCAATAC
+
;:=B?DDDDHBFHIGED<<AA?3<F8F?<GCEI>G??FHIDGEGIIIAHGEHIHIIGIIEC8CHIIE=DHIGG>A37?76;@D?C;>@;;;@C;;@@8<@>
@7K0
GAATAAAAAAAGCAAAGCCAAGGAACCTCCTCCTAAAAAGACGAAGAAAAATAATAGCAGCAACAGCAATGTGAGCAAGAAGGAGCCAGCGCCCATGA
+
CCCFFFFFHHHHHJJJJJJJJJJJIJJJJJJJJJJJJJIJIJIIIJJJJJHHHHHHFFFFFEEEEEDDDDD@DDDDDDDDDDDDDDDDDDDDDDDDDD
@7K1
GTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTAC
+
@C@FFFFEHFAFHGGEGHBFGGIIJGB@GFHIGGHHEGJJJJGGHIGIIEHJJJCGIJGGCHGD@HHGGHH=@@D>CCBEDCCCCCCDADDDDDACCBCCC
@7K2
GCAGGAGTACCACGACCCAGTGTATGAACACAACACCATGGTTGGCAGTGCGGCCAGCCAAAGCTTTCCCCCTCCTCTGATGATTAAACAGGAACCCAG
+
CCCFFFFDHHHGHJJIJIIJIIGHEGHGGIHIJJJIJJIIJHEHJGIIFHHIGEHEEFDEDEDDCDDCDDDDDDDDCDDDEDEEEEDDDDDDDBDDDBD
@7K3
CTCCGGTCCCCCCTGGACAACATGATCCGCCGCCTCTCCCCGGCTGAGAGAGCTCAGGGACCCAGGCCGCACCAGGAGAACAACCACCAGGAGTCCTACCC
+
???B+00<)+<8)?;C3CDBDD?@<DEI21B@A<';7@D>AA<<99>((5(55(:5,:5<<?<(22<?>>99><<<(2((++3<?<88<822839>A>3++
@7K4
GGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGAT
+
@C@FFDEFHHHHHIIJJIIIJJJJJJJGJGJJJJJJJIHJJIIGIJJJJJJJJJJJIHHFFDDEDDDDDDDDCCCDDDDDDDDDDDBDDDDBDDDDDDDDD
@7K5
CATGTTCATTCCTTCCGATGTTGACAACTATGATGACATCAGAACGGAACTGCCTCCTGAGAAGCTCAAACTGGAGTGGGCATATGGTTATCGAGGAAAGG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJIJJJJJJJIIIJJIJIJJHHHHHFFBDDDDEEDDEDCCDDC?ABDDDDDD
@7K6
TGCCTGGATTTTTCAAAAGCAGATTCAGGTGTTCATTTATGTGTTATTGATGACTCCAATGAGCATATGCTTACTGTATGGGACTGGCAGAGGAAAGCAA
+
CCCFFFFFHHHHHJJJJJJJJJIJJJJJJCGHIIJJJJJJJGIIJJJJJJJJJIJJJJJJIIJJJIJJJJJJJJJJIIIJJHHHHHFFFFDDDDDDDDDD
@7K7
AAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGC
+
;?@DDFFFHHHFFGIFBFHEHECGE@?CBF4C:CDFDFH?BBGG@F?FGGGGIDHGACFFFHIGCDD7CHA?<BD?8?BBBCCCDC>CC>>A:@CCCCC8A
@7K8
CAGAATCCTTCCCCTAGAGCAGCTGGGGAGAGGGACGATGTCTGTCTCAGCCCAGGAGTTTGGCTGAGCAGTGAGATGGATGCTGTAGGCTTGGAGCTGCC
+
@@@FFFFFHHHHHJJIIJJJJJHJIJIIFHHHIJGIHHIIJJJJJJJGIJJJIJJHHFHFFFFFEDADDDC;AAA@CCCCCDBDDDDDDDDDDDCCCDDCD
@7K9
AGGACTTTCGCTATCGATCTCCTCATTCAGGTGATGTGCTCTATGAACTCCTTCAGCATATTCTGAAGCAGAGGAAACCTCGGATTCTTTTTTCACCATTC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJFHIJJIIJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJHHHHHFFFFDCDDDDEDDDDDDDDDDDE
@7KA
CAACAAGCTCCCCGGCGAGAAGCTGGGCCGCGTGGTGCACATCATCCAGTCACGGGAGCCCTCCCTGAAGAATTCCAACCCCGACGAGATTGGAATCGACT
+
??@DDDDDDDF=F<DFEA:D)BFGFEIIIIEE=BB.=A>@BA>A>A>AA;ABBBB?5908?BB@B?BBBAABABBBBBA5@@B-9>000<:ABBB@ABBB<
@7KB
CGACATGTGAATATCCTACTCTTCATGGGCTATTCCACAAAGCCACAACTGGCTATTGTTACCCAGTGGTGGGAGGGCTCCAGCTTGTATCACCATCTCC
+
@???DDEDBHHFDGHIIIGB>?EFEBBAFFFGFEG@DGHIE@BGHGEI=?@GGC8BHBBCCCFHHG)8==5(565=>8>=?>CCCCCB>ABDC<C>C:>C
@7KC
TGCTTCAGCTCACCCTAAGCTGTGCCGTGAAAAGTTGACTGAAACAATAAAACCTCTCAGCCCTTCTGATGCTGGGGGAATTTGTTCCACAAATTGGCTTT
+
70;9(<).<@1))(((...@>@))))((1(())1.))9=)):9)9.())))))(.))))):=(;.)8.)).)8);,,9,,,(((,(,((7(((((5(6(6(
@7KD
CTGGATTTCCTCATGGAAGCCCTGATCATCAGCAAATTCAACCACCAGAACATTGTTCGCTGCATTGGGGTGAGCCTGCAATCCCTGCCCCGGTTCATCCT
+
@@?BDDDDFHHDFDHF?E:ADFIHGGGGIIG>FDHIGDFGFHI@HGI;FDFABGG9=C;@@FEHDDEDEH9AC>ACC?BCCAA?@>AABBBBB9>@C>CCA
@7KE
GCAGTTACAAGCCTTCAAAAATGAAGTAGGAGTACTCAGGAAAACACGACATGTGAATATCCTACTCTTCATGGGCTATTCCACAAAGCCACAACTGGCT
+
@@@DDBDDDHFDFGHHHIJJIIIDGIHGGEIC:CFAGIIIEGGGHJJIEGHIGFGHHGIDGEGIGHIJFGEECEABFEDFEDECEDB>CDCDDDBCCDBC
@7KF
CAGCAGAAGGTGAACTTTGTCCCTCCCCATCCATCCTCCATGCCTGTCACTTCCTCCAGCTTCTTTGGAGCCGCATCACAATACTGGACCTCCCCCACGGG
+
CCCFFFFFHHFHHJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJHIJHHFFFDEEEDDDDDEDDDDDDDDDDDDBDD
@7KG
CCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJHIJJJJJJJJJGHJJJJJJJJJJJIIJJJJJJJJJJHHHHHHFFFFDDDDDDDDDDDDDDDDEDDDDDDDDD
@7KH
ACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHHFFDDDDDDDDDDDDDDDDBDDDDDDDDD
@7KI
AGACGAAGAAAAATAATAGCAGCAACAGCAATGTGAGCAAGAAGGAGCCAGCGCCCATGAAGAGCAAGCCCCCTCCCACGTATGAGTCGGAGGAAGAGGAC
+
@@@FFFFFHHDFFIIFJJJEHIJJGGCFGEFHIFHFFGIBHIFGGGIIIHHGIFIJHEHHEEDBDDCCCBBDDDDD@?B???CCDDA>95599?8A88AAA
@7KJ
CCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCAC
+
<@@DFEFFHHHHHGHIGHGIIJJIIIGHIJJJIJIIIJIJGJJJJJIJJIIIIIIJIIIGJIJJJHHHHDEBECEDFCCECDDCDDDDDDDBDDDDDDDDD
@7KK
CCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTTATGGG
+
@CCFFFFFHHHGHJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJIJJJJJJJJJJJJGIJHHHHHHFFDDDDDDDDDDDDDCDDDDEDDD>@BDDDDDDD
@7KL
CTCATACACCGAAACCTGACCGGGCCTTCCCAGCTCACCTCCCTCCATCGCAGTCCATACCAGATAGCAGCTACCCCATGGACCACAGATTTCGCCGCC
+
@CCFFFFFHDFHHJJJIJIJIJIIIJJJIGJGHHGJIEGIJIJIJGJIIFGGFDFDEFEEEEDBDDDDC@BDDDDDDDCCD@CDDDDDDCCDCC@BDBB
@7KM
CCAAAGATGATTATCGAATACGTTGTGAAGAGTTAGAAAAGGAGATCTCTGAACTTCGGCAACAGAATGATGAACTGACCACTTTGGCAGATGAAGCTC
+
?@@DBDBFADFHDF<EGHIICEHHIHGFD?D;?FE@4:B9CG>FGGDGCHHIICHC@FEGAEHGBHFEAECEDD?C;;@EC?CCCA?;>??@@@>:5::
@7KN
CCGATGTTGACAACTATGATGACATCAGAACGGAACTGCCTCCTGAGAAGCTCAAACTGGAGTGGGCATATGGTTATCGAGGAAAGGACTGTAGAG
+
?@@?DDDF?BFDFGHEFECFHCAEGGE><F?CB?D@@@<BFGII>BFGHEGFGGIG:B=CE@CEGIGEEEC>DCDE@>;6=?:ACB??A9<:B;>>
@7KO
ATTCAGATGATAGCCGTAATAAATTGTCGAAAATACCTTCAACACCCAAATTAATACCAAAAGTTACCAAAACTGCAGACAAGCATAAAGATGTCATCATC
+
@@@DFF>D?FFBDGEB@AAFGGGIGHIIIIGGEFED>FCBAFCBGGHHIIEFHEDEGGGGGGI=@=@CEEEBB@DDEE>ACCBCBACCCCACC@C>C@;A>
@7KP
CTAGAATCATAACAACAAATCTAGAATGACTGGAATGACTGGAAGGGACAGAACATTATAAAAAATCTCTGGGAGAATGACCAGGCATGAGGGCTCAAGCC
+
0(0((:))<))<..@>??1:=..223;))24>())).6):3:>>?99175(.)):1:1)38>;;;(<).))))65'((((.39((7(77((,,'((+((++
@7KQ
CAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTAC
+
@@@DDDADHFDHHGGGGGIIEGHHGHCFHHGICHIFGGGGIIJJIJGHIJGIEIDFAHHEHHJGEGGHAC=EB@DCE@@>CEEA?B?>C?>CDDBD??CCD
@7KR
CTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJIJJJIJJJJJJJJJJJJJIJJJJJJJJJJJJJJJHHHHHHFFFFFFDDDDDDDDBDDDDDDCCDCDEDDD>@<B
@7KS
CCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCGGTAGCATGGGCGATTATGGG
+
@1=DDDBDHDHHDHDHGGIB?C<C4E>BAG>B;FC@?FDGEEE;DGGD6D6;FFFGD?..=?;=?C;<'='(,;,=;<@:')090@A(4((+)&&22(((2
@7KT
AAAAAAAAAGAGGAATCTCATTCTAATGATCAAAGTCCACAAATTCGAGCATCACCTTCTCCCCAGCCCTCTTCACAACCTCTCCAAATACACAGACAAAC
+
@@@FFFFFHGHHHBFAGGEHIADCGHIICHIIIIIBBGEIIIIGGAGCEIEHHHAHFFEEFFEDEBBDDDDDDDACDDDDCDDCCDDDCDDCCDDDDDDDB
@7KU
TGGAATTGTTCTGTATGAATTGATGACTGGACAGTTACCTTATTCAAACATCAACAACAGGGACCAGATAATTTTTATGGTGGGACGAGGATACCTGTCTC
+
CCCFFFFFHHHHHGGIJJJIJJJJJJIJJJJJJIGJJJJJJJJJJJJJIJJIJJIIJJIJJJJJJJJJJJJJIJJHHHHH?DFDDDDDDDBCDDDCDDDDD
@7KV
CTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJHIJJJJJJJGIIJJJJJIJJJJJJJJJJJHHHFFFFEEDDEDDDDCEEDDDDDDDDDDDDDDDDDDDD
@7KW
CAGGAGAAGATTGAATTCCTGAAGGAGGCACATCTGATGAGCAAATTTAATCATCCCAACATTCTGAAGCAGCTTGGAGTTTGTCTGCTGAATGAACCCC
+
@@@=DDDBBHFFDEDBFHIIGDGG;FCADFFHIICG>DDB?<DHBGGHIGGB>CGEECB@FFG@@C@@GEGGCHFFE7@;@DCACCCCCCC@CCCCA?@B
@7KX
AGGTCATACTGCATCAGAACCATGAAGAAGATAACTGTGTCCAGAGGACCCCCAGGCCATCCGTGGATAATGTGCACCATAACCCTCCCACCATTGAACTG
+
B@CDFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIIHHHFFFFFFFEEEEEDDDDDDDDDDDDDDDCDCDDD
@7KY
GGAAGAGGAAGAGAAAGTGCCTGTGAGGCCCAAGGACCCTGAGGGGGTTCCTCCTCTCCTGGTCTCTCAACAGGCAAAACGGGAGGAGGAGCGCAGCCC
+
CCCFFFDFHHHHHJJJJGHIJIJJJJJJJJJJIJJIJJJIJJJJJJIAEHHHHFFFFEEEEECDDDDDDDDABDDDDDDBDDDDDDDB>DBBBDDDDDD
@7KZ
CGCAGAAAGAAGAAAGAATATGTGAAATGCCTGGAAAACCGAGTTGCAGTCCTGGAAAATCAAAATAAAACTCTAATAGAAGAGTTAAAAACTTTGAAGG
+
CCCFFFFFHHHHHJJIJJJJJJHJJJJJJJJIJJJJJJIIIIJGIJJJJIIJJJIJJJJGGJIJJJGHHHHHFFFFFFFEEECEEEDEDDDDDDDCDDDD
@7L0
CAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTAC
+
@?=B??AAF??BFHFEFBGDHIEFHIGIGE<C?C?DGIEIGGGAF@FHACEHIHCA?EHBFFDCCCCEA@C@?;ADCCBCCC@::5>>>>:ACAB@>)5AC
@7L1
GGCCTCTGAGGTTTGCCAGCAGCCAGTGTACATTCCGAAGAAGGCAGCCTCCAAGACACGGGCCCCCCGCCGGCGTCAGCGTAAAGCCCAGAGACCTCCTG
+
@<@DDDD?BFDDFCEBFHGBFHEH@CA??F@EGCGGII;FGGDD29?=?=FGEHG@FACB@=6=CBBB?BDD9B>B>BBC@@<@ADABD?BDB?CBCC?<@
@7L2
GTGATGTGGCAGTGAAAATGTTGAATGTGACAGCACCTACACCTCAGCAGTTACAAGCCTTCAAAAATGAAGTAGGAGTACTCAGGAAAACACGACATGTG
+
@?@DDFFFFFHF:EFFIGIIHIIIJIJDHCHGIJIJJIIIJJJCHIEGIHHGIJJGHBHFGEHHHIIJIGIJ@DHFAE?CFEBCFECECEDBDB@B@BD@C
@7L3
CAAAAAGAAAAGAGATGAGAGACCACTCTTTCCCCAAATTCTCGCCTCTATTGAGCTGCTGGCCCGCTCATTGCCAAAAATTCACCGCAGTGCATCAGAAC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJIIJJJJJIJJJJJJJJJJJJJJJJJJJIHHFFDDDDEDDDDDDDDDDDDDDDDDD@CDDEDDDDDD
@7L4
GTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTAC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJIJJJJIJJJHHHHHHHFFFFEEEEEEDDDDDDDDDDDDDDDDDDDDEED
@7L5
GAAAAAAAGAACAATTTGGATTCTTAGGCATGGTCTGAGCTATGATATCAATTGGCTTCCTAGGGTTTATCGTGTGAGCACACCATATGTTTACAGTAGG
+
7-98-((09(()).6981@;>)))26)=)96:7.).90<<?<1:>1))3)).8=;9)38;3)8=>.(57).6.6.9(:(((,3((,,((,572;(,(+82
@7L6
GTACAATGTCAGTGCCTATGATCAGAAGCCACAAGTGGGAATGAGGCCCTCCAACCCCCCCACACCATCCAGCACGCCAGTGTCCCCACTGCATCATGCAT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJFHIJJIJJJJJJJJJJJJJJJJJJHFDDDDDDDDDDDDCD;@DDDCCDDDDDDDDDDDDDDDDDDE
@7L7
GAAAAACATCACCCTCATTCGGGGTCTGGGCCATGGCGCCTTTGGGGAGGTGTATGAAGGCCAGGTGTCCGGAATGCCCAACGACCCAAGCCCCCTGCA
+
@@@DDDDDDD??DDDGIBHFHC?@HHII9?CBF;:?B@FFFA@=@B8;4=AB7;A@DCCCCA?=B;>A@A?;8,2@AC9>AB88<@BB<BB??@<&229
@7L8
AGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCAC
+
:1>A?A7=C=2<+@<C<7)222@C>7A751:7ABB<:700:9=>=A;>>7=7>B7A>AB=8=;=AAA;6;;;;;;@;;>>===;?=;55:;??:??B?9?;
@7L9
GCTATTCCTCTACACAGCCAACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGT
+
CCCFFFFFHHHHHJJJJJI+AFFHICIJIIGJJJJHIIJJIIJJJJIJJGIJIJJGIIJJJJIIEIIIJFHHFFFEDEEEDDDDCDDDDCD@CDCDECDDA
@7LA
AATGGACTTAAATCAGAACAGGACTTGATAAGAGACCAGGGATTTCGTGGAGGTGGAGGACCAACCACAGGATTGTCAGCAACCCCCCCTGCCTCATTACC
+
(((-(@.6?@84))@)).2.)(<())))<))).)))(:(:=?3:3=>(-7(((-9=(;??((6((',((.9(.(9(((7;(,82'',&5:-:6((5(+8(+
@7LB
GGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATC
+
CCCFFDDFHHHHHJIHIJJJJJJJJJIJJJJJJJJJJIIJJJJJJJJJJJJJJJJJJJ@GHGHHHFDFDEEEEDDDDDDDDDDDDDDDDDCDDDDDDDDDD
@7LC
GGGACTTCAGACATTAACCATGACAAATTCAGGCAGTACTCAGCAAGGCACAACTATTCTTCAGTATGCACAGACCTCTGATGGACAGCAGATACTTGTGC
+
?1+B;?;A222A:AEDE?3+AEFEEC++2A<FEEID?D4:C?99:DDD)?;;?(/*//88=BEE.==C<77=CADD>AA???ADAAA@@A2;A>AA>AA>>
@7LD
CCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACAC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJIJIJJJJJJJJJJJJJJJJJJJJJJHHHFFFFFFFEEEEEEDDDDDDDDDDDDDDDDDDDD
@7LE
AAATATTACAGTTAATGAAGATCAGATAAAGTTAATGAATGTGGCAATAAATGAACTGAATATAAAATTGCAAGATACTAACTCTCAAAAGGAAAAACTC
+
CCCFFFFFHHHHHJJJJJJIIJJJJJJJJJJHIJJJJJJJJIJJJJJJJJJJJJJJJJJJJIIJJJJIJJIJJIJJJJJJJIJJIHHGHHFFFFFEEDEC
@7LF
CTTCAAGAAAAATTTGCACAACTTGAAGCAGAGAATAGCATTCTTAAAGATGAAAAGAAAACCCTTGAAGACATGTTGAAAATACATACTCCTGTTAGCC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJIIJJJJJJJJJJJJJJJHHHHHHFFFFFFEDEEEEEDDDDDDDDD
@7LG
AGAAGATGATGGTTAAGAGGAGAGACTACTTGGACCTTGCGGCGTCCACTCCATCTGACTCCCTGATTTATGACGACGGCCTCTCAGAGGAGGAGACACCG
+
?@@DAB?DDFHF<CFFBFIIE;BF8AEHGFFHGGGE><AFDGE>@GGHGHHHHECCD:?@CCCCCCAC3>@CCA@BBBB<5<1:A:@:@88?<B?<@CCB9
@7LH
GAACAGATTGTGCAAAAGAACCAAGAAATAAAAAAACATGAAATTAGAGCTGACTAATTCTAAGAAAAAAGAAAGACAGTCTTCTGAAGAAATAAAACAGT
+
-(7934)..2..9?:..)-2.6><<@9:)=36=>?8=???>??9.=76)/)86=3:3=.>98?))<=97=,33;9;>892822,;7=::5;7(3:;6(2:+
@7LI
GCAATTCACTAACAAGAAAACAGGGAATTTTTGGGAAATATGAAAAGCCAAAATTTGTGCAGTGTTTAGCATTCTTGGGGAATGGAGATGTTCTTACTGG
+
@C@DFFFFFHHHHJJIIEIJGCHHHGHHIJGI@GGBFHGGHCIIIJEGDHFFHCHEG=CGAF7CHHGHH@CEH@CDBEFD?ADCCDB>CC@CDCCCCDCD
@7LJ
TGCCGAGTTACGCTTCCTCGACGCCACTTCATGTTCCAGTGCCTCGAGCGCTCAGGATGGAGGAAGACTCGATCCGCCTGCCTGCGCACCTGCGCTTGC
+
??1=:@DDD?DD::C@ED>12?:D0?@9DD??BEID?B8B<4CBC@44@-555=66.;;(-,5>555:55(9A?>28<58<<A42;5>00>>200)5<2
@7LK
ACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGT
+
@@@DDDDDFDHHDGIGEBHCFHH3<@?FH?G?DGHBBF@FGGIIIGHEBF6BGF@GGEC@=D77AAHBBA<BB???-;>CCBC>A@/<>BBB<?BBBBB<+
@7LL
AAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTAC
+
@@@FDDDDFFHHHGIGBEAFAAEFFHIIGGGHGFFHIGGIGCEEGHIHGGIGGH?EHDBBECCCECCAA@CCCCC?CC:@CACCCCC@CCCCCCC@@BCCC
@7LM
GCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATG
+
??;?D:DDD2A:D9CCEE33ABC?FE>B9?EA*1:CBBD;D3:BA9D9DDDDDAADAA/A27?DA>A;@??A2;=>5;3>;AAA>>>A>A?=((39>3>:A
@7LN
TGAAGGCCAGGTGTCCGGAATGCCCAACGACCCAAGCCCCCTGCAAGTGGCTGTGAAGACGCTGCCTGAAGTGTGCTCTGAACAGGACGAACTGGATTTCC
+
?@@FBBDFGGGCFBFHGIIIGHJJIJGHHHGJGGIFDHIJJIFGIJJ@DGFEH6??BDC@>C>@DDACCCC5@>@@>:>ACCDCDBDDDB><?CCA:CCCD
@7LO
CAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTC
+
CCCFFFFFHHHHHGGFHIGGHIJIJJCFHIJJIJJJJJJJJJIIGIJJJIJJFHHIJJJIJIJJIHHHFFFFFEEEEEEDDDDDDDDDDDDDDEDDDDDD
@7LP
CCGAAACCTGACCGGGCCTTCCCAGCTCACCTCCCTCCATCGCAGTCCATACCAGATAGCAGCTACCCCATGGACCACAGATTTCGCCGCCAGCTTTCTG
+
CCCFFFFFHHHHHJGGIGJIJIJEHIGJIJJGIGGCDHCHIBGHE@DHGGHHHHHDDFFEECEEDEDDD=?CCDCDABBBCDDCDDDD9BDBBB>>ACAC
@7LQ
CCTCCCTCCTCTTCCCAATACTATTCCCACTCCTCCAGATGCTCCAAATATCATGCACAAATGAGCAGGGCCGCGGTGGGAGTGGGCGCAGTGCGCTGCTG
+
@@?DDF?EHFA?BBGG<C;FFHEHCCHBBFIGGGBH@9?B9BGC@GHIHI@B9?DECHIIICFGEHEIG@CHDF;>?=;:12<ABB@5<-08:(095<@:>
@7LR
ACCAGTCATGAGCAGGGCTTCTCTGTGGAACTGGAAAGTGAAATTTCAACCACAGCAGATGACTGCAGTTCAGAGGTAAATGGTTGCAGTTTTGTGATG
+
@@@FFDDDFDFHDDDFAGEGGIEEHAAEHGIJIGI@FHI@DBDH<BDFDFBGGIIJJGECHCHGF@DE=EEGEEHF7?@BDDF;AAEEDCDDCAACCDD
@7LS
ATGAGGGTTACCTATGGGACTGAAGGACTGCAGCAGTTACAAGAATTTGAAGCTGCCATTAAACAAAGAGATGGCATTATAACCCAGCTCACTGCTAATTT
+
:=:??B:BCDB:<C<CAE;CEF?F<D;??;@AB<CD9B???DD>D?D9D/B?DDEEDCC>CDEACD@CEIACDDD>AA;?A@A>>@?=AAAAAA>A:AA55
@7LT
AGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGG
+
@@<DFFFFGGHHFGHJGGIJJIIHJIGGGIIJJJJIJJIGFIJEHIGGJGFHGIIIJJGGEGCDDEDHHHHFFDDBDD?CDCDDDCB@DDC?CCDDDDDDD
@7LU
AGCAGCTCATTTCCGGCATGGTTTCGGGTAGCAACAACACCATGGGAACTCCCGGCACCAAACCATCGCCGGCCAAACAGGGCAGCGTGATCAAGGCGGAC
+
5((2>(:@4)).)2=/>=(.()2.):953((7)).=1:<=9(7=;7).()).('5'',9=(((,,(-5(',&&0)62(((++2956&(&((+((((28-0)
@7LV
GGAACCTCCTCCTAAAAAGACGAAGAAAAATAATAGCAGCAACAGCAATGTGAGCAAGAAGGAGCCAGCGCCCATGAAGAGCAAGCCCCCTCCCACGTATG
+
@@@FFADDHFHGHJJIJJIJEGIJIIJJJHIIJIIFIIIJJIIIEHCHGF=CHIGIJIJJIJHHHHFFEBBDDDDDDDCCBCDDDBDDDDBBDDCDDACC?
@7LW
GACAGCACCTACACCTCAGCAGTTACAAGCCTTCAAAAATGAAGTAGGAGTACTCAGGAAAACACGACATGTGAATATCCTACTCTTCATGGGCTATTCC
+
@@@DDDDDFBBFHBHIIIGGEGIBBFHIC?GHHCEHGIGFHABF:BDEGB?BFE?BCEGGDFD;=;AB=B@;@DFDDCC@6@A@CCC@;>AAB?C?AC>@
@7LX
ATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCC
+
;;81BB?B>F>A=EBBA?:AACHBDH>AFDB?CFG@DBFEEFABFEIFEF8C>@?>;;==;5;=@;;@@B<BAB:>@AA@BABAB:AA:::4:AABA@@
@7LY
CCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTC
+
??7B=;===?D>D:?)2@:<AFF@C9C?>EDC9DB?D>BBDBAADE@DD8?BBC@<@CDDD9CDI=2(?;7@?>A>>:A>>>3;>5:>>A:>A5;>,>A<A
@7LZ
CCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTT
+
CCCFFFFFHHGGHJJIJJJJJJJJJJJFGJGJGHIJJJJJJJJJJJIJJJJJJJJJFFFFEEDDDBDDDBBDDDDDDDDDCCDDDDDDD>ACACDCACBC
@7M0
GTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGC
+
@?@DDFFFFHHHDGIIHEIIGGJGIICHIJIJJIJGGH>FEGFFGGEDGGGGIJIEGGIJIJIEHHH3?DFFFFEECCCEDDDD?ACCBDDCCCDBDDB
@7M1
CACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGAT
+
CCCFFFFFHGHHHJJJJJJJJIJJJIJIJJJIJJJJBHGJIIJJJHJJJJIJJIJJIJJJJJHGHHFFFFEDEEDDDDDDDDEEDDCDDDDDDDDBDDDDD
@7M2
CAGGGGAACTAATGGCGTGTTGGTTGAGAATTTAGCTATGCAGGTTAGTGTTGAGGTCTGGGGTGATTTAAAAAAAGTAGAGATATAAATCAAGAGAGGCG
+
00((((((()))2)2(2((-(11((1))10.))0)9):)))))0(0;1<3)).))).).)).--'(.(..((.(,,'((,((((++((+((+5:45((+()
@7M3
CCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATG
+
CCCFFFFFHHHHHJJJJJJJJJJIIIJJJJJHIJJJJJJJJJJFIJJJJJJIJJJJJJIJIJJHHHFFEECEEEEEEECDDDDDDDDDDDDDDDCDDDDED
@7M4
TGGGGCATTCAGAAAAACAGGCCAGCTATGAACTATGATAAACTTAGCCGTTCACTCCGCTATTACTATGAGAAAGGAATTATGCAAAAGGTGAGCAGCT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJIIJJJJJJJJJJJJJJJJJJIJIJJJJJJJJJHHHHHHHHFFFFFEEEEDDDEDCEDDDDD:@CDDDDDD
@7M5
GTCCTATGTACCAACGCCAGATGTCTGAGCCAAACATCCCCTTCCCACCACAAGGCTTTAAGCAGGAGTACCACGACCCAGTGTATGAACACAACACCATG
+
CBCFFFFFHHHHHIJJJJJJJIJJIGIJJIJJJJJJJJJJJJJJJJIJJJJJJJIJJJJJJJHHHHFFEFFEEEDDDDDDDCDCFDEDEDDDDDDDDDDDD
@7M6
CTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGT
+
@@CFDFFDHGHFHJJJGGHGGIGIIGIJIEHICH<FHGHJJJJGGGECFHGGGIGHJGIEHDHIJGHHHEFDDC>?;@@CDCC?BCDDDBBAC:CCCDDDA
@7M7
GAACAAACCAAAGAAAAAGGAGAAAGACAAGAAGGAAAAGAAAAAAGAAAAGCACAAAAGGAAAGAGGAAGTGGAAGAGAATAAAAAAAGCAAAGCCAAGG
+
CCCFFFFBHHHHHJJJJIJJIJJGIIIIJIIIJIIIIJGIGIJJJJJIIJIIIIDEHHHFFFFDD@CB?BD3>C@CC<BCDDDDDDDDD98CDDCDBDCBB
@7M8
CTGAAAATGAGTTTTCTTTAAGGCCAATTGACAGCAACACGTTTGAAATGAATGGCAAAGCTCTCCTGCTGCTGACCAAAGAGGACTTTCGCTATCGATCT
+
CCCFFFFFGHHFHIJJJJJJJJJJJJJJJJJJJJJIJJIJJJJJIJJIJJJJJJJJJJJJJJIJJJJJIJJJHHHHHFFFFEEDEDDDDDDDDDDDDDDDD
@7M9
GACAAATTCAGGCAGTACTCAGCAAGGTACAACTATTCTTCAGTATGCACAGACCTCTGATGGACAGCAGATACTTGTGCCCAGCAATCAGGTGGTCGTAC
+
CCCFFFFFHHHHHJICGGIJJJIIGJJEHHIJIHJJJIIIIJJIJJJJJJJIJJJJJJJJIJJIGHJJJJIJIJIJHGHHHFDFFFEECEDD;CDBCDBDD
@7MA
CACAAACGATCAGTAAGAATACAGAGCAACGGCCCCAGCCAGATCCGTATCAGATCCTGGGCCCGACCAGCAGTCGCCTAGCCAACCCTGGAAGCGGGC
+
;=@ADD?D:BFF?HGEBBHADBFHIAGIIIA:FDHIG=GECGGGIGGHGEGGGGGHHE>;5??AA?>??BB9@>C<9?@@<:?:?BB@@?<BC>B<BB>
@7MB
CAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTG
+
C@@FFFFFHHHFDHGGHIIJGGHIJJJGEIIJIGJJIJJIIG;AFGIGIIJGIEHFGFFFFEDECAEDCCCDBDCDDDDEDDDDEDDEDDCDDDDDDDDDD
@7MC
CCTGGCTCATCCCAGCAGAACAGAAGGCTGTATGTTTGAAAAGGGCCCCAGGCAGTTTTATGATGACACCTGTGTTGTCCCAGAAAAATTCGATGGAGAC
+
??@B?DFDF?A?FHG>CC?A;E@FHDE=GE?EBG:DFG@FFEHIGIGGHIGIGGGGIDDCCCHC:==?EC>B;;CC;6;A@C;=CCABBCCB(;>@CB<8
@7MD
CAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTC
+
@@@FFFDDHHHG?GGGGBCDDHHIIIIBEG?EHGGGFIIHBFEHGIIIHIGCHHGHGEEGGGIGIIFHC?3?C>;AE;@@AC>C@@?CBD9>@B>A>ABCB
@7ME
AGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACA
+
@@@DFDFDDHDCFHIGGGIJJIGGHDGGIGFDF@FDHGHGEEEHEDFAGAHIHFHFFFFFEDC;ACCDDCDD???BDDB<ABBCDDCCACDAA:>:>
@7MF
CCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGAC
+
CCCFFFFFHHHHHJJJJJJJJIJJIJJJJIIJJIJJJJJIJIJJGJJIIJGDGIGHIIGJJIJGIHHGDEEDEFFEEEDDDBBBDDDDDCDCDDEEEDDD
@7MG
CGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCA
+
BC@DFDDFFHHHHJJJIJJJJJJJJJJIJJJJIJJJJJJIJJJJJJJIJJHJIJJHHHHGFDDDDDDDDDDDDDDCDDEDDDDDDDDDDDDDDDDDDDD
@7MH
GGCTTTAAGCAGGAGTACCACGACCCAGTGTATGAACACAACACCATGGTTGGCAGTGCGGCCAGCCAAAGCTTTCCCCCTCCTCTGATGATTAAACAGG
+
C@@DBDFBFHHGHIGAEFHHIIJJJJIEFGCFFFGIGHGGGGBGEGIHIHGGHGIG=CEEBDD?B?BACA?CACCCDCCB<>DDD@A>AAC>BDCCCD??
@7MI
GTCATGCTTATATGGAGCAAAACTACTGTAGAGCCCACACCTGGGAAAGGACCTAAAGGTGTATATCAAATCAGCAAACAAATCAAAGCTCATGATGGC
+
CCCFFFFFHHHHHJJJGIJJJJJJJJIJHHGHHIJGGIIGJIJGEEGGIDIJJJGGHIHHICFDHIIGIIIHECCEDEFFDCCEEEDDCDCCCDCDDDC
@7MJ
CTCAAGTAAGCTCTTTATTAGATGTTGTTGTGAACATGACAAGCAGGGGGGCTGAAGGATCAGTTTCTAAAGTAAATAAAAGTTTTGGTGAAGAATCAAA
+
;(((():9;4=><914)<>?8))=))))3(.2=))@>3339>7>><(-7(5&7:</22:592:(22((+8::(2/:=2:<:/(+4:78(28::(66((+(
@7MK
CGTTATTACTATGATAAAAACATTATGACCAAAGTGCACGGCAAAAGATATGCTTACAAATTTGACTTCCACGGCATTGCCCAGGCTCTGCAGCCACATCC
+
=@:4BBDDBACF?:FG>:<AGF@FF4,ACFF31:*19*:8?@DGDGF1BF</==/8.=FG@CF;@@=@@EEFEA9?@;(.;A;,(55<A355?A?<<@@4>
@7ML
ACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACG
+
CCCFFFFFHHHHDGJGIIIJIFHGGHJIJJHGGGHGGIIIEGIJJJGIJJIGIIIIGIIIJIFHHHBDFFCE>CCCCDDECDCDDDDBDCDCD?BDBCDDD
@7MM
ATTATGCAAAAGGTGGCTGGAGAGAGATATGTCTACAAGTTTGTGTGTGATCCAGAAGCCCTTTTCTCCATGGCCTTTCCAGATAATCAGCGTCCACTGCT
+
CCCFFFFFHHHHGFHIJJJJJJGHGIIJJJJIJJJJJJJIJJJJJGHGIJJJJJJJJIJJJJJJJJJIJJHHHHHFFFFFFECEEDECDDCDBDDDDDDDD
@7MN
GAGATATGTCTACAAGTTTGTGTGTGATCCAGAAGCCCTTTTCTCCATGGCCTTTCCAGATAATCAGCGTCCACTGCTGAAGACAGACATGGAACGTCAC
+
????DDDDFHDB+AFHIB?FAFAFGGHHHFGHGDDFHGIGGIICBFBBFHHIFGGGHII:FBHIGHGEAGGEHHFF@EEC@CE7>>C>BCCC;@CB????
@7MO
CAGGGCCAAAGGAAAGGAGAAAAAGAAAAAGGAAGCAGAGGAAGAGGATGAGGAACTCTCCAACTTTGCTTACCTCTTGGCCTCTAAACTTAGCCTCTCAC
+
CCCFFFFFHHHHHIJJJIJJJJJJIJJJJJJJJJJJJJJIJJJJJJJIIIIIJJIJJJJHHHHHFFFFFFEEEEEEDDDDDDDDDDDDDDDDDDDDDDDDD
@7MP
CAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGG
+
CCCFFFFFHGHHHJJJJJJFHJJJJJJJJIJJJJJJJJJJIJJJIJJJJJJHHHFHHFFFFDDDDDDDDDDEDDDDDDDDDDDDDDDDDDDDDCDCD
@7MQ
CTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACT
+
@BCDFFDFHHHHHJJJIJIIJJJJJJJJJJJJJJJIJJJJIJIIIJJJJIIIJJJIJJJJHHHHHHFFFFFFEDDDDDDDDDDDDDDDDEDEDDDDDDDDC
@7MR
GTCATGATGGTCGAGGTGCGGAGCTTGCTCAGCTTGTACTCAGGGCTCTGCAGCTCCATCTGCATGGCTTGCAGCTCCTGGTGCTTCCGGCGGTACACTGC
+
@@@DDDBDHHHHHIIIC;FGGIIGAFGIGDFFGIEGIGIIGGHGIIGCGI@HCE;@ACEFEFDFFDDCCED@DAC>CCDDD@?ACCA@@BBD@&)0:A@C<
@7MS
CTGGAGACTCAGGTGGAGTCATGCTTATATGGAGCAAAACTACTGTAGAGCCCACACCTGGGAAAGGACCTAAAGGTGTATATCAAATCAGCAAACAAATC
+
@CCFFFFFHHHGHGGGJIHHJJJJJJJJJJJJIIJJJJJJJJIJJJIJJIJJJJJJJJJJJJJIIJJEHHHHFFFF;@@AEEEEEDDDDDDDCDDDDDDDD
@7MT
CCAGAAGCCCTTTTCTCCATGGCCTTTCCAGATAATCAGCGTCCACTGCTGAAGACAGACATGGAACGTCACATCAACGAGGAGGACACAGTGCCTCTTTC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJIJJJJJJHJJJJJIJJJJJJJJJJJJJJJJJJJJJJJHHHHFFFFFDDDDDDDDDDDDDDCDDDDDDDDD
@7MU
CTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTAT
+
@@CFDFDFFHGHGIJJIJGIIGHIJJJIJJJIJJIIJIJJJJJJJJFIIGHIGCHGGIJIJGHIJJIHFFHFCEFFFCEDEDDDCDDDDDDDBBBDDDDDD
@7MV
ATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCC
+
CCCFFFFFHHHHHJJJIJJJJJJJJJJJJIJIJJJJIIJJJJJJJJJIJIHJJJHHHHFFFFDDEDDDDDDDDDDDDDDBCDCDDDEDDDDEDDEDDDD
@7MW
AGGTCATACTGCATCAGAACCATGAAGAAGATAACTGTGTCCAGAGGACCCCCAGGCCATCCGTGGATAATGTGCACCATAACCCTCCCACCATTGAACTG
+
@@CDDFFFGHHHGIIIIEEFHIIJJIGGIJJGIIJIJIIGIIIJIJGIIFGGIJIGIGGHJIJHGFHHFFFFBEEDEEBEEDCDDDDDBCDDDDDDDDDDD
@7MX
TTTAACGAATGGGGTTGTGATGGCCCAGGTTCTTCAAAAGATAGATCCTGCATATTTTGATGAAAATTGGCTAAACAGAATCAAAACTGAAGTAGGAGAT
+
???DD;B=DDDB>;)<@2<4+<?;CED<8??B9?BDDECEI3DDBDEBDCBABCEEIIA5@@C;==CDC@CA<AA;@A@;;@AAAA=>A::>,;,>>A?A
@7MY
CTAAAACAGACACATGGTCCTTTGGAGTGCTGCTATGGGAAATCTTTTTTCTTGGATATATGCCATACCCCAGCAAAAGCAACCAGGAAGTTCTGGAGTTT
+
@CCFDDEFHHHGFHIEICEHGEGIJFHACFEG@GCGHIGIIGHGIIIICHBDHHHGIJGHGGGJFGGGIJGHHFFDDFCACACD@BB?A<CCDACC:A>?C
@7MZ
ATCATCCAGTCACGGGAGCCCTCCCTGAAGAATTCCAACCCCGACGAGATTGAAATCGACTTTGAGACCCTGAAGCCGTCCACACTGCGTGAGCTGGAGCG
+
;?<DDDADFHB<D@BA6E>CEGBFHEBFHCGFH@99BFEHEGB<@F<B<EEECCEDA=>>?@C>@B?CBBCC?@CC@B9@<?@>?CCCB-9<BC>?<??CB
@7N0
CTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJGHIJJJJJHJJGHJJJJHHHHHHFFFFFDEDEEDDDDEDDDDDDDDDDDDDDDDDDDDDDDDEDDD
@7N1
GGGAGCTGCTGAAAGTATTTTGGTCTTCTGGAGACACGGGACAAGGCTTGCAGCCAATTTACTGGAGCAGGGATGACGTAGCCCAGTGGCTCAAGTGGGCT
+
CCCFFFFFHHHHHJJEHIJJJJJGIGJJJJJJJJJJJJJIJJJJIIJJJJJJJIIJJJJJHHHHHHFFFFDDACDDDD?ABBDDDDCDDBBDDDDCCDDDD
@7N2
CAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGG
+
@@CFFFFFHGHFHGGIJJJJEFHIIIEEHGGHGIGIJGIDGGIIIJI@;F7@DEHIFHFHHF>CCDFFC@@CECDDDDDBDBCC@A??ABDD?8?BDACC
@7N3
AAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTAC
+
CCCFFFFFHHHHHJJIIJJJIJJJJJJJJJJJJJJJJJJJJJJJJHHIJJIJJHHHHFFFFDEEEDDDDDDDDCDDDDCCDDEDDDDDDDEDDDDDDCCDD
@7N4
CCACGACCCAGTGTATGAACACAACACCATGGTTGGCAGTGCGGCCAGCCAAAGCTTTCCCCCTCCTCTGATGATTAAACAGGAACCCAGAGATTTTGCAT
+
CCCFFFFFHHHHHCGIJJJJJJJJJIJJJJJJFBFIIIIGGIJJJJJJIHHHFFFFFFEEEEDBDDDDDDDEDEFEDDDDCDDBDDDDDDDDCCDDDDCDD
@7N5
ATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCC
+
CC@FFDEFHGGHHGGBHGJJJFGDG?CGIHIIJJIICHGIGIIIHII@<EGGFFEHEFBBCFECEC>ACDD>CDDBDC@CCDDCDDCDDDDDD?BBBABDD
@7N6
GGGCAGCAGATAGTGCAAATGAAACAAGAATTAATAAGACAACACATGGCACAGATGGAGGAAATGAAAACACGGCATAAGGGAGAAATGGAGAATGCTTT
+
1+114@1=<22<D2<:<2<F@@EF3<<9<F@BE?E@D9::?:D@??DA?D88?B?8=B8=(-.=@;77@C;6=?9<<9;>355583<>:>5(5(<::>::A
@7N7
CAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATG
+
CCCFFFFFHHHHHJJIJJJIJJIJJJIIJJIJJJJJJJJJJJJJJJJJJJJJIJJIJJJJJJJJJJJHHHHFFDDDDDDDDDDDDDDDDDDDDDDDDDEDD
@7N8
CCAGCTATGAACTATGATAAACTTAGCCGTTCACTCCGCTATTACTATGAGAAAGGAATTATGCAAAGGTGGCTGGAGAGAGATATGTCTACAAGTTTGTG
+
@@@DDDDFFGFHHJJJEIGGGJJJIHCHGFEEGEHIEIEHEDHHHIIIH>FEHHHIJJIIGGIEIJGHJ@@EEHHD?BACCDDACDCEEEEDDCC5@CCBC
@7N9
CCTAGTAATAACTACGTGACCCATACCCCTCACAATGATGGCAAGCCAACGCCACGGAGCGAGAGCACCACTATCACGAAATAAACTCTACCTCTCTAGAC
+
0---(2)))29@?;:1>9>;1(.)=)2)8(19())12):)).)95.;)<(75/=3'''''','',((,(((,72282(858((+2(+6/(+((22((((++
@7NA
AGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACC
+
88?:+A2B+<:<8+A<EC4<A?ABCFFCEACDD@DDEIDE@CDDDDDICCCI@DAEEEA>CCD=ADCDC??D?66@AA;>AAAAAA>AAA>=7=9=A>>><
@7NB
CGTCACATCAACGAGGAGGACACAGTGCCTCTTTCTCACTTTGATGAGAGCATGGCCTACATGCCGGAAGGGGGCTGCTGCAACCCCCACCCCTACAACG
+
@@@FFFFFHHHHGHGIFHJGIIIIGEHIJJJJJJJJJIIGIIJIJJJIGJIJIIJIIJIJHIEIIHHFFDDDDDDDDDCDCDDCDDDD<BDDDDBDDDDD
@7NC
TGTTGCACCGCTCCAGGTCACCTATCACGACAAATCACCGGCCTTCTCCTGACCCCGAGCAGCGGCCCCTCCGGTCCCCCCTGGACAACATGATCCGCCGC
+
;;=D???BC?8?DAAEFIEEI?GDB?FEC18@DFF99D;?F<@;CCDD@=C?CAABB<>BBBB=B/;;78;?B909B2?>93<?<@B?B<?>A@AB?7?9@
@7ND
CTATGAGAAAGGAATTATGCAAAAGGTGGCTGGAGAGAGATATGTCTACAAGTTTGTGTGTGATCCAGAAGCCCTTTTCTCCATGGCCTTTCCAGATAATC
+
@@@DDDADDHHGHFHGIGCHEGDCDHFFCGIIF@BAG<GGCIGG9DHIDHIIHIGGFGIGCHCFCDGHIIAEHHHFFFCEDCCEECDCCCCDDACDDDCC:
@7NE
GCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTC
+
;@@DDDDDH<C8CCGEGCE8EFEG<**?B<D0?6@<<C()B3CG/=>ADGA4=D?>E>CEE?@>@>;@ACDCA(;;=?<@?@B98<?CB<?:>ACDAC3>
@7NF
TCAAAACTGAAGTAGGAGATAATTGGAGGCTAAAGATAAGCAATTTAAAGAAAATTTTAAAAGGAATCTTGGATTATAATCATGAGATTTTAGGACAGCA
+
@@@DBDEFFFABF@EGGGC@HCHGIGCHEGHHIEH@DEB@ADBFGBD@GEHIEBFCEHGCHGII;@;CGHG@DGGEHHHHFGFEFFBEEAE>@ACCDDDD
@7NG
CTTCAGCTCTGGCAGTTTTTGGTAGCTCTTCTGGATGACCCTTCAAATTCTCATTTTATTGCCTGGACTGGTCGAGGCATGGAATTTAAACTGATTGAGCC
+
CCCFFFFFHHHHHJJHIJJJJJHIJIIJJJJJJJIJJJJJJJJJJJJIJGIJIJJJJJJJJJIIIJGIJJJIJHHFFDDEDDDDDDDDEDDDDDDDDCCDD
@7NH
TGTTTCTGCATCTGAATCCAGAAAGGAACTAGAATTAAAACATGAAGCAGAAGTTACAAATTACAAGATAAAACTTGAAATGTTAGAAAAAGAAAAGAATG
+
:=?DBDD842ACDEEBCEBCFB;EEEFE;FFAEEEEECF<?BDDEIDDDDIECBADDECD@CDACDBC;CECCCADAAC;A?7ADA;ADDA<>A??;??>:
@7NI
CCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGT
+
@@@DDDA?DDFB<CFGGIDH?CGFDGGIGBFFGHIIIIG@C@;@@FDD;CGGHA?CHHCC@DA@ADCFCC??@@A3:;ABB?8@BCAC@B899?CC4828:
@7NJ
CTCTGTCTATGTTCTTGCTGTTCGCCCCCGACCCCGCAGAGCCTTCGTTAAGGGTTATTGATAGAAATAATAACCCCATGCTTATCAACCGTCGTTGGATG
+
000((268))).92)<).<)).)(((((1((((((0''--6).)..(.).,).(6(((((((((((,3;52(,;((0(((((+/((+((+0+&&)&+(3((
@7NK
CTTCTGAAGAAATAAAACAGTTAATGGGGACAGTCGAAGAACTTCAGAAGAGAAATCATAAAGACAGCCAGTTCGAAACTGATATAGTACAACGAATGGA
+
@@@DDDDBDCFFFHJJIIIIBHGHHHDGG?@GIJJJIGIIIGIIADDFHGGDHIIEACHHIJCFAGCCAHCECEBDDDACCCCCCDDCFEDD>?BD<C@C
@7NL
TAAAAGCTAATCTCTCCATTCATTGCCCCCACAATCATAGGACTACCCGCCGCAGTACTGATCATTCTATTTCCCCCTCTATTGATCCCCACCACCAAAT
+
(;3;5)(.)))))..))<)))3)))34@;=??><)))1>3.)00.<??==5-=9'(.)6=)).6;;)69=;==1=(5;<<;50(,2(,(,89-+2:6986
@7NM
CACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGAT
+
CCCFFFFFHHHHHJJJIJJJJJJJJJJJJJJJJJJJGIJJJJJJJFHHIJJJJIJJJJJJJJHHHHFFFFEDCEDDDDDDDDEEDDDDDDDDDDDBDDDCD
@7NN
CTGAGACATTCTTCTGATAAAGTATCTAAACTAGAAGGTCAAGTAGAATCTTATAAAAAGAAGCTAGAAGACCTTGGTGATTTAAGGCGGCAGGTTAAACT
+
CCCFFFFFHHHHHJJJJJJJJJIJIJJIJJJIIIIJIIGIJJJHGHJJJJIJJJJJJJIJJJIIJJIJJGIJJJJJICHHHHHHHHFFFDDDDDBDDDDCC
@7NO
CTTCTCCCCAGCCCTCTTCACAACCTCTCCAAATACACAGACAAACTCCAGAAAGCAAGAATGCTACTCCCACCAAAAGCATAAAACGACCATCACCAGCT
+
@CCFFFDFHHGHHJGGIJJJIJJJJGGJJIJJJIJJJJJJJJJJJJJJJJGIGIIIJJJIJJJJIJIHHHHHFFFDDDEEDDDDDDDBDDDDDDDCDDDDD
@7NP
TGTGATTCCTGAATCTACAATAATGAGAACTCTACATAGTGGAGAAATAACCAGTCATGAGCAGGGCTTCTCTGTGGAACTGGAAAGTGAAATTTCAACC
+
@CBFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJIIJJIIJJJJJJJJJIJJJJJJJJJJJJJJJJJJJGIJHHHHHFFFFFCCEEEEEDDEDDD
@7NQ
GCACCTCCATCCTACCCTCCTACCAGCTCTTCCTCTACACAGCCGACTAGTTATGACCAGAGCAGTTACTCTCAGCACAACACCTATGGCCAACCGAGC
+
++:+2+<AA@B3AB77?<<+?9=CACBB*117@:?>A4:?A?)94)77'.))8=;A)8)=667>A>A7>>@>9>;>>(;5;;1;;>5:9(,5;;5055;
@7NR
AACAGGGACCAGATAATTTTTTTGGTGGGGAGAGGATACCTGTCTCCAGATCTCCGTAAGGGACGGGGTAACTGTCCAAAAACCATTAAGAGATTTATGGG
+
;<;13?@(9=>88);=4=@?@(<(<(7=?((-'-;3..);)).)..:..6)33.)'(.3(5((,,8'0&)8((++(6(8<<(&8(+((4(+++(8(4+(5(
@7NS
CGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCA
+
B@@DDDFFFHHFDIIJJJJGHIJHIIIIJIJIJIJJJJJJIIIJJJJIJIJJIFIFHHGHFDDDBDDDBDDDDDDCCDEDDDDDD>BDDDBDDCBBBDD
@7NT
CCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTC
+
CCCFFFFFHFFHHIJJ@FGHIIJJIJICFHGIJJJIIJJJJIJJJJJIIJJJJIIIJIIJJIIIJHFHFFDBDDDDEEEDDDDDDD@CDDDDDDEDDDDDD
@7NU
TGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAAT
+
??<;BDDBDAFH?DGI?AIICAFGGGHII@FG@>FBGFD;FBDH@9BGEEIGCBHGD=@FDHGGGHHH?EBEBCCC@ACC@CCCAB<<ABCCCCCA:>CCC
@7NV
ACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCT
+
@@CFDDFFGHHFFGHGGBGFBHIFICHJFHHIFIIIGCFGGEHIIIJJ?DHIGHIIGHIJJJJIJJFHHHGFFFFFEEEEEDCDDDDDDDDDDDDDDCDDD
@7NW
GCAAGAGAAAGAACAAGTTTCATTGAGATGTAGAGAGCTAGAAATCATTATTAACCACAACAGGGCAGAAAATGTACAGTCATGTGATACTCAAGTAAGCT
+
@@<DDDDDBDFABDCFECBDEHGEGIIIIE?E>GCHIIEHIBGGGDCGIGEHIGHIIIBHGIIIIIIIIIHEFE=ACEEDDEDEDCDDDCAACCC@>A>CC
@7NX
CTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTAT
+
CCCFFFFFHHHHHJJJJJJJJIJJJJJJJIJJJJJJJJJJJFHJJJJJJJJHHHHHHFFFFFFEEEEDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDCDD
@7NY
CAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGC
+
C@CDFFFFHHHHHIJJJJIGIGJJJJIJJJJJJIGHIGGGIGIFGGIIJGIHHHEHFHDBEC@DDDBEACDCCDCDDDDDCBBBDDDBBDBBDBDDDDDD
@7NZ
GGACAGCAGATACTTGTGCCCAGCAATCAGGTGGTCGTACAAACTGCATCAGGAGATATGCAAACATATCAGAACCGAACTACACCTTCAGCTACTTCTCT
+
CCCFFFFFGHHHHJJJHIJJJJJJJJJJJJJGHIHIJHIIJJJJJJIJJIJJIJIJJIJJIJJJJJJHHHHHHFFFDDDDDDDDDDDDDDDDDDDDDDDDD
@7O0
CGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCT
+
CCCFFFFFHGDHFIJJJFHIJIHHHIJHIJIF>GHIIJJJGCGIJJJJIJJJIIGGGGIIJJJJGIHHHHHHFFFFDDBDBDDDDCDDDDDDDCDDDDDBC
@7O1
CTGTGTTGTCCCAGAAAAATTCGATGGAGACATCAAACAAGAGCCAGGAATGTATCGGGAAGGACCCACATACCAACGGCGAGGATCACTTCAGCTCTGGC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIIJIJJJJJJJHHHFFFFDEEEEDDDDDCDDDDDDDDDDDDDDDDDDDDC
@7O2
CTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGC
+
CCCFFFFFHHHHHJJJJJJJIJJJJJJJJJJJJJJJJJJJJJIJJJJJJIJIJJJJJJJJJJJJJHHHHFFFFFFEEEECEDDDDDDDDDDDDDDDDDDD
@7O3
GTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGC
+
@<@DDDDDAFHD>DH?GHBHGDHGH@:BFAGHGE8DFGG;CAE7787CH;@D;7=;ACDCC@B>@A>6>5>CCCBCBB>@CC;A?<18>?>@C@B8<AC
@7O4
CTCACCTCTCAGACAACTAAGACAGATGACCCCCAATTGAAAAGAGAAATAAGGTTAATGAAAAACAGAGAAGCTGCTCGAGAATGTCGCAGAAAGAAGA
+
C@CFFFFDHHGHHJIJGHIJIJJJJEHJJJJIJJJIHGIGGHIIEGIGJIJJJJGHGGGEHJJIJIIHHHHFFFFFFEEDBDDDDDDDDDDDDDDDCBCD
@7O5
TTTGGAACAGTCTACAAGGGAAAGTGGCATGGTGATGTGGCAGTGAAAATGTTGAATGTGACAGCACCTACACCTCAGCAGTTACAAGCCTTCAAAAATG
+
@CCFFDDFGFHHHIJJJGIJEHIIAEEHHIIJ?FGHGDHDIJGDFGIIIIIIJJDGCGCBHGGGIGIIEHADEECEE>BCDCEEDEECBDDDDDDDDDBC
@7O6
CTGTTACTCTATCCACACTGCAGATTATTGGACTTGGCACTTTTGAGCGTGGAGTAGGATGCCTGGATTTTTCAAAAGCAGATTCAGGTGTTCATTTATGT
+
@CCDDFFFHGHHHJJJIJJJJJJJIJIJJJJIIIJJJJJJJJJJJHJJIGHIIIFHIIGIJFIJJJIIHHHHHHFFFFFEEEEEEDCC@CCBDDEEDEFDD
@7O7
TGGGCAACCGAGCAGCTATGGACAGCAGAGGAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTAC
+
@?@DADDDBF@?FEG?AEFFHHE?EH9?F@)?DFDHIEG8?BDBFHIGC@=;FFHIGFIH8E6;;;;@BC>2=CCCE>@@C>BBBBB?<14@A>C><CAC
@7O8
CCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGCACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCT
+
11=+A;B;=DC?DDFIF9B<<@BF;++2?C9*:?DG??*?9??BDDD)8(/?DFF9-'8;=AEE;C<AE>)?B9>3>A665>5>-;<9>>?>@B@BA?@3
@7O9
CAGTTACCTTATTCAAACATCAACAACAGGGACCAGATAATTTTTATGGTGGGACGAGGATACCTGTCTCCAGATCTCAGTAAGGAACGGGGTAACTGTCC
+
7-;(:4.:8:>@9).@@><9=8<<???77(2(((=3??;8:>:?=<>87.)(-..5'5;'.;=>86))..:=(687136=(-(98(2327'&))36:;2:5
@7OA
CGGAGGAACCCTTGAGGAATTGTGTAGGAAGCCAGGTAGGCCACAGAGACGGATTGCGGAGGGTGATGCGGAAGGACTCGACAGGGATTGGGGAATGGATG
+
(07::-<3(2-()))2):64)8.223)).228(<(3))0(<>19><11).(555'))'-,,3'9;;37(8;'5)+68:/(68&082(((+++5(&(++((5
@7OB
TTCAAATATTACAGTTAATGAAGATCAGATAAAGTTAATGAATGTGGCAATAAATGAACTGAATATAAAATTGCAAGATACTAACTCTCAAAAGGAAAAAC
+
CCCFFFFFHHHHHJIJJJIJGHIIIJJJJJJJJJIJJJJJJIJJGIJJJJIJJJJJJJJJJJJJJHJJJJJJJJJJIIGIGIIJJHHHHHHFFFFEEEEEB
@7OC
ATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCT
+
CCCFFFFFGHHHDHIJJJJJJJJJJJJJJJJJFHIIIJJJEIJJJJJJJJJJJJJJJJJHJJJJJJJJHHHHHFFFFFEEECDDDDDDDDDDDDDEEDDD
@7OD
CCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACT
+
CCCFFFFFHHHHHJJJJJJJJJIJJHIIJIIJJJJJJJIJIIJIJJJJJJJIHJJJIJIIIJJJJIJIHHHHHGFFFEFEEDEDDDDDDDDBDBDBDDDCD
@7OE
GCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACT
+
CCCFFFFFHHHHGJJIJEHIJJJJJIJJEFHJJJJJHHGIJIJJJJJJJJJJJJIJJJJJJJIJJHHHFFFFEDEEEEDEDDDDCDDDDDDDDDDEDDDDD
@7OF
AGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAAC
+
@CCFFFD;FHFHFIIFGHEHIIIIIIIGIGCGGIIIIIIGIIIIIIGGHGGGGIIIFFEHIEIAHHEEEHFEB?CDDECCCAEC?CCDDDDCC@A>ABCDD
@7OG
CTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTAT
+
CCCFFFFFHHHHHIJJIJIJIJJJJJJJJIJJJJJJIJJJJFHGIJGJJJIHAEHGHFFFFFFEEEEDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDD
@7OH
CAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTTATGGGCAGG
+
@@@DDDBD?<B>FH@GGICIGGGGEDGGGICHGCHIBGGIGCHHDHIEB==@AEFDE@DE>@EFFBDDCD?ADDBBDDCC:CDEDDD9<9BCA>CABBC@B
@7OI
GCTGCGCGGGCCCCCGGATCCCCCGACAGAGCGGCGGCGGTGTCTGGCCAGGCGGTAGGCGCTGCCCGGCCGCGGGGGGGGAGGGGTTCAGGGTAGAGGCC
+
@@@FFFF<DHHDHGIBFEGGIJJJE>DCDCCDDB@B66@:-533(8<AB(8?<59)0)83)5&&)8()509&&09&0<BB&)5&&&&0+(+((((++4(((
@7OJ
TAACTGTCCAAAAGCCATGAAGAGATTAATGGCAGAGTGCCTCAAAAAGAAAAGAGATGAGAGACCACTCTTTCCCCAAATTCTCGCCTCTATTGAGCTGC
+
CCCFFFFFHHGHHIBHIIIJIHDHIGEGIE<B@E??C?DCGGIIIIJIIJJJFIIJDHEGGFCGHHEGHBCEEHFFFFDEDEA>CBD@DBDCCACDCDCDD
@7OK
AGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACC
+
@@?DD>BDFFF6CGI9EEEFFEBAFFFIIIIEDBGGFFGIIIIIEFIIIIFEFFEB@@@DC;@AAAAABBB@:=:<?BBBB??BB?BBBBBBBBAB>?91<
@7OL
AATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCC
+
555(2(8--0-.(-(<36@369@@@93.=>????75::3:6>3=3/9:(=/=669336=89.9=8995;<557,6:<8<766;6</6626(::+++8</2:
@7OM
AGGATGCCTCCTCCTTGCCTGAAGCCAGTCAAGAGGCAGGGAGCAGAGGCAATTCCTTTTCTCCTCTGTTGGAAACCATAGAACCTGTCAACATACT
+
?@;?=AAA?CDDCF:CBCDCE@C:<8<<<CE>G@DGIBDFI<?FFD@=B6C=FCGDEDA===??3?ED;B>B>;A>A6;55;;@?<@>:ADB@@>:A
@7ON
CAGCAATCAGGTGGTCGTACAAACTGCATCAGGAGATATGCAAACATATCAGATCCGAACTACACCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATG
+
@@@DDFDDHFFCFHFGHFFHIJJFGGIJJEIIIJIIIGIGEGHDHIIJGGIIHIIIIGEIJJJIHHFHHFFFFFFECECECCDCDDBDDBCDCCD??CCC
@7OO
CACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCA
+
@@@FFDDDFFHBDHGGEEHIG?HIIIIGIJJIIIIEGIJEHFII9DDGIIJJIEEHEGIIHG>EHHFFFFFFECEDDDDDDDDBADDCD@CDCDACA>CC
@7OP
GCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACC
+
@@@DBDDFHHHHBHGGIECBHHG@HEHGGDGIGIEIGIEE@GHCFIIBFGIGFFHIIIIIIIGIGHGHHFFFFCEECCCEAACCCDCCCCCBBBBCCCCC
@7OQ
CAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTG
+
@@@DDDDDHHHFHIJIJHGIJJIJIICGGGHGIJJJIIIGGCHIJJEHHGIJIEICGHHHGFEFFFEEDCEDDDCDDDDDDDDDDDDDDDDDDDDDBDDD
@7OR
CTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGC
+
CCCFFFFFHHGHHJJJIJJJJJIJJJJJJIJJJIIJJJJJJIJJIJJJIIJIJJJJJIIIJJJJJHGHHFFFDEFEEEECEEDDDDDDDDCDDDDDDDDD
@7OS
CCTCCAACCCCCCCACACCATCCAGCACGCCAGTGTCCCCACTGCATCATGCATCTCCAAACTCAACTCATACACCGAAACCTGACCGGGCCTTCCCAGCT
+
C@@FFFFFHHHHHIIJJJJJJJJJJJGIDBHGIFEGHHGIIHHGHHFFFFFFEEDEEEDDDDDDDDDDDACDDDDDDDDDDDCDDDDDDBDDDDDDDDDDD
@7OT
ATAAAATTAGCCAGGTTTGGGGATAATCAAAAGAATGCGGAGCTCAAAGGGGGGCCGAAATGTGAGGATTGTTAGAGCGCGGCTACATCAAGAAGGCAG
+
8(02(2))2).4)(()).(3-((())))2)=)297)).0((743.)))).(':&&&&&&&+3+(+(+(+2(++((+4(&&)))&((((+(++(+(((+(
@7OU
GGTAGCTCTTCTGGATGACCCTTCAAATTCTCATTTTATTGCCTGGACTGGTCGAGGCATGGAATTTAAACTGATTGAGCCTGAAGAGGTGGCCCGACGTT
+
@@BFDFFFHHHHHIIJJJIJJIJJJJJIJJJIJJJJJJJJJJJJJJIJJIJDHIJJJJIJJJJIJJJHHHHHHFFFFFFEEEDEDDDDD>ABDDDBDDD9@
@7OV
CTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCT
+
@@@?D;DDBFHHDGHGGGIIII>FHIIIIGGIBB?BACGF@EBDFHGIGE;CGEHIII@EHIHHHEDBD>>ACCBB>C5>ACCCCBBBBBBB@CCCCCC<>
@7OW
ATTTTAACTCTTGGTCATCAGCCTTATCCAGCTCATTCCAACCTTGATGTGTTAAACTATGTGCAAACAGGAGGGAGACTGGAGCCACCAAGAAATTGTCC
+
CCCFFFFFHHHHHJFHIIGIGHJIIJIJJGIGIJJJJGHGICHIJGGIJJJJJGIJHJHIGBHIJIJIIJJIJFF<EBFDFFECECCCBDDBBCCDCDDDD
@7OX
CCAAGGGAAGGACGTCCTATGTACCAACGCCAGATGTCTGAGCCAAACATCCCCTTCCCACCACAAGGCTTTAAGCAGGAGTACCACGACCCAGTGTATG
+
CCCFFFFFHHHHHJIJJJJJJIHJJJJJJJJJJJIJIIJJJJJJJJJJIJJJJJJIJHHHHFFFFDEDDDDDDDDDDDDDD?CDDDDDDDDDDDCCCDEE
@7OY
AGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGC
+
@<@DDDABHA?FBHHEDGGGHH@C@EE@=FB??FHGIE=3BGGGIIEEGGHIIEFHCACFF6;@C=@DHGCHH;@?CFC9>ACCCBBCBBB?B<5<@CCC
@7OZ
CCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGT
+
:=8DD:2+2CC:DC?CE@EF4333A<F?AEE4???1::?>3D<?9BD?*B<39===8BD@DIC;.'',,=AA3(5;;A3;A>A>>>>>=?<9<8<>8<4<(
@7P0
TGATTATCGAATACGTTGTGAAGAGTTAGAAAAGGAGATCTCTGAACTTCGGCAACAGAATGATGAACTGACCACTTTGGCAGATGAAGC
+
:;:B?D?:2=+AACGGA9<AF@HEI92<9:?@B?;3:)0:BG<4<?G?@BFIEBAFC@FE@;E:=DAE37?=;@B;>>AA:.=;ABA;55
@7P1
GCTCCTCGGACAGTGACAGTTCGACTGATGACTCTGAGGAGGAGCGAGCCCAGCGGCTGGCTGAGCTCCAGGAGCAGCTCAAAGCCGAGCACGAGCAGCTT
+
??@B1B3?@F:??F<F<F9H@E;FGFEGB<9?<9?0::?9?6((0--@@;@E=EBB'',/8?<9(((,,:(3(+((++((++4(<?-&00585<5.5?89+
@7P2
AGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACT
+
CCCFFFFFHHHHHJJJJJJJGJJJJJJJJJJJJJJJJJJJHJJJJJJJJGGIIJJJJJJJJHHHHHHFFFDCEEEDDDDDDDDDDDEEDDDDDDDDDDDDD
@7P3
CGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCC
+
@@@DDFFDHHHHHFHIHGGHIHIHIIJIGIJJJJGJIJJIJJJIIJJJHHHHHHFFFFFFEEECDDDDCDDDDDDDDDDDDBDDDDBCDEDDDDDDDDDD
@7P4
TGCAAGATACTAACTCTCAAAAGGAAAAACTCAAGGAAGAACTAGGACTAATTTTAGAAGAAAAGTGTGCTCTACAGAGACAGCTTGAAGACCTTGTTGA
+
;@?D?B?BFHDH<?FBEBFBHI;GECHIIIA9EHB>8D?0::DGD?GBGFDCB@D?B=<B=FAHIHE;@;7==?EHHCCBDB;;C@;;>;>>;5;:5>?5
@7P5
CACATACCAACGGCGAGGATCACTTCAGCTCTGGCAGTTTTTGGTAGCTCTTCTGGATGACCCTTCAAATTCTCATTTTATTGCCTGGACTGGTCGAGGC
+
?<@DFDDBAFDHHIBHGIIEHEEGGGHIDFGGHAB@FCEGCHIA@A=A>EHH?@D@;;>@@ABCCCACCCCCCC:;ADDECCCCAC@?1<CBA::53555
@7P6
CAAGCCTTCAAAAATGAAGTAGGAGTACTCAGGAAAACACGACATGTGAATATCCTACTCTTCATGGGCTATTCCACAAAGCCACAACTGGCTATTGTTAC
+
CCCFFFFFHHHHHJJJJJJIJJJJJHIJJJJJJJJJJJJJJIJJJJIIJJJJJJJJJJIJIJJJJJJJJHHHHHHFFFFFEEEDDDDDDDDDDDDDDEDDD
@7P7
CAAGAACAGATTGTGCAAAAGAACCAAGAAATAAAAAACATGAAATTAGAGCTGACTAATTCTAAGCAAAAAGAAAGACAGTCTTCTGAAGAAATAAAAC
+
CCCFFFFFHHHHHGHHIIJJIJJJJJJJIJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJIJHHHHFFFFDEEEEDDDEDDDEDDDDDDDDDDD
@7P8
CACACAGGTCAGCAGACAGGGCCAAAGGAAAGGAGAAAAAGAAAAAGGAAGCAGAGGAAGAGGATGAGGAACTCTCCAACTTTGCTTACCTCTTGGCCTCT
+
@<@FDDDDHBHHDGHIDGBCDA@GHIIIIIIIGIIIIGIIEIIEGII=HC=FHG@DDEHG>CB>>@C@C>AACCCCCCCC?@CAA@CCCACCCCCCCCC<C
@7P9
CAAGAAAGAACCCCACAGTCCATGTTCAGAAATCAGCTCTGCCTGCAGTCAAGAACAGCCCTTTAAATTCAGCTATGGAGAAAAGTGCCTGTACAATGTC
+
CCCFFFFFHHHHHJJJJJHIJJJJIIJJJJJJJJJJJJJJJJJJJJJJIIJJJJJIJJJJJJJJJJJJJHHHHHHHFFDFFEEEEACDDDDCDDFDDDDE
@7PA
AAGCAGTAAACATGATGTGTCAGCACACCATGATTTGAATATTGATCAATCACAGTGTAATGAAATGTACATAAATAGTTCTCAGAGAGTAGAATCAACTG
+
CCCFFFFFHHHHHJJJIHIJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJHIIJIJJIJIJJFHIIGIJJJJJHIGIIJJJHHG=BDFFFFFEEED
@7PB
CCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCT
+
@@@DFFFFHHGHGIJJIIJJJJJGIGIGHJJGIJGIIGGIIJJJJCGIIJJIIIJJIIJJHGHFFFFEEEDDDD?BC@@CDDDDDD9>CDCDDDDDB@ACD
@7PC
AGGAGATATGCAAACATATCAGATCCGAACTACACCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATGACATCTCCTGTGACTCTCACCTCTCAGACA
+
@@@DADFFHHHHHJJEHIIIGGIGIJJICHJJJJJJIIIIHGIIIIGIJGHIJIIGIJJJJJCFG=@E>CC=EHFEFFEE>DCEEE;ACDDCBCDDCDDD
@7PD
TTTGAAGTTAACTATCAAGAGTTACAAGAGGAGTATGCTTGCCTTCTCAAAGTAAAAGATGATTTAGAAGACAGTAAAAATAAACAGGAATTAGAGTATA
+
=?=DD?A=CC?A:?EAA????I@EE?ACGHD?EH@1??GD38?BBDB:9??B0?998?F<88=FFCD:C;@FC@).=@=>E7=7=;;;D;;@C>;@(;;>
@7PE
CAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCC
+
CCCFFFFFGHHHGJJIIIIIGGIIIJIJJJJJJJIDHHIJIJJGGIJGHJJIJJJJJIJHGHHHHFFFFEECEEDEDDDDDDDDDBDDDDDDDDDDDDDD
@7PF
ACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGT
+
@CCFFFFFGHHHHJJJIJJJJJIJJJJIGIJJJJJJIHIIIJGIGIIJJIJIJGJJIIJHHHHFFD?BDDDDDDDDDDDDDCDDDDDDDCDDDDDDDDDC
@7PG
CAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHIJJJJJJJJIHHHHFFFFEEEEDEDDDDDDDDDDDDEDDDDFDDEDDDDDDDCCDDDD
@7PH
TTTGTGTGTGATCCAGAAGCCCTTTTCTCCATGGCCTTTCCAGATAATCAGCGTCCACTGCTGAAGACAGACATGGAACGTCACATCAACGAG
+
CCCFFFFFFDHHHJJJJJJIJJJIIJJJIJJJJIHIJIJJJJIGIIJJHHJIGIJJJJIJGIJIJJJIIJHHHHHFFFFDBDDDDDDDDDDBD
@7PI
CCACATACCAACGGCGAGGATCACTTCAGCTCTGGCAGTTTTTGGTAGCTCTTCTGGATGACCCTTCAAATTCTCATTTTATTGCCTGGACTGGTCGAGGC
+
;=?DDADDFFBFBEGEH<FHEG?DDGHH<FHG9<B3CF)=C>FHIHHFHAEDDD;3;@>6@>>BCCCCCC>5(;3(5>BDCCCACC>C<?8ABB:><995>
@7PJ
GGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCAC
+
@CCFFDFFHHHGHIGIGIIJJIJJJEHIIGIJIIJJJIIJIJIIIIEGGIJJJJGIIJIIIIIIGIIEHFDDDBACDEDDDDDDDDDDCCDC<?B?CDBCA
@7PK
CAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGC
+
@@@;ADDDHHDADDGGGHHHAFHH;CF?CGGCFHIHICBDBHCHEEE<GIEGEHIEDFCDEGGDGD>EHFHEEEEBCCBB?CBBCCCCCD@C?>C?>>C3>
@7PL
GGAGGAGGGAAAGACAGAAAAATAATTCTGTGGGATCATGATCTGAATCCTGAAAGAGAAATAGAGGTTCCTGATCAGTATGGCACAATCAGAGCTGTAGC
+
BCBFFDFFHHHHHJJJJJJJJJJJJJJJJJIIJJJJJIJJIJJJJIJJJJJJIIJJIJIIJIIJJJIHHHHHFFFFFFEEEEEDDDDDDDDDDDDDDDDDD
@7PM
GGGAAAGCGAGAGGGAGACGGACGTTGAGAGAACGAGGAGGGAGGAGAGAAACTGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGG
+
7+7?1A+A?C7)<7802)<;AA0?4;;=ABB1>7:A6/;(;'',5;1((,-5(-((5,3/&8;85;-88??(+5(88:??83(+(89=:==?3&)00.8(8
@7PN
CAAACATCAACAACAGGGACCAGGTGCTTTGTCCTCCATGGGAGTATAATAAATGATGTGGCAAGGGCTTACTCTCCATGAGAGGAATGTGTGACCAAC
+
@??DD?BDHHHHFHID;?CGHCEBA??BBFGDDDCC???B?DB;099BFBGCBBG@@DBCFAFIIIIIEHFHEDEBE>CCCC>A;A;@@>;C?CCCCB?
@7PO
CTATGATAAACTTAGCCGTTCACTCCGCTATTACTATGAGAAAGGAATTATGCAAAAGGTGGCTGGAGAGAGATATGTCTACAAGTTTGTGTGTGATCC
+
CCCFFFFFHHHHHJIJJJJJJIJJJJJJJJJJJJIJJIJJJJJJIJJJJIJJJJJJJJJFGGJIJJDHGHFFFFEEEFDEEDDDDCDDD?CCBABDEDD
@7PP
CATACAGACTGTGTGAAATGCCTTGCTATACATCCTGACAAAATTAGGATTGCAACTGGACAGATAGCTGGCGTGGATAAAGATGGAAGGGTGAGTGGCAT
+
@<?DDB>BFDB<CGEEHFEGGGGHGGIDGHBHGIIFGEEFDFGFHGIE<G<DDHIGIIIGGICHGIGGCHGIG:ABEECCC>CCC@CCCBB,8??:555?@
@7PQ
GTGTGAAATGCCTTGCTATACATCCTGACAAAATTAGGATTGCAACTGGACAGATAGCTGGCGTGGATAAAGATGGAAGGGTGAGTGGCATAGTGTTATGC
+
==<+<>@@B7+2+47C7=@B7A4,<3?>+2+2+?311:?ABB47??00?0=AA**9?<==9AA:A4(733)).7>@).;<=>;==-;;(,:9>(,(,:>99
@7PR
AGAAGACCCTAACAGTCCAGCAGGAAGAAGGCATTTGCAGCTCCAGACTCAATTAGAACAGCTCCAAGAAGAAACATTCAGACTAGAAGCAGCCAAAGATG
+
@CCFDDEFHHHHFGIEGGIGGHIIJIIIJEGGDHIJJIFIIEGHIIIGJIIJJJIIJIJIIIIJIJGIIFHGHGFDFFFECCEEEDDDCCCDDDDCDDDCD
@7PS
AGAAGCCACAAGTGGGAATGAGGCCCTCCAACCCCCCCACACCATCCAGCACGCCAGTGTCCCCACTGCATCATGCATCTCCAAACTCAACTCATACACCG
+
CCCFFFFFHHHHHIJJJJJJJJJJJJJJJJJIJJJJJJJJJJJHHHHHFFFF>CDDDDDDDDDDDDDDDDDDDDDDDEDDDDDDDDDDDDDDDDDDDDDDD
@7PT
TTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGC
+
CCCFFFFFHHHHGJJIJJJIJJJJJIIJJJIJJJJJJJJJJJIIJJJJIJJJIIIJIGGIJJIHHH?EEFFFFFE>CEDDDDDCDCDDDDDDDDDDDDDDD
@7PU
ACCAAGTCATACCAGTGCTGTCTCAATTGCAGGAAAAGAAACTCTTTCATCTGCTGCTAAAAGTGGTACAGAAAAAAAAGAAAGAAAAACCACAAGGAC
+
B@@FFFDFHHHHHJJIIJJJHJJJIJJIJIIIIIIJJJJIJJJJJJJJJJJJJIIJJJJIJII=EH8CHIJGJJJJHFDDDDDCDDDDDDDDBDBBDDD
@7PV
CAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCAC
+
CCCFFDFFFHHGFIGIIHIIIIJIGJJIJEFFHIHIIIJHHIJJIGIAHEHIIJJJIFJDGHHHGHHHDFFFFFDEACDDDDDDDDDDDDDDDDDDDDDDB
@7PW
GCGTGATCCAGCTGATGCCCAGCCCCATCATGCACCCTCTGATCCTGAACCCCCGGCACTCCGTGGATTTCAAACAGTCCAGGCTCTCCGAGGACGGGCTG
+
B@CDFDFFHHHHHJJJJIJJJJJJJJJJJJJIJJIJJJJJIJJJJJJJJJJJJJJJHHFFFEDCDDDDDDDEDDDDDCDDDDDD@DCDDDBDD>BBDDDDD
@7PX
GGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTAC
+
CCCFFDFFHHHHHJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJIJJHHHHHFFFFDDABDDDDDDDDDCCDDDDDDDEEDDDDDBDDDDDDD
@7PY
CTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTT
+
=?@DDDDEHFF?BFGGGEEGIIIGI<CHI@GGIEGIIIGIIBGGGIGIFFHIIIFEHEBGHFFH?E>BDFFFFCCBBBCC?B?BBBBB@C@ACDC@B+50?
@7PZ
ATTTTTATGTTAAATGGTTATATTTTAAGTGTTTGTGAGCTTCATTTCTATCATGAATAAATGTATTCCTTTTTCATCCACAGGCTGTATGTTTGAAAAGG
+
CCCFFFFFHHHHHJIJIGIJIJJJJJJJIJJIIJJIIJJJJJJJJJJJJIJIIIJJJJJJIIJDFIIJIJJIJIIJJJJJJJJJJHHHHHEEEFFFFEEED
@7Q0
CGGGAAGGACCCACATACCAACGGCGAGGATCACTTCAGCTCTGGCAGTTTTTGGTAGCTCTTCTGGATGACCCTTCAAATTCTCATTTTATTGCCTGGAC
+
@CCFFFFFGHHHGJJJJJJJGIJIJIIJJJIJIJJJJGIJJJJHHHFF>CFFFCDACDDCDDDCCDDDDCDCDDDDDDDDDDCDDCDEEEDDDDDDDDDDD
@7Q1
CCAAGCCCTCGAGCAGTTATTCCCATGTCCTGTATAACCAATGGAAGTGGTGCAAACAGAAAACCAAGTCATCCCAGTGCTGTCTCAATTGCAGGAAA
+
CCCFFFFFGHHGHJJJHIIJJIJJJJJIJJJJHIJJJJIIIIIJIIJDFHFHIIIIJJIJJJJJIJHHGHHH)?BFFCEEEDCDDDEDDEDDDDDBDD
@7Q2
CCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTC
+
CCCFFFFFHHHHHIJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIHHHHHFFFDDDEEDDDFDEDDDDDEDDDDDDDDD
@7Q3
AGAGAGATATGTCTACAAGTTTGTGTGTGATCCAGAAGCCCTTTTCTCCATGGCCTTTCCAGATAATCAGCGTCCACTGCTGAAGACAGACATGGAACGTC
+
CCCFFFFFHHHHHJJJJJIJJJJFHIHGIIJIJJIJJIJJIJJJIJIJJJJGJJJJJJJIIGIIIJIGIGHIEHBHHFFFFFFEDEEEDDDBDCDCDDDDD
@7Q4
AGATAGTGCAAATGAAACAAGAATTAATAAGACAACACATGGCACAGATGGAGGAAATGAAAACACGGCATAAGGGAGAAATGGAGAATGCTTTAAGGTC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJHIIJIIJJJIIJJJJJIJJJJHHFFFFEEBDBDDDDDDDDDDDDDEDDDDDCD
@7Q5
ATTGAAAAACTTAAAGATAATTTAGGCATTCACTATAAACAGCAGATAGATGGTTTACAGAATGAAATGAGTCAAAAGATAGAAACCATGCAGTTTGAAA
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJGIIJIHGIJJJJJJIIIJIJJJJJJHHHHHHFFFFFEDEEEEEDDDD
@7Q6
GAACGCCTCCCCGAGTGAGCTGCGAGACCTGCTGTCAGAGTTCAACGTCCTGAAGCAGGTCAACCACCCACATGTCATCAAATTGTATGGGGCCTGCAGCC
+
@@@DFDFFDFHFFI@EBF9ECGHA@F:FG?BFGCF@FH>CBCE>FHEFGDEEFGFECDE;@@>A@BCBCBBBCCDACDCC@ACC>>A>@CAB9<<??<CCB
@7Q7
CTCACATTGCTGTTGCTGCTATTATTTTTCTTCGTCTTTTTAGGAGGAGGTTCCTTGGCTTTGCTTTTTTTATT
+
@@@DFFFFHDFDHIH@FHEHIIGGIIIGCFFHEGEBDGHEGGIJEHHDHHFHHIIIJIEIIIJJJIJGIHFDEE
@7Q8
GTCAAGAACAGCCCTTTAAATTCAGCTATGGAGAAAAGTGCCTGTACAATGTCAGTGCCTATGATCAGAAGCCACAAGTGGGAATGAGGCCCTCCAACCCC
+
81?DD;?ABFBFFBFGBG<FBFEHBHBH<A?C;GHBHB1:C?B?:D@G?0B9??8*9?B?C<88).=FH@F9==@EA=.7=6?7(;A6.,(,,,(5?(838
@7Q9
ATGAGGGTTACCTATGGGACTGAAGGACTGCAGCAGTTACAAGAATTTGAAGCTGCCATTAAACAAAGAGATGGCATTATAACCCAGCTCACTGCTAATTT
+
CCCFFFFBFHHHFIJIJJJJJJJJJJIGEHIJIJIIGGIJGGGDEGHJJJJJJIJJJGIJIIIJJJJJIJHHHHHFFFFFFEDECDDDDDDCCDDDDDDED
@7QA
CACACAGGTCAGCAGACAGGGCCAAAGGAAAGGAGAAAAAGAAAAAGGAAGCAGAGGAAGAGGATGAGGAACTCTCCAACTTTGCTTACCTCTTGGCCTCT
+
@@@DDFFFFHHHFEGHGIBHI?DGIJJIJGJJIHHGIJIGEIJJIIGICGHHIJIGJHFEHHFEFFEECCCBCDDDCCDDDCDDACCCCACDDDDCCCDBD
@7QB
TCCAAACTCAACTCATACACCGAAACCTGACCGGGCCTTCCCAGCTCACCTCCCTCCATCGCAGTCCATACCAGATAGCAGCTACCCCATGGACCAC
+
C@@DFFDFHHHDFEHIJJIGFHIGIJGEHGIIIIIIHJIIJJJGG@HGIJEEEHEFFFFEDDCD=?CCEDDCCCD@ACCDCBCDDDDDD?C?CDDAD
@7QC
CTTCAAATCAATGAACTTCAAAAAGAAATTGAAATACTCAGACAAGAAGAAAAAGAAAAGGGTACACTTGAACAAGAAGTTCAAGAATTACAACTTAAAAC
+
CCCFFFFFHHHHHJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJFFHJJJJJHHFHHFFFFDEEEEEEEDDDDDDDDDDDDDD
@7QD
CGCCTAGAGGGAAAGCGAGAGGGAGACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGC
+
CCCFFFFFHHHHHJJJJJJIJJJHIIIIJHIJGIJIJJJJJJJIHHFFF?CEDDDDDDDDDDDDDDDDDDDDDDDDDDDDDEDDDDDDDDDDDDDDDDDDD
@7QE
CCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGT
+
CCCFFFFFHHHHHJJJJJJJGIJJJJJJJIJJIJJJJJJJJJJJJIJJJJIJHHHHHHFFFFFFEEEEEDDDD@CDDDDDDBDDDDDDDDDDDDDDDDDDC
@7QF
GGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATC
+
@@@FDDE?DHHFHGGBGHGIJJIJJJIIJJIJJJIJGJJIHJJJJJJJGIJIIJJJJJJJJJIIJJHFHEHHFFFFFFEEECEDBDDDDDDDDDBBDDDDD
@7QG
CTGTCAGTATTTGGAGGAAAACCACTTCATCCACCGAGACATTGCTGCCAGAAACTGCCTCTTGACCTGTCCAGGCCCTGGAAGAGTGGCCAAGATTGG
+
CCCFFFFDHHHHHJIJJJJJJJIJJJJJJJJJIJJJJJIJJJJJJIJJJIIIIJJIIIIIJIJJIIHEH?EFEFFFDDDEDBDDBB3>???CBBDCDDD
@7QH
CAGTAAGGTACGGAGTAACTGTCCAAAAGCCATGAAGAGATTAATGGCAGAGTGCCTCAAAAAGAAAAGAGATGAGAGACCACTCTTTCCCCAAATTCTCG
+
@??DBDFFHDHHHJIHHGIIGHHIIIIIIJJEGG@GGDHEHGGEGEHGHGIG8C=CAHIEGGIE=DCEEAE@DDFBDEACC=A?CCDC@CDCCD?CDDDD<
@7QI
TTTAATTATGAGGAGAGAACTCAGCGACACTACCTGGGCCATACAGACTGTGTGAAATGCCTTGCTATACATCCTGACAAAATTAGGATTGCAACTGGAC
+
@@@FFFFFHHHDFGHJIBGGFHIIIGIIJJGIGIGGDFEGGEIIJDEEGICF@FGIIGIBGGHFHHGFFDFCDECCEEEDDBDDCCCCCDDCCDDCCD??
@7QJ
TTTCTATCCCCAACCACCCCTCAACCCCTGTTTTCCCCTGCCTTCCTTGCAGAGGCCATGGAGGACGAGGAGAGACAGAAGAAGCTGGAGGCCGGCAAAGC
+
@@@DBADDHF?FHDEHDGDEEFHGDHFGG;?D>GIIADDGDFGICEC8=CH=;FD;@GIEE)=??=3=;>BBB@BCCC::A>?9>:@C<A<??BBBBBB?C
@7QK
CTACTTTTCATAGAATTCAGGACCAACTTCAGTTATTCAGAAATTTTTTCTTAAATAGCATTTATAAGTCCAGAGATGAAGCAAACAACAGTGGAGTCAT
+
CCCFFFFFHHHHHJIJIJJIJJJJJIJJIIIJJJJJJJIJJIIJJJJJJJJJJJJJJJJJJJJJJJIJGHJJJJJIIHHHHHFFFFFDDDC>ADDDACDE
@7QL
CTCTGTGTGGGAAAAAGAAATAGAAATACTTATAGAGGAAAATGAGGACCTCAAACAACAATGTATTCAGCTAAATGAAGAGATTGAAAAGCAAAG
+
C@CFDFFDDDH?HIGGHGBBCHFHH@CGGAHGGHCCHCFGIIBFH?BBDGGEHII@DBFAHGEAEHIIIIHHHFH@ABFECD@A;>CCDDDDDCCC
@7QM
AGAAAAGGAGATCTCTGAACTTCGGCAACAGAATGATGAACTGACCACTTTGGCAGATGAAGCTCAGTCTCTGAAAGATGAGATCGACGTGCTGAGACATT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJIJJJJJJIHHHHHHFFFFFFDEEEEEDDDDDBDDDDDDDDDDD
@7QN
AGGAGAGGGTCTGGGAAGGTTATAAACCAGGTATCTCTACATCAGGATGGCCATCTAGGAGGCGCTGGGCCTCCTGGGCACTGCCTGGTGGCTGATAGGAC
+
@@@DDDDFH?DHHIIIIIJFEHGIIIHHIJJ<FIIJJIIIIIIJHGG@HIIFHIJJGIJ@HGDHBBCDD?BDDDCDDD?CDDDDDCDD(<B?A@ACCDDCC
@7QO
CAGCTTCTATTTAGTCACGAAGAAGAGCTTTCCAAACTGAAGGAAGATTTAGAAATTGAACATCGAATAAATATTGAAAAACTTAAAGATAATTTAGGCAT
+
@@@FFFFFHHHHHJIJJJJIJJJJJJJJJJJJJJJIJJJIJJIJJJHIJJJIIJJJJJIJIJIJJJJIIIJIHGHFGHHFFFFEEEECEEDDDEEDDCDDD
@7QP
GCCCCATCATGCACCCTCTGATCCTGAACCCCCGGCACTCCGTGGATTTCAAACAGTCCAGGCTCTCCGAGGACGGGCTGCATAGGGAAGGGAAGCCCATC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJGJIJJJJJJJJJJJJJHHIHJJJJJHHHGHFFFFFFDEEEDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDD
@7QQ
CTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCA
+
=?@=DBD?;FF;<FGBG<AEGHBAF<DABF3?DF@(/??<*=;@5@FGBG@EHEH7;3;CDECCDDCC>>?B=AC@:@ACC>CC3,:
@7QR
CATGATCCGCCGCCTCTCCCCGGCTGAGAGAGCTCAGGGACCCAGGCCGCACCAGGAGAACAACCACCAGGAGTCCTACCCTCTGTCAGTGTCTCCCATGG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHHFFDDDDDDDDDDDDDDDDDDDDDDDD?CDDDDDDDDDDDDDDDDDECDDDDDDD
@7QS
CAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGC
+
CCCFFFFFHHHHHJIIJJJEGIIIJJJJJJFHIJJJJJJIJJJJJJJJJIJJJJJJIJIJJJJJJHHHFFFFDEEDEDDDDEDDCDDDCDDDDDDCDEDD
@7QT
CTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCT
+
?88A:2:AA:AB@EAGIB;29:?*C@G?@FC?F0??BBBD?*09BFACBDFFI;;8@@DEEIFFCDD>;;@==>?;A;5>;A3?B7@@<?B@B@>?B:A?:
@7QU
GCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATC
+
@C@DDDFFHGHFHGIIJJFIIIJGGIJIJEDCFGEFGIIIJGGI>BGAFGHCA8AEEHFEFF?=ACDBDDDDC?CCDCADD@CDBDC:@CCDC@CCCCCDD
@7QV
GACAAGCACAAAAGGAAAGAGGGAGTGGAAGAGAATAAAAAAAGCAAAGCCAAGGAACCTCCTCCTAAAAAGACGAAGAAAAATAATAGCAGCAACAGCA
+
00(-@312);.28.=?5:<?9>(<9(6().=?5)09>>?8.<=4>;?;;)<>;;9>;(5;(99(.(997<7;;(,,888586282/(+8(5//+8529<<
@7QW
AACTCTTTCATCTGCTGCTAAAAGTGGTACAGAAAAAAAGAAAGAAAAACCACAAGGACAGAGAGAAAAAAAAAGAGGAATCTCATTCTAATGATCAAAGT
+
@CCFFDFFGDHBHIGEHIJJIJJGAFGFHIGIFGHIJIIHGDHDDHDGGGIIJJIIJEGHHEE?B?@@CA@B@BD<CBABDDDCCEEEEDDEDCCCDDDD:
@7QX
GCCTTCCTACCATGCCCACCAGCAGAAGGTGAACTTTGTCCCTCCCCATCCATCCTCCATGCCTGTCACTTCCTCCAGCTTCTTTGGAGCCGCATCACAAT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJGGIJJJJJJGIIJJJJJJIJJJJJJJIJJJJJJJJJJJJJHHHHHHFFFFFEDEEEEDCDDDBDDDDDDDDD
@7QY
ACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJHIJJJJJJJJJJJJJJJJJJJJHFFFFDEEEEDDDDDDDDDDDDDDDDD<BDDDDCDDDD@CD
@7QZ
TTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGC
+
??1:AADDDDDDBAC:C?A<AB?FE:C;EFDFEBDE9CAB>DDC?D<D:ACB8AEI>@3A;;AACCDCDA>DDA@..;A3>>=;;;<9>55>A???><828
@7R0
GCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTAT
+
CCCFFFFFHHHHHJJJJJJHIJJJJJJJJJJJJJJJJJJHHJJJJJJIJJJJJJJJJJJJJJJJJJJJHHHHHHFFFFFEEEEEDDDDDDDDDDDDDDDDD
@7R1
GATTACTATAGAAAGAGAGGGGAAGGCCTGCTCCCAGTTCGGTGGATGGCTCCAGAAAGTTTGATGGATGGAATCTTCACTACTCAATCTGATGTATGGTC
+
C@CFFFFFGHHHGJIBHIIGIGHGIJJJIIJIJJJIIGIHHI?FHGIIIJIGJIJGGGHEHFH@CFF@DEDDEDCCDCDCDCDCCCDDCCD:AC@CDDDCC
@7R2
CTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJIJIJJJJJJJJJJHIIJJJIGIHIIJJJJIJJJJIGIJJJJHGFFHFFFFEEEEEDDDDBDBDCDDDDDDDDDDB
@7R3
CAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCT
+
CC@FFFFFHHGHHJIJJJJJIIJJIJIIJJJJIIJJJJJJJJJJJJJJJJJJJJJJJIJHHHFFFFFFCEEDDDDDDCDDDDEDDDDDDDDDDDDDDDDD
@7R4
CGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGG
+
@@CDDFDFHHHHDHIJGJJJJJJHEHGDGHGIIGHIGAHDCGFFGGIJIGJIIIGCHGGFFFEDDDDDCDCCCBDCCDDDDDDDD?CDDDDDDDDDDDECD
@7R5
CCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGC
+
CCCFFFFFHHHHHJJJJJJJJJIIJJJJJJJJJJJJJJJJJJJJJJIJJJJHIJJJJGJJJIJJJJJHHHGHFFFFFEDDEDCDDDDDDDDDDDDDDD
@7R6
CTGTATGGGACTGGCAAAAGAAAGCAAAAGGAGCAGAAATAAAGACAACAAATGAAGTTGTTTTGGCTGTGGAGTTTCACCCAACAGATGCAAATACCAT
+
?<@=ADD?FAC??3AA+AC?F@<A?CFCDE:FBD??BBGIGHGIDGGH;;=88BF@C78==@AHDA>E=.;>@?AA>@6>CBBBB8?A@ACCCCCCCC>@
@7R7
CGGCGCTTTCCCCGCAAGATGGAAGGTTTCGCCGGCAGTCTCGATGATAGTATTTCTGCTGCAAGTACTTCTGATGTTCAAGATCGCCTGTCAGCTCTTG
+
@@<DFDDFGFFGHJJIGIFIJFHIJI9DGHHIIIJGIBEHFFFDDEEEDE>BFEEECCDCDDDDCACCADCCCEEA>CDDECDCCB?@>A@ACCCC:ADC
@7R8
CTCCGGTCCCCCCTGGACAACATGATCCGCCGCCTCTCCCCGGCTGAGAGAGCTCAGGGACCCAGGCCGCACCAGGAGAACAACCACCAGGAGTCCTACCC
+
CCCFFFDFGHHHHJGGIIHJGGIJJIJJIGIJJGIJHIIIHHEFCDBBCDBBDDDDDDBBDDDDDDBBDDBDD?DDDDDBCDDDDBDD@BB<@ACDCDDDD
@7R9
GCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTC
+
@@@FDDDEDHBFFGHIIGIIGHIGAHIIBHIJJJIGHBGGIGCGIIGGGHIIG@EHFHHHF4>CE@?>CCC?5=CDDDDDDEDDDC@??ACCCDCCCC4:
@7RA
GGAACACTTTTTCATTTGCTGAAAAAAACTTTGAAGTTAACTATCAAGAGTTACAAGAGGAGTATGCTTGCCTTCTCAAAGTAAAAGATGATTTAGAAGAC
+
CCCFFFFFHHHHDIJIJIIJJJJJJJJJJJJJJJIJHJIIIJJIJJJJIHGIJIJJJIHJHICHIHGHHHHHFFFFFFEEE@CEEDDBACDECDDDDDDDD
@7RB
CAAGCCTTCAAAAATGAAGTAGGAGTACTCAGGAAAACACGACATGTGAATATCCTACTCTTCATGGGCTATTCCACAAAGCCACAACTGGCTATTGTTAC
+
CCCFFFFFHHHHHJJJJJJHJJJJJGIJJIJJJJJIJJIJJJJJJJIJJJJIJJJJJJJJJJJJJJIJJHHHHHHFFFFFEEEEDDDDDDDDDDDDDEDDD
@7RC
CCACATACCAACGGCGAGGATCACTTCAGCTCTGGCAGTTTTTGGTAGCTCTTCTGGATGACCCTTCAAATTCTCATTTTATTGCCTGGACTGGTCGAGGC
+
CCCFFFFFHHHHHJJJJJJJJIJJJJJGIJJJJJJJJJHIJJJIJHHHHHHFFFFFFEEEEEEDDDDDDDDDDEDDEEFEEDDDDDDDDDDDDDDDDDDDB
@7RD
CAGAGTCAAAAATTACAGATTCAATTTCAGCAATTACAGGCTAGTGAAACTCTGAGAAACAGCACTCATAGTAGCACAGCTGCAGACTTACTACAAGCCA
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJGHIJJIIJJJJJJJJJJIJJJJJJJJIDHHIJGIGHHHHFFFFFEEEEEEDDDBDD
@7RE
CGTATCAGATCCTGGGCCCGACCAGCAGTCGCCTAGCCAACCCTGGAAGCGGGCAGATCCAGCTGTGGCAATTCCTCCTGGAGCTGCTCTCCGACAGCGCC
+
@@?DDFFFGFFFHA?E;FGIIIIIIIIGHHE>HIIGIIIIGGGGGIBHGGGFDB>BB:>CCCCCCCCCCCCCCCA@CCCCC<ACBCCCC3@CBB>@BB@BB
@7RF
CGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCA
+
@@@DFDDDHHHHHGIEIJJGHIIHIJIIJJJJJIJJJJJFHJJIJIJHIJJIJIIHHFHGFDDDDDDDDDDDDDDCCCEDDDDDDDDDBDDDDDBDDDD
@7RG
CAACAAACAGGGGGTCGTGGAGTGCTTCCTCAAGGGAAGGAGCCTTTAGCAGTGCCCTGGGAAGGCTCTTCAGGAGCCATGTGGGGAGATGACAGAGGTAC
+
CCCFFFFFHHHHHJDHHGHGJJFHHJJJJJJJJJJJIIJJIEHIHGDHHCDFCEFFEDEDDDCDDDCDCCCCDDDDDDDDDCCDDBBDBDDDDACCCD>AC
@7RH
GTAACTTCTGCTTCATGTTTTAATTCTAGTTCCTTTCTGGATTCAGATGCAGAAACAATCTCAGCTTTCAAATCTTCCACTGTACTAAGGGACTTATGTGC
+
?@@DDDDDHHHHHJJJJEIJIGFIIGIJJHIIJJIIJIIIIJIJJJIIIJJJJJJJJIIJJJJJJJJJIGGIJIIJHIGIIIIJIHHHHHFFEDFEEEDEC
@7RI
GGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATC
+
@@@DFDADFFFHFEFGHIJAHIGIGIJAHIIDIGHGGIGHGJJIIJ@BCGCHHIJIIJ7CEHHHGFFBA@CEEBDDCDDC@CDBBACCACCDCCDDDB9CC
@7RJ
CCAAATACACAGACAAACTCCAGAAAGCAAGAATGCTACTCCCACCAAAAGCATAAAACGACCATCACCAGCTGAAAAGTCACATAATTCTTGGGAAAATT
+
@@@FBD?DHHHGFGGHIGCGCHIIIII>GGFGIGDHEIGFEIGGIIIIFHHIGGHIIIIEGGHHHEDFF@BBCE@ACCC;AACCCCCCEDEDCCBBCCCCC
@7RK
CGGCCCCAGCCAGAACAGTATCAGATCCTGGGCCCGACCGGCAGTCGCCTAGCCAACCCTGGAAGCGAGCAGATACAGCTGCGGCAATTCCTCCTGGAGCT
+
-7(8-@;<52(:.()2)2@<??>).))2))1((:=9(</'5=?4).''(3/(6;;;3;;<7<807:-(&))((+(5:8;(2(0&&)0+(5(+675((+26(
@7RL
CCAGAAGTCATCAGAATGCAAGATAAAAATCCATACAGCTTTCAGTCAGATGTATATGCATTTGGAATTGTTCTGTATGAATTGATGACTGGACAGTTACC
+
@<@DDDFDBFHD>DFH@GHE:CEFHHI>CC<EA@FIGHC9G9C9D??GC@<F99?FBAC?B@GAFCGC=>=CA@C7=CGIIEHICHEHEFF=?>C?;>CCA
@7RM
CCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTTATGGGCAGGAGT
+
?<?DBD;==22ACEE4C@B?3AB:+:CF@@CBD@ECCDD9@DD<DDIDD;CCC=4@A;;ADDAD?;?>?;=9;==5>><(55<?A>5<9A>>>><?9;?>3
@7RN
GTACCACGACCCAGTGTATGAACACAACACCATGGTTGGCAGTGCGGCCAGCCAAAGCTTTCCCCCTCCTCTGATGATTAAACAGGAACCCAGAGATTTTG
+
BBBFFFFFHHHHHJHIHIJJJJJJJJJJJJJJJJJGIJJJJJFHIJJJJHHHHFFFFFEEEEEEDDDDDDDDDDEDEEFEDDDDDDDDDDDDDDDCDDDDD
@7RO
CCCATTACCGGTATGGGGTGAGCCCCCCGGGGTGTGGGGCAGAAAGGAGGAAGAACCCCACATGGAGCAGGCGGCGCCAAGTGGGTGTGGAAACCATCTCT
+
5(0=34)).:5-88.:?((1@11615(-('5/--'((',33'((3(((,3(222++()&(&+(28:(6985&)50500&)8568(&))(2:<(6(+(53:(
@7RP
GGATCAACCACAGGTTTGTCTGCTACCCCCCCTGCCTCATTACCTGGCTCACTAACTAACGTGAAAGCCTTACAGAAATCTCCAGGACCTCAGCGAGAA
+
@CCFFFFFHHHHHJGGIIJJIJIJJJJJJJIJGIIGIJJIIJIJIJIIIJHHHFHHFFFFFEDCDDDCDDDDDDDDDDCCDCCDDDDDBCDDDCBDDBD
@7RQ
GTCTACAAGTTTGTGTGTGATCCAGAAGCCCTTTTCTCCATGGCCTTTCCAGATAATCAGCGTCCACTGCTGAAGACAGACATGGAACGTCACATCAACG
+
CCCFFFFFHHHHHJJGIHIJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJIJJJJIJIIJIIJIJIJIJHHHHHFFFFFEEEEDDDDDD?BCDDDDDD
@7RR
CTATCAGACTAGCAGCGGACAGTACATTGCCATTGCCCCAAATGGAGCCTTACAGTTGGCAAGTCCAGGCACAGATGGAGTACAGGGACTTCAGACATTA
+
C@CFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIHIIIGJJJJJJJJIJIIIHHHHGFFFFFEEEDECDDDCCDCEDDDDDDDDDDDDDDD
@7RS
GAACCACATCATGGTCTCTGTCTCCCCGCCTGAAGAGCACGCCATGCCCATTGGGAGAATAGCAGACTGTAGACTGCTTTGGGATTACGTCTATCAGTTGC
+
CCCFFFFFGHHHHJIIJGJIIIJJJJJJJJGIGIGGIJJIJIJJGIHJJIIIGJJDIEHHFHGFFFFFE@DEDACDDDDDDDB?CDDDBABDBEDDECDDC
@7RT
GGACGTCCTATGTACCAACGCCAGATGTCTGAGCCAAACATCCCCTTCCCACCACAAGGCTTTAAGCAGGAGTACCACGACCCAGTGTATGAACACAACAC
+
?@@DDDDBHDFHDFEFHIIIBFBGIJIIJAHIEEHHHIIIJGHIGGBHJIIJJJIGGIIFFHHFDDEEDD?A>>CACCBD@BB<A@CCCCDC>@CCDB?BD
@7RU
GAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTC
+
CCCFFFFFHHHFHJJJJJJJJJJIJJIIHIJJJJJJJJJJJJIHJJJJGIEHHHHGHFFFFFEDDDDDDDDDDDDDDDCDDEDDDDDDDDDDDDDDDDDDD
@7RV
CTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTAT
+
CC@FFFFFHGHFHFIBEADHIIGHFHIJHGIGGIGEGIIGGGGG>@ECHGEH?AEHCECBE3@C@EC=AAC;>@CCC@CDDC@CB@BBDDDDBBDCA@CCD
@7RW
TTTCTTTTGAAAATATGACTGTTGGAGAAGAAAGTAAGCAAGAACAGTTGATTTTGGATCACTTACCATCTGTAACAAAGGAATCATCACTTAGAGCAACT
+
@@CFFFFFHHGHGJJJIEIJJIIJJIJEIIJJJJIJIJIJIIJJJJJGHIHJJJJJJIIJJJJJJJJJJIII@GHGHGGGHFFFDFEEEEEEDDCDDDDDD
@7RX
CCTTATCATGGGGACTGAGGATGCCTCCTCCTTGCCTGAAGCCAGTCAAGAGGCAGGGAGCAGAGGCAATTCCTTTTCTCCTCTGTTGGAAACCATAGAAC
+
CCCFDFFFHHGHHJJJJGIJIIJJJJJJIJJJIIIJJJJJIJJGIIJGJDIIIGGIJIHHFHGHFFFFCCEEEDDDDDCDDCDDDCCCDCDCDDDDDCDDD
@7RY
ACCAGATAGCAGCTACCCCATGGACCACAGATTTCGCCGCCAGCTTTCTGAACCCTGTAACTCCTTTCCTCCTTTGCCGACGATGCCAAGGGAAGGACGTC
+
CCCFFFFFHHHHHIJJJJJJJIJJJJJJJJIIJJJJJJJIJIIJGHJJIJJJIJJHHHHHHFFFFFFEEEEEEDDCDDDDDDBD?BCCDDDDDDDDDDDDD
@7RZ
GCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGC
+
CCCFFFFFHHHHHJJJJJJJIIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHFFFFEEEDEDDDDDDDDDDDDDDDDEDDDDDDDDDDDDD
@7S0
AATTTGACTTCCACGGCATTGCCCAGGCTCTGCAGCCACATCCGACCGAGTCGTCCATGTACAAGTACCCTTCTGACATCTCCTACATGCCTTCCTACCAT
+
CCCFFFFFHHHHHJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHFFFFDEEEEEFDDDDDDDDDDDDEDDDDDDDDDDDDDDDDDDDDDDDDD
@7S1
AAATAGGTGATTTTGGTCTAGCTACAGAGAAATCTCGATGGAGTGGGTCCCATCAGTTTGAACAGTTGTCTGGATCCATTTTGTGGATGGCACCAGAAGTC
+
CCCFFFFDFHGHHIJJGIJJIJJJJJJIJJJJJJJJJIJJJGIBFHIGJJJJJJJJJJIJJJJJJGIIHIJJHHHHHHFFFFFDEDCECBCCDDDDDDDCD
@7S2
CTGGCTAATGCCTGCTATGCAATACATACTCTTCCAACCCAAGAGGAGATTGAAAATCTTCTTGCCTTCCCTCGGGAAAAACTGACTCTGCGTCTCTTGCT
+
CCCFFFFFHHFHHIJJJIJIJIJIIJJIIIIIJJJJJJJJJIJHIJIIAHHIHJJIHGIJIIJJJJJJJJJJJHHFFDDEEDDDDDDCCCCBDBBCDDDDC
@7S3
AGAAGATTATCAGAAAAAAGAAAGAAGACTTCACAATGCAAATTAGTTTCTTGCAAGAGAAAATTAAAGTATATGAAATGGAACAAGATAAAAAAGTAGA
+
@<@DADEDHHFHHEHIGIIDEHIIIGIIIIIGIGHIG9DHDFDDDD9BGBGHHGEGGCC@CG@HGDEGAD?C;?ACAACD@BE<ACC>ACDDDDB@CDDD
@7S4
CTTCCTCGACGCCACTTCATGTTCCAGTGCCTCGAGCGCTCAGGATGGAGGAAGACTCGATCCGCCTGCCTGCGCACCTGCGCTTGCAGCCAATTTACTGG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJHIJJJIIHIJJJJJJJJJJJJJJHHHHEFFFFDEEDDDDDDDDDDDDBBDDDCDDDDDDDDDDDDDDDDDEDDD
@7S5
AAGTAAGCAAGAACAGTTGATTTTGGATCACTTACCATCTGTAACAAAGGAATCATCACTTAGAGCAACTCAACCAAGTGAAAATGATAAACTTCAGAA
+
@CCFFFFFHHHHHJIJJJJIJJJJJJJJJJJJJJJJJJJJJGIJJJJJJJJJJJJJJJJJJJJJIIJJJIJJJJIHHHHFFFFFFEEEEEEEDDDDDDD
@7S6
CCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCT
+
@CCFFFFFHGHHHJJJJJJJJJJJJJJJJDFHIIIJJJJJHHIJJJJIIJJJIJJJJJJIJJIJJHHHHHHFFFFDDDDDDDDDDDDDDDDECDCDDDDDD
@7S7
AGGAATCGAATGAAAACACTTGGTAGACGGGACTCGAGTGATGATTGGGAGATTCCTGATGGGCAGATTACAGTGGGACAAAGAATTGGATCTGGATCATT
+
@@CDFFFFHHHHHIJJJJJHIJJFFHIIHGJGHIGGGH9BDGIGGIJIJJJGHEHGFHHGIIJHFHEBDFFFFCCCDAABDCCDBCDCCCCCCCDDDDDDD
@7S8
CAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCAC
+
CCCFFFFFDDFHHIDGGGGIIIHIIIIEGIIHGIIIGGGIIFGGAHGGGGGGEGHIIGFHFDEEC@DEEACBBBBBDCCCCDDCC??<A>CCCCC@A@?B@
@7S9
AGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATAT
+
CCCFFFFFGHHHGIJJJJJJJJIJIIJJIJIJJIJJIJJJGHIIEHIJJJJIJJJJJIHHHHGFFFFFFEDDDDD=BDDDDDDDDDDDDDDDDDDDDDDD
@7SA
GCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTC
+
CCCFFFFFHHHHHJJJJJIJJJJJJJJJJJIJJJIJIJJJIJJIJIIIGIJIJJJIJJJGHHFFHFFFFFFDEEEEEDBDDDDDDDDBDDCCCDEDEDDDD
@7SB
GGCATTCAGAAAAACAGGCCAGATATGAACTATGATAAACTTAGCCGTTCACTCCGCTATTACTATGAGAAAGGAATTATGCAAAAGGTGGCTGGAGAG
+
??<=D?AACDDDDIDIDD:ACF8CEE?FE9*?EEECFIEIEFIIICDD?DDE9BBDAAADAECEIECACCDADD;A>?A>>(;>A?A=-;<??=:9?A<
@7SC
TGAAAGATGAGATCGACGTGCTGAGACATTCTTCTGATAAAGAATCTAAACTAGAAGGTCAAGTAGAATCTTATAAAAAGAAGCTAGAAGACCTTGGTGAT
+
=<;;AA3A<,<A<AAA7<32?C<*?=ABB?ABBB=ABBBB?<*0=7??<?3==ABB92.)==A.=)77==>AAAAAA>>6=>>>>(6=;;>9=;>>?==35
@7SD
GTTGTCTGGATCCATTTTGTGGATGGCACCAGAAGTCATCAGAATGCAAGATAAAAATCCATACAGCTTTAAGTCAGTTGTATATGCATTTGGAATTGTTC
+
==<?7<,<?A>=A9C<A<<3<+?+33@C@?3=@@3:?=4*:=**0*?A709>BBBBABA=)><A=.)...)...=A9)7=.)7).7;;7;;5>;>;>?;=?
