DNA-seq pipeline with Sentieon + Varscan.
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5 年之前
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  1. {
  2. "{{ project_name }}.fasta": "GRCh38.d1.vd1.fa",
  3. "{{ project_name }}.ref_dir": "oss://pgx-reference-data/GRCh38.d1.vd1/",
  4. "{{ project_name }}.dbsnp": "dbsnp_146.hg38.vcf",
  5. "{{ project_name }}.dbsnp_dir": "oss://pgx-reference-data/GRCh38.d1.vd1/",
  6. "{{ project_name }}.SENTIEON_INSTALL_DIR": "/opt/sentieon-genomics",
  7. "{{ project_name }}.dbmills_dir": "oss://pgx-reference-data/GRCh38.d1.vd1/",
  8. "{{ project_name }}.db_mills": "Mills_and_1000G_gold_standard.indels.hg38.vcf",
  9. "{{ project_name }}.docker": "registry.cn-shanghai.aliyuncs.com/pgx-docker-registry/sentieon-genomics:v2017.11.04",
  10. "{{ project_name }}.varscan_docker": "registry.cn-shanghai.aliyuncs.com/pgx-docker-registry/varscan2:v2.4.3",
  11. "{{ project_name }}.sample": "{{ sample_name }}",
  12. "{{ project_name }}.tumor_fastq_2": "{{ tumor_fastq_2 }}",
  13. "{{ project_name }}.tumor_fastq_1": "{{ tumor_fastq_1 }}",
  14. "{{ project_name }}.normal_fastq_1": "{{ normal_fastq_1 }}",
  15. "{{ project_name }}.normal_fastq_2": "{{ normal_fastq_2 }}",
  16. "{{ project_name }}.regions": "{{ regions }}",
  17. "{{ project_name }}.disk_size": "{{ disk_size }}",
  18. "{{ project_name }}.cluster_config": "{{ cluster if cluster != '' else 'OnDemand ecs.sn1ne.4xlarge img-ubuntu-vpc' }}"
  19. }