@7SE
AGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGG
+
1=@??DDDDHHHHGGBHG@E@@EG@EFH4?CFGIF@GIIGH?FEGGBHIECDEBCGGCDFHIIG>6CE?EHEECB@CB;@C@@@C:@(5<<?4>CC4@>:>
@7SF
AGAGAAGTGCATGGTGGGCAGGAGCAAGCCCTAGATAGCCCCAGAGGGATGCACAGGGATGGGAACACTCTGCCATCCCCCAGCAGCTGGGACCTGCAGCC
+
@<?DDDD22A?F>F<AF>DF@A@FCFFGII?B9?<:DFDCBADFFCFFF@F>E=@DEFACDDD<>@2;>AB@BB@ABBB<@BBB?2<3><?B@<3<BBAA2
@7SG
ACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJIJJJIJJJJJJJJIJJHHHHHFFFDDDDDDD?BCDDEEFEEDDDDDDDDD
@7SH
CTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCCCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACT
+
?@7::A=?2ACFDFFF<C@F+3AFFE<F=E@@AEIF>F*C:B9;BF<?FA(?;A;F;;7@7==DEEF:;?:7;5;?BCCCBB;;=@A@(5>,,:AB>AB(>
@7SI
ACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCG
+
@@@FDFFFDHHHHGIJIBIIIIJJJIJJJJIGIIGIIJIJJJJJJJJJGIIJIGHDGCEGGIJJIHHHHFFFFEDDFEDEEEDDCDDDDDCCDDCDBDD
@7SJ
CAATACCACAGGAAGAGGCGTCCTTAGCAGAGACTGCCCTAACATCTGGATCATCCCCTTCCGCACCCGCCTCGGACTCTATTGGGCCCCAAATTCTCACC
+
CCCFFFFFHHHHHJJJJIJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJHHHHFFFDDDDDDDDDDDDDDDDDEDDDDDDDDDDDDDEDEDD
@7SK
CAGCAATGTGAGCAAGAAGGAGCCAGCGCCCATGAAGAGCAAGCCCCCTCCCACGTATGAGTCGGAGGAAGAGGACAAGTGCAAGCCTATGTCCTATGAGG
+
?@@FFDFFDFHFGEIIIFIEHAGIGIIEHGGIGIIGIIGGGIIGIIIIIICGGGFH@CC@B?@<A??BBBA9?AB?CBB:@C@ACBDDDDD@CCCCDC:AC
@7SL
ACCGGATAATGACTCAGTGCTGGCAACATCAGCCTGAAGACAGGCCCAACTTTGCCATCATTTTGGAGAGGATTGAATACTGCACCCAGGACCCGGATGT
+
1=?D?DDDBFHDHGHIIEFGEGGFCFHEGIGIFGIIFGGACDGIEGDGF;BFCGIIIGCAGA@EDEEE=AD@CE@EA@DC@DDDCDDDD?B9??9@90<:
@7SM
ACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCAC
+
@@<BBDDAFFAFHGIIDHGGHG9CGCHGG<FDFD?GHGCHCH>GFFGHIG;@FG3@;=;EEE;BDEC@CCCCCBB=;5:<?C@9C@>9@@C>>CCDCCCCC
@7SN
CTGCCTGACTTCAACAAAATGTATGCGGTATATGCTCCATGGACCGTAATGTGTTTCTTCAGGAGAAAGACCATGATGATTGGGTCGGGGCCTGGGGGC
+
111+4+A3A<C,,++2A;93+,,,3,2)2)1:1:*:?<10:***)0(((/===)).))//))))((6).7.))).)..(.(6((((,,,5&)+8((&&&
@7SO
CAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATAT
+
@CCFDFD?CFFDDGGIEFDHCIIJIIIJIFIIIGGGDGFGIIGIIFIIIEHIGJIGHDHGIJJGEHFHFFCDBDECEE>5ABBCDD>CCADA:@DDCDC
@7SP
CTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTC
+
CCCFFFDEHHHHHIJJJJIJJJJJJGJIIJJJIIGIIJJIIIIIIJJJJJIJJJJIJHHHHHFEFFDECEEEDDDDDDDDDDDDCDDBDDDBDDDDDDDD
@7SQ
CTTCTTCCGACCGGGGAAATAGTTTATTTCATTGCATCAGTAGTAGTACTATTTAATTATGAGGAGAGAACTCAGCGACACTACCTGGGCCATACAGACTG
+
CCCFFFFFHHHHHJJJJJJJJJHIJJJJJJJJJJJJJJJJHJJHHJIHIIJJJJJJJHHHHHHFFFFDDEEEDDDDDDDDDDDDDDDDDDDDDDDDDDDDD
@7SR
CAAACTTATAGATATTGCACGACAGACTGCACAGGGCATGGATTACTTACACGCCAAGTCAATCATCCACAGAGACCTCAAGAGTAATAATATATTTCTTC
+
CCCFFFFFHGHFHJJJJJGGJJJJJJJIJJJJJJJJJIJJJJJJJIJJJIJJJJJIJIHIJJGHHHHHFFFFFEEEDDDDDDDD@CDDEDEEEEEFEEEDC
@7SS
GCATATGCTTACTGTATGGGACTGGCAGAGGAAAGCAAAAGGAGCAGAAATAAAGACAACAAATGAAGTTGTTTTGGCTGTGGAGTTTCACCCAACAGATG
+
CCCFFFFFHHGGHJGGIJJJHIIIJJJJJJIHIJJIIJJJJIIJJJJJJJJJJJIJIIJIJJJIJIJHHHHHGFFFDDDDADDDDDDDEDDDDDDDDDDDD
@7ST
ATTTTCTTCTGGACCTGGAGCGGCAATTCACTAACAAGAAAACAGGGAATTTTTGGGAAATATGAAAAGCCAAAATTTGTGCAGTGTTTAGCATTCTTGGG
+
CCCFFFFFHHHHHJJJIJJJIJJJIJJJJJJJJJJJJJJJJJIJJJJJJJJJJIJHHEFFFFFFEEEEEEDDDDDDDDDDDDED@CDFDDDDDEDDEEDDD
@7SU
GCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGG
+
@B@FFFFFHHDFHGIIJIGGIIGIIEIJJJJGIGGIJJIHGBGHGGIJIGIII=EGHGIHHHGHFEFFFEEEDDDDDBBBDCCCCCCDDDDDCAAACCDDB
@7SV
CTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJGFIJJJIJIJJIIJJJJGIIIJJJIJJHHGHFFFDFFEEEDEEEDDDDDDDDDDDDDDDDDD
@7SW
CTGAGATTGTTTCTGCATCTGAATCCAGAAAGGAACTAGAATTAAAACATGAAGCAGAAGTTACAAATTACAAGATAAAACTTGAAATGTTAGAAAAAGA
+
@@CFFFFFHHFD?FGIJIHIJGIIIIGHGIGGEAHIEHIGIJJJJIIEHIIJIJFIJIIIIIJGHJIJJJGHEHIIJJGHFHHFDFDFDDCCCECCCDBD
@7SX
CCATAACCCTCCCACCATTGAACTGTTGCACCGCTCCAGGTCACCTATCACGACAAATCACCGGCCTTCTCCTGACCCCGAGCAGCGGCCCCTCCGGTCCC
+
@@@DDDDAHHHHFIAFHIG<:AFHGHHHIIFHIIIIIIII>FGDCBDDHAGDFIBGAEHEEHD6>BBCC>CCCCCCCBBB<-55AA<<BBB<8<B<<BBBB
@7SY
CCAAGATTGGAGACTTCGGGATGGCCCGAGACATCTACAGGGCGAGCTACTATAGAAAGGGAGGCTGTGCCATGCTGCCAGTTAAGTGGATGCCCCCAG
+
@@@DDFFFGGHGFIGIGHBGGIIEGFHHBAHIGGGIIJJJJIJIGIGHDDE@DFEEECEEBBBBDD?ACCCDDCDACDDCCDDDDD:@A@@C@CDDB>B
@7SZ
GGGGCGGGCGGCGGTGTGGGGACGCGCTTTACGCCCGACCCGTCAGCGCGCGGCGCGGGCGGTGGTTCGCGGGGTGGCGGGCTGGTGGGACTGGGGGCAGG
+
(-(-80(0'5','&&&)+(&&(&)&&&&&((++)&&)&&)&)&((&(&&&&&)&&&&)0&&0&&&&((&)00&&&&)(&)&&)&0((+5++++(6&)&&)5
@7T0
CGGGACTCGAGTGATGATTGGGAGATTCCTGATGGGCAGATTACAGTGGGACAAAGAATTGGATCTGGATCATTTGGAACAGTCTACAAGGGAAAGTGGC
+
CCCFFFFFHHHHHHIIIIJJJJJJJJJJJJJJJIJJJJJJJJJJJIFHIJJJJJJJJIJJJJIJJHHHGHHFFFFFFEECEECDDDCDDDDDDDDDACDD
@7T1
GGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACAC
+
@@@FFFDFHFFHGIIGIIHJJJJIGHIDCHGHIJEHHGBEEHIJIJIIIJJJJIJGDHGEGGHIFDGHHEEHFDBBFDDDCEABCDDDCDDEEDDDDDDD
@7T2
CAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTC
+
CCCFFFBAHHGHH@@BHHGGGEHGIIEH<B?GHII>HHIGDBBGIGIGGG9FHGG>FG=5AEEDHIFCEHCFDFF@AEE>CCCD>CDADDCDDDDC:A@CD
@7T3
GGCAGTACTCAGCAAGGTACAACTATTCTTCAGTATGCACAGACCTCTGATGGACAGCAGATACTTGTGCCCAGCAATCAGGTGGTCGTACAAACTGCATC
+
CCCFFFFFHHGHGJJJJGIJJJJJJJJJJJJJIIJJJJJJJIJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJHHHHHHF?CEAEDBDDDDDDDDDDDD
@7T4
GGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGC
+
@C@FFFFFHHHHHJJJJJJJJJJJJJGIIJIJJIJJIIHGIJJGIJJJJJJJJJGJJEHJJIHFHHHFFFFEEDDCDCDEDEEDEDDDDCBDDCDDDDD
@7T5
CCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTA
+
CCCFFFFFHHHHHJJJJIJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJIHHHHFDBDDDDDDDDBDDDDDDDDDDDDDDDDDDDDDDDAC
@7T6
TGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCC
+
@CCFFFFFHHFHHIIJJIFIIJIJJJJIJJJIJIJJIGJFEHIJIIIFGHIJJIIIJJJJJJJJIJJHHHHHFFFFFFEEEDDDDDDDDDDDDDDDDDDD
@7T7
GGAGAAGGCAGGGTGGATCCTGATCTGTCCAAGCCTAAAAACCTTGCTCCTTTACAAGAGAGTCAGGAGTCTTACACAACTGGGACTCCCAAAGCAACATC
+
CCCDFFFFGHHHHFHIIJJJJJJJIJJJJJJJJJJGIIJJJJJJIJJJJJJIIIJJJJJJJJHHHHHHFCDFFEEEEEDDDDDDDDDDDDDDDDDDDDDDC
@7T8
TGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGAC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJIJJJHHHHHHFFFDD@DDDDDDDDDDDDDDDDDDDDDDDDDDDD
@7T9
TGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTAT
+
CCCFFFFFHHHGHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJIJJHHHHFFFFFEEEEEEDDDDDDDDDDDDDDDDDDDDDDDEDDDDD
@7TA
CTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAAC
+
CCCFFFFFHHHHHJJJJJJJJJJJIJJJJJIJJIJJIIIJJJJJJJJJJJJHIHIIJJJJJJJJJJJJJHHHHFFFFFEEEEECDDDDDDDDDCDDDDDD
@7TB
GGCATGTCTAAATCTAGTAATTTATTAGAAGCTTATCCATCCCTATTACTTTTTTAAATGGCATTAGTTCTGTGTGCTATTGGTGTTTATTTGCATCCACC
+
CCCFFFDFHHHHHJJJJGGHHJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHIGIJGHEHIJHHHHH?BEFFDEEEFEEEDDDDD
@7TC
CTGGACAGTTACCTTATTCAAACATCAACAACAGGGACCAGATAATTTTTATGGTGGGACGAGGATACCTGTCTCCAGATCTCAGTAAGGTACGGAGTAAC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJFHIJJJJJHHFFFFFEEEEEEDDDDDDEDDDDDDDDCDDDDDDBCDC
@7TD
AACCAAGCGAGAGAAATTAGAGCTGTCACAGAGACTGTCTGATCTTTCTGAACAATTGAAACAGAAACATGGTGAGATTAGTTTTCTAAATGAAGAAGTT
+
@@@FDFFFGHHHH?FHIIIJIJJJJJIIIIIGEGIIJGIIJJIIJGJIIIIGFHIHIIJJJIIJIGJGGHHG>EEDCDFFDCEEEDEEEDDEDDCDCDAC
@7TE
CAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGC
+
BC@FFFFFHHHHHJJJJJIJJJJJJJJFHJJJJJJJJJHHIJJJJJJIJJJJJJJJJJJJJJJJJJHHHHHFFFFDDDDDDDDDDDDDDEDDDDDDDDDDD
@7TF
CTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJHIJJHHHHHHFFFFFEEEEDDDDDDDDDDDDDDDDDDDDDDDDD
@7TG
TGGGAAAGGACCTAAAGGTGTATATCAAATCAGCAAACAAATCAAAGCTCATGATGGCAGTGTGTTCACACTTTGTCAGATGAGAAATGGGATGTTATTA
+
CCCFFFFFHHDFHIIIIJFHHIJIJJJJJJJIJJJJIJJIJJJJJIJHIIIJJIJJJJJJJIGHHIJIJIJIJHHHHGHDFFCDFFECEEEDDBDDEEDD
@7TH
TGGGATTCTGTTACTCTATCCACACTGCAGATTATTGGACTTGGCACTTTTGAGCGTGGAGTAGGATGCCTGGATTTTTCAAAAGCAGATTCAGGTGTTC
+
@@@DADADDDHFDDACDFGEBBDGEAH<CFB>HEGGIIG<BDDHADDAAC>D@F8@';F=F8@FECAGDC>AEA>>CDD@AA@@C;>?=>>;>AC(5:85
@7TI
CCTGAAGAGGTGGCCCGACGTTGGGGCATTCAGAAAAACAGGCCAGCTATGAACTATGATAAACTTAGCCGTTCACTCCGCTATTACTATGAGAAAGGAAT
+
CCCFFFFFGHFHHJJIJJJJIJJJJJJJJJJJJJJJJJJJIIIJJJIHHHHHHFFFFFFFEEEEEEEDDDDDDDDDDDDDDDDDDDDDEEDCDCCCDDBDD
@7TJ
CTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCAC
+
CCCFDFFFHHHHHJJJJJJJJJJGIJJJJJJJJJJIIGIJJJJGIIJIJJIIIJJIJJJGIJJIJJHFHHFFFDCDDDDDCDCDDDEEDEDDDDDDDDDDD
@7TK
CCGACGTTGGGGCATTCAGAAAAACAGGCCAGCTATGAACTATGATAAACTTAGCCGTTCACTCCGCTATTACTATGAGAAAGGAATTATGCAAAAGGTGG
+
<@?DFDDDDHFDFGGGGGIGGGIIAFDBGHAFHCHFHGAFHIGGCHIIIEAHGCFHIGHHHGCFED>CDDDDCCEDDCCAACCBBCCCC@CCEDDDDDCCD
@7TL
CAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAAC
+
@@CFFFFDHHGHDIIIIIIBHGIIIIIIGGIDHIG@FHGIIIGGGGICF@FGB@GGIIIIGGIIFHHFCECDDFD:>>CCCCCDDBDDDDDDDDDDDCCC>
@7TM
GTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTAT
+
@?@?DFFFHHHHHIIIGHIGFCHIIGIEGGDGGHIIIBCHGIGHIGGIGGC@EIIG@EEFFFFFFECCEACDCBCCCACDCDBDBDDDDDDDDEDECCCCC
@7TN
CATAAAACGACCATCACCAGCTGAAAAGTCACATAATTCTTGGGAAAATTCAGATGATAGCCGTAATAAATTGTCGAAAATACCTTCAACACCCAAATTA
+
CCCFFFFFHHHHGJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJGGHIJJIJJJHIHHHHHFFFFFDDDDDDDDDDDDDDDDDDDDDDDDD
@7TO
GCCAGTTGCTTTAATGGAAACGAAGAACCGAGAAGGGTTAAACTATATGGTACTTGCTACAGAATGTGGCCAAG
+
CC@FFFFFGHGHGHJJJGIJIJGIJGJJJJGHIGIJIDGGIIJIJJIJIJBGGIJIJJIIJIIJJHHHGHFFFF
@7TP
GCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTAT
+
C@CFFFFDHHGHHJJJJIJDHIIGIGIJGIGIGJJJGIJGHHGGGIIIGIJJJJJJGHIGIIIGJJGGHHGFHHFFFFFEDEEEDDDDDDDDDDDDDDDDD
@7TQ
ATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCC
+
CCCFFFFFHHHGFHIIJJGIIJJIJJJHGJJFIIJJJIJJJIIJJJJJJHHHIIJJJJJIIHJJIJJHHHHFDDDDCDDEDCDDDDDDCDDCDC?BBCDDD
@7TR
GACAAACTCCAGAAAGCAAGAATGCTACTCCCACCAAAAGCATAAAACGACCATCACCAGCTGAAAAGTCACATAATTCTTGGGAAAATTCAGATGATAGC
+
CCCFFFFFHHHHHJJIJJJJJJJJJJJJJJJJIJIJJJJJIJJJJJJJJJJJJJJJJJJJHHHHHHFFDFFFEEEEEEEEEDDDDDDDDDDDDDDDDEEDD
@7TS
TCTTATTCTGAACAAGGAGCACAAGACAGTCCGACTCATCTAGAGATGATGGAAAGTGAGTTGGCTGGGAAGCAGCATGAGATTGAAGAGCTAAACAG
+
CCCFFFFFHHHHHJJJJIJJJJJJJJJJJIJIJJIJJJJJJJJHHHIIGIJJHIJJBFHJJJJJJJJHHHHFFFFEEEEEEDDDDDDDDDDDDDDDDD
@7TT
CTGGAGAGAGATATGTCTACAAGTTTGTGTGTGATCCAGAAGCCCTTTTCTCCATGGCCTTTCCAGATAATCAGCGTCCACTGCTGAAGACAGACATGGA
+
BBCFFFFFHHHGHJJJJJJJJJIJJJJIJHHIJJJJJIIJJJJJJJJJJJJJJJJIJJJJJJJJJJJIJJJJJGGHHFFFFEEEEEEDDDDDDDDDDDDD
@7TU
GGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAAT
+
CCCFFFFFHHHHHIJJJIJJJJJJJJJJJJJJJJJJIJJJJJJJIJJJJJJJJJJIIJJJJJJJJHHHFFFFFEEEEEDDDDDDDDDDDDDDDCDDDEDE
@7TV
TGAGAGACCACTCTTTCCCCAAATTCTCGCCTCTATTGAGCTGCTGGCCCGCTCATTGCCAAAAATTCACCGCAGTGCATCAGAACCCTCCTTGAATCGGG
+
CCCFFDDFHFHHGJJJJJJJJJJJJJJJJJJJJJJJIGIHIGIFIIEHIJJJJIIJJFFHHHHFFEFEEEECDDDBCCDEDDDDCDDDBDDCCDDDDDDDD
@7TW
CCAGTGTGCCTGGAGTAATAAAGGAGGGAGGGCAGCTACACCAAAGGGTTCCTTGCCAAGTGGAACATCGCCGCCTAGGGCTACAGCTTCTTCGTTGACAT
+
11+22<?+<?+?7<;2++<<,++3+32:)1?:A?8;000==*0=2))(.(.7)).).=3=).=))....(,',2;'',+((+(3(((+33(88(+8;(++:
@7TX
ATATAAACACAATAGAACCTGTCAATATTGATGACTTGATTAGAGACCAAGGATTTCGTGGTGATGGAGGATCAACCACAGGTTTGTCTGCTACCCCCCCT
+
=;++==AD<DFFBB<4AFE@GHFC4C4C><F?FFEF@<B>D@94*B9?BBFC9*9BBF?C6.5@F>3C=1;7?A:=25;((.6>A((-5@@>::9?5/&5&
@7TY
GGAACAAGATAAAAAAGTAGAAAACTCAAATAAAGAAGAAATACAGGAAAAGGAGACAATCATTGAAGAATTAAACACAAAAATAATAGAAGAAGAAA
+
;;?D??DD?FDFADE:@2<AAEEF?CGA?C??CBCFGE;0009BDBF;;;;BB@A@@F@F@DEIE>?CCEFFDDB;;@CCC?=5555;5:>AABBBBB
@7TZ
ATCTCCTGTGACTCTCACCTCTCAGACAACTAAGACAGATGACCCCCAATTGAAAAGAGAAATAAGGTTAATGAAAAACAGAGAAGCTGCTCGAGAATGTC
+
CCCFFFFFHHGHHJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJHIIIJIIHIIJJJJJCHHHHHHHFFFFDEEEEDDDCDDDDDDDDDDDDE
@7U0
TTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGG
+
CC@FFFFFFHGHHJJJJJJIJJJJJJJJJJJIJJJIJJJJJIJIJJJIG;BHGHHHHFFF@DDEEEEEEDEDCDDDDDDDDDDDDDFDDDDCDDBDDDDDD
@7U1
TGGAGCCTTACAGTTGGCAAGTCCAGGCACAGATGGAGTACAGGGACTTCAGACATTAACCATGACAAATTCAGGCAGTACTCAGCAAGGTACAACTATTC
+
<?@BD8DDDFF?AGF<:ABFE<BHFFE@EFB@G?9??CDDF99?BEEEFEFFEFFIF@)==77CFFECEFIFAAEE=?BBD7@A;66@B?5@>AB>BBBBA
@7U2
AACAGATTGTGCAAAAGAACCAAGAAATAAAAAACATGAAATTAGAGCTGACTAATTCTAAGCAAAAAGAAAGACAGTCTTCTGAAGAAATAAAACAGTT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHFFFFFEEEEEEEDDDDDDDDDDDDDDDDD
@7U3
TACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJFHIJJJHHHHH@CEFFEEEEEEEDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDD
@7U4
GGGAGCCCTGCCCCAGGGGCCCATGCAGAATGCCACCAAGTATGGCAACATGACAGAGGACCATGTGATGCACCTGCTCCAGAATGCTGACCCCCTGAAGG
+
C@@FFFFDHFHHHJJJIIIBGAGHGGGGGGIJJJGIEDFHBFGDHIJIJJEIGGHIJCHEHFFFF;BACCAACDDDD@CDCCDDDCDCC@CDDDDBBDDDD
@7U5
CATCAATGAGCTGTGTTCTCAGAAGGCCTTTGTCTCCAAGGTGGAGGCTGTCATTCACCCCCAATTTCTGGCAGATCTGCTGTCCCCAGAAAAACAGAG
+
?<??DD>;222<DEECEDFF<F3A?E+22CFC:9<??C**1?@?D=D;0B?8BBB*8./('-;CD@C7.7777???;?:@;;6;>A?;;=>>???=95(
@7U6
AAAGATGTCATCATCAACCAAGAAGGAGAATATATTAAAATGTTTATGCGCGGTCGGCCAATTACCATGTTCATTCCTTCCGATGTTGACAACTATGATG
+
@@<DDA;BFFFFAE>BGEGEG;F@A><CFHGGCHHBFHGH4914BF*:?D@FB@BEBEBBE@D@CC>CCACC3;B>BCCC>=8?:2>CCCCC?@@@C@>A
@7U7
TACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTC
+
CCCFFDFFHHHGGIJJIJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJIIJJJIJHJHHHHFFFFEEEEEEDDDDDDDDDDDDDDDBDDDDDDCDDDD
@7U8
TTATTTGCATCCACCTGTCCAGTTGCTCTGCTGTCTTGTGTTTTTGCAGCCTCTACAACCCCACGTCAGAGTGTGGGATTCTGTTACTCTATCCACACTGC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJIJJHJJJJHHFHIJJJJJJJJJJJJJJJJJJJJJJIHHHHH@DCDFDCDEDDEDDDDDDDDDDDDDDDDDD
@7U9
TGCTAATTTACAACAAGCAAGAAGAGAAAAGGATGAGACAATGAGAGAATTTTTAGAGTTGACAGAACAGAGTCAAAAATTACAGATTCAATTTCAGCAAT
+
CCCFFFFFHHHHHJJJIIJJJIIIJJHIIJJJIJJJJJIJIJJJJJJIIIJJJJJJIJFHIJIIIHJJJJIDCEFHHFFFFFEEDECEDDEEEDDEDDDDD
@7UA
CGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGC
+
@@@ADDDDHHFHHDHGII@GGDHIIIIIIIIIGIIIIIIIIGHHIGIIIIGFFCHIGEEDECGCEEHHFEEE?CDCCCCCCCCCBCCACC?BCBBBB>@B
@7UB
CATCAACCTCTCTCATCGGGAAGACCTGGCTTACATGAACCACATCATGGTCTCTGTCTCCCCGCCTGAAGAGCACGCCATGCCCATTGGGAGAATAGC
+
CCCFFFFFHHHHHJJJJJJJJJIJJJJJIJJJJJJJJJJJJJJJJJJJJJIIJJJJJIIJJJJJHFFFEEEEEECDDDDDDDDDDCDDDDDDDDDDDDD
@7UC
ATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCT
+
?1?=;D?DBDFFFFDFGBHHABBEEBFF>9:??:??F@DF@@F3BFBBFBFIFACFC7=CEFA==<B8/?;>(5@>:A?9?1<??14@B>BA>(::AABB3
@7UD
GTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGC
+
CBCFFFFFHHHHHJJIJJJJIJJJJHIJJJJJJJJJJJJJJJJJJJJJJJJJGHHHHFDEFFFEEEEEEDEDDDDDDBACDDDDDDB@DDDDDDDDDDD
@7UE
CAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCC
+
CCCFFDBDFBFHHDAFHIGIIIIIIIIIIHGHHGGHHIGGHGIIGHIIIICHHGHIIHGEBEDFDBEDEEDDDDDDDDDDDDDCCDDDDDCDDDDCDD@DD
@7UF
ACAGGAACCCAGAGATTTTGCATATGACTCAGAAGTGCCTAGCTGCCACTCCATTTATATGAGGCAAGAAGGCTTCCTGGCTCATCCCAGCAGAACAGA
+
;?@DDDDDFHDHHDHEHFFE?HDB?AFHIIDFGG;9?DHAH;D?GDHG>ADHFDGEHCBCBGHG;FGIGIG@C>CCEEEEBDAA@CA5@;55=CC5?9A
@7UG
GAACCAACAGCACATCGCCGAACCTTTGACCCTACACAGGGAAACCCATTCAGGGTTCTAGGTGCTGGTGATTCCGTCAGACCCGATACGGCCTCATCTGG
+
0;;1(((-(294(2))823(8((().))0))()0(0=)(((-(..((-))).8)()(())8).(((((,(--6(-((,(',,((5&&&&++&&&++:((3:
@7UH
CAAGCCTATGTCCTATGAGGAGAAGCGGCAGCTCAGCTTGGACATCAACAAGCTCCCCGGCGAGAAGCTGGGCCGCGTGGTCCACATCATCCAGTCACGGG
+
??<;;D:3AADDEE>BBA4:+ACFFD6)1:61?DDBDAE919B<BCC9=;@7@=@=;A:<<?63=83>:(+2<?&90)&&23(4:4:A>>>>:++((40;5
@7UI
AAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGG
+
@B@DDFFFHHHHHJJJJJIGIJJJJJJJIJJGIIIIJJJJJJJJJIJJIJIJJJIJJJJJJJHHGHFFFFCEEECECECDDDDDDDDDDDCDDDDDDDDDD
@7UJ
CAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACC
+
CCCFFFFFHHHFHJIIGIJJJJJIJJJJIJIIJJJJJJJIJJIIJJJJJJJJIJIIJJHHHHHFFDFEEEEEDCDDB=BCDDDDDCDD:ACCDDDDDEEDD
@7UK
CTTTGAACTCAGGGACACCACCAGCTATTGGACCTTACTATGAAAACCATGGATACCAACCGGAAAACCCCTATCCCGCACAGCCCACTGTGGTCCCCACT
+
@@<;DDDBDDA?FI1AEC;<:<FFE<?4CF@GICBG>GIGE??D?BBB?<?D<FFCC8<;F8;:=?;B?CC;@BBBB@;8;=((<B<?B::@(++:<@?B?
@7UL
CCCAGGCCTCCCATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGAT
+
==114BB:DDD+2223<+ABF9EDEECCEEE9EEDDE99?DDDIID3D?/?983?B@B<BDDD;;AC@>?C>?@AD=;@>>(555-;3>>A????>.;??4
@7UM
TTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACAGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAACAGCTATGGGCAGCAGC
+
(;;?==844)).28)2:>)=);.2.).3:944)-6:@)9((<(0(9))9=).))08))99513.36;81==8>1).998);/=(6(3937((-((75;(,7
@7UN
CCTGATGTGAACCTTATTGGGGAGCATTCTGATGCAGCAGAGCTTGGAAGGATGCTTCAGCTCATCTTAGGCTGTGCTGTGAACTGTGAACAGAAGCA
+
@@@DFFFFHHHGHIIIIIGGHG@FIEHIIIIGJGIIJJIJFIGHHIHJHIIJIJIGHIIGGEHGGIG@CHGCFF@DFFF>CEDEED>ACDCC?A>A?C
@7UO
CAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATG
+
=;?DD?DA?A?D::<ACDCH3EF=1<+C;8):C?>DG@GB;F*?4?FF@DD@B;;==F;4@@D=CC3=;=;3;?>>(;@>;3@B>=3(9<22;B<A>>>@+
@7UP
CTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGC
+
CCCFFFFFHHHGHJIJIJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJIJHHFFEEEEEDEEDEDDCDDDDDDDDDDDDCD
@7UQ
CTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGT
+
CCCFFFFDHHHHHGIHIJIJJIJJJJJJJJJJJIGGIJJJIJJJIJJJJJIJJIJJJJJJJJJJIJJGHHHHFFFFFDDDDDDDDDDDDDDDDDDDDDDDC
@7UR
CACAGATTTCGCCGCCAGCTTTCTGAACCCTGTAACTCCTTTCCTCCTTTGCCGACGATGCCAAGGGAAGGACGTCCTATGTACCAACGCCAGATGTCTG
+
CCCFFFFFHGHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIIIIHFFDDEEEDDDDDDDDDDDDDDDDDDEEDDDDDDDDDDDDEDED
@7US
CCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACAC
+
@@CFDFDFFFHHFFHJJIJGHFHIJJGIHIJJIIIGGIIIGGJJJEIIJIDHIJJJJEEHHJJGHHHHDFCDEFFEDEEDEDDDCCCCCCCDCCDDDDDDC
@7UT
CTTGTTTCCATCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCC
+
CCCFFFFFGHHHHIJJJJJJIIJJJIIIJJJIIIIJJIIJJJJJIJJIJIJJJJGJJIHIHHHHHFDFEFDEEDDCDDDDDDDDEDEDDCDDCDDDDDDDD
@7UU
CAAAAAGAATAATCCTATAGCAAAGAAGGAGCCACACGACAGGGGTAACCTGGGGCTGGAGGGAAGCTGTACTGTCCCACCTAACGTTGCAACTGGGAGAC
+
@@CFFFFDDHGDAGGAHIGIIDHGIEEGEGIIICDDDG@FHIIEG7@FEGIEGGEEEHDBECD@DBDCC>CCDCCCDDCABDDDDD<CBD>C>CDCBB?@B
@7UV
GGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCAC
+
@?;1D8DDB@FFDGIEBE<:E?EEGFAF?B*?BFFG;?D8?D<;=BBFFFF9;@D;CE;E3AEEED@@?7(9@A@::A??<<7??4:>A>99@&):((+9>
@7UW
CCAGAACATTGTTCGCTGCATTGGGGTGAGCCTGCAATCCCTGCCCCGGTTCATCCTGCTGGAGCTCATGGCGGGGGGGGGCCTCCAATCCCTCCTCCC
+
@CCFFFFDHFHDDGEH>EEIIBEGGH?CGGHHGHIIIIIIGGHIIGHIGEHHEHFEDDDF@A@ECBCDCCCB@B5><>-900908(3((+9+:(8(39+
@7UX
CTTCATGAAGACCTCACAGTAAAAATAGGTGATTTTGGTCTAGCTACAGAGAAATCTCGATGGAGTGGGTCCCATCAGTTTGAACAGTTGTCTGGATCCAT
+
@@@DDD<;BFFFBBB2?D<CFEHIIEIFFBE9:CFFGAGCEFC>DGIIIA9BGFDGAFIDCFF>A)@FE5CCE>?7;@7ADBDCCB@CB>@BBA?BAB?BA
@7UY
ATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCC
+
@@@DDDDDDHDBDFEEEHD?DG>CH@BHI>CFC?CDGEGG;?D?FBFHI=BGBBFGG@H>38@>>DD==EA?AB>8>C@CCC?A>>:@>>ACC>(2<ACA8
@7UZ
AGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGAC
+
@@@DFFFFHGHFHJIIIJJJJIIJJJJJIIIIIIIJIJJJJIIJIJJIJEHIIJIJIGIJJJJJIIIJHHHHFFFFFDEDDEDDDEEDDDDDCDDDBDDDD
@7V0
TCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGC
+
===;=BDDFD2CFFEBAGBE3FEGIBCCBCFF=DBBF=F;;).8)).7@>@EF>;77.7?7;..(.6;;(5;5;=?<(5>AB@?<?B024:?B@?9<>@(:
@7V1
CACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGAT
+
CC@FFFFFHGGHHIJJJJJIJIIJJJJJIIJJJJJIFHIJJJJJJFHHIJJIIHGJIIIJJJHHHGFFFFEDEEDDDDDDDCDEDDDDDDDDDDDBDDCDC
@7V2
TGGACAACATGATCCGCCGCCTCTCCCCGGCTGAGAGAGCTCAGGGACCCAGGCCGCACCAGGAGAACAACCACCAGGAGTCCTACCCTCTGCCAGTGTCT
+
;=7AAAAA8;=AB,+212)):?ABBB>A<:<0A.7ABAABB3A.)(1;;=@=;;@6=:===9;081(3(89+(9;29;9938:3::9;3833(5+5(++(+
@7V3
AGGAACCCAGAGATTTTGCATATGACTCAGAAGTGCCTAGCTGCCACTCCATTTATATGAGGCAAGAAGGCTTCCTGGCTCATCCCAGCAGAACAGAAGGC
+
@@@DFFFDHFFHHIJJJIHDHIIJFHHEHIIJJCGGDEGGGEHJIEEEHI@HIJEIIIIEGGIIIIIGGEBEEHFHEFFFFFEEEDEEDCBDDDDCDD:??
@7V4
CAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACC
+
CCCFFFFFGHHGHIIJGHHIGIJGHIJJHIIIGIIJIGIJJJIJGHGGJJJIGGGIIIHHHHHFFFFEEEEEDDDDDBDDCDDDDDDDACDCD@CCDDDCC
@7V5
GAAAATATATTTTTCATCATTGTGCTTCTCCTTATTTTAATTAATGTGCTTCTTCTTTTAGATACCGGATAATGACTCAGTGCTGGCAACATCAGCCTGA
+
C@CFFFFFHHHHHJJJJJIJJJJIJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJIJJJJJJIJJJJJJJJJIIHHHHHHFFFFEEEEEDDDDD
@7V6
CTCCCCAGCCCTCTTCACAACCTCTCCAAATACACAGACAAACTCCAGAAAGCAAGAATGCTACTCCCACCAAAAGCATAAAACGACCATCACCAGCTGA
+
CCCFFFFFHHHHHIJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHHFFFFEEEEEDDDDDDDDDDDDDDDDDDDD
@7V7
GAAAGCGAGAGGGAGACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGC
+
===AA>=+7)0?=)?)<AA4?A<?AAA)7=BAAAAA=AAABA<AA@5=>>>>>@===;=8;8;;;;??????=???=?8;??<9<?;??=?559;;=7;=<
@7V8
CTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGC
+
CCCFFFFFHHHHGHHIJJGJJJIJJJJJJJJJJJIJJJJJJJJJJJHIJJJJHHHHHHFFFFFDDD@CDDDDDDDDDDDDDDDDDDCCDDBDDDDDDDDD
@7V9
GGAAAATGAGGACCTCAAACAACAATGTATTCAGCTAAATGAAGAGATTGAAAAGCAAAGGAACACTTTTTCATTTGCTGAAAAAAACTTTGAAGTTAACT
+
@@@FFFFFHHGHHJGGGIJIGEGIFIGHHGGIIGHIGHIIICHHFGGGHIIJIJCGIGGIJGIHGIIJJIIIAEHGHHGHFFFFFDDDDDDDDDDCCDEDD
@7VA
CCAGGACTGCAACTCGGTTTTCCAGGCATTTCACATATTCTTTCTTCTTTCTGCGACATTCTCGAGCAGCTTCTCTGTTTTTCATTAACCTTATTTCTCTT
+
11=BD?DBFDFDFFBGFFGEFEIHHE;?:EDCFGF>GDFFFFIIIIFFBFFFIIF@FFIIDFEEIFEF@DDDB>CCC;AC?B?;>BBBBBBB:ADEADBBB
@7VB
CCAGATAGCAGCTACCCCATGGACCACAGATTTCGCCGCCAGCTTTCTGAACCCTGTAACTCCTTTCCTCCTTTGCCGACGATGCCAAGGGAAGGACGTCC
+
CCCFFFFFGHHHHJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJHHHHHGHFFFFFFEEEEEEDDDDBDDDDDDDDDDDDDDDDDDDBDD
@7VC
CCAGCATCCACTGCACCTACAAGGATGGAGTACACGATCAACAGCTCACTGCAGCCTTCACCTCCCATGCCCCAGCAGTCCTCCCACCTCAGTCTTCCA
+
C@CFFDFFHFFGHGIJHIJJIJGGIJIJGI?EFHGIIJDHIGIGGIJEIJJIDGGIIJIIJJIJIJHDEFHFFFDEEEEDDDDDDDBDDDDDCCDEDDD
@7VD
TTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGG
+
@CCFFFFFHGHHHGIIJJJJJIJJJJIJJJIGIJJJJJIIIIJJJIJJJ@EHGEHCHFFFCDDEEEEEE@CCDCDDBDDDDDDDCDFDDDDDDDBDDDDDD
@7VE
CAGACTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCG
+
=?;+4ADD:AA;CDFF@9@3+:??:;;EEF@>?D<:9?FFGBA;F;BFAFFF=C@;@FEA;CF:7)-5?).7376(;(;>;?>@8287(+(+4>3>::>@?
@7VF
GTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCC
+
@@BDDDDDHDFDHIEHGIIGIIIJJGGGGGIIGGGIIGIIIIJDGHIJIGIHGIJJJGIJIGGIIJIGHFHEACFFFDEDEDDCACCCCDABBDDDCDD
@7VG
AAAGCCTACAAATTTATTAAGGGAAGAAGAATTTGGTGTTGATGATTCTTATTCTGAACAAGGAGCACAAGACAGTCCGACTCATCTAGAGATGATGGAA
+
@@@DFFFDADFFDHJJFIIGHEHGGICFHBFHIFGIFFHGIGGIJJIJIIJDG>GHGG@EEAECDFGGGIIGFFHHHFFFCDDDDDDACCC>@>@BCDAC
@7VH
CCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGT
+
@?@?DDDD?:2CDBEEBG?FB:FBBBCB@EGIIIF?;;F@BBFBEFB?FF@398CGEEE9@ACEABBDB>BCCEA>A@B@B;ABB:A>8?<@??8+28>8@
@7VI
GTATCAGATCCTGGGCCCGACCAGCAGTCGCCTAGCCAACCCTGGAAGCGGGCAGATCCAGCTGTGGCAATTCCTCCTGGAGCTGCTCTCCGACAGCGCC
+
@?@DDDFFGFHHHHBEGHIIJJJJJJJECDEIIHIIJJJJIIJIIECGGHBEDDDDDDDCCC@CDCCBDCC@@CCCCCCDB?CACCCCCCCB>DDDDDDB
@7VJ
CAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAAC
+
CCCFFFFFHHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJIJIIJJJJJJJHIIJJJJJHJJHHHHHFFFFFDDEEDDDDDDDDDDDDEEDDDDDDDDDDDD
@7VK
ATTTGAAAGCTGAGATTGTTTCTGCATCTGAATCCAGAAAGGAACTAGAATTAAAACATGAAGCAGAAGTTACAAATTACAAGATAAAACTTGAAATGTT
+
CCCFFFFFHHHHHJJJJJJJJJIJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJIJJJJJJJIJJJJJJJIHHHHHFFFFFFEEEEEEDDDFE
@7VL
CCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAAC
+
CCCFFFFFGHGHGIJJJIJJIIJJEHIGIFGIIIGGIHJJJIIJGIIJIIGGGGGIJJIICHHJIHGHB@DCEDCEEEECED@CCDDDA@ACDDDDDCDC
@7VM
CTTCAGCTACTTCTCTGCCACAAACTGTGGTGATGACATCTCCTGTGACTCTCACCTCTCAGACAACTAAGACAGATGACCCCCAATTGAAAAGAGAAAT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJHIIFHIJJJJJJJJJJJJJJJIJJJJIJJIJJJJJJJJJJIJJJJJJHHGHHHFFFDDDDDDDDDDDBCDDDD
@7VN
CTCATCAGCTCCCAATGTGCATATAAACACAATAGAACCTGTCAATATTGATGACTTGATTAGAGACCAAGGATTTCGTGGTGATGGAGGATCAACCAC
+
@@<BBDDBF?FHBFFGC?C9FEHGBHEHG?FCDEGHBFHAGIIB<<DFH9<GCGGHG3/9B@A>FGGHC;@E;EA=)?=C>6?3;>CCBA?CCA@CB8(
@7VO
GCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACC
+
@@CFFFFFHHHHHJJJJJIJJJJJIJJGIIJJJJJJIIJJJJJJJJJJJJJJJJIJJJJIIJIJIHHHHFDFFEEEEEEEDDDDDEDDDDDDDBDCDDDD
@7VP
AGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACC
+
CCCFFFFFHHGFHIIIJJIJJJJJJGIJIIJJJIIJJJJJJJJJJIIJJJJJHHHFFFFFEEEEEEEDDDDDDDDDDDDDDDDDDDDDBDDDDDEDDDDDD
@7VQ
GAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGT
+
CCCFFFFFHHHHHJJJIIJJJJJJJJJIIJJJJJJJJJJJJJJJIJIGIJJIIJHHHFFFFDDEEDDDDDDDDDCDDCDACDDEDDDDECDEDDDDDDDC
@7VR
TTTCAAACAGTCCAGGCCCTCCGAGGACGGGCTGCATAGGGAAGGGAAGCCCATCAACCTCTCTCATCGGGAAGACCTGGCTTACATGAACCACATCATGG
+
;?<;D;DDHHHAB@GBFACCE@FEDAGBHBDH?@CFBFHCG@=;@AHHE=???;@A@6;>?C;>AC@>:6=85<8ACCCB?38>>CACCCC?B<8>@::AC
@7VS
CTTCATTTGCAAAGAATAAATCCAACTACAGTGAAAATGAAAAGTTCTGTCTTTGATGAAGACAAAACTTTTGTAGCAGAAACATTGGAAATGGGTGAGGT
+
CCCFFFFFGHHHHJIGHGIJIJJJJIJCGIHEHHIJJJJJJIEGIIJJIIHIJJJJJIIJJIIJJIGIIJIJIFHIIJIJHHHEEHDFFEDEEEECDDDD>
@7VT
CTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCT
+
CCCFFDFFFHDHHFHIIGIIIJJIHIIJJIIIICDHIIIIJI?FGGIJJIBGHGIGIEIIJIHFHFBDDEEDDDBDDDCCDDDDCBDDDDDDDDDDCCCDD
@7VU
CCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGAAACTACAGTTATCCCCAGGAACCTGGGAGCTACCCCATGCAGCCAGT
+
@<=DD8ADBFB8FEHEH@FB?DABB<DB08?)BFHII>FEDEFG<F@@C=177).=?;>??C;>66;@ABC=B(9<?A9?<?052>AAAB??9>>>ABA(4
@7VV
CGATGCCAAGGGAAGGACGTCCTATGTACCAACGCCAGATGTCTGAGCCAAACATCCCCTTCCCACCACAAGGCTTTAAGCAGGAGTACCACGACCCAGTG
+
CCCFFFFFHHHHHJJJJJJJJJJJIJIIJJJJJJJJJJJIJIJJJJJIJJJJJJJJJHHHHFFFFFDDDDDDDDDDDDDDDDDDDDACCDDDDDDDDDDCD
@7VW
CGATGCCAAGGGAAGGACGTCCTATGTACCAACGCCAGATGTCTGAGCCAAACATCCCCTTCCCACCACAAGGCTTTAAGCAGGAGCACCACGACCCAGTG
+
?8:=AD:=DDDC<A2:+<31<EEI*C911?DEBD6?DDDBD?B/888B@ADC@@@ACCC?C7@D;A@?;??;9;;9>:A55(,518(+<>(280))0<?4>
@7VX
GGGCTATTCCACAAAGCCACAACTGGCTATTGTTACCCAGTGGTGTGAGGGCTCCAGCTTGTATCACCATCTCCATATCATTGAGACCAAATTTGAGATG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJFHJFHGIJJJJJJJJJJJJJJIJJJJJJHHHHHFFFFFFFEEEEEDDDDDDDDDDEDDDD
@7VY
GCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGAAAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACAGCAACCTATGGGC
+
1=+222222AC;A;22+<33+22+@)11@BBBB7*0*:*00000*/**/=.>.=5-.>=)..)7>3).=).;@3(,.;6(-(-,5,((55;9955(+(+(
@7VZ
CACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGAT
+
CCCFFFFFHHHHHJJJIIIJIJJJIJJJJJJIJJJJHIIJJJJJJGHIJJJJIGJIIIJJIJHHHGFFFBEDDEDDDDDDDDEEDDDDDDDDDDDDDDDCD
@7W0
CTACTGTAGAGCCCACACCTGGGAAAGGACCTAAAGGTGTATATCAAATCAGCAAACAAATCAAAGCTCATGATGGCAGTGTGTTCACACTTTGTCAGATG
+
CCCFFFFFHGHHHJJJJJJIIIIHIJJJIJJIIIIHJ?FFGIIJJJJIGHHIIJJJFIJJJJJJJJIGJHGHHGHFFFF?@;@@CDEDDDDDDDCDEDCDD
@7W1
CTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACT
+
CCCFFFFFGFDFHJJJJJJJJIHHGIJIJJJJJJIJIJIIJJIJJJHGIJGGIJIJJGHGFFFFFEEECDD;@CCDDDDDDDACCDDCDDDDEDDDDDDDD
@7W2
GCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGT
+
@CCFFFFFFDFHHJIIIJIJJGIIIJJIIJJJJGGHGGGGHHGGIHIGHFHIJIJJGHHIIGEEIIGIHHHFFDEDDEDDDDDCDCCDDDDDBDDDDDDC@
@7W3
CTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCT
+
C@@FFFFFHHHHHJJJJJIJIJJIIIIGIIJIGGH?FHJJJGHGIJ=DHIJJHHHHHHFFFFFDEEEEDDDDDDDDDDDDDDDBBDDDDDDDDDDDDEDDD
@7W4
CGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCT
+
CCCFFFFFHHHHHJJJJIJJJJHHJJJIJJJGHIJJJJJHIJIJJJJJJJJJJJJIJIJJJJJJJIHHHHHHFFFFDDDDDDDDDDDDDDDDDDDDDDDDD
@7W5
TCCCCTCAGTCCTCACCATGCCTCAGGAGGTCAGGGCAGCCAGAGAGCATCCCACCTGCTCCCTGCTGGAGCAAAAGGCCCCAGCAAACTTCCATATCCTG
+
CCCFFDDBHFHHHJEGIGCHIIHIJJJJJJFGIJICHIIGIJIJHEFGIIGIJJJJJEIIIHHHCEFFFFEEDEDCCDBDDDDDDDDCDCDCDDDDCCEDD
@7W6
AAAAATAATTCTGTGGGATCATGATCTGAATCCTGAAAGAGAAATAGAGGTTCCTGATCAGTATGGCACAATCAGAGCTGTAGCAGAAGGAAAGGC
+
=@<D?D:?C<DBF2<:1?FFFHFE<FHF+9FHFIFFFBD;399BD<FFFFFFFFDC@89B=F8=CECFGFICEE==AEEEC;?@DBD;;@A@9?2;
@7W7
CAGAAATCTCCAGGACCTCAGCGAGAAAGGAAGTCATCTTCATCCTCAGAAGACAGGAATCGAATGAAAACACTTGGTAGACGGGACTCGAGTGATGATTG
+
@@@DDDDDHAHBCEFGE@CFB@G?CEE@?DGH;:?FDFHHI>9BGIE88??FCEG@=2CHEE@DEFHHFH?DEB@@C;@366988'29A?59:?::>:@CC
@7W8
CCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCT
+
CCCFFFFFHHHHHJJIJJJJJJJJJJJJIFHIJJIJJJIJGHIJJJJIJJJJGJJIIJIIJJJJJHHHHHHFFFFDDDDDDDDDDDDDDDDEDDDDDDDDD
@7W9
GAAAAACAGGCCAGCTATGAACTATGATAAACTTAGCCGTTCACTCCGCTATTACTATGAGAAAGGAATTATGCAAAAGGTGGCTGGAGAGAGATATGTCT
+
CCCFFFFFHHHGHJJJJJIJJJJJIJJIJJIJJJIJIJIIJJJJIIJJJJJJJJIJJIJJJJJJJJFHHHHFFFFFFEEDAC@DDDBDDCDBBDDDECDEE
@7WA
CATAAGTCATCAGAACTACCTTTACACATCCCTACACCAACCATTGAGCTTAAGAAGACATTACAATTATTTCCTTAAACCTATTGGGTGGACCGTTACCT
+
00(-()))).42)).2<).26=)).;)6)2)(2=13)81(((()0006)))))))06))))))))/<)))).)))).;=)..))..)(79',-,'3262((
@7WB
TTAAAACATGAAGCAGAAGTTACAAATTACAAGATAAAACTTGAAATGTTAGAAAAAGAAAAGAATGCTGTGTTAGACAGAATGGCTGAATCACAAGAAGC
+
CCCFFFFFHHHHGIJJJJJIIJJJJJJJJJJJJJJJJJJJJJJIJJIJJJJJJJJIJJJJJJJJJJJJJJEHJJJHHHHHHFEFFFEDEEEDDDDDDDDDD
@7WC
CAAGTGCAAGCCCCAGATGAATTACGACAAGCTGAGCCGGGCCCTGCGCTATTACTATAACAAGCGCATTCTGCACAAGACCAAGGGGAAACGGTTCACCT
+
@CCFDDFFHHHGGJJJIIIJJFIIDGIIGIJBHIHHIJJJJIJJJIGIHHEFFFFFDEDEAEDCDDBBDDCA@CDDDDDDDDDDDDDD@@DCDDBBDDDDD
@7WD
TCTCACCTCTCAGACAACTAAGACAGATGACCCCCAATTGAAAAGAGAAATAAGGTTAATGAAAAACAGAGAAGCTGCTCGAGAATGTCGCAGAAAGA
+
CCCFFFFFHHHHHJJIJJJJJJJJJJJJJJJJJJJJJJJIHJJGIIIGIJJJJJJFHIIJJJJJJJJHHGHHFFFFFEEEDBDDDDDCDDBDDDDDDD
@7WE
TATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCC
+
@@@DDBBDB<DHD@ACDEHDHCGBHIG?FHDHII@GEB;?C6?DHIIIG3=BFHGGGGIIIGH;E;CC?@DDFFACCECEBA5;CCBCCCCCB?CB7?BAB
@7WF
CCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACAC
+
@@@FFFDFDAHDHIIIIIEGHGHBFFHHIGIIGFIHIGIIIIIIIIIIGEGGIEEHGGEEFGGBEHEH;@DFFFDEECEEACCAACCCCDDDDDDDDDCDD
@7WG
GTTTGGCTTTTCATGGCCTGCCACTGAAAATCAAGAAAGAACCCCACAGTCCATGTTCAGAAATCAGCTCTGCCTGCAGTCAAGAACAGCCCTTTAAATTC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJHJJJJJJJJJJJJJJJIJJJHHHHHHFFFFFEEEEEEDDDCDDDDDDDDEED
@7WH
CGCAGACGGAGCAGACAAATTGGCAAGCCCCCACATTTCGAGCAGTTGCAGAACCTGGCATACAGCACAAGGGTGTGAAGAGTAAGACAAGTTCCCGTG
+
-(75>-.53(((.)=@1)2.@):)=3??(((0(7(=?3).(;499>?1=1=;)8(8>77=)).)6((((9973((,7557((,5((+(5+(5(8((&()
@7WI
TTTTTGGATACCAGAAACAAGTTTCATACTTACTATTATAGTTGGAATATTTCTGGTTGTTACAATCCCACTGACCTTTGTCTGGCATAGAAGATTAA
+
CCCFFFFFHHHHHJJJIJJJJHIJJJJJJJJJJJIJJJJJJHIJIJJJIJJJIJJJIJJJJJIIIJJJJIIJJJJHHHHGHEFFFFFEEEEEEDDDDD
@7WJ
CGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCG
+
???:BD@DBCDADII@E1C@@C:?DDDADD@DDDDB<CDDIAACD;ADDDDDAADD>ABAAA;;AA?=<>AA>AA9??9>>??>????A>+>AAAAAA>A>
@7WK
CTTTTCTCTTGGATATATGCCATACCCCAGCAAAAGCAACCAGGAAGTTCTGGAGTTTGTCACCAGTGGAGGCCGGATGGACCCACCCAAGAACTGCCCTG
+
CCCFFFFFHHHHHJJJJJIJJJJJJJJJJJJIJJJJJJJJJIJJJJJJJJJJIHIIJJIIIJJJJIHIJIHHHHFDDDDCDDDDDDDDDDDDDDDDDDDDD
@7WL
GCTTTCCCCCTCCTCTGATGATTAAACAGGAACCCAGAGATTTTGCATATGACTCAGAAGTGCCTAGCTGCCACTCCATTTATATGAGGCAAGAAGGCTTC
+
;?8B:DD???C?BDGEEF>?CH@AH<+CGI;?F?FBGDF99DD>9DGBD49?D<=<<3)8/=)..7C==)=E7?7;;;;;;;6;;;;@ABB?7?95(555,
@7WM
CCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGG
+
?@@ADFADDFBCDBF?B@HIIGIIDIGDEG>HGI=DHIIIIIIIIIICFHEHIGIGHFGEHEDDFBECCE>CCC?CBBCB9>@CCCCBBBBB@AAB@CC?C
@7WN
CCAGGACCTCAGCGAGAAAGGAAGTCATCTTCATCCTCAGAAGACAGGAATCGAATGAAAACACTTGGTAGACGGGACTCGAGTGATGATTGGGAGATTCC
+
CCCFFFFFHGHHHJJIJJJJJJJJGHIJJJJJJJIIJIJJJJJIJJJIJJJJJJJJIJJJJIJJGHFGEHFDEFDDADBDDBDCDCDDCDDDDDDDDDDCE
@7WO
GCTTACTGTATGGGACTGGCAGAGGAAAGCAAAAGGAGCAGAAATAAAGACAACAAATGAAGTTGTTTTGGCTGTGGAGTTTCACCCAACAGATGCAAAT
+
@@@BBBDDD:CD8>@GGA=FHEC;7FGDAC>AHF>1:?)??D>GGBFF94)8CDHC@@@@GD@EH@A?>?63;?>A@C?;;>ADC(5??(8,::((>@C:
@7WP
GATGACCCCCAATTGAAAAGAGAAATAAGGTTAATGAAAAACAGAGAAGCTGCTCGAGAATGTCGCAGAAAGAAGAAAGAATATGTGAAATGCCTGGAAA
+
@@@FFFFFHGHHHJJHIIIJHGHIIJJIIJFHIJJJJIJGIHHGHIIJJIIJJIJJJJIIIJGHHHFFFEEECCDDDDDCDCDEEDDEEDCDDDDDDDDD
@7WQ
CAGGCTTGCAGCCAATTTACTGGAGCAGGGATGACGTAGCCCAGTGGCTCAAGTGGGCTGAAAATGAGTTTTCTTTAAGGCCAATTGACAGCAACACGTTT
+
CC@FFFFFGHHHHIJJJJJJJJJJJIJIGJJJJJJJIJJJJJIJGIGGGIGGI@FEIEGHIHHHHHFFCFFFFECEEEDEDDDDCDCDCDDBDDDDDDABD
@7WR
TATGTGCAAACAGGAGGGAGACTGGAGCCACCAAGAAATTGTCCTGATGATCTGTGGAATTTAATGACCCAGTGCTGGGCTCAAGAACCCGACCAAAGACC
+
@<?B=ABDFF?ADEIEBEIA<A9?BF>;FGFIIIIFFEDDF?FFFEIIC8<=CFGCDAC@CDCCE@;==?=?B>;36;;=3;;>AB?9@833955<8?B?B
@7WS
TCCATGCCTGTCACTTCCTCCAGCTTCTTTGGAGCCGCATCACAATACTGGACCTCCCCCACGGGGGGAATCTACCCCAACCCCAACGTCCCCCGCCATCC
+
@@@DDDFFBAFHHGGBBGGIJIIJFIJIGJJG>GDGIGGAHGIGECHGGIJIIJIGJIJG<AHFFCDD>>ACDCCDBDDDDDDB@B@<?BBDDDBDB9<AB
@7WT
GCTCTATGAACTCCTTCAGCATATTCTGAAGCAGAGGAAACCTCGGATTCTTTTTTCACCATTCTTCCACCCTGGAAACTCTATACACACACAGCCGGAGG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHJJJJJJJJJJJJJJJJJJJJJHHHHFFFFEEEEEEDDEDEDDDDDDDDDDDDDD
@7WU
GATGTATGGAGCTTCGGGGTGATCCTCTGGGAGATCTTCACCTATGGAAAGCAGCCATGGTTCCAACTCTCAAACACGGAGGTCATTGAGTGCATTACCC
+
B@BFDFFFHHHGHJJJJJJFHIJIJJJIGJIIJDHIJJIGIJJIJIJIIJHGIJIIJJIHEHHHHFFFFFFEEEEEDBBBDD<CDCDDAD:>CDDDCCCD
@7WV
GCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGC
+
?;?D:DD4B,2?3C;E:AAFFEEFI4C9C9A:?;:CDBD?@B?BDDADICEI3.8B;CEC7=@AC@=CCDACAADDDD6;>>A3>>>;>??(:AA9==;=
@7WW
CACCAGTGGAGGCCGGATGGACCCACCCAAGAACTGCCCTGGGCCTGTATACCGGATAATGACTCAGTGCTGGCAACATCAGCCTGAAGACAGGCCCAACT
+
@7;DDDDBHGADHGGGEHIIGHE7D8DFHIIGGIGBDHHHIFGIIIGCEGEHGHFD<A>AE@ECCCCCCCC@CBCCBBCCCCCCCBCCCCCCCCC@BBBBC
@7WX
CTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTT
+
CCCFFFFFHHHHHJJJJJJJJJJJJIJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJHHHHHHFFFFFFDDDDDDDDDDDDDDDCDDDDEDDD>>9@
@7WY
GTTTAGCATTCTTGGGGAATGGAGATGTTCTTACTGGAGACTCAGGTGGAGTCATGCTTATATGGAGCAAAACTACTGTAGAGCCCACACCTGGGAAAGG
+
@?@D=DDDHDAFHBHIGBGGIDHIIGHHGGHIIIGI>FGHIIIIA@?DGHI?@FCGEHGHGFHIIEEHHGIHHEHCHEDCDEECCCB=?B?CCBBBCBBB
@7WZ
CCACCAGCAGAAGGTGAACTTTGTCCCTCCCCATCCATCCTCCATGCCTGTCACTTCCTCCAGCTTCTTTGGAGCCGCATCACAATACTGGACCTCCCCC
+
?8?D=?DADADDDE2AEE9<DE>FEEIIIB@EEDIDICCCDEB>DEAADDDDCEI>CECBEIECDECEEC>AD;CD?8<??A>AAAAABD>A=?=>?<>?
@7X0
CCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGC
+
=<@BB:=:CBBDFIEF<F9BFIIH<CDGEGFF?@BGCEF@DF>FF>0??DFBDF<8FFFFEEFFFFFA?AB@BB@@?>?15=?ABAB(:<AB::44<?<??
@7X1
AAAACATGAAGCAGAAGTTACAAATTACAAGATAAAACTTGAAATGTTAGAAAAAGAAAAGAATGCTGTGTTAGACAGAATGGCTGAATCACAAGAAGCTG
+
CCCFFFFFFHHHHJJIIFHIJJJJJJJJJJJJJIIIJJJJJJJJIJJJJJJJJJIIJJJJJIJIIJJJGIJIIJJFHHGHFFFFFDEEDEEDDDBDDDDDD
@7X2
TATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTT
+
CCCFFFFFHHHHHJJJHIJJJJJJJJJJJJIJJJJGIJJJIJJJJIIJJJJJJIJIIFJJIJIHHFFDEEEEEDDDDDDDDDDCDDDDDDDDDDDDDDAC
@7X3
GGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGC
+
@C@FFFFFHHHHHJJIGHJFFHCGHIHHGHGIJJIJJJIJJJJJJJIHHHHFFFFFFFEEEEDEDDDDDDDDDDDCDDBDDDDDDDDDDDDDEDDDDDDDD
@7X4
CAAGAACAGATTGTGCAAAAGAACCAAGAAATAAAAAACATGAAATTAGAGCTGACTAATTCTAAGCAAAAAGAAAGACAGTCTTCTGAAGAAATAAAAC
+
CCCFFFFFGGHHHFHIJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJIHJJJIJJJJJJJJJJJJJIJHHHHFFFFEEEEEDCDEDDDEDDDDDCCDDDD
@7X5
GTCCCATCAGTTTGAACAGTTGTCTGGATCCATTTTGTGGATGGCACCAGAAGTCATCAGAATGCAAGATAAAAATCCATACAGCTTTCAGTCAG
+
B@BFFFFFHHFHHJIJIJJJJJHIIJIIGGJIJJJJJFHIGGIJJJJJJJIJJGGCHGIIIHJHIIGGIIJIJJGIHHHHHFFFFFFEEDEECDC
@7X6
TGAGAGACCACTCTTTCCCCAAATTCTCGCCTCTATTGAGCTGCTGGCCCGCTCATTGCCAAAAATTCACCGCAGTGCATCAGAACCCTCCTTGAATCGGG
+
CCCFFFFFHGGHHJJJBHGGIJIIJIIICHIDHIDHIEEGGIJJJJJIJJJIBEEGIHGFHHHFFFFACCEDDDDBCCDDCCCDDDD@BBBDDCCDDCBDD
@7X7
CTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCCACAGGACCACCCCAGTAGCATGGGCGTT
+
=<;=;@AACC><722?CB<3+3@7<2<?+7=*?B<ABAAA>B**:AA=0>3*>:666:';>;).77>>?>@>)..;;<;5;;===:;=533(83+8((0)0
@7X8
CAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGAC
+
CCCFFFFFGHGHGEIJJIJHHJJJIJJJJJJJJJJJJJJJJJJJIJJJJJJHHHGHHFFFFDDDDDDDDDDEDDDDDDDDDDDDDDDDDDDDDDCDDDD
@7X9
CTCATCCCAGCAGAACAGAAGGCTGTATGTTTGAAAAGGGCCCCAGGCAGTTTTATGATGACACCTGTGTTGTCCCAGAAAAATTCGATGGAGACATCAA
+
@@@DDD?BAFF<FB;FGHGEFBGAHCH@FCEG9FHBF9@GBBDF=F?/=F8BCDA@GAA;C=CHC>A>CACDDDB@CCCCC;AA>ABABA=:9C<AA>AC
@7XA
GGCAAAGCCAAGCTTGCCCAGTTTCGACAAAGAAAAGCTCAGTCGGATGGGCAGAGTCCTTCCAAGAAGCAGAAAAAAAAAGAGAAAAACGTCAAGCAGT
+
@@CDDFEFHGFBFGGGIJGEGIIIIGGGFHGFGIJIIJIJGGJJIGIGGGGGGHIIAHEHHGFFFDEECCEECDDDDDDDDBB??CCDBDB?BBDDDDDC
@7XB
CAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJHIJJJJJJJHJJJJJJJIJJJJJIJJJJJJJJJJJHHHHFFFFEEEEEEEDDDDDDDDDDDDDDDDDDDDDDDD
@7XC
GACACAGTGCCTCTTTCTCACTTTGATGAGAGCATGGCCTACATGCCGGAAGGGGGCTGCTGCAACCCCCACCCCTACAACGAAGGCTACGTGTATTAAC
+
@@CFFFDFFHHBDHIJJIJGCDHHHI,:CFGGGICHGIEGIGIGEHIIIFGIIGGHHFFFEDCECADDDD?BDDDBDBCDDBDDDD@>@CD(93<CDDE>
@7XD
AGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACA
+
@@@DFFFFHHHHHJIBGIJJIJIGJJJJJICIIJDHEGIIIJJGFHIHFGIIGHHIIIIIEGHIHIIGDHHHHFFFD@BEDDDBDDDD?AACCDDDCDDD
@7XE
ATTTATATGAGGCAAGAAGGCTTCCTGGCTCATCCCAGCAGAACAGAAGGCTGTATGTTTGAAAAGGGCCCCAGGCAGTTTTATGATGACACCTGTGTTGT
+
@C@DFFFFFDHHHIIIGGBHGIIEFHIGGGGCHIGIHGGGHIIIIIIIIIIIFCGAGDHG>GIGC>@=;EEDFFBCDBCCED@CCCD;A@CCDDDCD>983
@7XF
GAGGTGGCCCGACGTTGGGGCATTCAGAAAAACAGGCCAGCTATGAACTATGATAAACTTAGCCGTTCACTCCGCTATTACTATGAGAAAGGAATTATGC
+
@@@FFDDFHFFHHJJJIGGIJIIIHIIIIIGIJJIGGIGGGGIGIIIJGHGHHHHFDBDFFFDEDDDDCDDDDDBDBBDDCDEDDDDDDCDDBDDDCDDC
@7XG
GCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGAC
+
::;;BDD?C;BDFEGDEEF78:FCFF;EGIE>FC>DFF?<BBDF=FF3CFF==DDCE@@@=@EEACEEF@B@@BDCAC@>>B?BBBBB?B:>@>ABDDBB@
@7XH
CTCTGAAGATCATGTGGCCTCAGTGAAAAAATCAGTCTCAAGTAAAGGCCAACCAAGCCCTCGAGCAGTTATTCCCATGTCCTGTATAACCAATGGAAGTG
+
CCCFFFFFHHHDHJHIJGGHJJGHIIIIIJIJIGGDHGIJJJJIIIIDHIIJJJIJIIJJJIJBEBEF?BDDEEDEEDC@CDDDCCEFECDDDCDD@CC@C
@7XI
CAGCCATTCAAGAGCTGATGAGTAAAGAATCTCCTGTCTCTGCTGGAAATGATGCCTATGTTGACCTTGATCGTCAGCTGAAGAAAACTACAGAGGAACT
+
CCCFFFFFHHHHHJJJJIIJJJIJJJJJJJJJJJJJIJJJJJJJJJJJJJIIJJJJJJJIIJFIJJJJJJJJJJJJJHHHHHGFFFFFEEEECCDDBDDD
@7XJ
CAAAGCTTTCCCCCTCCCCTGATGATTAAACAGGAACCCAGAGATTTTGCATATGACTCAGAAGTGCCTAGCTGCCACTCCATTTATATGAGGCAAGAAGG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJGIJJJJJJJGHJIJJJDHIIHHHHHHFFFFFEEEEEEEFEEEEDDDDDDDDDD
@7XK
CCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAAC
+
@CCFFFDAHHHHHIIJJIIIJJJJIIGJGIGIJJJJJIIIIJIJIGIIIEGGICHHHHFFFFEEEDECCDCDEDDDDDDDCDCDCCDDDDDDDD9<ACDDD
@7XL
ATCAGTCTCAAGTAAAGGCCAACCAAGCCCTCGAGCAGTTATTCCCATGTCCTGTATAACCAATGGAAGTGGTGCAAACAGAAAACCAAGTCATACCAGTG
+
CCCFFFFFHHHHHHIJIIJJJJJJJJJJJJJIIIJJJIIJGIJJJJGIJHIJJJHIJIIJJJJJJJHHG?EFEDFFFFEEEEDDDDDDDDDDEEFDDDDDD
@7XM
CAGAACTCATGGAAAAACTTGAGGTAACCAAGCGAGAGAAATTAGAGCTGTCACAGAGACTGTCTGATCTTTCTGAACAATTGAAACAGAAACATGGTG
+
CCCFFFFFHHHHGJJJJJJJJIIJGHIJJJIJJJJJHIIIJJJJJJJJJJJJJJJJJJJIJJIJJJJHHHHHHHFFFFFFEEDEEEDDDDDDDDCDD:@
@7XN
TAAACTTAGCCGTTCACTCCGCTATTACTATGAGAAAGGAATTATGCAAAAGGTGGCTGGAGAGAGATATGTCTACAAGTTTGTGTGTGATCCAGAAGCCC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJFHIJJJJJJIJHHHFFFFFFFFEEEDCEEDACCDBDDEEDDDDDDDDD
@7XO
GGGAAGGACCCACATACCAACGGCGAGGATCACTTCAGCTCTGGCAGTTTTTGGTAGCTCTTCTGGATGACCCTTCAAATTCTCATTTTATTGCCTGGACT
+
??8+42BDA=DDDDA?CE9EFE:<?@@?@CCCBCDII@@@C=CEIDA?=;@??@6;;AAAAAAAA:(,:>>>9?:=AAAAAA<4>:::>>AA:3:3:8(2:
@7XP
GTCCAGGGGTATGGCACTGGGGCTTATGATACAACCACTGCTACAGTCACCACCACCCAGAACTCCTATGCAGCTCAGTCTGCATATGGCACTCATTCTGC
+
+===++2))0)+++++<+3<+)<:)@**:AB**0*):)**0=A=A3*9.)8==1=25/16())7)))7).>>5;;35((((-5=9,((((993((((+(((
@7XQ
TCTCCTGTCACTGCTGGAAATGATGCCTATGTTGACCTTGATCGTCAGCTGAAGAAAACTACAGAGGAACTAAATGAAGCTTTGTCAGCAAAGGAAGAAAT
+
=7+<==+<A,<AABBAAAA>=A7,<@<==4722+?A@@@AA71:?):=3***9=?B3/8>>9))))(=A=.=A>)77.7;)7>>;;6;>;>====?==?(;
@7XR
CAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGG
+
CCCFFFFFGGHHHJJJJIIJJJJJJJJIGIJJGIIJJJIJJJJJJJJIJJJJIIJJJIJIGIHFGHFFFFF@CEDDDCEDDDDDDDDDDCDCDBBBDDCBB
@7XS
GTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTAC
+
<@<?BDADDF?BFD;ACFAFHCCFEBFHIGHDDH??DHEHD@FGIIEDDBB8B;8B<8C@@;(5@=EEH9=?BEB;AA?ABA@>>;>;A:55,59:><CC>
@7XT
GAAGAAAGTAAGCAAGAACAGTTGATTTTGGATCACTTACCATCTGTAACAAAGGAATCATCACTTAGAGCAACTCAACCAAGTGAAAATGATAAACTTC
+
@@BFFFFFHHGHHJJJJJJJJIIJIJJJJJJJJJJIJJJJJJJJJJJJIHIJJIIJJJIJJJJJJJJIIIIJIJJHHHHHFFFFFEEEEDEDDDDDDDDD
@7XU
CATCCCCTTCCCACCACAAGGCTTTAAGCAGGAGTACCACGACCCAGTGTATGAACACAACACCATGGTTGGCAGTGCGGCCAGCCAAAGCTTTCCCCCTC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJHHIJJJJJJJIJJHIHIIJIJJJJJHHHHFFFFEEEDDDDDCCDDDDDDDDDDDDDDDDDDDDDDDD
@7XV
GGCCATGTTGCAGCTGACCACCCACCTGCAGTGTACCGCCGGAAGCACCAGGAGCTGCAAGCCATGCAGATGGAGCTGCAGAGCCCTGAGTACAAGCTG
+
@@@=BDDDD<4?BB<AFFIIIE@8C:<*?EB?D*9CGEADA;FA;@@@@AC;C?D27@AA(;?5;>AA5@5(55(9<>?A9>8><@<@3<4+4:AB?AA
@7XW
GGGTGAGGGAGCCTTTGGAAAGGTCTTCCTGGCCGAGTGCTACAACCTCAGCCCGACCAAGGACAAGATGCTTGTGGCTGTGAAGGCCCTGAAGGATCCC
+
=?;4AB3B?8CF?FGGGHHIEGIE4EGB?E49DDEHGHIGIIHIGFE@F=@D;;AEE<D;@ACCCB?C:;3>ACBA?@B8<?CD(9<82?BC>>9?@3<3
@7XX
AATTTATTAAGGGAAGAAGAATTTGGTGTTGATGATTCTTATTCTGAACAAGGAGCACAAGACAGTCCGACTCATCTAGAGATGATGGAAAGTGAGTTGGC
+
CCCFFFFFHHHHHJJJIJIGIJJJJJBHGHIJIJJJJIJJJJJJJJJJJJJJJGJJJJJJIJJJJFHJJJHHFFFFFEEEEDCEDDDDDDDDACCDDEDDD
@7XY
GGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAAT
+
CCCFFFFFHHHFHIIGHIIJFHHJJIJJIJJJJJJJJJJJJJIJIJJIJJJJJJIJIJJIJJJJJHGHFFFFFCEEEEDDDDDDDDDDDDDDDDDACDDE
@7XZ
CAGTCACGGGAGCCCTCCCTGAAGAATTCCAACCCCGACGAGATTGAAATCGACTTTGAGACCCTGAAGCCGTCCACACTGCGTGAGCTGGAGCGCTATGT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJIJJJJIJJJJIJGHHHHHFFFFDDEEDDDDDDDDDDDDDDDDDDDDDDDDDBDDDDDDDDDDDDDDDDD
@7Y0
CATCAACCAAGAAGGAGAATATATTAAAATGTTTATGCGCGGTCGGCCAATTACCATGTTCATTCCTTCCGATGTTGACAACTATGATGACATCAGAACGG
+
?;@DD?DD=D?<D?9<BGCBHCFHCHIEFAG:?BFG991???(?;A/55@EC;AECHC@CDEC7@6>C@C88=;9>5::@@<>CCCA>@@44>AC>:CC.<
@7Y1
CAGAAATCTCCAGGACCTCAGCGAGAAAGGAAGTCATCTTCATCCTCAGAAGACAGGAATCGAATGAAAACACTTGGTAGACGGGACTCGAG
+
@@@DFEFFFHHHHJJJJIGGJIIGHJJJJJGGJEHIIIJJJJJJJJJIIIGGJCFHJGIJGJJJIHGHHHHFFFFFE;@CCCDDDDDBDDBB
@7Y2
CAGGGCTTCTCTGTGGAACTGGAAAGTGAAATTTCAACCACAGCAGATGACTGCAGTTCAGAGGTAAATGGTTGCAGTTTTGTGATGAGAACAGGAAAGCC
+
@CCFFDEDFGHHHIJIJJGGGGEHGJ@CHIJJJJJJIGGEHIFGIIHIIIJIJIEHDHGIEGHI=FHCGHB7CHEEFEFFFDDDCEDEEEDDCDDDDDDDB
@7Y3
CTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATG
+
@@@DD;DDDHHFFIF@HGGBGEDB@FG;?FDGI<?DGEGIEEHAEHBGIIFEHHEEEDECBCCCCCACCCCBB?BB=?AB?B@C>ACB@CB@BBBCCCC@A
@7Y4
GACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCAAACAGCCAGCCTGTCCAGGGGTATGGCACTGGTG
+
??=14A<<D:<A?E<<<E3<222++ACEE?9D??0B:?BDDDEII4*?DEIAE@B====5-='(,;.((5>(,<?9???<5>44:30&5>A((+94((8>9
@7Y5
CGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCT
+
?;+AD:BDB?CCFDB@;;CFFCCAFHHEHFDEFIIIIIFCFE>FGFB@GEF@F6(.=@F@FEEFFIFCAEEF@D?DCCBB=;;;>AABB:>3>>@BBB@?>
@7Y6
CAAGATGAAGGGCTTCTCGTCCTCAGAGTCGGAGAGCTCCAGTGAGTCCAGCTCCTCTGACAGCGAAGACTCCGAAACAGCATCTGCATTGCCGGGACCGG
+
@?@DA?+AFFB6?EBB:ACFHIGHGCGD:C@FGGB;8DD??D?D8)/==B3CCHEGGIEG:>?ABBAAC5@ACBBB;=:<??CCCAACCA@CC9<9<>@@B
@7Y7
AACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJIEHIJJJJJJJJJJJJJJJJJHIJJJJJJIIJIJJJJJHHHHHFFFFEEEEEEEDDDDDDDDDDDDDDDDDDD
@7Y8
GTAACTCCTTTCCTCCTTTGCCGACGATGCCAAGGGAAGGACGTCCTATGTACCAACGCCAGATGTCTGAGCCAAACATCCCCTTCCCACCACAAGGCTTT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIIJJJJJIIJIHHHHFDDDBDDDCEDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDD
@7Y9
CTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCC
+
CCCFFFFFHHHHHJJJJJIJJJJJJJIJJJJJJJJJJJJJJJJJJJHIJJJJJJIGHIIIJHHHHHFFFFFEEEEEDDDDDDDDDDDDDDDDEEDDDDDDD
@7YA
CTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGT
+
CCCFFFFFHHHHHJJJJJJJJJJIJJJJJJJJJJHJJJJJJJJJIJJJJJJJJJJIJIJJJIIJJJJHGGHHHFFFFDEDDDDBDDDDDDDDDCDDDDDDC
@7YB
CAACAGGCAAAACGGGAGGAGGAGCGCAGCCCAGCTGCCCCACCACCTCTGCCTACCACCTCCTCTGGCAAGGCTGCAAAGAAACCCACAGCTGCAGAGGT
+
CCCFFFFFHHHHHIJJJJJJJIJIIJJJJIJJJJJJJJJJJJJHHHHFFFFFEEEEEDDDDDDDDDDCDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDC
@7YC
GGAGAGGAAAGGAAAGTGAAAAAAACCTGAGAACTTCCTGATCTCTCTCGCTGTGAGACATGTCTGAGACTCCTGCTCAGTGTAGCATTAAGCAGGAACG
+
B@@FDDFFHHHHHJJJGHGIJJJJJJJJJJJJJJJJJJJIIJJJJJJIJJJIJGIIJHHHHGHFFFFFFEEEEECDDDDDCCADDDDEDDDDCDDDDDDD
@7YD
GGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTAC
+
CCCFFFFFHHHHHJJJJHIJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJIIJJJJHFFHHFFFFDD=@CDDDDDDDDACDDDDDDDEEDDDDDDDDDDDDD
@7YE
TTAAGAGGAGAGACTACTTGGACCTTGCGGCGTCCACTCCATCTGACTCCCTGATTTATGACGACGGCCTCTCAGAGGAGGAGACACCGCTGGTGGACTGT
+
@@CBDFFFFHFHDEGGIJJJIHIIJGJJJJIHIHIJJJJJIJIJIFGGFGHHHFFFFDFEECCCDBBDDDDDDCCACDDDD?BDDCDDB@BDD<ABBDCB>
@7YF
CGACGAGATTGAAATCGACTTTGAGACCCTGAAGCCGTCCACACTGCGTGAGCTGGAGCGCTATGTCACCTCCTGTTTGCGGAAGAAAAGGAAACCTCA
+
@@@DDFFDFFHHGEHJJJJGGHGEHJIJJFJIJIIJJJIJJJGGGHIIAEGHHGHHFFFDDDBDDDDEDDDDDDCDDCD@@BB@BDDCCDDDDDDDDDD
@7YG
AAACAGAATTGTTAGAAAAACAGATGAAGGAAAAAGAGAATGATCTTCAAGAAAAATTTGCACAACTTGAAGCAGAGAATAGCATTCTTAAAGATGAAA
+
@@@FFFFFHDFDDHGIJJJJAHGIDEGIGFIJJJJGGGGIADHGEIIEIGHCDHII9BDGGGHIJIIIGJJHHGGEFFFFFE@EEDACDCDCCA>CCDD
@7YH
GGGAAAGTGGCATGGTGATGTGGCAGTGAAAATGTTGAATGTGACAGCACCTACACCTCAGCAGTTACAAGCCTTCAAAAATGAAGTAGGAGTACTCAGG
+
@CCFFFFDHHHHHJJCFGGHFHHIGIAEHIIJIGEHGGIIE?DFGIIGEIIJJFIIIIIFICGIGGG>EHEGHEHEHHFFFDC@CA;@>C>A5>@CCCCC
@7YI
CAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGAC
+
@@@DDDDD>:DFFII@BA<ACFH@GDE????<9?CD<D??:00??:?GIG@HGGHBHFCDC@GHIG>C@?EAHE85;?<398=C>:@:@CCA>C@::@CC
@7YJ
CACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJIJJJHHHHHHFFFFFDEEEDDDDDDDDDDDDDDDDDDDD
@7YK
CAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAAC
+
@<?BDDDDHHD8AF@:A;CACFHIIIGBDFFHBFDDH?:?@BDGGA<BCAGG@F=@F7CGID@AC6.7=@D>;;@@>C;;>CCBB?5<>(>@<?55:>CC>
@7YL
GGAAGAGTATAGCTAAAACCACAAAAGTGAAGGAGAAGTGGAAGCGAACACAACGCGCAACGCCAAGGCCCCGGCACCTAAAAGGAGGAGGAGAAATA
+
7(8(((2)))))).))29)=(28(.2)))))2)((((2.::))0.((('').-(''''',''3'''(((+(&&&))&+(++(((+((&+(&((++((+
@7YM
GGCTGTTGGTGTCAGCCAGGAGGGTCCTCCAGGCCTTCCGCCTCAGCCTCCACCACCAGTTGCTCAACTGGTCCCCATTGGGCCCCTGGAAAAAGCTTGGC
+
1?;DD:AD8ADFF@FBEG;::<FBFGE>9?DFEFF9D9BFF=@-=B<7FA@CDEF?;EF=?B7?D@A>3>>;55;;;?A:(,9288?<8?AA9?@(4>>?B
@7YN
CTTTTCTCCATGGCCTTTCCAGATAATCAGCGTCCACTGCTGAAGACAGACATGGAACGTCACATCAACGAGGAGGACACAGTGCCTCTTTCTCACTTTG
+
CCCFFFFFHHHHHIJJJJJJJJGJJJJIIHIIJJJJIJJJIIIJGIIJGIIJIJJIJJJGIGHIJJJJHHHFFDDDBDCDDDCCDDDDCCDDDDEDDDDD
@7YO
CAGGGCAGAAAATGTACAGTCATGTGATACTCAAGTAAGCTCTTTATTAGATGGAGTTGTGACTATGACAAGCAGGGGTGCTGAAGGATCAGTTTCTAA
+
CCCFFFFFHHHHHJFHIJJIJJJJIJIJJJJJJJJGHIJJIJJJJJJJHHEGHJGIGGIFGHIJJIJJJJJJIIHIHH9BCEECEDDBDDDDEEEEDED
@7YP
GTCCATTTTATTGCTAAAATACAAAAGTTCACGTATGAAGTTCTTGCATTCGTTTTTTTTTGGAGCAGGCATATGGGCAACAAAGCTATGGAACCTATGG
+
@@CFFADFHBFHHGIGIGIIGGFGHEHFHBFHGIGGIIJIFFHICDHIIIHIHGIIIJIJFDFCCCDCB@BCDDEDDDCDDBDBCCCCCCDDCDDDDDCC
@7YQ
CCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGG
+
CCCFFFFFHHHHHJJJJJJJIJJHIJJJJJJJJIJJJJJJJJJJJJGIIJJJJJFGIIJJJJHHHHHHFFFFEDCEEEDEDDDCDDDDDDDDCDDDDDDDD
@7YR
CTCTCACCAAGGGAGCATCCCCTCAGTCCTCACCATGCCTCAGGAGGTCAGGGCAGCCAGAGAGCATCCCACCTGCTCCCTGCTGGAGCAAAAGGCCCC
+
@@@?DDDDFFHHDDHGB?F<AFGGIGGHBFGDCDDD>DHIICGFFEGDCEFHHGCG=CEHCAADED>@C;ACB?5;>@>??CBCCC?B?@CCCA@@8@B
@7YS
CAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCC
+
@C@DDFFFAHHHHJGJJGJJJHIIJJ>FHHIJIJJBGGIIIJIIFIIGIIIJJJGIHIIHIEHFFFFFFEECAECCCDDDBDDDDBCDC?>:<CDDDDCB
@7YT
CGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCG
+
@@@DD?DDDCFDF?FBDHIICFD??DD3BGGGBADFDGGIHIGHIHH8BEDDCCBACCCCA@AACCCABCCCCC>9B<<BBB?<BBBC@C>ACDCCCCCC9
@7YU
CTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTT
+
@@CFDDDFFHHHHJIIIIIJJJJEGHCIIEIJJJIDIIJJIJJJJIJJJJIHJJGJJJIJJHFHHHHFFFFFFDCBDDDDDDDDDDDDDDDCCCCDDCBDD
@7YV
TGCCAGTTGCTTTAATGGAAACGAAGAACCGAGAAGGGTTAAACTATATGGTACTTGCTACAGAATGTGGCCAAGGTGAAGAAAAGTCTGAGGGTCCTCT
+
@@@DDADEDHDBHIHJJEGHIFG@F=GHI?GGG@FFHB9?FHGCHG==BGH8CFHGGI>E@EDCCHH3=A??BDDD.;ACA@CCCACC@@CDDB5>ACDC
@7YW
CTCTATACACACACAGCCGGAGGTCATACTGCATCAGAACCATGAAGAAGATAACTGTGTCCAGAGGACCCCCAGGCCATCCGTGGATAATGTGCACCAT
+
@?@DB;DDDFFFFF?FFG182111?*?FDE>AEGEFEIFFIEEC==8=FCFAFFE;;C==CC>>E??B?@CCBBB?BB@:>?88?@8:@A::++>>:??@
@7YX
ATGCTTACAAATTTGACTTCCACGGCATTGCCCAGGCTCTGCAGCCACATCCGACCGAGTCGTCCATGTACAAGTACCCTTCTGACATCTCCTACATGCCT
+
@?;ADEDEHFAHDB?GEBCF@H@G@8E8>G<FEHG==FHDBACEGD8BGC=8@18;EEE5>AC??B>@5>@CCC>>;>@CC9>C>ACC>ACCACCCCC@AC
@7YY
TTTAGAAATTGAACATCGAATAAATATTGAAAAACTTAAAGATAATTTAGGCATTCACTATAAACAGCAGATAGATGGTTT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJIJIJJJJJIJJIJIIHHH
@7YZ
AACAGATTGTGCAAAAGAACCAAGAAATAAAAAACATGAAATTAGAGCTGACTAATTCTAAGCAAAAAGAAAGACAGTCTTCTGAAGAAATAAAACAGTT
+
CCCFFFFFHHHGHJJJJJJIJJJJGIJJJJJJJJJJJIJJIGIJIJJJJJGIGIIIIJJJJJJJJJJJHHHFFFFFEEEEEEEDEDDDDCDDDDDDDDAC
@7Z0
AACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCC
+
CCCFFFFFHGHHHIJIJHIIIIIJJJJJJFGEGIJIGIFGIGJJJIFIIBFGEHIGHGIBHHIJJIHGGHHFFFDEEEACEEDDDDDDDDCDDCDDDDDDD
@7Z1
CAGATTTCGCCGCCAGCTTTCTGAACCCTGTAACTCCTTTCCTCCTTTGCCGACGATGCCAAGGGAAGGACGTCCTATGTACCAACGCCAGATGTCTGAGC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJHFFFDEEEDDDDDDDDDDDDDDDDDEEEDDDDDDDDDDDCEDEDDDD
@7Z2
CACTGCGTGAGCTGGAGCGCTATGTCACCTCCTGTTTGCGGAAGAAAAGGAAACCTCAAGCTGAGAAAGTTGATGTGATTGCCGGCTCCTCCAAGATGA
+
@@@DDFFD:DFHHIG@G9FHIGIIIIHIGEDHIGIBHADDGIBGEHCHHGGFECEHDC@DCCE3=>CCCCCCCCCDA@DDCCCBBB9@?AACC?C?CC@
@7Z3
GTCACCTATCACGACAAATCACCGGCCTTCTCCTGACCCCGAGCAGCGGCCCCTCCGGTCCCCCCTGGACAACATGATCCGCCGCCTCTCCC
+
<?@BB>DB?DDDCEEGFBFHII@G@ADDD?F4B??AGHGGA<@AAEHE=<AABBB?B/'87A878B@B81>?8<ACC@@A8880-9B>CCCC
@7Z4
TGATGTTCAAGATCGCCTGTCAGCTCTTGAGTCACGAGTTCAGCAACAAGAAGATGAAATCACTGTGCTAAAGGCGGCTTTGGCTGATGTTTTGAGGCGTC
+
CCCFFFFFHHGHHJIJJJJGIIHJJJJJJJJJJJJIHIHIJJJJJJJJJJJJJIJIJIJJJJIJJIJJJJJHHHHFDDDDDDDCDDBCCDDEDB?DDDDBD
@7Z5
CAATGATGAGCAGTTTGTACCAGACTATCAGGCTGAAAGTTTGGCTTTTCATGGCCTGCCACTGAAAATCAAGAAAGAACCCCACAGTCCATGTTCAGAA
+
CCCFFFFFGHHHHIJJJIJJJJJIJJJJJJIJJIJJJJIGHIIJIJJJJJIIIIJIJJJJIJJIIJJJJJJJJGHHHHHFFFDDDDDDDDDFDDEEEDDD
@7Z6
TGAAGCCGTCCACACTGCGTGAGCTGGAGCGCTATGTCACCTCCTGTTTGCGGAAGAAAAGGAAACCTCAAGCTGAGAAAGTTGATGTGATTGCCGGCTCC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJIJJJJJJIJJJJJJJJJJJJJJJHHFFFEEEEDDDDDDDDDDDDDDCDDDDDDDDDDDDDDEEDDDDDDDDD
@7Z7
AAAAGAAACTCTTTCATCTGCTGCTAAAAGTGGTACAGAAAAAAAGAAAGAAAAACCACAAGGACAGAGAGAAAAAAAAAAGAGGAATCTCATTCTAATG
+
@@@FFDDFHDBFHGIIIEHIFGIHCHHIGECCC:CGHGHIGIIGIIGIIIIIIIIHIIIIHAA=BEEFCAADEDDDDDDDD>8<A??AA(:ACCC>@CC>
@7Z8
CGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTAT
+
CCCFFDFFHHHHHJIIIIJJJIJIJIGHGHIIJIIJJIIIGGGGEHEGHJJIIIJEDEDFFFDCABBDBDDDCDDDCDDDDDDDDDDC@CDDECCCDDDDD
@7Z9
GGCCCTCCAACCCCCCCACACCATCCAGCACCCCAGTGTCCCCACTGCATCATGCATCTCCAAACTCAACTCATACACCGAAACCTGACCGGGCCTTCCC
+
;@8D??:A?AFFFFEGIEICGFB?BF?FABC(-55CEEI;=@=7:...77@;>(>;>A(5--5>B>:>B5(5>:5>>>AB@B>5<B@9?>5<@BB0@BA?
@7ZA
AGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGC
+
CCCFFFFDHHHHHJJJGHIIJJJJHJJIJJJJJJJJJJJJJIJJJJJIJJJJHIJJJJJJJJJJHHHHHFFFFFEEEDEEDDDBDDDDDDDCDDDFEDEDD
@7ZB
AGAAGACCTTGGTGATTTAAGGCGGCAGGTTAAACTCTTAGAAGAGAAGAATACCATGTATATGCAGAATACTGTCAGTCTAGAGGAAGAGTTAAGAAAGG
+
C@@FFFDDHHHHFEG@GHGGH@CCDGIIJJIJJJIJGHG=CFGIIIIIJJJGHEHHHH@BCDD@CFEDECEEDEDACCCCDCCCDBDBBBBCDDDDDCCDB
@7ZC
ATTTTCGTGTTGGACCATAATTTAAACACTCTTATTCTCGTGATTATTAAGGCAACCAAAACTATTAGTAATAGCAATTTGGCTCCTGAAAAACTAAACTT
+
;<58-.8>=(2(()))()...).).::=()).3>391)3(0(:)))))).0::(0.(7(66=3/;>?)).:)893)6).)))))(5((3(:((,(,3(5,(
@7ZD
TATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCC
+
@@@FADEFHHHGFHHGIIAEHIIIGGIGEHHGIEFHHECHID@FGIIGIGGGGIGGGGIGIIHEEEFFFFEFFDEEDDCEDDCCCDD?CCACDBDDBB<?A
@7ZE
AGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCC
+
CCCFFFFFHHHHHJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHHHHFFFFFEDEEDDDDDDDDDDDDDDDDDDDEDDDDDDDDDDDDDDD
@7ZF
TCGCCACAGCCCATGCATTTGTAATAATCTTCTTCATAGTAATAGGCATCATAATCGGAGGCTTTGGGAATTGACTAGTTGCCCTAATAATCGGGGCCACC
+
11=++<?AB;+++<?3=>7AAB>ABB+>?<*:=@B*:==77:*:****00=?<49*7A7<:=5>)7)'()(.=>@??>;>((..(,5;5;;(,;''5)(+(
@7ZG
CACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATG
+
@CCFFFFFHHHGHIGIIGIJHJIIIGHIJJJJIJIGIIJIHHGGIJJICHGIIJJIJJHHFFDDDDDDDDDDDDDBCCDDCEDDDDDDDDDDDDDDDCDCD
@7ZH
GCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGG
+
C@CFDFDDDDFHGIJHHGEFH;FFCHIIIEHIIGIIJJI.?BAHIJFGAGGEHHHHHFDEECCCEC@C@?CD;@ACCCC@CBCCACDDBC@?(:@CCDDB
@7ZI
TCGTGATGTGCCTACTAAAAATTGATCTGCCTTTCCTTCTGCTACAGCTCTGATTGTGCCATACTGATCAGGAACCTCTATTTCTCTTTCAGGATTC
+
CCCFFFFFHHHHHJJJJJJHHGIJIJJJJJJJJJJJJJJJJJJJJJJJIJJJGIJJHIJJJIIJJJJJIJJJJIJJJJJHHHHFGHFFFFFFECEEE
@7ZJ
CTTTGATGAAGACAAAACTTTTGTAGCAGAAACATTGGAAATGGGTGAGGTTGTTGAAAAGGATACAACAGAACCCATGGAAAAACTTGAGGTAACCAAGC
+
@@??DD>BBBBDFEBA:C<<:A+33ACF<3C9CGCDF<*::CDDBD:FFFG@FFD>@==4FE==CE=@@6?>>=(9?B@>B@A@=?A>B;@<,,555@<<?
@7ZK
CCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCT
+
@CCFDFFFGHHHHIJJJJJJJIIJIJJJJDFHIJGEIIII?DDHIGIJIIJJJJJJJJJJJJJJJHGHGHHFFFFDDDDDBDDDDDDCCDDEDDCDCCCDD
@7ZL
CTACAAGTTTGTGTGTGATCCAGAAGCCCTTTTCTCCATGGCCTTTCCAGATAATCAGCGTCCACTGCTGAAGACAGACATGGAACGTCACATCAACGAGG
+
CCCFFFFFHHHHHJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJIJJJJIJJJJJJJJJJHHHHHFFFFFEEEEEDDDDDDDDDDDDDDD
@7ZM
CAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTT
+
??=;DD)@D??DA?CFI??@BB<FC<BFHGCH@FD;D<BBFGG9?BDF8BHE=GGEHA@GHGGEEHHCH@DDEEC@A6>@C>C@35??C<CC(599AA:>
@7ZN
GAGGGCTCCAGCTTGTATCACCATCTCCATATCATTGAGACCAAATTTGAGATGATCAAACTTATAGATATTGCACGACAGACTGCACAGGGCATGGATT
+
@@CFFFFFFHHHHIIHHIGIIJJJIJIJJJJIIGIIGGFIIIJJIGIGIGGHGIIGHIIJIIGIIIIGHDHGJJJJHHHEBEEECCDDCCBDBDCDDDCC
@7ZO
CTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGC
+
<@??BDDD?BA>FCE>+AAEFDCHGEGEFGH<DFGIDGD;@BBADAF>ADF;BBG<=@)=C=9=;=;6=?);;@BCC:;>CCC@3;=@?<CCCCBC9ACC
@7ZP
CACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGG
+
CCCFFFFFHHHHHJJJJJIJJIJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJIIJJJJJJJJIJJJHHHH2?BFFEDEEDDDDDDDDDDDDDDDDDDDD
@7ZQ
GCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGC
+
@@@DFFFFHA?FDHGIIIEIIIICHIHGIIGBFFHIIIIIGFGGIIGDEEGGGIHGED;=@EHGAHEFGGCEF>B;=AECCCC?CBCCDCDDDDCACC?B
@7ZR
AGATGATAGCCGTAATAAATTGTCGAAAATACCTTCAACACCCAAATTAATACCAAAAGTTACCAAAACTGCAGACAAGCATAAAGATGTCATCATCAACC
+
@C@FFFFFHHHHHJJJJJJJJIHJIIJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJHIJJJJJHHHHHFFFFFEEEDDDDDDDDDDDDEFDDDDDDDD
@7ZS
CAAAAAGAAAGACAGTCTTCTGAAGAAATAAAACAGTTAATGGGGACAGTCGAAGAACTTCAGAAGAGAAATCATAAAGACAGCCAGTTCGAAACTGATAT
+
CCCFFFFFHHHHHJJJJJIJJJDHIIIIJIJJJJJJFHJJIGIIIGGHIFGHGIGGHGHIJJFIIIFFBHFHFFFFFFECECEDDBDACCDDDDDDDDCDA
@7ZT
GATACTTGTGCCCAGCAATCAGGTGGTCGTACAAACTGCATCAGGAGATATGCAAACATATCAGATCCGAACTACACCTTCAGCTACTTCTCTGCCACAA
+
CCCFFFFFHHHHHJJJJJJJJJJCGHFIJIIIJJJJJJIJJJJIIIJJIJIIJJJJJJJJJJJJIJIIJHHFFFFDEEEECDDDDDDDDDDDDDDDDDDD
@7ZU
CTTCTCCCCAGCCCTCTTCACAACCTCTCCAAATACACAGACAAACTCCAGAAAGCAAGAATGCTACTCCCACCAAAAGCATAAAACGACCATCACCAGCT
+
?@@FFDEDDFFDDFFHCGGIGIGIEHG@EHGIIIIGBA@B@GGHIEEIIIIIHIGIIIA@FGIBGIIHHHHHFFFDDDDECCCDDDDDD:B@ACCDDC?<C
@7ZV
ATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJIJIJIJJJJJJJJJJJJJJJJJJJJJJJJJIJJJHFFDDDDDDDDDDDDDDDDDDDDDDDDDDDDCEDDDD
@7ZW
AAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCAC
+
@CCFFDADFFHHHJJIIGIIHIIIHIJJIGIHIJJIIIIIJJJJIGGHJIJJHHFFFCB?>AEEECEDD@BDDDBDDDDDDDDDDDDDDDDDEDDDDDDDD
@7ZX
TGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTAC
+
@?<BDFFDFDHHHIIIGIG>CCEFHGGHEG?DF?GIDGE?FFGIGIICBGGDEGIGIIGGHCECCDECEDCEAED@CDDDDDDDDDDB<BDCDCCCCCCD
@7ZY
CCGAAACAGCATCTGCATTGCCGGGACCGGATATGAGCATGAAACCTAGTGCCGCCCTGTCTCCATCCCCTGCACTTCCCTTTCTCCCACCAACTTCTGAC
+
CCCFFFD?FHHDHIGG@FHIGD<E<DCFIIIIIIGIIB=@CGHGHEHH@HGEEHBB?AB>;@CCCC@BBBCB?CCCCCCCCCC@>>CCCBBAA0>:>>CDC
@7ZZ
CCCCTTCCCACCACAAGGCTTTAAGCAGGAGTACCACGACCCAGTGTATGAACACAACACCATGGTTGGCAGTGCGGCCAGCCAAAGCTTTCCCCCTCCTC
+
C@@FFFFFHHHHGJJIIIHIIJIIEHIJIHIFGIIJJJJJIGEGGIFFEHIJJJIIIJIGHHHFFEFDDEEDCCCDDDDDDDDDDDDDDDDDDDDDDDDDD
@800
GTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCC
+
?==DAD?B=FDHHBG@GB<8E=B1CGGGGI4:?2@6?DH@E>8ABHADECA??EHEE@;>D@AACC?>AC?BB=BBBBB7(8<CA:>>@CC>C@CBBB@
@801
CACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACC
+
@C@FFDFFGFFDHGEGHIGGHGHHDHHHGGGIGHGGHIGEGEHGEBDHGGIHJEDHGGGGHGGIGECEFHEFFFCDD>BBBBDDDEDDDECD>B>BDB@A<
@802
AGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGC
+
@@@DDDDDHABDDH?<BEEBG?C;<:):BGHIIIIGGIB==25@@D@GIII@3?AE7?BBEBB@@CAC;@C;A@CBCB@(,5>CA?0(+)++:???2<9A
@803
AGAAACCCACAGCTGCAGAGGTCTCTGTTCGAGTCCCTAGAGGGCCGGCCGTGGAAGGGGGACACGTGAATATGGCATTCTCTCAGTCCAACCCTCCTTCG
+
@@@DDDFDGHFHGIBHGIHIGACEHGFFEF@BF?DHGGGHIIIIGIGGDEE:BD?AEDDDDDDBDB8?8@AC@CC?CCCCCDCDDD>AACAC>BD@BCCAB
@804
CTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGT
+
CCCFFFFFHHHGHJJJJJJJJJJJJHIJJJJJJJHIIIJJJJJJJJJJJIJIJJJJIJJJJJJJJGIHHHHHHFFFFDEDBDDDDDDDDDDDDDDDDDDDC
@805
CTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTT
+
@@@DDDDDH<F?CCAFFHHCEHCFHFGHGIIIGEHIAHBGDHEHEBGDAD>BHBEHEIIICE=C=CHEEDDEDA<:?B=BB?B?BBBB:ACC:CCBB3508
@806
GAAGGGACGGTCGGGCAAAAGCTAAATTGTGATGACGTTGGGGGGATGCGTGCAAGGAGTGGGGGGGGGGGGGGGGGGGGCGGGGGTGGGAAGCGAAGG
+
++1++)+2)))+))1?)1))*)0*******/0*/9*(((.644'&))+(&(&&(+(((+((((&)0&&0)5&&&)&)&&&&)))0-&)&0((((&+)))
@807
GTTGGCTGGGAAGCAGCATGAGATTGAAGAGCTAAACAGAGAGCTGGAAGAAATGAGGGTTACCTATGGGACTGAAGGACTGCAGCAGTTACAAGAATTTG
+
?;?A?3AD?FFFF?:AEGAHHG>EHEHECDHGHIICDBB;DFHHHID?DFGEBCFGIID(8=@GHAAE;=A;@??@:>;;>;;AC>59ACCCC@C<?ACCC
@808
ACCATCCAGCACGCCAGTGTCCCCACTGCATCATGCATCTCCAAACTCAACTCATACACCGAAACCTGACCGGGCCTTCCCAGCTCACCTCCCTCCATCGC
+
CCCFFFFFHHHHDHIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHFFFFFEDDDDDDDDDDDDDCDDDDDDDDDDDDDDDD
@809
AAACAGAGAAGCTGCTCGAGAGTGTCGCAGAAAGAAGAAAGAATATGTGAAATGCCTGGAAAACCGAG
+
CCCFFFFFHGHGHJJJIHEHEGCFFFHEIIHIIIHJIHIJJGGGIIJFHIJICHGIGIIJJJJGHGFF
@80A
CCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCAC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJIIJJJJIIJHHHHFFFFEEDCDDDDDBDDDDDDDDDDEDDDDDDDCDDDDDDD
@80B
CTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGG
+
::8=42=?B?CAAAB9EEGGHEEHGEFEICHCHIDGGGBBFHC;;BFBFBFCF<C=FH9CHDHEH>EACC>A)=7?3777AC;..>AC;ACC@C?CCC:3<
@80C
GCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATAC
+
CCCFFFFFGGHGFDIJJIGHIJJJJJCGHHEIGIJIGIGIGIIGGHIJGIGHIJIIGFHHFDEEDEEEEDEDDDDDDDDDBBBDDDDD@CC@CDCCCDCDD
@80D
TTAGAAGACAGTAAAAATAAACAGGAATTAGAGTATAAAAGTAAACTTAAAGCACTTAATGAAGAGCTTCATTTGCAAAGAATAAATCCAACTACAGTGA
+
@@@FDEF8FDFFFIIGIDHIGIDHGGGGGIEBE:?GHIIII<DFCEHGIIIIIIIEDHIDHHG>DGGGIIIEIIIFGIEGGH;CH@@CFFD@CE>CCCCC
@80E
CAGCAATGTGAGCAAGAAGGAGCCAGCGCCCATGAAGAGCAAGCCCCCTCCCACGTATGAGTCGGAGGAAGAGGACAAGTGCAAGCCTATGTCCTATGAGG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJIJGIJJHEFFFFFEFDDDDDDDBDDDDDDDDDDDDDDBDDDDDDDEDDDDDDD
@80F
GAAACTCTGAGAAACAGCACTCATAGTAGCACAGCTGCAGACTTACTACAAGCCAAACAACAGATCCTCACTCATCAACAGCAGCTTGAAGAACAAGACC
+
@@@DDDFDHDFDHGGH;FHIIGIIIIIGGIIIIIIGIIIIIIIIIIIIIIIIGGIHIHGHGIEGHGIIIIIEHFEHHFFFFFCACCECDDDDDDDCCDDD
@80G
CTGAGTATCAGGAAGGCAACCAGGGTCTGGGATCCCGGGACAATATTTGATTGGCTCGTTGAGAAACCCTACCACCTCGGGAAACAGAGTGCTGTGAGCTT
+
870@(29<8).).2.51((33((((2:3))1.=52)((-(((.))/)>)/.))():)'-().66999=8((((,:(8,,'&)&((((((+(5((+((+(+(
@80H
CAAGGAGAAGGCAGGGTGGATCCTGATCTGTCCAAGCCTAAAAACCTTGCTCCTTTACAAGAGAGTCAGGAGTCTTACACAACTGGGACTCCCAAAGCAAC
+
@@@D7BBDHBFFFHDA<CFG<FHHIIGHEGGHHGIEGHIIIIIIICGGHGDHGHICGGC@DACEHHHDEDEE;@CCD<CCCB@@:>B<?BCC?CC?CCCCB
@80I
GGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACAC
+
CC@FFFFFFHHHHJJJIHIJJJIJJJJJFHIJIIJJIIJJJJJJJJIJGIJJJJJIIJJJJJGIJJIJHHHHHFFFFFDDEEDDDDDDDDDEEDDDDDDD
@80J
CGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCG
+
CCCFFFFFHHHHHJJJJIJJGIJIJJJIJHJJJJJJJJIJJJJJJHHHFFFFEEEEEEEDDDEDDDDDDDDDDDDDDDDBDDDDDDDDDD@CDEDDDDDDD
@80K
CCAAGTCATACCAGTGCTGTCTCAATTGCAGGAAAAGAAACTCTTTCATCTGCTGCTAAAAGTGGTACAGAAAAAAAGAAAGAAAAACCACAAGGACAG
+
CCCFFFFFHHHHHJHIJIJHIJJJJJJJJJJJJJJIIIJJIJJJJJJJJJJJJFIJJIJJJJBFHHICHGGIJJJHFFDEEEDDDDDDDDDDDDDDDDD
@80L
CCGGTGTTTGCGGACATCAGCAAAGACCTGGAGAAGATGATGGTTAAGAGGAGAGACTACTTGGACCTTGCGGCGTCCACTCCATCTGACTCCCTGATTT
+
??;D==@DDD>DDEDEDCEE<*C?CDDDEDCDAEIDDECEIEI=BCBCECDAC9@17=CAAADDD@A@>AA??=?;>??:4<9>>A>>AAA>A<<A<>AD
@80M
TGTCTACAAGTTTGTGTGTGATCCAGAAGCCCTTTTCTCCATGGCCTTTCCAGATAATCAGCGTCCACTGCTGAAGACAGACATGGAACGTCACATCAACG
+
@@@DFFDFDFFHHJIJFEFGHIJJJIJIJJJJJGIJJIJIJGIJJJJJIIHIJHIIJJJJGIDHIJIIJJFGHHHHHDDFFEECECEDDBBD?@CCCDDDD
@80N
CAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGG
+
CCCFFFFFHHGHHJJJIJJJJJJJJJJJJIIIJIGIIJJJJIJJGJJJJJJIJJJJJJJJIGIHHGHF?DFDFFEFEDDDDDDDDDDDDDBDCDDDDEDDD
@80O
CACCGCCCAGCCCACTCAAGGATATGCATAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGG
+
CCCFFFFFHHHHHJJJIJJJJJJIJJJJIJJJJAHIJIJJJJJJJJJJIIJJJJJJIHHHGHHFFFFFEEEEEDCDDDDDDDDDDDDDEDDDDDEDDDDDD
@80P
CAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATAT
+
@@@?D<3=2C?DFEAFGECDHHIGEHHEB;FEBEGDDFG7FBHGGCHGCHCFHCHIG>FGIGGGHFEH>BEEEECCC>CCC?@?BBCC:>A@:@CA>AC
@80Q
GGAAGATGTTCAGCGTAGAGTCGCTGGAGCGGGCGGAGCTGTGCGAGAGCCTCCTCACTTGGATCCAGACATTTAATGTGGATGCACCATGCCAGACCGTG
+
;;@DDDDDFH?<?EFFBHGE?@FF:E<CFCHDE6AD6<8(5(::8=BB@<89?BC9A83:@C@AC9@AA82:>C::@C(4>(4>(:AA?ACCCC@BBBB5?
@80R
ATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCC
+
@@@=DDADDAFDF<:EBFGH??CFBGGF4<CGAFGI@@@FB:'@AA>EH@C==AA??@CBDCA>@C>BBBBBBBBBB?CC>CCBCCCCCECCC>?AC?@B
@80S
CCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAAC
+
CCCFFFFFHHHHHJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIIJJJJJIJJJIJFHHFFFFFFEEEEEEEDDDDDDDDDDDDDDDDDDD
@80T
AGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGG
+
?@<DDDDF<>CBFHBEBCIHFBFEGGEFFD>FGH@>DB<BG>GHIIIIIE@GH=;AEEFDEFCC@ACECC@CC;@CACD@CA@CCCACCDCDB4+:A@>18
@80U
GAAATGTTAGAAAAAGAAAAGAATGCTGCGTTAGACAGAATGGCTGAATCACAAGAAGCTGAATTAGAGAGGCTGAGAACACAGCTTCTATTTAGTCACG
+
BBCFFFDEHHHHHJJJJJJIJJJJJJJJJJJJIJIJJJJJJJJIJJJJJJIJJJJJJJJJJJJJJJHHHHHFFFFEDEEEDDDDDDDDDCDEEFDDDEDD
@80V
GAAAAGTCTGAGGGTCCTCTAGGCTCCCAGGAATCTGAATCTTGTGGTCTGAGGAAAGAAGAGAAGGAACCACATGCAGACAAAGATTTCTGCCAAGAAA
+
?;=DDDDDBDAD?A2<<AI??:CA?ACEF>?CFGAGDBG<DD@G??D?9BF>D;F@>BFF=7@EFIFDEEFF?D@;;;;B>@@BA5>ABBABBBAABB??
@80W
TGTAACTCCTTTCCTCCTTTGCCGACGATGCCAAGGGAAGGACGTCCTATGTACCAACGCCAGATGTCTGAGCCAAACATCCCCTTCCCACCACAAGGCTT
+
@@@D?DBDADDDFHGFGAHAECCGHGGIGIHHEEEGIFIIBBCF';F;@A=@DCHACEEFCCCA>>;>>@C>C9AACBBCCCBB9<CA<CB@BBCC?@BCC
@80X
CCAGATAGCAGCTACCCCATGGACCACAGATTTCGCCGCCAGCTTTCTGAACCCTGTAACTCCTTTCCTCCTTTGCCGACGATGCCAAGGGAAGGACGTCC
+
@@@DBDDDBDHHDIIIIIIGIIIICFEGGEIIEHIIIIIIIIIEAHEGGIIFHICHAEHEFFFFFDFFCEEEEEDDDDBDDD<@BDDDBDBBA?B@BDBDD
@80Y
CAAAAGTCCTCCCCTTGGAGGGGCACAAACGATCAGTAAGAATACAGAGCAACGGCCCCAGCCAGATCCGTATCAGATCCTGGGCCCGACCAGCAGTCGCC
+
C@CFFDEFAFDHHIGEIGJCGEGIGJIIJJIIIEHIFFGGGDCEFHGGGIJJJIAEFFCCDDDDDDDDCBBBBBEEACCA::C?@DDDBDBD?1<?CD<BD
@80Z
GAGTGCATTACCCAAGGTCGTGTTTTGGAGCGGCCCCGAGTCTGCCCCAAAGAGGTGTACGATGTCATGCTGGGGTGCTGGCAGAGGGAACCACAGCAGCG
+
?;?ABDD8FFDHD>DFBCHHFFGEFGEDFHCBHIEDAEBE;;CCCEHEHEBE9;A;=;@DB?A@?CCC,5:>CBB>BBCCCBC?8A@BBB?@B?A?B?B19
@810
CCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAAC
+
CCCFFFFFHHHHHJJJJJJIJJIJJJJJJJJJIJJJGIJJJJJJJJJIJJJJJJIJJJJJJJIJJHHHFFFFFFEEEEEEEDDDDDDDDDCDDDDDDDDD
@811
CCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGCACCTGGGTGCTACCCCATGCAGCCAGT
+
(;;1(=8@@8=:)9:)((3/((:<=>>?=?<95><5=3=7;;)6;>>1=>=)..)<11=?))6=16;8;3(,9(3226765,'2::59<<6;;/(+488(8
@812
AGCAGAACAGAAGGCTGTATGTTTGAAAAGGGCCCCAGGCAGTTTTATGATGACACCTGTGTTGTCCCAGAAAAATTCGATGGAGACATCAAACAAGAGCC
+
@@@FFDFFHFHHHIJIJGHIIJIGIIJJGJJJJJJGIJIIJIGIGIIGIJIIIIIIIIHHJEGIHHHHHCDFFFFEEEDEEEDCBDDDDDDDDCBDDDDCB
@813
CTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACT
+
CCCFFFFFHHHHHIJJJIJJJJEHJJJJJJJJJJJJJJIJJJJJJJHIJJJJJJGJJHHHFFFFFEEEEDC>BCCDDDDCDD>CCDCDDDDEEDDDDDDDD
@814
GTCGTCCATGTACAAGTACCCTTCTGACATCTCCTACATGCCTTCCTACCATGCCCACCAGCAGAAGGTGAACTTTGTCCCTCCCCATCCATCCTCCATGC
+
@@CFDFDFHGHHHJJHHHIIJIJJJIIIHIGCFHEIIJJGIIGIJIJIJIJIJJJGGIIIGJIIJJJJCGEHHHGHHCCDFBEDDDEDDDDDCDDDCCDCD
@815
AGGACCTAAAGGTGTATATCAAATCAGCAAACAAATCAAAGCTCATGATGGCAGTGTGTTCACACTTTGTCAGATGAGAAATGGGATGTTATTAACTGG
+
=?@D?;D?ADFD<C:ABFHEFHIFIIIFEFEIEDGGIGFDGEBBDFGDB?DFFFBD?BDFIIICEEAF;=@EFEEFFFAEEE@BDD@@>ABDCDDBBBB
@816
GCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGC
+
;<?==@DDB?1C?<FF>EFHHCHII4CGFE;DFG@G@>:67?:B8BAF;=DECIFFFF3=@@;8>>>@??@??BB??B>:@B(>@AA>BB3<@B?8582<8
@817
CACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGC
+
CCCFFFFFHHHHGIIIJJCHIIIJJJJIJJFIIIJGJIIIJJGIIJJIJJJJJIIJIGJIEGIIGHGHGHFFFFFDEEEDDDBCDCCDDDDDDDDDDDD
@818
AACAGGGCTTGCCCTTAGAAGCCGCTACTGCCCCTGGAGCTGGTCATTACGAGGATACCATTCTGAAAAGCAAGAATAGCATGAACCAGCCTGGGCCCTG
+
CCCFFFFFHHHHHJJJJJJJJJJJJGIIGGGJJJJIIIIJGIIGIIJJJJJJIIHFHHHFFFFFFFFEEEDEDCDDDDCDDEDDDDDDDDDCDDDDDDDD
@819
GTGAATATGGCATTCTCTCAGTCCAACCCTCCTTCGGAGTTGCACAAGGTCCACGGATCCAGAAACAAGCCCACCAGCTTGTGGAACCCAACGTACGGCTC
+
;:;D;B?ACCCDFHH@A@A<EDHGBCHIIGCFGEDAD1:0???DBD>;B?DFGHA8;4AE=>AHH;?BB?;;;;9?5;>AC<:<CACBBBAB?288<9&5>
@81A
AGAAAACAGGGAATTTTTGGGAAATATGAAAAGCCAAAATTTGTGCAGTGTTTAGCATTCTTGGGGAATGGAGATGTTCTTACTGGAGACTCAGGTGGAGT
+
CCCFFFFFHHHHHIJJJJJJJHIIIJJJJJJJJJJJJIJJJJFGIGGIHHDFHIJJJJJGGHIGJJIHHHHFFFFCDEEDDEEDDDDBDDDDDDDCDDDD@
@81B
GAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACT
+
@@CDADFEHHDHFIGGHHGGIGIAFEGHHEHEHHIGHBFDGFGIIIGIIGDHIGGHECEEGIHEEH?EEFFEEE@CECBDCCCDDDCDBDBDDCCBDADD
@81C
GGGGAGCCCCGGACCGAATCGGCTCTCTAGGCCGTGGAGCTTGCCGTCCCACCTCCGTCCAAATCGACCTTTCCTTTCTATCCCCAACCACCCCTCAACCC
+
@C@DFDABFFHHHJJJGIIJIFIGHEDGGB@GCG;AAHCDBFFDECD@BDDDD@BA@9?<BDDD@BDBDBACCAA>CDCA>CCC@CBDDDDDDDBD8ACDD
@81D
GGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATAC
+
@CCFFFFFHHHHHIJJJIJIIIIJJJJJJJJIIJJJJIJJIJJIJJIJIJIJJJIBHJJGJGHFFFFEEECEECDDDDDDDCDBDDDDDDCBBDDCDDDEC
@81E
CTTTGAGGGCCAACAGCCCACCCTTGAGGTCCAAAGAAAATCAAGAACAGAGCTGTGAAACCGTAGGGCATCCCAGTGATCTGTGGGCAGAAGGTTGCTTC
+
CCCFFFFFGHHHHJIJJJJJJJJJJIIIJIIJJJJJJJJJJJJJJIJJJJIJJJJFGIJJJJHEHFFFEDEEEDDDDDDEEEDDDDDBCDDDDDCDDDDDD
@81F
ATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGAT
+
@@CFDDFFHDD?BEGEGHIIC@EEHBBFHHGCFFHDBED@AHHIGIIIBECHIGHEEDEEHC?>>B?BDA@@5>AC>?::,3(,,8>@CC<4<CC>>@CD3
@81G
GGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACAC
+
CCCFFFFFFHHHHJJJJJJJJJJJJJJJGHIJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJHHHHHFFFFFDDEEDDDDDDDDDEEDDDDDDD
@81H
GCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTAT
+
CCCFFFFFHHHHHJJJJJJEHHJJJIJJJJJJJJJJJJJHIJJJJJJHIJJJJJJJIJJIJIJJJJHIHHHHHHFFFFFEEEEEDDDDDDDDDDDDDDDDD
@81I
TAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACT
+
@@@FFFFEDDFDBFGIIDHIAFFHEHIGEGGGDGIIIIEGHGGHIIGGHEEGFGGHGIIEGIIIGGGFHCHDFDEFEEDEEDCCDDCCCDCDC?BBBB@D
@81J
CTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTAT
+
@@@D;DDAF?FH?BCFC=<BCBHBCGI@0?GBDHGIII@?67@CEGCEG@GE)=E@?;>BBB>@C>>AB;?@CCC@C@@AC:AA?8?A?BB808?>?B<AC
@81K
AAGCTCAAACTGGAGTGGGCATATGGTTATCGAGGAAAGGACTGTAGAGCTAATGTTTACCTTCTTCCGACCGGGGAAATAGTTTATTTCATTGCATCAGT
+
@C@DDDEFDDFHHGGAEGGGCCFHHICBF<?FDHHIIIIIIGIG@FFGGGHGGBFFEHGIIIIIIIDGEA:?C?DDDDACCDDDDDDCCCDDDACD>:@CA
@81L
TGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGG
+
@;7?BDDDHAHHDG?EHGFIIDGIHIIGGCGCHGBHCFHIDGHEG=::4@CEHIHHHEEED?AB?CCC>C@3@CCCCCBCCCCCACAACCCCCACCC@CBB
@81M
CCTGACGCAGGCTTCCAACCCCGTCGTCTGCACGCAGCCCAAATCCCCATCCAGCACGCCAGTGTCCCCACTGCATCATGCATCTCCAAACTCAACTCAT
+
@@@FFFFFHGFFFGGIIGGGIIGIIGAFFIGDHGG@FGIGIGHIGIHHHEC@D?CEE39?@;5>5@CCDDBACCD@C>>@>CDC>ACDC:8:>AAC@AAC
@81N
AGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAAC
+
??+4=22=AC?DDII?:2CA<F:A3F1F9:111C?:?9:9:990B9BD2D@6;64-)=C=))).>C777?77)..;)6>AABA;5,(5;98:5:AA=<(+2
@81O
TGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGAC
+
@?@DD?B;DDAD?FGIGD@?GFA=9CC?BDGIBEDFHC9B8===B8.8=FH;CDG7C=?;;AEC?2;3;339>>:>?@18<88888?39?C:>>@CA>
@81P
GGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCC
+
BCCDDFFFHHHHHJGHIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHHHHFFFFFFEEEEDEDDDD@CDDDDDDDDDD
@81Q
TGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTAT
+
CCCFFFFFHHHHHJIIJIJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJIJJJJJJJHHFFFEEEEEEDDDDDDDDDDDDDDDDDDDDDDDCDDD
@81R
GTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTAC
+
CBCFFFFFHHHHHJJIJJJJJJJJJJJJJIJJJIHIJJJJJJJJJJJJJJJJJJGIIJJJJJHGJJHHHHHEFFFEEDDEDDDDDDDDDDDDDDDDDDDDD
@81S
TGAATATCCTACTCTTCATGGGCTATTCCACAAAGCCACAACTGGCTATTGTTACCCAGTGGTGTGAGGGCTCCAGCTTGTATCACCATCTCCATATCATT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJGHIBFGIIJJJHHHHFFFFFEEEEEEEDDDDDDDDDDDDEEE
@81T
GAAAAACAGGCTAGCTATGAACTATGATAAACTTAGCCGTTCACTCCGCTATTACTATGAGAAAGGAATTATGCAAAAGGTGGCTGGAGAGAGATATGTCT
+
??@DFFDDHHHFDGGGIGIGHIAH><F@FHHHHCBFCDGCFB@BFF;BA?BGIHHGFHJHHC@@CECHEHHEEFFDCEEDC@?ADDDABC@???A@CDDBD
@81U
GTGGAGCCTATGGAAAGGTTTATGCAGGCACAGCAGCGGACTTCTTAGGAGTTGGAAGTGGAGATGTCAAAGAAACAGGGAAGACTTTGAAGAAGGGTTCC
+
-0(:(.)8;)2.)2.2(=4))2.))).(((93)=38(0-3(-7)/.))).)..))).8.)).(6.)...;(((6(-9;((2(((530(,(7:(++2:6(+(
@81V
GGAAACCTCGGATTCTTTTTTCACCATTCTTCCACCCTGGAAACTCTATACACACACAGCCGGAGGTCATACTGCATCAGAAC
+
@@8DD8DDFHFFHIGHIIIIIGIIIGIIIIIIIICGGIIIIIFIII4DHIIGHIIIIAEGHHE9>C?CCCECCDCCC:CC@CC
@81W
CCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATT
+
CCCFFFFFHHHHFJIJJJHIJJJJJJJJJJJJJJJJIJHJJJJJJJJJJJJJJJJJJIJJJJJJIJJJJHHHHHFFFFFEEEEEEDDDDDDDDDDDDDDDD
@81X
GCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACA
+
CCCFFFFFGHHHHJJJJJJJJIJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJGHHHHFFFFEDEDEEDDDDDEDDDDDDDDDDDDDDDDDDDDD9>BDD
@81Y
CTCACTGCTCCTAGAGCCCTCTTCGCTGACTGCCAATATGAAGGAGGTACCTCTGTTCAGGCTACGTCACTTCCCTTGTGGGAATGTCAATTACGGCTACC
+
CCCFFFFFFHHHHJJJJJJJJJJJFHIJJJJIJIJJJJJJJJJJIJIDFHIIJJIJJJJJJJJJJJJHHHHFFFFFFECECDDDDDDEEEFEDDDDDBDDD
@81Z
TCGTACAAACTGCATCAGGAGATATGCAAACATATCAGATCCGAACTACACCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATGACATCTCCTGTGACT
+
B@CDDFFFGHHHHJJJJJHIJJIJIJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJIJJJJJJJJJJJJJJHHHHFFFF@DE@CEEDEDDDDDDDDDDDEDD
@820
GTAGCTCTTCTGGATGACCCTTCAAATTCTCATTTTATTGCCTGGACTGGTCGAGGCATGGAATTTAAACTGATTGAGCCTGAAGAGGTGGCCCGACGTTG
+
@@@DDDDDFHFHFEBGHIICGEIIIIIDHIIGIIGIGGIIGHEHIGIGDGHGHGGGIGAGHEHGIIIHHEEEEBDEDEECCC;@C<??;?B?A<=BBB58A
@821
CGAGCAGCTATGGACAGCAGAGTAGCTATGGGCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCT
+
???DD12:C:DAD4C+22A3AE<C9999?BB)::8:?D8?D;DB?9*///?9@@8..68A;@36(=)..;;@7.;@>3=;?5>>A:,:=>AAA4>???80+
@822
GACAAGTGCAAGCCTATGTCCTATGAGGAGAAGCGGCAGCTCAGCTTGGACATCAACAAGCTCCCCGGCGAGAAGCTGGGCCGCGTGGTGCACATCATCC
+
@@@D?DADHHHHHJIIGEDDHGIJIHEGHGGI@BHIJIGDCGHE@BGIJGIGEGGIJIGEHHHFFFBC?D?BDDCC>CC@DD@<@-5>28>>@CACCCCC
@823
CTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATG
+
CCCFDDFFHHHHHJJJJJIJJIJIIIJJIGHIJJJJJJJJJJJJJJJIJJJJHHHHGHEFFBBCEEEEEDDDDEDDDDDBD>CCDDDDDADDDDDDDDDDD
@824
GTTTTGAGGCGTCTTGCAATCTCTGAAGATCATGTGGCCTCAGTGAAAAAATCAGTCTCAAGTAAAGGCCAACCAAGCCCTCGAGCAGTTATTCCCATGTC
+
CBCFFFFFHHHHHJJIJJJJJJJJJJJJJJJJJJIJJJJJJJJHJJJJJJJJJIJGIJJHHHHHHHFDFFDDDDDDDDDDDDDDDDDDDDDEDEEDDDDED
@825
CACAACACCATGGTTGGCAGTGCGGCCAGCCAAAGCTTTCCCCCTCCTCTGATGATTAAACAGGAACCCAGAGATTTTGCATATGACTCAGAAGTGCCT
+
@CCFFDFDHHDDHHIIIIIJHHIGIJJIIGIIIJIJJJJJJJIJIIJJGIJHHHGCEHDFEFFDEDCDDDDBDCDCCDDCEEDDEEDCDDCCDC:@@CA
@826
CTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACT
+
@CCFFFFFHHHHHJJJJJJJJJJJJJJIJJIJJIIJJIJIJJJJIJJJJJGJJJIJJIJJHGHHHHFFFFFFECDDDDDDDDDDDDDDCDDDCDDDDDDDD
@827
GGTGTTTATTTGCATCCACCTGTCCAGTTGCTCTGCTGTCTTGTGTTTTTGCAGCCTCTACAACCCCACGTCAGAGTGTGGGATTCTGTTACTCTATCCAC
+
?@?DADDDAFHBDIGIGIJJGIJGHIIEHHHJJEGICB11?CFDGGGHJJB@BFGHHIEIGIJGIIIAEHEHEFDD;@@ABDBCCDCACCDDDDDD;ACCD
@828
GATTCACCGAACGCCGGGTTATGTCAGCTGCTGCAGTGGGTGATGGGGCCGCAGATAGGGCGGGGGTTGGTGCTGAGCGCAGGGGGGGTGCGATGGAAGGC
+
(;9;(;)4((0;(((((<(<7).).)0)).)0...9)))('-.)))((''','3'((((8(35&0:05:9((((+(+(&005:&)095&)(&&+)&((+(+
@829
GCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTC
+
@@@DFAFFHFHH?GHHIIGGIJGHGIJHEHEIJJIIIIJIJIIGIGJIIIICEHCHGHHHF?>AEEBDCCCB;ACC>CCCDEEDDDDDBDCDDDDDDDCC
@82A
GCTGGATGAGATGTATGGGCAGCAGATAGTGCAAATGAAACAAGAATTAATAAGACAACACATGGCACAGATGGAGGAAATGAAAACACGGCATAAGGG
+
CCCFFFFFHHHHHHIJJJJJJJJJJJGIJFHHJJJJJJJJJJJJJIJJIJJJJJJIJJJJJJJJIJIJJIHGHHFHFFFFEEEEEEDDDDDDDDDDDDD
@82B
CAGATCCAGCTGTGGCACTTTATCCTGGAGCTGCTGCGGAAGGAGGAGTACCAGGGCGTCATTGCCTGGCAGGGGGACTACGGGGAATTCGTCATCAA
+
@C@FFFFF?DDFDEFEBEA>FHDHHGIIIGHIIIII9DHHGDGAHAFCFHCFHIIGHF>>CEEECCCDBD@@BDDDDDBDCBDDD<9?CABC@B<CCC
@82C
GAAATGTACATAAATAGTTCTCAGAGAGTAGAATCAACTGTGATTCCTGAATCTACAATAATGAGAACTCTACATAGTGGAGAAATAACCAGTCATGAGC
+
CCCFFFFFHHHHHJJJJHIJJJJJJJJJGHIJJJJJJJJJHIJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJHHIIIJJHHHHHHFFFFFEEEEE
@82D
GGACCCCCAGGCCATCCGTGGATAATGTGCACCATAACCCTCCCACCATTGAACTGTTGCACCGCTCCAGGTCACCTATCACGACAAATCACCGGCCTTCT
+
=71+2++?)?A3AA3AB6++1@<AA4*:?BB<ABBB<=7=5(7/95;=>ABABBBB==4)7=)4==@=>??;;;???:=;==;=/9;;:3:;;<==;3::8
@82E
TCGCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGCTACCACCACTGCTACAGTCACC
+
9;(--(:67>:)9))).:>4).)38@>@??8=3-<9>3<>)/<>(:=1>93:31))9/'':(669=49;-49<=22;(5(708,8(26:<:((3:/(8<:
@82F
CGAGGATCACTTCAGCTCTGGCAGTTTTTGGTAGCTCTTCTGGATGACCCTTCAAATTCTCATTTTATTGCCTGGACTGGTCGAGGCATGGAATTTAAACT
+
CCCFFFFFHHHHHJIIJJIJJIJJHIJJJJJIJIJJIJJJJJIJJJJJJJJJJIJJJJJJJIJJJJIJIIJJJHHHHHFFFFDDDDDDDDDDDDDDDEDDD
@82G
ACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCT
+
B@@DDFDDFHHHHJIJJIHIIGHIJJJJJGFIIJIGIJJHGJEIJGIIIIIJGEHGIJIJIJJJFIIGGEHHFFAACD@CDDDDDDACCDBCDCBACCDD
@82H
CGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGC
+
@??D?D>?C88CFG<FDEHGIIIF<?<EE3CDFG33B?FH:FG28;@F@FHE=@:CC==?A=<B9;@958?9???CC:>8(:A>C34>C>?89??<0(8?
@82I
CATGATTCTAAATAAGTCTTTACACCCCCAAGTATGTTCTGTAGATTTCGAGGCCAGAGTCCTTTAGCCCTACTCAGGTTAAAATGATGTTTTGTTTTTC
+
@CCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJHJJJJJJJJJJJJIJJJJJJJJJJJJJIJJJJJJJIJHHHHFFFFFFEEEEEEDDDDDDEDDBDDDDD
@82J
CTAAGCCCGGAGCCCGGCGCTTTCCCCGCAAGATGGACGGTTTCGCCGGCAGTCTCGATGATAGTATTTCTGCTGCAAGTACTTCTGATGTTCAAGATCGC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJHHHHHFFFDDDDDDDDDDDDDDDDDDDDEDEEDDEEEEEEDDDDDDDDCDDEEDDDEEDEDEEEDDDDDD
@82K
CTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHIJJJJHHHHEEFFFFFEEEEEEEDDDDDDDDDDDDEDDDDDDDDDDDBDDDDDDD
@82L
CCTACACCTCAGCAGTTACAAGCCTTCAAAAATGAAGTAGGAGTACTCAGGAAAACACGACATGTGAATATCCTACTCTTCATGGGCTATTCCACAAAGCC
+
CCCFFFFFHHGHHJJHIIJJJGGJJJJJJJJJIIJJJFHIJJJHHIJIJJJJIIIJJJIJJJJICHHHGHHHHFFFFFFEEECCDDDDDDDEEEDDDDDDD
@82M
TATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATC
+
CCCFFFFFGGACFGCIIGHGIIIJIIC?EEGIIBHJJFHHG>GGFHIIJIGDDHGIJJG@GEHGHHGHHFFFEFFDECEEEDD@ADDBDDDDCDDECDDD
@82N
ATTGCCGGCTCCTCCAAGATGAAGGGCTTCTCGTCCTCAGAGTCGGAGAGCTCCAGTGAGTCCAGCTCCTCTGACAGCGAAGACTCCGAAACAGGTCCTGC
+
CCCFFDFFHFHHHIIJJGGGHJGHIEGHGDGGGHHIGHGGGIIGGEGB<EHFCCA?DDDD@CAECCE>CCCCC>CACDDDBBDCCCCDDBBBACB3>ACCD
@82O
CCCACCACAAGGCTTTAAGCAGGAGTACCACGACCCAGTGTATGAACACAACACCATGGTTGGCAGTGCGGCCAGCCAAAGCTTTCCCCCTCCTCTGATG
+
@??DDDDDFDC?FGBFIGBHGIIAH9C?CFHF@GGADD??0?DAGIGGHC@CCHHIA@E7=A<BEF6;AABBBB9?@AC??C@C@@CCC<>B?C?C:4+:
@82P
ACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJHIJJJJIJJJJJJJJJJJJJDHIJJJJJGIJJJJJJJJFHHGFFFFFFEEEEEEDDDDDDDCDDDDDDDDDDD
@82Q
CACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGC
+
CCCFFFFFHHHHHIJJIJJJJJJJJJJJJJJIJJJJJIJJJJJIJJJJJIJJJIJJJJJJHIJJHHHHHHFFFFFDDEEDDDDDDCDDDDDDDDDDDDD
@82R
GTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGC
+
@B@FFFFFHHHGHJJJJJIJJJJJJIJJJJJIIJJIJIIIJIIJJJJJJJJJIIJJJJJJJJJHHHHHFFFFFFEEEEEEEDDDCDDDDDDDDDDDDDD
@82S
CAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJIJJJJJJJIJJJJJJJJJJIJJJJJJJJHIIJJJJJHHHHHHFFFEFEDEEEDDDDDDDDDDDDDDDDCDDDDCD
@82T
AAACCGAGTTGCAGTCCTGGAAAATCAAAATAAAACTCTAATAGAAGAGTTAAAAACTTTGAAGGATCTTTATTCCAATAAAAGTGTTTGATTCCTAAGA
+
CCCFFFFFHHGHHJFHIJIIJIJGIJIIJJJJJJJJJIJIJJJJJJGCHHIJJJJJJJJJIJIGGIIHIJGHHGHHHHHFFFFF6>@BCEEDDEFDDDDD
@82U
CCAGCTTTCTGAACCCTGTAACTCCTTTCCTCCTTTGCCGACGATGCCAAGGGAAGGACGTCCTATGTACCAACGCCAGATGTCTGAGCCAAACATCCCCT
+
??7DDDDDD>DD<EEEDEEDE::3<CEFEFI<EEEF9E<C?:?@7?BCEI>=7C>@CDDD@8?(;3;AD>AAA?????89>ADAAA4:>AA><81>>A??<
@82V
CGAGAGGGAGACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTAC
+
BC@FDFFFHHHHHJIJJGIJGIJJGGIIEHIDHHBFHIHJIIHHHHHHFFFDDDDDDDDDDDDDDDEDDDDDDEDDDDDDDDDDDDDBBDDBDDDDDDD
@82W
AGGACACAGTGCCTCTTTCTCACTTTGATGAGAGCATGGCCTACATGCCGGAAGGGGGCTGCTGCAACCCCCACCCCTACAACGAAGGCTACGTGTATTA
+
CCCFFFFFGHHHHJJJJJJIIJJJJJIHIHIJJJJJJJJFIIIJJIJIJJIJJIGIGIFFDDEDEDDCDDDDDDDDDDDDDDDDDDDDDDCDDAADCDEE
@82X
CTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTAC
+
;??:B>D;FDDDFBB9BDDEFC<FD<E9AFEEFD@ADBDE<;6B2;56@=CEEEFC>C:BDB;7=9@;;>;;>(5>3555>@A<?@?3:3(4:??8851:(
@82Y
CAGGGGCATTTTCACCCGCGTCATTGCAACCTGAATTAACCCGGAGGGAGCCAAAGACCTCATCCTCAAGAAACACAACAAGCCGGTCATCCATGACTAC
+
((0((0(:?).)))):38(>--(.:)))))0)03<>8..))(-''-3''5'(60(((((7((,,2((7;0(7(+(+886(+(++)5&&0(+(((+((+58
@82Z
ACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCT
+
CCCFFFFFHHHHHIJJIGIJJJIIIIJIEFGHJJJJJIIJIIJJIJIJ?DHIJIJIIBHIIIIJJJHGHHHFFFFEEEEEEEDDDCDBDDDDCDDDDCDDD
@830
CCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGG
+
?;1A?DDD:<DFHGDGHAHDG@BCHGIIG?BFDGHEBCGEHBDHGBBBEDGIC@A88AEH@=>C;C>>5?C@C=@>CC;@;;>-;@:ACBBCCCCBCC>@>
@831
CCTGGCTTACATGAACCACATCATGGTCTCTGTCTCCCCGCCTGAAGAGCACGCCATGCCCATTGGGAGAATAGCAGACTGTAGACTGCTTTGGGATTACG
+
@@;A;BDDDCHD?EDFD?FHIEICHGA<ACHE?F?CFDG@GDGCBDED?8CBFAAA@EG:=?ACEED65>BCCCCCCCBCC3>@CC>C?>CACCB<>?@CB
@832
CTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTC
+
CCCFFFFFHHHHHJJJJJJHIJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJHHHHHHFFFFFFFEEEDEDDACDDDDDDDDDDDDDDDDDDDDDDDDDDD
@833
CCGCCTGATGCTGCAATGCTGGAAGCAGGAGCCGGACAAAAGGCCGGTGTTTGCGGACATCAGCAAAGACCTGGAGAAGATGATGGTTAAGAGGAGAGACT
+
BC@FFFFFHHGGHJJIJJIJJJIIJJJJIJJJJIJIGJJJIJJJJJJGEEHHFFFDDDDDDDDDDDDDDDDDDDBDDBDCCCDEDDAACCC@CDBDADDDD
@834
GGAAAATCAAAATAAAACTCTAATAGAAGAGTTAAAAACTTTGAAGGATCTTTATTCCAATAAAAGTGTTTGATTCCTAAGAAAGAAAATATTTTTGTGG
+
@CCFFFFFHHHHHJJJJJJJJIJJJJJJJIJJJJJIJJIJJJIJJJJIIJIJJJIJJJJIJJJJJJ8BBGGIJJJJIHIJEHHHFHFFFDEFFEEEDBDD
@835
CTGGACAACATGATCCGCCGCCTCTCCCCGGCTGAGAGAGCTCAGGGACCCAGGCCGCACCAGGAGAACAACCACCAGGAGTCCTACCCTCTGTCAGTGTC
+
@@CFFFFFHHHGHJJJJJIIJJJJJJJIJJJJIIIJJIGIGIJIIHGHHFFFDDDDDDDDBDDDBDBBCDDDDBDDBDDB@?CDDDDDDCDCDDDDD@CAD
@836
CTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTAT
+
@C@DFBFDDFBDFHIBGIEDGHEHHGGCHBD@BFFGGICHE7;F@;CADD;;CAEEE?D?B>@;>@CDBDDDCDDDCC;::>AC?B?BBBDDBDDDDDDDD
@837
CTTTGGCAGATGAAGCTCAGTCTCTGAAAGATGAGATCGACGTGCTGAGACATTCTTCTGATAAAGTATCTAAACTAGAAGGTCAAGTAGAATCTTATAA
+
CCCFFFFFHGGHFGHIIJJJHJJJJJJIIIJJJJIIJGJJIJIIGGGIICGIJJIIJJIIJJJJAG=@CCEHHDEEDDFDDF;6>@C(;;ACCCCCCACD
@838
AGGAAGTGGCCTGTGTAGTGCTTCAAGGGCCAGGCTGCCAGGCCATGTTGCAGCTGACCACCCACCTGCAGTGTACCGCCGGAAGCACCAGGAGCTGCA
+
CCCFFFDDHHHHFHIIHIJIIJJJIJGEHIJJJIIJJFHIJIIJJBGGHJIJIJJJGJIJIJJGHHHDFFFFFECDDCDDDDDDDDDDDDDDDDDDDDD
@839
TCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCT
+
<<;D;?DD)<ADDEEIIEE4CDFI@>EE?EEACDBADE9<?DDEIDEEEIEDDDDDD7=5A;C?=C>D>@;@>AA<>>@>>>AA>;AA9>A?AA>>99>8>
@83A
GATGTTTTGAGGCGTCTTGCAATCTCTGAAGATCATGTGGCCTCAGTGAAAAAATCAGTCTCAAGTAAAGGCCAACCAAGCCCTCGAGCAGTTATTCCCAT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJFHJJJJJJJIJJJJJJJJJJJJHHHHHHEFFFFEDDDDDDDDDDDDDDDDDDDDDDDEDEEDDD
@83B
GCCAAGGTGAAGAAAAGACTGAGGGTACTCTAGGCTCCCAGGAATCTGAATCTTGTGGTCTGAGGAAAGAAGAGAAGGTACCACATGCAGACAAAGATTTC
+
=;=<++?22?C7>A>=++3<7+?++?+*1**?*??A3?:)*)09>*?>4?<4A.)=A(8;>))/(..7(=()=()7;2(.(.635(;>(-,(9=53(,595
@83C
CAATCATCCACAGAGACCTCAAGAGTAATAATATATTTCTTCATGAAGACCTCACAGTAAAAATAGGTGATTTTGGACTAGCTACAGAGAAATCTCGATGG
+
?1=D?DBD=C;CBEBEFGEGF<B4EACDACHEG?D<?FFD@GF@<9DC@0BD@DBFAD4?9*)./=C8=/7=CFDF))7=;)7?B>>>@A>A;AC;=A;:8
@83D
TTAAACAGGAACCCAGAGATTTTGCATATGACTCAGAAGTGCCTAGCTGCCACTCCATTTATATGAGGCAAGAAGGCTTCCTGGCTCATCCCAGCAGAAC
+
CCCFFFFFHHHHHJJJJJIIJIJJIJJJJJJJJJJJJJIHGHHIJIJJJJJIJJIIJJJJGIGGIGIJJJJJHHHHHFFFFFEEEEEDDDDDDDDDDDDD
@83E
TGCAAACATATCAGATCCGAACTACACCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATGACATCTCCTGTGACTCTCACCTCTCAGACAACTAAGAC
+
@@@DADD8+C??C?C>FBD+AEGD?ABC9??DFFF<D?DDABBD<?3?B;(8B?FF@8@F:F7=@D;7=DA>)=AEFDB??36;;;ABBB(==@@5AA::
@83F
ATTTTATTGCCTGGACTGGTCGAGGCATGGAATTTAAACTGATTGAGCCTGAAGAGGTGGCCCGACGTTGGGGCATTCAGAAAAACAGGCCAGCTATGAAC
+
CCCDFFFDFFHHHGIJJIJEDGHDGGHIJFCEGGDGDCCGEGGIEGGGGHGCGD:CC8=@GI?EDFBBDDDD@?@DDD@CCCCDDBDDDDBDB?@ACCCDA
@83G
GAGAAAGTGCTTGTGAGGCCCAAGGACCCTGAGGGGGTTCCTCCTCTCCTGGTCTCTCAACAGGCAAAACGGGAGGAGGAGCGCAGCCCAGCTGCCCCCCC
+
?;;D?;?DD<,2+2+2A?:CE@?8C8+1@:??;1D6@'-8@8@C7@C;7)=7=C>A3;@3>;A9;=??A;8,8?8&28>08<>;&))88(88(:>128&)&
@83H
CCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTT
+
@@@DDADDAH8CBFHGEG:CBFHIHEEGEGIIIIIIIDEHHIIDDAGIIIIGGIIBEGHGICDHFEHHFFFBFCCA;@CCCCCCCEC?CCCCCCCCC@BCC
@83I
TTTGAAAGCTGAGATTGTTTCTGCATCTGAATCCAGAAAGGAACTAGAATTAAAACATGAAGCAGAAGTTACAAATTACAAGATAAAACTTGAAATGTT
+
CCCFFFFFHHGGHJJJJJIJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJIJJJJJJIJJJIJJJJHJJJJJJJJHHHHHHFFFFFFEEEEEEDDDD
@83J
ATCATGGTCTCTGTCTCCCCGCCTGAAGAGCACGCCATGCCCATTGGGAGAATAGCAGACTGTAGACTGCTTTGGGATTACGTCTATCAGTTGCTTTCTG
+
C@@FFDDFHAFHGGIGHHIGGGIGJJJDIGIIJHGIEGDGIJJJJJIIHGIJGGGIIG;AHFEHFFFFFFEDEECDD@ACDDDDCDCCDDDEDACCCCCD
@83K
GTAACTCCTTTCCTCCTTTGCCGACGATGCCAAGGGAAGGACGTCCTATGTACCAACGCCAGATGTCTGAGCCAAACATCCCCTTCCCACCACAAGGCTTT
+
@@@FDFDFDHHGHFIIGGIEIIJJIIGIGIIJIGIHDHIJHIIFHJJJJJIIIJFGGHEDDDDCDDCEDDDDDDDDDDDDDDDDBCDDDDDD?B<BD@CCC
@83L
TTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGC
+
@@@DDDBD<CCFHEGGHIIIFDAFFCAH3ACEGHAGGI>FBGG@@FDGHHHIGIICGGIG@=C2)?EFC@DDC@:;;3>>CBBCCCCBC:@C:9?<9@88?
@83M
GTCTGATCTTTCTGAACAATTGAAACAGAAACATGGTGAGATTAGTTTTCTAAATGAAGAAGTTAAATCTTTAAAGCAAGAGAAAGAACAAGTTTCATTG
+
C@CFFFFFHHHHHHEHHIEIJJJJJJJIJIIGIGHJ?EFHIJJIJGGIIJIJIJJJIIIJJJGHIJJGHIJGIJGIGIJIIHHHHGFFCFCCCEEEFEED
@83N
TTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGC
+
CCCFFFFFHHGHHJJIIIJJJJJJJJJJJJJJJJJJJIHIIJJJJJIIJJJJJJJJJJJJJIJHGHHHFFFFFFEEEEEEDDDCDDDDDDDDDDDDDDDDD
@83O
GTCGAAAATACCTTCAACACCCAAATTAATACCAAAAGTTACCAAAACTGCAGACAAGCATAAAGATGTCATCATCAACCAAGAAGGAGAATATATTAAA
+
B@@FDFFFHHHGHFIJJJJJIJIJGJFJHGJJJJJIJJIIIJIJJCGGGHICGIIJIJIJIIIGIIAGHHHGHHGDDDFFDDEEDDDDB@@DDEEDDFED
@83P
GATTTCGCCGCCAGCTTTCTGAACCCTGTAACTCCTTTCCTCCTTTGCTGACGATGCCAAGGGAAGGACGTCCTATGTACCAACGCCATATGTCTTATCC
+
18=DD::@DA:@)@@A??CG4C?*?CG;9?DFABEGGEH>BDFHFA@D))/8/(;;@CEEE7(6?5((6,9/55:>(5((535<(&&&((+((((+4(+4
@83Q
GGATACCTGTCTCCAGATCTCAGTAAGGTACGGAGTAACTGTCCAAAAGCCATGAAGAGATTAATGGCAGAGTGCCTCAAAAAGAAAAGAGATGAGAGACC
+
CCCFFFFFH:FHHJJJJJJJJJJJJJJJHIJJJJJGHIJJJJJJJJJJIJJJJJJJJIJJJJJJGJJJJJJHEHHHHFFFFFDDDEDDCBDDDDDDDDDDD
@83R
AACGCCAGATGTCTGAGCCAAACATCCCCTTCCCACCACAAGGCTTTAAGCAGGAGTACCACGACCCAGTGTATGAACACAACACCATGGTTGGCAGTGCG
+
CCCFFFFFHFHHHJJJIJIIJJIJJJJJIJJJJJJJJJGIIIIIIGIJJJJJJIGIDEH@GIHHFFDDDDDCDEEDEDDCDDDDDDDDDDCCDDDDDCCDD
@83S
GTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGC
+
@?@DADBDFDFFFIB:AE;C?@GB:FFC?3?;FFEDDG@FEE@FFFEFFE@B;?EBDBDC>>>B>5>@;>>;>?,,9??BB?@BB8>::4><B?B2<B??<
@83T
CAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCC
+
@@@BDDBBBFFDH=AGGEHFF9AC@BDFGGIEB@D??FFFHHB6?@;'8C@G@==7===?EEE>77?(66@?BCB=;?;>ACDCEC@::A55??>C?285<
@83U
CAAGGATTTCGTGGTGATGGAGGATCAACCACAGGTTTGTCTGCTACCCCCCCTGCCTCATTACCTGGCTCACTAACTAACGTGAAAGCCTTACAGAAATC
+
=;;<?+?=B=7AA<<<22<=3?=AC<ABA3A;BBB:7:=0997==?BAA;7:A/;<>>@@@>55;;;22595=99;5;3958329;?:38:?8=;?=?;;;
@83V
ATTACAGGCTAGTGAAACTCTGAGAAACAGCACTCATAGTAGCACAGCTGCAGACTTACTACAAGCCAAACAACAGATCCTCACTCATCAACAGCAGCTTG
+
@CCFFFFFHHHHFGIEHIGIGG@HHGGGBEGGIIIIJJIEGIEHGIJJFJIIH@FHIIIIIIJJJJDIIJJJHFGGFFFFFFCDCCC@CCDCCBBCBDCDC
@83W
CTTCTGAAGAAATAAAACAGTTAATGGGGACAGTCGAAGAACTTCAGAAGAGAAATCATAAAGACAGCCAGTTCGAAACTGATATAGTACAACGAATGGA
+
@@CDFFFFBHHGHIAGGHEFFEHHIIIIIEFHGIHGEIDHHEGHGHICGIIIIIIGGIIIGIEGCHIEFFFHHEFBBDCCC@CCDDC@CACCCB@BBDCA
@83X
CCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGC
+
CCCFFFFFFHHFFEHGEHIJIIGDEHIEBFHIEHHIJJJIJGGIJIIEIJJJJJJIIJIGHJJGHEEEHHFFFFFDDDBDDDDDCCCACCCDDC>CBDDB@
@83Y
CGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAGGCT
+
@@@FFFBD?FHFBHIIGBHIIEHGGEHIGGG?FFHGIGEAFGBGDHIIGGB@@FCAHHEHGGGHIFFAACCADB?DCCBCBCCCCCCCCCCCCCCBB<A<8
@83Z
CTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATG
+
?7?DA?BDBB?DDB32?<8?@FGEB=DG8B9?<9<0?4DFFCFBF8FFF;??6AD@;.?BC@6(5(;>;?AB<?982(((883@B:3<8982?B@><34:A
@840
ACTGCGTGAGCTGGAGCGCTATGTCACCTCCTGTTTGCGGAAGAAAAGGAAACCTCAAGCTGAGAAAGTTGATGTGATTGCCGGCTCCTCCAAGATGAAGG
+
?@<DDDDDAB?FFG;EAGEDDGH??DFHGGGIG<BFDDGH<FAGDHDGHIGC=EEH>@BBCC>?A@AA;>C;>A>ADDDCCCBB><B?C?CCCC<>ACCCC
@841
ATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCA
+
@C@DDFFDFHHGGIIIJGIJIJJGHEIEGGEIBEGHGHJJEGIFGGHGJGHIIFGABHFFFFDBECCDDDDCCCDCECCCCBDD@BDDBBBBDCCDDC?C
@842
CTTAGCCGTTCACTCCGCTATTACTATGAGAAAGGAATTATGCAAAAGGTGGCTGGAGAGAGATATGTCTACAAGTTTGTGTGTGATCCAGAAGCCCTTTT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJDGIIJJJIJHIHIEHHHHHFFFFFFEEEEEACCBADDEEDDDDDDDDDDDDD
@843
CTCCGAGTCCCACCCGAAGCCATCCAGCCCCCGGCAGGAGAGTACACGCGTGATCCAGCTGATGCCCAGCCCCATCATGCACCCTCTGATCCTGAACCCCC
+
@@@:A=DDHFDF>GDCF@EGGEHFGH<:BDHIGEHABHAC=C77?>CBC?BBBCDCCCC<@CA:>:9@?@BBB@<?>>CC@@>?BBCA@4>C3(::>@@@B
@844
CTCAGGGACCCAGGCCGCACCAGGAGAACAACCACCAGGAGTCCTACCCTCTGTCAGTGTCTCCCATGGAGAATAATCACTGCCCAGCGTCCTCCGAGTCC
+
@@@BDBBDBCFDFIIIGEIIGFDHFH?FFBHEHGIGIECHG=FHCCHIGCEC@=B>B@@;@>ACA;CCDDDDDDDADCCCA@ACDC??>BBB?@?@B92<A
@845
AGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGAC
+
CCCFFFFFHHHHHJJJJJJJJJHHIJJJJJHIJJIJJJJJJIJIJIJJJHIIJJJJJJJJJJJJJJJJHHHHFFFFFEEEDEDDDEEDDDDDDDDDDDDBD
@846
CACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTC
+
CCCFFFFFHHHHHJGJIJGIJJJJJJJJJJIGGIJJJIJJIIGHIJJJIIJJJHHHHHFFFFACCEEEDDBDDDDDDDDDDDCDDDDBDCCCDDCCDDDCD
@847
CAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGG
+
CCCFFFFFHHGHHJJJJJJJJGJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJIHHHHHHFFFFFFEEEEDEDDDDDBDDCDDDDDADDDBDDDDDDD
@848
CGACTTTGAGACCCTGAAGCCGTCCACACTGCGTGAGCTGGAGCGCTATGTCACCTCCTGTTTGCGGAAGAAAAGGAAACCTCAAGCTGAGAAAGTTGATG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJHHHHHFFFFFEDDDDDDDDDDDDDDDDDDDDDDDDDCDDDDDCDDDDD
@849
ATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCC
+
@@@=DFFDFDAFHDHGIIAHEGHHIBGHH@CFGHGIIIIGIDHIHGHHGIBGHGHHHHEEEE=ACD=ACDDDCCCACCCDCDCCCDEDDDDCCCCDCDB
@84A
CTGGGGCCTTCACTAGTTTTTTACAGCCTGCCCTCGGGACTCCACAAATTGTTGTGGTTAGTGACACCATAGATGATGACCAGCCCTTTACTGAGGAGTCT
+
(7;15(0((.@>2))..)))(((.))...(((()((76('(9=3))((:3.8)(.-9=/)(6;=..((,4((((--,(:(,(((,(+5(3:(4::2((((+
@84B
TGGAGTTTCACCCAACAGATGCAAATACCATAATTACATGCGGTAAATCTCATATTTTCTTCTGGACCTGGAGCGGCAATTCACTAACAAGAAAACAGGG
+
@C@FFADEFHGHHGHIEHIGIGIJIIIIJIJGIIGGGHHIIIIGGGEIHHFIIIIIGIJJGGEHICHIHGJHEFFFDDDCCACCDCDCCCDCDDDCDDDD
@84C
TAATGACTCAGTGCTGGCAACATCAGCCTGAAGACAGGCCCAACTTTGCCATCATTTTGGAGAGGATTGAATACTGCACCCAGGACCCGGATGTAATCAAC
+
@@CFDFFDHHDDHIJEDHIGEHDDGEGIBHHGIGGIAECEHGIJJJJGHICFACGFIIIIHJGGGIHFHHGFFFFFFDCEDDBBD@BDBB=9<>@DC@CCD
@84D
GAAGAATTCCAACCCCGACGAGATTGAAATCGACTTTGAGACCCTGAAGCCGTCCACACTGCGTGAGCTGGAGCGCTATGTCACCTCCTGTTTGCGGA
+
C@CFFFFFHHHHGJIIJJJIJJJIJJJJJIJJJJJJJJJJJJJJJJJJJJJHHFFFEEDEEDDBDDDDDDDDDDDDDDDDEEEDDDDDDDDDDDDDDD
@84E
CTTTAAAGCAAGAGAAAGAACAAGTTTCATTGAGATGTAGAGAGCTAGAAATCATTATTAACCACAACAGGGCAGAAAATGTACAGTCATGTGATACTCA
+
CCCFDFDDDHHFHIJJJJIJJJJGHIIIJEIIHIEIHDGHGHHIJJIIJJJIJJJJJJJHIIJJJJIGGGJIGHHHFFFDBBDEDECCEDCACDEDDDDD
@84F
AAACCGAGTTGCAGTCCTGGAAAATCAAAATAAAACTCTAATAGAAGAGTTAAAAACTTTGAAGGATCTTTATTCCAATAAAAGTGTTTGATTCCTAAGA
+
CCCFFFFFFHHHHJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIIJJJJJJJJJJJJJJIIJJJIHHHHHHHHFFFFF;@CEEDEDDFFDDDDD
@84G
CCCATGCAACCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACAC
+
CCCFFFFF4DHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIIJJJIJHHHFFFFFFFEEEEEEDDDDDDDDCDDDDDDDDDDD
@84H
CGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJGIJJIJJJIHIJJJJJJJJJJJJJJJJJJJJJHHHHFFFFFEEDEEDDDDDDDDDDDD?BDDDDDDDDDACDDD
@84I
CACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGC
+
CCCFFFFFHHGHHIJJJIJJJJIJJJJJJJJJJJJJJIJJJIJJJJJJJJJJJJJJJJJJIJJIIJJJHHHFFFFFECEEDDBDDDCCDDDDDDDDDDDDD
@84J
TTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTG
+
CCCFFFFFHHHHHJJJJJJJJHIJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJHHHHFFFFFEEEDD?BDDDDDDDDD@CDDDDDDDEEDDDDDDDDD
@84K
GCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAG
+
@C@FFFFFFGDDHGGAHGIJJIIIJJIIJIJJFHIJJIIHJIIJGGCHIJIIIJIJCHEEHHGGFDCD8@DDDDCDDDDDDBDBDDDCDDDDACDDCC?
@84L
CTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTT
+
B@@FADFFHHGGHJIJGIJJJJJJJEHIJJJJJJJJJJJJJHJJJJJJJJJJJJJJIIJEIHHHCHHFFFFFFDDDDDDDDDDDDDDD@CCDDDDDD>@5?
@84M
CTGGGCCGCGTGGTGCACATCATCCAGTCACGGGAGCCCTCCCTGAAGAATTCCAACCCCGACGAGATTGAAATCGACTTTGAGACCCTGAAGCCGTCCAC
+
@@@DDBDFHHHHHEFGHIEGHIIJIIIFFIDGGIDGIIJIIJGEFHEEBFFFECECCCBDDBDDDDBDCDDDCCCBDBDDDDCBDCDDDCCCC>?@@@B?D
@84N
TCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAA
+
=?8=DDDA:D??8<E8A<<F<H<?EFEEIEED?9DF<?BDBD>?@BF3?DF8888=(==@EF<:BD<@;;;;>3;>BB<?999:55@>;;>ABBBBABB
@84O
CACAGTGCCTCTTTCTCACTTTGATGAGAGCATGGCCTACATGCCGGAAGGGGGCTGCTGCAACCCCCACCCCTACAACGAAGGCTACGTGTATTAACAC
+
@<@BDADD>AFHFEGIGGHBCEFHIIICHHGHBB?>CEGGECFEBFGBEHGHIG<8>B@DDEEECBCBBBBBB<B8>A>>B??<BCC<<(99?DCC@CC>
@84P
CTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGC
+
C@CFFFFFHFHHHIJJIJJJJJIIJIJJJJJJJIIJIJJIJJIIJJIJGIHIIIJJJIGIJJJIJJGIJHHHHHFFFFFEDEDDDDBDBDDDDDBBDCDD
@84Q
CATGTTCAGCGTAGAGTCGCTGGAGCGGGCGGAGCTGTGCGAGAGACTCCTCACTTGGATCCAGACATTTAATGTGGATGCACCATGCCAGACCGTGGA
+
???DDD,=D4@C:)C?4A@1@FD;3)0:DD/'96'=>>>(988?:(53393+90>>:>(:>9:>A>8:>>>>>A::>(4:<(4><>>A:>32880&+&2
@84R
AAGACCTTGGTGATTTAAGGCGGCAGGTTAAACTCTTAGAAGAGAAGAATACCATGTATATGCAGAATACTGTCAGTCTAGAGGAAGAGTTAAGAAAGGCC
+
@CCFFDDDHHHF?FHIIJEEHHJJIIJGIIIIIIIJIIIFEFHIHIGIJIJJHGEHAEHF@CFEDCECECEECCDCCCCCCCDBDDBBBA@@CCCDD@??B
@84S
CAGAAAAACAGGCCAGCTATGAACTATGATAAACTTAGCCGTTCACTCCGCTATTACTATGAGAAAGGAATTATGCAAAAGGTGGCTGGAGAGAGATATGT
+
CCCFFFFFHHHHHJIJIJIJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJIIJJJJJJIJIJIHHHHGFFFFFFEEDED;@BDDDDDDDDBBDDDEDC
@84T
CACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGT
+
CCCFFFFFHHHHHJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJIIJJJJJJJJJIIJJIHHGHHFFD;BDDDDDDDABDDDBDDDDDDDDDDDDDDDDDDC
@84U
CTCCTTCAGCATATTCTGAAGCAGAGGAAACCTCGGATTCTTTTTTCACCATTCTTCCACCCTGGAAACTCTATACACACACAGCCGGAGGTCATACTGC
+
@??ADDFAHBDDFIIIIIGIIEBE;B@@GGH@GEHGDGGHIIIEGHEBGGGIIGIIGGIIHIGGE>AEHHFBBD?C;A;<?BB=A?@??<B<AAACACDC
@84V
GGCACATCTGATGAGCAAATTTAATCATCCCAACATTCTGAAGCAGCTTGGAGTTTGTCTGCTGAATGAACCCCAATACATTATCCTGGAACTGATGGAGG
+
@@@FFFDD<DHHHIJJIDIIJJJJJIIJIIJGFGHJJGGIIIIGFFGFAFHHIBBFAHGGGIGGCHIJJJIIIJHGHDDFFFFFDD>CEBCDCC>C@@5?B
@84W
ATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCC
+
CCCFFFFFHHHHHJJIJJJJJIJJJJIJJJJJJJJJJJJJJIJJJJJIJJHHHHHFFFFFFEEEEEDDDDDDDDDDDDDDDDDDDDDDDEDDDDDDDDDD
@84X
GATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCT
+
CC@FFFFFHHHHHHIJJJJJJJJJIJJJJJJJJFHIJJJJJJJJJJJJJJJIJJJJJJJJIJJJJJIJJHHHHFFFFFFEEEEDDDDDDDDDDDDDDEDDD
@84Y
CAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGG
+
@@@DDBDDD?BHAEGIFHGI?CE>FFFGCGHBFEEGGGG@?FHCGECH@ADFFF3==@AGH6AC6?;?DEEEEDEDCABB???BBBBBBB?@+4+>CCAA?
@84Z
GTGGATGGCACCAGAAGTCATCAGAATGCAAGATAAAAATCCATACAGCTTTCAGTCAGATGTATATGCATTTGGAATTGTTCTGTATGAATTGATGACTG
+
C@CFFFFFHHHHHJJJJHIJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJIJJJJJJIJJIJJIJJIJJJJJJIHHHHHHGFFFFFFFDDEEEEED
@850
CAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTT
+
@C@FDADDHFDHBF@H@CADEHCBDH9CGHIGC?D;CDHIIIEGFFGIGE@FHIB@=CEH>CG?E>;AC>?;?B;6;;6;>@CCDC?;:9?C3>C?BBAC
@851
AGAGATTGAAAAGCAAAGGAACACTTTTTCATTTGCTGAAAAAAAAACTTTGAAGTTAACTATCAAGAGTTACAAGAGGAGTATGCTTGCCTTCTCAAAGT
+
@C@FFFFFHHHGHJJJJJIJJGIIJJJJJGGIIIIIGJJJJJJJJJGGIJIEHIFHEHFFDDEDFED@BEEECDCC?BD??9>@DDDDCDCDDACCEDDD>
@852
GAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACC
+
CCCFFFFFHHHHHJJJIIIJJJJIIIJIJJIJJIJJJJJJJJJJJJJJGIJJHHGFFFFFDCEEEEEDDDBDDDDDDDDDDDDDDDDDCDDDDEDDDDDD
@853
CCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTAT
+
CCCFFFFFHHHHHJJJJJJIJJJIJJIIJIJJJJIIIJJJJJJJJJJJIJJHHHFFFFFEEECEDDDEDDDDDDDDDDDDDDDDDDEDDDDDDDDDDDDDD
@854
CTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGG
+
@@@FBDDDFHHHGIHHI@DCGGIIIIIIIIHGHIIIIIIIGIIIHGHIIIHIFB@FHGHIIIIFGIGGIFHHGHGFFFFFED@AECDCDCDC@?BCCCDDD
@855
GTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACC
+
@CCABDDEDDHHHIJJJIJJGJJIGIGGHBFHEEGGGGFHHIIIGEGGIJJIIEIJGIIJIIIJJFHGHHFBEEFFFEDCEEEDCDCCDBDD@ACBDCBB@
@856
CTCCAGACTCTTTTTGACCAATATTGTTTCCTCTTTCAGAAGTGCCTAGCTGCCACTCCATTTATATGAGGCAAGAAGGCTTCCTGGCTCATCCCAGC
+
C@@FFFADFH>FDGGEBHIEHEGIAIAHGGCGIIIGIJIEHG4BFHHCGGECGEEHHIGHGIIGFGDGHIHHEHIHDFFFDEFCEECC;@CCCDDDCD
@857
GTCGGAGGAAGAGGACAAGTGCAAGCCTATGTCCTATGAGGAGAAGCGGCAGCTCAGCTTGGACATCAACAAGCTCCCCGGCGAGAAGCTGGGCCGCGTGG
+
BBCFFFFFHHHHGJJJJJJIJJJJJJJJJJJIJJJJJJJJJJIJJJIIJJJHHGHHFFFFFDDEEEDDDDDDDDDDDDDDDDDDDDDDDDDDDBDDDDBDD
@858
GGCCTCTAAACTTAGCCTCTCACCAAGGGAGCATCCCCTCAGTCCTCACCATGCCTCAGGAGGTCAGGGCAGCCAGAGAGCATCCCACCTGCTCCCTGCTG
+
888:DDDAD4C2A44CC:+++3C3FEEED)?CDDABDD;DD>?B<4*?((884=C:=C7@@@8;ACD@((;/;>AA2;>;>3,:595<2592(+4<<><AA
@859
GCCCTTTAAATTCAGCTATGGAGAAAAGTGCCTGTACAATGTCAGTGCCTATGATCAGAAGCCACAAGTGGGAATGAGGCCCTCCAACCCCCCCACACCGT
+
C@CFFFFFHGHGHJIJJIJIJJJJJJJJHIJIIJHIJJJJJJJIJHHIJJJJJJIJJJJJJJJJIJJJHHJIJJFIIHHHHFFFFDECDDDDDDDDDDD5?
@85A
CTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCT
+
@;;D?DD<:AF;DGI@?AEEGI3A<FCGIIIBDG@@8D@FIIIEBBBDABC@CFFIEEFFF;@)=@;A7?EFDB<?BBBADDE@>3:>>BBB>95>A44>@
@85B
CAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTG
+
CCCFFFFFGDHHHJGHIIIHIGIJJIHIGHHIIIJIIDGGHI@FEFHIJJJGFHG=EFFFFECEECEC>C@C@CC>CCCEBCCCCDD>CDCDCBD>CCCCC
@85C
TATACTTACTATTCTAAACCCTAGTAGGCTCCCTTCCCCTACTCATCGCAATAATTTACAATAACAACAAAGTAGGGTAAATAAAAATTCTACTAATCACT
+
(0;958=)224;=8:<)29)(2;<@=?<81((:=<1>3):6(9))0))7==/9>?;=?)9)...)/<(663)).).(.99).(..(.3;-7(-7(((((,,
@85D
GTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACA
+
@@@DFFFFHHHHHEFAGGIJJJJJJIJIJJIJJIJJJJJJJIJJJJJIIJIIJJJJ@FHGHIJJJJJGHFHEFFFFDECDDDDDBDDDDDCACDDDDDD
@85E
CTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACT
+
@@?DDDDDABA?ACAG?AF?CCHFEFC@CEB?F?GB;DBGBFHGHHDHGIGHIG@D=66AEEECDCCCC>B>;C@?ACA?CB,9ACCCCCCEDCC@@@AAA
@85F
GTTATTCCCATGTCCTGTATAACCAATGGAAGTGGTGCAAACAGAAAACCAAGTCATACCAGTGCTGTCTCAATTGCAGGAAAAGAAACTCTTTCATCTGC
+
@@@FFFFFFFFDDC@GE?IDIHH3CGEEHFEGFBGHC9@DB@D@GHIGDDF?BB?FGFBFHCHEE@CFHIEECHC=E;?CHFFC;AAE>;CCCC;@@;ACC
@85G
AGAGGACAAGTGCAAGCCTATGTCCTATGAGGAGAAGCGGCAGCTCAGCTTGGACATCAACAAGCTCCCCGGCGAGAAGCTGGGCCGCGTGGTGCACATC
+
CCCFFFFFHGHHHJJJJJJJJJIIJJJJJJJJIJJIJJJJJJIJIJJJIIJJJJJJJJHHHHHFFDFEDDDDDDBDDBDDDDDDDDD@B@BD8?ACCCDD
@85H
GAAGAAGGGGGTGCAGTGGAATTCTCCTTAAAAAACAGCATGTTCTAGAAAAGCCATGCTTTGGAGGTGCTGTAGGCTTGCAGCCAATTTACTGGAGCAGG
+
@@CFFFFFHGH@FHIJGIJJJJJJJJJJJJJJJJJJJJJJIJIJJJJJJJHHHFHFFFFFECEECED?ACDDACCACDDDDDDDDDDDDDDEDDDDDDDDD
@85I
GAAGAAAGAATATGTGAAATGCCTGGAAAACCGAGTTGCAGTCCTGGAAAATCAAAATAAAACTCTAATAGAAGAGTTAAAAACTTTGAAGGATCTTTATT
+
8=8:ADDD?F?>?FAF>G9E<HCBFBCF?CB1?DEGA@9B?DD09?BB*9B@)=C4BB;CCF@))=D@EA>.?C=(.7@CDECBCCCA>A;>(-:3:@>CC
@85J
CTTCTCCCCAGCCCTCTTCACAACCTCTCCAAATACACAGACAAACTCCAGAAAGCAAGAATGCTACTCCCACCAAAAGCATAAAACGACCATCACCAGCT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJIHHHHHFFFDDDEEDDDDDDDDDDDDDDDDDDDDD
@85K
AAGAAAGTAAGCAAGAACAGTTGATTTTGGATCACTTACCATCTGTAACAAAGGAATCATCACTTAGAGCAACGCAACCAAGTGAAAATGATAAACTTC
+
++1+?7<2?><A++2+2<+3,3<A3A,@+)<*@11111?*11?==0?70*:A;A2=3//)/8..8A.877=)('-5='(;@@(----5=;9(59559>9
@85L
ATTGAATCCCTTTTTGATCATATCTACACCACGCAAAGTGATGTATGGTCTTTTGGTGTCCTGCTGTGGGAGATCGTGACCCTAGGGGGAAACCCCTATCC
+
CCCFFFFFHHHHHJJJIJJIJIJJJJIJJJGIJJIIIJGGGIIGIJIGIJJJJJIIFGIJJJJJJJIJHHFFFFFDCEEDDDDDDDDDDDDDDDDDDDDDD
@85M
GTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCC
+
@CCFDFFFHGHGHJIJJJJJJJJIJIIJJIJJDHIIJJIGHHIGIIGIGHHGGIJGIICEHIJJCEHHHFFDDDCDDDDCDDDEFDFDBBDBBBB<ABDDD
@85N
GGAAAAGAAAAAAGAAAAGCACAAAAGGAAAGAGGAAGTGGAAGAGAATAAAAAAAGCAAAGCCAAGGAACCTCCTCCTAAAAAGACGAAGAAAAATAAT
+
@@?DDDDFGHDFHIIIIEC@DHGGGIGGGHIEFGECFGHIIGHHEGIGCFGEGGH>BDFCEAC6?CB?ACBBCCB?CACCCCCCB?<9@B8<CCCBBCC@
@85O
TCAACATGTTGTCATGACAGCCATTCAAGAGCTGATGAGTAAAGAATCTCCTGTCTCTGCTGGAAATGATGCCTATGTTGACCTTGATCGTCAGCTGA
+
-3((-9.)2618=)@>>?841:=?<<==89(4)1)9;>?>=<83)<><.<>1;.:1=<<:61.=3))))/)).6;8>))=8:>983);=9.(69:;3;
@85P
TACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCC
+
CCCFFFFFGHHHHJJJJJJJIJJJJJIJJIJJFHIJJJJJJJJJIIJJJJJJEGIJJJJJGJJJJJHHHFFFFFFEDEEEDCDDDCDDDDDDDDDDDDDDD
@85Q
CACACTGCAGATTATTGGACTTGGCACTTTTGAGCGTGGAGTAGGATGCCTGGATTTTTCAAAAGCAGATTCAGGTGTTCATTTATGTGTTATTGATGACT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJGHIGHDHIJIJJJJJJIIJJJJJJJJJJJJJHHGHHHFF?CEDEEEEEEEDBDCCDDDDDEDEDD
@85R
ACTCGATCCGCCTGCCTGCGCACCTGCGCTTGCAGCCAATTTACTGGAGCAGGGATGACGTAGCCCAGTGGCTCAAGTGGGCTGAAAATGAGTTTTCTTT
+
?@?BD?DDAFFDD=GE:2381:?:1CD0?6?@@F?F8=BFA<==C>A=CCC>;A(?=B@;;=A(;>=?55(<<@@B>,(5??9>BA::A@:>AD>ABBBB
@85S
TGAAGAATTGAGCTTTTCAAGGGAACAGATTCAGAGAGCTAGACAGACAATAGCTGAACAAGAAAGTAAACTTAATGAAGCACATAAGTCCCTTAGTAC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJIIJJJJJJJJIJJJIJJJJJIJJJJJIJJJ@EHIJJJHHHHHHFFFFFCEEECFEDDDDDCDE
@85T
CTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGAC
+
CCCFFFFFHGGFHJJJJJJJJJIJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJHHHHHFFFFEEDDDDDDDDDDDCDDEEEEEDDD
@85U
AGCAGAACAGAAGGCTGTATGTTTGAAAAGGGCCCCAGGCAGTTTTATGATGACACCTGTGTTGTCCCAGAAAAATTCGATGGAGACATCAAACAAGAGCC
+
@@CFDD??FDHH>DHBDFFBDCFHE<EEH@;;8CGEHIGIII?DFHIIGGHB<DG>@@C@DHGHGHHGFHFEBB?AC;5(;>>5;??<@C:@>3<B<A2<?
@85V
CAGCTTGAAGACCTTGTTGAAGAATTGAGCTTTTCAAGGGAACAGATTCAGAGAGCTAGACAGACAATAGCTGAACAAGAAAGTAAACTTAATGAAGCAC
+
CCCFFFFFHHHHHIJJJJJGJIJIJJJIIIJJIJJJJIIJIIIIIJJJJJIIJGIJJJIIIJJJJJJIIJJJHHHFHHFFFFD>@EECEDDDECDDDDDD
@85W
CTATGAACTATGATAAACTTAGCCGTTCACTCCGCTATTACTATGAGAAAGGAATTATGCAAAAGGCGGCTGGAGAGAGATATGTCTACAAGTTTGTGTGT
+
???D7D:?CB:2,<C?EEI<E:<<FCCB9+2?:):)??9DD>**09*00?9(9BCCC4=@>CC7.((-','3/=((,<88>:4(4>>(>>>++:44<9<<?
@85X
CTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAA
+
CCCFFFFFHHHGGGGHIJHHIJJJJJIJJJJJJIJIJJJJIGJIJJJJJJJGIJJJIJIJIIJHHFFCEECEDDDDDDDBDDDBACDDDEDDDCDDDCDD
@85Y
GTTCTGATAATGAGTGTCTAGGCAGATCTCTGAGGGGACCTGAAATCTGATGCAGCTCTCCTTTGTTCTAGGTTATACTACTCCAACTGCCCCCCAGGCAT
+
@@@FFFDDFDCDH@EFCFHHIIEHIIIIIGHGGHIGEDFGFGIIGFCHIGIGI@CGEHEGIIII>EEGIHGEAC>AEC@CFDCAAC@ACCCCBBBC???BC
@85Z
GTGCACCATAACCCTCCTACCATTGAACTGTTGCACCGCTCCAGGTCACCTATCACGACAAATCACCGGCCTTCTCCTGACCCCGAGCAGCGGCCCCTCCG
+
::?1;3AD?C:<+AE3A:CF+3<+<+<A<9:??@*C@DDDA0BAD**9)=B@8=@CDDA4A..7).7?@??>A(::5:>:>:9>>&5&538005900+92&
@860
CCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCC
+
@@@DDDDDHHHHFGG?EGHIDDHDEGHHGIIGFHB?DFEIIIFIGFHIGDHHIIIIIDEIHHHCHEEBBDCCCBCBBCC>CDCCCCBBBB@BBBCCCCCCC
@861
GGAAAGGACTGTAGAGCTAATGTTTACCTTCTTCCGACCGGGGAAATCGTTTATTTCATTGCATCAGTAGAAGTACTATTTAATTATGAGGAGAGAACTC
+
<<?DD3=?2CCDDBE@E<C+AAAFFCFFCBEF@EEEEDDDDDDIDCE);.?C;A73;;776>>@AA>>AA(;>;>A>AD>;;>A>A>55:9(<8<<AAA3
@862
TTTGAACAGTTGTCTGGATCCATTTTGTGGATGGCACCAGAAGTCATCAGAATGCAAGATAAAAATCCATACAGCTTTCAGTCAGATGTATATGCATTTGG
+
@@CFDDFBHB?FHHGHGIGGIJEHIGHEFHJBDHEGIJJJJJE?DIGHIGGHHEIJGGGHHIIGGEDHG@D>EGGCCEEHC???C@CEA@@DCFCDECADD
@863
CCTCCATGCCTGTCACTTCCTCCAGCTTCTTTGGAGCCGCATCACAATACTGGACCTCCCCCACGGGGGGAATCTACCCCAACCCCAACGTCCCCCGCCAT
+
CCCFFFFDGDFDHGIIHIJJIGHIHIGIIIJJJJJJJIJJJIJJJJJJJJGIJJJJIGIJJJHHFBCCDDDDDDDDDDBDDDDDDDDDDDBDDDDDBDDDD
@864
TTTTGAGCGTGGAGCAGGATCCCTGGATTTTTCAAAAGCTGATTCTGGTGTTCATTTATGTGTTATTGATGACTTCAATGAGCATATGCTTACTGTATGGG
+
(-((88-=(<9/-3)2.(:8)2)1).())1.)0.3;)9()))0:=)9<;)661363.;>)))))).)<;>8=>;))86=6=;.((.:((-6(73:;70(,(
@865
ACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGC
+
<@@DDDDDHH?DB?DGFHG@FBD9CFGDCF@HIGD?CF=DDEECHIIIEGHIIIEEGDHIIIG;C9CEEECHDBBECCCB?BCCCCCCCCC:@C@ACABB
@866
TACGTTCTTCTGATGAAATATCATCCTGCTACTGACGGGTATCAACATACTAGTGAGAGCCCTATACTGCCTCTACGTATTTAAGAGGACACAATGGTGGT
+
1=++4++=2,,<CD2,2+<<C333,3A+<2<+++**1))))****)*099B****))/82.5))7)77.))))))),6.7?B@(..(,((,(,(,(((,('
@867
CCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGT
+
CCCFFFFFHHHHGJJJJJJJGHIIJJJJJJJJJIIJJJJJJIJJJJJJJJJJHHHFHHFFFFFFEEEEEDDDDCCDDDDDDBDDDDDDDDDCCDDDDDBDC
@868
CCAAAAGTTACCAAAACTGCAGACAAGCATAAAGATGTCATCATCAACCAAGAAGGAGAATATATTAAAATGTTTATGCGCGGTCGGCCAATTACCATGTT
+
@@@DBDEFFHHHGIIGI>ICGGGEGGIIIGEHIIE>FGCHIGGGBBFFGHGGFGIGGGIIIGIHHGFGHGDGHHH>AEF>DA@BBB;?BBCCCC>@@CCDE
@869
TATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTAC
+
CCCFFFFFHHHHHIJJJIGGJHIIJJJIJJJCFIJJJJJGIJIJJJJJJJIIIJIJJJIGIJJJIHIJHHGHHFFFFFEEEDDDDDDDDDCDDDEEDDDDD
@86A
GATTTCGTGGTGATGGAGGATCAACCACAGGTTTGTCTGCTACCCCCCCTGCCTCATTACCTGGCTCACTAACTAACGTGAAAGCCTTACAGAAATCTCC
+
B?BFFDFDHGHHFJJJJJIJJIIJJJJJJHGDGHIIIJJIJIJJJIIIHHHHFFFFFEEEDEDDDDDDDDDDDDDDDDCDDDDDDDDDDDDDDDDDDDDD
@86B
GGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTAC
+
CCCFFFFFHHHHGJJJJHJJJJJJJJIJJJJJJJJIJJJJJJJFJJJJJJJJJJJHHHHHFFFFDDBBDDDDDDDCD@CDDDDDDDDDDDDDDDDDDDDDC
@86C
TGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGG
+
BCCFFFFFHHHHHJJIJIJJJJJJIJJJJJJJJJJJJIJJJJJJJJJJFGIJIIHHHHFFFDDEDEDDDCDDDDDDCDDDD@CDDEDDDDEDCDDDDDDBD
@86D
AGCAGCTCAAAGCCGTGCACGAGCAGCTTGCAGCCCTCTCTCAGCCCCAGCAGAACAAACCAAAGAAAAAGGAGAAAGACAAGAAGGAAAAGAAAAAAGA
+
@CCFFFFFHHHHHJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJIJIJIIIJJIJGHHHFFFFDEEEEDDDDABDDDDDCDDBDDDDBDDDCDDDDDDDD
@86E
CGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTAT
+
C@@FFFFFHHHHHJJJJJJJJJJJJJJJJJJIIJJJJJJJJJJJJJIIIJJJJIJADFFFFFDDDDDDDDDDDDDDDDDDDDDDDDDD@CCDEDCDCCCDC
@86F
GGGAAATATGAAAAGCCAAAATTTGTGCAGTGTTTAGCATTCTTGGGGAATGGAGATGTTCTTACTGGAGACTCAGGGGGAGTCATACTTATATGGAGCA
+
1+14=+=ABDBBAAE;;C:BE9FEE,AE@F<?EEEFAEC<D*CC>D0))8BDCE9?)88==@A>>.=)=2@()773A(,3;=(::((((,55:>4:(<((
@86G
CAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGT
+
CC@FFFFFHHHHHJHIJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIHHHHHFFADEEDDDDDDDCCDDDDDDDEEDDDDDDDDDDDDDDDE
@86H
TTGAGCTGCTGGCCCGCTCATTGCCAAAAATTCACCGCAGTGCATCAGAACCCTCCTTGAATCGGGCTGGTTTCCAAACAGAGGATTTTAGTCTATATGCT
+
@@@BBDFFHGHGHFGIIIJJIHI@GHIEGJIJJJJIIJEGFHIIJFIIJII;;DGHHFHECEEFFDDBDD?CDDDEDD=??CCB8?CCD@C>@CCDCDDCE
@86I
AACAGGAATTAGAGTATAAAAGTAAACTTAAAGCACTTAATGAAGAGCTTCATTTGCAAAGAATAAATCCAACTACAGTGAAAATGAAAAGTTCTGTCTTT
+
?;8D?BDDHH:A<4ACBFFFEGC?ACHFAFFH>H@;CFEHD@FH90BGHHG>??F:F<B49*B4BF8CB)..8C7.7=DEH3AE3=;7;?;AC>C>>@A>>
@86J
AGAGAATAAAAAAAGCAAAGCCAAGGAACCTCCTCCTAAAAAGACGAAGAAAAATAATAGCAGCAACAGCAATGTGAGCAAGAAGGAGCCAGCGCCCATG
+
@C@FFFFFHHHHHJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHHHFFFFFFFECEEDDDBDDDDCDEDCDDDDDDDDDDDCDDDDDDDDD
@86K
CTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTAT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJIJJJJJIJJJIJJJJJJJJJJJJJJJJJJJJJJJJJHHHHHHFFFFDEDEEDDDDDDDDDDDDDDDDDDD
@86L
CAAGAACAGCCCTTTAAATTCAGCTATGGAGAAAAGTGCCTGTACAATGTCAGTGCCTATGATCAGAAGCCACAAGTGGGAATGAGGCCCTCCAACCCCCC
+
@@@FFFFDFHHHHJJIDIJIIIHCGHGIIHGGJIG>FEHIJGIJJJJDGIJGHHGIGGHGGGGEGGIJIIIJJJGG=EEHFFFFFFC@A@BABCCCDBBDD
@86M
TCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGC
+
CCCFFFFFHHHHGJJJJJJJJJJJIIJJJJJJJJJJJJJJJJJJJJJJJJJJHHHHHDEFFFFEEEEEEEDDDDDDD@CDDDDDDDDDDDDDDDDDDDDDD
@86N
CAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTAC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJHHIJJJJJJJJJJJJJJJJJFHIJJJJJJJJJJJJJJJJJJHHHHHFFFFFEECEEEDDDDDDDDDDDDDDDDDD
@86O
CAATGAGCTGTGGTCTCAGAAGGTCTTTGTCTCCAAGGTGGAGGCTGTCATTCACCCTCAATTTCTGGCAGATCTGCTGTCCCCAGAAAAACAGAG
+
==<AAA@:ABAB+?C>BBB7?>CBBB<@>7ACCB<;AAABA==AABB59=AB??BBB==>3==AB>ABBAAA>A;AA37;>@@@>;;>?====9?:
@86P
TGCTGTCTCAATTGCAGGAAAAGAAACTCTTTCATCTGCTGCTAAAAGTGGTACAGAAAAAAAGAAAGAAAAACCACAAGGACAGAGAGAAAAAAAAGAGG
+
@@?DFFFEFADFDHGIGGGGCGGGBCCHBHHIEDGDHIIIICHGGIGGDHHGGHIE:FGHIIG@EEHHFBBC@<AAC@BDDDBDB??CB@CCCDDDDD@C?
@86Q
GTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCC
+
@@CFFFBEHHHHFHIGGIDGIGHIJJIJJJIIIIJHIGGIIIFHGGIJFFEHFHEEFDFFFECDDCDDDDDBBBDDBBDDBDDDD:@CEDDCCDCDDDD
@86R
GATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCC
+
@CCF????BFDHDHGGGEGIGGHGIIIIIIGHICDEEHGIIGEFGGIIDHGIIIIIGIIHHA=ACECCDDF??DECEDE>CCC?>ACC>???@?A?B@CCB
@86S
TTCCCACTGGTTATACTACTCCAATTGCCCCGCAGGCATACAGCCAGCCTGTCCAGGGGAATGGCACTGGAGGTTATGATACCACCACTGCTACAGTCACC
+
(0(:9?1(639:>8?1;@=>11).)361))((1(094>?1)9)3=(<((.6).;=);'5'5977(((96((7(,20((73((38(-(26(((+3((4((4(
@86T
CTGATGGACAGCAGATACTTGTGCCCAGCAATCAGGTGGTCGTACAAACTGCATCAGGAGATATGCAAACATATCAGATCCGAACTACACCTTCAGCTACT
+
@@@FBBBDDHHGGIIIIIIEEEGBHIGGIGGBE<GCD@A?F?@FGGIA?FHGGHIIIGE=CGEEHEHE??AEFEEFFFBCCD159=;A>?A:5?>@CC@:C
@86U
CCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACAC
+
?;?B=A+BADB8CDBAEEEEFII93<EEFEEEEEIEIDD@ED3D;BDDEECDEEDE:=C=C9@AIDDD@DAD:;@AAA>AA3(--5;>>:>55>><5>59(
@86V
TGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTT
+
?@7BDDDD?FFDHII>GGHIGDIEHGCEEFGFHGCHDD<BBBBDDG9?FAGHGHIIGGIICDGIGG;ACHE@BEE:BFEBCADB??;;=<C@CCCCCC>AC
@86W
CGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCG
+
CCCFFFDDHHHHHGHIGGHHFGGGHHIGHIJGHJGG@CGIHGIIJGHHFFFFECCCCECCCDCCDDDBDDCDDDDDDDDDDBBBDDDCDD:CCDDDDDDDB
@86X
CACGTGAATATGGCATTCTCTCAGTCCAACCCTCCTTCGGAGTTGCACAAGGTCCACGGATCCAGAAACAAGCCCACCAGCTTGTGGAACCCAACGTACGG
+
@CCFDDBDHBDHHGBHGHJGEGHIIIJDHHEFIJJGFGGIGIFEHIJJJHGEBFCGIIIIJHHHHHFFFFFEDDDDDDBBBDDDDDDDDDDDDDDDABDBD
@86Y
AGGAAACCTCAAGCTGAGAAAGTTGATGTGATTGCCGGCTCCTCCAAGATGAAGGGCTTCTCGTCCTCAGAGTCGGAGAGCTCCAGTGAGTCCAGCTCCTC
+
CCCFFFFFGGFHHGGIGIJJJJGHHGHIEHGIJJJJJJJGJJJJJIJJJJGIJJJIJJIIHIGHHHFFFFFEACCDDD;?ACCDCC@CDCCCCCDDDDDDD
@86Z
ATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGCCACTCACCCTGCTTATCCAGCC
+
111<@AA;=722?CC>@7?<A<=+@<CA=A>@BAB=1?AABA==ABAAABABABB<)..8>87>A7=B7AA.7)7).)).;>;>5(5;=9=???5;=>9=;
@870
AAACAGTTAATGGGGACAGTCGAAGAACTTCAGAAGAGAAATCATAAAGACAGCCAGTTCGAAACTGATATAGTACAACGAATGGAACAAGAAACACAA
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJHIJJJJJHHHHHHHFFFFFFFEDDDDDDDDDDDDDDDDDDDD
@871
GGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCC
+
@@@DDD?BDHHD?DGIB@GHGGGFCHCGCCGBHGHI8FHDGHC>@=F;CFGGGGF>C;@:BDC@6;6;AA3=@C@ACA>C@CCC@B<>09?@C:@B<ABBB
@872
TACAGTGGAAGATTTGAAAGCTGAGATTGTTTCTGCATCTGAATCCAGAAAGGAACTAGAATTAAAACATGAAGCAGAAGTTACAAATTACAAGATAAAAC
+
CCCFFFFFHHGHHJJJJJJJJJJJJJJJJJJIJJIJJJJIIJJJJJJJJJJJJJJIJJIIJIIJJJJJIJJIIIJJJHHHHHHFFFFFFEDEECCDDDDDD
@873
ATTCTGAACAAGGAGCACAAGACAGTCCGACTCATCTAGAGATGATGGAAAGTGAGTTGGCTGGGAAGCAGCATGAGATTGAAGAGCTAAACAGAGAGCTG
+
CCCFFFFFHHHHGJJJJJJJJJJJJIIJJJJJJJJJJIJIJJJJIJJJIJIJBGGIIIJIIJJJJGHHHFFFFFEEEEEEDDDDDDDDDDDCDDDDDDDDD
@874
CTCGAGTGATGATTGGGAGATTCCTGATGGGCAGATTACAGTGGGACAAAGAATTGGATCTGGATCATTTGGAACAGTCTACAAGGGAAAGTGGCATGGTG
+
CCCFFFDFHHHHHJJJJJIIJJJJJJJJJJJJJJJJJJJJJHIJIIJJJJJJJJJJJJJJJJJJJJJJJJGHHHHFFFFFFEEEEDDDDDDACDDDDDD:A
@875
AGAAATACAGGAAAAGGAGACAATCATTGAAGAATTAAACACAAAAATAATAGAAGAAGAAAAGAAAACTCTTGAGCTAAAGGATAAATTAACAACTGCTG
+
CCBFFFFFHHHHHJJJJJJIIJJJJIIJJIIJJJIIJIJJJJJJJJJJIJJJJJIJIIJJJJJJJJIJJHHHHHHFFFFFFEDEEEEDEEDDDDDDDDDDD
@876
AGGGTAGGCGACATCGAAACGATCAGAATAATACCTGCACACCCCCTCCGCCCAGATGCCCCGGATGGACAAACTTCCCTCGCCCCCCCCCCACCTCTCAC
+
00(2(2-()((((()()251-(1(1))).))0).)))().).(''-3-(-'(9'(.(((((('3'''(++(++(++:4++()&)5)05)5&&5006((+((
@877
GTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGC
+
??@DDDDBB?FF?9E:CFABDH@EFGHIEGFDHGEHIBDDFBFHHHIGGIIIIFBECHAGGHHA>?@BEECACCCC;;A@CCCDC3>:ABBBCCC:<A1<B
@878
ACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAAC
+
CCCFFFFFHHHHHJJHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJHHFFFFFEEEEEEDDDDDDDDDDDDDDDDDDDDDD
@879
GCTGTATGTTTGAAAAGGGCCCCAGGCAGTTTTATGATGACACCTGTGTTGTCCCAGAAAAATTCGATGGAGACATCAAACAAGAGCCAGGAATGTATCGG
+
=?;=4=2B==DD:<C<22AECEECE;8?CDC?B<B99D9:?DB80?*0B/8BBBCBEACAC;@C75?=AA>;75;;@AA;3>?>=,;9A?9<<A:(;(:2>
@87A
ATTTTTATGGTGGGACGAGGATACCTGTCTCCAGATCTCAGTAAGGTACGGAGTAACTGTCCAAAAGCCATGAAGAGATTAATGGCAGAGTGCCTCAAAA
+
@CCFFFFFGFFHGIJJIGIIIJIJGEGHHGHIJIHIGGFHIIIJJJFGHIJGH@GHHIEEHHHHHBCBDCAECECCBCCDDDECDBCB@B:ACDDDDDDD
@87B
GTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACT
+
?@<DDDDDF?HHFHHGIII@EAF?CHHIEHBGGEHIBEHIIBHGBHIG3BFGCFHGGHIIEE;;C>CHC>AEEEEECCC?CCCCEECCCCCCCCB?BB<99
@87C
TTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTG
+
CCCFFFFFHHHHHJJJJJJJJIJIJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJHHHHFFFFFEEEDD>BDDDDDDDDD>ACDDDDDDEEDDCDDDDDD
@87D
GCAAGCCCCCTCCCACGTATGAGTCGGAGGAAGAGGACAAGTGCAAGCCTATGTCCTATGAGGAGAAGCGGCAGCTCAGCTTGGACATCAACAAGCTCCCC
+
CCCFFFFFHHHHHEIJJFHIICHEGIJFGGGHGHIJJJGJIGHIIJGIGIJHHHHHHHEFFEEECDECDDDBDDDCCACCDCDDCACCDDDCDDCDDDCDD
@87E
AACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJGHIJJJJJJJJJJJJJJJJJDFHJIJJJJJJJJJJJJHHHHHFFFFEEEEEEEDDDDDDDDDDDDDDDDDDD
@87F
GTGGAACTGGAAAGTGAAATTTCAACCACAGCAGATGACTGCAGTTCAGAGGTAAATGGTTGCAGTTTTGTGATGAGAACAGGAAAGCCTACAAATTTATT
+
@??BDDFFFBDHHGCC?EHHIIEDHHIIGHIIHGCDFGHIGICGGHEHIIIIBGHGHGICHHIIIFHIICCHCGEAEEEHEFEEEEAC@AC?CDDACCACC
@87G
TGGAGCCTTTGGAGAAGTGTATGAAGGAACAGCAGTGGACATCTTAGGAGTTGGAAGTGGAGAAATCAAAGTAGCAGTAAAGACTTTGAAGAAGGGTTCC
+
<?@D;DD?DFHDBB9EDEFEHGGGCE;EHGE?:9?:19?F@EEHE@DFDD)9?<BDF)8BCDHGFECE@>C)7)7???CHFCDFFDCACCACC>AB(9<@
@87H
CCAATTTACTGGAGCAGGGATGACGTAGCCCAGTGGCTCAAGTGGGCTGAAAATGAGTTTTCTTTAAGGCCAATTGACAGCAACACGTTTGAAATGAATGG
+
C@@FFDDFBHHHHJIGBEEHIEHGIEHAGFIJA?FDADGHDFGHCHGIBGFIGFIEIGCCD>GHHG>CHHHFFCD@>>CEDEDDDDDDDDDDDD@CCCEDD
@87I
GGGAGACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCACCAGGGCTACAGTGCTT
+
?@7?DDDDHAHD?A?FECB@G9??CF@8D8/B;/=8B@GGEG;;>EEHE?DB<C?>AC::5>A>;5>ACC>A?B?>AA?CA0<3<>18?>?<?C3>:@3>@
@87J
ATTTGGGCAACGAGACCGATCCTCATCAGCTCCCAATGTGCATATAAACACAATAGAACCTGTCAATATTGATGACTTGATTAGAGACCAAGGATTTCGTG
+
@@CDDFFFGHHGGHIIJJJJJJJJJJIJHIIJJIJJIIFHIIJIGHIJHJHIJFEHHHHFFFFFDEEEEFDEEDDDDDDDDDEDDDDDDCDDDBDDDDDDD
@87K
CCACACTGGGGTCTTCCAAAGAAACCCTTCCACCCACATGCCAAGGCAATCTCCTTATCATGGGGACTGAGGATGCCTCCTCCTTGCCTGAAGCCAGTCA
+
CCCFFFDFHGG@FHJIJIIGJIIIJJIIGIIGIIJGHIJIJJJIJJJIGJIGJJGIGHIJJJJHHHFFFFFDDCEEDDDDCDDCDDDDCCCDCDDDDDDD
@87L
GTGATGATGGTGCTTCTTCTGCTCCCTCCCGGGGTGCCCCTTCTTTTTTGACTTCGGAGCCATCTCTGTTTCGGAGTCTTCGCTGTCAGAGGAGCTGGACT
+
@B@FFFFFHHFHHJJJJJJJJJJJJJJJJJJJJIGHJIJJJJJJJJJJJHHHHHHFFFDDDDDDDDEDDDDDDDDDBDDEDDDDDDDDDDDDBDDDDDDDD
@87M
AGAATGGCTGAATCACAAGAAGCTGAATTAGAGAGGCTGAGAACACAGCTTCTATTTAGACACGAAGAAGAGCTTTCCAAACTGAAGGAAGATTTAGAAAT
+
===7?<AACAAACB4A4<+3+3+3?CB9771:7@:5110=)0:**9==A>=<?>7>)>.))8A6/4-'=).6)>;>>@;;;=?=;;;;29:=??99599;=
@87N
CTGGACAGTTACCTTATTCAAACATCAACAACAGGGACCAGATAATTTTTATGGTGGGACGAGGATACCTGTCTCCAGATCTCAGTAAGGTACGGAGTAAC
+
C@@FFFFFHHHHHJJJIJJIJJGIIJJJJJGIIEGGIIIIJJIIIJIJJIIJFIIIIGGHIIHGDDCDFE>>>CCDDCCC>CCDD@@CCC:ACDDBB8>C:
@87O
CTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTT
+
;;(-8)=>==9<).@3;:@@>?<>@..=9:99:9;936;;3.<=>?<7673.<5;=5599>>99)..36=893==<<<8;55<<<<9<:6:2(6:8<<68:
@87P
CAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCC
+
CCCFFFFDHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJHIJJJJJJJJJJJJJHHHFF@DFFEEEDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDD
@87Q
CTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAAC
+
@?@BDFFFFHHHDHIBEH;CCFFECDGBFGIGEDDHGIGDBBFFFGIGGE@FCEHIC>EHHEFC3;AACCCB?B?<2?88??CCC@@@>CAACCBAACCAC
@87R
CAGCGTCCACTGCTGAAGACAGACATGGAACGTCACATCAACGAGGAGGACACAGTGCCTCTTTCTCACTTTGATGAGAGCATGGCCTACATGCCGGAAGG
+
@@CFFDFFHHHHHJIEGGIJJJJJJJJIIFIGIHIIFGIJJJIIJJIJJGGIJEHIFGHHHDHEEEFFFFEEEDECEDCDDDCDDBCCACDCCDDDDDDDD
@87S
AAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCAC
+
=?@=D>D;?@DD1A:8@:@CEFBGG9BDDFE9DFF38BFFEFEEFBA<ED@=EFFDDDD?A@>;AC>AA;?BBB<<88?<1<>A>BBBB>@AA@B<>?@@?
@87T
CTCCAGGACCTCAGCGAGAAAGGAAGGCATCTTCATCCTCAGAAGACAGGAATCGAATGAAAACACTTGGTACACGGGACTCGAGTGATGATTGGGAGAGT
+
>==1<++22@++2+2)1?))2<5)11):::700:=ABB?0=A>7*=*/.<(.)).=7=7>BA77=()..)..).(5=3=',;5(,,5((+:38822+20(5
@87U
GAAGCACATAAGTCCCTTAGTACAGTGGAAGATTTGAAAGCTGAGATTGTTTCTGCATCTGAATCCAGAAAGGAACTAGAATTAAAACATGAAGCAGAAGT
+
C@CFFFFFHHHHFHIIJJJIFHFGJFHIIIJIJJJJJJJJJJJGIIJJJJJIJIIGIIJIIJJJJJJIJJJJGGJIIJHHGGGHFFFFFFEEEEEEDDDDD
@87V
TTGAAGAATTGAGCTTTTCAAGGGAACAGATTCAGAGAGCTAGACAGACAATAGCTGAACAAGAAAGTAAACTTAATGAAGCACATAAGTCCCTTAGTAC
+
@CCFFFFFHHHGHHGIJEHHIIDCHIIJIHIIJJJJJJJJJJJJIJJIJJHEGIIJIIIJJJIJJIJHIIIHIHHHHHHFFFFFEEEEECDDDDDDDDEE
@87W
TCTACACCACGCAAAGTGATGTATGGTCTTTTGGTGTCCTGCTGTGGGAGATCGTGACCCTAGGGGGAAACCCCTATCCTGGGATTCCTCCTGAGCGGCTC
+
C@CFFFFFHGHHGJGICGHHIHIIGIHGIJIJJJCGGIJJJICHIIJJIIIIIIIJJGGIJJFFHECDDDDDDDDDCCDEDDDDDDCEDDDDDDDDBDD>B
@87X
AGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTTATGGGCAGG
+
@@@FFFFFFHHHHIGGIJJJJJJJIJJJJJJIJIEBHIIGIGJIIGJJJFIIICHHJJJIJHHGFFFEDDDDDDDDDCDCCCDDDD?@@BDCCDDDBCBD
@87Y
CACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGAT
+
CCCFFFFFHFHHHGIJJJJJJIIIJJJJJJJJJIJJFHIIJJIJJFHHGIJJJGIJIIIJEIHHHHFFFDEDCEDDDDDDDDEEDDDDDDDDDBDDDDDDA
@87Z
AGGAGATTGAAAATCTTCCTGCCTTCCCTCGGGAAAAACTGACTCTGCGTCTCTTGCTGGGAAGTGGAGCCTTTGGAGAAGTGTATGAAGGAACAGCAGTG
+
@@<DDD+ABFBFFIEFBGF@:?:FHB@A+A??@GIIC8?F9F9998*9@-7-==@FII@>E>)5..;7;?@;@BA9(;A(,;>,>>@>@AA?B<(38(8(+
@880
CTCAGAAGTGCCTAGCTGCCACTCCATTTATATGAGGCAAGAAGGCTTCCTGGCTCATCCCAGCAGAACAGAAGGCTGTATGTTTGAAAAGGGCCCCAGGC
+
@@<BDDDDDAA<F?E<<FGGACEGHEEBHH>9CEHBG<DC@GGEFGAF>DHEE28BFF@BCHIIGD@EA=EHHCE?DD;@CCDC>C@>>CA<??B=B?@?<
@881
CTTCAAATCAATGAACTTCAAAAAGAAATTGAAATACTCAGACAAGAAGAAAAAGAAAAGGGTACACTTGAACAAGAAGTTCAAGAATTACAACTTAAAAC
+
CCCFFFFFHHHHHJJJJJIJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJFHHJJJJJHHHHHFFFFFEEEEEEEDDDDDDDDDDDDDC
@882
CTGAGAAACAGCACTCATAGTAGCACAGCTGCAGACTTACTACAAGCCAAACAACAGATCCTCACTCATCAACAGCAGCTTGAAGAACAAGACCACTTATT
+
@@CDFFDFHFFHFHIIIIIJEG@HDHGGHIJJGJIIIIIGEGIGIJJJGFGGGIJIJGIIJGEHEGHJIEGHEECHCDDFECEEEEDDDD?CDDCBDDCDD
@883
GGAATTTTTGGGAAATATGAAAAGCCAAAATTTGTGCAGTGTTTAGCATTCTTGGGGAATGGAGATGTTCTTACTGGAGACTCAGGAGGAGTCATGCTTAT
+
:+++<AAAB<)<++A7>CC4?7?=@7=A@=1@B71:??=A<?ABAB7AA7?B97>B:1'88).6>3)>B)7>=.7=;.6>;>99;;(,',5,(5=>??>?9
@884
CACGACATGTGAATATCCTACTCTTCATGGGCTATTCCACAAAGCCACAACTGGCTATTGTTACCCAGTGGTGTGAGGGCTCCAGCTTGTATCACCATCTC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJGIIJJJIJJJJJJJJJJIIJJJJJJGIH?EHFFFFFDDDDDDDDDDBCEEEDDDDDDD
@885
GAATTAATAAGACAACACATGGCAGGGATGGAGGAAGTGAAAACACAGCAAAAGGGAGAAATGGAGAATGCTTTAAGGTCATATTCAAATATTACAGGTA
+
;3((=4..)2)))2)(:(9)4>8)((-(.:?>(9=?(0))0)).<((((9)9..(-;-=>7>8))(8=)9((.666((-4;7;(5(7=;:02(,,5((+(
@886
GATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCC
+
@@@FFFFFGHFFDGBHGGIJGIJJJJGHJCGIGCFGAHGJIIBGEHIJJJIEGHGHJIIJJECHGECDFCF?BDEEEDCCCCDDDCCCCBBDDBD8<ACCD
@887
AATCAATTTGGGCAACGAGACCGATCCTCATCAGCTCCCAATGTGCATATAAACACAATAGAACCTGTCAATATTGATGACTTGATTAGAGACCAAGGATT
+
CCCFFFFFHHHHHJJJJJJIIJJIJJJJJJJJJJJIJJJJJJIHIJJJJJJJJJJHHHHHFFFFFEEEEEEEEDEEDEDEDDDDDDDECDDDDDDDDDDCD
@888
TTTATGGTGGGACGAGGATACCTGTCTCCAGATCTCAGTAAGGTACGGAGTAACTGTCCAAAAGCCATGAAGAGATTAATGGCAGAGTGCCTCAAAAAGA
+
BCCFFFFDHHHHHJIIJJGIJJJJJJJJJIJIJIJJJIJJJJJFHIJJIJIJJIJIHGJHHHHHFFFFFEEECEEDDDDEDDDDDBB@CCDDDDDDDDDD
@889
TGGCAAAGCTCTCCTGCTGCTGACCAAAGAGGACTTTCGCTATCGATCTCCTCATTCAGGTGATGTGCTCTATGAACTCCTTCAGCATATTCTGAAGC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJFHIJJIJHHHHHHHFFFFFFDEEEEEDDDDEFEEEDDD
@88A
CTACTGTAGAGCCCACACCTGGGAAAGGACCTAAAGGGGTATATCAAATCAGCAAACAAATCAAAGCTCATGATGGCAGTGTGTTCACACTTTGTCAGATG
+
8??AAD=BFHHHBEGBEBCACAF??EE9?:8?FH@??):@????DHII@9C=8CCAGDHIC@@@GC>=77?@D3;:;@=66555;5>5@>9::>>ACA:5:
@88B
CTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCT
+
CCCFFFFFHHHHHJJJJJJJJJIJJJIIJJJJJGHIJJJJJJHIIJJJJJGIIIJIJIJJJGHHHFFFFEEDDEDDDDDEEDDDDDDDDDDDDDDDDDDDD
@88C
CCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTGAGTTGCTAAGAGAGAAAACCAAATA
+
@@BFFFFFGHHHHGIJIJJJJJJJJJJJJIJIGEIIJGEIFHGIJEHIEGHEHIIJJIIIHGGIHHFDDDC;AACCDDCDEDDDCD@DDDDDBDDDDD
@88D
CTCCTGAAAGCATCATGTACCGGAAGTTCACTACAGAGAGTGATGTATGGAGCTTCGGGGTGATCCTCTGGGAGATCTTCACCTATGGAAAGCAGCCATGG
+
<?@;DD;?FFFFFI?EFF@CED@GAECG@BEFFE@E@E;F?BGDD?4BGEF989BEF>A<'-;)7..?>>@@@=?>;5;ABBBB:5:@@::??A<?884>?
@88E
AACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCC
+
@@@DDBDDFBHFDGGGB@FFGHGGIHHGI:CFHCHGCDFHHGHGHIEGI?B?BGHGI8C<=CECDHEEHFEFCDDC@C@>ACCCCCC?BCCCBC>:?AC<<
@88F
AAAATGTTGAATGTGACAGCACCTACACCTCAGCAGTTACAAGCCTTCAAAAATGAAGTAGGAGTACTCAGGAAAACACGACATGTGAATATCCTACTCTT
+
CCCFFFEFHHHHHHIIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJIJJDHHIJJ@FHIJJJJJJHHGHHFFDDDDEDEEEEEEEEDDDDDD
@88G
TTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGC
+
<@?DDDDD<3CF+AGA?EFHIEFH>EE>GFE3EE;?F?3;CFBFGBGI6FAFIFEC@@@EE(@=A?)=BDD<@B@.;;;AB?B>?A(9(,;>AB?9>B@<@
@88H
CTGCACCGAGGAGATGTACCGCCTGATGCTGCAATGCTGGAAGCAGGAGCCGGACAAAAGGCCGGTGTTTGCGGACATCAGCAAAGACCTGGAGAAGATG
+
=?=?D;A@FHF?D;FDAE<CGGG@CFADHADBFA?B9?FG2BFBGGHI@=@@A449A@CCBB@>B3;BBCC<@;950>>::::99?93+4??B@CBCCCC
@88I
AGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTT
+
@@??DEFDBDHHDBBHHBGIHCBEA<<;CEGIDIGI@FHD@FHE>DH=?AEGEHIIHGEHHGAEHHCEDBBDFCEEDCC@?BDDD@D?B<???C?B?@@C
@88J
CGGCCAATTACCATGTTCATTCCTTCCGATGTTGACAACTATGATGACATCAGAACGGAACTGCCTCCTGAGAAGCTCAAACTGGAGTGGGCATATGGTT
+
CC@FFFFFHHHHHJJHIJJJJJJJJJJIHIJIJJGIJIIIJIIJIIJJJJIJJJJJIIJIHGIIJIIJFHHHHFFFEFCCEEEEDCD@ABDDDDDDEDCC
@88K
CTAACTAACGTGAAAGCCTTACAGAAATCTCCAGGACCTCAGCGAGAAAGGAAGTCATCTTCATCCTCAGAAGACAGGAATCGAATGAAAACACTTGGT
+
@@@DDDA8FFDB?;4?CB>BFEBF4E3+<?BF4CDF9?DBG*?6?:FEFFBFF=.8@CE;@EE=7?CC;;=7)7@DCCCCABB??BAABB>B2?BBA@:
@88L
TTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGC
+
@@@DDFFFHHGFHBGGGIIGGIIJIGIJIGIHIHIJGIHIIJJIGIJGIGEIECGGGJJIIJGFHHEADFFFFFDC@AC@CDDD@CDBCACCCDBDDD<8<
@88M
CCGGCCGAGTGCTACAACCTCAGCCCGACCAAGGACAAGATGCTTGTGGCTGTGAAGGCCCTGAAGGATCCCACCCTGGCTGCCCGGAAGGATTTCCAG
+
@@@FFFAAF:CDBFDFHHGIGFHHGEG@GHIIIFCFGEGGIIIIGEGEHHHF2?BDDECCCCCCCCC<AC??><?BA9ABCB@BB@B5<@B2>AC>ADC
@88N
AGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCA
+
@CCFFFFFHHHHHIIJJJJJJHIJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJHHHHHHFFFFFEEEDEDDDDDDDDDDDEDEEDEDDDD
@88O
CAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCAC
+
CCCFFFFFHHHHHJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJIJHHHHHHHDFFFFFDECCDDDDDDDDDBDDDDDDDDDDDDD
@88P
GTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACT
+
CCCFFFFFHHHHHJJJJJJJJHIJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJHHHHFFFFEEEDEEDDEEDDDDDDDDDDDDDDD
@88Q
TGCCCACTGAATGTTCATTCTTATGACCCCCAAGGAGAAGGCAGGGTGGATCCTGATCTGTCCAAGCCTAAAAACCTTGCTCCTTTACAAGAGAGTCAGG
+
@CCFFFFFHHGHGGHEIJJHGJIIGHIGIIJIEHIJGIIJJIIFIJ?FHIIJGJJIGCHGAEHGEHFFFFFEEEDDDDDDCCDDDDDDDDDCBC@CCCCD
@88R
CTTGGCCTCTAAACTTAGCCTCTCACCAAGGGAGCATCCCCTCAGTCCTCACCATGCCTCAGGAGGTCAGGGCAGCCAGAGAGCATCCCACCTGCTCCCTG
+
:=8B:;DDHABCFEBHFDHEHIIIIEE@GGGI8CFHI>DFGHHG>?DCFDC9BHGEH:FHGIF7@EA;C@;@?(3;;;5;?;5<ACCCBC9529AAC@BC@
@88S
GTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACA
+
@?@DDEDFHHHHHGFAFFEFGHIIHGGHH>?F@FFGBEHIG@DHGDGGGBFDGFEHIEHECC=;EHIHGC:;?795@A@CB=@?=AB99:>>ACCCC>@
@88T
CGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCT
+
CCCFF>DFHG?DBHGGBDH@DGH<@<@HDGGIIH@GFGH>FAG89DHIGHBFIDE2CCD;CEG@H@>.?A3?BDDDC@BBCBCCC>CC?CAC<@@BBC<?@
@88U
GGAATGTATCGGGAAGGACCCACATACCAACGGCGAGGATCACTTCAGCTCTGGCAGTTTTTGGTAGCTCTTCTGGATGACCCTTCAAATTCTCATTTTAT
+
CCCFFFFFHHHHHIJJJJJJJJJIJJJJIIJJJJJIIJIHHHHHFFFFFFEEEEEEDCDEDDDDACCCCCDDDDDDDCDDDDDDDDDDDDDCDC@DDEEED
@88V
CTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTAT
+
@B@FFFFFHHHHHJJIJJJJJIJJJJJJIGIJIFHIIJGIJ@FHGGHIJIJH?EHEECFFFFFEEEEDDDCCDDDDDDEDCDDDDDDDDDDDDDDDDDDDD
@88W
TCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCT
+
1:17?>A8)<A+??3?22@3<<2>=A**1@=@>AA=A7:=*9?=<==ABBAAABBAA7=15=BAA;>);.>>;;>@@@>3=?:>(--59?99;?95=9<<=
@88X
CTCCTGTCTCTGCTGGAAATGATGCCTATGTTGACCTTGATCGTCAGCTGAAGAAAACTACAGAGGAACTAAATGAAGCTTTGTCAGCAAAGGAAGAAATT
+
?11A=DDDFFBDF@A<FDH?EHIA?<F<92<29<BGEGE<?91::8099?9909B?;9C4CFBF3;6@EEEAEFFFFF>>;;.?B@CCCBCBB?5;;><:>
@88Y
ACACAACACCATGGTTGGCAGTGCGGCCAGCCAAAGCTTTCCCCCTCCTCTGATGATTAAACAGGAACCCAGAGATTTTGCATATGACTCAGAAGTGCCT
+
@@@FFFFFGGHHHIA?EEGHGEHIGGIIJJJIJIJJJJJJIGJJJGGICHHHHHGHHFFFFFFDDAAEDD@=BBCCDDDDDDCCDEEDCDDDDDDCCDD@
@88Z
CTGTGACTCTCACCTCTCAGACAACTAAGACAGATGACCCCCAATTGAAAAGAGAAATAAGGTTAATGAAAAACAGAGAAGCTGCTCGAGAATGTCGC
+
@@@DDD?BFDHDDEH@EAHHIDDE=GHGIIGHIIGEFGI;B@@6?DFEHII3<BHGG@FGFG8)7@EGHHHEEHEEB@CCCA>>C5;?@=<;@@:;51
@890
TTCAAATTCTCATTTTATTGCCTGGACTGGTCGAGGCATGGAATTTAAACTGATTGAGCCTGAAGAGGTTAGTTTAATAGATTTTAATTAGGACACTC
+
<???D8ADBB?:?E@FGEHEFEE?BG??C@A<?6EFDGE8BBD@BFDFAB94=FE@<@=3==CC=@DE)=3?DBDDDDBCB;>A>@@@D>>;;;?@AA
@891
CCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTTATGGG
+
CC@DFFFDFHHHAFB@:A?:C?FGGGCHDBEE@GF@FICHIIII>BHHEIA<FIE>;@DGC=CEHHHFFCBCBB<A?@B???CCAC@:>?1+5<8CAACCB
@892
CGGAGAGCAGTGTGATTCCCTGTGGAGGCACAGTTGCGGCAGCTGCCCTAGAAAAGAGAAACTATTGCAGCTTGCCAGGACCTTTGAGGGCCAACAGCCC
+
=<<2<AAA=B2A2A,7<CCB=A<7A97=A<B@BBBBB=?A=45AA3>BBBBABBB9;37);777.>5>>@>;;;;=?:=:===>?9(+325828228199
@893
GCCAGTGTCCCCACTGCATCATGCATCTCCAAACTCAACTCATACACCGAAACCTGACCGGGCCTTCCCAGCTCACCTCCCTCCATCGCAGTCCATACC
+
=@BFFFFDHHHHHIEIIIJIGIIEJJIJGIIIJIHJIJIGIJIJJJIJIJJJJJJJJJJIIGDFDEEEEDDDACCDDDDDDCDDDDDDDDD?CDDEDDD
@894
CAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCG
+
CCCFFFFFHFFHHJFHGIGIIJJJJJIJJIIIIIJGIICHIFIHIIIIIHIII@FHIGI<HIGJGIHHGG@DEEFEECDECDDDDDDDBBCBCDCDDECDC
@895
CTCCAAGATGAAGGGCTTCTCGTCCTCAGAGTCGGAGAGCTCCAGTGAGTCCAGCTCCTCTGACAGCGAAGACTCCGAAACAGAGATGGCT
+
CCCFFFEDFHHHHJJIJJJJJJJJIJJJJJJGHIJJJIJJIJJJJFGHGFHGIJJIJJJIHHHHHHFFDDDDDDDDDDDDDDCDDDDDDDD
@896
TCACCTTCTCCCCAGCCCTCTTCACAACCTCTCCAAATACACAGACAAACTCCAGAAAGCAAGAATGCTACTCCCACCAAAAGCATAAAACGACCATCACC
+
CCCFFFFFHHHHHJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJHHHHHHFFFFFDDDDDDDDDDDDDDDDDDDDDDDD
@897
CCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTC
+
CCCFFFFFHHHHHJJJFHHGIJJJIJICEGHJJIJGIJJIJJJJJJJJJJIIJGHJIJJJIJIIIGHHFFFFDEECEEEDCDDDDCDDDDDDDCDDDDDDD
@898
ATTGCTGTTGCTGCTATTATTTTTCTTCGTCTTTTTAGGAGGAGGTTCCTTGGCTTTGCTTTTTTTATTCTCTTCCACTTCCTCTTTCCTTTTGTGCTTTT
+
<@@FFFFDDFDHHGGGHGCIIIII9EDFG?8BGHHHBEHHII7DEDGHHHIGGFGGIIIIIGGIIGBDD@CDCEEC<CECCCC>CCCCCCCCCC?ACCCCC
@899
GTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACC
+
@@@FFFFFHHHHHJJIJJJJJJJJIJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJIJJJJHHHHHFFFFFFFEEECEEDDDDDDDDDDDDDDDDDD
@89A
GGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGAATGGCACCGGTGCTTATGATACCACCACTGCTAC
+
?8=BAB+A;CDDBD3CB?C@3<@449?EA9EC>?<BBCD@?((8=B=3@CA@C2(;ACDD);A)33',,>(;>:(,3=9>AA<4>A3>>A(:8(+9A>((+
@89B
ACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACG
+
CCCFFDFFHHHHHJJJJJJIJIJJJJJJJJJIJHI4BGIIJJJJIJIJJJJJIJIIIJJIIIHHHHFFFFFECEEEEEDEDDDDDDDDDDCDDDBDDDDDD
@89C
GTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGC
+
CBCFFFFFHHHHHIJJJIIJJJJJJHHIJJJJJJJJJJIJJJJJJJJJJJJJEHHHHFEFFFFEEEEEEDEDDDDDDDCDDDDDDDBDDDDDDDDDDDD
@89D
ATGACCCCCAAGGAGAAGGCAGGGTGGATCCTGATCTGTCCAAGCCTAAAAACCTTGCTCCTTTACAAGAGAGACAGGAGTCTTACACAACTGGGACTCCC
+
??;DD;ABD?A:<E@+<AF;CFE:1:?)::B4??*??80BB//=CD<C>@D;@D;;77)7?777@;;)666(5(55=85,9AAD:5A54<2:9><<<23:>
@89E
GAAAGATTGATTTTCTTAGACTCCATTAAGTCCAAATCCAAAGACTCTGTGTGGGAAAAAGAAATAGAAATACTTATAGAGGAAAATGAGGACCTCAAAC
+
@@<?DDDDDBFAAE@BEBCCHHDGHHICGHEHIGG@DF@ECGF3:?<BF?B:?D:BDB8BFGHDH@::CEEHCE@CEHA;ABBBCCEECEE;;;=>>@@>
@89F
CAGCTGAAAAGTCACATAATTCTTGGGAAAATTCAGATGATAGCCGTAATAAATTGTCGAAAATACCTTCAACACCCAAATTAATACCAAAAGTTACCAA
+
C@CFFFFFFHHDHGIJJJIJGIHIJJIGHIJIJJIGEFHFHFIIIIGIIJIJIJJIHIJIIJJIJJJJJJHHHHHFFFDCEEECEEDDDDDDDDDEDDDD
@89G
GAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGAC
+
@@BFFFFDHGHDFGIJJJIGJJHJJIHHHIIIIIDGGIGGHHGIIJIEHIG<EHEGFFFFEEDEEEDCDDDD@DDDDDDDDB?ACDDDCBCDDACDDDDDD
@89H
GGCAGTTTTATGATGACACCTGTGTTGTCCCAGAAAAATTCGATGGAGACATCAAACAAGAGCCAGGAATGTATCGGGAAGGACCCACATACCAACGGCG
+
;?;AD+BBBDDD?2CEEAAE?F?E4CCFEFII??CDB8?BCD99B:DDDCDDDCEEECDB@ACDA@DDDAD7?AC;9?3=>??>=?<?<>>A?:>?2599
@89I
CCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTA
+
@@CFFFFFGHHHHJIIGIGIJJJJJIFGJIIJIJGIGGHICFHIJJJJCHHGFHGIIJJHHFHBB>@ACDDDD?BDDDD@DDCCDCDCDCDDCDDBDDDD
@89J
CAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATAT
+
@<@DDDDB=CFHHEEHG4CEIIEFH?FGIGG?<FGAE?DHGICDHGHBBGCHB<BFCCDGGGGIH=ECDEC>B?CCCCC3A???BBCCC@AC5:ACDAC
@89K
ACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACG
+
CCCFFFFFHHHHGIJJJJIJJJJJJJJJJJJJJJJJJJJJJJJIJJJIJJIJJJJJJIJJJIHHHHFFFFFECEEEDEDEDDDDDDDDDDDDDDDDDDDDD
@89L
CAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTTATGGGCAGG
+
CCCFFFDDDBBFFGGBFGHIIHHGIGDGGGG9EHG@GHGGBHBHEGIIGBFGIJIFAGHJIED<E6<AEDDDDDBBDDACDDCAABB395<ACDDCB?9>B
@89M
CGCTATTACTATGAGAAAGGAATTATGCAAAAGGTGGCTGGAGAGAGATATGTCTACAAGTTTGTGTGTGATCCAGAAGCCCTTTTCTCCATGGCCTTTCC
+
CCCFDFFFHGHHHIIIJJIJIJIIJJJJGIGIJJ?FGIJJJIJGHBFFHIHIIIIIIIGHIHIJGGGGHGHHGHHHHFFFEDEEEECDDDDDDDDDCDDDD
@89N
TGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGG
+
@@<=DD;DD4C<AF98CBF:CEAFFCGCCGFAG9:9?D@BAC@=B;@C@FEFAE@@C>EFF>A)=B>BBDACC?@BB8<5<B>@A@4@@82?@<(4>B>><
@89O
GGGAGCCCTGCCCCAGGGGCCCATGCAGAATGCCACCAAGTATGGCAACATGACAGAGGACCATGTGATGCACCTGCTCCAGAATGCTGACCCCCTGAAGG
+
?@:?=@DD8FCF?GBGB@@FC???G>D?BF*0?DDBDF;F9B8B8B=F@(@F=DCEF;EA;.6;@);;36;>A;>?B;>@BBAA>::>>:?BB?>5@3@>B
@89P
GATGGGACTTCAGAGGCTCTGCCCCTTTGTTGGCAGGGAGGCTTCCAGCCTGAGAGCACTCCCGGTTTGGATGCTGGGCGTGCATAGCTGGCTCCTCTGC
+
;51(-(2=>@1=<;491:7)@))2-3=;))2(:?)-9=(<((<>)6)))5=99910=0:)<>/''3396;7;;<5;5(,'))52((+(((362286(3:(
@89Q
AACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTAC
+
CCCFFFEFHHHHHIJJJJJJIIGIIJJJJJJJJJJGHGHIIJJJJJJJIGIJGIIJIIJJJJHHHHFFFFFECEEEEFEDEDCDDCDDDDDDDDBDDDCDD
@89R
GGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGACTGC
+
?<@DFDFFFDFHHIGGIIIIIIIHIIIIIGHGGIIICDHGIIIIIIIIEGIIIIGIIII=DGHFHGGHEFFFFDBCCCDCDDDBCCCDD@>@DDB@C?CCC
@89S
CTTAGGAGTTGGAAGTGGAGAAATCAAAGTAGCAGTGAAGACTTTGAAGAAGGGTTCCACAGACCAGGAGAAGATTGAATTCCTGAAGGAGGCACATCTG
+
?@@FDFDDADFHFIJBEBHFFIIIJGIIICHIIJIEHHGIGHJJJJIJJJJJJIEHIGIGIJIIJJIIIIEHGEHF>CCFDDEDDEEC>ADDBBB?CCCC
@89T
GGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCC
+
8;?ADA;ADFFF?@<AEGIEHH@CFH>GDGCBA@EFGDFB?B>GECHGIIEGCGIIIDHHFGDCGHIHECA>A@;?>@BCCDC@CCCCCCCCCB<CCCCCC
@89U
CCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATG
+
CCCFFFFFHHHFHIJJJJIGIJJJJJJJJJHGHIIIJJIJDHEHGJIGHIIGIIJJIGIJJIHEBHFFFFFEECEEDEDBDDDDDDDDDDDDDDCDDCCCD
@89V
AGGCCCTCCAACCCCCCCACACCATCCAGCACGCCAGTGTCCCCACTGCATCATGCATCTCCAAACTCAACTCATACACCGAAACCTGACCGGGCCTTCCC
+
@CCFFFFFGHHHFIJJGGIIIGIJJIICFCHG;AHGIJJJHHHGHFFFFEDEEDDDDEDDDDDDDADDCCCDDCDDDDDDDDDDDDDDDDDDDDDDDDDDD
@89W
CCCGAAGCCATCCAGCCCCCGGCAGGAGAGCACACGCGTGATCCAGCTGATGCCCAGCCCCATCATGCACCCTCTGATCCTGAACCCCCGGCACTCCGTGG
+
CCCFFFFFHHHHHJJJJJJJJJJIJJJIIJJJJJJJJIHFFFFEEEEEEDDDDDDDDDDDDDDDDDDDDDDDDDDDDEDDDDDDDDDDDDDDBDDDDDBDD
@89X
CTATTTTCTTATTTTCACAGTATAAGAAAATACCTACTTAAGATTCATTTGGAGGCATGTCTAAATCTAGTAATTTATTAGAAGCTTATCCATCCCTATT
+
C@@FDDFFDDBFBHGGBGIIBEIIIIGHGC@FHH9AGCEHIIGIE<CGIIIIHHFIIIIGF@FGHGCHHIFHIGHGHIDHGH;7DAEHHHFDF>@DAC@@
@89Y
CACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACC
+
CCCFFFEFHHGHGJIJIJJJJJJJIIJJJIJJJJJJJJJJIIJGHIGGJJJJJJJJJJIIIJIJJJHHHHHFFFDDCDDDDDDDCDDEEEEEDDDDDDDDD
@89Z
CGTAGGGCATCCCAGTGATCTGTGGGCAGAAGGTTGCTTCCCATTGCTAGAAAGTGGTGATTCCACACTGGGGTCTTCCAAAGAAACCCTTCCACCCACAT
+
@@@DAADFBDFFFGIGGIJJJJHHJJIJJGHIIJHIJJJJGGDFHHH>GHDHIIHEGFFHGI;A@FD?GEH;A9BB@@EC>AEDBCCDDDDDCCDDDDDDC
@8A0
CCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATAT
+
CCCFFFFFHHHHHJJJJJJJJHJJJJJJJJJJJJJJJJJJIGIHIIJJJFGIJJJJJJHHFFDDDDDDDDDDDDDDDDDCDDEDDCDDDDDDDDDDDDDDD
@8A1
GCTCTCTCCAACAGGCTTGCAGCCAATTTACTGGAGCAGGGATGACGTAGCCCAGTGGCTCAAGTGGGCTGAAAATGAGTTTTCTTTAAGGCCAATTGAC
+
C@@FFFFFHHHHHIIIIJJJIIIIHIJIIJJFJJIJJGIIJGCHGGIGIGHIJIIGHGE@HFFH=AEFF@CEEEEECDC@CCDCDDDDDDDDDDDDDDDD
@8A2
GATTAATGGCAGAGTGCCTCAAAAAGAAAAGAGATGAGAGACCACTCTTTCCCCAAATTCTCGCCTCTATTGAGCTGCTGGCCCGCTCATTGCCAAAAATT
+
?<@BD:D88B:A:C<ACFEE>AHH?GD@?FFGI9?BDA9D?:BD;9/?B<D>C=;FF@)=F;;AE<6?CDDBB7;@A3.;>@BB=8;=5@A@BAAA<28?:
@8A3
CTCACAGCCTCGTAAAAGGCGGTGTGACAGTTTTGTCACGGGCAGAAGGAAGAAACGACGTCGTAGCCAGTAGGGAGCAGCGGGACCATCTGACCCCACTT
+
CCCFFFFFHHHHHIJJJJJJIJIHIIJJJJGIIJJHIJJJJGJJJJHHHHFFFFFEDDDDBDDBBDDDDDDDDDDDDDBDDDDBDDDDDDDDDDDDDDDBD
@8A4
CATGCACCCTCTGATCCTGCACCCCCGGCACTCCGTGGTTTTCAAACAGTCCACGCTCTCCGAGGGCGGGCTGCAGGGGGAAGGAAAGCCCAACAACCTCT
+
875@=:).:(.4<<)8<9:))38=?8=?2(<:<=17(-((.())/.8.).)).)(5'3=;=/'',',&)59&0((((&)&&)(+((++386:(28(222:/
@8A5
AGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGAT
+
CCCFFFFFHHHHHJJJJJJJJIJJJIJJJHJHIHJJIJJJJJJJJJJJJJJJJIHIJHHHHHFFFFFFEEDEEEDDDD@BDDDDDDDDDDDDDDDDDDDDD
@8A6
ATTTCTCCCACCAACTTATGACCCACCAGACCACCCACTCAGGGAGCGACCTCCACGGCCCATCAAGCCTTCAGTATTCTCTCCAGACAACCCTCTGATGT
+
++++?,=2+AACB=7=A+,+<+3+?ACBB)1:?5)0:0):**00=AA';AAA;2)7(5<=';35=(,98(;(,5;3+33:(+88(4:;(++259(8(+3((
@8A7
GCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGC
+
CCCFFFFFHHHHHJJJJJJJJJIJJJJJJJJJJJJJIJJJJJJJJIJJIJJJJJJJJJJJJJJJHHGHHHHFFFFFEEEDEEEDDDDDDDCDDDDDDDDDD
@8A8
CAAACCAAAGAAAAAGGAGAAAGACAAGAAGGAAAAGAAAAAAGAAAAGCACAAAAGGAAAGAGGAAGTGGAAGAGAATAAAAAAAGCAAAGCCAAGGAAC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJIJJJJJHHHHFFFFFDEEE@CDDDDDDDDDDDDDDDDDBDDDDDDDDDDDDD
@8A9
CCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCT
+
@CCFFFFFFHGHFIGIJIJJIJJJJIIJJJJEIIGHGIIIIGGIGIIJIHJIGGGIJIJFIIHIJJHHHHHHFFFFFEEEDEDDDDDDDDBDBBDDDDBD
@8AA
CTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTC
+
CCCFFFFFGGFAFGEGIGIIGEHIGHFFIJIJJJJJGGIJIJJJIGIJJIEGGIIIJIIIIIIAAEEHED?ADCCBDDCCDCCDBDDDDD@CDDCCCDDDD
@8AB
TGAAAAGGGCCCCAGGCAGTTTTATGATGACACCTGTGTTGTCCCAGAAAAATTCGATGGAGACATCAAACAAGAGCCAGGAATGTATCGGGAAGGACCC
+
@C@FFFFFFGHHHIGEIIIFEHHGIJGGIEEHIJIIFHIJGIDHIJIIIJIIJJJJJIGGHEHEFHHFHFFFFDDEEDDBBBDCCCCFDBDDDDDDDDDD
@8AC
CAAAAATTACAGATTCAATTTCAGCAATTACAGGCTAGTGAAACTCTGAGAAACAGCACTCATAGTAGCACAGCTGCAGACTTACTACAAGCCAAACAAC
+
?;@A;D?DFD?<CFEGIFBF@H>FHHIFDEFA29?8?EF@C<DEDDG@?*0BG;;?()?8BC8=F8@4@AF>@D>@?E77?BD@B3?:>;;65??=;=5<
@8AD
ATTTACTGGAGCAGGGATGACGTAGCCCAGTGGCTCAAGTGGGCTGAAAATGAGTTTTCTTTAAGGCCAATTGACAGCAACACGTTTGAAATGAATGGCA
+
1=?:ADDDD=2CB+:6:C::AEA<FF@G;D:DF7309990*?DF;D?B9BDF9F.>CF>@@7..=C3666;@B;7@6=>BB;585<<83:5:5((;5:8>
@8AE
CCACCACAAGGCTTTAAGCAGGAGTACCACGACCCAGTGTATGAACACAACACCATGGTTGGCAGTGCGGCCAGCCAAAGCTTTCCCCCTCCTCTGATGAT
+
CCCFFFFFFHHHHJJIJIIJJJJJFHIIDEIJIJJIGIIGIIIJIIGIIIIEIIIIHIDEHHFFFDFEDDDDDDBDBDDDDDDCDDDDDBDDDDDCDDDDE
@8AF
CACTGCTCCTAGAGCCCTCTTCGCTGACTGCCAATATGAAGGAGGTACCTCTGTTCAGGCTACGTCACTTCCCTTGTGGGAATGTCAATTACGGCTACC
+
@@@DD?DDADDDBBFIIDFDHF;@G<8?CGHI<?CGGBHFEDFBAFBFHHDFDBC==FAC6CHBC=;;AE>?CDCD>@;3(-;>;;@;@C:C?:/9B?C
@8AG
CAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATAT
+
@@@ADDDFDBDFHIJIIGIGIGHIIECFHHJJJJJJGFHIJFFGFHIJJIIJJIIEEGEGHIGHEHE=BCB;CD@CCCECDDBDB@C@CCDC>CCC>>C
@8AH
CAAATACCATAATTACATGCGGTAAATCTCATATTTTCTTCTGGACCTGGAGCGGCAATTCACTAACAAGAAAACAGGGAATTTTTGGGAAATATGAAA
+
@@@?DDDDDBD?BGDGABFGHGFDC9C<9?EEBGEGIEFHGI<B?BDDHEGGDFBHIEIFE;CCEBBDEEA@>>@@?BB=?BCCCC@@B<CBCCADDDC
@8AI
CCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATG
+
CCCFFFFFHHHHGJJJJJJJJJIJJJJJJJJIJJJJJJJJJIJJJJJJJJJJJJJIJJJJJJJHHHFFFFFEEEEFEEDDDDDDDDDDDDDDDDCDDDDED
@8AJ
GCAAGAAGGCTTCCTGGCTCATCCCAGCAGAACAGAAGGCTGTATGTTTGAAAAGGGCCCCAGGCAGTTTTATGATGACACCTGTGTTGTCCCAGAAAAAT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJIHIJJJJJJJJJJJIJJJJJJJHHHHFFFFFFEEEEEEEDDDDCDDDDDDDDDDDDDDDD
@8AK
GCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGC
+
@@@ADBDE>FFHFEHIGHGI4AHGFHEGHGICGIJ93?<BF??<BGHIHIA(?DB'@4@>=@G@E=;ACCHFF;9@>(6;@;ACDDCBDCCCCBA:AACB8
@8AL
CAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGG
+
CCCFFFFFHHGHHJJJIJJJEHHIJIJJJJJJIJJJJJJJIHIJJJJJJJJJJJIIJIJIGIHGGHFFFFFEEEEEEEEDDDDDDDDDDCDDDBDBCDDDC
@8AM
AAGCTCTCCTGCTGCTGACCAAAGAGGACTTTCGCTATCGATCTCCTCATTCAGGTGATGTGCTCTATGAACTCCTTCAGCATATTCTGAAGCAGAGGAA
+
CCCFFFFFHHHHHIJJJJJJJIJJJIICFHIIIJJIEHIJGIIIJGIIHGIIEGH=F@FHHIGIIJJIJHFHDHHFFFFFFEECEEDEEEDDDDDDDDBD
@8AN
TCCAGCACGCCAGTGTCCCCACTGCATCATGCATCTCCAAACTCAACTCATACACCGAAACCTGACCGGGCCTTCCCAGCTCACCTCCCTCCATCGCAGTC
+
CCCFFFFFFHHHHHIIIJJJJIJJJJJJJJJJJJJJJIGGJIJJJJJIIJJIJIJJJJJIHHHHHFFFDDBDDDDDDDDDCDDDDCDDDDDDDDDDDDDDC
@8AO
AGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACT
+
@C@FFFFFHHHHHJJIJJJJIJJJJJJJJIJJJJJIJJGIIJJJJIJJJJJJJJIJJJHIJIHHHHHHFFFFFFEEEEDDDDDDDDDDDDDDDDCDDDDDD
@8AP
AAAAAAGAGGAATCTCATTCTAATGATCAAAGTCCACAAATTCGAGCATCACCTTCTCCCCAGCCCTCTTCACAACCTCTCCAAATACACAGACAAACTCC
+
@@@FFFFDFFFDHIIIHIHIJAECGHGIGICH@FGHGIIBHGIIFEHIIGGIACGIJJJIIJJIHFFH@?CFFFCDCCE@CDCCDDDDD>CBAA?9ABCC>
@8AQ
CAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCC
+
?8?:A)0A?BDDDEII;EBCD=D13B;B?9?DAABDD;).//747;8@;A9777=>5)5;.);@A;@=;;9(5:9???((5:(:<>>4((4::>++9A<<
@8AR
TCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGC
+
CCCFFFFFHHHHHJJJJJJJJJJJHIJJJJIJJJJJJJJJJJJJJIIJJJJJHHHHHDEFFFFEEEEEEEDDDDDDDCCDDDDDDDDDDDDDDDDDDDDDD
@8AS
GACTGGACAGTTACCTTATTCAAACATCAACAACAGGGACCAGATAATTTTTATGGTGGGACGAGGATACCTGTCTCCAGATCTCAGTAAGGTACGGAGT
+
CCCFFFFFHHHHHJJJJJJJJJJJJIJJJJJIJJJJJJJJJIJJJJJJJIJJJIJJBGIJJJIHHFFDEEEEEEDDDDDDDDDDDDDCDDDD:ACDDDD@
@8AT
CAAAGGAAGAAATTGCTCAAAGATGCCATGAACTGGATATGCAGGTTGCAGCATTGCAGGAAGAGAAAAGTAGTTTGTTGGCAGAGAATCAGGTATTAATG
+
?8?+A;==AADAA<<:2C4<AFFBFI@?FFA??C<9CCDI<99:800?0099/?DE40=@6=8(==C===A7@7;7==?@=77=,;@>;A>5>-55;BDD>
@8AU
GCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACT
+
CCCFDDF?HF?>FHGII8CFHIIIIHCECFHIGIIIIGHGIIIIIIGIGIIIIGIGCGIDGIIGIHEFFFFDECEECECD@CCCCCCCCCCCCCCEC@CCC
@8AV
CCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGT
+
CCCFFFFFHHHHHJJJJJJJHIJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJHHHHHHFFFFFFEEEEEDDDDCDDDDDDDDDDDDDDDDDDDDDDDDDDC
@8AW
CCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCG
+
@CCFFFFFHGHDHIJJJJJJJJJIJJJJJIGIJJIJJJJJJJJJJJJJJIIJJJJJJJJJJJJJJJIIGGHFFFFFEDDEDDDDDDDDDDDDDDDDCDDDD
@8AX
CACACCATCCAGCACGCCAGTGTCCCCACTGCATCATGCATCTCCAAACTCAACTCATACACCGAAACCTGACCGGGCCTTCCCAGCTCACCTCCCTCCAT
+
B@@FFFFFHHGHHJJ@FGIJHIHIIIJJIJJJIIJJJIJGGJJJJJJJIJJJJJIIJIJJJJJJHHFFFEDEEEDDDDDDDDDDDDDDDDDDDDDDCDDDD
@8AY
GTTTGTGTGTGATCCAGAAGCCCTTTTCTCCATGGCCTTTCCAGATAATCAGCGTCCACTGCTGAAGACAGACATGGAACGTCACATCAACGAGGAGGAC
+
C@CFFEFDHHHHHJJJJJJJJJJJIJJJJJJJJIJJJJJJJJJJJIIIJJJIJJHIJJJIJJJJJJIJJJHHHHFFFFFFDDDDDDDDDDDDDDDBDDDD
@8AZ
GCTCTCCGACAGCGCCAACGCCAGCTGTATCACCTGGGAGGGGACCAACGGGGAGTTCAAAATGACGGACCCCGATGAGGTGGCCAGGCGCTGGGGCGAGC
+
@@CFFFDDHHHFGJJJJJGIIJJIJIJIJJIJIIIIIJCHIGGEFFFDCDDDDBB?CCDEDCCCCDDD@BDDDDBBDDDD>ABBDDBD?B@<BDDDDDBDD
@8B0
CTCAATTTCTGGCAGATCTGCTCGCCCCAGGAAAACAGAGGGATCCCATGGACTTAATTGGGGGGCTAGCGCAAGTAGACGGACTCACCCTTGGCCAGCTG
+
7;95;)))))=8)2(29)..>9)(2((1<5((())0=))6(7;>=1))).)):6=)=)).)(,')5828/55&&&((+(())&0)8(2(+685((588:;5
@8B1
AGGAAAGCCTACAAATTTATTAAGGGAAGAAGAATTTGGTGTTGATGATTCTTATTCTGAACAAGGAGCACAAGACAGTCCGACTCATCTAGAGATGATGG
+
@@@FDBD;FDDHDDBGGEIIIGIHCHIGGJIIHGIIJJI?FBFHEGGIIIHHIHIIIIEGHGGIIGIGCCHEEAEAEECBDACBBDDDDCCC>A>AA:@CC
@8B2
ATAATTACATGCGGTAAATCTCATATTTTCTTCTGGACCTGGAGCGGCAATTCACTAACAAGAAAACAGGGAATTTTTGGGAAATATGAAAAGCCAAAATT
+
CCCFFFFFHHHHHJHIJJJJJJJJJIJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJHHGHHFFFFEDDDDDDDDDDDDDDDDDEEEEDDDDDDDDDDD
@8B3
GTGGTCTTGTTCTTCAAGCTGCTGTTGATGAGTGAGGATCTGTTGTTTGGCTTGTAGTAAGTCTGCAGCTGTGCTACTATGAGTGCTGTTTCTCAGAGTTT
+
@@@DB?DD>A<CDFFEBF3<:C?E?FH:FHI322?@@BD@FEC<???B???9DDFEBBBBB8=C==F;=FF=DEF>E;CCCFE)77?BD;;6>@A>BB>AA
@8B4
GCTGTCTGACCATTTGTTATTTTTCGAAGAAACTATGATATAAGGGGAATAAAAGTCAGGAAGATTACAAGCAGCGTGATGAAAAGAAGGGGGCGGACATG
+
(((2(2)2)21))=):).))3))33((2(=>7)))))))2)))0.((-77<1)9)))))))(..<)3)3))((.(,('(...:1-0,990''0&&)5)&(+
@8B5
AAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTAC
+
CCCFFFFFHHGHHJGIGHIJJJJJJJJJJJIJJJJJJJJJJJJJJHGHIJJJJGHHHFFFFDEEEDDDDDDCDDDDDDACCDDDDDDEDDECDDDCBDA>C
@8B6
AGTGAGTTGGCTGGGAAGCAGCATGAGATTGAAGAGCTAAACAGAGAGCTGGAAGAAATGAGGGTTACCTATGGGACTGAAGGACTGCAGCAGTTACA
+
@C@DFFFFHHHHGJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHIHHHHHHFFFFFEDEEEDDDDDDDDDDDCDDDD
@8B7
CTACAACCCCACGTCAGAGTGTGGGATTCTGTTACTCTATCCACACTGCAGATTATTGGACTTGGCACTTTTGAGCGTGGAGTAGGATGCCTGGATTTTTC
+
CCCFFFFFHHHHHJJJJJJHHHHIJIJJJJJJJJJJJJJJJJJJJJJJJJJGIJEIIJJIJIJIJJHHHHHHFDFFDABDDD>CCDDDDDDDDDACDDDDD
@8B8
CCTCAACAAAAGTCCTCCCCTTGGAGGGGCACAAACGATCAGTAAGAATACAGAGCAACGGCCCCAGCCAGATCCGTATCAGATCCTGGGCCCGACCAGC
+
CCCFFFFFHHHHHIJJJJJJJJJIIJJJJJJJJJJJJJJJJJIIJJJJJJJIIIJJIHHHFDDDDD=?BDDDDDDD@DDDEEDDDDDDDDDDDDDDDDDD
@8B9
AGATAATCAGCGTCCACTGCTGAAGACAGACATGGAACGTCACATCAACGAGGAGGACACAGTGCCTCTTTCTCACTTTGATGAGAGCATGGCCTACATGC
+
@CCFFFFFHHHHHJJJJJJJIJIIIIIJJIJJJJJJJIJIJJJIJJJJIIHIJIJIIJHHHHFFFFFFEEEEEEDDDDDDCDDEDDDBDDDBDDDDDDDDD
@8BA
TTCATTTATGTGTTATTGATGACTCCAATGAGCATATGCTTACTGTATGGGACTGGCAGAGGAAAGCAAAAGGAGCAGAAATAAAGACAACAAATGAAGTT
+
CCCFFFFFHHHHHJJIJJJJJJJJJJJJJJJIJJJJJJJJJJJJJIIJIJIHIJJJIJJIIIIJJJJJJJJJIIHHHHFFFFFEEEEEEDDDDDDDDDDDD
@8BB
GCCTGGCTAATGCCTGCTATGCAATACATACTCTTCCAACCCAAGAGGAGATTGAAAATCTTCCTGCCTTCCCTCGGGAAAAACTGACTCTGCGTCTCTTG
+
@@@DDDDDHFBHHBGGEHG<CHHB?EGHGBFED1???E<?:DGGE>FFB6?FHCCCHC<CH=CGGGGIGHG@;AEEEBA<B?@BA>A>CAAC@?89><ACC
@8BC
GTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGC
+
@=?DDADDH:DFFIGIIIIE@EGAGA<EGGIGGBDHEBG@GHHIHGEGHGGG@CEFD:DGGG@=AHFFBBEEEECE;@;>;>AA:>@C?<@?>?C>CBBAB
@8BD
CCCAGGCATATGGGCAACAAAGATATGGAACCTATGGACAGCCCACTGATATCAACTAAACCCAGGCTCAGACCACTGCAACCTAAGGGCAGACCGCCTAT
+
;(;=((:?)))))((.((;>())@14>8>??;>))))).<(((-.0<)))))/<))9.)<>)((.(6(.<8)3(8=>>8.4;<7;(,(((,;(86-55964
@8BE
AACCAACCCAGCCTAGGATATGGACAGAGAAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCC
+
???;B+2@DDD>D:CEDE?C3<AFC@1C*):C9:BD@*:?000?B69?BDIAC4=B;254=@;7@?CAAAD;;;>6>(;>35(5;A:5=,(><>A5<?A22
@8BF
TTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGC
+
CCCFFFFFHHHGGJJGIJJJJJJJJJJJJJJJJJJJJIGGIJJJJJJJJJJIJJJJJIJJJIJHHEHHFFFFFFECEEEEDDDACDDDDDDDDDBDDDDBD
@8BG
CATCCCCTTCCCACCACAAGGCTTTAAGCAGGAGTACCACGACCCAGTGTATGAACACAACACCATGGTTGGCAGTGCGGCCAGCCAAAGCTTTCCCCCTC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJIJJJJGGIJIJJJJIJJJJIHIJJJIJJJIHHHHFFFFEEEDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDD
@8BH
AACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJHIJJJJJJJJJJJJJJJJJJHIJJJJJJIJJJJJJJJHHHHHFFFFEEEEEEEDDDDDDDDDDDDDDDDDDD
@8BI
CGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCG
+
??<DB@0A:DD:<ABE@8CE:DA1??BDID@?BDDBDE></@8;AAAA<>A;;;@>@;@AAA;>A>???AAAAAA>?5>9><>>?><>>>:>3>>::>>35
@8BJ
GTACAAACTGCATCAGGAGATATGCAAACATATCAGATCCGAACTACACCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATGACATCTCCTGTGACTCT
+
@@@FFFFFGHHHGJJGCHEGGHHIJJJJIJIJJJJJJIJJJJIIJJJGIIJEGEHJJJIIJGIIJGIIIGHHHHFFCBE@BEEEEDEDDDDDCDCCEDCDD
@8BK
GAAAGGACTGTAGAGCTAATGTTTACCTTCTTCCGACCGGGGAAATAGTTTATTTCATTGCATCAGTAGTAGTACTATTTAATTATGAGGAGAGAACTC
+
CCCFFFFFHHHHGJJIJJJJJJJJJJJJJJJJJJJJJIJJJJIJJJJJGIIHHHHHHHFFFFFFFEEEEFEEDFEEEEEEFEDEEEDCDDDDBDDDDDD
@8BL
CTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGAC
+
CCCFFFFFGHGHGIJJIIIIJJIJGIJIJJIJJJJJJJJJJJJIJJJJJEIJJJJJJJIJJJIJJIHHGHHFEFFEDDDDDBDDDDDDDEDEEEEEDDD
@8BM
AATAAATGAACTGAATATAAAATTGCAAGATACTAACTCTCAAAAGGAAAAACTCAAGGAAGAACTAGGACTAATTTTAGAAGAAAAGTGTGCTCTAC
+
@@@FFDFDAFHHFGHHGHGIHIIIJGIIJIIJJJJJJJGJJJIJJIHIJJJJGEGGIIJIJJDIHGIGIHGIJJJHHDHBHFFFFFED;C;@CDCDCC
@8BN
GACACGGGCCCCCCGCCGGCGTCAGCGTAAAGCCCAGAGACCTCCTGCTCCTGAGGCACCCAAGGAGATCCCACCAGAAGCTGTGAAGGAGTATGTTGAC
+
CCCFFFFFAHFFHEHGHGIIIHHFFDDDDBBA>ABDDDD?CDDDDDDD@ACDC3<?@<??BDBBDBDBCCDDDDBDDBDDDDD:?C@AAAB9?CABCACD
@8BO
GGCCCTGGAAGAGTGGCCAAGATTGGAGACTTCGGGATGGCCCGAGACATCTACAGGGCGAGCTACTATAGAAAGGGAGGCTGTGCCATGCTGCCAGTTA
+
@@@DDDADAF?DA<AAFHGGEFEHHIHHBFGGBGGBB6FHIIIIB@@GE@@C@CHDFEDCC??8@@>CDCD:A@AB@B<-8ABACCCCCCCCCCB>A:@C
@8BP
CCACTCTTTCCCCAAATTCTCGCCTCTATTGAGCTGCTGGCCCGCTCATTGCCAAAAATTCACCGCAGTGCATCAGAACCCTCCTTGAATCGGGCTGGTTT
+
<@@BFDFFHB>FHGGIDGIIGIGGGGGGGDHIECH>FGGGIGIGGGGIGGHEIIGHIIEHHHHHFDCD5;A@DCDDDCCBBB@BCCDCDDCBDB<>@D+:?
@8BQ
GAGAAGAATACCATGTATATGCAGAATACTGTCAGTCTAGAGGAAGAGTTAAGAAAGGCCAACGCAGCGCGAAGTCAACTTGAAACCTACAAGAGACAGG
+
@?@ADDDDAFFFHBGA<2ACH@C?CFHCCEHEFBB??C:9EFGIAFHG4?DGHIGED8@FHC6CF@BBAB<A;;5>>CC(5>:CCAB>@C:>@9(3??CB
@8BR
ACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGT
+
CCCFFFFFHHHHHJJJJJGHHIJJJJIJJJIIJJJJJIJJJJJIJJJJJJJJJJJJJJJJJJJJJJJHHHHFFFFFDDDEEEEDDDDDDDDDDDDDDDDDD
@8BS
CTCAGCAAGGTACAACTATTCTTCAGTATGCACAGACCTCTGATGGACAGCAGATACTTGTGCCCAGCAATCAGGTGGTCGTACAAACTGCATCAGG
+
@<@FFFFFHGF?FEEBBFFGIIIIDHBEDHG<DCFHHIBFHEHGGGGB9DGH>FH?DDAFBBFEHHFEDGHCCEE.7;:7==AABCCBCC@3>CC>A
@8BT
TAATTTTAGAAGAAAAGTGTGCTCTACAGAGACAGCTTGAAGACCTTGTTGAAGAATTGAGCTTTTCAAGGGAACAGATTCAGAGAGCTAGACAGACAAT
+
CCCFFFFFHHHHHJJJJIJJIJJJJJJJJIIIJJJJJJJJJIJJJJJJIJJJJIHIJJJIJIJJJJIJIJJJIJHHHHHFFFFFFEDDEEDDDDDDDDDD
@8BU
GTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACT
+
@@7D;D>:?AFADGEFEB@EAGEEEHFEEIIFEGCBBDGFFFFB>@@BFBD<FC@FFFEFIAEE@EE@CF>C?D@?2>;6.(;>B3>3@A@:<>9<?85>B
@8BV
CATGTTCATTCCTTCCGATGTTGACAACTATGATGACATCAGAACGGAACTGCCTCCTGAGAAGCTCAAACTGGAGTGGGCATATGGTTATCGAGGAAAGG
+
???DD:D,2C?DBDBEEEFDBBAD:?FF9E@BA<?9E?@??C:DDDDB)7??DE8BC9A@@C7AD=;7@;C;ADAD@65;@;6(5;AAA>A3<5583=><8
@8BW
GAATGGAAGAGCAAGAACAAGTCGCCTGTTACTTTTGTTCATTTATAATGTTGGTGTACTTAGTAAAAAAAGGCATCTGGAAATTCTATTATTCAATGTCT
+
;(((5))2)(()2.).)8<6)))(((((28))))))2:33)))06=)0.3<)0(((.).99)))/))833,'((..(7((-(((((,((,(((,((((((+
@8BX
CTTGTTGAAGAATTGAGCTTTTCAAGGGAACAGATTCAGAGAGCTAGACAGACAATAGCTGAACAAGAAAGTAAACTTAATGAAGCACATAAGTCCCTT
+
@CCFDDFFHHHHHJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHJJJJJJJJJIJIJJIGHHHHHHHFFFFFFEEEEEDDDDFDDDD
@8BY
CCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTAT
+
CCCFFFFFHHHHGJJJJJJJJJJJJJIJJJJJJJGHIJJJJJJJJJJJJJIHHHFFFFFEEEEEDDDEDDDDDDDDDDDDDDDDDDEDCDDDDDDDDDDDD
@8BZ
AAGAGGATGAGGAACTCTCCAACTTTGCTTACCTCTTGGCCTCTAAACTTAGCCTCTCACCAAGGGAGCATCCCCTCAGTCCTCACCATGCCTCAGGAGGT
+
8=<DBD3BF>FF+<AAEFFG>?FFE@AFC4EFFI9?BB<BFA;??DFCD9?9B<BEB>8=B3=FF<DEE2)7=B?)=@@;>@6;5=?A>B:,5:(5:(85+
@8C0
GGTCATAGAGAGCTTCCAAGTTGAGAAGTGTGTAACTGAGTATCAGGCAGGCTGCCAGGGACTGGGCACCAGGGGCAACATTTCCCTGGGTCCTGGAGAA
+
8;=BDDA;C?FFF?E>FADFAA<C@GG@CFA@?CE?EAH<?CG>G@G))06)0?B(8B(<@-.6;;()-;AB7<AA@BBB=A@C>@:@?(,5<4:?@8>?
@8C1
GCTCGAGAGTGTCGTAGAAAGAAGAAAGAATATGTGAAATGTTTAGAAAACAGAGTGGCAGTGCTTGAAAATCAAAACAAGACATTGATTGAGGAGCTAA
+
CCCFFFFFHCDADFEGHFHIJJIIHHGIGGJJIJIJIIIEIFGGIJJGIGGHIGIHIIJGI=@CDA@EHHHGADBDF;?;>@AC5;>;;@:>>C>?<?CC
@8C2
ACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGC
+
CCCFFFFFHHHHHJJJJJJIJJJJJJJJJGIJJJJJJJJJJJJJJJJIHHHJIJIJJJIIJJIJJJJHHHHHFFFFFFCEDEEDDDDDCDDDDDDDDDDDD
@8C3
CTTAGAACTTTAAGTGCAAACAGACAAACTAACAAACAAAAATTGCTTTGCTTTGCTTCAAGGTGGGGAAGACAGAAGAATTGTTAACTGAAAACAGGTG
+
+1=AA;@AC,<CBB?,+@>CBA3AB>CB<@CB<B4@1:?>B;A><*9=7**9==9*/)/><B>).5:5A/(;>))(;(.;(5-;;;5=?:(9==99,5:;
@8C4
CACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCGCCCCAAACTGGAT
+
CCCFFFFFDDFDHJJGJIIIHIGIJJIJIGIJJIGHFHJGGIJIEDFGGIJJJHIJIEIIGHHCEEFBDDEDDEDBDDDDDCDDDDDDBBD>DDDDDDDDA
@8C5
CCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTAT
+
CCCFFFFFHHHHHJJJJJJJJJJJIJJJJJJJJJHIJJJJJJJJJJJJJJIHHHFFFFFEEEEEDDDEDDDDDDDDDDDDDDDDDDEDDDDDDDDDCCDDD
@8C6
CCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATG
+
CCCFFFFFHHHFHJJIJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJIHHHFFFFBEEEEEEEDDDDDDDDDDDDDDDDDCDDDED
@8C7
TATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGG
+
CCCFFFFFHHHHGJJJJJJJJJJJJJJJJJJJJJIJJJJJIJJJJJJIJJJJJJJJJJJJHHHHHFFFDDDDDDDDDDDDDDBDDDDBDDDDDDDD9@CDD
@8C8
TTTGGAATTCTGATTTGGGAGATTTTAACTCTTGGTCATCAGCCTTATCCAGCTCATTCCAACCTTGATGTGTTAAACTATGTGCAACCGGGAGGGAGACT
+
1:14+AD;?A?<222A<A1+<3+AAF922<+111111?:*1?*00:0*****000?89DE4..-.8))=.=C=C7).)77)7.)).;)(','',3395>?4
@8C9
CTGTATGAATTGATGACTGGACAGTTACCTTATTCAAACATCAACAACAGGGACCAGATAATTTTTATGGTGGGACGAGGATACCTGTCTCCAGATCTC
+
CCCFFFFFHHHHHJJJJIJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJIHJIJJJJJJJJJJJJJJICGIHHHFDDDDCDDDDDDDDDDDDDDDED
@8CA
CTCTGTCAGTGTCTCCCATGGAGAATAATCACTGCCCAGCGTCCTCCGAGTCCCACCCGAAGCCATCCAGCCCCCGGCAGGAGAGCACACGCGTGATCC
+
C@CDFFFFHHHHHGIIIIJGI@FGGHIJJCGDHGIGHIJEFGGHCFGGEGHIJJJJIGIJHHDEEFEEECCBDD@@BBDDDBBBBDDBCDDDB>B?DED
@8CB
CACTTCCCTTGTGGGAATGTCAATTACGGCTACCAGCAACAGGGCTTGCCCTTAGAAGCCGCTACTGCCCCTGGAGCTGGTCATTACGAGGATACCATTCT
+
CCCFFFFFHHHHHIJGHIIHIIJJJJIJIJJJJJJJJJIJJJJJJJJIIJJJJFGJJIJJHHFFFEEEEDDDDDDDDDDDCCDDEEDDDDDDDDDDDDDEE
@8CC
ACCAGCAGAAGGTGAACTTTGTCCCTCCCCATCCATCCTCCATGCCTGTCACTTCCTCCAGCTTCTTTGGAGCCGCATCACAATACTGGACCTCCCCCACG
+
CCCFFFFFHHHHDHIJJIJJJHIJIJJJJJJJJJJJJJJIJJJJJJJJJJJJIJJJJJJJJJJJIJJJJIIHHHFFDDDEDDDDDDDEDDDDDDDDDDDDD
@8CD
GGAGATGTTCTTACTGGAGACTCAGGTGGAGTCATGCTTATATGGAGCAAAACTACTGTAGAGCCCACACCTGGGAAAGGACCTAAAGGTGGATATCAAAT
+
=+:A::?D8C=CD<:<E;?:3AE>AFFEEC?1:91:::CBDF@DEEDBD@0)999?B?88.==BC@C1-557=A=672;?6(.6>>;>A>A(5>A;AA5>(
@8CE
CGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCG
+
>=+22?AA;CB3<AA7AAA<A?<A9>1))88=3=3=*.>05=A;A;AA='>3>@@@>@>5;5-5;5===;9=???;9;;&88<98+883:;;3:???=:?.
@8CF
CAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGC
+
BCBFFFFFHHHHGJJJJJJIJJJJGIJJJJIJJJIJJIGIJJIJIGHIIFHIJJJIJJIJJJJIIIIJHHHHHFFFFFEEEEDDDDDDDDDDDBDDBBDDD
@8CG
CAGAAAAACAGGCCAGCTATGAACTATGATAAACTTAGCCGTTCACTCCGCTATTACTATGAGAAAGGAATTATGCAAAAGGTGGCTGGAGAGAGATATGT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJIJJIIJJIJGHGIJHHFHHFFFFFFEEEED;@BADDDADAB@BBDDEDC
@8CH
CCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACA
+
;??ABDDAH<2C?CCGHIGHGIICA<GGHEA?DD?DGGC>?DCDH@GHGFAFGGGIFGGCCH@@:=BD9>BCCACACCC<?C@CB:::A;@ACC>AAACA
@8CI
AAAGGAATTATGCAAAAGGTGGCTGGAGAGAGATATGTCTACAAGTTTGTGTGTGATCCAGAAGCCCTTTTCTCCATGGCCTTTCCAGATAATCAGCGTCC
+
BC@FFEFFHHHHHJJJJJICFGIJIJHIHIIJGGIJJIIJJJJGJGGIIFGFGCGHIJJJJIJIJJJJJHHHEHHFFFFFDEEEEEEDDDDDDDDDDDDDD
@8CJ
CTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTC
+
@@@DD8DD>DAABEF?@:CCEFEHGAE4A9<<AFFGG<4CF*::1)6@DG??DF7BFFIGH=A6=@;7@E:=>A;@DB36>;@;@;3=BC:@<::<>CAC@
@8CK
GAAAATTCATTAACAGAGATCTGGCTCATGATTCAGAAGAACTCTTTCAAGATCTAAGTCAATTACAGGAAACATGGCTTGCAGAAGCTCAGGTACCTGAC
+
@@@DDDDDHDHD>GF<A:AACBHBA:CAHIEFGHGDHDGCG;FBFDGGBF*:DGBDH@FGHGCH@GHC@FFHAFFGGE=C=?EE@D7;3;>>@.;@>CC?>
@8CL
GTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACT
+
@CCFDFF?DDDDFBAEEFHIGGIHHGGGE;FHEHDGGEGE;;FEFHGHGAGIGIEGHG3@FFGCCEICEEEHFFFCCEECECCCDDCCCCA@<CBBB@>B>
@8CM
GGGATGTTATTAACTGGAGGAGGGAAAGACAGAAAAATAATTCTGTGGGATCATGATCTGAATCCTGAAAGAGAAATAGAGGTTCCTGATCAG
+
@CCDFFEFHHGHHIIJJEHGIIJIEIJJJIJJJJJJJJJIJIIJIIJIIIJJJJJIIJJJJJJJGIIGGHEFDFFFFEEEEE@BDDDDDDDED
@8CN
GCAGGAGTACCACGACCCAGTGTATGAACACAACACCATGGTTGGCAGTGCGGCCAGCCAAAGCTTTCCCCCTCCTCTGATGATTAAACAGGAACCCAG
+
CCCFFFFDHHHGHIJJJJJJHHHJJJIIJJJJIJJJJJJJJDHIJJJJHIIJJHHFFFDEEEDDDDDDDDDDDDDDDCDDEDDEEEDDDDDDDDDDDDD
@8CO
ACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTAAGGCCTGCCTTGGAGAGATTTTTGGGTCGTTCTGGCTAGG
+
@@@DDFFFAHHHFGHGGIEHIGIIIDHIIIGIIGECHHIGEE?@DFBCFAGGIIGBHAEEEEHHFFFDEEE>A@-;;=@D>CDD@@B?C<BBDBCCA348<
@8CP
GAAGACCTTGGTGATTTAAGGCGGCAGGTTAAACTCTTAGAAGAGAAGAATACCATGTATATGCAGAATACTGTCAGTCTAGAGGAAGAGTTAAGAAAGGC
+
CCCFFFFFHHHCFHIJJIJJJJJJGBHIBFHIJIJJJJJJIJJIGHIEHIJJHHHHHHHFEFFFFFDEEEEDEEDDDCDDDDDDDDDDDD@CCDDDDDCBD
@8CQ
AGGCCATGTTGCAGCTGACCACCCACCTGCAGTGTACCGCCGGAAGCACCAGGAGCTGCAAGCCATGCAGATGGAGCTGCAGAGCCCTGAGTACAAGCTG
+
CCCFFFFFHHHHHIJJJIJJJJJJJJJJJJIIGHHIIIIJJGIJJJIJJHHHHFFFFEDEEEDDDDDDDDDDDDCDDDDDDDDDDDDDDDDCDDDDDDDD
@8CR
CCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCGCAGGAT
+
@@CFBDD=FHDDHIGGIJIGIJIJIJIEIHIHGHJGIJJJIGGGIIHIJJFDIHIIJIHGIGFHJJIIDHHGFEDFECCCECCDCCCCDDCCDDDDBDDBC
@8CS
AAGGAACTCACCAGGATTTCCGCAGTAACGGCGGATGCGAACGGCACCGTCAGCTACTTGGCTGCCACAAAGTTCGGGGATGACATCTCCTGAGTCTCAC
+
(((-@.())<)@@@@@1.).)(<?((.@)((:('-5'.'-5,'''3',','+)(5(+((+((((+((+((8(((((&&0&&2(8+(8(+(8((((((+(+
@8CT
TGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGC
+
CCCFFFFFHHHHHJJJIJJJJJJJJJJJIIJJJJJJJJJJJIJIJJIJJJJGIJJJIJJJJIJJJHHHGHGFFF>CFEEDEEDDDDDDDDDDDDDDDDDD
@8CU
CTGGAAATGATGCCTATGTTGACATTGATCGATAGCTGAAAAAACCTACAGATGATCTAAATTAAGCTTTATCAGCAAAGGAAGAAATTGCTCAAGGATGC
+
===?AAA+2<,22ACBB=,,@AC+3?AC7A;++:)@**:**1)80=*=*9*9))/)9)))>A)>B)).=7)=7>7.).).;>;>>@;5((55;;5((59>2
@8CV
CCTGTCTCCAGATCTCAGTAAGGTACGGAGTAACTGTCCAAAAGCCATGAAGAGATTAATGGCAGAGTGCCTCAAAAAGAAAAGAGATGAGAGACCACTCT
+
@C@FFFFFHHGHHJJJJIIJJJJFHHIJJJHHIJJJIGHJJJJJJJIIGGIGIEDGHIIJGIIJIIF@EHIFHHHHGFFFEEEEDCCCCDDC:?CBDDDDD
@8CW
CCTACACCTCAGCAGTTACAAGCCTTCAAAAATGAAGTAGGAGTACTCAGGAAAACACGACATGTGAATATCCTACTCTTCATGGGCTATTCCACAAAGCC
+
@@@DFDBBHDHHFGBHGIHIEGCGBBFBFEHIII<DFFBFCHEDGD??>GHEHADGBCFEGHBHGIGFHHHHHFFFFEDCCECEEBD=?CCD@CCCDDCD?
@8CX
TACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGC
+
CCCFFFFFHGHHHJJJJIJJJJJIIJJJJJIJJJJJJJJJJJGIIJJJJJIJJJJJJJJJJJJJGIIGHHHFFFFFFEEDDDDBBDDDDDDDDDDCDCDD
@8CY
CTTCATGTTCCAGTGCCTCGAGCGCTCAGGATGGAGGAAGACTCGATCCGCCTGCCTGCGCACCTGCGCTTGCAGCCAATTTACTGGAGCAGGGATGACGT
+
?@?BD??D?ADDFGBDA:A<3?@?CGEGHIEHEC30BBGBBHDHEE3=C=CAH?C9AA2?D6>BC?B@BB??BCCAB2?(>A>>:@:32<2?852<?C>@?
@8CZ
CAGCAGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGG
+
CCCFFFFFHHHHHJJJIIJIIIJJJJJJJJIGGGJJJIJJIJJJJJJJIIIJIJIGHHGHHHFFFFFEEDDDEEDDDDD9@BDDDDDDDDDDDBBDDDCC
@8D0
CTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGC
+
CCCFFFFFHGGHHJJIJJJJIJJJJJJJJJIJIJGIJJJHIIJJIIJJJGIGIJJJJHIIIIIGGHGGHHHHFFFFEEEECDDDDDDDBCBDDDDDDDDDD
@8D1
GCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGG
+
CCCFFFFFGHHHHJJIIJJJJJIJIJJCHGHJIIJJJJIIEGHHJJJJJJJGJFFHFBCEDDEECDDEEDDD>CDDEDDDCCCCCDDDDDDD>CCDDDDD
@8D2
GACGGTTTCGCCGGCAGTCTCGATGATAGTATTTCTGCTGCAAGTACTTCTGATGTTCAAGATCGCCTGTCAGCTCTTGAGTCACGAGTTCAGCAACA
+
?;?DD:D8CCDDDEEIIBDEAD*B@?BDE9?DDEIADDDB=CCE@AEEIEDIE>CDC;ACC@C;=@<<@>>;6>AAAA>AAAAA>???<>>DAAA?<1
@8D3
GTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGC
+
C@@FFFFFHHHHHJJJJJJJJJJJIIIJJJJJIJJIJIJJJJJJJJJJIJJIJJJJJJJJJJHHHHFFFFFEEEEECDEDEEDEDDDDDDDDDDDDDDDDD
@8D4
CCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTTTATGGGCAGGAGT
+
@@CDFFDFHGBHCGHIJIIIJIJJIHGIJJJJIIJJJJIGIJGHIIJGIIJFGHJGIJJJJHHFFFFDDDDDDDD@CCDDECDD:<BBDDDDDDDDDD@BA
@8D5
CCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGC
+
CCCFFFEFHHHHHJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJIJJJJJJJJJHHHHHHFFFFFFEEEDDDDDDDDDEEEDDEDEDDDD
@8D6
TGACCCCCTGAAGGTGTACCCGCCACTGAAGGGGAGCTTCCCGGAGAACCTGAGACACCTTAAGAACACCATGGAGACCATAGACTGGAAGGTCTTTG
+
CCCFFFFFHHHHHJFGHJJJJJJJJJJJJJJJJJJJJJJJJJJJIJHHHHFFFFFEEEDEDDDDDDDDDDDDDDDDDDDDDDD:@CDDDDDD3@CDDD
@8D7
TACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAAC
+
8=??AAB2=AD<C?DB?AA:33A+A<1C?C<8BD@D>?D>9BDEA?.=8BD4@ADD9>;5;>;@;AAA255(;A;:5<:<=9=<92<<<<A>A>><?(8>
@8D8
GAAAAACAGAGAAGCTGCTCGAGAATGTCGCAGAAAGAAGAAAGAATATGTGAAATGCCTGGAAAACCGAGTTGCAGTCCTGGAAAATCAAAATAAAACTC
+
@@@DDDADHFDFFFI@AE9AFHEIGGEECHBCGHGICB?BGHGG*BFHHI8@FHGGFHEGHIIEEFFEECA;=CCCC@ACCCCBCCCCCCCCCCCCCC>CC
@8D9
CAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATAC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJIIJJIJJJJJJIJJIJJJJJGJJIGGGGJIHHHHFFFFECEEEEEEDDDDDDDDDDDDDDDDDDDDDDDD
@8DA
CGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCA
+
?@+AD@D>HDFFHD?F;CFHEEH@FHHEGGFDGGIGEIIGIIIAHIGGIIHHEEHHFHCE4>A:?BB?BBBBCAC;:@DCCCCC?@B<<B??B@BBBCC
@8DB
CTCCAACTTTGCTTACCTCTTGGCCTCTAAACTTAGCCTCTCACCAAGGGAGCATCCCCTCAGTCCTCACCATGCCTCAGGAGGTCAGGGCAGCCAGAG
+
CCCFFFFFHGHHHJIIIJJJJIJIIJJJIIIJJJJJFIIIJJJJJIJIJJJJJJJJJJJIIJJJJJIJEHHHHFFFFFEEEACD;CCDDDBBBBBDBBD
@8DC
CCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTAT
+
@@@?DDDDFFHDFGGGHI>CFGEHII?FGIIGGIEGHFGG<8DHBEB4@ECAHHEEEEDCC@ACACCDCCCCBBCBBBBBB8?:CACCBB98<ABBCCCCC
@8DD
CTGGGCTTCAGGGGGCTGGGGGCGCCGCTTGCCTTGGAAAGGTTTCTTCTTCAGGAAAACGGGCAAGAGAAGTGCATGGTGGGCAGGAGCAAGCCCT
+
???BDAADFHHB;@?:8EHEDGHIBHB699;A?;@@;;,559C@:>@CCC3@99::2>C958<5>B@CBCC?AAA:AAB:@@B?<>BBBBBC?8?8A
@8DE
GCCAAACATCCCCTTCCCACCACAAGGCTTTAAGCAGGAGTACCACGACCCAGTGTATGAACACAACCCCATGGTTGGCAGTGCGGCCAGCCAAAGCTTTC
+
;7;?ABDD8<+AD9:;EE+:)AAF;?)@?93?:?@9)?)?99B***?6@8'=CE<@=C:>7A)=.,?(,=>35>AA1/3:5<((0099)8<<<<?<3(+43
@8DF
GGACAGCAGATACTTGTGCCCAGCAATCAGGTGGTCGTACAAACTGCATCAGGAGATATGCAAACATATCAGATCCGAACTACACCTTCAGCTACTTCTCT
+
@CCFFFFFHFHHHIIGGGHIIGGIGHHHGIIDGGFIIHGHIIGHIIGGIIJICHCAF@FHGHGIIHIFGHEAHDFFBABBA@CCCCDDCCCCDACCDDDDC
@8DG
GAACAGAGCTGTGAAACCGTAGGGCATCCCAGTGATCTGTGGGCAGAAGGTTGCTTCCCATTGCTAGAAAGTGGTGATTCCACACTGGGGTCTTCCAA
+
@C@FFDADHDAADBFIIHIGGGIIIEIIGIIIIEIIIIIIGGIIIIIGA@BFGGHIIIIIIIIHIHHGCC>7;@7?;>@@ECCEBDAA@B8=ACDDDD
@8DH
TTCAAATATTACAGTTAATGAAGATCAGATAAAGTTAATGAATGTGGCAATAAATGAACTGAATATAAAATTGCAAGATACTAACTCTCAAAAGGAAAAAC
+
CCCFFFFFHHHHHJJJJJIJHHIIIIJIJJIJJJHHIJJJJJJJCHGIIJIJJJJJJJJJJIJGHIIJIIJJJIIJIFIGIIJJEHGGHHHFFFFEEEEED
@8DI
CTCCGTTATTACTATGATAAAAACATTATGACCAAAGTGCACGGCAAAAGATATGCTTACAAATTTGACTTCCACGGCATTGCCCAGGCTCTGCAGCCAC
+
CCCFFDFFHHHHHJJJJIJJJJIJJJIIJIJJJIJIJGHIJJJJIJJJJIJIEGHGIGGJJIIIJJJJJHGHHHHEFDDDDDDDDDDDDDDDDDDDDDDD
@8DJ
CACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGAC
+
@@@DDFFFGHHHFBDGEBFGHCHGEHIJGGGCDDDFHEHEGGGFGGIJGGHCAGHGC:CGF@CEGGIB>>ECBEBAAA@CDDBD@BDCDC@CDDDDDCC?C
@8DK
CTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAAC
+
C@@FFDDDHFHGHGBBGIIG<EEHHIIIIIICGGGI>FHIFHECFGHDHIIIC=DDEGGHFHD@>?BCCCAB?ABBCBBBBCC?CCCACCCCCCB9>>>CC
@8DL
GAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACC
+
@@@DDD?;DH?HDGGEEEGGEGHF?CCFHEHHBAFBBDEGEAHHDBGEBHGECEHD@BDECCCDCCCCCCB?BB@BBBBBBBCCCCC?>@::A@AA<CAB
@8DM
CGAGACATCTACAGGGCGAGCTACTATAGAAAGCGAGGCTGTGCCATGCTGCCAGATAAGTGGATGCCCCCAGAGGCCTTCATGGAAGGAAAATTCACTTC
+
+11@+<+?=@?>=C+2?0))4)?1*11:4=?4:*))('452==>>=)=)=A3())().77((.(652(,(;:(55;1((38888(4(((2;(83((3(+3(
@8DN
CACATCAACGAGGAGGACACAGTGCCTCTTTCTCACTTTGATGAGAGCATGGCCTACATGCCGGAAGGGGGCTGCTGCAACCCCCACCCCTACAACGAAGG
+
CCCFFFFFHHFAFEHGGIICHHAFHIIGGGIGHIGIHGII?BFH>BDDH3FEDHAFGGAH@EHHDDDDDDD?@B?ACCDDABBB39>BDD?BDDDD@@@DD
@8DO
CAGCTATGGAGAAAAGTGCCTGTACAATGTCAGTGCCTATGATCAGAAGCCACAAGTGGGAATGAGGCCCTCCAACCCCCCCACACCATCCAGCACGCC
+
CCCFFFFFHHHHHJJJGHJJJJHJJJJJJJJJJGIJJJJJJJJJJJJIJJJJJJJJHHIJIJIJJJJIJJJJHHHHHFFDDDDDDDDDDDDDDDDD@DD
@8DP
CGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCG
+
=;1++<)?A+27<AA>ACA84?=1?;<>A251=A;93.><';=;BAAA=@@@;>>>@@@;-;;5;==9(:99>??==55-9989<<=;:=33:???==??&
@8DQ
GAAAGATTGATTTTCTTAGACTCCATTAAGTCCAAATCCAAAGACTCTGTGTGGGAAAAAGAAATAGAAATACTTATAGAGGAAAATGAGGACCTCAAAC
+
CCCFFFFFHHHHHJIJJJJJJJJJIIJJJJHIIIJJJJJJJIJIIJIIJHIEGGIGIJIJIJJIGIEIIIGIIIIFHGHHHFFFFFDEDDECBBDDDDDD
@8DR
GTTATTAACTGGAGGAGGGAAAGACAGAAAAATAATTCTGTGGGATCATGATCTGAATCCTGAAAGAGAAATAGAGGTTCCTGATCAGTATGGCACAATC
+
@@BFFFFFHHHGDHIEHIIHIJJJJJJJJJIJIJJJJJJJHIIJIIJJJJIJJJJJIJEGHJIJJJJHGHGHFFFFFEDEEDECDDEDDDFEDDDDDDDD
@8DS
GGAGACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTT
+
8??:BDA@0@@<?EBBEEDC>EDDDDDDI?BB9DBBCCAD>DCAA::'?>D@@>?A:555;:>A>>A;,::=8(::99>A>;999>??>?8<3>:(:::>
@8DT
CAGAGGGAGGCCGAGCTGCTCACCAACCTGCAGCATGAGCACATTGTCAAGTTCTATGGAGTGTGCGGCGATGGGGACCCCCTCATCATGGTCTTTGAAT
+
CCCFFFFFDFHHGJDGGHGFIJIJJJJIJJJIJJIIJJJJIJJJJJGIFHHEEGGHIJHAHAHFFFFDDDDDBDDDBBBDDDDDDCCCDDDACCDDDDDD
@8DU
CAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGC
+
CCCFDFFFHHHGFIIJJJJJJJJJJJJJJJJIJJGIJJJJJJJJJJJJJIJJJJIJJJJJJJJJJJHHHHHHFFFFFFDDDDDDDDDEEDDDEDEDDDD
@8DV
CCTCCATGCCTGTCACTTCCTCCAGCTTCTTTGGAGCCGCATCACAATACTGGACCTCCCCCACGGGGGGAATCTACCCCAACCCCAACGTCCCCCGCCAT
+
@@@FFFFFGHHHHBAGGIJIIIJGIGIJIIIIJJHIGIIGIIGGGIJJHI@HIIIGIJJIGIFHFFDCDDB@BCDDDDBDBB?BDD@BBDDBDDDD>BDDD
@8DW
CCTGGCTTACATGAACCACATCATGGTCTCTGTCTCCCCGCCTGAAGAGCACGCCATGCCCATTGGGAGAATAGCAGATGTGCAGCACATTAAGAGG
+
@@@?DBDDFFDHB>EHGGGG@E:CHGDH@FGEFH>GHG?@GGHHGCGIGBGCHDHI1@DH@AEHHEEDE>>C@CCCACCCACCCCCBBCCCCCCCCB
@8DX
CGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTAT
+
C@CFFFFFHGHHHJIJJIIJJJJIJJIIJJIIJJJJJIIIHIJIJHHIJJIIJJJ<DFFFFFDDCBDDDDDDDDDDDCCCDDDDDDCD@CDDECCDDCDDC
@8DY
GGGACACTTGGGAGTGGAGAGGAGAGGGTCTGGGAAGGTTATAAACCAGGTATCTCTACATCAGGATGGCCATCTAGGAGGCGCTGGGACTCCTGGGCACT
+
981@3((2.4?1((2.(=3.3=(-(<5--:1.737171=1<)6=33:17(.).:8.)=8;3>>;8>;?/0.).(666(6955'32&0+(+22:/3(26262
@8DZ
GGACAAGTGCAAGCCTATGTTCTATGAGGAGAAGCGGCAGCTCAGCTTGGACATCAACAAGCTCCCCGGCGAGAAGCTGGGCCGCGTGGTGCACATCATCC
+
;815=11.<?)2>39:9<>9):;@>;?9?;9183@88=4=9?<<33=3:=36:8>?8=3:)66=;??=<<'8585</+2852858:&85((+8:<:;:::;
@8E0
CCGCTATTACTATGAGAAAGGAATTATGCAAAAGGTGGCTGGAGAGAGATATGTCTACAAGTTTGTGTGCGATCCAGAAGCCCTTTTCTCCATGGCCTTTC
+
CC@FFFFFHHHHHJJICFHEIJIGGIGFGIJIIIJCGHDBGHEHIGEHDHBFGHIHAGADC@FGIGHCH):=EBBEDEEDCBDDCDDC<ACCD@ABCACCC
@8E1
CACACCATGATTTGAATATTGATCAATCACAGTGTAATGAAATGTACATAAATAGTTCTCAGAGAGTAGAATCAACTGTGATTCCTGAATCTACAATAATG
+
CCCFFFFFHHHHHIJJJJJIGIGJJJJIJJIJJJGIJJJJJJJJBGIJJIJIIJIIJIJHJJJGIIDGGJIJJJIIJIGGIIJJJJHHHHGHFFFFFFEEC
@8E2
GGAGATGTTCTTACTGGAGACTCAGGTGGAGTCATGCTTATATGGAGCAAAACTACTGTAGAGCCCACACCTGGGAAAGGACCTAAAGGGGTATATCAAAT
+
??@FDDDFFFAHBFGH<D;BCEHIGGEDEHB1:E@GGEG?DAFG?BFEHH>?BF</?DGH>BFHIB2C=EE.=AE2;?;?2>;;-;;CC(83/5>@AAA>;
@8E3
CGAGGATACCTGTCTCCAGATCTCAGTAAGGTACGGAGTAACTGTCCAAAAGCCATGAAGAGATTAATGGCAGAGTGCCTCAAAAAGAAAAGAGATGAG
+
@@CFFDFDDHHGHIIIIJJGHGHICHHIIEGCFHIEBEDGGIGIGGIJJJJ@CHDHCGIHJHIGIJGGGECEEEE??CF7BCEEEDBBBDDDDCCDCDC
@8E4
CAAGTTTCATACTTACTATTATAGTTGGAATATTTCTGGTTGTTACAATCCCACTGACCTTTGTCTGGCATAGAAGATTAAAGAATCAAAAAAGTGCCA
+
@@@DD8DD>DDH?EDHIIIIHGC@?IEF>AF@AFH<FHIHGIEFHHHGEFIIG@DGHEGDEGHFGHFHAG@FCA;E)=@GI;E3=EDDDCDFB?CA:>;
@8E5
GACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCCACAC
+
CCCFFFFFHHHHHJJJJJJIJJJJJJJ@FHIIJJJIJIIJJJJJJJJJJJIJJJIJJJJJJIJJJJJJHHHHHFFFFFDEEEDDDDDDDDEEDDDDDDD
@8E6
CTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTAC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJIIJJJJJJJJJJJJJJJJHHHHHHFFFFFFDDECEDDEDDDDEDDEDDDDDDDCCDDDDDDBDDDDD
@8E7
ATTCTTCCACCCTGGAAACTCTATACACACACAGCCGGAGGTCATACTGCATCAGAACCATGAAGAAGATAACTGTGTCCAGAGGACCCCCAGGCCATCCG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJIJJJJJJJJJJHGIIGGIJJJJJJJJJJJJJJHHHHHFFFFFDEEEEEEDDDDDDDDDDDDDDDDBDDDDDDDDD
@8E8
GACTATGACAAGCAGGGGTGCTGAAGGATCAGTTTCTAAAGTAAATAAAAGTTTTGGTGAAGAATCAAAAATAATGGTGGAAGATAAAGTTTCTTTTGAA
+
CCCFFFFFHGHGHIHJJGCEHHIJIGIJJJIIJJIGGIIJIGGHGJIJJIJFHIIJGFDHJGJJJJHFHHHFFFFFF>CCDECDCDDDDDCDDDDDDCBC
@8E9
CAACGCCAGATGTCTGAGCCAAACATCCCCTTCCCACCACAAGGCTTTAAGCAGGAGTACCACGACCCAGTGTATGAACACAACACCATGGTTGGCAGTGC
+
@C@DFDFFHFDDFBEGGD<FDGDGHHIAFGIIIIIIIIEHGDABFCEGGGGAHHIGG@CE>CEEDFCCBBAC>BDDCDCCCCBB@BBCCCCCCB@CCBCC@
@8EA
TCACGACAAATCACCGGCCTTCTCCTGACCCCGAGCAGCGGCCCCTCCGGTCCCCCCTGGACAACATGATCCGCCGCCTCTCCCCGGCTGAGAGAGCTC
+
@@@FFFFDFDDFHIIIDHGGHIJIIIGIIIGHGIEIJGGHIHGFFBACD>>BDDDDDDDBD?CDD@?@CCCD@BD>@@@BCDDDDB<@@@BB@AB?ACC
@8EB
GAAAAAAGAAAAGCACAAAAGGAAAGAGGAAGTGGAAGAGAATAAAAAAAGCAAAGCCAAGGAACCTCCTCCTAAAAAGACGAAGAAAAATAATAGCAGC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJIGGIIBGHIIIIIJJGHJJJJJJHHHHFFFFFEDDEDDDDDDDDDDDDDDDDDDDDDBDDDDD@DDDDCDDDD
@8EC
GAAAAATAATAGCAGCAACAGCAATGTGAGCAAGAAGGAGCCAGCGCCCATGAAGAGCAAGCCCCCTCCCACGTATGAGTCGGAGGAAGAGGACAAGTGC
+
CCCFFFFFHHHHHJJJJJJJJJJJIJHIIJJJJJJJJJJJJJJJJJJJJJJJIJJJJIIJHGHHFFDDDDDDDACDDDDCDDD@BDDDDDDDB?CDDACC
@8ED
TATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCCAAACTGGATCCTACAGCCAAGCTCCAAGTC
+
@@?DADF?DDFFHIIIIIDGFGEAFFEGIIG:?F3D>GEGE9FG<G<8B2?FG?HADGF@>@FHDHCEAD>BCA?@CCCACCCCCCCAAACA@CC:@C@CC
@8EE
CTTTTGAGCGTGGAGTAGGATGCCTGGATTTTTCAAAAGCAGATTCAGGTGTTCATTTATGTGTTATTGATGACTCCAATGAGCATATGCTTACTGTATGG
+
<?8?;DDDFF:DDCGACCHA4ABFIIF>FFI@BC@D>B@DFBDEFDDFF/9.<<F=CF@CC=@7=E>AC==CEFEEED<@D>;A:;;@A(5@@BBBDBDBB
@8EF
AACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJIIIIIJJJJJJJJJJJJJJJJJDGIIIJJJIJJJJJJJJHHHHHFFFFEEEDEEEDDDDDDDDDDDDDDDDDDD
@8EG
CCCTGAAGAATTCCAACCCCGACGAGATTGAAATCGACTTTGAGACCCTGAAGCCGTCCACACTGCGTGAGCTGGAGCGCTATGTCACCTCCTGTTTGCGG
+
C@@DFFDDHHHHHIIIIIIFEG@<FGIIIGAHGGIIHHBAHHBGIIIII;EH>?ABDBAB@>5;5@@@@@B>CCD?BA5-299:CDC@CC@BC>>ACCCBB
@8EH
AGCCACTGCACCTACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATG
+
CCCFFFFFHHHHHJJJJIJJJJIJJJJJJJJJJJJJJIJJJJJJJJIJJJJIIIJJJJHHHHHFFFFFFEEDDDDBBDDDDDDDBBDDDDDDDDDDCDDDD
@8EI
GGAAGCTGTACTGTCCCACCTAACGTTGCAACTGGGAGACTTCCGGGGGCCTCACTGCTCCTAGAGCCCTCTTCGCTGACTGCCAATATGAAGGAGGTACC
+
CCCFFFFFHHHHHJJJJJJJJJIHHEHJIJJJJJJJJJJIJIJJJJJJFDDDDDDDDDDDDDDDDDDDBDDDDDBDDDDDDDDDDDDCCDDDDDBBD<CDC
@8EJ
AATGAGCATATGCTTACTGTATGGGACTGGCAGAGGAAAGCAAAAGGAGCAGAAATAAAGACAACAAATGAAGTTGTTTTGGCTGTGGAGTTTCACCCAAC
+
CCCFFDFFHHDHHJJJGIJIDJHGGIJJJIGGIGIGIIJJIJJJIJIGIJIIIJJGIJJIJJGIIJIHEGEHHFFFFFEDDDDDDACD@ACCDEDDDDDDD
@8EK
AGAAAATGTACAGTCATGTGATACTCAAGTAAGCTCTTTATTAGATGGAGTTGTGACTATGACAAGCAGGGGTGCTGAAGGATCAGTTTCTAAAGTAAAT
+
??1B:+A?A?DDD4CD9E:CBAE??<FCEIAEFEICFEEAEDEFD@DDEA9?B9??D?D<DD<DEDDCD@@@;=D@C;;@>?;>>A;>ADAEEAA>;;5>
@8EL
ACATGCCAAGGCAATCTCCTTATCATGGGGACTGAGGATGCCTCCTCCTTGCCTGAAGCCAGTCAAGAGGCAGGGAGCAGAGGCAATTCCTTTTCTCCTCT
+
????:::==;FBB:?F<A?FFEHHB@HFH=1???9??9?BDG<?B?BFDGIG;4==<8.(==DG@AC7==(;;8>19/,,(9<@?9:5:>5::4++:4((+
@8EM
AAAAGAAGGAGAGAAAGAATGGGATGTCTTGGAATATGTGGAAGATGATGAAAAAAGGGTCGATGGAATAGGTACAAAAATAAGAATGATAGGGGGGGGG
+
(---((2).((((-))))().)(22())2:))1)).))0))).:())))))0.9('5((()''-)'))(.(...((--((,((((,,(((7(,()&&&&)
@8EN
AACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHIJJJJJJJHHHHFFFFEEEEEDDDDDDDDDDDDDDDEDDDDEDDEDDDDDDD@CDD
@8EO
TGTTACTCTATCCACACTGCAGATTATTGGACTTGGCACTTTTGAGCGTGGAGTAGGATGCCTGGATTTTTCAAAAGCAGATTCAGGTGTTCATTTATGTG
+
?@??ABD?CFBFFBGI=AI>?B+<<CE@4A?E?CGFFIBDFFEFEFF?GFF(==CBFECFEFA;9EEE>EEFFFDBBB;@>@AA;@;-;;?BA>BD@B:,;
@8EP
CGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGG
+
CCCFFFFFHHHHFJIJJGJHIJJJJJJJJIIIIJIJJJJJJIJJJJJJJJJJJJJI>HHFFFEDABDADDDDDDDDCDDEDDDDDDDDDDDDDDDDCDEDD
@8EQ
AGTGGATGCCCCCAGAGGCCTTCATGGAAGGAATATTCACTTCTAAAACAGACACATGGTCCTTTGGAGTGCTGCTATGGGAAATCTTTTCTCTTGGATAT
+
BCBFFFFFHHHHHJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJHHEEHFFFFFFEDEEEDDDDDDDDDDDDDDDDED
@8ER
AAACTCCGGGTCACAGAAGTAAGTAGGACCAAGACCCCTGGACCTGGGGCCCAGTAGGCAATCAGAGGCCTTGCCGGCGCGGGTATGAAAAGCAGGCGG
+
0(0-(..-8(((.)2;)@)))2)):2)2)8(((:<).5(-(<7)0;75''''(())8=))..93=((,(((((-4'''&&&0&5-85(3(+(((++-&5
@8ES
CTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCC
+
CCCFFFFFHGHHHIJJJJHJFIJJJIGJGIJJJIIJJJJJJJJJJJIJJIJIJIIIIIJJIHHHHHFFFFFDEEEEDBBDDDDDDDDDDDDDEECDDDDDD
@8ET
TGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTG
+
CC@FFDFFHHHHHJJJJJJJIJJJJIJJJIJJJJJJJJJJGJJIIIJIJJJJJJIJJJJJHHHHHGFFFFDEDDDEDDDDDDDDCDCDEDEDDCDDDDDDC
@8EU
CAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJIJJJJJJJHHHHFFFFEEEECEEDEEDEDDDDDDBDDDDCCDDDDC
@8EV
CTGACCACTTTGGCAGATGAAGCTCAGTCTCTGAAAGATGAGATCGACGTGCTGAGACATTCTTCTGATAAAGTATCTAAACTAGAAGGTCAAGTAGAATC
+
CCCFFFFFHHHHHJIJJIJJJJJIJJIGJJJJJJIJJGIJIIJIJJJJJEIJJJIIJJJJJJJJJIJGHGHHHHFFFEFFFEEECEDDDDDDDDDCCDDDD
@8EW
GGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTC
+
CC@DFFFFHHHHHJIJIJFJIJJJJIJJJIJJJJHGIJJJJDHIJIHIIJIIIJJJJJJIJIJJIJJIGHHEHBFFFFFDEEECBDDCDDCCBCDCDDEDD
@8EX
CCTCCTCTGGCAAGGCTGCAAAGAAACCCACAGCTGCAGAGATCTCTGTTCGAGTCCCTAGAGGGCCGGCCGTGGAAGGGGGACACGTGAATATGGCATTC
+
=;1B;3AD?C2CDBBBE@+CE>EEB>BB?EDACD<BDDC?B)?B?DDE8?DDCB=A@C@CDDCAA<;?<???=???AA??>>-9(2;8(+<>A:3383>::
@8EY
GAGAAAGGAATTATGCAAAAGGTGGCTGGAGAGAGATATGTCTACAAGTTTGTGTGTGATCCAGAAGCCCTTTTCTCCATGGCCTTTCCAGATAATCAGCG
+
???DDBA>DHAHD@HIIGEHEHAFHIIIIIICF8CBA4:DFG<D@FIEHHIG;?=B(=FCFA@GEHGGGH>EE??DFDD@CC@EEDCDDC>3>,:@A::A;
@8EZ
TCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATG
+
CCCFFFFFHHHGHJJJJJJJJJJJFIJJJJJIJJJIIJJJFHIJJJJJJJJEHHHHHFFFFFFEEEDDDDDDDDDDDFDCDDDDDDDDDDDDDDCBDDDDD
@8F0
CCAAGAAGAAACATTCAGACTAGAAGCAGCCAAAGATGATTATCGAATACGTTGTGAAGAGTTAGAAAAGGAGATCTCTGAACTTCGGCAACAGAATGATG
+
@@@FFFFFHHHHGJIJIIJJJJJJJCIIIJIJJJJFIIJJJIIJGGJEHIJHGIAHIJJJJFCGGIJJJJJHFHHFFFFFFFEEEEDBDDDDDDDDDDDDC
@8F1
CTTGTGCCCAGCAATCAGGTGGTCGTACAAACTGCATCAGGAGATATGCAAACATATCAGATCCGAACTACACCTTCAGCTACTTCTCTGCCACAAACTGT
+
CCCFFFFFHHHHHJJJJJJIHIHIJIJJJJJJJJJJJJJJIJJIJJJJJJJJIJJJJJJJJJJJJJHHHFFFFFDEEEEEDDDDDDDDDDDDDDDDDDDDC
@8F2
CTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGC
+
CC@DFABDFHHHAEHG???FBFFGGD7FHGE@DFHH@HIEGE;FFBBGIADFHGFH;=CF@AEGI=CE@>@@777;@>C;>>AC>BBB<ACCCCBCBA@A
@8F3
CAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCA
+
CCCFFFFFGHHHHJIJJIHHIGIHIJJHGIJJJJJHIIJIIIIJJIJJJIIJJJJIJJJJJJJIJIJIHGHHFFDDEDEDDDDDDDDDDCDDDDDBCDDD
@8F4
GTGAGATTAGTTTTCTAAATGAAGAAGTTAAATCTTTAAAGCAAGAGAAAGAACAAGTTTCATTGAGATGTAGAGAGCTAGAAATCATTATTAACCACAAC
+
@?@DFBEFHHHHHJIIJIJJIHJIJJJHHIIJIIJIJIJIJIIIJJJJJJHIJIIIIIJJIGIIJJJIJIEGGGIIIJJIHHHHFFFFFFFFFEEEEDDD@
@8F5
CCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCC
+
CCCFFFFFHHHHHIJJJJJJJIJJJJJJJJJIIJDHIJJJJJJJJJJIIJJGIJJJJJJJJIHHHFFFFFEEDDDDDDDDEEDDDDDDDDDDDDDDDDCDD
@8F6
ATGACACCTGTGTTGTCCCAGAAAAATTCGATGGAGACATCAAACAAGAGCCAGGAATGTATCGGGAAGGACCCACATACCAACGGCGAGGATCACTTC
+
@@<BDDFFDGCFHII@EEDHGIIGHGEGH@C>F8CDHHGGGGEGGIIGEGIGIIHCHCD=@8@;@B>BB?BCA?2;@>CCCCC<5;5<>>@@398>4>A
@8F7
CTTCAGAAGAGAAATCATAAAGACAGCCAGTTCGAAACTGATATAGTACAACGAATGGAACAAGAAACACAAAGAAAGTTAGAACAACTCCGGGCAGAGCT
+
?<<B;?;DCA3DD?E<?CEA<DHGF:8ACEG9CC?FF:GD*0?B*0???*9B67;8B)8C9(=;@EB7?ECEB);BC;ACD3;;>A?BA>C(8'85)8<C(
@8F8
CATGGGGTTGTAGGGAAAGAGTGTAGATCTCTGTGGTCGCAGTATCATTAAATAAAAAAAACAAAGCTATGGAACCAATGGAAAGCCCACTGATGTCAGC
+
===+?<+<<)0,<>7<ABB9A7>:==A<?41**??;0?00)(/=*?)7)))//=7)))-,=,;==35(5-5((((,(5(:93+8(+(8;8988;3;=(+8
@8F9
CCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGT
+
@@@FFFFFHHHHGIIIGJIJFGHIIJJJJIIGIJGIIJGIIGEHIDCDGGFIHEEHFFFFCFFFEEEDEDCBD>CDDCCDDBBBBDCDDDDDDDDDDDDDD
@8FA
CCAGTTGCTCAACTGGTCCCCATTGTGCCCCTGGAAAAAGCTTGGCCAGGGCCACATGGGACAACCGGGGAAGGAGGTCCTGGGGCCACTCTATCCAAGCC
+
@@@=:A4+A<D<F?3A:??DGG>FCBC+<9AD=;BGGGI<3B>;?D@GG=:BD1@9C:@D=@1=CCDD<?;8?82902<::@(89<<<BA?@C>AC(4:@B
@8FB
CTCAAGTAAGCTCTTTATTAGATGGAGTTGTGACTATGACAAGCAGGGGTGCTGAAGGATCAGTTTCTAAAGTAAATAAAAGTTTTGGTGAAGAATCAAA
+
@@@DAFDDFHGHHJIGIIIJIIIEHEG@DDEHEDDGHHIIJDHIHIJII6@BGGDGGIIJIIJIHHEGHHHHAEHFDFFFFDEDEDED(;CDCDDDCDDC
@8FC
CTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGC
+
CCCFFFFFHHHHGJGIJJJJJJJJJIJIJIJJJIJJJJJJJIIJJIJJIJIIJJJJIJJJJJIJJGHHHFFFEFFDDEECEEDDDDDDDBDDDDDDDDDD
@8FD
TAACGTGAAAGCCTTACAGAAATCTCCAGGACCTCAGCGAGAAAGGAAGTCATCTTCATCCTCAGAAGACAGGAATCGAATGAAAACACTTGGTAGACGGG
+
+:?DDBBDDHDBD>GDCFE<GHA<FEECFHGHD@BDHEG<AFHIBGFHCF@BGHC;FGG;77=EECHE3?ECD@BC@A;@>?CACCCBBCC>@55:@>>B@
@8FE
CAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGAGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJIJJJJJJJJJJJJIJJJJJJJJI*BGGJJJJIIJHHHHFFFFFFEDDEDDDCDDDDEDDDCDDDDDDD?CCDDD
@8FF
GACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTG
+
@@@D=D?DDFD<FBHEHBB;FEHHEE?@<GDG@HECDBGGCBAFF>FBBAGEFFG>E>CEEAEEBC>@CDCCCC@;>>AB@B@BBBBA>ACCCCAB<<@9?
@8FG
CTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTC
+
CCCFFFFFHHHHHJJJJJJJJJJJIJJJJJJJIJJJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJHHHFFDDDDDDDDDDDDDDDDDDDDDDDDEDDDCD
@8FH
CAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTC
+
@@@DA?AADD=DD?EF>B@E>BEFHFB;>E?BFB@9:C?:B?<FDGGDBG?B?F=CBB95@E7C@EEAC>DEE>;;>CCC@>CCC>A55?C5:<5:ABA@B
@8FI
TCTCGATGGAGTGGGTCCCATCAGTTTGAACAGTTGTCTGGATCCATTTTGTGGATGGCACCAGAAGTCATCAGAATGCAAGATAAAAATCCATACAGCTT
+
B@@DDDFFHHHDHIIHHIIJJJJJHIJJIIGIIIIJJJJJIIIJIJIJJJIDHGGGGIIJJIIJJJJJIJHHHHHEEFFFFFDCDEEEDDDDDDDCD>CDD
@8FJ
CTCTGCCACAAACTGTGGTGATGACATCTCCTGTGACTCTCACCTCTCAGACAACTAAGACAGATGACCCCCAATTGAAAAGAGAAATAAGGTTAATGAA
+
CCCFFFFFHHHHHJJHJIFHIJJJJJJJJJJJJIJJJJJGJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJHHFFFFFFEEECEDDDDDDDDCCDDEDDD
@8FK
CTTGGCACTTTTGAGCGTGGAGTAGGATGCCTGGATTTTTCAAAAGCAGATTCAGGTGTTCATTTATGTGTTATTGATGACTCCAATGAGCATATGCTTAC
+
CCCFFFFFGHHHHHIJJHHIFHGIIJHIIJJJIIHGJJJJJJJJIJJJJIJIGHIJFHHHJIIJJGIJHCEHGHHFDFFFFEEEEEDEDDDDDDDEDEECC
@8FL
GGGGGACACGTGAATATGGCATTCTCTCAGTCCAACCCTCCTTCGGAGTTGCACAAGGTCCACGGATCCAGAAACAAGCCCACCAGCTTGTGGAACCCAAC
+
1?++4=ADF:FFFFFFFBEF?CGFEEDEFBCFFFEFEEDGDBF<D0---=@F@FFEC;@A).7;?'='6>ABB;5?<9??(9<@B<?4@?24<ABABBB?@
@8FM
GCTGGAGCTCATGGCGGGGGGGGGCCCCCAAGCCCTCCCCCGCGAGACCCCCCCCCCCCCCCGCCCGCCCCCCCCCCCCGCCCAGCTGGGCCCTCTGCACC
+
===AAAAABCBCBCCCA::A751&&)&)))((+223(8()6&&)&&))8:(07:57&&050&&)0&&&)555;&09;3&0050&(((+3(++08(+(((+(
@8FN
CCATGTATATGCAGAATACTGTCAGTCTAGAGGAAGAGTTAAGAAAGGCCAACGCAGCGCGAAGTCAACTTGAAACCTACAAGAGACAGGTAGTAGAACT
+
CC@FFDEFHFHDDIGIJJJIGIIIIIGIJHHJIIJJIGBFHHHIGIJHIJJJJIJEHIGIGEFD=CEEDCDCCDDDDDDCDDDCBCCCCD>@C@@CCCCD
@8FO
GAAGCTGGGCCGCGTGGTGCACATCATCCAGTCACGGGAGCCCTCCCTGAAGAATTCCAACCCCGACGAGATTGAAATCGACTTTGAGACCCTGAAGCCGT
+
CCCFFFFFHHHHHJJJJFHIGJJJJJJJJJJJJIJJJJGGIJJHHHHFFFFDEEEDEEEDDDDDD@BB@BDDDDDDDCCBBDDDDCC?BDDDCCDDCDBDD
@8FP
CCACAGAGACCTCAAGAGTAATAATATATTTCTTCATGAAGACCTCACAGTAAAAATAGGTGATTTTGGTCTAGCTACAGAGAAATCTCGATGGAGTGGGT
+
@@@BDDDDHAHHHIG>F:3ADHEHIIIIIIGIIIIIIAHGHB?FHHBHIHIIIEHEBB@D/9BBBFGGGHEGEHCGHDEEHEEH??>>BC@@>A?=A=;?=
@8FQ
TGCAACTTCTTATGGACAGCCTCCCACTGGTTATATTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGAT
+
@C@DFFFFGFHHHJJJJJJJJJJJIJGIJJHIJJJJJJJJIJJJJJIIJIJJJJJDIIIHHHHHFFFFDCDEEDCDDDD;@CC?AACCCD>CCCDDDDDD
@8FR
CGGGACTCGAGTGATGATTGGGAGATTCCTGATGGGCAGATTACAGTGGGACAAAGAATTGGATCTGGATCATTTGGAACAGTCTACAAGGGAAAGTGGC
+
@?<:AADB??DDFE:<A@FA?;?A<EEFIF<FDFDCADBB9?9?0?9B9;F8-BFEEF@EEAE737;>3?ABB;A>>CCC;>3>3(;@B;<5(5<,(5,<
@8FS
GTCCAGGCTCTCCGAGGACGGGCTGCATAGGGAAGGGAAGCCCATCAACCTCTCTCATCGGGAAGACCTGGCTTACATGAACCACATCATGGTCTCTGTCT
+
@??BDB;BCCBFFHEIIIGHIDD@@??BGD<8DD;C:=CG;DA@HHHFEEDDFF?66@;;9;BBB?CC>CB<C8A@C>4>4@B?8?3>:A>(:444>:4:3
@8FT
GTGGATGGCTCCAGAAAGTTTGATGGATGGAATCTTCACTACTCAATCTGATGTATGGTCTTTTGGAATTCTGATTTGGGAGATTTTAACTCTTGGTCATC
+
@@@FFFFFHHHHHJJJJJHHJJJJJJJIJJJJJJJJIJJJJJIJJJJJIJIJJIHIJJFJHJJJJJJJJJIJJIJIJJHHFFFFFFEEEDEEEDDDDDDDD
@8FU
ACAAGACCGCAGGATGGAAACAAGCCCACTGAGACTAGTCAACCTCAATCTAGCACAGGGGGTTACAACCAGCCCAGCCTAGGATATGGACAGAGTAACT
+
@@@FDDFFHHHHHJJJJIIIJIIGIJJGHJGGIJJGJJGHGIEGCIJJJJJJJJJCGIFCFBBDDCDDCDBABDDDDDD<CDDDDDDDDDCDDDD@CCCD
@8FV
CCACACTGCGTGAGCTGGAGCGCTATGTCACCTCCTGTTTGCGGAAGAAAAGGAAACCTCAAGCTGAGAAAGTTGATGTGATTGCCGGCTCCTCCAAGATG
+
?@;:DBDDF:8CFEFD?F;;EFEE>GCFF9BBDEEAADFDADDF<F<ECEF@CCEEDBD??;;;>AB=>>A>;:>;@@@B;AA:3><B95<??9>?B><4:
@8FW
ACAAAATTAGGATTGCAACTGGACAGATAGCTGGCGTGGATAAAGATGGAAGGCCTCTACAACCCCACGTCAGAGTGTGGGATTCTGTTACTCTATCCAC
+
CCCFFFFFHHHHFIIJJJIJJIGIIIJIIIIIJJIIDEHEGHJGIJJJIJJIIIIJIGGIIJJIHHHFB?CDDCDAC@A??ADDCDEEDDDDDDD@CDCD
@8FX
TGAAATTTCAACCACAGCAGATGGCTGCAGTTCAGAGGTAAATGGCTGCTGTTTTGTGATGAGAACAGGAGAGCCTACAAATTTATTAAGGGAAGAAGAAT
+
7>1<?,2+,<>C=C<A;+?+3++3<+++11:?47??==*?A**?A)0))*0/=ABAAA)).=A4;)=AA6(61((;)7(;(;(55;=;>;?;5,59;;>9=
@8FY
GGCATTCAGAAAAACAGGCCAGCTATGAACTATGATAAACTTAGCCGTTCACTCCGCTATTACTATGAGAAAGGAATTATGCAAAAGGTGGCTGGAGAG
+
@@@FFFFFFHGHHIIBGGHIIEC>BCHGIAHHIGEGIIADHAAEGHIAHDH9<FHI:GBGIG<DCCE>AEEC@D@B>CC:@@>@C?A@-;<(9<B??:?
@8FZ
CAGCACTTTGTGCACCGAGACCTGGCCACCAGGAACTGCCTGGTTGGAGCGAATCTGCTAGTGAAGATTGGGGACTTCGGCATGTCCAGAGATGTCTAC
+
@@?DBDDDHDADD<<<@88CCFBE??F9?;?B6?BG?BG@8/8F3;73=@@EA=17?;;;;77>>;66>>=;;<@BCC<29B<<>:::4++<A3(+4:A
@8G0
CTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACC
+
C@@FFFFFHHHFHIGGIJIJJIJJGGHIGIJJIJIIJIIIJJJJJEGHEHIJIJIIIFH6?CEDDEEDDB;ACCDACCA@CCCCDB?BDDDDDCACEDCCD
@8G1
CCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGC
+
?BBDDDDDHHHGHJJJIHJJJJJJJGIIJJIJIIIIIJJIJJJJJJJIJJJIJIJIJIIJJJJJEHHHFHHHFFCEEFACCDDDBBDDDEEDDEDDDDDD
@8G2
ATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCC
+
@C@DDFFFHHHHGIJIIIJJIIJJJIGIIIJJJJJJJJIJIIJJGJJIJGHHHHGD;BEFFEEEEEB>BBDDDDDDDDDCDDDDCDCDCDCDDCBDDDDD
@8G3
TGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTAT
+
@<@DDDFDHFFHDIIDHIIIGBE@CGGHGGIIICHEDDHGGIIIGGIIIIEIIIIIGHGED>?CDEECEECCBCACCCCCCBBBBBBBCCCCDCACCCCC
@8G4
CTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGC
+
C@CFFFFFHHHHHJJIJJJJIJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJIJJIJJJJJJHHHHFFFFFFEEEEEEDDDDDDDBDDDDDDDDDDD
@8G5
TGTGTTTTTGCAGCCTCTACAACCCCACGTCAGAGTGTGGGATTCTGTTACTCTATCCACACTGCAGATTATTGGACTTGGC
+
?@=DBDDFHAFHFGIGIGIJJEGHGIIJJFHGGGHBDBFHGIIIJJJIIGHGHIIGIIJJEHIHFHGADB;CCDFCEECECD
@8G6
CTTTCCAGATAATCAGCGTCCACTGCTGAAGACAGACATGGAACGTCACATCAACGAGGAGGACACAGTGCCTCTTTCTCACTTTGATGAGAGCATGGCCT
+
CCCFFFFFFHHHHJJJJJGIJJIJJJJJJJIJJIIIJIIIIIIIJJJIJJJJIJJJJJIJGGHHFFFFFEEEDEEDCDDDDDDDDCCDCEDCCDDDDDDCD
@8G7
GTCCTTCCAAGAAGCAAAAAAAAAAAGAGAAAAACGTCAAGCAGTAAACATGATGTGTCAGCACACCATGATTTGAATATTGATCAATCACAGTGTAATG
+
@@@DDD;+CFDCBGFEGFDFFIIFFI'(.=CFCF@E=2;A;@B?.;@A9A6(;>:(--;@(:3592(,5(:4>((++(4:>:>::BBB(>(:(4>::4:(
@8G8
ATTCAGACTAGAAGCAGCCAAAGATGATTATCGAATACGTTGTGAAGAGTTAGAAAAGGAGATCTCTGAACTTCGGCAACAGAATGATGAACTGACCACTT
+
CCCFFFFFHHHHHJJJJJJJIJJJIJHIIJJIJIJIJJJJJJJJJIJJIIJJIJJJJJJJIGIJJJJIJIGHHHHFFFDDEDDDCDDDCEDDDDDDDDDDD
@8G9
CAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGC
+
@?@DDDDDHHHFHEGGHIFAGGGIIEGHIIIIIIIIII?DFHGIIIEFGGCGGIIIIEEHIIIIHGHHGFHDBEFDDC?A?>ADDCCCDCDDCCCCDCDCC
@8GA
CTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTT
+
@@@ADDBDHFHDF?C1:E>9EHIIE9A:E9@B@9?FCGEEDB;F9DBDFFHGC@GGHCG@G>DECEE=EEAD;@;ACCCCEDCCCCCC?CBBB6/509C@@
@8GB
CCTATCACGACAAATCACCGGCCTTCTCCTGACCCCGAGCAGCGGCCCCTCCGGTCCCCCCTGGACAACATGATCCGCCGCCTCTCCCCGGCTGAGAGCGC
+
=:;B?B4,=+<<@?<EEDFIAADDDB9BD????BD@6-76@=AD<849<=31>83;=?=50028>1:88+3>44:><>?>??55(+>A;)00&02+(:(09
@8GC
AAAAATAATAGCAGCAACAGCAATGTGAGCAAGAAGGAGCCAGCGCCCATGAAGAGCAAGCCCCCTCCCACGTATGAGTCGGAGGAAGAGGACAAGTGCA
+
CCCFFFFFHHGHHJJJJJJJJJJJJHIJJJJJJJJJJJJJJIJIJJJJJJJJJIJJJJJJHHHHFFDDDDDDBDDDDDCDDDBDDDDDBDDDDDDDDDDD
@8GD
CCGAACTACACCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATGACATCTCCTGTGACTCTCACCTCTCAGACAACTAAGACAGATGACCCCCAATTG
+
@@@DDD?DHD;FDH+AEG<HHGEHIB@CFGGEFGEIFH?DHGIICGGIIGDDHHG>BF@GHEF@=@CDHIG3A?;EEBEEBD@>C;ACCACCBBBBBCCC
@8GE
AACTCTTTCATCTGCTGCTAAAAGTGGTACAGAAAAAAAGAAAGAAAAACCACAAGGACAGAGAGAAAAAAAAAAGAGGAATCTCATTCTAATGATCAA
+
?<@BBDBD8FHHDH44?BCHGHCH3<CAHFGBEGFFEH6?@?DDDGIGIEC=5=FGG@ACE@A@;7@DCA8?B9>B<?@B?AC@C3@DCA:@C>44>CC
@8GF
GAATTCCAACCCCGACGAGATTGAAATCGACTTTGAGACCCTGAAGCCGTCCACACTGCGTGAGCTGGAGCGCTATGTCACCTCCTGTTTGCGGAAGAAA
+
CCCFFFFFHHHGHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJGHFFFFDEEEDDDDDDDDDDDDDDDDDDEEEDDDDDDDDDDDDDDDDDDDD
@8GG
CGACAGGGGTAACCTGGGGCTGGAGGGAAGCTGTACTGTCCCACCTAACGTTGCAACTGGGAGACTTCCGGGGGCCTCACTGCTCCTAGAGCCCTCTTCGC
+
CCCFFFFFHAHHHJJJIJIJJJJJJJJHIJIJIGHIIIJJJJJIJJJIJJIJJHHHHHFFFFDCDEDDDDDDDDDDDDCDDDDDDDDDDDDDDDDDDDDBB
@8GH
CCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTTATCCAGCCTATGGGCAGCAGCCAGCAGCCACTGCACCTACAAGACCG
+
CCCFFFFFGFFFHJGHIJJGGIIIIGIIJIGIIJGHHIIGIJJJFJICGGIIJJGHIIGIJIJJJIG@EE>DFBDEBEDC?BD@=>AC:@CACCDDCDDDB
@8GI
CTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGACAGGACCACCCCAGTAGCATGGGTGTT
+
CCCFFFFFHHHHHJIJJJJJJJJJJIIJJJJJJJJJJJJJJJJJJIIJJIJJIJJIJJJJJHHHHHHFFFEEFCDDDDDDDDDDDDDDDCDDDEDDD9>>D
@8GJ
GAAAGACTCAATCAATCTGATTCTATAGAAGACCCTAACAGTCCAGCAGGAAGAAGGCATTTGCAGCTCCAGACTCAATTAGAACAGCTCCAAGAAGAAAC
+
@@@FBDFFFFHHHGIGIGIEGIIIEHIHHGDFHIJIJJIJJEGIEFDGFHFHDHHHHGBGIGGGGGI>CHEDE?CEEEEFFFFFAEC@CC@C?;ACC>CD?
@8GK
GACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTG
+
CCCFFFFFHHGHHIJJJJJJJIJJJIJJJIJJJJJJJJJJJJJJJJJJHIJIIJJJJJHHCHHHFFFFFFEEEEEDCDDDDDDDDDDDDDDDDDDDDDDDD
@8GL
CCTGAAGCCGTCCACACTGCGTGAGCTGGAGCGCTATGTCACCTCCTGTTTGCGGAAGAAAAGGAAACCTCAAGCTGAGAAAGTTGATGTGATTGCCGGCT
+
CCCFFFFFHGGHHJIJIJIJJIIIJJIJJIJIIJJJJJIJIIJIJJIJGGIIIJHBEDEEEEDCDDDDDDDDDDDDDCDDDDDDDDDDDCCDDDCCCDDD<
@8GM
TAAACACAAAATTAATAGAAGAAGAAAAGAAAACTCTTGAGCTAAAGGATAAATTAACAACTGCTGATAAATTACTAGGAGAATTACAAGAACAGATTGTG
+
CCCFFFFFHHHHHJJJJJHJJIJJJJJJIJJJJIJIIJGIJJIJJJJJJIJJJJJJJJJJJJJJIJJIIJIIJJHGHHHHFFFFFEEEECEDCDCDDDCCC
@8GN
CCTGAAGAATTCCAACCCCGACGAGATTGAAATCGACTTTGAGACCCTGAAGCCGTCCACACTGCGTGAGCTGGAGCGCTATGTCACCTCCTGTTTGCGG
+
@@CDFFDFHHHFFIJGJIIGHHHGGGIHHHHDGIDBHIIJGGEHIGIG=CCCHFEDFDCEC??CDDDD??ACCDBDCDDBBBDCDDDCCBBCCCCCCDBB
@8GO
ACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGC
+
CCCFFFFFHHHDHJJJIIJJJJJJIGGIJIJJJIIGHIGJJIGIJIIJIHHIIIIGHJIJJIGGIHHHFFDFF?CDEEEEEEDDDCBDD<ACDDDDDDDCD
@8GP
GTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJIIIJJJJJJJJJJJJJJIJJJJIHHHHEFFFFFFEDEEEEEDDD?CDCDDDDDDDDDDD
@8GQ
CAACCAGCCCAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTC
+
@@@FDDDBHHD=BFBHII>HHHDEAFGHCHCHID9?@DGBBABFDDHDGCDFDGCHIIFFGHIHIGECHHDEFFDABCCCCCCCA@CCBBCCCCCCCBA>A
@8GR
CTTTTTTCACCATTCTTCCACCCTGGAAACTCTATACACACACAGCCGGAGGTCATACTGCATCAGAACCATGAAGAAGATAACTGTGTCCAGAGGACCCC
+
@CCFFFFFHHHHHJJJJJJJJJJJJJJJJJIJJJIJJJJJJJJJIJJJJJIICHHEHHFFFFFFEEEEEDDDDDDDDDDDCDDDCDDDDDDDDDDDDDDDD
@8GS
CTCAATCAATCTGATTCTATAGAAGACCCTAACAGTCCAGCAGGAAGAAGGCATTTGCAGCTCCAGACTCAATTAGAACAGCTCCAAGAAGAAACATTC
+
@@<D=AABDA:DFGB@FGECD9AB4+<AC@GECG<GEGBGDFAEF;DGDF<FE3?FD=FBCFDFE)=D@@EEDFF;AE3?BB@7(;A@>BBABB<A@>@
@8GT
CCAGGGGCCCATGCAGAATGCCACCAAGTATGGCAACATGACAGAGGACCATGTGATGCACCTGCTCCAGAATGCTGACCCCCTGAAGGTGTACCCGCCAC
+
+1:?;=?8AA=CBCCA>3A2AA@BA==>*:??==A?)>;>ABBB>=A;5=A9>.=)/8=;A;AA>A=A@>>>@@@B>.;>=;6;=:=>:,9>;?:=;;;;=
@8GU
CTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTC
+
CCCFFFDDHHGHHJJIJFHGIIIGJIIIIJIIIJIIJDHGHJJIIGIJIIIJJIJJJIJIJJJIJIJJJHGEHHFFFFFEEEEEEDDBDDDDDDDDDCDDE
@8GV
CCTAGAGGGAAAGCGAGAGGGAGACGGACGTTGAGAGAACGAGGAGGAAGGAGAGAAAATGGCGTCCACGGATTACAGTACCTATAGCCAAGCTGCAGCGC
+
@@@DDDDDH>F?DEHGGGIIJGGIFII@FGGHGIGGIIIIJBHHBEFBBE?>==@BDDDDCCBDBBDDDBD>>BDDDDEEDDDDCD:@CCDADDCCDCCBB
@8GW
GCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTACGGGCAGCAGAGTTCATTCCGAC
+
CCCFFFFFGHHHHIIJJJJJJJJJJJIJJJIHJJJJIJIJJJJJJIIIJJJGIJJIJJIJIJJIJHHHHHFFFFFCDEEDBDDDDDDDDDDEDEEEEEDDD
@8GX
GCAGTTACAAGCCTTCAAAAATGAAGTAGGAGTACTCAGGAAAACACGACATGTGAATATCCTACTCTTCATGGGCTATTCCACAAAGCCACAACTGGCT
+
@@@DDEFFHH3AD@AGEGIIIIIIGIHGHI>FEHIGIIGGIIIIIII<G@@@FBFHEIHFGCDCGIGGHCHHFFFFFFFFEAACCDDDDDDCDDDCDCBC
@8GY
GAAGAATTCCAACCCCGACGAGATTGAAATCGACTTTGAGACCCTGAAGCCGTCCACACTGCGTGAGCTGGAGCGCTATGTCACCTCCTGTTTGCGGA
+
C@@DFDFFFFHGDHIJJIGFGGAHHIHIJJ@DHIIIJGAHIIJJJDGIGIJBADFFDEDCCC@?BBBCCCD<A?BBD<@DCDEDDADDDDCDDDCBD@
@8GZ
ATCTCCTGTGACTCTCACCTCTCAGACAACTAAGACAGATGACCCCCAATTGAAAAGAGAAATAAGGTTAATGAAAAACAGAGAAGCTGCTCGAGAATGTC
+
CCCFFFFFHFHHHJJJJJJJJJJJJJJJJJJJJJGIIJJJJJIJJIJJJJJJIJJJIIJJJJJJJJJ@EHHHHHHFFFFDEEDEDDDDDDCDDDDDDDDCC
@8H0
AGACCGCCTATGCAACTTCTTATGGACAGCCTCCCACTGGTTATACTACTCCAACTGCCCCCCAGGCATACAGCCAGCCTGTCCAGGGGTATGGCACTGGT
+
CCCFFFFFGHHHHJIJJJJJJJJIGIJJJJJJIJJJJJJJHGIIJJJJJJJJJJJJIJJJJHFDDDDDDDDDDDDDDBDDDDDDDDDDDBDCDDBDCDDD:
@8H1
TCATCAACCAAGAAGGAGAATATATTAAAATGTTTATGCGCGGTCGGCCAATTACCATGTTCATTCCTTCCGATGTTGACAACTATGATGACATCAGAACG
+
@@@DBBDFHAF>DBGHFGBEFGIGIIHIICHGIIHAFFE@GDHDHAH@GBGHEEHE=?DBBD<BFC@AECEBBCBBCCCCCCCCCCCCECDCCCCCCC>CB
@8H2
CAGCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCT
+
?@@?DBDDHHFHG@GC@HGCBHCFBF@GH@HGEFGCEGHGG<BCGHII;?DGGHHGHAHGDCA;CEHC?EE>7?@BB?BACACEBCCCCCCABC@CA@C@C
@8H3
CTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCT
+
CCCFFFFFHHGHHJJIEIIIIJJJHIJJJJJIJJJIJJJJJJJJJJGIJIJJJJJJJJJJJIIJJIJHHHEHFFCDDDDDEDEDDDDEDDDDDDDDDDDDD
@8H4
GGACATCCTGACGGCCTCTTCCACCTCTTAAACCTTCTTCCCGGACAAGCCTAACACCCAATATCCCCATGCGGTGGAGGAGAACCCCCTAGAAATTGCTG
+
(;5:(8=>:<8@(((-2(22.=<)8.983)6)))03)))0:.(09=8>86=):3=)==?9(.:3:6(56(((,358'((((+222()56&2((+(+((6((
@8H5
TATAGCCAAGCTGCAGCGCAGCAGGGCTACAGTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGG
+
@?8D;B?DAFF?DGGEHG?FDE98;DAAG@HI@G<DEG3?FHIDE8A(@;AECBEEEECCCCC>@@;;5;????BB858?B@C@@>8?CBBBBBC9@C:(4
@8H6
ATCCAGAAGCCCTTTTCTCCATGGCCTTTCCAGATAATCAGCGTCCACTGCTGAAGACAGACATGGAACGTCACATCAACGAGGAGGACACAGTGCCTCTT
+
C@CDFDBFHHHHHGIIIICHIIIIIIIIIIIIIIACGHIIIIGFHEHGGHIGHIGIICFHEHIGIGGIIEEHBD>@CCEEAC?@;?B8ACD?BCDCCCDAC
@8H7
CAACAAATGAAGTTGTTTTGGCTGTGGAGTTTCACCCAACAGATGCAAATACCATAATTACATGCGGTAAATCTCATATTTTCTTCTGGACCTGGAGCGGC
+
@@@FDDDDHAFHCFHF@EGDHIGIGGG@HHGGHIGHGIIIIIIIIIGIIII>@GGGGHGIIIIGGEGFGFEDE@DDDDEEEEEDEECCDCDDD?B?<ADD>
@8H8
TCCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCT
+
CCCFFFFFFFHDGIJIJJJHGIIJGIJJJIIJJJJGIIJIJJJGGHHIJIJIJJIJIIIIIIGHHHHHFFFFFEEDECCCCDDDDCDDDDDCDC@CCABBD
@8H9
AGAACTTCAGAAGAGAAATCATAAAGACAGCCAGTTCGAAACTGATATAGTACAACGAATGGAACAAGAAACACAAAGAAAGTTAGAACAACTCCGGGC
+
@@<?;ABB?:4<DE??EFIIDF?CBEHIIA?;CB:*::CCFGD@DBDDBBFB4B>G6BFEGD@F@E@>EAEFAHDEEE@ACC6;@3>>@;??>:C<=:5
@8HA
GTTAACTCTATACACGCACTTCTGGAAATCATACTGCATCTCAACCATCAAAAAGATAACGGCGTCCAGGGAACCCCCAAGACAACCGCGGATAACGTACT
+
(((2(2.=8=<9=1:((((())28=>))):>>)).)1))00.9)7:3)))0))<9(..))-''-,,363('(72;7;2;(+(+((22:-)0&&&+((+(2(
@8HB
GCCTAGGATATGGACAGAGTAACTACAGTTATCCCCAGGTACCTGGGAGCTACCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTAT
+
CCCFFFFFHHHHHJJJJJJIIIJJJJJJJJJJJJJJJJJHIJJJJJJIJJJJJJJJIJJJJJJJJJIJHHHHHHFFFFFEEEEDDDDDDDDDDDDDDDDDD
@8HC
GAACGACATGTGGCCACTCTATCCATGCCTTCCCTAGCTGACCACTCCAAAATTTCCAAGGGCGATTATGAGCAATTCAGTTAGTGGCAGCGCTACAATTC
+
0(((((((-):;46@):.)=<??)2)9:>8@=)))96):3)6:)()0=77)(83)<6;);((8=',(,..(((.((-3((-(,(,5;6(85:-(&)(((((
@8HD
TACCGCCTGATGCTGCAATGCTGGAAGCAGGAGCCGGACAAAAGGCCGGTGTTTGCGGACATCAGCAAAGACCTGGAGAAGATGATGGTTAAGAGGAG
+
8?@FDDADFBHFHIIDBFGG@BHIEGGGG;=CC;DDG:FHIIGGGII>EBDFFECCCBBBB@>C:@@CC9C?CCCBB?CB??>@:3@C(4@CC@CB??
@8HE
GTGCTTACACCGCCCAGCCCACTCAAGGATATGCACAGACCACCCAGGCATATGGGCAACAAAGCTATGGAACCTATGGACAGCCCACTGATGTCAGCTAT
+
@?@BDFFFGHHHDEHGGGIGIJJJIGIGGIIIJGIJJJEGIIIIJIJIJIJI@HGIHHHHFFFFDECACCACCBCCADDCCDB@A?BDACC>A>ADCCCCA
@8HF
CCTGTCTCCAGATCTCAGTAAGGTACGGAGTAACTGTCCAAAAGCCATGAAGAGATTAATGGCAGAGTGCCTCAAAAAGAAAAGAGATGAGAGACCACTCT
+
?<=4ABDDDDD8AAEED@<AFEEA?FFA88:?CEAD?<:DDD=BDD3D?@D*8B98BDD:/B(8;@6).=CD3=7?>??1;>A35,((5(5>(5<=,(5((
@8HG
AGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGG
+
;?@DDDADFBFDFGIBHIIII:GGHIFIIIIIIIIIIHFIGIIGGFHHGGIIIIGIIIIICHEHGIIHHHHDB>B@?@C@>@ACCABBCBC<4@CCCCCCC
@8HH
AGAGCAGTTACTCTCAGCAGAACACCTATGGGCAACCGAGCAGCTATGGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACT
+
@CCFFFFFHDFHGIJHGIGIIIIIGHIIHHGGHEGGIJJGIJHIGIJIJJGIIJJGIGEDEGHFHHHHFFFFFFECEEDDDDDDCBDDB?BABDDCDDDAA
@8HI
CCAGGGGTATGGCACTGGTGCTTATGATACCACCACTGCTACAGTCACCACCACCCAGGCCTCCTATGCAGCTCAGTCTGCATATGGCACTCAGCCTGCTT
+
@@@FFFFDDFAHHEHGHEHIIJIGIEGGIEG@GGHGGGGGGIHIIIJIJJIJJIJGIFEHIAHHHGHGEFBDDAEECCECCDCDCDDDCCCDCCDDCBDDA
@8HJ
GGACAGCAGAGTAGCTATGGTCAACAAAGCAGCTATGGGCAGCAGCCTCCCACTAGTTACCCACCCCAAACTGGATCCTACAGCCAAGCTCCAAGTCAAT
+
CC@FDBDDDF?CDGHHBEB?<CHBGGEIGI>CDHIIGIIIBDH9?FHHIHI@BGHCHGHIIIIIIHFFFFF;BCECCC;A@C3>BBC?BCCCCC>::AC4
@8HK
TGACATCTCCTGTGACTCTCACCTCTCAGACAACTAAGACAGATGACCCCCAATTGAAAAGAGAAATAAGGTTACTGCAAAACAGAGAAGCTGCTCGAG
+
==+2??<+?B7+22,<C=+?@CAC>>7<A@@CBB<A<AB<A)0?7*09>8(0===)))=ABA>7>=.>>)=.=.)).))).(.((;3,;(;??A?(,3'
@8HL
ATCAGTTTGAACAGTTGTCTGGATCCATTTTGTGGATGGCACCAGAAGTCATCAGAATGCAAGATAAAAATCCATACAGCTTTCAGTCAGATGTATATGC
+
CCCFFFFFHHHHHJJJJJJJJJIJJJJJJJJJHHIJIIJJJJJJIJJGDGIJJJIJIIIJJJIJIIJJJJIIJJJJHHHHHFFFFFFFDEEDE@@CDDDD
@8HM
CAGACAATAGCTGAACAAGAAAGTAAACTTAATGAAGCACATAAGTCCCTTAGTACAGTGGAAGATTTGAAAGCTGAGATTGTTTCTGCATCTGAATCC
+
@??BDDD?DFBDDHIHGIGHGHIHEHIEF>HHD??FCEGGF<DGGIIGHHCHBGHGG@?FFDEEEGGFGFGH>===;C;?EHEEF@?@D>AECCEE@>@
@8HN
CTATGGACAGCCCACTGATGTCAGCTATACCCAGGCTCAGACCACTGCAACCTATGGGCAGACCGCCTATGCAACTTCTTAT
+
CCCFFFFFHHHHHJJJJJIJJIIJJIJJJIJIJJJJJJJIHIJIJJJJJJJJJJHJJIGGIGIJHGFFDEEEEDDDDDDDDD
@8HO
CCCCATGCAGCCAGTCACTGCACCTCCATCCTACCCTCCTACCAGCTATTCCTCTACACAGCCGACTAGTTATGATCAGAGCAGTTACTCTCAGCAGAAC
+
C@CFFFDDDHGHHIFHIIIJGIIJIFGGGIIGGIIIGIICHIGIIJEDGGIJJIGHIGGEAHEHIBEFFCFFFDEECEEECDDDCCDCDDACCACA?CC<
@8HP
ACCAGATAGCAGCTACCCCATGGACCACAGATTTCGCCGCCAGCTTTCTGAACCCTGTAACTCCTTTCCTCCTTTGCCGACGATGCCAAGGGAAGGACGTC
+
:::<++<7?=>=A+2?A==;+<377ACAB;**:?7)):?=A<65>AA>=4>7.5:>3A>>>?@@@@@>36(;@??=>5=/8==229:8(899((((99.5;
@8HQ
GCAAAGCTCTCCTGCTGCTGACCAAAGAGGACTTTCGCTATCGATCTCCTCATTCAGGTGATGTGCTCTATGAACTCCTTCAGCATATTCTGAAGCAGAGG
+
@@@?DDD:AFAFHHBDBFGHHIIIGCHGGG;CFEHE@DHDBHIICHHGGFHBFHGG@A7=CHE=@EGIAHFCEAECCEEEEAACCCCCCD;@@CCA?CCBB
@8HR
GGAAAACACGACATGTGAATATCCTACTCTTCATGGGCTATTCCACAAAGCCACAACTGGCTATTGTTACCCAGTGGTGTGAGGGCTCCAGCTTGTATCAC
+
@@CFFFFFHHHHHIGHGIIJIIJJJIJIJGJJGHDGIDGGJJIJJJJJJIJJJJJIJJEGIJJIHIIHHHHGEF@CD@A;;>CDBDBDDDDDDDDDCEECC
@8HS
GAAGAATTGAGCTTTTCAAGGGAACAGATTCAGAGAGCTAGACAGACCATAGCTGAACAAGAAAGTAAACTTAATGAAGCACATAAGTCCCTTAGTACAGT
+
?:8=DD:DC?DDBEE@<,<CDEEE;B@F@BEADBBED??CB?D@DIIIAEBBB99<.=<B87A@C8==AD=@?CADDCCD;?@AAAA6;6-5>:>3-5:>B
@8HT
TGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACACAGAAGAGTGACACCCGCCTCTGAGACCCTAGAAGACCCTTGCAGGACAGAGTCCCAGC
+
CC@FFFFFHHGHHJJJHIJGHIIIJIHHIIIIGIIJIJIGIGIGH@GG@ECAECCEFFDDDDDDCCCDD@DDDDDD@CCCDDDCDCABDDCDDDA@CCCCB
@8HU
CCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACATCCACCGACACAGAAGAGTGACACCCGCCTCTGAGACCCTAGA
+
CCCFFFFFHHHHHJJJJJIJJJJJJJJJJIJJJJJIJJIJJIGIIJJJJIIIIGIJH)?EHFFFFDDDDDDDDDDD>CDDDDDDDBDDDDDDDDDDDDCCC
@8HV
CCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACACAGAAGAGTGACACCCGCCTCTG
+
@@@DFFDF@FFHGEGGHGHIIIJIGIIJGDGIJEGI?FHDHICCGHIIICHE:C;BC@CEEEDABBDD@BB<CDDBDDB?@DC?A?(:@CCCDDBBD<B:>
@8HW
GTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACACAGAAGAGTGACACCCGCCTCTGAGACCCTAGAAGACCCTTGCAGGACAGAGTCCCAG
+
C@@FFFFFHHGGHIIIJHIFHIIJCHIIGJCGGHIH;FH<AH>GGIIIIHHECEFFFDADDDBDDDDDDDDDCCCDDDDDDDDDDCDDDDDD?C>:@ACCC
@8HX
GCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGG
+
CC@FFFDDDHHGHJJJJJJJJEIJJJJJJJIGIJI?GEHGDGFHIJHHFHEEFFFFFDDDEBDDDDDDDDDDDDDDD??ACDDCCDDDDDDCC:@?B@D@0
@8HY
GTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGG
+
C@CFFFFFHHHHHIJJJJIJJJJIJJJJIJJIJJJIIIGIIJBHDHHHHHDFFDEEEEDCCDDDDDDDDDDDDDDDDDDACDDDDCCDDCCDDCAAA@@BB
@8HZ
CAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACACAGAAGAGTGACACCCGCCTCTGAGACCCTAGAAGACCCTTGCAGGAC
+
CCCFFFFFHHHFHIJJJJIJJJJJJJJGHGIJJJIJJJGIJJJGGIIJJGHHHFFFFEEED;CCDDDDDDDDDDCDDDDDDDDDDDDCDDDDDDDDCCDDD
@8I0
CGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCA
+
@@CFFFFDHHGHHEIBGHGIGHJJJEICIICIIIJIGHIIJIJIHIIHH8@?CEEEDBDDDDCDDDDDB?ABDCDDDDDDCDDDDDACDCCD>@CBCCCDD
@8I1
CGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCA
+
CCCFFFFFHHHHHIJGIIJJIIGJJIJJJJGIIGIJJIJIEIIFEHJHHFF?CCEEDDDDDDCCDCCDDDDDDDDDDDDDDCDDDD<CCDDDCDDDCDDDA
@8I2
CTCGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCT
+
@@@FFFFFHHDHHGIIGEGGHIAHHIJIJIIIIFIJJIIHIGHIIGCD>A??A;ACDDDDDDDD;?CCADD?BDDCCCCCCCCACD@B299ACCACCBCCD
@8I3
CAAGCAGTTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACACAGAAGAGTGACACCCGCCTCTGAGACCCTAGAAGACCCTTGCAGGAC
+
CCCFFFFEHGHFHJIJJJJJJJIJJJJGIJIJJJJJIJIGJJIJJJJIJJIHHFFFFEEDECCDDDDDDDDDBDDCDDDDDDDDDDCCDDDDDDDDDDDDB
@8I4
CTCGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCT
+
@@@DDDDDHHHD?EH:E:E??F@D6@GD@FEGBDGBG>B6FC;BHE6CBB??B,;>@C>;?BB<;9:>>CB8829@@CCC>4:<CCBB8?<C@>3>@?###
@8I5
CTCGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCT
+
CCCFFFFFHHHHHIJJJHIJJJJJJJJJJJIJJJJJJIJIFIGHIGDCEEDDDACCCDDBDDDCCCCDCCBBDDDDCCCDDDDCDDBB?CDDDDDDCBCCA
@8I6
CACCTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTA
+
CCCFFFFFHHHHHJJJJJIIIGIHGGGIIIJJDIJIJIEGIHIEFGIIJHEA;?>BDDD?CCDDDDDDBCCDDDBDBB?BDDDCDDDCDDDDDD8?CCCD@
@8I7
GTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACACAGAAGAGTGACACCCGCCTCTGAGACCCTAGAAGACCCTTGCAGGACAGAGTCCCAG
+
B@BFFFFFHHHGHJJJJHIIJIIJJJJIHIIJJJIJIJJJIJJJJIJJIHFHHHFFFFDCDDDDDDDDDDDDDDCCDD?CDDDDDDDDDDDDBDD>CDCC>
@8I8
CTGGACCGTGTCCTTACCGTGACGTCCACCGACACAGAAGAGTGACACCCGCCTCTGAGACCCTAGAAGACCCTTGCAGGACAGAGTCCCAGCACAAAGCG
+
CCCFFFFFFFHHHJJJJJJEHIJJGIIJJJJIJGGIJIJIIJCFHJJJJJHHFFFEEEEEEDDDDDDDDDDDDDDDCDDDDBDDCDCCDDDDDDDDBBCCB
@8I9
GCCGGCATTCCTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGG
+
CCCFFFDFHHHHHJJJJJJJJJGFHDFG:F??BDHBBAFHACGHIAHHHECEDFDDCD>=?>@?8@2?>@CBB>@B@><@@ACD1?ACCCCCCD=><:@@D
@8IA
GAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACACAGAAGAGTGACACCCGCCTCTGAGACCCTAGAAGACCCTTGCAGGACAGAGTCCCAGCAC
+
;;?DB?A?;3A?<ECB3:CHBHHI6::8D??)00??:FHBFHB@=@7.@).)7=?'9>A<>55@CC@85?99>CC>C3+9C3:C(82+923+4>:A>AB3?
@8IB
CTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACACAGAAGAGTGACACCCGCCTCTGAGACCCTAGAAGACCCTTGCAG
+
@C@DDFFFHGHHHIGCHBHIIIJJJJJJJJIBFGHIJJJJJJJGIIJJJIJIJJFFFFCEEEDD@CCDDDDDDCDDDDDDCACDDDCDDCCDD?BCACDDC
@8IC
GGAGCACAGACCCCACCGTGCCGGCATTCCTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTG
+
@@@FFFFFFHHGHIIJJJIIJJJIJJJJJJJJJJJJIJJJIA@@EEHBC?@@CE>B@DBCCCDECDDCDDD;B@?>B@?BB<B>9+>CDD9>5@?CC?C>A
@8ID
TGGACCGTGTCCTTACCGTGACGTCCACCGACACAGAAGAGTGACACCCGCCTCTGAGACCCTAGAAGACCCTTGCAGGACAGAGTCCCAGCACAAAGCGG
+
CCCFFFFDHHHHHJJJJIGHIJJIIJJJJJIJIGIGGJIGICHGIGHIJIHEFFFEEEDEDDDDDDDCCACDDDDDCDBBDDDDDADDDDDDDDDDDCD@5
@8IE
CGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACACAGAAGAGTGACACCCGCCTCTGA
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJIJJJJJIIJJIJIJJJJJJJJJHHHHFHFFFFFDDDDDDDDDDDDDDDDDDDDDDDD@CDDCDDDDDDDDDDC
@8IF
CGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACACAGAAGAGTGACACCCGCCTCTGA
+
CCCFFFFFHHHHHJJJIJJJJJJJJJJJJJJJJJJGIJIJJJJJJJJIJJHHHHGHFFFFFDDDDDDDDDDDDDDDDDDDDDDDD>CCCCDDDDDDDDDDD
@8IG
CTGCGGGAGCACAGACCCCACCGTGCCGGCATTCCTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTG
+
@@@DDDDD:F;AF?FGBGHGBHHIIABGHIGGAHICHIGEAEECBEE;?<?@:;8>CAC7@;BBC>>ACA@ACC@@9>?<5()<@>>@<9?C::AB599?A
@8IH
CTTACCGTGACGTCCACCGACACAGAAGAGTGACACCCGCCTCTGAGACCCTAGAAGACCCTTGCAGGACAGAGTCCCAGCACAAAGCGGAGACTCCGCAC
+
C@CFFFFDHFHHHIIIJJJJJJJJJIJIIJDGIJGHJJIIJJJGIJIJJHHGHFFFFFEEDEEDDDDDDDDBDDACDDDDDDDDBDCDBB<BBDDCDDDDD
@8II
CCTGGACCGTGTCCTTACCGTGACGTCCACCGACACAGAAGAGTGACACCCGCCTCTGAGACCCTAGAAGACCCTTGCAGGACAGAGTCCCAGCACAAAGC
+
CCCFFFFFHHHHHJJJIJIJHIHIJJJJIJIJIIJJJJJJGGI@GIJJJJHHHFFDEEDEDDDDDDDDDDDDDDDDDDDDDDDDDDCCCCCDC<ABD<BC?
@8IJ
CTTAGGGATTGCACCAGGAGGCGAAGTGGCCACTGCTGCGGGAGCACAGACCCCACCGTGCCGGCATTCCTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGC
+
@@@DFFDFBFDHFIIJBBBDGIGHGDBFGHHIJIGHGGIIIBEEBBB?@CEDBDDDDDABBDDBDBDDCDDCCAC9-?<@B>B?><>@B@CDCDBD<>@CD
@8IK
CCTGGACCGTGTCCTTACCGTGACGTCCACCGACACAGAAGAGTGACACCCGCCTCTGAGACCCTAGAAGACCCTTGCAGGACAGAGTCCCAGCACAAAGC
+
@@<DDDDDFDDHDBEHGGDGCGDE;?FHCF>GI>DFG>FFHH@)8=;=DA;ABD>BCC>@;(;ACC?C>:>5,9<?A@CC<<8<<C9(4(4>CBC?CA###
@8IL
CCGCAAGCTTCCTTAGGGATTGCACCAGGAGGCGAAGTGGCCACTGCTGCGGGAGCACAGACCCCACCGTGCCGGCATTCCTCCTCGGCTCCGTGCGGAGT
+
CCCFFFFFHHHHHJIJJJJJJJJJJJJJJJJJJJJJJGIJJJJJJIJJJIHHFCDDDDDDDDBDDDDDDDDDDDDDBDDDEDDDDDDDDDDDDBBBBB9@<
@8IM
CCGCAAGCTTCCTTAGGGATTGCACCAGGAGGCGAAGTGGCCACTGCTGCGGGAGCACAGACCCCACCGTGCCGGCATTCCTCCTCGGCTCCGTGCGGGGT
+
CCCFFDFFHGHHHJJJJJJJJJJJJJJJIIIJIJJJJIJJJJJJJJJJJJHHFDDDDDDDDDDDDDDDD?BDDDDDDDDDEDDDDDDDDDDDD########
@8IN
CCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACACAGAAGAGTGACACCCGCCTCTGAGACCCTAGAAGACCCTTGCA
+
CCCFFFFFHHHHHJJIIJJJJIJJJJJJJJJHJJJJJJJJJIFHIIJJJJIIJJHHFFDEEEEDDACDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDC
@8IO
TGCCCACACCCGCAGGGCAGCCCAGGGCTTCGCCAGGCAGACCCTGCAGGGGTGCTCCTCCGCAGGCTTCCTTAGGGATTGCACCAGGAGGCGAAGTGGCC
+
CCCFFFFFGHHHHJJJJJIJJJJGIJJJIJIIJJGJJFIHCHIHGHHFFDFCA@DDDDDDDDDBBD>BDDDDDDCDDCCDDDCDDBDD?@BBD@BB8AD@@
@8IP
CTGGCACGGGGGTGCCCACACCCGCAGGGCAGCCCAGGGCTTCGCCAGGCAGACCCTGCAGGGGTGCTCCTCCGCAGGCTTCCTTAGGGATTGCACCAGGA
+
?<?D?DDDHFHH::DBHIIIIIEHIIHFEEEEC==BBBB@9A5=@B?7?AAB<ABBCCBC>A7;8>?@CC>ACBB@<BB<CCCCCC@CBC?CCCCCCBBB<
@8IQ
GGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACACAGAAGAGTGACACCCGCCTCTGAGACCCTAGAAGACCCTTGCAGGACAGAGTCCCAGCA
+
BC@FFFFFHHHGHIIFHHHGHIHIFGHJCGBFGIJIIGIJGGGHEIIEGCCCEHGDFBCB@BDDCCCCBDDDDDDDDDDBDDCACCABDCD?C:@@C>A?3
@8IR
GTGCCATCTGCTGGCACGGGGGTGCCCACACCCGCAGGGCAGCCCAGGGCTTCGCCAGGCAGACCCTGCAGGGGTGCTCCTCCGCAGGCTTCCTTAGGGAT
+
CCCFFFFFHHHHHJJIJJJJIJFHIIJJJIJJJHHFFDDBBDDDDDDCDDDDDDDDBDDDDDDDDDDDDDCDBB<9@DDDDDDDDDDDDDDDDDDCCCDCD
@8IS
GGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACACAGAAGAGTGACACCCGCCTCTGAGACCCTAGAAGACC
+
@??DDDDDHDHHHGGGJJIIIEHDE=GFHGGGIHHIGDGGGFGGGJEGBDEFH;AHHBHEDCDDCBDCCCBA@@>>@@B<>B>@CDDDDDDDCCCDD@>?C
@8IT
CCGTGTCCTTACCGTGACGTCCACCGACACAGAAGAGTGACACCCGCCTCTGAGACCCTAGAAGACCCTTGCAGGACAGAGTCCCAGCACAAAGCGGAGAC
+
@@@DDDDFHDHHDHEDGIGIID?ECHIIIGGGGGGIEDHGEEHGGFB>AEE=CE?BBFDE;AC;?A?BCCCCCCB8ACBCC:AAACC?3?CB#########
@8IU
CTGAGTGCCATCTGCTGGCACGGGGGTGCCCACACCCGCAGGGCAGCCCAGGGCTTCGCCAGGCAGACCCTGCAGGGGTGCTCCTCCGCAGGCCTCCTTAG
+
@B@FFDFFHHHHHJJJHIJJJIJJJJDBHIJIIIJHHADCCDDDBDDDDDAB@B?BDDDD87AB18??AB9+8?###########################
@8IV
GGGTCTGAGTGCCATCTGCTGGCACGGGGGTGCCCACACCCGCAGGGCAGCCCAGGGCTTCGCCAGGCAGACCCTGCAGGGGTGCTCCTCCGCAGGCTTCC
+
BBCDDFFFHHHHHJJJJIJJHIIIJJJJIJFHGIJIJFHHFFDCDDDDDDBADDDDDDDDDDDDBDDDDDDDDDDDBCCD@D@<BCCCDDCDB9@BB1?CC
@8IW
AGGTAAGGGTCTGAGTGCCATCTGCTGGCACGGGGGTGCCCACACCCGCAGGGCAGCCCAGGGCTTCGCCAGGCAGACCCTGCAGGGGTGCTCCTCCGCAG
+
BCCDFFFFHFFHHJJEHIIJIIJEJIGGIJJJIIIJIEHHHHFFFDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDC?>959?ACDDDDDDBB
@8IX
CGGGTAAGGGTCTGAGTGCCATCTGCTGGCACGGGGGTGCCCACACCCGCAGGGCAGCCCAGGGCTTCGCCAGGCAGACCCTGCAGGGGTGCTCCTCCGCA
+
@BCFDDDFGHHHHJJJHGIJJJJJJIJIJJJJJJJJJJGHHFFFFDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDBDDDDDDDDBDD@>BDDDDDDDDB
@8IY
CACAGGTAAGGGTCTGAGTGCCATCTGCTGGCACGGGGGTGCCCACACCCGCAGGGCAGCCCAGGGCTTCGCCAGGCAGACCCTGCAGGGGTGCTCCTCCG
+
@@?DFFBDFHHHHIIFGHE@HIHIEHHIDHEHIGGGDHIGEEDFFFDCCBB9==:=@?<2<8A?D>BDBCDDBDDBAADDD<?<9ACCDD009BCC@CCA3
@8IZ
CACAGGTAAGGGTCTGAGTGCCATCTGCTGGCACGGGGGTGCCCACACCCGCAGGGCAGCCCAGGGCTTCGCCAGGCAGACCCTGCAGGGGTGCTCCTCCG
+
CCCFFFDEHHHHFHIJJJHIJJJJJJJJJHJJJJJJJIJ@EHFFFFDDDDDDDDDDDBDDDDDDDDBDDDDDDDDDDDDDDDBDDDDDB@B9@BDDDDDDB
@8J0
CACAGGTAAGGGTCTGAGTGCCATCTGCTGGCACGGGGGTGCCCACACCCGCAGGGCAGCCCAGGGCTTCGCCAGGCAGACCCTGCAGGGGTGCTCCTCCG
+
CCCFFFDDHHHHDHJJJIIIIJIJJJJIJCFHIJJJJJGBHHFFFFDDDABB@BDDDDDDDDBBBDB?BCBB>B>AB??BB<<CCBC?89@99?@@CC<?<
@8J1
CTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACACAGAAGAGTGACACCCGCCTCTGAGACCCT
+
@C@FFFDFHHAHHJHE@DHGGIGI@GCEHCGHEHIEHIIGGA@GF<B6@FCFDC<@;A1?BB/=BAC@@@88<5>CCCA+:(+:>?B@3>BDC>>A:@@AC
@8J2
CCTGGACCGTGTCCTTACCGTGACGTCCACCGACACAGAAGAGTGACACCCGCCTCTGAGACCCTAGAAGACCCTTGCAGGACAGAGTCCCAGCACAAAGC
+
CCCFFFFFHFFHHIJJJJJJHJJJJIJJIJJJIIIIFGJJJIJ=FHIJJJHHHFFDEEEEEDDDDDDDDDDDDDCDDDCDDDDDDAC>ACDCCDDDDDD?<
@8J3
GTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACACAGAAGAGTGACACCCGCCTCTGAGACCCTAGAAGACCCTTGCAGGACAGAGTCCCAG
+
@@CFDFFFHHHHHJJJJGHGIIIJJJJJHGDGIEIEEHJIIJJJJIIJEHC=AEDFFFDDDDDDDDDDDDDDDDCCCCDDDDDDDDDDBBDD@CC>CCDCC
@8J4
GGACCGTGTCCNTACCGTGACGTCCACCGACACAGAAGAGTGACACCCGCCTCTGAGACCCTAGAAGACCCTTGCAGGACAGAGTCCCAGCACAAAGCGGA
+
@C@DFFDFHGF#2AEGHEHAGIHHCGHGGHIIIIJG@HII8@4=CHCB:BDFBCCDCAEDDDC3>>C?C,9<3?:(:ABDCDCCA:>C>CA?BCBACDBD>
@8J5
GTTGGGGCTGTGCTCTCAGGAGCAGAGGTGTGTGCACAGGTAAGGGTCTGAGTGCCATCTGCTGGCACGGGGGTGCCCACACCCGCAGGGCAGCCCAGGGC
+
CCCFFFFFHHHHFHIIJJJJGIJIIIII?DCFHHIIIJII3BDHGGHIIJJIJGIIJJIHJJJGHGHFFFCDB9<BCDDDDDB<<B->BD@@>BDDB<@BB
@8J6
CTGGACCGTGTCCTTACCGTGACGTCCACCGACACAGAAGAGTGACACCCGCCTCTGAGACCCTAGAAGACCCTTGCAGGACAGAGTCCCAGCACAAAGCG
+
CCCFFFFFHHHHHJJJJJJGICHIHJJGJJJIJJJJJJJIJJ@DHHJJJJHGFFFEEEDDEDDDDCDDDDDDDDDDDDDDBDDDCD@CDDDDDDDDDACDD
@8J7
CCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACACAGAAGAGTGACACCCGCCTCTGAGACCCTAGAAGACCCT
+
BC@FFFFFHHHHHJJJIJBGHGIIGGIJIIIIIIJ?FHIIJJJJJJGIIJGHIJJJGHGFDDAAC;CDD>CDCCC@BDBBDDCDADCD?ACC?:CDCDCAA
@8J8
GAGGACTCAGGGTCATGGCCCTGCCAGCCACCAGGTGGTTGGTTGGGGCTGTGCTCTCAGGAGCAGAGGTGTGTGCACAGGTAAGGGTCTGAGTGCCATCT
+
CCCFFFFFHGHHHIIHIJIJJJJJJJJJJJJJIJJ?GHFGGHFFIIJJJJHHHHHHHHFFFFFDDEDDD;ACD?A>@CDDD>@ACCD8ACDCDACDDCCDC
@8J9
CCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACACAGAAGAGTGACACCCGCCTCTGAGACCCTAGAAGACCCT
+
@@@DDADDHGHHHFDIEHI;GG;?CC=FGCAHEGBHGDFFHEHC;6-=C5;;85@ECEHFCCCCAA?>AACACCC@@BBBBBC>:>>@B@9?CCCCC99<?
@8JA
GCCACTTCTTCCTGAGGACTCAGGGTCATGGCCCTGCCAGCCACCAGGTGGTTGGTTGGGGCTGTGCTCTCAGGAGCAGAGGTGTGTGCACAGGTAAGGGT
+
CCCFFFFFHGHGHIIIGHIIIJIIJFBGIJIJGIIJJI@FBFHHICHG?EF;BEH5@GIHGF>CCEEC>>CDCC>@DDDCDD(<>BDD>>@>CD@:AC@A2
@8JB
TTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACACAGAAGAGTGACACCCGCCTCTGAGACCCTAGAAGACCCTTGCAGG
+
CCCFFFFFHHHHHGGGIIIJJJFGGIJEG0C?GGIJIIJGGGGIGG;FCH@GHFEFFFEDC@>5>C>AC@D@BD<>@@CD>>@BDC<ACDDACDC?<:::8
@8JC
TTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACACAGAAGAGTGACACCCGCCTCTGAGACCCTAGAAGACCCTTGCAGG
+
CCCFFFFFHGHHGEHIJIJIIJIJJIJJJIGIIJIIIIJIGE7@FHI=GCCGGHGFFFEDECD>ACDCDBDDB@BBDDDDCDDDDCCDDDDCCDCDCDDCA
@8JD
CGCTCCTCGAGGAGCTGGCCATTTGGCCTGCAGCCACTTCTTCCTGAGGACTCAGGGTCATGGCCCTGCCAGCCACCAGGTGGTTGGTTGGGGCTGTGCTC
+
C@@FFFEFHHHDHEHJGIIHGHIJEHGI@HIJEIJIJHGGIIEHG@HIBCB@FHCGHGGCGHFGHCEFEFEEDDD?=A=8,>?;BBDDDB0<@BB<1?C@A
@8JE
CAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACACAGAAGAGTGACACCCGCCTCTGAGACCCTAGAA
+
@@<DFFF?FDHFHEIEHBHIEHHGEBFH;FFDHGEGGGIGIFHAFGIIFCFGC;5CEHFFFDEBCDDBCDCCAAA>C>A@CDB59B@@@(4:>@BDDC?@@
@8JF
GTCTCCTTGGTGGGGGTGCCCTTTTGCTGGTGGCGCCATCAGATACATCAAATTCTAGTTTTACAGGTCCGCTCCTCGAGGAGCTGGCCATTTGGCCTGCA
+
C@@FFFFFHGDHHIJI:DFGIGJJJIJJIIEGGFHIIGGHIHFHFHHHFDBDFFCEEC>CEECDCCCCDDDDDDDCDDDB<BDDBDCDDDDDEC3@C@8A<
@8JG
CTGGACCGTGTCCTTACCGTGACGTCCACCGACACAGAAGAGTGACACCCGCCTCTGAGACCCTAGAAGACCCTTGCAGGACAGAGTCCCAGCACAAAGCG
+
CCCFFFFFHHHHHJJJJJJIJJJIJJIJJJJJIGGIHGIGGI@FGGGHIIFHFFFEEEEEEDDDDDDDDDDDDDDDDDDDDDDDDDCCDDDCBDDDD?CCB
@8JH
CAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACACAGAAGAGTGACACCCGCCTCTGAGACCCTAGAA
+
@@@DDDD=FFHGFGGGHGGGIIIGHFFCBGIHII>BAAA9D0B==DDEDHAGECGHEHEDB>B>A:@=CB>>CD?:@CCCA<>-5@@@::>4:>BACC?>@
@8JI
CCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACACAGAAGAGTGACACCCGCCTCTGAGACCCTAGAAGACCCTT
+
CCCFFFFFHHHHHJJJJJHIJJJJJJJJIJIJJJFHFGHIIIJJJGIIIIIIIJJJHHFFDEECDDDDCDDDDDDDDDDDDDDDDDCDDDDDDCCDDDD@C
@8JJ
CGTCCTCCTCCACCTCCTGCGGGGCCTTTTGCTGCCTCACTGCTGCTTTCCTCAAGGGAGGCTTGAGGCCGGACCTCTCTCCCAGTCTCCTTGGTGGGCGT
+
CCCFFFFFGHHHHJJJJJJJJJJJJJJJJJJJJIIJJJIIHHHHHHFFFFFFEEEDEDDDDDDDDDDDDDDDDBDDDDDDDDD?CDCDDDDDDDC?BD@B5
@8JK
CTCCTACCGTCGTCCTCCTCCACCTCCTGCGGGGCCTTTTGCTGCCTCACTGCTGCTTTCCTCAAGGGAGGCTTGAGGCCGGACCTCTCTCCCAGTCTCCT
+
@@@BBDDBFDAAHGGDFHIGGAEC>:DGI?@DD;BEH>CCBE;;@;(;>BACCCCA35,:AC:A>:((2&5?2958AC0(09-&)3:@9@A>><AC::>:@
@8JL
AGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACACAGAAGAGTGACACCCGCCTCTGAGACCCTAGAAGACCCTTGCAGGACAGAGT
+
CCCFFFDDH=FHGIJJJIIIIJEHGGGIJJFJI;BCGHCBGDHIGFGJFGEGHFFF?@CEEED>9?=BDCDDDCDDDDDDDDDD?CAC>ADCCDDA?@CC4
@8JM
CTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACACAGAAGAGTGACACCCGCCTCTGAGACCCTAGAAGACCCTTGCAG
+
BCCFFFFFGHHGHIEHIHJJGIJJJJJIJJFGHIJJJJJJIJJ=FHCHHIGHIIHFFFDDEDCD>CCCDDDDDDDBBCDCCDDDDCDDDD>?CCDCCCCCD
@8JN
CGTGTCCTTACCGTGACGTCCACCGACACAGAAGAGTGACACCCGCCTCTGAGACCCTAGAAGACCCTTGCAGGACAGAGTCCCAGCACAAAGCGGAGACT
+
@@@DDDDFHFHFHIIIJIG8FHIIJII>EHHHIC@G9BGGIIIJIJBGHCAEHEHFFFDDA@CCACD?CDCD@??A??>AC4>@@CB?B??<ACB@<@5?C
@8JO
CCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACACAGAAGAGTGACACCCGCCTCTGAGACCCTAGA
+
CC@DFFFFHHHHHJJJGIIJJJIBHIEEGDGGGIIBEEGEIGHEGIJBGHFC<;CEEHEDB??A9A@BB?BC>CCD(:3:@C7<BB505@3>@CD?A9?CC
@8JP
TGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACACAGAAGAGTGACACCCGCCTCTGCGACCCTAGAAGACCCTTGCAAGACAGAGTCCC
+
????DBDDDCDD8EEID+C<+:?4?EE?9C1?DDDDDID98<A@ADDID)=7..;))7;>??>??####################################
@8JQ
CTGACAAGGACCTGTCGGACCTGGTGTCTGAGATGGAGATGATGAAGATGATCGGGAAACACAAAAACATCATCAACCTGCTGGGCGCCTGCACGCAGGGC
+
@@@DFFFFGDHHDGGGJJIJJJGHFFDDCFFHHIIIIICHIGGHGDGG4B=FHGHIIGIGFEEFFFFDCACEEDDDDDCDDCCABADDDDA8<CDDBB>90
@8JR
TAGGGTCTCAGAGGCGGGTGTCACTCTTCTGTGTCGGTGGACGTCACGGTAAGGACACGGTCCAGGTCCTCCACCAGCTGCTTGAACGTGGGCCTCTGGGG
+
@@@DDBDDFFFFFFGE8A07;=8B=@)8==).))74:';=(),'3;;33,5<3>:9@?5@0873(++(4>3>@BB@8<:49:@##################
@8JS
GGACAACGTGATGAAGATCGCAGACTTCGGGCTGGCCCGGGACGTGCACAACCTCGACTACTACAAGAAGACAACCAACGGCCGGCTGCCCGTGAAGTGGA
+
CC@DFFFFHHHHHJJGIHIEIJIJJJJJJJGIIIJIJJJIJEHHHFFFEEACDEDDBDDDDDDCCDDDDCDDDCBDDA@BBDDBBDBB?BDB9@BBA@CDA
@8JT
CTGAGGCCTTGTTTGACCGAGTCTACACTCACCAGAGTGACGTCTGGTCCTTTGGGGTCCTGCTCTGGGAGATCTTCACGCTGGGGGGCTCCCCGTACCCC
+
CCCFFFFFHHHHHJIJJJJJJIJJJJJJJJJJIJJJJEHIJJJJJJJJJJIIJJJJJIHHHHFFFFFFDEDBDDEDEEDDDDDDDDDDDDDDDDDDDDDDD
@8JU
ACCGAGTCTACACTCACCAGAGTGACGTCTGGTCCTTTGGGGTCCTGCTCTGGGAGATCTTCACGCTGGGGGGCTCCCCGTACCCCGGCATCCCTGTGGAG
+
<B?DFFDDHHHHHJIGGHJIJJHGIIJEGGIIIIJIJIJJJJIIJIDHJJIGIDCFGGIJJJHHHHFFDDCBDDDDDDDDBBDB@?BDDDDDDDCCCCCDD
@8JV
TCTACACTCACCAGAGTGACGTCTGGTCCTTTGGGGTCCTGCTCTGGGAGATCTTCACGCTGGGGGGCTCCCCGTACCCCGGCATCCCTGTGGAGGAGCTC
+
@@@FFFFFHDHHHJJIFFHHIIIJJJHIIIJJJIIJFHGJJJJJJJJIGIGCFHIIIIJIJHHHFDDDDDBBDDBB?BDBDDBDDDDDDD@CDCBDDDDDD
@8JW
CGTCTGGTCCTTTGGGGTCCTGCTCTGGGAGATCTTCACGCTGGGGGGCTCCCCGTACCCCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGG
+
CCBFFFFFHHHHHJJJJIJJIJJJJJJJJJJIJJJJJJJJJIJJJJJDDDBDDDDDDDDDDDDDDDDDDDDDDDDDDBDDDDDDDEDDDDDDDDDDDDDDD
@8JX
CTCAGAGGCGGGTGTCACTCTTCTGTGTCGGTGGACGTCACGGTAAGGGCACGGTCCAGGTCCTCCACCAGCTGCTTGAAGGTGGGCCTCTGGGAGGGCGC
+
=>>AAAAACCCA4A4>BA?>AB4=)9=>A<A5=A=>@<<5=3;(5=9>(888;:28:=?=:??8;?###################################
@8JY
CTCAGAGGCGGGTGTCACTCTTCTGTGTCGGGGGACGTCACGGTAAGGACACGGTCCAGGTCCTCCACCAGCTGCTTGAAGGTGGGCCTCTGGGAGGGCGC
+
@@@DDDDDFFFF0?7?BD@==C==888=;@E':>''7&0?<06(2?3>389209+8:A@@+3@>@B(9?218:@?(>48A>A###################
@8JZ
GTACCCCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGC
+
CC@FFFFFHHHGHJJIJHIJJJJIJJIIJJJGGIJJJJJJJJJJIIIJGIEHHHFFFDDEEEDDDDDDDDBDDDDDDCCDDDDDDDDDDCDEEDDDDEDDA
@8K0
CCCCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGG
+
@@@F1ADFGHHHFHHHIGJGGIHIIIIIIJJIIJIFJJJIJIIIFIJIIGEEFHFFFFFDEDDDBDDDDDCDDDDDDDDDDDDDDDDCECCDDDEDDCB@B
@8K1
CTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGTGTCACTCTTCTGTGTCGGTGGACGTCACGGTAAGGACACGGTCCAGGTCCTCCACCAGCTG
+
CCCFFFFFHGHHHJJJEGIJJJIGGIGHIIJJJJJJJJG5=9?BDFCCEE;(5>@>6?;@;,:=)08<79+8?C@3(9?<@(894:A44@ACC<<A8284:
@8K2
CTCAGAGGCGGGTGTCACTCTTCTGTGTCGGTGGACGTCACGGTAAGGACACGGTCCAGGTCCTCCACCAGCTGCTTGAAGGTGGGCCTCTGGGAGGGCGC
+
CCCFFFFFHHHH?@?BFHEBFHBB@==@@FH4?E6=?59=?9>5;?@C:99<;B2<@@@C3:ACCC??B28<4>?:A4+>>C3:@@(82<::>C28@B###
@8K3
CAAGGGTCTTCTAGGGTCTCAGAGGCGGGTGTCACTCTTCTGTGTCGGTGGACGTCACGGTAAGGACACGGTCCAGGGCCTCCACCAGCTGCTTGAAGGTG
+
CCCFFFBDFHHHGJJJAFGIHJIJIJJJE5;47=C7=?E7=7?>;;=A9?>(;;88888<(2<>A:<<<>@(8;>:A&8??BD??B28A@CACA:(4@A9>
@8K4
TGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGTGTCACTCTTCTGTGTCGGTGGACGTCACGGTAAGGACACGGTCCAGGGCCTCCACC
+
@BCFFFFFHHHHHJJJJJJJJGHJJJJJJJJGHIJJJJJJIJJE'93;;>C;>C;>(55::;@3<@148052<0<(2<:A:(3209(2<4:C&2<<<B3?B
@8K5
CCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAG
+
CCCFFFFFHHHHHJJIJJIJJJJJJJJIIJJJIJJJJIJJJIJJJJJJJIHGIHGHHHFFFFDDDD@DDDDDDDDDDDDDDDDDDDEEDDDDEDDDDDDDD
@8K6
CTCAGAGGCGGGTGTCACTCTTCTGTGTCGGTGGACGTCACGGGAAGGACACGGTCCAGGTCCTCCACCAGCTGCTTGAAGGTGGGCCTCTGGGAGGGCGG
+
@@@DDDDDFFFF??78B?D@DF88)878@FE-5=;759<?;,9',88@?(5579<<6>:?>:>>>AB<?188:@>@B3(+>A93?>782243:?(8<B###
@8K7
CTCAGAGGCGGGTGTCACTCTTCTGTGTCGGTGGACGTCACGGGAAGGACACGGTCCAGGTCCTCCACCAGCTGCTTGAAGGTGGGGCTCTGGGAGGGCGC
+
???DDDDDDDDD8@?DDE@BBD8=8=@=>AD/;A6?<5<@@>?'3;(8((955<28<>>=+3>A>A9<?<884>>:>:2>4>3:>?&05<>:A?+8>?###
@8K8
GGCGGGTGTCACTCTTCTGTGTCGGTGGACGTCACGGTAAGGACACGGTCCAGGTCCTCCACCAGCTGCTTGAAGGTGGGCCTCTGGGAGGGCGCGGCATG
+
CCCFFFADHHGHHJJJJIIGIIJIJFHIGJJIJJJJJ@CHFHGFFFDDAD?CDDCCDDDDDDDDDDDDCDDDBDCD?CDB<ABBDDDDABDD@DBDDB<@B
@8K9
CCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAG
+
CCCFFFFFHHHHHIJJJJIJJJJJJJJJJJJIJIJJIJJGJJJIIJJJJJIJJHHHHHFFFFDDDDDDDDDDDDDDDDDDDDDDDDEEDDCDEDCDDBDDD
@8KA
TGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGTGTCACTCTTCTGTGTCGGTGGACGTCACGGTAAGGACACGGTCCAGGGCCTCCACC
+
BCCFDFFFHHHHGGIJJJIJJCFHIIIIGJJFHEIJJIJJJJJB,9,(6>>;>CA@:>;:>=B258(:;&5<<9>22?>@+2(2)52<@3(9&(+28ACC8
@8KB
GGCGGGTGTCACTCTTCTGTGTCGGTGGACGTCACGGTAAGGACACGGTCCAGGTCCTCCACCAGCTGCTTGAAGGTGGGCCTCTGGGAGGGCGCGGCATG
+
@@@DDD:DCFDHFIIIIBHDGGG@A??DGFH<BGHIIC?ECHHDDDBC;?;ACCCCCCCCCCBB9A>:A@CCB@CC9@897?BB@>C<8?<<309>B@BBA
@8KC
GGCGGGTGTCACTCTTCTGTGTCGGTGGACGTCACGGTAAGGACACGGTCCAGGTCCTCCACCAGCTGCTTGAAGGTGGGCCTCTGGGAGGGCGCGGCATG
+
CCCFFFDDFHDHHIJJJJJHIJJJJ@FICGIGHCHIJ;EHFHHFFFCDCDBDDDDDDDDDDDDDDDDCCDDDBDDDCCDDDDDDDDDD?BDDBDDDDD><B
@8KD
CTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGTGTCACTCTTCTGTGTCGGTGGACGTCACGGTAAGGACACGGTCCAGGTCCTCCACCAGCTGCT
+
CCCFFFDFHHHHHJGHIJJJIJJJGHIIIGGIIFIJJ5-5;;>B7>@>>;;;>;>B25=9>@-5?@7>+8?CC:13<<B8<BC>A3:@>AC3?B#######
@8KE
CTCAGAGGCGGGTGTCACTCTTCTGTGTCGGTGGACGTCACGGTAAGGACACGGTCCAGGTCCTCCACCAGCTGCTTGAAGGTGGGCCTCTGGGAGGGCGC
+
CCCFFFFFHHHH?D@FEGEFCGBGCFAFEBH;CH9?B<ACCAB5=@>C@99?=B8<@AAC:>AA:A(9A<8A>CCCA:8>:C3>BB0<?AA>CC1<BB<B5
@8KF
CGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGT
+
@CCFFFFFHHHHHJJJJGJJJJJJJIJJJIJJJJJJIIGIJJJJJJJJJIJJJIJHHHHFFFDDDDDDDDDDCDDDDDDDDDDDDEEDDDDECDDDDB@B2
@8KG
CGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGT
+
CCCFDFFFHHHHHIIIJJIJJJIJJEIIIJJJJJIJJJCIIIJJIJJIJJDIIIIHHHHFFFDDDDDDDDDDCDDDDDDDDDDDDEEDDDDEA@CB@@D@8
@8KH
CTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGTGTCACTCTTCTGTGTCGGTGGACGTCACGGTAAGGACACGGTCCAGGTCCTCCACCAGCTGCT
+
CCCFFFFFHHHGHJCGIIJJIJJIEHHIJJIHIFIJI;A??CCB?;A6;6;;;58?88=(5805<?05(2<:A429(&5(29>>C(:@@@CC?BB######
@8KI
CTTCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCT
+
CCCFFFFFHHHHHJJJJJJJJJJJHJJJJJJJJJJJJJJJIIJIJIJIJJJIIJJIGHHFFDDDDDDDDDDDDDDDDDDDDDEEDDDDEDDDBBDDD?BDA
@8KJ
CTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCAT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJIJIJJJJJJJJJJJJJJJIJJHHFFDDEEEDDDDDDDDDDDDCDDEEDDDDEDDDDDDDD?BDEDDDDC
@8KK
GGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJJJJHHFFFFFEEEEDDDDDDDDCDDEEDDDDEDDDDDDDD@DDEDDDDDDDD@
@8KL
GAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJIJIJJJJJGIIIIIJGIJJJIGFHFFFFFEEEDDDDDDDDDDDFEDDDDEDDDDDDBD?BDEDDDCDDDDD>
@8KM
GAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGC
+
CCCFFFFFHHHHHIJJJJJJJJJIJJJJJJJJIJJJJJJJJJJIIGHIJJIHGFFFFFECEDDDDDDDDDDDFFDDDDEDDCDDDDD?BDEDDDDDDCDDB
@8KN
GAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGC
+
C@CFFFFFHHHHHJJIIJJJJJJJIJJIJIJIJIEIIJJJJIIIHGIJGIJHHFFEEFEEEDDDDDDDDDDDEDDDDDEDD@BBDDB??CDDDDDDDDD<<
@8KO
GGCGGGTGTCACTCTTCTGTGTCGGTGGACGTCACGGTAAGGACACGGTCCAGGTCCTCCACCAGCTGCTTGAAGGTGGGCCTCTGGGAGGGCGCGGCATG
+
CCCFFF@DFHHHHJJJJJJIIJJJJDHIHIJJJJJJI@EHEHEB)6>CAB;CCDCDDDDDDCDBDBDDDDDCDDDDCDDDBDDDDDD?ABDD>B9@B<99?
@8KP
TGGGTCTCAGAGGCGGGTGTCACTCTTCTGTGTCGGGGGACGTCACGGTAAGGACACGGTCCAGGTCCTCCACCAGCTGCTTGAAGGTGGGCCTCTGGGAG
+
@@@DDDDDFFFFFIIIG)7788B<=AF4=)877)'='4;/;000+857(28(998??-5+8<(3<44>@AB<@B2(+:>A::42>>?##############
@8KQ
GCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCT
+
@CCFADFDHHHGHJJJJJBGIJJJJIGJJGIJIJIIJIJJIGIIIIDGJHHHGFFFFFDDD@DDACDFEDDDCDCCCBBBDD<ACCCDDDDDDD@<@BDD<
@8KR
CGGGTCTCAGAGGCGGGTGTCACTCTTCTGTGTCGGTGGACGTCACGGTAAGGACACGGTCCAGGTCCTCCACCAGCTGCTTGAAGGTGGGCCTCTGGGGG
+
@CCFDFFFHHHHHIIII.<;=BFEC@F;7=77==<B-;?.;>3;BB>B5<<5>(5985<2<@:>C+:@>>A9<A(+2449>C:(>4?(4?<(82<>3:?##
@8KS
CTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCC
+
CCCFFFFFHHHHHJJIIJIIIJJJJJJJJJJJIJJJIJJJJJJIJJJJJHHHHFFFDDDDDDDDFFDDDDEDDDDDDDDBDDDDDDDDBDDBDD@BDDDDD
@8KT
CTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCC
+
CCCFFFFFDHFFHGHGIIJJJIGHGEGGJHIDHIIIHJJJIJJJIIJIBHHEEBDEBBDDDDDCCDDDDDEDDCB>B>B@BCCCCDCCDDCBDB@@BDBDB
@8KU
TTCTAGGGTCTCAGAGGCGGGTGTCACTCTTCTGTGTCGGGGGACGTCACGGTAAGGACACGGGCCAGGTCCTCCACCAGCTGCTTGAAGGTGGGCCTCTG
+
@@@DDDDDFFFFFIIIIIIIF.77=@D@ACE=@@@C7>=E'3;)-5)58?7:(2<:>:<??;@&5;22?(4>@>?9<?(224@A>>32@############
@8KV
CTGGGTCTCAGGGGCGGGTGTCACTCTTCTGTGTCGGTGGACGTCACGGTAAGGACACGGTCCAGGTCCTCCACCAGCTGCTTGAAGGTGGGGCTCTGGGG
+
???DDDDDDEF2<CDEDI'557.?@;;?.;(6.6.3;'5;((3880<5<(8<>>32<20;28<A>?4:>(:999>>1<>>A:A(2AAA#############
@8KW
CTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCC
+
@CCDFDFDHHHFB@AEG?EFGGHJGCGGHBHIIGCCHIFHHBGHGGGGGEEEHDFFCBDDCA5:>CCCDCDCCA@9>5<8<ADCCDCDBCDBB>.599ADB
@8KX
CGGGTCTCAGAGGCGGGTGTCACTCTTCTGTGTCGGGGGACGTCACGGTAAGGACACGGTCCAGGTCCTCCACCAGCTGCTTGAAGGTGGGCCTCTGGGAG
+
@@@DBDDDHHHFHIIII7@;<8CC@;=7=)777;8<'9;2-55@225:+8<+9+2??8<227+3?4:@:>C(3<8224>C>C3+4:?+:@B@#########
@8KY
CTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCC
+
CCCFFFFDHFDHHIJIGGIIGEGGGGGGHGIIEDFHA=FH@GGHIGGIIHHFHFFDDDDDDDDDFEDCDDDDDDDDB>@BDDDDDBCCBAC>9<5<B@DDD
@8KZ
CTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJIIJJJJJJJJJJJJJJJJHHHDDDEEEDFEDDDDEDDDDDDDDBDDEDDDDDDDDDDDDDDDDDDDD?A?BD
@8L0
TGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGTCACTCTTCTGTGTCGGTGGACGTCACGGTAAGGACACGGTCCAGGTCCTCCACC
+
CCCFFFFFHHHHHJJJJJJJJCFHIIJIJJJFHIIJJGIJIJJH/5)02>999@::::>@@7<&8>2>509<@;B2?@>C>8380<+89>:C+4>:@C9<B
@8L1
GCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCA
+
@<@<D3=B;FF)0<;FDFIAFFIFGDGF=FG)0((--BFCC@D@5;AEBB@@(6..6>>AB3@A@@@8;>214:@383:?::5&059<@(8?3:8?@0<?8
@8L2
CAAGGGTCTTCTAGGGTCTCAGAGGCGGGTGTCACTCTTCTGTGTCGGTGGACGTCACGGTAAGGACACGGGCCAGGGCCTCCACCAGCTGCGTGAAGGTG
+
CC@FFF=BFFDHDBHEFHIGHHGGIGIIH/--.74?A;A3=B@C).9A319((3,,(58;28?AC>?CD>5&09?8?&+28<<?(228<C@?#########
@8L3
CTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGTCACTCTTCTGTGTCGGTGGACGTCACGGTAAGGACACGGTCCAGGTCCTCCACCAGCCG
+
CCCFFFFFHHHHHJJJGHIJJJJJJJHHIJJJJJJJJJJ/;008>CC8C>939>3357)85(+000<?7@+8?3>(8<<&9(29::?++:@@C9?A#####
@8L4
TGAAGGAGGGCCACCGCATGGACGAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACC
+
@@?BDFDDDFHDFHGDGGGCCHGEIIIIGEBHIIICHGEHGC5AD?BBBCCCCCDCCCCECCCCB>BB@BCCCCBCCCCCBB<<@9@BB@CCBBCBBBBB@
@8L5
TGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACC
+
CCCFFFFFHHGHHJJJJJJJJJJJJJIJJJJJJJJJJJIJGIJJJGHFFFEEEFFEEDDEDDDDDDDDBDDEDDDDDDDDDBDDDDDDDDDCBBDBDDDDD
@8L6
GAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCT
+
CCCFFFFFHHHHHJJJJJJJJJJJIJJJJJJJJJJJJJJIJJJIHHFFFFCEFEEEEEEDDDDDDDDDDDEDDDDDDDDDDDDDDDDDDDDDDDDDDDDDD
@8L7
CTCAGAGGCGGGTGTCACTCTTCTGTGTCGGTGGACGTCCCGGTAAGGACACGGTCCAGGTCCTCCACCAGCTGCTTGAAGGTGGGCCTCTGGGAGGGGGC
+
@@@DDDDDFFFF8?7B?D@88C8====8;4@'5B2799=(3;@'2<(>:9,55528<>>?3+:@:???@B??4:>@A3+>:A###################
@8L8
CTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGTGTCACTCTTCTGTGTCGGTGGACGTCACGGTAAGGACACGGGCCAGGTCCTCCACCAGCTGCT
+
CCCFFFFFHHHHHJCFIJJJJJIJHIJJIJIJJJIJI4=4;;?;7;C;;;>;;;8>,8;5:=)5??@;(2?@C48?A9B&5><?B4:A@>C<CD?<A>>>@
@8L9
CCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGC
+
CCCFFFFD?FHCHGIIIIIBHIIIIIGH@GCFAFGHIIEEEHIIICHIIGHHBH<ABC?BCDA@BCC9@AB9>9@BBCCCCC@?B8@@B@@BCC:ACCBCB
@8LA
GGCGGGTGTCACTCTTCTGTGTCGGTGGACGTCACGGTAAGGACACGGTCCAGGTCCTCCACCAGCTGCTTGAAGGTGGGCCCCCGCGGGGGCGCGGCCTG
+
@@@DB6?D?FFF4BF@FB<BFFE>B8178BF6@1@B'5=CAEFD>?<>5?;>A?-5::>?9?B?#####################################
@8LB
TGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGTGTCACTCTTCTGTGTCGGTGGACGTCACGGTAAGGACACGGTCCAGGTCCTCCACCAGCTGCTTGAAGG
+
CCCFFFFFFHHHHJJJJJJJJJJJJJJJJJI-;;A=A>AAD@@3;??><A9=B9@==BBBBB0<@@CA@CA;B2?B>>C4:CACC9AB28<:@C>C@8CCD
@8LC
GGCGGGTGTCACTCTTCTGTGTCGGTGGACGTCACGGTAAGGACACGGTCCAGGTCCTCCACCAGCTGCTTGAAGGTGGGCCTCTGGGAGGGCGCGGCATG
+
@@@FFF<ACFADAAEGEIDFDFHII8DHGE;<@FH;A;AACC;;BEDCCB9>;A>>A>@C9CA?<BCC?:>A8>A>+:?>BA@B>@CD1<<@<55>B####
@8LD
GACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGA
+
C@@FFFDFHHHHDIIJIJIIJJJIJGIJJIIJJJIJIJJJJJDGIGHF?BBDEEDEDECDDDBDDDDDDDCAB@B@DBDDDDDDCDDDDDBCDDCCB?A##
@8LE
GCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGG
+
C@@FFFFFHHHHHJJIJIJJJJJJJJJJJJJIJJJJJJIJIJJGHIHHHHEFFFFAA@DDBBBDB?AABBDDD?B9B:9A>CAACB?CCACD<A8<?<3?<
@8LF
CTCAGAGGCGGGTGTCACTCTTCTGTGTCGGTGGACGTCACGGTAAGGACACGGTCCAGGTCCTCCACCAGCTGCTTGAAGGTGGGCCTCTGGGAGGGCGC
+
@@@DDDDDFFFF8@@F?DBCFFBFDFCCAAE5?E=AB5==?3>,;?:A599<;@8?@BAB3:@@AB<?B88?:>>>B:2@BB9>@B2<?B@3>B8<BB<B0
@8LG
CCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGAC
+
@@CFFFFFHHHHHGIIIJIIJJJGGJIJJIIJJJJJJIIFHCGHIJJJHHHHHFFDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDACDDDDDDDDDDDD
@8LH
GGCGGGTGTCACTCTTCTGTGTCGGTGGACGTCACGGTAAGGACACGATCCAGGTCCTCCACCAGCTGCTTGAAGGTGGGCCTCTGGGAGGGCGCGGCATG
+
CCCFFF@DDFFHFIIJIJIECFHGI8BHDEIFHGIHG@AHHHFFFFD,.6;ACC>ACDDDDDDDDDDDDDDDBCCD>CDD8?BBDDDD<?9>BDDBDDDBD
@8LI
CGGGTCTCAGAGGCGGGTGTCACTCTTCTGTGTCGGTGGACGTCACGGTAAGGACACGGTCCAGGTCCTCCACCAGCTGCTTGAAGGTGGGCCTCTGGGAG
+
@CCFFFFFHHGHHIIII7@;BFEAC@G;@;==.):A-;B6;>3;??8;(58>@>ACB8B2<<>>C::AA@C99?228>:9>A:8A:?(:?B(8<?:>CC2<
@8LJ
GAGGCGGGTGTCACTCTTCTGTGTCGGTGGACGTCACGGTAAGGACACGGTCCAGGTCCTCCACCAGCTGCTTGAAGGTGGGCCTCTGGGAGGGCGCGGCA
+
@<@FFDFF6??BFHIBDH>GEAFEHII6CBCGEABBBCB1=@CCC?CBBCC?@CCCC@A@CC39ABBBCCCCCCBCACAC@B<A@BC>C=A@@B99<@B90
@8LK
CTCAGAGGCGGGTGTCACTCTTCTGTGTCGGTGGACGTCACGGTAAGGACACGGTCCAGGTCCTCCACCAGCTGCTTGAAGGTGGGCCTCTGGGAGGGCGC
+
???DDDDDDDDD0?7<BD8=BB8=88=87@A';A27<'9;;3>,5=5>55998=28:>>=(3>3>A3<>22<:>A>>(2::>+:>>(8(844>?2<??###
@8LL
CGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACC
+
CCCFFFFFHHHHHIJJJGIIIIHHIJJICFFIIIIGIJEHFGGIGIJJJECEHFDDDDDDDDDDDBBBDDDDDDDDCDCCDCDD@CAC@BDDDBDCCBBDC
@8LM
GGCGGGTGTCACTCTTCTGTGTCGGTGGACGTCACGGTAAGGACACGGTCCAGGTCCTCCACCAGCTGCTTGAAGGTGGGCCTCTGGGAGGGCGCGGCATG
+
CCCFFFADFHDFHJGJGJIGIJJIJDGIEID:AGIJJCEHHHHFFFDDCD@DDDAACDCCDDDDDDCCCCDC@DDDAC@B8?@DDCCC?BD@<BDDD<.9A
@8LN
GGCGGGTGTCACTCTTCTGTGTCGGTGGACGTCACGGTAAGGACACGGTCCAGGTCCTCCACCAGCTGCTTGAAGGTGGGCCTCTGGGAGGGCGCGGCATG
+
???DDDDA:?D?DDEIEB<D<D4?<DADCC<AA=AAD;CDCDAA>;38(;9>A?;5>AA>3=<99<>:A>A:<>:>>>8>????:>><(8>>>>;>?>;>?
@8LO
GTTAGGGTCTCAGAGGCGGGTGTCACTCTTCTGTGTCGGTGGACGTCACGGTAAGGACACGGTCCAGGTCCTCCACCAGCTGCTTGAAGGTGGGCCTCTGG
+
@@@FFFFFHHHGGIIIIIII:F@C@FGEDH@D==@==AE9?D2;98;===8,<@@C@?CB@B2<@A@C4:ACCCCCBB?@CCCCC@8ACC>CBB(80<4:C
@8LP
TGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGAC
+
CCCFFFFFGFHHGIHICHHGGGIIEIDDHIHGGIIJJJJJJEAE?;<BECECEDBDBCCDCDDBDDBDDCCBDDDB<AB<CCCDDC<BB0?BD>BDDDD>@
@8LQ
CTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACACAGAAGAGTGACACCCGCCTCTGAGACCCTAGAAGACCCTTGCAGGACAGAGTCC
+
CCCFFFFFHGHHHJJJJJJJGIJJJJJIJJJIIJJJJJIJJJJIJJJJHHHHHFBDFFFEDBDDDDDDDDDCDDDDDDDDDDDDDDDDDDDDDDDDDDCCD
@8LR
CCCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGTTACTCCTTTGTGTCGGTGGACGT
+
@?@FFFFFHFCFAEECHGAHECGEFHIG?@DGIJJAFHGIG=CAFGG;)=@;6?ECDFEEF@6>CE:C>>?BDDB##########################
@8LS
CAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACACAGAAGAGTGACACCCGCCTCTGAGACCCTAGAA
+
CCCFFFFFHHHHHJJJJJIJJJJJJFGIFHIIJJIJJIJJIHHHIJJJJJJJIJGIHHHFFFFDDDDDDDDDDCA:A@CDABDB>BDDDCCDCCBDDDCDC
@8LT
CTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGTGTCACTCTTCTGTGTCGGTGGACGTCACGG
+
CCCFFFFFHHHHHJJJJJJJJJJHIIJJJIHJJJIIIJJJJJJIJJJFHIGHIJJJHHHHHFFFFFCDDD&55:44:>>C@A###################
@8LU
CAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACACAGAAGAGTGACACCCGCCTCTGAGACCCTAGAA
+
CCCFFFFFHHHHHJJJJIJJJJJJJGHIIJIGIJJJJIIIIGIFHIIGIJHGHIGIHHHEFFFCCDBDDDDDDDDACDDCCBDDBDDDDCCDDDDDDDDDC
@8LV
GTGTCCTTACCGTGACGTCCACCGACACAGAAGAGTGACACCCGCCTCTGAGACCCTAGAAGACCCTTGCAGGACAGAGTCCCAGCACAAAGCGGAGACTC
+
@BBDDFFFHHHHHIIJJJJJIJJJJJJJIIJJJJJBDFHJJJJJJJJIJHHHHHHFFFFEEEEEDDDDDDDDDDDDDDDCDCDCDDDDCDDDDDDBBBBDD
@8LW
ACCGTGTCCTTACCGTGACGTCCACCGACACAGAAGAGTGACACCCGCCTCTGAGACCCTAGAAGACCCTTGCAGGACAGAGCCCCAGCACAAAGCGGAGA
+
???D?DADFFDHFIAG@?AFBEGIGGHII6D;FGGG@C/?<FFHII';@=:77ADCCEECC>A@5??CBC??AAAB@B<29A388<@BBCA??BCC<B###
@8LX
CCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACACAGAAGAGTGACACCCGCCTCTG
+
CCCFFFFFHHHHHIJJJIJJJJJJJJJJJJJIJJIIGIJJJJHIJJJIJJGFBHEFFFFCEEDCDBDDDDDDDDDBDDDCBDDCDB+>CDDDDDBBD@BCC
@8LY
CCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACACAGAAGAGTGACACCCGCCTCTGAGACCCTAGA
+
?@@DDB:=D=<D?<C<+:AD8FCGE;:CAFCFFFD;;DCFF<@FFIB>@FF@;-65-5?>?5@(39;9=@@BB>ABB@3>>A209@95@BB33:@??@33@
@8LZ
CCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACACAGAAGAGTGACACCCGCCTCTGAGACCCTAGA
+
@CCFFFFDDBF=FHGGIJJJJJJIGIFHIGHG?FHAGGGIGHHHHHHIIGHGGAGHEAEDFFFBCDDBDCBD@A><:>CCCD?@DBBDDDDCCCA<A???C
@8M0
CTTACCGTGACGTCCACCGACACAGAAGAGTGACACCCGCCTCTGAGACCCTAGAAGACCCTTGCAGGACAGAGTCCCAGCACAAAGCGGAGACTCCGCAC
+
CCCFFFFFHHHHHJJJJJJJJIJJFIJJJJ?GGGCHJJIIJJJGGJJIJHEHHFFFFFEDDEEDDDDDDDDDDDCDDDCCBDDD?BDDBBDDDD<CCBDDD
@8M1
CTCAGAGGCGGGTGTCACTCTTCTGTGTCGGTGGACGTCACGGTAAGGACACGGTCCAGGTCCTCCACCAGCTGCTTGAAGGTGGGCCTCTGGGAGGGCGC
+
DDDDDDDDDDDDDDCC@DDDDDDDDDDBDDDDDDDDDDDFFFFHHHHHHJIJJJJJJJJIIJJJJIHJJJJJJJJJJJJJJJJJJJJJHHHHHFFFFFCCC
@8M2
CTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGGCACTCTTCTGTGTCGGGGGGCGC
+
@@@DDDDDFHDDHIGEE?EEGGHIIGIEGDHIEEGEGGBDDBAFCFG@@C@C?CCEHFDFDFBCECEDEDDDBDD##########################
@8M3
GTCTCAGAGGCGGGTGTCACTCTTCTGTGTCGGTGGACGTCACGGGAAGGACACGGTCCAGGTCCTCCACCAGCTGCTTGAAGGTGGGCCTCTGGGAGGGC
+
???DDDDDDDDDDD?D6BBC8=BE>C@88/7;A-;A6;?4>?@??'8=189===8?28<>>=+>A>:A<??88>AAAA>:2A>A3:>?#############
@8M4
CAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACACAGAAGAGTGACACCCGCCTCTGAGACCCTAGAA
+
@@CFADBDFHHHAEGHIIIIGGEBD?FEHGCEGIIIIGGII@BBCDCHGGGGGDHGHEEBDDEC8?DDC?AC?>B,:@C@CBDDDDDDDC@@>C?ACCCC>
@8M5
CAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACACAGAAGAGTGACACCCGCCTCTGAGACCCTAGAAGACCCTTGCAGGACAGAG
+
@CCFFFFDHHHHGGIJJJJJJJIIJGIHGJJJJIHHHIJGIIGIIJBGGHAEHFFFF@CEECEDBDDDDDDDDD@@BDDCDDDDBDDDDDDDDDDDBDDCD
@8M6
CGTGTCCTTACCGTGACGTCCACCGACACAGAAGAGGGACACCCGCCTCTGAGACCCTAGAAGACCCTTGCAGGACAGAGTCCCAGCACAAAGCGGAGACT
+
=;1A=BBDCBD?CEEBED<CF@EFEE?DDDDIIDEA(76BDCCD@ADA:A>ADDD@?A@AAAAAA><=A?AAA?89<?AA>AAA>:><???>A>?######
@8M7
CGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGTGTCACTCTTCTGTGTCGGTGGACGTCA
+
CCCFFFFFFFHHHIIEFGIIIIBHJIHGHIIJJIIJIGHFHIIIIJJJJJGEAEEHECHF?@ECECEEDDDDD############################
@8M8
CTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGTGTCACTCTTCTGTGTCGGTGGACGT
+
@@CFFFFFHHHDFIJJJIIJJIGEHIJIHIJIEGIFGHGJJHIJJJJIIIII=CHHHFFFFFFDCEEEEDDDDDB)99>>@::>@################
@8M9
CTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGTCACTCTTCTGTGTCGGGGG
+
CCCFFFFFHHHHHJHJIJJIJFIIJJJJJJJJIIIIJJJEHIIIIIJJGGDEHHHHBCFFFEEEEDACDDEDDDDDDDB######################
@8MA
GCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGTGTCACTCTTCTGTGTCGGTGGGCGTCACGGTAAGGA
+
C@@FFFDBHFHDFIAFBAEFHEGICGCFGIHCEHGHAFEGGFHDGGGEHCCCFGGEHIIIGHCC)0)4(:>>CC:@#########################
@8MB
CTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGTGTCACTCTTCTGTGTCGGGGGACGT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJHIJJJJJIJJJJIIJJJJJJJJHIAHHHHFFFFFFEEEEEEDDDDDD)904:::>>A################
@8MC
CCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACACAGAAGAGTGACACCCGCCTCTGAGACCCTAGAAGACCCTT
+
CCCFFFFFGHHHHJJIJJGIJEIJIIJIJJJJJJFHDHIJJIHHJGIEIHIIIJJJHHFFDEECDDDB;ACDDDDDDDDDDDDCDCDDDDCDDCDDDDDDC
@8MD
TGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACACAGAAGAGTGACACCCGCCTCTGAGACCCTAGAAGACCCTTGCAGGACAGAGTCCC
+
@@CDDFFFFHHHHIIJIJDHIGEEHIJJGHGEGIJJIIGIGHIIFIHHHFEHH?@CEFFDABBBDDDCCDDDBDDDDDDDDCDACCCCCD@BBCDCC::AC
@8ME
CTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGTCACTCTTCTGTGTCGGTGGGCGT
+
CCCFFFFFHHHHHJJGJGGIJJJJJJJIHIIJIIIAHHGJJIIIJJJIJJIJHHHHHFFFEFFEEEEEEDDDDDB##########################
@8MF
CGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGTGTCACTCTTCTGTGTCGGTGGACGTCACGGGAAGGGC
+
CC@FFDFFHHHHHJJJJJJJJJIHIJJIJJJJJIJJIJJIHGIIHJIJIIJHHJJJEIJJHFD######################################
@8MG
CAGAGGACCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACACAGAAGAGTGACACCCGCCTCTGAGACCCTAGAA
+
1?@;:=+=F8AFHGEFGGGHGIGIIFDH@CGEFHHIGAGHAFH@CHEFDFEBHIGDEHEFDEB?CB3=?BCC>?<,55>A>@B<B@B@AA<A:>?B9?CCC
@8MH
CCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACACAGAAGAGTGACACCCGCCTCTG
+
CCCFFFFFHHHHFHIJJIJJJJJJJJJIIJJJJIJJHJJGIJJJJJJJIIJHHHEFFFFEEEDCDDDDDDDDDDBBDDDDDDDDDB>@CCDABD@BDDDDC
@8MI
CAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACACAGAAGAGTGACACCCGCCTCTGAGACCCTAGAA
+
BC@DDFDFHHHHHJJJIHGJIGIJJ@GH@HHGIJIJIEGIJDHIJJGGGIIIHHGIHEHDEFEDDBDDDDCDCDD,>ACD>?BDBD>BDDDDDDBDDCCCC
@8MJ
GTAAGGGTCTGAGAGCCATCTGCTGGCACGGGGGGGCCCACACCCGCAGGGCAGCCCAGGGCTTCGCCCGGCAGACCCTGCAGGGGTGCTCCTCCGCAGGC
+
=11=ADDDFHF>DCF=FEEHGIC??C;+ACD<HG&65<B?@<BBBBB7:@B??7?BB8A@7?8<CB@;&59>9;?82??CB?C?<<058>@>>(9<99BB>
@8MK
GCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACACAGAAGAGTGACACCCGCCTCTGAG
+
@CCFFFFFHHGHFIJEIJGJJJGHGIIIJGIJGIFGGGHIGIIJJJJJJGGGEHHGHHFFFDDDDDDDDDDDDDDBDDDCCDDD4>@C@C@BDDDDBDDDD
@8ML
GGCGGGTGTCACTCTTCTGTGTCGGTGGACGTCACGGTAAGGACACGGTCCAGGTCCTCCACCAGCTGCTTGAAGGTGGGCCTCTGGGAGGGCGCGGCATG
+
CCCFFF@DDHDDHIGIIEGCG@DFH8?F?BFFH1;AH16;EFEDCFDC=?>CDD>>CCCC3AABDBCDDCCDBCDDCCDDBBBD@CDD<BBD9BBDDDB>B
@8MM
CGGGTCTTCTAGGGTCTCAGAGGCGGGTGTCACTCTTCTGTGTCGGTGGACGTCACGGTAAGGACACGGTCCAGGTCCTCCACCAGCTGCTTGAAGGTGNG
+
B@BFDDFFHHGHHJGGHIJJIIIFJJB4;A;=@=?C377=3;;?B>,59;;?;?BB?B8?@:CCBCB55(25(+9(:@CCCCCBD?B##############
@8MN
CCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGTGTCACTCTTCTGTGTCGGGGGACG
+
CCCFFFFFHHHHHJIJIJIJJJJIJJJJJGHIIIJJIJJJJJJJJJJJJGGIH(7?CFFCEDDEEDEDCDDDDDD5&004444>:C###############
@8MO
CCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACACAGAAGAGTGACACCCGCCTCTG
+
CCCFFFFFHGGHHJEFGGIHHJIHHII>FIIJJJJJIHE2CGCFHHIJIFG:AHFFFFFECCDDDBB(8?<?CADDD@BDBCDDCD>@@CDDBDDBDBDC>
@8MP
CGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACACAGAAGA
+
?@@F+ADDFHFHHJJIJIAEEHIIJJJJ@FBFHGJJ1@AFHHGCGGFHG@ECCEDCBC?BDDDDDDDD=?18CCCDDDBBBBDDBDD?CDDDDDB9<?CC>
@8MQ
TCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGTGTCACTCTTCTGTGTCGGTGGACGTC
+
@CCFFFFFHHHHGJJJEHIJJJJJIJIGHIJIIJBHHHIJJJIJIJIIJJHEEFHHHHFFFEDEEEEEEDDDD############################
@8MR
CGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGCCACAGAAGA
+
@@@FDDDFHFHHHJJIJJJGIDGIGI?HIHIIHEGHEHIJIJIEGHGGHF?BDFFDDDBDDDDDDDDD=A?BCCDDDD@8??@BDBDBDDD3<9BDDD>C>
@8MS
CTAGGGTCTCAGAGGCGGGTGTCACTCTTCTGTGTCGGTGGACGTCACGGTAAGGACACGGTCCAGGTCCTCCACCCGCTGCTTGCAGGTGGGGCTCTGGG
+
@@@DDDDDFFFFFEGIIIG7;'88@48CF9@@;4.)5=95?2>>'';?2=<955@>?<85;+27::9(+:>AB@BB#########################
@8MT
CATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGTGTGTCACTCTTCTGTGTCG
+
CCCFFFFFGHGHHIHJJJBGEHIBHBFHIIGG6AHI>GGHIIJIJJJIJIIGEHHF=EDE;ACCECCDDD>CCD@C:ABDD9@08(4>>:@>CCCA#####
@8MU
CTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACACAGAAGAGTGACACCCGCCTCTGAGACCCTAGAAGACCCTTGCAG
+
CCCFFFFFHHHHHJDHIIJJJJJJJJGIIEIIIJIIGEHEHJBGIIGJIGHIH/=BFFACEEEDACCDCDDBDDBBBDDDDCCDBDDDDDDDDCDDDDDDD
@8MV
CAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACACAGAAGAGTGACACCCGCCTCTGAGACCCTAGAAGACCCTTGCAGGAC
+
@@CFDFFFFHGCFIHIJJIJFIIIJDID=DGHGG>DGGGH?FBHGIGIJHIHHFFFFCEAE@CCCCC@DDDDDDDD:CCDDDCCDA(:?CC??>CCC>8?<
@8MW
CAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACACAGAAGAGTGACACCCGCCTCTGAGACCCTAGAA
+
CCCFFFFFHHHHHJJJJJJJJJJJJHIJJJJIJJJJJJJJJHJJJJJJJJIJJJJJHHHFFFFDDDDDDDDDDDD>@CDDDDDDDDDDDDDDDDDDDDDDD
@8MX
CCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACACAGAAGAGTGACACCCGCCTCTG
+
CCCFFFFFHHHHHJJJJIJJIJJJJJJJJJJJJJJJGHJIJJJJJIIJJJJHHHFFFFFEEEDDDDDDDDDDDDDDDDDDDDDDDD:ACDCDDDDDCDDDD
@8MY
CTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGTCACTCTTCTGTGTCGGTGG
+
CCCFFFFFHHHHHIFHIJJJJHGGIGHFIJJGHIIIIJJHJJJJJJJJIIEHGHHHBDFFFEEDEDCDDDECCDDDDDB######################
@8MZ
CTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGTGTCACTCTTCTGTGTGGGGGGGCGT
+
@@=DDDDAF<2C<EE@?1?E<FFGA@GF*99?FFB0/(88CFFEEFIE@ECC(...7>@DDD;A@CAC3;??=B@##########################
@8N0
CAGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGGCACTCTTCTTTGTCGGGGGGCGGCC
+
CCCFFFFFHHHHHIJGHGHIJJJJJIFDHJGIIDHIIIGGIJIIJGIJJJ@GHHHHHHGH@DEFEEEDDDDDD############################
@8N1
CCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACACAGAAGAGTGACACCCGCCTCTG
+
BCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJFHJGIJJIJJJJJJJHHHFFFFFEEEDDDDDDDDDDDDDDDDDDDDCCDD>ACDDDDDDDDDDDD
@8N2
CTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGTCACTCTTCTGTGTCGGGGGGCGG
+
CCCFFFFFHHHHHJJJJIIIJJJIJJJJHIJJJJJGJJJJJIJJJJJJJJJJHFHHGFFFFFBCCEEEEDDDDD###########################
@8N3
CCCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGTTACACTTCTTTGTTTGGGGGCGG
+
@@@DADFDHHDHDHEIFBFGHIGGGHGBBFFFHIGGGIGEDF@@FGHGGE@C===@CBCDD?EC@EDAA;?BBDD##########################
@8N4
CGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGGGACTCTTCTTTGTCGGGGGGCGGCG
+
CCCFFFFFHHHHHIJHIIIJJIJJJJIIJJJJJHHIJIJJJJJJIJJJIJDHHHGHHHHFFFFEEEDEDDDC@############################
@8N5
CGCAGACTTCGGGCTGGCCCGGGACGTGCACAACCTCGACTACTACACGAAGACAACCAACGGCCGGCTGCCCGTGCAGTGGATGCCGCCTGCGGCCTTGT
+
@<@DFDDDFHH?HIG)2<CFHHIGBGE?GEHI@FEGIIIHGFH>@CC),3=?BDCCAB?BB?;B#####################################
@8N6
CTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACGCGAGGGCTGGCCCTG
+
?=@=DDDDA?FFFHEHEDFD@D;DHEHGIGIHIG<FHIE@F@F@)7@EH?A;;77@CBC:'(,,:>ACCCB??B@?2<@B:A###################
@8N7
CTACCAGAAGTGCATCCACAGGGACCTGGCTGCCCGCACTGTGCTGGTGACCGAGGACAACGTGATGAAGATCGTAGACTTCTGCCTGGACCCGGCCGGGC
+
=?14ABBDFAFBFF:CCAF>+<CAFDEGGIC:?8?D??8@DBB=//))888/5/5=9?C?=<?######################################
@8N8
CCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACATCCACCGACACAGAAGAGTGACACCCGCCTCTGAGACCCTAGA
+
CCCFFFFFHHHHHJJJJJIJJJJJJJJJJIJJJJJIJJIJJIGIIJJJJIIIIGIJH)?EHFFFFDDDDDDDDDDD>CDDDDDDDBDDDDDDDDDDDDCCC
@8N9
CCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGTGGCACTCTT
+
CCCFFFFFHHHHHIJJJIJIJJJJJBG?EGHGBDFGGGBGIHIA@FHIGIFAEHFHHFFEFFFDECCDACCDCDDDDB?ACCDDDDDBDBB##########
@8NA
CCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACACAGAAGAGTGACACCCGCCTCTG
+
@@@DFFDF@FFHGEGGHGHIIIJIGIIJGDGIJEGI?FHDHICCGHIIICHE:C;BC@CEEEDABBDD@BB<CDDBDDB?@DC?A?(:@CCCDDBBD<B:>
@8NB
CCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACAAGAGTGACACCCGCCTCTGAGAC
+
CCCFFFFFGHHHHIIIIIEHDHIIIIGIIIIIIIIIGIIEHIGHIIIIIIIHEEBDFFFDEEDCDD@DBDDDDDD5>BBDCB@C@CDDD@BB@<BDCDDDD
@8NC
GGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACACAGAAGAG
+
@CCFD?DDDFHFHBHGGGEHIJIJEEHGHIEHGJIGGGIGIIJHGIIJEHFEEFB?=AACDDDDDDB?B<?C@CDCCB???@DB<B8ABB>@<@CDDDC##
@8ND
CGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGACTTCTAGGGTCTCA
+
@@CFFFFDFHH>DBGFGHHIIIEIIJHIIJJJJHIIHBGGIIIBFHIHHF<;@@AEDD@DDDDDDDDDDABBDDDDDDACDDCDDD(8<CCDCCCD9>CDD
@8NE
CGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCA
+
CCCFFFFFHHHHHIJGIIJJIIGJJIJJJJGIIGIJJIJIEIIFEHJHHFF?CCEEDDDDDDCCDCCDDDDDDDDDDDDDDCDDDD<CCDDDCDDDCDDDA
@8NF
GCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTACACCGACACAGAAGCGTGACAC
+
????DDB3C:<0@C@AE@E;?)18:))?B;??D=BBDIEDDI;@>DC7?65??;?>>AA39,9,<A>AAA>=<8<88((+8:A;?################
@8NG
CTCGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCT
+
@@@FFFFFHHDHHGIIGEGGHIAHHIJIJIIIIFIJJIIHIGHIIGCD>A??A;ACDDDDDDDD;?CCADD?BDDCCCCCCCCACD@B299ACCACCBCCD
@8NH
CGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACAAGTGTGA
+
?@;ADD=B4D:A:<A:AAFFIDG:FG;F9BF@F1C;FD4=C77=C===6).;B??=.5==?;=2(,<;8?(2>A>A:(5+2+22202?>?###########
@8NI
CTCGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCT
+
CCCFFFFFHHHHHIJJJHIJJJJJJJJJJJIJJJJJJIJIFIGHIGDCEEDDDACCCDDBDDDCCCCDCCBBDDDDCCCDDDDCDDBB?CDDDDDDCBCCA
@8NJ
CCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACAAGAGTGACACCCGCCTCTGAGAC
+
CCCFFFFFHHHHGJJJJJJJIJJJJIJJJIJJIIJJEHIGHJIJJGGIGIGHEHFFEFFEEEDCDDDDDDDDDDDDDDDDDB>CCCCDDDDBDBDDDDDDD
@8NK
CCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACAAGAGTGACACCCGCCTCTGAGAC
+
CCCFFFFFHHHHHJJIIIIJGIJJJJJFGGIIJJIJFFFHIIHGIIFIIJGHEHBEF@DCCEDDBDDDDDBDDBBDBBBBC8+:>ACDBDDDDDD@ACCCD
@8NL
GCCGGCATTCCTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGG
+
C@CFFFFFHHHHHJJJJJJJJJGGHIJIJJGHIGIJJJJJGIJIJIHHHHHHDFFDDDDDDDDDDDBDDDDDDDDDDDDDDCDDBDDDDDDDDDDDCDDDD
@8NM
GGAGCACAGACCCCACCGTGCCGGCATTCCTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTG
+
@@@FFFFFFHHGHIIJJJIIJJJIJJJJJJJJJJJJIJJJIA@@EEHBC?@@CE>B@DBCCCDECDDCDDD;B@?>B@?BB<B>9+>CDD9>5@?CC?C>A
@8NN
CGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACAAGAGTGA
+
CCCFFFBDHHHHDHIJIGIIIDHGGIJJIGIIIFIJIIJFIJIIGIGGHGEECFFCDDADDDDDBDDD?BBBCDDDDDD?B@DDBBDDCDDDDBDDCD4@:
@8NO
CGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACACAGAAGAGTGACACCCGCCTCTGA
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJIJJJJJIIJJIJIJJJJJJJJJHHHHFHFFFFFDDDDDDDDDDDDDDDDDDDDDDDD@CDDCDDDDDDDDDDC
@8NP
CGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACACAGAAGAGTGACACCCGCCTCTGA
+
CCCFFFFFHHHHHJJJIJJJJJJJJJJJJJJJJJJGIJIJJJJJJJJIJJHHHHGHFFFFFDDDDDDDDDDDDDDDDDDDDDDDD>CCCCDDDDDDDDDDD
@8NQ
CTGCGGGAGCACAGACCCCACCGTGCCGGCATTCCTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTG
+
@@@DDDDD:F;AF?FGBGHGBHHIIABGHIGGAHICHIGEAEECBEE;?<?@:;8>CAC7@;BBC>>ACA@ACC@@9>?<5()<@>>@<9?C::AB599?A
@8NR
CACTGCTGCGGGAGCACAGACCCCACCGTGCCGGCATTCCTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCG
+
@@@DDD?BFDH<CEHGHGHGIIBFHIG<?DDDEB'4-@EGHGCCEEDECC?B5;;/;872>::@BD7;BC:3:>AA:AC:A@D@B@?<?BBB99B234:A#
@8NS
CGCTGCTGCGGGAGCACAGACCCCACCGTGCCGGCATTCCTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCG
+
@<@FFFFFGGHHDGEHGBGCHGGIJJFHIIFGEBFHBHHHH>HEF?DDDCD;B7=?B=58ACCDBDB@@:A>>:>CCD@@:<@B?BB>ABBB@9@8?CC@9
@8NT
CCGCTGCTGCGGGAGCACAGACCCCACCGTGCCGGCATTCCTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCC
+
@=7BDFDDFHDDFEGEHIGCEFGDFHGGIIABGHIGEHE=EEE>B;BA;5;?B;??B;;58>@C:0;@7?CAAD>4>@@@AC>B??5<BA?>>@B98(:>@
@8NU
CTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGGCAGCAGTAACACCCGCC
+
==;DBBD++<<CC18):E;1??BE@DDD)8?BF*88)8=@;@@@7@@;.;-62@B2;2>6,,55,;5@>?###############################
@8NV
CTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACAAGAGTGACACCCGCC
+
CCCFFFFFGHHFHJIJJJJJJIIIIJJJJIJJJJJJIJJJJIJJGIIDHHFDBDFEEEEDDDBDDDDDDDDBBBBBDDD@AB9BBDDBCD@CCDCCDBBDD
@8NW
ATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACACAGA
+
==:DA6@<CADFD@FEBA?DEF6)066(8;C>3=6@(551AEDDDB@@A9>;>A@B?=(9?7?5?38?<39&8<8:@>@>A>??@################
@8NX
GGAGGCGAAGTGGCCACTGCTGCGGGAGCACAGACCCCACCGTGCCGGCATTCCTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCC
+
@@@BD?D<?@CD9ACB8?:?BGEHEH6DFCHGGEGIIE;B=<?BBCBB?;355>C@CCC@BBBBB@88@0&&)+3>AA99&5?>C>C@>AC:4:A09B8>B
@8NY
CTTAGGGATTGCACCAGGAGGCGAAGTGGCCACTGCTGCGGGAGCACAGACCCCACCGTGCCGGCATTCCTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGC
+
@@@DFFDFBFDHFIIJBBBDGIGHGDBFGHHIJIGHGGIIIBEEBBB?@CEDBDDDDDABBDDBDBDDCDDCCAC9-?<@B>B?><>@B@CDCDBD<>@CD
@8NZ
CGCAGGCTTCCTTAGGGATTGCACCAGGAGGCGAAGTGGCCACTGCTGCGGGAGCACAGACCCCACCGTGCCGGCATTCCTCCTCGGCTCCGTGCGGGGTT
+
=+:B:DDADD::DDB>;E:F<B>D;BEE:C@?D:D:BBECCAA@3=@@A<A>6/8???=A9==<<50&+25<>305;AA>AAA##################
@8O0
CGCAGGCTTCCTTAGGGATTGCACCAGGAGGCGAAGTGGCCACTGCTGCGGGAGCACAGACCCCACCGTGCCGGCATTCCTCCTCGGCTCCGTGCGGAGTC
+
@BCFFFFFHHHHHJJIJJJJJJJJJJJIJJJJIIJJBGHIJJJIJJIJJGHFDBDDDDDDDDDDDDDDBBDDDDDDDDDEDDDDDDDDDDD>ABDDDDD2>
@8O1
GGCAGACCCTGCAGGGGTGCTCCTCCGCAGGCTTCCTTAGGGATTGCACCAGGAGGCGAAGTGGCCACTGCTGCGGGAGCACAGACCCCACCGTGCCGGCA
+
CCCFFFFFHHHHHHFIJFGIIJJJJJJJIJIJIJJJJJJJJJIGIIJJJJHIHHHFFDDDDBDDDDDDDCCCDDDDDBDBDDDDA?BDDDDDD<ADDDD@<
@8O2
TGCCCACACCCGCAGGGCAGCCCAGGGCTTCGCCAGGCAGACCCTGCAGGGGTGCTCCTCCGCAGGCTTCCTTAGGGATTGCACCAGGAGGCGAAGTGGCC
+
CCCFFFFFGHHHHJJJJJIJJJJGIJJJIJIIJJGJJFIHCHIHGHHFFDFCA@DDDDDDDDDBBD>BDDDDDDCDDCCDDDCDDBDD?@BBD@BB8AD@@
@8O3
CCGGGACGTGCACAACCTCGACTACTACAAGAAGACAACCAACGGCCGGCTGCCCGTGAAGTGGATGGCGCCTGAGGTCTTGTTTGACCGAGTCTACACCT
+
@@@DDDDDHFDDFEGGF@GHBH;?D?FGFH<?F3?FEC8<@=CA>A'58699?=?8;?@##########################################
@8O4
CTGGCACGGGGGTGCCCACACCCGCAGGGCAGCCCAGGGCTTCGCCAGGCAGACCCTGCAGGGGTGCTCCTCCGCAGGCTTCCTTAGGGATTGCACCAGGA
+
?<?D?DDDHFHH::DBHIIIIIEHIIHFEEEEC==BBBB@9A5=@B?7?AAB<ABBCCBC>A7;8>?@CC>ACBB@<BB<CCCCCC@CBC?CCCCCCBBB<
@8O5
GGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACACAGAAGAG
+
@BCFFDDDHHHFGIJJIGDG>HGGHIIJIJIJGIJIJJJIJJGGFIJIHHHHHFEFDCACDCBDDDDBD<ADDDDCDD?BBBDBDDDDBB>@5<?BD>?CB
@8O6
CCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACACAGAAGAGCGACACCCGCCTCTG
+
=8+4=@@DDFDDFG@FAED;EE?DBFFEFEIIF3DG0BFEFIB;(8=C((.:4=@BBDBCCCC;?1=5538?:?###########################
@8O7
GGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACACAGAAGAGTGACACCCGCCTCTGAGACCCTAGAAGACC
+
@??DDDDDHDHHHGGGJJIIIEHDE=GFHGGGIHHIGDGGGFGGGJEGBDEFH;AHHBHEDCDDCBDCCCBA@@>>@@B<>B>@CDDDDDDDCCCDD@>?C
@8O8
GTCTGAGTGCCATCTGCTGGCACGGGGGTGCCCACACCCGCAGGGCAGCCCAGGGCTTCGCCAGGCAGACCCTGCAGGGGTGCTCCTCCGCAGGCTTCCTT
+
@@@FFFFDHHHHHJJJJJIGHIJJJIJJ<FEHIJJIHHHDFDDDDD@DDDDDDDDDDDDDDDDDDDDDBDDDDCBDAA>@55?CDDDDDDDDDDDDCDDDC
@8O9
GGGTCTGAGTGCCATCTGCTGGCACGGGGGTGCCCACACCCGCAGGGCAGCCCAGGGCTTCGCCAGGCAGACCCTGCAGGGGTGCTCCTCCGCAGGCTTCC
+
@@@DDDEDFHHHHIGGHAE:CGH+CGGHIIHG=DE<@C=;BDCC@:8(<=BB???B5<ABCBBCB;AA12<AA<(3<?><00)0?CCCCC?B>955>?A?C
@8OA
AGGTAAGGGTCTGAGTGCCATCTGCTGGCACGGGGGTGCCCACACCCGCAGGGCAGCCCAGGGCTTCGCCAGGCAGACCCTGCAGGGGTGCTCCTCCGCAG
+
BCCDFFFFHFFHHJJEHIIJIIJEJIGGIJJJIIIJIEHHHHFFFDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDC?>959?ACDDDDDDBB
@8OB
CACAGGTAAGGGTCTGAGTGCCATCTGCTGGCACGGGGGTGCCCACACCCGCAGGGCAGCCCAGGGCTTCGCCAGGCAGACCCTGCAGGGGTGCTCCTCCG
+
@@?DFFBDFHHHHIIFGHE@HIHIEHHIDHEHIGGGDHIGEEDFFFDCCBB9==:=@?<2<8A?D>BDBCDDBDDBAADDD<?<9ACCDD009BCC@CCA3
@8OC
CTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACACAGAAGAGTGACACCCGCCTCTGAGACCCT
+
@C@FFFDFHHAHHJHE@DHGGIGI@GCEHCGHEHIEHIIGGA@GF<B6@FCFDC<@;A1?BB/=BAC@@@88<5>CCCA+:(+:>?B@3>BDC>>A:@@AC
@8OD
CAGAGGTGTGTGCACAGGTAAGGGTCTGAGTGCCATCTGCTGGCACGGGGGTGCCCACACCCGCAGGGCAGCCCAGGGCTTCGCCAGGCAGACCCTGCAGG
+
CCCFFFDDHHHHHJJIIJHHIIJJJJJJIJGIJJIJJJJJJIIJJJJJJJHA>BDDDDDDDDDDDDDDDDDBDDDDDDBDDDDDDDBDBDDDDDBDDDCCD
@8OE
CCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACAAGAGTGACACCCGCCTCTGAGACCCTAGAAGACCCTTGCAG
+
CCCFFFFFHHHHHJJJJJHIJIIJIJJJJJJJJJFHGHIJJJJJJHIIJJJJEIJJHHFFDEED;CDDDDDDBDDDDDCCCCDDDDDDDCDD?CBCDDDCD
@8OF
CGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGCGGTCCACCGACGTGAGCCG
+
@@@FDDDBFHHAHGGG@GHBHHEGAGHJ)?8?DHBGGDACHGGGEH>;?AEEDEFBCC=AACD@(<CB8ABDCCCCDD9??####################
@8OG
GTTGGGGCTGTGCTCTCAGGAGCAGAGGTGTGTGCACAGGTAAGGGTCTGAGTGCCATCTGCTGGCACGGGGGTGCCCACACCCGCAGGGCAGCCCAGGGC
+
CCCFFFFFHGHHHJJIJJJJIIJJJGIJDHHGGHIJJJJJBGGHIIGHIJJIFHIIIJIIIJJHHEFHFFCADBDDDDDDDDDDDDDDD@@BDDDDABDDB
@8OH
CACCAGGTGGTTGGTTGGGGCTGTGCTCTCAGGAGCAGAGGTGTGTGCACAGGTAAGGGTCTGAGTGCCATCTGCTGGCACGGGGGTGCCCACACCCGCAG
+
CCCFFFFDHHHHDHGHGIGGHIIHHIJJJJGIIFGGGGHJICGHFGIJIJJGIHEEEFF?DFFFDECEACEDDCDCCCDDDB??5<5<BCC@@<BBBBDDB
@8OI
ATTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTAGTTTGCCCAGCCCTCCC
+
+:+?;A,++++<+?3A@>BCA<?+?AA=A):A:*05=55=7=6/:;;AAAA=A1/=@</635=???###################################
@8OJ
CCTGCCAGCCACCAGGTGGTTGGTTGGGGCTGTGCTCTCAGGAGCAGAGGTGTGTGCACAGGTAAGGGTCTGAGTGCCATCTGCTGGCACGGGGGTGCCCA
+
@@@=DDDDFFFAACD?2AAG@81:CFFFFFIF?B<898?FCC)-.6;7@E)6====A>DBDDA>BCA@5>;=AA;53((>?B:>@A@8945>BB#######
@8OK
CCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACACAGAAGAGTGACACCCGCCTCTGAGACCCTAGAAGACCCT
+
BC@FFFFFHHHHHJJJIJBGHGIIGGIJIIIIIIJ?FHIIJJJJJJGIIJGHIJJJGHGFDDAAC;CDD>CDCCC@BDBBDDCDADCD?ACC?:CDCDCAA
@8OL
TGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACACAGAAGAGTGACA
+
@C@FFFFFHHHHGIJJJJJJJIJJIIJDIIJJGHHGHIGIJGG>HGAHE(=?BFFDECEDDDDDDDDDDDDDB?<<BDDBDDDDDDDDD?BDDDC?:>A##
@8OM
CCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACACAGAAGAGTGACACCCGCCTCTGAGACCCTAGAAGACCCT
+
@@@DDADDHGHHHFDIEHI;GG;?CC=FGCAHEGBHGDFFHEHC;6-=C5;;85@ECEHFCCCCAA?>AACACCC@@BBBBBC>:>>@B@9?CCCCC99<?
@8ON
CATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACAAGAGTGACACCCGCCTCTG
+
@CCFDFDFHHHHHJJJJJJIJIIIIJFIIJJJEGGGIGEG@FGGIJHHHHFBDFFDCDBBDDDACCBD@?@DDBBDDDDBBDDAA?+44(+(8<5@@9<C:
@8OO
CGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACTCAGAAGA
+
CCCFDFDDHFHHGJJJJJGGHIJJGGIJHEHEGGGIIJJJGIIJJJFEFHCC;C?(=ACBBDDDDBCBBBAACCCACCD?A8<<?DB?@ABBD-<>>@>CA
@8OP
GACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCAACGTCACGCAGCTGGTGGAGGA
+
<@@DAABDF)C:?8EFEA?B>F;DDB<D)909BD@FEAAFFI>@@A4:;;@BBBCBACBB>@6=>8&8<?<(8??@0<8(+(2?80&8&05>@9+<?88<2
@8OQ
CAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACACAGAAGAGTGACACCCGCCTCTGAGACCCTAGAA
+
@@<DFFF?FDHFHEIEHBHIEHHGEBFH;FFDHGEGGGIGIFHAFGIIFCFGC;5CEHFFFDEBCDDBCDCCAAA>C>A@CDB59B@@@(4:>@BDDC?@@
@8OR
CATCAAATTCTAGTTTTACAGGTCCGCTCCTCGAGGAGCTGGCCATTTGGCCTGCAGCCACTTCTTCCTGAGGACTCAGGGTCATGGCCCTGCCAGCCACC
+
@CCFFFFFHGHHGHIIJIGIIIIIIIEIIGGIJJIHJGGGEHIJFGGIGGGIIGJIH@E>AEH=?D@DCDFECCCEDC@CA5:?CCD5(59?<A>ABB@D8
@8OS
GTCTCCTTGGTGGGGGTGCCCTTTTGCTGGTGGCGCCATCAGATACATCAAATTCTAGTTTTACAGGTCCGCTCCTCGAGGAGCTGGCCATTTGGCCTGCA
+
C@@FFFFFHGDHHIJI:DFGIGJJJIJJIIEGGFHIIGGHIHFHFHHHFDBDFFCEEC>CEECDCCCCDDDDDDDCDDDB<BDDBDCDDDDDEC3@C@8A<
@8OT
CCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACAAGAGTGACACCCGCCTCTGAGACCCTAGAAGAC
+
@@CDFFFFHHDFHJJJGHIJJJJIIJIJJIJIIGIHIIIIGHHGFHHHJIJG<CGHHAHDDBDEDDBDBD<A5>ACCC?<B@BDBCCCD@@BD<9A>CCC>
@8OU
CGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACACAGAAGA
+
@@@DDDBDBDHHAHGIBF8@FFHIGGHIII9FHIIG(5AGGCGGC@HCCCE@;@DBC??BBCC?9<AB@BBBCCCCCC<<BBBB09B0@A>BB@@C??C>3
@8OV
CTCACTGCTGCTTTCCTCAAGGGAGGCTTGAGGCCGGACCTCTCTCCCAGTCTCCTTGGTGGGGGTGCCCTTTTGCTGGTGGCGCCATCAGATACATCAAA
+
@@@DDFDFHGDDHGHIJJGCEHI+CFGIGIGEGEGEI8073BFEAEHIIGGEHIG3=C97?BCDB,5899>?CC:>::A<C@<95>@?C>C@C34>>@###
@8OW
CAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACACAGAAGAGTGACACCCGCCTCTGAGACCCTAGAA
+
@@@DDDD=FFHGFGGGHGGGIIIGHFFCBGIHII>BAAA9D0B==DDEDHAGECGHEHEDB>B>A:@=CB>>CD?:@CCCA<>-5@@@::>4:>BACC?>@
@8OX
CCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACACAGAAGAGTGACACCCGCCTCTGAGACCCTAGAAGACCCTT
+
CCCFFFFFHHHHHJJJJJHIJJJJJJJJIJIJJJFHFGHIIIJJJGIIIIIIIJJJHHFFDEECDDDDCDDDDDDDDDDDDDDDDDCDDDDDDCCDDDD@C
@8OY
CTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACTTCCACCGACACAGAAGAGTGACACC
+
@@@DDDDDF:?@D:@C?EFG?BFBDDBD@HIGGHBHIIGAF;7@7.5@6?HBD;;>A@;9;=55@@C>::?85<?(((::>?-00593+9ACC@C::>A##
@8OZ
GCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACAAGAGTGACACCCGCCTCTGAGACCCTAGACGACACTTGC
+
@@@DFFFFDHHFHGEFHGGGHI;@FH7;ECGGEFHFFHGIFEFEHA:FC(@(-;(5=?=8?B@2;?;;>>5:?2;@B59@:A>:>?B<<<>30<B######
@8P0
CCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACACAGAAGAGTGACACCCGCCTCTGAGACCCTAGA
+
CC@DFFFFHHHHHJJJGIIJJJIBHIEEGDGGGIIBEEGEIGHEGIJBGHFC<;CEEHEDB??A9A@BB?BC>CCD(:3:@C7<BB505@3>@CD?A9?CC
@8P1
CTGGGGGCTGGGCCTCACTGCAACCAGACTTGGTGTCACCTCCGAACGGGATGAAGTTTGGGTCATCCATTTTGTCCCAGTCGAGGTGGTAAGAGCCCCGA
+
<<@FFFFFFDAFDHGG@FEGEGGAGGGCGDGGG>D(/?BCEGHAGG;ABEDEBCEEEEED@?5<ADCC>ACDCCD@::>A>(58>B5?2&4:CAC?8?###
@8P2
GGGAGGGCTGCTTCGGCCAGGTGGTCATGGCGGAGGCCATCGGCATTGACAAGGACCGGGGCGCCAAGCCTGTCACCGTCGCCGTGAAGATGCTGAAAGAC
+
@@@DDDD<:?AD<EEBEGBHC:CGFGHIII9FH7FHAAEAHHEB6A@CCC@C?B;(9'87-5505;5<8?C@#############################
@8P3
GTCACCGTAGCCGTGAAGATGCTGAAAGACGATGCCACTGACAAGGACCTGTCGGACCTGGTGTCTGAGATGGAGATGATGAAGATGATCGGGAAACACAA
+
@@@?=ABAFB:A?CF@:C4<CEDD>C??FBDADDFCGFGF*?FI<BCFEEFFIII6BACD@77?@6((>>@A3?;5;AA;@AA:5(:>B@B<><B8AABBB
@8P4
TGAAGATGATCGGGAAACACAAAAACATCATCAACCTGCTGGGCGCCTGCACGCAGGGCGGGCCCCTGTACGTGCTGGTGGAGTACGCGGCCACGTGTAAC
+
@@@DDDADFFFAD@@8EEBB+AAEFEFA@<?C*?DFB?BF*?BEBEIE2C@EIFFBD<@:37;&578+>>4?9<?<+4+9?BB##################
@8P5
GGCGCCTGCACGCAGGGCGGGCCCCTGTACGTGCTGGTGGAGTACGCGGCCAAGGGTAACCTGCGGGAGTTTCTGCGGGCGCGGCGGCCCCCGGGGCTGGA
+
@;@DDADDFAFH?HGII1?@AEHBFBC>@>AACB1>A,<??B:>(898<@9@A02829>CCABBCCC@B8>A3@ACBBBB@B>BB90&55<B59@######
@8P6
CGCGGCCAAGGGTAACCTGCGGGAGTTTCTGCGGGCGCGGCGGCCCCCGGGCCTGGACTACTCCTTCGACACCTGCAAGCCACCCGAGGAGCAGCTCACCT
+
@@@D??DDAFFBDCGGHGHHHI<@GFGHCEHC0;A/>63''50)7585075&0<<?8<>99>:>@:48+89B?CC<<44+8(+<9<@5<58??AB?>A@8@
@8P7
CTGCAAGCCGCCCGAGGAGCAGCTCACCTTCAAGGACCTGGTGTCCTGTGCCTACCAGGTGGCCCGGGGCATGGAGTACTTGGCCTCCCAGAAGTGCATCC
+
CCCFFFFFFHHHHJIDFHI<;DBGGGGGICHEIFEGEFGHIGICEHHGC@D7?CHEBCB3;?BEDBB;?;BDD8A?AA3::>(34>ABB############
@8P8
CAAGCCGCCCGAGGAGCAGCTCACCTTCAAGGACCTGGTGTCCTGTGCCTACCAGGTGGCCCGGGGCATGGAGTACTTGGCCTCCCAGAAGTGCATCCACA
+
@CCFFDDFHHHHHJJJJIJJIIIJHIHIJFIGGGIJJIFHDEHIJIIJJIEHHHCEDDBFEDDB?=B>ABDCD@CCCDCDCCCABD9C8CC:@@@DCC:AC
@8P9
GTCCGCTCCTCGAGGAGCTGGCCATTTGGCCTGCAGCCACTTCTTCCTGAGGACTCAGGGTCATGGCCCTGCCAGCCACCAGGTGGTTGGTTGGGGCTGTG
+
@@CFFFFFGDHHFIIIJIJIJIJGI9FIIIJBHGIIGJFHGIEHIIIIH@CGDGGIIJHH?AD@DDDFDDEDDCDDDBDDDD@5>85?@9<??########
@8PA
CTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGTGTCACTCTTCTGTGTCGGGGGACGG
+
CCCFFFFFHHHGHJJJJHIIJJJJJJJJHIJJJJJGJIIJJJJJJIJJJJJICHHHHFFFFFDCEEEEDDDDDDD5<)4:>:@CD################
@8PB
CTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGTGTCTCTCTTCTGTGTCGGGGGACGT
+
CC@FFFFFHHFFDIJEI8EGIGIJJJJEIIEGDHH8DDHIGIGIIJJJIDDGEHGHEEFFEFDDCEEECCDBDDD##########################
@8PC
GAGCAGCTCACCTTCAAGGACCTGGTGTCCTGTGCCTAACAGGTGGCCCGGGGCATGGAGTACTTGGCCTCCCAGACGTGCATCCACAGGGACCTGGCTGC
+
>=<AAA>AC+<ABCCB<C=AAB>+2<<ABBABBBBBB<*0?AB7=1=)0;6A:4-=5;;>>@@96>@??;====?==7==;;:;;:??<9909<789;989
@8PD
TGCCACTTCTTCCTGAGGACTCAGGGTCATGGCCCTGCCAGCCACCAGGTGGGTGGTTGGGGCTGTGCTCTCAGGAGCAGAGGTGTGTGCACAGGTAAGGG
+
;1?DDFFFHFHBFGIEHBEHIDHIGI9AB>FG;3CF@;:?DF?GGG;@BD/;';A/;;?BDB<3>5;AA>@@CC>(<<<CCB(4<@?BB@:ACC@######
@8PE
CGGGATTGCACCAGGAGGCGAAGTGGCCACTGCTGCGGGAGCACAGACCCCACCGTGCCGGCATTCCTCCTCGGCTCCGTGCGGGGACTCCGCTTTTCCTT
+
??@FDDFDHFFHHIGGGEFGGHF:<<BDE=GII<B?F>68=E?>?CCFC?=;>?BABBB?@7@BCCDCC9ACC9@?<?#######################
@8PF
CCCGGGGCATGGAGTACTTGGCCTCCCAGAAGTGCATCCACAGGGACCTGGCTGCCCGCAATGTGCTGGTGACCGAGGACAACGTGATGAAGATCGCAGAC
+
CCCFFFFFGGHHDIHIJJIJIGIFJJJJIJ;F?FHIJJJJJJJII<GIJJHGIIEHHFFDDDDDDDDDDACDDABBDD-?918>AA@DDDACCDCDDDDBD
@8PG
GCACCAGGAGGCGAAGTGGCCACTGCTGCGGGAGCACAGACCCCACCGTGCCGGCATTCCTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTGCCTC
+
;??B?DB;CACCFHHG@9<D;BDFIGBGGIIDEAEE;;=>AA=BB<A<.;?=@=BBBC<BCCC?C8><?5?;(+09595?(:>C9<9>8ACD::AD#####
@8PH
CTAGGGATTGCACCAGGAGGCGAAGTGGCCACTGCTGCGGGAGCACAGACACCACCGTGCCGGCATTCCTCCTCGGCTCCGTGGGGAGTCTCCCCATTGGC
+
<@@DD??DBFBD+A>EFHH8388?@?@ADHGGIGB><B<<8/:/?DEC;A2>?AB?6<9@</8555:>CCC>CC###########################
@8PI
CAGAACTTCCTGGGCTCTGGGAAGAGCTTGAGCAGTCCAGGTCAGCCAGGGCACCTGGGCCAGAAGGCCCGCCCCACACCTCAGCACTCTGGGGGGCAGGA
+
@@@FFFFFFGDFFGHIJJFGIIJEHIEHIIGFHIJGHIJJGIGCHCHEHGIJIJJCFAHICDHHHFDFF?BCBDD5=BBDCBCDDCB>A>CCCBDBBBDD?
@8PJ
CCTGGCTGCCCGCAATGTGCTGGTGACCGAGGACAACGTGATGAAGATCGCAGACTTCGGGCTGGCCCGGGACGTGCACAACCTCGACTACTACAAGAAGA
+
@CCDDFFFHDHFDGIGGGHIHIJEGHIIJJJJGIJJIB=FGHIJJIIEDGEEHFFFF>BCDDDDBBBDDDDDDDDBDDDC<<@CCDBDD9A@CDDDCDDDA
@8PK
CCGCAATGTGCTGGTGACCGAGGACAACGTGATGAAGATCGCAGACTTCGGGCTGGCCCGGGACGTGCACAACCTCGACTACTACAAGAAGACAACCAACG
+
CCCFFFFFHHHHHJCHHJIJJJJEHGGIIFHGIIJJJGHCHIIJIJJJIIJGHFFFDEDDDD;?BBDBBCDDB?CCDDDDDDDDDDDCC<>CCDC??BDB?
@8PL
TGGTGACCGAGGACAACGTGATGAAGATCGCAGACTTCGGGCTGGCCCGGGACGTGCACAACCTCGACTACTACAAGAAGACAACCAACGGCCGGCTGCCC
+
;?@B;ADFDDAF1BEHHHED@DCHAFCEFGEIIIIIIICBE>FB<CHE<BC>>B;<?B@>???CC?77?;3>>>4>@C3?C>93<8<<<89-9505<>?A?
@8PM
GGTGACCGAGGACAACGTGATGAAGATCGCAGACTTCGGGCTGGCCCGGGACGTGCACAACCTCGACTACTACAAGAAGACAACCAACGGCCGGCTGCCCG
+
?@;?DDDD6F???AEG:FHGGCAGGGI>B):@DGFCBBG88@@6DEEEE?'39,5(,5>5((3+8@@BBCC:@ACC<?3?3(3<BB<B#############
@8PN
CGCACAGGTAAGGGTCTGAGTGCCATCTGCTGGCACGGGGGTGCCCACACCCGCAGGGCAGCCCAGGGCTTCGCCAGGCAGACCCTGCAGGGGTGTTCCTC
+
?;?=DDBDAFFDHI?FGIGIEHIIIIH<FFGGHII<DG:AB5?5??;??A;?B?@@?-2?@??<(+25<8@C#############################
@8PO
CGGTTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGGCACTCTTCTTTGTCGGTGGAGGTCC
+
@@@DDDFFDHHFHJJEGIIGJIJJII@FFHIJJFGIHGIJJIGIIIIGIBDDHHFHHFHG?@CC3>AACDBDD&0&09?9?:@>C################
@8PP
AAGATCGCAGACTTCGGGCTGGCCCGGGACGTGCACAACCTCGACTACTACAAGAAGACAACCAACGGCCGGCTGCCCGTGAAGTGGATGGCGCCTGAGGC
+
@C@FFDBDHGGHHJJJJJIIFHIJJHJJGGG@FEGGEGHEEHHFFFDEEEE>CCDCCCDDDDB<AB?BDDBBDB@DDDD<BB<@@@CCCA?##########
@8PQ
GCACGGGGGTGCCCACACCCGCAGGGCAGCCCAGGGCTTCGCCAGGCAGACCCTGCAGGGGTGCTCCTCCGCAGGCTTCCTTAGGGATTGCACCAGGAGGC
+
@CCFDDFDHHHFHJIBIGABBHE<HFHFBEFCACD6?BDDDBBB:AB?B@?AAACBD9A7<)5((+:99>9B>59&+93@3::+:?9(>3+4>AB??####
@8PR
CGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGTCGCTCTTCTGTCTTAGGAAAAGGAACATAGGTT
+
@@@DADFDFHDFHHIIIIIIIIADHD?F;F<DBFG@?BFGIGC=FHIEH97@FGH>G4C?#########################################
@8PS
CGCAGACTTCGGGCTGGCCCGGGACGTGCACAACCTCGACTACTACAAGAAGACAACCAACGGCCGGCTGCCCGTGAAGTGGATGGCGCCTGAGGCCTTGT
+
@;?=BDEBDHDHDGGIIIHI<CFD<D(?BFBD;;FEE54=A'=@77;@CC@>>;;C@BBB?1;8>;BBB-8BBC59?B@4@A(4:<95-0&8?9?<844:>
@8PT
TTCCTCCACGGCTTGCTCAGGGCTGCCAGACACTTTTCCTGGAGACACCATTTGGTTCTCAGAACTTCCTGGGCTCTGGGAAGAGCTTGAGCAGTCCAGGT
+
CCCFFFFFHHHHHJGGHIIEIJECGFFGE9@FHGHIJCHEEGEHIJIIIIFHI>DAEEHFEEHFDEFFFF>CCC@B?>CD=??ABCCCC9@@>?ACCA@C:
@8PU
CCGGGACGTGCACAACCTCGACTACTACAAGAAGACAACCAACGGCCGGCTGCCCGTGAAGTGGATGGCGCCTGAGGCCTTGTTTGACCGAGTCTACACTC
+
CCCFFFFFHHGHHJJIJJJJIGJJJJJJJJJJJGGGGIJIJJIJJJHFFDBDBDDDBDBBDCCDDDCBABBBBB?C<?BDDD:>C9:4><<529ACCC?>3
@8PV
CAGGAGCAGAGGTGTGTGCACAGGTAAGGGTCTGAGTGCCATCTGCTCGCACGGGGGTGCCCACACCCGCAGGGCAGCCCAGGGCTTCGCCAGGCAGACCC
+
B@@DFFFFFFAF3AACCEE<@HFGCHCEF>3?DEGC?BBFHG@>DFH*/?AFG<G<8'8@CCC@@D###################################
@8PW
TTCTGTCTAAGGAATAGGAACTAAGGTTTTCCTCCACGGCTTGCTCAGGGCTGCCAGACACTTTTCCTGGAGACACCATTTGGTTCTCAGAACTTCCTCGG
+
@@@ADDFFHHHHGJBHH@CFHGEHIIHGGGGGIJIGGHBBDGGGIIGGCGCHEI@=@>@GHDHHC3AB3?@66=A>5;;@C:>9AC:(;@>@CD@CA####
@8PX
GGGACGTGCACAACCTCGACTACTACAAGAAGACAACCAACGGCCGGCTGCCCGTGAAGTGGATGGCGCCTGAGGCCTTGTTTGACCGAGTCTACACTCAC
+
@@@AD@DDHFHHHIIJIGGHJGJIJJIGGIEBHFEGIIJJJIGIGG<>EBDEDD?@@@>5@C@@@?C-7@@DDCDDDDCCCCCDDDDB<B2?ACDDDCDCD
@8PY
GACGTGCACAACCTCGACTACTACAAGAAGACAACCAACCTGGTCCTTTGGGGTCCTGCTCTGGGAGATCTTCACGCTGGGGGGCTCCCCGTACCCCGGCA
+
@CCFFFFFGHFHHJJGJIIJJJJJJGIIJJJJIJJIJJJJIIICHIJJJJFB>AGGFGHEHCDBBB?C@CCDDED?D@BBD:<9@9ABDDD9>DDCD@5@<
@8PZ
CGACCCTGCAGGGGTGCTCCTCCGCAGGCTTCCTTAGGGATTGCACCAGGAGGCGAAGTGGCCACTGCTGCGGGAGCACAGACCCCACCGTGCCGGCATTC
+
BBBFFFFFHFHFDGFFHIJIJJJIJJGIHGIIIHIIIIJGGHGGHIJI?HEEEBDDDD@CD1<CDDCCDCDDBDBB<BBDCDDDDBDDD<8A<A>BDDDDD
@8Q0
CAACCTCGACTACTACAAGAAGACAACCAACGGCCGGCTGCCCGTGAAGTGGATGGCGCCTGAGGCCTTGTTTGACCGAGTCTACACTCACCAGAGTGACG
+
@@@DD8BDFHHHHGIGIIGFDF>9FDGHIDGIIIIIFEGGEGIHEEEEDBACCCCBC?B=BBCCBBB3:@CCCCCCA@-98<ACCCCA+9?<CABB+>C@<
@8Q1
CTCGACTACTACAAGAAGACAACCAACGGCCGGCTGCCCGTGAAGTGGATGGCGCCTGAGGCCTTGTTTGACCGAGTCTACACTCACCACAGTGACGTCTG
+
@@@7DDF?H?FHHGE>B3?EHEG=FGIIGIB>HGIGIIIFGHC?EEBCDDCBE/3;?ACCBDDDC>>>C>+4A;5@2A#######################
@8Q2
CAAGAAGACAACCAACGGCCGGCTGCCCGTGAAGTGGATGGCGCCTGAGGCCTTGTTTGACCGAGTCTACACTCACCAGAGTGACGTCTGGTCCTTTGGGG
+
C@@FFDEFHHHGHHIHGGIEHEHFGCEHH@@EFGFGH===D9BEDFB@CD15;>;>CA3:5@@8>@CCC>33:?3?BDD<A(4>CB<@C7A4:>>>CC?@>
@8Q3
CACCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGTTGCTC
+
@@@FDFFFFDHHFGGIE>HEIGGICHHEGCGGD>FHCDHEA><FEEEEHGHEEEDBD@C@CEA@E9>AB@;(<CCCCCC@:?9C>>::8?@##########
@8Q4
CAACCAACGGCCGGCTGCCCGTGAAGTGGATGGCGCCTGAGGCCTTGTTTGACCGAGTCTACACTCACCAGAGTGACGTCTGGTCCTTTGGGGTCCTGCTC
+
CC@FDFFFHAHFFJIIG?GGGHIGCF?FGBFEG;FFGG?)=A;?7?B3;;AACCBB8(9@AC>C@C9ABD(2844:@B@@<<?>ACACC:3<<95ACC@>>
@8Q5
CCGGGCAGCCCAGGGCTTCGCCAGGCAGACCCTGCAGGGGTGCTCCTCCGCAGGCTTCCTTAGGGATTGCACCAGGAGGCGAAGTGGCCACTGCTGCGGGA
+
@@CFFFFFHHDHHIJJJJIJIIJIJGHIJJJJJIJGIDIJ;BDGFHHGGFBCDB@BDDDCDCDA@CCC<CDDDDDDBDBB@>5>2:@?<ABCCCDACBBB0
@8Q6
CAACGGCCGGCTGCCCGTGAAGTGGATGGCGCCTGAGGCCTTGTTTGACCGAGTCTACACTCACCAGAGTGACGTCTGGTCCTTTGGGGTCCTGCTCTGGG
+
@CCFFFFFHHHGHJJJJJJIIJDGGGGGIEGBHEE7=D@EEHEEDFF@DFAB?5;@CDDCDDCCB@ADB4@@>B@B<?A:@A>CD>?@B-0<>@C:@3::<
@8Q7
CCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGGCGCTCTTTTGTGTTCTTGGGG
+
@?=AD?DDFDD8<AC<:::1?9::?6@@D*//?FFD===CF@F@7@=@==..?EDD>;?D;;;;65(;>;@##############################
@8Q8
CGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGTCACTCTTCTGTGTCGGGGGACGGCACGGTCAGGAC
+
@@CDDDDDHGDFDGGIF@HFHIGFEGCDEHHIEHIIHG;FBADHIFCFG?FHEHIJGEIIEE#######################################
@8Q9
CGGCCGGCTGCCCGTGAAGTGGATGGCGCCTGAGGCCTTGTTTGACCGAGTCTACACTCACCAGAGTGACGTCTGGTCCTTTGGGGTCCTGCTCTGGGAGA
+
C@@FFDDDDHHHHIJIJJJGHGJIJJJJIJIJJJDHIGIGHIIJIHGFBA=A@CECDDCDDDDBDDCCCCD8;?@D@CCCDDDDBB<<BDDDDDDDDCDD5
@8QA
CTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGGCTTCTAGGG
+
@@@DDDDDAFFFF::CFF?A8DGCGFBFEF@<FFIIIIIBFB64@;@DA2-=?>>:@?@BB'22=?>>BB@3>?88<+4>4+:4::(:@B<&0<?BA@:3?
@8QB
GGCTTCCTTAGGGATTGCACCAGGAGGCGAAGAGGCCAATGCTGCGGGAGCACAGACCCCACCGTGCCGGCATTCCTCCTCGGCTCCGTGCGGAGTCTCCG
+
1:?DDDD?HCBFHEG3CEBGIIJIIGIJF0@D)9?;FG(=FHDG3AAB</<?AC9>B92<B?B?<<@D75;;;CCACD9?C5<?BB@@88@@#########
@8QC
GCCCGTGAAGTGGATGGCGCCTGAGGCCTTGTTTGACCGAGTCTACACTCACCAGAGTGACGTCTGGTCCTTTGGGGTCCTGCTCTGGGAGATCTTCACGC
+
C@CFFDFFGHFHHIJJJGGGJJJBGDEHIJCAHIIGIJIBGFHIIHHJ@HGIIJHHH;>;CFBCEDEDDDCDDCCBB;?BDDDDDC>:??89ACDDDDDA@
@8QD
CGTGAAGTGGATGGCGCCTGAGGCCTTGTTTGACCGAGTCTACACTCACCAGAGTGACGTCTGGTCCTTTGGGGTCCTGCTCTGGGAGATCTTCACGCTGG
+
@??;DDFBFDDDHB>GHHEHIHIIIIIAFEHD>FHFF:DG<CGAA)=37@CGI9)=@EHHFF7?C@CCE@:?@?'8<((:(>C>A?A?-9>AA:>>?A>59
@8QE
GAAGTGGATGGCGCCTGAGGCCTTGTTTGACCGAGTCTACACTCACCAGAGTGACGTCTGGTCCTTTGGGGTCCTGCTCTGGGAGATCTTCACGCTGGGGG
+
@BCFDDDDHHHHFIIHGBHGIIEHHHGIEDHIDHICGHGI<FCHIIHFGAFEHEIJHHC?BBDEFEEACDB>BDDAC@A>CCCABBDCDDDCDBDBD7<5<
@8QF
GCCACTGCTGCGGGAGCACAGACCCCACCGTGCCGGCATTCCTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTC
+
@CCFFFFFHHHHGIBEFDHHGDGHHIBGHIFIHGBHGGHHFHHAEDFFDD=AB@BD@@?B;<CCDC57858@CCC@CCC>>ACD<?BDD@AD>39<<29@C
@8QG
AAGTGGATGGCGCCTGAGGCCTTGTTTGACCGAGTCTACACTCACCAGAGTGACGTCTGGTCCTTTGGGGTCCTGCTCTGGGAGATCTTCACGCTGGGGGG
+
@@CDFFFDFFHGFIJJJIIIJGJJGIJIIJIJGIIGIGHGHIIIIJIIJIGGACECHHHFCCEDFEDEDD;;ACCCDDCCCD?B<CCDDECDB?B3<<99<
@8QH
AGTGGATGGCGCCTGAGGCCTTGTTTGACCGAGTCTACACTCACCAGAGTGACGTCTGGTCCTTTGGGGTCCTGCTCTGGGAGATCTTCACGCTGGGGGGC
+
@@@D<DAD?D<@F??BBEEGCECFGI<@DHHEI;;??F@)?DBGH=;CG8=;@AEEEHHEEDD@?CC>;3;AC:@CCC:CC?@9>::@CCABB<9B<>9>5
@8QI
TCTAGGGTCTCAGAGGCGGGTGTCACTCTTCTGTCTAAGGAATAGGAACTAAGGTTTTCCTCCACGGCTTGCCCCCGNCCACCCCACACCTTTCCTCGANN
+
@@@DDDBDFHHHHEEGFEI@.'<=)=.=78=74.=@)=7=)=;@7)7?2((.6=;@ABAA:>A######################################
@8QJ
CTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGTGTCTCTCTTCTTTGTCGGTGGGCGC
+
@CCFFFDFHH:CFHGIJGICHH>GHHIG?DHEHBAHIEGD9B@FICG@EGA@6=CHFFFBCE3>>CDA>CBBB@B##########################
@8QK
TGGCGCCTGAGGCCTTGTTTGACCGAGTCTACACTCACCAGAGTGACGTCTGGTCCTTTGGGGTCCTGCTCTGGGAGATCTTCACGCTGGGGGGCTCCCCG
+
C@CFFFFFHHHHHGHIIIJJJJIIJDHDBGGGIJJIJIIJJBGFFGHHIJHIJJJJJHHHHFFFDDDCDDDDDC?BDBCCDCEDDDDDDBDDBDB>A@BDD
@8QL
TGGCGCCCGAGGCCTTGTTTGACCGAGCCTACACTCACCAGAGTGACGTCTGGTCCTTTGGGGTCCTGCTCTGGGAGATCTTCACGCTGGGGGGCTCCCCG
+
@@@FDFFAA?:CFEG@GDHDGGIHIJIGIEI9FGHI>GHJ=GH7=;=;;=CEB;;@CCEC3>B@BB:ACDC>:++8<5>:>3:>AB?##############
@8QM
CCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGTGTTACTCTTCTATGTCGGTGGACG
+
CCCFFFADHHGHHIIJIIFHGHIIGGJJJGIGIIJECGIGHBGGHGIIIGHEHA?EFFFDFFD>CEEEDACDDDDD#########################
@8QN
GCCTGAGGCCTTGTTTGACCGAGTCTACACTCACCAGAGTGACGTCTGGTCCTTTGGGGTCCTGCTCTGGGAGATCTTCACGCTGGGGGGCTCCCCGTACC
+
@@@DB>AB?FFHDIIGI<FFHDH?GGCE>FHE@FGIEDDHHG@FHBBDGHFG7FFHIII:46??CDBC6(;@?83-;@CCC?@B8??-<5&082<@B9@BB
@8QO
CCGCAGGCTTCCTTAGGGATTGCACCAGGAGGCGAAGTGGCCACTGCTGCGGGAGCACAGACCCCACCGTGCCGGCATTCCTCCTCGGCTCCGTGCGGAGT
+
@@BDFFFFHHGHHJFHIIIIIIJJGIIIJCFGGIIHG;FHIJCCCHEIIGEBDBDBBDDCDDDDDDB8@B?BB@<BBBDCCCCDDCBBBBBDDDD>BB9@2
@8QP
CCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGGGACTCTTCTGTGTTGGGGGGCGGC
+
@;?DDADDF?FFFF:FGIIGIEIIIIIBDAGFIIFBC;FFFIEFEIE;CEDEF>EEFBDDD.6>B;;6>?BBB############################
@8QQ
CTGAGGCCTTGTTTGACCGAGTCTACACTCACCAGAGTGACGTCTGGTCCTTTGGGGTCCTGCTCTGGGAGATCTTCACGCTGGGGGGCTCCCCGTACCCC
+
CCCFFFFFHHHHHJJEHIJEI;FGIJEIJIJJJJIJJDFGIJIGGIJJJJGHGGIIJGEEHHFFFFFE@ACBADDDEEDBDDBDDDDDDB<8?BBB9BBDB
@8QR
CGTGCCGGCATTCCTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAA
+
CC@FFFFFHHGGHJIJJJJJJJJJJJDHEHIGICDHGIAEIHHHGHHFFFCDFDAADBDDDDABBDD>B8>CDDDDDDDC@?CCCDB88<CA@CCC@@@?>
@8QS
CTGAGTGCCATCTGCTGGCACGGGGGTGCCCACACCCGCAGGGCAGCCCAGGGCTTCGCCAGGCAGACCCTGCAGGGGTGCTCCTCCGCAGGCTTCCTTAG
+
@@@DDDDFHHFFHHGHEG=E9FGFII?6;FH>EGG=/ABDDB8=@BDB<(5?<B@?C8BBB@B<ABBDDBDDDD??@@&08@ACCDD<BD39-<A?4+4>A
@8QT
CTGAGGCCTTGTTTGACCGAGTCTACACTCACCAGAGTGACGTCTGGTCCTTTGGGGTCCTGCTCTGGGAGATCTTCACGCTGGGGGGCTCCCCCTACACC
+
@@?BADADHDFFHGGE:CEFFF>BG<EHE3:BG>8)0?BFD1(?3;8=CCB;F)8'5-5=))7);37.;@A'(5;@CC@B@####################
@8QU
CTGAGGCCTTGTTTGACCGAGTCTACACTCACCAGAGTGACGTCTGGTCCTTTGGGGTCCTGCTCTGGGAGATCTTCACGCTGGGGGGCTCCCCGTACCCC
+
BCCFFFFFHHHHHJJGJJJJJHIJJJJJJJIJJJJJIFHIJIHIJJJIIJIJJIIJJHHHHHFFFFFFDDDDDDEDEEDDDDDDDDDDDDDDDDDDDDDDB
@8QV
GCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGTGTCACTCTTCTTTTTAAGGAATAGGAACTAAGGTTT
+
C@CFFFDDHHHHHJJJJHJJJJJJFHGJIIIJIFDIIIIIJ?DGHIIJJGIFDGHGIIGIIHDD#####################################
@8QW
CTCGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCT
+
CCCFFFDFHHHHHJJJJHIJJJIJJJJJJJHIJIJJJIJFII=FGGCDHHFFCCDCDDDB@BDCA<ACCDDABBDDDDDDDDDCCDDBB?CCCDDCCDA?<
@8QX
CGGCATTCCTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTC
+
@@<ADFFFGFFHHJJJI=FHBAEDGGFD8?*??DFGB74.=@4@@AHD4>'4?(5?';1=>:;'5>CCCBBD><CCCD@A>??A8AA:>>@##########
@8QY
CGCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGGCCCCCTTGTCGGTGGACGTCA
+
B@BFFFFFHHHHHIJJIFIIJGIIIJJIJIFGIIEIIGGGGGIIIJIJIGE=ADFDFFEEEEED>CDDEDCDDDDDB########################
@8QZ
CTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGTCACTCTTTTCGGTGGACGTG
+
@C@BDDDFHHGHGIFGIIBGIIIIHFGIIII@GHIGIICGGGIGEGGCGHIGGHG@DFFFECECDCD@CDCDD??;@########################
@8R0
CCCGAGTCTACACTCACCAGAGTGACGTCTGGTCCTTTGGGGTCCTGCTCTGGGAGATCTTCACGCTGGGGGGCTCCCCGTACCCCGGCATCCCTGTGGAG
+
;@@DDD?DHHHFDHEFGIIBFGHCDFEHEGII<DF?BFFEAG@@BFEGEI8CAA=CHHIGGICECHDDD?9>B9<BBBBB9@@?C?BBB00>A@CC@@?>B
@8R1
ACCGAGTCTACACTCACCAGAGTGACGTCTGGTCCTTTGGGGTCCTGCTCTGGGAGATCTTCACGCTGGGGGGCTCCCCGTACCCCGGCATCCCTGTGTGG
+
B@@DFFDDHHGDHIIIIJFG+3<EHGGHIIGIGGHIJ@DGHI<DGEHIJIIGGHEHGGIF>CHHFEDDFBD>595ABBD99B?BDDBBDB@CCB>CCC42?
@8R2
CCGAGTCTACACTCACCAGAGTGACGTCTGGTCCTTTGGGGTCCTGCTCTGGGAGATCTTCACGCTGGGGGGCTCCCCGTACCCCGGCATCCCTGTGGAGG
+
CCCFFDFFHHHHHJJJJIJJJHIJJIJIJJJEHIIJJJJJIGIGIIJJIIJJJJJHIJJJIIJHHHHFFDDDBDDDDDDDDDDDDDDD<BDCBDDDDC>BD
@8R3
CGAGTCTACACTCACCAGAGTGACGTCTGGTCCTTTGGGGTCCTGCTCTGGGAGATCTTCACGCTGGGGGGCTCCCCGTACCCCGGCATCCCTGTGGAGGA
+
CCCFFFFFHHHHHJJIJJIJGGJJJJJJJJHIIIJJIJIJIIJJJJJJJIIIIGHHIIIJIJJJHHFDDDDB@DDDDDDDDDDDBDDBDDDDDDDDDDDB#
@8R4
CGGGGGTGCCCACACCCGCAGGGCAGCCCAGGGCTTCGCCAGGCAGACCCTGCAGGGGTGCTCCTCCGCAGGCTTCCTTAGGGATTGCACCAGGAGGCGAA
+
CCCFFFDDFHHFHJIJJIJJJJIJIJIHHHHFFFEDEDBBDDDBDDDDDDDDDDCBDDB@BDDDDDDDD@BDBDDCC>CDCDD>?CC:@@CD?BBB@<9>3
@8R5
CAGGTAAGGGTCTGAGTGCCATCTGCTGGCACGGGGGTGCCCACACCCGCAGGGCAGCCCAGGGCTTCGCCAGGCAGACCCTGCAGGGGTGCTCCTCCGCA
+
?@@D?DDFAFDCFHEHEHGCGIHDH@BHGGEIIGGIIABEEHHFDF=CBDBBBDDB<B8?BBBB<ABCB>@BD?BB?B?BBDDBC?B>B&)8>>A939<9<
@8R6
CTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGTCAATC
+
@@@DD?@DHBAHHIG>FA<EHHGHIII<:CF@A<FDHGCHB<FGIGDGCEAEEEHBDB@CDCCCCC@C?@,;?CCCCACB>?CCEC>@?@9@#########
@8R7
CGAGTCTACACTCACCAGAGTGACGTCTGGTCCTTTGGGGTCCTGCTCTGGGAGATCTTCACGCTGGGGGGCTCCCCGTACCCCGGCATCCCTGTGGAGGA
+
@@@FDFFFHHGHGJIJJJIIBHHHIHI@GICGGGIIIJJJFHEIHGGIGGHIIIIJJIJIIJFIHE>DEDDDDDDDDDBDD?CBBDDDBDDDCC@CCC@D#
@8R8
CGAGTCTACACTCACCAGAGTGACGTCTGGTCCTTTGGGGTCCTGCTCTGGGAGATCTTCACGCTGGGGGGCTCCCCGTACCCCGGCATCCCTGTGGAGGG
+
?@@F?DDAFFBFAGIIIIGGAF>@FGHGIJBFDGEHIIJBDGIEID@HIGFEGGEDF@DHGCH@=ADEF?BB0?BB>B<>B04?#################
@8R9
CGAGTCTACACTCACCAGAGTGACGTCTGGTCCTTTGGGGTCCTGCTCTGGGAGATCTTCACGCTGGGGGGCTCCCCGTACCCCGGCATCCCTCTGGAGGA
+
;;=;DDD;DD8D:C@BEC:C+3C<8A@;C9E<BDADF;?D8??98?BBCBCC@C8@C>CCAD#######################################
@8RA
CGAGTCTACACTCACCAGAGTGACGTCTGGTCCTTTGGGGTCCTGCTCTGGGAGATCTTCACGCTGGGGGGCTCCCCGTACCCCGGCATCCCTGTGGAGGC
+
???BADDDDHFDBGIBD@GG<AEHB8C9?E?@F?C?DFHGHBFCDDGGII@DFH8;@>EACEH>:=',,39>5<??B509B@CB-9B399?B>:AC?@?##
@8RB
AAGGAATAGGAACTAAGGTTTTCCTCCACGGCTTGCTCAGGGCTGCCAGACACTTTTCCTGGAGACACCATTTGGTTCTCAGAACTTCCTGGGCTCTGGGA
+
CCCFFFFFHHHHHJJJJJIIIJHJJJJIJJIJJJGGIIIJIJIIFHC@CBAFGHHIJAGGGEHHDFFFFCEDEAEBDCD@DDCCDDDCDDDCBBDBDDAC<
@8RC
TTTGTATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGGCACCTCTCTGT
+
@?@ADBDDFHGGDHGHIGHIJGFBFII<G6?99BFFHJJGFGEFGBGC.==CCC?EACEBBC5=>AACC>CCDDCCAC@@CCDDBB@##############
@8RD
TTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGTCACTCTTCTGT
+
CCCFFFFFHHHHHJJJJJIJJJGIIJJFIBGIJJIJJJJGFHGGIGJIIIIJJGHHHHHFFFFDBEECDDDDDDCDDDEDDDDDDDB&9&&+4>ACC####
@8RE
TCTACACTCACCAGAGTGACGTCTGGTCCTTTGGGGTCCTGCTCTGGGAGATCTTCACGCTGGGGGGCTCCACGTACCCCGGCATACCTGTGGAGGAGCTC
+
CCCFFFFDBHD<<<CF@F@FHGIBAGCFEHGGGF@DDHFCG<FGIIIIIIBC@=FHGDHHBBEB435&08?:<@###########################
@8RF
CTACACTCACCAGAGTGACGTCTGGTCCTTTGGGGTCCTGCTCTGGGAGATCTTCACGCTGGGGGGCTCCCCGTACCCCGGCATCCCTGTGGAGGAGCTCT
+
CCCFFFFFHHHHHJJHIJJJIJIJJHIJGIJIIJJFIJIIHJJJIJJGIIHIJJJJJJJJJHHFDDDDDDDD;;>BDDDBDD<>CDDCC>CC@BB8?1<CC
@8RG
CTCAGAACTTCCTGGGCTCTGGGAAGAGCTTGAGCAGTCCAGGTCAGCCAGGGCACCTGGGCCAGAAGGCCCGCCCCACACCTCAGCACTCTGGGGGGGCA
+
CCCFFFDFHHFHBA9@FGH>FHEGECGGGIJGGIJ>FF>EHG@DFHGEGGECBGIGGI@C?CGHFEA3?=B?</9??BB@DBDBCCD>BCDC>39>BB@B>
@8RH
CCAGAGTGACGTCTGGTCCTTTGGGGTCCTGCTCTGGGAGATCTTCACGCTGGGGGGCTCCCCGTACCCCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGC
+
CCCFFF?DFFHDFEHIBGHHIIGIII?GFGHHIEFFIGBF@FHEIHEEHGEHIBHHD8BD??@@5>?<C?>BDD>ACBDC@C?CBD<?A8@@@AA>@CCDD
@8RI
CTTTCCTCAAGGGAGGCTTGAGGCCGGACCTCTCTCCCAGTCTCCTTGGTGGGGGTGCCCTTTTGCTGGTGGCGCCATCAGATACATCAAATTCTAGTTTT
+
@CCFFDDFDAHHFGHGGIIBCFH=FEHIGH9?8??DBGBA<FAFHCH@G7;@6?B9?BDC@C>ACCCC@??BA@>@>@C(:(4@ACCC@@C:@ACACACDC
@8RJ
CCAGAGTGACGTCTGGTCCTTTGGGGTCCTGCTCTGGGAGATCTTCACGCTGGGGGGCTCCCCGTACCCCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGC
+
@BCFFF?DDHHFHIGIJIGIJJJIJJCGECBFGGGIEGHGG@DHEIICHIBBH<HFDDDDDDDDDDDDDBDBB@<C?ACD>AA><?8<?8ACDDE:>>>A?
@8RK
GCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGCGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTATCGGCTCAGAGGCGGGG
+
??<?40AD8DD@6<:<:<2CF4?94??E)?:8@AA))97;'5,7?)7/'9;>AA=A5(:8(9<A>>A##################################
@8RL
CTTGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGTGTCACTCTTCTGTGTCGGTCGACGG
+
@@@FFFFFHABFHFGHIDGGHJJFIJFGFHGGGJJIJJJIJCHIJJIIBHEGCCEHGEEC@?;BEECE@CDD@BB##########################
@8RM
TGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGTCACTCTTCTGTGTCGGTGGACGTCACGGTAAGGAAACGGTCCAGGTCCTCCACC
+
@@@FFFFDHFFHHHIIIJJIJHHHIJJEHIJGHIIGIJJGGIIE/5)0039>39@>(3(3:55&(0(4509?<9>8AB#######################
@8RN
CGAGGAGCTGGCCATTTGGCCTGCAGCCACTTCTTCCTGAGGACTCAGGGTCATGGCCCTGCCAGCCACCAGGTGGTTGGTTGGGGCTGTGCTCTCAGGAG
+
B@@A?ADDHHHFFIIIJIIDDHIGHGGIIJIJJIJFEGIHIDIIIJIIGH)=CHHI;FE?GGCDHFEHFFB?;;;A@@DB@B@=BBDDBAD<>CCDDC?A@
@8RO
CGTCTGGTCCTTTGGGGTCCTGCTCTGGGAGATCTTCACGCTGGGGGGCTCCCCGTACCCCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGG
+
CCBFFFFFHHHHHJJJJIJJIJJJJJJJJJJIJJJJJJJJJIJJJJJDDDBDDDDDDDDDDDDDDDDDDDDDDDDDDBDDDDDDDEDDDDDDDDDDDDDDD
@8RP
CTCAAGGGAGGCTTGAGGCCGGACCTCTCTCCCAGTCTCCTTGGTGGGGGTGCCCTTTTGCTGGTGGCGCCATCAGATCCATCCAATTCTAGTTTTATAGG
+
@@CFFFDFBHHFDIIIJIHIIJGGIGEE>G<FEGH<DGHI4BD@4@CGFE',;??CC@@>:@CC(9<2&)55<34>(:(:@>A1@C###############
@8RQ
GCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGG
+
@CCFFFFFHHHHGJJIGIJFIHHIJJIJIIIIIJIHGIIJBHHGIIIGF<BBDDFFFEEDDDDDDDDDDDDDDDCB@<CCDDDDDCD??CDEDDDDDDDB#
@8RR
GGTCTGAGTGCAATCTGCTGGCACGGGGGTGCCCCCACCCGCAGGGCAGCCCAGGGCTTCGCCAGGCAGACCCTGCAGGGGTGCTCCTCCGCAGGCTTCCT
+
@@@DDDA>CFF2<:CBAEF:+3<C<)@CD-;;FE;;'=DDDC8/3=8588<?B??B@08?B<BB>??@(+<@B?BBB########################
@8RS
CTGGTCCTTTGGGGTCCTCCTCTGGGAGATCTTCACGCTGGGGGGCTCCCCGTACCCCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCA
+
B<@FDDDDDDHHA:CGEGJIGHFFH@;BGGHIHEEGGI>HHII8@9@BBD@D59BBCBDD;<BDDBA>@CC:AB@DDDDDCA@CCCCCCCA>CC9A#####
@8RT
CTGGTCCTTTGGGGTCCTGCTCTGGGAGATCTTCACGCTGGGGGGCTCCCCGTACCCCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCC
+
CCCFFFFFGHHGGJEHEHHIIIG9EGCGCEGGIJFHIIJJDIII1<BD?@<DDDDDDD@BDDDDCDCC@C?CDD@BDDDDDDEDCDDDCDCDDCCDBDD@8
@8RU
GAGGACTCAGGGTCATGGCCCTGCCAGCCACCAGGTGGTTGGTTGGGGCTGTGCTCTCAGGAGCAGAGGTGTGTGCACAGGTAAGGGTCTGAGTGCCATCT
+
???BDDDDDD<3<?BEE+3ACFFDIEIDI;ED;DDDED@@DIBBDA?8;AADDDDDCCDA.??@@>A>?;;(,(,:AAA??####################
@8RV
CCCGCTCCTCGAGGAGCTGGCCATTTGGCCTGCAGCCACTTCTTCCTGAGGACTCAGGGTCATGGCCCTGCCAGCCACCAGGTGGTTGGTTGGGGCTGTGC
+
CCCFFFFFHHHHHJGGIIJJIJJJJIJJJJIJIJJIIIJIJIJIJJJJIBFFGGIJIJHAEHHFFFFFDECCCDDDBCABDDACD2?BD8<BBDDB<B###
@8RW
CTCCTCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGTGTCACTCTTCTGTGTCGGTGGGCGTCACGGTAAGGACACGGTC
+
C@CFFFFFDFFBHHJIGIIJJJIIIIEGGIJIII?DHIJJIJJIFGIIJGGIGHGGB3;8(,5>ACDC#################################
@8RX
GGTCCTTTGGGGTCCTGCTCTGGGAGATCTTCACGCTGGGGGGCTCCCCGTACCCCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCAC
+
BC@FFFFFHHHHGJIJJJJJJJJJJJJJJJJJJIJJJJJJIIDDDDDDDBDDDDDDDDDBDDDDDDCDDDDD@BDDDDDDECDCCDDDDDCDC?BDDDDDD
@8RY
GGTCCTTTGGGGTCCTGCTCTGGGAGATCTTCACGCTGGGGGGCTCCCCGTACCCCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCAC
+
@@@FDFFFD?HGFHIIIIIJIEIIII>GGIEHIIJJEEBEGB&6<DDDDBBBB<ABBDBDDDDDCD@CCA@BDBDDCDDDD>CCDCCCAC::??859>@@<
@8RZ
GTCCTTTGGGGTCCTGCTCTGGGAGATCTTCACGCTGGGGGGCTCCCCGTACCCCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACC
+
B@@FFFFFGHHDHGGGIIIJIJJFIEGIJJJJJIIGJJJJDBDBDDDDB57?BDBDDD;BDDDDACDCCDD<?BBCDCCEDDDDDDAC>>A?A?>B7?B?8
@8S0
CACACCCGCAGGGCAGCCCAGGGCTTCGCCAGGCAGACCCTGCAGGGGTGCTCCTCCGCAGGCTTCCTTAGGGATTGCACCAGGAGGCGAAGTGGCCACTG
+
B?@FDDDD8FD>AHGIIJJIIIIJJJIHIJIJJJJIIIIIJ@DE=;5@=<=@CA3?C@B??BBD9?CCACACDDDDCCCCCD18A?>8>B>B8>@B8>0:@
@8S1
GTCCTTTGGGGTCCTGCTCTGGGAGATCTTCACGCTGGGGGGCTCCCCGTACCCCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACC
+
CCCFFFFFHHHHHJJJJIJIIJIJJJJJJJIJJJJJJIJJJDDDDDDDDB@DDDDDDDDDDDDDDDDDDDDDDDDDDDDEDDDCDDDDDDDDDDDBDDDD@
@8S2
CTTTGGGGTCCTGCTCTGGGAGATCTTCACGCTGGGGGGCTCCCCGTACCCCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCA
+
C@@FFFFFHHHGHIIJJJIJJJIJJJIJJJIGGIJJJJDCDDDDDB:@BBCBD<BDDDDDDD@CDCDDBDDDDDDDEC>@>CA@CC@C<8AB70?######
@8S3
CTTTGGGGTCCTGCTCTGGGAGATCTTCACGCTGGGGGGCTCCCCGTACCCCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCA
+
CCCFDFFFFHHHHJJJJJIJIJJJJJJJJJJJJIIJJJDDDDDDD@BDDDDABDDDBDDDDDDDDDDD?BDDDDDDECCDC>CDCDDDDDDDDD@BDDDDB
@8S4
GGTTGGGGCTGTGCTCTCAGGAGCAGAGGTGTGTGCACAGGTAAGGGTCTGAGTGCCATCTGCTGGCACGGGGGTGCCCACACCCGCAGGGCAGCCCAGGG
+
B@BDDFFFHGHHHJJIJJIJJCGIIJHIJ?GBDFGIIIJIJBGDHIIBGICGICHGIJJJJFG>AEEFFFDD@D-9<CDC?8?BB9<09@DDBDDBD<??5
@8S5
CAGGAGCAGAGGTGTGTGCACAGGTAAGGGTCTGAGTGCCATCTGCTGGCACGGGGGTGCCCACACCCGCAGGGCAGCCCAGGGCTTCGCCAGGCAGACCC
+
@@CDD7DDHHGH<ECHGBHDHGII9CHGGHAGG9DFHGIGEHGEH4B9B=BDGGGGB33<5:@B88?BCBBB>BBBB7??BBC<<<230)5?5?@8??A?A
@8S6
CTTTGGGGTCCTGCTCTGGGAGATCTTCACGCTGGGGGGCTCCCCGTACCCCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGACACCGCA
+
@@@DDD1DFFFFFEIIII+32+<?EFAG9CD@@FFIG<3B3?8?BB@BB8A@BBBB&99?BB@B?BB7<B?8@BABBA@B@ABB3:AAB?@##########
@8S7
CTTTGGGGTCCTGCTCTGGGAGATCTTCACGCTGGGGGGCTCCCCGTACCCCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCA
+
@C@FFFDF1DCFFBGHEFCF>GBGH@GIGG8DGD:1?FD@&2(+5707?03<55759>>BCCDCDD???@BADAACECD@:>>@:4>:A<8&5<@?<A@>5
@8S8
AAGGAGCAGAGGTGTGTGCACAGGTAAGGGTCTGAGTGCCATCTGCTGGCACGGGGGTGCCCACACCCGCAGGGCAGCCCAGGGCTTCGCCAGGCAGACCC
+
+:=BDDDD??FF?=FDHAEHIGGIAEHFGGGCEG<4DDEGIIGCHGGAG=EG>GAH:BDD<ACBDBB@@>99;B@?5?B@@@<00??AB>5<9?#######
@8S9
CTTTGGGGTCCTGCTCTGGGAGATCTTCACGCTGGGGGGCTCCCCGTACCCCGGCATCCCTGTGGAGGAGCTCTTCCAGCTGCTGAAGGAGGGCCACCGCA
+
@CCFDAADFHHHGI>FHGGIJJGGHIEIAEABFEGIIE5@9BBDBBB@DDAB5BDBBC>ACDDD<><@?<1?CDCC3:4?>C>CCA@@A?###########
@8SA
TTGGGGTCCTGCTCTGGGAGATCTTCACGCTGGGGGGCTCCCCGTACCCCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATG
+
CCCFFFFFHHGHGJIJJJJIIJJIJJIJIJJJIJJIDDDDDDDDBDDDDDDDDDDDDDDDCDDDDDBDDDDDCDEDDDDDDBDDDDCBD9@<@DBDDDBBD
@8SB
CTGAGTGCCATCTGCTGGCACGGGGGTGCCCACACCCGCAGGGCAGCCCAGGGCTTCGCCAGGCAGACCCTGCAGGGGTGCTCCTCCGCAGGCTTCCTTAG
+
@@@B?+=DDHFDDEHC>3AB:FFHII7@DFI;;CHEHHFDDD@?7?<<@?BDDDDBC5B7?;((28<A?AC?B?C<5909@CCCC?CDD9@05<CCC>>AC
@8SC
GTCCTGCTCTGGGAGATCTTCACGCTGGGGGGCTCCCCGTACCCCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAA
+
CBCFFFFFHHHHHJIIJJJJJJJJJJJJJJJDDDDDDDDBDDDDDDDD@DCDBDDCDDDDDBBDDDDDDECDDCDDDDDDDDBD@@9?BDDDDDBDDDCC@
@8SD
CTCTGGGAGATCTTCACGCTGGGGGGCTCCCCGTACCCCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGC
+
@@@DDDEFHFDDFIIJJGIJJBGFI6@<BBDD@8BDDDDBBDDBDDDCCACCDD@BDB@@AACD>CACDDCDCDDC??9>B<2<?9>B<@BDC4<BBB?##
@8SE
CTGGGAGATCTTCACGCTGGGGGGCTCCCCGTACCCCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCA
+
@?@BBDD@?DFFHIIGHIEECEHBBDB@DDDD6?BCADDBB@CDBDDACCCBD??B?ACD>CCCDDCDCCCDDABDDD@BDD?>@BBDDD@CDABD@<@BD
@8SF
CTGGGAGATCTTCACGCTGGGGGGCTCCCCGTACCCCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCA
+
BCCFFFFFHHHHHJJJJJJJJJJDDDDDDDDBDDDDDDDDBDDDDDDDDDDDDBBDDDDDDECDDCDDDDDDDDDDDDDDDDDDBB>BDDCDBDA@BDBD<
@8SG
TCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGTCACT
+
@CCFFFFFHHHHHJIJJJIJJJIIJAGHGFHGIJGJHGGIHIIJJGIGIHFFEEBEFFFEEEECECDDDDD?CCCCDD@CD?CDDDDD><BDDB#######
@8SH
CGGGGTGTCACTCTTCTGTCTAAGGAATAGGAACTAAGGTTTTCCTCCACGGCTTGCTCAGGGCTGCCAGACACTTTTCCTGGAGACACCATTTGGTTCTC
+
???DB0<0AACDABEEEEDEEFEDFIIEEIEDBD?DE>?DDDCDEEADDD6@A/;A;@@=?CDD9=76(6>???>;>A>AA>A##################
@8SI
CTTAGGGATTGCACCAGGAGGCGAAGTGGCCACTGCTGCGGGAGCACAGACCCCACCGTGCCGGCATTCCTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGC
+
CCCFFFFFGHGHGJJJJJJJJJJIJJGGGHIGIJIIGIJJIIFFFFFFEEEDDDDDDDDBDDDDBDDDDDDDDDDD@BDDB-889>B902>CDD@BB<BC#
@8SJ
GGGAGATCTTCACGCTGGGGGGCTCCCCGTACCCCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAAC
+
@@@FDDEFHFHGDHIGIIIE?9B6ABBDDBBBBCBDDDDBDCBDD@CD@<<?22<ACCDDCCDDDDDDC@CCDDBB0<<?<>@DBBDC>>AB??A9BDDDB
@8SK
AGGGATTGCACCAGGAGGCGAAGTGGCCACTGCTGCGGGAGCACAGACCCCACCGTGCCGGCATTCCTCCTCGGCTCCGTGCGGAGGCTCCGCTTTGCATT
+
?@@FFFFFFBHDFDIGAGHIIGIAD<FGHGIIF@B@GH@54=9CDFDDCDCDDD'59=9?=BB@ACED3>CCB;?BBB>B?<<BBD&8<?###########
@8SL
GGAGATCTTCACGCTGGGGGGCTCCCCGTACCCCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACT
+
CCCFFFFFGFDHHIIGJEGIDDDDDDDDBBBDDB@BBBDCDDDDDDDDDDDDD?CCDDEDCCDDDDCD:@CD?5<<?BBDDDD<8<:@C<BDDB>5<BBD>
@8SM
GGAGATCTTCACGCTGGGGGGCTCCCCGTACCCCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACT
+
@@?DDDDDDHF<BB<GB1CEB33???BB5B??ABBBBBBC>A@C88?3<?8<A<:ACCCCC@:A9>::>A??<@-&+80+0559B?A3>AAA<8<BBB@?9
@8SN
CCTGGAGACACCATTTGGTTCTCAGAACTTCCTGGGCTCTGGGAAGAGCTTGAGCAGTCCAGGTCAGCCAGGGCACCTGGGCCAGAAGGCCCGCCCCACAC
+
CCCFFFFFGFHGHJJIJIHIJJJJJJJIJJJJIJJIJJIDHJJIIIIJJIGGIJJJCGIIJIJJJJIJHHGDFFFDDEECDDDB@DDDABDBD<BDDBDDD
@8SO
GAGATCTTCACGCTGGGGGGCTCCCCGTACCCCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTG
+
@@@BDFFFGHHHHGIJHID6:BBDDDDBBDDDDDDBBBDDDCD@A3>AB<<AACDCD:>AC@@C@ACCCC<ABDDBBD<BD9<?8>AC?AADDDBD9<@D3
@8SP
GAGATCTTCACGCTGGGGGGCTCCCCGTACCCCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTG
+
@CCDFFFFHHHHHGIJIHGBD6BDDDBBDDDDDD@D17CDDCC3@CCBB??B?CCCDDC>C>@C@AC@ACBD9;<@BBD9@<<@24>C8?BBDDDB>BD?3
@8SQ
CTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGTGTCACTCTTCTGTGTCGGTGG
+
CCCFFFFFHHHHHJGIJJJJJIJJJJJJJJJJGHGIIJJFHIJJJJJJJJHHHHHHDEFFFEEEEDCCDDECDDDDDDD######################
@8SR
GAGATCTTCACGCTGGGGGGCTCCCCGTACCCCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTG
+
B@@FFFFFHHHHFIJD=GHDB1BBDDB3BBD@ABBDDBDCBDCDDDAB@B?BBCCCCD>AACCDDCCACDBB>B-80?19@<<@B(::8<A7<<B><0<?9
@8SS
GAGATCTTCACGCTGGGGGGCTCCCCGTACCCCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTG
+
CCCFFFFFHHHHHJJJJJJDDDDDDDDB@BDDDDDDDDDDDDDDDDDDDDBBDDDDDACDDDDDDDCDDDDDBDDDDDDDDDDD?CCDBDBDDDDD35@CC
@8ST
GAGATCTTCACGCTGGGGGGCTCCCCGTACCCCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTG
+
BC@DFFFFHHHHGIIIJJJDDDDDDDDDBDDDDBBDBDDDDCDCDDDDDDBDDCDDDEDDDDDDDD@CDCDDDDB?BDDDDD@BDDDDDDD<A@BBBB?33
@8SU
GGAATAGGAACTAAGGTTTTCCTCCACGGCTTGCTCAGGGCTGCCAGACACTTTTCCTGGAGACACCATTTGGTTCTCAGAACTTCCTGGGCTCTGGGAAG
+
CCCFFFFFGHHHHJJJHIIJJJJJIIJIIJJJEGGGEGIJEGGGIEGIIGHIIJJGIIGIHGCEFED?DED;CBA>CCDCDCCCDCCACCB?C?3>@C?C@
@8SV
CACGGCTTGCTCAGGGCTGCCAGACACTTTTCCTGGAGACACCATTTGGTTCTCAGAACTTCCTGGGCTCTGGGAAGAGCTTGAGCAGTCCAGGTCAGCCA
+
@@@DDDDDAFFD?EHIG>CBH@E9@FBFIIIBGBECFG>DFGIB8BGEC;=CCCHGGGEGIEHFCEHEDECBCC@C1?ACCA955>:<:?C(5?:A>CCCB
@8SW
TCTTCACGCTGGGGGGCTCCCCGTACCCCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACA
+
@C<DFFEDFDHHDHGDDDDDDDB9@B?CDDDDD6CDDDCDDDD8?<@B<CACCDACCDDDCDDD:?ABBB>BBBABBB<??CCC?B8<809@BBDCCCAAA
@8SX
ACTTCCTGGGCTCTGGGAAGAGCTTGAGCAGTCCAGGTCAGCCAGGGCACCTGGGCCAGAAGGCCCGCCCCACACCTCAGCACTCTGGGGGGCAGGATGGC
+
CCCFFFFFGHHFHIJJJJJIJJJIIJJIJJEEHJIJIHIJJJJGIJIJJJGIIIJJJJ?HGGHHHFFDDDDDDDDDDDDDDDDDDDCDCDDDBBBBDCDDD
@8SY
CTTCACGCTGGGGGGCTCCCCGTACCCCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACAC
+
CCCFFFFFHHHHHJDDDDDDDDDDDDDDDDDDDDDDDDCCDDDDDDDDDDDDEDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDCB
@8SZ
CTTCACGCTGGGGGGCTCCCCGTACCCCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACAC
+
CCCFFFFFDGHHGGBBBBBBDD@@DBDDB6@BDDDBCDDDDCBDBBDBDDCDACDCDDACCDDCDBB7>BBBB<9<>BDDC:C?BA<ADBD-<8>>4:@C1
@8T0
CTTCACGCTGGGGGGCTCCCCGTACCCCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACAC
+
@@@FADFFHHGDHDBD6BDDDD6B@BDDDDB&6CCB3@>AC@BDDDDDDDDC3>CD<:>ACCADCA?;BDB<@ABD@@?BCCC?BB2<99>>3?CCCCCCD
@8T1
CTTCACGCTGGGGGGCTCCCCGTACCCCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACAC
+
CCCFFFFFHHHHGJDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDEDDDDDDDDDCDDDDDDBDDDDBDDDDDDDDDDDDDDDDDDDDDDDDDB
@8T2
GGCGAAGTGGCCACTGCTGCGGGAGCACAGACCCCACCGTGCCGGCATTCCTCCTCGGCTCCGGGCGGAGGCTCCGCTTTGAATTCTTCACCGGCCCCGTG
+
?1?+=@A+<DDD;FFEIFIIIIIFFFAGAE;FFFIIII>6@EFF<B@BCCE@AB;?=BB##########################################
@8T3
CTAGGGTCTCAGAGGCGGGGGTCACTCTTCTGTCTAAGGAATAGGAACTAAGGTTTTCCTCCACGGCTTGCTCAGGGCTGCCAGACACTTTTTCTGGAGAC
+
@@@DDDDDFFFFFIIIIID'939?>>>:@>:3,;A@B:<38(3(8(8(+3339+:>B(:@>?BB2;B##################################
@8T4
CCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGTCACTCTTCTGTGTCGGTGGGCG
+
CCCFFFFFHHFFHIJIFIHGIJJIJIIIIGHGEHGIGIIIIJIGIHIJIGHJHAAEEFBBCFD>CEDDC@CBDBDD#########################
@8T5
CGTGCCGGCATTCCTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAA
+
B@@FDDFFGHHG?FHIJIJJJIJJIEH?DGHAEFEGFHIIIIDHHGFFFFEEEFEDCBDDDBBBB;BBB?C@CDDDDDDDDDDDD<@2<BCAACDCCDDC3
@8T6
CTTCTTCCTGAGGACTCAGGGCCATGGCCCTGCCAGCCACCAGGTGGTTGGTTGGGGCTGTGCTCCAAGGAGCCGAGGTGTGTGCACAGGTAAGGGTCTGA
+
@@@DDDDDF<FF;A@BFACBE;AFHE93?FDC?):DGD???D@FGCD-<('-=@E<A>9B6>;A>6.->?B;<(;B8558:8?2@>ACC?@>CCA??####
@8T7
GCTGGGGGGCTCCCCGTACCCCGGCATCCCCGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACC
+
CCCFFFFFDDDDDDDD:BDDDDBDDBDDDD(67:BDBD?@BBCDDCCCDCCC?CDDDCDBDDDBDDDDDDDDDDDDDDDDDDDBBBDDCCCCDDDDDBDDD
@8T8
CTGGGGGGCTCCCCGTACCCCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCT
+
8;=?D)@63;=<<30&022>?3:55:>8=8AAA=A??==<=AA3>38>A>AA>>AA>9=8757=????>?>?>AAA????19>????AAAAAA??>59>?#
@8T9
CTGGGGGGCTCCCCGTACCCCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCT
+
CCCFFFFDDDDDDDDDDDDDDDDDDDDDDDDCDDCDD?BDDDDDDDDDCDDDDDDDDDDDDDDDDDDDDDDDDDDDBBBBDDDDDDDDDDDDDDDDBBDDB
@8TA
CTCGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCT
+
CC@FFFFFHHHHGJIAHEGIGJIGHGHIGGIJGIJAFGDHHEGDHB=;AH=<A;CC@CDDBBDDCCCCCDD<<ACDDCACD:@?CDBDDDDC@CCDDB9?C
@8TB
TTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGCCACTCTTCTGTGTCGGTGGG
+
???DD<DADDDDD3ADEI6D1?@DEIDADD*9?DD4BCBDIADCIEECDC9ADDDDDDDDDAA@@A;?AA###############################
@8TC
TTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGGCACTCTTCTGTGTCGGTGGA
+
@CBFFFFFHHGHHIIIJIIICHGIJJIJIJGIIIJGIIJJIJIJIIIJGEIHHGG@CEFFFDEEDAC?CEDDDBBDB7&0&&5<99A:4>>ACC>@D9@@#
@8TD
CTGGGGGGCTCCCCGTACCCCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCT
+
@CCDFFD@6;<8?B7B6<BCB:67:BCCBCC@CCCBBBBCBCCCCDCCCC9?CCCCAC8<B;-802()50&8<ACC?BA?A<@@>B@C9:3>A?8<<<<>>
@8TE
CGCAGGCTTCCTTAGGGATTGCACCAGGAGGCGAAGTGGCCACTGCTGCGGGAGCACAGACCCCACCGTGCCGGCATTCCTCCTCGGCTCCGTGCGGAGTC
+
CCCFFFFFHHHHHJJJJIIJJJIJJJJJGJJIGIGIG@HIJIIGGDIIJEEECDDDDDDDDDDDDDDDDD>BDDDDDDDEDDDDDBDDDBD@28>B>9@29
@8TF
CTGAGTGCCATCTGCTGGCACGGGGGTGCCCACACCCGCAGGGCAGCCCAGGGCTTCGCCAGGCAGACCCTGCAGGGGTGCTCCTCCGCAGGCTTCCTTAG
+
@@@FDADDFFFDDGHF?C@EGGBGBAF<DG@;C55;::?BD@B;;38??B?BB<(2<77;B;8<?BB##################################
@8TG
GTCTGAGTGCCATCTGCTGGCACGGGGGTGCCCACACCCGCAGGGCAGCCCAGGGCTTCGCCAGGCAGACCCTGCAGGGGTGCTCCTCCGCAGGCTTCCTT
+
@@@FADDD?FFHDIJGIIIGGIGGIJII:;@FHIG@HHF?DDDDDB<?BB@BDDDDBBD@DD@D<BDB7A<ACCB9>A<BB<<CDDDDCDBD>>BBDCDDA
@8TH
GCTCCCCGTACCCCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATG
+
CCCFFFFFHHHHHJJJIAGIIJJIDAHGIIIHDCGGGGEGHIFHECHGHG@DAEBBBADEBDDDDDDDDD?BBDDDDBDDDCDDDDD8@<BDD3A@CCCBC
@8TI
CGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGTGTCACTCTTCTGTGTTGGTGGGCGTCC
+
CCCFFDFFDHFGGIJA@EGGHGIEIGGHHIJIG>FDGFBFGC=AGHHIJJGAC>CEE)=B@CDEDCCC?B=?B############################
@8TJ
GCTCCCCGTACCCCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATG
+
CCCFFFFFHHHHHJJJJJJJJJJJGIJIJJHJJIJJJJJJJJJIIJJJJJGGFHFFFDDEDDDDDDDDDDDBDDDDDDDDDDDDDDDDDDDDDDDDDDEEC
@8TK
GCTCCCCGTACCCCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCGACTGCACACACGACCTGTACATG
+
@C@D;BDDHHFFHFFGEGICIGJGIGGG?B8B;@?FG@<=BGGH@FF47==D=BEE1;568>B?89CCDA?9?159&&)05)(4:CB@B<@##########
@8TL
CTCCCCGTACCCCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGA
+
C@@FFFFFHHDHHJJJIJIJJEHCFH>GI?BFGIIGHGDFHGGIEIIAEDAEE>DBECABDD@B@CCCDD@BDDDDB@BDCCCDCDDDBBBD>?CCCDDC@
@8TM
CTCCCCGTACCCCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAAGGCCACCGCATGGACAAGCCCGCCAACGGCACACACGACCTGTACATGA
+
???DDDDDDDD<C:@EAEEID39C*9*?BADDD?DIDDEII@=;ACAE)@C)(-(=?@@/3,,((;AA==?##############################
@8TN
CTCCCCGTACCCCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGA
+
B@CFFFFDFHGHHIJJ<FIIJJJJJJJJJIJJJJCHHEGGIIJCFHJJJI>EEHFFFDECDDDDDDDCDD?BBDDD@BBCDD@CCABBB@BDBDCCDDEDC
@8TO
TAAGGTTTTCCTCCACGGCTTGCTCAGGGCTGCCAGACACTTTTCCTGGAGACACCATTTGGTTCTCAGAACTTCCTGGGCTCTGGGAAGAGCTTGAGCAG
+
@@CFFEFFHHHGHJHGHIJJJIIAFGFHIGGIIJEG<FBFGEGHGIHGGHHCHIJJIJJHCCAEDFDDCDECCECEACCDBDDDCCC9?<9?C@CCDDDC9
@8TP
TCCTTAGGGATTGCACCAGGAGGCGAAGTGGCCACTGCTGCGGGAGCACAGACCCCACCGTGCCGGCATTCCTCCTCGGCTCCGTGCGGGGGCTCCGCTTT
+
@CCFFFFFHHHGHIGIJJJJJJJIJJIJABHGIJJJJEHIJJJJEHFEFDCEEDDDDDDDBBB<;@77BACEDDDDDDDDDDDB<?###############
@8TQ
CCCGTACCCCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGGCAAGCCCGCCAACTGCACACACGACCTGCACATGATCA
+
@@@DDADDHHFHH>@GHGB>DHI@GG)B=FB?9?4?DH?F;BF>F@@AAA;:AEEDDCA<(;(,;8?BBBBBBBB@>AC:>@ABBBBBB<A##########
@8TR
CCCGTACCCCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCA
+
CCCFF:DDDHHGHIIIIIIIHIIGGHFHIIIIIHGIIIIIIIIIIIIIIIGFHHADEDDDDDACDBA??ABDBBDDCDAACCBBDD@BDDDACCDDCDDDD
@8TS
CACAGGTAAGGGTCTGAGTGCCATCTGCTGGCACGGGGGTGCCCACACCCGCAGGGCAGCCCAGGGCTTCGCCAGGCAGACCCTGCAGGGGTGCTCCTCCG
+
CCCFFFEFGHHHFIIIJJIHJJJJJJJJJIIJIJJJJJJBHHFFFFBDDDBDDDDDDDDDDDDDDDDBDDDDDDDDDBDDDDDDDBDCB@B59?CCCDDDD
@8TT
CACTGCTGCGGGAGCACAGACCCCACCGTGCCGGCATTCCTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCG
+
CCCFFFFFHGGHFIIJJJFIGIJIJJJJIEIGHIJJBGHIHHFHEFFFDDAB;??BBBD<CDDCDDBDDAAADECCDDDDCB9?BBB@?@B79@<09:@C9
@8TU
CCCGTACCCCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCA
+
@@@FBDDBD?FFDAGFEA<FGGDBDGBGB;F<BBF>>B89==FC3C@66;;5;A5?<>><BB:CCB??B22;9&)2>AC@C@?@BBDBB5CDC:C@A:::>
@8TV
CTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGGCACTCTTGTCGGTGGGCGTCCCG
+
@@CFFFFFHHFBFGIEG?EEHIEGGHIIDEGCHIJDGHGIFIGIGIGGGIEE=AEHHFBFFEDCDEDEEDDDDDB##########################
@8TW
CAGACCCCACCGTGCCGGCATTCCTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTC
+
BCBFDFFFGHFHCFGJJJIGIGIEIJIIIJIHIJFBFGIBHGBCEFFFDDCDDDDDCDDEEDDC@BBDDDDBD<BBD@>8ACCDBB@<?AA?DDDCBAABC
@8TX
CCCGTACCCCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCA
+
@BCFFFFFHHHGHEHJJJJIIGIFIJIIJJJJIJIIGIIJJ<FGEHGIIGEHHHHFFDDDDDDDCBDDBDDBDDBDDDDDDDDDDB>BDDDCCDDDDCDDC
@8TY
GCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGA
+
@@@FDDDDDAHDFFFGEHAG:GHEG4BGFGG<FBF?@;?AGFCF>@A8<5;>;@>>>@B:@CDD>@?999>(@>:CCCDC34<82>(4:@:CCD(99:>C4
@8TZ
CCCGTACCCCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCA
+
CCCFFFFFHHGHHAFHIJIJJHIHIJI7GHJIIJJGGIJJJIII<CH>FHIHHHHFFDDDDDDDDDD<BBBDDDDDDDDDDDDDB>BD@@CDCD:CCCDDC
@8U0
CCCGTACCCCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCA
+
CCCFFFFFHHHHHJJJJJJJHJJJJJHIJJJJJJIJIJIJJJJJJJJJJJIHHHHFFDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDCCDEEDDDDD
@8U1
CACTTTTCCTGGAGACACCATTTGGTTCTCAGAACTTCCTGGGCTCTGGGAAGAGCTTGAGCAGTCCAGGTCAGCCAGGGCACCTGGGCCAGAAGGCCCGC
+
C@@FFFFFHHHHGJJJIGGIGHIJIIJIJJJJJIBHJGGDFFHDFGHIJJIHIDIIIJIJJJJHHIIIBHHGEHFFDFFDDDBDCA?<BBDDBCA9AA@BB
@8U2
CCGTACCCCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCAT
+
@CCDFFDFHHHGHJJJIIJIJIIJJIJJJIJIIJJJJIIJIJJIIIGGIHGIHHHFFDDDEDDDDDABDDDDDBDDDDCACBDDBDDDDDCCCDED@CDCC
@8U3
CACAGGTAAGGGTCTGAGTGCCATCTGCTGGCACGGGGGTGCCCACACCCGCAGGGCAGCCCAGGGCTTCGCCAGGCAGACCCTGCAGGGGTGCTCCTCCG
+
@@@DDD:ACAA8DFHIIGABFHB?FCCFFAE@9CD?@H@EBABDDD?=?</>=B';??0(2??A?;<<AC99@?@BBB?BA?A##################
@8U4
CTCCGGCATTCCTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGG
+
@B@FFFFFHHGGHJIIIIIIJIIHHHI>GGGBGIIJJJGGIIIGIJHHHHCHHFFFDCCB?BDBDDD<ACDDDDDDD<A9>C::?BD@CDCDCCC@CAAAB
@8U5
CACGGCTTGCTCAGGGCTGCCAGACACTTTTCCTGGAGACACCATTTGGTTCTCAGAACTTCCTGGGCTCTGGGAAGAGCTTGAGCAGTCCAGGTCAGCCA
+
BBBDDFFFDFHFHGJJIIIJJGGGGIJIIJJGIGHHGGGG@DGCGGIEH@CCGHGIGIJJJGHFFEHFFFFDEEEEDDBCDDDDDCCCCCDCDDCCDDDDB
@8U6
GTACCCCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGC
+
C@CFFFFFHHHHHJJJJIJJJIJJJJJJJJJIJJJJIJIJJIJJJJJIGGIJHHFFFDDEEEDBDDDBDDDDDDDDDDDDDDDDDDDDCDDEECDDDEDDD
@8U7
CGGCATTCCTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTC
+
CCCFFDDDFDHHGIJJIIJJJHIBHJFHFGGHIGGDGIIJIJIICHHIIJIHHFFFFDBCBB8=<CDDDDCDDDD@CCCACD?ABC:ACCDC@A<AA<?##
@8U8
CCCCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGG
+
CCCFFFFFHHHHHJJJIJJJJJJJJJJJJIIJIJJJJJJJJJJJJDIIJJHHGGFFFFFDEDDDDDDDDDDDDDDDDDDDDDDDDDCDEECDDDEDDCBDB
@8U9
CCCCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACACGATCATGCGGG
+
;@??DDD?DFHHFGD<;BDFGIDGCGHGG>DG<B@DH<<B9B@0@55-;D;A/:B@@D@(6(;?;;8;=@??CC4><8-00<B59:>4>((08?<AA####
@8UA
CTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGTGTCACTCTTCTGTGTCGGTGGACGT
+
CCCFFFFFHHHHGJJJJHIIJJJJJJJJIJJJIJJFHHIJIJJJJJJJJJIHCHHHHFFFFFEEEEEEEDDDDDD)553>@CDCC################
@8UB
CCCCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGG
+
<@;DDDD:@CFFFFBGDEFGEEEFFGEIII4DE9?F@BC<?8(.<@C;@E;AEE(;?DDC2(5;>BBB=@:?4:@3++59@B7><4@@:@AABB#######
@8UC
CCCCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGG
+
CCCFFFFFHHHHHJIJJGJJBHIJJJJJJJJJJJJJJIJJJJJJJIIJJJJHGHFFFFFDEDDDDDDDDDDDDDDDDDDDDDDDDDDDEEDDDDEDDDDDD
@8UD
CCCCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGG
+
@C@FFDDFHHHHHJIJJHHIEGHIJJJJIEIHGGIGIIGIIDGGGGI1CGA<BADFBDEDCAA?BBB@;@CCCCDDDDDDBBBBDCACEDDDCCDDDCBBB
@8UE
CCCCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGG
+
CCCFFFFFHHHHHJIIJJJJIJJJJJJJJJIJJJJJJJJJIIJJJJJJJJJHGHFFFFEDEDDDDDDDDDDDDDDDDDDDDDDDDDDDEEDDDDEDCCBBD
@8UF
CCCCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGG
+
CCCFFFFFHHHHGJIJJJJJIJJJIJJHGIJJJJJIJJIJJIJJJJJJIIIHHGFFFFFDEDDDDDDDDDDDDDDDDDDDDDDDDCDDEEDDDDECDDBD>
@8UG
CCCCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGG
+
CCCFFFFFHGHHHIHIJJJJHJIJJJIJJJEGGIIIHJJIIIIJIIJJJJIHHGFFFFFDEDDDDDDDBDDDDCDDDBDDBDDDDAACDEDDCDDCCCBB<
@8UH
CCCCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGG
+
@@?DDDDAFDH?AFHIGGIB=BEGHDHI@DBGHCHGDFGDBFG6@;FCGI<EEH=@3?BAA?CBBBBBBBC?C@>>A?>@BBBBC+4::CC:>CDCC@BBB
@8UI
CTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGTGACTCTTTTCGGGGGGCGGCCCG
+
CCCFFFFFHGHHHJJJJGHIJJIIFJJJHHGIIJJGHGHIIJIJIGHAEHEGCHGHHFFFFFBCCEEEEDDDDD@##########################
@8UJ
GGCGAAGTGGCCACTGCTGCGGGAGCACAGACCCCACCGTGCCGGCATTCCTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTG
+
C@CFFDFDDHFHDFHGIAHGGBH@DGGIGEGHFDGIGIGCGIIFBBCCCC@@CCCC=B?BBBBAB@B>8&+3@@C><@B?CCA>CCDDCACC#########
@8UK
CGCCACTGCTGCGGGAGCACAGACCCCACCGTGCCGGCATTCCTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJHJIGIJJIHHHHHFFFFDDCDDDDBBDDDBDBCDDDDDDDDDCDEEDEE@CDDDDDDDDBABDBD7B?AC
@8UL
CCCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGA
+
=??DDFFDFDFHDCEHEDEHEHBHIGF@GDF?CGEB@D?@G?6?6;CH@;;4A;2??7?;?C=<;B:?BCCCCC>?<>B>>><9:44>>>@CCD:>C<9@B
@8UM
GCCATCTGCTGGCACGGGGGTGCCCACACCCGCAGGGCAGCCCAGGGCTTCGCCAGGCAGACCCTGCAGGGGTGCTCCTCCGCAGGCTTCCTTAGGGATTG
+
@@@DDDDDFDFFFEGEB1?@8@DFFCFFCFIFFBD@<B(3=?B?BBB89?99<@@BB8?8@@8??B@BA<35>9@A>>>9?<@B3-&<B?@##########
@8UN
CCCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGA
+
CCCFFDFFHGHHHHIJGIIHGIJJIJJIJIJJGGIIIIJJGIJJIGIJJJHIHHHHHEFFFD@CDDDDDDDADDCDDBD@BDDDDDDEEDCCDDCDA@BB5
@8UO
TGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGTGTCACTCTTCTGTGTCGGTGGACGTCACGGTAAGGACACGGTCCAGGGCCTCCACC
+
@BCFFFFFHHHHHJJJJJJJJGHJJJJJJJJGHIJJJJJJIJJE'93;;>C;>C;>(55::;@3<@148052<0<(2<:A:(3209(2<4:C&2<<<B3?B
@8UP
CTCGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCT
+
CCCFFFFFHHHHDGHEGCFFHIIG<GH@DDFHDFHCGIIGIC=AF@@DBH?>C1;@>@BBBBBCCCCCCCB<8ACCC@CCCCAACCBB899ACA@CCB>A?
@8UQ
TGCTCTCAGGAGCAGAGGTGTGTGCACAGGTAAGGGTCTGAGTGCCATCTGCTGGCACGGGGGTGCCCACACCCGCAGGGCAGCCCAGGGCTTCGCCAGGC
+
CCCDFFEFHHHGHJIGHJCGHIGIIIIGIJIGGHIIIIIIEHBGGIIJIJJJI>FH=FHHHGB;=BDDDDBDDDDDDBBDDDDDDDDABBDA8?BDBB>B?
@8UR
CCCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGA
+
CCCFF?@DHDF8DDDGGI;AE@EHHIIIHHI@HID@DHGGIHB<AFFHAFG6A?AHHFBFFCCCCB?=8>?CCCCCCB><BBBCCCCDDCCCCE#######
@8US
CCCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGA
+
@?@DDFFFGHHHDIIHE3AFHGGIIDCGGGI>FGE<DGEHIJIE<7<G9AEHBEECA?BDFD?>B@?BD>5:ACCDDDD<BD>9@CDEEDD##########
@8UT
GCCACTGCTGCGGGAGCACAGACCCCACCGTGCCGGCATTCCTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTC
+
@@@FDDEDHHHGHDEHIJJJFGDGGI=FFHIJJJIJJIJFHHHHHFF:AB=ABB=?BDB=B2?CCCDB>>B34@A>CD>@>4><BDDDDB<<@B@)&29@@
@8UU
CCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGTGTCACCCTT
+
@?@DDDFFGGHHHJFIBHCFGIIEGBGEHIIII=GGIH<HBHHEGIIJICHEHHHHGFFFDDFCCCDBBDCDDDCC@??C?ACC@CBBDB@##########
@8UV
CTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGCGCACTCTTCTGTTTAAGGAATAGG
+
@@@DADDFHFDBFGH<DCFH@FFG>HGC9B<?G9DHGBFA>BHHGHIEHIIH?A3=CDD:767>CCAC@C=?@B###########################
@8UW
CCCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGA
+
@C@FFFFFHHHHHIJJIJJIJJJJJJJJCFIJIJIJJJJJEGEH@FFHHHHHFHFHHFFFFCDDDDDBDDDDDDDDDDDBDDDDDDDEDCCDDEDDC9@B<
@8UX
CGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGGCACTCTTCTGTGTCGGTGGAGGGCACGGGAAGGAC
+
CC@DFDDFDHGHHJGJGGEHHJGGIBGIIIGIGGIIIJJIFHIJIIJJIIDBGFHEFFHAHE@######################################
@8UY
CCCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGA
+
CCCFFFFFHHHHHGIJJJJJJJJJJJJJJJJIJJJJJJJJIJJJJJJJJJGHHHGHHFFFFDDDDDDDDDDDDDDDDDDDDDDDDDDEEDDDDEDDDDDD@
@8UZ
GTGCCGGCATTCCTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAG
+
CCCFFFFFHHHHHJIGIGHEIIIIGFHGEGGHHJGHGBGHIGFHHHHHFFBFFFDDBBBDD?BBDB;><CCCABDDDDDDDCDCCBDDDDDCDDDDDDCCD
@8V0
TCGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAATGGTCTTCTAGGGTCTC
+
=@8?DDDDAAC:@:F::CFGBD<:?BFB9BG9BDFGGG@@@B@5@6@88?=,,.6>C?B=BB:;((;:58(8@>@(4>>A#####################
@8V1
CCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAG
+
CCCFFFFFHHHHHJJJJJGIJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJGIJFHHHHFFFFDDDDDDDCDDDDDDDDDDDDDDDDEEDDDDEDDDDDBDB
@8V2
TTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGTCACTCTTGTCG
+
CCCFFFFFHHHHHJJJIIJJJJIJJIJJJCGIJJJJJJJJIIJIIIIIJJHHJHHHHHHFFFFDEEEEDDDDDDCCDDDDDDDDDDD##############
@8V3
GGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGGTACTCTTTTTTTTTGGGGGGGGTCCC
+
@CCFDFFFHHHHFGGIHHJJJJJJIEGGIECHDEH>DHHIJJJIEHJJICCDHGE??HEBDFFFFDEDCDD##############################
@8V4
CAGGCTTCCTTAGGGATTGCACCAGGAGGCGAAGTGGCCACTGCTGCGGGAGCACAGACCCCACCGTGCCGGCATTCCTCCTCGGCTCCGTGCGGAGTCTC
+
@@@DDAFFHHGHHIGIIIGIIIIIIIIGIIIIIH?FGIICHEHIIIIIIHFCABBDCDDDDDDDD:<<@B;@BD<CDDACDCC59?BDD############
@8V5
CCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAG
+
CCCFFFFFHHHHHIJIJJIJGGIJGHJJIJIHJJJJJIIGHIJIIIJJEHEEGHHHHHFFFFDDDBDDCDDDDDDDDDDDDBCCDDEECDCDDCCDDDD35
@8V6
CGGCATTCCTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTC
+
CCCFFFFFHHHGHJJJJJJJJGHIHJEHFEHIIGGHIJIGJIJGGIGHIIGHFHFFFBBDDD?B@DDDD;>>;BC@CCDDDDAABCDCCCDCCCACCDDA?
@8V7
CTTCTGTCTAAGGAATAGGAACTAAGGTTTTCCTCCACGGCTTGCTCAGGGCTGCCAGACACTTTTCCTGGAGACACCATTTGGTTCTCAGAACTTCCTGG
+
CCCFFFEFHGGDFGIIIIJCBHIIJJJGGIIGIJIGGGBGGHJBED@DBEC;B@;FHDH<@ACA;C7??3;BC(;@CDBDDD@C??@C@>CCDCCDAACC?
@8V8
CCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAG
+
CCCFFFFFHHHHHJJJJIJJJJJJJJJJIJJIJJJJJJJJJJJDGHJJJJIJJHHHHHFFFFDDDDDDDDDDDDDDDDDDDDDDCDEEDDDDEDDDDDBDD
@8V9
CCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAG
+
CCCFFFFFHHHHHIJIJJJJJJJJJJJJHIJJJJJJJJJJIIIJJJHIJIHIJHHHHHFEFFDDDDDDDDDDDDDDDDDDDDDCDDEEDDDDEDDDBDDDD
@8VA
TGCACAGGTAAGGGTCTGAGTGCCATCTGCTGGCACGGGGGTGCCCACACCCGCAGGGCAGCCCAGGGCTTCGCCAGGCAGACCCTGCAGGGGTGCTCCTC
+
CCCFFFFFDFHHHJGIJJJJGIJJJJIJIIIGIIEGIJJJJEEDFFFDDCDDDDDDDDDDDDDDDDDDDDDDDDDBDDDDDDDDBDCDDDDDB&5<C>@CD
@8VB
CAGGAGGCGAAGTGGCCACTGCTGCGGGAGCACAGACCCCACCGTGCCGGCATTCCTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCT
+
@BCFFFFFHHHHHIJIIJJJJJIJJJJJJJIJJIIJJJJHHHFF?BDDBBDDDDDEDDDDDDBDDDD@ABBDD>B?CCDDBDDBBACDEE@CDDDDC>BB#
@8VC
CCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAG
+
CCCFFFFFGHHHHJJJJIIJJJJJJIGIHIJIJJIIJJJJJJJ0BFHIIJIIIHHHHHFDFFDDDDDDDDDDDDDDDDDDDDDDDDDEDDDDEDDCDDDBB
@8VD
CGGGAGCACAGACCCCACCGTGCCGGCATTCCTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGC
+
CCCFFFFFHGHHHIIIJIJJHHIIIJJJJJIJJJJJJJIIIIJIGHB<B9==CCCD@8?BDCC>>CADD>CCC;B8?3?9(+)09<B8>@@C>B>B?>:C:
@8VE
CATCTGCTGGCACGGGGGGGCCCACACCCGCAGGGCAGCCCAGGGCTTCGCCAGGCAGACCCTGCAGGGGTGCGCCTGCGCAGGGCTCCTTAGGGATTGCA
+
@@@D=?D?FFCF+<CA1:&7@6BB?<<@65000&52<<?BBB@?B7<<905<?50<@B@8(89??(>8;@###############################
@8VF
GGCCACTGCTGCGGGAGCACAGACCCCACCGTGCCGGCATTCCTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCT
+
CCCFFFFFHHHHHJJEHJGJJJIIIIJJIIJDHHIJIGHHHHHHHFFFFDCDDDDDDDDD<B8AACCDDDDDDBADDCEE:@CCDBB?<?08?9>95<09:
@8VG
CCGGCATCGCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGAGGGAG
+
CC@FFFFFHGHHFHIGIIGIIJJJJIIDDHEHIEIJJIJIIJJAHGIJJGIHEHHEFB9B??BDDBDDDDDDD:8?9>DD@BC>:CDCCCDDDDD(4>?B#
@8VH
CCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAG
+
CC@FFDFFGHHHDHGIIJHIFGIJJJIJIBCGIEGGGEHIGGEHIJJJGIHIJGHHHFEBDDDDDDDDDDDDCDDDDDDDDBDCDDEEDDDDDACCD@BBD
@8VI
CGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGTGTCACTCTTCTGTCTAAGGAATAGGGA
+
CCCFFFFFDFFHHJJIIJJJJIJJJJHIIJGJFCGIGIG>GHFGIIIJJJGHEHFFGHFFBDFCEECEDDD@@############################
@8VJ
CCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAG
+
::=BD@D:AD??:<?DE@1AFFID@9E?EIIIIDEECDIIIID<CDIC;@;AD97.?A??7=<??:??::A>>:589&0&0)9AAA:>A############
@8VK
CTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGTCACTCTTCTGTGTCGGTGGACGTCACGGTAAGGACACGGTCCAGGTCCTCCAC
+
CCCFFFFFHHHHHJJJJJJJJJGHIJJJJJJIFHIJIJIJJJJJH'5))(+3>@CAA>@@A>575?>(4505<<9@+8?######################
@8VL
CCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAG
+
@@?DFDDEFFFFFGFBF=EBDHIGGGHDDDDBFBCAGHGBHBBBEGIEF@;BDEEEEE@=;;=>8;=BCCCCCCB89BBB9>CCCCC(4>CC@C>CBCB59
@8VM
CCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGTCACCCTT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJHIIIJBHDGGHIIGIJJIGIJIJJJGGHHHHFFFFFFCDEDD=A?DDDDDDDCDDDEDDDBBDDB##########
@8VN
GGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGG
+
BCCFDFFFHHHHHJJJJJJJJJJJJJJJJIJJJHIIJJIJFHIJJIJJJJHHEFHFFFFFEEEEEEDDDDDDDDDAACDDDDDDD>ACDEDDDDDDDD###
@8VO
GGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGTCACTCTTCTGTCTAAGGAATAGGAACTAAGGTTTTCCTCCACGGCTTGGTCAGGG
+
CCCFFFFFHGHHHJIJJJJJAFHHIIIIJJEGHJIIEIJIJJJ/8)0+3999A9::>>>:A@C3?>A@C(:1:>A4?(4>@4>@>AC<2<9<B########
@8VP
CACTGCTGCGGGAGCACAGACCCCACCGTGCCGGCATTCCTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCG
+
@@@DD?>DDHHHAGHEEGGGGHGGIIHIDHIIII<GIGHEEHHECBDE=BA???BBBBB<CCCCBBB@@CCDEECEECCCC>BBBB?@A@BBB7<BCC>C9
@8VQ
CCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAG
+
?@@FFFFDDHHFHIJGGGDHGGGHIJCHJIGGCEGIJIIDGGIBHGIJJBEHHFCHHEDFBDDCDDBDCDDDDDDDDBDDDDCCCCDDDDDDCCCABDB09
@8VR
CCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAG
+
@@@DDDD?DFHHFGF<?FCGGHCGHIGFHIGECGEABGGIGHEFDGGGAGGHAAHHCC???DCC>@BBCCCCCCB@B9@>>B?CCCDDC@AA>@@:9B99<
@8VS
CCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJIIJJJJJJIJIJGIJJIIIJJJJIJJHHGHHFFFFDDDDDDDDDDDDDDDDDDDDDDDDEEDDDDEDDDDDDDD
@8VT
CCAGGAGGCGAAGTGGCCACTGCTGCGGGAGCACAGACCCCACCGTGCCGGCATTCCTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGC
+
CC@FFFDDHFHHHGGGEHIJJIIIIJJJIGGIJJJIEGIHHFFFB?CDDD?B;BD>>ACCCCDDDDDDB<BDDDDB?CDDCDDDDDDCD@ACDEDDDD@BD
@8VU
TCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGTCACTCT
+
@BCFFFFFGHGHHJJJJJJJIIJIJIHFFGIGIIHHIJJGHGJJGIIGIGEHFHHHFDFFFFEDCEC@D=AACCCCCDDCCCCDDA@BDDDD#########
@8VV
CCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAG
+
CCCFFFFFHHDBFGGBHEEHHIIGIGIIGGEA@HIIIFG@GEH@FGII>;B;EHHHEH@DFFDCB8@5,:AA>CBDB>9595<CCDDCDC>AC@>>><@##
@8VW
CCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAG
+
CCCFFFFFHHHHHJJJJJJJJJJIJJGIIJJJJJJIJJIJIJJJJJJJJJJJJHHHHHFDEFDDDBDDDDDDDDDDDDDDDDDDDDEEDDDDEDDDDDBDB
@8VX
CCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGGCACTCTTGTTGGTGGACGGCCC
+
C@CFFFFFHFAABGGB?EHGCGDFHIIII<B@FGII>FH;@AF>CCDGII=DE=CEE@DEDEC>ACCC>ADDBDD##########################
@8VY
CCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAG
+
@<@DDDDDFDFFDGG@GGBHGHDHGGIIAG@HEHGBFEE<FBGIDHIIIIHIIFF>EADE?BC<BBBB??@@C>ABB>>BBBC:>CCDC<>CA@A######
@8VZ
CTTCTGTCTAAGGAATAGGAACTAAGGTTTTCCTCCACGGCTTGCTCAGGGCTGCCAGACACTTTTCCTGGAGACACCATTTGGTTCTCAGAACTTCCTGG
+
CC@FFFFFFHFDFIIIEAGGIIIIIII@HIHHGHEIGGD:@FGEEII@9CGE2/@@=7=@;=?EHH;;@7?@AEDC@?=A>D>>59:>:>@CC?C######
@8W0
CCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCGACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAG
+
=81+AD02CD?A2A>3AE1<+<A*???:E<DCDAD>*?DDCD0?'5-5=<,9=>3(;>?=1<=??7;<99>A#############################
@8W1
CCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAG
+
@CCFFFFFHGHHDIIIJHIIIJJJJJEEGIGIJJIIFGIBHIIIJGIJJJAHGHEAHEDDFFDDDD@BDDC@CDDDDDBDDDCCCCDEDDDDEDDCBDBDD
@8W2
CCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAG
+
@@@DDDDDHHHH<FHGGE=FG;BEB?GGGC9@GCCH@HGEGGEHB@F>FEHGCH;AHEBDEB>>>B=<>>CC@C@BB35>BBC@CCADCCCCDACC@BB5<
@8W3
TCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGTCACTCT
+
@CCFFFFFHHHGHJJJJJIGIIGIIJGFDFHJAG7BGGIFIIJJIJIGIEGHGHHHCDDFFDCCEEEDD;>CDCDDCD@?CDDECDDDDDD##########
@8W4
CCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAG
+
CCCFFFFFHHHHHIJJJJIJJJJJJJJJJJJIJIJJIJJGJJJIIJJJJJIJJHHHHHFFFFDDDDDDDDDDDDDDDDDDDDDDDDEEDDCDEDCDDBDDD
@8W5
CCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAG
+
BBCF=DDFHHHGHIJJJJIIJJIJIGHIJJJJJJIJJJFGIIJIGIJJFIJJIHHHH?BBD=>CDDDDDDDDDDDDDDDDDB?:>CCDC>CCEACDDDBBD
@8W6
CCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAG
+
?;?>ADDD:ADD:2A<AEC;;FEAEE>B9?C<C*:?DEEI=667BD?D6;@ACD??=;@=?D@@;?/<9(>>AA?>>55;59>3:>B>A>>ADA>A?3;?>
@8W7
TCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGGCCCTCTTCTGTGTCGGTGGGC
+
CCCFFFFFHHHHFIHIJIJFHJJJIIIJJIGGGIGIJGIIIIIJJIIJJIIHFHADFFFFFDEDACDCDDDDDDDD@########################
@8W8
GGCGAAGTGGCCACTGCTGCGGGAGCACAGACCCCACCGTGCCGGCATTCCTCCTCGGCTCCGTGCGGAGGCTCCGCTTTGGATTCTTTCTCGGCTCCGGG
+
@@@DDAAABCBDFG<FHG9F:EH?@GDGEGCF??6B;;F2CBGBA6A<CC>AAC?;?:<@;578?@###################################
@8W9
CCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAG
+
CCCFFFFFHHHHHIJJJJIJIJJJJJIJJJIJJJJJJJJJJJJIJJJIJJHIJHHHHHFFFFDDDDDDDDDDDDDDDDDDDDDCDDEDCDDDEDDCDDD>B
@8WA
CCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAG
+
@@@FD<DDHHHGHJJIHIFHGCGHJJIGGJJJIIGGGGIAHG<@BFGHIIDHJGBH;ADBEDCDDBDDCDCCCDDDDDBDDDD@CCCDDCDDDDDDD####
@8WB
CTCGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTTGGACTCTGTCCTGCCAGGGTCTTCTAGGGTCT
+
@@@DDDDDFFFDA@F:F1??BFGD?GF99*9?9?D8B??@FC;AF/6@'598=5;;>A>8/=?((9:5(4<3::?@#########################
@8WC
CTCAGGGCTGCCAGACACTTTTCCTGGAGACACCATTTGGTTCTCAGAACTTCCTGGGCTCTGGGAAGAGCTTGAGCAGTCCAGGTCAGCCAGGGCACCTG
+
B@BF=DFFDHHHHGIGGEHIGJGIJJJF>FHIIIJJIJIJG=HIBHIIIJAHFGHGFHFGIGHAHIIH9CEFFFDFEECACAA;?>CCCDCDBB?BDDDA?
@8WD
CCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTCCATGATCATGCGGGAG
+
@@@FFFFFGDHDDEGIIIECHGGGHJJIHI@GIAEHIFIBHIIIFGIIJIHIIHHHDED??D<AB?BBCCD3:@BBDDDDB@CC(4:@(4@:CCCC>BBD@
@8WE
CCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAG
+
CCCFFFFFHHHGGJIHGIHJJJJJIFGIEIHIIIJIGGJGGIIIJJJJJJJJGHHHHHFFFFDDDDDDCCDDDDBBD@&55<<@CDDEDDDDEDDCD<BDB
@8WF
CCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGTGTGACTCTT
+
CCCFFFFFHHHHHJ@GBGGIJGHHII3EBEHG68?FAHDFIIGG@)=EHCGEEHFF>BDEEBC@A>;?BCDCDDCDAA5:?CACDCD?#############
@8WG
CCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAG
+
@CCFFFFFHHHGHIJGGIFGGIHIGIGIIIIJJBGHJJJDGJIJIJIIJJEGIGHHHGFFBEDABBBBDDDCDCABDBDBDDDDDDDDA>CDEDAC>BDDD
@8WH
CGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGTGTCACTCTTGTCGGTGGGCGTCACGGT
+
CCCFFFFFHHHHHIIFFHIJJJIJJIHIIIJJHGHEHGIIJIIJJGGGIGGCHHHHHHHFDFFCCEAEDDDDB############################
@8WI
CCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAG
+
CCCFFFFFGGHFHGIIJIFIIGIJJIIGIIJJJJIJJGIJGHIHHIJIEIEGIGHHGCFFBBDDDDDDDDDCDDDDDDBDDBDDCCCDDDDDEDDDDDDBD
@8WJ
TGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGTGTCACTCTTCTGTGTCGGTGGACGTCACGGTAAGGACACGGTCCAGGGCCTCCACC
+
BCCFDFFFHHHHGGIJJJIJJCFHIIIIGJJFHEIJJIJJJJJB,9,(6>>;>CA@:>;:>=B258(:;&5<<9>22?>@+2(2)52<@3(9&(+28ACC8
@8WK
CCGGCATCCCTNTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAG
+
@@@DDFFFHHH#2<CBFFGHJIJJJJJIDG3?DEFHIEAG9?FIA@FGGIBBEEHHCBDF=ACDB@DBCDDDDCDB<BDDDBCCCDEEDCCCEDCDB@B@D
@8WL
CTCAGGGCTGCCAGACACTTTTCCTGGAGACACCATTTGGTTCTCAGAACTTCCTGGGCTCTGGGAAGAGCTTGAGCAGTCCAGGTCAGCCAGGGCACCTG
+
CCCFFFFFHDHHFIIJEIIIJJBHHCHIIIIGGIGIIIIJJIIIIJFEIJHIIHIIGIIJIJJ3=CHHHHHFFFFFECEEEEDDDDDDDDDDBBDD@BBDD
@8WM
CCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAG
+
@B@=AA<DFDHGHIGHIGGEHGIJJIHIID><DGGIJ<D;;8@ACGGF<ABAAEEHEFDEDDCDBBBDD?C3:>ABDDDDDBDCCDA@@>CDD:>><<BB9
@8WN
CTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGTCACTCTTCTGTGTCGGTGGGCGT
+
CCCFFFFFHHGHHJJBHFHIHJIGHIJGDGGJJDIGHIIIJIJJJJJJJJFGCCEHHFFFFF?CCCDC;CDDDD###########################
@8WO
CGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCA
+
CCCFFFFDHHHHGIFBGHIJJJJDIECIJJCGGGCFGGEGGIJJGCGGEDF1@ACCDB?@@CCCDDD>?88<9CCDCCCCCC@4??2>CCCDD>3<+99@:
@8WP
CTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGTCACTCTTCTCTGTCGGTGGACGC
+
?@?D=DDFHFFAFEIII?E@GGDH:@FGFFGFF@EGIGI@FIJCGHIGGIII=?AHH@>?@?;>CC;>ACBDBD###########################
@8WQ
CCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAG
+
@@<BDFFFHHFGFEGGGGGHGCHJIJJGFGGDHFIGI@GCEADAHHGJIGGBGEHCHEDFFFDCD?BD>CDDDDB?9>BDDBDDCDDECACCAA@A<<@<9
@8WR
CTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGTCACTC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJGHIJJIJGHJJJIIJJJJJJJJJHHHHFFFFFFEEEEEDDDDACDDDDDDDDCCDDECDDDDDDB########
@8WS
CCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAG
+
@@@DDD??DFDA<ED3EEFBCEHGGIIEBFFHBBFFGA>)8?F:BCHGBHHGHE:EE=@?BDACBBBBA:@@C:?BBBBB99?(:>:>AAACE:A>>399B
@8WT
GTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGG
+
@@@DDD:?F>CBFE:8EFADCFG@GFFIEEFF?6@F08?0@F4;-7=;C<=BDC<;6;>3;@5;?BB@>AAA>:5@@BB2><@@>(4@B3>?>4@AA?8<B
@8WU
CCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGTCACTCTT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJIJJJJJJJJJJJJJJJJJHIJJIIJJHHGHHDFFFFFEEEDDBCDDDDDDDDCCDDEDDDDDDD###########
@8WV
GGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGTGTCACTCTTCTGTGTCGGGGGACGGCACGGGAAGGAAC
+
?@@DDDDFHHFHHIJHIIIJIJJJFIJIJJEGHGIFHGI?DBFFGCCGI*9BCHGGFIGHF:2;54+>>C###############################
@8WW
CGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGG
+
@@@D?DDAHHHFDFGIHGIDCHGCHDFG@CGEGEGGIII;FH6BFBC@//';=@EFEEHFBDBA?BDCC35(:5?;>BB@@####################
@8WX
TTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGCGTAACTCTTCTGT
+
@@@DADDDFFAFF4C?FFHIGGI@GGGEGHHIHIGDGGI@BDHEIIDFCGEG;?=??AEDBDB?ACCCACC;>A??ACEC:@B<&5&&&))88@CCCA###
@8WY
CGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJIJJJJJJJIIJIJJJJIIJJJHHHHFFFDDDDDDDDDDDDDDDDDDDDCDDEEDDDDEDDDDDDDD8
@8WZ
CAGGGCTTCGCCAGGCAGACCCTGCAGGGGTGCTCCTCCGCAGGCTTCCTTAGGGATTGCACCAGGAGGCGAAGTGGCCACTGCTGCGGGAGCACAGACCC
+
@CCFFFFAFDFHBHIIGGI>FEGIBACEB<D@1BB@DHIIB8;EH>AAECC>7;;C>@A;5;>AAB9?B<5;59(+:?AC<@@CCCCBB5@BB@@C398AB
@8X0
CGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGTGTCACTCTTCTGTGTCGGTGGACGTCA
+
@@@DD?DAAFFAFF>GD?FFGDHIFDB@GGIGHGHGHGDBFHIEE@AAEDDCEHFCHHD=?BDCEACA=BB##############################
@8X1
CGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGT
+
CCCD@FDFHDDFHBAHIIGHIGIICFFGG@@BGIC<GGEADDBHGEHGJEGGGDEHFCH??BDD@;?>?CCDCDBBBBD9>C::@B@@CDDDCCC@D####
@8X2
CGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGT
+
CCCFFFFFHHHHHJIJJIJJJJJJJGJGJJIJJJJJJJGGJJGIJJJJIJJJJIJHHHGFFFDDDBDDDDDDDDBDDDDDDCDDDEEDDDDEDDDDDDDD2
@8X3
CGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGT
+
CCCFFFFFHHHHHJJJJJJJJJJJIJJIJIJJJJJJJJDHIJIJJJIJGIIIIIJHHHHFFFDDDDDDDDDDDDDDDDDBDCCCDEDDCCDEDDC@DD@@8
@8X4
CGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGTGTCACTCTTTTGTGTTGGCGGACGTCA
+
=+1+2AA<2A=AACA<:=?AA:AAAB<ABBBB<=>>>=AA>A>9=>>B7A2==>AA?AA@;>>@BB@@@################################
@8X5
TTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGGTACCCTTCTGTTTCGGTGGA
+
@@@DDDDDFDFFFIIIEI?F:?FDGEEIFD<FEF<<BFFFCACF@FE@@@DAEEEBDD?BDCBCC(;;;ABBABBBBB#######################
@8X6
CGGCATCCCTGTGGAGGAGCTCTTCAAGCGGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGT
+
??<DDDEDHFFDFGIIE7BDHFHEC<CB9)1?@FHIGD2DFFHG;F@B:=EB237?;;.;?BB;2;?CCCC:ABD>@DB35?CDAACCDCC@C>@@DB3>2
@8X7
CGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGT
+
C@@FFFFFHHHHFGEGIIIJJJIJIIJJIEGGJJIJJIIIIIJJJGIIGIGIIIJHHHGFFEDDDDDDDDDDCDDDDBDDDDDACCDDDDDDDDDBBBBD#
@8X8
CGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGT
+
@@CFDDDFHHHFFHGGGBHGIIJIJIJJJGIGGGIIGGGIIHIIIIIGHGHDHIGFFHEBBEBA@B?C?@>>ABBB@@DDDDCCDEEDACDECDCD9B>D#
@8X9
CGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCACATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGT
+
CCCFFFFFHHHFHIIJIIJGIEHHIJJIJJIIIJIIIJAHIIBHIGHIJJIIJGIGGIJFHFFBCDDDDCDDDDDDDD@BBDCCDDEDDDDEDDCDBDBD2
@8XA
CGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGT
+
@CCFFFFFHHHFHJBHIGHJJJJIJIJJJCHIJJJJJJJJJIJIBGHGIFHIIHIHHHHFFFDDDDDDDDDDCDDDDDDDDDDDDEDDDDDEDDC@DDDD?
@8XB
CGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGT
+
?<?DBD?BD?8DDE>D++3<8A<FAF@?EE<9C:DD<@?B)?0?BD(@@ADACCC>DD9;(5>@;9;>AAA::(8;9>5>>?>AAD>>3:(44>>??>99<
@8XC
CGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCG
+
BCBFFFFFHHHHHJJJJJJJJJJJIJJIJJJJIIEHJEDGGHIHHCHHHFFFDDDECCDCCDD?ABDDACDCCCDCDDDD<ACDDDCACD9ACCCCDDDBB
@8XD
CGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGT
+
@CCFDFFFHHHHFIHIGIJJJJJJGIJJJGGIJIJJJJJJIID@FGCFBHGHIHIHHHHFFFDDDDBDDCDDDDD?BBBD<CCCC@C>A@@ACDCD@<<B2
@8XE
CACGGGTAAGGGTCTGAGTGCCATCTGCTGGCACGGGGGTGCCCACACCCGCAGGGCAGCCCAGGGCTTCGCCAGGCAGACCCTGCAGGGGGGCTCCTCCG
+
CCCFFFDDFHHHDEHIGIFGHGIJJJJJGHIFIIJJJIJ'9BEEDDDDDDDDDDDDDDDDDDDDDDDBDDDDDBBBBBDB<AACCBCCD>D&5@9ABCDC@
@8XF
CCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGTTACTCTT
+
?@@DDDD?<FBD?BGG?F<@<:C@F8C88C@))0BDFHID<AC78=CD;ED26.=.=.7?BD@;AC??BCCCCC>CA?C5<@;>@@??#############
@8XG
CGGCATCCCTGTGGGGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGT
+
;@@<BADDHBAFF;8@D>@<FCGG@GHEFHA;?8??D3C=;4@CCDEEB9=BC;>CC;;==@B@B@?A?CA>38<@<@BBBCCCC>C>(:A:>@C599@##
@8XH
CCGCCGTGCCGGCATTCCTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCT
+
CCCFFFFFHHHHHJJJJJJJJIIIIJJJJIGEGAHAE5==AEDEBDAEEDCDCDDDDDD@DD?=B5<@>@BBDBCDDD9><BB@C<>>@CD<<A?C@CCC@
@8XI
CGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGT
+
CCCFFFFFHGHHHIHIFHGIJJIJII@GIIJIEGIGIIIJDGGIIGBHI;AHHIJGHDCEFFDDDDDDDDDDDDDDB9B@>ACDCEEDDC@C::@BBB7>8
@8XJ
GCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGTTACACTTCT
+
@@@DBDFFHHHHHHGJCHBFHIGI;G?CFFADHHDGGHHBFF@=C>;FAE;CEECEEH:B@D?D(,635>CAADDD:?C######################
@8XK
CGGCATTCCTCCTCGGCTCCGTGCGGAGGCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCCAGGGTC
+
@@BFFFFFHHHHHIJIIJJJIHH6EG)?0088D676@@4@FEHGGI)===:AB?>A'6;:'8'3,9>@>-505@::9@++488<ACC<@@@##########
@8XL
CTTCGCCAGGCAGACCCTGCAGGGGTGCTCCTCCGCAGGCTTCCTTAGGGATTGCACCAGGAGGCGAAGTGGCCACTGCTGCGGGAGCACAGACCCCACCG
+
@CCFFFFDFHDHFIIGJIJJHFFFGHHIICHGHJJJIGIIJJJFHHH@EHHHFFFFFCE=BBBBBBDBBBCCBDCBDDDDDCB><<@BDDDDDD?A@BDDB
@8XM
CGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGT
+
@C@FFDFFHHHHHIFIJHII@HIHIJIIIJJIJJJJJG@GGIJJIIIGGGIGIIIE=EH=DDDDDDDCCDDDDDDDB@DDDDCDDEEDDCCDDDC>BB9<2
@8XN
CGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGTGTCACTCCTCTGTGTCGGTGGGCGTCA
+
CCCFFFFFHHHGHJJIJDIJJJJJJJJJJFGGGHIIIJJJJJJIIGIJJGGCCEHHHHHF;BFEEDDEDDDDB09)4:>:@(:9@################
@8XO
CGCTTCCTTAGGGATTGCACCAGGAGGCGAAGTGGCCACTGCTGCGGGAGCACAGACCCCACCGTGCCGGCATTCCTCCTCGGCTCCGTGCGGAGTCTCCG
+
@@@FADDDFDF<CFGIIJJJJJGEHGEGIIGAB>BF?DGG<CGCHI/8BBACEED9ABBB@DBDDDDDDDBDDACCCCC<C>><?>?5(89-99>234>C9
@8XP
CGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGG
+
@CCFFFD?DDHDHGGIIDGGGGGGGGEGGEG;BGEHIEEHBE8;??CFEAAHHHEEEF?;?DD?BBBACCD@@??@B@D55A:@>CAC@>@:@C<@BDBB#
@8XQ
CGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGT
+
@B@FDFFFGHHHHJIIIGIJJJIJJIIHGIJJJIIDIJHJJJJIJJGIIJGDHIIFFHDFFFDDDDDDDDDDCDDDDDDDDDCCCDEDCDDEDDCDD<9B2
@8XR
CGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGT
+
CCCFFFFFHHHHHJJJJIHJIIJJIIJJIF3EHIJGIJCGIEBFFHIIIJJJIIJHHHHBDFCDDDDDDDDDDDDDBDDDDDCDDDEDDDDDDDDDDDDD2
@8XS
GCACAGGTAAGGGTCTGAGTGCCATCTGCTGGCACGGGGGTGCCCACACCCGCAGGGCAGCCCAGGGCTTCGCCAGGCAGACCCTGCAGGGGTGCTCCTCC
+
CCCFFFFDHHHHHFHEIHIFHHIJJJJIJIIJJJJJIJJJ;ABEFCEACDDBDDDDDDDDDDD@BDD???C@;B?BDDDBDDD?CCDDDBBD<>8::@9??
@8XT
CGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGT
+
CCCFFFFFHHHHHJJJJDHIIJJJJJJJJIIJJJJJJJIJIJIJJJJJJJJJJIIGGHHEEFDDBBDDDCDDDDDDDDDBDDDDDEEDCCDDDDCDDD###
@8XU
CGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGT
+
CCCFFFFFHHHHHJJJJIJJJJJJJJJJJIIJJJIJJIIJJIJJIJJJJJJJJJJHHHHFFFDDDDDDDDDDDDDDDBDDDDDDDEEDDDDEDDDDDD592
@8XV
CGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGT
+
CCCFFFFFHHHHHJIJJIIJJJJJJJJJJIJJJHIIJIIJJJJJJJJJJJGHJIIHHHHFFFDDDDDDDDDDDDDDDDDDDDDDDEEDDDDECCCBBBDD<
@8XW
CGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACTTGTACATGATCATGCGGGAGT
+
CCCFFFFFHHHHHJJJJIIJJJJJJJJIIGIIJJJJJJJJJJJJJJJJJJJJJIIHHGHFFFDDDDDDDDDDDDBDDDDDDDDDEEEDDDDEDDDDDDDD<
@8XX
CGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGT
+
@@CFFDFFHGHHHJJJJJJIIIJIJIIJIIIJGIIIIIJJJJJIJIJFI';DHIIHGFFFBEDDDDDDDCDDDD@DD<BDBD@CCCDDDACDDDDDBB9@#
@8XY
CCCCACCGTGCCGGCATTCCTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTC
+
@CCFFFFFHHHHGJIIJJJJJJJJJJJJJJJJJIGIIIJGIHHHGFFFDEEEEEDEEDDDDDDDBDDD??BDD@D?CDDDDDDDDDCDDDDDDBDDDDDDD
@8XZ
CTCGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCT
+
CCCFFFFFHHFHHJJIIGIGGIJJJIIIJGIIIGIIIIIIIJBGFE@CBEDED=ACDDDDDDDDDDDDCDDBDDDDDDDDDDDDCABD<CDDCACDDDDC?
@8Y0
GGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTG
+
CCCFDFFFHGHGHIIIHIJJJJJJJJJHGHIIJGIJIJDGIIGIIJJJJJIJJJJJGAEHFFDDD@CCDDDDDBB@@BBBDCDDCDCCDDEAC>@BDDD<A
@8Y1
CCGGCATTCCTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGT
+
CCCFFFFFHHHHHJJIGIGJJIHIJJJBHHIGIJGGIIJGIGIJJJJJJJHGGHFFFDDDDDBDD@CDDDDDDDDCCCDDDDD@BDDDDDDDDDDCCDDD8
@8Y2
CTGCCAGCCACCAGGTGGTTGGTTGGGGCTGTGCTCTCAGGAGCAGAGGTGTGTGCACAGGTAAGGGTCTGAGTGCCATCTGCTGGCACGGGGGTGCCCAC
+
@@@?DFDAHAHDHIIGGIFEGICFFE@GEHGBBFG4BGHGG36BGHCHHH6.;66)77;@B).;@CB2;?A>C@>:@C>ACCCCC>7ACB&5@B0529>@?
@8Y3
CCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGC
+
?@@FFADDCFDDDHIJIJJGEHHIGEHIG>GDHEFGF;BB;FGHGGG9@CC@DA@:449ABEC:>;>A(3;@=;09:>@CCC@ACCCC(05&09B<3>C@<
@8Y4
ATTGCACCAGGAGGCGAAGTGGCCACTGCTGCGGGAGCACAGACCCCACCGTGCCGGCATTCCTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTC
+
;=?DDEFDHHHHFJJJJJJGIJJJGHIDIFIHIIIFIICHHHAEDFFDDDDDDDDDDDDDDDEDDDDDDDDDDDDBDDD<9><ACCCB95>BDCCCDCDDD
@8Y5
CCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGC
+
CCCFFFFFGHGGHJJJJJJJIHHIJJJJGIJJIJJJJJIJIJJEFGIHHIGIIJJDHFFDDEDDDDDDDDDDDDDDDDDEEDCDDEDDDDDBDD?BDDCCB
@8Y6
CTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCAT
+
@@CDFFFFGHHHHJIJJJJJJJJJJJJJJJJJJJIJJJJIIJIIIIJJJGIIJHHEFDDEEEDDDDDDDDDDBDDDDEEDDDDDDDCDDDDDBACEDDDDC
@8Y7
GTTGGTTGGGGCTGTGCTCTCAGGAGCAGAGGTGTGTGCACAGGTAAGGGTCTGAGTGCCATCTGCTGGCACGGGGGTGCCCACACCCGCAGGGCAGCCCA
+
@B@FFFFFGHHGDGGHIIJIIHHDEHIHICGH@GBFDHBHIDCFCHIIIIECHGIIIIIEF>CEEFFFFFEEAD?@@9<@CC:+(28955>@BDBD@BB@1
@8Y8
CTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCAT
+
BCCDFFFFGHHHHJJJJJJJJJJJJJJJJIHIJIIIIJJJJJIJJFIIJIIIIHHFFDDDEEDDDDDDDDDDDDDDDEEDDDDEDDDDDBDD8ACDDDDDC
@8Y9
CTGTGGAGGAGCTCTTCAAGATGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCAT
+
???ADB=DB?CDD3EEE@BC+<??2CE@C?C?1DD>?6?:D@:B9B).==(5(@AA<>@AAAAA;???;88;;<4:>B>4:::4>AA##############
@8YA
CTCGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCT
+
@@@DDDDDHFDFFEG1@)?:?FCFFHH<DEGGDHI>HCCA:==8F8=;<B?8>;5-;;;@BBB:@CCACC<188?CCCAC>4:3>>?B+99ACC>3:?###
@8YB
GTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGGGCTGGCATGC
+
?=?DDDDABDBBFIGGIGE>DB?CEGHIAGGGECCCHGGGBHIGHIIGCHIEEHD>DCCCC@@BBBB=BB@?ACCE:>A@@A@:@@BB5>&0<ABB@ACBC
@8YC
GTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGC
+
B@@DFFF?HHHHHJJJJJJIJJJJJGIIFCHGIJBHHIJJJJHIJJIJJJIIHGFFFDEE;ADDDDBBBDBCDDDEEDDDDEDDCBBBDD<ACEDDDCCAC
@8YD
GGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCG
+
??@D?DDDFFFFHGHDGF>GHEH<EHHIGIGGII>GGG>CHFHI=FFGFGEAEE?@D;CCCCBB:;BBBCCCCDECC>CCC@@0993<(+:@>A?CAACC0
@8YE
GGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCG
+
@@@DDDDDFFHHFH>CCAE>E?BEDFEG>A<FF?C<AD@7?D>9B2C7;''-:?DD>D@A@C(398=;89:55:BC@ACD:C>559>528>:@A<<A####
@8YF
GTGGTTGGTTGGGGCTGTGCTCTCAGGAGCAGAGGTGTGTGCACAGGTAAGGGTCTGAGTGCCATCTGCTGGCACGGGGGTGCCCACACCCGCAGGGCAGC
+
BB@DFFFFFHHHHJJJJEHEGIJGIJICHIEGHHJ?FFGHIJJEIIICGEAGG6BCEHHEHHFFFFFFEEEECDCDDDDD@BDDCDDBDDBBB>@DD@DBB
@8YG
GGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCG
+
;;++==+=CA<?FGIBBEEFF3CDC3AFHHDHHH@DGH8DFDFGIGGIE5;AADE9BBCC3>?B@B6==C@CCEE@A:ADCC@##################
@8YH
GGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCACCTGCACACACGACCTGTACATGATCATGCGGGAGCGCTGGCATGCCG
+
=;+??=BDFFFAF>+<E3FEFFEEECFFIFEFIDFFBBDDDFBFEEB(=5-'-'.;?B3.;@?BB?=?=@>((,>::3@>A@>B>@050&0(55<?>@>>5
@8YI
GGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCG
+
@<@FFFFFHHHHHJJIJJEGIGIGAGGGHGGHGIJIJGF@@<CBCDFFGIGEHFFFFFEEEEDDBDDDDDCCDEEDCCCECCA@BB<B<A>@CDBDCA@>5
@8YJ
GAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGC
+
CBCFFFFFHHHHHJJJJJJJJJJJJJJJJIJJJIJIIJJJJJIJJFIIIIEHHFFFFFEEEDDDDDDDDDDDEEDDDDEDDDDDDDD<ACDDDDDDDDCBB
@8YK
GAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGC
+
CCCFFFFFHHHHHJJJJJJJJJJJJIJJJIJJJJJJJJJJJJIJJIIJJJJHHFFFFFEEEDDDDDDDDDDDEEDDDDEDDDDDDDDBBDEDDDDDDDDDB
@8YL
GGCGAAGTGGCCACTGCTGCGGGAGCACAGACCCCACCGTGCCGGCATTCCTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCA
+
@@CFFFFDHHHGHJJIJJIJJJJGJIJIIHGGIJJJJJJHIJJHHFDDEEEDDDDDDDDDDDDBDDDDDD?CDDDDDDDDDDDDDDDDDDDDCDDDDDDCD
@8YM
CTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGGCTCAGAGGCGGGTGTGCCTC
+
;>;<A0A=<BABBB9ABBAB7))+<?=A5:::<)7//9?>6A6=AB7>7==>A;>5>@@?@>;>@@??=A5;=????9>='5;;???##############
@8YN
CCCCACCGTGCCGGCATTCCTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTC
+
CCCFFFFFFFHHFHIIJG<GGGIJJJFIJJJF;;@@BGB@EHEHDFFDCCCEEECEEDD3@/;?BDDDB?B;@;B?CDCCDDDD@CD?CCCC?8<ACDCCA
@8YO
CCGCTCCTCGAGGAGCTGGCCATTTGGCCTGCAGCCACTTCTTCCTGAGGACTCAGGGTCATGGCCCTGCCAGCCACCAGGTGGTTGGTTGGGGCTGTGCT
+
@CCFFFFFHHHHFIIJIIGFHGGEC>FEHIIIJJJJEGIJJJIHIIBHI?FCCGHI)==?EECHGFFF<ACCCDDDDDBDB(:<8<792885<BB>@B>C@
@8YP
AGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCG
+
CCCFFFFFHHHHGEIJIFIIJJJFJJJJGIGIFHIIJJJIJJIJDHGGIJBHHHFFFEFECDDBDDDDDDDEC@CCDEDCCBDBD@?BCA:>@DDDCC>B>
@8YQ
AGGAGCTCTTCAAGCTGCTGAAGGAGGGCCCCCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCG
+
@@@DFFFFHHHHDE9AFHG@EFEG>?E1CF)?GHIII18CGCGGFEHHHF?<C>@CACCDDDD;@?@CCCCDCCCDCDD@CB>BBB8?@CCC2<@AC:<>B
@8YR
CCCCACCGTGCCGGCATTCCTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGATCCGTGCGGAGTCACCGCTTTGTGCTGGGACTCTGTC
+
B@CFDFFFHHHGHJIJJJJJIJJGIIIJFIHA???@E@G;CEEHHFFECCA@CDDEECCDC6=',3?A8?@BD;B?C3>@?>9@BD@CDC@C@?BBC:>@3
@8YS
GGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGC
+
?@@?DDFFDFFHFEHGGEHI@BG@HEFHGCGHBAHEHBGGHDGEGIHGHE:C;=@?C@DCCC?BB2<:@C>>@CCCCA439<<5>+2:@CCB?:<A3)5<B
@8YT
CGGCATTCCTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTC
+
CCCFFFFFGHHHHJJIJJJJJDHGIJFIHGIIJBHGIJIJIIIGIJGIIGAECA>D<BCDBDBD?C@>AB@@BD@>CCC@CB<ABCDCCCCCCC?@CDD<?
@8YU
GAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGGGCTGGCATGCCGCGCC
+
@@@DDDDDFFHBFAG@FGBCEHA=EGIIIIGIFGIGI<BFGGCHGEHIIF5AEHCC?BD>CBBBBC>>CDE>CCCCC@><B7<>&09A<BBC>B>@9<<@B
@8YV
TCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGTCACTCTTCTGTGTCGGTGGGCGTC
+
CCCFFFFFFHHHHJJJIJJJJJIIJJJEEGIGIJ@HIJIGIIICHIJIJIDHHFHEFGFFF?CECCE;CBDDDB###########################
@8YW
TCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGTCACTCTTGTCGGTGGGCG
+
@@CFFFFFHGHGHJGBGHJJBGHIJIJIJIIJJHIGHJIIIIJIJIJJJCADEEEHFFFFFEEEECA>??CDCCC?BBBD&0)0<::+4>>:><@.?B###
@8YX
GAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCC
+
CCCFFFFFHHGHHIJJJJJJJJIJJJIJJJJIJIJIJJIJIHGJJGIIIJHHGHHFFFFDDDDDDDCDDFFDDDDEDDDDDDBDDBDDDDDDDDDDDDDDD
@8YY
TGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGTCACTCTTCTGTGT
+
@@@FFFFFGHHHHJJJJJJJGHIIJIIIIGGIGGHJJJJJJJJJJGGGIIEHGHFFHHFFFF>CEDEEDDAB?CCCECDDDDDDD################
@8YZ
CTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGTCACTCTTGTCGG
+
CCCFFFFFHHHHHJJJJJJJJIIJJJJJGHGIJIJIJJGHJJJJJJIIJJIJJHHHHHFFFFDACEEEDDDDDACDDEDCCBDDDB&5)&2>CC@@#####
@8Z0
GCGAAGTGGCCACTGCTGCGGGAGCACAGACCCCACCGTGCCGGCATTCCTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGC
+
CCCFFFDFGHHHHIJIJJJJJJJJIJIIIIIIIJCHJJGIIJJHFDDEEEEEDDDDDDDDDDDDBDB@B8>CCCDD@BDCCEDECCDCDDD3@B?BBB<@<
@8Z1
GAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCC
+
B@CFDFFFHHGGHGGIGJIIJIIJJGGGHEGGIJGIGDGHIDEIGBHIIIFHHCEFFFFDBBDDDDDDDEECDDDEDDDDDDDD@DDDCDDDDBDDBBDBD
@8Z2
ATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGCGTCACTCTTGTCGGTGGA
+
@@@BDFFFGHFHHDHI>:CGGGEGHIIC*@FH>EAFFGGI9CFHGGIIIG@EHFHD>?D.;;@C>C:;A;?ACDD@ABD######################
@8Z3
GAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCC
+
@@@FD?DFHGHHGGG>DEDEIHEHJJ8F)@DGDGGIIIGGIGB7=:@F@EHFHGGFDFFDD@BD@C@C@:BCCDCAAAC5599@?<@>>@B?CB#######
@8Z4
CTGCCAGCCACCAGGTGGTTGGTTGGGGCTGTGCTCTCAGGAGCAGAGGTGTGTGCACAGGTAAGGGTCTGAGTGCCATCTGCTGGCACGGGGGTGCCCAC
+
@??BDDDDHHHGHIIGIJIIGIHIIHIJIJIDHIIIIEIJGEII=FEHG@@E5?CEHEEDF@@CCCEBCCDCC>@CC>@?CCCC::?CD9>3<B59@A?C@
@8Z5
CGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGTGTCACCATTCTGTGTCGGTGGGCGGAC
+
@@@DDDDFFFFDDGHFEB@EHI<DB:?FE>FE?GEHB4.BHIIIH9CFDG6CEHFHCAHE;@CECC>A?@?##############################
@8Z6
GAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCC
+
C@@FFFDFDHHDHIJIJJIIGEGIGIIJJJJJI<DGGIGIGIJIIGIEHGEHCFHFFFFDDBDDDDCCCDFDDCCCDDCDDBDD<ACCAC@DDBDA@@DBB
@8Z7
AGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCC
+
@<@?BDD?C<<??:+AF?AAGC;8@1:EEGEF@FFII<DB807C0AAAEECCC=A?;;83/398?:;A;B###############################
@8Z8
GTTTTCCTCCACGGCTTGCTCAGGGCTGCCAGACACTTTTCCTGGAGACACCATTTGGTTCTCAGAACTTCCTGGGCTCTGGGAAGAGCTTGAGCAGTCCA
+
@@@DDDADF??FB?1<C8@A@<EE@G@G;F>D?DDGIFFFFF4?F2=FFCFFFEC@@E6=?AEF?7@?@DDC>>>==???A>?9???5<ABB?:>@#####
@8Z9
AGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCC
+
CCCFFFFFHFHHHJJJJJJIJIJGIIJFIEHHFGHIJIGGHIJJJIJJJHHHHHHFFFDDDDDDDACDDEDCDCDDCDBDDDDBBDEDDDDC?CCDBB9BD
@8ZA
AGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCC
+
@BCFFFFFHHHHHJJJJJJJJJJJJIIJJJJIJJJIJIIJJJJJJJJGIHHHHHHFFFDDDDDDDDDDFFDDDDEDDDDDDDD?BDEDDDDCDDDDBBBDD
@8ZB
CGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGTGTCACTCTTGTCGGTGGACGTCACGGG
+
<@@FFFDAFDHHHIIHCBHIIGEFGGH@G@CGHIIGIA>8CA<@FGCCC;6=77?CACC=);@@>;ACBB###############################
@8ZC
GCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCT
+
CCCFFFFFDHGHHJDHGGIJJJEIGIIJJIIFIIJIHHBGE;DGFGGIHFHGCEFFFFDDDDDDDDDDFDDDDEDCCDDB>BBACCC:09>?:@9@DBDBD
@8ZD
GTCTGAGTGCCATCTGCTGGCACGGGGGTGCCCACACCCGCAGGGCAGCCCAGGGCTTCGCCAGGCAGACCCTGCAGGGGTGCTCCTCCGCAGGCTTCCTT
+
CCCFFFFDHHGGBHIGIJFHIIJJJJJJ7@HHHIIGHFFDEBABBDDDDDBDDDDBBACDDDDBDDDBDB8ADCDDDDBDD>BCDDDDDDD<BD@BCCDDC
@8ZE
TGAGGACTCAGGGTCATGGCCCTGCCAGCCACCAGGTGGTTGGTTGGGGCTGTGCTCTCAGGAGCAGAGGTGTGTGCACAGGTAAGGGTCTGAGTGCCATC
+
CCCFFFFFHHHHH@GIJIJJJJJJJJJJJJIJJIJJ?DHFGIIHGJJJJJIIGHHGHHFCFFFDD(>ABD;?@BBDDEDCCB>@CDDDACCDDDCDDDCDC
@8ZF
GCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCT
+
CCCFFFFFGHHGGJGIJJIJIIJJ>GHIIGJJBAGDHIJCHIGIJJIIAHHHHHFFFFDDD@BDDDDDDCDDDEDDDDDDDDBBDECDBDDBDCBDDDDD9
@8ZG
GCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCT
+
CCCFFFFFHFHHHIJJJJJJIIIJJJIJJJIJIJJIIIIDHIJJJIIJJFHHHHFFFFDDDDDDDDDCDDDDDEDACDBBDD<ACDDC<CCADCD<>5>@@
@8ZH
GCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCT
+
@CCFADFDHHHGHJJJJJBGIJJJJIGJJGIJIJIIJIJJIGIIIIDGJHHHGFFFFFDDD@DDACDFEDDDCDCCCBBBDD<ACCCDDDDDDD@<@BDD<
@8ZI
CTTCCTTAGGGATTGCACCAGGAGGCGAAGTGGCCACTGCTGCGGGAGCACAGACCCCACCGTGCCGGCATTCCTCCTCGGCTCCGTGCGAAGTCTCCGCT
+
BCCFFFFFHHGDDHIJJJJJJJJJGJGGIIHC<FHGIJJJJJJIJI/<BBBCEEB@BDDDBB<A;BBDDDDDDEDDDDDDDDDDDBDD>9&09?CCCCDDD
@8ZJ
GCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCT
+
@C@FFF:BFHHGHJJJFDHGHIIGEHGGIGIIHIIEHIFGCDFBHIIIIGHGHFEFDFDDDDDDCACDDDDCDEDC@B9<@B@ACCCCDD:8A:9>BBB9@
@8ZK
GTGCCCAGGTAAGGGTCTGAGTGCCATCTGCTGGCACGGGGGTGCCCACACCCGCAGGGCAGCCCAGGGCTTCGCCAGGCAGACCCTGCAGGGGTGCTCCT
+
@@@?DFBDHAFDFGIEFAFCHHIJIJI?F>EB3CFEGHEHIJ:?;>D;=B?BDDDDDDDBDB?<@BB?78889>BDB><B122<ABC?BCCDD>59?CAA3
@8ZL
TGTCACTCTTCTGTCTAAGGAATAGGAACTAAGGTTTTCCTCCGCGGCTTGCACAGGGCTGCCCGCCACTTTTCCTGGAGACACCATTTGGTTCTTAGAAC
+
<<@BDBDACDHFDEFBEEHEBFI+A@CHGG@CEFE4ECHHIGE)?0@A/;@D)...((5;8?A(,3;BB(:@@:ACCA<<>B39@A###############
@8ZM
TGGGGGTGCCCTTTTGCTGGTGGCGCCATCAGATACATCAAATTCTAGTTTTACAGGTCCGCTCCTCGAGGAGCTGGCCATTTGGCCTGCAGCCACTTCTT
+
@@@DDD@DFF9DHIII>C<E9:??FF:AGBFGAC<C=FHICA@AHGGH;;EE?E>?>7;?B'=>?CC;@B63??29<?BCACD>@:@@@?C?>88?:@>C:
@8ZN
CTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCC
+
CCCFFFFFHGGFHJIIIGHIJJJIJJIIIGIEDDHGIDIIJIHIIJJIJHHEHFBDBABBDDDDEEDDDDDDDDB@DDBB<CDCDDDDDCD>BBBDBDBBD
@8ZO
CTCGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCT
+
CCCFFFFFHFFHHGHGIFHIJJJIJIJJJIIJDIIGJIIIJIJJJICDHE@DDAACDDBBBDDDCDDDDDD?BBDDD>CCDDDCDDDD?ACDDD@CCD?C<
@8ZP
CTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCC
+
@@@BDDBDFDBD?EBBF3<)<@GEBGBFFEF9BFAGC9BF@BBFECA@CE?ECDDD<,9>BBB:BDB>5>A:>(;>9092<B3>>?3>?>@B#########
@8ZQ
CCGGCATTCCTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGT
+
CCCFFFFFHFHHHJJJIJIJJIFHAFH0?)9/?F0;@GHBC9@F==@@G==:BE7<B<6=?'8'3(,:AD;509@>>A@(+:@12<?A>>3@@>:<(:??#
@8ZR
CTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCC
+
CCCFFFFFHHHHHJJJJJJJJJIJJJJJJJJJJIJJJIJJJJJJJJJJJHHHHFFFDDDDDDCDEFDDDDEDDDDBDDDDDDEDDDDDDDDDDDDDDDDDD
@8ZS
GTTTTCCTCCACGGCTTGCTCAGGGCTGCCAGACACTTTTCCTGGAGACACCATTTGGTTCTCAGAACTTCCTGGGCTCTGGGAAGAGCTTGAGCAGTCCA
+
CCCFFFFFHHFHCDHIJGEIJCGGGIIIIIBD?DFHGIGIGGHGH@CCHGCGGGGGIJHHHFHHEFEFEFCCEC>=ACBDDCCBDDDBDDDDDDCDDCAA:
@8ZT
CTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCC
+
@CCFFFFFHHHHGJGHGIIIIIIIIJIJJJJJIIHJHGHJIJJJFIIIJHHHHFFFDDDDDDDDFEDDDDEDDCDDB9>?ACEDDDDDD@@@DDDDDDABB
@8ZU
TCTGTCTAAGGAATAGGAACTAAGGTTTTCCTCCACGGCTTGCTCAGGGCTGCCAGACACTTTTCCTGGAGACACCATTTGGTTCTCAGAACTTCCTGGGC
+
@@@FFFFFGHGHHIJIJGIIIEAHC<FHIHDHDCFF?FGBGGGFDAGGD7=01=F==CEHG>EH7A3@>BFF@@@?(;ACCCBB35>C>3:<>@CA:(9?@
@8ZV
CAGGAGGCGAAGTGGCCACTGCTGCGGGAGCACAGACCCCACCGTGCCGGCATTCCTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCT
+
@BCFFFFFHHHHHJHIJJJJJJJJJJJJJJJIJJGGIJJHGHFFFDDDDDBDDDDEDDDDDDDDDDD@?BDDDDDBDCDDBDBDDDCEEEDDDCDDD<BD<
@8ZW
CTCCTCCACCTCCTGCGGGGCCTTTTGCTGCCTCACTGCTGCTTTCCTCAAGGGAGGCTTGAGGCCGGACCTCTCTCCCAGTCTCCTTGGTGGGGGTGCCC
+
@?@D?DFFHGHFFIBHG6C:DDF>BDG88BDHFDC;;CG@GGHFBEHHD3@CC(;89;=='9@38<@D;@0(@39@>>C?#####################
@8ZX
GCCACTTCTTCCTGAGGACTCAGGGTCATGGCCCTGCCAGCCACCAGGTGGTTGGTTGGGGCTGTGCTCTCAGGAGCAGAGGTGTGTGCACAGGTAAGCGT
+
@@@DD>DDBHDF?E<EHEHGGIGGF222<FH<C=FGIBA<DECEGGCG*0-77;8FCCEHEEECA;>>@################################
@8ZY
CTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCC
+
;;?DBDDDF>FDCBG+CG=:?8AFGEGEBD)?DFEFDGEI@FF45;CEFE)=?BDDC?@??@BBBBB>AB>@AABB9@58?BD>>?BBBBBB99@>@>BB<
@8ZZ
CTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCC
+
CCCFFFFFHHHHHJIIJIJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJHHHHFFFDDDDDDDDEFDDDDEDDDDDDDD?ACDDDDDDDDCDDDBBDDDDD
@900
CTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCC
+
@C@DDDBDFBFHBBHG3A;FHBFGFHIFBGHEFHGFDHHHGGIG@CC@HAAEHFFFDDDDDCCADDC>@CDDDDDDDBD28AC:C@?C@ACDDDBBD>BBB
@901
CTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCC
+
?@<DD;=2AC?B?E@@BEHEGDGIGIIB<@FH3D@?BD6D<@FBHIIH9.==ABEECCB;?5@A@@>:>5;A@5=<BB><BA3:@@C@B############
@902
CTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCCACTGCACACACGACCTGTACATGATCATGCGGGAGCGCTGGCATGCCGCGCCCTCCC
+
<:=?DBBBDDDA+A3E@+38C:18CE1C:DDDDDC@DD;8ADD'5A@C<?=AD>D><33?<-;>BB>AAA5>A############################
@903
GGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGTGTCACTCTTGTCGGTGGGCGTCAAGGTAAGGACACGGC
+
@@?D;DEFHHHHGJIFHHGIIJEHGGJFCFGGCHGCGIJ3BGHIGGIJDGDGCHEGIJIIF@'85:C:>>(:>@C<55?######################
@904
CCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGTGTCACTCTTCCGTGTCGGGGGAAGTCACGGGA
+
???ABDDDHDHFFDHAFHGII??FBCACFDFDBG?FB8?DBAFHG@=)===AEEEIEH>;CEDEF:@B#################################
@905
CTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCC
+
CCCFFFFDHGGHHDIJJIJJIIJJJHGIJGIIJJIGGGJJIJJIJFGHIHHFHFFECDDDDDDDEFDDDDEDDCDDDD><ACDACBDDDDC@BBBDBDD?B
@906
CTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCC
+
CCCFFFFFHGHHHJJJJJIJJIJIJJJJJJJJJJJJIIIJJJJIJGIJJHGGHFFFDDDDDDDDEFDDDDEDDDDDDDD?BDEDDDDDDDDBDDDDDDDDD
@907
CTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCC
+
@CCFFDDFHGFDDHIJJJGGHHJIJEGHJBGEHIIGIEDHIBGBEG@EDEEFHFBBDDDDD>A>5>ACCCD@A:8>B><8AACDDDDCDCCDD<BDDDB@D
@908
CTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJIIIJFHEHFFFDDDDDDDDFFDDDDEDDDDDDDD?BDEDDDDDDDDDDDDDDDDDD
@909
CTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGTGGGGGTCACTTTTCTGTCTTAAGGATAGG
+
===A<A<AACB7ACAA81:@BAAA=AAB=;*=?3=>BB).)9>=4=>BAB<A(7=AA??>);>>@####################################
@90A
CGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGTCACTCTTCTGTGTCGGTGGACGTCA
+
CCCFFFFFHHHHHIJEHIIJJJJJJJIIJJIIJHIJIJJIJJJJIJJJJJJHGHHGHHHFDFFEEEEEDDDDB-<0-8>@C@A##################
@90B
CTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCC
+
@CCFADDFHHHHFIIIIIIII8FGGIIIGIGIFIIIIDGIDIIGIIIIIHHHHFFFCCBCCCCCEFCCCCECCC?<B<B8?CECA@CCCACBBB95<BB@?
@90C
CACAGGTAAGGGTCTGAGTGCCATCTGCTGGCACGGGGGTGCCCACACCCGCAGGGCAGCCCAGGGCTTCGCCAGGCAGACCCTGCAGGGGTGCTCCTCCG
+
?@@;DABABBHAAC@EHE<AFGAFGIHIIHGGEFDEBEHGECDEBEBCBC;>==@BBB;BBBBBBBBBBCBBB<@B@2<8?B<3(<<3+)0<@?3+>A?##
@90D
CTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCC
+
@@@FFDDDFHGHHICGGGIIGGIIJIHEGIDEFEHIJJJGAHHBGGIEBACCEFFE?DDDCDDDBDCDDCEDDCD@B@BDDDCCD?CDDCCB@BB.9>?B@
@90E
TAAGGGTCTGAGTGCCATCTGCTGGCACGGGGGTGCCCACACCCGCAGGGCAGCCCAGGGCTTCGCCAGGCAGACCCTGCAGGGGTGCTCCTCCGCAGGCT
+
CCCFFFDDFHHHHIJJJJJJJJJIGGHJJJJJJ;EHIHGHHFFFDDDBDDDDDD2?BD@BDABDDDD@DDDDDDDBDDDDDDD5>59?ACDCDD>BBDDB8
@90F
CTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCC
+
@@?DBDFBFHHHHIIIIIIIGDGGIID8GAHIIIIGH?CAH<FAEGCGDEEEHFFFCCDBC>CCDCDDDDDCCCBBDDD?8@::@?AAA:@9-<B><BDDD
@90G
CTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCC
+
CCCFFFFFHHHHHJJJJJIJJIIJJJJJJJIJJJIJGEIJJJJIIJJJIHEHHFFF:CDDDDDDDDDACDDDDCD>B@B<ACEDDBCABCC<BDBDB>BDB
@90H
CTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJIIJJJIJIGIJJJHHHHFFFDDDDDDDDEEDDDDEDDDDDDBB?BDEDDDDDDDDDDDBDDDDDD
@90I
CTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGGCACTCTTCTGTCTAAGGAATAGG
+
8?8=ADDDFADDFEFGI1CA@EGEFGFFEFEFIIFEBFIFFFFIFEI9DA@E?CEFFDD>BDDCCCECCBBB?@###########################
@90J
CTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCC
+
@CCFDDDDHHFHHIJGGIJJIIIIIEHIIGGICFFHIJGEGIJGGGIIJGHHHFFFDDDBDAACDCCCCDEDDD@DD<B<?CCCDDDCBD>BBBB<><<??
@90K
GCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGTCACTCTTCTGTGTCGGGGGGCGTCACGGGAAGGA
+
CCCFFFDFHHHHHJJJJGHIJJJJGJJIJIIIJJJJJJJJJDFHIIJDIJHBGIIIJJJJJHDD#####################################
@90L
CTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCC
+
??<BB:BB3C8BDDDA?<C61)2A1C)?D)BD>BACCCDD<@A@@;@>C>)7659?<<;??;>:BBAA3>AA3:8>?>928:AAA################
@90M
CTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCC
+
CCCFFFFFHHHHHJJIJJJJJFHIJJIJJIJJGHIJJGIJJJIIJJJJIHHHHFFFDDDDDDDDFFDDDDEDDDDDDDDDDDEDDDDDDDDDDDDDDDDDD
@90N
GGCGAAGTGGCCACTGCTGCGGGAGCACAGACCCCACCGTGCCGGCATTCCTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGGG
+
;@@DDDABDFDHFEHGE<FEDHH8GD=BDGGGHIIHIEG6CAEEH<>CCC;@@>?=?BB@@B@2<08>7>034>C90)5<::4:4(4@@C###########
@90O
CTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGGGACTCTTCTT
+
?@CFDDFFHHGHHJJJHGIJJJG@FBEHEHDGDGIBHGIJIBDA;FEG6@@GGEHDEFHFEFFFD6>CACCCCABCDCADDCCDDDD##############
@90P
CTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCC
+
C@CFFFFFFFDDHIIIGIGIEEHGIIIIIGHIDFHIJFGGGIJEHJGIIHEFHFFBAA>BDCCDEDDDDDEDDD@DB@B8ACEDDDDDDDDBBDDBDDDBB
@90Q
CCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGTCACTCTTCTGTGTCGGTGGACGTC
+
CCCFFFFFHHGHGJGGGHGIJEHHIIGBGIIIIIGIGIJGGIIHGIIJIGECHEHEHFFFFFEEEECCCDDDDD&0002::@@A#################
@90R
CTCGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGGCTTCTAGGGTCT
+
@@@DDDDDHHFBD@E:@G>D@G:DFHIG<BDG4B@8?4B0;C@EF/(-:=?69,5;;A3;==@3>?A>A@?<1<9:>4@C>AA9@:??&05?3:+:@A###
@90S
CTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCC
+
CCCFFFFFHHHHHJJJJJJIJIJJJJJJJJJJJJJJJJJJJJJJJJJJJGHFHFFFDDDDDDDDEFDDDDEDDDDDDBD@BDDDDDCDBDDBDDDDDDDDD
@90T
GGTAAGGGCCTGAGTGCCATCTGCTGGCACGGGGGTGCCCACACCCGCAGGGCAGCCCAGGGCTTCGCCAGGCAGACCCTGCAGGGGTGCTCCTCCGCAGG
+
@@@DDDDD+:C:C@AEEFIEIECBD3A@@F<DFF>@EEFFDBDDC>@BB8;@B8-8?B?@8;@(235>B@BBBBB0<1<?B@@?890&08@>A??BBBB<<
@90U
CTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCC
+
@CCFFFFFHHHHHJJJJIJIJIJJJJJIJJJJIJJJIGIJIJJJJJJJJHHHHFFFDDDDDDDDFEDDDDEDDDDDDDD@BDEDDDDDDCDDDDBDDDDDD
@90V
CTCTCAGGAGCAGAGGTGTGTGCACAGGTAAGGGTCTGAGTGCCATCTGCTGGCACGGGGGTGCCCACACCCGCAGGGCAGCCCAGGGCTTCGCCAGGCAG
+
@@@FFDDEDFHFFIIICECAHGHCDEHFGCHGGIHGHGE@DFGGHIIIIIGGIIIIEBB@>3=<<?C?BD@B>BDD@B7<>B<@BDBD?A@D@9<@<BB<<
@90W
CTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCC
+
CCCFFFFFHHHHHJJJJJJJJIJJJJJJJIJJJJJJIJJJJJJIIJJJJHHHHFFFDDDDDDDDEFDDDDEDDDDDDBD@BDEDDDDDDDDDDDDDDDDDD
@90X
CGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGTCACTCTTCTGTGTCGGTGGACGTCA
+
CCCFFFFFHGHHHJJHJJJJJJJJJJFGIIJJJHJJIJIIIJIJJIJJJJIHFHHHHHHFFFFEEEEEDDDDD############################
@90Y
CTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCC
+
??@=D>;DHHFHHEDC;CDF18CFE??FHHIG@DFC9)7B;@F-4;77@EEE???DCC>B=CAACCC@>ADCCC;5<>B8<C>A:8?:8A###########
@90Z
CAGATACATCAAATTCTAGTTTTACAGGTCCGCTCCTCGAGGAGCTGGCCATTTGGCCTGCAGCCACTTCTTCCTGAGGACTCAGGGTCATGGCCCTGCCA
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJIJJJJIJJJJJJJJJGHIJIIJIJJJJJJJJJIHGHHHFFFFFEEEEEEEDDDDDDDDDDCBCDDBDDDDDDD
@910
CAGGGCTTCGCCAGGCAGACCCTGCAGGGGTGCTCCTCCGCAGGCTTCCTTAGGGATTGCACCAGGAGGCGAAGTGGCCACTGCTGCGGGAGCACAGACCC
+
CCCFFFFFHHHHHJJIIJIJJJIJIJFFH0??DBFGIJJIIJJJHHHHHFFFFFFEEEEECDDDDDDDDDDDDDBDDDBDDDDDDDDDD>BBBABA?9<BD
@911
CTGAGTGCCATCTGCTGGCACGGGGGTGCCCACACCCGCAGGGCAGCCCAGGGCTTCGCCAGGCAGACCCTGCAGGGGTGCTCCTCCGCAGGCTTCCTTAG
+
@CCDFDDFHHHHGGGG<BFHIIIE@D7AGIIEGDEHHHF<ABD?;=<9@BA<@8?BDDD<BBA?BDBBADDDD?CA>B59?:>@CCD<>999BACDC>C>A
@912
TGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGTGTCACTCTTCTGTGTCGGGGGGCGTCACGGTAAGG
+
@@@FFDFFHFHHHJJJJEHGIIIFIIGECGGCGEGGIJJIJIFFHIJJJIEGHHIIEIJIJHFB?)5&(+:>@@CAC>@######################
@913
CTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCC
+
CCCFFFFFHHHHHIJJJJJJJJJJJJJIJJIJIIJJEGIJJJJDIIGIJGEFHFDDDDDDDCDDEDDDDDDDDCDDD@B?BCECDBDCBCDDDB>BDBDDD
@914
CTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGTCACTC
+
CCCFFFFFHGGHHJJJJJJJJIJJJJJJFHHGIIJIIIJJJJJJGE@GHIIHGHHFFFFFFEEEEDCCDDAADDDDDDDDDDDDEDDDDDDD#########
@915
CTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCC
+
???D?D:+CDDDDEE+2??1)<C@D@EDI:BDC?D=D9D=A6;5@A@>ACC?=??D@@???AA>>B;AAA>A>>;>>3>(2:::A<?##############
@916
GTGTCACTCTTCTGTCTAAGGAATAGGAACTAAGGTTTTCCTCCACGGCTTGCTCAGGGCTGCCAGACACTTTTCCTGGAGACACCATTTGGTTCTCAGAA
+
CCCFFFFFHHHHHJJJJJJJJJJJJIJIJJJJJJJHIJJIJJJIDHHHIJHGGIGEDHJGHIGHEHEHFFFFFF@CA@CBD?@CDD9>CD>A<A@CCCCDC
@917
CTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGTCACTCTTCTG
+
CCCFFFDFHHGHHIIIIIIGHJIFEHHG>GD@FHIIHGIIJEHCHIFIIIEHIHHFFHHFE@@DD2>ACCDDDCDDCCDDDACBBDDD#############
@918
GGCGAAGTGGCCACTGCTGCGGGAGCACAGACCCCACCGTGCCGGCATTCCTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTG
+
CCCFFFFFHHHHHJJJJJJJJJJIJDIGIIJIJJIIIIJGIIIHHFDDECDCDDDDDDDDDDD@@;5>5>(9@CD@>>@B::>@@:@C:@CA@@8<<BBA7
@919
CTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCC
+
CCCFFFFFHHGHGJJIIGII8GIGHGHJIHJDIJJIIGHIIJJGIJJGIHHHGDFBCD>BDDCCDDCDCDDDDC@BD3>??A@CCDCCBD(9><<99<BDB
@91A
CTTCAAGCTGCTGATGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCAGCGCCCTCCC
+
@@CFFFFFA?FABHGEEH>GIIIIIGBGGFFFBDG9DFCGEDHIGJ<)@>>E>?D'9>B6=>CDDDCCDDEDD############################
@91B
CCGGGATTCCTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGT
+
:=+:B8DDBBHHFHII@FE6GHICAFGGBDFB<?D6FGGEC@AEDDCACE75:BDE7=A?8?B@??>>CC35;9?C49>CC388(8>:@CCCC:>?CCB##
@91C
CTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCC
+
CCCFFFFFHGHHHJJJJJJJJIJIJIJIJFGDEHHIGJJFIJJIJIJJJHHFHFEFDDDDDDDDEFDDDDEDDDDDD@DDDDC>ABDCBDDD@B<<@DDDB
@91D
CTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCC
+
CCCFFFFFHHHHFGHIIIJJIJJIIJIIIJJIJJGGIJICHHIBHJJJIGHHHFFFDDDDDCDDDDDDDDDDDD@@BDB2<CDDDDDDDDC>>@BBDDDD?
@91E
CTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCC
+
CCCFFFFFGHHHGHG2AEHII>FHJIJJJIJJJJJJIFIIGJJJGIIJJHHFHFFFDDDDDDDDDDCDDDEDDCDDBDB?ACDDCDDCBDDBBBDDDDDDD
@91F
CTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCC
+
@CCFFFDEHHHHGBGIIJFIJJJJJJIFIGGJIJIGAHGHBFHIGIIIIHH9EFEDDDDBDCDDDDDDDDEDCCBBDDD<<CCCDDDDDCCDDDDD>>BDD
@91G
CTTCAAGCTGCTGAAGGAGGGCCCCCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCC
+
CC@FFFFFHHHHHJJEHIJGJIJ)@EHIGIJJJJAFHGIJBHIG/?DDD3?CADDDDDDDDD3@CDDCC@CCCCDDBBB@BCDDDDDDAACDDB<@<BD<B
@91H
TTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGTCCCTCTTCTTT
+
@@CFDFFFGHFHHJJJIJHIJFHDHHIDH?BFHIJEIJGI>GHGIIGIJJGHHFHHGHHFFFFD@A@@CCCCC<?C?CD@CCDDDDD##############
@91I
GCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGG
+
BB@FDAADHHHHHJJIJIJJJGIIIJG?GHIIIJEAG>G>AH;FHIIJHEEEFFCFCACDABBDDCCCCDDC?ACDB<ACAAC:@CB?CCDDDDD@#####
@91J
CACACCCGCAGGGCAGCCCAGGGCTTCGCCAGGCAGACCCTGCAGGGGTGCTCCTCCGCAGGCTTCCTTAGGGATTGCACCAGGAGGCGACGTGGCCACTG
+
@@@DFFFDFHH>H;EFHHIDFHGIHIH@FFDGDGGECEHH@EID;=:'987>>C>=A?BDBDDDDCDCDACC8?<>(:@CDB?@B@>B>5&)0<@@ACB>4
@91K
CCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGTGTCACTCTTCTCTGTCGGGGGGCGTCACGGTAAGGACACGGTCCC
+
@@?DF?DDBBFHFIIIGAEGIJIJHHGEDHHI:CFHGJJ*?DFHIFGHCHCEGHA',3:5:@C3@####################################
@91L
CGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGGCACTCTTCTTTGTCGGTGGACGGCACCGGAA
+
CCCFFFFFHHHHHIJJJJJIIIIJJJJHIJIJJGIJJGHI>GIIFGHIJIIIIJHGIHGGHGFFDDD##################################
@91M
CTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCC
+
@@BFFFFFHDHHHGIHHGIJIIJIIIIJJHJIJJJIJBHHJJJJJJFIJGHEHFFFDDDDDDDDFFDDDDEDDCDDDDDBBCDCDDDDDDDDDDBBBDBBD
@91N
CTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCC
+
CCCFFFDFHGHFHJJJJJJJJGGGIIIJIIIIJIHIGIGGGIIJJJJIGHHHHDFFDDDDDDDDEFDDDDEDD@B@D@B?BCEDDBDDDD>@<BB<<B<?B
@91O
CTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCC
+
CCCFFFFFHHGGHHGGJIJJJFHIIIIIGDHIBEHIIIJJJHBHIGGIIGHEHEFFDCDDDDDDEEDDDDDDDD;BDDD<?A@CA<ACBD3<BB<BD>?8@
@91P
CTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCC
+
CCCFFFFFHHHGHIGGIIJIJJIBHHI0CGIHIIGGGIHIJJJGGIIIIEHGHFFFDDDDDDACDEDDDDEDDCDD@5928@DDCBDDBDDBBB<@>>BD8
@91Q
CTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCC
+
CC@FFFFFGHHHGEHJI>GBFIIIIIJDH<DHGGGIIFHHIIIJIIJJJHHHGFFFACD@CCCDDED(>CDCCCBBB5@<8ACAABCDBD@><@BBDDDDB
@91R
CTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCC
+
CCCFFDDFHHHGGIIHIIIGIJJGGJIJJHJIIIJJGIJIDEIJJGIIJFHFHFFDBCBDDCDCCDDDDDEDDDDDDDD??>ACDDCDDDCDDDDDDBDDD
@91S
CGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGTGTCCCTCTTCTTTGTCGGGGGGCGGCA
+
CCCFFFFFFDHHHGIFHGIIJJGIJIEGIJJJFDHIJIIIJJJJJFIIGIGDAEHHEFEEDFDCCCEE?@BD#############################
@91T
CCTCGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTC
+
CC@FFFFDHHADF:DD@EFEDFGD<GEHCHGHG*B????<AHIIBE@@CHDBAC@CCCCBBBBBC@?>:>CBBB?9:@:@C@A@CCCCC13(:44(::?33
@91U
CTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCC
+
@CCFFAFDHHHHGIJIJI9DH@FF=C@FG>F9D>F9DH@FHHHEHHIIJHGHHBF8>BDBDC@CDDDCDDEDDCB<B-<<ACDC@BCDBCA9>@DDB.A##
@91V
CCGCAGGCTTCCTTAGGGATTGCACCAGGAGGCGAAGTGGCCACTGCTGCGGGAGCACAGACCCCACCGTGCCGGCATTCCTCCTCGGCTCCGTGCGGAGT
+
CCCFFFF>FHHHHGIIIIHIGIIBHIIIIIGG@GGBGCH>FHGIIGGIIHHFFCBBCC(9>BB<<<>BBABBBCCB>>C>C:CCCCBBCBBCBA<>BB###
@91W
CTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCC
+
CCCFFDFFHHHHGJBHIIIJJJJIJJJJJJJJJJGIEIJJJJJJJJJJIHHGHFFFDDDDD>CDDEDDDDEDD>=<BDB?ACDCCD<CDDA@BDB@D@DDD
@91X
CTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGAGGGAGTGCTGGCATGCCGCGCCCTCCC
+
=>=A;AAACBCBCBBCBA+?C)?A?AAAAAABBBABBBA=AAAAAABBBAAA.5=@6====??????:>??9(,5;<=;;;????<;?=??===;=;;==8
@91Y
CTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCC
+
CCCFFFFFHHHHHJIIJJIIJJIIJJIJJIJJIIJJJIJJGIHGHJIJJHHHHFFFDDDDDCDDDFD>CDDDDDD@DDD<BDEDDDDDDDCBDDDDDDDDB
@91Z
CTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGGCCCTCTTCTGTGTTGGGGGGGGG
+
CCCFFFFFHHHHGJJIICGHIJJJJJJIGGGIIIJDCGGGCHGIIEIIIJHIAEHHHFDDFF@CEE@CCDDDDDD##########################
@920
CTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCC
+
CCCFFFFFGHHHHJJJJJJJJJJIJJJJJJJJIJJJIJJJIJIGIJJJJHHHHFFFADDDDDDDEFDDDDEDDDDDDDD?ADEDDDCDDDDDBDDDDBDDD
@921
CTCAGGAGCAGAGGTGTGTGCACAGGTAAGGGTCTGAGTGCCATCTGCTGGCACGGGGGTGCCCACACCCGCAGGGCAGCCCAGGGCTTCGCCAGGCAGAC
+
CCCFFFFFHHHHHJEGHHIIJGIIJJEHIJJJGGIJGIGHIJJGIJJJJHHJJJJJJJD?BBDDDDDDDDDDDDDDDDDDDDDBBDBADDDDDDDBB<BBB
@922
CACTCTTCTGTCTAAGGAATAGGAACTAAGGTTTTCCTCCACGGCTTGCTCAGGGCTGCCAGACACTTTTCCTGGAGACACCATTTGGTTCTCAGAACTTC
+
CCCFFFFFHHHHHJIJJJJJJJJJJJJJJJJHIJJJJJJJIHIJIJJBHEFEGIJGGHGICEAEHHGFFFCFC@CAECD=?B;@CDACABCC@:@ACCCD@
@923
GTAAGGGTCTGAGTGCCATCTGCTGGCACGGGGGTGCCCACACCCGCAGGGCCGCCCAGGGCTTCGCCAGGCAGACCCTGCAGGGGTGCTCCTCCGCACGC
+
?@<BADDA?DHHFCFDHIGGD4CCGIIIGEHGBH45@>AEHEE=ACC??=B8(07078<?BB(8<;@7B9B?BBB<A<9A?3389@)0<(:>C9?<@####
@924
CCGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGGTCCGCTTCTGTG
+
CCCFFFFFHHHAHEHIEEHGIEHEHIGIFGGIIIE<F;FB=;=;8;;CAHHHHHFHFFCFFDDACCCDD;>CDCDCDDC@CBDDDD###############
@925
TTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCA
+
B@@FFFFFHHHHGJJIJIJJJIIJJIJIIIJIIIJJJJIJIJJJJIJJJHHHHFF<ADDDDCD(,,5@CDDDDDDDDD??ACDDDDCDDDDBDDDDDBBDC
@926
TCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAG
+
@CCDDFDFGHDBF@CFG<CFHGGEDE>FHHIIIIEAGIEHHG>EEHIIGHHHDBDDDDDC@CADDCCDEDD@B9<>BBBCDDCDDC?ACBBBBBDD?BBD@
@927
TCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAG
+
CCCFFFFFHHHGHJJJJJJIJJJJJIJIJJJJJJIJJJJJJJJJJJJIHHHHFFFDDDDDDDDEDDCDEDDDDDDDDBDDEDDDDDDDDDDDDDDDDDDDC
@928
CTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGTGTCACTCTTCTGTGTCGGTGGACGTCACGGGAAGGACACGGGCCAGGTCCTCCAC
+
CCCFFFFFHHHHHJJJJJJJJJHHIJJJIJJJGHJJJJIJJJJJH,936;;@CDDCCCCCA@=B3?@249058?5<&09<@223259&092<?(+::>?3<
@929
TCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAG
+
?@?DDDFFHHGHGIGGGII<EHCGHIGHIIAFGIGHIEFHIIIIIHGGHHCC<>DCCBDCC@C@ADDDEDDC8>B3<+8:>AC?C@ACCD<>9<>9<@DCA
@92A
TCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAG
+
BCCFDFFFHHHHGJIJIIJJJ=FHGHGIJJJBHIIJJJFIIGIJJIIJHDHHFFFDDDDDDDFEDDDDEDDDBDDDBBBDCCCDCCDDDDDBBBDBDDBC>
@92B
TCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAG
+
CCCFFFFFHHHHHJJIJJJIJIJIJIJIJJFIIJGIJJIIJIIJJJJIHHHHFFFDDDDDDDEFDDDDEDDDDDDDD?BCDDDDDDDDDDDDBBDDDDDDC
@92C
CAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGA
+
CC@FDDFFFHGHGJGHIJIFHCEHGIGFEHIFIGCGGGGGEGHI@@EA3=A<BBABDD>@ACDDDCDE:>:?@;-58?CDCDBDCBCDB@BD>@>A?B?>A
@92D
CAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGA
+
CCCFFFFFHHHHHGIJIIIJJJJJJIIJJJJJIGHIJJJJJIJIIJIIEEHHFFDDDDDDDEDDDDDEDDC@DBBDBDDDDCBDDBCDBBDDBDDDDDDC?
@92E
CGGCTCCGTGCGGAGTCTCCGCTTTGTCCTGGCACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGTGTCACGCCTCTCGCTGCGGGCTACGAA
+
@@?DDAD:<AAF:8@<C>F9CDEEF>B*00?F2/??8*8)/8/8.))=(;6=AECA>3)....7;;AAC@/;B5@BA########################
@92F
AAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAG
+
@CCFFFFFHHH+2:EHIJJJJIIJIIJJJJGGGHIGIGHJJJJJIIJJHHHFFCDDDCDDEFDDDDEDCDD@DDD?ACDDDBCDDD@BDDDDDDDBDC(8?
@92G
CTTGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGTGTCACTCTTCTGTGTCGGTGGGCGT
+
CCCFFFFFHHFHHJJIJIJIJJIIJJJIHGIIIIIHIJIJGGIICGIIJIEH=ACHHHHFFFDFEEDEEEDDDDD)55:::@@:A>@3:@###########
@92H
AGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGAACATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGG
+
@@@FFFFFHGHGGJJJJJIJJGIJIJIIJIJJEIJIIJIJIJJJJJJJHHFFDAAECDDEFDD5:@CCDD:BB;<BDDDDBDDDD>>@DDDDBDDDDD?BB
@92I
TTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGTCACTCTTCTGT
+
CCCFFFFFHHHHHJJDGIJJJIHHGIJJIIJIIIGHJJJJJJJIJJIIJDHHGHGHHHHEFFED@AEEDDDDDDCCCCECDDDDDD5&0)&2>C>:@>>:4
@92J
GCCATTTGGCCTGCAGCCACTTCTTCCTGAGGACTCAGGGTCATGGCCCTGACAGCCACCAGGTGGTTGGTTGGGGCTGTGCTCTCAGGAGCAGAGGTGTG
+
=8?BBBDDF+CFHBHCHEHGGGHHHEFHIGEAEEBD@1?@BDAF@*0?FHD)?FGIFHA=CH@@=;:1;?B;5988?=B9:5>@>::((:8AB########
@92K
GCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGC
+
CCCFFFFFHHHHGIJIIIJJIJJJHIIJGJJIJJJJJBGGIIIJJGHHHHFFDDEEDDEDDDDDEDDDDDDDDBDCDDDDDDDDCBDDDDBBBDDDDB8?@
@92L
CTTCCTTAGGGATTGCACCAGGAGGCGAAGTGGCCACTGCTGCGGGAGCACATACCCCACCGTGCCGGCATTCCTCCTCGGCTCCGTGCGGAGTCTCCGCT
+
CCCFFFFFGHF+2ACFHIEIJJJIDHIGDDGEIJIGIJJIGIIJJJHFFFEE(.;?CB?DDDDBDBD@BDDCDEDCDDD>BBDDDDB@BB<B@2>@>C<@B
@92M
TGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGTCACTCTTCTGTGTCGGTGGACGTCACGGTAAGGACACGGTCCAGGTCCTCCACC
+
CCCFFFFFHHHHHJJJJJJJJCFHIIJIJJJFHIIJJGIJIJJH/5)02>999@::::>@@7<&8>2>509<@;B2?@>C>8380<+89>:C+4>:@C9<B
@92N
CTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGGTACCT
+
@@@FDFDFHHDHHIHIJIGGHIIHJGFHFF@GHFEDHGGHGHIIGICGHDGHCHEEFFFFDCCCC@ACBD?>ACCCCDDBCCCCCC>CB@BD#########
@92O
CTCGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCT
+
@CCFFFFFHFFHGIJEHCGHIJGGBHIGI@FICIIGIDH@GGGEH66;AE=BDACDDC8?;@BCCCCCCDD<?BDCCDDC@ACCDCDD2>ACCCCCDD3>9
@92P
GTGCCATCTGCTGGCACGGGGGTGCCCACACCCGCAGGGCAGCCCAGGGCTTCGCCAGGCAGACCCCGCATCGGCGCTCCTCCGCAGGCTTCCTTTCTGAG
+
:??;AB?DFF?F+2<2<E1@<0?A688@5C@@@84'999=5>?(5998;?BB30-025?@#########################################
@92Q
CTCGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGGCTTCTAGGGTCT
+
@@@DDDDDFHHHD>BA:??C9D@<:@FFF4?B*BD<DEG'7;FAFE=1==?BBA>A>@@B@@BC553;ACB1??9::(+:@:@3::?7&&)23@A:@<A?<
@92R
GCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCA
+
CCCFFFFFHDHHHJIJJJJJJJJJJIJJJJJJIJJJJJJIIJJJIJHEDFAEEEEEEDDDDEDDDDDDDDBBDEDDDDDDDDDDDDDDDDDDDDDDDBDDD
@92S
GCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCA
+
C@CFFFFFHHFFHGGHIIJGGIGEHGIEDGHIIGDHGGCGHHIJIGFHFDBCEDACBCDCCDCCCBDB;B8<@CCCDDDDCD<5<@9@DD@@CA?BB<?BD
@92T
GCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCA
+
C@CFFFFFDFFFDGHJGGIJJJIGHHIEGIGIFIGHIJJIGJIIJJEADFBECECEDDDDDECCCDDBDD2<A>CCDDDBDDDD@BDBBDDDDDD?@@@BB
@92U
GCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCA
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJIJJJJJJJJJJJJIJJJJJHHFFDEEEEEFDDDDEDDDDDDDDBBDEDDDDDDDDDDDDDDDDDDDCDDDDDD<
@92V
GCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCA
+
@C@DDFDDBDDDFDHGGHIIGCCIHGHEIIGIJJAGFHII@CGGHIFEFFCEEEDD@>@CCEDCCB@B5;2<@C@C?CC@CC@9><<>BBDD<C88?BDB@
@92W
CTCGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCT
+
@@@DFFFFHHHHGJJJJGEIJJJJJJJJJJIJHIIIGJJJJJGIJJGIHHFFDDDDDDDDDDDCCCCCDDDBDDCDDDDDDDDCDDDDBDDDDDDDDDDDD
@92X
CTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCAC
+
CCCFFFFFHHHHHJJJJJJJJJGIIJJIJIIJJJIJIJJJJJJJIHHHFFCEEEFFDDDDEDDCDDDDDDDDEDDDDDDDDBDDBDBDDDDDDDDDDDDDD
@92Y
CTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGGGGCGGGAGGCACTCTTCCGTGCCGGGGGGCGG
+
+???DBD?B8221@<@E1:1?9@DD000?BB?D?D29(=)88@@;AD9AC55(.=777@AD@7(6;@A(2>;>?###########################
@92Z
CTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCAC
+
==1<AAA+A0A8+?ACA)0?5?=ABBBBAB0:0=AA7==A>AAAAA:<6/6.;;@@B?B>?########################################
@930
CTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCAAACACGACCTGTACATGATCATGCGGGAGAGCTGGCATGCCGCGCCCTCCCAGAGGCCCAC
+
@@CFAAD>FADADFBFGGGBGEGGFCDG7F:FH6AGG9@F;@;DEB6<?<?@>;>;6>A3@C@C;:/80&+23?3<?><ACDD>@################
@931
GTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGTCCCTCTTCTGTT
+
@;?DBDDDH?FDHIGEIIGGGHIGIB<@??@BCHIIBGGBBFHGAGAACHGGGHFFHFEEEDE;ACCCCC@CBCCCADC>C7?@B################
@932
CCACCGTGCCGGCATTCCTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTTGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCT
+
CCCFFFFFHHGFDIIIHIIGIJIJJJIHJJ?FAAGABDC7;C8=/=?9?;6>>>ACE@@AC>CC@?9?@DD@>+3:@C>0&0<>>?>>:@@18?>>CCCC3
@933
CAGGGCTTCGCCAGGCAGACCCTGCAGGGGTGCTCCTCCGCAGGCTTCCTTAGGGATTGCACCAGGAGGCGAAGTGGCCACTGCTGCGGGAGCACAGACCC
+
@@@FFFFFHHHHHJIJIIJJJJIIJJGJGHFGGIIJIIJIJJJJHHHHHFEEFFFEEEEEDDDDDDDDDDDDDD@CCD?CDDDDDDDDDDDDDDDDCCDAB
@934
TGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACC
+
@@CFFDFFGHHGHJJBHIG;FHHCHHJJGIIIEBFGEIGJGHHJIFHFFFCCEDEECD>:@CD@=?@DBDDEDDDCDBDADDDDBBDDDDCA8888?BBB>
@935
TGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAAGCCCACC
+
CCCFFFFFHHGHHJJJIJJIJJJIJIJJJJJJ:AHIJIIJJJJIIHHFFFEEEEEEDDDEDD@B?BBD@ACEDDDDDDDDDDDDDDDDDDDDA(39AD?B>
@936
GAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCT
+
CCCFFFFFHHHHHJJJJIJJJJJJJJJJIJJJJJJJIJJJJJJJHHFFFFEEEFEEEEEDDDDDDDBDDDEDDDDDDDDDDDDDDDDDDDDDDDBDDDDDD
@937
GAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCT
+
7??DDDDDHF?CFEGIIEHFFF>GIIIIHFGGIG@EH@DDHHIDFHEB@D>CACECCEECCCBBBB7<ACDDCBCCDCCBBD5<<0?BBC@?<<<????B<
@938
CTAGGGTCTCAGAGGCGGGTGACACTCTTCTGTCTAAGGAATAGGAACTAAGGTTTTCCTCCACGGCTTGCTCAGGGCTGCCAGACACTTTTCCTGGAGAC
+
???DDDDDDDEDDIIIII)(7(=B==C=C7;@@CEADIC7?9=3@;@@AA>AA;AA?3>AAA#######################################
@939
AAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTT
+
?BBFFFFFHHHHHJJJIJJJJJJJJJJIIJJIJJJJIHJJJJJIHHFFFFFEEEEEEEDDDDDDDDBDDEDCDDDDDDDDDDDDDDDDC@BBD?BDDDDD>
@93A
AAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTT
+
<@@FFFFFHHHHHJJIJIJJJJJIIJJJJJGIIIJI@FGIIJIIHHFFFFEFDECDEEDDDDDDBB8<CDDDD9ABDDBDDDDDDDBD<C8<@?BDDDDDC
@93B
CCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGTGGCACTCT
+
@@CDDFFFHHHHHJJJJJJIJJJJJIGIIFGIDFFGHIFGHIJHJHGIJJGEEHHFFFFFFE<CEACDBACDCDDCDCBCDDDED@CDDBD##########
@93C
ATCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGTCACTCCTGTCGGTGGACGTCACG
+
<@@FDFFFHG?FFHGGIAGGBFGHIIJJ?FCHIJIGGBCFGH>FHIIIGG@EC>CHDFDECFAACCDECCDBB@###########################
@93D
AGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTC
+
@@@DFFFFHHFHDGHJGGIGFHFHIIJIIGIHHHAFHGGGGGEEHFF@DFBACEEECCEDBBB;><?CDCC?ADDDC@BDDDDBDDDDDB8??@DB@9B@C
@93E
AGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTC
+
@@@FFFFFHGHHFGHAFGGHIIGGGIGGGGIIJIFGGGIIGGEEEFEFFFFFDCCCDEDDDDDDDB?CDDDBCCDADDDDBDDDDDDDCBABD@BDDDDDC
@93F
AGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATAATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTC
+
@<?DFFFFHHHHAGH>GIGIHHGCFHAHHGHH>FHFD>FGIIGEHDE@BEFE(.6;ACCCBB?=B8?AACCDC@BD@BB@DB95A@@CC<?BD@8?BD?C>
@93G
GGGGATTGCACCAGGAGGCGAAGTGGCCACTGCTGCGGGAGCACAGACCCCACCGTGCCGGCATTCCTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGCATT
+
@B@?DDFFGHHGGHGEHIJJIJJJJJJJGIHGGHFIIHG8AHHFFFDECC?BDDDDDDDDDBDDDCDCDCDDDBBBDBBAB59BB7<CCDD@DDBDDDDCD
@93H
CCGGCATTCCTNCTCGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGT
+
@@@DDDDDHHH#2AFHIIIII<?EBGF6@?D8BGFGGGICEHIGIIIHGIF8ABBEAA==@>?8=8?CAABBB@B@((::4:<(21?3>A>@C3>9AAB02
@93I
AGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTC
+
?<@BDDD:CFHHDHH<BGEFEGFHGI@FGAFBG>FHIGACHIIHFFFFFFFFEECEECCC@@6=>@BCEDCDDAACA@99@B@B?@<CCDDD<8?@BBBC?
@93J
GCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJIJJJJJJJIHIIHJIIDHGIEIHHHFFCFFEEEDEDDDDDCDDDDCDDDDDACDDDDDCDDDDDDEDCDBDDDB0
@93K
CGGGAGGCGAAGTGGCCACTGCTGCGGGAGCACAGACCCCACCGTGCCGGCATTCCTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCT
+
BBCFFFFFHHHGHJJJJJJJGJJJIJJJHJIIIJEIJHHHFFFDDDDDDDBBDDDEDDDDDBDDDDDD?BDBD9@?CCCDDDDDDDC:@DDCDCDDC<@B<
@93L
CTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGGCACTCCTCTTTGGTGGGGGGCGG
+
@<?BDDDDF?:ADGI<@CGEGHDC:?FG<B<<DHE2B=FGCHA@9FEGHI@D?E>CEEBDEE;ACCDCCCBBBBB##########################
@93M
TACCGTGCCGGCATTCCTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTG
+
@@CFBDDFHHHHHEHJIJJIIJJDGIIJIGIBGH6F;FHGIB<<=DD@7;?@CEEEEC;@B@BB29?B&00;2>@::599@8(:<CA3:@<<89+(>ACC3
@93N
CTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTGGGGCCTCGGAGCCGGGTGTACCTCTTTCTGGTCGGGGGAGGC
+
@C@FFFFDFFDDHIJEIGGGJJJGIJJ>DHGIGHIHGJIJGGHGIIGCHJGD?EHFEF);@########################################
@93O
GCGGGAGCACAGACCCCACCGTGCCGGCATTCCTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJIJJJJJJJJJJJIIJIJHECEEAD?@8?CDDDDDDDDCDEEDEDCDDDDBDDDDBBDB@B<B+>ACCDDDDDDC?
@93P
CTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGTGGCCCCCTTCTGCTTCGGTGGGCGT
+
@@@ADDBDFF?FF@E6C:CGEG0?DGI<?)9DBA@BFFF@8.@F)8@C@C5C6?A;>3@D@BD@BCE##################################
@93Q
AGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAG
+
<@@DDFDFDHHHAHGIIIEEGG=GGDFHIGEEIBBFEFGHIIIIGHGHEHEEFFFFFCCB=B5?ADC@BCC?AABB9@0<BA??CCABBCBBB?B(:?:CA
@93R
CTCAGGGCTGCCAGACACTTTTCCTGGAGACACCATTTGGTTCTCAGAACTTCCTGGGCTCTGGGAAGAGCTTGAGCAGTCCAGGTCAGCCAGGGCACCTG
+
@@@FFFFFHHHHHJJJJIIJEGIIJIGGGGIIGIIGHIGGEGHIJIIF?FHHJGII@BFGIGGGHED=CHEFFFF3@CCCCCCCD;CCCCD?ADDDDDD?C
@93S
GGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGC
+
B@CFFFFFGHHHHJJJJJJJIJJJJIIJIIJIGCHGIIJJJJIIIIHHHHHHHFFFFCDDD?ADEDDCDDDDDDBDBBBDDDDDCDDBBDB<BDDDDCACC
@93T
CGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGTCACTCTTCTGTGTCGGTGGGCGGTA
+
CCCFFFFFHFHHHIGCGHFHHJJJJJGHHJIJJGIIJJJFHIIGJJIJJJHHFHHHHHHFCFFEDECEDDDDD############################
@93U
GGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCA
+
CC@FFFFFHHHHHJJJJJJJJJJJJJJJJJGGGIIJJJJJJJIJJJJHHHHHHHFFFDDDDDDEDDDDDDDDDDDDDDDDDDDDBDDDBDDDDDDDADDDB
@93V
GGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCA
+
CCCFFFFFHHHHHIIIJJJJJJJJJJJJJJJJJJJJJIJJJJIJJIJHGHHHHHFFFDDDBBDEDDBDDDDDBDDDDDDDDDDDDDDDDDDDDDDDDDDDB
@93W
GCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAG
+
1?@DDDDDHFHDHIEID?GF?CFDEGDHIIGIEHIGGHIEIGGIGIICHHEFHFDECBB?ACDCCBCCBCC@;;@B<>BBBCCB?8?B8?@BBCC@AAC<3
@93X
CTGCTGCTTTCCTCAAGGGAGGCTTGAGGCCGGACCTCTCTCCCAGTCTCCTTGGTGGGGGTGCCCTTTTGCTGGTGGCGCCATCAGATACATCAAATTCT
+
@@@DFFFFFGFHDGI>DEGIEG?FGH;CGCGEEBHHGHIIJJIJIIFIII=CAD>?CEBC?8;@CDDDCCAC@:33(8?B<552,4::CCC((:A>@4>@C
@93Y
CTGAGTGCCATCTGCTGGCACGGGGGTGCCCACACCCGCAGGGCAGCCCAGGGCTTCGCCAGGCAGACCCTGCAGGGGTGCTCCTCCGCAGGCTTCCTTAG
+
CCCFFFFFHGHHHJIJGIJJJJJJJJFGIJJJJJJHHHFDDDDDBDDDDDDDDDDDDDDDDDBDBDB@BDCDDCCBBB9@BDCCDDDDDDDDDDDDDDDCD
@93Z
CATCTGCTGGCACGGGGGTGCCCACACCCGCAGGGCAGCCCAGGGCTTCGCCAGGCAGACCCTGCAGGGGTGCTCCTCCGCAGGCTTCCTTAGGGATTGCA
+
CCCFFFFFHHHHHJJJJJFHIJJIIJJJJIHGFFDCCDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDD9>?CCDCDDDDBDDBDDDDCDCCCDDDDCCC
@940
CCGGCATTCCTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGT
+
CCCFFFFFHHHHHJJJJIJJJIIJJIJJJIJJJJJJJJJJJGJJJJJJJJJHHGBDFDADDDDDDDDDDDDDDDDDCDDDDDDDDDDDDDDDDDDDDDDD8
@941
CTCGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCT
+
@CCFFFFFHHHHGJJGHIGGHJDGIJJFGIIIEFIIIIG>GHHGG@AHDHBBDCC@CABDDDDDCCCCCDB8ABCCDCDDDCCDDDDD<C?DCC@CCB>39
@942
CGGGTGTCACTCTTCTGTCTAAGGAATAGGAACTAAGGTTTTCCTCCACGGCTTGCTCAGGGCTGCCAGACACTTTTCCTGGAGACACCATTTGGTTCTCA
+
BCCFDADFHHGHHJJJJEIIGCHHGGGIIJIJJJIJJJGHIIIJIIHIJJJJIJJGHD4@EHEEEBFFF@AB@@CCD>C@@C9?(5ACD95>CCC8?@CCC
@943
CCAGGTGGTTGGTTGGGGCTGTGCTCTCAGGAGCAGAGGTGTGTGCACAGGTAAGGGTCTGAGTGCCATCTGCTGGCACGGGGGTGCCCACACCCGCAGGG
+
@CBDFDDF@FFFHIJIJJIJJJJIJJJJAFHEIGHIJJC?FBDGHIIHIIE@CDHHH=CHFEFFFFEEEEEECD;>?CCB=?BD<9@DCC@?B8>>@BBB9
@944
CGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGT
+
CCCFFFFFHHHHHJJJJJJJJJJIIJIJJJJJJJDIIJIJJJJJJJJJFIIHFDAEEEDDDDDCDDDDDDDDDDDDDDBDDDBBDD<ACDDDDDDDDCDD9
@945
CGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGTCACTCTTC
+
CCCFFFFFHHHHHJJJJJJJJJJJJIJJJJIJGIIJJJJJJJJIIJIJJJIIHHHHHHFFFFFFEDDBCDDDDCDDDCCDDEDDDDDDDB-5&02:AC:@4
@946
CGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGT
+
C@@FFFFFHHHFFHBGGGGGIIIJJGJJJIJBDHIIFGIGIIDGIGGIEHGHBCCCEDCDDCCDDDDDDDDDDDDDDCDDDDDDDDDDDDDDDDDDDDDD9
@947
CGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJIJJJJJJIHJJJJJIJJJJJJJJHFDCEEEDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDA
@948
CGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGT
+
@@@DDDDDDDDHHA?@FDDEBBEBFBHCEHGIIGEBHCGAGI>@@@G==EHHEC;@CDCC@ACBCCBBB55;B??<?CBBB<<<@BBBCC>C>A#######
@949
GCTGCGGGAGCACAGACCCCACCGTGCCGGCATTCCTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTT
+
CCCFFFDFDHHHGJJJIGIJGHJIHGJJIJJEIGGIJJJJHHA<BEDDABDDDDD?CDAA@BDDDDCEEEDE@>C@4))8<5?BDDBB3998A>CCDDDB<
@94A
CGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCACGCAGCTGGT
+
?@@DFFFFHBFHHIEFGHEGIJGIDGI?GHBDEHIJ8C=CHGCHGHIHIIDHFDD@CDDCDDDBC5;?BDDDDBBBC@AADB???BB@>9A3ABDBBCAA3
@94B
CGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGT
+
CCCFFFFFHHHHHJJJJJJJJJJJJIJJJJJGHJIJJIJJJJJJJFIIJJJGFDBAEEDDDDDDDDBDDBDDDDDDDABDDBDD@DDDDDDDCCDDBACC<
@94C
GGCTTCCTTAGGGATTGCACCAGGAGGCGAAGTGGCCACTGCTGCGGGAGCACAGACCCCACCGTGCCGGCATTCCTCCTCGGCTCCGTGCGGAGTCTCCG
+
@CCFFFFFHHHHHJJJJJJJJJIJJIJJJJJIIJJHIGIJJJJEHGIHFDAACEEDDDDDDDDDBDDDDDDDDDDECDDDDDBBDDDDBBB>BBD?CACD>
@94D
GGCTTCCTTAGGGATTGCACCAGGAGGCGAAGTGGCCACTGCTGCGGGAGCACAGACCCCACCGTGCCGGCATTCCTCCTCGGCTCCGTGCGGAGTCTCCG
+
CCCFFFFFHHHHHFIJJJJJJJJIIJJIJJJJCHHIGGIGJJIEIJJHDEDCEEEDDDDDBDDBDDDDBDDDDDDEDDCDD>BDDDD##############
@94E
GCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTG
+
CCCFFDFFHHFHHIJJJJJJJJIJIJJIJIIIJIJJJIEIIGIIJJIIJGHFFAAEEEDDDDDDDB@BDDBBDDDDDDDBB?BDDDDDDDDDDDCDCCDCC
@94F
CTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGTCACTCTTCTGTGTCGGGGG
+
CCCFFFFFHHHHHJIIJJJJJJJJJJJJJJJJHJJJIJJIJJJJJJIJIIHHHHHHBFFFFEEEEDDDDDEDCCDDDDD######################
@94G
ATGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGTGTCACTCTTCTGTG
+
CCCFFFFFHHHHGJJJJIJJGEGHIJIJHHIJJJJGJJIHGIJIIJJIJJIJGHHHHHFFFFFECEEEDDDDDCCDDECDDDDDDD###############
@94H
TTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGTCACTCTTCTTT
+
+:=4BDDB?DDB:EEA:B;?C8AF<EDD6DE*??6@DDDC=BBEA@CCD2=AC=ACD>D@@AD@;@9AABAB#############################
@94I
CTCGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCT
+
???BDDDDD:<A68CEA:CEID)100?@DBDE>BDBDD?'7B@;@D6(':499=>AAA??''8A>?A##################################
@94J
CATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGG
+
CCCFFFFFHHHHHJJIJJJJJJJJJJIJJJJJJJHIIJJJJJJJJJJIJHFFCEEEEEDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDACDDDDDDDCCDD
@94K
CATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGG
+
CC@FFFFFHHGHHJJJJJJJJJJJIJJJJJJJJJHIJJJJJJIJJJJJJHFFCEEEEEDDDDDDDDDDDDDDDDDDDDDDDDDD<ACDCDDDDDDDDDCCD
@94L
CATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGG
+
CCCFFFFFHHHHHIGIGJJJJGJIJIGJJIJJJIGHJG@FHGIIIJIIIHBD=BEDEEDDDDDDDDDBDDDDDDDDBBDDDDDDBDDDDDDDDDDDCD?CB
@94M
CCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGTGGCACTCCT
+
@@@FFFFDB4ADCFEGBEEHGIJHIIIJJIIJIGGFHGGIHGGGGHIHIIG;(6?EEBEEDB@A;;5??9=CCDDC5<:>9:ACDD@BB############
@94N
CATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGACCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGG
+
@<@DD?ABD:FBBHIFB?;DHHEHCGGI6GGIB>B?BH@F>A>@FHIEGH:BA>ACA>,=5;(5';?&59>@<<<488@8?<@?BBCC>43:<<??#####
@94O
CATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGG
+
C@@FFFFFFHHHHJIIJJIJJJJJJIJJIHIJGIJJJGJJGJGGGJJIEEDDBAEDEEDDCDDDDDDDDDDBBDDABBBBBBDDB@CCCCDDDDCDDC9<?
@94P
ATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGA
+
?881BADBF;DBFEFIIEFFBA?AFCGFFEIBFD@FFFFCFII=@=;@EFD?@96;ACBBB>A;@;>>7>88<?A@BB??@2<02@9:>BB@@B(:<?@B1
@94Q
ATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGA
+
@@@FFFFFGGHHAIJJIGIIGCHIJIIGGIJJJIIGHGHIJJIGIJJJIB?BCEECCDDDDDDB@BDDDD??BCCD@B@BDDDBDCDCDDDDDDC@A?CB8
@94R
GGCGGGTGTCACTCTTCTGTCTAAGGAATAGGAACTAAGGTTTTCCTCCACGGCTTGCTCAGGGCTGCCAGACACTTTTCCTGGAGACACCATTTGGTTCT
+
CCCFFFADFHHHDGGGH@HGIJEGIGEGIEHIHIIHJFIIFHJIIIIGCHHHEFFD<B@:>ACB@BDDBCCDDDD@ACC@C:(>289?CDDD@CC>CBBA:
@94S
TGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAG
+
CCCFFFFEHHGHGIE<GHGI<FGIEGAFHGGGGIIIIIGGIIIIIIGI6BB?CCEEDDD?CCDDDDDDDBDDCDBDDBDDDDDBCDDDDDBCB>AC<CDBD
@94T
AACTAAGGTTTTCCTCCACGGCTTGCTCAGGGCTGCCAGACACTTTTCCTGGAGACACCATTTGGTTCTCAGAACTTCCTGGGCTCTGGGAAGAGCTTGAG
+
@@@FD?DDAFHDHFHIGDGHIEGIBE9CFIIIIGGGIDH>G@DHGHI4CBFHIIIIIAH;CHHEFBEFCEEEE:AAC;@C>3;AABCDDCA?@A<<@C>B@
@94U
CCGCTCCTCGAGGAGCTGGCCATTTGGCCTGCAGCCACTTCTTCCTGAGGACTCAGGGTCATGGCCCTGCCAGCCACCAGGTGGGTGGGTGGGGCTGTGCT
+
;=?DADDDH8FHADEFGE@GAHAA<BG@G<?8?D<?D@GC@BA@DHIAFC==FHIICG==;EEA2);;@C>CC=B?CBB?B,5<'559&055<BBB@####
@94V
TGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAG
+
@<@DDDDDFHH:FGF@FHGEEHIIEGHBHIEFD<FHG4BCGGCE>FAHFE=@ADCC?C>=@@?BBB@B;@?BCAB@0????<58@?ACCCB<B?A?#####
@94W
TGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAG
+
CCCFFFFFHHHHHJJJJIJGGIJIGIJIJJIJGHIIEIJJIJJJJJJJGFFBCEEEDDCDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDCCDDD
@94X
TGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAG
+
CCCFFBFFGHHHHJIIJJJJJJJJJJIJJJIJIACDGHJGIGIJ@HGGHF=?ACEDDDDDC;?BDDDDDDDDDD@B@0<B<BDBDCCCCCDDD>A?ACBDB
@94Y
CTTCGCCAGGCAGACCCTGCAGGGGCGCTCCTCCGCAGGCTTCCTTAGGGATTGCACCAGGAGGCGAAGTGGCCACTGCTGCGGGAGCACAGACCCCACCG
+
@@@;BADDHFHDDAF?FE;CFHFGB)?AHBHHDIBHE<BDDCCCC>>A>A?3;(5>3?A?89?5(55&&8@CBB?BCC>:4>><959<B?9?>A8?#####
@94Z
CTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGTGTCACTCTTCTGTGTCGGTGGACGT
+
CCCFFFFFHHDFHJJIJHIIJJJJGIIIDHIGIJJIIJIJIJJJJJJJJIEH=CHHGFFFFFFEDEEECCDDDDD09&4>A@CDD################
@950
CTTCGCCAGGCAGACCCTGCAGGGGTGCTCCTCCGCAGGCTTCCTTAGGGATTGCACCAGGAGGCGAAGTGGCCACTGCTGCGGGAGCACAGACCCCACCG
+
CCCFFFFFHHHGHJJJIIJJJJJJJFGHIJJJJJJJJJJIJJIJJJEHHHGHFFFFFDEDDDBDDDDDDBDDDDDDDDDDDDDDD>BDBDDDDDDDDDDBB
@951
GGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGG
+
CCCFFFFFHHHHHJJJJJJIIIJJJJJIJIJGIIJJJJJJIJJIJGIFFB?CDEEDECDDDDDDDDDDDDDDDBDDDBDDDDBCDDDDDDDBDCDACBBBD
@952
GGCTTCCTTAGGGATTGCACCAGGAGGCGAAGTGGCCACTGCTGCGGGAGCACAGACCCCACCGTGCCGGCATTCCTCCTCGGCTCCGTGCGGAGTCTCCG
+
CCCFFFFFHGHHHJJJJJJJJJJJIJJJJJIHHIJHIJJJIJIIIJJHFFDDEEEDDDDDDDD@BDDDDDDCDDDEDDDDDDDDDDBDBBDBDBD?CCCC<
@953
GGCTTCCTTAGGGATTGCACCAGGAGGCGAAGTGGCCACTGCTGCGGGAGCACAGACCCCACCGTGCCGGCATTCCTCCTCGGCTCCGTGCGGAGGCTCCG
+
CCCFFFFFHHHHHJJJJJIJJJJJGIIIIJJJGIIJJJJJJJJJJJJHEFDDEEEDDDDDDDDDDDDDDDDDDDDEDDDDDDDDDDD>??59<05&288@5
@954
CTCGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCT
+
@@@DDDDDHFBHAI<?CCDGDGGB00?909?**?F9BAD<:CGA;'6;AEBBAACCC@:;=@(:;5:@A:?BB??@(4>:4:@<::<<29AC:A@######
@955
TCAAATTCTAGNTTTACAGGTCCGCTCCTCGAGGAGCTGGCCATTTGGCCTGCAGCCACTTCTTCCTGAGGACTCAGGGTCATGGCCCTGCCAGCCACCAG
+
@@@DDDDDH>F#2AFFHGGHHGIIIIIIIIDGHGIGGGEBHHFGIGEGGHGIIIIIHHHFHEEE>CECCCCCBCCCCCBCCBC@CACBBB8ACC@BBCBBB
@956
GGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGG
+
CC@FDDFFHHHFFAFG@GDHGGIGHIJJJJEGBDHFF8CGHHGEGAGBF16@B@C?C:=CAB?B@B5&8@B9@?B??@B@BD?C>>>CAACBCCCCC@###
@957
GACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGA
+
@BCFFDFFGHHHHJJJJIJJJJIJJJJJJJGIIGIJJJJIGIIJGIHHB@BEFEDCEEDDDDDDDDBBDDDDDADDDDBBBDCDCCDDDDDDDDCDBBDDB
@958
CTTAGGGATTGCACCAGGAGGCGAAGTGGCCACTGCTGCGGGAGCACAGACCCCACCGTGCCGGCATTCCTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGC
+
<@BFFFFFHHHHHJJJJJJJJJJJJJIJIJJJJJJJJJIJJIHHFFFFEEEDDDDDDDBDDDDDDDDDDEDDDDDBDDDDDDBDDDDDD?CDDDDDDBDDC
@959
ACGGCTTGCTCAGGGCTGCCAGACACTTTTCCTGGAGACACCATTTGGTTCTCAGAACTTCCTGGGCTCTGGGAAGAGCTTGAGCAGTCCAGGTCAGCCAG
+
@@@DDDD1?:??;EF?3@1C?<3::?BFGI*?**?80*)99B(9BF8D.=)==;@FF;@E)=7)=C2=?;?@D############################
@95A
CCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGA
+
CCCFFFFFHGHHHJGIIIGGIJJJJJJJJIJJIIJIJDEHIIGHIJJIHHHHFF8>?@DDDBDBDDDBDDDDDDDDDDDCCCACDDD99A@8??<ADDD?8
@95B
CCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGA
+
@@@DDFAFHHFHHIJGIGIJJJJIDHGGHIEGIIIIEIIIJIDDEHCHEHEEDDEBBDDDDDBDDDDBB?B?BDDDDDCDDDDDDCCCC?BBDB?<ACDBB
@95C
CCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCGCACCTTCAGGCAGCTGGTGGAGGACCTGGA
+
??7B?DDDFFFBFEGI@@CE?EG>1?CFFE<DGBGDFGFF';5()=DFCCAAB@BB>BBBBBBB9>8882&5>95>:?A:49?<?3AB3<?8<@(289<?#
@95D
GGTGTCACTCTTCTGTCTAAGGAATAGGAACTAAGGTTTTCCTCCACGGCTTGCTCAGGGCTGCCAGACACTTTTCCTGGAGACACCATTTGGTTCTCAGA
+
@@?DDDFFHGFHHJJHGJJJJIIJIJIIFIIJEGIIGGGHIIJJHFIBDEBHGHHIIIGGGGEEECEEEB>CBEECE>@>?9(5?C?<5>CCD<<>@CCDC
@95E
GTTGGGGCTGTGCTCTCAGGAGCAGAGGAGTGTGCACAGGTAAGGGTCTGAGTGCCATCTGCTGGCACGGGGGTGCCCACACCCGCAGGGCAGACCAGGGC
+
B@@FDDDDFAHHBGIJIIGGJJGGGEGH)??3:B@GGFGB3?BFFGDF>FFGCHIJICHHII@3AACADB>C;5529?:??825>9<<-9?B><?BCDB<@
@95F
CCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGAC
+
CCCFFFFFHHGHHJJJJJJJJJJIJJIJJIIJJJIJJJJJJ;FHIIJIHHHHGFFDDDDDDDDDDDDDDDDDDDDDDDCDDDCDDCDCDDDDDBDDDDDDD
@95G
CGCCAGGCAGACCCTGCAGGGGTGCTCCTCCGCAGGCTTCCTTAGGGATTGCACCAGGAGGCGAAGTGGCCACTGCCGCGGGAGCACAGACCCCACCGTGC
+
CCCFFFFFHHHHHJJJJIHJJJBHHJIJIIIIJJIJIJJJJJJJIJJEHGHHEHFFFFDDDDDDDD@DDDDDDDDDDDDDDD@B381<ACB?A@8<@@8A@
@95H
CCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGAC
+
CCCFFFFFHHHHHJIIJJIIJJJIJIIJJJJJJJIFIJIBHFGIIIJIHHHHEFFDBDDDDDDDCDDDBDDDDDDDDDDDDDDDDDDCCDBDD<?ACDDBD
@95I
CCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGAC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJIJJJJJJJJJIJGIIJJJJHHHHHFFDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDBDDDDDDD
@95J
CTCGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCT
+
CCCFFFFFHHHHDGI@E?EFGHBGBHI>FGGI<DGBFBF:ABCFH8.;:A=/9,;5>C;;;=BAA?ACACB8AAC@>:>A:>>?A@@B2><@C:>CCB>A<
@95K
CCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGAC
+
@CCFFFFFHHHFHJJJJJJJJJJGIIJJJJIJJJIJJIIBE@CFGIJIHHGHHFFDDDDDDDDDDBDBBDDBDDDDDDDDDDCDDDD<C@A@?BBBDDDDD
@95L
CCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGAC
+
CCCFFFFFHHHHHJJJJJJJIJJJJJJIJJJJJJJJJJIIJIJJIJJJHHHHHFFDDDDDDDDDDDDDBDDDDDDDDDDDDDDDDDDCDDBDBDDDCDDDD
@95M
CCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGCAGGACCTGGAC
+
@7?DDFFFDDHHHJJIGIIJGI;?CFG4CDGGGG4?DBEHG(=DHJIJ3??E?9?ABB'3<@BDDBA@BBB<@>BA?CCCDB<ACC9<+(++(+28<CABB
@95N
CCGCCAACTGCCCACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGAC
+
B@@FFFFFHHH+2AFGIEEIJIJEHIJGGIJJJIIDIJJGI@CGHJIIHHHHHFDDDDDBDDDDDBBDDDDDD@BDDD>CDDDDDDCACDDDDDDDDDD@B
@95O
CCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCGGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGAC
+
BBCFFFFDHHDFHJJIIIGIEGHDCHGGGHGEGEG>:FGGH;FHADG;=;C;,,392,8;<@<<CBA??28?BDDC?::ACDDDDDD<9<BD<8??<?A<B
@95P
CCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGAC
+
CCCFFFFFHHHHHJJJJIIJJIJIJIEIJJJJJJJIIIJJIHHGIIEHHGFHHFFDDDDBDDDDD@BDDDDBDDDDDDDDDDDBDCDCCD?BDDBBDCB?B
@95Q
CGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACC
+
CCCFFFFFHHHFDEIIJIGHGJIJIJIJFG@FGBCHIJ>H@FFGIIHEIGHFFFDDBDDDDDCCBDDBD8?BDBCDDCDDDDD?CDCABBA?B?ACDB<A9
@95R
CTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGTCGCTCTTTTGTTTTGGTTGGAGT
+
;??=DDDDDD<<0@?):E9??C@?@DD4900?4?;D2=;CC<ADEID;@A;;=7ACD77;??;@@@###################################
@95S
CGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACC
+
CCCFFFFFHHHHHJJJJJJJJJIJJIJJJJJJJJJJJJGJGHIJJIJIIJHHHFDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDCCDDDDDDDDDDDDC
@95T
CGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACC
+
CCCFFFFFHHHHHJJJJJJJJJGGIIJJIJJJIJIIJIGIFHIJJJJJJIFHHFDDDDDDDDDDDDDDDDDDBBDDDDDDDDDACDCCDA?BB?BCDDBBC
@95U
CGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCG
+
@@?DDFDDFABFHGGGGGGGHIIJCHGIEHJJGGFHI@/BAGI6E5??EC9?BDD@CCCDDDB<95?A@@C@ACCCCCBB8?CDDCDCDD9A?C@ACC<BD
@95V
CGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACC
+
CCCFFFFFHGGHHJJJIGIIIIGHIIJJGGGJIIGIIJGGDGGGIJJJJIHEFDDDDDDDDDDDDDDBBDDDDDDDDCDDDDDDCCDDBDDD0AACC@BD?
@95W
CGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACC
+
@CCFFFFFHHHHHJJJJIJJJJJJJJJJJJJJJJJJJJJJGHIJJJIJIJHHHFDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDCDDBBDBDDDDDDDD
@95X
TCCTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAG
+
<@@FFDFFHHHFFIE<C@EGBACFCFHGEHHJCHEGECHGGIGFFE5;AHEHF<>A>@=>@CCDDBBDDCCCCCCD<AB>CCDAAC:AC:>?B2><CCDDC
@95Y
CGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACC
+
CC@FFFFFHHFHFIIJJBGIJIJJIJIGGIJIEHFHIG6@CHGGIJJJIIEHHFD>@BDDDDDDDB@BDDDDDDDDDDDDDDDDDDDDD?<?@BD?CBDA9
@95Z
CGTGCACAGGTAAGGGTCTGAGTGCCATCTGCTGGCACGGGGGTGCCCACACCCGCAGGGCAGCCCAGGGCTTCGCCAGGCAGACCCTGCAGGGGTGCTCC
+
@@@DDDDDFD3C?EEF<CFGII+AFHFHIIIIIFGFFIFIGEF:?DDCCCB?BBB?:@;;BB788?B@BB??BBBBBBBBB<BBB<BBBBB9?9@058@@@
@960
CGGGATTGCACCAGGAGGCGAAGTGGCCACTGCTGCGGGAGCACAGACCCCACCGTGCCGGCATTCCTCCTCGGCTCCGTGCGGGGGCTCCGCCTTTCATT
+
CCCFFFFFHHHHHJJJJJJJJJJFHIJJJJJJJJJJJJJBHFHDFFFDDDABDDDDDDDDDDDDDDEDDDDDDDDDDDB?<59>&9&&0?B##########
@961
GGCGAAGTGGCCACTGCTGCGGGAGCACAGACCCCACCGTGCCGGCATTCCTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTG
+
@@CFFADBFHHHGIJJJGJEHIIBDGEFHIGGIGGEGIGDGHGEHFCDDEFCCDCDDDDBDD@8?@BDBB<CACDD><9?CCA@AADDDCCD@BBD@BD8?
@962
CTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGCCTCTGTCCTGCAAGGGTCTTCTAGGGTCTCCGAGGCCGGCGGCACTC
+
=;?DADA:DC<ABEGGGCDFG<@FBFBF=C@?@:?/?D<B:@;/1@777@)7((61;;@AAC>>@C###################################
@963
CGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACC
+
@@CF=DBAFFFH8AFBEEEHDFFG>GG>FDACEFEGGGGIECHEGG@DEGBEFD>@BBBBDB?CBAB0??B8;2:A>ACCBCDCDDCCBDA?0?ACDDDDD
@964
CGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGACCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACC
+
@@BDDDDEHHFFAH=HIIJJJJGGI<DDFHGIII@H:DGHEHHH4@EEGHH>=/99;@?@(89@88<888<8>BCCDCDCDD@CD?(9?############
@965
CGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACC
+
CCCFFFFFHGGHHIGIGGIJIFGIJJFGGGGIIEGGIJJICGIBGGGIEHHHHBCDDDDDDDDCB98?BDDDDDCDD>CDDDBDCC<AB???<1?CC@BDC
@966
CTCGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCT
+
B@BFFFFFHHHHGIJEHFHGIIJIIGIBHDGEFIJIGIIBBHIJGBCGEFFDDACDDDDBDD?CCCDDCC?AB@DDDDCCCDDACCDBACDDCDC:@A>>?
@967
CGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACC
+
B@B?DFFFHGHHGJJGGIJIJEGIEIJIIJJJI@B@G?A>@C<GGB=DHH>A'58;>:?ABBDAB???88@?@?ACCCCCDDBC@?3<7?AB<<8<??<BC
@968
CGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGGTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCCAGCAGCTGGTGGAGGACCTGGACC
+
@@@DBDFDHHHG4AEHHIGHC;CFH@FCHIH:?<F@FHGB5=(81@EEHEA??D';;;8A8BDDDD088<@@>8@?+::39<B?@(+9<1?@@A#######
@969
CTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGTCACTCTTCTGTCTAAGGAATAGGAACTAAGGTTTTCCTCCACGGCTTGCTCCAGGGTGCCC
+
BB@FFFDDGFAHGJ<CFGIJJIIIDGHHEHBHHIIJG'80&8>3@@C8>(((93::?3>:3(:3>84:A@C((>?4:>>C#####################
@96A
CAGGAGGCGAAGTGGCCACTGCTGCGGGAGCACAGACCCCACCGTGCCGGCATTCCTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCT
+
CCCFFFFFHHHHHJJJJIJJJJJIJJJJGIJIIJIJJJJHHHFFBDDDDD@BDDDEDDDDDDDDDDDDBDDDD>B?CCDDDDDDDDDCEEDDDDDDCBDD7
@96B
GCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCG
+
CCCFFFFFHHHHHJJJJJJJJIJJJJJJJJJJJIJJJGIHHIJJIIJJJJJHHFDDDDDDDDDDDDDBBDDBDDDDDDDDDDDDDACBBDDDDDDDDDDDD
@96C
CACGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGTCACTCTTCTGTCTAAGGAATAGG
+
CCCFFFFFHHHHHJJIJIIJJJJJJGIGIJJJJJJIJJJJJGIIHIJGIGEHHHFFFFFFFDEEEEEDDDDDDD<&00&8@CC>A@4(4>A3:><(9@###
@96D
GCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJIJJJJIIJJJIJHIJJJJGIJIJIHHFDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDCDDDDDDDDDDDCDDD
@96E
GCCAACTGCACACACGACCTGTACATGATCATGCGGGAGCGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCG
+
CCCFFFFFHHHHHJJJJJJJJJJJIIJJJJJJJIJJJIJ6FHHIHHHHFFFFDDDDDDDDDDCDDDBDBDDDDDDCDDDDDBD@CCCDDDDBD@CDDBDDB
@96F
GCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCG
+
CCCFFFFFHGHHHJJJJJJJJJJIJJJJJJJJIJJJJJJCHIJJJJJEIIJHHFDDDDDDDDDDBDDDDDDBDCDCDDDDDDDDDCDB@BD?BDCCD@DDD
@96G
GCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCG
+
@?;?D?DDHDF>FIGD:?GGIIGECFCAHHHCFEGI60@;=F.@AHEHIGCHFE?BBBBBBC399??B?BBBBCCCCCCBABCCC?<08A<88ACCBB??0
@96H
GCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCG
+
CCCFFFFFHHHGHJJJHIJJIFIJJJJJJJJJJEIJIIJCHIIIJJJJJJJHHFDDDDDDDDDBDDDDDDDDDACD>CCDCDADD<C?ABDBBACC?ADCD
@96I
GCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCG
+
CCCFDFADHDHHHIIHIIJJIHCEHGIIIEIIG*BDGIECHHIJF1BDG@CB/=ADBBA?BDCDBBD@B?BBDDDDDCDD<?C@A?<?<BBBABCC?A??B
@96J
CGCCAGGCAGACCCTGCAGGGGTGCTCCTCCGCAGGCTTCCTTAGGGATTGCACCAGGAGGCGAAGTGGCCACTGCTGCGGGAGCACAGACCCCACCGTGC
+
CCCFFFFFHHFHHJJGIJHIJJHHIJJIJJJIJJIJJJJJJJJJJIJIGHHHHHFFFFCBCDDDDDBCDDDDDDDDDDDDDDDDDDDDDDBDBDDD@B<A<
@96K
CACCAGGAGGCGAAGTGGCCACTGCTGCGGGAGCACAGACCCCACCGTGCCGGCATTCCTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCG
+
C@CFFFFF?HBFDFGGIGGG>GGIIEIB@FBHIGIIEG@EH9BEBAA?C?AB=BDDCDCDCCD?B>BDDDBA@;59>@(9@C@@B5<@C:4(4@CC#####
@96L
GCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCG
+
CCCFFFFFHHHHHJJJJJJJJJIJIIIJJJJJJJJJJJJIIIGIGIJJJJIHHFDDDDDDDDCBDDDDDDDDDDDD@CDDDDDDC?CBBDDDDDCDDBBDD
@96M
CACAGGTAAGGGTCTGAGTGCCATCTGCTGGCACGGGGGTGCCCACACCCGCAGGGCAGCCCAGGGCTTCGCCAGGCAGACCCTGCAGGGGTGCTCCTCCG
+
CCCFFFDFHHHHDHIJJJFIIJJJJJJJJIJJJIIJJJJ5=EFFFFDDDDDDDDDDBDDDDDBDDDDDDDDDDDDDBDD<AAACDDDDBDD<<?ACDDDD>
@96N
CCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGT
+
CC@FFFFFHHHHHJIGIJGJJJIIJIJIJFHGIJIJIJHIIJIJFIJJJIGHEDDDDDDDDDBDDDDDDDBDDDDDDDDDDDDCCC?BDDDDDCDBABCD5
@96O
CCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGT
+
CCCFFFFFHHHHHJJJJJJJIJJJJJJJJJJJJJJJIIDHIIJJJJJJJJJHFDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDCDBDDDDDDDDDDDD>
@96P
TGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGGGGCTCTTCTTTCTAAGGGAAAAGGAAAAAGGGG
+
??@DD<?AFFBFHIIGGIAAHHAA@GBBGHHDHIGEHGIIIIIIIG@GGFCA8CFHIICGGCB######################################
@96Q
GGCCGCTGCTGCGGGAGCACAGACCCCACCGTGCCGGCATTCCTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCT
+
CCCFFFFFHGHHHJIGIGJJJJJIJJJGIIJGIJIIIHFFFFFEEEEEBD?BDD@?BBDBBD?CDDDDDBDDA@:ADCDDCDCCBDB?BB<<?B<<9@?C@
@96R
CAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTG
+
@<??DDD8DDHHHB:FHIIAF>GGCEHIIEBA@GAD:(8B@DGB;=CHII6=A>:@BBBC@<?<18<@<9<@?CCCCBC?>>?<<?8?BBA<(92?A9902
@96S
CCACCGTGCCGGCATTCCTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCT
+
CCCFFFFFHHHHHJJJJJJJJIJIIJJGIGDHHIJIJGIHIJHHHFFCFFEEEEEEECCDDDDDDBBDDDD;B<?CCCDDDBDDDDDDDDBABDDDDDDCD
@96T
CGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCA
+
@<<DDDDDDFDFHAF?FEFGFF?FHDB9B<?FH<D@?@6;CEHE@DBE85?(6A@>>B>=1:@<AA:>@(++94@3:A::>C((22+9<CCCA>A@9>?A>
@96U
CAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTG
+
@CCFFFFFHHHAHIIIJIIGHIIIIIJIIJJIJIIJJBFEGG>GGIIIIIFFDDDDDDBDDDDDDDDDD@@CD>CCCBDBDCDCDDDBBBDDDDD@BD>9<
@96V
ACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTC
+
@C@FFFFFHHHHHJJIJHJJJJJJIIJIIIJJJJGDHIJJJJJJJJJGIFDDDDDDDDDDDDDDDDDD@CC@CCDBCBCCD?CDDDDBDDDDDBDDB9BAB
@96W
CTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGGCACTCTTCTGTCTAAGGAATAGG
+
@@CFFFFDHGF=FHIGIIICHGIIIIIIIIIGEGBDBCGHGHGECHIIIIEG=?CEEFDDED;@CCDCED?BBDB##########################
@96X
CTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCC
+
CCCFFFFFHHHHHJJIJJJJJJIJJJJJIJJJHIBFGIJJIIIJIHIJHFBDDDDDDDDDDDDDDDDDDDDDDDDDDDDDCDDDDDDDDCDDBDCD9BBDD
@96Y
CTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCC
+
C@@FFFFFHHHHHJJJIIJJJJJIJJEIGJJGIJGHIJJJJJIJJHJJHFDDDDDBDCDDDBDD@DDDDDCDDDDDDDDDCCDDDDDDDDDDDD?09ABBC
@96Z
TGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCT
+
CCCFFFFFHGHHDHHHIIIJJJJJJJIGHIIEH6?FGIJCHGIIIIJHFFCCDDDCCDDBDDDDDDDDDDDDDDDDCDDA??<AB?BBCDDADDD>A<ACD
@970
GCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTT
+
CCCFFFFFHHHHHJIJIIIJIIJGJJGJJGGIGHGIIJJJJJIIIIHFFDCDDDDCDDBDDBDDDDCDDDDDDDDDCDCDDBDDD8ACCDBACDBDDBDDD
@971
GCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGCGTCCTT
+
@@@DFFADG?FFFDGGIIFEHDHCGIIIA0??(0?4BDH88=CC@BBBDB6=BB3;?BDD@?@BBDCCC44@A?19AC3(<(2<@?B(9<8AC########
@972
GCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCCCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTT
+
???DD8+ADADDDIE?,+<C>AB+?ECEDA06?84BD=7=BC9=)--:<89?@??A;;=8<==???:>A>>A?<?9>>+(88<08<1<>??(999?2<AA#
@973
TCTGAGTGCCATCTGCTGGCACGGGGGTGCCCACACCCGCAGGGCAGCCCAGGGCTTCGCCAGGCAGACCCTGCAGGGGTGCTCCTCCGCAGGCTTCCTTA
+
@@CFFFFEHHHHHJJJEGGIGIGGIII:AGHJGIIIHHDDB<>??@BBDD@BDDBBDCDDDBBDB<?BDBBC?BDA89@09@@ACCDA@B0599?ACCA34
@974
CTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGGCCCTCTTCTGTGTCGGGGGGCGG
+
BCCFFFFFHHHHHIJGIHIHJJIGJJJIFEHGGIJCHIGGDDFGIJJGIJGH?C>HHFDFFFEEEEDEECDDDBB##########################
@975
GCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGTCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTT
+
@CCDDDFFFAAHHEHDHHIIBBFGIDGG8@GH0BFI<CBDGG;F9FA>:?B?ACCCAAB?(8<@BDCCACDCDDDDCC9?888<?BBC(2+<A55?#####
@976
CGGCCACCAGGTGGTTGGTTGGGGCTGTGCTCTCAGGAGCAGAGGTGTGTGCACAGGTAAGGGTCTGAGTGCCATCTGCTGGCACGGGGGTGCCCACACCC
+
@CCFFDFFDFHFFJGEHIHGHIIFIJIHEEIIHHIIJFJF@GGGG@FDHGCEHEAHF@C@DDEECCC<CCCDC>C?CDDCCC<?CDD@BD>BBCC@BB?@9
@977
GCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTT
+
@@@FFFFFHHFHFIEGHIIJIIHGJJIIJIGGDGGDGIGGIGEFHBADED>BBDAC?BD?@DDDDDDDDDDDDDDDDDDDDDDB?BBCDDDDD@<BBDCDA
@978
CTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGTGTCACTCTTCTGTCTAAGGAATAGG
+
CCCFFFFFHHCFDHICGHHBHHGHGIJEDHDDGGI@GIHIHIIJJJIHGBHD=AHHHFEDDFCCEEEDDCDDBD###########################
@979
TTCCTCCGCAGGCTTCCTTAGGGATTGCACCAGGAGGCGAAGTGGCCACTGCTGCGGGAGCACAGACCCCACCGTGCCGGCATTCCTCCTCGGCTCCGTGC
+
CC@FFFFADAHFHIBGIEI<EH@FHIIIIIFDGE;DGGFAA8-7=EEECHHFBDD>>/8=@<BDDD?18??;B98AB?>>@<@ADCCCCCCBB7?BB####
@97A
TGGGTGGGCACTGGCTCACTGCCTGGACAGCTTGTGGGAAGCGAGGTGCTGGCAGAGTTCAAGGCTCTCTCCTTGCTCTCTGCTGTTGGGGTCTCGGCTGC
+
@@@FFFDF?HHHHJIHGGIIJJJIGIJI@GIIJIFHIIDHIIJJJJAGGIJHFHHFFDDF>CCCCEDDDDDDCCCCDDDDDDCDCCDD85@>BD@C@?@B@
@97B
GCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTT
+
@C<FFFFFAFFFFGGGIGCHCEE9EGGBFDBD78?FH@HIIII.;;<=DACAB@CCB?BBB@<?-<CCCCCCB9A>:?33?B??B<ACCBBBCC>@BA###
@97C
GCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTT
+
@@CFFFFFHGHHHJJJJJJJIJJJJJJIIGGH?DHBHIFIIJJJJIHFFDDDDDDDDDD?BDDDDBDDDDDDDDDDDD<ADAB@<ABDDD8?CB0<<AC@C
@97D
GCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTT
+
@@@FFFFFDHFHFGEGIIIIIIIIIGGGGIIGIIEIIIIIIHIGHHHFFDCCDDDDDBBBDBDDD?C?CCCCBC?CCCCDDBBDDDDDDDBDCD<BDDCDC
@97E
CGCAGGCTTCCTTAGGGATTGCACCAGGAGGCGAAGTGGCCACTGCTGCGGGAGCACAGACCCCACCGTGCCGGCATTCCTCCTCGGCTCCGTGCGGAGTC
+
CCCFFFFFHHGHHJJJIJJJJJJJJJIJIJJIIIIJGGJJJJIIJJIJJHHFDDDDDDDDDDDDDDDDBDDDDDDDDDDEDDDDDBDDDDDD<B@<B####
@97F
GTCTGAGTGCCATCTGCTGGCACGGGGGTGCCCACACCCGCAGGGCAGCCCAGGGCTTCGCCAGGCAGACCCTGCAGGGGGGCTCCTCCGCAGGCTTCCTT
+
@@@BDDA:CFHFFHGBHG?GG@GHIIII7AE7CDGHAAE6=>CBBB@88?<99?@@(83;5@?@B@?B<??B?<??A?@B&555<@>?>-<<>@B?33:>>
@97G
CACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTA
+
@<@BDFFFAHH6?EHIIII@HIIIIIEIGGIBHHBGGDEHIIBEIHDDFCBC@C@=A??BBBB@8@ACCCCBCCC@CCCB1<BBBB<9<<?CBBBB?C:@>
@97H
CGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGTGGTACTCTTCTGTGCTGGTGGACGTCA
+
@?@DD<DDFAC:?:D2*1?FBGDDABBBF<9B79BFE>>8BFFIECCEED.777?E?CCD@BDA;.>B=?@##############################
@97I
CACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCCTACC
+
CCCFFFFFHHHFHGAHGH<HCHIIIIIGEFFGGIIGHIGHG@FHFHFFFDAEDDDDBDDDDBBDDDCDCDCDDDDCCBADB?BDDDDDDDB<B88A>>AB2
@97J
CGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGTCACTCTTCTGTGTCGGTGGACGTCA
+
CCCFFFFFHHHHGJJGHIJJJJJJJJFDGIJIIGIJIJIGIJIJJJIIIJIGHHHHHHGFFDFEEEDEDDDDB############################
@97K
CACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACC
+
CCCFFFFFHHHHHJJJJJJJJIJJJJJJJFHJJJJJJJIJJJJJHHFFFDDEEDDDDDDDDDDDDDDDDDDDDDDCDDBDDDBDDDD@BDD>BADDDCCDD
@97L
CACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACC
+
@@@DDDDDFDDHFGGGEIJJJICBEBHBDGFDIIGGGIHIJI8EHEFFECACED;?B(8<?BBCDDCCCDCDCCC?CB?A@?B<?CBBACB9<<ACA@:CA
@97M
CACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACC
+
BCBFFFFDHHHHHJJJIHIJJIIGGHIIJDGGHGEEHG@HGABHHHFFFDBEEDDDBDDDDBDDDDDDDDDDDDCCDDDDDDD<9?BDDDD9A?2:>@CDA
@97N
CTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGTCACTCCTTTCGGTGGGCGGCACG
+
<B@FFFFFHHDAFFHGHGHIGIGHGGIIAHHHGJJHGIEGIIIIGJH;CHHI?EHHHFBEDF;C>CEAEDDBDD###########################
@97O
GCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGTCACTCTTCTGTGTCGGTGGACGTC
+
@@@FFFFFHDFHHJDHFGHIJEHEHIIJIIIIJJHICFHIJJJIJJIIIJHG?EEFFFFDDEEEE>CCCDDD@9&00)8AA@:CACDCCC:5>BB@8@@##
@97P
CTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGTCACTC
+
CCCFFFFFHHHHHJJJJJJJJIIJIJJJFEGGIEHFHIJJJJEHIIGEHCGHHHHFFFFFFECEEECDDD=CDDDDDDDDDCDDEDDDDDDDD########
@97Q
CTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGTGTCACTCTTCTGTCTTAGGAATACG
+
@@1BD?DDFA<DAAF@CFCCDD?CFDFI>FGH>@G(B=FHC==@G@G3==1;CEHEE;37);;@@C:;(5=BB############################
@97R
CACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGT
+
CCCFFFFFGHFHHIJJJIIJJJJJIJIGIIJJJJIIJIJGJIJJHHFFFBCCDDDDDDDDDDDDDDDDDDDDDCDDDDDDDDDDDBDDD@B?BDDDDDDD<
@97S
GTGCCATCTGCTGGCATGGGGGTGCCCACACCCGCAGGGCAGCCCAGGGCTTCGCCAGGCAGACCCTGCAGGGGTGCTCCTCCGCAGGCTTCCTTAGGGAT
+
@BCFFFFFHGGHHJIFHIGIIIDFIJJJJJJJJGIHGHIJHHHBEDEDDC=ACBBD@@D@5?BDBDDDDDCBD@BDDDDDCCC<<B@BDDC?CCA@CDDCC
@97T
CGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCA
+
@@@DDDDDFFFDF8?2???G?CFGICEGFG<?F9B??7@B(<F'.(-5:55,6;;A;;>?B:;9:(5>@28?AB::@A34:<B@BB+9<BA@:>AB(3?@@
@97U
TTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGGCACTCTTCTGTGTCGGGGGA
+
@@@DDDDDHFHFA<A@FFGA?D?<DBDDHIGBF@AFHIIGIIGGD@@G>G>;AEA;BDEDE@CCCCCCCDCCCBBBB########################
@97V
CGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGTGACTCTTCTGTGTCGGTGGGGGTCA
+
@@CFFFDADFFA8E@ACEFGGEEHII?BBHGIFEE;DDHF=C=FGEHGGGECE>EE>AAD;?@CDCA;A@D?#############################
@97W
TTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGTCACTCTTCTGTGTCGGTGGA
+
@CCFFFFFGHGHHIJJJJJJHIIJHHJJJJIHIJIJJJEGIEIIGGHIJJFFHHHBDEFFFEECBCDDDEDDDBDDDD&90)2@AC###############
@97X
CACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGT
+
@@@FFFFFHHHFDIJJJJEDHHGHGGA:BGHGH7FHHGHFEEHGH<DDFCCD?C=;=B@BBDC@>CC<ABCCC<C?ADD<8<<??8<A<0<A<CCDCA?##
@97Y
CACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGT
+
@@CFFFFFHHHHHIIJJJIJIIIIJDHFGGIIFJIJIIIIGGIJHBDFFFEDDCDDDBDDBDDDCCDBDDDDCC<B?ABDDDDDD@DCBBBBACDDCCDB0
@97Z
GGCGAAGTGGCCACTGCTGCGGGAGCACAGACCCCACCGGGCCGGCATTCCTCCTCGGCTCCGTGAGGGGGCTCCGCTTTGCATTCTTTCTCGGATCCGTG
+
:1;7:@@<CB??D;C>3<AEFIIDA:B>B9;BAFFF>@F':44>88?:A3;@:>?<55??7?#######################################
@980
CACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGT
+
CCCFFFFFHHHHHJJJJJJJJJJJIIJHIJJJJIJJJJJJJIJJHHFFFFEDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDD@
@981
GGACTCAGGGTCATGGCCCTGCCAGCCACCAGGTGGTTGGTTGGGGCTGTGCTCTCAGGAGCAGAGGTGTGTGCACAGGTAAGGGTCTGAGTGCCATCTGC
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJGHJHHIJJJJIJJJJJIHIJHHHHHFFFFDEDDDABCDDDDEDDDDCCDDDD<?CDDDCCDDDDCDDD
@982
CACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGT
+
@<@DDFF@>DHFHEGIFHGE>@FHIJI0?ADEEBGIDGIHEAEIEHFFFFC2==7?B?@BBDDCCCCBCBCCDCDDDDDB<BDDDBBD30<?AC@>CCDD2
@983
CCCACACCCGCAGGGCAGCCCAGGGCTTCGCAAGGCAGACCCTGCAGGGGTGCTCCTCCGCAGACTTCCTTAGGGATTGCCACAGGAGGCGAAGCGGCACC
+
C@CDFFFFHHFHF<F=D@HGHEGEGIGGI>FGHGI(=FGHIIIHHGHDB>>>BCCCCDDDDDD&8@A@@################################
@984
CGGTCTTCTAGGGTCTCAGAGGCGGGGGTCACTCTTCTGTCTAAGGAATAGGAACTAAGGTTTTCCTCCACGGCTTGCTCAGGGCGGCCCGACACTTTTTC
+
@@CDFFFFBDHDHGHHJJIJJIIJJI'3339A3555(:338+(3(83>(9393>?@@>3?(:@B4:(+99??#############################
@985
CACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGT
+
@@@FDFFFFFHHHEEHGGIJJHIJIJJBBDFHCBFGCGGIBGHGHBBFFFC=?CDBD?BD?CC:>@CDDDCD9+9?8AB<A8<CB(+309<(2ACDDCC08
@986
CACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGT
+
@@@DDDFFHFHHBEGIDGGIEGIIJJD6BFGCFFEH9FF6@@EHFHFDFF>AABB@??BBDCC@:>>9<A9A3(+8<<@BBB?A<?<350?A?@@>CCD@2
@987
CACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGT
+
@@CFADFFHFHG>FGH9CEHGG:FGEG;DFEGHIGIIIIIIII@EEDEFFECCCBBB<<=B@CCACCCCBCCCCCCA?((+29?A<2?B5<2?CCACCC@8
@988
CACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGT
+
CCCFFFFFHHHHHJJJJJJJJIJJJJJFHGIJJIJJJJIIIIJHHHFFFFEDDDDDDDBDDDDCCDD<CBDDD<CD?BD??ACDDBDDD@B8?CCDCCD##
@989
TTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGGCACTCTTTTTCG
+
B@@FFFFFHHHGGIJJIGIJIIGGIJJJJJJJJJJJJJJIGGJGIGIJIII>@CCCEGFEEEB;>ACEAACC??C<CCCDCBBBB################
@98A
TGTGTGCACAGGTAAGGGTCTGAGTGCCATCTGCTGGCACGGGGGTGCCCACACCCGCAGGGCAGCCCAGGGCTTCGCCAGGCAGACCCTGCAGGGGTGCT
+
BCBFFFFFHHHHFFIJJJHHIJIJHIJJJJJJJJJJJJIJJJJJJABEEECDDDDDDDDDDDDDDDDDDDDDDDDDDDDBDDBDDDBBBCCBDCBBB@BBA
@98B
ACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTG
+
@@@F?DDDHBFHBHIGHEGB?GHG>CGCGAH>DGCD?DA<;8AGBH?BCDD?B?BBB@BB@CCA5:<C?CCC3???BB?B?9<<<BA95ABBCC:C@?3<B
@98C
CCGGCATTCCTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGT
+
@@@FFFFFHHHHHJIIIJJJJJGGGIIGE?FHHIB@AEGHGGIIGIIIJC@BHGFDEA??@??BB(:::>>>9@BCDC@ACC?ABDCC<>CCCCC?CCBD#
@98D
CCGGCATTCCTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGT
+
CCCFFFFFHHHGHIJIHIIIJIECEHHAF8B@FG:@@FH4@FHIEECDAD@8AE?8?A(;9'8/3,:(4@&0&57::<C@:>02<<AC:>+>:@C######
@98E
CGCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGGCACTCTTCTGGGTCGGTGGG
+
CCCFFFFFHHHHGHGHJJIJFHIIIJIIIJFHIIIEGIHIGJJJIJJIIJFGFGH?CFFFEEEEDEDDDEDDDDDBB9&&&&08AC@CA############
@98F
CAGGAGGCGAAGTGGCCACCGCTGCGGGAGCACAGACCCCACTGTGCCGGCATTCCTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCT
+
@@@D42@:CFHHHIIIIII9DDGEHGIIBGGIIEEEC=??BCCCCCC3;>=BBC@CCCAC9-57?BBB8?BBB;>(9>>@5@5<@C@CCDCEE3@C:55?8
@98G
ACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTG
+
@@@DFF?DDFAFHGGGGIJIAFGEAH:BDAHGBCAFHGIIJD6AAEEEDE?AA?=?@?:9:?ACCDBDBCDC?CB<AB?<ACDDBB<><AA8>CCCCC522
@98H
GCACAGGTAAGGGTCTGAGTGCCATCTGCTGGCACGGGGGTGCCCACACCCGCAGGGCAGCCCAGGGCTTCGCCAGGCAGACCCTGCAGGGGTGCTCCTCC
+
CCCFFFFDHHHHHHIJJJJHIJJIJJJJJJGIJJJJJJJJ@EEFFEFDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDBABDDDDDDBD9@BDDDDDD
@98I
CCCCACCGTGCCGGCATTCCTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTC
+
@CCFFFFFHHHHHIJJJJIIIJJIJGGIIJJIHCBAG/A5CCCHEB<BB>;ADEDDDCDDD:@@<?B;+855>09(9@ACDB@DBC@A>A:@B1<<ACCAA
@98J
CCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGTGTCACTCTTCTGTGTCGGTGGACG
+
CCCFFFFFHHHHHJJJHGIJJIJJIIJJGHIJJJJJCHHIIJGIJJIJIIHHHEHHFFFEFFDEEDEEDCDDD?BD09)4@A:@>A4+4::4:5@######
@98K
GACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGAC
+
CCCFFDDFHFGHHJIGIJJIE6CGFGIFCFC@FFIIIIIII;AGHHHGHF7BBDCDDDCCC@CCBABCCC?C??ABDBD?C@BBDD>A?A@ACCC>5???@
@98L
TTCCTGGGCTCTGGGAAGAGCTTGAGCAGTCCAGGTCAGCCAGGGCACCTGGGCCAGAAGGCCCGCCCCACACCTCAGCACTCTGGGGGGCAGGATGGCCG
+
CCCFFFDFHFHHHJJJHHIIJJJIIJJJJJIIHIIIIIBGIIIDHJJIJIJJIJJJIGJHGHHHFECDDDDDDBDDDDDDDDCC>@C<B9<5>9?######
@98M
CTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTC
+
CCCFFFFFHHHHHJJJJJJIJFHIIJJJJJJJJJJIJJJJJJJJHHHHFFFCDDEDDDDDDDDDDDDDDDDDDDDBDDDDDDB>BBDDDDDDDBDDBDDBD
@98N
CAGGTAAGGGTCTGAGTGCCATCTGCTGGCACGGGGGTGCCCACACCCGCAGGGCAGCCCAGGGCTTCGCCAGGCAGACCCTGCAGGGGTGCTCCTCCGCC
+
@BCFDDDFHGFHHGGIEHHIJJIFIJGHHGGIGEGIIGHHHGHBEFCDBDDDDDBB8BBDDBBDDDDDDDDBBDD?@BDBBCDD9?BB>>>?CCCCDC@@#
@98O
GCCACTGCTGCGGGAGCACAGACCCCACCGTGCCGGCATTCCTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTC
+
CCCFFFFFGHGHHIGGIJIIGHHGIJGIIIBGGDHIJHHBAHHHHFFFDDCDDDBDDDD/;8?CACDDDDDDDEEECEEDDDDBDBBBDBA?5<>59<?CC
@98P
GTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCA
+
BB@FDFFFGHHHHIGHIIB@;@AGGICHEHEGBHIFIHIJIJGHHB;?BBCDEECACDCDDD<(99AB<BDBAB<CABDDB0828@::(+392?@######
@98Q
CATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCG
+
C@CFFFFFHHHHHIHJHIJJJJJGGIIJHGGJJJIJJJIFEEFFHFFFDE>CE>CCDDDDCCCCDDDDDDBDDDBDD@BDBDDDDDDDD?BDDDDBD?@?>
@98R
CCCCGAGAAGCTGGCATGGGGGGGTCCTCTCCTGCTCCGCTCCTACCGTCGTCCTCCTCCACCTCCTGCGGGGCCTTTTGCTGCCTCACTGCTGCTTTCCT
+
@@7DBDDDDFFDDEEHGHGIGB1-)6<ACC>8@>@C@C@BBB6CC>85?BBB@B?>CC<>9+2<88C:>;BBB>98@:>ACCCC?CC@BCCACA::4>A>A
@98S
TGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGAC
+
???DDDDD4DDD:E+AEEI@EEEIIEDDIIID@DIIDCCDDADD=?D@@A>>@A???AA?=??=<?=>><?<>??>58(2>:>>A9>(<22><>7<A<559
@98T
CTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGTGTCACTCTTCTGTGTCGGTGG
+
CCCFFFFFHHHHHJFHHIIGJJGHIJJJJJJIHGIJIJJJJJIJJIIJJJEFEHHHBDFFFEEEEDDDDDEDDDDDDDB######################
@98U
TGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGAC
+
@C@FFFFFHHHHHJHIJJJJHJJIJIJIIJJJJJJJJJJJJFHHFFDEEEEEEDDDDDDDCDDDDDBDDDDDDDDDDDDDDDDDDDB?BBBDDDBDDDD<B
@98V
TGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGAC
+
CCCFFFFFHHHHGJHHJJJJJJJJJJJJJJJJIJJJJJIJJGHHFFFDEEEEDDDDDDDDCDDBDDDDDDDDDDDD@BABDDDDDCDDDDDDDDDDDBBDD
@98W
CCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGTGGCACTCTTGTTGGTGGACGTCAC
+
CCCFFFFFHHHHHJJJIJGHIJJJIJJJJFHIGIJJGIIIJJJJJJJJJJHIH?EHFFFFFFDEEEEEDDDDDDDD#########################
@98X
TGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGAC
+
CCCFFFFFGFHHGIHICHHGGGIIEIDDHIHGGIIJJJJJJEAE?;<BECECEDBDBCCDCDDBDDBDDCCBDDDB<AB<CCCDDC<BB0?BD>BDDDD>@
@98Y
CAAGGGTCTTCTAGGGTCTCAGAGGCGGGTGTCACTCTTCTGTCTAAGGAATAGGAACTAAGGGTTTCCTCCACGGCTTGCTCAGGGCTGCCAGACACTTT
+
CC@FFFDDHHGHHJJJFGHIIJIJJJJII4@5..=7A=?;=3;@BA>)>(;6;>A-;5;>C>A(5<<5>A@?<<8>55<38@:4>>A##############
@98Z
GTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGTGTCACTCTTCTGTCTAAGGAATAGGAACTAAGGT
+
CCCFFFFFHGHHHBHIJJIGHGHJIHHIIJB@GIJIJJIJEIH;BGGIIJHGGHIIHGGJHHHDD####################################
@990
CTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGTGTCACTCTTCTGTCTTAGGAATAGG
+
CCCFFFFFHGHHHIIJHHGIJIIIJJJIGCHGHGEGGEGHJJJIGHHHIIIIEHHHGFFFFFDEEEEEEDDDDBD&503:@::4>:34>@A##########
@991
GGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACGTGAGTGCT
+
@@@BDADEFHHFFHIIJGFHJJIIJIJJIJIJBFHHJJJJJJFIIJJJHFHHHFFDC(;ACDBDDDDBD29ACCDACBBBDDD8<?BCBD><&0??B@CD@
@992
GGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACGTGAGTGCTG
+
@CCFDFFFHHGGAGIFGAHHIJIIGIGIDEGGCDGGIJJ@HICGIGDHGEACEFFECD2;@BBDDD?A<ACDCCDCBDBB?B@5<24<5<B-9?B?:ACCC
@993
CTCCACGGCTTGCTCAGGGCTGCCAGACACTTTTCCTGGAGACACCATTTGGTTCTCAGAACTTCCTGGGCTCTGGGAAGAGCTTGAGCAGTCCAGGTCAG
+
@@@DDDDDFDHF=DF:<FF<C:;F?1:C>>9BDH<?B@A>8?D>FHEIII=C6;;@AAH?EE@C3;?@DE;;AC>@C?C=<<?CCC?A::9>9ACC?(::?
@994
CTCAGGGCTGCCAGACACTTTTCCTGGAGACACCATTTGGTTCTCAGAACTTCCTGGGCTCTGGGAAGAGCTTGAGCAGTCCAGGTCAGCCAGGGCACCTG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJIIJJJJJIJJJJFGGJJJJIJEEFHJJJIJJJJJJJJIJGHGHFFFFFEEDEDEDDDDDDDDDDDDDDDDDDD
@995
CGGGGTGCTCCTCCGCAGGCTTCCTTAGGGATTGAACCAGGAGGCGAAGTGGCCACTGCTGCGGGAGCACAGACCCCACCGGACCGGCCTTCCTCCTCGGC
+
?;;;B=@D<BFF3C8EGI6GGIIF@DGFIEG@FGBFFEFFECFA7AEBB(.;?AABAB:;;@@BB&078(33>@2<08<@#####################
@996
CTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACGTGAGTGCTGGCTCTG
+
CCCFFFFFHHHHHJJJJJJJJJJJJIJJJJJJJJIJJIIJJJJJCHIDHHHFFFFEEEEDBDDDDDDDDDDDDDDDDDDDDDDDDD<BBB@CCDDDBDDDD
@997
CTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACGTGAGTGCTGGCTCTG
+
@@@FFFFFHHHHHJJJJJJJGHIJJJJJJJJIJIB)>CGFGHIIHIJJDHFFFDEECEEDBBBDDDDDDDBDDDDDDBDDDB<BB>5?AB@ACD@CDCDAC
@998
CTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACGTGAGTGCTGGCTCTG
+
BCCFDFFFGHHGHIJIJJJIJIJJJIJJJJJIJJJJJIIJJIIHDGEIHGHBFFFEEEEDBDDDDDCDDDB<A?B@BDDBCDDDDDDDDBCCCDDDDDDCC
@999
GGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGTCACTCTTCTGTCTAAGGAATAGGAACTAAGGGTTTTCTCCACGGCTTTCTCCGGGC
+
@C@FFFFFHHHGHJJJJJIACGIJGIJJGHHIIGIGIJIJIG,25-(8(9+93>(3>@:A3<:>:>C3(424:A(9(+2?(4:>ACC##############
@99A
TGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACGTGAGTGCTGGCTCTGG
+
CCCFFFFFHHHHHJJJJJJJJJJJGJJJJJJJJIJJGIJJJJJGGIHIHHHFFFFCEEDBD?BDDDDDDDDDDDDBDDDDDBDDD>BDDACCDDDDDDDC@
@99B
GGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACGTGAGTGCTGGCTCTGGC
+
CCCFFFFDFHHHHJJJIJIIIIGDGHIGIJJJBHHIIIGIIIIIAEHFEE=BDFFCEDDDBDDDDCC9=?BDDD@BD@CDDDDD<B?B>CD@C:?<>CACD
@99C
GGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACGTGAGTGCTGGCTCTGGC
+
CCCFFFFFHGHHHJJIJIJJIIGBHJJFHJJJJIHEHEGGIJ8C;D;AEFEFFFFCCDDBDDCDDDDCDB@??BBDDDDDDBBB9?AB@CC@@@BCDDDCC
@99D
GCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACGTGAGTGCTGGCTCTGGCC
+
BC@FDDFFFFHHHJJJJJJICHHIIJGIJJDIIIJEFFHGIIJJIIJHHHFFFFFEBBDDDCDDCDCB@BDDDBDBDDB@>B@@BDDCCDEDC@CCCC3:<
@99E
CGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACGTGAGTGCTGGCTCTGGCCTGGTGC
+
CCCFFFFFHHHHHFGHJJJEHBGGHGIIJJGIGIIFHIIIJJJHHHIJJJGEHHHHFFFFEA=BBDDBDDBDBDDDDDD@@@CCC@ABDDC>C@?CBD@?C
@99F
CATCCATTTTGTCCCAGTCGAGGTGGTAAGAGCCCCGAGAAGCTGGCATGGGGGGGTCCTCTCCTGCTCCGCTCCTACCGTCGTCCTCCTCCACCTCCTGC
+
CCCFFFFFHHGHHJJIJBHGGII@EHCFIGIIIJJJIDHIJIJIBGGGIIIIGHDB57?AC@?3>:>>@CBDBDBDDDDBBB>&8?@CD3?##########
@99G
GCGAAGTGGCCACTGCTGCGGGAGCACAGACCCCACCGTGCCGGCATTCCTCATCGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGC
+
@@@FFDADFFHDCHEGI>BGHEIGFAFHCGIJJHFHIIAABHE8=8<;CECE(;CCBBDDDD2<>B3052>ACDB>>5<3:C>>>:>4:AC&&+8>?9?@B
@99H
CAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACGTGAGTGCTGGCTCTGGCCTGGTGCCACCCGCCTA
+
CCCFFFFFHHHHHJJJJJJJJJJJJGHJGJJIJJJJJIJJJDGHIJJJJJIIGGIJHHHFFFFDDDD@DDDCDDEDDDDDDCDCDDDDACCDDDDDDDDD@
@99I
AGGGTCTTCTAGGGTCTCAGAGGCGGGTGGCACTCTTCTGTCTAAGGAATAGGAACTAAGGTTTTCCTCCACGGCTTGCTCAGGGCTGCCAGACACTTTTC
+
@CCFDDFDHHGHGJFHIJJJFJJJJJH'5'.7@;77;3.7;>;);;@3;;;;@9A;>AC@C(5@?(:@:99<8;<9>98:+(39?<15(8:4878<(4@C#
@99J
CAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACGTGAGTGCTGGCTCTGGCCTGGTGGGACCCGCCTA
+
???DDDB?;B1:D>DBBE9C@+2AF)CE8;D?389BDB;@D?B(8=@4=@;@AC;5A;=?;;@@>;?8=<?(5:3>A########################
@99K
AGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACGTGAGTGCTGGCTCTGGCCTGGTGCCACCCGCCTAT
+
@@@FFFFFHHHHHJJJEIJIEGIJGIEHIGIHIGIIGHBF@DHHIJEIIGHHIGHIHHG=DE@3>B;BBD>CCEDC7AC9CACB@@A4<@CDCDDDD<<B>
@99L
CGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACGTGAGAGCTGGCTCTGGCCTGGTGCCACCCGCCTAT
+
+::DDDD=AFDBFF<FF3EGA?<E:E;)::0?FDFA)BGFI?BFF>FFA@E(=-;;C>?=3;>>;3,,98((2(3<(9>A3@>@>?(+(4<@@<>B99@##
@99M
GGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACGTGAGTGCTGGCTCTGGGCTGGTGCCACCCGCCTATGCC
+
@@<DDFFFHHHHGJIGIIIJJDGHEGGHIJJFEGIJJIIBDFGIGGGGBFGFHHI?EHHF>AB>@??:>C:::?CDCC3(8?<B(3><>CBBB355<::>C
@99N
GGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACGTGAGTGCTGGCTCTGGCCTGGTGCCACCCGCCTATGCC
+
CCCFFFFFHHHHGIJJJJIJJGIJIJJIJJJIJJJJIGGIJJJJJIJJIIJHGIIHHHHFEDBB@BB>CCEDCDDDDDCDDDBD@CDDCDDDDDDB<CACD
@99O
CTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGGCCCTCTTCTGTCTTAGGGA
+
@@@DDDDDHHHFHIHIIIICH??GHIIIGGIGBCGCGGICFGGIIGEGEEC?E?EH?CEEECCCCC@CCCDCCCBB?BB######################
@99P
CGGCTTGCTCAGGGCTGCCAGACACTTTTCCTGGAGACACCATTTGGTTCTCAGAACTTCCTGGGCTCTGGGAAGAGCTTGAGCAGTCCAGGTCAGCCAGG
+
@@@DDDABHFFDHIF>CFEHBFDGHCHHGBGB@EA?BF?DHGGGGGGDECBCFDEDFEG@E@CHDFFC>?BD;@?AAC@5;=CC>?:(,:@C@A@CCC8<?
@99Q
CGGCATTCCTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCCCTTTGTGCTGGGACTCTGTCCTGCAAGGGTC
+
CCCFFFFFHGHGGJIJJIJJJFGGGIEG@F>BHDGEBG@E@FGGGE@@DEB>EED?6?18/38?8?@##################################
@99R
CCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACGTGAGTGCTGGCTCTGGCCTGGTGCCACCCGCCTATGCCCC
+
CCCFFFFFHHHHHJJJJIJHIJFHIFHIJJJJJJJGIIIJIJIJIIGHFH;FIIIJHHGFDDDBDACDEDDDDDDDDDDDDDCCCDDDDDDDDDDDDCDDD
@99S
CCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGTGTCACTCTTCTGTCTAAGGAATAGGAACTAAGGGTTTCCTCCACG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJEHIIIJIJJJGIIJJJJJIIJJD'9,5;>>CAC@CACCCBCCD:9:::A:>ACCCCC18AD<>@AC?CB
@99T
CGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCA
+
CCCFFFFFHDFDFEG8CEEHGGIIJCDFIIGIIGIIIBHE=BHGFDHEH?/;ACCE:@?BD<CC@CCDB8??CDCCCDA@C<CCDB2>ACCD@CCB?CDD@
@99U
CCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACGTGAGTGCTGGCTCTGGCCTGGTGCCACCCGCCTATGCCCC
+
@CCFFFFFHGHFFGHIIJJHHGEFFGGIGGD>DHG<DFFHHIJIIBFH1C@FBHDDEE=DABDDD5@CECCDDDCC>@AA@A39A<:AB3>@93@AA:AC?
@99V
CCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACGTGAGTGCTGGCTCTGGCCTGGTGCCACCCGCCTATGCCCCT
+
@CCFFFFFHHHHHJJJJJHIJIJJJJJJJJJJJJHIGGIJJJJJIHIJJJIIJJJJHHFDDDDDCCDEDDDDDDDDDDDDDCDDDDDDDBDDDDDDDDDD?
@99W
CCCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGTTACTCCTTTGTGTCGGTGGACGT
+
@?@FFFFFHFCFAEECHGAHECGEFHIG?@DGIJJAFHGIG=CAFGG;)=@;6?ECDFEEF@6>CE:C>>?BDDB##########################
@99X
GGCGAAGTGGCCACTGCTGCGGGAGCACAGACCCCACCGTGCCGGCATTCCTCCTCGGCTCCGTGCGGCGTCTCCCCTTTGCCTTCTTTCTCTGCTCCCCG
+
CCCFFFFFGHHHHJIIJIJJJJIHIIJJIJEGGJJIIJG@CGHEHBA>CABCDDCDDBBDDDB######################################
@99Y
CAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACACAGAAGAGTGACACCCGCCTCTGAGACCCTAGAA
+
CCCFFFFFHHHHHJJJJJIJJJJJJFGIFHIIJJIJJIJJIHHHIJJJJJJJIJGIHHHFFFFDDDDDDDDDDCA:A@CDABDB>BDDDCCDCCBDDDCDC
@99Z
CGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACACAGAAGA
+
@CCFFFFFHHGHGJJJJJJJIJJJIJJJJJIGJJJJJJJJJJJJIIHHHHCDDEFCDDDDDDDDDDDD@BDDDDDDDDDDDBDDDDDDDDDDDDDD<?>AA
@9A0
CAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACACAGAAGAGTGACACCCGCCTCTGAGACCCTAGAA
+
CCCFFFFFHHHHHJJJJIJJJJJJJGHIIJIGIJJJJIIIIGIFHIIGIJHGHIGIHHHEFFFCCDBDDDDDDDDACDDCCBDDBDDDDCCDDDDDDDDDC
@9A1
CCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACACAGAAGAGTGACACCCGCCTCTG
+
CCCFFFFFHHHHHIJJJIJJJJJJJJJJJJJIJJIIGIJJJJHIJJJIJJGFBHEFFFFCEEDCDBDDDDDDDDDBDDDCBDDCDB+>CDDDDDBBD@BCC
@9A2
CCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACACAGAAGAGTGACACCCGCCTCTGAGACCCTAGA
+
?@@DDB:=D=<D?<C<+:AD8FCGE;:CAFCFFFD;;DCFF<@FFIB>@FF@;-65-5?>?5@(39;9=@@BB>ABB@3>>A209@95@BB33:@??@33@
@9A3
TCGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGTGACCCTTCTTTG
+
@C@FFFFFHHHFHIIIGGHJEFEGGGGHDDGGIGHIIIHHIIJEIGDHHIEHHHHC@D>CFDDCAACCDCDDD???CDD:ABDBDD###############
@9A4
CCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACACAGAAGAGTGACACCCGCCTCTGAGACCCTAGA
+
@CCFFFFDDBF=FHGGIJJJJJJIGIFHIGHG?FHAGGGIGHHHHHHIIGHGGAGHEAEDFFFBCDDBDCBD@A><:>CCCD?@DBBDDDDCCCA<A???C
@9A5
CCGGCATTCCTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGGCTCCGCTTTGTGCTGGGGCTCTGTCCTGCAAGGGG
+
@CCFFFFFHHHHHJJJJJJJJJGE:DG)8)9BBG<BAHH@9=CG7CG4=774=???D/.58;B'8&8<<?>9-9B(49:((:?&)5<C<A:A3(((:>??#
@9A6
TGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACACAGAAGAGTGACACCC
+
@@CFFFDFHDFFHJJJJJJIJJJIGIJIJJJGIJIGIIIIGIJDEHCHHFCDCDFCEED;BABCDDDDDB?BDDBBBB8A?>BBDDDDCDCCD(::AACD>
@9A7
CTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACACAGAAGAGTGACACC
+
CCCFFFFFHHHHHJJJJJJJJJJJJIJJIJIJJIIJIIJJJIJJEGIGEFEBEFFEDEEDDDDDDDDDDDDBD?BDDDDDDDDDDDDCBDDDDD@CDDD@B
@9A8
TTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGTGTCACTCTTCTGTGTCGGGGGACGC
+
@@@DDDDDD?ADHEAF@F>AGHHGFFG>DBFGAHCGEGIGGIGGHGG@DHDE6?EEEEEED=;>;>@CC@###############################
@9A9
GCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTACTT
+
@C@DDFDFHHFHFI?GHIFIEHGBGEHHGIEH7?DFHGGIIIEHBEEDDCBCBBCAB??8?@B@@A>CCC@CBCBCCC?CBCBB?A19A?BBCC5?A####
@9AA
CTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGGCACTCTTCTGTGTCGGGGGGCGC
+
@@@DDDDDFHDDHIGEE?EEGGHIIGIEGDHIEEGEGGBDDBAFCFG@@C@C?CCEHFDFDFBCECEDEDDDBDD##########################
@9AB
CTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACACAGAAGAGTGACACC
+
@@@DDDDDHFDAFIIIIIIGGE98B=DFCGGGGHCGHGIIIIFICGEHEFFDEEEC>AC@BBBBCCCCCCB??8?@BB??CBBB<5<C83@C?<4>@AC:<
@9AC
GCCCACTGCTGCGGGAGCACAGACCCCACCGTGCCGGCATTCCTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCCGGGTCT
+
CCCFFFFFHHHHHIJFHHJJJJIIIJJJIIJIJGGHIHIHHHCEHFFFFDDDDBD?B?;B07(3@4@77;BB3((:@(:@#####################
@9AD
TGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGTCACTCTTCTGTCTAAGGAATAGGAACTAAGGTTTTTCTCCACGGCTTTCTCAGG
+
BC@FFFFFHHHHHJJJJJJJJCGIJJJJJJJHIJJGJIJJJJJH'5)&+9399@33333>(>:C49:::A###############################
@9AE
CAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACACAGAAGAGTGACACCCGCCTCTGAGACCCTAGAA
+
@@CFADBDFHHHAEGHIIIIGGEBD?FEHGCEGIIIIGGII@BBCDCHGGGGGDHGHEEBDDEC8?DDC?AC?>B,:@C@CBDDDDDDDC@@>C?ACCCC>
@9AF
CGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGTGTCACTCTTGTCGGTGGACGTCACGGTAAGGACACGG
+
@CCFFDFEFHHGFEIIBHIIIJJJJJIJDGIIGIJIJJII?FFHGIBGHIHGHIGEHJJJHFB20)4>@################################
@9AG
CGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGTGTCACTCTTGTCGGTGGACGTCACGGT
+
CCCFFFFFFHHHHJJGIIJJJJJJJIDHIJJJJGJJJJIIJJIJJ)@GIJDDHHHHHHHFCDFEEEDEDDDD@############################
@9AH
CTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGTGTCACTCTTCTGTGTCGGTGGACGT
+
@@CFFFFFHHHDFIJJJIIJJIGEHIJIHIJIEGIFGHGJJHIJJJJIIIII=CHHHFFFFFFDCEEEEDDDDDB)99>>@::>@################
@9AI
GCGGGAGCACAGACCCCACCGTGCCGGCATTCCTCCTCGGCTCCGTGCGGGGGCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGGCTCCGCTTTGTG
+
CCCFFFFFHHHHHJJJJJJJJHIIJJJIJJJJJJJJIIJJIIJHHC=9=A'0&&02<&5&5@3+::A:AD###############################
@9AJ
CGCCGGGAGGCGAAGTGGCCACTGCTGCGGGAGCACAGACCCCACCGTGCCGGCATTCCTCCTCGGGTCCGTGCGGAGTCTCCGCTTCGCATTCTTCCTCG
+
C@CFFFFAHHHFHIGGHIJJIJJJGJIJJJJJHHFFFFD@DDDDDDDDBDDBDBBDDDEDDDDDBBBA;ABDBB>BBDBDDCDDBDD-<B@@DCCD@CDDD
@9AK
CCCGCATGGACAAGCCCGCCAACTGCAAACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCGCTCCCAGAGGCCCACCTTCAAGCAGCTG
+
8=?;=)@1<A<3A2A1C6@?::1CC*?*0)))?7('7=F4)8.)8@;9;77:55'3(,;AA<<((,,,85;B&&&0-<@BBB???0(+&((3:+:A???9>
@9AL
TGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCC
+
@C@DFFADHHHHHIIJJJJJIJJJGHG@CHFGHDEHIDGGHIJIIFGHDGEGHGEFFEEEEEDDDDDDDDCDCDEEDDDDDDDDDDD>B<ACCCCDD:?@@
@9AM
GCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGTGTCACTCTTCTGTGTCGGTGGGCGTCACGGTAAGGA
+
C@@FFFDBHFHDFIAFBAEFHEGICGCFGIHCEHGHAFEGGFHDGGGEHCCCFGGEHIIIGHCC)0)4(:>>CC:@#########################
@9AN
TCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGTGTCACTCTTGGCGGTGGACGGCACCGGAAGG
+
@@@FBDFDGHDFFIJGGIGIJJHCHIEIGIGIJJEFGHABFFFHIIGGHJ@ADECEHEEE=?7?DDDD#################################
@9AO
CCCCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGG
+
@C@FFFDFHHHGGJIJJHGHCHHJJJJJIEIGGIC>GHIEIGGJJII=CHHEHEEFFFFDCCDDBDDDDDCDDDDDDDDDBBB<<>>CCCCCCC@CCDBBB
@9AP
CTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGTGTCACTCTTCTGTGTCGGGGGACGT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJHIJJJJJIJJJJIIJJJJJJJJHIAHHHHFFFFFFEEEEEEDDDDDD)904:::>>A################
@9AQ
CTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGTGTCACTCTTCTGTGTCGGTGGACGTCACGGTAAGGACACGGTCCAGGTCCTCCCC
+
CCCFFFFFHHHHHJJJJJJJJJFHIJJJJJJJIJJJJJJJJJJJH5>9;A>CCAC>@;@CA>=@,58++505?B<@#########################
@9AR
CCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACACAGAAGAGTGACACCCGCCTCTGAGACCCTAGAAGACCCTT
+
CCCFFFFFGHHHHJJIJJGIJEIJIIJIJJJJJJFHDHIJJIHHJGIEIHIIIJJJHHFFDEECDDDB;ACDDDDDDDDDDDDCDCDDDDCDDCDDDDDDC
@9AS
AGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGG
+
?@@FFFFFFHGGGIJBHIIIJIJIHIJGEHIIIGIJJJJJJIJJJJIJHHEFFDDEDCCDDCDDDEDCCDDD9;8ACDDD@D:ACC<<B@>B>A?BCCDD?
@9AT
CCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACACAGAAGAGTGACACCCGCCTCTGAGACCCTAGA
+
CCCFFFFFHHHHHJJJJJJJJJJJJJFHIGJJIIJIIIGIJJHGIIJJJGGIIGIIHHHFFFFEDDDDDDDCCDCD:ACCACDDDDDDDDDDCCABBDDDD
@9AU
CCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGTGTCACTCTTCTGTGTCCGGGGGGC
+
@@?BBADDFFFA+@@@1C?F<CD@GBGII@F@><?DCFBB9=CFFI@E@@@EF6=?DDDDB@@>BABDBBBB?BB##########################
@9AV
CTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGTCACTCTTCTGTGTCGGTGGGCGT
+
CCCFFFFFHHHHHJJGJGGIJJJJJJJIHIIJIIIAHHGJJIIIJJJIJJIJHHHHHFFFEFFEEEEEEDDDDDB##########################
@9AW
GCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCGGTACATGATCATGCGGGAGTGCAGGCAGGCCGCGCCCT
+
???D?DDB?==D<A:A?E?:33))1)?)?8C@DI>??D)BD?8@85A8;7?=7..;5?@@#########################################
@9AX
CGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGTCACTCTTCTTTGTCGGTGGGCGTCA
+
CCCFFFFFHHHGHIJJIJJJIJJJJJJIJIJJJGIIIIGHIHJIJGIIJJIEHGHHHHHFDFFEEEEEDDDD#############################
@9AY
CGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGTGTCACTCTTCTGTGTCGGTGGACGTCACGGGAAGGGC
+
CC@FFDFFHHHHHJJJJJJJJJIHIJJIJJJJJIJJIJJIHGIIHJIJIIJHHJJJEIJJHFD######################################
@9AZ
CAGAGGACCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACACAGAAGAGTGACACCCGCCTCTGAGACCCTAGAA
+
1?@;:=+=F8AFHGEFGGGHGIGIIFDH@CGEFHHIGAGHAFH@CHEFDFEBHIGDEHEFDEB?CB3=?BCC>?<,55>A>@B<B@B@AA<A:>?B9?CCC
@9B0
CCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACACAGAAGAGTGACACCCGCCTCTG
+
CCCFFFFFHHHHFHIJJIJJJJJJJJJIIJJJJIJJHJJGIJJJJJJJIIJHHHEFFFFEEEDCDDDDDDDDDDBBDDDDDDDDDB>@CCDABD@BDDDDC
@9B1
CAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACACAGAAGAGTGACACCCGCCTCTGAGACCCTAGAA
+
BC@DDFDFHHHHHJJJIHGJIGIJJ@GH@HHGIJIJIEGIJDHIJJGGGIIIHHGIHEHDEFEDDBDDDDCDCDD,>ACD>?BDBD>BDDDDDDBDDCCCC
@9B2
CTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCC
+
CCCDFFFFHGHHHJJJGIJIJJJJJJJJIJJIEIBFHHIIGIJIJIIJHFDDDDDDCDDBDDDDDDDDDDDDDDDDDDCD9?BBBDDBBCDDDDD@58<AC
@9B3
GTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGTGTTACTCTTCTGTGGCGGTGGACGTCACCGCAAG
+
@@CFBDFFFFFFFE@FHIIFGGIIIIBGGEAHGFFGHIIEGECDCFHHIGDGEDEHGGCGEHHB@####################################
@9B4
GCCCCACCGTGCCGGCATTCCTCCTCGGCTCCGTGCGGAGTCTCAGCTTTGCATTCTTCCTCGGCTCCGTGAGGAGTCTCCGCTTTGTGTTGGGACTCTGT
+
CCCFFFFFHFHHHJJIJJJJJJJJJJJJJIIIGBDFGIAHAEHHHHFFFFEEEEEEEEEDDDBDDDDD@<B?BBAB9?CCCBD<BBCCCCD??B88?CCA@
@9B5
GGGCTTCCTTAGGGATTGCACCAGGAGGCGAAGTGGCCACTGCTGCGGGAGCACAGACCCCACCGTGCCGGCATTCCTCCTCGGCTCCGTGCGGGGGCTCC
+
B@@FFFDFHHHHHGIJJJJJJJJJJGGJDHJBHFGIJJGJJIJEGIHGF??CDEDDDBDDD?BDDDD@ABDD;@CDDDDDDCDDDD@@B############
@9B6
GCCACTGCTGCGGGAGCACAGACCCCACCGTGCCGGCATTCCTCCTCGGCTCCGTGCGGAGCCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTC
+
@@@DDDDDBHHFFGGGGHIJGEHIGI;GGIIGHIJBG8@EH?AEFFDFDDDDDDBDB@/87&8>3<;@BB0:@DDDDEDDD:405@BDDD80<-05&8?34
@9B7
GAAGTGGATGGCGCCTGCGGCCTTGTTTGACCGAGTCTACACTCACCAGAGTGACGTCTGGTCCTTTGGGGTCCTGCTCTGGGCGCTCTTCACGCTGGGCG
+
+==DB8;2AB?+@EEE9+@EAAA9?DDCB4B3@(@7=BCA7@C@3==7(.()..;?;>A@A########################################
@9B8
GCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACAAGAGTGACACCCGCCTCT
+
@@CF?ED@FHHFHIJIJHGEHHHHI;GHGIHGGIGGIJJJIEHIIJHFGHH@BDFEB;ABDDDCDDCD?B8?@BBDDDDBBB-<<9?(:(>>@@09595<:
@9B9
GCGGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGG
+
@@<D?DA?ABFAC??<<@HHI?A9F<4C6))):)?)???AG@-@7@C4'-5?D7?>:6@1>2;;;>;>>@CC3@C##########################
@9BA
CCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACACAGAAGAGTGACACCCGCCTCTG
+
CCCFFFFFHGGHHJEFGGIHHJIHHII>FIIJJJJJIHE2CGCFHHIJIFG:AHFFFFFECCDDDBB(8?<?CADDD@BDBCDDCD>@@CDDBDDBDBDC>
@9BB
CTTCAAGCCGCTGAAGGAGGGCCACAGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGCTCATGCGGGAGTGCTGGCATGCAGCGCCCTCCA
+
??@BDDDD7:F@?1?EBBF1):?C7)0?D9?83BB;98?=@66'5@CE37A3?==88>BBB@A>>@@##################################
@9BC
GATACATCAAATTCTAGTTTTACAGGTCCGCTCCTCGAGGAGCTGGCCATTTGGCCTGCAGCCACTTCTTTCTGAGGACTCAGGGTCATGGTCCTGCCAGC
+
@<<DDDDBC8BAA<F?4A@FGHCH:CAF3)21?):?:))80B?(9DGE=C=@E)).8;(7=7=67@?7?B);@@;.=;A;?####################
@9BD
GGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACACAGAAGAGT
+
@CCFDFEFHHHGHJJJGIJIIIJJJJJIJJIBHIJJJJJJJJHIJJHGIFHHHFFFDDDCED@BDDBDDDDDD@CCD@BB@DDDDDDBB<BBDDDCCDC@#
@9BE
CTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGTGTCCCTCCTGTCGGTGGACGTCCCG
+
@@@FFFFFHHFDHJJBGBFDHIJJJJJJHGIJIJIGIIIJIIGHHJJIEHEC=AEHHFFFFFEEDEAACDDDD@###########################
@9BF
CGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGTCTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGGCACTCTTCTGTCTCACGAACAGGGA
+
?@@BDD1AFD)8DFGBEEGEEIIIGFGB@D4?F;B;B<=<C=FCFFCFF1==@CEC==)?);@?>@@@@?B##############################
@9BG
CGGCTCCGTGCGGAGTCTCCGCTTTGCCTTCTTCCTCGGCTCCGTGCGGCGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTCGGGGCTCA
+
@@@DADDDFFADF:@+*:?FBDAGIB?*?G?FFBB<?6A;CEF/6;BEF'988;<>',5-<@@9>@>@?################################
@9BH
CGGGAGTGCTGNCATGCCGCGCCCTCCCAGAGCCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTAGCGGGACGTCAATCGACACAGACGA
+
??7DDA?<A:A#2ACFFF8)?11?@FFGABFC*8CF@FFIBEEEACA;?A@@;),665(5;=?59?3;8?###############################
@9BI
CGGCTTCGTGCNGAGTCTCCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGGCTTCTAGGGTCTCA
+
=>=AAAAABA+#22?+2?<<AAAAABA?>A4?B9AA>AAA=<;7=<AAA6=;7;?@@=<==??===>?====5=>9>8;?=;??;<&)5;<?==?=3;983
@9BJ
TGGGAGTTTCTGCGGGCGCGGCGGCCCCCGGGCCTGGACTCCTCCTTCGACACCTGCAAGCCGCCCGAGCAGCAGCTCACCTTCCAGGACCTGGTGTCCTG
+
@@CA;DA;BFFHHIHG?FFG<FB6@BB=B7@B@BB?/+88(>>C>CA>???BBB9>ACCCBB;B@>>B3&09ABBB?@:@BC###################
@9BK
CCCCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACCTGATCATGCGGG
+
?;?BDD<ADHHFFC222+A=HHE>DEGFFA*0*00?9?D*09(.7'5;C2@AEH;>CEDA;=?B>BB;;1?>::@>@B>><@&)9:4>(:(34>>ACCB@0
@9BL
TCCACCTCCTGCGGGGCCTTTTGCTGCCTCAATGCTGCTTTCCTCAAGGGAGGCTTGAGGCCGGACCTCTCTCCCAGTCTACTTGGTGGGGGTGCCCTTTT
+
??@DBDDDD3BFAF6:@DDG<B<BF?BCA=C8@CA=CDHG;@=7A>==);('3;=C>;;A?B8=7B8C3>CCCA9A#########################
@9BM
CCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGGCACTCTTCTGTCTAAGGAATAGGG
+
CCCDFFFFHFFHHJIJAGIIJEHEHIGFCGIGGHDFHIIIHIJJIG@=DGGEHHHHFFFFFDEDECCCC@BDD9&0&&08<?3@@>34>A3>(3:?A####
@9BN
GGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCCCCGACACAGAAGAGG
+
B@CFFFFFHGHHHJJJGIJIIJJJJJJIJIJCHGIIEIIJJIJJEGJJJEHHHDFFDDDEDDDDDD;?<A:@A(>><??@22(9?&299@D##########
@9BO
CCGCTTTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGCGGCGGGGGGCACTCTT
+
@@@FFFFDFHHHHBHIGGI>DFHG=8CGGEGGHGGIIIEGHGCH8=FEEE;CEHHGFDFF;@@C3>A@?>=@CC(;55??CCDD#################
@9BP
CTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGTGTCACTCTTGTCGGTGGACGGCACG
+
CCCFFFFFHHHHHJJJJIIJJJJJJJJIFHIJJJJJJJJJJJJJJJJIIJIIHHFHHFFDFFFDEEEEEDDDDDB59044:44+>:>@#############
@9BQ
CCCGTACCCCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCA
+
@<@?DDDD<FFDD1F9E;FF<CEDCHBFB>FEGGA>GF838=C@)BF@(;8'?5A;BCCCB@(;35?BB?=BB-9?C>@CCCB8555>>@C(4:>:@:>AA
@9BR
ACCAGACACTTTTCCTGGAGACACCATTTGGTTCTCAGAACTTCCTGGGCTCTGGGAAGAGCTTGAGCAGTCCAGGTCAGCCAGGGCACCTGGGCCAGAAG
+
1?@FFFFFHGGHGIIII<@H9FEHHHIIIFHIGIEHHIGIIGIHGEHBHHFHIHGHIIIIIIIIIIGHEGEEHEEFDDD@C@BC??BBCCCCB@ABBBB3?
@9BS
CTTTGGGGTCCNGCTCTGGGAGATCTTCACGCTGGGGGGCTCCCCGTACCCCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCA
+
@@@FFFFF<FH#2AFGI@<FFHDGHAHGGIHIIIIGIGDDDDBBDBBBDDCB8@D/<ACDCDCDCC8?2?AACDDDDDCDDDCC@CDDABB3902<0853<
@9BT
CTGCTTTCCTCAAGGCAGGCTTGAGGCCGGACCTCTCTCCCAGTCTCCTTGGTGGGGGGGCCCCTTTGCTGGTGGCGCCATCAGATACCTCAAATTCTAGT
+
???DDD8?DDDDAEE+2+<@FF<AFEEEDI06D38?@DDBCBD=CAAA9CC9A;AAD?&55<<-<8>>>>(((+28;&9529(:3>A>(4:AAAA:4:>A4
@9BU
CGCTCTGCATTCTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGTCACTCTTT
+
@CCFFFFFHHHHHJJIJJJJJIJJIHIIJJHIFHIJIJJJJJIJIJJJJJJJHGHHHHFFFFFECCDACDDDDCDDDDDDDDCCCDDBD@###########
@9BV
GAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGAGCTGGCATGCCGCGCC
+
@@@DDDDDFFD4+AEEHGIII9EFG@6EFGH:?::FG@GGGHE==A;FGEE>EEC;@BB8B;>B@CC;CDDCA(55(::90&)5&+8@A3<C@@C######
@9BW
CGGACCTCTCTCCCAGTCTCCTTGGTGGGGGTGCCCTTTTGCTGGTCGCGCCATCAGATACATCAAATTCTAGTTTTACACGTCCGCTCCTCGCGGCGCTG
+
?@<;4=ADBBDHHEHI3ACHFF>HGC;FH<)07BGG;CAAAFH>).)'-',931;>C@5:>C>5:>>C(:>@C@(:4:>C#####################
@9BX
CCGAGGACAACGTGATGAAGATCGCAGACTTCGGGCTGGCCCGGGACGTGCACAACCTCGACTACTACAAGAAGACAACCAACGGCCGGCTGCCCGGGAAG
+
CCCDFFFFHHGGHGHJIJIIIDEHGCHFGEGGGIJE<FHBGGIJG=?B<?BDCCA@BDD@BDDDDDDDC:CDDCDDDCDDDBBBDBBDBB&008?B#####
@9BY
CTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGTCACTCTTCTGTGTCGGTGGGCGT
+
CCCFFFFFHHHGHJJIJFHIIJIIJJJIFHIIGIJFHHGIIIJJIJIJJJGIEHHHHFFFFFDCEECECDDDDDD##########################
@9BZ
CAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACACAGAAGAGTGACACCCGCCTCTGAGACCCTAGAA
+
CCCFFFFFHHHHHJJJJJJJJJJJJHIJJJJIJJJJJJJJJHJJJJJJJJIJJJJJHHHFFFFDDDDDDDDDDDD>@CDDDDDDDDDDDDDDDDDDDDDDD
@9C0
CCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACACAGAAGAGTGACACCCGCCTCTG
+
CCCFFFFFHHHHHJJJJIJJIJJJJJJJJJJJJJJJGHJIJJJJJIIJJJJHHHFFFFFEEEDDDDDDDDDDDDDDDDDDDDDDDD:ACDCDDDDDCDDDD
@9C1
CTTCCTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGTCACTCTTCTGTGTCGGTGG
+
CCCFFFFFHHHHHIFHIJJJJHGGIGHFIJJGHIIIIJJHJJJJJJJJIIEHGHHHBDFFFEEDEDCDDDECCDDDDDB######################
@9C2
CTCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGTGTCACTCTTCTGTGTGGGGGGGCGT
+
@@=DDDDAF<2C<EE@?1?E<FFGA@GF*99?FFB0/(88CFFEEFIE@ECC(...7>@DDD;A@CAC3;??=B@##########################
@9C3
CCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACACAGAAGAGTGACACCCGCCTCTG
+
BCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJFHJGIJJIJJJJJJJHHHFFFFFEEEDDDDDDDDDDDDDDDDDDDDCCDD>ACDDDDDDDDDDDD
@9C4
TCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACACA
+
CCCFFFFFGHHHHJJJJIJJHIJIIHIJJJJJJIJJJJJHHHFFFFFEEEEEDDDDDCDDDDDBDDDDDDDDD;BDBDDDDDDD?BDDDDDDDDDDDDDDD
@9C5
ACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTG
+
CCCFFFFFFHHHHJJJJJJJJIIJJIFHGIJJJJJGIJDHBHIJHHHFFFFDDDDDDDDDDDDDDDDDDDDD<CDDDDDDDDDDDDDD@BBBDDDDDDDD<
@9C6
CCCGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGTTACACTTCTTTGTTTGGGGGCGG
+
@@@DADFDHHDHDHEIFBFGHIGGGHGBBFFFHIGGGIGEDF@@FGHGGE@C===@CBCDD?EC@EDAA;?BBDD##########################
@9C7
CTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACACAGAAGAGTGACACC
+
@CCFFFFFHGFHHIIJJJJJJJJJJIJJJJJJJGIJJJJJIIJJGHJIHHHFFEFDDEEDD?BDDDDDDDD@BBBBDDDDDDBDDDDDDDDDDD>CDDDDD
@9C8
CGGCTCCGTGCGGAGTCTCCGCTTTGTGCTGGGACTCTGTCCTGCAAGGGTCTTCTAGGGTCTCAGAGGCGGGGGGGACTCTTCTTTGTCGGGGGGCGGCG
+
CCCFFFFFHHHHHIJHIIIJJIJJJJIIJJJJJHHIJIJJJJJJIJJJIJDHHHGHHHHFFFFEEEDEDDDC@############################
@9C9
AGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACAAGAGTGACACCCGCCTCTGAGACCCTAGAAGACCC
+
CCCFFFFFHHHHHJJJJJJJJJJJGIIJJJJJJJJJJIJJJIIJJIIJJJICGGIIHHHFFFDDDDDDDD:>CDDDDDDDDDDDDDDDDDDDDDDDDDDDD
@9CA
GGGAGAGTTTATGGAACTACAGGGACAAAAGTCAAAGGAGTATACCTTGATGCACCTGGAAGCATTAATGGAGTTCCACTCTTAGAGGTAGATTTGGATTC
+
==+<7?<A>BC>B3@2?<AC+?@1?+<A>A*:?*:=A>>A)?*0=ABA=7*/==?=>B>ABB=)87..>4>=>===A)77.;;;>>>@(5;;=;??>?###
@9CB
TGGGACTTGAAGTTATACCAGTAACCTCTACTACAAATAAAATTACGGTACAGCAGGGAAGAACTGGAAACTCAGAGAAAGAAACTGCCCTTCCATCTACA
+
@@@FFFFFGHHHDEG>:EBHEBEHEGHIIIIGIGIIIEHIIGIIIIIIHGDEHEGHHIIIIIIIIIIGGIFHCEHFFFEFCCECCECCCBCCCCCDCCCCC
@9CC
TCCATCTATTGGAAACTCCCATCTTGAGTCATAAGGCAGCTGTATGTTGCTGTTCTCATTTGCCCGTCGCCTGCCTTCTACTCGGCTGATAGTTATAGTCT
+
?8:DDDDBDFHBHGGE>H<C<A:AA?<?2AF>CEDB;GBC@?:?9DBFFG9*99?BH@BGHII@BFHIG6?=?A?@:.;7>CC?@71;9>:@@55;((5;@
@9CD
CCCGACCAAGCACTAGTCCATCTCTTGGAAACTCCCATCTTGAGTCATAAGGCAGCTGTATGTTGCTGTTCTCATTTGCCCGTNNNNNNGNNNNNNACAAG
+
???DBDD6FFFAFIFGEEFDEHIIHIGIFGGGGFHFHIIIBF@F9B?BGI<DGEHIII@GGIIII>4==A?EHC>;CBB@CD###################
@9CE
GGAAACTCAGAGAAAGAAACTGCCCTTCCATCTACAAAAGCTGAGTTTACTTCTCCTCCTTCTTTGTTCAAGACTGGGCTTCCACCGAGCAGGAGATTACC
+
???DDDDAD>B<DE@<9EFF?3AE+<CC+:*?4?EE?DD@?<DDCDECECBBDBDDADCDABCC@=@ADC4@C9AC(6?A2);@>@>:8?###########
@9CF
ATCTCTTGGAAACTCCCATCTTGAGTCATAAGGCAGCTGTATGTTGCTGTTCTCATTTGCCCGTCGCCTGCCTTCTACTCGGCTGATAGTTATAGTTTGAC
+
@CCFFFFFHGFFHIIIIGGGE@HCEEBCBCG@EGIICFEGCCDFB>GC9??BDF:FGG:9BFB@C<EAH9AAE>@C>;>@?C?@B(;:>C###########
@9CG
CTCAGAGAAAGAAACTGCCCTTCCATCTACAAAAGCTGAGTTTACTTCTCCTCCTTCTTTGTTCAAGACTGGGCTTCCACCGAGCAGGAGATTAACTGGGG
+
CCCFFFFFHGHGHJJJIJIIIJJIHIIHIIIIJJIJIGGHDG@EHFIDGIFGHGHIFHIIIIIEIGGCHGI9DHHHFHFFFD<9'95;(8?>::(,:5:?B
@9CH
CTCTTGGAAACTCCCATCTTGAGTCATAAGGCAGCTGTATGTTGCTGTTCTCATTTGCCCGTCGCCTGCCTTCTACTCGGCTGATAGTTATAGTCTGACCG
+
@C@DFFFFHHHHHJIJGIGHIGGJJGJJJIJIGIGIJJHJJJJEGIIJJJGGHIJJIGIIJEIGIIBGEHFEEFFD@DC@CCDBDDDC>;CDDDEEDCA?9
@9CI
CCCGACCAAGCACTAGTCCATCTCTTGGAAACTCCCATCTTGAGTCATAAGGCAGCTGTATGTTGCTGTTCTCATTTGCCCGTCGCCTGCCTTCTACTCGG
+
CCCFFFFFGHHHHJJJJJIJJJJJIJJHJJJJJGIJJJJJJIHIGHIIJJHHIIJJJJHHIIHHIJJIJGFHHHHHHF:@CD>B@DB@BDDDDDDDDDCD7
@9CJ
TGCCCTTCCATCTACAAAAGCTGAGTTTACTTCTCCTCCTTCTTTGTTCAAGACTGGGCTTCCACCGAGCAGGAGATTACCTGGGGCAATTGATGTTATCG
+
C@CFDFFFHHHHHJIJJIIJJEIBHHIIGEIIGIJIIIJJJJJJIJGIJIGIIJJIHHIDEIJJIIJIIHGHF?DF>>CCCCCB@BB@?35>A@CDDE>4<
@9CK
CAGCACTTCTTCTCAGTCTCAGACAAGTACTGCCTCCAGAAAAGCCAATTCAAGCGTTGGGAAGTGGCAGGATCGATATGGGAGGGGCGAATCACCTGATC
+
@<@DDDDDHHHDDH>G?EHCIEEAFGH@EHHEE@?GGEB>BFFEH@G>FGBDFEGEFFGDH=FG=DGEEEH##############################
@9CL
CCATCTTGAGTCATAAGGCAGCTGTATGTTGCTGTTCTCATTTGCCCGTCGCCTGCCTTCTACTCGGCTGATAGTTATAGTCTGAAAAGGNGGNNAGTGGN
+
@C@FFFFFFHFHDGDGIIEIIICHABHHEHHGAHGGIIDHIIIIIIIIHIHHIEHIIIIIIHIIIIIHHFEFFEFDDEEEFED##################
@9CM
TGGAAACTCCCATCTTGAGTCATAAGGCAGCTGTATGTTGCTGTTCTCATTTGCCCGTCGCCTGCCTTCTACTCGGCTGATAGTTATAGTCTAACCGATAA
+
7@;DDDD8:=A?<BGFEF>+AE?BFHB+A<<CF*CF@:C?B?BB>9?4DD9BB4?D07B04;;@@C==AEE37;5?DC>5>AA##################
@9CN
CCATCTTGAGTCATAAGGCAGCTGTATGTTGCTGTTCTCATTTGCCCGTCGCCTGCCTTCTACTCGGCTGATAGTTATAGTCTGACCGATAACATCAATTG
+
@?@D?DDFHHAFBFHIIIFGGIIIHHCD9?E@FG<FHICD9CA@B<FH@BDHGIGIIIEII>CHCGEAHBDFD>7>;CE@@DEC55;>:;5?CCCCC>@DC
@9CO
CCCATCTTGAGTCATAAGGCAGCTGTATGTTGCTGTTCTCATGTGCCCGTCGCCTGCCTTCTACTCGGCTGATAGTTATAGTCTGGGNGNNNNNNNNNNNN
+
@@<?DDD:FFAFHGGFFIG9DCEFB+AHHFH@HGFGGGIDGH*1:??B6DDFHIGE>C@F8=DAAGIHFFEEDEC@DD@>ABC(5=A##############
@9CP
CCCATCTTGAGTCATAAGGCAGCTGTATGTTGCTGTTCTCATTTGCCCGTCGCCTGCCTTCTACTCGGCTGATAGTTATAGTCTGACCGATAACATCAATT
+
CCCFFFFFHHHHHIIIGIIIIGJJJAHIIIIJIJJJIIJJJIIIJHIJIJFGGJJJJJJJJJIJJIJFGHFFFFFEEDEEA@DDDDDCBBBBDACCDDDD>
@9CQ
GGCCGAATCACCTGATCTAAGGAGATTACCTGGGGCAATTGATGTTATCGGTCAGACTATAACTATCAGCCGAGTAGAAGGCAGGCGACGGGCAAATGAGA
+
CCCFFFFFHHHHGJIJJJJJJJIJIJJJJJJJJJJIJJJJJJJJIJJJIJHJHGJIJJJJJJHHHHHHHFFFACBDDDDCDBBDDDDBDDDDDDBDC@CDA
@9CR
GCCGAATCACCTGATCTAAGGAGATTACCTGGGGCAATTGATGTTATCGGTCAGACTATAACTATCAGCCGAGTAGAAGGCAGGCGACGGGCAAATGAGAA
+
@@@DDDD7DHFDDGECHFH?@FH@EHGCGGIGIIIFDBFAACGDGCGIIICAGGCHHGGECHEHI:;CAH><A?CCACCBBBBB@BB959@55@8>>>@>4
@9CS
CAAGCACTAGTCCATCTCTTGGAAACTCCCATCTTGAGTCATAAGGCAGCTGTATGTTGCTGTTCTCATTTGCCCGTCGCCTGCCTTCTACTCGGCTGATA
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJIJJIJJJJJJJJJJJIJJJIJJJJJJJJJJJJIJJJJJJJJJHHFFDDEEDDDDDDEDDDDDDDDA
@9CT
GATCTAAGGAGATTACCTGGGGCAATTGATGTTATCGGTCAGACTATAACTATCAGCCGAGTAGAAGGCAGGCGACGGGCAAATGAGAACAGCAACATACA
+
@?@DDFFFFFHFFGGJHGHIFIJJIEDDGGGICHIJGIIIIJCEHIIJIIFGIGIIJJJIF@C>EHHF?DFCABDBDDD3<?AA4@@:ACA?8?C8<3@@C
@9CU
CGCCCATCTTGAGTCATAAGGCAGCTGTATGTTGCTGTTCTCATTTGCCCGTCGCCTGCCTTCTACTCGGCTGATAGTTATAGTCTGACCGATAACATCAA
+
;8:BB@BDFFBBBGEHFGIIHBDGEGB?EEFHHEEGGHICHC9DHG@@?FF@FGEHBDHIAADE@D7?;?C;=@CA6@C;@A@DDA>@CA889><@AC@@:
@9CV
TGGCAAATGAGAACAGCAACATACAGCTGCCTTATGACTCAAGATGGGAGTTTCCAAGAGATGGACTAGTGCTTGGTCGGGTCTTNTTTTGNNTTTNGNNN
+
@C@FFFFFGGHHGJIIJJJJJJJJIIJIGIJJJJIJIJJJIIIGGFIJGIGHIJJIIJJJIJIJJIJIIIJGIHHGHHFDD??##################
@9CW
GCCGAGTAGAAGGCAGGCGACGGGCAAATGAGAACAGCAACATACAGCTGCCTTATGACTCAAGATGGGAGTTTCCAAGAGATGGACTAGTGCTTGGTCGG
+
@@@F??ADDFHDHEFFGFHEEGHIFB=DHGB<FB9CCHID@GA>;?;7?3;@CBAC3;>ACD?C;ACABC?BCC:;>5:8<<CDDCCCCCCC@AAC?(:<B
@9CX
CAGCCGAGTAGAAGGCAGGCGACGGGCAAATGAGAACAGCAACATACAGCTGCCTTATGACTCAAGATGGGAGTTTCCAAGANATGTTTTTNTTNNNNNNN
+
@@@DDDFFDHF?FFG;BAFGGIIJIHFHIIAG=@FHGEGEHHGHECDEFEFCEEEEDDDCDDC;>CCCCCB<B<CCDCEDDD###################
@9CY
GCCGTTCCTTCAACCACCTTCCCAAACGCTCCAGACCCCAAGACCCGACCAAGCACTAGTCCATCTCTTGGAAACTCCCATCTTGAGTCATAAGGCAGCTG
+
@CCFDDDDHHFHGGIIIHIJIJIIGIIIIIIIJIJIIJIJJJIJIJJIJJEHHHFEDFDEEEEEEEDEDDDCCACDDDDDDDDDDCDACCDDDDDDDDDA@
@9CZ
GGGCAAATGAGAACAGCAACATACAGCTGCCTTATGACTCAAGATGGGAGTTTCCAAGAGATGGACTAGTGCTTGGTCGGGTCTTGGGGTCTGGAGCGTTT
+
@@CFFDDFHHHHAGHIIJIGHIGIIIJJJJJIJJIJIIGIGIJGGIIIGIDFFGHCEIEHIGGHIHIJJJDHEEEFEDFDD5;CCCDB@2=CCCCDDD@D@
@9D0
GCTGTTCCTTCAACCACCTTCCCAAACGCTCCAGACCCCAAGACCCGACCAAGCACTAGTCCATCTCTTGGAAACTCCCATCTTGAGTCATAAGGCAGCTG
+
?+=DD+A?DDDDDEIEIIICFEEIIICFIIDDEEEDIID;D=?)BCAAADADDDDDDDDDDDADAAAEAA>AAAA;AA??A?AAAA<>AA:B:::>???AA
@9D1
GGCAAATGAGAACAGCAACATACAGCTGCCTTATGACTCAAGATGGGAGTTTCCAAGAGATGGACTAGTGCTTGGTCGGGTCTTGGGGTCTGGAGCGTTTG
+
;;=DDDDADDHFFAEGG>?FEEEGBFBEHIEEG>CDDBGA9??BAHG;B8?BBFGHCAFGEHIG>F@9=ED@DEFEE>EC6;CCC@9;3;AA342959?9?
@9D2
AAGGCAGGCGACGGGCAAATGAGAACAGCAACATACAGCTGCCTTATGACTCAAGATGGGAGTTTCCAAGAGATGGACTAGTGCTTGGTCGGGTCTTGGGG
+
<<@A7DDD6DFFFFB@0?BD49DGBGFACF;=FEFFII>CF;DEFEEFB;?AA?BDDD@@9@?B>A;>@@?BBBBBBBBB?4:4@AA74@>BB2&9@A@B3
@9D3
AATGAGAACAGCAACATACAGCTGCCTTATGACTCAAGATGGGAGTTTCCAAGAGATGGACTAGTGCTTGGTCGGGTCTTGGGGTCTGGAGCGTTTGGGAA
+
@@@DFABDHHHGGJJBGIFHIHHGIIGEHEHIGJIJHIJJIIFHIIIJJIFBFCFEHIIIGBAGFHIIJIICC<<B6=CCA>B@8;CCD:<<9BDDBD###
@9D4
GCTTAATCCATAGGCTGTTCCTTCAACCACCTTCCCAAACGCTCCAGACCCCAAGACCCGACCAAGCACTAGTCCATCTCTTAGAAACTCCCATCTTGAGT
+
?;@DDDDBFB:CFE<?C3?E:?E>BH?8?A@CFFEIE??BD0;DG3?<6(.-<CFDF=@;::=?B@5;,;55>B(,5:>B@>(::>:5>@(83>?A>:444
@9D5
GCTTAATCCATAGGCTGTTCCTTCAACCACCTTCCCAAACGCTCCAGACCCCAAGACCCGACCAAGCACTAGTCCATCTCTTGGAAACTCCCATCTTGAGT
+
CCCFFFFFHGHHGJIJIJJJJJJJJIBIGIIGIIJJJJIJJJIJJJJJHIHIIGIJJIIJHHFDCEDBDDDDCDDDCDDDEDCC>CCDDCDDDCDCDDCDC
@9D6
GCTTAATCCATAGGCTGTTCCTTCAACCACCTTCCCAAACGCTCCAGACCCCAAGACCCGACCAAGCACTAGTCCATCTCTTGGAAACTCCCATCTTGAGT
+
@<@FFFFFHHGFFDHGIJGIGHHIIIHGIJJJJFHIJEIGIIIIGIIGHGDEGGIIIGIIEFF6?CDDDDDDADCCDDDDDDCCCDCCACCBDDCDDDCC4
@9D7
GCTTAATCCATAGGCTGTTCCTTCAACCACCTTCCCAAACGCTCCAGACCCCAAGACCCGACCAAGCACTAGTCCATCTCTTGGAAACTCCCATCTTGAGC
+
@@@DFFFDHHGGHGAHEEHGIFEBDHFGEFGCDFGEFF??FGEGECEGDGGCFHJIA;DBHHBB?E?=CCCCCCDD>CDCDCCDC>CDCC@BCDDCC::@#
@9D8
CGGCTTAATCCATAGGCTGTTCCTTCAACCACCTTCCCAAACGCTCCAGACCCCAAGACCCGACCAAGCACTAGTCCATCTCTTGGAAACTCCCATCTTGA
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJIJGIIJIJJJJJJIJJJJJJJJHIJJIIIIIIHHFFDDDDDDDDDDDDDDFDDDEDDDDDDDDDDDDDDDDDC
@9D9
TCGGCTTAATCCATAGGCTGTTCCTTCAACCACCTTCCCAAACGCTCCAGACCCCAAGACCCGACCAAGCACTAGTCCATCTCTTGGAAACTCCCATCTTG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJGIJIJJJIIHHJIJJIIJJJJJJJGHIIJJJIIHGHHFFDDDDDDDDDDDDCADDDDEDCCDDDDDDDDDDDDDC
@9DA
CAGGCGACGGGCAAATGAGAACAGCAACATACAGCTGCCTTATGACTCAAGATGGGAGTTTCCAAGAGATGGACTAGTGCTTGGTCGGGTCTTGGGGTCTG
+
?@<<7@ADAFADAHIGGFHBGHII>FGBGDB?FGGHG8B@CHGI4@HHDH;))7)(7;?)..6>(.(53;@CCCCC?@>CECC(+:9@<+09A########
@9DB
GCGACGGGCAAATGAGAACAGCAACATACAGCTGCCTTATGACTCAAGATGGGAGTTTCCAAGAGATGGACTAGTGCTTGGTCGGGTCTTGGGGTCTGGAG
+
@@@D?:DA?DAHDIBBD9?;C?F3D9@>GGGF>BBDDDDFE>FFCBFG9=.=EHI;A>?AHCEED;@@>;ACCC;@AAAC?3>?=B<-9@CCBB55<?C48
@9DC
TATCAGCCGAGTAGAAGGCAGGCGACGGGCAAATGAGAACAGCAACATACAGCTGCCTTATGACTCAAGATGGGAGTTTCCAAGAGATGGACTAGTGCTTG
+
CC@FFFFFHDDDFIGJIJIEHHAH<FGHI>HIIGIGGIIJIGGGEEFFFFCECEEEDDCDDDDDDDDCDCDDDDCD<CC@CDDDBBC>CD9CCCD:>>CAC
@9DD
GGGCAAATGAGAACAGCAACATACAGCTGCCTTATGACTCAAGATGGGAGTTTCCAAGAGATGGACTAGTGCTTGGTCGGGTNTTTTTTTTNTTNNTNNNN
+
@@CDDFFF?DHHHEHIIGIHGIJJIJJGIJIJIGCHGEIIIJIIJJGGGFFFDHIGHGCHIIED@FHGGHEHHHGHHFFDD####################
@9DE
GACAGGTTGGGACCGGCTTAATCCATAGGCTGTTCCTTCAACCACCTTCCCAAACGCTCCAGACCCCAAGACCCGACCAAGCACTAGTCCATCTCTTGGAA
+
@@@FDFBDDHDADEHIGJICDBCFEEGEHIJGDHGIJG>BD<FCEHGIJIJIGHIEBDFFFDECA??B=9A?<<=@BD@B8?<CCDCDCCCDC@CC>:>>C
@9DF
GCAACTTTCATGACAGGTTGGGACCGGCTTAATCCATAGGCTGTTCCTTCAACCACCTTGCCAAACGCTCCAGACCCCAAGACCCGACCAAGCACTAGTCC
+
@@@DBD?,2=DD?DFFHEFGHIADGHGDFGCGEGGGGIGE*BDFHGHEGHDHE@AEHCE)=AE@@D9<=3;@C(5<ADB?ABDDDBBDBBBA?BCCD>A:4
@9DG
CGGGCAAATGAGAACAGCAACATACAGCTGCCTTATGACTCAAGATGGGAGTTTCCAAGAGATGGACTAGTGCTTGGTCGGGTCTTGGGGTCTGGAGCGTT
+
@@@FDDFDHHGHHIIBEEGEHG@FGGGGIDGDGHHIGGGIIGIIG@DFEIGGGFGEBBCEHHIIGAEHD7AHHHEFFBBCCC;;?C>CBB3<CCCABC@0?
@9DH
GCAAATGAGAACAGCAACATACAGCTGCCTTATGACTCAAGATGGGAGTTTCCAAGAGATGGACTAGTGCTTGGTCGGGTCTTGGGGTCTGGAGCGTTTGG
+
@<<DBDDDF??AF>FE@DBFH9<AEA<EG@BFGGIIEGGC>D*9BBEG1*99??BD>FCGHEAAA7=@>EACAC)=ADB6;;@CC?;'8?A<:?99.<>@?
@9DI
GCAAATGAGAACAGCAACATACAGCTGCCTTATGACTCAAGATGGGAGTTTCCAAGAGATGGACTAGTGCTTGGTCGGGTCTTGGGGTCTGGAGCGTTTGG
+
@B@FFFFDHHHHFHIIFIJIIJJJICHIJEHIIIJJJJ<DF9DFHGIJGGFFGI*?BCGHJJGGIIJDGEHGI=?CEBDA>C@C>AB38<CC>8<<@@@BD
@9DJ
AATGAGAACAGCAACATACAGCTGCCTTATGACTCAAGATGGGAGTTTCCAAGAGATGGACTAGTGCTTGGTCGGGTCTTGGGGTCTGGAGCGTTTGGGAG
+
@@@FFFDDHHHGGIIEHIEBHGGGGFEGGEIGIJIJEHEGIIIDHFGGIIIIJCHJIIJIIIIIDGGIJIJDHEFF6=CCC<BB2;A?AAB?B5?<@@B?#
@9DK
TTCACTGCAACTTTCATGACAGGTTGGGACCGGCTTAATCCATAGGCTGTTCCTTCAACCACCTTCCCAAACGCTCCAGACCCCAAGACCCGACCAAGCAC
+
?@8ABAADHHHDDHGIGIGG<ABAE;AF?EA???D@*?8BFH>4BF9BF=..==FDGE4==;AEDD@C:>2(3;@@@CCC((9<B?8<33<9<BBB#####
@9DL
GCAAATGAGAACAGCAACATACAGCTGCCTTATGACTCAAGATGGGAGTTTCCAAGAGATGGACTAGTGCTTGGTCGGGTCTTGGGGTCTGGAGCGTTTGG
+
CCCFFFFFGFFHHJJIEHIIJIJJJJJJJIJFIJIJGIJJJEHIJJGIEGDFHIIIJIJJJJIHJGIHIIJJIGEAEED;?CCCC?B8;CCD>89>9?BBB
@9DM
GCCGAGTAGAAGGCAGGCGACGGGCAAATGAGAACAGCAACATACAGCTGCCTTATGACTCAAGATGGGAGTTTCCAAGAGATGGACTAGTGCTTGGTCGG
+
@@@FBDDAHFFHFIEIDGIIJIGEBGIJIGGHIEEFGIJIGJJHHHHGHFCDDFDEECECCDDDC<ADBABBDCECECA<AAA>CDDDDCCDCDC@BCCDD
@9DN
CTTCACTGCAACTTTCATGACAGGTTGGGACCGGCTTAATCCATAGGCTGTTCCTTCAACCACCTTCCCAAACGCTCCAGACCCCAAGACCCGACCAAGCA
+
?8=?DD;DDFF?BDGIEICHGHFD<AAECBEAGBG0@3??BBD>F<BB8CA@@@CDA>=7?((5?@?DB3>>('3=?8>:555<<7?<8(9?>35<<?BB2
@9DO
GTTTTAGCATCTTCACTGCAACTTTCATTACAGGTTGGGACCGGCTTAATCTATAGGCTGTTCCTTCAACCACCTTCCCAAACGCTCCAGACCCCAAGACC
+
::8+A?D+2=2A,:2:<E3:F+:AF><E,AAEE9?<E6DABB?@ADDECCB7@AA;C>=C@AA)=?A>.)6(51>A35;>>>;??################
@9DP
TCAGCCGAGTAGAAGGCAGGCGACGGGCAAATGAGAACAGCAACATACAGCTGCCTTATGACTCAAGATGGGAGTTTCCAAGAGATGGACTAGTGCTTGGT
+
CCCFFFFFHFHHHJIJJJJIGIFIIJJJJJIIIIJIJGJGGHHHGFEFFFEEECCEDCCDDDCDCDDDDDDBCD<ACDDEDDDDDDDDACDDDCDDEDCD4
@9DQ
GTTTTAGCATCTTCACTGCAACTTTCATGACAGGTTGGGACCGGCTTAATCCATAGGCTGTTTCTTCAACCACCTTCCCAAACGCTTCAGACCCCAAGACC
+
@@<B?D?DHHHHDHAAGFAHEEDHBEDFDHIGGG*C;DBE@G>FHII9FFH=CG:=EDEH@E7?AA3;@;61;=A>>;?######################
@9DR
GTTTTAGCATCTTCACTGCAACTTTCATGACAGGGTGGGACCGGCTTAATCCATAGGCTGTTCCTTCAACCACCTTCCCAAACGCTCCAGACCCCAAGACC
+
;:;BD=AD8DFBDIID4<<++<AFH:<C3+2AC8)1)0?)?F66'74./@;8@==DEFE>C=;;?DD3);;=(555>B=:(,(',55@BBA##########
@9DS
CGACGGGCAAATGAGAACAGCAACATACAGCTGCCTTATGACTCAAGATGGGAGTTTCCAAGAGATGGACTAGTGCTTGGTCGGGTCTTGGGGTCTGGACG
+
CCCFFFFFHHHHHJJJIIJJIHIGIIJIIIIHJJJJJJJJJJIJIIJJJJFHHIFDHIIJJHHHHHFFFFFEECEEEDCB>CDDD<<CDDDDD5>CCC###
@9DT
CAAATGAGAACAGCAACATACAGCTGCCTTATGACTCAAGATGGGAGTTTCCAAGAGATGGACTAGTGCTTGGTCGGGTCTTGGGGTCTGGAGCGTTTGGG
+
CC@FFFFFHHHHFIJIIIFFGIGJIDGIIIEHIIIIJJIHEHIDIBFIEB9BFIIJJHJIIHHC>GHIIJJJGHFGFDDACDDDDB?BCDDDBCD>BBBD>
@9DU
AGAAGGCAGGCGACGGGCAAATGAGAACAGCAACATACAGCTGCCTTATGACTCAAGATGGGAGTTTCCAAGAGATGGACTAGTGCTTGGTCGGGTCTTGG
+
BCCFDF?DHFHHGJJJJGJJIGGIGGGE>HGGHFHIJI;=GAG@H>EEHHBEDEFFFDC@C@@@5>AAAACC@BC@CCAAC>9>CCDACB>@@B@25<@>@
@9DV
GTGGGTTTTAGCATCTTCACTGCAACTTTCATGACAGGTTGGGACCGGCTTAATCCATAGGCTGTTCCTTCAACCACCTTCCCAAACGCTCCAGACCCCAA
+
@==DD@DDHHB?DFDEHIIIIGII>CDHGIIIIIIIIGBGHEIC;BGGGGAGHGICED>EH:?@BC@DC@@AAA@BBBBA?CCCCBB?B@BBCCCBBBBB@
@9DW
GCGACGNGCAAATGAGAACAGCAACATACAGCTGCCTTATGACTCAAGATGGGAGTTTCCAAGAGATGGACTAGTGCTTGGTCGGGTCTTGGGGTCTGGAG
+
???ADD#2<?DBDEEE4CFBC>EEI?EEEDA@DD*?BBD4BDBDD<?DA?)8;.;CCE<DEEDCDDDDCDADAA7?AAAA@AA?==9??A>><99;>?<>8
@9DX
GCGACGGGCAAATGAGAACAGCAACATACAGCTGCCTTATGACTCAAGATGGGAGTTTCCAAGAGATGGACTAGTGCTTGGTCGGGTCTTGGGGTCTGGAG
+
@C@@DDFFHHH;FHCHHEEAGEHGGIIGGGGIHIIIEHICGGIFHIIICHFFHCHHHFHFGHFFEFC@CC@@ACCCDEDDDCDDDD<9<CC>BD09?CDCB
@9DY
TAGGCCGTGGGTTTTAGCATCTTCACTGCAACTTTCATGACAGGTTGGGACCGGCTTAATCCATAGGCTGTTCCTTCAACCACCTTCCCAAACGCTCCAGA
+
<@@DDDDDFFFDFIIGFG4CHIII@GHEEDG9?FHHGGEHIEGG?DGHGCGHEGEBE:BDCA>A@:>;;=;@C:5>5:>C<@B@@:?>?+98?<B?&9@>>
@9DZ
CTGGATCTGGCCGTGGGTTTTAGCATCTTCACTGCAACTTTCATGACAGGTTGGGACCGGCTTAATCCATATGCTGTTCCTTCAACCACCTTCCCAAACGC
+
@?@B7BDDF>DFFEGI<EHDFGFGD9??DHGBGG>GADBBBF9009989;.88ABHCEAEDFAEC3@AC5>AC:5,,5>A:A(5(5?8?08A#########
@9E0
GTTTTTCACTGGATCTGGCCGTGGGTTTTAGCATCTTCACTGCAACTTTCATGACAGGTTGGGACCGGCTTAATCCATAGGCTGTTCCTTCAACCACCTTC
+
@@@DDDEDDDBF:BFBGGCEFEGGG?EGAHGGIEGGGHCGGAHGGFFEEHD@HGHGIE=CDHHGGHDAA@?@C;>CCCCCCCA92:ACCCAAC>828?2@C
@9E1
CTTGTTTTTCACTGGATCTGGCCGTGGGTTTTAGCATCTTCACTGCAACTTTCATGACAGGTTGGGACCGGCTTAATCCATAGGCTGTTCCTTCAACCACC
+
=+=DD;DBDFDD,A?+A3AA4C>@@@FE))10:D4?D9<F?*9?DEIE<;)/=)=C:@38(.===8A?='',38@3;>A::AA:A:2<>@@BA@(44<<?0
@9E2
ATCGGTCAGACTATAACTATCAGCCGAGTAGAAGGCAGGCGACGGGCAAATGAGAACAGCAACATACAGCTGCCTTATGACTCAAGATGGGAGTTTCCAAG
+
@@CFFFFFHHHHHIIIIIIJJJJIJIBHEHGIJJFEHIJIGIDHIHBBEDDCEDCEACC?CCBDCCCDDDCCCBCDDDCCDDD@CCCCCCBCB2?CACDCA
@9E3
CCGAGTAGAAGGCAGGCGACGGGCAAATGAGAACAGCAACATACAGCTGCCTTATGACTCAAGATGGGAGTTTCCAAGAGATNNNNNNNNNNANNNNNNNN
+
@CCFDDDFGHHGHIIJIJGIIIGBIJIJJJJIIIIJGJJIIIIJJJGHHGEFFFFFFECEEEDDDDDDDD@DDECEDDDDCC###################
@9E4
GCGACGGGCAAATGAGAACAGCAACATACAGCTGCCTTATGACTCAAGATGGGAGTTTCCAAGAGATGGACTAGTGCTTGGTCGGTTCTTGGGGTCTGGAG
+
@C@FDF@DDFHDHECGIIJJCBGBCGGIJIIJIIJJJIIIIGIGGEHHGGFCEHGHGFHH37@DDBCC@@CCADDDCDDCDDDBD))8>AA3<@5>CDDAB
@9E5
GCGACGGGCAAATGAGAACAGCAACATACAGCTGCCTTATGACTCAAGATGGGAGTTTCCAAGAGATGGACTAGTGCTTGGTCGGGTCTTGGGGTCTGGAG
+
@@<DDDDDFA??9C@C@EGGG9??)?;FEGHBFCFHGIIGGIGCF@;==F@@D=DEHEH3???;BEA>CACCCC@@@@CA?5>BBBB<?C:@BB59C?CC@
@9E6
CAAATGAGAACAGCAACATACAGCTGCCTTATGACTCAAGATGGGAGTTTCCAAGAGATGGACTAGTGCTTGGTCGGGTCTTGGGGTCTGGAGCGTTTGGG
+
CCCFFFFFHHHHHJIJJIJJJJJJIJJJJJJJJJJJJIIJHIIJJIJFHIIIIIIHIGIJJIIIIIFHIIJJGEHHFDADDDDDDD?BCCCABDDDDDDD<
@9E7
GTCATTATCTTCAGTTCAGACATGAGAGCTTGTTTTTCACTGGATCTGGCCGTGGGTTTTAGCATCTTCACTGCAACTTTCATGACAGGTTGGGACCGGCT
+
;8=AD>DDFFHHDI?FGFEGEHE:A<CG=F?GB9CG)CGFB<B9BFBF>BB@7@A6-5CFHA)=@@?AACHHC@C;;@A@C>@CCCC@@;A##########
@9E8
GAGTCATTATCTTCAGTTCAGACATGAGAGCTTGTTTTTCACTGGATCTGGCCGTGGGTTTTAGCATCTTCACTGCAACTTTCATGACAGGTTGGGACCGG
+
C@CDFFFFHGHHHJGJIJJIJIIJJIIJJJJIGHEHIJJIIJJCBHHIJIFHIJJGIJ@FHIBGIIGHGGHHHFEFFFEEEEDCECCCCCB@C<=B9<@B@
@9E9
CAGGTGAGTCATTATCTTCAGTTCAGACATGAGAGCTTGTTTTTCACTGGATCTGGCCGTGGGTTTTAGCATCTTCACTGCAACTTTCAGGACAGGTTGGG
+
@@@ABDDDCFBDFDGEEGBHIJGIIJGE?BEGC@B)?FE1?DDGHICGEGBGHG@FBHGHGFI8;@?>ACEFDD;@33>;CE>AC@@##############
@9EA
GGCAAATGAGAACAGCAACATACAGCTGCCTTATGACTCAAGATGGGAGTTTCCAAGAGATGGACTAGTGCTTGGTCGGGTCNTGGGNGGNNNNNNNNNNN
+
<@@DFDFFBHDFHJI9EFEHIJJJJJIJGJJJJJGGIJJJJJJGIJ29DD8?FFIJI;FHJIIIJJIJJJGGIHFAEEFD??###################
@9EB
GGCAAATGAGAACAGCAACATACAGCTGCCTTATGACTCAAGATGGGAGTTTCCAAGAGATGGACTAGTGCTTGGTCGGGTCTTGGGGTCTGGAGCGTTTG
+
CCCFFFFFHFHHHJJIJJJJJJJJIJJJJIJJIJJJJJJJIJGIIEGIJGHGGIJJGIJJJJIIGIJGEHGGIHGEEDBDCDDCCCBB=?CDDDDDD>?BD
@9EC
TGTGGCCCCAGGTGAGTCATTATCTTCAGTTCAGACATGAGAGCTTGTTTTTCACTGGATCTGGCCGTGGGTTTTAGCATCTTCACTGCAACTTTCATGAC
+
@@@DD?DBFBFF:C+:2A?FHEB>DFHIIEFFCA4CGGFDC9FCGECFF@?FEF@FA8BD:@CC:@EE=BD?1=@ACCBBBBBDDAB@(55:>@BAADA<4
@9ED
GCGACGGGCAAATGAGAACAGCAACATACAGCTGCCTTATGACTCAAGATGGGAGTTTCCAAGAGATGGACTAGTGCTTGGTCGGGTCTTGGGGTCTGGAG
+
@@@FFDFDAHFFFIIGGGAHIEIJJGGFHGEGEHEGGIGHGIJIJ@@C=C@FGHEEEEEFHHFFFDE@CCCCCDCCCDDDDCCDDB<>CAC@BB55?A?##
@9EE
TTACAATGTTCAAATGTGGCCCCAGGTGAGTCATTATCTTCAGTTCAGACATGAGAGCTTGTTTTTCACTGGATCTGGCCGTGGGTTTTAGCATCTTCACT
+
C@CFFFFFHHHGHGJHGHIJIIIHGIGIFICFHIIJJIJJJJJIIIIJIIIIIIIHHIIJIIJJIIIGEGHIIIIFHHHHEDDDD@BDDD?CADDDDEED>
@9EF
CGACGGGCAAATGAGAACAGCAACATACAGCTGCCTTATGACTCAAGATGGGAGTTTCCAAGAGATGGACTAGTGCTTGGTCGGGTCTTGGGGTCTGGAGC
+
@@@DDDDDADFFFG@4E<FCDFDHF??DHCHG>GIIICDGGIIEEGGGHIGGGIIIHIIEGE?EEHED@C@>(>ACC@@=ACBB:99?@CC?9&)9AC:89
@9EG
GCAAGTTTACAATGTTCAAATGTGGCCCCAGGTGAGTCATTATCTTCAGTTCAGACATGAGAGCTTGTTTTTCACTGGATCTGGCCGTGGGTTTTAGCATC
+
@CCFFDFDHFHFHBGGGIFIGBAIHDGGGGCG*?EE<DGGIGB<BFGIJF9?BGCB;FFEDFHJDGI6CFIEE>D@AEA=A>DB@>A8>??8?@#######
@9EH
GCAGGCGACGGGCAAATGAGAACAGCAACATACAGCTGCCTTATGACTCAAGATGGGAGTTTCCAAGAGATGGACTAGTGCTTGGTCGGGTCTTGGGGTCT
+
;??1A@DDDDDDDDBB@@@D99B3B)B@>@>?DCAC===A7@DEEEA@CEADADDA?)((6;>A@3;=?=>AA5:5::((:>AA#################
@9EI
CAGGCTCCCAGCAAGTTTACAATGTTCAAATGTGCCCCCAGGTGAGTCATTATCTTCAGTTCAGACATGAGAGCTTGTTTTTCACTGGATCTGGCCGTGGG
+
@<<DADBDB>?D8BF2A<CH@EHAEH9CHHG?C?*1??C@DG0*?F?<DH9BFHG:C<8)=.BFII;7=;=C>D7?E(7).5);>@>@@;@C#########
@9EJ
CCTGACTTCGTGCAGGCTCCCAGCAAGTTTACAATGTTCAAATGTGGCCCCAGGTGAGTCATTATCTTCAGTTCAGACATGAGAGCTTGTTTTTCACTGGA
+
??<??DDD,=2:+++<@3<CE3<+<)?*11****?1*?<??B?***08?D7(7(.=46@D:@=7=CEI;77CDD###########################
@9EK
GGCAAATGAGAACAGCAACATACAGCTGCCTTATGACTCAAGATGGGAGTTTCCAAGAGATGGACTAGTGCTTGGTCGGGTCTTGGGGTCTGGAGCGTTTG
+
;:=BBDDDB?FDD:AEFEGIFHGI<CA<FGEEF@<?D>F>CBCFAGDEF0/9?F@?F@>BBC=C8C@==CAEE>E..4?C;>=>@((,,,<5(><?5@BBB
@9EL
GGCAAATGAGAACAGCAACATACAGCTGCCTTATGACTCAAGATGGGAGTTTCCAAGAGATGGACTAGTGCTTGGTCGGGTCTTGGGGTCTGGAGCGTTTG
+
8;:?D+BDDCCF><ACFFBCGEFB<AF?@F@FD<9<D?GECC?B?F=BG?BFFEEEIBF8<;DECG>C=@>@CE?.79BC6>=>A@BB3;<??+89<<09?
@9EM
TATCAGCCGAGTAGAAGGCAGGCGACGGGCAAATGAGAACAGCAACATACAGCTGCCTTATGACTCAAGATGGGAGTTTCCAAGAAAAGGGGAGNNNNNNN
+
@CCFFFFFHAHFHGIJJJJIJIIIGIJJJJJIIIJIGIIJIDHHHHFFFFFEEEDDDDDDDDDDDDDDDDDDDDCD?CDEDEA##################
@9EN
CAGCAATACTCTGTGATGATGTAAATGGGGCCTGACTTGGTGCAGGCTCCCAGCAAGTTTACAATGTTCAAATGTGGCCCCAGTTGAGTCATTATCTTCAG
+
=<==AAAAA4<A?,<7<<==>,3?=<==<+@?;A3?<?BB4?=?0:=;A<AB=5>>A<BA7=;=>=7)77=>3AAAAA>@#####################
@9EO
CATAGAAGCAATACTCTGTGATGATGTAAATGGGGCCTGACTTGGTGCAGGCTCCCAGCAAGTTTACAATGTTCAAATGTGGCCCCAGGGGAGTCATTATC
+
C@CFFFFDFHBH>EEHIIHHIHIJIJHGIJIJGIIHIGGGDGCCCBDEGHDECDGGIIBFGFFDE>@GAHGEF@ECEEC;@BDCA>CB<'38=5?(:AD>:
@9EP
CTGGGTGGTGGCTCAGGAAGCTATCCCTATTCTTATGCAAATAGTTGACCAAATCTCCATAGAAGCAATACTCTGTGATGATGTAAATGGGGCCTGACTTG
+
CCCFFDDFHHHHHJJJJJJJIJBGIJJIJJJJJJJJIJJJJJJJJJJJJJFHIJJJJJJJIJJJJJIJJHHHHHHFFFFFFFFFEFEFEDBDDDDDDDDDD
@9EQ
GCCGAGTAGAAGGCAGGCGCCGGGCAAATGAGAACAGCAAAATACAGCTGCCTTATGACTCAAGATGGGAGTTTCCATGAGATGGACTAGTGCTTGGTCGG
+
;;?DD:BAA,<DD+<CE:F)?0::6?/BDA@4)B37)8@@))=;@DDCDA?;).7;>>:>A>5;;>A##################################
@9ER
CGACGGGCAAATGAGAACAGCAACATACAGCTGCCTTATGACTCAAGATGGGAGTTTCCAAGAGATGGACTAGTGCTTGGTCGGGTCTTGGGGTCTGGAGC
+
@<?DDFFFFHHGHJGIJIJIJJCHHIJJJGGIJJIJIJIFHIJIJIJ<FHGHGGCE@EDHG<(.7AD=9BDEECDCC3@?>A;2=,59@@CAD&039?:?#
@9ES
GGGCAAATGAGAACAGCAACATACAGCTGCCTTATGACTCAAGATGGGAGTTTCCAAGAGATGGACTAGTGCTTGGTCGGGTCTTGGGGTCTGGAGCGTTT
+
CCCFFFFFHHHGGIIIIJJGIIJIJJIIGIJIGHGIIIGIIIIDFIHIIIHGIHJIIIIGHGGGHICGGDGIGGHGCDFCD??CCDCBD;?C?CCB?@5?0
@9ET
GGGCAAATGAGAACAGCAACATACAGCTGCCTTATGACTCAAGATGGGAGTTTCCAAGAGATGGACTAGTGCTTGGTCGGGTCTTGGGGTCTGGAGCGTTT
+
CCCFFDDFHHFD?DHJJIIHIGGHIIIIFGJGGIIJGIGIJFIEGIFF<FGBFGEGB@FHEFHGCDGGHDDGHA?E?CE/8,35;@CAB88<?CAA39<B#
@9EU
GGCTGTTCCTTCAACCACCTTCCCAAACGCTCCAGACCCCAAGACCCGACCAAGCACTAGTCCATCTCTTGGAAACTCCCATCTTTTTTNNNTNNNNNNNN
+
CCCFFFFFHGHHHJJJIJIIIJJJJIJJJIIJIJIIJJIIGIGGIGHIJJGGHHGHFFFFFEEEEEEEEDCCCDDDDDDDDDD>A;@@#############
@9EV
CTCCATAGAAGCAATACTCTGTGATGATGTAAATGGGGCCTGACTTGGTGCAGGCTCCCAGCAAGTTTACAATGTTCAAATGTNGGGNGTNNNNNNNNNNN
+
?@@DDDADDFHDHHDEH@EFFEBA@EFHI<ECBD>E))?DFFHIIIGEHC9<<D(9;;BCECACE7CDHIEA>>.==;@DDD###################
@9EW
TGCCCTTCCATCTACAAAAGCTGAGTTTACTTCTCCTCCTTCTTTGTTCAAGACTGGGCTTCCACCGAGCAGAAACAGCACTTCTTTNTGTAACGCGNNNG
+
@@@FFDDDFHBHDFHIIIIGHIIDF?ABHHE?EFHGGGGEHAHHIG?BBHBFGHIGIDE@FGHIIIIGIFFHFFCFD;;@@CA;>>C##############
@9EX
TTCCAGCTCTTTCTTTGGCTTCTCTGGGTGGTGGCTCAGGAAGCTATCCCTATTCTTATGCAAATAGTTGACCAAATCTCCATNNNNNNNGNNNNNNNANN
+
@C@FFFFFGHHDHJIJJIJJJ@FFCFHG<C@??DG8??FF?GGBHGGEGG=BCFHI@;@FIIIGGDG;C;??EHED;;@DE@C##################
@9EY
TGGATCTGGCCGTGGGTTTTAGCATCTTCACTGCAACTTTCATGACAGGTTGGGACCGGCTTAATCCATAGGCTGTTCCTTCAACCCCCGGGNNNNNNNNN
+
@CCFFFFFHGHHHJIJIJJJIJJIJJJIIGJIJIJJJJJIJIJJFJJJD<BFIIIIIJHFFDEEECECCDDDDDDDD@CDDCCCC################
@9EZ
CCCAAACGCTCCAGAACCCAAGACCCGACCAAGCACTAGTCCATCTCTTGGAAACTCCCATCTTGAGTCATAAGGCAGCTGTATGGGGGGGGGNNNNNNNG
+
==7=7<A)0<CCB<=+2AAACB31:@?):A<AA19)938==A7>BABBBAA>7>BAAA==>>@@?@@@@>@##############################
@9F0
TGTGCTTTCATCAGCAGGGTTCAATCCAAAGATATCCAGCTCTTTCTTTGGCTTCTCTGGGTGGTGGCTCAGGAAGCTATCCCTATAAGANTNNNNNNNNN
+
@@@DDDDDFFFFFEF<FEG:AEHIHEFDFHFFIEFF<GEADGEFIIIEIFB<F>@FFEIFF;@A;EE@>AEEE>@?BCCA>ABA#################
@9F1
CTGGTGCTGATCTTTCTGATTATTTTAATTATGGGTTTAATGAAGATACCTGGAAAGCTTACTGTGAAAAACAAAAGAGGATACGGGGGGGGGGGGNNNTN
+
@@CFBDFFGHFGHJJJJIIIJHHJJI@FGGIGIJJAFHIIJIEHIJIJJJGHIIGIJJIJJJJJGIJGJJIIIIJJJFHHHFFD#################
@9F2
TGGGACTTGAAGTTATACCAGTAACCTCTACTACAAATAAAATTACGGCCGAAGACTGTACTATGGAAGTTACACCAGGTGCNNNNNNNNNNNNNNNNNNN
+
CCCFFFFFHGGHHIIGJJJJJFFHJJIJIIJIIIJIGIIIJIHGJJIIFIDBGIIIGGCHGJIHFGGHHFFECDFEDDB>C####################
@9F3
ACCACCTTCCCAAACGCTCCAGACCCCAAGACCCGACCAAGCACTAGTCCATCTCTTGGAAACTCCCATCTTGAGTCATAAGNNNNNNNNNNNNNNNNNNN
+
?=?DDDDEHHHHHIJIIJJJIJJIGIJJJGJJIIJFJJJJJJJJIJJJIGCCEHHHHHFFFFFEE>AEDDDDD@CCCCDDCD###################
@9F4
CTGTTCCTTCAACCACCTTCCCAAACGCTCCAGACCCCAAGACCCGACCAAGCACTAGTCCATCTCTTGAAAACTCCCATCTTNNNNNNNNNNNNNNNNNN
+
CCCFFFFFHHHGHIJJIJJJJJGIIIIJIJJIIJJIJJJJJJJIIJJFIIGHHFHHFFEEFFFEEEEEE(>CDDDDDDDDDDD##################
@9F5
TTGGAAACTCCCATCTTGAGTCATAAGGCAGCTGTATGTTGCTGTTCTCATTTGCCCGTCGCCTGCCTTCTACTCGGCTGATNNNGNNNAAANNNNNGGGG
+
CCCFFFFFHHHHHJJJJJIJHHJIJJJJIJJIJJHIHIIIJJJJ9BGIIIGIJJIJJJJJJJIJJJJHHHHHHHFFFDDDBC###################
@9F6
CAAATGTGGCCCCAGGTGAGTCATTATCTTCAGTTCAGACATGAGAGCTTGTTTTTCACTGGATCTGGCCGTGGGTTTTAGCNNNANNNNAANNNNNGGGG
+
CCCFFFDFHHHHHGGIFHIIFHIIFGIIIJJJJJJJJJIJJIIGHIJIJIBFHIJJJJJJIIJJJJJJIJJEHFF>ADDDDA###################
@9F7
GTGGGTTTTAGCATCTTCACTGCAACTTTCATGACAGGTTGGGACCGGCTTAATCCATAGGCTGTTCCTTCAACCACCTTCCANNNCACACCNAANAACGG
+
C@BFFDDFHHHHHJJJJIJJJJJJJJIIJIIJJJJJJJGHGJJJGIJJIJAGGIGIJJFHHHHFFFDFFC@@C>ADBBBC:A###################
@9F8
CCTTCAACCACCTTCCCAAACGCTCCAGACCCCAAGACCCGACCAAGCACTAGTCCATCTCTTGGAAACTCCCATCTTGAGTNNNNNNNNNNNNNNNNNNN
+
@CCFFFEBDHHHGIJIJGGIGIIGIGGIJIJIGIJJIGGIJIIGIHCCHGEHFCEDDEFFFFEEDDCEDDDDDDDDDDDDDD###################
@9F9
CGGGTTTTAGCATCTTCACTGCAACTTTCATGACAGGTTGGGACCGGCTTAATCCATAGGCTGTTCCTTCAACCACCTTCCCNNNNNNANNNNNNNNNNNN
+
@@@DDDDDDBHF?GIGBBHCGHFI@GIII@HH@GGHH?C@DFEHEFH@@@@FEHHIHICFEEH?3;CDDDCC;A?B?@CCCC###################
@9FA
CCCAGGTGAGTCATTATCTTCAGTTCAGACATGAGAGCTTGTTTTTCACTGGATCTGGCCGTGGGTTTTAGCATCTTCACTGNNNNNNGGNNNNNNNNNNN
+
@@CFDFDEFD:AFADHGGFBHIEFGHIIHEDHGIGE??CBHADDFG@GIGGGA@DGHGGBH@AF/5?EAEHCDCEE@;CCC####################
@9FB
GTCGGCTTAATCCATAGGCTGTTCCTTCAACCACCTTCCCAAACGCTCCAGACCCCAAGACCCGACCAAGCACTAGTCCATCNNNNNNAGNNNNNNNNNNN
+
@@@FFFFFHHHHHJJJJJGIIIJIIJJJIJJIJJJJJIJJGIJIIIIIJIGIJJJJJIIHHFHFFDDBDDDDDDDDCDDCEC###################
@9FC
CGGCTTAATCCATAGGCTGTTCCTTCAACCACCTTCCCAAACGCTCCAGACCCCAAGACCCGACCAAGCACTAGTCCATCTCTTGGGGNNNNNNNNNNNNN
+
@@@BDAFFDFDHHAE?FGHHIHC@HGGIBE=G?EDDGGDGHIGIGHIIIEGGFHGGIIIECEEFCCCB=?CCCC>CCCDCCCD>@CB##############
@9FD
CTTCACTGCAACTTTCATGACAGGTTGGGACCGGCTTAATCCATAGGCTGTTCCTTCAACCACCTTCCCAAACGCTCCAGACCCCGCCAACNGTNNNNNNN
+
CCCFFFFFHHHHHJJJFIJJJJJIHGHEGIGIIJIIJIJIIGGIJJJJIJJHIJJIJIIEEHFGDEEFFEEC@BDDDDDDCBD##################
@9FE
CTTCCCAAACGCTCCAGACACCAAGACCCGACCAAGCACTAGTCCGTCTCTTGGAAACTCCCATCTTGAGTCATAAGGCAGCTGTATGTTGCTGTTCTCAT
+
??;+A+BDAA@1AEEAD9A+9A+?8;:CDD@D:08B6BB=B8.=A(.(.7==?97)..;?;?AA@6>AAA>>;;;AAA>9<?>>((,4>DAAAAA3>A>3>
@9FF
TATCAGCCGAGTAGAAGGCAGGCGACGGGCAAATGAGAACAGCAACATACAGCTGCCTTATGACTCAAGATGGGAGTTTCCAAGAGATGGACTAGTGCTTG
+
??@DDDD8FFH+AFHEIIGCEIDGAGFHI0AHGGGCD@GGHHFCEEBDDB>;ACCCBCFCCCACCCCCC@@CC?382>A>CCCCA<<>AC((49?@:@@@>
@9FG
GCGACGGGCAAATGAGAACAGCAACATACAGCTGCCTTATGACTCAAGATGGGAGTTTCCAAGAGATGGACTAGTGCTTGGTCGGGTCTTGGGGTCTGGAG
+
@@CFFFFFAFHHHJJEIIHIIGGIGGGHGGCGEGGGCEHIIIGGGGGHEGGGI@H;EFEHFFFBEECECCEC>C@CC@CDDDDBDB89?C>>?BBDCCD>A
@9FH
CTTCAACCACCTTCCCAAACGCTCCAGACCCCAAGACCCGACCAAGCACTAGTCCATCTCTTGGAAACTCCCATCTTGAGTCATAAGGCAGCTGTATGTTG
+
>==A17+2?<AA@AAABBBBAAA=?>A@AB=AAA=;ABBAAA';=>;AB>7>>AA?>>@;@?@@>@>>=?;5;;=????>599=:>???;=99==38??;:
@9FI
GCGACGGGCAAATGAGAACAGCAACATACAGCTGCCTTATGACTCAAGATGGGAGTTTCCAAGAGATGGACTAGTGCTTGGTCGGGTCTTGGGGTCTGGAG
+
<B?58@:;>DEDDCDDDCDDCDEDDEEEECDFDFGHHGHGHHJIGIIIGFGJJJIIGIIIIIHGGGGHEFHGIJGGEIIHEGIIIIIJHHHHFFFFFFCCC
@9FJ
GCAAATGAGAACAGCAACATACAGCTGCCTTATGACTCAAGATGGGAGTTTCCAAGAGATGGACTAGTGCTTGGTCGGGTCTTGGGGTCTGGAGCGA
+
CCC;@ACC>>CCCACCB>CACA?DDAA@D<FDFHHHFHEIGGIGHGCIGHC9BAJIIGGGHEIGGJHH<GGIIGEJIHFFEIHIDHFDGFDDDB@;@
@9FK
TGCCCTTCCATCTACAAAAGCTGAGTTTACTTCTCCTCCTTCTTTGTTCAAGACTGGGCTTCCACCGAGGCGAAACAGCACTTCGTCTCCGTCTCAGACAA
+
1?<;ADD+22AC<42<?<<<AEF9?9+2ACE>ECE<C>D>C?DDB<?@DE9??0?88(?;@B@=@####################################
@9FL
CTCCAGACCCCAAGACCCGACCAAGCACTAGTCCATCTCTTGGAAACTCCCATCTTGAGTCATAAGGCAGCTGTATGTTGCTGTTCTCATTTGCCCGTCGC
+
??@DDDDD??DHHHHBGH>BG1:C@AGGF<FFHDHIIIGIEDCIAE;CFDF;FGEGHIICEHHEHCEDD=ACC;;AC;@CCCCFCCEC>AADCCC>BBBB<
@9FM
GTTCCTTCAACCACATTCCCAAACGCTCCAGACCCCAAGACCCGACCAAGCACTAGTCCATCTCTTGGAAACTCCCATCTTGAGTCATAAGGCAGCTGTAT
+
===;?2AABBA3==+242>@BBA+71+@:BB?;30?=)=9>>(0744'=A<B>AAAA9>??>;>>;;56;=;--(59>=:?9;9595:9(888909=??:8
@9FN
GGAGATTACCTGGGGCAATTGATGTTATCGGTCAGACTATAACTATCAGCCGAGTAGAAGGCAGGCGACGGGCAAATGAGAACAGCAACATACAGCTGCCT
+
CCCFFFFFHHHHHIJJJJJJJIJIJJJJJJJHIJJJJJJJJJJIIJIJJJGIHGFGGHIJJAEHHFFCDDDDDDDDCDDDDDCDDDDDDDD@:@>>C@CBC
@9FO
GGCAAATGAGAACAGCAACATACAGCTGCCTTATGACTCAAGATGGGAGTTTCCAAGAGATGGACTAGTGCTTGGTCGGGTCTTGGGGTCTGGAGCGTTTG
+
CCCFFFFFHHHGHJJIJIJJJJJJJJJJJJGJJJJIJJIJJJIIJJJGIIBFIJJIIHIJJJJJJJIIIGIJJGHHHFFDABDCDDBDBDCDCCDDDBDDB
@9FP
CTTCAACCACCTTCCCAAACGCTCCAGACCCCAAGACCCGACCAAGCACTAGTCCATCTCTTGGAAACTCCCATCTTGAGTCATAAGGCAGCTGTATGTTG
+
CC@FFDFFAABFFHEHII>@AHGIIGBCDGCHCHIIGGII>A@6;CAGGC=??EHFEDFFFD<;@;@>CCCBCCCCCA:@>@CCDCCCCCCBCC:ACD:@:
@9FQ
CTCCAGACCCCAAGACCCGACCAAGCACTAGTCCATCTCTTGGAAACTCCCATCTTGAGTCATAAGGCAGCTGTATGTTGCTGTTCTCATTTGCCCGTCG
+
A:<93)&<<:C@90(836;51@@>6>;@C??7;;:AAEA4D>@4=-F@EGGGEFFGF@>GGIGGEGHDB?@ECIGIIGGCEIGHHFBHHAFF?DDAD<@@
@9FR
GGCAAATGAGAACAGCAACATACAGCTGCCTTATGACTCAAGATGGGAGTTTCCAAGAGATGGACTAGTGCTTGGTCGGGTCTTGGGGTCTGGAGCGTTTG
+
11=<<@42?@B8@7?>@B=+++33?@CBBA>@@A==74<7?<47*78=1;/>=?ABB>BAAA;>B=>B=;)==>AAA6@@;/;;?9==:====?#######
@9FS
CCCGACCAAGCACTAGTCCATCTCTTGGAAACTCCCATCTTGAGTCATAAGGCAGCTGTATGTTGCTGTTCTCATTTGCCCGTCGCCTGCCTTCTACTCGG
+
@@@FFFFFHHGHHJGHCGEHGIJJJJIGHGIJJJIGIIJIJJGIHGGIGIF>DHGHEICFGJJJJJJGIHHHHHHHGFFBDBAABDDBD?BDDCCDCDDD<
@9FT
TGCTCCTTCAACCACCTTCCCAAACGCTCCAGACCCCAAGACCCGACCAAGCACTAGTCCATCTCTTGGAAACTCCCATCTTGAGTCATAAGGCAGCTGTA
+
@?<DDEFFGHGDFBGFFHHIGIII=FEGI>AFG;FHHGEHIBGIGGGHHC?AHHG@CED:@ECEEDDCDDDDCCC@??CCDDDCC>CCA>@>>><?BDCA#
@9FU
TGGCAGGCGACGGGCAAATGAGAACAGCAACATACAGCTGCCTTATGACTCAAGATGGGAGTTTCCAAGAGATGGACTAGTGCTTGGTCGGGTCTTGGGGT
+
@@@DDDDDF6DDHG>GFGGAD9B?DDBDGGDE>FGCDH>3@DHCGAH?E>=C>@CEEEACC(5>@;;CCBB<@3>?CAA:(4@CCC<:><B9<<CC>><B5
@9FV
GCAAATGAGAACAGCAACATACAGCTGCCTTATGACTCAAGATGGGAGTTTCCAAGAGATGGACTAGTGCTTGGTCGGGTCTTGGGGTCTGGAGCGTTTG
+
DDCEDDDEDCCCCDDDEEEDDDCB@DDDDEEEDEFFFFFFFHGHHIJIGEIJIJIJJJIJIJIIIDJGIIJJIGBJJJJJJJJJJIJHHHHHFFFFF@CC
@9FW
CTTCAACCACCTTCCCAAACGCTCCAGACCCCAAGACCCGACCAAGCACTAGTCCATCTCTTGGAAACTCCCATCTTGAGTCATAAGGCAGCTGTATGTTG
+
@@@=D?D:AC<DF@EEGEG3FHCAC@?DCD3D=FHI>?GEFHAFCH;=CA7AC=EDDEEECDCCCCCCCCABCCCCCCCC>::>C;CC<<BBCC:@:>@@>
@9FX
CGGGCAAATGAGAACAGCAACATACAGCTGCCTTATGACTCAAGATGGGATTTTCCAAGAGATGGACTAGTGCTTGGTCGGGTCTTGGGGTCTGGAG
+
?:5,3>:>3>>:>A;;5-3B@6.(>AD@@;7=).7...D@ACEIEDAA=/))=DD?8?B?0*BDB?<?:0)D:)D6EF:IEE>EA++:A==A4A8?=
@9FY
CCCATCTTGAGTCATAAGGCAGCTGTATGTTGCTGTTCTCATTTGCCCGTCGCCTGCCTTCTACTCGGCTGATAGTTATAGTCTGACCGATAACATCAATT
+
@CCFFFFFGGFCFIIIIJJEFHJIGHHEGJIGIJJHIJJGGHGGIIIHIGDGIJGIIJIGHIJIJIIDE?EDFFFEECDEC@@C3>CCDDDDDDDDDDCCA
@9FZ
GCCACCTTCCCAAACGCTCCAGACCCCAAGACCCGACCAAGCACTAGTCCATCTCTTGGAAACTCCCATCTTGAGTCATAAGGCAGCTGTATGTTGCTGTT
+
@@=BB?DD;<ADCBF@GBFEGECEG;F=FEF>DG@0?(<C=;=F3=7=@G7==ACEHH@??3)7@(;.(;A>5;3(;@,;C@@9?1((+4@>:BDCC####
@9G0
CAAGACCCGACCAAGCACTAGTCCATCTCTTGGAAACTCCCATCTTGAGTCATAAGGCAGCTGTATGTTGCTGTTCTCATTTGCCCGTCG
+
CADB?8=>;@BC@A>>CCCBCCDCCEEECJIHHDA;F9IGHHCF>IJJJIEEGGGIHGHHDIGDEH@GHC@IGIGEBGHDGGFDFDF@@@
@9G1
CAGCCGAGTAGAAGGCAGGCGACGGGCAAATGAGAACAGCAACATACAGCTGCCTTATGACTCAAGATGGGAGTTTCCAAGAGATGGACTAGTGCTTGGTC
+
@@?DDDDDBFHHHEDB:CEFH@DFEIGGGEHGCHIIIIIIIHHHHEEEDC@ACCCCCCCFCCCCCCCCCCBCBBCCDC>CCBBCCCCCCCCC>ACDCCBC@
@9G2
CCGACCAAGCACTAGTCCATCTCTTGGAAACTCCCATCTTGAGTCATAAGGCAGCTGTATGTTGCTGTTCTCATTTGCCCGTCGCCTGCCTTCTAC
+
########@3:?C>49@CC??BCCDA>>;=?A@C@AECCFDCDCHHHEEFHE@@BHGGDIGHGGHFF>B<GFFFBF>GEGGHG@D;;FD?FFF@@@
@9G3
CAACCACCTTCCCAAACGCTCCAGACCCCAAGACCCGACCAAGCACTAGGCCATCTCTTGGAAACTCCCATCTTGAGTCATAAGGCAGCTGTATGTTGCTG
+
@@@:ABDDHFDHFHGHEGBGBBGHAFEHG@D):BFFGH(7'.=5@==@GE=AHHEFFFF>AE;3;@5;=CCCAACCCCCCEC:A@38<?CC:@CDDDACA>
@9G4
GCAAATGAGAACAGCAACATACAGCTGCCTTATGACTCAAGATGGGAGTTTCCAAGAGATGGACTAGTGCTTGGTCGGGTCTTGGGGTCTGGAGCGTTTGG
+
CCCFFFFFHHHHHJIIJJJJJIJIJJJIJJJJJJJJJJJFGEHIJJJJHIBGIIGIIJIIJEHHIIJDGHGIIHHHHFDABCDCDDD=BCDDCBCD<?@D@
@9G5
CTCCAGACCCCAAGACCCGACCAAGCACTAGTCCATCTCTTGGAAACTCCCATCTTGAGTCATAAGGCAGCTGTATGTTGCTGTTCTCATTTGCCCGTCG
+
ACACAB<><:>>95<BBBC@?;3>;;63@DBB3EEEHEFHIGGD@5F@=)=HDIEFIIHGDAGCIGIIIFIIGFDIGIIHEG@EC2ABFADFDA1DD@@?
@9G6
GAAAAACAAAAGAGGATACGAATGGGACTTGAAGTTATACCAGTAACCTCTACTACAAATAAAATTACGGTACAGCAGGGAAGAACTGGAAACTCAGAGAA
+
=<@?+=ADF33+:<A::AC;G=G3B)))1:CEEC1::BF40?DG9B@98)*9*8)))=F:F)8)===)(-7?B;))7@B/,5;2>;@5>>:535::A:>??
@9G7
TGGGACTTGAAGTTATACCAGTAACCTCTACTACAAATAAAATTACGGTACAGCAGGGAAGAACTGGAAACTCAGAGAAAGAAACTGCCCTTCCATCTACA
+
@@@FFFFFGHHHDEG>:EBHEBEHEGHIIIIGIGIIIEHIIGIIIIIIHGDEHEGHHIIIIIIIIIIGGIFHCEHFFFEFCCECCECCCBCCCCCDCCCCC
@9G8
CTCCAGACCCCAAGACCCGACCAAGCACTAGTCCATCTCTTGGAAACTCCCATCTTGAGTCATAAGGCAGCTGTATGTTGCTGTTCTCATTTGCCCGTCGC
+
CCCFFFFFFHHHHJJJJJJJJJJJJICHGIJHIJBIGGIJIIJJJJIIIGDGIGIJIGGGHHFHGHGDDDDECACCCDECDCCDD>>@AA@DDDCDD<BDD
@9G9
TCAGACATGAGAGCTTGTTTTTCACTGGATCTGGCCGAGGGTTTTAGCATCTTCACTGCAACTTTCATGACAGGTTGGGACCGNCGGNNNNNNNNNNNNNN
+
@@@D7D?BFDFDHGGDAFIGIIIII+CBCFGIIIIII):@B(?;BFHHHIHGIIIIIIGHHHHHHFFFFFFEECEECBDDDDD##################
@9GA
CCCGACCAAGCACTAGTCCATCTCTTGGAAACTCCCATCTTGAGTCATAAGGCAGCTGTATGTTGCTGTTCTCATTTGCCCGTNNNNNNGNNNNNNACAAG
+
???DBDD6FFFAFIFGEEFDEHIIHIGIFGGGGFHFHIIIBF@F9B?BGI<DGEHIII@GGIIII>4==A?EHC>;CBB@CD###################
@9GB
TTCCCAAACGCTCCAGACCCCAAGACCCGACCAAGCACTAGTCCATCTCTTGGAAACTCCCATCTTGAGTCATAAGGCAGCTGTATGTTGCTGTTCTCATT
+
CCCFFFFFGHHHHJJJJIJJJJJGHJJJJJJJJJIFJJJJJIGIIJIJIGHIGJHHHHHFFFFFEEEEDCECEDCDC3?@BDCCCCDDDDDDCCA@CACCD
@9GC
AGAAACTGCCCTTCCATCTACAAAAGCTGAGTTTACTTCTCCTCCTTCTTTGTTCAAGACTGGGCTTCCACCGAGCAGGAGATTACCTGGGGCAATTGATG
+
7B@FFFFFHHGGHGIIJIIJIJIIIIIIJJJHIIIIIJJJJJJJJJJJIJGGGHIHGGGGEGGHCGGFGGIJJHHFFEDDDDDDDDDDDDDDDDDCDDDDA
@9GD
CCCGACCAAGCACTAGTCCATCTCTTGGAAACTCCCATCTTGAGTCATAAGGCAGCTGTATGTTGCTGTTCTCATTTGCCCGTCGCCTGCCTTCTACTCGG
+
CCCFFFFFGHHHHJJJJJIJJJJJIJJHJJJJJGIJJJJJJIHIGHIIJJHHIIJJJJHHIIHHIJJIJGFHHHHHHF:@CD>B@DB@BDDDDDDDDDCD7
@9GE
CAGACCCCAAGACCCGACCAAGCACTAGTCCATCTCTTGGAAACTCCCATCTTGAGTCATAAGGCAGCTGTATGTTGCTGTTCTCCCCCCNNNNNNNNNNN
+
@@@FFFFFGGHGHJJGGIGEFGGICEIJGJ@HIIGHGGIIGHIIIGIGGHFFGIJJDDHHIIHC>EBEFF;ACCCECEDCA@CCC@C##############
@9GF
CTCCAGACCCCAAGACCCGACCAAGCACTAGTCCATCTCTTGGAAACTCCCATCTTGAGTCATAAGGCAGCTGTATGTTGCTGTTCTCATTTGCCCGTCGC
+
@@@DDDF:?BFFHJIIIIIIIEEIGGIIIGI?FHGHHIGJI<GHGIJGIC@FGHGIII:=CEEEEEEDD;A>C;C@CDED=:@CC@A3;@CDECCDBBBB<
@9GG
GTTCCTTCAACCACCTTCCCAAACGCTCCAGCCCCCAAGACCCGACCAAGCACTAGTCCATCTCTTGGAAACTCCCATCTTGAGTTTTTTTTTTTTNNNNN
+
??<:;:DD>FC++C:A<<?E>?:AEF1?AF>*:BAA@FF>3?=;AAE;A>C2??B@;3.;.;A3>@AB@35;>A>B9@?>@####################
@9GH
CCGCCTTCCCAAACGCTCCAGACCCCAAGACCCGACCAAGCACTAGTCCATCTCTTGGAAACTCCCATCTTGAGTCATAAGGCAGCTGTATGTTGCTGTTC
+
CCCFFFFFHHHHGJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJGHGHHHHFFFFFFEEDEEDDCDDDCCCCFDDDDDDDDDD@DDDEDDDDDC:
@9GI
CAGTCTCAGACAAGTACTGCCTCCAGAAAAGCCAATTCAAGCGTTGGGAAGTGGCAGGATCGATATGGGAGGGCCGAATCACCTGATCTAAGGAGATTACC
+
CCCFFFFFHHHHHGEHIJHGIIJJJJJJJJIIJJJJJJJIJJJHHIIJEHFCHHJJJJ;;CB5AEDCDFBCC?'==8;18:4<(39@@A(:4?48<?A>:>
@9GJ
CTTCCCAAACGCTCCAGACCCCAAGACCCGACCAAGCACTAGTCCATCTCTTGGAAACTCCCATCTTGAGTCATAAGGCAGCTGTTTTTTTGTNNNNNNNN
+
CCCFFFFFHHHHHJGIIIIJJJJGHIJJIGIHGHIBGIIIIHIII>CHHG@EHEHHFGHDFFFFECCCEC>:@DDDACCDDDA##################
@9GK
CCTTCAACCACCTTCCCAAACGCTCCAGACCCCAAGACCCGACCAAGCACTAGTCCATCTCTTGGAAACTCCCATCTTGAGTCAAANTTTNGNNNNTNNNN
+
@@@:DDDBDDFFDGGGIGGEGHIGDGIJ<FCFAHGA;9BGF6AFGCH?@CAAA=EFFFFFFDECDEAEDDDDDCDDDDCDA>C##################
@9GL
GGGACCGGCTTAATCCATAGGCTGTTCCTTCAACCACCTTCCCAAACGCTCCAGACCCCAAGACCCGACCAAGCACTAGTCCANCCGTGNNNNNNNNNNNN
+
<@<=DD<?DDDHDFGIGGB?FDEGIGCGGGIIGGEGGCGCGEGDHHGGEC@E@=?C?ADFDBB@AAB/==?<<??CCCC:@####################
@9GM
CCCCAAGACCCGACCAAGCACTAGTCCATCTCTTGGAAACTCCCATCTTGAGTCATAAGGCAGCTGTATGTTGCTGTTCTCATTTGCCCGTCGCCTGCCTT
+
@@@DDDFDDHFFHIIIIIIIIIIICFHDGGGIIIIIGIIIIIIIIDIIIIGHFGIIIIDCEHIGHHC@DFFFFFFECECCEEEEDECCCB:@BBBB8?B@>
@9GN
TCTTCCCAAACGCTCCAGACCCCAAGACCCGACCAAGCACTAGTCCATCTCTTGGAAACTCCCATCTTGAGTCATAAGGCAGCTGTATGTTGCTGTTCTCA
+
@@CFFFFDDHFDDGIIIGFHGHJJIDHJJIBDGHDHIIGHGIIHI@DGGCCGGJDCCHHFFFFFCEE>>>CACCDDDCCDD@BCD@CEEDDDDDCCCCDC:
@9GO
GTTCCTTCAACCACCTTCCCAAACGCTCCAGACCCCAAGACCCGACCAAGCACTAGTCCATCTCTTGGAAACTCCCATCTTGAGTCATAAGGCAGCTGTAT
+
@@@DFFFFHHBFFIJIGIEHHGEFHGHIIEICHHHIIBBD>FHIGHIJIICHFFHFDFFFDDEEEDECCCCDDDDDCDDDDACC@CCCD>AC9ABDDDACC
@9GP
GTTCCTTCAACCACCTTCCCAAACGCTCCAGACCCCAAGACCCGACCAAGCACTAGTCCATCTCTTGGAAACTCCCATCTTGAGTCATAAGGCAGCTGTAT
+
@@BFFFFFHHHHHJIIJJJJJJIGIHGGIJJIJIJJJJJIJJJJIJJJIIHEHHHFFFEFFFEECEE@CDDDDDDDDDDDDDDCACDEEDDDA?BDCCCD:
@9GQ
GTTCCTTCAACCACCTTCCCAAACGCTCCAGACCCCAAGACCCGACCAAGCACTAGTCCATCTCTTGGAAACTCCCATCTTGAGTCATAAGGCAGCTGTAT
+
1@@DD?DDFFAD;:<AE@EF?BA3CFD8?D?DDDGFIEC)9)8@@@FF26;AAE:7..;;.;ACD>AC@;;>3>599>?A>A:::@@@>BBB98???B###
@9GR
CTTCCACCGAGCAGGAGATTACCTGGGGGAATTGATGTTATCGGTCAGACTATAACTATCAGACGAGTAGAAGGCAGGCGACGGGGGNNNNNNNGGGAGGN
+
>==A<=AAA)?07;3+?;@+7+:1?>AA)0)(0997?0>>)7.;(;A3)..)7A3=>>@@;3);9<===??>?############################
@9GS
AGCTTACTGTGAAAAACAAAAGAGGATACGAATGGGACTTGAAGTTATACCAGTCTCCTCTACTACAAATAAAATTACGGTACAGCAGGGAAGAACTGGAA
+
<@@FFFDDHFBHHIGIEHCFGIGGECHIIJJCHGGIGEHIIGGGHEEGAFH8BBFHGJDGIIIIJJJJIEHIHGFHHG=>BBDDDECBD@<<8AC9:A?AC
@9GT
GATTACCTGGGGCAATTGATGTTATCGGTCAGACTATAACTATCAGCCGAGTAGAAGGCAGGCGACGGGCAAATGAGAACAGCAACATACAGCTGCCTTAT
+
@@@FFDDEDHBA)CFGEGEH>EHHGGGGAGHGIIIBEHGCHAF>???DB<<5=@FEH<DEAEB<BC?BB@BDDDCCDDCCCC?<ABDDDDCCAC@?<CCC@
@9GU
GCTTAATCCATAGGCTGTTCCTTCAACCACCTTCCCAAACGCTCCAGACCCCAAGACCCGACCAAGCACTAGTCCATCTCTTGGAAACTCCCATCTTGAGT
+
CCCFFFFFHGHHGJIJIJJJJJJJJIBIGIIGIIJJJJIJJJIJJJJJHIHIIGIJJIIJHHFDCEDBDDDDCDDDCDDDEDCC>CCDDCDDDCDCDDCDC
@9GV
CGGCTTAATCCATAGGCTGTTCCTTCAACCACCTTCCCAAACGCTCCAGACCCCAAGACCCGACCAAGCACTAGTCCATCTCTTGGAAACTCCCATCTTGA
+
@@@D?@>BDAFHHIBCHICCGIE<C?CFF;?BFEHHG>99B?FB@?DGHC@FFHG@C;CE=E69>B?;;?AC@:;@AC>ACCCAAA>4>C>@>?A@3:@C4
@9GW
GAGATTACCTGGGGCAATTGATGTTATCGGTCAGACTATAACTATCAGCCGAGTAGAAGGCAGGCGACGGGCAAATGAGAACAGCAACATACAGCTGCCTT
+
CCCFFFFFGFHHHDIJIIJIIJIIIGIIGJJJJJIJJIJGIJJIJJJJJJIGHGGHIJJIIIGHDFDDDDB:;@BDCDDCDDDDB<38ACCCDCDDDDDDA
@9GX
GTTGGGACCGGCTTAATCCATAGGCTGTTCCTTCAACCACCTTCCCAAACGCTCCAGACCCCAAGACCCGACCAAGCACTAGTCCATCTCTTGGAAACTCC
+
CBCFFFFFHHHHHJJIJJJGIIJJHIJGIGJJJIJJJJIJIIIJJJJCGIHHIHHHHHFFFDDDCBCDDDBDDDDDDDDDDDACDDDCDDEDDDCDDCDDD
@9GY
CAGGGAAGAACTGGAAACTCAGAGAAAGAAACTGCCCTTCCATCTACAAAAGCTGAGTTTACTCCTCCTCCTTCTTTGTTCAAGACTGGGCTTCCACCGAG
+
@CCFFFFFDHHGHICHIJJJJJJIJJIFJJJJIJFIIIJJJIJIGJIJIJIGIJGGIHEEHIE7CHIJJJHGGGHHFFFFFFEECC@C?BBC?CACCB?B>
@9GZ
GCAACTTTCATGACAGGTTGGGACCGGCTTAATCCATAGGCTGTTCCTTCAACCACCTTCCCAAACGCTCCAGACCCCAAGACCCGACCAAGCACTAGTCC
+
CCCFFFFFHHHHGJJJJFIJJJIGIIJIIJGGGEG?DGAGFGHAGFHGGGDGFHAHGEHHHHGFFEACABDCCCDBBDDDA?CDDDB@<>BA@AC>AC@@:
@9H0
TCTCAGTCTCAGACAAGTACTGCCTCCAGAAAAGCCAATTCAAGCGTTGGGAAGTGGCAGGATCGATATGGGAGGGGCGAATCACCTGATCTAAGGAGATT
+
CCCFFFFFHHGHHJIIJIIJIIJIJIJJJJJJJIIIJJJJIIJJJJIHIIHIIJIIIJIJJ().:(=;8?CC>ABB#########################
@9H1
TTTAGCATCTTCACTGCAACTTTCATGACAGGTTGGGACCGGCTTAATCCATAGGCTGTTCCTTCAACCACCTTCCCAAACGCTCCAGAACCCAAGACCCG
+
?@;1+?+==:ACFGEAGGIHEH<EDBB>AC+<AH3CG9)?@AEAHBD@BFGC9F;7.6@GEA7=;7=7?BD?@CCC=CC2=B;@B?@@@(38<<@######
@9H2
TTTAGCATCTTGACTGCAACTTTCATGACAGGTTGGGACCGGCTTAATCCATAGGCTGTTCCTTCAACCACCTTCCCAAACGCTCCAGACCCCCAGACCCG
+
@?@BDD4AF8:,,22<?9<<C9@3AF:ACE3AA9;E:):6@:DE0B8CBFFFCADE@CD:=?A>;;BB(55=@@B;=(;=2//<B@>>(8(2(&)2<B??9
@9H3
GTGGGTTTTAGCATCTTCACTGCAACTTTCATGACAGGTTGGGACCGGCTTAATCCATAGGCTGTTCCTTCAACCACCTTCCCAAACGCTCCAGACCCCAA
+
@==DD@DDHHB?DFDEHIIIIGII>CDHGIIIIIIIIGBGHEIC;BGGGGAGHGICED>EH:?@BC@DC@@AAA@BBBBA?CCCCBB?B@BBCCCBBBBB@
@9H4
TTTTTCACTGGATCTGGCCGTGGGTTTTAGCATCTTCACTGCAACTTTCATGACAGGTTGGGACCGGCTTAATCCATAGGCTGTTCCTTCAACCACCTTCC
+
CCCFFFFDHGGDFEHIJJJJCGGGGGGIEHIIIIIGGIJIIHJJGIIJIC=FHGHII=CCHEHEEE?ABDCDDDDDDCACDDDDD:>@CCDD>????<>??
@9H5
CTTGTTTTTCACTGGATCTGGCCGTGGGTTTTAGCATCTTCACTGCAACTTTCATGACAGGTTGGGACCGGCTTAATCCATAGGCTGTTCCTTCAACCACC
+
@@CFADFF?H?A?BFHGHIGDHFHCFHI:FHHIHEG@GGGDHG@FHA@CHEFE>>FFHIIIEGGHGC;?<BBBDDDEDD(5AC@@AA8:((+>C>>@A??#
@9H6
ATCGGTCAGACTATAACTATCAGCCGAGTAGAAGGCAGGCGACGGGCAAATGAGAACAGCAACATACAGCTGCCTTATGACTCAAGATGGGAGTTTCCAAG
+
@@CFFFFFHHHHHIIIIIIJJJJIJIBHEHGIJJFEHIJIGIDHIHBBEDDCEDCEACC?CCBDCCCDDDCCCBCDDDCCDDD@CCCCCCBCB2?CACDCA
@9H7
CTTCCATCTACAAAAGCTGAGTTTACTTCTCCTCCTTCTTTGTTCAAGACTGGGCTTCCACCGAGCAGGAGATTACCTGGGGCAATTGATGTTATCGGTCA
+
@CCDDEFFHHHHHJIIJJJIGHIDHHIGEIIJBIJJJJGIDGGIGIEEHIIIFGFEHIIIGGHH>GEECEC?@DBFEEEACDDB?CCDACCBCDDA?58><
@9H8
CAGGTGAGTCATTATCTTCAGTTCAGACATGAGAGCTTGTTTTTCACTGGATCTGGCCGTGGGTTTTAGCATCTTCACTGCAACTTTCAGGACAGGTTGGG
+
@@@ABDDDCFBDFDGEEGBHIJGIIJGE?BEGC@B)?FE1?DDGHICGEGBGHG@FBHGHGFI8;@?>ACEFDD;@33>;CE>AC@@##############
@9H9
CGTGTGCTTTCATCAGCAGGGTTCAATCCAAAGATATCCAGCTCTTTCTTTGGCTTCTCTGGGTGGTGGCTCAGGAAGCTATCCCTATTCTTATGCAAATA
+
?@;DDBDEDHFDHIGEGGGGHIIHGEE@FHD@GIIEGD@B@FADHIIGJJIG@FGDHIGIGI9858;;16=CHF@);@BC>(6;AC@C@############
@9HA
CGGTCAGACTATAACTATCAGCCGAGTAGAAGGCAGGCGACGGGCAAATGAGAACAGCAACATACAGCTGCCTTATGACTCAAGATGGGAGTTTCCCAGAG
+
==844=222A+A<<<E<AA<,<<8@E:8?E?9)::??D<(7<48::16;7777666>>;(5=?;::AAA:A<>A>A>A:AA####################
@9HB
TGGATCTGGCCGTGGGTTTTAGCATCTTCACTGCAACTTTCATGACAGGTTGGGACCGGCTTAATCCATAGGCTGTTCCTTCAACCCCCGGGNNNNNNNNN
+
@CCFFFFFHGHHHJIJIJJJIJJIJJJIIGJIJIJJJJJIJIJJFJJJD<BFIIIIIJHFFDEEECECCDDDDDDDD@CDDCCCC################
@9HC
CTGGTGCTGATCTTTCTGATTATTTTAATTATGGGTTTAATGAAGATACCTGGAAAGCTTACTGTGAAAAACAAAAGAGGATACGGGGGGGGGGGGNNNTN
+
@@CFBDFFGHFGHJJJJIIIJHHJJI@FGGIGIJJAFHIIJIEHIJIJJJGHIIGIJJIJJJJJGIJGJJIIIIJJJFHHHFFD#################
@9HD
CTGTTCCTTCAACCACCTTCCCAAACGCTCCAGACCCCAAGACCCGACCAAGCACTAGTCCATCTCTTGAAAACTCCCATCTTNNNNNNNNNNNNNNNNNN
+
CCCFFFFFHHHGHIJJIJJJJJGIIIIJIJJIIJJIJJJJJJJIIJJFIIGHHFHHFFEEFFFEEEEEE(>CDDDDDDDDDDD##################
@9HE
CAAATGTGGCCCCAGGTGAGTCATTATCTTCAGTTCAGACATGAGAGCTTGTTTTTCACTGGATCTGGCCGTGGGTTTTAGCNNNANNNNAANNNNNGGGG
+
CCCFFFDFHHHHHGGIFHIIFHIIFGIIIJJJJJJJJJIJJIIGHIJIJIBFHIJJJJJJIIJJJJJJIJJEHFF>ADDDDA###################
@9HF
CCTTCAACCACCTTCCCAAACGCTCCAGACCCCAAGACCCGACCAAGCACTAGTCCATCTCTTGGAAACTCCCATCTTGAGTNNNNNNNNNNNNNNNNNNN
+
@CCFFFEBDHHHGIJIJGGIGIIGIGGIJIJIGIJJIGGIJIIGIHCCHGEHFCEDDEFFFFEEDDCEDDDDDDDDDDDDDD###################
@9HG
CTTCTTCTCAGTCTCAGACAAGTACTGCCTCCAGAAAAGCCAATTCAAGCGTTGGGAAGTGGCAGGATCGATATGGGAGGGGCGAGGAGGGGNNNNGNNNN
+
CCCFFFFFHHGHHJJIJDIIGIHJIHGEIGHIJIGCHIJGIJIGGIJIDHBBFHGHGGGGIGHIIH###################################
@9HH
GCTCCAGACCCCAAGACCCGAGCAAGCACTAGTCCATCTCTTGGAAACTCCCATCTTGAGTCATAAGGCAGCTGTATGTTGCTGTTCTCATTTGCCCGTCG
+
CCCFFFFFHHHGHJJJJJJJJJJIJJJIJJJJJJJJJJJJJJJJJJJJIJIJIJJJJJIJIJJHHHHHHFFFEEEEEDFDDDDDDCDEDEEEEEDDDDDDB
@9HI
GGAGATTACCTGGGGCAATTGATGTTATCGGTCAGACTATAACTATCAGCCGAGTAGAAGGCAGGCGACGGGCAAATGAGAACAGCAACATACAGCTGCCT
+
CCCFFFFFHHHHHIJJJJJJJIJIJJJJJJJHIJJJJJJJJJJIIJIJJJGIHGFGGHIJJAEHHFFCDDDDDDDDCDDDDDCDDDDDDDD@:@>>C@CBC
@9HJ
CCCGACCAAGCACTAGTCCATCTCTTGGAAACTCCCATCTTGAGTCATAAGGCAGCTGTATGTTGCTGTTCTCATTTGCCCGTCGCCTGCCTTCTACTCGG
+
@@@FFFFFHHGHHJGHCGEHGIJJJJIGHGIJJJIGIIJIJJGIHGGIGIF>DHGHEICFGJJJJJJGIHHHHHHHGFFBDBAABDDBD?BDDCCDCDDD<
@9HK
CTTCCACCGAGCAGAAACAGCACTTCTTCTCAGTCTCAGACAAGTACTGCCTCCAGAAAAGCCAATTCAAGCGTTGGGAATTGGCAGGATCGATAAGGGAG
+
??<DB8DBA?<)<:EE<EE3@ECCE<EE*CDED?9B@BAB:B?D09?DB**?B=C@:C;8=(.@CC3??ACDDD@?@########################
@9HL
GGCCTACTCCGGCTGCCAGACCTCGCAGCTCAGCCAACTCTTTGTCTTCGTTTATAAGCACTGTCACCCCTTCCTTGGCACTTTTTTGATTCTTTAATCTT
+
CCCFFFFFHHGHHJJIJJJJJIJJJJJJJJJIIIJGIJJJIJJIGIJJJJJJJJJJHHHHHHFFFFFFEDDDDDDDDDDDDDDDDDBDB@C@CDCCDDDD@
@9HM
CCTGGTGCTAGTTGCAAAGACACAAGTGGGGAAATCAAAGTATTACAAGTCTGGCATAGAAGATTAAAGAATCAAAAAAGTGCCAAGGAAGGGGTGACAGT
+
CCCFFDFFGHHHGJJJJJJIIJJJJJFHIJJJJJJIJJJIHIJIJJJJIHHIGJJJJIHIGIJJIJJJJJJHHHHHHFDDCEDCDDDDDDDDDB8<ACCC4
@9HN
CCTGGTGCTAGTTGCAAAGACACAAGTGGGGAAATCAAAGTATTACAAGTCTGGCATAGAAGATTAAAGAATCAAAAAAGTGCCAAGGAAGGGGTGACAGT
+
@@@DFADDFHHHHIJJIDHEHHIIEIHHGGIIIJIIJJJJFHEGIGHJJIIGIIIJJGGIJJCHIJGDHJJHFHHGHFDBCEDDCCBDDDDDDB'0?CAC3
@9HO
CCTGGTGCTAGTTGCAAAGACACAAGTGGGGAAATCAAAGTATTACAAGTCTGGCATAGAAGATTAAAGAATCAAAAAAGTGCCAAGGAAGGGGGGACAGT
+
CCCFFEEDHHHHGIIIJIJ@FGHCDECFGHJGGIJJJIGIBGIIGGEIIBFIG@HIJIJIIIIIJJJIJGIGHHHHGECD@ACDDDDDBDDDD=&5>BDD4
@9HP
CCCGAGGGAAGGCAGGAAGATTTTCAATCTCCTCTTGGGTTGGAAGAGTATGTATTGCATAGCAGGCATTAGCCAGGCCTACTCCGGCTGCCAGACCTCGC
+
@@@FBDDDHDHBAEG>FGIJJGIJIIIGIIGIIIGIIIGFFEG>FI@D==@GHGCHGGEHDFFEFBBECED36;A=BADDD<CACD:-<3<<CC888>3<<
@9HQ
CTTTGTCTTCGTTTATAAGCACTGTCACCCCTTCCTTGGCACTTTTTTGATTCTTTAATCTTCTATGCCAGACTTGTAATACTTTGATTTTCCCACTTGTG
+
?@@A;=;?AADFFF;,A?C3C@GDC+4CH@:GG9DG@>3??FBGGFFE61B@FFEFAFCCFF@A=D=;7===CDDBDD3?.;6>@################
@9HR
CTTTGTCTTCGTTTATAAGCACTGTCACCCCTTCCTTGGCACTTTTTTGATTCTTTAATCTTCTATGCCAGACTTGTAATACTTTGATTTCCCCACTTGTG
+
@@@FDDFFHHHFHIJIJJJIFGIEHGIIGGIJIJGJJ@HIGHIJJIJJIJDHHEIJIJIIIIIGGEHIHHEEHCF>CFFFDEDEEE>CDEACCCCDBDCC#
@9HS
GCCTACTCCGGCTGCCAGACCTCGCAGCTCAGCCAACTCTTTGTCTTCGTTTATAAGCACTGTCACCCCTTCCTTGGCACTTTTTNGATTCTTTAATCTTC
+
@C@DDDDDFFAFHDHGIDHGGCAHA@?FFEEFHE<D=?DF=CDFFDGGDF@DC@@AHHEHC=?CD@DCCAAC?C;;3>@CAC@C>#,,28<@DCCCCC3AA
@9HT
CAGACCTCGCAGCTCAGCCAACTCTTTGTCTTCGTTTATAAGCACTGTCACCCCTTCCTTGGCACTTTTTTGATTCTTTAATCTTCTATGCCAGACTTGTA
+
@C@FFFFFHHFHGJJJJJJJJIJJJJIIJJIIJJGHIIJJIDFHGJIIHJIIIIIJGIJIEHEIHHHHHFDDDDDDDDDDDDDDDEDDEEDDDDDDDDDCC
@9HU
CAGACCTCGCAGCTCAGCCAACTCTTTGTCTTCGTTTATAAGCACTGTCACCCCTTCCTTGGCACTTTTTTGATTCTTTAATCTTCTATGCCAGACTTGTA
+
+=@?BB:A?:CD6C<3CGIID?EAGGFF?FFIIIBBBFFFF<9B@<???FF>FA7F@C@A7)7=?7?3;@CC@@A(5@>@>;5>AABB:>:@A@@BA>:4>
@9HV
GTTAGAAGGAGGTGGTAACCCTGGTGCTAGTTGCAAAGACACAAGTGGGGAAATCAAAGTATTACAAGTCTGGCATAGAAGATTAAAGAATCAAAAAAGTG
+
;:?DDD4DFHHFCGBHDFHHBGE;?GHGI@HIIICFGIEIAHGIIIIIGIDGCGHIIC;.=@AEEEFF?CHEDEEECCCCCACCCACCCBCCCCCC?BBCC
@9HW
GTTAGAAGGAGGTGGTAACCCTGGTGCTAGTTGCAAAGACACAAGTGGGGAAATCAAAGTATTACAAGTCTGGCATAGAAGATTAAAGAATCAAAAAAGTG
+
8:?DBB?AFFHFFFG@FHGFGI@FAFGHGIE@GIGDFDDHGGH?DDBHGGAACHIIEGHHGI@EDEACAHCDDCCDCCCCCCC@CACCC?CCCA@C?>@>:
@9HX
GCCGGACCTCGCAGCTCAGCCAACTCTTTGTCTTCGTTTATAAGCACTGTCACCCCTTCCTTGGCACTTTTTTGATTCTTTAATCTTCTATGCCAGACTTG
+
CCCFFFFFGHGGHIIJJJJJJIJJJIJJJJHJIJIJGIJJJGIIJJJJJJFHIJJJJHHHHHFFFFFEDEEEDDDDDEDEDDDDDDDEDDEDDDDDDBCCC
@9HY
GTTAGAAGGAGGTGGTAACCCTGGTGCTAGTTGCAAAGACACAAGTGGGGAAATCAAAGTATTACAAGTCTGGCATAGAAGATTAAAGAATCAAAAAAGTG
+
CCCFFFFFGHHHCGHHIJJJJJJJFHJJJJJJJIJJJJJJJJJJIHIJJJJJJIIJJJJDHIIJJHHHHHFFFFFFDEEEEEDDDCDDDDDDDDDDDDBCC
@9HZ
TGATGAGTTAGAAGGAGGTGGTAACCCTGGTGCTAGTTGCAAAGACACAAGTGGGGAAATCAAAGTATTACAAGTCTGGCATAGAAGATTAAAGAATCAAA
+
C@@FFFFFHGHHGIJJGI<FCEHGIIIIII<FGIJIJJJJJJJJJJJJJIHFGIJJJJIJJJJJH?EHGEHFFFFFFFEDEEEDDCDDDDDDDDDDDDDDD
@9I0
CCGCCTACTCCGGCTGCCAGACCTCGCAGCTCAGCCAACTCTTTGTCTTCGTTTATAAGCACTGTCACCCCTTCCTTGGCACTTTTTTGATTCTTTAATCT
+
???BDDD:D<?;<1EEEEE>EEE>1:C?@DDEE*889BCBBCIEIICEIACDCCDA;=7AD@A@AAAAA@>???;AA>>>AA?AAAA?974:B:>AAAAAA
@9I1
CCGCCTACTCCGGCTGCCAGACCTCGCAGCTCAGCCAACTCTTTGTCTTCGTTTATAAGCACTGTCACCCCTTCCTTGGCACTTTTTTGATTCTTTAATCT
+
?@?BB?DDHHHF:FHFDBC9CC?:DCFGGIFGIEBHIDBGCCB@C=A7CHGDHHHHEHHE>>@>.;;@C>>===>CCACCC>?@@@C><BCC>ADCCC@>A
@9I2
CCGCCTACTCCGGCTGCCAGACCTCGCAGCTCAGCCAACTCTTTGTCTTCGTTTATAAGCACTGTCACCCCTTCCTTGGCACTTTTTTGATTCTTTAATCT
+
CCCFFFFFHHHHHJJJJJJJIJJJJJJJJJJJJJJJJJJJJIJJJJJJJJIJJJHHHHHHFFFFFEEEEEDDDDDDDDDDDDDDDDDDDDDDECEDDDDDC
@9I3
TGTACCTTGATGAGTTAGAAGGAGGTGGTAACCCTGGTGCTAGTTGCAAAGACACAAGTGGGGAAATCAAAGTATTACAAGTCTGGCATAGAAGATTAAAG
+
@@@FFFFFHHHFFGAFHIIJJJIEGAFGFGHIJJIIIHHHIGIGIGFGIEGHHHJIGIFGHIHHDHEHHHGFBDEFDDECCCEEDDDCDCCCDDDDDDCC:
@9I4
CCGGCTGCCAGACCTCGCAGCTCAACCAACTCTTTGTCTTCGTTTATAAGCACTGTCACCCCTTCCTTGGCACTTTTTTGATTCTTTAATCTTCTATGCCA
+
1+?A;=:DD?BDDBEE+CAEIC?<?@31B?BDDDCC4?4BDDDDDCD8B@3@A;=77AD>DAC>D@737;;@>@;>>A:;5;>(55::>A>AA>AA>:>>>
@9I5
CAGGCATTAGCCAGGCCTACTCCGGCTGCCAGACCTCGCAGCTCAGCCAACTCTTTGTCTTCGTTTATAAGCACTGTCACCCCTTCCTTGGCACTTTTTTG
+
;@7=;DDBBAHFDI?GHGGIBHEG:G@@CCB?GHGIDDBB<GIGCCGG>E;=EGEECAAEDDB.;=BCDDCCCC>AC5>A:<=?<<C>@>>9@:9>>CCB<
@9I6
GTTTGTACCTTGATGAGTTAGAAGGAGGTGGTAACCCTGGTGCTAGTTGCAAAGACACAAGTGGGGAAATCAAAGTATTACAAGTCTGGCATAGAAGATTA
+
CCCFFFFFHHHHHJJIJJHEIHGJJJJICFGGHIIJIIEGFHIJJJIIJJIIIIGHJJIIIHGIJJHHHHFDDFF7?BCCEEEECDEDCDDDDCDD@CCDD
@9I7
GTTTGTACCTTGATGAGTTAGAAGGAGGTGGTAACCCTGGTGCTAGTTGCAAAGACACAAGTGGGGAAATCAAAGTATTACAAGTCTGGCATAGAAGATTA
+
C@BFFFFFHHHHFGJFFGIIJIIJJIJJ?FHGHGIJJJJIHHJJJJHJJJIJIJJJJJJJJGHIJJJHGGHFFFFCDEEEDDCEDDDCDDDDCACDDDDCD
@9I8
ACCGTTTGTACCTTGATGAGTTAGAAGGAGGTGGTAACCCTGGTGCTAGTTGCAAAGACACAAGTGGGGAAATCAAAGTATTACAAGTCTGGCATAGAAGA
+
@@@@B;BDFHHFDHIBFHBEBFHDHEHCFG@ECHDGEDGHFHGDEGGDAF<DGGCF@8=BGHFCCAHEB?B;;BDE@C>;6;;AC>C-5>A<@AC>5@###
@9I9
ACCGTTTGTACCTTGATGAGTTAGAAGGAGGTGGTAACCCTGGTGCTAGTTGCAAAGACACAAGTGGGGAAATCAAAGTATTACAAGTCTGGCATAGAAGA
+
@BBFDDFFFHHHHJJJJJJJHHIIIJJJJJJCGHHHHIGIJGIGHHIEIHIIHEHIJJJJIJGGDHHIGHFFFFEECE>A@DDDDDDCCDDDCDCDCCDD5
@9IA
ACCGTTTGTACCTTGATGAGTTAGAAGGAGGTGGTAACCCTGGTGCTAGTTGCAAAGACACAAGTGGGGAAATCAAAGTATTACAAGTCTGGCATAGAAGA
+
<??DADBD?FHFHIIFGIBGACBHHFGHGIB1?C:?CGGDGGH@FEGGC3?BG@GGCFFGGF;F7@DGFEE?DE@ACCCCDEECCCC@CDC?C?CCCC>@>
@9IB
TACCGTTTGTACCTTGATGAGTTAGAAGGAGGTGGTAACCCTGGTGCTAGTTGCAAAGACACAAGTGGGGAAATCAAAGTATTACAAGTCTGGCATAGAAG
+
C@@FFFDDHHHFAHIJGGJJJIHGGIIIIEIIC;C?FHIIJGGJFGGJJIJIGHHGGIEGEHEHGHGBGFBEEDEEDEEA@DCFDCDD>CDDCCCCC>CC#
@9IC
GTTACCGTTTGTACCTTGATGAGTTAGAAGGAGGTGGTAACCCTGGTGCTAGTTGCAAAGACACAAGTGGGGAAATCAAAGTATTACAAGTCTGGCATAGA
+
CCCFFFFFHHHHHJJJJJJJJIJJJJJJIJJJJJCGHGIJJJJJJJHIIJHIJJJIJJJJJJJJJJJ=CHHFDDDEDEEDDACDDFDDDDCDEDDDDDDDD
@9ID
GGACATCGTTACCGTTTGTACCTTGATGAGTTAGAAGGAGGTGGTAACCCTGGTGCTAGTTGCAAAGACACAAGTGGGGAAATCAAAGTATTACAAGTCTG
+
C@@FFFFFHFHHHJHGIIIGIIJJIEHIIEGHIJJGJJFGI:DDGFHGIIHHIGGIGDFFGIJIGAGHHDFCEEBDCCBDDDDDDCDD>ADCDDDDC>@>A
@9IE
GGACATCGTTACCGTTTGTACCTTGATGAGTTAGAAGGAGGTGGTAACCCTGGTGCTAGTTGCAAAGACACAAGTGGGGAAATCAAAGTATTACAAGTCTG
+
CCCFFFFFHHHH>GIJJJFIIJJJJIJIFHBFEHIIJJIJJBGIHHHHIJJJICGHIIJIHJJIJIJFHHHGDFDFFDDDDDDDDDDD:ACDFDDDDCDED
@9IF
GTTTATAAGCACTGTCACCCCTTCCTTGGCACTTTTTTGATTCTTTAATCTTCTATGCCAGACTTGTAATACTTTGATTTCCCCACTTGTGTCTTTGCAAC
+
@@@DDDADFCDFFHHDHDGGIICGBHABDFHDCGEGIIBFGEEHGIGGGDHHG@CCGCGIG>FGHDGEGHEAECHE;@EFFC@AECEAACC=CCCAAA>CC
@9IG
TGGACATCGTTACCGTTTGTACCTTGATGAGTTAGAAGGAGGTGGTAACCCTGGTGCTAGTTGCAAAGACACAAGTGGGGAAATCAAAGTATTACAAGTCT
+
CCCFFFFFHHHHHJJJJJJIIJJJJJIJJHIHIHJIJJJIJJBGHFIIJJIJJJJJJJJJJJIJJJJHHHFHFFFEFEDDDDDDDDDDD@CEFEDDDDCD3
@9IH
GTTTATAAGCACTGTCACCCCTTCCTTGGCACTTTTTTGATTCTTTAATCTTCTATGCCAGACTTGTAATACTTTGATTTCCCCACTTGTGTCTTTGCAAC
+
@BCFFFFFHHHHHJIJJJJJJJJJJJJJJJJIHIJJJJJIIJIJJJIJJJHIJJJJJJJJJJJJJJJJJHHHHHGHFFFFFFFCECEDDDDDCDDDDDDC@
@9II
AGATGAGAGTGGACATCGTTACCGTTTGTACCTTGATGAGTTAGAAGGAGGTGGTAACCCTGGTGCTAGTTGCAAAGACACAAGTGGGGAAATCAAAGTAT
+
@@BFFFFFHFHHHIJIJJIJIJJJIJJJJIJJJJJIJJHHDHHIJJJJJJHDGIGHIJJJJJJGHIHHHCEHFFFFFDEDDEDDCCDDDDDDCDDDCD@CD
@9IJ
AACGTAGAGTATGAAGATGAGAGTGGACATCGTTACCGTTTGTACCTTGATGAGTTAGAAGGAGGTGGTAACCCTGGTGCTAGTTGCAAAGACACAAGTGG
+
@@BFDEFFHFHHHJJJIGIJJIJFHGIIIIIJJJIJJJGIIIGHIJIIJIJIIJGGIJJJJIJJJCDHHHHHEDFFFDEEEEEADDDDDDDDDDDDDD@CC
@9IK
GATGAAAACGTAGAGTATGAAGATGAGAGTGGACATCGTTACCGTTTGTACCTTGATGAGTTAGAAGGAGGTGGTAACCCTGGTGCTAGTTGCAAAGACAC
+
=<=<A?AA>8+2<7@2<A,<A<3<+2<7=+2?A@A<AA=A=AA<AAB;(/>7=7=>=AB>/888>A=B;=A(=;,;?>>;>;=;5=?????=9>5=9:=;3
@9IL
GATGAAAACGTAGAGTATGAAGATGAGAGTGGACATCGTTACCGTTTGTACCTTGATGAGTTAGAAGGAGGCGGTAACCCTGGTGCTAGTTGCAAAGACAC
+
=+1<12+<+<A++<7,2<AC@B+AA++<=AC73*:**:1:AAB4AA>ABB<ABBB<>=)==A;7)7=26=A##############################
@9IM
GATGAAAACGTAGAGTATGAAGATGAGAGTGGACATCGTTACCGTTTGTACCTTGATGAGTTAGAAGGAGGTGGTAACCCTGGTGCTAGTTGCAAAGACAC
+
=+?DDDD4D@<AFAFEGFC>E@4CC9<AC2A8?:EEDGIIFEEFFGIIIFEEFFFGIGFF@F=;@;=@EEE?=?9?@>ACCC?>?AB>BBDAAAA<AB@B?
@9IN
GATGAAAACGTAGAGTATGAAGATGAGAGTGGACATCGTTACCGTTTGTACCTTGATGAGTTAGAAGGAGGTGGTAACCCTGGTGCTAGTTGCAAAGACAC
+
CCCFFFFFHHFHHDHADGHGIJCHGGHHICDHGIGIHGIJJJJJJJIJJIJJJJJEHJGHIGEIGGIGGIH5A?<@DECCEED>AC@CDDEDDCDDDDDDC
@9IO
CCAACTCTTTGTCTTCGTTTATAAGCACTGTCACCCCTTCCTTGGCACTTTTTTGATTCTTTAATCTTCTATGCCAGACTTGTAATACTTTGATTTCCCCA
+
CCCFFFFFHHHHHJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJHHHHHHFFFFFEDEEDEEEDDDEDDDDEDCCD<
@9IP
GGATTCTGATGATGAAAACGTAGAGTATGAAGATGAGAGTGGACATCGTTACCGTTTGTACCTTGATGAGTTAGAAGGAGGTGGTAACCCTGGTGCTAGTG
+
@C@FFFFFHGHHHJJJJJJJ@GHHJEHHHIJJEII@FHFCDGGIIIIGGIHIHIGIJJHIIDHIJHIJJJIGHHHHHHEFF1=A>CACCBBC<:<ACCCD#
@9IQ
CTCAGCCAACTCTTTGTCTTCGTTTATAAGCACTGTCACCCCTTCCTTGGCACTTTTTTGATTCTTTAATCTTCTATGCCAGACTTGTAATACTTTGATTT
+
CCCFFEFFGHHHHIIJGGIIIHGHJIIJJGIJIIJJIJJJIJIJJJJIGGGGHIHIJJJGHIJGDHHHGHGHFFFFFFEDEDCDDDCDDDFEDDDDDDCDC
@9IR
CTCAGCCAACTCTTTGTCTTCGTTTATAAGCACTGTCACCCCTTCCTTGGCACTTTTTTGATTCTTTAATCTTCTATGCCAGACTTGTAATACTTTGATTT
+
<@@DDDFFHFFHHJIIFEHIGHGIJGGGIIGEGIGEHHFFIHFGIFGHAFHGHIIJJJIJFHIGIHHHGGGHFFFFCDCCCCE@CDDCD@CCCCDDDACC;
@9IS
CTGAAGTGGATTCTGATGATGAAAACGTAGAGTATGAAGATGAGAGTGGACATCGTTACCGTTTGTACCTTGATGAGTTAGAAGGAGGTGGTAACCCTGGT
+
CCCFFFDFHHHHHJJIJJJJIJJJJJJFGIIJGIIIJJJIJJIJIJFHIJFHIJJIHIJJJIIJJHIJJJJHFHHHHFEFFFFFEEDD=AB?CCDDDDDD5
@9IT
CCACTGTCACCCCTTCCTTGGCACTTTTTTGATTCTTTAATCTTCTATGCCAGACTTGTAATACTTTGATTTCCCCACTTGTGTCTTTGCAACTAGCACCA
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJIJJGIJJJJJIIJJJJJIJHIJJJJJJIJJJJJJJJJJJJHHHHHFFFFEDEEEEEDDDEDDDDDDCDD<
@9IU
TCCCCCTTCCTTGGCACTTTTTTGATTCTTTAATCTTCTATGCCAGACTTGTAATACTTTGATTTCCCCACTTGTGTCTTTGCAACTAGCACCAGGGTTAC
+
CCCFFFFFHHHHHJJJJJJJJJJJIJJJJJJJJJJJJJJJJIIJIJIJJJJJIJJJJJJJJIJJJJJJJJHHHHFFFFFFEDCEDEEDDDCCDDDDDCDDD
@9IV
CTGAAGTGGATTCTGATGATGAAAACGTAGAGTATGAAGATGAGAGTGGACATCGTTACCGTTTGTACCTTGATGAGTTAGAAGGAGGTGGTAACCCTGGT
+
CCCFFFDEHHHHHJJGIJJJIJJJJJJGHIIJFGHJJGIGIJJJJIDFHGGHJJJJIJJJJJJJJGIJJJJHFHFEHFFFFFFFEEDC=AB@CDDDDDDD#
@9IW
CTGAAGTGGATTCTGATGATGAAAACGTAGAGTATGAAGATGAGAGTGGACATCGTTACCGTTTGTACCTTGATGAGTTAGAAGGAGGTGGTAACCCTGGT
+
CCCFFDDDFAFHHIICEGIIJ@IGCHEDGCFHFCEGH@GFHDDFHIHIIJFHEAFHIHGEH;FGICGAGGBHEHHHH;B;BDDFC@?=,;=3>@@ABBCD#
@9IX
TTTATAAGCACTGTCACCCCTTCCTTGGCACTTTTTTGATTCTTTAATCTTCTATGCCAGACTTGTAATACTTTGATTTCCCCACTTGTGTCTTTGCAACT
+
@@@DFFFDHHHFFIIGGGHIJEHIGE@BHIG@DCFAHAGGHIIIIIIJIJFFGGGGEGCHEGCHDGGIHJFHGHHHFBBCBC@CCCCCCD=CCDCDDDDD?
@9IY
CCTGAAGTGGATTCTGATGATGAAAACGTAGAGTATGAAGATGAGAGTGGACATCGTTACCGTTTGTACCTTGATGAGTTAGAAGGAGGTGGTAACCCTGG
+
@@@FFFFDHHFHHJJJGIIGJJJJJIFIGHIIJFFGIIIJGHGHGIIFFHHHIJEHJIIIGGHHIG@EGJIFHHHBHFDDFF?DCCAAB;??;CC3>??C<
@9IZ
ATTTGAAGTAGTTTATGTGGCTCCTGAAGTGGATTCTGATGATGAAAACGTAGAGTATGAAGATGAGAGTGGACATCGTTACCGTTTGTACCTTGATGAGT
+
CCCFFFFFHHHHHJIIJGIJJJJJJIHJJHHIFGHGIHDGHIIJCHIJJJJGHGH?FHDHIIGHGGGEGCDGGIJJHHHHGFEFCCCCBDDACDCCCDED>
@9J0
TTCGTTTATAAGCACTGTCACCCCTTCCTTGGCACTTTTTTGATTCTTTAATCTTCTATGCCAGACTTGTAATACTTTGATTTCCCCACTTGTGTCTTTGC
+
@B@DDDFFHHHHDGIJJFHIJIJJJIIIJGGIJJIJIIIJJIGIIJJIJGGHIIJJJJJIJJGEIIJHHHHGHHFFFFFFFEDECEEDDDDCCCDCCDDD:
@9J1
ATTGAATTTGAAGTAGTTTATGTGGCTCCTGAAGTGGATTCTGATGATGAAAACGTAGAGTATGAAGATGAGAGTGGACATCGTTACCGTTTGTACCTTGA
+
@CCFDDDFHHGDA<CEAFHGIIGIGIGIIGIBBB9CG@BGB@499@DCGEBDDF<F@?BGFGDFGGIGGHEGA@;@@CEEHFED=BE@A==>?=;(;>@A3
@9J2
ATTGAATTTGAAGTAGTTTATGTGGCTCCTGAAGTGGATTCTGATGATGAAAACGTAGAGTATGAAGATGAGAGTGGACATCGTTACCGTTTGTACCTTGA
+
CCCFFFFFHHHHHEEIHIJJIJIJJJIJJFIGHH?FGFHHIIJ<DH>GGIGIHIJG?DBH8=>FGGGC>F@CCG7@EDEFAE?B=?EED?@C?BDEDDCC#
@9J3
GGCAGTCAACGGAGTTAACCTAAGGGACACAAAGCATAAAGAAGCTGTAACTATTCTTTCTCAGCAGAGAGGAGAGATTGAATTTGAAGTAGTTTATGTGG
+
<@@DB?DEHHHHFIBGHIJIGIIJJJHGIIIJGGBHGGJIIIJIJII@DGG>FGIIJJIJJIIIJIJAEHFF;BDCCE<CEDDDCCEDDCCD@@CCACDD@
@9J4
TTTTGGCAGTCAACGGAGTTAACCTAAGGGACACAAAGCATAAAGAAGCTGTAACTATTCTTTCTCAGCAGAGAGGAGAGATTGAATTTGAAGTAGTTTAT
+
@C@FFFFD?CBDFIIDAAGGHHGCBHI@FCHHI?FHEHBGFHAFGDD@D>FHH@HGIEHGEGCEHII@=)67;;?=;?((5>A>@;CCCCACC########
@9J5
TTTTGGCAGTCAACGGAGTTAACCTAAGGGACACAAAGCATAAAGAAGCTGTAACTATTCTTTCTCAGCAGAGAGGAGAGATTGAATTTGAAGTAGTTTAT
+
@@@DFFD?FHFHFGEGHIHHICHHIIIIGCFHGIIIIIIIIIIIIGEHIIGHIIIECFHCDHIIIIIHHCHCD@B?>?(,;@CCCCCDCCDCCCCC@3>C@
@9J6
GCGGAGGGCTTCACGTTGGGGATGCTATTTTGGCAGTCAACGGAGTTAACCTAAGGGACACAAAGCATAAAGAAGCTGTAACTATTCTTTCTCTGCAGAGA
+
;??DDDDDDB+22<CA?ECDA?0?:DD<DBEIIDADBDB<CAA@@5.7=CDCDCDDDD??AA=>A?AAAAAAA?A>A>:>>>>AAADEEAAAA(:A>A###
@9J7
AACTCTTTGTCTTCGTTTATAAGCACTGTCACCCCTTCCTTGGCACTTTTTTGATTCTTTAATCTTCTATGCCAGACTTGTAATACTTTGATTTCCCCACT
+
@C@FFFFFHHHHHIIIJJIJJJJIJJJJJJJJJJJIJJJJJJJHJGIIIJJIJHIJIIJIIJICHIIJGHHHFFFEFFFEEDEECEEDDDCDDDD@CCCBB
@9J8
CTCTGAGATCCATCCGGGGCAACCTGCTGATAGATGCGGAGGGCTGCACGTTGGGGATGCTATTTTGGCAGTCAACGGAGTTAACCTAAGGGACACAAAGC
+
CCCFFFFFHHHHHJIJJJJIJIIJIJIJJJJJJJJJJJJGIJJJHHHEFFEFDDDD@DDDDDECEDDBDDDDDDCCDDBB?ACEDDDCCD?ABDDBDDDD?
@9J9
CTCATCTCTGAGATCCATCCGGGGCAACCTGCTGATAGATGCGGAGGGCTGCACGTTGGGGATGCTATTTTGGCAGTCAACGGAGTTAACCTAAGGGACAC
+
@@@FFFFFGHGHHJEHJJJIJJDIIJDIJJJJIGIJGHHHIJJIGIGGHH@EFFDEEDDDDDDDDDDEDDDCBDDDCDDDDD@BD?CCDDDDDCDCDDDDB
@9JA
TTTGTCTTCGTTTATAAGCACTGTCACCCCTTCCTTGGCACTTTTTTGATTCTTTAATCTTCTATGCCAGACTTGTAATACTTTGATTTCCCCACTTGTGT
+
BBBFFFFFHHHHHJJJJJIJJIIIJJJJJJJIJJIJIIJJIJJJJIJJGJJJJJJJIJJJJJJJJJJIFFHHHFFFFDDFEEEEECEDEDACCDDDDDDC9
@9JB
CGTTTATAAGCACTGTCACCCCTTCCTTGGCACTTTTTTGATTCTTTAATCTTCTATGCCAGACTTGTAATACTTTGATTTCCCCACTTGTGTCTTTGCAA
+
??@DDDEFHHFDDEHIEGCHGIIGDEGEHBHIE<FHDGIIHIIGCAD99/?BFBFHGGEECHEGE@>@>)??CEEEDFFCD>AA#################
@9JC
GAACACTTCTTCAAAGTCTTCACTGCTACTTTGATTTCTCAACTTCCAACTCCTAAGATGTCCACTGCTGTTCCTTCATACACTTCTCCAAAGGCTACACT
+
=1;++<AAB>CCB<AB,<@BACA?BCB97A+?@?AAABB9*??AA<7AB*0?ABBB*009==4A>A>><=>;;=48)7=7>>=B9A;>)>>>@><;>6;=>
@9JD
CTGGACCATAAAACGTTGCCATCCGGGCTTTACGCAAATAAGTAAGAAGGTCTCCTCCCTCCATCAGTTCCAGGATAATGAATTGGGGTTCATTAAGCAGA
+
@7@DD;BDDB?A4CEEFDEBC+<A@)8C8?B@?FGFFBEFCFCBFBFFCCCDAE==)=5A;?@B3;@DEB@>A############################
@9JE
CTGTCACCCCTTCCTTGGCACTTTTTTGATTCTTTAATCTTCTATGCCAGACTTGTAATACCTTGATTTCCCCACTTGTGTCTTTGCAACTAGCACCAAGT
+
?@;=BD?3=<CC8FHEHGA>G>CHC3C:1CG?GHGBF9D>F?D9*999D<(<3)B8)===@)=;==CE47?A?EB6@;@:(.>@;@;@A@###########
@9JF
CACCCCTTCCTTGGCACTTTTTTGATTCTTTAATCTTCTATGCCAGACTTGTAATACTTTGATTTCCCCACTTGAGTCTTTGCAACTAGCACCAGGGTTAC
+
@@@ADFFFGHDBFBHHIJIGEHGGHJJIIGIIGHGEGIGGIJB@DGBDFGEBFGFHGEIGGFHGIIGGG9BCE@)77@CDFEDEEDEDDCDDDBDD?<ABD
@9JG
TGATGATGAAAACGAAGAGTATGAAGATGAGAGTGGACATCGTTACCGTTTGTACCTTGATGAGTTAGAAGGAGATGGTAAACTTGGGGCTAGTTGCAAAC
+
;@7DADDDFHBA;?)<+CEFBHFEHI4A<F?FF1:?9:HD<;)0?D?:BDF6==FDCH@##########################################
@9JH
TCCACTGCTGTTCCTTCATACACTTCTCCAAAGGCTCCACTTCCCAGCAAGAGACGCAGAGTCAGTTTTTCCCGAGGGAAGGCAGGAAGATTTTCAATCTC
+
?;@DDDADFDHFFIIIG@DHGGIGGIHGF@FGFGHGIIIEHIGGIGIIEIHGIIIIIIHAG77DGEEEEFEEBBBACD@98?<A???AA8:3>CDDDE@CC
@9JI
GACATCGTTACCGTTTGTACCTTGATGAGTTAGAAGGAGGTGGTAACCCTGGTGCTAGTTGCAAAGACACAAGTGGGGAAATCAAAGTATTACAAGTACTC
+
@=;DDAADFFFDAGE@DE?F>FHD4EFF@?<EB4<D@C;<?BD:DEFFE@888BFFCGFF>;@A7@7?7=A;()7@=>?@9>;A@A@,,;>>>5AAA>>A:
@9JJ
GCCTACTCCGGCTGCCAGACCTCGCAGCTCAGCCAACTCTTTGTCTTCGTTTATAAGCACTGTCACCCCTTCCTTGGCACTTTTTNGATTCTTTAATCTTC
+
@C@DDDDDFFAFHDHGIDHGGCAHA@?FFEEFHE<D=?DF=CDFFDGGDF@DC@@AHHEHC=?CD@DCCAAC?C;;3>@CAC@C>#,,28<@DCCCCC3AA
@9JK
CAGACCTCGCAGCTCAGCCAACTCTTTGTCTTCGTTTATAAGCACTGTCACCCCTTCCTTGGCACTTTTTTGATTCTTTAATCTTCTATGCCAGACTTGTA
+
@C@FFFFFHHFHGJJJJJJJJIJJJJIIJJIIJJGHIIJJIDFHGJIIHJIIIIIJGIJIEHEIHHHHHFDDDDDDDDDDDDDDDEDDEEDDDDDDDDDCC
@9JL
CAGACCTCGCAGCTCAGCCAACTCTTTGTCTTCGTTTATAAGCACTGTCACCCCTTCCTTGGCACTTTTTTGATTCTTTAATCTTCTATGCCAGACTTGTA
+
+=@?BB:A?:CD6C<3CGIID?EAGGFF?FFIIIBBBFFFF<9B@<???FF>FA7F@C@A7)7=?7?3;@CC@@A(5@>@>;5>AABB:>:@A@@BA>:4>
@9JM
GTTAGAAGGAGGTGGTAACCCTGGTGCTAGTTGCAAAGACACAAGTGGGGAAATCAAAGTATTACAAGTCTGGCATAGAAGATTAAAGAATCAAAAAAGTG
+
;:?DDD4DFHHFCGBHDFHHBGE;?GHGI@HIIICFGIEIAHGIIIIIGIDGCGHIIC;.=@AEEEFF?CHEDEEECCCCCACCCACCCBCCCCCC?BBCC
@9JN
GTTAGAAGGAGGTGGTAACCCTGGTGCTAGTTGCAAAGACACAAGTGGGGAAATCAAAGTATTACAAGTCTGGCATAGAAGATTAAAGAATCAAAAAAGTG
+
8:?DBB?AFFHFFFG@FHGFGI@FAFGHGIE@GIGDFDDHGGH?DDBHGGAACHIIEGHHGI@EDEACAHCDDCCDCCCCCCC@CACCC?CCCA@C?>@>:
@9JO
GCCGGACCTCGCAGCTCAGCCAACTCTTTGTCTTCGTTTATAAGCACTGTCACCCCTTCCTTGGCACTTTTTTGATTCTTTAATCTTCTATGCCAGACTTG
+
CCCFFFFFGHGGHIIJJJJJJIJJJIJJJJHJIJIJGIJJJGIIJJJJJJFHIJJJJHHHHHFFFFFEDEEEDDDDDEDEDDDDDDDEDDEDDDDDDBCCC
@9JP
GTTAGAAGGAGGTGGTAACCCTGGTGCTAGTTGCAAAGACACAAGTGGGGAAATCAAAGTATTACAAGTCTGGCATAGAAGATTAAAGAATCAAAAAAGTG
+
CCCFFFFFGHHHCGHHIJJJJJJJFHJJJJJJJIJJJJJJJJJJIHIJJJJJJIIJJJJDHIIJJHHHHHFFFFFFDEEEEEDDDCDDDDDDDDDDDDBCC
@9JQ
TGATGAGTTAGAAGGAGGTGGTAACCCTGGTGCTAGTTGCAAAGACACAAGTGGGGAAATCAAAGTATTACAAGTCTGGCATAGAAGATTAAAGAATCAAA
+
C@@FFFFFHGHHGIJJGI<FCEHGIIIIII<FGIJIJJJJJJJJJJJJJIHFGIJJJJIJJJJJH?EHGEHFFFFFFFEDEEEDDCDDDDDDDDDDDDDDD
@9JR
CCGCCTACTCCGGCTGCCAGACCTCGCAGCTCAGCCAACTCTTTGTCTTCGTTTATAAGCACTGTCACCCCTTCCTTGGCACTTTTTTGATTCTTTAATCT
+
???BDDD:D<?;<1EEEEE>EEE>1:C?@DDEE*889BCBBCIEIICEIACDCCDA;=7AD@A@AAAAA@>???;AA>>>AA?AAAA?974:B:>AAAAAA
@9JS
TGATGAGTTAGAAGGAGGTGGTAACCCTGGTGCTAGTTGCAAAGACACAAGTGGGGAAATCAAAGTATTACAAGTCTGGCATAGAAGATTAAAGAATCAAA
+
?@+ADDDDHHHHHJJIJJFGIFFAHGIJJJCHHHGIHIIIJJIJEHIIIIJHEHIIIIIJIIGJHAEHHHHFFFBFFFDEEEEDDDDDDDACDDDDDDDCC
@9JT
TTTGTCTTCGTTTATAAGCACTGTCACCCCTTCCTTGGCACTTTTTTGATTCTTTAATCTTCTATGCCAGACTTGTAATACTTTGATTTCCCCACTTGTGT
+
@BCFFFFFHHFFHJIIJHJJIIEHIIJJIIJJJJJJJJJFIGIIJJJIHIGIJJIJJIJJIJJJJHJIGGHHHFFCFFFFEECEEACD>CDDCDDBA@C>9
@9JU
CCGCCTACTCCGGCTGCCAGACCTCGCAGCTCAGCCAACTCTTTGTCTTCGTTTATAAGCACTGTCACCCCTTCCTTGGCACTTTTTTGATTCTTTAATCT
+
?@?BB?DDHHHF:FHFDBC9CC?:DCFGGIFGIEBHIDBGCCB@C=A7CHGDHHHHEHHE>>@>.;;@C>>===>CCACCC>?@@@C><BCC>ADCCC@>A
@9JV
TGATGAGTTAAAAGGAGGTGGTAACCCTGGTGCTAGTTGCAAAGACACAAGTGGGNAAATCAAAGTATTACAAGTCTGGCATAGAAGATTAAAGAATCAAA
+
;?+?B=BDB?,2<AEBEEFDF@A<EFA?CB1??@@D?DD<DDDDD@DCDIIBDCC#(5;;CAA4A7@CCC==AA;?AA@D;@AAAAA>A>AA;>>?>>AAA
@9JW
TGATGAGTTAGAAGGAGGTGGTAACCCTGGTGCTAGTTGCAAAGACACAAGTGGGGAAATCAAAGTATTACAAGTCTGGCATAGAAGATTAAAGAATCAAA
+
BC?DFFFDHFHFDGIGHJEFHGHHIJIIJJHJIIJIJJJJJJJIGIJJJIHGHIJJIJJJJIJIHEFHHHHFFFFFFFEEEEEDDDDDDDCCACCDDCCAC
@9JX
CCGCCTACTCCGGCTGCCAGACCTCGCAGCTCAGCCAACTCTTTGTCTTCGTTTATAAGCACTGTCACCCCTTCCTTGGCACTTTTTTGATTCTTTAATCT
+
CCCFFFFFHHHHHJJJJJJJIJJJJJJJJJJJJJJJJJJJJIJJJJJJJJIJJJHHHHHHFFFFFEEEEEDDDDDDDDDDDDDDDDDDDDDDECEDDDDDC
@9JY
CCGGCTGCCAGACCTCGCAGCTCAACCAACTCTTTGTCTTCGTTTATAAGCACTGTCACCCCTTCCTTGGCACTTTTTTGATTCTTTAATCTTCTATGCCA
+
1+?A;=:DD?BDDBEE+CAEIC?<?@31B?BDDDCC4?4BDDDDDCD8B@3@A;=77AD>DAC>D@737;;@>@;>>A:;5;>(55::>A>AA>AA>:>>>
@9JZ
CAGGCATTAGCCAGGCCTACTCCGGCTGCCAGACCTCGCAGCTCAGCCAACTCTTTGTCTTCGTTTATAAGCACTGTCACCCCTTCCTTGGCACTTTTTTG
+
;@7=;DDBBAHFDI?GHGGIBHEG:G@@CCB?GHGIDDBB<GIGCCGG>E;=EGEECAAEDDB.;=BCDDCCCC>AC5>A:<=?<<C>@>>9@:9>>CCB<
@9K0
GTTTGTACCTTGATGAGTTAGAAGGAGGTGGTAACCCTGGTGCTAGTTGCAAAGACACAAGTGGGGAAATCAAAGTATTACAAGTCTGGCATAGAAGATTA
+
CCCFFFFFHHHHHJJIJJHEIHGJJJJICFGGHIIJIIEGFHIJJJIIJJIIIIGHJJIIIHGIJJHHHHFDDFF7?BCCEEEECDEDCDDDDCDD@CCDD
@9K1
GTTTGTACCTTGATGAGTTAGAAGGAGGTGGTAACCCTGGTGCTAGTTGCAAAGACACAAGTGGGGAAATCAAAGTATTACAAGTCTGGCATAGAAGATTA
+
C@BFFFFFHHHHFGJFFGIIJIIJJIJJ?FHGHGIJJJJIHHJJJJHJJJIJIJJJJJJJJGHIJJJHGGHFFFFCDEEEDDCEDDDCDDDDCACDDDDCD
@9K2
ACCGTTTGTACCTTGATGAGTTAGAAGGAGGTGGTAACCCTGGTGCTAGTTGCAAAGACACAAGTGGGGAAATCAAAGTATTACAAGTCTGGCATAGAAGA
+
@@@@B;BDFHHFDHIBFHBEBFHDHEHCFG@ECHDGEDGHFHGDEGGDAF<DGGCF@8=BGHFCCAHEB?B;;BDE@C>;6;;AC>C-5>A<@AC>5@###
@9K3
ACCGTTTGTACCTTGATGAGTTAGAAGGAGGTGGTAACCCTGGTGCTAGTTGCAAAGACACAAGTGGGGAAATCAAAGTATTACAAGTCTGGCATAGAAGA
+
@BBFDDFFFHHHHJJJJJJJHHIIIJJJJJJCGHHHHIGIJGIGHHIEIHIIHEHIJJJJIJGGDHHIGHFFFFEECE>A@DDDDDDCCDDDCDCDCCDD5
@9K4
ACCGTTTGTACCTTGATGAGTTAGAAGGAGGTGGTAACCCTGGTGCTAGTTGCAAAGACACAAGTGGGGAAATCAAAGTATTACAAGTCTGGCATAGAAGA
+
<??DADBD?FHFHIIFGIBGACBHHFGHGIB1?C:?CGGDGGH@FEGGC3?BG@GGCFFGGF;F7@DGFEE?DE@ACCCCDEECCCC@CDC?C?CCCC>@>
@9K5
TACCGTTTGTACCTTGATGAGTTAGAAGGAGGTGGTAACCCTGGTGCTAGTTGCAAAGACACAAGTGGGGAAATCAAAGTATTACAAGTCTGGCATAGAAG
+
C@@FFFDDHHHFAHIJGGJJJIHGGIIIIEIIC;C?FHIIJGGJFGGJJIJIGHHGGIEGEHEHGHGBGFBEEDEEDEEA@DCFDCDD>CDDCCCCC>CC#
@9K6
GTTACCGTTTGTACCTTGATGAGTTAGAAGGAGGTGGTAACCCTGGTGCTAGTTGCAAAGACACAAGTGGGGAAATCAAAGTATTACAAGTCTGGCATAGA
+
CCCFFFFFHHHHHJJJJJJJJIJJJJJJIJJJJJCGHGIJJJJJJJHIIJHIJJJIJJJJJJJJJJJ=CHHFDDDEDEEDDACDDFDDDDCDEDDDDDDDD
@9K7
GTTCCTTCATACACTTCTCCAAAGGCTCCACTTCCCAGCAAGAGACGCAGAGTCAGTTTTTCCCGAGGGAAGGCAGGAAGATTTTCAATCTCCTCTTGGGT
+
CC@FDFDDFBHBFHIJFHHIIHHHIBB>@<FEIIIGGEGIJIJJIIEHEEFF==FH=CFC1CA=5=E<A8A?=??=8<??A(:@CACDCCCCDDDD:4@A?
@9K8
GTTCCTTCATACACTTCTCCAAAGGCTCCACTTCCCAGCAAGAGACGCAGAGTCAGTTTTTCCCGAGGGAAGGCAGGAAGATTTTCAATCTCCTCTTGGGT
+
CCCFFFFFHHHGHJJIHHIJJJJJJJJJJJIJJJJJIGJEIGGGGIIJJJJGBFHIFHIJIIDIIEHEDAABDDDDDDBD@CCDCCCDACCACDCC@:@BB
@9K9
GTTCCTTCATACACTTCTCCAAAGGCTCCACTTCCCAGCAAGAGACGCAGAGTCAGTTTTTCCCGAGGGAAGGCAGGAAGATTTTCAATCTCCTCTTGGGT
+
11++=DD>B:D:AEA??CEBAG4A;?D;?FC><9??CGIIB3D;FEB:06'.)/.=@@FGE;7=5AA>C?@?;=;53<??5>AB#################
@9KA
TTTCAATCTCCTCTTGGGTTGGAAGAGTATGTATTGCATAGCAGGCATTAGCCAGGCCTACTCCGGCTGCCAGACCTCGCAGCTCNGCCAACTCTTTGTCT
+
?@@BDFFFFHHHHIGIIJGHIJJFIII9?BFECCEIIGDGHGIIJJJEHIFFEHDGBFEHIIIEIAEEEEFDEEDDCA?BDDDD@#+(8+88?CCCCCCDC
@9KB
GGACATCGTTACCGTTTGTACCTTGATGAGTTAGAAGGAGGTGGTAACCCTGGTGCTAGTTGCAAAGACACAAGTGGGGAAATCAAAGTATTACAAGTCTG
+
:?@DFEDDHHHHHIGIIJFGHIIJJEHIJJJIIIGIGJGIJBHEGGGJIGHIIGFGIEGHHHIJJJJFHGHHBD;@CBBBBB@CCA@@:ADDDCCCD@CDC
@9KC
GGACATCGTTACCGTTTGTACCTTGATGAGTTAGAAGGAGGTGGTAACCCTGGTGCTAGTTGCAAAGACACAAGTGGGGAAATCAAAGTATTACAAGTCTG
+
C@@FFFFFHFHHHJHGIIIGIIJJIEHIIEGHIJJGJJFGI:DDGFHGIIHHIGGIGDFFGIJIGAGHHDFCEEBDCCBDDDDDDCDD>ADCDDDDC>@>A
@9KD
GGACATCGTTACCGTTTGTACCTTGATGAGTTAGAAGGAGGTGGTAACCCTGGTGCTAGTTGCAAAGACACAAGTGGGGAAATCAAAGTATTACAAGTCTG
+
CCCFFFFFHHHH>GIJJJFIIJJJJIJIFHBFEHIIJJIJJBGIHHHHIJJJICGHIIJIHJJIJIJFHHHGDFDFFDDDDDDDDDDD:ACDFDDDDCDED
@9KE
GGACATCGTTACCGTTTGTACCTTGATGAGTTAGAAGGAGGTGGTAACCCTGGTGCTAGTTGCAAAGACACCAGTGGGGAAATCAAAGCATTACAAGTCTG
+
;???A;D?2ABBDEIDDE<AC<2AAF?E1?EA?D99:?3?@D?B?9BDBB9.=)8A;;7.7=;CC>).?7)(.(.;@=??>5;::>:3(5:A>A>A#####
@9KF
GTTTATAAGCACTGTCACCCCTTCCTTGGCACTTTTTTGATTCTTTAATCTTCTATGCCAGACTTGTAATACTTTGATTTCCCCACTTGTGTCTTTGCAAC
+
@@@DDDADFCDFFHHDHDGGIICGBHABDFHDCGEGIIBFGEEHGIGGGDHHG@CCGCGIG>FGHDGEGHEAECHE;@EFFC@AECEAACC=CCCAAA>CC
@9KG
TGGACATCGTTACCGTTTGTACCTTGATGAGTTAGAAGGAGGTGGTAACCCTGGTGCTAGTTGCAAAGACACAAGTGGGGAAATCAAAGTATTACAAGTCT
+
CCCFFFFFHHHHHJJJJJJIIJJJJJIJJHIHIHJIJJJIJJBGHFIIJJIJJJJJJJJJJJIJJJJHHHFHFFFEFEDDDDDDDDDDD@CEFEDDDDCD3
@9KH
GTTTATAAGCACTGTCACCCCTTCCTTGGCACTTTTTTGATTCTTTAATCTTCTATGCCAGACTTGTAATACTTTGATTTCCCCACTTGTGTCTTTGCAAC
+
@BCFFFFFHHHHHJIJJJJJJJJJJJJJJJJIHIJJJJJIIJIJJJIJJJHIJJJJJJJJJJJJJJJJJHHHHHGHFFFFFFFCECEDDDDDCDDDDDDC@
@9KI
CTACTCCGGCTGCCAGACCTCGCAGCTCAGCCAACTCTTTGTCTTCGTTTATAAGCACTGTCACCCCTTCCTTGGCACTTTTTTGATTCTTTAATCTTCTA
+
@C@FFFDFHHHHHJJJIJJJJJJJJIIJJJIIJJJJJJJJJGIJIIIFHIIIJJJJJHHHGHFFFFDDDEEDDDDDCDDDDDDDDBDDEDEDDDDDDDDDC
@9KJ
CTAAGATGTCCACTGCTGTTCCTTCATACACTTCTCCAAAGGCTCCACTTCCCAGCAAGAGACGCAGAGTCAGTTTTTCCCGAGGGAAGGCAGGAAGATTT
+
??;DDD?B=C?DFGEEHII@AFFIBEAFCFCADH@EFHGGEHIGAHEGGCD3;B9??B?;=CC@'-@AA)7?E;3?@;C@;><8>?@?1<(2?9@<?@(>C
@9KK
CTACTCCGGCTGCCAGACCTCGCAGCTCAGCCAACTCTTTGTCTTCGTTTATAAGCACTGTCACCCCTTCCTTGGCACTTTTTTGATTCTTTAATCTTCTA
+
CCCFFFFFHGHHHJJJJJIJJJIJJJGJIJIJJJJIJIJJJIIJJJJFIIHIGIIJJHHHHHFFFFDDEEEDDDDDDDDDDDDDDBDCEDDDDDDDCDDDC
@9KL
CTACTCCGGCTGCCAGACCTCGCAGCTCAGCCAACTCTTTGTCTTCGTTTATAAGCACTGTCACCCCTTCCTTGGCACTTTTTTGATTCTTTAATCTTCTA
+
???DDDD;)0)022CAEBEEDCAIDDDD>B>BDDD@DDEII.8BB>A@7@CACEDEE@DDFDDDDD@>@(6>AAAA>A?>AAA?>?A>>>AAAA:>AAD>>
@9KM
CAGGCATTAGCCAGGCCTACTCCGGCTGCCAGACCTCGCAGCTCAGCCAACTCTTTGTCTTCGTTTATAAGCACTGTCACCCCTTCCTTGGCACTTTTTTG
+
CCCFFFFFHHHHHJJIJJJJJJJJIJJJJJIJIJJJJJJJJIJJGIJJJJIJJJHHHHHHFFFDFDDEEEEDDDDDDDDDDDDDDDDDDDDDDDDDDDDD>
@9KN
GGAAGAGTATGTATTGCATAGCAGGCATTAGCCAGGCCTACTCCGGCTGCCAGACCTCGCAGCTCAGCCAACTCTTTGTCTTCGTTTATAAGCACTGTCAC
+
BC@FFFFDHGHHHJJJJIJJJGIJJJJIHIGIJEGHIIJIIJJJIHFGIGGHIIIJJIIJHHFFFFFDEEEDDDDDDDDDDCCBDDDDDEEDDCDDCCCDD
@9KO
GGAAGAGTATGTATTGCATAGCAGGCATTAGCCAGGCCTACTCCGGCTGCCAGACCTCGCAGCTCAGCCAACTCTTTGTCTTCGTTTATAAGCACTGTCAC
+
@@@DBDEDHHHBFHIIGIIGIIJIJJJIJIDGEIFIDHIJHFEHHFEGIIIJHJJJJJIIFGFFFFFDEEECDDDDDDCCCCDD?ABDDDDDDDDDDDDDD
@9KP
AACGTAGAGTATGAAGATGAGAGTGGACATCGTTACCGTTTGTACCTTGATGAGTTAGAAGGAGGTGGTAACCCTGGTGCTAGTTGCAAAGACACAAGTGG
+
@@BFDEFFHFHHHJJJIGIJJIJFHGIIIIIJJJIJJJGIIIGHIJIIJIJIIJGGIJJJJIJJJCDHHHHHEDFFFDEEEEEADDDDDDDDDDDDDD@CC
@9KQ
CAGACCTCGCAGCTCAGCCAACTCTTTGTCTTCGTTTATAAGCACTGTCACCCCTTCCTTGGCACTTTTTTGATTCTTTAATCTTCTATGCCAGACTTGTA
+
CC@FFDDFFHDHHHJJIFIGIIAHEHIBEHFHGIBGGGIJGHIGIJIGHGGGHIIJFIJJIIIGGEEEECDACDDFDECCACC@CECCC>@CCCBDCCDDD
@9KR
CAGACCTCGCAGCTCAGCCAACTCTTTGTCTTCGTTTATAAGCACTGTCACCCCTTCCTTGGCACTTTTTTGATTCTTTAATCTTCTATGCCAGACTTGTA
+
?@BFFFFFHGGHHJGIJJJJJJJIJJJJHJJJIIHIJGHIJEIJIJIGHHIEIIJIJ3@GHIJJHHHHGFDDDDCDDDCDDDDDDEDDEDCCDCDDDDDDD
@9KS
CCAACTCTTTGTCTTCGTTTATAAGCACTGTCACCCCTTCCTTGGCACTTTTTTGATTCTTTAATCTTCTATGCCAGACTTGTAATACTTTGATTTCCCCA
+
CCCFFFFFHHHHHJJJJIJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJHHHHHHFFFFFEDEEDEEEDDDEDDDDEDCCD<
@9KT
GATTCTGATGATGAAAACGTAGAGTATGAAGATGAGAGTGGACATCGTTACCGTTTGTACCTTGATGAGTTAGAAGGAGGTGGTAACCCTGGTGCTAGTTG
+
@@@FFFFDHFHHHJIGHGIHIIIJFEIJIIIIJICFFG?DHGIIIGIJEFDGIHHGJJJJJJJIHIJIIIHIHHHHHFFF;?BA@>ACDDDDCCDDCDDA@
@9KU
GGATTCTGATGATGAAAACGTAGAGTATGAAGATGAGAGTGGACATCGTTACCGTTTGTACCTTGATGAGTTAGAAGGAGGTGGTAACCCTGGTGCTAGTG
+
@C@FFFFFHGHHHJJJJJJJ@GHHJEHHHIJJEII@FHFCDGGIIIIGGIHIHIGIJJHIIDHIJHIJJJIGHHHHHHEFF1=A>CACCBBC<:<ACCCD#
@9KV
TGGATTCTGATGATGAAAACGTAGAGTATGAAGATGAGAGTGGACATCGTTACCGTTTGTACCTTGATGAGTTAGAAGGAGGTGGTAACCCTGGTGCTAGT
+
@@@DABDDFDDDFEHIIIHG6AEFFE<F@FCCDGHFCGF>1?CGHIEIIIGHGDGGEHIGHE@FA@EEA==DEEHCCE9(;<(;13-;;(5(,9@<CC@A:
@9KW
TTTCAATCTCCTCTTGGGTTGGAAGAGTATGTATTGCATAGCAGGCATTAGCCAGGCCTACTCCGGCTGCCAGACCTCGCAGCTCAGCCAACTCTTTGTCT
+
@@@DDDDBHFFAFHG>HI++@<<9F;?1?F>G@DFHBBCFHIIIGBGGCHC>FGHHGGGG9;3DC;:=>EBCC@A;ACBB@,355(>A?BC0(:@CA:4>A
@9KX
CTCAGCCAACTCTTTGTCTTCGTTTATAAGCACTGTCACCCCTTCCTTGGCACTTTTTTGATTCTTTAATCTTCTATGCCAGACTTGTAATACTTTGATTT
+
CCCFFEFFGHHHHIIJGGIIIHGHJIIJJGIJIIJJIJJJIJIJJJJIGGGGHIHIJJJGHIJGDHHHGHGHFFFFFFEDEDCDDDCDDDFEDDDDDDCDC
@9KY
CTCAGCCAACTCTTTGTCTTCGTTTATAAGCACTGTCACCCCTTCCTTGGCACTTTTTTGATTCTTTAATCTTCTATGCCAGACTTGTAATACTTTGATTT
+
<@@DDDFFHFFHHJIIFEHIGHGIJGGGIIGEGIGEHHFFIHFGIFGHAFHGHIIJJJIJFHIGIHHHGGGHFFFFCDCCCCE@CDDCD@CCCCDDDACC;
@9KZ
CAGGCATTAGCCAGGCCTACTCCGGCTGCCAGACCTCGCAGCTCAGCCAACTCTTTGTCTTCGTTTATAAGCACTGTCACCCCTTCCTTGGCACTTTTTTT
+
CCCFFFFFHGHHHIIFHIJJJJIJIJJJIJJIJJJJJJIHGIGJJJIHIJIJJJHHHHHHFFFDFDDEEEEDDDDDDDDDDDDBBCDCC@CCDDDDDDCD>
@9L0
CAGGCATTAGCCAGGCCTACTCCGGCTGCCAGACCTCGCAGCTCAGCCAACTCTTTGTCTTCGTTTATAAGCACTGTCACCCCTTCCTTGGCACTTTTTTT
+
1?@DDDFFHHHGHBHHGIIIGGGJGEIBGIIIGEHIJJIJIDGHIICGAGE>EDHHHFBHFFFCEDBEECCDDDAA;>CDDDDBDDDC@@>ACA<A>A:>9
@9L1
TTTATAAGCACTGTCACCCCTTCCTTGGCACTTTTTTGATTCTTTAATCTTCTATGCCAGACTTGTAATACTTTGATTTCCCCACTTGTGTCTTTGCAACT
+
@@@DFFFDHHHFFIIGGGHIJEHIGE@BHIG@DCFAHAGGHIIIIIIJIJFFGGGGEGCHEGCHDGGIHJFHGHHHFBBCBC@CCCCCCD=CCDCDDDDD?
@9L2
ATTTGAAGTAGTTTATGTGGCTCCTGAAGTGGATTCTGATGATGAAAACGTAGAGTATGAAGATGAGAGTGGACATCGTTACCGTTTGTACCTTGATGAGT
+
@@@FFFFFFFDHHIBHB?IEGHIGIIIIHCHHIIIIIIEGGHH>@GIHHGH?BFD8BBD@FC>DC<@@D7@GGIIHEECCHBCFDDEBBEDDDCC3@CCAC
@9L3
ATTTGAAGTAGTTTATGTGGCTCCTGAAGTGGATTCTGATGATGAAAACGTAGAGTATGAAGATGAGAGTGGACATCGTTACCGTTTGTACCTTGATGAGT
+
@@CFFFDF?FHHGIGGHBDGDGIIGIFHGDHGIGH<B@<FGFDBDHIIIGIE;DG?BG4BAFFGC<B=F)=@A@DGEC?CHEB8AAEDACCCDDCC@C###
@9L4
CAGACCTCGCAGCTCAGCCAACTCTTTGTCTTCGTTTATAAGCACTGTCACCCCTTCCTTGGCACTTTTTTGATTCTTTAATCTTCTATGCCAGACTTGTA
+
@<@DDDFFD:C?F>>GEGIADGGEIIICDFE@CFF>GGGCH9FBFE>/BGHG@ACHECEHEIIBHGFEEDAC?CA@CA@>>CA>>CCCDDA>CCBBCCCAC
@9L5
TTCGTTTATAAGCACTGTCACCCCTTCCTTGGCACTTTTTTGATTCTTTAATCTTCTATGCCAGACTTGTAATACTTTGATTTCCCCACTTGTGTCTTTGC
+
@B@DDDFFHHHHDGIJJFHIJIJJJIIIJGGIJJIJIIIJJIGIIJJIJGGHIIJJJJJIJJGEIIJHHHHGHHFFFFFFFEDECEEDDDDCCCDCCDDD:
@9L6
TTGAATTTGAAGTAGTTTATGTGGCTCCTGAAGTGGATTCTGATGATGAAAACGTAGAGTATGAAGATGAGAGTGGACATCGTTACCGTTTGTACCTTGAT
+
=??DDEEF>DHHABEEFGIIGHIIIIIIGIEGEAF@EBGGCGIIEDHGCDHIAGGIIFGHGHIHDFG=FEHFC7CGGA?>EHHFBD<AABA=;>ACC>A@#
@9L7
ATTGAATTTGAAGTAGTTTATGTGGCTCCTGAAGTGGATTCTGATGATGAAAACGTAGAGTATGAAGATGAGAGTGGACATCGTTACCGTTTGTACCTTGA
+
@CCFDDDFHHGDA<CEAFHGIIGIGIGIIGIBBB9CG@BGB@499@DCGEBDDF<F@?BGFGDFGGIGGHEGA@;@@CEEHFED=BE@A==>?=;(;>@A3
@9L8
ATTGAATTTGAAGTAGTTTATGTGGCTCCTGAAGTGGATTCTGATGATGAAAACGTAGAGTATGAAGATGAGAGTGGACATCGTTACCGTTTGTACCTTGA
+
CCCFFFFFHHHHHEEIHIJJIJIJJJIJJFIGHH?FGFHHIIJ<DH>GGIGIHIJG?DBH8=>FGGGC>F@CCG7@EDEFAE?B=?EED?@C?BDEDDCC#
@9L9
CAGGCCTACTCCGGCTGCCAGACCTCGCAGCTCAGCCAACTCTTTGACTTCGTTTATAAGCACTGTCACCCCTTCCTTGGCACTTTTTTGAATCTTTAATC
+
:?1++2=BD?3AD1<)188<3C)1?*?)@D09909B)??;BB))88)/.8=A=A=?DCDDAA@AA@;;>6;9;?=>(:3::::(5>AA#############
@9LA
GAGAGATTGAATTTGAAGTAGTTTATGTGGCTCCTGAAGTGGATTCTGATGATGAAAACGTAGAGTATGAAGATGAGAGTGGAGATCGTTACCGTTTGTAC
+
++1+<?4<C>><BB,7>2<A?CB???C7@BABBA>A9=?:?B3*?*77*:47?BBBBAB0/=8A#####################################
@9LB
GAGAGATTGAATTTGAAGTAGTTTATGTGGCTCCTGAAGTGGATTCTGATGATGAAAACGTAGAGTATGAAGATGAGAGTGGACATCGTTACCGTTTGTAC
+
B@BDFFFFHHHHHJJIJJIIJHJJJJJIJJIIJJJIGHG?FGFHIIGHGIHIIIIIIJJJ;FHCGCEIIIGGDAEHCHI)7?CDFFDFDCDDCBDDDBBDD
@9LC
CTGCCAGACCTCGCAGCTCAGCCAACTCTTTGTCTTCGTTTATAAGCACTGTCACCCCTTCCTTGGCACTTTTTTGATTCTTTAATCTTCTATGCCAGACT
+
@CCFFFFFHHHHHIJJJIJIJIJJJJJJJJJJIJJJJJIJJGGJJIIJIFGDHHIJJHJJJIJHGGEHEDFFFFBD?CDCCEDDCDCDCCDCDDCCCCABD
@9LD
CTTTCTCAGCAGAGAGGAGAGATTGAATTTGAAGTAGTTTATGTGGCTCCTAAAGTGGATTCTGATGATGAAAACGTAGAGTATGAAGATGAGAGTGGACA
+
CCCFFFFAHHGHDHHGICGEGEGHIGIIIJIIGHFGIIIGIJJIJJIJGGGFHII<BF>FHDGGEHEFGEGDHHGHAEHBD;@B>AAE>;;;CAC;5;@CD
@9LE
CTTTCTCAGCAGAGAGGAGAGATTGAATTTGAAGTAGTTTATGTGGCTCCTGAAGTGGATTCTGATGATGAAAACGTAGAGTATGAAGATGAGAGTGGACA
+
CCCFFFFFHHHHHIIIIGHAAFGIIJJJJJJJJJDHIIJJIJIJFIIJJIGBFGIDCHJJGGIJHIIGIGIGDHIG=CEBE7;B@CDC>CC:>@C5;?:A>
@9LF
CTGCCAGACCTCGCAGCTCAGCCAACTCTTTGTCTTCGTTTATAAGCACTGTCACCCCTTCCTTGGCACTTTTTTGATTCTTTAATCTTCTATGCCAGACT
+
CCCFFFFDHHHHHJJJJJJJEHJJJJJIJJJIFHHIIIGGHGIIIIJIJJJJJJJJJJJJJIJGHFHHFFFFFFDDDDDEDEDDDDCDDDDDEEDDDDDDD
@9LG
CAGACCTCGCAGCTCAGCCAACTCTTTGTCTTCGTTTATAAGCACTGTCACCCCTTCCTTGGCACTTTTTTGATTCTTTAATCTTCTATGCCAGACTTGTA
+
==?DDDFDFHGHHIGEGIIGCGGIIGEGHAFHGG@FGGIIG@GCGGE/?B=CFGHGGCEIGEEAAAAEHDD@CDDDCDCCDDDDCEDDE:@CCCBDCCDCA
@9LH
CTATTCTTTCTCAGCAGAGAGGAGAGATTGAATTTGAAGTAGTTTATGTGGCTCCTGAAGTGGATTCTGATGATGAAAACGTAGAGTATGAAGATGAGAGG
+
CCCFFFFFHHHHHIJJJJJGIJIJIJIIIGJJJJJIJJJHHIHGIIJJIJIHIJIBCFFFBGIGHIGCHGIIJIIGGFFFHDEFDA;((>A@;3(5;A###
@9LI
AACTATTCTTTCTCAGCAGAGAGGAGAGATTGAATTTGAAGTAGTTTATGTGGCTCCTGAAGTGGATTCTGATGATGAAAACGTAGAGTATGAAGATGAGA
+
@BCFFFFFHHHHHJJJJIJIIIHICHGHGIJIJJIJJIGII?FHIJJIIJIJJJJJJJJCEHBHICGIIJJIIIEGIHHHHHF@BECEECEEDEDDDC>@3
@9LJ
ATGCATAGCAGGCATTAGCCAGGCCTACTCCGGCTGCCAGACCTCGCAGCTCAGCCAACTCTTTGTCTTCGTTTATAAGCACTGTCACCCCTTCCTTGGCA
+
@@@DDBDDDHHHHEGHHGGCCB;+22<EGI*?DFFDCBFDGHFGDAABFB@>D3?C>ABB:?DECA>@AAB5;?@CCDC::?CA:>A@@@>8<CCCCCCA3
@9LK
GCAGCTCAGCCAACTCTTTGTCTTCGTTTATAAGCACTGTCACCCCTTCCTTGGCACTTTTTTGATTCTTTAATCTTCTATGCCAGACTTGTAATACTTTG
+
BBCFFFFFHHHHGJJJJJJJJJJJJJIJJJJJIJIIJJJJJJJJJJ6F)B*?9F;88.=FHIJ/-7?==AD3@############################
@9LL
TCGGCTGCCAGACCTCGCAGCTCAGCCAACTCTTTGTCTTCGTTTATAAGCACTGTCACCCCTTCCTTGGCACTTTTTTGATTCTTTAATCTTCTATGCCA
+
@@@FFFFFHHHDHIIJIJJIIIJJHIJIIJJJIIJJHGHIGEBFHIIIJJJIIJJJJJJJJHHHHFFFFFEEEEEEDDDDDDDFDECDCCDDDEDDD@CDA
@9LM
CAGGAATTCAATCTTCTCCTGGTCTGTGGAACCCTTCTTCAAAGTCTTCACTGCTACTTTGATTTCTCCACTTCCAACTCCTAAGATGTCCACTGCTGTTC
+
BCCFFFFFHHHHHJJJJJJJIJFHEIJJJIJIGGJJJJJJJIGIDHIIGGIJIJIJJJJJJEGGAHGEGIIIAGIICGGHHEHFCEFEBDBEDDC@@CC>C
@9LN
CGGAGTTAACCTAAGGGACACAAAGCATAAAGAAGCTGTAACTATTCTTTCTCAGGAGAGAGGAGAGATTGAATTTGAAGTAGTTTATGTGGCTCCTGAAG
+
=:=ADDDFHF>FBFFCHGIGGGHIHDGGIICE@DFGII>GGGGGGGIIIIIIII4/0<=CAHGC;=@?EE@EE>BC@BBBCCE@:;;;>@DDD<:@ACC>>
@9LO
TTTTGGCAGTCAACGGAGTTAACCTAAGGGACACAAAGCATAAAGAAGCTGTAACTATTCTTTCTCAGCAGAGAGGAGAGATTGAATTTGAAGTAGTTTAT
+
@C@FFFFD?CBDFIIDAAGGHHGCBHI@FCHHI?FHEHBGFHAFGDD@D>FHH@HGIEHGEGCEHII@=)67;;?=;?((5>A>@;CCCCACC########
@9LP
TTTTGGCAGTCAACGGAGTTAACCTAAGGGACACAAAGCATAAAGAAGCTGTAACTATTCTTTCTCAGCAGAGAGGAGAGATTGAATTTGAAGTAGTTTAT
+
@@@DFFD?FHFHFGEGHIHHICHHIIIIGCFHGIIIIIIIIIIIIGEHIIGHIIIECFHCDHIIIIIHHCHCD@B?>?(,;@CCCCCDCCDCCCCC@3>C@
@9LQ
GCCTACTCCGGCTGCCAGACCTCGCAGCTCAGCCAACTCTTTGTCTTCGTTTATAAGCACTGTCACCCCTTCCTTGGCACTTTTTTGATTCTTTAATCTTC
+
?@@?BDDB:<@?D@CAA?8CE?EEFFBGBDF;9?B???88<B<88B@@2.8;6@@;=)7?;=).).;ACAB;5;>3>;::?@>>ABB7:A:@C@((>C>:>
@9LR
CTCGCAGCTCAGCCAACTCTTTGTCTTCGTTTATAAGCACTGTCACCCCTTCCTTGGCACTTTTTTGATTCTTTAATCTTCTATGCCAGACTTGTAATACT
+
<@@ADDDADHFDDGBEGGIIIJGECGHGCHIIJJIGCEGGIGGIIHIGIGJJIIEGIG>FHIJJIEFFFFFEDEECEEC>CAADEDACDBDDDDCCDDBCC
@9LS
AACTCTTTGTCTTCGTTTATAAGCACTGTCACCCCTTCCTTGGCACTTTTTTGATTCTTTAATCTTCTATGCCAGACTTGTAATACTTTGATTTCCCCACT
+
@C@FFFFFHHHHHIIIJJIJJJJIJJJJJJJJJJJIJJJJJJJHJGIIIJJIJHIJIIJIIJICHIIJGHHHFFFEFFFEEDEECEEDDDCDDDD@CCCBB
@9LT
CTCTGAGATCCATCCGGGGCAACCTGCTGATAGATGCGGAGGGCTGCACGTTGGGGATGCTATTTTGGCAGTCAACGGAGTTAACCTAAGGGACACAAAGC
+
CCCFFFFFHHHHHJIJJJJIJIIJIJIJJJJJJJJJJJJGIJJJHHHEFFEFDDDD@DDDDDECEDDBDDDDDDCCDDBB?ACEDDDCCD?ABDDBDDDD?
@9LU
AAAGAACATGGTGTTCCAATCCTCATCTCTGAGATCCATCCGGGGCAACCTGCTGATAGATGCGGAGGGCTGCACGTTGGGGATGCTATTTTGGCAGTCAA
+
@@@FFDDDHHHHHJJGIIGIGEGHIGHJIJJIJIJJFIGIGGFBEIIIJFIIJJJJJJGHHHFFFDD@BBB@@DCDBBDDBD?@@DCCDCACCBCCBCCD>
@9LV
GGATGATTAAATTTGCTCATCAGATGTGCCTCCTTCAGGAATTCAATCTTCTCCTGGTCTGTGGAACCCTTCTTCAAAGTCTTCACTGCTACTTTGATTTC
+
CCCFFFFFHFHHHEGIIJIIHFIGGCFGHGIIJJJJJJJIIIJIJGIIIIJEEHJIIDHIIGBHI@GGGEGGIGIIICG?EFFEHBCCFB;B@;>CCCA35
@9LW
TTTGTCTTCGTTTATAAGCACTGTCACCCCTTCCTTGGCACTTTTTTGATTCTTTAATCTTCTATGCCAGACTTGTAATACTTTGATTTCCCCACTTGTGT
+
BBBFFFFFHHHHHJJJJJIJJIIIJJJJJJJIJJIJIIJJIJJJJIJJGJJJJJJJIJJJJJJJJJJIFFHHHFFFFDDFEEEEECEDEDACCDDDDDDC9
@9LX
CGTTTATAAGCACTGTCACCCCTTCCTTGGCACTTTTTTGATTCTTTAATCTTCTATGCCAGACTTGTAATACTTTGATTTCCCCACTTGTGTCTTTGCAA
+
??@DDDEFHHFDDEHIEGCHGIIGDEGEHBHIE<FHDGIIHIIGCAD99/?BFBFHGGEECHEGE@>@>)??CEEEDFFCD>AA#################
@9LY
TGAATTTGAAGTAGTTTATGTGGCTCCTGAAGTAGATTCTGATGATGAAAACGTAGAGAATGAAGATGAGAGTGGACATCGTTACAGTTTGTACCTTGATG
+
@@<BD?DD?F??DG<ABFHFFC<3CG;C3?EB<+91*1C?EGABGG*?FBEDF?B@HH*9?FHG<FB<==@@)/5=;=CHE?(?B################
@9LZ
TCCACTTCCAACTCCTAAGATGTCCACTGCTGTTCCTTTATACACTTCTCCAAAGGCTCCACTTCCCAGCAAGCGACACAGAGTCAGTTTTTCCCGAGGGA
+
++:<2<47ABAB8?A<?<33<<<,<?BBA>B9?=AAB**:?9=<AB47*?B>AAAA2/(7==79=>AAA2=7A############################
@9M0
CTGGACCATAAAACGTTGCCATCCGGGCTTTACGCAAATAAGTAAGAAGGTCTCCTCCCTCCATCAGTTCCAGGATAATGAATTGGGGTTCATTAAGCAGA
+
@7@DD;BDDB?A4CEEFDEBC+<A@)8C8?B@?FGFFBEFCFCBFBFFCCCDAE==)=5A;?@B3;@DEB@>A############################
@9M1
GCGGGTAGTGACTGGATAGGGTATAAAATTGCTAGGTGGAAAAAAAGGTTGGGAGTAGGGTAAAACGAGGGAGGCAGTCACTTGGGAAGCCAGGGTGGGG
+
IIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIII
@9M2
CGGGTAGTGACTGGATAGGGTATAAAATTGCTAGGTGGAAAAAAAGGTTGGGAGTAGGGTAAAACGAGGGAGGCAGTCACTTGGGAAGCCAGGGTGGGGG
+
IIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIII
@9M3
GGGTAGTGACTGGATAGGGTATAAAATTGCTAGGTGGAAAAAAAGGTTGGGAGTAGGGTAAAACGAGGGAGGCAGTCACTTGGGAAGCCAGGGTGGGGGC
+
IIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIII
@9M4
GGAAAAAAAGGTTGGGAGTAGGGTAAAACGAGGGAGGCAGTCACTTGGGAAGCCAGGGTGGGGGCGTACAACTCGAGGTCAAAACAGTGCCCAGCTGAGC
+
IIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIII
@9M5
AAAAAAAGGTTGGGAGTAGGGTAAAACGAGGGAGGCAGTCACTTGGGAAGCCAGGGTGGGGGCGTACAACTCGAGGTCAAAACAGTGCCCAGCTGAGCTA
+
IIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIII
@9M6
GGAAAAAAAGGTTGGGAGTAGGGTAAAACGAGGGAGGCAGTCACTTGGGAAGCCAGGGTGGGGGCGTACAACTCGAGGTCAAAACAGTGCCCAGCTGAGC
+
IIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIII
@9M7
CCGACGGGGAATTCTCACAGGAGACGAGGGGGAAAAGGGTTGGGGCGGATGCACTCCCTGAGGAGACGGTGACCGTGGTCCCTTTGCCCCAGACGTCCATG
+
@@@DFFFDDHHHHIJG@HIJJJJIHHIBGHJJGHHGEFD@ACDDDBDDDD@BDDCD?AA@??BDDBBDD@DDCCB5ABBCCB@ACDCDCBBDDDBB9<?>4
@9M8
GGAAGATTGGATTAACCCTCACAGCTTCTATTCCCCGGGCCCCTGATACTACTACTACTACATGGACGTCTGGGGCAAAGGGACCACGGTCACCGTCTCCT
+
CCCFFFFFGGHGHJJIJJIJJJIJIJJJJJJJIHJJJJJJJJJIJIJJJJIIIJJJIIHHHHHHFFFFDDEDDDDB?BBDDDDDDDDBD?@@CCBADBCC>
@9M9
CAGACGTCCATGTAGTAGTAGTAGTATCAGGGGCCCGGGGAATAGAAGCTGTGAGGGTTAATCCAATCTTCCTGCTGTCAAGCAAAAGAACACCTAAAATT
+
@@@DD?DDHFDHHDG<CGHEDH@EHCACAA<?@EFB<?6@0;63.8=;;).@;A7=;,(6666;;CC;>C;>>>C>5>>:55><CACA??C9?8AA:C@A>
@9MA
CACAAATGCAGGATCTTTCTCCAGTACGTGACGGAAGAATTTTAGGTGTTCTTTTGCTTGACAGCAGGAAGATTGGATTAACGCTCACAGCTTCTATTCCC
+
CCCFFFFFHHHGHIJJJJJJJJIIEHHIHIJJJJIGIGIGIJIJJJ?DGGHHIIJJJIJJJIIIJJIJHHHHFDFFFDCCCC(3=@BDDDDDDDCDDEEED
@9MB
TTTCAGAGCACAAATGCAGGATCTTTCTCCAGTACGTGACGGAAGAATTTTAGGTGTTCTTTTGCTTGACAGCAGGAAGATTGGATTAACCCTCACAGCTT
+
CCCFFEFFHHHHHJJIJJJJHGIIIJJJJJJJJIJJGHIJJJIJJJIJJJIIJJCGHGIJJJJIIJJJHHHHHFFFFEBCCEEDDDDCCCCBDDDDDDDD:
@9MC
CTTTCTCCAGTACGTGACGGAAGAATTTTAGGTGTTCTTTTGCTTGACAGCAGGAAGATTGGATTAACCCTCACAGCTTCTATTCCCCGGGCCCCTGATAC
+
?@8BDDDDDFACAC:CGBGIGGAGEFF?EGBGCCFFHIGIGFH<B>9DD3??CGDGGIC;=D)7=)@7;AHDDDCCBA6>>;>A;>>C#############
@9MD
CCGGGCTCTAGTGGCCAATGGTCCATGAGCTTGATTTTCAGAACTTAACTGAAAGTAACTGAAGCTCACAGCTTCTATTCCCCGGGCCCCTGATACTACTA
+
@@<BD<DBFHFBDEBBGGBF>C@EGDHGIDHHIG@AHG>D4:BGHFBDFGBHCGIDCF@C8CFCGGGHIEGGHHHEEHFC>>@AA6>;?=B@C::>+:@C3
@9ME
CTTTGGGTGTCTGCACCCTGATATGATGGGGAACACATCCGGAGCCTTGGTGGGTGCTGAGGAGACGGTGACCGTGGTCCCTTTGCCCCAGACGTCCATGT
+
CCCFFFFDHHHHHJJJJJJJJJIJJIJJJJJIJIJJJJJJJIJIJJJJJJJHHJAEHFFFFFCDACDD>ABDDDBDDDDCDDDDDDDDDDDDDB@BDDEDA
@9MF
GCAAAATTTGCAGAAAGTACAGAAAGTTCTTATATATCCTCTCCCCAGCTCACAGCTTCTATTCCCCGGGCCCCTGATACTACTACTACTACATGGACGTC
+
C@BFFDFFHHGHHBHGIGJJGEHGGJHIGHJJJJJJJJGIIJDFGFAGHGHGIJJJJJHIJGIGI)=FHH8<><AB@@C@>>;;;A>@CA:ACC@CCCB50
@9MG
CTTTCTCCAGTACGTGACGGAAGAATTTTAGGTGTTCTTTTGCTTGACAGCAGGAAGATTGGATTAACCCTCACAGCTTCTATTCCCCGGGCCCCTGATAC
+
@@@=DDFFHHFDHJ;EEHHIIDEAE9GGGIJJCB?FHGAEHGIIIEEGGIIJD@BDFHGCCHAGGIJFHE@BBDFCBCCE@>:@CCA?BBD&09@??3>C@
@9MH
CCCTGCATGACGTCCTTGGAAGGCAGCAGCACCTGTGAGGTGGCTGCGTACTTGCCCCCTCTCAGGACTGATGGGAAGCCCCGGGTGCTGCTGATGTCAGA
+
CCCFFFFDHHHGHGGI@HHJJJIFIIIJIH;GHICBGIIJ9BGHEHEH@FBGGGHIJEEHFFFFCEEDCDCDACDCCB?AABBDB9>@DCACDDDD@CDA3
@9MI
CCTCTCAGGACTGATGGGAAGCCCCGGGTGCTGCTGATGTCAGAGTTGTTCTTGTATTTCCAGGAGAAAGTGATGGAGTCGGGAAGGAAGTCCTGTGCGAG
+
:?@DDDDDADAD;<EHIIGI1;FGHGBH?6BDHHIGGE<?BDGGG<FF@CDFH@HGECGGHHE<E7;;?;6@>@CCC?5;8;6=8?<??B@C:>C3:@@BB
@9MJ
CAGTACGTGACGGAAGAATTTTAGGTGTTCTTTTGCTTGACAGCAGGAAGATTGGATTAACCCTCACAGCTTCTATTCCCCGGGCCCCTGATACTACTACT
+
@@@FDBDDFHDHHBHIH<HHIJIJJGG3?GIIFIIJJJJIGIEHFGE=FGIGGIJIJJDC@EH>HAEEHDFFFBB>C;>;69>??8><<?C@CCDDDDAC:
@9MK
CTTAATTCTTGGACCCACAGAAGAGTGTCTTGCCAACACTCCCCCATCTCATGCCATCCATAGCTCACAGCTTCTATTCCCCGGGCCCCTGATACTACTAC
+
<@@FFFFFDHHFFIJIIIIGJJGEE+AFFHIDGIEEFHHGGGHIEBHGCFFHGGGGHGHGAGGHGGII>;AEEFFDDD;?CAA8;?BBBDB9@>AACC>C3
@9ML
GCAAAATTTGCAGAAAGTACAGAAAGTTCTTATATATCCTCTCCCCAGCTCACAGCTTCTATTCCCCGGGCCCCTGATACTACTACTACTACATGGACGTC
+
CCCFFFFFHHHHHIJJJHHJGHCGHHBHHIJJIIGGIIIJJJJJHIIJJJIJJIJJJJJIIJJIIIJJJHHFF>CACCACDDDDDDDDDCCDDDDC:>@>@
@9MM
AACAGACAGGACTCCCTGCCCTCGTGAAGAATGCGTTCTGTAGGACGAGACGAAGCTTAAATAACTCACAGCTTCTATTCCCCGGGCCCCTGATACTACTA
+
@@@FDEDDH@FHBGGGB>GDHGJDGGEFECFGGGHHIJ?G@?BHIHIIIE;;EHCDCFFDFDEECA@ADDDDCDDDDEEE:>A@BBDDB>BB<CCCDDC@:
@9MN
CTTTCAGAGCACAAATGCAGGATCTTTCTCCAGTACGTGACGGAAGAATTTTAGGTGTTCTTTTGCTTGACAGCAGGAAGATTGGATTAACCCTCACAGCT
+
@<BDDFAABBFDHBFBEGCFHFHJGIEHFIDG@9C<?:?8DADHHIICBBDFF;F)=@F<FAGCHFGGGHEAHEEDEB@ABEEC9>CC<@ACBBB5<>C##
@9MO
CAAAATTTGCAGAAAGTACAGAAAGTTCTTATATATCCTCTCCCCAGCTCACAGCTTCTATTCCCCGGGCCCCTGATACTACTACTACTACATGGACGTCT
+
@CCFFFFFHHHHHJGCCCEIJJGJJHGIGHIJIJIIIIIIGGIIHGDHEFDFHGIJJJJGIIHIII>EIFFD@DBCCCDDDDDCC@CCCDCDDDCCCB5><
@9MP
TTTAGGTTTAGAGCAAAATTTGCAGAAAGTACAGAAAGTTCTTATATATCCTCTCCCCAGCTCACAGCTTCTATTCCCCGGGCCCCTGATACTACTACTAC
+
<@@FFFFFHFAFHBHGIGIGHIJJJGIEGHGEFEGEHG<F@GIDHGBBFGDEGGCHGIECHEIJIGDHEGIJIG:@@DHH/9=;;:A<<>C@ACDDACCC3
@9MQ
CCGACGGGGAATTCTCACAGGAGACGAGGGGGAAAAGGGTTGGGGCGGATGCACTCCCTGAGGAGACGGTGACCGTGGTCCCTTTGCCCCAGACGTCCATG
+
@CCFFFFFHHHHHIJJJJJJIJIGHIJJJJJJFHHHFFFBEDDDDDDDDDDDCDDDDDDDDDDDDDBDD5ABDDD@DD?CDDDCCCDDDD@BBBD@BB?CC
@9MR
CGACGGGGAATTCTCACAGGAGACGAGGGGGAAAAGGGTTGGGGCGGATGCACTCCCTGAGGAGACGGTGACCGTGGTCCCTTTGCCCCAGACGTCCATGT
+
@@@DF<@ACDBDFIGIIGGGIEG;C?DGHGHEG@GEGEE@DBC?BD@8@9BCAC>CB?CDDBA<18?3&82>:;)<&23>?A@@A:CC78?BBB85?@@##
@9MS
GTTTTTAGGTTTAGAGCAAAATTTGCAGAAAGTACAGAAAGTTCTTATATATCCTCTCCCCAGCTCACAGCTTCTATTCCCCGGGCCCCTGATACTACTAC
+
BB@FFFFFHHHHHHJIJIIJIJJJJJIJJIIIGHIIJIIII?DHIJIJEIEGGGIJJHIGHJIIJIIGJJGIJJJIHHHCHFFDDBBBDDDCD:>CCDDDA
@9MT
TTTCAGAGCACAAATGCAGGATCTTTCTCCAGTACGTGACGGAAGAATTTTAGGTGTTCTTTTGCTTGACAGCAGGAAGATTGGATTAACCCTCACAGCTT
+
@@@DD8:BDF?FF@EDF::F;@GHGE@HGE>AF>G7)?DFCGIEI;39B>BFE<=B8@G;CF@D=ECHFHHEE>???B;@@>C=CCCC:-55<<<@AC2>>
@9MU
GTTTAGAGCAAAATTTGCAGAAAGTACAGAAAGTTCTTATATATCCTCTCCCCAGCTCACAGCTTCTATTCCCCGGGCCCCTGATACTACTACTACTACAT
+
@@BFFFFFGFHHHJJJJJJJIIIHFHIGIIJJGEHHIJEIIJIJGGGIEGIJHIJIIIGIGIIIJJGDIIHH;@EEB'9>/=?=:@@@CCCCDDCCACDD3
@9MV
CTGGAAGGCCGGTTTCTTCCCACTTGGAGTGAGGAGCTGGGCACCGGGCTCTAGTGGCCAATGGTCCATGAGCTTGATTTTCAGAACTTAACTGAAAGTAA
+
@C@FFFFFHHHHFIIGIJJJJJJJJIIIIGHJDIIJIJJJJIIJJIEIIHHHGFFEFFEEDECDDDDCDDDDDDDDBDDEDEDC@CDDDDCDCCDDDD@@4
@9MW
GGGAAAAGGGTTGGGGCGGATGCACTCCCTGAGGAGACGGTGACCGTGGTCCCTTTGCCCCAGACGTCCATGTAGTAGTAGTAGTATCAGGGGCCCGGGGA
+
@@@DDDDDFH:?D@HGIHG;@GIGGHEHHCE;=BBB2;?<3=;CCB8?B5>C@C>AC:>@BBB<<;88??DC4>@@CA:BDCC@BDCDACCB@5<BBBBB5
@9MX
GTTTGGGGACTTTCAGAGCACAAATGCAGGATCTTTCTCCAGTACGTGACGGAAGAATTTTAGGTGTTCTTTTGCTTGACAGCAGGAAGATTGGATTAACC
+
CCCFFFFDACFHHJJIHJJJJJJIJJJJJJGIJJJJJJJIHIIHIJHGHJGHGGIIJJIJIHIHCEHFFFFFFFEEEEEEDDDDDDDDDDDDDDDDDDDDD
@9MY
GGCGGATGCACTCCCTGAGGAGACGGTGACCGTGGTCCCTTTGCCCCAGACGTCCATGTAGTAGTAGTAGTATCAGGGGCCCGGGGAATAGAAGCTGTGAG
+
CCCFFFFFGHHGHJJIJGGGGHEHIIDH?GII:FHFHIIGIBGIIGHEGHHH;EBBCE@DEADE>BECCDB>>CDDDDDCDDDBDB>92>@>34>:AACD:
@9MZ
GGCGGATGCACTCCCTGAGGAGACGGTGACCGTGGTCCCTTTGCCCCAGACGTCCATGTAGTAGTAGTAGTATCAGGGGCCCGGGGAATAGAAGCTGTGAG
+
CCCFFFFFGHHHGJJJJJJJJJHIJIFHDHIJJIIHIIIIJJIJJJJIJIEHHHFFFFFFEDFEEFEEFEEEEDEEDDDDDDDDDDBB@CCDDDDDDCCD@
@9N0
GGTGGATGCACTCCCTGAGGAGACGGTGACCGTGGTCCCTTTGCCCCAGACGTCCATGTAGTAGTAGTAGTATCAGGGGCCCGGGGAATAGAAGCTGTGAG
+
CC@FFFFFGHHHHJJIJIJIGIGGIIGHIJGIFGHDHIJIJJJJJJJJIFCH@EHEEHEHHEFFDFFFFFFEEEEEEDBDDDD?BD<9ACC@CCDDD@CA@
@9N1
CACTCCCTGAGGAGACGGTGACCGTGGTCCCTTTGCCCCAGACGTCCATGTAGTAGTAGTAGTATCAGGGGCCCGGGGAATAGAAGCTGTGAGCTGGGGAG
+
@@@FDADFA8FDHFEBHB8CGHGGG@B?FFHGIHFDIIECFGGIEH@;;FA>ECGHGAEEHFHEEHHBDB?AAB@BBB59ACC@>@C:>4>:43:?A@@8>
@9N2
GTAAACATCGTGACCAGAAATCCTGGAGATCCACGAAGGCAACTACAAAGACTATGAAGGGAAACTACAGAAGTGGTTTTCTTAAAAAAATATACAGGCTA
+
<@?DBDDDHHADHHE:AFHGCGHIJJ@G@E9EHGBH@DH)?DBD@F9@HGBDG=D>GCCEG=CCEFHB7;37;;>;@1;5(;;>CACC8<BCED@>@####
@9N3
GGGGGAAAAGGGTTGGGGCGGATGCACTCCCTGAGGAGACGGTGACCGTGGTCCCTTTGCCCCAGACGTCCATGTAGTAGTAGTAGTATCAGGGGCCCGGG
+
CCCFFFFFGHHHFHGIJJGIJIBHEEFHHFFFFCCCCDABDD;ABCDD@BBACDDC@CACDDBDDABBBDD?@A@CD>CD:@C3>A@@>>>:CBDDDDDDD
@9N4
CGAAGGCAACTACAAAGACTATGAAGGGAAACTACAGAAGTGGTTTTCTTAAAAAAATATACAGGCTATTTTTAGAGTGTTTTTAGGATTAGAGCAAAATT
+
@@<D;@:A;FHHHIIF@GHIIIEH?FBFG<;;DFB?G4FE??FBBDC<4BDFCHIBBCHAEHH3ABB@C>;>A=(.6;;@CCC;?C:(:>AACC@@AC?C>
@9N5
CGGATGCACTCCCTGAGGAGACGGTGACCGTGGTCCCTTTGCCCCAGACGTCCATGTAGTAGTAGTAGTATCAGGGGCCCGGGGAATAGAAGCTGTGAGGG
+
;@@D?DDDDDFBFGGGIIGBFHHBHIHIII:DEGGGFGHEG<BGHEH;@@FGIG@EAEF7)=;BDB7;7;@CEA:A????BB<@<BB>@############
@9N6
GGCGGATGCACTCCCTGAGGAGACGGTGACCGTGGTCCCTTTGCCCCAGACGTCCATGTAGTAGTAGTAGTATCAGGGGCCCGGGGAATAGAAGCTGTGAG
+
@<?DB:@@FFFFDBFGFEE1+??CG0):BFA@FGF?8BBA=CF<CFFEI<CECB?BDD??ADDA>BD;B@;@BBBBB9?B@B&09-5&+>A(:@3::>?:A
@9N7
CGAGGGGGAAAAGGGTTGGGGCGGATGCACTCCCTGAGGAGACGGTGACCGTGGTCCCTTTGCCCCAGACGTCCATGTAGTAGTAGTAGTATCAGGGGCCC
+
@BBFFFFFHHHDHJJHIJJJIJJHFDDBDDDDDDDCCCDDDBDDDBBDDDDDDDBDDDDDDDDCDDBDD?B@DD?BC@CDACDB>C@B@@BCDDCD<@@B5
@9N8
GCCCCCTCTCAGGACTGATGGGAAGCCCCGGGGGCTGCTGATGTCAGAGTTGTTCTTGTATTTCCAGGAGAACGTGATGGGGGAGGGAGGGTAGCCGTGTG
+
+11A:@DDHA+2A<EGE<FA3<B@F@@):?DB('5=<((6(;3@>A@;5;;;(5:;,:@A>;C5(5A<AB###############################
@9N9
GGACAGCACTAACAGAGTTATGTGGTATTAGTCTGTCTGGATCTTCATAAGAAGACAACAGGAGTGGGTGGCTTAAACAACAAATATTGATTTTCTTAAAA
+
CCCFFFFFHHHHHJJIIGHIJJHIIFHHJIJGJJJJJIJJJJJJJJJJJJIJJJJJJJJJJGII@FIIEGHGHFE@@CFCDBDDDCDEEDDCCDDDACC@5
@9NA
CCAGCACTAACAGAGTTATGTGGTATTAGTCTGTCTGGATCTTCATAAGAAGACAACAGGAGTGGGTGGCTTAAACAACAAATATTGATTTTCTTAAAATT
+
CCCFFFFFHHHHHGJHIJJJGIJEHJIIIIIJJJJJIIHIIJJIJJJJJIHGIJJIJIJHIJFGHJFHIHHHHFFFFFFDDEEEFFEDEDEADDDDCDDEC
@9NB
TGCTCACATAGCTCCACTGTAAAAACAAGTGTTTTTTGGACCCGAATTTGGAGATGGTGACTGGATTCATAAGGAGTGGGTGGGAATTTTTGCTCCCTTCT
+
=+=:+ABBB???DGI>ACEF@HGCHDA@;??H?CHIADD9B?B?D@CACHGIIIH)3..=?>CAAEB>).7?>3(6(5=2338'93<C:A@&:+>:@3@##
@9NC
GCCATTCTTTCCTGGGCATCCCGGGGATCCCAGAGCCGGCCCAGGTACCAGCAGGCAGAGAAGAGGCCATGTGGAGACATAGTGCACTAGAAGGTGGCGCA
+
B;=DAD?BDH<?:AAGFEGIGEB<GIA@G):?FAFH@FG6;;;AH=3=CED?;;=>?CDDC>?C<28?ACC>CD3(9??A@>>:A4>:@>3>483>@####
@9ND
GGAAAATCCAGAGACAGCACAGGTGAGGGAGAGGGTCTGCGAGGGCTCCACCAGGCCAAGAGTGCACTGTTTTATGTGGAAATCTGAGAGATGTGCCCAGC
+
CC@FFFFFHBFHHIJJJJJIIHIBFFHJJEHHJJJHHGIJJJJJJJJJJIHHHHFFFFDDEEAACDDDDCDDDDDDFEDDD@CDDECDDDDDCDDDACA@A
@9NE
CCAACAGGGACATGACAAGTTTTTATATCAGAACTACTATTTTTTACCTGTTTTATGTGGAAATCTGAGAGATGTGCCCAGCCTCAGGAGGCTAATTCTCC
+
@@CADFFF@AFFGHGGBHG?DHCCFGHH@GEAEGFG99CDGHGIIDGHHIHDFC<BBF@FD;=CHEECEGCCHDHH)).;BCDDCE>;CB??A:3:@A;;5
@9NF
CTTTCCTGGGCATCCCGGGGATCCCAGAGCCGGCCCAGGTACCAGCAGGCAGAGAAGAGGCCATGTGGAGACATAGTGCACTAGAAGGTGGCCCAGTGCAA
+
@<?DDDDDD?DHHBFAHGDGAACGFDGB9@FGGGEHIII;DHIHEHHF9<?=?A@?A;;;?@BCCD:CCB><?3>>4>:@C>AAA@@1(+((8A@B:>>@#
@9NG
TGGAAATCTGAGAGATGTGCCCAGCCTCAGGAGGCTAATTCTCCATCCAGGGGACAGCACTAACAGAGTTATGTGGTATTAGTCTGTCTGGATCTTCATAG
+
@C@DFFFFHDADFGGDGGGIIJDIEGGGIGG>GGHIHIIGGIJ<@9??*???D@GGDEG@C=C:?A?=A??@;CD@>AEEDDEA3;>>ACCCCC#######
@9NH
TGGAAATCTGAGAGATGTGCCCAGCCTCAGGAGGCTAATTCTCCATCCAGGGGACAGCACTAACAGAGTTATGTGGTATTAGTCTGTCTGGATCTTCATAA
+
@?@DDDDDHFHDHBHIGGGIGGGCII@EG9FGIIDIIIIGGGCGG@GIG@E>DBADCGIG@CEHHH>?7=BBD;>B>>;;>C>A>A;@C;ACC:53;CC##
@9NI
CCCAGCCTCAGGAGGCTAATTCTCCATCCAGGGGACAGCACTAACAGAGTTATGTGGTATTAGTCTGTCTGGATCTTCATAAGAAGACAACAGGAGTGGGT
+
@CCFFFFFHFHGHJIIJJJJIEHHIJJIIJJJIJIIJJJJJJIJIJIBFC=FDHHIJFGHIIJJIJJHHHHHEFFFCDEEACCDDE>5>CBDBDBBCB<B<
@9NJ
GGGGATCCCAGAGCCGGCCCAGGTACCAGCAGGCAGAGAAGAGGCCATGTGGAGACATAGTGCACTAGAAGGTGGCCCAGTGCAAGCCAGGAAGAAGCCGC
+
@;?B;DD;+C:DDDFDHGHIIGGGGEG>DGHCCGDADHDC;C>==C=@=@7===?EBED>;7>;>@CC>>@95;??<??BCCC<>C<?C8?(8<?CCC<99
@9NK
TTCTCCATCCAGGGGACAGCACTAACAGAGTTATGTGGTATTAGTCTGTCTGGATCTTCATAAGAAGACAACAGGAGTGGGTGGCTTAAACAACAAATATT
+
@@CDFDFFGGHGBGHDHHDEGGJJJJJIAEDGHBD9BGDDHHEIIJJEIE<DBBDFCGHGEFIICHIEGGIHCEFHF3?AB=>@BDDA5:AABD<AA@:CD
@9NL
CGGAGAACTGCCATTCTTTCCTGGGCATCCCGGGGATCCCAGAGCCGGCCCAGGTACCAGCAGGCAGAGAAGAGGCCATGTGGAGACATAGTGCACTAGAA
+
@?@DBDDDHGBHBHGJIJIJEGHFGEHCHCHFGGHGIJDFHHGG@GGGHF9BBDCEEEDDDDDDDDDDDACDCA1888>CC>C>A9?9A:::>>C@CCAC>
@9NM
GCTTAAACAACAAATATTGATTTTCTTAAAATTCTGCAGTCTGAATGTTGAAGATTAGTGTGCTGGCAGGGCTGGTTCTTGGCGCGGCTTCTTCCTGGCTT
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJIJJJIJJJIJIJHIJJIJJJIJJJJJIIJIIIIJGJIJJJJBHFCCAECB>@ACDDDB>9@CCCC:A??<
@9NN
CTGCCATTCTTTCCTGGGCATCCCGGGGATCCCAGAGCCGGCCCAGGTACCAGCAGGCAGAGAAGAGGCCATGTGGAGACATAGTGCACTAGAAGGTGGCC
+
CCCFFFFFHGHGHJIIJJJJJJJJJJIIJJJJJJJIJJHJJJJJJHGEHHFDFFFEDDDDDDDDDDDDDDDDDCDDDDCDDDDDCCCDDDDDDCDBAC?<A
@9NO
CGGAGAACTGCCATTCTTTCCTGGGCATCCCGGGGATCCCAGAGCCGGCCCAGGTACCAGCAGGCAGAGAAGAGGCCATGTGGAGACATAGTGCACTAGAA
+
CCCFFFDFHHHHHJJJJJJJJIJJJJJJJJJGIGIJJJJJJJIJJJIJHHBEFDCEEEECDDDBDDDDDDDDDDD@DDDDEDDDDCBCDDDDACCACDDD@
@9NP
CCCAGAGCCGGCCCAGGTACCAGCAGGCAGAGAAGAGGCCATGTGGAGACATAGTGCACTAGAAGGTGGCCCAGTGCAAGCCAGGAAGAAGCCGCGCCAAG
+
CCCFFFFFGHHHHJJJJHIJJJIJJJJJJJJJJJJJJJIJDIJHIGIIGIGIHHEHGHHFFFFFEEACCDDDDDCDDDDC?BDDDDDD?AC?<-<>DDD98
@9NQ
CCTGGCTTGCACTGGGCCACCTTCTAGTGCACTATGTCTCCACATGGCCTCTTCTCTGCCTGCTGGTACCTGGGCCGGCTCTGGGATCCCCGGGATGCCCA
+
CC@FFFFFFDHHFGII?H:FEEHGGGEGGDEHIIIGFHIGHEIAFGGEG@DHH?C4B>EHGIIECG@DGGGHHHADCC@>BCCCC9:8?ABBBB><?<AC#
@9NR
CCAGCACTAACAGAGTTATGTGGTATTAGTCTGTCTGGATCTTCATAAGAAGACAACAGGAGTGGGTGGCTTAAACAACAAATATTGATTTTCTTAAAATT
+
CCCFFFFFHHHHHGJHIJJJGIJEHJIIIIIJJJJJIIHIIJJIJJJJJIHGIJJIJIJHIJFGHJFHIHHHHFFFFFFDDEEEFFEDEDEADDDDCDDEC
@9NS
CGGAGAACTGCCATTCTTTCCTGGGCATCCCGGGGATCCCAGAGCCGGCCCAGGTACCAGCAGGCAGAGAAGAGGCCATGTGGAGACATAGTGCACTAGAA
+
@?@DBDDDHGBHBHGJIJIJEGHFGEHCHCHFGGHGIJDFHHGG@GGGHF9BBDCEEEDDDDDDDDDDDACDCA1888>CC>C>A9?9A:::>>C@CCAC>
@9NT
CGGAGAACTGCCATTCTTTCCTGGGCATCCCGGGGATCCCAGAGCCGGCCCAGGTACCAGCAGGCAGAGAAGAGGCCATGTGGAGACATAGTGCACTAGAA
+
CCCFFFDFHHHHHJJJJJJJJIJJJJJJJJJGIGIJJJJJJJIJJJIJHHBEFDCEEEECDDDBDDDDDDDDDDD@DDDDEDDDDCBCDDDDACCACDDD@
@9NU
CGGAGAACTGCCATTCTTTCCTGGGCATCCCGGGGATCCCAGAGCCGGCCCAGGTACCAGCAGGAGGACACATCCTCACCCTGCAGAAGCCTGAGTGTCAC
+
C@CFDDFFHHGB>FECGIDF<HHGGGE;CF@?DEAADFHG>BGHIGJGBHD?DC;>CC>>??ABB@@1?CACC:>@>>BB??9?CAC9?C<:<<A######
@9NV
GAAGCACCCTGGGTGCCATGGAGCCTAAGGAAGTTTCAGCAAGGCCCTAAGGGGTTCTGGAGCCAAAGTCAGTCATCAGAGGAGTCCCATGACTCCCAGGA
+
?@@D@DB;DBAC=21C?EC@CGGGICHIH9BDHFDHGG@FGG9D@?DGIGG<F<AAGGH@@EBAEBDE;3>>;@CDCC;:55;<<A::::?CCCCCBCC7<
@9NW
GAACGGTCAGTTTAGGGGCTGGTGCAAAGGATGAGTTGCACATTGTTGAAGCAGAGGCAATGAATTACGAAGGCAGTCCAATTAAAGTAACACTGGCAACT
+
CCCFFFFDFHHHHJJJJJJBIJ@GGAGGGGE@GGGHIIGGGDAHGIICGEHIH9=;FFCE;@DGHFEHHFF?BDEDDCC:>CCCDDCFDDCCCCDBD9>A#
@9NX
CAATGTTCTGGTGGTTGAATTTGCTGATGATCAGGGCTTCCATGAGGAAATCCAGTTCGTCCTGTTCAGAGCACACTTCAGGCAGCGTCTTCACAGCCACT
+
=8:DDDDDDDF<DGGGIEIGHG@@HIBHEIGGG>FCFHDHIIH@GBDCHIDIDFHIIGGCHGIEIGHIAEGB?CHHFCCED7;=;?;=?@@>CCCCBB@A:
@9NY
CCAGCATGGCCAGGGAGGAGGGCTGGCTCGGGCGAGGGCGGGTCTCTCGGAGGAAGGACTTGAGGTCTCCCCCCGCCATGAGCTCCAGCAGGATGAACCGG
+
CCCFFFFFHGHHHJJGIJGIJJJIIIIAHHIJJJIIHDFDDDDDCDDDDDBDDBDDBBDCDDDDDDDDDDDDDDDDDDDDDDDCDDDDDDDD?CDDCCBBB
@9NZ
GTTGAAGTGTGGTTCAGGGCCAGTGCATATTAGTGGACAGCACTTAGTAGTGTACCGCCGGAAGCACCAGGAGCTGCAAGCCATGCAGATGGAGCTGCAGA
+
@@@;DDFABAFDHGJIIGHGGCHBFGCHGHFIICGAEGIGIHIEGII9BF<BB@<FHIHIHH/9BCE?B(=??B?CDCC><@C@CC>++,:@CBABCC###
@9O0
GGCAGGGATTGCAGGCTCACCCCAATGCAGCGAACAATGTTCTGGTGGTTGAATTTGCTGATGATCAGGGCTTCCATGAGGAAATCCAGTTCGTCCTGTTC
+
CCCFFFFFHFHHHHHGIIJJIJJIGIIIIII6:@GA??FBFHIIIGHEAGHHIEHGHHHFDFFFEFEECACBBCDDEACCA@BDDDCDDCDCB@DBDCCD@
@9O1
TGAATTTGCTGATGATCAGGGCTTCCATGAGGAAATCCAGTTCGTACTGTTCAGAGGACACTTCAGGCAGCGTCTTCACAGCCACTTGCAGGGGGCTTGGG
+
?1?B??DBF<+<C+2,,<C@?AEF9AF@+922??E<C<?C*19:))8B99?<?9??(=@F><=/=@37.-(-(5'?>>>;:;==@AB##############
@9O2
CTTAAGGTTGAAGTGTGGTTCAGGGCCAGTGCATATTAGTGGACAGCACTTAGTAGTGTACCGCCGGAAGCACCAGGAGCTGCAAGCCATGCAGATGGAGC
+
?@@DFFFFHHDHHFHDGHGIJJIJJIIJJHIIJJIJJJGAGIIJJJJJJHGIJJJJHIHIIGHIIHFFDDDDDBDDBDDDDDDDCCBBDDDDDCDCDCD@?
@9O3
CAGCCCCCTGGAGCTGAGGCTCCTCTCCCTGTACCGCCCCCCACTGGCACCGCTGCTGCCCCTGCCCCCACTCCCAGCCCCGCAGGGGGCCCTGACCCCA
+
IIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIII
@9O4
GCCGGGGCAGGTTGGGAGACCCCCTCTGCCGGTGAGGTGGGGTCAGGGCCCCCTGCGGGGCTGGGAGTGGGGGCAGGGGCAGCAGCGGTGCCAGTGGGGG
+
IIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIII
@9O5
CCCGCAGGGGGCCCTGACCCCACCTCACCGGCAGAGGGGGTCTCCCAACCTGCCCCGGCGCGCGGGGATTTCGCCTACGCCGCCCCGGCTCCTCCGGACG
+
IIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIII
@9O6
GGGGCAGGTTGGGAGACCCCCTCTGCCGGTGAGGTGGGGTCAGGGCCCCCTGCGGGGCTGGGAGTGGGGGCAGGGGCAGCAGCGGTGCCAGTGGGGGGCG
+
IIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIII
@9O7
GGCCCTGGTCATGCAGCTCTTTCAGGACCATGGCTTCTTCCCGTCAGCCCAGGCCACAGCCGCCTTCCAGGCCCGCTATGCAGACATCTTTCCCTCCAAG
+
IIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIII
@9O8
CAGCCCCCTGGAGCTGAGGCTCCTCTCCCTGTACCGCCCCCCACTGGCACCGCTGCTGCCCCTGCCCCCACTCCCAGCCCCGCAGGGGGCCCTGACCCCA
+
IIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIII
@9O9
CTCCTCTCCCTGTACCGCCCCCCACTGGCACCGCTGCTGCCCCTGCCCCCACTCCCAGCCCCGCAGGGGGCCCTGACCCCACCTCACCGGCAGAGGGGGT
+
IIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIII
@9OA
CGTGAGGTGCGCCAGAAGATCATGCAGGCTGCCACTCCCACGGAGCAGCCCCCTGGAGCTGAGGCTCCTCTCCCTGTACCGCCCCCCACTGGCACCGCTG
+
IIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIII
@9OB
GCGGGCCCAGGCTGTGCCACCGCGCAGGGGCCCGGCAGGCCGTCGCGCTGCGGGTCCCGGTCCTCCCGGCTTTTGCCCGGGTGCGGAGGCCACCGAGGAG
+
IIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIII
@9OC
TGCAGTTGAAGATCCGTGAGGTGCGCCAGAAGATCATGCAGGCTGCCACTCCCACGGAGCAGCCCCCTGGAGCTGAGGCTCCTCTCCCTGTACCGCCCCC
+
IIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIII
@9OD
GCAACCTCTCCTAGAAACGGAGGCCCCGGGGGAGCTGGAGGCCTCGGAAGAGGCCGCCTCGCTGCGATCCCTCAGGGTTGGCTGTAGTCACCGTATGGGGG
+
CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJHFFEEEEEDDDDDDDBDDDDDDDDDDDDDDDDDDBDDDDDDDDDD<ABDDDDBCDDEDDDDDDBDCDDD
@9OE
CGCAACCTCTCCTAGAAACGGAGGCCCCGGGGGAGCTGGAGGCCTCGGAAGAGGCCGCCTCGCTGCGATCCCTCAGGGTTGGCTGTAGTCACCGTATGGCG
+
?@@DDDEDHBHHHGGEEED;;EEGBEFFAG@?:?<AAAC????BCBCC?<9<8?<80:<@75<BB5;>A78AACBA9+3(00@@?8::@ADCCB22<?###
@9OF
CCGGAGTTTCTGCAGCAGGCGCAACCTCTCCTAGAAACGGAGGCCCCGGGGGAGCTGGAGGCCTCGGAAGAGGCCGCCTCGCTGCGATCCCTCAGGGTTGG
+
CCCFFFFFHHHHGJJJJJJIGGIJIJJJJIJIIJIJJJJJIIIIIJJIHFDDBDDDDDDDBBBDDDD@DB@BB?@B<BBBDD00<55<8?CCD8?CD3859
@9OG
CTCCTAGAAACGGAGGCCCCGGGGGAGCTGGAGGCCTCGGAAGAGGCCGCCTCGCTGCGATCCCTCAGGGTTGGCTGTAGTCACCGTATGGGGGAAGCCTG
+
@@CFFFFFHHGHGIIIIJJJIGIJJGGACHCBBBACCEDD@B@BBDBDD@:<BDD@BDB;?8<<@CBDDD38;B>>?A@C4:@CCD++++9A?@&5?2<4<
@9OH
CGCAACCTCTCCTAGAAACGGAGGCCCCGGGGGAGCTGGAGGCCTCGGAAGAGGCCGCCTCGCTGCGATCCCTCAGGGTTGGCTGTAGTCACCGTATGGGG
+
@CCFFFFFHHHHHJJJJJJJJJJJJJJJJIJFHBDCEEEDDDDDDDDBBD@DDDDDDDDBBDDDDDDDDDDDDD?CCD?ABDDDBACC>CD@@?2?BCC1?